-- dump date   	20140619_113421
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
357544000001	hypothetical protein; Provisional; Region: PRK10236
357544000002	Domain of unknown function (DUF3944); Region: DUF3944; pfam13099
357544000003	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735
357544000004	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
357544000005	putative RNA binding site [nucleotide binding]; other site
357544000006	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
357544000007	homopentamer interface [polypeptide binding]; other site
357544000008	active site
357544000009	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
357544000010	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeB; cd00884
357544000011	active site clefts [active]
357544000012	zinc binding site [ion binding]; other site
357544000013	dimer interface [polypeptide binding]; other site
357544000014	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
357544000015	active site
357544000016	dimer interface [polypeptide binding]; other site
357544000017	pantoate--beta-alanine ligase; Region: panC; TIGR00018
357544000018	Pantoate-beta-alanine ligase; Region: PanC; cd00560
357544000019	active site
357544000020	ATP-binding site [chemical binding]; other site
357544000021	pantoate-binding site; other site
357544000022	HXXH motif; other site
357544000023	similar to hypothetical protein
357544000024	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544000025	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
357544000026	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
357544000027	ring oligomerisation interface [polypeptide binding]; other site
357544000028	ATP/Mg binding site [chemical binding]; other site
357544000029	stacking interactions; other site
357544000030	hinge regions; other site
357544000031	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
357544000032	oligomerisation interface [polypeptide binding]; other site
357544000033	mobile loop; other site
357544000034	roof hairpin; other site
357544000035	DNA primase, catalytic core; Region: dnaG; TIGR01391
357544000036	CHC2 zinc finger; Region: zf-CHC2; pfam01807
357544000037	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
357544000038	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
357544000039	active site
357544000040	metal binding site [ion binding]; metal-binding site
357544000041	interdomain interaction site; other site
357544000042	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
357544000043	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
357544000044	Ligand Binding Site [chemical binding]; other site
357544000045	TrbC/VIRB2 family; Region: TrbC; cl01583
357544000046	type IV secretion/conjugal transfer ATPase, VirB4 family; Region: VirB4_CagE; TIGR00929
357544000047	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
357544000048	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
357544000049	Walker A motif; other site
357544000050	ATP binding site [chemical binding]; other site
357544000051	TraM recognition site of TraD and TraG; Region: TraG-D_C; cl17375
357544000052	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3014
357544000053	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cd00588
357544000054	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
357544000055	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
357544000056	active site
357544000057	phosphorylation site [posttranslational modification]
357544000058	intermolecular recognition site; other site
357544000059	dimerization interface [polypeptide binding]; other site
357544000060	carboxynorspermidine decarboxylase; Region: nspC; TIGR01047
357544000061	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Carboxynorspermidine Decarboxylase; Region: PLPDE_III_CANSDC; cd06829
357544000062	dimer interface [polypeptide binding]; other site
357544000063	active site
357544000064	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
357544000065	catalytic residues [active]
357544000066	substrate binding site [chemical binding]; other site
357544000067	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
357544000068	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
357544000069	active site
357544000070	lipid A phosphoethanolamine transferase; Reviewed; Region: PRK09598
357544000071	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
357544000072	Sulfatase; Region: Sulfatase; pfam00884
357544000073	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544000074	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
357544000075	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
357544000076	dimer interface [polypeptide binding]; other site
357544000077	active site
357544000078	citrylCoA binding site [chemical binding]; other site
357544000079	NADH binding [chemical binding]; other site
357544000080	cationic pore residues; other site
357544000081	oxalacetate/citrate binding site [chemical binding]; other site
357544000082	coenzyme A binding site [chemical binding]; other site
357544000083	catalytic triad [active]
357544000084	isocitrate dehydrogenase; Validated; Region: PRK07362
357544000085	isocitrate dehydrogenase; Reviewed; Region: PRK07006
357544000086	Protein of unknown function (DUF1523); Region: DUF1523; pfam07509
357544000087	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
357544000088	AAA domain; Region: AAA_26; pfam13500
357544000089	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
357544000090	Ligand Binding Site [chemical binding]; other site
357544000091	Uncharacterized conserved protein [Function unknown]; Region: COG2127
357544000092	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
357544000093	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
357544000094	Walker A motif; other site
357544000095	ATP binding site [chemical binding]; other site
357544000096	Walker B motif; other site
357544000097	arginine finger; other site
357544000098	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
357544000099	Walker A motif; other site
357544000100	ATP binding site [chemical binding]; other site
357544000101	Walker B motif; other site
357544000102	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
357544000103	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
357544000104	tetramerization interface [polypeptide binding]; other site
357544000105	active site
357544000106	hypothetical protein; Provisional; Region: PRK03762
357544000107	PDZ domain; Region: PDZ_2; pfam13180
357544000108	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
357544000109	Type IV secretory pathway, TrbL components [Intracellular trafficking and secretion]; Region: TrbL; COG3846
357544000110	Type IV secretory pathway, component VirB8 [Intracellular trafficking and secretion]; Region: VirB8; COG3736
357544000111	Type IV secretory pathway, VirB9 components [Intracellular trafficking and secretion]; Region: VirB9; COG3504
357544000112	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911
357544000113	VirB7 interaction site; other site
357544000114	Type IV secretory pathway, VirB10 components [Intracellular trafficking and secretion]; Region: VirB10; COG2948
357544000115	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
357544000116	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
357544000117	Substrate binding site; other site
357544000118	Cupin domain; Region: Cupin_2; cl17218
357544000119	GDP-mannose 4,6-dehydratase; Region: gmd; TIGR01472
357544000120	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
357544000121	NADP-binding site; other site
357544000122	homotetramer interface [polypeptide binding]; other site
357544000123	substrate binding site [chemical binding]; other site
357544000124	homodimer interface [polypeptide binding]; other site
357544000125	active site
357544000126	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
357544000127	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
357544000128	NADP binding site [chemical binding]; other site
357544000129	active site
357544000130	putative substrate binding site [chemical binding]; other site
357544000131	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
357544000132	dimerization interface [polypeptide binding]; other site
357544000133	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
357544000134	ATP binding site [chemical binding]; other site
357544000135	Acylphosphatase; Region: Acylphosphatase; pfam00708
357544000136	[NiFe] hydrogenase maturation protein HypF; Region: hypF; TIGR00143
357544000137	HypF finger; Region: zf-HYPF; pfam07503
357544000138	HypF finger; Region: zf-HYPF; pfam07503
357544000139	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
357544000140	Peptidylarginine deiminase and related enzymes [Amino acid transport and metabolism]; Region: COG2957
357544000141	Porphyromonas-type peptidyl-arginine deiminase; Region: PAD_porph; pfam04371
357544000142	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
357544000143	DNA methylase; Region: N6_N4_Mtase; pfam01555
357544000144	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
357544000145	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
357544000146	cofactor binding site; other site
357544000147	DNA binding site [nucleotide binding]
357544000148	substrate interaction site [chemical binding]; other site
357544000149	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
357544000150	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
357544000151	DNA methylase; Region: N6_N4_Mtase; pfam01555
357544000152	Tsp45I type II restriction enzyme; Region: Tsp45I; pfam06300
357544000153	Tsp45I type II restriction enzyme; Region: Tsp45I; pfam06300
357544000154	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
357544000155	cofactor binding site; other site
357544000156	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
357544000157	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
357544000158	Na binding site [ion binding]; other site
357544000159	Proline dehydrogenase; Region: Pro_dh; pfam01619
357544000160	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
357544000161	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
357544000162	Glutamate binding site [chemical binding]; other site
357544000163	NAD binding site [chemical binding]; other site
357544000164	catalytic residues [active]
357544000165	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
357544000166	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
357544000167	nucleotide binding site [chemical binding]; other site
357544000168	Proteins of 100 residues with WXG; Region: WXG100; cl02005
357544000169	A nuclease of the HNH/ENDO VII superfamily with conserved WHH; Region: WHH; pfam14414
357544000170	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
357544000171	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
357544000172	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
357544000173	Urease accessory protein UreH [Posttranslational modification, protein turnover, chaperones]; Region: UreH; COG0829
357544000174	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
357544000175	G1 box; other site
357544000176	GTP/Mg2+ binding site [chemical binding]; other site
357544000177	G2 box; other site
357544000178	Switch I region; other site
357544000179	G3 box; other site
357544000180	Switch II region; other site
357544000181	G4 box; other site
357544000182	G5 box; other site
357544000183	Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones]; Region: UreF; COG0830
357544000184	UreF; Region: UreF; pfam01730
357544000185	urease accessory protein UreE; Provisional; Region: ureE; PRK13261
357544000186	UreE urease accessory protein. UreE is a metallochaperone assisting the insertion of a Ni2+ ion in the active site of urease, an important step in the in vivo assembly of urease, an enzyme that hydrolyses urea into ammonia and carbamic acid. The...; Region: UreE; cd00571
357544000187	dimer interface [polypeptide binding]; other site
357544000188	catalytic residues [active]
357544000189	AmiS/UreI family transporter; Region: AmiS_UreI; pfam02293
357544000190	urease subunit beta; Provisional; Region: ureB; PRK13985
357544000191	Urease alpha-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, fungi and plants. Their primary role is to allow the use of...; Region: Urease_alpha; cd00375
357544000192	subunit interactions [polypeptide binding]; other site
357544000193	active site
357544000194	flap region; other site
357544000195	urease subunit alpha; Provisional; Region: PRK13986
357544000196	Urease gamma-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use...; Region: Urease_gamma; cd00390
357544000197	alpha-gamma subunit interface [polypeptide binding]; other site
357544000198	beta-gamma subunit interface [polypeptide binding]; other site
357544000199	Urease beta-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use of...; Region: Urease_beta; cd00407
357544000200	gamma-beta subunit interface [polypeptide binding]; other site
357544000201	alpha-beta subunit interface [polypeptide binding]; other site
357544000202	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
357544000203	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14324
357544000204	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
357544000205	active site
357544000206	substrate binding site [chemical binding]; other site
357544000207	metal binding site [ion binding]; metal-binding site
357544000208	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
357544000209	peptide chain release factor 1; Validated; Region: prfA; PRK00591
357544000210	This domain is found in peptide chain release factors; Region: PCRF; smart00937
357544000211	RF-1 domain; Region: RF-1; pfam00472
357544000212	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544000213	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
357544000214	dimer interface [polypeptide binding]; other site
357544000215	putative CheW interface [polypeptide binding]; other site
357544000216	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
357544000217	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
357544000218	23S rRNA interface [nucleotide binding]; other site
357544000219	L3 interface [polypeptide binding]; other site
357544000220	Malate:quinone oxidoreductase (Mqo); Region: Mqo; cl17341
357544000221	Predicted dehydrogenase [General function prediction only]; Region: COG0579
357544000222	NLPC_P60 stabilising domain, N term; Region: N_NLPC_P60; pfam12912
357544000223	SH3 domain of the SH3b1 type; Region: SH3_6; pfam12913
357544000224	SH3 domain of SH3b2 type; Region: SH3_7; pfam12914
357544000225	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
357544000226	NlpC/P60 family; Region: NLPC_P60; pfam00877
357544000227	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
357544000228	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
357544000229	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
357544000230	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
357544000231	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
357544000232	DNA binding residues [nucleotide binding]
357544000233	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
357544000234	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
357544000235	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
357544000236	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
357544000237	Protein of unknown function (DUF511); Region: DUF511; pfam04373
357544000238	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
357544000239	Methyltransferase domain; Region: Methyltransf_26; pfam13659
357544000240	DNA methylase; Region: N6_N4_Mtase; pfam01555
357544000241	Alpha-1,2-fucosyltransferase; Region: Fut1_Fut2_like; cd11301
357544000242	Glycosyl transferase family 11; Region: Glyco_transf_11; pfam01531
357544000243	GDP-Fucose binding site [chemical binding]; other site
357544000244	2-hydroxyacid dehydrogenase; Provisional; Region: PRK08410
357544000245	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
357544000246	NAD binding site [chemical binding]; other site
357544000247	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
357544000248	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
357544000249	pyridoxal 5'-phosphate binding site [chemical binding]; other site
357544000250	catalytic residue [active]
357544000251	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
357544000252	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
357544000253	dimer interface [polypeptide binding]; other site
357544000254	putative CheW interface [polypeptide binding]; other site
357544000255	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases and ATP sulphurylases. The domain forms a apha/beta/apha fold which  binds to Adenosine group; Region: Alpha_ANH_like; cd01986
357544000256	Ligand Binding Site [chemical binding]; other site
357544000257	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544000258	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
357544000259	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
357544000260	metal-binding site
357544000261	Cache is an extracellular domain that is predicted to have a role in small-molecule recognition in a wide range of proteins; Region: Cache_2; smart01049
357544000262	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
357544000263	dimerization interface [polypeptide binding]; other site
357544000264	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
357544000265	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
357544000266	dimer interface [polypeptide binding]; other site
357544000267	putative CheW interface [polypeptide binding]; other site
357544000268	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
357544000269	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
357544000270	active site
357544000271	metal binding site [ion binding]; metal-binding site
357544000272	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
357544000273	S-ribosylhomocysteinase; Provisional; Region: PRK02260
357544000274	cystathionine gamma-synthase/cystathionine beta-lyase; Validated; Region: PRK06176
357544000275	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
357544000276	homodimer interface [polypeptide binding]; other site
357544000277	substrate-cofactor binding pocket; other site
357544000278	pyridoxal 5'-phosphate binding site [chemical binding]; other site
357544000279	catalytic residue [active]
357544000280	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
357544000281	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
357544000282	dimer interface [polypeptide binding]; other site
357544000283	pyridoxal 5'-phosphate binding site [chemical binding]; other site
357544000284	catalytic residue [active]
357544000285	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
357544000286	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
357544000287	nucleotide binding site [chemical binding]; other site
357544000288	NEF interaction site [polypeptide binding]; other site
357544000289	SBD interface [polypeptide binding]; other site
357544000290	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
357544000291	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
357544000292	dimer interface [polypeptide binding]; other site
357544000293	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
357544000294	heat-inducible transcription repressor; Provisional; Region: PRK03911
357544000295	hypothetical protein; Provisional; Region: PRK05834
357544000296	intersubunit interface [polypeptide binding]; other site
357544000297	active site
357544000298	Zn2+ binding site [ion binding]; other site
357544000299	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2604
357544000300	flagellin B; Provisional; Region: PRK13588
357544000301	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
357544000302	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
357544000303	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
357544000304	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
357544000305	DNA topoisomerase I; Validated; Region: PRK05582
357544000306	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
357544000307	active site
357544000308	interdomain interaction site; other site
357544000309	putative metal-binding site [ion binding]; other site
357544000310	nucleotide binding site [chemical binding]; other site
357544000311	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
357544000312	domain I; other site
357544000313	DNA binding groove [nucleotide binding]
357544000314	phosphate binding site [ion binding]; other site
357544000315	domain II; other site
357544000316	domain III; other site
357544000317	nucleotide binding site [chemical binding]; other site
357544000318	catalytic site [active]
357544000319	domain IV; other site
357544000320	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
357544000321	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
357544000322	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
357544000323	Fe-S oxidoreductases [Energy production and conversion]; Region: COG0731
357544000324	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
357544000325	FeS/SAM binding site; other site
357544000326	Helicobacter pylori protein of unknown function (DUF874); Region: DUF874; pfam05917
357544000327	Helicobacter pylori protein of unknown function (DUF874); Region: DUF874; pfam05917
357544000328	phosphoenolpyruvate synthase; Validated; Region: PRK06464
357544000329	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
357544000330	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
357544000331	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
357544000332	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK12305
357544000333	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
357544000334	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
357544000335	active site
357544000336	dimer interface [polypeptide binding]; other site
357544000337	motif 1; other site
357544000338	motif 2; other site
357544000339	motif 3; other site
357544000340	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
357544000341	anticodon binding site; other site
357544000342	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
357544000343	translation initiation factor IF-3; Region: infC; TIGR00168
357544000344	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
357544000345	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
357544000346	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
357544000347	23S rRNA binding site [nucleotide binding]; other site
357544000348	L21 binding site [polypeptide binding]; other site
357544000349	L13 binding site [polypeptide binding]; other site
357544000350	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544000351	Protein of unknown function (DUF1104); Region: DUF1104; pfam06518
357544000352	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
357544000353	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
357544000354	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
357544000355	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
357544000356	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
357544000357	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase [Amino acid transport and metabolism]; Region: AroG; COG3200
357544000358	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
357544000359	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
357544000360	catalytic triad [active]
357544000361	Uncharacterized conserved protein [Function unknown]; Region: COG1556
357544000362	iron-sulfur cluster-binding protein; Region: TIGR00273
357544000363	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
357544000364	Domain of unknown function (DUF3390); Region: DUF3390; pfam11870
357544000365	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
357544000366	Cysteine-rich domain; Region: CCG; pfam02754
357544000367	Cysteine-rich domain; Region: CCG; pfam02754
357544000368	L-lactate transport; Region: lctP; TIGR00795
357544000369	L-lactate permease [Energy production and conversion]; Region: LldP; COG1620
357544000370	L-lactate permease [Energy production and conversion]; Region: LldP; COG1620
357544000371	L-lactate transport; Region: lctP; TIGR00795
357544000372	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
357544000373	DNA glycosylase MutY; Provisional; Region: PRK13910
357544000374	minor groove reading motif; other site
357544000375	helix-hairpin-helix signature motif; other site
357544000376	substrate binding pocket [chemical binding]; other site
357544000377	active site
357544000378	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
357544000379	DNA binding and oxoG recognition site [nucleotide binding]
357544000380	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
357544000381	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
357544000382	transmembrane helices; other site
357544000383	Heme-copper oxidase subunit I.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which catalyze the reduction of O2 and simultaneously pump protons across the membrane.  The superfamily is...; Region: Heme_Cu_Oxidase_I; cl00275
357544000384	Low-spin heme binding site [chemical binding]; other site
357544000385	Cytochrome C and Quinol oxidase polypeptide I; Region: COX1; pfam00115
357544000386	D-pathway; other site
357544000387	Putative water exit pathway; other site
357544000388	Binuclear center (active site) [active]
357544000389	K-pathway; other site
357544000390	Putative proton exit pathway; other site
357544000391	Cbb3-type cytochrome oxidase, cytochrome c subunit [Energy production and conversion]; Region: CcoO; COG2993
357544000392	Cytochrome C oxidase, mono-heme subunit/FixO; Region: FixO; cl01130
357544000393	cytochrome c oxidase, cbb3-type, CcoQ subunit, epsilon-Proteobacterial; Region: cbb3_Q_epsi; TIGR02736
357544000394	cytochrome c oxidase, cbb3-type, subunit III; Region: ccoP; TIGR00782
357544000395	Cytochrome c; Region: Cytochrom_C; pfam00034
357544000396	Cytochrome c; Region: Cytochrom_C; pfam00034
357544000397	Family of unknown function (DUF4006); Region: DUF4006; pfam13179
357544000398	Predicted periplasmic solute-binding protein [General function prediction only]; Region: COG2107
357544000399	recombinase A; Provisional; Region: recA; PRK09354
357544000400	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
357544000401	hexamer interface [polypeptide binding]; other site
357544000402	Walker A motif; other site
357544000403	ATP binding site [chemical binding]; other site
357544000404	Walker B motif; other site
357544000405	enolase; Provisional; Region: eno; PRK00077
357544000406	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
357544000407	dimer interface [polypeptide binding]; other site
357544000408	metal binding site [ion binding]; metal-binding site
357544000409	substrate binding pocket [chemical binding]; other site
357544000410	AMIN domain; Region: AMIN; pfam11741
357544000411	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
357544000412	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
357544000413	ADP binding site [chemical binding]; other site
357544000414	magnesium binding site [ion binding]; other site
357544000415	putative shikimate binding site; other site
357544000416	Cache domain; Region: Cache_1; pfam02743
357544000417	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
357544000418	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
357544000419	Ligand binding site; other site
357544000420	metal-binding site
357544000421	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
357544000422	Sel1-like repeats; Region: SEL1; smart00671
357544000423	Sel1-like repeats; Region: SEL1; smart00671
357544000424	Sel1-like repeats; Region: SEL1; smart00671
357544000425	Sel1-like repeats; Region: SEL1; smart00671
357544000426	Sel1-like repeats; Region: SEL1; smart00671
357544000427	Sel1-like repeats; Region: SEL1; smart00671
357544000428	hypothetical protein; Provisional; Region: PRK12378
357544000429	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
357544000430	dimer interface [polypeptide binding]; other site
357544000431	active site
357544000432	Schiff base residues; other site
357544000433	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
357544000434	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; Region: HAMP; smart00304
357544000435	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
357544000436	dimer interface [polypeptide binding]; other site
357544000437	phosphorylation site [posttranslational modification]
357544000438	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
357544000439	ATP binding site [chemical binding]; other site
357544000440	Mg2+ binding site [ion binding]; other site
357544000441	G-X-G motif; other site
357544000442	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
357544000443	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
357544000444	active site
357544000445	phosphorylation site [posttranslational modification]
357544000446	intermolecular recognition site; other site
357544000447	dimerization interface [polypeptide binding]; other site
357544000448	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
357544000449	DNA binding site [nucleotide binding]
357544000450	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
357544000451	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
357544000452	Peptidase family U32; Region: Peptidase_U32; pfam01136
357544000453	peptide chain release factor 2; Region: prfB; TIGR00020
357544000454	This domain is found in peptide chain release factors; Region: PCRF; smart00937
357544000455	RF-1 domain; Region: RF-1; pfam00472
357544000456	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
357544000457	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
357544000458	dimer interface [polypeptide binding]; other site
357544000459	putative functional site; other site
357544000460	putative MPT binding site; other site
357544000461	Flagellar biosynthesis pathway, component FliR [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliR; COG1684
357544000462	Etoposide-induced protein 2.4 (EI24); Region: EI24; pfam07264
357544000463	peptidylprolyl isomerase; Provisional; Region: prsA; PRK00059
357544000464	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
357544000465	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
357544000466	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
357544000467	intersubunit interface [polypeptide binding]; other site
357544000468	active site
357544000469	zinc binding site [ion binding]; other site
357544000470	Na+ binding site [ion binding]; other site
357544000471	elongation factor P; Validated; Region: PRK00529
357544000472	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
357544000473	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
357544000474	RNA binding site [nucleotide binding]; other site
357544000475	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
357544000476	RNA binding site [nucleotide binding]; other site
357544000477	pseudaminic acid synthase; Region: PseI; TIGR03586
357544000478	NeuB family; Region: NeuB; pfam03102
357544000479	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
357544000480	NeuB binding interface [polypeptide binding]; other site
357544000481	putative substrate binding site [chemical binding]; other site
357544000482	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
357544000483	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
357544000484	Walker A/P-loop; other site
357544000485	ATP binding site [chemical binding]; other site
357544000486	Q-loop/lid; other site
357544000487	ABC transporter signature motif; other site
357544000488	Walker B; other site
357544000489	D-loop; other site
357544000490	H-loop/switch region; other site
357544000491	apolipoprotein N-acyltransferase; Reviewed; Region: PRK12291
357544000492	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
357544000493	active site
357544000494	catalytic triad [active]
357544000495	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
357544000496	Colicin V production protein; Region: Colicin_V; pfam02674
357544000497	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
357544000498	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
357544000499	dimer interface [polypeptide binding]; other site
357544000500	putative anticodon binding site; other site
357544000501	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
357544000502	motif 1; other site
357544000503	active site
357544000504	motif 2; other site
357544000505	motif 3; other site
357544000506	serine hydroxymethyltransferase; Reviewed; Region: PRK13034
357544000507	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
357544000508	dimer interface [polypeptide binding]; other site
357544000509	active site
357544000510	glycine-pyridoxal phosphate binding site [chemical binding]; other site
357544000511	folate binding site [chemical binding]; other site
357544000512	Domain of unknown function (DUF1882); Region: DUF1882; pfam08966
357544000513	AE_Prim_S_like: primase domain similar to that found in the small subunit of archaeal and eukaryotic (A/E) DNA primases. The replication machineries of A/Es are distinct from that of bacteria. Primases are DNA-dependent RNA polymerases which synthesis...; Region: AE_Prim_S_like; cl01287
357544000514	Uncharacterized protein family, UPF0114; Region: UPF0114; cl01078
357544000515	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
357544000516	putative active site [active]
357544000517	catalytic site [active]
357544000518	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
357544000519	PLD-like domain; Region: PLDc_2; pfam13091
357544000520	putative active site [active]
357544000521	catalytic site [active]
357544000522	fumarate reductase iron-sulfur subunit; Provisional; Region: frdB; PRK13552
357544000523	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
357544000524	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
357544000525	fumarate reductase flavoprotein subunit; Provisional; Region: PRK08626
357544000526	L-aspartate oxidase; Provisional; Region: PRK06175
357544000527	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
357544000528	fumarate reductase cytochrome b-556 subunit; Provisional; Region: PRK13553
357544000529	Quinol:fumarate reductase (QFR) Type B subfamily, transmembrane subunit;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinone...; Region: QFR_TypeB_TM; cd00581
357544000530	Iron-sulfur protein interface; other site
357544000531	proximal heme binding site [chemical binding]; other site
357544000532	distal heme binding site [chemical binding]; other site
357544000533	dimer interface [polypeptide binding]; other site
357544000534	triosephosphate isomerase; Provisional; Region: PRK14567
357544000535	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
357544000536	substrate binding site [chemical binding]; other site
357544000537	dimer interface [polypeptide binding]; other site
357544000538	catalytic triad [active]
357544000539	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK08415
357544000540	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
357544000541	NAD binding site [chemical binding]; other site
357544000542	homotetramer interface [polypeptide binding]; other site
357544000543	homodimer interface [polypeptide binding]; other site
357544000544	substrate binding site [chemical binding]; other site
357544000545	active site
357544000546	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Region: lipid_A_lpxD; TIGR01853
357544000547	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
357544000548	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
357544000549	trimer interface [polypeptide binding]; other site
357544000550	active site
357544000551	UDP-GlcNAc binding site [chemical binding]; other site
357544000552	lipid binding site [chemical binding]; lipid-binding site
357544000553	S-adenosylmethionine synthetase; Validated; Region: PRK05250
357544000554	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
357544000555	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
357544000556	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
357544000557	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
357544000558	active site
357544000559	multimer interface [polypeptide binding]; other site
357544000560	Ribosomal protein L32 [Translation, ribosomal structure and biogenesis]; Region: RpmF; COG0333
357544000561	fatty acid/phospholipid synthesis protein PlsX; Region: plsX; TIGR00182
357544000562	3-oxoacyl-(acyl-carrier-protein) synthase III; Region: fabH; TIGR00747
357544000563	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
357544000564	dimer interface [polypeptide binding]; other site
357544000565	active site
357544000566	CoA binding pocket [chemical binding]; other site
357544000567	AAA domain; Region: AAA_21; pfam13304
357544000568	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
357544000569	Walker B; other site
357544000570	D-loop; other site
357544000571	H-loop/switch region; other site
357544000572	AAA ATPase domain; Region: AAA_15; pfam13175
357544000573	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
357544000574	Probable transposase; Region: OrfB_IS605; pfam01385
357544000575	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
357544000576	Predicted site-specific integrase-resolvase [DNA replication, recombination, and repair]; Region: COG2452
357544000577	Helix-Turn-Helix DNA binding domain of truncated MerR-like proteins; Region: HTH_MerR-trunc; cd04762
357544000578	DNA binding residues [nucleotide binding]
357544000579	Serine Recombinase (SR) family, IS607-like transposase subfamily, catalytic domain; members contain a DNA binding domain with homology to MerR/SoxR located N-terminal to the catalytic domain. Serine recombinases catalyze site-specific recombination of...; Region: SR_IS607_transposase_like; cd03769
357544000580	catalytic residues [active]
357544000581	catalytic nucleophile [active]
357544000582	Predicted RNA binding protein (dsRBD-like fold), HicA family    [General function prediction only]; Region: COG1724
357544000583	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: COG1598
357544000584	antiporter inner membrane protein; Provisional; Region: PRK11670
357544000585	Domain of unknown function DUF59; Region: DUF59; pfam01883
357544000586	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
357544000587	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
357544000588	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
357544000589	active site
357544000590	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
357544000591	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
357544000592	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
357544000593	heat shock protein 90; Provisional; Region: PRK05218
357544000594	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
357544000595	ATP binding site [chemical binding]; other site
357544000596	Mg2+ binding site [ion binding]; other site
357544000597	G-X-G motif; other site
357544000598	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
357544000599	Sel1-like repeats; Region: SEL1; smart00671
357544000600	Sel1-like repeats; Region: SEL1; smart00671
357544000601	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
357544000602	TPR motif; other site
357544000603	binding surface
357544000604	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
357544000605	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
357544000606	metal binding site [ion binding]; metal-binding site
357544000607	dimer interface [polypeptide binding]; other site
357544000608	glucose-inhibited division protein A; Region: gidA; TIGR00136
357544000609	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
357544000610	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
357544000611	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
357544000612	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
357544000613	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
357544000614	transmembrane helices; other site
357544000615	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
357544000616	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
357544000617	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: Dxr; TIGR00243
357544000618	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
357544000619	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
357544000620	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
357544000621	Beta-1,4-N-acetylgalactosaminyltransferase (CgtA); Region: CgtA; pfam06306
357544000622	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
357544000623	substrate binding site [chemical binding]; other site
357544000624	Helix-turn-helix domain; Region: HTH_28; pfam13518
357544000625	cysteine desulfurase, NifS family, epsilon proteobacteria type; Region: nifS_epsilon; TIGR03403
357544000626	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
357544000627	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
357544000628	catalytic residue [active]
357544000629	Fe-S cluster assembly protein NifU; Region: NifU_proper; TIGR02000
357544000630	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
357544000631	trimerization site [polypeptide binding]; other site
357544000632	active site
357544000633	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
357544000634	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
357544000635	DNA repair protein RadA; Region: sms; TIGR00416
357544000636	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
357544000637	Walker A motif/ATP binding site; other site
357544000638	ATP binding site [chemical binding]; other site
357544000639	Walker B motif; other site
357544000640	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
357544000641	Peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: MsrA; COG0225
357544000642	Conserved domain frequently associated with peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: COG0229
357544000643	SelR domain; Region: SelR; pfam01641
357544000644	Predicted permeases [General function prediction only]; Region: COG0730
357544000645	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544000646	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
357544000647	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
357544000648	Sulfate transporter family; Region: Sulfate_transp; pfam00916
357544000649	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544000650	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
357544000651	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
357544000652	Ligand binding site; other site
357544000653	oligomer interface; other site
357544000654	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
357544000655	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
357544000656	hypothetical protein; Provisional; Region: PRK04081
357544000657	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
357544000658	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
357544000659	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
357544000660	binding surface
357544000661	TPR motif; other site
357544000662	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
357544000663	binding surface
357544000664	TPR motif; other site
357544000665	Sel1-like repeats; Region: SEL1; smart00671
357544000666	Sel1-like repeats; Region: SEL1; smart00671
357544000667	Cytochrome c; Region: Cytochrom_C; cl11414
357544000668	Porphobilinogen deaminase [Coenzyme metabolism]; Region: HemC; COG0181
357544000669	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
357544000670	domain interfaces; other site
357544000671	active site
357544000672	prolyl-tRNA synthetase, family II; Region: proS_fam_II; TIGR00409
357544000673	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
357544000674	dimer interface [polypeptide binding]; other site
357544000675	motif 1; other site
357544000676	active site
357544000677	motif 2; other site
357544000678	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
357544000679	putative deacylase active site [active]
357544000680	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
357544000681	active site
357544000682	motif 3; other site
357544000683	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
357544000684	anticodon binding site; other site
357544000685	glutamyl-tRNA reductase; Region: hemA; TIGR01035
357544000686	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
357544000687	tRNA; other site
357544000688	putative tRNA binding site [nucleotide binding]; other site
357544000689	putative NADP binding site [chemical binding]; other site
357544000690	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
357544000691	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
357544000692	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
357544000693	substrate binding pocket [chemical binding]; other site
357544000694	chain length determination region; other site
357544000695	substrate-Mg2+ binding site; other site
357544000696	catalytic residues [active]
357544000697	aspartate-rich region 1; other site
357544000698	active site lid residues [active]
357544000699	aspartate-rich region 2; other site
357544000700	Domain of unknown function (DUF2018); Region: DUF2018; pfam09442
357544000701	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
357544000702	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
357544000703	dimerization interface [polypeptide binding]; other site
357544000704	DPS ferroxidase diiron center [ion binding]; other site
357544000705	ion pore; other site
357544000706	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
357544000707	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
357544000708	dimer interface [polypeptide binding]; other site
357544000709	phosphorylation site [posttranslational modification]
357544000710	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
357544000711	ATP binding site [chemical binding]; other site
357544000712	Mg2+ binding site [ion binding]; other site
357544000713	G-X-G motif; other site
357544000714	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
357544000715	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
357544000716	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
357544000717	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
357544000718	ATP binding site [chemical binding]; other site
357544000719	Mg++ binding site [ion binding]; other site
357544000720	motif III; other site
357544000721	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
357544000722	nucleotide binding region [chemical binding]; other site
357544000723	ATP-binding site [chemical binding]; other site
357544000724	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
357544000725	SPFH domain / Band 7 family; Region: Band_7; pfam01145
357544000726	Protein of unknown function (DUF2393); Region: DUF2393; pfam09624
357544000727	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
357544000728	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
357544000729	Walker A/P-loop; other site
357544000730	ATP binding site [chemical binding]; other site
357544000731	Q-loop/lid; other site
357544000732	ABC transporter signature motif; other site
357544000733	Walker B; other site
357544000734	D-loop; other site
357544000735	H-loop/switch region; other site
357544000736	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
357544000737	Walker A/P-loop; other site
357544000738	ATP binding site [chemical binding]; other site
357544000739	Q-loop/lid; other site
357544000740	ABC transporter signature motif; other site
357544000741	Walker B; other site
357544000742	D-loop; other site
357544000743	H-loop/switch region; other site
357544000744	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
357544000745	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4239
357544000746	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
357544000747	dimer interface [polypeptide binding]; other site
357544000748	conserved gate region; other site
357544000749	putative PBP binding loops; other site
357544000750	ABC-ATPase subunit interface; other site
357544000751	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544000752	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544000753	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
357544000754	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
357544000755	GDP-binding site [chemical binding]; other site
357544000756	ACT binding site; other site
357544000757	IMP binding site; other site
357544000758	Uncharacterized conserved protein [Function unknown]; Region: COG3334
357544000759	RIP metalloprotease RseP; Region: TIGR00054
357544000760	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
357544000761	active site
357544000762	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
357544000763	exodeoxyribonuclease VII, large subunit; Region: xseA; TIGR00237
357544000764	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
357544000765	generic binding surface II; other site
357544000766	generic binding surface I; other site
357544000767	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
357544000768	DNA methylase; Region: N6_N4_Mtase; pfam01555
357544000769	DNA methylase; Region: N6_N4_Mtase; pfam01555
357544000770	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
357544000771	DNA methylase; Region: N6_N4_Mtase; pfam01555
357544000772	Clp amino terminal domain; Region: Clp_N; pfam02861
357544000773	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
357544000774	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
357544000775	Walker A motif; other site
357544000776	ATP binding site [chemical binding]; other site
357544000777	Walker B motif; other site
357544000778	arginine finger; other site
357544000779	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
357544000780	Walker A motif; other site
357544000781	ATP binding site [chemical binding]; other site
357544000782	Walker B motif; other site
357544000783	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
357544000784	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
357544000785	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; pfam02683
357544000786	Dihydroorotase and related cyclic amidohydrolases [Nucleotide transport and metabolism]; Region: PyrC; COG0044
357544000787	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
357544000788	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
357544000789	active site
357544000790	chlorohydrolase; Provisional; Region: PRK08418
357544000791	Metallo-dependent hydrolases, subgroup D is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_D; cd01312
357544000792	active site
357544000793	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
357544000794	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14339
357544000795	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
357544000796	FeS/SAM binding site; other site
357544000797	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: DUF374; Region: LPLAT_DUF374-like; cd07983
357544000798	putative acyl-acceptor binding pocket; other site
357544000799	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
357544000800	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
357544000801	Exopolyphosphatase [Nucleotide transport and metabolism / Inorganic ion transport and metabolism]; Region: GppA; COG0248
357544000802	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
357544000803	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
357544000804	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
357544000805	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
357544000806	putative active site [active]
357544000807	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
357544000808	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
357544000809	putative acyl-acceptor binding pocket; other site
357544000810	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
357544000811	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
357544000812	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3400
357544000813	TrkA-C domain; Region: TrkA_C; pfam02080
357544000814	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
357544000815	active site
357544000816	dimer interface [polypeptide binding]; other site
357544000817	metal binding site [ion binding]; metal-binding site
357544000818	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
357544000819	Mechanosensitive ion channel; Region: MS_channel; pfam00924
357544000820	radical SAM methylthiotransferase, MiaB/RimO family; Region: TIGR00089
357544000821	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
357544000822	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
357544000823	FeS/SAM binding site; other site
357544000824	ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones]; Region: HflB; COG0465
357544000825	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
357544000826	Walker A motif; other site
357544000827	ATP binding site [chemical binding]; other site
357544000828	Walker B motif; other site
357544000829	arginine finger; other site
357544000830	Domain of unknown function (DUF4149); Region: DUF4149; pfam13664
357544000831	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
357544000832	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
357544000833	PPE-repeat proteins [Cell motility and secretion]; Region: COG5651
357544000834	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
357544000835	Autotransporter beta-domain; Region: Autotransporter; pfam03797
357544000836	diaminopimelate decarboxylase; Region: lysA; TIGR01048
357544000837	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
357544000838	active site
357544000839	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
357544000840	substrate binding site [chemical binding]; other site
357544000841	catalytic residues [active]
357544000842	dimer interface [polypeptide binding]; other site
357544000843	Chorismate mutase [Amino acid transport and metabolism]; Region: PheA; COG1605
357544000844	Uncharacterized conserved protein [Function unknown]; Region: COG4866
357544000845	aminodeoxychorismate synthase; Provisional; Region: PRK07508
357544000846	chorismate binding enzyme; Region: Chorismate_bind; cl10555
357544000847	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cl00224
357544000848	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
357544000849	substrate-cofactor binding pocket; other site
357544000850	pyridoxal 5'-phosphate binding site [chemical binding]; other site
357544000851	catalytic residue [active]
357544000852	acylamide amidohydrolase; Provisional; Region: amiE; PRK13286
357544000853	aliphatic amidases (class 2 nitrilases); Region: aliphatic_amidase; cd07565
357544000854	multimer interface [polypeptide binding]; other site
357544000855	active site
357544000856	catalytic triad [active]
357544000857	dimer interface [polypeptide binding]; other site
357544000858	flagellar hook-associated protein FlgL; Validated; Region: flgL; PRK08412
357544000859	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
357544000860	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
357544000861	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
357544000862	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
357544000863	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
357544000864	peptide binding site [polypeptide binding]; other site
357544000865	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
357544000866	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
357544000867	dimer interface [polypeptide binding]; other site
357544000868	conserved gate region; other site
357544000869	putative PBP binding loops; other site
357544000870	ABC-ATPase subunit interface; other site
357544000871	dipeptide transporter; Provisional; Region: PRK10913
357544000872	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
357544000873	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
357544000874	dimer interface [polypeptide binding]; other site
357544000875	conserved gate region; other site
357544000876	putative PBP binding loops; other site
357544000877	ABC-ATPase subunit interface; other site
357544000878	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
357544000879	nickel import ATP-binding protein NikD; Region: nickel_nikD; TIGR02770
357544000880	Walker A/P-loop; other site
357544000881	ATP binding site [chemical binding]; other site
357544000882	Q-loop/lid; other site
357544000883	ABC transporter signature motif; other site
357544000884	Walker B; other site
357544000885	D-loop; other site
357544000886	H-loop/switch region; other site
357544000887	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
357544000888	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
357544000889	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
357544000890	Walker A/P-loop; other site
357544000891	ATP binding site [chemical binding]; other site
357544000892	Q-loop/lid; other site
357544000893	ABC transporter signature motif; other site
357544000894	Walker B; other site
357544000895	D-loop; other site
357544000896	H-loop/switch region; other site
357544000897	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
357544000898	GTPase CgtA; Reviewed; Region: obgE; PRK12299
357544000899	GTP1/OBG; Region: GTP1_OBG; pfam01018
357544000900	Obg GTPase; Region: Obg; cd01898
357544000901	G1 box; other site
357544000902	GTP/Mg2+ binding site [chemical binding]; other site
357544000903	Switch I region; other site
357544000904	G2 box; other site
357544000905	G3 box; other site
357544000906	Switch II region; other site
357544000907	G4 box; other site
357544000908	G5 box; other site
357544000909	Alginate lyase; Region: Alginate_lyase; pfam05426
357544000910	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
357544000911	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
357544000912	inhibitor-cofactor binding pocket; inhibition site
357544000913	pyridoxal 5'-phosphate binding site [chemical binding]; other site
357544000914	catalytic residue [active]
357544000915	Putative F0F1-ATPase subunit (ATPase_gene1); Region: ATPase_gene1; pfam09527
357544000916	Predicted amidohydrolase [General function prediction only]; Region: COG0388
357544000917	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cd07197
357544000918	active site
357544000919	catalytic triad [active]
357544000920	dimer interface [polypeptide binding]; other site
357544000921	Catalytic domain of Helicobacter pylori peptidoglycan deacetylase (HpPgdA) and similar proteins; Region: CE4_HpPgdA_like; cd10938
357544000922	active site
357544000923	catalytic site [active]
357544000924	Zn binding site [ion binding]; other site
357544000925	tetramer interface [polypeptide binding]; other site
357544000926	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
357544000927	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
357544000928	DNA methylase; Region: N6_N4_Mtase; pfam01555
357544000929	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
357544000930	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
357544000931	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
357544000932	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
357544000933	Major Facilitator Superfamily; Region: MFS_1; pfam07690
357544000934	putative substrate translocation pore; other site
357544000935	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544000936	heme oxygenase, HugZ family; Region: heme_ox_HugZ; TIGR04109
357544000937	Protein of unknown function (DUF2470); Region: DUF2470; pfam10615
357544000938	Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381
357544000939	Arginyl tRNA synthetase N terminal domain; Region: Arg_tRNA_synt_N; pfam03485
357544000940	arginyl-tRNA synthetase; Region: argS; TIGR00456
357544000941	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
357544000942	active site
357544000943	HIGH motif; other site
357544000944	KMSK motif region; other site
357544000945	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
357544000946	tRNA binding surface [nucleotide binding]; other site
357544000947	anticodon binding site; other site
357544000948	mttA/Hcf106 family; Region: MttA_Hcf106; cl00788
357544000949	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
357544000950	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
357544000951	catalytic site [active]
357544000952	G-X2-G-X-G-K; other site
357544000953	Catalytic domain of EDTA-resistant nuclease Nuc, vertebrate phospholipase D6, and similar proteins; Region: PLDc_Nuc_like; cd09116
357544000954	PLD-like domain; Region: PLDc_2; pfam13091
357544000955	putative active site [active]
357544000956	catalytic site [active]
357544000957	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544000958	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
357544000959	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
357544000960	CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513
357544000961	ligand binding site; other site
357544000962	tetramer interface; other site
357544000963	Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: spsG; COG3980
357544000964	pseudaminic acid biosynthesis N-acetyl transferase; Region: PseH; TIGR03585
357544000965	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
357544000966	Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663
357544000967	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
357544000968	NAD synthetase; Provisional; Region: PRK13980
357544000969	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
357544000970	homodimer interface [polypeptide binding]; other site
357544000971	NAD binding pocket [chemical binding]; other site
357544000972	ATP binding pocket [chemical binding]; other site
357544000973	Mg binding site [ion binding]; other site
357544000974	active-site loop [active]
357544000975	ketol-acid reductoisomerase; Provisional; Region: PRK05479
357544000976	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
357544000977	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
357544000978	Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning]; Region: MinD; COG2894
357544000979	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
357544000980	Switch I; other site
357544000981	Switch II; other site
357544000982	cell division topological specificity factor MinE; Region: minE; TIGR01215
357544000983	DNA protecting protein DprA; Region: dprA; TIGR00732
357544000984	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758
357544000985	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
357544000986	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
357544000987	Sel1-like repeats; Region: SEL1; smart00671
357544000988	Sel1-like repeats; Region: SEL1; smart00671
357544000989	Sel1-like repeats; Region: SEL1; smart00671
357544000990	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
357544000991	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
357544000992	active site
357544000993	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
357544000994	DHH family; Region: DHH; pfam01368
357544000995	DHHA1 domain; Region: DHHA1; pfam02272
357544000996	CTP synthetase; Validated; Region: pyrG; PRK05380
357544000997	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
357544000998	Catalytic site [active]
357544000999	active site
357544001000	UTP binding site [chemical binding]; other site
357544001001	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
357544001002	active site
357544001003	putative oxyanion hole; other site
357544001004	catalytic triad [active]
357544001005	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474
357544001006	flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF); Region: fliF; TIGR00206
357544001007	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
357544001008	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
357544001009	flagellar motor switch protein FliG; Region: fliG; TIGR00207
357544001010	FliG C-terminal domain; Region: FliG_C; pfam01706
357544001011	flagellar assembly protein H; Validated; Region: fliH; PRK06669
357544001012	Flagellar assembly protein FliH; Region: FliH; pfam02108
357544001013	1-deoxy-D-xylulose-5-phosphate synthase; Region: dxs; TIGR00204
357544001014	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
357544001015	TPP-binding site; other site
357544001016	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
357544001017	PYR/PP interface [polypeptide binding]; other site
357544001018	dimer interface [polypeptide binding]; other site
357544001019	TPP binding site [chemical binding]; other site
357544001020	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
357544001021	GTP-binding protein LepA; Provisional; Region: PRK05433
357544001022	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
357544001023	G1 box; other site
357544001024	putative GEF interaction site [polypeptide binding]; other site
357544001025	GTP/Mg2+ binding site [chemical binding]; other site
357544001026	Switch I region; other site
357544001027	G2 box; other site
357544001028	G3 box; other site
357544001029	Switch II region; other site
357544001030	G4 box; other site
357544001031	G5 box; other site
357544001032	Translation_Factor_II_like: Elongation factor Tu (EF-Tu) domain II-like proteins. Elongation factor Tu consists of three structural domains, this family represents the second domain. Domain II adopts a beta barrel structure and is involved in binding to...; Region: Translation_Factor_II_like; cl02787
357544001033	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
357544001034	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
357544001035	Domain of unknown function (DUF3883); Region: DUF3883; pfam13020
357544001036	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgG; COG4786
357544001037	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
357544001038	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
357544001039	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
357544001040	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
357544001041	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
357544001042	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
357544001043	Inactivated superfamily I helicase [DNA replication, recombination, and repair]; Region: COG3893
357544001044	RecB family exonuclease [DNA replication, recombination, and repair]; Region: COG2887
357544001045	transketolase, bacterial and yeast; Region: tktlase_bact; TIGR00232
357544001046	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
357544001047	TPP-binding site [chemical binding]; other site
357544001048	dimer interface [polypeptide binding]; other site
357544001049	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
357544001050	PYR/PP interface [polypeptide binding]; other site
357544001051	dimer interface [polypeptide binding]; other site
357544001052	TPP binding site [chemical binding]; other site
357544001053	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
357544001054	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
357544001055	riboflavin kinase/FMN adenylyltransferase; Region: ribF; TIGR00083
357544001056	active site
357544001057	Riboflavin kinase; Region: Flavokinase; smart00904
357544001058	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
357544001059	hemolysin TlyA family protein; Region: tly; TIGR00478
357544001060	RNA binding surface [nucleotide binding]; other site
357544001061	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
357544001062	S-adenosylmethionine binding site [chemical binding]; other site
357544001063	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
357544001064	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
357544001065	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
357544001066	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
357544001067	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
357544001068	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
357544001069	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
357544001070	Walker A/P-loop; other site
357544001071	ATP binding site [chemical binding]; other site
357544001072	Q-loop/lid; other site
357544001073	ABC transporter signature motif; other site
357544001074	Walker B; other site
357544001075	D-loop; other site
357544001076	H-loop/switch region; other site
357544001077	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
357544001078	Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes [Defense mechanisms]; Region: COG1787
357544001079	Restriction endonuclease; Region: Mrr_cat; pfam04471
357544001080	Predicted ATPases [General function prediction only]; Region: COG1106
357544001081	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
357544001082	Walker A/P-loop; other site
357544001083	ATP binding site [chemical binding]; other site
357544001084	High-affinity nickel permease [Inorganic ion transport and metabolism]; Region: HoxN; COG3376
357544001085	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cd00596
357544001086	active site
357544001087	Zn binding site [ion binding]; other site
357544001088	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
357544001089	metal-binding site [ion binding]
357544001090	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
357544001091	metal-binding site [ion binding]
357544001092	copper-(or silver)-translocating P-type ATPase; Region: ATPase-IB1_Cu; TIGR01511
357544001093	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
357544001094	Soluble P-type ATPase [General function prediction only]; Region: COG4087
357544001095	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
357544001096	CDP-diacylglycerol--serine O-phosphatidyltransferase; Region: pssA; TIGR00473
357544001097	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
357544001098	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
357544001099	Walker A motif; other site
357544001100	ATP binding site [chemical binding]; other site
357544001101	Walker B motif; other site
357544001102	arginine finger; other site
357544001103	Peptidase family M41; Region: Peptidase_M41; pfam01434
357544001104	ribosomal protein L11 methyltransferase; Region: prmA; TIGR00406
357544001105	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
357544001106	S-adenosylmethionine binding site [chemical binding]; other site
357544001107	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
357544001108	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
357544001109	active site
357544001110	phosphorylation site [posttranslational modification]
357544001111	intermolecular recognition site; other site
357544001112	dimerization interface [polypeptide binding]; other site
357544001113	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544001114	rRNA small subunit methyltransferase G; Region: GidB; pfam02527
357544001115	16S rRNA (guanine(527)-N(7))-methyltransferase GidB; Region: gidB; TIGR00138
357544001116	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
357544001117	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
357544001118	Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion]; Region: TatC; COG0805
357544001119	sec-independent translocase; Provisional; Region: PRK04098
357544001120	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
357544001121	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
357544001122	Walker A motif; other site
357544001123	ATP binding site [chemical binding]; other site
357544001124	Walker B motif; other site
357544001125	arginine finger; other site
357544001126	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
357544001127	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
357544001128	oligomerization interface [polypeptide binding]; other site
357544001129	active site
357544001130	metal binding site [ion binding]; metal-binding site
357544001131	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544001132	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544001133	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
357544001134	septum formation inhibitor; Reviewed; Region: minC; PRK00556
357544001135	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
357544001136	UDP-3-0-acyl N-acetylglucosamine deacetylase; Region: lpxC; TIGR00325
357544001137	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
357544001138	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
357544001139	homoserine kinase; Region: thrB; TIGR00191
357544001140	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
357544001141	Predicted nucleic-acid-binding protein implicated in transcription termination [Transcription]; Region: COG2740
357544001142	putative RNA binding cleft [nucleotide binding]; other site
357544001143	translation initiation factor IF-2; Region: IF-2; TIGR00487
357544001144	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
357544001145	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
357544001146	G1 box; other site
357544001147	putative GEF interaction site [polypeptide binding]; other site
357544001148	GTP/Mg2+ binding site [chemical binding]; other site
357544001149	Switch I region; other site
357544001150	G2 box; other site
357544001151	G3 box; other site
357544001152	Switch II region; other site
357544001153	G4 box; other site
357544001154	G5 box; other site
357544001155	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
357544001156	Translation-initiation factor 2; Region: IF-2; pfam11987
357544001157	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
357544001158	Ribosome-binding factor A; Region: RBFA; cl00542
357544001159	Uncharacterized BCR, YhbC family COG0779; Region: DUF150; pfam02576
357544001160	Sm and related proteins; Region: Sm_like; cl00259
357544001161	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
357544001162	putative oligomer interface [polypeptide binding]; other site
357544001163	putative RNA binding site [nucleotide binding]; other site
357544001164	acetyl-CoA synthetase; Provisional; Region: PRK00174
357544001165	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
357544001166	active site
357544001167	CoA binding site [chemical binding]; other site
357544001168	acyl-activating enzyme (AAE) consensus motif; other site
357544001169	AMP binding site [chemical binding]; other site
357544001170	acetate binding site [chemical binding]; other site
357544001171	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
357544001172	putative active site [active]
357544001173	putative metal binding site [ion binding]; other site
357544001174	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
357544001175	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
357544001176	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
357544001177	active site
357544001178	intermolecular recognition site; other site
357544001179	dimerization interface [polypeptide binding]; other site
357544001180	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
357544001181	DNA binding site [nucleotide binding]
357544001182	Predicted phosphohydrolase (DHH superfamily) [General function prediction only]; Region: COG2404
357544001183	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
357544001184	FHIPEP family; Region: FHIPEP; pfam00771
357544001185	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
357544001186	16S/18S rRNA binding site [nucleotide binding]; other site
357544001187	S13e-L30e interaction site [polypeptide binding]; other site
357544001188	25S rRNA binding site [nucleotide binding]; other site
357544001189	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
357544001190	O-Antigen ligase; Region: Wzy_C; pfam04932
357544001191	Dehydroquinase class II; Region: DHquinase_II; pfam01220
357544001192	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
357544001193	trimer interface [polypeptide binding]; other site
357544001194	active site
357544001195	dimer interface [polypeptide binding]; other site
357544001196	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
357544001197	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
357544001198	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
357544001199	active site
357544001200	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
357544001201	catalytic center binding site [active]
357544001202	ATP binding site [chemical binding]; other site
357544001203	flagellar biosynthesis regulator FlhF; Validated; Region: flhF; PRK05703
357544001204	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
357544001205	Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]; Region: flhG; COG0455
357544001206	FleN is a member of the Fer4_NifH superfamily. It shares the common function as an ATPase, with the ATP-binding domain at the N-terminus. In Pseudomonas aeruginosa, FleN gene is involved in regulating the number of flagella and chemotactic motility by...; Region: FleN-like; cd02038
357544001207	P-loop; other site
357544001208	FleN is a member of the Fer4_NifH superfamily. It shares the common function as an ATPase, with the ATP-binding domain at the N-terminus. In Pseudomonas aeruginosa, FleN gene is involved in regulating the number of flagella and chemotactic motility by...; Region: FleN-like; cd02038
357544001209	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
357544001210	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
357544001211	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
357544001212	DNA binding residues [nucleotide binding]
357544001213	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
357544001214	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
357544001215	flagellar motor switch protein FliY; Validated; Region: PRK08432
357544001216	flagellar motor switch protein FliN; Region: fliN; TIGR02480
357544001217	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
357544001218	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4731
357544001219	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
357544001220	metal binding site 2 [ion binding]; metal-binding site
357544001221	putative DNA binding helix; other site
357544001222	metal binding site 1 [ion binding]; metal-binding site
357544001223	dimer interface [polypeptide binding]; other site
357544001224	structural Zn2+ binding site [ion binding]; other site
357544001225	ATPase related to the helicase subunit of the Holliday junction resolvase [DNA replication, recombination, and repair]; Region: MGS1; COG2256
357544001226	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
357544001227	Walker A motif; other site
357544001228	ATP binding site [chemical binding]; other site
357544001229	Walker B motif; other site
357544001230	arginine finger; other site
357544001231	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
357544001232	Helix-Turn-Helix DNA binding domain of the HspR transcription regulator; Region: HTH_HspR; cd04766
357544001233	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
357544001234	DNA binding residues [nucleotide binding]
357544001235	putative dimer interface [polypeptide binding]; other site
357544001236	chaperone protein DnaJ; Provisional; Region: PRK14299
357544001237	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
357544001238	HSP70 interaction site [polypeptide binding]; other site
357544001239	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
357544001240	substrate binding site [polypeptide binding]; other site
357544001241	dimer interface [polypeptide binding]; other site
357544001242	5'-3' exonuclease; Provisional; Region: PRK14976
357544001243	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
357544001244	putative active site [active]
357544001245	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
357544001246	putative DNA binding site [nucleotide binding]; other site
357544001247	putative metal binding site [ion binding]; other site
357544001248	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
357544001249	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
357544001250	active site
357544001251	dimerization interface [polypeptide binding]; other site
357544001252	bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein; Provisional; Region: ispDF; PRK09382
357544001253	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
357544001254	substrate binding site; other site
357544001255	dimer interface; other site
357544001256	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
357544001257	homotrimer interaction site [polypeptide binding]; other site
357544001258	zinc binding site [ion binding]; other site
357544001259	CDP-binding sites; other site
357544001260	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
357544001261	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
357544001262	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
357544001263	protein binding site [polypeptide binding]; other site
357544001264	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
357544001265	protein binding site [polypeptide binding]; other site
357544001266	S-methylmethionine transporter; Provisional; Region: PRK11387
357544001267	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Region: pgsA; TIGR00560
357544001268	7-alpha-hydroxysteroid dehydrogenase; Provisional; Region: PRK08416
357544001269	1-cyclohexenylcarbonyl_coenzyme A_reductase (ChcA)_like, classical (c) SDRs; Region: ChcA_like_SDR_c; cd05359
357544001270	putative NAD(P) binding site [chemical binding]; other site
357544001271	active site
357544001272	dihydrodipicolinate synthase; Region: dapA; TIGR00674
357544001273	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
357544001274	dimer interface [polypeptide binding]; other site
357544001275	active site
357544001276	catalytic residue [active]
357544001277	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
357544001278	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
357544001279	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
357544001280	dihydroorotate dehydrogenase, subfamily 2; Region: pyrD_sub2; TIGR01036
357544001281	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
357544001282	quinone interaction residues [chemical binding]; other site
357544001283	active site
357544001284	catalytic residues [active]
357544001285	FMN binding site [chemical binding]; other site
357544001286	substrate binding site [chemical binding]; other site
357544001287	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
357544001288	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
357544001289	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
357544001290	Catalytic C-terminal domain, first repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C1_like; cd09165
357544001291	putative domain interface [polypeptide binding]; other site
357544001292	putative active site [active]
357544001293	catalytic site [active]
357544001294	Catalytic C-terminal domain, second repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C2_like; cd09168
357544001295	putative active site [active]
357544001296	putative domain interface [polypeptide binding]; other site
357544001297	catalytic site [active]
357544001298	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
357544001299	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
357544001300	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
357544001301	Methyltransferase domain; Region: Methyltransf_26; pfam13659
357544001302	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
357544001303	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
357544001304	Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396
357544001305	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
357544001306	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
357544001307	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
357544001308	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2604
357544001309	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
357544001310	putative metal binding site [ion binding]; other site
357544001311	Heterodisulfide reductase, subunit B [Energy production and conversion]; Region: HdrB; COG2048
357544001312	oligoendopeptidase, pepF/M3 family; Region: M3_fam_3; TIGR02290
357544001313	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_5; cd09610
357544001314	active site
357544001315	Zn binding site [ion binding]; other site
357544001316	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
357544001317	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
357544001318	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544001319	ABC-type molybdate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: ModA; COG0725
357544001320	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
357544001321	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
357544001322	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
357544001323	dimer interface [polypeptide binding]; other site
357544001324	conserved gate region; other site
357544001325	putative PBP binding loops; other site
357544001326	ABC-ATPase subunit interface; other site
357544001327	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
357544001328	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
357544001329	Walker A/P-loop; other site
357544001330	ATP binding site [chemical binding]; other site
357544001331	Q-loop/lid; other site
357544001332	ABC transporter signature motif; other site
357544001333	Walker B; other site
357544001334	D-loop; other site
357544001335	H-loop/switch region; other site
357544001336	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
357544001337	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
357544001338	active site
357544001339	HIGH motif; other site
357544001340	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
357544001341	active site
357544001342	KMSKS motif; other site
357544001343	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544001344	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827
357544001345	Methyltransferase domain; Region: Methyltransf_26; pfam13659
357544001346	TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950
357544001347	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
357544001348	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
357544001349	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
357544001350	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
357544001351	G1 box; other site
357544001352	putative GEF interaction site [polypeptide binding]; other site
357544001353	GTP/Mg2+ binding site [chemical binding]; other site
357544001354	Switch I region; other site
357544001355	G2 box; other site
357544001356	G3 box; other site
357544001357	Switch II region; other site
357544001358	G4 box; other site
357544001359	G5 box; other site
357544001360	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
357544001361	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
357544001362	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dam; COG0338
357544001363	Catalytic GIY-YIG domain of coliphage T4 non-specific endonuclease II, type II restriction endonuclease R.Hpy188I, and similar proteins; Region: GIY-YIG_EndoII_Hpy188I_like; cd10436
357544001364	GIY-YIG motif/motif A; other site
357544001365	DNA binding site [nucleotide binding]
357544001366	active site
357544001367	catalytic site [active]
357544001368	metal binding site [ion binding]; metal-binding site
357544001369	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
357544001370	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
357544001371	cofactor binding site; other site
357544001372	DNA binding site [nucleotide binding]
357544001373	substrate interaction site [chemical binding]; other site
357544001374	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
357544001375	Catalase-like heme-binding proteins similar to the uncharacterized srpA; Region: srpA_like; cd08153
357544001376	putative heme binding pocket [chemical binding]; other site
357544001377	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
357544001378	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
357544001379	Protein of unknown function (DUF3519); Region: DUF3519; pfam12033
357544001380	Protein of unknown function (DUF3519); Region: DUF3519; pfam12033
357544001381	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
357544001382	Cation transport protein; Region: TrkH; cl17365
357544001383	Kef-type K+ transport systems, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: Kch; COG1226
357544001384	TrkA-N domain; Region: TrkA_N; pfam02254
357544001385	TrkA-C domain; Region: TrkA_C; pfam02080
357544001386	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
357544001387	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
357544001388	phospho-N-acetylmuramoyl-pentapeptide-transferase; Region: mraY; TIGR00445
357544001389	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
357544001390	Mg++ binding site [ion binding]; other site
357544001391	putative catalytic motif [active]
357544001392	putative substrate binding site [chemical binding]; other site
357544001393	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03815
357544001394	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
357544001395	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
357544001396	Protein of unknown function (DUF493); Region: DUF493; pfam04359
357544001397	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
357544001398	active site
357544001399	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
357544001400	Na2 binding site [ion binding]; other site
357544001401	putative substrate binding site 1 [chemical binding]; other site
357544001402	Na binding site 1 [ion binding]; other site
357544001403	putative substrate binding site 2 [chemical binding]; other site
357544001404	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
357544001405	Na2 binding site [ion binding]; other site
357544001406	putative substrate binding site 1 [chemical binding]; other site
357544001407	Na binding site 1 [ion binding]; other site
357544001408	putative substrate binding site 2 [chemical binding]; other site
357544001409	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
357544001410	dimerization interface [polypeptide binding]; other site
357544001411	substrate binding site [chemical binding]; other site
357544001412	active site
357544001413	calcium binding site [ion binding]; other site
357544001414	DNA polymerase III, beta subunit; Region: dnan; TIGR00663
357544001415	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
357544001416	putative DNA binding surface [nucleotide binding]; other site
357544001417	dimer interface [polypeptide binding]; other site
357544001418	beta-clamp/translesion DNA polymerase binding surface; other site
357544001419	beta-clamp/clamp loader binding surface; other site
357544001420	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
357544001421	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
357544001422	Mg2+ binding site [ion binding]; other site
357544001423	G-X-G motif; other site
357544001424	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
357544001425	anchoring element; other site
357544001426	dimer interface [polypeptide binding]; other site
357544001427	ATP binding site [chemical binding]; other site
357544001428	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
357544001429	active site
357544001430	putative metal-binding site [ion binding]; other site
357544001431	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
357544001432	R.Pab1 restriction endonuclease; Region: RE_R_Pab1; pfam09522
357544001433	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
357544001434	Peptidase family M23; Region: Peptidase_M23; pfam01551
357544001435	nudix-type nucleoside diphosphatase, YffH/AdpP family; Region: TIGR00052
357544001436	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
357544001437	dimer interface [polypeptide binding]; other site
357544001438	ADP-ribose binding site [chemical binding]; other site
357544001439	active site
357544001440	nudix motif; other site
357544001441	metal binding site [ion binding]; metal-binding site
357544001442	FAD binding domain; Region: FAD_binding_4; pfam01565
357544001443	glycolate oxidase, subunit GlcD; Region: glcD; TIGR00387
357544001444	Protein-interacting Bro1-like domain of mammalian Alix and related domains; Region: BRO1_Alix_like; cl14649
357544001445	dihydrodipicolinate reductase; Region: dapB; TIGR00036
357544001446	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
357544001447	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
357544001448	glutamine synthetase, type I; Region: GlnA; TIGR00653
357544001449	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
357544001450	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
357544001451	Uncharacterized conserved protein [Function unknown]; Region: COG1479
357544001452	Protein of unknown function DUF262; Region: DUF262; pfam03235
357544001453	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
357544001454	Uncharacterized conserved protein [Function unknown]; Region: COG3586
357544001455	ribosomal protein L9; Region: L9; TIGR00158
357544001456	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
357544001457	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
357544001458	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
357544001459	active site
357544001460	HslU subunit interaction site [polypeptide binding]; other site
357544001461	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
357544001462	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
357544001463	Walker A motif; other site
357544001464	ATP binding site [chemical binding]; other site
357544001465	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
357544001466	Walker B motif; other site
357544001467	arginine finger; other site
357544001468	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
357544001469	GTPase [General function prediction only]; Region: Era; COG1159
357544001470	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
357544001471	G1 box; other site
357544001472	GTP/Mg2+ binding site [chemical binding]; other site
357544001473	Switch I region; other site
357544001474	G2 box; other site
357544001475	Switch II region; other site
357544001476	G3 box; other site
357544001477	G4 box; other site
357544001478	G5 box; other site
357544001479	KH domain; Region: KH_2; pfam07650
357544001480	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
357544001481	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
357544001482	Sel1-like repeats; Region: SEL1; smart00671
357544001483	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cl11986
357544001484	domain III; other site
357544001485	Type IV secretory pathway, VirD4 components [Intracellular trafficking and secretion]; Region: VirD4; COG3505
357544001486	The TraG/TraD/VirD4 family are bacterial conjugation proteins involved in type IV secretion. These proteins aid the transfer of DNA from the plasmid into the host bacterial chromosome. They contain an ATP binding domain. VirD4 is involved in DNA transfer...; Region: TraG_VirD4; cd01126
357544001487	Walker A motif; other site
357544001488	ATP binding site [chemical binding]; other site
357544001489	Walker B motif; other site
357544001490	P-type DNA transfer ATPase VirB11; Region: VirB11; TIGR02788
357544001491	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
357544001492	ATP binding site [chemical binding]; other site
357544001493	Walker A motif; other site
357544001494	hexamer interface [polypeptide binding]; other site
357544001495	Walker B motif; other site
357544001496	CagZ; Region: CagZ; pfam09053
357544001497	DC-EC Repeat; Region: CagY_M; pfam07337
357544001498	DC-EC Repeat; Region: CagY_M; pfam07337
357544001499	Type IV secretory pathway, VirB10 components [Intracellular trafficking and secretion]; Region: VirB10; COG2948
357544001500	DC-EC Repeat; Region: CagY_M; pfam07337
357544001501	DC-EC Repeat; Region: CagY_M; pfam07337
357544001502	DC-EC Repeat; Region: CagY_M; pfam07337
357544001503	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cl11423
357544001504	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cl11423
357544001505	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911
357544001506	VirB7 interaction site; other site
357544001507	Niemann-Pick C type protein family; Region: 2A060601; TIGR00917
357544001508	Type IV secretory pathway, component VirB8 [Intracellular trafficking and secretion]; Region: VirB8; COG3736
357544001509	Cag pathogenicity island protein Cag12; Region: Cag12; pfam13117
357544001510	similar to hypothetical protein
357544001511	prolyl-tRNA synthetase; Provisional; Region: PRK08661
357544001512	AAA-like domain; Region: AAA_10; pfam12846
357544001513	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
357544001514	CagA exotoxin; Region: CagA; pfam03507
357544001515	CagA exotoxin; Region: CagA; pfam03507
357544001516	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
357544001517	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
357544001518	glutamate racemase; Region: glut_race; TIGR00067
357544001519	transcription termination factor Rho; Provisional; Region: rho; PRK09376
357544001520	Rho termination factor, N-terminal domain; Region: Rho_N; pfam07498
357544001521	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
357544001522	RNA binding site [nucleotide binding]; other site
357544001523	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
357544001524	multimer interface [polypeptide binding]; other site
357544001525	Walker A motif; other site
357544001526	ATP binding site [chemical binding]; other site
357544001527	Walker B motif; other site
357544001528	Ribosomal protein L31; Region: Ribosomal_L31; pfam01197
357544001529	Predicted methyltransferases [General function prediction only]; Region: COG0313
357544001530	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
357544001531	putative SAM binding site [chemical binding]; other site
357544001532	putative homodimer interface [polypeptide binding]; other site
357544001533	rRNA methylase, putative, group 3; Region: rRNA_methyl_3; TIGR00186
357544001534	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
357544001535	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
357544001536	acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Region: accA; TIGR00513
357544001537	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
357544001538	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK08439
357544001539	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
357544001540	dimer interface [polypeptide binding]; other site
357544001541	active site
357544001542	acyl carrier protein; Provisional; Region: acpP; PRK00982
357544001543	similar to hypothetical protein
357544001544	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
357544001545	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
357544001546	NAD(P) binding site [chemical binding]; other site
357544001547	active site
357544001548	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
357544001549	Predicted membrane protein [Function unknown]; Region: COG3059
357544001550	diaminopimelate epimerase; Region: DapF; TIGR00652
357544001551	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
357544001552	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
357544001553	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
357544001554	Domain of unknown function DUF20; Region: UPF0118; pfam01594
357544001555	Domain of unknown function (DUF4008); Region: DUF4008; pfam13186
357544001556	GTP-binding protein YchF; Reviewed; Region: PRK09601
357544001557	YchF GTPase; Region: YchF; cd01900
357544001558	G1 box; other site
357544001559	GTP/Mg2+ binding site [chemical binding]; other site
357544001560	Switch I region; other site
357544001561	G2 box; other site
357544001562	Switch II region; other site
357544001563	G3 box; other site
357544001564	G4 box; other site
357544001565	G5 box; other site
357544001566	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
357544001567	multifunctional aminopeptidase A; Provisional; Region: PRK00913
357544001568	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
357544001569	interface (dimer of trimers) [polypeptide binding]; other site
357544001570	Substrate-binding/catalytic site; other site
357544001571	Zn-binding sites [ion binding]; other site
357544001572	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
357544001573	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
357544001574	active site
357544001575	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
357544001576	Ribose/Galactose Isomerase; Region: LacAB_rpiB; cl00485
357544001577	Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_1; cd06158
357544001578	Peptidase family M50; Region: Peptidase_M50; pfam02163
357544001579	active site
357544001580	putative substrate binding region [chemical binding]; other site
357544001581	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
357544001582	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
357544001583	Catalytic site [active]
357544001584	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
357544001585	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14191
357544001586	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
357544001587	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
357544001588	homodimer interface [polypeptide binding]; other site
357544001589	NADP binding site [chemical binding]; other site
357544001590	substrate binding site [chemical binding]; other site
357544001591	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
357544001592	Sulfatase; Region: Sulfatase; pfam00884
357544001593	Predicted neuraminidase (sialidase) [Carbohydrate transport and metabolism]; Region: COG4692
357544001594	BNR repeat-like domain; Region: BNR_2; pfam13088
357544001595	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
357544001596	active site
357544001597	substrate binding pocket [chemical binding]; other site
357544001598	dimer interface [polypeptide binding]; other site
357544001599	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
357544001600	TonB family C-terminal domain; Region: tonB_Cterm; TIGR01352
357544001601	flagellar motor switch protein; Validated; Region: PRK08433
357544001602	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
357544001603	endonuclease III; Region: ENDO3c; smart00478
357544001604	minor groove reading motif; other site
357544001605	helix-hairpin-helix signature motif; other site
357544001606	substrate binding pocket [chemical binding]; other site
357544001607	active site
357544001608	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
357544001609	Fe2+ transport system protein A [Inorganic ion transport and metabolism]; Region: FeoA; COG1918
357544001610	Protein of unknown function; Region: DUF3971; pfam13116
357544001611	AsmA-like C-terminal region; Region: AsmA_1; pfam13109
357544001612	Aminodeoxychorismate lyase [Coenzyme transport and metabolism]; Region: COG1559
357544001613	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
357544001614	dimerization interface [polypeptide binding]; other site
357544001615	2-oxoglutarate-acceptor oxidoreductase subunit OorD; Reviewed; Region: oorD; PRK09626
357544001616	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
357544001617	2-oxoglutarate-acceptor oxidoreductase subunit OorA; Reviewed; Region: oorA; PRK09627
357544001618	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
357544001619	dimer interface [polypeptide binding]; other site
357544001620	PYR/PP interface [polypeptide binding]; other site
357544001621	TPP binding site [chemical binding]; other site
357544001622	substrate binding site [chemical binding]; other site
357544001623	2-oxoglutarate-acceptor oxidoreductase subunit OorB; Reviewed; Region: oorB; PRK09628
357544001624	Thiamine pyrophosphate (TPP family), 2-oxoglutarate ferredoxin oxidoreductase (OGFOR) subfamily, TPP-binding module; OGFOR catalyzes the oxidative decarboxylation of 2-oxo-acids, with ferredoxin acting as an electron acceptor. In the TCA cycle, OGFOR...; Region: TPP_OGFOR; cd03375
357544001625	TPP-binding site [chemical binding]; other site
357544001626	2-oxoglutarate-acceptor oxidoreductase subunit OorC; Reviewed; Region: oorC; PRK08441
357544001627	2-oxoglutarate ferredoxin oxidoreductase subunit gamma; Validated; Region: PRK08537
357544001628	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG5610
357544001629	haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E; Region: HAD-SF-IA-v1; TIGR01549
357544001630	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG5610
357544001631	Disulfide bond formation protein DsbB [Posttranslational modification, protein turnover, chaperones]; Region: DsbB; COG1495
357544001632	tumor necrosis factor alpha-inducing protein; Reviewed; Region: PRK12303
357544001633	Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]; Region: MrcB; COG0744
357544001634	Transglycosylase; Region: Transgly; pfam00912
357544001635	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
357544001636	7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism]; Region: BioF; COG0156
357544001637	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
357544001638	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
357544001639	catalytic residue [active]
357544001640	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
357544001641	dimer interface [polypeptide binding]; other site
357544001642	putative CheW interface [polypeptide binding]; other site
357544001643	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
357544001644	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
357544001645	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
357544001646	Walker A/P-loop; other site
357544001647	ATP binding site [chemical binding]; other site
357544001648	Q-loop/lid; other site
357544001649	ABC transporter signature motif; other site
357544001650	Walker B; other site
357544001651	D-loop; other site
357544001652	H-loop/switch region; other site
357544001653	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
357544001654	flagellin A; Reviewed; Region: PRK12584
357544001655	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
357544001656	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
357544001657	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
357544001658	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
357544001659	3-methyladenine DNA glycosylase; Provisional; Region: PRK13913
357544001660	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
357544001661	minor groove reading motif; other site
357544001662	helix-hairpin-helix signature motif; other site
357544001663	active site
357544001664	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
357544001665	substrate binding site [chemical binding]; other site
357544001666	active site
357544001667	Outer membrane efflux protein; Region: OEP; pfam02321
357544001668	Outer membrane efflux protein; Region: OEP; pfam02321
357544001669	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
357544001670	HlyD family secretion protein; Region: HlyD_3; pfam13437
357544001671	AcrB/AcrD/AcrF family; Region: ACR_tran; pfam00873
357544001672	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544001673	PPE-repeat proteins [Cell motility and secretion]; Region: COG5651
357544001674	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
357544001675	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
357544001676	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
357544001677	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
357544001678	PPE-repeat proteins [Cell motility and secretion]; Region: COG5651
357544001679	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
357544001680	Autotransporter beta-domain; Region: Autotransporter; pfam03797
357544001681	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
357544001682	ABC transporter signature motif; other site
357544001683	Walker B; other site
357544001684	D-loop; other site
357544001685	H-loop/switch region; other site
357544001686	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
357544001687	Walker A/P-loop; other site
357544001688	ATP binding site [chemical binding]; other site
357544001689	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
357544001690	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
357544001691	nucleotide binding pocket [chemical binding]; other site
357544001692	K-X-D-G motif; other site
357544001693	catalytic site [active]
357544001694	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
357544001695	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
357544001696	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
357544001697	Dimer interface [polypeptide binding]; other site
357544001698	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cd00588
357544001699	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
357544001700	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
357544001701	active site
357544001702	phosphorylation site [posttranslational modification]
357544001703	intermolecular recognition site; other site
357544001704	dimerization interface [polypeptide binding]; other site
357544001705	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
357544001706	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
357544001707	dimer interface [polypeptide binding]; other site
357544001708	anticodon binding site; other site
357544001709	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
357544001710	homodimer interface [polypeptide binding]; other site
357544001711	motif 1; other site
357544001712	active site
357544001713	motif 2; other site
357544001714	GAD domain; Region: GAD; pfam02938
357544001715	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
357544001716	active site
357544001717	motif 3; other site
357544001718	adenylate kinase; Reviewed; Region: adk; PRK00279
357544001719	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
357544001720	AMP-binding site [chemical binding]; other site
357544001721	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
357544001722	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
357544001723	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cl01298
357544001724	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
357544001725	Glycosyltransferase involved in LPS biosynthesis [Cell envelope biogenesis, outer membrane]; Region: COG3306
357544001726	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
357544001727	dimer interface [polypeptide binding]; other site
357544001728	substrate binding site [chemical binding]; other site
357544001729	metal binding sites [ion binding]; metal-binding site
357544001730	MutS2 family protein; Region: mutS2; TIGR01069
357544001731	ATPase domain of DNA mismatch repair MUTS family; Region: MUTSac; smart00534
357544001732	Walker A/P-loop; other site
357544001733	ATP binding site [chemical binding]; other site
357544001734	Q-loop/lid; other site
357544001735	ABC transporter signature motif; other site
357544001736	Walker B; other site
357544001737	D-loop; other site
357544001738	H-loop/switch region; other site
357544001739	Smr domain; Region: Smr; pfam01713
357544001740	UDP-N-acetylmuramate--alanine ligase; Region: murC; TIGR01082
357544001741	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
357544001742	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
357544001743	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
357544001744	hypothetical protein; Provisional; Region: PRK05839
357544001745	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
357544001746	pyridoxal 5'-phosphate binding site [chemical binding]; other site
357544001747	homodimer interface [polypeptide binding]; other site
357544001748	catalytic residue [active]
357544001749	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
357544001750	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
357544001751	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
357544001752	Tetrahydrodipicolinate N-succinyltransferase [Amino acid transport and metabolism]; Region: DapD; COG2171
357544001753	Putative 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (THP succinyltransferase), C-terminal left-handed parallel alpha-helix (LbH) domain: This group is composed of mostly uncharacterized proteins containing an N-terminal...; Region: LbH_THP_succinylT_putative; cd04649
357544001754	putative trimer interface [polypeptide binding]; other site
357544001755	putative CoA binding site [chemical binding]; other site
357544001756	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
357544001757	Sel1-like repeats; Region: SEL1; smart00671
357544001758	Sel1-like repeats; Region: SEL1; smart00671
357544001759	Sel1 repeat; Region: Sel1; cl02723
357544001760	Sel1-like repeats; Region: SEL1; smart00671
357544001761	Uncharacterized conserved protein [Function unknown]; Region: COG1479
357544001762	Protein of unknown function DUF262; Region: DUF262; pfam03235
357544001763	Uncharacterized conserved protein [Function unknown]; Region: COG1479
357544001764	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
357544001765	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
357544001766	hydrogenase (NiFe) small subunit (hydA); Region: hydA; TIGR00391
357544001767	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
357544001768	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
357544001769	Nickel-dependent hydrogenase; Region: NiFeSe_Hases; pfam00374
357544001770	Ni,Fe-hydrogenase I cytochrome b subunit [Energy production and conversion]; Region: HyaC; COG1969
357544001771	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
357544001772	nickel binding site [ion binding]; other site
357544001773	putative substrate-binding site; other site
357544001774	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544001775	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
357544001776	Ligand Binding Site [chemical binding]; other site
357544001777	tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; Region: PcnB; COG0617
357544001778	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
357544001779	active site
357544001780	NTP binding site [chemical binding]; other site
357544001781	metal binding triad [ion binding]; metal-binding site
357544001782	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
357544001783	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
357544001784	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
357544001785	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
357544001786	dimer interface [polypeptide binding]; other site
357544001787	FMN binding site [chemical binding]; other site
357544001788	glutamylglutaminyl-tRNA synthetase; Provisional; Region: PRK12410
357544001789	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
357544001790	active site
357544001791	HIGH motif; other site
357544001792	nucleotide binding site [chemical binding]; other site
357544001793	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
357544001794	active site
357544001795	KMSKS motif; other site
357544001796	YGGT family; Region: YGGT; pfam02325
357544001797	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
357544001798	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
357544001799	N-acetyl-D-glucosamine binding site [chemical binding]; other site
357544001800	catalytic residue [active]
357544001801	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
357544001802	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
357544001803	active site
357544001804	tetramer interface; other site
357544001805	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
357544001806	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
357544001807	hinge; other site
357544001808	active site
357544001809	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
357544001810	Aspartase; Region: Aspartase; cd01357
357544001811	active sites [active]
357544001812	tetramer interface [polypeptide binding]; other site
357544001813	Uracil-DNA glycosylases (UDG) and related enzymes; Region: UDG_like; cl00483
357544001814	ligand binding site [chemical binding]; other site
357544001815	active site
357544001816	Glycosyltransferase family 10 (fucosyltransferase); Region: Glyco_transf_10; pfam00852
357544001817	phosphoserine phosphatase SerB; Region: serB; TIGR00338
357544001818	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
357544001819	motif II; other site
357544001820	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
357544001821	Ferritin-like domain; Region: Ferritin; pfam00210
357544001822	ferroxidase diiron center [ion binding]; other site
357544001823	hypothetical protein; Provisional; Region: PRK08444
357544001824	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
357544001825	FeS/SAM binding site; other site
357544001826	Outer membrane protein/protective antigen OMA87 [Cell envelope biogenesis, outer membrane]; Region: COG4775
357544001827	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
357544001828	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
357544001829	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
357544001830	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
357544001831	Surface antigen; Region: Bac_surface_Ag; pfam01103
357544001832	hypothetical protein; Provisional; Region: PRK08445
357544001833	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
357544001834	FeS/SAM binding site; other site
357544001835	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
357544001836	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
357544001837	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
357544001838	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
357544001839	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
357544001840	GatB domain; Region: GatB_Yqey; smart00845
357544001841	SurA N-terminal domain; Region: SurA_N; pfam09312
357544001842	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
357544001843	Predicted nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module [General function prediction only]; Region: COG1439
357544001844	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
357544001845	RNA/DNA hybrid binding site [nucleotide binding]; other site
357544001846	active site
357544001847	ribonuclease III; Reviewed; Region: rnc; PRK00102
357544001848	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
357544001849	dimerization interface [polypeptide binding]; other site
357544001850	active site
357544001851	metal binding site [ion binding]; metal-binding site
357544001852	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
357544001853	dsRNA binding site [nucleotide binding]; other site
357544001854	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
357544001855	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
357544001856	Tetramer interface [polypeptide binding]; other site
357544001857	active site
357544001858	FMN-binding site [chemical binding]; other site
357544001859	Protein of unknown function (DUF2603); Region: DUF2603; pfam10788
357544001860	oxygen-independent coproporphyrinogen III oxidase; Region: hemN; TIGR00538
357544001861	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
357544001862	FeS/SAM binding site; other site
357544001863	HemN C-terminal domain; Region: HemN_C; pfam06969
357544001864	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
357544001865	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
357544001866	Cysteine-rich domain; Region: CCG; pfam02754
357544001867	Cysteine-rich domain; Region: CCG; pfam02754
357544001868	Restriction endonuclease; Region: Mrr_cat; pfam04471
357544001869	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
357544001870	Predicted helicase [General function prediction only]; Region: COG4889
357544001871	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
357544001872	putative Mg++ binding site [ion binding]; other site
357544001873	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
357544001874	nucleotide binding region [chemical binding]; other site
357544001875	ATP-binding site [chemical binding]; other site
357544001876	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544001877	aspartate aminotransferase; Provisional; Region: PRK05764
357544001878	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
357544001879	pyridoxal 5'-phosphate binding site [chemical binding]; other site
357544001880	homodimer interface [polypeptide binding]; other site
357544001881	catalytic residue [active]
357544001882	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13645
357544001883	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
357544001884	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
357544001885	active site
357544001886	DNA binding site [nucleotide binding]
357544001887	Int/Topo IB signature motif; other site
357544001888	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
357544001889	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
357544001890	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
357544001891	DNA binding site [nucleotide binding]
357544001892	active site
357544001893	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
357544001894	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
357544001895	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
357544001896	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
357544001897	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08447
357544001898	ATP cone domain; Region: ATP-cone; pfam03477
357544001899	Class I ribonucleotide reductase; Region: RNR_I; cd01679
357544001900	active site
357544001901	dimer interface [polypeptide binding]; other site
357544001902	catalytic residues [active]
357544001903	effector binding site; other site
357544001904	R2 peptide binding site; other site
357544001905	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14359
357544001906	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
357544001907	Substrate binding site; other site
357544001908	Mg++ binding site; other site
357544001909	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
357544001910	active site
357544001911	substrate binding site [chemical binding]; other site
357544001912	CoA binding site [chemical binding]; other site
357544001913	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
357544001914	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
357544001915	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
357544001916	N-terminal plug; other site
357544001917	ligand-binding site [chemical binding]; other site
357544001918	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
357544001919	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
357544001920	G1 box; other site
357544001921	GTP/Mg2+ binding site [chemical binding]; other site
357544001922	Switch I region; other site
357544001923	G2 box; other site
357544001924	G3 box; other site
357544001925	Switch II region; other site
357544001926	G4 box; other site
357544001927	G5 box; other site
357544001928	Nucleoside recognition; Region: Gate; pfam07670
357544001929	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
357544001930	Nucleoside recognition; Region: Gate; pfam07670
357544001931	Uncharacterized bacterial subgroup of the DEDDy 3'-5' exonuclease domain of family-B DNA polymerases; Region: DNA_polB_like1_exo; cd05782
357544001932	active site
357544001933	catalytic site [active]
357544001934	substrate binding site [chemical binding]; other site
357544001935	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB; Region: DNA_pol_B_exo2; pfam10108
357544001936	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
357544001937	DNA methylase; Region: N6_N4_Mtase; pfam01555
357544001938	CfrBI restriction endonuclease; Region: RE_CfrBI; pfam09516
357544001939	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB [DNA replication, recombination, and repair]; Region: COG3298
357544001940	putative acyltransferase; Provisional; Region: PRK05790
357544001941	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
357544001942	dimer interface [polypeptide binding]; other site
357544001943	active site
357544001944	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788
357544001945	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
357544001946	Short chain fatty acid transporter; Region: SCFA_trans; pfam02667
357544001947	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3528
357544001948	N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuA; COG0145
357544001949	Hydantoinase/oxoprolinase N-terminal region; Region: Hydant_A_N; pfam05378
357544001950	Hydantoinase/oxoprolinase; Region: Hydantoinase_A; pfam01968
357544001951	N-methylhydantoinase B/acetone carboxylase, alpha subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuB; COG0146
357544001952	Hydantoinase B/oxoprolinase; Region: Hydantoinase_B; pfam02538
357544001953	Acetone carboxylase, gamma subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcxC; COG4647
357544001954	Acetone carboxylase gamma subunit; Region: Acetone_carb_G; pfam08882
357544001955	Uncharacterized conserved protein [Function unknown]; Region: COG1479
357544001956	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
357544001957	DNA gyrase subunit A; Validated; Region: PRK05560
357544001958	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
357544001959	CAP-like domain; other site
357544001960	active site
357544001961	primary dimer interface [polypeptide binding]; other site
357544001962	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
357544001963	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
357544001964	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
357544001965	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
357544001966	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
357544001967	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
357544001968	Response regulator receiver domain; Region: Response_reg; pfam00072
357544001969	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
357544001970	active site
357544001971	phosphorylation site [posttranslational modification]
357544001972	intermolecular recognition site; other site
357544001973	dimerization interface [polypeptide binding]; other site
357544001974	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
357544001975	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
357544001976	Walker A motif; other site
357544001977	ATP binding site [chemical binding]; other site
357544001978	Walker B motif; other site
357544001979	arginine finger; other site
357544001980	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
357544001981	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
357544001982	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
357544001983	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
357544001984	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544001985	Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG0275
357544001986	16S rRNA (cytosine(1402)-N(4))-methyltransferase; Region: TIGR00006
357544001987	Uncharacterized conserved protein [Function unknown]; Region: COG1912
357544001988	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544001989	Competence protein ComGF [Intracellular trafficking and secretion]; Region: ComGF; COG4940
357544001990	Predicted hydrolases of HD superfamily [General function prediction only]; Region: COG1896
357544001991	Fic family protein [Function unknown]; Region: COG3177
357544001992	Fic family protein [Function unknown]; Region: COG3177
357544001993	Fic/DOC family; Region: Fic; pfam02661
357544001994	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
357544001995	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
357544001996	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
357544001997	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
357544001998	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
357544001999	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
357544002000	Walker A/P-loop; other site
357544002001	ATP binding site [chemical binding]; other site
357544002002	Q-loop/lid; other site
357544002003	ABC transporter signature motif; other site
357544002004	Walker B; other site
357544002005	D-loop; other site
357544002006	H-loop/switch region; other site
357544002007	Uncharacterized P-loop hydrolase UPF0079; Region: UPF0079; cl00520
357544002008	DNA polymerase III, gamma/tau subunits [DNA replication, recombination, and repair]; Region: DnaX; COG2812
357544002009	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
357544002010	Walker A motif; other site
357544002011	ATP binding site [chemical binding]; other site
357544002012	Walker B motif; other site
357544002013	arginine finger; other site
357544002014	Lysine efflux permease [General function prediction only]; Region: COG1279
357544002015	Protein of unknown function (DUF1104); Region: DUF1104; pfam06518
357544002016	Protein of unknown function (DUF1104); Region: DUF1104; pfam06518
357544002017	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544002018	anaerobic c4-dicarboxylate membrane transporter family protein; Region: Dcu; TIGR00770
357544002019	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
357544002020	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
357544002021	active site
357544002022	homodimer interface [polypeptide binding]; other site
357544002023	homotetramer interface [polypeptide binding]; other site
357544002024	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544002025	tRNA-dihydrouridine synthase [Translation, ribosomal structure and biogenesis]; Region: COG0042
357544002026	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
357544002027	FMN binding site [chemical binding]; other site
357544002028	active site
357544002029	catalytic residues [active]
357544002030	substrate binding site [chemical binding]; other site
357544002031	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
357544002032	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
357544002033	Ligand Binding Site [chemical binding]; other site
357544002034	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
357544002035	G1 box; other site
357544002036	GTP/Mg2+ binding site [chemical binding]; other site
357544002037	G2 box; other site
357544002038	Switch I region; other site
357544002039	G3 box; other site
357544002040	Switch II region; other site
357544002041	G4 box; other site
357544002042	cyclic beta-1,2-glucan ABC transporter; Provisional; Region: PRK13657
357544002043	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
357544002044	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
357544002045	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
357544002046	FeS/SAM binding site; other site
357544002047	Predicted phosphoribosyltransferases [General function prediction only]; Region: COG2236
357544002048	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
357544002049	active site
357544002050	Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075
357544002051	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
357544002052	catalytic residue [active]
357544002053	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
357544002054	tetramer interfaces [polypeptide binding]; other site
357544002055	binuclear metal-binding site [ion binding]; other site
357544002056	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
357544002057	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
357544002058	ATP-grasp domain; Region: ATP-grasp_4; cl17255
357544002059	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
357544002060	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
357544002061	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
357544002062	FHIT (fragile histidine family): FHIT proteins, related to the HIT family carry a motif HxHxH/Qxx (x, is a hydrophobic amino acid), On the basis of sequence, substrate specificity, structure, evolution and mechanism, HIT proteins are classified into...; Region: FHIT; cd01275
357544002063	nucleotide binding site/active site [active]
357544002064	HIT family signature motif; other site
357544002065	catalytic residue [active]
357544002066	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
357544002067	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
357544002068	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
357544002069	active site
357544002070	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
357544002071	Uncharacterized protein/domain associated with GTPases [Function unknown]; Region: COG3597
357544002072	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
357544002073	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
357544002074	G1 box; other site
357544002075	G1 box; other site
357544002076	GTP/Mg2+ binding site [chemical binding]; other site
357544002077	GTP/Mg2+ binding site [chemical binding]; other site
357544002078	G2 box; other site
357544002079	Switch I region; other site
357544002080	G3 box; other site
357544002081	Switch II region; other site
357544002082	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
357544002083	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
357544002084	RNA binding surface [nucleotide binding]; other site
357544002085	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
357544002086	active site
357544002087	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
357544002088	Fibronectin type 3 domain-containing protein [General function prediction only]; Region: COG3401
357544002089	Interdomain contacts; other site
357544002090	Cytokine receptor motif; other site
357544002091	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
357544002092	Interdomain contacts; other site
357544002093	Cytokine receptor motif; other site
357544002094	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
357544002095	Interdomain contacts; other site
357544002096	Cytokine receptor motif; other site
357544002097	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
357544002098	S-adenosylmethionine binding site [chemical binding]; other site
357544002099	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
357544002100	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
357544002101	Walker A/P-loop; other site
357544002102	ATP binding site [chemical binding]; other site
357544002103	Q-loop/lid; other site
357544002104	ABC transporter signature motif; other site
357544002105	Walker B; other site
357544002106	D-loop; other site
357544002107	H-loop/switch region; other site
357544002108	Cell division protein [Cell division and chromosome partitioning]; Region: FtsX; COG2177
357544002109	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
357544002110	Peptidase family M23; Region: Peptidase_M23; pfam01551
357544002111	flagellar protein FlaG; Provisional; Region: PRK08452
357544002112	flagellar capping protein; Validated; Region: fliD; PRK08453
357544002113	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
357544002114	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
357544002115	flagellar biosynthetic protein FliS; Region: fliS; TIGR00208
357544002116	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism]; Region: COG1179
357544002117	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
357544002118	putative ATP binding site [chemical binding]; other site
357544002119	putative substrate interface [chemical binding]; other site
357544002120	N-carbamoylputrescine amidohydrolase (CPA) (class 11 nitrilases); Region: CPA; cd07573
357544002121	N-carbamoylputrescine amidase; Region: agmatine_aguB; TIGR03381
357544002122	putative active site; other site
357544002123	catalytic triad [active]
357544002124	putative dimer interface [polypeptide binding]; other site
357544002125	Predicted permease [General function prediction only]; Region: COG2056
357544002126	Na+-H+ antiporter family; Region: Na_H_antiport_2; pfam13726
357544002127	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
357544002128	putative efflux protein, MATE family; Region: matE; TIGR00797
357544002129	phosphodiesterase; Provisional; Region: PRK12704
357544002130	K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; Region: KH-I; cd00105
357544002131	nucleic acid binding region [nucleotide binding]; other site
357544002132	G-X-X-G motif; other site
357544002133	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
357544002134	Zn2+ binding site [ion binding]; other site
357544002135	Mg2+ binding site [ion binding]; other site
357544002136	5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism]; Region: COG0212
357544002137	signal recognition particle-docking protein FtsY; Region: ftsY; TIGR00064
357544002138	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
357544002139	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
357544002140	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
357544002141	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
357544002142	FeS/SAM binding site; other site
357544002143	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
357544002144	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
357544002145	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
357544002146	GTP binding site; other site
357544002147	flagellar biosynthetic protein FlhB; Region: flhB; TIGR00328
357544002148	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
357544002149	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
357544002150	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
357544002151	active site
357544002152	metal binding site [ion binding]; metal-binding site
357544002153	Nitronate monooxygenase; Region: NMO; pfam03060
357544002154	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
357544002155	FMN binding site [chemical binding]; other site
357544002156	substrate binding site [chemical binding]; other site
357544002157	putative catalytic residue [active]
357544002158	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
357544002159	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
357544002160	active site
357544002161	HIGH motif; other site
357544002162	dimer interface [polypeptide binding]; other site
357544002163	KMSKS motif; other site
357544002164	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
357544002165	RNA binding surface [nucleotide binding]; other site
357544002166	(p)ppGpp synthetase, RelA/SpoT family; Region: spoT_relA; TIGR00691
357544002167	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
357544002168	Zn2+ binding site [ion binding]; other site
357544002169	Mg2+ binding site [ion binding]; other site
357544002170	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
357544002171	synthetase active site [active]
357544002172	NTP binding site [chemical binding]; other site
357544002173	metal binding site [ion binding]; metal-binding site
357544002174	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
357544002175	DNA-directed RNA polymerase, subunit K/omega [Transcription]; Region: RpoZ; COG1758
357544002176	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
357544002177	putative nucleotide binding site [chemical binding]; other site
357544002178	uridine monophosphate binding site [chemical binding]; other site
357544002179	homohexameric interface [polypeptide binding]; other site
357544002180	Predicted periplasmic solute-binding protein [General function prediction only]; Region: COG1427
357544002181	aconitate hydratase 2; Region: acnB; TIGR00117
357544002182	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
357544002183	substrate binding site [chemical binding]; other site
357544002184	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
357544002185	substrate binding site [chemical binding]; other site
357544002186	ligand binding site [chemical binding]; other site
357544002187	FOG: Transposase [DNA replication, recombination, and repair]; Region: COG5659
357544002188	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
357544002189	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
357544002190	Outer membrane lipoprotein carrier protein LolA; Region: LolA; pfam03548
357544002191	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
357544002192	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
357544002193	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
357544002194	nucleotide binding region [chemical binding]; other site
357544002195	ATP-binding site [chemical binding]; other site
357544002196	SEC-C motif; Region: SEC-C; pfam02810
357544002197	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
357544002198	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
357544002199	FtsX-like permease family; Region: FtsX; pfam02687
357544002200	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
357544002201	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
357544002202	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
357544002203	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
357544002204	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cl00207
357544002205	metal-binding site [ion binding]
357544002206	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
357544002207	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
357544002208	Soluble P-type ATPase [General function prediction only]; Region: COG4087
357544002209	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
357544002210	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
357544002211	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
357544002212	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
357544002213	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
357544002214	active site
357544002215	catalytic residues [active]
357544002216	metal binding site [ion binding]; metal-binding site
357544002217	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
357544002218	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
357544002219	oligomer interface [polypeptide binding]; other site
357544002220	active site residues [active]
357544002221	trigger factor; Provisional; Region: tig; PRK01490
357544002222	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
357544002223	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
357544002224	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544002225	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
357544002226	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
357544002227	trimer interface [polypeptide binding]; other site
357544002228	dimer interface [polypeptide binding]; other site
357544002229	putative active site [active]
357544002230	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
357544002231	MPT binding site; other site
357544002232	trimer interface [polypeptide binding]; other site
357544002233	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
357544002234	MoaE homodimer interface [polypeptide binding]; other site
357544002235	MoaD interaction [polypeptide binding]; other site
357544002236	active site residues [active]
357544002237	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
357544002238	MoaE interaction surface [polypeptide binding]; other site
357544002239	MoeB interaction surface [polypeptide binding]; other site
357544002240	thiocarboxylated glycine; other site
357544002241	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
357544002242	dimerization interface [polypeptide binding]; other site
357544002243	active site
357544002244	Domain of unknown function (DUF3943); Region: DUF3943; pfam13084
357544002245	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09314
357544002246	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: ribB; TIGR00506
357544002247	GTP cyclohydrolase II [Coenzyme metabolism]; Region: RibA; COG0807
357544002248	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
357544002249	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
357544002250	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
357544002251	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
357544002252	N-terminal plug; other site
357544002253	ligand-binding site [chemical binding]; other site
357544002254	holo-[acyl-carrier-protein] synthase; Region: acpS; TIGR00516
357544002255	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK08455
357544002256	RNA methyltransferase, RsmD family; Region: TIGR00095
357544002257	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
357544002258	Uncharacterized conserved protein [Function unknown]; Region: COG1565
357544002259	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
357544002260	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 [Coenzyme metabolism]; Region: ThiF; COG0476
357544002261	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
357544002262	ATP binding site [chemical binding]; other site
357544002263	substrate interface [chemical binding]; other site
357544002264	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
357544002265	flagellar motor protein MotA; Validated; Region: PRK08456
357544002266	flagellar motor protein MotB; Reviewed; Region: motB; PRK08457
357544002267	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
357544002268	ligand binding site [chemical binding]; other site
357544002269	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
357544002270	dimer interface [polypeptide binding]; other site
357544002271	conserved gate region; other site
357544002272	ABC-ATPase subunit interface; other site
357544002273	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
357544002274	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
357544002275	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
357544002276	Walker A/P-loop; other site
357544002277	ATP binding site [chemical binding]; other site
357544002278	Q-loop/lid; other site
357544002279	ABC transporter signature motif; other site
357544002280	Walker B; other site
357544002281	D-loop; other site
357544002282	H-loop/switch region; other site
357544002283	excinuclease ABC, C subunit; Region: uvrC; TIGR00194
357544002284	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
357544002285	GIY-YIG motif/motif A; other site
357544002286	active site
357544002287	catalytic site [active]
357544002288	putative DNA binding site [nucleotide binding]; other site
357544002289	metal binding site [ion binding]; metal-binding site
357544002290	UvrB/uvrC motif; Region: UVR; pfam02151
357544002291	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
357544002292	homoserine dehydrogenase; Provisional; Region: PRK06349
357544002293	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
357544002294	ACT_HSDH_Hom CD includes the C-terminal ACT domain of the NAD(P)H-dependent, homoserine dehydrogenase (HSDH) and related domains; Region: ACT_HSDH-Hom; cd04881
357544002295	Predicted endonuclease distantly related to archaeal Holliday junction resolvase [DNA replication, recombination, and repair]; Region: COG0792
357544002296	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
357544002297	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
357544002298	catalytic residues [active]
357544002299	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
357544002300	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
357544002301	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
357544002302	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
357544002303	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cl01298
357544002304	RNA recognition motif in Helicobacter pylori HP0827 protein and similar proteins; Region: RRM_HP0827_like; cd12399
357544002305	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
357544002306	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
357544002307	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
357544002308	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
357544002309	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
357544002310	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
357544002311	active site
357544002312	aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit; Region: gatA; TIGR00132
357544002313	indole acetimide hydrolase; Validated; Region: PRK07488
357544002314	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
357544002315	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
357544002316	CoA-binding site [chemical binding]; other site
357544002317	spermidine synthase; Provisional; Region: speE; PRK00536
357544002318	spermidine synthase; Provisional; Region: PRK00811
357544002319	GTP-binding protein Der; Reviewed; Region: PRK00093
357544002320	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
357544002321	G1 box; other site
357544002322	GTP/Mg2+ binding site [chemical binding]; other site
357544002323	Switch I region; other site
357544002324	G2 box; other site
357544002325	Switch II region; other site
357544002326	G3 box; other site
357544002327	G4 box; other site
357544002328	G5 box; other site
357544002329	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
357544002330	G1 box; other site
357544002331	GTP/Mg2+ binding site [chemical binding]; other site
357544002332	Switch I region; other site
357544002333	G2 box; other site
357544002334	G3 box; other site
357544002335	Switch II region; other site
357544002336	G4 box; other site
357544002337	G5 box; other site
357544002338	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
357544002339	IHF dimer interface [polypeptide binding]; other site
357544002340	IHF - DNA interface [nucleotide binding]; other site
357544002341	LPP20 lipoprotein; Region: LPP20; cl15824
357544002342	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3018
357544002343	Long-chain fatty acid transport protein [Lipid metabolism]; Region: FadL; COG2067
357544002344	UDP-N-acetylglucosamine 4,6-dehydratase; Region: PseB; TIGR03589
357544002345	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
357544002346	NAD(P) binding site [chemical binding]; other site
357544002347	homodimer interface [polypeptide binding]; other site
357544002348	substrate binding site [chemical binding]; other site
357544002349	active site
357544002350	phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; Region: coaBC_dfp; TIGR00521
357544002351	Flavoprotein; Region: Flavoprotein; pfam02441
357544002352	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
357544002353	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
357544002354	thiamine phosphate binding site [chemical binding]; other site
357544002355	active site
357544002356	pyrophosphate binding site [ion binding]; other site
357544002357	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
357544002358	dimer interface [polypeptide binding]; other site
357544002359	substrate binding site [chemical binding]; other site
357544002360	ATP binding site [chemical binding]; other site
357544002361	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
357544002362	substrate binding site [chemical binding]; other site
357544002363	multimerization interface [polypeptide binding]; other site
357544002364	ATP binding site [chemical binding]; other site
357544002365	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
357544002366	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
357544002367	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
357544002368	ATP binding site [chemical binding]; other site
357544002369	putative Mg++ binding site [ion binding]; other site
357544002370	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
357544002371	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
357544002372	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
357544002373	type I restriction system adenine methylase (hsdM); Region: hsdM; TIGR00497
357544002374	HsdM N-terminal domain; Region: HsdM_N; pfam12161
357544002375	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
357544002376	S-adenosylmethionine binding site [chemical binding]; other site
357544002377	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
357544002378	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
357544002379	active site
357544002380	Protein of unknown function (DUF511); Region: DUF511; cl01114
357544002381	Protein of unknown function (DUF511); Region: DUF511; cl01114
357544002382	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
357544002383	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
357544002384	Walker A/P-loop; other site
357544002385	ATP binding site [chemical binding]; other site
357544002386	Q-loop/lid; other site
357544002387	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
357544002388	ABC transporter; Region: ABC_tran_2; pfam12848
357544002389	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
357544002390	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05458
357544002391	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
357544002392	active site
357544002393	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
357544002394	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
357544002395	dimer interface [polypeptide binding]; other site
357544002396	active site
357544002397	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaE; COG2870
357544002398	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
357544002399	putative ribose interaction site [chemical binding]; other site
357544002400	putative ADP binding site [chemical binding]; other site
357544002401	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
357544002402	active site
357544002403	nucleotide binding site [chemical binding]; other site
357544002404	HIGH motif; other site
357544002405	KMSKS motif; other site
357544002406	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
357544002407	ADP-L-glycero-D-manno-heptose-6-epimerase; Region: heptose_epim; TIGR02197
357544002408	NAD(P) binding site [chemical binding]; other site
357544002409	active site
357544002410	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
357544002411	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
357544002412	active site
357544002413	motif I; other site
357544002414	motif II; other site
357544002415	Uncharacterized conserved protein [Function unknown]; Region: COG2836
357544002416	pantothenate kinase; Reviewed; Region: PRK13333
357544002417	PQQ-like domain; Region: PQQ_2; pfam13360
357544002418	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
357544002419	trimer interface [polypeptide binding]; other site
357544002420	active site
357544002421	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
357544002422	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
357544002423	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
357544002424	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
357544002425	lipid-A-disaccharide synthase; Region: lpxB; TIGR00215
357544002426	hydrogenase nickel incorporation protein; Provisional; Region: hypA; PRK00564
357544002427	Hydrogenase expression/synthesis hypA family; Region: HypA; pfam01155
357544002428	flagellar hook protein FlgE; Validated; Region: flgE; PRK08425
357544002429	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
357544002430	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
357544002431	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
357544002432	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
357544002433	CDP-diacylglycerol pyrophosphatase, bacterial type; Region: cdh; TIGR00672
357544002434	alkylphosphonate utilization operon protein PhnA; Region: phnA; TIGR00686
357544002435	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
357544002436	PhnA protein; Region: PhnA; pfam03831
357544002437	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
357544002438	Clade 3 of the heme-binding enzyme catalase; Region: catalase_clade_3; cd08156
357544002439	tetramer interface [polypeptide binding]; other site
357544002440	heme binding pocket [chemical binding]; other site
357544002441	NADPH binding site [chemical binding]; other site
357544002442	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
357544002443	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
357544002444	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
357544002445	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
357544002446	active site
357544002447	putative DNA-binding cleft [nucleotide binding]; other site
357544002448	dimer interface [polypeptide binding]; other site
357544002449	Uncharacterized conserved protein [Function unknown]; Region: COG1432
357544002450	LabA_like proteins; Region: LabA_like; cd06167
357544002451	putative metal binding site [ion binding]; other site
357544002452	Protein of unknown function (DUF3519); Region: DUF3519; pfam12033
357544002453	Holliday junction DNA helicase, RuvA subunit; Region: ruvA; TIGR00084
357544002454	RuvA N terminal domain; Region: RuvA_N; pfam01330
357544002455	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
357544002456	MviN-like protein; Region: MVIN; pfam03023
357544002457	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
357544002458	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
357544002459	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
357544002460	active site
357544002461	HIGH motif; other site
357544002462	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
357544002463	KMSKS motif; other site
357544002464	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
357544002465	tRNA binding surface [nucleotide binding]; other site
357544002466	anticodon binding site; other site
357544002467	Vacuolating cyotoxin; Region: VacA; pfam02691
357544002468	Autotransporter beta-domain; Region: Autotransporter; pfam03797
357544002469	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
357544002470	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
357544002471	Ligand binding site; other site
357544002472	metal-binding site
357544002473	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
357544002474	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
357544002475	Walker A/P-loop; other site
357544002476	ATP binding site [chemical binding]; other site
357544002477	Q-loop/lid; other site
357544002478	ABC transporter signature motif; other site
357544002479	Walker B; other site
357544002480	D-loop; other site
357544002481	H-loop/switch region; other site
357544002482	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cl00462
357544002483	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
357544002484	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
357544002485	ABC-ATPase subunit  interface; other site
357544002486	dimer interface [polypeptide binding]; other site
357544002487	putative PBP binding regions; other site
357544002488	short chain dehydrogenase; Provisional; Region: PRK06914
357544002489	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
357544002490	NADP binding site [chemical binding]; other site
357544002491	active site
357544002492	steroid binding site; other site
357544002493	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
357544002494	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041
357544002495	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544002496	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
357544002497	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
357544002498	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypC; COG0298
357544002499	hydrogenase accessory protein HypB; Region: hypB; TIGR00073
357544002500	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
357544002501	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
357544002502	Acetokinase family; Region: Acetate_kinase; cl17229
357544002503	Acetokinase family; Region: Acetate_kinase; cl17229
357544002504	Phosphate acetyl/butaryl transferase; Region: PTA_PTB; cl17212
357544002505	BioD-like N-terminal domain of phosphotransacetylase [General function prediction only]; Region: Pta; COG0857
357544002506	Phosphate acetyl/butaryl transferase; Region: PTA_PTB; cl17212
357544002507	BioD-like N-terminal domain of phosphotransacetylase [General function prediction only]; Region: Pta; COG0857
357544002508	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
357544002509	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK05842
357544002510	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
357544002511	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
357544002512	flagellar hook protein FlgE; Validated; Region: flgE; PRK05841
357544002513	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
357544002514	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827
357544002515	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
357544002516	S-adenosylmethionine binding site [chemical binding]; other site
357544002517	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
357544002518	Part of AAA domain; Region: AAA_19; pfam13245
357544002519	Family description; Region: UvrD_C_2; pfam13538
357544002520	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544002521	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544002522	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
357544002523	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
357544002524	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
357544002525	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
357544002526	Telomere recombination; Region: Sua5_yciO_yrdC; cl00305
357544002527	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
357544002528	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
357544002529	ATP-grasp domain; Region: ATP-grasp_4; cl17255
357544002530	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
357544002531	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
357544002532	ATP-grasp domain; Region: ATP-grasp_4; cl17255
357544002533	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
357544002534	IMP binding site; other site
357544002535	dimer interface [polypeptide binding]; other site
357544002536	interdomain contacts; other site
357544002537	partial ornithine binding site; other site
357544002538	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
357544002539	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
357544002540	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
357544002541	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
357544002542	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
357544002543	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
357544002544	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
357544002545	PPE-repeat proteins [Cell motility and secretion]; Region: COG5651
357544002546	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
357544002547	Autotransporter beta-domain; Region: Autotransporter; pfam03797
357544002548	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544002549	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cd00491
357544002550	active site 1 [active]
357544002551	dimer interface [polypeptide binding]; other site
357544002552	hexamer interface [polypeptide binding]; other site
357544002553	active site 2 [active]
357544002554	recombination protein RecR; Region: recR; TIGR00615
357544002555	RecR protein; Region: RecR; pfam02132
357544002556	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
357544002557	putative active site [active]
357544002558	putative metal-binding site [ion binding]; other site
357544002559	tetramer interface [polypeptide binding]; other site
357544002560	tRNA pseudouridine synthase, TruD family; Region: tRNA_TruD_broad; TIGR00094
357544002561	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
357544002562	Permutation of conserved domain; other site
357544002563	active site
357544002564	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
357544002565	heat shock protein HtpX; Provisional; Region: PRK02870
357544002566	GTP cyclohydrolase I; Region: folE; TIGR00063
357544002567	GTP cyclohydrolase I; Provisional; Region: PLN03044
357544002568	active site
357544002569	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
357544002570	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
357544002571	substrate binding pocket [chemical binding]; other site
357544002572	chain length determination region; other site
357544002573	substrate-Mg2+ binding site; other site
357544002574	catalytic residues [active]
357544002575	aspartate-rich region 1; other site
357544002576	active site lid residues [active]
357544002577	aspartate-rich region 2; other site
357544002578	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
357544002579	6-pyruvoyl-tetrahydropterin synthase [Coenzyme metabolism]; Region: COG0720
357544002580	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
357544002581	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
357544002582	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
357544002583	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
357544002584	Coenzyme A binding pocket [chemical binding]; other site
357544002585	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544002586	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
357544002587	putative substrate translocation pore; other site
357544002588	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
357544002589	Uncharacterized conserved protein [Function unknown]; Region: COG1479
357544002590	Protein of unknown function DUF262; Region: DUF262; pfam03235
357544002591	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
357544002592	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
357544002593	dimer interface [polypeptide binding]; other site
357544002594	conserved gate region; other site
357544002595	putative PBP binding loops; other site
357544002596	ABC-ATPase subunit interface; other site
357544002597	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
357544002598	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
357544002599	substrate binding pocket [chemical binding]; other site
357544002600	membrane-bound complex binding site; other site
357544002601	hinge residues; other site
357544002602	alanine racemase; Region: alr; TIGR00492
357544002603	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
357544002604	active site
357544002605	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
357544002606	dimer interface [polypeptide binding]; other site
357544002607	substrate binding site [chemical binding]; other site
357544002608	catalytic residues [active]
357544002609	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
357544002610	amino acid carrier protein; Region: agcS; TIGR00835
357544002611	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
357544002612	Streptococcal 67 kDa myosin-cross-reactive antigen like family; Region: Strep_67kDa_ant; cl17487
357544002613	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
357544002614	homotrimer interaction site [polypeptide binding]; other site
357544002615	putative active site [active]
357544002616	TRL-like protein family; Region: TRL; pfam13146
357544002617	Na+/H+ antiporter [Energy production and conversion]; Region: NhaC; COG1757
357544002618	Uncharacterized conserved protein [Function unknown]; Region: COG1576
357544002619	acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Region: accD; TIGR00515
357544002620	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
357544002621	putative recombination protein RecO; Provisional; Region: PRK13908
357544002622	competence/damage-inducible protein CinA C-terminal domain; Region: cinA_cterm; TIGR00199
357544002623	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
357544002624	FMN binding site [chemical binding]; other site
357544002625	dimer interface [polypeptide binding]; other site
357544002626	prolipoprotein diacylglyceryl transferase; Region: lgt; TIGR00544
357544002627	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
357544002628	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
357544002629	active site
357544002630	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
357544002631	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
357544002632	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
357544002633	Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]; Region: COG1579
357544002634	Putative zinc ribbon domain; Region: DUF164; pfam02591
357544002635	dinuclear metal center protein, YbgI/SA1388 family; Region: YbgI_SA1388; TIGR00486
357544002636	Uncharacterized conserved protein [Function unknown]; Region: COG0327
357544002637	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
357544002638	dimer interface [polypeptide binding]; other site
357544002639	motif 1; other site
357544002640	active site
357544002641	motif 2; other site
357544002642	motif 3; other site
357544002643	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
357544002644	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
357544002645	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
357544002646	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
357544002647	Dynamin family; Region: Dynamin_N; pfam00350
357544002648	G1 box; other site
357544002649	GTP/Mg2+ binding site [chemical binding]; other site
357544002650	G2 box; other site
357544002651	Switch I region; other site
357544002652	G3 box; other site
357544002653	Switch II region; other site
357544002654	G4 box; other site
357544002655	G5 box; other site
357544002656	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
357544002657	G1 box; other site
357544002658	GTP/Mg2+ binding site [chemical binding]; other site
357544002659	G2 box; other site
357544002660	Switch I region; other site
357544002661	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
357544002662	G3 box; other site
357544002663	Switch II region; other site
357544002664	G4 box; other site
357544002665	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
357544002666	G1 box; other site
357544002667	GTP/Mg2+ binding site [chemical binding]; other site
357544002668	Predicted GTPases (dynamin-related) [General function prediction only]; Region: COG0699
357544002669	G2 box; other site
357544002670	Switch I region; other site
357544002671	G3 box; other site
357544002672	Switch II region; other site
357544002673	G4 box; other site
357544002674	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
357544002675	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
357544002676	Outer membrane efflux protein; Region: OEP; pfam02321
357544002677	glycyl-tRNA synthetase, tetrameric type, beta subunit; Region: glyS; TIGR00211
357544002678	phosphoglyceromutase; Provisional; Region: PRK05434
357544002679	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
357544002680	aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit; Region: gatC; TIGR00135
357544002681	adenosylmethionine--8-amino-7-oxononanoate transaminase; Provisional; Region: PRK05964
357544002682	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
357544002683	inhibitor-cofactor binding pocket; inhibition site
357544002684	pyridoxal 5'-phosphate binding site [chemical binding]; other site
357544002685	catalytic residue [active]
357544002686	SurA N-terminal domain; Region: SurA_N_3; cl07813
357544002687	peptidylprolyl isomerase; Provisional; Region: prsA; PRK00059
357544002688	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
357544002689	cell division protein FtsA; Region: ftsA; TIGR01174
357544002690	Cell division protein FtsA; Region: FtsA; smart00842
357544002691	Cell division protein FtsA; Region: FtsA; pfam14450
357544002692	cell division protein FtsZ; Validated; Region: PRK09330
357544002693	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
357544002694	nucleotide binding site [chemical binding]; other site
357544002695	SulA interaction site; other site
357544002696	Mechanosensitive ion channel; Region: MS_channel; pfam00924
357544002697	Uncharacterized conserved protein [Function unknown]; Region: COG1479
357544002698	Protein of unknown function DUF262; Region: DUF262; pfam03235
357544002699	Protein of unknown function DUF262; Region: DUF262; pfam03235
357544002700	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
357544002701	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
357544002702	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
357544002703	active site
357544002704	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
357544002705	catalytic residues [active]
357544002706	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
357544002707	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
357544002708	This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1; Region: GT1_UGDG_like; cd03817
357544002709	putative ADP-binding pocket [chemical binding]; other site
357544002710	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cd03440
357544002711	active site 2 [active]
357544002712	active site 1 [active]
357544002713	Methyltransferase domain; Region: Methyltransf_23; pfam13489
357544002714	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
357544002715	S-adenosylmethionine binding site [chemical binding]; other site
357544002716	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
357544002717	methionyl-tRNA synthetase; Reviewed; Region: PRK12267
357544002718	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
357544002719	active site
357544002720	HIGH motif; other site
357544002721	KMSKS motif; other site
357544002722	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
357544002723	anticodon binding site; other site
357544002724	tRNA binding surface [nucleotide binding]; other site
357544002725	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
357544002726	dimer interface [polypeptide binding]; other site
357544002727	putative tRNA-binding site [nucleotide binding]; other site
357544002728	Mycolic acid cyclopropane synthetase; Region: CMAS; pfam02353
357544002729	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
357544002730	S-adenosylmethionine binding site [chemical binding]; other site
357544002731	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
357544002732	Mechanosensitive ion channel; Region: MS_channel; pfam00924
357544002733	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
357544002734	GMP synthase; Reviewed; Region: guaA; PRK00074
357544002735	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
357544002736	AMP/PPi binding site [chemical binding]; other site
357544002737	candidate oxyanion hole; other site
357544002738	catalytic triad [active]
357544002739	potential glutamine specificity residues [chemical binding]; other site
357544002740	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
357544002741	ATP Binding subdomain [chemical binding]; other site
357544002742	Ligand Binding sites [chemical binding]; other site
357544002743	Dimerization subdomain; other site
357544002744	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
357544002745	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
357544002746	molybdopterin cofactor binding site [chemical binding]; other site
357544002747	substrate binding site [chemical binding]; other site
357544002748	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
357544002749	molybdopterin cofactor binding site; other site
357544002750	Protein of unknown function (DUF3972); Region: DUF3972; pfam13118
357544002751	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
357544002752	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
357544002753	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
357544002754	catalytic residue [active]
357544002755	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
357544002756	nucleotide binding site/active site [active]
357544002757	HIT family signature motif; other site
357544002758	catalytic residue [active]
357544002759	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
357544002760	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
357544002761	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
357544002762	dimer interface [polypeptide binding]; other site
357544002763	motif 1; other site
357544002764	active site
357544002765	motif 2; other site
357544002766	motif 3; other site
357544002767	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
357544002768	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
357544002769	putative tRNA-binding site [nucleotide binding]; other site
357544002770	tRNA synthetase B5 domain; Region: B5; pfam03484
357544002771	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
357544002772	dimer interface [polypeptide binding]; other site
357544002773	motif 1; other site
357544002774	motif 3; other site
357544002775	motif 2; other site
357544002776	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
357544002777	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
357544002778	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
357544002779	hinge; other site
357544002780	active site
357544002781	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
357544002782	LytB protein; Region: LYTB; pfam02401
357544002783	ribosomal protein S1; Region: rpsA; TIGR00717
357544002784	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
357544002785	RNA binding site [nucleotide binding]; other site
357544002786	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
357544002787	RNA binding site [nucleotide binding]; other site
357544002788	S1 RNA binding domain; Region: S1; pfam00575
357544002789	RNA binding site [nucleotide binding]; other site
357544002790	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
357544002791	RNA binding site [nucleotide binding]; other site
357544002792	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cd00164
357544002793	RNA binding site [nucleotide binding]; other site
357544002794	D-3-phosphoglycerate dehydrogenase; Region: PGDH; TIGR01327
357544002795	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_4; cd12173
357544002796	ligand binding site [chemical binding]; other site
357544002797	NAD binding site [chemical binding]; other site
357544002798	dimerization interface [polypeptide binding]; other site
357544002799	catalytic site [active]
357544002800	C-terminal ACT (regulatory) domain of D-3-phosphoglycerate dehydrogenase (3PGDH); Region: ACT_3PGDH-xct; cd04902
357544002801	putative L-serine binding site [chemical binding]; other site
357544002802	menaquinone biosynthesis decarboxylase, SCO4490 family; Region: mena_SCO4490; TIGR03701
357544002803	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; cl00311
357544002804	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
357544002805	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
357544002806	catalytic residue [active]
357544002807	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
357544002808	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
357544002809	putative active site [active]
357544002810	putative metal binding site [ion binding]; other site
357544002811	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
357544002812	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
357544002813	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
357544002814	active site
357544002815	phosphorylation site [posttranslational modification]
357544002816	intermolecular recognition site; other site
357544002817	dimerization interface [polypeptide binding]; other site
357544002818	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
357544002819	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
357544002820	putative binding surface; other site
357544002821	active site
357544002822	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
357544002823	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
357544002824	ATP binding site [chemical binding]; other site
357544002825	Mg2+ binding site [ion binding]; other site
357544002826	G-X-G motif; other site
357544002827	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
357544002828	Response regulator receiver domain; Region: Response_reg; pfam00072
357544002829	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
357544002830	active site
357544002831	phosphorylation site [posttranslational modification]
357544002832	intermolecular recognition site; other site
357544002833	dimerization interface [polypeptide binding]; other site
357544002834	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
357544002835	putative CheA interaction surface; other site
357544002836	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
357544002837	dimer interface [polypeptide binding]; other site
357544002838	catalytic triad [active]
357544002839	peroxidatic and resolving cysteines [active]
357544002840	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
357544002841	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
357544002842	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
357544002843	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
357544002844	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
357544002845	S-adenosylmethionine binding site [chemical binding]; other site
357544002846	primosome assembly protein PriA; Validated; Region: PRK05580
357544002847	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
357544002848	ATP binding site [chemical binding]; other site
357544002849	putative Mg++ binding site [ion binding]; other site
357544002850	helicase superfamily c-terminal domain; Region: HELICc; smart00490
357544002851	Sporulation related domain; Region: SPOR; pfam05036
357544002852	Peptidase family M48; Region: Peptidase_M48; pfam01435
357544002853	HemK family putative methylases; Region: hemK_fam; TIGR00536
357544002854	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
357544002855	glutamate dehydrogenase; Provisional; Region: PRK09414
357544002856	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
357544002857	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
357544002858	NAD(P) binding site [chemical binding]; other site
357544002859	Glycosyltransferase family 10 (fucosyltransferase); Region: Glyco_transf_10; pfam00852
357544002860	ResB protein required for cytochrome c biosynthesis [Posttranslational modification, protein turnover, chaperones]; Region: ResB; cl09125
357544002861	cytochrome c-type biogenesis protein CcsB; Region: cytochr_II_ccsB; TIGR03144
357544002862	SoxW family; SoxW is a bacterial periplasmic TRX, containing a redox active CXXC motif, encoded by a genetic locus (sox operon) involved in thiosulfate oxidation. Sulfur bacteria oxidize sulfur compounds to provide reducing equivalents for carbon dioxide...; Region: SoxW; cd02951
357544002863	catalytic residues [active]
357544002864	ferrochelatase; Region: hemH; TIGR00109
357544002865	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
357544002866	C-terminal domain interface [polypeptide binding]; other site
357544002867	active site
357544002868	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
357544002869	active site
357544002870	N-terminal domain interface [polypeptide binding]; other site
357544002871	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
357544002872	RNA methyltransferase, RsmE family; Region: TIGR00046
357544002873	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544002874	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
357544002875	trimer interface [polypeptide binding]; other site
357544002876	active site
357544002877	acetyl-CoA carboxylase, biotin carboxyl carrier protein; Region: BCCP; TIGR00531
357544002878	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
357544002879	carboxyltransferase (CT) interaction site; other site
357544002880	biotinylation site [posttranslational modification]; other site
357544002881	biotin carboxylase; Validated; Region: PRK08462
357544002882	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
357544002883	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
357544002884	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
357544002885	Methyltransferase domain; Region: Methyltransf_26; pfam13659
357544002886	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
357544002887	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
357544002888	inhibitor-cofactor binding pocket; inhibition site
357544002889	pyridoxal 5'-phosphate binding site [chemical binding]; other site
357544002890	catalytic residue [active]
357544002891	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
357544002892	dimer interface [polypeptide binding]; other site
357544002893	putative radical transfer pathway; other site
357544002894	diiron center [ion binding]; other site
357544002895	tyrosyl radical; other site
357544002896	protein-L-isoaspartate(D-aspartate) O-methyltransferase; Region: pimt; TIGR00080
357544002897	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
357544002898	S-adenosylmethionine binding site [chemical binding]; other site
357544002899	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
357544002900	Predicted permeases [General function prediction only]; Region: COG0795
357544002901	tRNA pseudouridine(38-40) synthase; Region: hisT_truA; TIGR00071
357544002902	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
357544002903	dimerization interface 3.5A [polypeptide binding]; other site
357544002904	active site
357544002905	UDP-glucose-4-epimerase GalE; Region: galE; TIGR01179
357544002906	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
357544002907	NAD binding site [chemical binding]; other site
357544002908	homodimer interface [polypeptide binding]; other site
357544002909	active site
357544002910	substrate binding site [chemical binding]; other site
357544002911	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
357544002912	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
357544002913	putative NAD(P) binding site [chemical binding]; other site
357544002914	homodimer interface [polypeptide binding]; other site
357544002915	homotetramer interface [polypeptide binding]; other site
357544002916	active site
357544002917	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
357544002918	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
357544002919	binding surface
357544002920	TPR motif; other site
357544002921	Sel1-like repeats; Region: SEL1; smart00671
357544002922	Sel1-like repeats; Region: SEL1; smart00671
357544002923	Sel1-like repeats; Region: SEL1; smart00671
357544002924	Entner-Doudoroff aldolase; Region: eda; TIGR01182
357544002925	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
357544002926	active site
357544002927	intersubunit interface [polypeptide binding]; other site
357544002928	catalytic residue [active]
357544002929	phosphogluconate dehydratase; Validated; Region: PRK09054
357544002930	6-phosphogluconate dehydratase; Region: edd; TIGR01196
357544002931	Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; Region: Zwf; COG0364
357544002932	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
357544002933	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
357544002934	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
357544002935	6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard...; Region: 6PGL; cd01400
357544002936	putative active site [active]
357544002937	glucokinase, proteobacterial type; Region: glk; TIGR00749
357544002938	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
357544002939	nucleotide binding site [chemical binding]; other site
357544002940	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
357544002941	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
357544002942	putative NAD(P) binding site [chemical binding]; other site
357544002943	putative substrate binding site [chemical binding]; other site
357544002944	catalytic Zn binding site [ion binding]; other site
357544002945	structural Zn binding site [ion binding]; other site
357544002946	dimer interface [polypeptide binding]; other site
357544002947	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
357544002948	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
357544002949	active site
357544002950	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
357544002951	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
357544002952	active site
357544002953	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544002954	pyruvate flavodoxin oxidoreductase subunit gamma; Validated; Region: PRK05844
357544002955	pyruvate/ketoisovalerate ferredoxin oxidoreductase subunit gamma; Provisional; Region: PRK14029
357544002956	pyruvate flavodoxin oxidoreductase subunit delta; Reviewed; Region: porD; PRK09625
357544002957	4Fe-4S binding domain; Region: Fer4; pfam00037
357544002958	pyruvate flavodoxin oxidoreductase subunit alpha; Reviewed; Region: porA; PRK09622
357544002959	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
357544002960	dimer interface [polypeptide binding]; other site
357544002961	PYR/PP interface [polypeptide binding]; other site
357544002962	TPP binding site [chemical binding]; other site
357544002963	substrate binding site [chemical binding]; other site
357544002964	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
357544002965	pyruvate ferredoxin oxidoreductase subunit beta; Provisional; Region: PRK11865
357544002966	Thiamine pyrophosphate (TPP family), PFOR porB-like subfamily, TPP-binding module; composed of proteins similar to the beta subunit (porB) of the Helicobacter pylori four-subunit pyruvate ferredoxin oxidoreductase (PFOR), which are also found in archaea...; Region: TPP_PFOR_porB_like; cd03376
357544002967	TPP-binding site [chemical binding]; other site
357544002968	putative dimer interface [polypeptide binding]; other site
357544002969	adenylosuccinate lyase; Provisional; Region: PRK08470
357544002970	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
357544002971	tetramer interface [polypeptide binding]; other site
357544002972	active site
357544002973	Adenylosuccinate lyase C-terminus; Region: ADSL_C; smart00998
357544002974	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544002975	excinuclease ABC subunit B; Provisional; Region: PRK05298
357544002976	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
357544002977	ATP binding site [chemical binding]; other site
357544002978	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
357544002979	putative Mg++ binding site [ion binding]; other site
357544002980	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
357544002981	nucleotide binding region [chemical binding]; other site
357544002982	ATP-binding site [chemical binding]; other site
357544002983	Ultra-violet resistance protein B; Region: UvrB; pfam12344
357544002984	UvrB/uvrC motif; Region: UVR; pfam02151
357544002985	Protein of unknown function (DUF3519); Region: DUF3519; pfam12033
357544002986	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
357544002987	binding surface
357544002988	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
357544002989	TPR motif; other site
357544002990	Sel1-like repeats; Region: SEL1; smart00671
357544002991	Sel1-like repeats; Region: SEL1; smart00671
357544002992	Sel1-like repeats; Region: SEL1; smart00671
357544002993	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
357544002994	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
357544002995	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08471
357544002996	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
357544002997	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
357544002998	DNA-methyltransferase (dcm); Region: dcm; TIGR00675
357544002999	cofactor binding site; other site
357544003000	DNA binding site [nucleotide binding]
357544003001	substrate interaction site [chemical binding]; other site
357544003002	Anti-sigma-28 factor, FlgM; Region: FlgM; cl01052
357544003003	FKBP-type peptidyl-prolyl cis-trans isomerases 2 [Posttranslational modification, protein turnover, chaperones]; Region: SlpA; COG1047
357544003004	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
357544003005	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
357544003006	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
357544003007	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
357544003008	ligand binding site [chemical binding]; other site
357544003009	translocation protein TolB; Provisional; Region: tolB; PRK04043
357544003010	TolB amino-terminal domain; Region: TolB_N; pfam04052
357544003011	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
357544003012	TonB C terminal; Region: TonB_2; pfam13103
357544003013	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
357544003014	TolR protein; Region: tolR; TIGR02801
357544003015	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; pfam01618
357544003016	ATP synthase, F1 epsilon subunit (delta in mitochondria); Region: ATP_synt_epsi; TIGR01216
357544003017	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
357544003018	gamma subunit interface [polypeptide binding]; other site
357544003019	epsilon subunit interface [polypeptide binding]; other site
357544003020	LBP interface [polypeptide binding]; other site
357544003021	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
357544003022	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
357544003023	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
357544003024	alpha subunit interaction interface [polypeptide binding]; other site
357544003025	Walker A motif; other site
357544003026	ATP binding site [chemical binding]; other site
357544003027	Walker B motif; other site
357544003028	inhibitor binding site; inhibition site
357544003029	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
357544003030	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
357544003031	core domain interface [polypeptide binding]; other site
357544003032	delta subunit interface [polypeptide binding]; other site
357544003033	epsilon subunit interface [polypeptide binding]; other site
357544003034	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
357544003035	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
357544003036	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
357544003037	beta subunit interaction interface [polypeptide binding]; other site
357544003038	Walker A motif; other site
357544003039	ATP binding site [chemical binding]; other site
357544003040	Walker B motif; other site
357544003041	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
357544003042	F0F1 ATP synthase subunit delta; Provisional; Region: PRK13431
357544003043	F0F1 ATP synthase subunit B; Validated; Region: PRK08475
357544003044	F0F1 ATP synthase subunit B'; Validated; Region: PRK08476
357544003045	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
357544003046	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
357544003047	ParB-like nuclease domain; Region: ParB; smart00470
357544003048	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
357544003049	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
357544003050	P-loop; other site
357544003051	Magnesium ion binding site [ion binding]; other site
357544003052	biotin--protein ligase; Provisional; Region: PRK08477
357544003053	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
357544003054	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
357544003055	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
357544003056	putative active site [active]
357544003057	substrate binding site [chemical binding]; other site
357544003058	putative cosubstrate binding site; other site
357544003059	catalytic site [active]
357544003060	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
357544003061	substrate binding site [chemical binding]; other site
357544003062	AAA domain; Region: AAA_13; pfam13166
357544003063	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4487
357544003064	Uncharacterized protein conserved in bacteria (DUF2130); Region: DUF2130; pfam09903
357544003065	Uncharacterized conserved protein [Function unknown]; Region: COG1432
357544003066	LabA_like proteins; Region: LabA_like; cd06167
357544003067	putative metal binding site [ion binding]; other site
357544003068	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
357544003069	tRNA (Guanine-1)-methyltransferase; Region: tRNA_m1G_MT; cl00407
357544003070	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK14593
357544003071	RimM N-terminal domain; Region: RimM; pfam01782
357544003072	PRC-barrel domain; Region: PRC; pfam05239
357544003073	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
357544003074	KH domain; Region: KH_4; pfam13083
357544003075	G-X-X-G motif; other site
357544003076	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
357544003077	signal recognition particle protein; Provisional; Region: PRK10867
357544003078	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
357544003079	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
357544003080	P loop; other site
357544003081	GTP binding site [chemical binding]; other site
357544003082	Signal peptide binding domain; Region: SRP_SPB; pfam02978
357544003083	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
357544003084	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
357544003085	active site
357544003086	HIGH motif; other site
357544003087	nucleotide binding site [chemical binding]; other site
357544003088	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
357544003089	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
357544003090	active site
357544003091	KMSKS motif; other site
357544003092	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
357544003093	anticodon binding site; other site
357544003094	flagellar assembly protein FliW; Provisional; Region: PRK13283
357544003095	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Region: murG; TIGR01133
357544003096	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
357544003097	active site
357544003098	homodimer interface [polypeptide binding]; other site
357544003099	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544003100	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544003101	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
357544003102	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
357544003103	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
357544003104	Fic/DOC family; Region: Fic; cl00960
357544003105	metal-binding heat shock protein; Provisional; Region: PRK00016
357544003106	flavodoxin FldA; Validated; Region: PRK09267
357544003107	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
357544003108	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
357544003109	Uncharacterized protein, possibly involved in nitrogen fixation [Inorganic ion transport and metabolism]; Region: FixS; COG3197
357544003110	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
357544003111	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
357544003112	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
357544003113	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
357544003114	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
357544003115	active site
357544003116	dimer interface [polypeptide binding]; other site
357544003117	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
357544003118	dimer interface [polypeptide binding]; other site
357544003119	active site
357544003120	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
357544003121	carbon starvation protein A; Provisional; Region: PRK15015
357544003122	Carbon starvation protein CstA; Region: CstA; pfam02554
357544003123	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
357544003124	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
357544003125	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
357544003126	dimer interface [polypeptide binding]; other site
357544003127	conserved gate region; other site
357544003128	putative PBP binding loops; other site
357544003129	ABC-ATPase subunit interface; other site
357544003130	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
357544003131	dimer interface [polypeptide binding]; other site
357544003132	conserved gate region; other site
357544003133	putative PBP binding loops; other site
357544003134	ABC-ATPase subunit interface; other site
357544003135	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
357544003136	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
357544003137	Walker A/P-loop; other site
357544003138	ATP binding site [chemical binding]; other site
357544003139	Q-loop/lid; other site
357544003140	ABC transporter signature motif; other site
357544003141	Walker B; other site
357544003142	D-loop; other site
357544003143	H-loop/switch region; other site
357544003144	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
357544003145	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
357544003146	substrate binding pocket [chemical binding]; other site
357544003147	membrane-bound complex binding site; other site
357544003148	hinge residues; other site
357544003149	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
357544003150	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
357544003151	putative substrate translocation pore; other site
357544003152	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
357544003153	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544003154	purine-nucleoside phosphorylase, family 1 (deoD); Region: deoD; TIGR00107
357544003155	phosphopentomutase; Provisional; Region: PRK05362
357544003156	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
357544003157	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
357544003158	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
357544003159	Nucleoside recognition; Region: Gate; pfam07670
357544003160	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
357544003161	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
357544003162	Major Facilitator Superfamily; Region: MFS_1; pfam07690
357544003163	putative substrate translocation pore; other site
357544003164	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
357544003165	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
357544003166	Ligand Binding Site [chemical binding]; other site
357544003167	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
357544003168	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
357544003169	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
357544003170	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
357544003171	putative arabinose transporter; Provisional; Region: PRK03545
357544003172	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
357544003173	putative substrate translocation pore; other site
357544003174	Carbonic anhydrase [Inorganic ion transport and metabolism]; Region: Cah; COG3338
357544003175	Carbonic anhydrase alpha, prokaryotic-like subfamily. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon...; Region: alpha_CA_prokaryotic_like; cd03124
357544003176	active site
357544003177	zinc binding site [ion binding]; other site
357544003178	Helicobacter pylori protein of unknown function (DUF874); Region: DUF874; pfam05917
357544003179	Helicobacter pylori protein of unknown function (DUF874); Region: DUF874; pfam05917
357544003180	Helicobacter pylori protein of unknown function (DUF874); Region: DUF874; pfam05917
357544003181	aspartate-semialdehyde dehydrogenase (peptidoglycan organisms); Region: asd_B; TIGR01296
357544003182	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
357544003183	Histidyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: HisS; COG0124
357544003184	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
357544003185	dimer interface [polypeptide binding]; other site
357544003186	motif 1; other site
357544003187	active site
357544003188	motif 2; other site
357544003189	motif 3; other site
357544003190	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
357544003191	anticodon binding site; other site
357544003192	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
357544003193	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
357544003194	putative active site [active]
357544003195	elongation factor G; Reviewed; Region: PRK00007
357544003196	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
357544003197	G1 box; other site
357544003198	putative GEF interaction site [polypeptide binding]; other site
357544003199	GTP/Mg2+ binding site [chemical binding]; other site
357544003200	Switch I region; other site
357544003201	G2 box; other site
357544003202	G3 box; other site
357544003203	Switch II region; other site
357544003204	G4 box; other site
357544003205	G5 box; other site
357544003206	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
357544003207	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
357544003208	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
357544003209	30S ribosomal protein S7; Validated; Region: PRK05302
357544003210	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
357544003211	S17 interaction site [polypeptide binding]; other site
357544003212	S8 interaction site; other site
357544003213	16S rRNA interaction site [nucleotide binding]; other site
357544003214	streptomycin interaction site [chemical binding]; other site
357544003215	23S rRNA interaction site [nucleotide binding]; other site
357544003216	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
357544003217	bifunctional DNA-directed RNA polymerase subunit beta/beta'; Reviewed; Region: PRK09603
357544003218	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
357544003219	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
357544003220	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
357544003221	RPB11 interaction site [polypeptide binding]; other site
357544003222	RPB12 interaction site [polypeptide binding]; other site
357544003223	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
357544003224	RPB3 interaction site [polypeptide binding]; other site
357544003225	RPB1 interaction site [polypeptide binding]; other site
357544003226	RPB11 interaction site [polypeptide binding]; other site
357544003227	RPB10 interaction site [polypeptide binding]; other site
357544003228	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
357544003229	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
357544003230	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
357544003231	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
357544003232	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
357544003233	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
357544003234	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
357544003235	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
357544003236	DNA binding site [nucleotide binding]
357544003237	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
357544003238	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
357544003239	core dimer interface [polypeptide binding]; other site
357544003240	peripheral dimer interface [polypeptide binding]; other site
357544003241	L10 interface [polypeptide binding]; other site
357544003242	L11 interface [polypeptide binding]; other site
357544003243	putative EF-Tu interaction site [polypeptide binding]; other site
357544003244	putative EF-G interaction site [polypeptide binding]; other site
357544003245	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
357544003246	23S rRNA interface [nucleotide binding]; other site
357544003247	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
357544003248	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
357544003249	mRNA/rRNA interface [nucleotide binding]; other site
357544003250	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
357544003251	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
357544003252	23S rRNA interface [nucleotide binding]; other site
357544003253	L7/L12 interface [polypeptide binding]; other site
357544003254	putative thiostrepton binding site; other site
357544003255	L25 interface [polypeptide binding]; other site
357544003256	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
357544003257	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
357544003258	putative homodimer interface [polypeptide binding]; other site
357544003259	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
357544003260	heterodimer interface [polypeptide binding]; other site
357544003261	homodimer interface [polypeptide binding]; other site
357544003262	Preprotein translocase subunit SecE [Intracellular trafficking and secretion]; Region: SecE; COG0690
357544003263	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
357544003264	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
357544003265	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
357544003266	Antibiotic Binding Site [chemical binding]; other site
357544003267	Elongation factor Tu GTP binding domain; Region: GTP_EFTU; pfam00009
357544003268	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
357544003269	G1 box; other site
357544003270	GEF interaction site [polypeptide binding]; other site
357544003271	GTP/Mg2+ binding site [chemical binding]; other site
357544003272	Switch I region; other site
357544003273	G2 box; other site
357544003274	G3 box; other site
357544003275	Switch II region; other site
357544003276	G4 box; other site
357544003277	G5 box; other site
357544003278	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
357544003279	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
357544003280	Walker A/P-loop; other site
357544003281	ATP binding site [chemical binding]; other site
357544003282	Q-loop/lid; other site
357544003283	ABC transporter signature motif; other site
357544003284	Walker B; other site
357544003285	D-loop; other site
357544003286	H-loop/switch region; other site
357544003287	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
357544003288	HAD-hyrolase-like; Region: Hydrolase_like; pfam13242
357544003289	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG3392
357544003290	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; pfam02086
357544003291	ICEA Protein; Region: ICEA; pfam05315
357544003292	ICEA Protein; Region: ICEA; pfam05315
357544003293	serine O-acetyltransferase; Region: cysE; TIGR01172
357544003294	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
357544003295	trimer interface [polypeptide binding]; other site
357544003296	active site
357544003297	substrate binding site [chemical binding]; other site
357544003298	CoA binding site [chemical binding]; other site
357544003299	F0F1 ATP synthase subunit C; Validated; Region: PRK08482
357544003300	RNase PH-like 3'-5' exoribonucleases; Region: RNase_PH; cl03114
357544003301	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
357544003302	oligomer interface [polypeptide binding]; other site
357544003303	RNA binding site [nucleotide binding]; other site
357544003304	RNase PH-like 3'-5' exoribonucleases; Region: RNase_PH; cl03114
357544003305	oligomer interface [polypeptide binding]; other site
357544003306	RNA binding site [nucleotide binding]; other site
357544003307	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
357544003308	putative nucleic acid binding region [nucleotide binding]; other site
357544003309	G-X-X-G motif; other site
357544003310	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
357544003311	RNA binding site [nucleotide binding]; other site
357544003312	Predicted phosphoribosyltransferases [General function prediction only]; Region: COG1926
357544003313	Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452
357544003314	Organic solvent tolerance protein; Region: OstA_C; pfam04453
357544003315	Predicted membrane protein/domain [Function unknown]; Region: COG1714
357544003316	phosphoribosylamine--glycine ligase; Region: purD; TIGR00877
357544003317	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
357544003318	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
357544003319	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
357544003320	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
357544003321	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
357544003322	Walker A/P-loop; other site
357544003323	ATP binding site [chemical binding]; other site
357544003324	Q-loop/lid; other site
357544003325	ABC transporter signature motif; other site
357544003326	Walker B; other site
357544003327	D-loop; other site
357544003328	H-loop/switch region; other site
357544003329	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
357544003330	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
357544003331	catalytic residue [active]
357544003332	putative FPP diphosphate  binding site; other site
357544003333	putative FPP binding hydrophobic cleft; other site
357544003334	dimer interface [polypeptide binding]; other site
357544003335	putative IPP diphosphate binding site; other site
357544003336	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
357544003337	FAD binding domain; Region: FAD_binding_4; pfam01565
357544003338	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
357544003339	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
357544003340	active site residue [active]
357544003341	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
357544003342	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
357544003343	active site
357544003344	camphor resistance protein CrcB; Provisional; Region: PRK14204
357544003345	coproporphyrinogen III oxidase; Provisional; Region: PRK08446
357544003346	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
357544003347	FeS/SAM binding site; other site
357544003348	HemN C-terminal domain; Region: HemN_C; pfam06969
357544003349	Cytochrome c553 [Energy production and conversion]; Region: COG2863
357544003350	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
357544003351	putative active site [active]
357544003352	Ap4A binding site [chemical binding]; other site
357544003353	nudix motif; other site
357544003354	putative metal binding site [ion binding]; other site
357544003355	aspartate kinase; Reviewed; Region: PRK06635
357544003356	AAK_AKii-LysC-BS: Amino Acid Kinase Superfamily (AAK), AKii; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis 168, and the lysine plus threonine-sensitive...; Region: AAK_AKii-LysC-BS; cd04261
357544003357	putative nucleotide binding site [chemical binding]; other site
357544003358	putative catalytic residues [active]
357544003359	putative Mg ion binding site [ion binding]; other site
357544003360	putative aspartate binding site [chemical binding]; other site
357544003361	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related proteins; Region: ACT_AKii-LysC-BS-like_1; cd04913
357544003362	putative allosteric regulatory site; other site
357544003363	ACT domains of the lysine-sensitive, aspartokinase (AK) isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AKii-LysC-BS-like_2; cd04936
357544003364	putative allosteric regulatory residue; other site
357544003365	DNA replication regulator; Region: HobA; pfam12163
357544003366	DNA polymerase III subunit delta'; Validated; Region: PRK08485
357544003367	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
357544003368	dihydropteroate synthase; Region: DHPS; TIGR01496
357544003369	substrate binding pocket [chemical binding]; other site
357544003370	dimer interface [polypeptide binding]; other site
357544003371	inhibitor binding site; inhibition site
357544003372	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
357544003373	EamA-like transporter family; Region: EamA; pfam00892
357544003374	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
357544003375	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2952
357544003376	Carbamoylphosphate synthase small subunit [Amino acid transport and metabolism / Nucleotide transport and metabolism]; Region: CarA; COG0505
357544003377	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; pfam00988
357544003378	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
357544003379	catalytic site [active]
357544003380	subunit interface [polypeptide binding]; other site
357544003381	formamidase; Provisional; Region: amiF; PRK13287
357544003382	aliphatic amidases (class 2 nitrilases); Region: aliphatic_amidase; cd07565
357544003383	multimer interface [polypeptide binding]; other site
357544003384	active site
357544003385	catalytic triad [active]
357544003386	dimer interface [polypeptide binding]; other site
357544003387	similar to hypothetical protein
357544003388	Maf-like protein; Region: Maf; pfam02545
357544003389	Maf-like protein; Reviewed; Region: PRK04056
357544003390	putative active site [active]
357544003391	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
357544003392	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
357544003393	motif 1; other site
357544003394	active site
357544003395	motif 2; other site
357544003396	motif 3; other site
357544003397	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
357544003398	DHHA1 domain; Region: DHHA1; pfam02272
357544003399	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2841
357544003400	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544003401	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
357544003402	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
357544003403	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
357544003404	dimer interface [polypeptide binding]; other site
357544003405	ssDNA binding site [nucleotide binding]; other site
357544003406	tetramer (dimer of dimers) interface [polypeptide binding]; other site
357544003407	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
357544003408	DNA polymerase III subunit delta; Validated; Region: PRK08487
357544003409	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
357544003410	Exoribonuclease R [Transcription]; Region: VacB; COG0557
357544003411	RNB domain; Region: RNB; pfam00773
357544003412	shikimate 5-dehydrogenase; Region: aroE; TIGR00507
357544003413	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
357544003414	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
357544003415	shikimate binding site; other site
357544003416	NAD(P) binding site [chemical binding]; other site
357544003417	Bacterial SH3 domain; Region: SH3_3; pfam08239
357544003418	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
357544003419	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
357544003420	dimer interface [polypeptide binding]; other site
357544003421	conserved gate region; other site
357544003422	putative PBP binding loops; other site
357544003423	ABC-ATPase subunit interface; other site
357544003424	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
357544003425	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
357544003426	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
357544003427	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
357544003428	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
357544003429	active site
357544003430	HIGH motif; other site
357544003431	dimer interface [polypeptide binding]; other site
357544003432	KMSKS motif; other site
357544003433	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
357544003434	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
357544003435	S-adenosylmethionine binding site [chemical binding]; other site
357544003436	Preprotein translocase subunit SecG [Intracellular trafficking and secretion]; Region: SecG; COG1314
357544003437	ribosome recycling factor; Reviewed; Region: frr; PRK00083
357544003438	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
357544003439	hinge region; other site
357544003440	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
357544003441	active site
357544003442	RDD family; Region: RDD; pfam06271
357544003443	NAD-dependent protein deacetylases, SIR2 family [Transcription]; Region: SIR2; COG0846
357544003444	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
357544003445	NAD+ binding site [chemical binding]; other site
357544003446	substrate binding site [chemical binding]; other site
357544003447	Zn binding site [ion binding]; other site
357544003448	NADH dehydrogenase subunit A; Validated; Region: PRK08489
357544003449	NADH dehydrogenase subunit B; Validated; Region: PRK06411
357544003450	NADH dehydrogenase subunit C; Provisional; Region: PRK08491
357544003451	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
357544003452	NADH dehydrogenase subunit D; Validated; Region: PRK06075
357544003453	NADH dehydrogenase I, D subunit; Region: NuoD; TIGR01962
357544003454	NADH dehydrogenase subunit G; Validated; Region: PRK08493
357544003455	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
357544003456	catalytic loop [active]
357544003457	iron binding site [ion binding]; other site
357544003458	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
357544003459	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
357544003460	molybdopterin cofactor binding site; other site
357544003461	Domain of unknown function (DUF4350); Region: DUF4350; pfam14258
357544003462	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
357544003463	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
357544003464	NADH-quinone oxidoreductase, chain I; Region: NuoI; TIGR01971
357544003465	4Fe-4S binding domain; Region: Fer4; cl02805
357544003466	4Fe-4S binding domain; Region: Fer4; pfam00037
357544003467	NADH:ubiquinone oxidoreductase subunit 6 (chain J) [Energy production and conversion]; Region: NuoJ; COG0839
357544003468	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
357544003469	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
357544003470	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
357544003471	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
357544003472	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
357544003473	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
357544003474	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
357544003475	proton-translocating NADH-quinone oxidoreductase, chain N; Region: NDH_I_N; TIGR01770
357544003476	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
357544003477	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
357544003478	putative PEP-CTERM system TPR-repeat lipoprotein; Region: PEP_TPR_lipo; TIGR02917
357544003479	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
357544003480	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
357544003481	active site
357544003482	substrate binding site [chemical binding]; other site
357544003483	metal binding site [ion binding]; metal-binding site
357544003484	Thiamine pyrophosphokinase [Coenzyme metabolism]; Region: THI80; COG1564
357544003485	Thiamine pyrophosphokinase; Region: TPK; cd07995
357544003486	active site
357544003487	dimerization interface [polypeptide binding]; other site
357544003488	thiamine binding site [chemical binding]; other site
357544003489	Nicotinamide mononucleotide transporter [Coenzyme metabolism]; Region: PnuC; COG3201
357544003490	thiaminase II; Region: salvage_TenA; TIGR04306
357544003491	Uncharacterized conserved protein [Function unknown]; Region: COG2353
357544003492	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
357544003493	active site
357544003494	motif I; other site
357544003495	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
357544003496	motif II; other site
357544003497	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
357544003498	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
357544003499	putative active site [active]
357544003500	anthranilate synthase component I, proteobacterial subset; Region: trpE_proteo; TIGR00565
357544003501	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
357544003502	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
357544003503	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
357544003504	Glutamine amidotransferase class-I; Region: GATase; pfam00117
357544003505	glutamine binding [chemical binding]; other site
357544003506	catalytic triad [active]
357544003507	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
357544003508	anthranilate phosphoribosyltransferase; Region: trpD; TIGR01245
357544003509	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
357544003510	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
357544003511	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
357544003512	active site
357544003513	ribulose/triose binding site [chemical binding]; other site
357544003514	phosphate binding site [ion binding]; other site
357544003515	substrate (anthranilate) binding pocket [chemical binding]; other site
357544003516	product (indole) binding pocket [chemical binding]; other site
357544003517	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
357544003518	active site
357544003519	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
357544003520	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
357544003521	pyridoxal 5'-phosphate binding site [chemical binding]; other site
357544003522	catalytic residue [active]
357544003523	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
357544003524	substrate binding site [chemical binding]; other site
357544003525	active site
357544003526	catalytic residues [active]
357544003527	heterodimer interface [polypeptide binding]; other site
357544003528	Thiamine pyrophosphokinase; Region: TPK; cl08415
357544003529	thiamine binding site [chemical binding]; other site
357544003530	Ribosomal protein L17 [Translation, ribosomal structure and biogenesis]; Region: RplQ; COG0203
357544003531	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
357544003532	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
357544003533	alphaNTD homodimer interface [polypeptide binding]; other site
357544003534	alphaNTD - beta interaction site [polypeptide binding]; other site
357544003535	alphaNTD - beta' interaction site [polypeptide binding]; other site
357544003536	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
357544003537	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
357544003538	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
357544003539	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
357544003540	RNA binding surface [nucleotide binding]; other site
357544003541	30S ribosomal protein S11; Validated; Region: PRK05309
357544003542	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
357544003543	30S ribosomal protein S13; Region: bact_S13; TIGR03631
357544003544	Ribosomal protein L36; Region: Ribosomal_L36; cl00380
357544003545	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
357544003546	rRNA binding site [nucleotide binding]; other site
357544003547	predicted 30S ribosome binding site; other site
357544003548	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
357544003549	active site
357544003550	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
357544003551	SecY translocase; Region: SecY; pfam00344
357544003552	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
357544003553	ribosomal protein S5, bacterial/organelle type; Region: rpsE_bact; TIGR01021
357544003554	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
357544003555	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
357544003556	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
357544003557	23S rRNA interface [nucleotide binding]; other site
357544003558	5S rRNA interface [nucleotide binding]; other site
357544003559	L27 interface [polypeptide binding]; other site
357544003560	L5 interface [polypeptide binding]; other site
357544003561	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
357544003562	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
357544003563	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
357544003564	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08061
357544003565	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
357544003566	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
357544003567	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
357544003568	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
357544003569	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
357544003570	RNA binding site [nucleotide binding]; other site
357544003571	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
357544003572	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
357544003573	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
357544003574	putative translocon interaction site; other site
357544003575	23S rRNA interface [nucleotide binding]; other site
357544003576	signal recognition particle (SRP54) interaction site; other site
357544003577	L23 interface [polypeptide binding]; other site
357544003578	trigger factor interaction site; other site
357544003579	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
357544003580	23S rRNA interface [nucleotide binding]; other site
357544003581	5S rRNA interface [nucleotide binding]; other site
357544003582	putative antibiotic binding site [chemical binding]; other site
357544003583	L25 interface [polypeptide binding]; other site
357544003584	L27 interface [polypeptide binding]; other site
357544003585	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
357544003586	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
357544003587	G-X-X-G motif; other site
357544003588	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
357544003589	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
357544003590	putative translocon binding site; other site
357544003591	protein-rRNA interface [nucleotide binding]; other site
357544003592	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
357544003593	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
357544003594	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
357544003595	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
357544003596	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
357544003597	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
357544003598	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
357544003599	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
357544003600	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
357544003601	AAA domain; Region: AAA_14; pfam13173
357544003602	Helix-turn-helix domain; Region: HTH_36; pfam13730
357544003603	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
357544003604	RNA/DNA hybrid binding site [nucleotide binding]; other site
357544003605	active site
357544003606	fumarate hydratase; Reviewed; Region: fumC; PRK00485
357544003607	Class II fumarases; Region: Fumarase_classII; cd01362
357544003608	active site
357544003609	tetramer interface [polypeptide binding]; other site
357544003610	YtkA-like; Region: YtkA; pfam13115
357544003611	Outer membrane efflux protein; Region: OEP; pfam02321
357544003612	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
357544003613	HlyD family secretion protein; Region: HlyD_3; pfam13437
357544003614	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
357544003615	Predicted branched-chain amino acid permeases (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlD; COG1687
357544003616	AzlC protein; Region: AzlC; cl00570
357544003617	chaperone protein DnaJ; Provisional; Region: PRK14288
357544003618	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
357544003619	HSP70 interaction site [polypeptide binding]; other site
357544003620	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
357544003621	substrate binding site [polypeptide binding]; other site
357544003622	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
357544003623	Zn binding sites [ion binding]; other site
357544003624	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
357544003625	dimer interface [polypeptide binding]; other site
357544003626	Uncharacterized conserved protein [Function unknown]; Region: COG1432
357544003627	LabA_like proteins; Region: LabA_like; cd06167
357544003628	putative metal binding site [ion binding]; other site
357544003629	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
357544003630	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
357544003631	Ligand Binding Site [chemical binding]; other site
357544003632	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
357544003633	HSP70 interaction site [polypeptide binding]; other site
357544003634	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
357544003635	Cytidylyltransferase; Region: CTP_transf_2; pfam01467
357544003636	active site
357544003637	(T/H)XGH motif; other site
357544003638	nickel responsive regulator; Provisional; Region: PRK00630
357544003639	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
357544003640	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
357544003641	tonB-system energizer ExbB, group 2; Region: exbB2; TIGR02805
357544003642	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
357544003643	Biopolymer transport protein ExbD/TolR; Region: ExbD; cl00537
357544003644	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
357544003645	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
357544003646	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544003647	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
357544003648	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
357544003649	Mg2+ transporter Helicobacter pylori CorA-like subgroup; Region: HpCorA-like; cd12836
357544003650	Cl binding site [ion binding]; other site
357544003651	oligomer interface [polypeptide binding]; other site
357544003652	phosphoglycerate kinase; Provisional; Region: pgk; PRK00073
357544003653	Phosphoglycerate kinase; Region: PGK; pfam00162
357544003654	substrate binding site [chemical binding]; other site
357544003655	hinge regions; other site
357544003656	ADP binding site [chemical binding]; other site
357544003657	catalytic site [active]
357544003658	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
357544003659	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
357544003660	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
357544003661	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
357544003662	ligand binding site [chemical binding]; other site
357544003663	active site
357544003664	UGI interface [polypeptide binding]; other site
357544003665	catalytic site [active]
357544003666	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
357544003667	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
357544003668	putative acyl-acceptor binding pocket; other site
357544003669	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
357544003670	C-terminal peptidase (prc); Region: prc; TIGR00225
357544003671	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
357544003672	protein binding site [polypeptide binding]; other site
357544003673	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
357544003674	Catalytic dyad [active]
357544003675	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
357544003676	DNA methylase; Region: N6_N4_Mtase; pfam01555
357544003677	Predicted helicase [General function prediction only]; Region: COG4889
357544003678	nicotinate-nucleotide pyrophosphorylase; Provisional; Region: PRK05848
357544003679	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
357544003680	dimerization interface [polypeptide binding]; other site
357544003681	active site
357544003682	Quinolinate synthetase A protein; Region: NadA; cl00420
357544003683	phosphatidylserine decarboxylase; Provisional; Region: PRK03934
357544003684	prenyltransferase; Reviewed; Region: ubiA; PRK12874
357544003685	UbiA prenyltransferase family; Region: UbiA; pfam01040
357544003686	Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658
357544003687	Competence protein; Region: Competence; pfam03772
357544003688	replicative DNA helicase; Provisional; Region: PRK08506
357544003689	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
357544003690	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
357544003691	Walker A motif; other site
357544003692	ATP binding site [chemical binding]; other site
357544003693	Walker B motif; other site
357544003694	DNA binding loops [nucleotide binding]
357544003695	yjeF N-terminal region; Region: yjeF_nterm; TIGR00197
357544003696	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
357544003697	putative substrate binding site [chemical binding]; other site
357544003698	putative ATP binding site [chemical binding]; other site
357544003699	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
357544003700	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
357544003701	dimer interface [polypeptide binding]; other site
357544003702	phosphorylation site [posttranslational modification]
357544003703	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
357544003704	ATP binding site [chemical binding]; other site
357544003705	Mg2+ binding site [ion binding]; other site
357544003706	G-X-G motif; other site
357544003707	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
357544003708	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
357544003709	active site
357544003710	phosphorylation site [posttranslational modification]
357544003711	intermolecular recognition site; other site
357544003712	dimerization interface [polypeptide binding]; other site
357544003713	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
357544003714	DNA binding site [nucleotide binding]
357544003715	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
357544003716	DNA methylase; Region: N6_N4_Mtase; pfam01555
357544003717	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
357544003718	DNA methylase; Region: N6_N4_Mtase; cl17433
357544003719	DNA methylase; Region: N6_N4_Mtase; pfam01555
357544003720	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
357544003721	DEAD-like helicases superfamily; Region: DEXDc; smart00487
357544003722	ATP binding site [chemical binding]; other site
357544003723	putative Mg++ binding site [ion binding]; other site
357544003724	Cell shape-determining protein [Cell envelope biogenesis, outer membrane]; Region: MreC; COG1792
357544003725	rod shape-determining protein MreC; Region: MreC; pfam04085
357544003726	rod shape-determining protein MreB; Provisional; Region: PRK13927
357544003727	MreB and similar proteins; Region: MreB_like; cd10225
357544003728	nucleotide binding site [chemical binding]; other site
357544003729	Mg binding site [ion binding]; other site
357544003730	putative protofilament interaction site [polypeptide binding]; other site
357544003731	RodZ interaction site [polypeptide binding]; other site
357544003732	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
357544003733	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
357544003734	Walker A motif; other site
357544003735	ATP binding site [chemical binding]; other site
357544003736	Walker B motif; other site
357544003737	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
357544003738	ClpX C4-type zinc finger; Region: zf-C4_ClpX; smart00994
357544003739	Acyl-[acyl carrier protein]; Region: LpxA; COG1043
357544003740	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
357544003741	active site
357544003742	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
357544003743	flagellar assembly protein FliW; Provisional; Region: PRK13282
357544003744	DNA uptake lipoprotein [General function prediction only]; Region: ComL; COG4105
357544003745	ATP-dependent protease La; Region: lon; TIGR00763
357544003746	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
357544003747	Walker A motif; other site
357544003748	ATP binding site [chemical binding]; other site
357544003749	Walker B motif; other site
357544003750	arginine finger; other site
357544003751	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
357544003752	prephenate dehydrogenase; Validated; Region: PRK08507
357544003753	Prephenate dehydrogenase; Region: PDH; pfam02153
357544003754	DNA/RNA endonuclease G, NUC1 [Nucleotide transport and metabolism]; Region: NUC1; COG1864
357544003755	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
357544003756	active site
357544003757	substrate binding site [chemical binding]; other site
357544003758	Mg2+ binding site [ion binding]; other site
357544003759	Type III restriction/modification enzyme methylation subunit; Region: TypeIII_RM_meth; pfam12564
357544003760	DNA methylase; Region: N6_N4_Mtase; pfam01555
357544003761	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
357544003762	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
357544003763	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3421
357544003764	ATP binding site [chemical binding]; other site
357544003765	putative Mg++ binding site [ion binding]; other site
357544003766	biotin synthase; Provisional; Region: PRK08508
357544003767	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
357544003768	FeS/SAM binding site; other site
357544003769	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
357544003770	YihY family inner membrane protein; Region: yihY_not_rbn; TIGR00765
357544003771	Uncharacterized conserved protein [Function unknown]; Region: COG1479
357544003772	Protein of unknown function DUF262; Region: DUF262; pfam03235
357544003773	Protein of unknown function DUF262; Region: DUF262; pfam03235
357544003774	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
357544003775	7-cyano-7-deazaguanine reductase; Region: QueF-II; TIGR03139
357544003776	Uncharacterized homolog of plant Iojap protein [Function unknown]; Region: COG0799
357544003777	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
357544003778	tRNA dimethylallyltransferase; Region: miaA; TIGR00174
357544003779	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
357544003780	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
357544003781	Ligand binding site; other site
357544003782	metal-binding site
357544003783	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
357544003784	Sulfatase; Region: Sulfatase; pfam00884
357544003785	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13904
357544003786	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
357544003787	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
357544003788	flagellum-specific ATP synthase; Validated; Region: fliI; PRK08472
357544003789	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
357544003790	Walker A motif/ATP binding site; other site
357544003791	Walker B motif; other site
357544003792	Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis [Cell motility and secretion / Intracellular trafficking and secretion]; Region: VirB11; COG0630
357544003793	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
357544003794	ATP binding site [chemical binding]; other site
357544003795	Walker A motif; other site
357544003796	hexamer interface [polypeptide binding]; other site
357544003797	Walker B motif; other site
357544003798	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
357544003799	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
357544003800	active site
357544003801	HIGH motif; other site
357544003802	nucleotide binding site [chemical binding]; other site
357544003803	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
357544003804	active site
357544003805	KMSKS motif; other site
357544003806	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
357544003807	tRNA binding surface [nucleotide binding]; other site
357544003808	anticodon binding site; other site
357544003809	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
357544003810	RNA binding surface [nucleotide binding]; other site
357544003811	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544003812	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14462
357544003813	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
357544003814	FeS/SAM binding site; other site
357544003815	KpsF/GutQ family protein; Region: kpsF; TIGR00393
357544003816	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
357544003817	putative active site [active]
357544003818	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
357544003819	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
357544003820	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
357544003821	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
357544003822	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
357544003823	dimethyladenosine transferase; Region: ksgA; TIGR00755
357544003824	formyltetrahydrofolate deformylase; Region: PurU; TIGR00655
357544003825	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
357544003826	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
357544003827	active site
357544003828	substrate binding site [chemical binding]; other site
357544003829	cosubstrate binding site; other site
357544003830	catalytic site [active]
357544003831	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
357544003832	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
357544003833	tandem repeat interface [polypeptide binding]; other site
357544003834	oligomer interface [polypeptide binding]; other site
357544003835	active site residues [active]
357544003836	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
357544003837	active site
357544003838	carbon storage regulator; Provisional; Region: PRK00568
357544003839	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: PRK04181
357544003840	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
357544003841	SmpB-tmRNA interface; other site
357544003842	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; pfam01618
357544003843	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
357544003844	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
357544003845	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
357544003846	ribonuclease P protein component, eubacterial; Region: rnpA; TIGR00188
357544003847	hypothetical protein; Provisional; Region: PRK14374
357544003848	membrane protein insertase; Provisional; Region: PRK01318
357544003849	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
357544003850	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
357544003851	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
357544003852	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
357544003853	tRNA modification GTPase TrmE; Region: mnmE_trmE_thdF; TIGR00450
357544003854	Circularly permuted YlqF-related GTPases; Region: YlqF_related_GTPase; cl17249
357544003855	GTP/Mg2+ binding site [chemical binding]; other site
357544003856	G4 box; other site
357544003857	G5 box; other site
357544003858	trmE is a tRNA modification GTPase; Region: trmE; cd04164
357544003859	G1 box; other site
357544003860	G1 box; other site
357544003861	GTP/Mg2+ binding site [chemical binding]; other site
357544003862	Switch I region; other site
357544003863	Switch I region; other site
357544003864	G2 box; other site
357544003865	G2 box; other site
357544003866	Switch II region; other site
357544003867	G3 box; other site
357544003868	G3 box; other site
357544003869	Switch II region; other site
357544003870	G4 box; other site
357544003871	G5 box; other site
357544003872	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
357544003873	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544003874	DC-EC Repeat; Region: CagY_M; pfam07337
357544003875	Predicted alternative thymidylate synthase [Nucleotide transport and metabolism]; Region: THY1; COG1351
357544003876	glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Region: glmS; TIGR01135
357544003877	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
357544003878	glutaminase active site [active]
357544003879	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
357544003880	dimer interface [polypeptide binding]; other site
357544003881	active site
357544003882	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
357544003883	dimer interface [polypeptide binding]; other site
357544003884	active site
357544003885	Protein of unknown function (DUF2443); Region: DUF2443; pfam10398
357544003886	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
357544003887	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
357544003888	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
357544003889	Walker A motif; other site
357544003890	ATP binding site [chemical binding]; other site
357544003891	Walker B motif; other site
357544003892	arginine finger; other site
357544003893	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
357544003894	DnaA box-binding interface [nucleotide binding]; other site
357544003895	Human Ape1-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Ape1-like_AP-endo; cd09087
357544003896	active site
357544003897	putative catalytic site [active]
357544003898	DNA binding site [nucleotide binding]
357544003899	putative phosphate binding site [ion binding]; other site
357544003900	metal binding site A [ion binding]; metal-binding site
357544003901	AP binding site [nucleotide binding]; other site
357544003902	metal binding site B [ion binding]; metal-binding site
357544003903	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544003904	ATP-dependent DNA helicase RecG; Region: recG; TIGR00643
357544003905	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
357544003906	ssDNA binding site; other site
357544003907	generic binding surface II; other site
357544003908	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
357544003909	ATP binding site [chemical binding]; other site
357544003910	putative Mg++ binding site [ion binding]; other site
357544003911	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
357544003912	nucleotide binding region [chemical binding]; other site
357544003913	ATP-binding site [chemical binding]; other site
357544003914	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
357544003915	DNA methylase; Region: N6_N4_Mtase; cl17433
357544003916	DNA methylase; Region: N6_N4_Mtase; pfam01555
357544003917	DNA methylase; Region: N6_N4_Mtase; pfam01555
357544003918	Restriction endonuclease [Defense mechanisms]; Region: COG3587
357544003919	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
357544003920	ATP binding site [chemical binding]; other site
357544003921	putative Mg++ binding site [ion binding]; other site
357544003922	Type II restriction enzyme, methylase subunits [Defense mechanisms]; Region: COG1002
357544003923	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
357544003924	TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950
357544003925	transcription elongation factor NusA; Provisional; Region: nusA; PRK12328
357544003926	NusA N-terminal domain; Region: NusA_N; pfam08529
357544003927	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
357544003928	RNA binding site [nucleotide binding]; other site
357544003929	homodimer interface [polypeptide binding]; other site
357544003930	NusA-like KH domain; Region: KH_5; pfam13184
357544003931	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
357544003932	G-X-X-G motif; other site
357544003933	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
357544003934	L-seryl-tRNA selenium transferase; Region: SelA; pfam03841
357544003935	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
357544003936	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
357544003937	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
357544003938	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
357544003939	TonB-dependent Receptor Plug Domain; Region: Plug; cl08461
357544003940	FolB domain; Region: folB_dom; TIGR00526
357544003941	active site
357544003942	acyl-phosphate glycerol 3-phosphate acyltransferase; Region: TIGR00023
357544003943	cytochrome c oxidase accessory protein FixG; Region: ccoG_rdxA_fixG; TIGR02745
357544003944	4Fe-4S binding domain; Region: Fer4_5; pfam12801
357544003945	Ubp3 associated protein Bre5; Region: Bre5; pfam11614
357544003946	Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism]; Region: LYS9; COG1748
357544003947	NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226
357544003948	NAD(P) binding pocket [chemical binding]; other site
357544003949	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
357544003950	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
357544003951	catalytic motif [active]
357544003952	Zn binding site [ion binding]; other site
357544003953	Pyrimidine reductase, riboflavin biosynthesis [Coenzyme metabolism]; Region: RibD; COG1985
357544003954	RibD C-terminal domain; Region: RibD_C; cl17279
357544003955	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
357544003956	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
357544003957	Putative metal-binding domain of cation transport ATPase; Region: ATPase-cat_bd; pfam12156
357544003958	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
357544003959	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
357544003960	metal-binding site [ion binding]
357544003961	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
357544003962	Soluble P-type ATPase [General function prediction only]; Region: COG4087
357544003963	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3399
357544003964	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544003965	AlwI restriction endonuclease; Region: RE_AlwI; pfam09491
357544003966	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
357544003967	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG3392
357544003968	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
357544003969	Predicted permeases [General function prediction only]; Region: COG0795
357544003970	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
357544003971	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
357544003972	putative active site [active]
357544003973	catalytic residue [active]
357544003974	ribosomal protein L25, Ctc-form; Region: ctc_TL5; TIGR00731
357544003975	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
357544003976	5S rRNA interface [nucleotide binding]; other site
357544003977	CTC domain interface [polypeptide binding]; other site
357544003978	L16 interface [polypeptide binding]; other site
357544003979	Transaldolase-like proteins from plants and bacteria; Region: Transaldolase_like; cd00955
357544003980	putative active site [active]
357544003981	transaldolase; Provisional; Region: PRK03903
357544003982	catalytic residue [active]
357544003983	UDP-N-acetylmuramyl-tripeptide synthetase; Region: murE; TIGR01085
357544003984	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
357544003985	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
357544003986	NifU-like domain; Region: NifU; pfam01106
357544003987	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
357544003988	Phosphate transporter family; Region: PHO4; pfam01384
357544003989	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
357544003990	Domain of unknown function DUF21; Region: DUF21; pfam01595
357544003991	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
357544003992	Transporter associated domain; Region: CorC_HlyC; smart01091
357544003993	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
357544003994	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
357544003995	HlyD family secretion protein; Region: HlyD_3; pfam13437
357544003996	ABC-2 type transporter; Region: ABC2_membrane; cl17235
357544003997	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
357544003998	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
357544003999	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
357544004000	uncharacterized protein, YigZ family; Region: IMPACT_YIGZ; TIGR00257
357544004001	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
357544004002	Uncharacterized protein family (UPF0093); Region: UPF0093; cl00863
357544004003	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
357544004004	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
357544004005	S-adenosylmethionine binding site [chemical binding]; other site
357544004006	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK14065
357544004007	Predicted amidohydrolase [General function prediction only]; Region: COG0388
357544004008	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cd07197
357544004009	active site
357544004010	catalytic triad [active]
357544004011	dimer interface [polypeptide binding]; other site
357544004012	seryl-tRNA synthetase; Provisional; Region: PRK05431
357544004013	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
357544004014	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
357544004015	dimer interface [polypeptide binding]; other site
357544004016	active site
357544004017	motif 1; other site
357544004018	motif 2; other site
357544004019	motif 3; other site
357544004020	TPR repeat; Region: TPR_11; pfam13414
357544004021	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
357544004022	TPR motif; other site
357544004023	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
357544004024	binding surface
357544004025	TPR motif; other site
357544004026	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
357544004027	Part of AAA domain; Region: AAA_19; pfam13245
357544004028	Family description; Region: UvrD_C_2; pfam13538
357544004029	flagellar basal body P-ring biosynthesis protein FlgA; Reviewed; Region: flgA; PRK08515
357544004030	flagella basal body P-ring formation protein FlgA; Region: flgA_cterm; TIGR03170
357544004031	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
357544004032	Flavoprotein; Region: Flavoprotein; pfam02441
357544004033	Phosphopantetheine adenylyltransferase [Coenzyme metabolism]; Region: CoaD; COG0669
357544004034	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
357544004035	active site
357544004036	(T/H)XGH motif; other site
357544004037	thymidylate kinase; Validated; Region: tmk; PRK00698
357544004038	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
357544004039	TMP-binding site; other site
357544004040	ATP-binding site [chemical binding]; other site
357544004041	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
357544004042	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
357544004043	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
357544004044	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
357544004045	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
357544004046	DNA polymerase I; Region: pola; TIGR00593
357544004047	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
357544004048	active site
357544004049	metal binding site 1 [ion binding]; metal-binding site
357544004050	putative 5' ssDNA interaction site; other site
357544004051	metal binding site 3; metal-binding site
357544004052	metal binding site 2 [ion binding]; metal-binding site
357544004053	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
357544004054	putative DNA binding site [nucleotide binding]; other site
357544004055	putative metal binding site [ion binding]; other site
357544004056	3'-5' exonuclease; Region: 35EXOc; smart00474
357544004057	active site
357544004058	substrate binding site [chemical binding]; other site
357544004059	catalytic site [active]
357544004060	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
357544004061	active site
357544004062	DNA binding site [nucleotide binding]
357544004063	catalytic site [active]
357544004064	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544004065	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
357544004066	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
357544004067	homodimer interface [polypeptide binding]; other site
357544004068	substrate-cofactor binding pocket; other site
357544004069	catalytic residue [active]
357544004070	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544004071	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
357544004072	conserved hypothetical integral membrane protein; Region: TIGR00056
357544004073	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
357544004074	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
357544004075	Walker A/P-loop; other site
357544004076	ATP binding site [chemical binding]; other site
357544004077	Q-loop/lid; other site
357544004078	ABC transporter signature motif; other site
357544004079	Walker B; other site
357544004080	D-loop; other site
357544004081	H-loop/switch region; other site
357544004082	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
357544004083	mce related protein; Region: MCE; pfam02470
357544004084	Heat shock protein [Posttranslational modification, protein turnover, chaperones]; Region: HslJ; COG3187
357544004085	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
357544004086	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113
357544004087	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
357544004088	active site
357544004089	PHP Thumb interface [polypeptide binding]; other site
357544004090	metal binding site [ion binding]; metal-binding site
357544004091	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
357544004092	generic binding surface I; other site
357544004093	generic binding surface II; other site
357544004094	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
357544004095	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
357544004096	RNA binding surface [nucleotide binding]; other site
357544004097	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
357544004098	active site
357544004099	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
357544004100	catalytic residues [active]
357544004101	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
357544004102	LPP20 lipoprotein; Region: LPP20; pfam02169
357544004103	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
357544004104	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
357544004105	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
357544004106	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
357544004107	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
357544004108	HsdM N-terminal domain; Region: HsdM_N; pfam12161
357544004109	type I site-specific deoxyribonuclease, HsdR family; Region: hsdR; TIGR00348
357544004110	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
357544004111	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
357544004112	ATP binding site [chemical binding]; other site
357544004113	putative Mg++ binding site [ion binding]; other site
357544004114	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
357544004115	Protein of unknown function DUF45; Region: DUF45; pfam01863
357544004116	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
357544004117	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
357544004118	N-terminal plug; other site
357544004119	ligand-binding site [chemical binding]; other site
357544004120	Arginase family; Region: Arginase; cd09989
357544004121	active site
357544004122	Mn binding site [ion binding]; other site
357544004123	oligomer interface [polypeptide binding]; other site
357544004124	S-methylmethionine transporter; Provisional; Region: PRK11387
357544004125	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
357544004126	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
357544004127	hexamer interface [polypeptide binding]; other site
357544004128	ligand binding site [chemical binding]; other site
357544004129	putative active site [active]
357544004130	NAD(P) binding site [chemical binding]; other site
357544004131	Uncharacterized conserved protein [Function unknown]; Region: COG1479
357544004132	Protein of unknown function DUF262; Region: DUF262; pfam03235
357544004133	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
357544004134	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
357544004135	NAD kinase [Coenzyme metabolism]; Region: nadF; COG0061
357544004136	ATP-NAD kinase; Region: NAD_kinase; pfam01513
357544004137	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
357544004138	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
357544004139	Walker A/P-loop; other site
357544004140	ATP binding site [chemical binding]; other site
357544004141	Q-loop/lid; other site
357544004142	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
357544004143	ABC transporter signature motif; other site
357544004144	Walker B; other site
357544004145	D-loop; other site
357544004146	H-loop/switch region; other site
357544004147	Predicted RNA-binding protein homologous to eukaryotic snRNP [Transcription]; Region: COG1293
357544004148	Domain of unknown function (DUF814); Region: DUF814; pfam05670
357544004149	DNA polymerase III subunit epsilon; Provisional; Region: PRK08517
357544004150	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
357544004151	active site
357544004152	catalytic site [active]
357544004153	substrate binding site [chemical binding]; other site
357544004154	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
357544004155	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
357544004156	substrate binding site [chemical binding]; other site
357544004157	hexamer interface [polypeptide binding]; other site
357544004158	metal binding site [ion binding]; metal-binding site
357544004159	FIG, FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with various substrates. Fructose-1,6-bisphospatase (both the major and the glpX-encoded variant) hydrolyze fructose-1,6,-bisphosphate to fructose-6-phosphate in...; Region: FIG; cl00289
357544004160	active site
357544004161	Methyltransferase domain; Region: Methyltransf_26; pfam13659
357544004162	Cytochrome c1 [Energy production and conversion]; Region: CYT1; COG2857
357544004163	Cytochrome c; Region: Cytochrom_C; pfam00034
357544004164	Cytochrome c; Region: Cytochrom_C; cl11414
357544004165	Cytochrome b subunit of the bc complex [Energy production and conversion]; Region: QcrB; COG1290
357544004166	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cd00284
357544004167	intrachain domain interface; other site
357544004168	interchain domain interface [polypeptide binding]; other site
357544004169	heme bH binding site [chemical binding]; other site
357544004170	Qi binding site; other site
357544004171	heme bL binding site [chemical binding]; other site
357544004172	Qo binding site; other site
357544004173	interchain domain interface [polypeptide binding]; other site
357544004174	intrachain domain interface; other site
357544004175	Qi binding site; other site
357544004176	Cytochrome b(C-terminal)/b6/petD; Region: Cytochrom_B_C; pfam00032
357544004177	Qo binding site; other site
357544004178	ubiquinol-cytochrome c reductase, iron-sulfur subunit; Region: Rieske_proteo; TIGR01416
357544004179	Iron-sulfur protein (ISP) component of the bc(1) complex family, Rieske domain; The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. The bc(1) complex is a multisubunit enzyme found in many different organisms including...; Region: Rieske_cytochrome_bc1; cd03470
357544004180	[2Fe-2S] cluster binding site [ion binding]; other site
357544004181	transcription-repair coupling factor (mfd); Region: mfd; TIGR00580
357544004182	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
357544004183	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
357544004184	ATP binding site [chemical binding]; other site
357544004185	putative Mg++ binding site [ion binding]; other site
357544004186	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
357544004187	nucleotide binding region [chemical binding]; other site
357544004188	ATP-binding site [chemical binding]; other site
357544004189	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
357544004190	Integral membrane protein CcmA involved in cell shape determination [Cell envelope biogenesis, outer membrane]; Region: CcmA; COG1664
357544004191	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
357544004192	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
357544004193	Peptidase family M23; Region: Peptidase_M23; pfam01551
357544004194	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
357544004195	Peptidase family M23; Region: Peptidase_M23; pfam01551
357544004196	folylpolyglutamate synthase/dihydrofolate synthase; Region: folC; TIGR01499
357544004197	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
357544004198	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
357544004199	Lipopolysaccharide-assembly; Region: LptE; pfam04390
357544004200	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
357544004201	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
357544004202	HIGH motif; other site
357544004203	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
357544004204	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
357544004205	active site
357544004206	KMSKS motif; other site
357544004207	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
357544004208	tRNA binding surface [nucleotide binding]; other site
357544004209	anticodon binding site; other site
357544004210	protein-export membrane protein SecF; Region: 3a0501s07; TIGR00966
357544004211	Protein export membrane protein; Region: SecD_SecF; pfam02355
357544004212	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
357544004213	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
357544004214	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
357544004215	pH-dependent sodium/proton antiporter; Provisional; Region: nhaA; PRK14856
357544004216	putative recombination protein RecB; Provisional; Region: PRK13909
357544004217	Family description; Region: UvrD_C_2; pfam13538
357544004218	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
357544004219	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
357544004220	rRNA interaction site [nucleotide binding]; other site
357544004221	S8 interaction site; other site
357544004222	putative laminin-1 binding site; other site
357544004223	elongation factor Ts; Provisional; Region: tsf; PRK09377
357544004224	UBA/TS-N domain; Region: UBA; pfam00627
357544004225	Elongation factor TS; Region: EF_TS; pfam00889
357544004226	Elongation factor TS; Region: EF_TS; pfam00889
357544004227	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
357544004228	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
357544004229	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
357544004230	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK03907
357544004231	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
357544004232	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
357544004233	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
357544004234	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
357544004235	Cell cycle protein; Region: FTSW_RODA_SPOVE; pfam01098
357544004236	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
357544004237	Periplasmic binding protein TroA_d.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_d; cd01141
357544004238	putative ligand binding site [chemical binding]; other site
357544004239	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
357544004240	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
357544004241	intersubunit interface [polypeptide binding]; other site
357544004242	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
357544004243	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
357544004244	dimer interface [polypeptide binding]; other site
357544004245	decamer (pentamer of dimers) interface [polypeptide binding]; other site
357544004246	catalytic triad [active]
357544004247	peroxidatic and resolving cysteines [active]
357544004248	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
357544004249	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
357544004250	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
357544004251	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
357544004252	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
357544004253	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
357544004254	G1 box; other site
357544004255	GTP/Mg2+ binding site [chemical binding]; other site
357544004256	Switch I region; other site
357544004257	G2 box; other site
357544004258	G3 box; other site
357544004259	Switch II region; other site
357544004260	G4 box; other site
357544004261	G5 box; other site
357544004262	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1934
357544004263	OstA-like protein; Region: OstA; pfam03968
357544004264	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
357544004265	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
357544004266	motif II; other site
357544004267	Lipoproteins [Cell envelope biogenesis, outer membrane]; Region: RlpA; COG0797
357544004268	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
357544004269	Sporulation related domain; Region: SPOR; pfam05036
357544004270	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
357544004271	N-acetyl-D-glucosamine binding site [chemical binding]; other site
357544004272	catalytic residue [active]
357544004273	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
357544004274	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
357544004275	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
357544004276	active site
357544004277	riboflavin synthase, alpha subunit; Region: ribE; TIGR00187
357544004278	Lumazine binding domain; Region: Lum_binding; pfam00677
357544004279	Lumazine binding domain; Region: Lum_binding; pfam00677
357544004280	flhB C-terminus-related protein; Region: flhB_rel; TIGR00789
357544004281	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
357544004282	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
357544004283	Walker A/P-loop; other site
357544004284	ATP binding site [chemical binding]; other site
357544004285	Q-loop/lid; other site
357544004286	ABC transporter signature motif; other site
357544004287	Walker B; other site
357544004288	D-loop; other site
357544004289	H-loop/switch region; other site
357544004290	NIL domain; Region: NIL; pfam09383
357544004291	ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism]; Region: AbcD; COG2011
357544004292	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
357544004293	PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_5; cd03394
357544004294	active site
357544004295	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
357544004296	This subfamily is composed of uncharacterized bacterial glycosyltransferases in the MraY-like family. This family contains both eukaryotic and prokaryotic UDP-D-N-acetylhexosamine:polyprenol phosphate D-N-acetylhexosamine-1-phosphate transferases, which...; Region: GT_MraY_like; cd06912
357544004297	Mg++ binding site [ion binding]; other site
357544004298	putative catalytic motif [active]
357544004299	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
357544004300	active site
357544004301	hydrophilic channel; other site
357544004302	dimerization interface [polypeptide binding]; other site
357544004303	catalytic residues [active]
357544004304	active site lid [active]
357544004305	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
357544004306	4-hydroxythreonine-4-phosphate dehydrogenase; Provisional; Region: pdxA; PRK03946
357544004307	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
357544004308	metallohydrolase, glycoprotease/Kae1 family; Region: gcp_kae1; TIGR00329
357544004309	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
357544004310	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
357544004311	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
357544004312	hypothetical protein; Provisional; Region: PRK10236
357544004313	Domain of unknown function (DUF3944); Region: DUF3944; pfam13099
357544004314	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735
357544004315	Initiator Replication protein; Region: Rep_3; pfam01051
357544004316	Fic family protein [Function unknown]; Region: COG3177
357544004317	Fic/DOC family; Region: Fic; pfam02661
357544004318	Initiator Replication protein; Region: Rep_3; pfam01051
357544004319	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
357544004320	Bacterial mobilisation protein (MobC); Region: MobC; pfam05713
357544004321	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041; cl17396