-- dump date   	20140619_113909
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1055529000001	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
1055529000002	putative RNA binding site [nucleotide binding]; other site
1055529000003	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
1055529000004	homopentamer interface [polypeptide binding]; other site
1055529000005	active site
1055529000006	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
1055529000007	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeB; cd00884
1055529000008	active site clefts [active]
1055529000009	zinc binding site [ion binding]; other site
1055529000010	dimer interface [polypeptide binding]; other site
1055529000011	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
1055529000012	active site
1055529000013	dimer interface [polypeptide binding]; other site
1055529000014	pantoate--beta-alanine ligase; Region: panC; TIGR00018
1055529000015	Pantoate-beta-alanine ligase; Region: PanC; cd00560
1055529000016	active site
1055529000017	ATP-binding site [chemical binding]; other site
1055529000018	pantoate-binding site; other site
1055529000019	HXXH motif; other site
1055529000020	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529000021	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
1055529000022	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1055529000023	ring oligomerisation interface [polypeptide binding]; other site
1055529000024	ATP/Mg binding site [chemical binding]; other site
1055529000025	stacking interactions; other site
1055529000026	hinge regions; other site
1055529000027	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1055529000028	oligomerisation interface [polypeptide binding]; other site
1055529000029	mobile loop; other site
1055529000030	roof hairpin; other site
1055529000031	DNA primase, catalytic core; Region: dnaG; TIGR01391
1055529000032	CHC2 zinc finger; Region: zf-CHC2; pfam01807
1055529000033	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1055529000034	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1055529000035	active site
1055529000036	metal binding site [ion binding]; metal-binding site
1055529000037	interdomain interaction site; other site
1055529000038	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
1055529000039	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
1055529000040	Ligand Binding Site [chemical binding]; other site
1055529000041	TrbC/VIRB2 family; Region: TrbC; cl01583
1055529000042	type IV secretion/conjugal transfer ATPase, VirB4 family; Region: VirB4_CagE; TIGR00929
1055529000043	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
1055529000044	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1055529000045	Walker A motif; other site
1055529000046	ATP binding site [chemical binding]; other site
1055529000047	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1055529000048	Walker B motif; other site
1055529000049	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3014
1055529000050	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cd00588
1055529000051	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1055529000052	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1055529000053	active site
1055529000054	phosphorylation site [posttranslational modification]
1055529000055	intermolecular recognition site; other site
1055529000056	dimerization interface [polypeptide binding]; other site
1055529000057	carboxynorspermidine decarboxylase; Region: nspC; TIGR01047
1055529000058	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Carboxynorspermidine Decarboxylase; Region: PLPDE_III_CANSDC; cd06829
1055529000059	dimer interface [polypeptide binding]; other site
1055529000060	active site
1055529000061	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1055529000062	catalytic residues [active]
1055529000063	substrate binding site [chemical binding]; other site
1055529000064	lipid A 1-phosphatase; Reviewed; Region: PRK09597
1055529000065	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1055529000066	active site
1055529000067	lipid A phosphoethanolamine transferase; Reviewed; Region: PRK09598
1055529000068	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1055529000069	Sulfatase; Region: Sulfatase; pfam00884
1055529000070	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529000071	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
1055529000072	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
1055529000073	dimer interface [polypeptide binding]; other site
1055529000074	active site
1055529000075	citrylCoA binding site [chemical binding]; other site
1055529000076	NADH binding [chemical binding]; other site
1055529000077	cationic pore residues; other site
1055529000078	oxalacetate/citrate binding site [chemical binding]; other site
1055529000079	coenzyme A binding site [chemical binding]; other site
1055529000080	catalytic triad [active]
1055529000081	isocitrate dehydrogenase; Validated; Region: PRK07362
1055529000082	isocitrate dehydrogenase; Reviewed; Region: PRK07006
1055529000083	Protein of unknown function (DUF1523); Region: DUF1523; pfam07509
1055529000084	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
1055529000085	AAA domain; Region: AAA_26; pfam13500
1055529000086	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1055529000087	Ligand Binding Site [chemical binding]; other site
1055529000088	Uncharacterized conserved protein [Function unknown]; Region: COG2127
1055529000089	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
1055529000090	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1055529000091	Walker A motif; other site
1055529000092	ATP binding site [chemical binding]; other site
1055529000093	Walker B motif; other site
1055529000094	arginine finger; other site
1055529000095	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1055529000096	Walker A motif; other site
1055529000097	ATP binding site [chemical binding]; other site
1055529000098	Walker B motif; other site
1055529000099	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1055529000100	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
1055529000101	tetramerization interface [polypeptide binding]; other site
1055529000102	active site
1055529000103	hypothetical protein; Provisional; Region: PRK03762
1055529000104	PDZ domain; Region: PDZ_2; pfam13180
1055529000105	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
1055529000106	Type IV secretory pathway, TrbL components [Intracellular trafficking and secretion]; Region: TrbL; COG3846
1055529000107	Type IV secretory pathway, component VirB8 [Intracellular trafficking and secretion]; Region: VirB8; COG3736
1055529000108	Type IV secretory pathway, VirB9 components [Intracellular trafficking and secretion]; Region: VirB9; COG3504
1055529000109	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911
1055529000110	VirB7 interaction site; other site
1055529000111	Type IV secretory pathway, VirB10 components [Intracellular trafficking and secretion]; Region: VirB10; COG2948
1055529000112	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
1055529000113	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
1055529000114	Substrate binding site; other site
1055529000115	Cupin domain; Region: Cupin_2; cl17218
1055529000116	GDP-mannose 4,6-dehydratase; Region: gmd; TIGR01472
1055529000117	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
1055529000118	NADP-binding site; other site
1055529000119	homotetramer interface [polypeptide binding]; other site
1055529000120	substrate binding site [chemical binding]; other site
1055529000121	homodimer interface [polypeptide binding]; other site
1055529000122	active site
1055529000123	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
1055529000124	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
1055529000125	NADP binding site [chemical binding]; other site
1055529000126	active site
1055529000127	putative substrate binding site [chemical binding]; other site
1055529000128	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
1055529000129	dimerization interface [polypeptide binding]; other site
1055529000130	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
1055529000131	ATP binding site [chemical binding]; other site
1055529000132	Acylphosphatase; Region: Acylphosphatase; pfam00708
1055529000133	[NiFe] hydrogenase maturation protein HypF; Region: hypF; TIGR00143
1055529000134	HypF finger; Region: zf-HYPF; pfam07503
1055529000135	HypF finger; Region: zf-HYPF; pfam07503
1055529000136	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
1055529000137	Peptidylarginine deiminase and related enzymes [Amino acid transport and metabolism]; Region: COG2957
1055529000138	Porphyromonas-type peptidyl-arginine deiminase; Region: PAD_porph; pfam04371
1055529000139	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1055529000140	DNA methylase; Region: N6_N4_Mtase; pfam01555
1055529000141	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
1055529000142	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1055529000143	cofactor binding site; other site
1055529000144	DNA binding site [nucleotide binding]
1055529000145	substrate interaction site [chemical binding]; other site
1055529000146	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1055529000147	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1055529000148	active site
1055529000149	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
1055529000150	DNA methylase; Region: N6_N4_Mtase; pfam01555
1055529000151	Tsp45I type II restriction enzyme; Region: Tsp45I; pfam06300
1055529000152	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
1055529000153	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1055529000154	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
1055529000155	Na binding site [ion binding]; other site
1055529000156	Proline dehydrogenase; Region: Pro_dh; pfam01619
1055529000157	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
1055529000158	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1055529000159	Glutamate binding site [chemical binding]; other site
1055529000160	NAD binding site [chemical binding]; other site
1055529000161	catalytic residues [active]
1055529000162	Protein of unknown function (DUF972); Region: DUF972; pfam06156
1055529000163	SH3 domain protein; Region: SH3_and_anchor; TIGR04211
1055529000164	Proteins of 100 residues with WXG; Region: WXG100; cl02005
1055529000165	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
1055529000166	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
1055529000167	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1055529000168	Urease accessory protein UreH [Posttranslational modification, protein turnover, chaperones]; Region: UreH; COG0829
1055529000169	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
1055529000170	G1 box; other site
1055529000171	GTP/Mg2+ binding site [chemical binding]; other site
1055529000172	G2 box; other site
1055529000173	Switch I region; other site
1055529000174	G3 box; other site
1055529000175	Switch II region; other site
1055529000176	G4 box; other site
1055529000177	G5 box; other site
1055529000178	Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones]; Region: UreF; COG0830
1055529000179	UreF; Region: UreF; pfam01730
1055529000180	urease accessory protein UreE; Provisional; Region: ureE; PRK13261
1055529000181	UreE urease accessory protein. UreE is a metallochaperone assisting the insertion of a Ni2+ ion in the active site of urease, an important step in the in vivo assembly of urease, an enzyme that hydrolyses urea into ammonia and carbamic acid. The...; Region: UreE; cd00571
1055529000182	dimer interface [polypeptide binding]; other site
1055529000183	catalytic residues [active]
1055529000184	AmiS/UreI family transporter; Region: AmiS_UreI; pfam02293
1055529000185	urease subunit beta; Provisional; Region: ureB; PRK13985
1055529000186	Urease alpha-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, fungi and plants. Their primary role is to allow the use of...; Region: Urease_alpha; cd00375
1055529000187	subunit interactions [polypeptide binding]; other site
1055529000188	active site
1055529000189	flap region; other site
1055529000190	urease subunit alpha; Provisional; Region: PRK13986
1055529000191	Urease gamma-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use...; Region: Urease_gamma; cd00390
1055529000192	alpha-gamma subunit interface [polypeptide binding]; other site
1055529000193	beta-gamma subunit interface [polypeptide binding]; other site
1055529000194	Urease beta-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use of...; Region: Urease_beta; cd00407
1055529000195	gamma-beta subunit interface [polypeptide binding]; other site
1055529000196	alpha-beta subunit interface [polypeptide binding]; other site
1055529000197	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
1055529000198	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14324
1055529000199	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
1055529000200	active site
1055529000201	substrate binding site [chemical binding]; other site
1055529000202	metal binding site [ion binding]; metal-binding site
1055529000203	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1055529000204	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1055529000205	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1055529000206	RF-1 domain; Region: RF-1; pfam00472
1055529000207	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529000208	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1055529000209	dimer interface [polypeptide binding]; other site
1055529000210	putative CheW interface [polypeptide binding]; other site
1055529000211	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1055529000212	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1055529000213	23S rRNA interface [nucleotide binding]; other site
1055529000214	L3 interface [polypeptide binding]; other site
1055529000215	Malate:quinone oxidoreductase (Mqo); Region: Mqo; cl17341
1055529000216	Predicted dehydrogenase [General function prediction only]; Region: COG0579
1055529000217	NLPC_P60 stabilising domain, N term; Region: N_NLPC_P60; pfam12912
1055529000218	SH3 domain of the SH3b1 type; Region: SH3_6; pfam12913
1055529000219	SH3 domain of SH3b2 type; Region: SH3_7; pfam12914
1055529000220	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1055529000221	NlpC/P60 family; Region: NLPC_P60; pfam00877
1055529000222	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
1055529000223	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1055529000224	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1055529000225	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1055529000226	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1055529000227	DNA binding residues [nucleotide binding]
1055529000228	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
1055529000229	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
1055529000230	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1055529000231	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1055529000232	potential protein location (hypothetical protein HPPN135_00460 [Helicobacter pylori Puno135]) that overlaps RNA (tRNA-S)
1055529000233	DpnII restriction endonuclease; Region: DpnII; pfam04556
1055529000234	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1055529000235	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1055529000236	DNA methylase; Region: N6_N4_Mtase; pfam01555
1055529000237	potential frameshift: common BLAST hit: gi|188526899|ref|YP_001909586.1| alpha-1,2-fucosyltransferase
1055529000238	2-hydroxyacid dehydrogenase; Provisional; Region: PRK08410
1055529000239	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_4; cd12162
1055529000240	putative ligand binding site [chemical binding]; other site
1055529000241	putative NAD binding site [chemical binding]; other site
1055529000242	catalytic site [active]
1055529000243	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
1055529000244	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
1055529000245	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1055529000246	catalytic residue [active]
1055529000247	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1055529000248	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1055529000249	dimer interface [polypeptide binding]; other site
1055529000250	putative CheW interface [polypeptide binding]; other site
1055529000251	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases and ATP sulphurylases. The domain forms a apha/beta/apha fold which  binds to Adenosine group; Region: Alpha_ANH_like; cd01986
1055529000252	Ligand Binding Site [chemical binding]; other site
1055529000253	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529000254	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1055529000255	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
1055529000256	metal-binding site
1055529000257	Cache is an extracellular domain that is predicted to have a role in small-molecule recognition in a wide range of proteins; Region: Cache_2; smart01049
1055529000258	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; Region: HAMP; smart00304
1055529000259	dimerization interface [polypeptide binding]; other site
1055529000260	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1055529000261	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1055529000262	dimer interface [polypeptide binding]; other site
1055529000263	putative CheW interface [polypeptide binding]; other site
1055529000264	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
1055529000265	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
1055529000266	active site
1055529000267	metal binding site [ion binding]; metal-binding site
1055529000268	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1055529000269	S-ribosylhomocysteinase; Provisional; Region: PRK02260
1055529000270	cystathionine gamma-synthase/cystathionine beta-lyase; Validated; Region: PRK06176
1055529000271	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1055529000272	homodimer interface [polypeptide binding]; other site
1055529000273	substrate-cofactor binding pocket; other site
1055529000274	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1055529000275	catalytic residue [active]
1055529000276	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1055529000277	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1055529000278	dimer interface [polypeptide binding]; other site
1055529000279	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1055529000280	catalytic residue [active]
1055529000281	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1055529000282	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
1055529000283	nucleotide binding site [chemical binding]; other site
1055529000284	NEF interaction site [polypeptide binding]; other site
1055529000285	SBD interface [polypeptide binding]; other site
1055529000286	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
1055529000287	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1055529000288	dimer interface [polypeptide binding]; other site
1055529000289	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1055529000290	heat-inducible transcription repressor; Provisional; Region: PRK03911
1055529000291	hypothetical protein; Provisional; Region: PRK05834
1055529000292	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2604
1055529000293	flagellin B; Provisional; Region: PRK13588
1055529000294	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1055529000295	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
1055529000296	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
1055529000297	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1055529000298	DNA topoisomerase I; Validated; Region: PRK05582
1055529000299	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
1055529000300	active site
1055529000301	interdomain interaction site; other site
1055529000302	putative metal-binding site [ion binding]; other site
1055529000303	nucleotide binding site [chemical binding]; other site
1055529000304	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1055529000305	domain I; other site
1055529000306	DNA binding groove [nucleotide binding]
1055529000307	phosphate binding site [ion binding]; other site
1055529000308	domain II; other site
1055529000309	domain III; other site
1055529000310	nucleotide binding site [chemical binding]; other site
1055529000311	catalytic site [active]
1055529000312	domain IV; other site
1055529000313	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1055529000314	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1055529000315	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1055529000316	Fe-S oxidoreductases [Energy production and conversion]; Region: COG0731
1055529000317	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1055529000318	FeS/SAM binding site; other site
1055529000319	Helicobacter pylori protein of unknown function (DUF874); Region: DUF874; pfam05917
1055529000320	Helicobacter pylori protein of unknown function (DUF874); Region: DUF874; pfam05917
1055529000321	phosphoenolpyruvate synthase; Validated; Region: PRK06464
1055529000322	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
1055529000323	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1055529000324	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1055529000325	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK12305
1055529000326	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
1055529000327	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1055529000328	active site
1055529000329	dimer interface [polypeptide binding]; other site
1055529000330	motif 1; other site
1055529000331	motif 2; other site
1055529000332	motif 3; other site
1055529000333	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1055529000334	anticodon binding site; other site
1055529000335	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
1055529000336	translation initiation factor IF-3; Region: infC; TIGR00168
1055529000337	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1055529000338	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
1055529000339	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1055529000340	23S rRNA binding site [nucleotide binding]; other site
1055529000341	L21 binding site [polypeptide binding]; other site
1055529000342	L13 binding site [polypeptide binding]; other site
1055529000343	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529000344	Protein of unknown function (DUF1104); Region: DUF1104; pfam06518
1055529000345	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
1055529000346	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1055529000347	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1055529000348	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1055529000349	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
1055529000350	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase [Amino acid transport and metabolism]; Region: AroG; COG3200
1055529000351	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1055529000352	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
1055529000353	catalytic triad [active]
1055529000354	Uncharacterized conserved protein [Function unknown]; Region: COG1556
1055529000355	iron-sulfur cluster-binding protein; Region: TIGR00273
1055529000356	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
1055529000357	Domain of unknown function (DUF3390); Region: DUF3390; pfam11870
1055529000358	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1055529000359	Cysteine-rich domain; Region: CCG; pfam02754
1055529000360	Cysteine-rich domain; Region: CCG; pfam02754
1055529000361	L-lactate transport; Region: lctP; TIGR00795
1055529000362	L-lactate permease [Energy production and conversion]; Region: LldP; COG1620
1055529000363	L-lactate permease [Energy production and conversion]; Region: LldP; COG1620
1055529000364	L-lactate permease; Region: Lactate_perm; pfam02652
1055529000365	DNA glycosylase MutY; Provisional; Region: PRK13910
1055529000366	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1055529000367	minor groove reading motif; other site
1055529000368	helix-hairpin-helix signature motif; other site
1055529000369	substrate binding pocket [chemical binding]; other site
1055529000370	active site
1055529000371	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
1055529000372	DNA binding and oxoG recognition site [nucleotide binding]
1055529000373	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1055529000374	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1055529000375	transmembrane helices; other site
1055529000376	Heme-copper oxidase subunit I.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which catalyze the reduction of O2 and simultaneously pump protons across the membrane.  The superfamily is...; Region: Heme_Cu_Oxidase_I; cl00275
1055529000377	Low-spin heme binding site [chemical binding]; other site
1055529000378	Cytochrome C and Quinol oxidase polypeptide I; Region: COX1; pfam00115
1055529000379	D-pathway; other site
1055529000380	Putative water exit pathway; other site
1055529000381	Binuclear center (active site) [active]
1055529000382	K-pathway; other site
1055529000383	Putative proton exit pathway; other site
1055529000384	Cbb3-type cytochrome oxidase, cytochrome c subunit [Energy production and conversion]; Region: CcoO; COG2993
1055529000385	Cytochrome C oxidase, mono-heme subunit/FixO; Region: FixO; cl01130
1055529000386	cytochrome c oxidase, cbb3-type, CcoQ subunit, epsilon-Proteobacterial; Region: cbb3_Q_epsi; TIGR02736
1055529000387	cytochrome c oxidase, cbb3-type, subunit III; Region: ccoP; TIGR00782
1055529000388	Cytochrome c; Region: Cytochrom_C; pfam00034
1055529000389	Cytochrome c; Region: Cytochrom_C; pfam00034
1055529000390	Family of unknown function (DUF4006); Region: DUF4006; pfam13179
1055529000391	Predicted periplasmic solute-binding protein [General function prediction only]; Region: COG2107
1055529000392	recombinase A; Provisional; Region: recA; PRK09354
1055529000393	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1055529000394	hexamer interface [polypeptide binding]; other site
1055529000395	Walker A motif; other site
1055529000396	ATP binding site [chemical binding]; other site
1055529000397	Walker B motif; other site
1055529000398	enolase; Provisional; Region: eno; PRK00077
1055529000399	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
1055529000400	dimer interface [polypeptide binding]; other site
1055529000401	metal binding site [ion binding]; metal-binding site
1055529000402	substrate binding pocket [chemical binding]; other site
1055529000403	AMIN domain; Region: AMIN; pfam11741
1055529000404	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
1055529000405	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1055529000406	ADP binding site [chemical binding]; other site
1055529000407	magnesium binding site [ion binding]; other site
1055529000408	putative shikimate binding site; other site
1055529000409	Cache domain; Region: Cache_1; pfam02743
1055529000410	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
1055529000411	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
1055529000412	Ligand binding site; other site
1055529000413	metal-binding site
1055529000414	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1055529000415	Sel1-like repeats; Region: SEL1; smart00671
1055529000416	Sel1-like repeats; Region: SEL1; smart00671
1055529000417	Sel1-like repeats; Region: SEL1; smart00671
1055529000418	Sel1-like repeats; Region: SEL1; smart00671
1055529000419	Sel1-like repeats; Region: SEL1; smart00671
1055529000420	Sel1-like repeats; Region: SEL1; smart00671
1055529000421	hypothetical protein; Provisional; Region: PRK12378
1055529000422	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
1055529000423	dimer interface [polypeptide binding]; other site
1055529000424	active site
1055529000425	Schiff base residues; other site
1055529000426	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1055529000427	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; Region: HAMP; smart00304
1055529000428	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
1055529000429	dimer interface [polypeptide binding]; other site
1055529000430	phosphorylation site [posttranslational modification]
1055529000431	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1055529000432	ATP binding site [chemical binding]; other site
1055529000433	Mg2+ binding site [ion binding]; other site
1055529000434	G-X-G motif; other site
1055529000435	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1055529000436	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1055529000437	active site
1055529000438	phosphorylation site [posttranslational modification]
1055529000439	intermolecular recognition site; other site
1055529000440	dimerization interface [polypeptide binding]; other site
1055529000441	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1055529000442	DNA binding site [nucleotide binding]
1055529000443	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1055529000444	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1055529000445	Peptidase family U32; Region: Peptidase_U32; pfam01136
1055529000446	peptide chain release factor 2; Region: prfB; TIGR00020
1055529000447	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1055529000448	RF-1 domain; Region: RF-1; pfam00472
1055529000449	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
1055529000450	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
1055529000451	dimer interface [polypeptide binding]; other site
1055529000452	putative functional site; other site
1055529000453	putative MPT binding site; other site
1055529000454	Flagellar biosynthesis pathway, component FliR [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliR; COG1684
1055529000455	Etoposide-induced protein 2.4 (EI24); Region: EI24; pfam07264
1055529000456	peptidylprolyl isomerase; Provisional; Region: prsA; PRK00059
1055529000457	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1055529000458	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1055529000459	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1055529000460	intersubunit interface [polypeptide binding]; other site
1055529000461	active site
1055529000462	zinc binding site [ion binding]; other site
1055529000463	Na+ binding site [ion binding]; other site
1055529000464	elongation factor P; Validated; Region: PRK00529
1055529000465	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1055529000466	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1055529000467	RNA binding site [nucleotide binding]; other site
1055529000468	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1055529000469	RNA binding site [nucleotide binding]; other site
1055529000470	pseudaminic acid synthase; Region: PseI; TIGR03586
1055529000471	NeuB family; Region: NeuB; pfam03102
1055529000472	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
1055529000473	NeuB binding interface [polypeptide binding]; other site
1055529000474	putative substrate binding site [chemical binding]; other site
1055529000475	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1055529000476	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1055529000477	Walker A/P-loop; other site
1055529000478	ATP binding site [chemical binding]; other site
1055529000479	Q-loop/lid; other site
1055529000480	ABC transporter signature motif; other site
1055529000481	Walker B; other site
1055529000482	D-loop; other site
1055529000483	H-loop/switch region; other site
1055529000484	apolipoprotein N-acyltransferase; Reviewed; Region: PRK12291
1055529000485	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
1055529000486	active site
1055529000487	catalytic triad [active]
1055529000488	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
1055529000489	Colicin V production protein; Region: Colicin_V; pfam02674
1055529000490	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
1055529000491	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1055529000492	dimer interface [polypeptide binding]; other site
1055529000493	putative anticodon binding site; other site
1055529000494	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1055529000495	motif 1; other site
1055529000496	active site
1055529000497	motif 2; other site
1055529000498	motif 3; other site
1055529000499	serine hydroxymethyltransferase; Reviewed; Region: PRK13034
1055529000500	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1055529000501	dimer interface [polypeptide binding]; other site
1055529000502	active site
1055529000503	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1055529000504	folate binding site [chemical binding]; other site
1055529000505	Domain of unknown function (DUF1882); Region: DUF1882; pfam08966
1055529000506	AE_Prim_S_like: primase domain similar to that found in the small subunit of archaeal and eukaryotic (A/E) DNA primases. The replication machineries of A/Es are distinct from that of bacteria. Primases are DNA-dependent RNA polymerases which synthesis...; Region: AE_Prim_S_like; cl01287
1055529000507	Uncharacterized protein family, UPF0114; Region: UPF0114; cl01078
1055529000508	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
1055529000509	PLD-like domain; Region: PLDc_2; pfam13091
1055529000510	putative active site [active]
1055529000511	catalytic site [active]
1055529000512	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
1055529000513	PLD-like domain; Region: PLDc_2; pfam13091
1055529000514	putative active site [active]
1055529000515	catalytic site [active]
1055529000516	fumarate reductase iron-sulfur subunit; Provisional; Region: frdB; PRK13552
1055529000517	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1055529000518	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1055529000519	fumarate reductase flavoprotein subunit; Provisional; Region: PRK08626
1055529000520	L-aspartate oxidase; Provisional; Region: PRK06175
1055529000521	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1055529000522	fumarate reductase cytochrome b-556 subunit; Provisional; Region: PRK13553
1055529000523	Quinol:fumarate reductase (QFR) Type B subfamily, transmembrane subunit;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinone...; Region: QFR_TypeB_TM; cd00581
1055529000524	Iron-sulfur protein interface; other site
1055529000525	proximal heme binding site [chemical binding]; other site
1055529000526	distal heme binding site [chemical binding]; other site
1055529000527	dimer interface [polypeptide binding]; other site
1055529000528	triosephosphate isomerase; Provisional; Region: PRK14567
1055529000529	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1055529000530	substrate binding site [chemical binding]; other site
1055529000531	dimer interface [polypeptide binding]; other site
1055529000532	catalytic triad [active]
1055529000533	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK08415
1055529000534	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
1055529000535	NAD binding site [chemical binding]; other site
1055529000536	homotetramer interface [polypeptide binding]; other site
1055529000537	homodimer interface [polypeptide binding]; other site
1055529000538	substrate binding site [chemical binding]; other site
1055529000539	active site
1055529000540	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Region: lipid_A_lpxD; TIGR01853
1055529000541	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
1055529000542	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
1055529000543	trimer interface [polypeptide binding]; other site
1055529000544	active site
1055529000545	UDP-GlcNAc binding site [chemical binding]; other site
1055529000546	lipid binding site [chemical binding]; lipid-binding site
1055529000547	S-adenosylmethionine synthetase; Validated; Region: PRK05250
1055529000548	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
1055529000549	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
1055529000550	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
1055529000551	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
1055529000552	active site
1055529000553	multimer interface [polypeptide binding]; other site
1055529000554	Uncharacterized ACR, COG1399; Region: DUF177; cl00616
1055529000555	Ribosomal protein L32 [Translation, ribosomal structure and biogenesis]; Region: RpmF; COG0333
1055529000556	fatty acid/phospholipid synthesis protein PlsX; Region: plsX; TIGR00182
1055529000557	3-oxoacyl-(acyl-carrier-protein) synthase III; Region: fabH; TIGR00747
1055529000558	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1055529000559	dimer interface [polypeptide binding]; other site
1055529000560	active site
1055529000561	CoA binding pocket [chemical binding]; other site
1055529000562	antiporter inner membrane protein; Provisional; Region: PRK11670
1055529000563	Domain of unknown function DUF59; Region: DUF59; pfam01883
1055529000564	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
1055529000565	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
1055529000566	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1055529000567	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
1055529000568	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1055529000569	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
1055529000570	heat shock protein 90; Provisional; Region: PRK05218
1055529000571	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1055529000572	ATP binding site [chemical binding]; other site
1055529000573	Mg2+ binding site [ion binding]; other site
1055529000574	G-X-G motif; other site
1055529000575	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1055529000576	Sel1-like repeats; Region: SEL1; smart00671
1055529000577	Sel1-like repeats; Region: SEL1; smart00671
1055529000578	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1055529000579	TPR motif; other site
1055529000580	binding surface
1055529000581	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
1055529000582	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
1055529000583	metal binding site [ion binding]; metal-binding site
1055529000584	dimer interface [polypeptide binding]; other site
1055529000585	glucose-inhibited division protein A; Region: gidA; TIGR00136
1055529000586	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1055529000587	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
1055529000588	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1055529000589	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1055529000590	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1055529000591	transmembrane helices; other site
1055529000592	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1055529000593	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
1055529000594	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: Dxr; TIGR00243
1055529000595	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
1055529000596	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
1055529000597	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
1055529000598	Beta-1,4-N-acetylgalactosaminyltransferase (CgtA); Region: CgtA; pfam06306
1055529000599	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
1055529000600	substrate binding site [chemical binding]; other site
1055529000601	Helix-turn-helix domain; Region: HTH_28; pfam13518
1055529000602	cysteine desulfurase, NifS family, epsilon proteobacteria type; Region: nifS_epsilon; TIGR03403
1055529000603	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1055529000604	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1055529000605	catalytic residue [active]
1055529000606	Fe-S cluster assembly protein NifU; Region: NifU_proper; TIGR02000
1055529000607	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
1055529000608	trimerization site [polypeptide binding]; other site
1055529000609	active site
1055529000610	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1055529000611	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
1055529000612	DNA repair protein RadA; Region: sms; TIGR00416
1055529000613	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
1055529000614	Walker A motif/ATP binding site; other site
1055529000615	ATP binding site [chemical binding]; other site
1055529000616	Walker B motif; other site
1055529000617	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1055529000618	Peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: MsrA; COG0225
1055529000619	Conserved domain frequently associated with peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: COG0229
1055529000620	SelR domain; Region: SelR; pfam01641
1055529000621	Predicted permeases [General function prediction only]; Region: COG0730
1055529000622	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529000623	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
1055529000624	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
1055529000625	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1055529000626	potential protein location (hypothetical protein HPPN135_01180 [Helicobacter pylori Puno135]) that overlaps RNA (tRNA-N)
1055529000627	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529000628	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
1055529000629	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
1055529000630	Ligand binding site; other site
1055529000631	oligomer interface; other site
1055529000632	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
1055529000633	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1055529000634	hypothetical protein; Provisional; Region: PRK04081
1055529000635	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1055529000636	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1055529000637	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1055529000638	binding surface
1055529000639	TPR motif; other site
1055529000640	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1055529000641	binding surface
1055529000642	TPR motif; other site
1055529000643	Sel1-like repeats; Region: SEL1; smart00671
1055529000644	Sel1-like repeats; Region: SEL1; smart00671
1055529000645	Cytochrome c; Region: Cytochrom_C; cl11414
1055529000646	Porphobilinogen deaminase [Coenzyme metabolism]; Region: HemC; COG0181
1055529000647	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
1055529000648	domain interfaces; other site
1055529000649	active site
1055529000650	prolyl-tRNA synthetase, family II; Region: proS_fam_II; TIGR00409
1055529000651	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
1055529000652	dimer interface [polypeptide binding]; other site
1055529000653	motif 1; other site
1055529000654	active site
1055529000655	motif 2; other site
1055529000656	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
1055529000657	putative deacylase active site [active]
1055529000658	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1055529000659	active site
1055529000660	motif 3; other site
1055529000661	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
1055529000662	anticodon binding site; other site
1055529000663	glutamyl-tRNA reductase; Region: hemA; TIGR01035
1055529000664	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
1055529000665	tRNA; other site
1055529000666	putative tRNA binding site [nucleotide binding]; other site
1055529000667	putative NADP binding site [chemical binding]; other site
1055529000668	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
1055529000669	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1055529000670	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1055529000671	substrate binding pocket [chemical binding]; other site
1055529000672	chain length determination region; other site
1055529000673	substrate-Mg2+ binding site; other site
1055529000674	catalytic residues [active]
1055529000675	aspartate-rich region 1; other site
1055529000676	active site lid residues [active]
1055529000677	aspartate-rich region 2; other site
1055529000678	Domain of unknown function (DUF2018); Region: DUF2018; pfam09442
1055529000679	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
1055529000680	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
1055529000681	dimerization interface [polypeptide binding]; other site
1055529000682	DPS ferroxidase diiron center [ion binding]; other site
1055529000683	ion pore; other site
1055529000684	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1055529000685	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1055529000686	dimer interface [polypeptide binding]; other site
1055529000687	phosphorylation site [posttranslational modification]
1055529000688	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1055529000689	ATP binding site [chemical binding]; other site
1055529000690	Mg2+ binding site [ion binding]; other site
1055529000691	G-X-G motif; other site
1055529000692	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
1055529000693	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
1055529000694	helicase 45; Provisional; Region: PTZ00424
1055529000695	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1055529000696	ATP binding site [chemical binding]; other site
1055529000697	Mg++ binding site [ion binding]; other site
1055529000698	motif III; other site
1055529000699	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1055529000700	nucleotide binding region [chemical binding]; other site
1055529000701	ATP-binding site [chemical binding]; other site
1055529000702	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1055529000703	SPFH domain / Band 7 family; Region: Band_7; pfam01145
1055529000704	Protein of unknown function (DUF2393); Region: DUF2393; pfam09624
1055529000705	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
1055529000706	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1055529000707	Walker A/P-loop; other site
1055529000708	ATP binding site [chemical binding]; other site
1055529000709	Q-loop/lid; other site
1055529000710	ABC transporter signature motif; other site
1055529000711	Walker B; other site
1055529000712	D-loop; other site
1055529000713	H-loop/switch region; other site
1055529000714	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1055529000715	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1055529000716	Walker A/P-loop; other site
1055529000717	ATP binding site [chemical binding]; other site
1055529000718	Q-loop/lid; other site
1055529000719	ABC transporter signature motif; other site
1055529000720	Walker B; other site
1055529000721	D-loop; other site
1055529000722	H-loop/switch region; other site
1055529000723	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1055529000724	potential frameshift: common BLAST hit: gi|188527058|ref|YP_001909745.1| oligopeptide permease integral membrane protein
1055529000725	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529000726	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529000727	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
1055529000728	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
1055529000729	GDP-binding site [chemical binding]; other site
1055529000730	ACT binding site; other site
1055529000731	IMP binding site; other site
1055529000732	Flagellar FliJ protein; Region: FliJ; pfam02050
1055529000733	Uncharacterized conserved protein [Function unknown]; Region: COG3334
1055529000734	RIP metalloprotease RseP; Region: TIGR00054
1055529000735	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1055529000736	active site
1055529000737	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1055529000738	protein binding site [polypeptide binding]; other site
1055529000739	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
1055529000740	putative substrate binding region [chemical binding]; other site
1055529000741	exodeoxyribonuclease VII, large subunit; Region: xseA; TIGR00237
1055529000742	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
1055529000743	generic binding surface II; other site
1055529000744	generic binding surface I; other site
1055529000745	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
1055529000746	DNA methylase; Region: N6_N4_Mtase; pfam01555
1055529000747	DNA methylase; Region: N6_N4_Mtase; pfam01555
1055529000748	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1055529000749	DNA methylase; Region: N6_N4_Mtase; pfam01555
1055529000750	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
1055529000751	Clp amino terminal domain; Region: Clp_N; pfam02861
1055529000752	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1055529000753	Walker A motif; other site
1055529000754	ATP binding site [chemical binding]; other site
1055529000755	Walker B motif; other site
1055529000756	arginine finger; other site
1055529000757	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1055529000758	Walker A motif; other site
1055529000759	ATP binding site [chemical binding]; other site
1055529000760	Walker B motif; other site
1055529000761	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1055529000762	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
1055529000763	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; pfam02683
1055529000764	Dihydroorotase and related cyclic amidohydrolases [Nucleotide transport and metabolism]; Region: PyrC; COG0044
1055529000765	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1055529000766	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1055529000767	active site
1055529000768	chlorohydrolase; Provisional; Region: PRK08418
1055529000769	Metallo-dependent hydrolases, subgroup D is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_D; cd01312
1055529000770	active site
1055529000771	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1055529000772	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14339
1055529000773	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1055529000774	FeS/SAM binding site; other site
1055529000775	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: DUF374; Region: LPLAT_DUF374-like; cd07983
1055529000776	putative acyl-acceptor binding pocket; other site
1055529000777	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
1055529000778	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1055529000779	Exopolyphosphatase [Nucleotide transport and metabolism / Inorganic ion transport and metabolism]; Region: GppA; COG0248
1055529000780	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1055529000781	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1055529000782	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1055529000783	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1055529000784	putative active site [active]
1055529000785	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1055529000786	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1055529000787	putative acyl-acceptor binding pocket; other site
1055529000788	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1055529000789	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
1055529000790	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3400
1055529000791	TrkA-C domain; Region: TrkA_C; pfam02080
1055529000792	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
1055529000793	active site
1055529000794	dimer interface [polypeptide binding]; other site
1055529000795	metal binding site [ion binding]; metal-binding site
1055529000796	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1055529000797	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1055529000798	radical SAM methylthiotransferase, MiaB/RimO family; Region: TIGR00089
1055529000799	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1055529000800	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1055529000801	FeS/SAM binding site; other site
1055529000802	ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones]; Region: HflB; COG0465
1055529000803	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1055529000804	Walker A motif; other site
1055529000805	ATP binding site [chemical binding]; other site
1055529000806	Walker B motif; other site
1055529000807	arginine finger; other site
1055529000808	Domain of unknown function (DUF4149); Region: DUF4149; pfam13664
1055529000809	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
1055529000810	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
1055529000811	PPE-repeat proteins [Cell motility and secretion]; Region: COG5651
1055529000812	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
1055529000813	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1055529000814	diaminopimelate decarboxylase; Region: lysA; TIGR01048
1055529000815	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
1055529000816	active site
1055529000817	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1055529000818	substrate binding site [chemical binding]; other site
1055529000819	catalytic residues [active]
1055529000820	dimer interface [polypeptide binding]; other site
1055529000821	Chorismate mutase [Amino acid transport and metabolism]; Region: PheA; COG1605
1055529000822	Uncharacterized conserved protein [Function unknown]; Region: COG4866
1055529000823	aminodeoxychorismate synthase; Provisional; Region: PRK07508
1055529000824	chorismate binding enzyme; Region: Chorismate_bind; cl10555
1055529000825	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cl00224
1055529000826	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1055529000827	substrate-cofactor binding pocket; other site
1055529000828	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1055529000829	catalytic residue [active]
1055529000830	acylamide amidohydrolase; Provisional; Region: amiE; PRK13286
1055529000831	aliphatic amidases (class 2 nitrilases); Region: aliphatic_amidase; cd07565
1055529000832	multimer interface [polypeptide binding]; other site
1055529000833	active site
1055529000834	catalytic triad [active]
1055529000835	dimer interface [polypeptide binding]; other site
1055529000836	flagellar hook-associated protein FlgL; Validated; Region: flgL; PRK08412
1055529000837	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1055529000838	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
1055529000839	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1055529000840	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1055529000841	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1055529000842	peptide binding site [polypeptide binding]; other site
1055529000843	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1055529000844	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1055529000845	dimer interface [polypeptide binding]; other site
1055529000846	conserved gate region; other site
1055529000847	putative PBP binding loops; other site
1055529000848	ABC-ATPase subunit interface; other site
1055529000849	dipeptide transporter; Provisional; Region: PRK10913
1055529000850	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1055529000851	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1055529000852	dimer interface [polypeptide binding]; other site
1055529000853	conserved gate region; other site
1055529000854	putative PBP binding loops; other site
1055529000855	ABC-ATPase subunit interface; other site
1055529000856	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1055529000857	nickel import ATP-binding protein NikD; Region: nickel_nikD; TIGR02770
1055529000858	Walker A/P-loop; other site
1055529000859	ATP binding site [chemical binding]; other site
1055529000860	Q-loop/lid; other site
1055529000861	ABC transporter signature motif; other site
1055529000862	Walker B; other site
1055529000863	D-loop; other site
1055529000864	H-loop/switch region; other site
1055529000865	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1055529000866	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1055529000867	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1055529000868	Walker A/P-loop; other site
1055529000869	ATP binding site [chemical binding]; other site
1055529000870	Q-loop/lid; other site
1055529000871	ABC transporter signature motif; other site
1055529000872	Walker B; other site
1055529000873	D-loop; other site
1055529000874	H-loop/switch region; other site
1055529000875	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1055529000876	GTPase CgtA; Reviewed; Region: obgE; PRK12299
1055529000877	GTP1/OBG; Region: GTP1_OBG; pfam01018
1055529000878	Obg GTPase; Region: Obg; cd01898
1055529000879	G1 box; other site
1055529000880	GTP/Mg2+ binding site [chemical binding]; other site
1055529000881	Switch I region; other site
1055529000882	G2 box; other site
1055529000883	G3 box; other site
1055529000884	Switch II region; other site
1055529000885	G4 box; other site
1055529000886	G5 box; other site
1055529000887	Alginate lyase; Region: Alginate_lyase; pfam05426
1055529000888	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
1055529000889	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1055529000890	inhibitor-cofactor binding pocket; inhibition site
1055529000891	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1055529000892	catalytic residue [active]
1055529000893	Putative F0F1-ATPase subunit (ATPase_gene1); Region: ATPase_gene1; pfam09527
1055529000894	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1055529000895	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cd07197
1055529000896	active site
1055529000897	catalytic triad [active]
1055529000898	dimer interface [polypeptide binding]; other site
1055529000899	Catalytic domain of Helicobacter pylori peptidoglycan deacetylase (HpPgdA) and similar proteins; Region: CE4_HpPgdA_like; cd10938
1055529000900	active site
1055529000901	catalytic site [active]
1055529000902	Zn binding site [ion binding]; other site
1055529000903	tetramer interface [polypeptide binding]; other site
1055529000904	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1055529000905	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1055529000906	DNA methylase; Region: N6_N4_Mtase; pfam01555
1055529000907	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
1055529000908	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
1055529000909	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
1055529000910	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1055529000911	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1055529000912	putative substrate translocation pore; other site
1055529000913	heme oxygenase, HugZ family; Region: heme_ox_HugZ; TIGR04109
1055529000914	Protein of unknown function (DUF2470); Region: DUF2470; pfam10615
1055529000915	Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381
1055529000916	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
1055529000917	arginyl-tRNA synthetase; Region: argS; TIGR00456
1055529000918	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
1055529000919	active site
1055529000920	HIGH motif; other site
1055529000921	KMSK motif region; other site
1055529000922	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1055529000923	tRNA binding surface [nucleotide binding]; other site
1055529000924	anticodon binding site; other site
1055529000925	mttA/Hcf106 family; Region: MttA_Hcf106; cl00788
1055529000926	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
1055529000927	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1055529000928	catalytic site [active]
1055529000929	G-X2-G-X-G-K; other site
1055529000930	nuclease NucT; Provisional; Region: PRK13912
1055529000931	Catalytic domain of EDTA-resistant nuclease Nuc, vertebrate phospholipase D6, and similar proteins; Region: PLDc_Nuc_like; cd09116
1055529000932	putative active site [active]
1055529000933	catalytic site [active]
1055529000934	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529000935	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
1055529000936	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
1055529000937	CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513
1055529000938	ligand binding site; other site
1055529000939	tetramer interface; other site
1055529000940	Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: spsG; COG3980
1055529000941	pseudaminic acid biosynthesis N-acetyl transferase; Region: PseH; TIGR03585
1055529000942	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1055529000943	Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663
1055529000944	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
1055529000945	NAD synthetase; Provisional; Region: PRK13980
1055529000946	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
1055529000947	homodimer interface [polypeptide binding]; other site
1055529000948	NAD binding pocket [chemical binding]; other site
1055529000949	ATP binding pocket [chemical binding]; other site
1055529000950	Mg binding site [ion binding]; other site
1055529000951	active-site loop [active]
1055529000952	ketol-acid reductoisomerase; Provisional; Region: PRK05479
1055529000953	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
1055529000954	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1055529000955	Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning]; Region: MinD; COG2894
1055529000956	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
1055529000957	Switch I; other site
1055529000958	Switch II; other site
1055529000959	cell division topological specificity factor MinE; Region: minE; TIGR01215
1055529000960	DNA protecting protein DprA; Region: dprA; TIGR00732
1055529000961	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758
1055529000962	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
1055529000963	Sel1-like repeats; Region: SEL1; smart00671
1055529000964	Sel1-like repeats; Region: SEL1; smart00671
1055529000965	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1055529000966	Sel1-like repeats; Region: SEL1; smart00671
1055529000967	Sel1-like repeats; Region: SEL1; smart00671
1055529000968	Sel1-like repeats; Region: SEL1; smart00671
1055529000969	Sel1-like repeats; Region: SEL1; smart00671
1055529000970	Sel1-like repeats; Region: SEL1; smart00671
1055529000971	Sel1-like repeats; Region: SEL1; smart00671
1055529000972	chlorohydrolase; Provisional; Region: PRK07213
1055529000973	Predicted membrane protein [Function unknown]; Region: COG3326
1055529000974	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1055529000975	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1055529000976	active site
1055529000977	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
1055529000978	DHH family; Region: DHH; pfam01368
1055529000979	DHHA1 domain; Region: DHHA1; pfam02272
1055529000980	CTP synthetase; Validated; Region: pyrG; PRK05380
1055529000981	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
1055529000982	Catalytic site [active]
1055529000983	active site
1055529000984	UTP binding site [chemical binding]; other site
1055529000985	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
1055529000986	active site
1055529000987	putative oxyanion hole; other site
1055529000988	catalytic triad [active]
1055529000989	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474
1055529000990	flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF); Region: fliF; TIGR00206
1055529000991	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
1055529000992	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
1055529000993	flagellar motor switch protein FliG; Region: fliG; TIGR00207
1055529000994	FliG C-terminal domain; Region: FliG_C; pfam01706
1055529000995	flagellar assembly protein H; Validated; Region: fliH; PRK06669
1055529000996	Flagellar assembly protein FliH; Region: FliH; pfam02108
1055529000997	1-deoxy-D-xylulose-5-phosphate synthase; Region: dxs; TIGR00204
1055529000998	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
1055529000999	TPP-binding site; other site
1055529001000	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1055529001001	PYR/PP interface [polypeptide binding]; other site
1055529001002	dimer interface [polypeptide binding]; other site
1055529001003	TPP binding site [chemical binding]; other site
1055529001004	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1055529001005	GTP-binding protein LepA; Provisional; Region: PRK05433
1055529001006	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1055529001007	G1 box; other site
1055529001008	putative GEF interaction site [polypeptide binding]; other site
1055529001009	GTP/Mg2+ binding site [chemical binding]; other site
1055529001010	Switch I region; other site
1055529001011	G2 box; other site
1055529001012	G3 box; other site
1055529001013	Switch II region; other site
1055529001014	G4 box; other site
1055529001015	G5 box; other site
1055529001016	Translation_Factor_II_like: Elongation factor Tu (EF-Tu) domain II-like proteins. Elongation factor Tu consists of three structural domains, this family represents the second domain. Domain II adopts a beta barrel structure and is involved in binding to...; Region: Translation_Factor_II_like; cl02787
1055529001017	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1055529001018	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1055529001019	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1055529001020	DNA-methyltransferase (dcm); Region: dcm; TIGR00675
1055529001021	cofactor binding site; other site
1055529001022	DNA binding site [nucleotide binding]
1055529001023	substrate interaction site [chemical binding]; other site
1055529001024	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgG; COG4786
1055529001025	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
1055529001026	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
1055529001027	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1055529001028	putative substrate translocation pore; other site
1055529001029	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
1055529001030	TspO/MBR family; Region: TspO_MBR; cl01379
1055529001031	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1055529001032	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
1055529001033	Inactivated superfamily I helicase [DNA replication, recombination, and repair]; Region: COG3893
1055529001034	RecB family exonuclease [DNA replication, recombination, and repair]; Region: COG2887
1055529001035	transketolase, bacterial and yeast; Region: tktlase_bact; TIGR00232
1055529001036	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1055529001037	TPP-binding site [chemical binding]; other site
1055529001038	dimer interface [polypeptide binding]; other site
1055529001039	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1055529001040	PYR/PP interface [polypeptide binding]; other site
1055529001041	dimer interface [polypeptide binding]; other site
1055529001042	TPP binding site [chemical binding]; other site
1055529001043	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1055529001044	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
1055529001045	riboflavin kinase/FMN adenylyltransferase; Region: ribF; TIGR00083
1055529001046	active site
1055529001047	Riboflavin kinase; Region: Flavokinase; smart00904
1055529001048	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1055529001049	hemolysin TlyA family protein; Region: tly; TIGR00478
1055529001050	RNA binding surface [nucleotide binding]; other site
1055529001051	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1055529001052	S-adenosylmethionine binding site [chemical binding]; other site
1055529001053	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
1055529001054	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1055529001055	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1055529001056	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
1055529001057	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1055529001058	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1055529001059	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1055529001060	Walker A/P-loop; other site
1055529001061	ATP binding site [chemical binding]; other site
1055529001062	Q-loop/lid; other site
1055529001063	ABC transporter signature motif; other site
1055529001064	Walker B; other site
1055529001065	D-loop; other site
1055529001066	H-loop/switch region; other site
1055529001067	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
1055529001068	Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes [Defense mechanisms]; Region: COG1787
1055529001069	Restriction endonuclease; Region: Mrr_cat; pfam04471
1055529001070	Predicted ATPases [General function prediction only]; Region: COG1106
1055529001071	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1055529001072	Walker A/P-loop; other site
1055529001073	ATP binding site [chemical binding]; other site
1055529001074	High-affinity nickel permease [Inorganic ion transport and metabolism]; Region: HoxN; COG3376
1055529001075	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cd00596
1055529001076	active site
1055529001077	Zn binding site [ion binding]; other site
1055529001078	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1055529001079	metal-binding site [ion binding]
1055529001080	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1055529001081	metal-binding site [ion binding]
1055529001082	copper-(or silver)-translocating P-type ATPase; Region: ATPase-IB1_Cu; TIGR01511
1055529001083	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1055529001084	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1055529001085	Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183
1055529001086	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
1055529001087	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
1055529001088	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1055529001089	Walker A motif; other site
1055529001090	ATP binding site [chemical binding]; other site
1055529001091	Walker B motif; other site
1055529001092	arginine finger; other site
1055529001093	Peptidase family M41; Region: Peptidase_M41; pfam01434
1055529001094	ribosomal protein L11 methyltransferase; Region: prmA; TIGR00406
1055529001095	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1055529001096	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1055529001097	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1055529001098	active site
1055529001099	phosphorylation site [posttranslational modification]
1055529001100	intermolecular recognition site; other site
1055529001101	dimerization interface [polypeptide binding]; other site
1055529001102	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529001103	rRNA small subunit methyltransferase G; Region: GidB; pfam02527
1055529001104	16S rRNA (guanine(527)-N(7))-methyltransferase GidB; Region: gidB; TIGR00138
1055529001105	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
1055529001106	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1055529001107	Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion]; Region: TatC; COG0805
1055529001108	sec-independent translocase; Provisional; Region: PRK04098
1055529001109	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
1055529001110	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1055529001111	Walker A motif; other site
1055529001112	ATP binding site [chemical binding]; other site
1055529001113	Walker B motif; other site
1055529001114	arginine finger; other site
1055529001115	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1055529001116	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
1055529001117	oligomerization interface [polypeptide binding]; other site
1055529001118	active site
1055529001119	metal binding site [ion binding]; metal-binding site
1055529001120	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529001121	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529001122	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1055529001123	septum formation inhibitor; Reviewed; Region: minC; PRK00556
1055529001124	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
1055529001125	UDP-3-0-acyl N-acetylglucosamine deacetylase; Region: lpxC; TIGR00325
1055529001126	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
1055529001127	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
1055529001128	homoserine kinase; Region: thrB; TIGR00191
1055529001129	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1055529001130	Predicted nucleic-acid-binding protein implicated in transcription termination [Transcription]; Region: COG2740
1055529001131	putative RNA binding cleft [nucleotide binding]; other site
1055529001132	translation initiation factor IF-2; Region: IF-2; TIGR00487
1055529001133	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1055529001134	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1055529001135	G1 box; other site
1055529001136	putative GEF interaction site [polypeptide binding]; other site
1055529001137	GTP/Mg2+ binding site [chemical binding]; other site
1055529001138	Switch I region; other site
1055529001139	G2 box; other site
1055529001140	G3 box; other site
1055529001141	Switch II region; other site
1055529001142	G4 box; other site
1055529001143	G5 box; other site
1055529001144	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1055529001145	Translation-initiation factor 2; Region: IF-2; pfam11987
1055529001146	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1055529001147	Ribosome-binding factor A; Region: RBFA; cl00542
1055529001148	Uncharacterized BCR, YhbC family COG0779; Region: DUF150; pfam02576
1055529001149	Sm and related proteins; Region: Sm_like; cl00259
1055529001150	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
1055529001151	putative oligomer interface [polypeptide binding]; other site
1055529001152	putative RNA binding site [nucleotide binding]; other site
1055529001153	acetyl-CoA synthetase; Provisional; Region: PRK00174
1055529001154	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
1055529001155	active site
1055529001156	CoA binding site [chemical binding]; other site
1055529001157	acyl-activating enzyme (AAE) consensus motif; other site
1055529001158	AMP binding site [chemical binding]; other site
1055529001159	acetate binding site [chemical binding]; other site
1055529001160	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
1055529001161	putative active site [active]
1055529001162	putative metal binding site [ion binding]; other site
1055529001163	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1055529001164	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1055529001165	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1055529001166	active site
1055529001167	intermolecular recognition site; other site
1055529001168	dimerization interface [polypeptide binding]; other site
1055529001169	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1055529001170	DNA binding site [nucleotide binding]
1055529001171	Predicted phosphohydrolase (DHH superfamily) [General function prediction only]; Region: COG2404
1055529001172	DHH family; Region: DHH; pfam01368
1055529001173	flagellar biosynthesis protein FlhA; Region: FlhA; TIGR01398
1055529001174	FHIPEP family; Region: FHIPEP; pfam00771
1055529001175	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1055529001176	16S/18S rRNA binding site [nucleotide binding]; other site
1055529001177	S13e-L30e interaction site [polypeptide binding]; other site
1055529001178	25S rRNA binding site [nucleotide binding]; other site
1055529001179	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
1055529001180	O-Antigen ligase; Region: Wzy_C; pfam04932
1055529001181	Dehydroquinase class II; Region: DHquinase_II; pfam01220
1055529001182	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
1055529001183	trimer interface [polypeptide binding]; other site
1055529001184	active site
1055529001185	dimer interface [polypeptide binding]; other site
1055529001186	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
1055529001187	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1055529001188	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
1055529001189	active site
1055529001190	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
1055529001191	catalytic center binding site [active]
1055529001192	ATP binding site [chemical binding]; other site
1055529001193	flagellar biosynthesis regulator FlhF; Validated; Region: flhF; PRK05703
1055529001194	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1055529001195	Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]; Region: flhG; COG0455
1055529001196	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1055529001197	FleN is a member of the Fer4_NifH superfamily. It shares the common function as an ATPase, with the ATP-binding domain at the N-terminus. In Pseudomonas aeruginosa, FleN gene is involved in regulating the number of flagella and chemotactic motility by...; Region: FleN-like; cd02038
1055529001198	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
1055529001199	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1055529001200	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1055529001201	DNA binding residues [nucleotide binding]
1055529001202	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
1055529001203	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
1055529001204	flagellar motor switch protein FliY; Validated; Region: PRK08432
1055529001205	flagellar motor switch protein FliN; Region: fliN; TIGR02480
1055529001206	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1055529001207	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4731
1055529001208	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1055529001209	metal binding site 2 [ion binding]; metal-binding site
1055529001210	putative DNA binding helix; other site
1055529001211	metal binding site 1 [ion binding]; metal-binding site
1055529001212	dimer interface [polypeptide binding]; other site
1055529001213	structural Zn2+ binding site [ion binding]; other site
1055529001214	ATPase related to the helicase subunit of the Holliday junction resolvase [DNA replication, recombination, and repair]; Region: MGS1; COG2256
1055529001215	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1055529001216	Walker A motif; other site
1055529001217	ATP binding site [chemical binding]; other site
1055529001218	Walker B motif; other site
1055529001219	arginine finger; other site
1055529001220	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
1055529001221	Helix-Turn-Helix DNA binding domain of the HspR transcription regulator; Region: HTH_HspR; cd04766
1055529001222	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1055529001223	DNA binding residues [nucleotide binding]
1055529001224	putative dimer interface [polypeptide binding]; other site
1055529001225	chaperone protein DnaJ; Provisional; Region: PRK14299
1055529001226	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1055529001227	HSP70 interaction site [polypeptide binding]; other site
1055529001228	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1055529001229	substrate binding site [polypeptide binding]; other site
1055529001230	dimer interface [polypeptide binding]; other site
1055529001231	5'-3' exonuclease; Provisional; Region: PRK14976
1055529001232	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
1055529001233	putative active site [active]
1055529001234	Helix-hairpin-helix class 2 (Pol1 family) motifs; Region: HhH2; smart00279
1055529001235	DNA binding site [nucleotide binding]
1055529001236	metal binding site [ion binding]; metal-binding site
1055529001237	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1055529001238	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1055529001239	active site
1055529001240	dimerization interface [polypeptide binding]; other site
1055529001241	bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein; Provisional; Region: ispDF; PRK09382
1055529001242	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
1055529001243	substrate binding site; other site
1055529001244	dimer interface; other site
1055529001245	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
1055529001246	homotrimer interaction site [polypeptide binding]; other site
1055529001247	zinc binding site [ion binding]; other site
1055529001248	CDP-binding sites; other site
1055529001249	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
1055529001250	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1055529001251	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1055529001252	protein binding site [polypeptide binding]; other site
1055529001253	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1055529001254	protein binding site [polypeptide binding]; other site
1055529001255	S-methylmethionine transporter; Provisional; Region: PRK11387
1055529001256	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Region: pgsA; TIGR00560
1055529001257	7-alpha-hydroxysteroid dehydrogenase; Provisional; Region: PRK08416
1055529001258	1-cyclohexenylcarbonyl_coenzyme A_reductase (ChcA)_like, classical (c) SDRs; Region: ChcA_like_SDR_c; cd05359
1055529001259	putative NAD(P) binding site [chemical binding]; other site
1055529001260	active site
1055529001261	dihydrodipicolinate synthase; Region: dapA; TIGR00674
1055529001262	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1055529001263	dimer interface [polypeptide binding]; other site
1055529001264	active site
1055529001265	catalytic residue [active]
1055529001266	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1055529001267	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1055529001268	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1055529001269	dihydroorotate dehydrogenase, subfamily 2; Region: pyrD_sub2; TIGR01036
1055529001270	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
1055529001271	quinone interaction residues [chemical binding]; other site
1055529001272	active site
1055529001273	catalytic residues [active]
1055529001274	FMN binding site [chemical binding]; other site
1055529001275	substrate binding site [chemical binding]; other site
1055529001276	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
1055529001277	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
1055529001278	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
1055529001279	Catalytic C-terminal domain, first repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C1_like; cd09165
1055529001280	putative domain interface [polypeptide binding]; other site
1055529001281	putative active site [active]
1055529001282	catalytic site [active]
1055529001283	Catalytic C-terminal domain, second repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C2_like; cd09168
1055529001284	putative active site [active]
1055529001285	putative domain interface [polypeptide binding]; other site
1055529001286	catalytic site [active]
1055529001287	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1055529001288	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1055529001289	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
1055529001290	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1055529001291	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
1055529001292	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
1055529001293	ATP binding site [chemical binding]; other site
1055529001294	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
1055529001295	putative Mg++ binding site [ion binding]; other site
1055529001296	methionine gamma-lyase; Region: PLN02242
1055529001297	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
1055529001298	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
1055529001299	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2604
1055529001300	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
1055529001301	putative metal binding site [ion binding]; other site
1055529001302	CoB--CoM heterodisulfide reductase, subunit B; Region: CoB_CoM_SS_B; TIGR03288
1055529001303	oligoendopeptidase, pepF/M3 family; Region: M3_fam_3; TIGR02290
1055529001304	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_5; cd09610
1055529001305	active site
1055529001306	Zn binding site [ion binding]; other site
1055529001307	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
1055529001308	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
1055529001309	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529001310	ABC-type molybdate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: ModA; COG0725
1055529001311	molybdenum ABC transporter, periplasmic molybdate-binding protein; Region: modA; TIGR01256
1055529001312	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1055529001313	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1055529001314	dimer interface [polypeptide binding]; other site
1055529001315	conserved gate region; other site
1055529001316	putative PBP binding loops; other site
1055529001317	ABC-ATPase subunit interface; other site
1055529001318	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1055529001319	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1055529001320	Walker A/P-loop; other site
1055529001321	ATP binding site [chemical binding]; other site
1055529001322	Q-loop/lid; other site
1055529001323	ABC transporter signature motif; other site
1055529001324	Walker B; other site
1055529001325	D-loop; other site
1055529001326	H-loop/switch region; other site
1055529001327	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
1055529001328	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
1055529001329	active site
1055529001330	HIGH motif; other site
1055529001331	nucleotide binding site [chemical binding]; other site
1055529001332	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1055529001333	active site
1055529001334	KMSKS motif; other site
1055529001335	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529001336	Helix-turn-helix domain; Region: HTH_17; pfam12728
1055529001337	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827
1055529001338	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1055529001339	TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950
1055529001340	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1055529001341	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1055529001342	ADP-heptose:LPS heptosyl transferase I; Provisional; Region: PRK10964; cl15782
1055529001343	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
1055529001344	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
1055529001345	G1 box; other site
1055529001346	putative GEF interaction site [polypeptide binding]; other site
1055529001347	GTP/Mg2+ binding site [chemical binding]; other site
1055529001348	Switch I region; other site
1055529001349	G2 box; other site
1055529001350	G3 box; other site
1055529001351	Switch II region; other site
1055529001352	G4 box; other site
1055529001353	G5 box; other site
1055529001354	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
1055529001355	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
1055529001356	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dam; COG0338
1055529001357	Catalytic GIY-YIG domain of coliphage T4 non-specific endonuclease II, type II restriction endonuclease R.Hpy188I, and similar proteins; Region: GIY-YIG_EndoII_Hpy188I_like; cd10436
1055529001358	GIY-YIG motif/motif A; other site
1055529001359	DNA binding site [nucleotide binding]
1055529001360	active site
1055529001361	catalytic site [active]
1055529001362	metal binding site [ion binding]; metal-binding site
1055529001363	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
1055529001364	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1055529001365	cofactor binding site; other site
1055529001366	DNA binding site [nucleotide binding]
1055529001367	substrate interaction site [chemical binding]; other site
1055529001368	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
1055529001369	Catalase-like heme-binding proteins similar to the uncharacterized srpA; Region: srpA_like; cd08153
1055529001370	putative heme binding pocket [chemical binding]; other site
1055529001371	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
1055529001372	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
1055529001373	Protein of unknown function (DUF3519); Region: DUF3519; pfam12033
1055529001374	Cation transport protein; Region: TrkH; cl17365
1055529001375	Kef-type K+ transport systems, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: Kch; COG1226
1055529001376	TrkA-N domain; Region: TrkA_N; pfam02254
1055529001377	TrkA-C domain; Region: TrkA_C; pfam02080
1055529001378	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
1055529001379	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
1055529001380	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
1055529001381	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1055529001382	Mg++ binding site [ion binding]; other site
1055529001383	putative catalytic motif [active]
1055529001384	putative substrate binding site [chemical binding]; other site
1055529001385	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03815
1055529001386	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1055529001387	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1055529001388	Protein of unknown function (DUF493); Region: DUF493; pfam04359
1055529001389	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1055529001390	active site
1055529001391	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
1055529001392	Na2 binding site [ion binding]; other site
1055529001393	putative substrate binding site 1 [chemical binding]; other site
1055529001394	Na binding site 1 [ion binding]; other site
1055529001395	putative substrate binding site 2 [chemical binding]; other site
1055529001396	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
1055529001397	Na2 binding site [ion binding]; other site
1055529001398	putative substrate binding site 1 [chemical binding]; other site
1055529001399	Na binding site 1 [ion binding]; other site
1055529001400	putative substrate binding site 2 [chemical binding]; other site
1055529001401	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
1055529001402	dimerization interface [polypeptide binding]; other site
1055529001403	substrate binding site [chemical binding]; other site
1055529001404	active site
1055529001405	calcium binding site [ion binding]; other site
1055529001406	DNA polymerase III, beta subunit; Region: dnan; TIGR00663
1055529001407	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1055529001408	putative DNA binding surface [nucleotide binding]; other site
1055529001409	dimer interface [polypeptide binding]; other site
1055529001410	beta-clamp/clamp loader binding surface; other site
1055529001411	beta-clamp/translesion DNA polymerase binding surface; other site
1055529001412	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
1055529001413	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1055529001414	Mg2+ binding site [ion binding]; other site
1055529001415	G-X-G motif; other site
1055529001416	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1055529001417	anchoring element; other site
1055529001418	dimer interface [polypeptide binding]; other site
1055529001419	ATP binding site [chemical binding]; other site
1055529001420	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1055529001421	active site
1055529001422	putative metal-binding site [ion binding]; other site
1055529001423	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1055529001424	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1055529001425	Peptidase family M23; Region: Peptidase_M23; pfam01551
1055529001426	nudix-type nucleoside diphosphatase, YffH/AdpP family; Region: TIGR00052
1055529001427	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1055529001428	dimer interface [polypeptide binding]; other site
1055529001429	ADP-ribose binding site [chemical binding]; other site
1055529001430	active site
1055529001431	nudix motif; other site
1055529001432	metal binding site [ion binding]; metal-binding site
1055529001433	FAD binding domain; Region: FAD_binding_4; pfam01565
1055529001434	glycolate oxidase, subunit GlcD; Region: glcD; TIGR00387
1055529001435	Protein-interacting Bro1-like domain of mammalian Alix and related domains; Region: BRO1_Alix_like; cl14649
1055529001436	dihydrodipicolinate reductase; Region: dapB; TIGR00036
1055529001437	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1055529001438	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1055529001439	glutamine synthetase, type I; Region: GlnA; TIGR00653
1055529001440	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
1055529001441	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1055529001442	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
1055529001443	Uncharacterized conserved protein [Function unknown]; Region: COG1479
1055529001444	Protein of unknown function DUF262; Region: DUF262; pfam03235
1055529001445	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
1055529001446	Uncharacterized conserved protein [Function unknown]; Region: COG3586
1055529001447	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1055529001448	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1055529001449	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1055529001450	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
1055529001451	active site
1055529001452	HslU subunit interaction site [polypeptide binding]; other site
1055529001453	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
1055529001454	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1055529001455	Walker A motif; other site
1055529001456	ATP binding site [chemical binding]; other site
1055529001457	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1055529001458	Walker B motif; other site
1055529001459	arginine finger; other site
1055529001460	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1055529001461	GTPase [General function prediction only]; Region: Era; COG1159
1055529001462	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
1055529001463	G1 box; other site
1055529001464	GTP/Mg2+ binding site [chemical binding]; other site
1055529001465	Switch I region; other site
1055529001466	G2 box; other site
1055529001467	Switch II region; other site
1055529001468	G3 box; other site
1055529001469	G4 box; other site
1055529001470	G5 box; other site
1055529001471	KH domain; Region: KH_2; pfam07650
1055529001472	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
1055529001473	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1055529001474	Sel1-like repeats; Region: SEL1; smart00671
1055529001475	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
1055529001476	Type IV secretory pathway, VirD4 components [Intracellular trafficking and secretion]; Region: VirD4; COG3505
1055529001477	The TraG/TraD/VirD4 family are bacterial conjugation proteins involved in type IV secretion. These proteins aid the transfer of DNA from the plasmid into the host bacterial chromosome. They contain an ATP binding domain. VirD4 is involved in DNA transfer...; Region: TraG_VirD4; cd01126
1055529001478	Walker A motif; other site
1055529001479	ATP binding site [chemical binding]; other site
1055529001480	Walker B motif; other site
1055529001481	P-type DNA transfer ATPase VirB11; Region: VirB11; TIGR02788
1055529001482	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
1055529001483	ATP binding site [chemical binding]; other site
1055529001484	Walker A motif; other site
1055529001485	hexamer interface [polypeptide binding]; other site
1055529001486	Walker B motif; other site
1055529001487	CagZ; Region: CagZ; pfam09053
1055529001488	DC-EC Repeat; Region: CagY_M; pfam07337
1055529001489	DC-EC Repeat; Region: CagY_M; pfam07337
1055529001490	DC-EC Repeat; Region: CagY_M; pfam07337
1055529001491	DC-EC Repeat; Region: CagY_M; pfam07337
1055529001492	DC-EC Repeat; Region: CagY_M; pfam07337
1055529001493	DC-EC Repeat; Region: CagY_M; pfam07337
1055529001494	DC-EC Repeat; Region: CagY_M; pfam07337
1055529001495	DC-EC Repeat; Region: CagY_M; pfam07337
1055529001496	Type IV secretory pathway, VirB10 components [Intracellular trafficking and secretion]; Region: VirB10; COG2948
1055529001497	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cl11423
1055529001498	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911
1055529001499	VirB7 interaction site; other site
1055529001500	Type IV secretory pathway, component VirB8 [Intracellular trafficking and secretion]; Region: VirB8; COG3736
1055529001501	Cag pathogenicity island protein Cag12; Region: Cag12; pfam13117
1055529001502	prolyl-tRNA synthetase; Provisional; Region: PRK08661
1055529001503	type IV secretion/conjugal transfer ATPase, VirB4 family; Region: VirB4_CagE; TIGR00929
1055529001504	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
1055529001505	CagA exotoxin; Region: CagA; pfam03507
1055529001506	CagA exotoxin; Region: CagA; pfam03507
1055529001507	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
1055529001508	transcription termination factor Rho; Provisional; Region: rho; PRK09376
1055529001509	Rho termination factor, N-terminal domain; Region: Rho_N; pfam07498
1055529001510	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
1055529001511	RNA binding site [nucleotide binding]; other site
1055529001512	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
1055529001513	multimer interface [polypeptide binding]; other site
1055529001514	Walker A motif; other site
1055529001515	ATP binding site [chemical binding]; other site
1055529001516	Walker B motif; other site
1055529001517	Ribosomal protein L31; Region: Ribosomal_L31; pfam01197
1055529001518	Predicted methyltransferases [General function prediction only]; Region: COG0313
1055529001519	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1055529001520	putative SAM binding site [chemical binding]; other site
1055529001521	putative homodimer interface [polypeptide binding]; other site
1055529001522	rRNA methylase, putative, group 3; Region: rRNA_methyl_3; TIGR00186
1055529001523	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
1055529001524	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1055529001525	acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Region: accA; TIGR00513
1055529001526	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
1055529001527	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK08439
1055529001528	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1055529001529	dimer interface [polypeptide binding]; other site
1055529001530	active site
1055529001531	acyl carrier protein; Provisional; Region: acpP; PRK00982
1055529001532	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1055529001533	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1055529001534	NAD(P) binding site [chemical binding]; other site
1055529001535	active site
1055529001536	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
1055529001537	Phosphatidylinositol-specific phospholipase C, Y domain; Region: PI-PLC-Y; cl14781
1055529001538	Predicted membrane protein [Function unknown]; Region: COG3059
1055529001539	diaminopimelate epimerase; Region: DapF; TIGR00652
1055529001540	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1055529001541	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1055529001542	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1055529001543	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1055529001544	Domain of unknown function (DUF4008); Region: DUF4008; pfam13186
1055529001545	GTP-binding protein YchF; Reviewed; Region: PRK09601
1055529001546	YchF GTPase; Region: YchF; cd01900
1055529001547	G1 box; other site
1055529001548	GTP/Mg2+ binding site [chemical binding]; other site
1055529001549	Switch I region; other site
1055529001550	G2 box; other site
1055529001551	Switch II region; other site
1055529001552	G3 box; other site
1055529001553	G4 box; other site
1055529001554	G5 box; other site
1055529001555	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1055529001556	multifunctional aminopeptidase A; Provisional; Region: PRK00913
1055529001557	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1055529001558	interface (dimer of trimers) [polypeptide binding]; other site
1055529001559	Substrate-binding/catalytic site; other site
1055529001560	Zn-binding sites [ion binding]; other site
1055529001561	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1055529001562	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1055529001563	active site
1055529001564	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
1055529001565	Ribose/Galactose Isomerase; Region: LacAB_rpiB; cl00485
1055529001566	Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_1; cd06158
1055529001567	Peptidase family M50; Region: Peptidase_M50; pfam02163
1055529001568	active site
1055529001569	putative substrate binding region [chemical binding]; other site
1055529001570	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
1055529001571	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1055529001572	Catalytic site [active]
1055529001573	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1055529001574	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14191
1055529001575	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1055529001576	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1055529001577	homodimer interface [polypeptide binding]; other site
1055529001578	NADP binding site [chemical binding]; other site
1055529001579	substrate binding site [chemical binding]; other site
1055529001580	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
1055529001581	Sulfatase; Region: Sulfatase; pfam00884
1055529001582	Predicted neuraminidase (sialidase) [Carbohydrate transport and metabolism]; Region: COG4692
1055529001583	BNR repeat-like domain; Region: BNR_2; pfam13088
1055529001584	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
1055529001585	active site
1055529001586	substrate binding pocket [chemical binding]; other site
1055529001587	dimer interface [polypeptide binding]; other site
1055529001588	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
1055529001589	TonB family C-terminal domain; Region: tonB_Cterm; TIGR01352
1055529001590	flagellar motor switch protein; Validated; Region: PRK08433
1055529001591	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
1055529001592	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1055529001593	minor groove reading motif; other site
1055529001594	helix-hairpin-helix signature motif; other site
1055529001595	substrate binding pocket [chemical binding]; other site
1055529001596	active site
1055529001597	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1055529001598	Fe2+ transport system protein A [Inorganic ion transport and metabolism]; Region: FeoA; COG1918
1055529001599	Protein of unknown function; Region: DUF3971; pfam13116
1055529001600	AsmA-like C-terminal region; Region: AsmA_1; pfam13109
1055529001601	Aminodeoxychorismate lyase [Coenzyme transport and metabolism]; Region: COG1559
1055529001602	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
1055529001603	dimerization interface [polypeptide binding]; other site
1055529001604	2-oxoglutarate-acceptor oxidoreductase subunit OorD; Reviewed; Region: oorD; PRK09626
1055529001605	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1055529001606	2-oxoglutarate-acceptor oxidoreductase subunit OorA; Reviewed; Region: oorA; PRK09627
1055529001607	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
1055529001608	dimer interface [polypeptide binding]; other site
1055529001609	PYR/PP interface [polypeptide binding]; other site
1055529001610	TPP binding site [chemical binding]; other site
1055529001611	substrate binding site [chemical binding]; other site
1055529001612	2-oxoglutarate-acceptor oxidoreductase subunit OorB; Reviewed; Region: oorB; PRK09628
1055529001613	Thiamine pyrophosphate (TPP family), 2-oxoglutarate ferredoxin oxidoreductase (OGFOR) subfamily, TPP-binding module; OGFOR catalyzes the oxidative decarboxylation of 2-oxo-acids, with ferredoxin acting as an electron acceptor. In the TCA cycle, OGFOR...; Region: TPP_OGFOR; cd03375
1055529001614	TPP-binding site [chemical binding]; other site
1055529001615	2-oxoglutarate-acceptor oxidoreductase subunit OorC; Reviewed; Region: oorC; PRK08441
1055529001616	2-oxoglutarate ferredoxin oxidoreductase subunit gamma; Validated; Region: PRK08537
1055529001617	Disulfide bond formation protein DsbB [Posttranslational modification, protein turnover, chaperones]; Region: DsbB; COG1495
1055529001618	tumor necrosis factor alpha-inducing protein; Reviewed; Region: PRK12303
1055529001619	Transglycosylase; Region: Transgly; pfam00912
1055529001620	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
1055529001621	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1055529001622	7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism]; Region: BioF; COG0156
1055529001623	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
1055529001624	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1055529001625	catalytic residue [active]
1055529001626	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1055529001627	dimer interface [polypeptide binding]; other site
1055529001628	putative CheW interface [polypeptide binding]; other site
1055529001629	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
1055529001630	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1055529001631	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1055529001632	Walker A/P-loop; other site
1055529001633	ATP binding site [chemical binding]; other site
1055529001634	Q-loop/lid; other site
1055529001635	ABC transporter signature motif; other site
1055529001636	Walker B; other site
1055529001637	D-loop; other site
1055529001638	H-loop/switch region; other site
1055529001639	flagellin A; Reviewed; Region: PRK12584
1055529001640	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1055529001641	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
1055529001642	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
1055529001643	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1055529001644	3-methyladenine DNA glycosylase; Provisional; Region: PRK13913
1055529001645	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1055529001646	minor groove reading motif; other site
1055529001647	helix-hairpin-helix signature motif; other site
1055529001648	active site
1055529001649	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
1055529001650	substrate binding site [chemical binding]; other site
1055529001651	active site
1055529001652	Outer membrane efflux protein; Region: OEP; pfam02321
1055529001653	Outer membrane efflux protein; Region: OEP; pfam02321
1055529001654	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1055529001655	HlyD family secretion protein; Region: HlyD_3; pfam13437
1055529001656	AcrB/AcrD/AcrF family; Region: ACR_tran; pfam00873
1055529001657	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529001658	PPE-repeat proteins [Cell motility and secretion]; Region: COG5651
1055529001659	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
1055529001660	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
1055529001661	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
1055529001662	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
1055529001663	PPE-repeat proteins [Cell motility and secretion]; Region: COG5651
1055529001664	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
1055529001665	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1055529001666	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1055529001667	Walker B; other site
1055529001668	D-loop; other site
1055529001669	H-loop/switch region; other site
1055529001670	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
1055529001671	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
1055529001672	nucleotide binding pocket [chemical binding]; other site
1055529001673	K-X-D-G motif; other site
1055529001674	catalytic site [active]
1055529001675	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1055529001676	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
1055529001677	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1055529001678	Dimer interface [polypeptide binding]; other site
1055529001679	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cd00588
1055529001680	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1055529001681	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1055529001682	active site
1055529001683	phosphorylation site [posttranslational modification]
1055529001684	intermolecular recognition site; other site
1055529001685	dimerization interface [polypeptide binding]; other site
1055529001686	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1055529001687	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1055529001688	dimer interface [polypeptide binding]; other site
1055529001689	anticodon binding site; other site
1055529001690	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1055529001691	homodimer interface [polypeptide binding]; other site
1055529001692	motif 1; other site
1055529001693	active site
1055529001694	motif 2; other site
1055529001695	GAD domain; Region: GAD; pfam02938
1055529001696	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1055529001697	active site
1055529001698	motif 3; other site
1055529001699	adenylate kinase; Reviewed; Region: adk; PRK00279
1055529001700	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1055529001701	AMP-binding site [chemical binding]; other site
1055529001702	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1055529001703	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
1055529001704	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cl01298
1055529001705	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
1055529001706	Glycosyltransferase involved in LPS biosynthesis [Cell envelope biogenesis, outer membrane]; Region: COG3306
1055529001707	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
1055529001708	dimer interface [polypeptide binding]; other site
1055529001709	substrate binding site [chemical binding]; other site
1055529001710	metal binding sites [ion binding]; metal-binding site
1055529001711	MutS2 family protein; Region: mutS2; TIGR01069
1055529001712	ATPase domain of DNA mismatch repair MUTS family; Region: MUTSac; smart00534
1055529001713	Walker A/P-loop; other site
1055529001714	ATP binding site [chemical binding]; other site
1055529001715	Q-loop/lid; other site
1055529001716	ABC transporter signature motif; other site
1055529001717	Walker B; other site
1055529001718	D-loop; other site
1055529001719	H-loop/switch region; other site
1055529001720	Smr domain; Region: Smr; pfam01713
1055529001721	UDP-N-acetylmuramate--alanine ligase; Region: murC; TIGR01082
1055529001722	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1055529001723	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1055529001724	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1055529001725	hypothetical protein; Provisional; Region: PRK05839
1055529001726	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1055529001727	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1055529001728	homodimer interface [polypeptide binding]; other site
1055529001729	catalytic residue [active]
1055529001730	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
1055529001731	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1055529001732	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1055529001733	Tetrahydrodipicolinate N-succinyltransferase [Amino acid transport and metabolism]; Region: DapD; COG2171
1055529001734	Putative 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (THP succinyltransferase), C-terminal left-handed parallel alpha-helix (LbH) domain: This group is composed of mostly uncharacterized proteins containing an N-terminal...; Region: LbH_THP_succinylT_putative; cd04649
1055529001735	putative trimer interface [polypeptide binding]; other site
1055529001736	putative CoA binding site [chemical binding]; other site
1055529001737	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1055529001738	Sel1-like repeats; Region: SEL1; smart00671
1055529001739	Sel1-like repeats; Region: SEL1; smart00671
1055529001740	Sel1-like repeats; Region: SEL1; smart00671
1055529001741	Uncharacterized conserved protein [Function unknown]; Region: COG1479
1055529001742	Protein of unknown function DUF262; Region: DUF262; pfam03235
1055529001743	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
1055529001744	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
1055529001745	hydrogenase (NiFe) small subunit (hydA); Region: hydA; TIGR00391
1055529001746	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
1055529001747	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
1055529001748	Nickel-dependent hydrogenase; Region: NiFeSe_Hases; pfam00374
1055529001749	Ni,Fe-hydrogenase I cytochrome b subunit [Energy production and conversion]; Region: HyaC; COG1969
1055529001750	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
1055529001751	nickel binding site [ion binding]; other site
1055529001752	putative substrate-binding site; other site
1055529001753	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529001754	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
1055529001755	Ligand Binding Site [chemical binding]; other site
1055529001756	tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; Region: PcnB; COG0617
1055529001757	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1055529001758	active site
1055529001759	NTP binding site [chemical binding]; other site
1055529001760	metal binding triad [ion binding]; metal-binding site
1055529001761	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1055529001762	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
1055529001763	dimer interface [polypeptide binding]; other site
1055529001764	FMN binding site [chemical binding]; other site
1055529001765	glutamylglutaminyl-tRNA synthetase; Provisional; Region: PRK12410
1055529001766	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1055529001767	active site
1055529001768	HIGH motif; other site
1055529001769	nucleotide binding site [chemical binding]; other site
1055529001770	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1055529001771	active site
1055529001772	KMSKS motif; other site
1055529001773	YGGT family; Region: YGGT; pfam02325
1055529001774	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1055529001775	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1055529001776	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1055529001777	catalytic residue [active]
1055529001778	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1055529001779	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1055529001780	active site
1055529001781	tetramer interface; other site
1055529001782	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1055529001783	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1055529001784	hinge; other site
1055529001785	active site
1055529001786	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
1055529001787	Aspartase; Region: Aspartase; cd01357
1055529001788	active sites [active]
1055529001789	tetramer interface [polypeptide binding]; other site
1055529001790	Uracil-DNA glycosylases (UDG) and related enzymes; Region: UDG_like; cl00483
1055529001791	ligand binding site [chemical binding]; other site
1055529001792	active site
1055529001793	Glycosyltransferase family 10 (fucosyltransferase); Region: Glyco_transf_10; pfam00852
1055529001794	phosphoserine phosphatase SerB; Region: serB; TIGR00338
1055529001795	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1055529001796	motif II; other site
1055529001797	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
1055529001798	Ferritin-like domain; Region: Ferritin; pfam00210
1055529001799	ferroxidase diiron center [ion binding]; other site
1055529001800	hypothetical protein; Provisional; Region: PRK08444
1055529001801	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1055529001802	FeS/SAM binding site; other site
1055529001803	Outer membrane protein/protective antigen OMA87 [Cell envelope biogenesis, outer membrane]; Region: COG4775
1055529001804	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1055529001805	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1055529001806	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1055529001807	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1055529001808	Surface antigen; Region: Bac_surface_Ag; pfam01103
1055529001809	hypothetical protein; Provisional; Region: PRK08445
1055529001810	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1055529001811	FeS/SAM binding site; other site
1055529001812	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1055529001813	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1055529001814	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1055529001815	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
1055529001816	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
1055529001817	GatB domain; Region: GatB_Yqey; smart00845
1055529001818	SurA N-terminal domain; Region: SurA_N; pfam09312
1055529001819	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
1055529001820	Predicted nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module [General function prediction only]; Region: COG1439
1055529001821	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
1055529001822	RNA/DNA hybrid binding site [nucleotide binding]; other site
1055529001823	active site
1055529001824	ribonuclease III; Reviewed; Region: rnc; PRK00102
1055529001825	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1055529001826	dimerization interface [polypeptide binding]; other site
1055529001827	active site
1055529001828	metal binding site [ion binding]; metal-binding site
1055529001829	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1055529001830	dsRNA binding site [nucleotide binding]; other site
1055529001831	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
1055529001832	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
1055529001833	Tetramer interface [polypeptide binding]; other site
1055529001834	active site
1055529001835	FMN-binding site [chemical binding]; other site
1055529001836	Protein of unknown function (DUF2603); Region: DUF2603; pfam10788
1055529001837	oxygen-independent coproporphyrinogen III oxidase; Region: hemN; TIGR00538
1055529001838	RNase PH-like 3'-5' exoribonucleases; Region: RNase_PH; cl03114
1055529001839	HemN C-terminal domain; Region: HemN_C; pfam06969
1055529001840	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1055529001841	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1055529001842	Cysteine-rich domain; Region: CCG; pfam02754
1055529001843	Cysteine-rich domain; Region: CCG; pfam02754
1055529001844	Restriction endonuclease; Region: Mrr_cat_2; pfam13156
1055529001845	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1055529001846	ATP binding site [chemical binding]; other site
1055529001847	putative Mg++ binding site [ion binding]; other site
1055529001848	Predicted helicase [General function prediction only]; Region: COG4889
1055529001849	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1055529001850	nucleotide binding region [chemical binding]; other site
1055529001851	ATP-binding site [chemical binding]; other site
1055529001852	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529001853	aspartate aminotransferase; Provisional; Region: PRK05764
1055529001854	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1055529001855	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1055529001856	homodimer interface [polypeptide binding]; other site
1055529001857	catalytic residue [active]
1055529001858	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
1055529001859	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1055529001860	active site
1055529001861	DNA binding site [nucleotide binding]
1055529001862	Int/Topo IB signature motif; other site
1055529001863	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1055529001864	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
1055529001865	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1055529001866	DNA binding site [nucleotide binding]
1055529001867	active site
1055529001868	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1055529001869	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1055529001870	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1055529001871	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1055529001872	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08447
1055529001873	ATP cone domain; Region: ATP-cone; pfam03477
1055529001874	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1055529001875	active site
1055529001876	dimer interface [polypeptide binding]; other site
1055529001877	catalytic residues [active]
1055529001878	effector binding site; other site
1055529001879	R2 peptide binding site; other site
1055529001880	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14359
1055529001881	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
1055529001882	Substrate binding site; other site
1055529001883	Mg++ binding site; other site
1055529001884	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
1055529001885	active site
1055529001886	substrate binding site [chemical binding]; other site
1055529001887	CoA binding site [chemical binding]; other site
1055529001888	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
1055529001889	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
1055529001890	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1055529001891	N-terminal plug; other site
1055529001892	ligand-binding site [chemical binding]; other site
1055529001893	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
1055529001894	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
1055529001895	G1 box; other site
1055529001896	GTP/Mg2+ binding site [chemical binding]; other site
1055529001897	Switch I region; other site
1055529001898	G2 box; other site
1055529001899	G3 box; other site
1055529001900	Switch II region; other site
1055529001901	G4 box; other site
1055529001902	G5 box; other site
1055529001903	Nucleoside recognition; Region: Gate; pfam07670
1055529001904	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
1055529001905	Nucleoside recognition; Region: Gate; pfam07670
1055529001906	Uncharacterized bacterial subgroup of the DEDDy 3'-5' exonuclease domain of family-B DNA polymerases; Region: DNA_polB_like1_exo; cd05782
1055529001907	active site
1055529001908	catalytic site [active]
1055529001909	substrate binding site [chemical binding]; other site
1055529001910	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB; Region: DNA_pol_B_exo2; pfam10108
1055529001911	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1055529001912	DNA methylase; Region: N6_N4_Mtase; pfam01555
1055529001913	CfrBI restriction endonuclease; Region: RE_CfrBI; pfam09516
1055529001914	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB [DNA replication, recombination, and repair]; Region: COG3298
1055529001915	putative acyltransferase; Provisional; Region: PRK05790
1055529001916	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1055529001917	dimer interface [polypeptide binding]; other site
1055529001918	active site
1055529001919	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788
1055529001920	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
1055529001921	Short chain fatty acid transporter; Region: SCFA_trans; pfam02667
1055529001922	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3528
1055529001923	N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuA; COG0145
1055529001924	Hydantoinase/oxoprolinase N-terminal region; Region: Hydant_A_N; pfam05378
1055529001925	Hydantoinase/oxoprolinase; Region: Hydantoinase_A; pfam01968
1055529001926	N-methylhydantoinase B/acetone carboxylase, alpha subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuB; COG0146
1055529001927	Hydantoinase B/oxoprolinase; Region: Hydantoinase_B; pfam02538
1055529001928	Acetone carboxylase, gamma subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcxC; COG4647
1055529001929	Acetone carboxylase gamma subunit; Region: Acetone_carb_G; pfam08882
1055529001930	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
1055529001931	DNA gyrase subunit A; Validated; Region: PRK05560
1055529001932	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1055529001933	CAP-like domain; other site
1055529001934	active site
1055529001935	primary dimer interface [polypeptide binding]; other site
1055529001936	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1055529001937	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1055529001938	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1055529001939	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1055529001940	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1055529001941	Response regulator receiver domain; Region: Response_reg; pfam00072
1055529001942	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1055529001943	active site
1055529001944	phosphorylation site [posttranslational modification]
1055529001945	intermolecular recognition site; other site
1055529001946	dimerization interface [polypeptide binding]; other site
1055529001947	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1055529001948	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1055529001949	Walker A motif; other site
1055529001950	ATP binding site [chemical binding]; other site
1055529001951	Walker B motif; other site
1055529001952	arginine finger; other site
1055529001953	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1055529001954	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1055529001955	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1055529001956	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1055529001957	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529001958	Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG0275
1055529001959	16S rRNA (cytosine(1402)-N(4))-methyltransferase; Region: TIGR00006
1055529001960	Uncharacterized conserved protein [Function unknown]; Region: COG1912
1055529001961	Competence protein ComGF [Intracellular trafficking and secretion]; Region: ComGF; COG4940
1055529001962	Predicted hydrolases of HD superfamily [General function prediction only]; Region: COG1896
1055529001963	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
1055529001964	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
1055529001965	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
1055529001966	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
1055529001967	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
1055529001968	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
1055529001969	Walker A/P-loop; other site
1055529001970	ATP binding site [chemical binding]; other site
1055529001971	Q-loop/lid; other site
1055529001972	ABC transporter signature motif; other site
1055529001973	Walker B; other site
1055529001974	D-loop; other site
1055529001975	H-loop/switch region; other site
1055529001976	Uncharacterized P-loop hydrolase UPF0079; Region: UPF0079; cl00520
1055529001977	DNA polymerase III subunits gamma and tau; Validated; Region: PRK08451
1055529001978	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1055529001979	Walker A motif; other site
1055529001980	ATP binding site [chemical binding]; other site
1055529001981	Walker B motif; other site
1055529001982	arginine finger; other site
1055529001983	Lysine efflux permease [General function prediction only]; Region: COG1279
1055529001984	Protein of unknown function (DUF1104); Region: DUF1104; pfam06518
1055529001985	Protein of unknown function (DUF1104); Region: DUF1104; pfam06518
1055529001986	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
1055529001987	active site
1055529001988	homodimer interface [polypeptide binding]; other site
1055529001989	homotetramer interface [polypeptide binding]; other site
1055529001990	anaerobic c4-dicarboxylate membrane transporter family protein; Region: Dcu; TIGR00770
1055529001991	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1055529001992	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529001993	tRNA-dihydrouridine synthase [Translation, ribosomal structure and biogenesis]; Region: COG0042
1055529001994	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1055529001995	FMN binding site [chemical binding]; other site
1055529001996	active site
1055529001997	catalytic residues [active]
1055529001998	substrate binding site [chemical binding]; other site
1055529001999	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
1055529002000	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1055529002001	Ligand Binding Site [chemical binding]; other site
1055529002002	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
1055529002003	putative oxidoreductase; Provisional; Region: PRK13984
1055529002004	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1055529002005	G1 box; other site
1055529002006	GTP/Mg2+ binding site [chemical binding]; other site
1055529002007	G2 box; other site
1055529002008	Switch I region; other site
1055529002009	G3 box; other site
1055529002010	Switch II region; other site
1055529002011	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
1055529002012	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1055529002013	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1055529002014	FeS/SAM binding site; other site
1055529002015	Predicted phosphoribosyltransferases [General function prediction only]; Region: COG2236
1055529002016	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1055529002017	active site
1055529002018	Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075
1055529002019	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1055529002020	catalytic residue [active]
1055529002021	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
1055529002022	tetramer interfaces [polypeptide binding]; other site
1055529002023	binuclear metal-binding site [ion binding]; other site
1055529002024	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
1055529002025	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1055529002026	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1055529002027	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1055529002028	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
1055529002029	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1055529002030	FHIT (fragile histidine family): FHIT proteins, related to the HIT family carry a motif HxHxH/Qxx (x, is a hydrophobic amino acid), On the basis of sequence, substrate specificity, structure, evolution and mechanism, HIT proteins are classified into...; Region: FHIT; cd01275
1055529002031	nucleotide binding site/active site [active]
1055529002032	HIT family signature motif; other site
1055529002033	catalytic residue [active]
1055529002034	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
1055529002035	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1055529002036	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1055529002037	active site
1055529002038	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
1055529002039	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1055529002040	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1055529002041	active site
1055529002042	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1055529002043	Fibronectin type 3 domain-containing protein [General function prediction only]; Region: COG3401
1055529002044	Interdomain contacts; other site
1055529002045	Cytokine receptor motif; other site
1055529002046	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1055529002047	Interdomain contacts; other site
1055529002048	Cytokine receptor motif; other site
1055529002049	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1055529002050	Interdomain contacts; other site
1055529002051	Cytokine receptor motif; other site
1055529002052	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1055529002053	S-adenosylmethionine binding site [chemical binding]; other site
1055529002054	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1055529002055	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1055529002056	Walker A/P-loop; other site
1055529002057	ATP binding site [chemical binding]; other site
1055529002058	Q-loop/lid; other site
1055529002059	ABC transporter signature motif; other site
1055529002060	Walker B; other site
1055529002061	D-loop; other site
1055529002062	H-loop/switch region; other site
1055529002063	Cell division protein [Cell division and chromosome partitioning]; Region: FtsX; COG2177
1055529002064	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1055529002065	Peptidase family M23; Region: Peptidase_M23; pfam01551
1055529002066	flagellar protein FlaG; Provisional; Region: PRK08452
1055529002067	flagellar capping protein; Validated; Region: fliD; PRK08453
1055529002068	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
1055529002069	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
1055529002070	flagellar biosynthetic protein FliS; Region: fliS; TIGR00208
1055529002071	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism]; Region: COG1179
1055529002072	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
1055529002073	putative ATP binding site [chemical binding]; other site
1055529002074	putative substrate interface [chemical binding]; other site
1055529002075	N-carbamoylputrescine amidohydrolase (CPA) (class 11 nitrilases); Region: CPA; cd07573
1055529002076	N-carbamoylputrescine amidase; Region: agmatine_aguB; TIGR03381
1055529002077	putative active site; other site
1055529002078	catalytic triad [active]
1055529002079	putative dimer interface [polypeptide binding]; other site
1055529002080	Predicted permease [General function prediction only]; Region: COG2056
1055529002081	Na+-H+ antiporter family; Region: Na_H_antiport_2; pfam13726
1055529002082	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
1055529002083	putative efflux protein, MATE family; Region: matE; TIGR00797
1055529002084	phosphodiesterase; Provisional; Region: PRK12704
1055529002085	K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; Region: KH-I; cd00105
1055529002086	nucleic acid binding region [nucleotide binding]; other site
1055529002087	G-X-X-G motif; other site
1055529002088	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1055529002089	Zn2+ binding site [ion binding]; other site
1055529002090	Mg2+ binding site [ion binding]; other site
1055529002091	5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism]; Region: COG0212; cl00360
1055529002092	histidinol phosphate phosphatase, HisJ family; Region: hisJ_fam; TIGR01856
1055529002093	signal recognition particle-docking protein FtsY; Region: ftsY; TIGR00064
1055529002094	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1055529002095	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
1055529002096	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1055529002097	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
1055529002098	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1055529002099	FeS/SAM binding site; other site
1055529002100	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
1055529002101	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
1055529002102	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
1055529002103	GTP binding site; other site
1055529002104	flagellar biosynthetic protein FlhB; Region: flhB; TIGR00328
1055529002105	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
1055529002106	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1055529002107	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1055529002108	active site
1055529002109	metal binding site [ion binding]; metal-binding site
1055529002110	Nitronate monooxygenase; Region: NMO; pfam03060
1055529002111	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
1055529002112	FMN binding site [chemical binding]; other site
1055529002113	substrate binding site [chemical binding]; other site
1055529002114	putative catalytic residue [active]
1055529002115	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
1055529002116	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1055529002117	active site
1055529002118	HIGH motif; other site
1055529002119	dimer interface [polypeptide binding]; other site
1055529002120	KMSKS motif; other site
1055529002121	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1055529002122	RNA binding surface [nucleotide binding]; other site
1055529002123	(p)ppGpp synthetase, RelA/SpoT family; Region: spoT_relA; TIGR00691
1055529002124	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1055529002125	Zn2+ binding site [ion binding]; other site
1055529002126	Mg2+ binding site [ion binding]; other site
1055529002127	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1055529002128	synthetase active site [active]
1055529002129	NTP binding site [chemical binding]; other site
1055529002130	metal binding site [ion binding]; metal-binding site
1055529002131	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1055529002132	DNA-directed RNA polymerase, subunit K/omega [Transcription]; Region: RpoZ; COG1758
1055529002133	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1055529002134	putative nucleotide binding site [chemical binding]; other site
1055529002135	uridine monophosphate binding site [chemical binding]; other site
1055529002136	homohexameric interface [polypeptide binding]; other site
1055529002137	Predicted periplasmic solute-binding protein [General function prediction only]; Region: COG1427
1055529002138	aconitate hydratase 2; Region: acnB; TIGR00117
1055529002139	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
1055529002140	substrate binding site [chemical binding]; other site
1055529002141	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
1055529002142	substrate binding site [chemical binding]; other site
1055529002143	ligand binding site [chemical binding]; other site
1055529002144	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
1055529002145	FOG: Transposase [DNA replication, recombination, and repair]; Region: COG5659
1055529002146	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
1055529002147	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
1055529002148	Outer membrane lipoprotein carrier protein LolA; Region: LolA; pfam03548
1055529002149	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
1055529002150	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1055529002151	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1055529002152	nucleotide binding region [chemical binding]; other site
1055529002153	ATP-binding site [chemical binding]; other site
1055529002154	SEC-C motif; Region: SEC-C; pfam02810
1055529002155	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
1055529002156	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1055529002157	FtsX-like permease family; Region: FtsX; pfam02687
1055529002158	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
1055529002159	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1055529002160	cofactor binding site; other site
1055529002161	DNA binding site [nucleotide binding]
1055529002162	substrate interaction site [chemical binding]; other site
1055529002163	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1055529002164	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cl00207
1055529002165	metal-binding site [ion binding]
1055529002166	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
1055529002167	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1055529002168	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1055529002169	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
1055529002170	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1055529002171	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
1055529002172	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
1055529002173	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1055529002174	active site
1055529002175	catalytic residues [active]
1055529002176	metal binding site [ion binding]; metal-binding site
1055529002177	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
1055529002178	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1055529002179	oligomer interface [polypeptide binding]; other site
1055529002180	active site residues [active]
1055529002181	trigger factor; Provisional; Region: tig; PRK01490
1055529002182	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1055529002183	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1055529002184	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529002185	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
1055529002186	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
1055529002187	trimer interface [polypeptide binding]; other site
1055529002188	dimer interface [polypeptide binding]; other site
1055529002189	putative active site [active]
1055529002190	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1055529002191	MPT binding site; other site
1055529002192	trimer interface [polypeptide binding]; other site
1055529002193	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
1055529002194	MoaE homodimer interface [polypeptide binding]; other site
1055529002195	MoaD interaction [polypeptide binding]; other site
1055529002196	active site residues [active]
1055529002197	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
1055529002198	MoaE interaction surface [polypeptide binding]; other site
1055529002199	MoeB interaction surface [polypeptide binding]; other site
1055529002200	thiocarboxylated glycine; other site
1055529002201	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
1055529002202	dimerization interface [polypeptide binding]; other site
1055529002203	active site
1055529002204	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09314
1055529002205	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: ribB; TIGR00506
1055529002206	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cl00522
1055529002207	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
1055529002208	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
1055529002209	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; cl00500
1055529002210	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK08455
1055529002211	RNA methyltransferase, RsmD family; Region: TIGR00095
1055529002212	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
1055529002213	Uncharacterized conserved protein [Function unknown]; Region: COG1565
1055529002214	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1055529002215	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 [Coenzyme metabolism]; Region: ThiF; COG0476
1055529002216	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1055529002217	ATP binding site [chemical binding]; other site
1055529002218	substrate interface [chemical binding]; other site
1055529002219	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
1055529002220	flagellar motor protein MotA; Validated; Region: PRK08456
1055529002221	flagellar motor protein MotB; Reviewed; Region: motB; PRK08457
1055529002222	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1055529002223	ligand binding site [chemical binding]; other site
1055529002224	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1055529002225	dimer interface [polypeptide binding]; other site
1055529002226	conserved gate region; other site
1055529002227	ABC-ATPase subunit interface; other site
1055529002228	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
1055529002229	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1055529002230	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1055529002231	Walker A/P-loop; other site
1055529002232	ATP binding site [chemical binding]; other site
1055529002233	Q-loop/lid; other site
1055529002234	ABC transporter signature motif; other site
1055529002235	Walker B; other site
1055529002236	D-loop; other site
1055529002237	H-loop/switch region; other site
1055529002238	excinuclease ABC, C subunit; Region: uvrC; TIGR00194
1055529002239	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1055529002240	GIY-YIG motif/motif A; other site
1055529002241	active site
1055529002242	catalytic site [active]
1055529002243	putative DNA binding site [nucleotide binding]; other site
1055529002244	metal binding site [ion binding]; metal-binding site
1055529002245	UvrB/uvrC motif; Region: UVR; pfam02151
1055529002246	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1055529002247	homoserine dehydrogenase; Provisional; Region: PRK06349
1055529002248	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1055529002249	ACT_HSDH_Hom CD includes the C-terminal ACT domain of the NAD(P)H-dependent, homoserine dehydrogenase (HSDH) and related domains; Region: ACT_HSDH-Hom; cd04881
1055529002250	Predicted endonuclease distantly related to archaeal Holliday junction resolvase [DNA replication, recombination, and repair]; Region: COG0792
1055529002251	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1055529002252	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1055529002253	catalytic residues [active]
1055529002254	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
1055529002255	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1055529002256	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1055529002257	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
1055529002258	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cl01298
1055529002259	RNA recognition motif in Helicobacter pylori HP0827 protein and similar proteins; Region: RRM_HP0827_like; cd12399
1055529002260	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
1055529002261	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
1055529002262	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
1055529002263	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1055529002264	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
1055529002265	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1055529002266	active site
1055529002267	aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit; Region: gatA; TIGR00132
1055529002268	indole acetimide hydrolase; Validated; Region: PRK07488
1055529002269	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
1055529002270	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1055529002271	CoA-binding site [chemical binding]; other site
1055529002272	spermidine synthase; Provisional; Region: speE; PRK00536
1055529002273	spermidine synthase; Provisional; Region: PRK00811
1055529002274	GTP-binding protein Der; Reviewed; Region: PRK00093
1055529002275	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1055529002276	G1 box; other site
1055529002277	GTP/Mg2+ binding site [chemical binding]; other site
1055529002278	Switch I region; other site
1055529002279	G2 box; other site
1055529002280	Switch II region; other site
1055529002281	G3 box; other site
1055529002282	G4 box; other site
1055529002283	G5 box; other site
1055529002284	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1055529002285	G1 box; other site
1055529002286	GTP/Mg2+ binding site [chemical binding]; other site
1055529002287	Switch I region; other site
1055529002288	G2 box; other site
1055529002289	G3 box; other site
1055529002290	Switch II region; other site
1055529002291	G4 box; other site
1055529002292	G5 box; other site
1055529002293	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1055529002294	IHF dimer interface [polypeptide binding]; other site
1055529002295	IHF - DNA interface [nucleotide binding]; other site
1055529002296	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3018
1055529002297	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3018
1055529002298	Long-chain fatty acid transport protein [Lipid metabolism]; Region: FadL; COG2067
1055529002299	UDP-N-acetylglucosamine 4,6-dehydratase; Region: PseB; TIGR03589
1055529002300	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
1055529002301	NAD(P) binding site [chemical binding]; other site
1055529002302	homodimer interface [polypeptide binding]; other site
1055529002303	substrate binding site [chemical binding]; other site
1055529002304	active site
1055529002305	phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; Region: coaBC_dfp; TIGR00521
1055529002306	Flavoprotein; Region: Flavoprotein; pfam02441
1055529002307	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
1055529002308	Alpha-2,3-sialyltransferase (CST-I); Region: CST-I; pfam06002
1055529002309	Alpha-2,3-sialyltransferase (CST-I); Region: CST-I; pfam06002
1055529002310	CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513
1055529002311	ligand binding site; other site
1055529002312	tetramer interface; other site
1055529002313	UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing; Region: NeuC_NnaA; TIGR03568
1055529002314	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1055529002315	active site
1055529002316	homodimer interface [polypeptide binding]; other site
1055529002317	N-acetylneuraminate synthase; Region: NeuB_NnaB; TIGR03569
1055529002318	NeuB family; Region: NeuB; pfam03102
1055529002319	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
1055529002320	NeuB binding interface [polypeptide binding]; other site
1055529002321	putative substrate binding site [chemical binding]; other site
1055529002322	type I site-specific deoxyribonuclease, HsdR family; Region: hsdR; TIGR00348
1055529002323	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
1055529002324	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1055529002325	ATP binding site [chemical binding]; other site
1055529002326	putative Mg++ binding site [ion binding]; other site
1055529002327	Type I restriction and modification enzyme - subunit R C terminal; Region: EcoR124_C; pfam12008
1055529002328	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1055529002329	thiamine phosphate binding site [chemical binding]; other site
1055529002330	active site
1055529002331	pyrophosphate binding site [ion binding]; other site
1055529002332	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
1055529002333	dimer interface [polypeptide binding]; other site
1055529002334	substrate binding site [chemical binding]; other site
1055529002335	ATP binding site [chemical binding]; other site
1055529002336	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
1055529002337	substrate binding site [chemical binding]; other site
1055529002338	multimerization interface [polypeptide binding]; other site
1055529002339	ATP binding site [chemical binding]; other site
1055529002340	HsdM N-terminal domain; Region: HsdM_N; pfam12161
1055529002341	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1055529002342	C-5 cytosine-specific DNA methylase; Region: DNA_methylase; pfam00145
1055529002343	cofactor binding site; other site
1055529002344	DNA binding site [nucleotide binding]
1055529002345	substrate interaction site [chemical binding]; other site
1055529002346	HaeIII restriction endonuclease; Region: RE_HaeIII; pfam09556
1055529002347	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
1055529002348	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1055529002349	active site
1055529002350	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2958
1055529002351	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
1055529002352	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1055529002353	Walker A/P-loop; other site
1055529002354	ATP binding site [chemical binding]; other site
1055529002355	Q-loop/lid; other site
1055529002356	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1055529002357	ABC transporter; Region: ABC_tran_2; pfam12848
1055529002358	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1055529002359	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05458
1055529002360	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1055529002361	active site
1055529002362	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1055529002363	dimer interface [polypeptide binding]; other site
1055529002364	active site
1055529002365	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaE; COG2870
1055529002366	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
1055529002367	putative ribose interaction site [chemical binding]; other site
1055529002368	putative ADP binding site [chemical binding]; other site
1055529002369	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
1055529002370	active site
1055529002371	nucleotide binding site [chemical binding]; other site
1055529002372	HIGH motif; other site
1055529002373	KMSKS motif; other site
1055529002374	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1055529002375	ADP-L-glycero-D-manno-heptose-6-epimerase; Region: heptose_epim; TIGR02197
1055529002376	NAD(P) binding site [chemical binding]; other site
1055529002377	active site
1055529002378	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
1055529002379	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1055529002380	active site
1055529002381	motif I; other site
1055529002382	motif II; other site
1055529002383	Uncharacterized conserved protein [Function unknown]; Region: COG2836
1055529002384	pantothenate kinase; Reviewed; Region: PRK13333
1055529002385	PQQ-like domain; Region: PQQ_2; pfam13360
1055529002386	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1055529002387	trimer interface [polypeptide binding]; other site
1055529002388	active site
1055529002389	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1055529002390	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1055529002391	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1055529002392	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
1055529002393	lipid-A-disaccharide synthase; Region: lpxB; TIGR00215
1055529002394	hydrogenase nickel incorporation protein; Provisional; Region: hypA; PRK00564
1055529002395	Hydrogenase expression/synthesis hypA family; Region: HypA; pfam01155
1055529002396	flagellar hook protein FlgE; Validated; Region: flgE; PRK08425
1055529002397	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1055529002398	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
1055529002399	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
1055529002400	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1055529002401	CDP-diacylglycerol pyrophosphatase, bacterial type; Region: cdh; TIGR00672
1055529002402	Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824
1055529002403	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
1055529002404	PhnA protein; Region: PhnA; pfam03831
1055529002405	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
1055529002406	Clade 3 of the heme-binding enzyme catalase; Region: catalase_clade_3; cd08156
1055529002407	tetramer interface [polypeptide binding]; other site
1055529002408	heme binding pocket [chemical binding]; other site
1055529002409	NADPH binding site [chemical binding]; other site
1055529002410	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1055529002411	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1055529002412	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1055529002413	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
1055529002414	active site
1055529002415	putative DNA-binding cleft [nucleotide binding]; other site
1055529002416	dimer interface [polypeptide binding]; other site
1055529002417	Uncharacterized conserved protein [Function unknown]; Region: COG1432
1055529002418	LabA_like proteins; Region: LabA_like; cd06167
1055529002419	putative metal binding site [ion binding]; other site
1055529002420	Protein of unknown function (DUF3519); Region: DUF3519; pfam12033
1055529002421	Holliday junction DNA helicase, RuvA subunit; Region: ruvA; TIGR00084
1055529002422	RuvA N terminal domain; Region: RuvA_N; pfam01330
1055529002423	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
1055529002424	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
1055529002425	MviN-like protein; Region: MVIN; pfam03023
1055529002426	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1055529002427	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1055529002428	active site
1055529002429	HIGH motif; other site
1055529002430	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1055529002431	KMSKS motif; other site
1055529002432	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1055529002433	tRNA binding surface [nucleotide binding]; other site
1055529002434	anticodon binding site; other site
1055529002435	Vacuolating cyotoxin; Region: VacA; pfam02691
1055529002436	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1055529002437	potential frameshift: common BLAST hit: gi|15611887|ref|NP_223538.1| putative lipopolysaccharide biosynthesis protein
1055529002438	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1055529002439	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1055529002440	Walker A/P-loop; other site
1055529002441	ATP binding site [chemical binding]; other site
1055529002442	Q-loop/lid; other site
1055529002443	ABC transporter signature motif; other site
1055529002444	Walker B; other site
1055529002445	D-loop; other site
1055529002446	H-loop/switch region; other site
1055529002447	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1055529002448	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1055529002449	ABC-ATPase subunit  interface; other site
1055529002450	dimer interface [polypeptide binding]; other site
1055529002451	putative PBP binding regions; other site
1055529002452	short chain dehydrogenase; Validated; Region: PRK06182
1055529002453	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
1055529002454	NADP binding site [chemical binding]; other site
1055529002455	active site
1055529002456	steroid binding site; other site
1055529002457	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
1055529002458	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041
1055529002459	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529002460	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
1055529002461	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
1055529002462	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypC; COG0298
1055529002463	hydrogenase accessory protein HypB; Region: hypB; TIGR00073
1055529002464	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1055529002465	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
1055529002466	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
1055529002467	propionate/acetate kinase; Provisional; Region: PRK12379
1055529002468	BioD-like N-terminal domain of phosphotransacetylase [General function prediction only]; Region: Pta; COG0857
1055529002469	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
1055529002470	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
1055529002471	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK05842
1055529002472	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
1055529002473	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
1055529002474	flagellar hook protein FlgE; Validated; Region: flgE; PRK05841
1055529002475	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1055529002476	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827
1055529002477	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1055529002478	S-adenosylmethionine binding site [chemical binding]; other site
1055529002479	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
1055529002480	Part of AAA domain; Region: AAA_19; pfam13245
1055529002481	Family description; Region: UvrD_C_2; pfam13538
1055529002482	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529002483	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529002484	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
1055529002485	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
1055529002486	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1055529002487	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1055529002488	Telomere recombination; Region: Sua5_yciO_yrdC; cl00305
1055529002489	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
1055529002490	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1055529002491	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1055529002492	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
1055529002493	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1055529002494	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1055529002495	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
1055529002496	IMP binding site; other site
1055529002497	dimer interface [polypeptide binding]; other site
1055529002498	interdomain contacts; other site
1055529002499	partial ornithine binding site; other site
1055529002500	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1055529002501	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1055529002502	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
1055529002503	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
1055529002504	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1055529002505	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
1055529002506	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
1055529002507	PPE-repeat proteins [Cell motility and secretion]; Region: COG5651
1055529002508	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
1055529002509	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1055529002510	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529002511	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cd00491
1055529002512	active site 1 [active]
1055529002513	dimer interface [polypeptide binding]; other site
1055529002514	hexamer interface [polypeptide binding]; other site
1055529002515	active site 2 [active]
1055529002516	recombination protein RecR; Region: recR; TIGR00615
1055529002517	RecR protein; Region: RecR; pfam02132
1055529002518	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
1055529002519	putative active site [active]
1055529002520	putative metal-binding site [ion binding]; other site
1055529002521	tetramer interface [polypeptide binding]; other site
1055529002522	tRNA pseudouridine synthase, TruD family; Region: tRNA_TruD_broad; TIGR00094
1055529002523	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
1055529002524	Permutation of conserved domain; other site
1055529002525	active site
1055529002526	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
1055529002527	heat shock protein HtpX; Provisional; Region: PRK02870
1055529002528	GTP cyclohydrolase I; Region: folE; TIGR00063
1055529002529	GTP cyclohydrolase I; Provisional; Region: PLN03044
1055529002530	active site
1055529002531	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1055529002532	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1055529002533	substrate binding pocket [chemical binding]; other site
1055529002534	chain length determination region; other site
1055529002535	substrate-Mg2+ binding site; other site
1055529002536	catalytic residues [active]
1055529002537	aspartate-rich region 1; other site
1055529002538	active site lid residues [active]
1055529002539	aspartate-rich region 2; other site
1055529002540	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
1055529002541	6-pyruvoyl-tetrahydropterin synthase [Coenzyme metabolism]; Region: COG0720
1055529002542	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
1055529002543	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
1055529002544	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1055529002545	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1055529002546	Coenzyme A binding pocket [chemical binding]; other site
1055529002547	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1055529002548	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529002549	potential frameshift: common BLAST hit: gi|188527759|ref|YP_001910446.1| proline and betaine transporter
1055529002550	Protein of unknown function DUF262; Region: DUF262; pfam03235
1055529002551	Uncharacterized conserved protein [Function unknown]; Region: COG1479
1055529002552	Protein of unknown function DUF262; Region: DUF262; pfam03235
1055529002553	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1055529002554	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1055529002555	dimer interface [polypeptide binding]; other site
1055529002556	conserved gate region; other site
1055529002557	putative PBP binding loops; other site
1055529002558	ABC-ATPase subunit interface; other site
1055529002559	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
1055529002560	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1055529002561	substrate binding pocket [chemical binding]; other site
1055529002562	membrane-bound complex binding site; other site
1055529002563	hinge residues; other site
1055529002564	alanine racemase; Region: alr; TIGR00492
1055529002565	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
1055529002566	active site
1055529002567	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1055529002568	dimer interface [polypeptide binding]; other site
1055529002569	substrate binding site [chemical binding]; other site
1055529002570	catalytic residues [active]
1055529002571	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1055529002572	amino acid carrier protein; Region: agcS; TIGR00835
1055529002573	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1055529002574	Streptococcal 67 kDa myosin-cross-reactive antigen like family; Region: Strep_67kDa_ant; cl17487
1055529002575	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1055529002576	homotrimer interaction site [polypeptide binding]; other site
1055529002577	putative active site [active]
1055529002578	TRL-like protein family; Region: TRL; pfam13146
1055529002579	Na+/H+ antiporter [Energy production and conversion]; Region: NhaC; COG1757
1055529002580	Uncharacterized conserved protein [Function unknown]; Region: COG1576
1055529002581	acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Region: accD; TIGR00515
1055529002582	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
1055529002583	putative recombination protein RecO; Provisional; Region: PRK13908
1055529002584	competence/damage-inducible protein CinA C-terminal domain; Region: cinA_cterm; TIGR00199
1055529002585	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
1055529002586	dimer interface [polypeptide binding]; other site
1055529002587	FMN binding site [chemical binding]; other site
1055529002588	prolipoprotein diacylglyceryl transferase; Region: lgt; TIGR00544
1055529002589	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1055529002590	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1055529002591	active site
1055529002592	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
1055529002593	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
1055529002594	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1055529002595	Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]; Region: COG1579
1055529002596	Putative zinc ribbon domain; Region: DUF164; pfam02591
1055529002597	dinuclear metal center protein, YbgI/SA1388 family; Region: YbgI_SA1388; TIGR00486
1055529002598	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1055529002599	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
1055529002600	dimer interface [polypeptide binding]; other site
1055529002601	motif 1; other site
1055529002602	active site
1055529002603	motif 2; other site
1055529002604	motif 3; other site
1055529002605	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
1055529002606	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1055529002607	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1055529002608	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1055529002609	Dynamin family; Region: Dynamin_N; pfam00350
1055529002610	G1 box; other site
1055529002611	GTP/Mg2+ binding site [chemical binding]; other site
1055529002612	G2 box; other site
1055529002613	Switch I region; other site
1055529002614	G3 box; other site
1055529002615	Switch II region; other site
1055529002616	G4 box; other site
1055529002617	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1055529002618	G1 box; other site
1055529002619	GTP/Mg2+ binding site [chemical binding]; other site
1055529002620	G2 box; other site
1055529002621	Switch I region; other site
1055529002622	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1055529002623	G3 box; other site
1055529002624	Switch II region; other site
1055529002625	G4 box; other site
1055529002626	Uncharacterized virulence-associated protein D [Function unknown]; Region: VapD; COG3309
1055529002627	Protein of unknown function (DUF3240); Region: DUF3240; pfam11582
1055529002628	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
1055529002629	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
1055529002630	HlyD family secretion protein; Region: HlyD_3; pfam13437
1055529002631	Outer membrane efflux protein; Region: OEP; pfam02321
1055529002632	glycyl-tRNA synthetase, tetrameric type, beta subunit; Region: glyS; TIGR00211
1055529002633	phosphoglyceromutase; Provisional; Region: PRK05434
1055529002634	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
1055529002635	aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit; Region: gatC; TIGR00135
1055529002636	adenosylmethionine--8-amino-7-oxononanoate transaminase; Provisional; Region: PRK05964
1055529002637	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1055529002638	inhibitor-cofactor binding pocket; inhibition site
1055529002639	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1055529002640	catalytic residue [active]
1055529002641	SurA N-terminal domain; Region: SurA_N_3; cl07813
1055529002642	peptidylprolyl isomerase; Provisional; Region: prsA; PRK00059
1055529002643	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
1055529002644	cell division protein FtsA; Region: ftsA; TIGR01174
1055529002645	Cell division protein FtsA; Region: FtsA; smart00842
1055529002646	Cell division protein FtsA; Region: FtsA; pfam14450
1055529002647	cell division protein FtsZ; Validated; Region: PRK09330
1055529002648	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1055529002649	nucleotide binding site [chemical binding]; other site
1055529002650	SulA interaction site; other site
1055529002651	potential frameshift: common BLAST hit: gi|308183130|ref|YP_003927257.1| IS606 transposase
1055529002652	potential frameshift: common BLAST hit: gi|308183130|ref|YP_003927257.1| IS606 transposase
1055529002653	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1055529002654	potential frameshift: common BLAST hit: gi|188527802|ref|YP_001910489.1| exodeoxyribonuclease VII large subunit
1055529002655	Exonuclease VII, large subunit [DNA replication, recombination, and repair]; Region: XseA; COG1570
1055529002656	potential frameshift: common BLAST hit: gi|188527802|ref|YP_001910489.1| exodeoxyribonuclease VII large subunit
1055529002657	exodeoxyribonuclease VII, large subunit; Region: xseA; TIGR00237
1055529002658	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
1055529002659	generic binding surface II; other site
1055529002660	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
1055529002661	active site
1055529002662	AAA domain; Region: AAA_33; pfam13671
1055529002663	Domain of unknown function (DUF1887); Region: DUF1887; pfam09002
1055529002664	Domain of unknown function (DUF2357); Region: DUF2357; pfam09823
1055529002665	GTPase subunit of restriction endonuclease [Defense mechanisms]; Region: McrB; COG1401
1055529002666	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
1055529002667	AAA domain; Region: AAA_12; pfam13087
1055529002668	Part of AAA domain; Region: AAA_19; pfam13245
1055529002669	Type IV secretory pathway, VirD2 components (relaxase) [Intracellular trafficking and secretion]; Region: VirD2; COG3843
1055529002670	AAA domain; Region: AAA_11; pfam13086
1055529002671	AAA domain; Region: AAA_30; pfam13604
1055529002672	AAA domain; Region: AAA_12; pfam13087
1055529002673	Protein kinase domain; Region: Pkinase; pfam00069
1055529002674	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
1055529002675	active site
1055529002676	ATP binding site [chemical binding]; other site
1055529002677	substrate binding site [chemical binding]; other site
1055529002678	activation loop (A-loop); other site
1055529002679	Protein phosphatase 2C; Region: PP2C_2; pfam13672
1055529002680	active site
1055529002681	Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain [General function prediction only]; Region: TerY; COG4245
1055529002682	metal ion-dependent adhesion site (MIDAS); other site
1055529002683	Type IV secretory pathway, VirD2 components (relaxase) [Intracellular trafficking and secretion]; Region: VirD2; COG3843
1055529002684	potential frameshift: common BLAST hit: gi|308185145|ref|YP_003929278.1| integrase/recombinase (xerD)
1055529002685	Fic family protein [Function unknown]; Region: COG3177
1055529002686	Fic/DOC family; Region: Fic; pfam02661
1055529002687	HipA-like C-terminal domain; Region: HipA_C; pfam07804
1055529002688	Type IV secretory pathway, TrbL components [Intracellular trafficking and secretion]; Region: TrbL; COG3846
1055529002689	Protein of unknown function (DUF3991); Region: DUF3991; pfam13154
1055529002690	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1055529002691	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1055529002692	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1055529002693	P-loop; other site
1055529002694	Magnesium ion binding site [ion binding]; other site
1055529002695	Topoisomerase IA [DNA replication, recombination, and repair]; Region: TopA; COG0550
1055529002696	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1055529002697	active site
1055529002698	metal binding site [ion binding]; metal-binding site
1055529002699	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1055529002700	domain I; other site
1055529002701	DNA binding groove [nucleotide binding]
1055529002702	phosphate binding site [ion binding]; other site
1055529002703	domain II; other site
1055529002704	domain III; other site
1055529002705	nucleotide binding site [chemical binding]; other site
1055529002706	catalytic site [active]
1055529002707	domain IV; other site
1055529002708	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1055529002709	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1055529002710	P-loop; other site
1055529002711	Magnesium ion binding site [ion binding]; other site
1055529002712	potential frameshift: common BLAST hit: gi|210134648|ref|YP_002301087.1| relaxase
1055529002713	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041; cl17396
1055529002714	Type IV secretory pathway, VirD4 components [Intracellular trafficking and secretion]; Region: VirD4; COG3505
1055529002715	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1055529002716	Walker A motif; other site
1055529002717	ATP binding site [chemical binding]; other site
1055529002718	Walker B motif; other site
1055529002719	P-type DNA transfer ATPase VirB11; Region: VirB11; TIGR02788
1055529002720	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1055529002721	Walker A motif; other site
1055529002722	ATP binding site [chemical binding]; other site
1055529002723	Walker B motif; other site
1055529002724	Type IV secretory pathway, VirB10 components [Intracellular trafficking and secretion]; Region: VirB10; COG2948
1055529002725	Type IV secretory pathway, VirB9 components [Intracellular trafficking and secretion]; Region: VirB9; COG3504
1055529002726	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911
1055529002727	VirB7 interaction site; other site
1055529002728	VirB8 protein; Region: VirB8; cl01500
1055529002729	potential frameshift: common BLAST hit: gi|188527700|ref|YP_001910387.1| topoisomerase I
1055529002730	Type IV secretory pathway, VirB4 components [Intracellular trafficking and secretion]; Region: VirB4; COG3451
1055529002731	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
1055529002732	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1055529002733	Domain of unknown function DUF87; Region: DUF87; pfam01935
1055529002734	TraM recognition site of TraD and TraG; Region: TraG-D_C; cl17375
1055529002735	Uncharacterized conserved protein [Function unknown]; Region: COG1479
1055529002736	Protein of unknown function DUF262; Region: DUF262; pfam03235
1055529002737	Protein of unknown function DUF262; Region: DUF262; pfam03235
1055529002738	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
1055529002739	Single-stranded DNA-specific exonuclease [DNA replication, recombination, and repair]; Region: RecJ; COG0608
1055529002740	DHH family; Region: DHH; pfam01368
1055529002741	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
1055529002742	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
1055529002743	active site
1055529002744	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1055529002745	catalytic residues [active]
1055529002746	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
1055529002747	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1055529002748	This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1; Region: GT1_UGDG_like; cd03817
1055529002749	putative ADP-binding pocket [chemical binding]; other site
1055529002750	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cd03440
1055529002751	active site 2 [active]
1055529002752	active site 1 [active]
1055529002753	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1055529002754	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1055529002755	S-adenosylmethionine binding site [chemical binding]; other site
1055529002756	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1055529002757	methionyl-tRNA synthetase; Reviewed; Region: PRK12267
1055529002758	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
1055529002759	active site
1055529002760	HIGH motif; other site
1055529002761	KMSKS motif; other site
1055529002762	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1055529002763	anticodon binding site; other site
1055529002764	tRNA binding surface [nucleotide binding]; other site
1055529002765	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
1055529002766	dimer interface [polypeptide binding]; other site
1055529002767	putative tRNA-binding site [nucleotide binding]; other site
1055529002768	Mycolic acid cyclopropane synthetase; Region: CMAS; pfam02353
1055529002769	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1055529002770	S-adenosylmethionine binding site [chemical binding]; other site
1055529002771	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1055529002772	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1055529002773	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
1055529002774	GMP synthase; Reviewed; Region: guaA; PRK00074
1055529002775	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
1055529002776	AMP/PPi binding site [chemical binding]; other site
1055529002777	candidate oxyanion hole; other site
1055529002778	catalytic triad [active]
1055529002779	potential glutamine specificity residues [chemical binding]; other site
1055529002780	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
1055529002781	ATP Binding subdomain [chemical binding]; other site
1055529002782	Ligand Binding sites [chemical binding]; other site
1055529002783	Dimerization subdomain; other site
1055529002784	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
1055529002785	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
1055529002786	molybdopterin cofactor binding site [chemical binding]; other site
1055529002787	substrate binding site [chemical binding]; other site
1055529002788	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
1055529002789	molybdopterin cofactor binding site; other site
1055529002790	Protein of unknown function (DUF3972); Region: DUF3972; pfam13118
1055529002791	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1055529002792	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1055529002793	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1055529002794	catalytic residue [active]
1055529002795	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
1055529002796	nucleotide binding site/active site [active]
1055529002797	HIT family signature motif; other site
1055529002798	catalytic residue [active]
1055529002799	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1055529002800	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1055529002801	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1055529002802	dimer interface [polypeptide binding]; other site
1055529002803	motif 1; other site
1055529002804	active site
1055529002805	motif 2; other site
1055529002806	motif 3; other site
1055529002807	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
1055529002808	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1055529002809	putative tRNA-binding site [nucleotide binding]; other site
1055529002810	tRNA synthetase B5 domain; Region: B5; pfam03484
1055529002811	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
1055529002812	dimer interface [polypeptide binding]; other site
1055529002813	motif 1; other site
1055529002814	motif 3; other site
1055529002815	motif 2; other site
1055529002816	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
1055529002817	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
1055529002818	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
1055529002819	hinge; other site
1055529002820	active site
1055529002821	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
1055529002822	LytB protein; Region: LYTB; pfam02401
1055529002823	ribosomal protein S1; Region: rpsA; TIGR00717
1055529002824	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1055529002825	RNA binding site [nucleotide binding]; other site
1055529002826	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cd00164
1055529002827	RNA binding site [nucleotide binding]; other site
1055529002828	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1055529002829	RNA binding site [nucleotide binding]; other site
1055529002830	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1055529002831	RNA binding site [nucleotide binding]; other site
1055529002832	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cd00164
1055529002833	RNA binding site [nucleotide binding]; other site
1055529002834	D-3-phosphoglycerate dehydrogenase; Region: PGDH; TIGR01327
1055529002835	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_4; cd12173
1055529002836	ligand binding site [chemical binding]; other site
1055529002837	NAD binding site [chemical binding]; other site
1055529002838	dimerization interface [polypeptide binding]; other site
1055529002839	catalytic site [active]
1055529002840	C-terminal ACT (regulatory) domain of D-3-phosphoglycerate dehydrogenase (3PGDH); Region: ACT_3PGDH-xct; cd04902
1055529002841	putative L-serine binding site [chemical binding]; other site
1055529002842	menaquinone biosynthesis decarboxylase, SCO4490 family; Region: mena_SCO4490; TIGR03701
1055529002843	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; cl00311
1055529002844	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
1055529002845	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1055529002846	catalytic residue [active]
1055529002847	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
1055529002848	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1055529002849	putative active site [active]
1055529002850	putative metal binding site [ion binding]; other site
1055529002851	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
1055529002852	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1055529002853	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1055529002854	active site
1055529002855	phosphorylation site [posttranslational modification]
1055529002856	intermolecular recognition site; other site
1055529002857	dimerization interface [polypeptide binding]; other site
1055529002858	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1055529002859	putative binding surface; other site
1055529002860	active site
1055529002861	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
1055529002862	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
1055529002863	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1055529002864	ATP binding site [chemical binding]; other site
1055529002865	Mg2+ binding site [ion binding]; other site
1055529002866	G-X-G motif; other site
1055529002867	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
1055529002868	Response regulator receiver domain; Region: Response_reg; pfam00072
1055529002869	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1055529002870	active site
1055529002871	phosphorylation site [posttranslational modification]
1055529002872	intermolecular recognition site; other site
1055529002873	dimerization interface [polypeptide binding]; other site
1055529002874	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
1055529002875	putative CheA interaction surface; other site
1055529002876	urease subunit alpha; Provisional; Region: PRK13986
1055529002877	Urease gamma-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use...; Region: Urease_gamma; cd00390
1055529002878	alpha-gamma subunit interface [polypeptide binding]; other site
1055529002879	beta-gamma subunit interface [polypeptide binding]; other site
1055529002880	Urease beta-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use of...; Region: Urease_beta; cd00407
1055529002881	alpha-beta subunit interface [polypeptide binding]; other site
1055529002882	urease subunit beta; Provisional; Region: ureB; PRK13985
1055529002883	Urease alpha-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, fungi and plants. Their primary role is to allow the use of...; Region: Urease_alpha; cd00375
1055529002884	subunit interactions [polypeptide binding]; other site
1055529002885	active site
1055529002886	flap region; other site
1055529002887	RloB-like protein; Region: RloB; pfam13707
1055529002888	RloB-like protein; Region: RloB; pfam13707
1055529002889	AAA domain; Region: AAA_21; pfam13304
1055529002890	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
1055529002891	dimer interface [polypeptide binding]; other site
1055529002892	catalytic triad [active]
1055529002893	peroxidatic and resolving cysteines [active]
1055529002894	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
1055529002895	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1055529002896	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1055529002897	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1055529002898	S-adenosylmethionine binding site [chemical binding]; other site
1055529002899	primosome assembly protein PriA; Validated; Region: PRK05580
1055529002900	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1055529002901	ATP binding site [chemical binding]; other site
1055529002902	putative Mg++ binding site [ion binding]; other site
1055529002903	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1055529002904	Sporulation related domain; Region: SPOR; pfam05036
1055529002905	Peptidase family M48; Region: Peptidase_M48; pfam01435
1055529002906	HemK family putative methylases; Region: hemK_fam; TIGR00536
1055529002907	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1055529002908	glutamate dehydrogenase; Provisional; Region: PRK09414
1055529002909	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1055529002910	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
1055529002911	NAD(P) binding site [chemical binding]; other site
1055529002912	Glycosyltransferase family 10 (fucosyltransferase); Region: Glyco_transf_10; pfam00852
1055529002913	ResB protein required for cytochrome c biosynthesis [Posttranslational modification, protein turnover, chaperones]; Region: ResB; cl09125
1055529002914	cytochrome c-type biogenesis protein CcsB; Region: cytochr_II_ccsB; TIGR03144
1055529002915	SoxW family; SoxW is a bacterial periplasmic TRX, containing a redox active CXXC motif, encoded by a genetic locus (sox operon) involved in thiosulfate oxidation. Sulfur bacteria oxidize sulfur compounds to provide reducing equivalents for carbon dioxide...; Region: SoxW; cd02951
1055529002916	catalytic residues [active]
1055529002917	ferrochelatase; Region: hemH; TIGR00109
1055529002918	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
1055529002919	C-terminal domain interface [polypeptide binding]; other site
1055529002920	active site
1055529002921	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
1055529002922	active site
1055529002923	N-terminal domain interface [polypeptide binding]; other site
1055529002924	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
1055529002925	RNA methyltransferase, RsmE family; Region: TIGR00046
1055529002926	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529002927	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1055529002928	trimer interface [polypeptide binding]; other site
1055529002929	active site
1055529002930	acetyl-CoA carboxylase, biotin carboxyl carrier protein; Region: BCCP; TIGR00531
1055529002931	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1055529002932	carboxyltransferase (CT) interaction site; other site
1055529002933	biotinylation site [posttranslational modification]; other site
1055529002934	biotin carboxylase; Validated; Region: PRK08462
1055529002935	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1055529002936	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1055529002937	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1055529002938	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1055529002939	DegT/DnrJ/EryC1/StrS aminotransferase family; Region: DegT_DnrJ_EryC1; pfam01041
1055529002940	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1055529002941	inhibitor-cofactor binding pocket; inhibition site
1055529002942	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1055529002943	catalytic residue [active]
1055529002944	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1055529002945	dimer interface [polypeptide binding]; other site
1055529002946	putative radical transfer pathway; other site
1055529002947	diiron center [ion binding]; other site
1055529002948	tyrosyl radical; other site
1055529002949	protein-L-isoaspartate(D-aspartate) O-methyltransferase; Region: pimt; TIGR00080
1055529002950	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1055529002951	S-adenosylmethionine binding site [chemical binding]; other site
1055529002952	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1055529002953	Predicted permeases [General function prediction only]; Region: COG0795
1055529002954	tRNA pseudouridine(38-40) synthase; Region: hisT_truA; TIGR00071
1055529002955	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1055529002956	dimerization interface 3.5A [polypeptide binding]; other site
1055529002957	active site
1055529002958	UDP-glucose-4-epimerase GalE; Region: galE; TIGR01179
1055529002959	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1055529002960	NAD binding site [chemical binding]; other site
1055529002961	homodimer interface [polypeptide binding]; other site
1055529002962	active site
1055529002963	substrate binding site [chemical binding]; other site
1055529002964	potential protein location (hypothetical protein HPPN135_05590 [Helicobacter pylori Puno135]) that overlaps RNA (tRNA-I)
1055529002965	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
1055529002966	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
1055529002967	putative NAD(P) binding site [chemical binding]; other site
1055529002968	homodimer interface [polypeptide binding]; other site
1055529002969	homotetramer interface [polypeptide binding]; other site
1055529002970	active site
1055529002971	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1055529002972	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1055529002973	binding surface
1055529002974	TPR motif; other site
1055529002975	Sel1-like repeats; Region: SEL1; smart00671
1055529002976	Sel1 repeat; Region: Sel1; cl02723
1055529002977	Sel1-like repeats; Region: SEL1; smart00671
1055529002978	Entner-Doudoroff aldolase; Region: eda; TIGR01182
1055529002979	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1055529002980	active site
1055529002981	intersubunit interface [polypeptide binding]; other site
1055529002982	catalytic residue [active]
1055529002983	phosphogluconate dehydratase; Validated; Region: PRK09054
1055529002984	6-phosphogluconate dehydratase; Region: edd; TIGR01196
1055529002985	Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; Region: Zwf; COG0364
1055529002986	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
1055529002987	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
1055529002988	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1055529002989	6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard...; Region: 6PGL; cd01400
1055529002990	putative active site [active]
1055529002991	glucokinase, proteobacterial type; Region: glk; TIGR00749
1055529002992	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1055529002993	nucleotide binding site [chemical binding]; other site
1055529002994	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1055529002995	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
1055529002996	putative NAD(P) binding site [chemical binding]; other site
1055529002997	putative substrate binding site [chemical binding]; other site
1055529002998	catalytic Zn binding site [ion binding]; other site
1055529002999	structural Zn binding site [ion binding]; other site
1055529003000	dimer interface [polypeptide binding]; other site
1055529003001	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
1055529003002	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1055529003003	active site
1055529003004	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
1055529003005	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1055529003006	active site
1055529003007	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529003008	pyruvate flavodoxin oxidoreductase subunit gamma; Validated; Region: PRK05844
1055529003009	pyruvate/ketoisovalerate ferredoxin oxidoreductase subunit gamma; Provisional; Region: PRK14029
1055529003010	pyruvate flavodoxin oxidoreductase subunit delta; Reviewed; Region: porD; PRK09625
1055529003011	4Fe-4S binding domain; Region: Fer4; pfam00037
1055529003012	pyruvate flavodoxin oxidoreductase subunit alpha; Reviewed; Region: porA; PRK09622
1055529003013	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
1055529003014	dimer interface [polypeptide binding]; other site
1055529003015	PYR/PP interface [polypeptide binding]; other site
1055529003016	TPP binding site [chemical binding]; other site
1055529003017	substrate binding site [chemical binding]; other site
1055529003018	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1055529003019	pyruvate ferredoxin oxidoreductase subunit beta; Provisional; Region: PRK11865
1055529003020	Thiamine pyrophosphate (TPP family), PFOR porB-like subfamily, TPP-binding module; composed of proteins similar to the beta subunit (porB) of the Helicobacter pylori four-subunit pyruvate ferredoxin oxidoreductase (PFOR), which are also found in archaea...; Region: TPP_PFOR_porB_like; cd03376
1055529003021	TPP-binding site [chemical binding]; other site
1055529003022	putative dimer interface [polypeptide binding]; other site
1055529003023	adenylosuccinate lyase; Provisional; Region: PRK08470
1055529003024	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
1055529003025	tetramer interface [polypeptide binding]; other site
1055529003026	active site
1055529003027	Adenylosuccinate lyase C-terminus; Region: ADSL_C; smart00998
1055529003028	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529003029	excinuclease ABC subunit B; Provisional; Region: PRK05298
1055529003030	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1055529003031	ATP binding site [chemical binding]; other site
1055529003032	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1055529003033	putative Mg++ binding site [ion binding]; other site
1055529003034	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1055529003035	nucleotide binding region [chemical binding]; other site
1055529003036	ATP-binding site [chemical binding]; other site
1055529003037	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1055529003038	UvrB/uvrC motif; Region: UVR; pfam02151
1055529003039	Protein of unknown function (DUF3519); Region: DUF3519; pfam12033
1055529003040	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1055529003041	binding surface
1055529003042	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1055529003043	TPR motif; other site
1055529003044	Sel1-like repeats; Region: SEL1; smart00671
1055529003045	Sel1-like repeats; Region: SEL1; smart00671
1055529003046	Sel1-like repeats; Region: SEL1; smart00671
1055529003047	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
1055529003048	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
1055529003049	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08471
1055529003050	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1055529003051	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1055529003052	DNA-methyltransferase (dcm); Region: dcm; TIGR00675
1055529003053	cofactor binding site; other site
1055529003054	DNA binding site [nucleotide binding]
1055529003055	substrate interaction site [chemical binding]; other site
1055529003056	Anti-sigma-28 factor, FlgM; Region: FlgM; cl01052
1055529003057	FKBP-type peptidyl-prolyl cis-trans isomerases 2 [Posttranslational modification, protein turnover, chaperones]; Region: SlpA; COG1047
1055529003058	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1055529003059	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
1055529003060	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1055529003061	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1055529003062	ligand binding site [chemical binding]; other site
1055529003063	translocation protein TolB; Provisional; Region: tolB; PRK04043
1055529003064	TolB amino-terminal domain; Region: TolB_N; pfam04052
1055529003065	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1055529003066	TonB C terminal; Region: TonB_2; pfam13103
1055529003067	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1055529003068	TolR protein; Region: tolR; TIGR02801
1055529003069	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; pfam01618
1055529003070	ATP synthase, F1 epsilon subunit (delta in mitochondria); Region: ATP_synt_epsi; TIGR01216
1055529003071	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
1055529003072	gamma subunit interface [polypeptide binding]; other site
1055529003073	epsilon subunit interface [polypeptide binding]; other site
1055529003074	LBP interface [polypeptide binding]; other site
1055529003075	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
1055529003076	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1055529003077	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1055529003078	alpha subunit interaction interface [polypeptide binding]; other site
1055529003079	Walker A motif; other site
1055529003080	ATP binding site [chemical binding]; other site
1055529003081	Walker B motif; other site
1055529003082	inhibitor binding site; inhibition site
1055529003083	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1055529003084	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1055529003085	core domain interface [polypeptide binding]; other site
1055529003086	delta subunit interface [polypeptide binding]; other site
1055529003087	epsilon subunit interface [polypeptide binding]; other site
1055529003088	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
1055529003089	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1055529003090	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
1055529003091	beta subunit interaction interface [polypeptide binding]; other site
1055529003092	Walker A motif; other site
1055529003093	ATP binding site [chemical binding]; other site
1055529003094	Walker B motif; other site
1055529003095	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1055529003096	F0F1 ATP synthase subunit delta; Provisional; Region: PRK13431
1055529003097	F0F1 ATP synthase subunit B; Validated; Region: PRK08475
1055529003098	F0F1 ATP synthase subunit B'; Validated; Region: PRK08476
1055529003099	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
1055529003100	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
1055529003101	ParB-like nuclease domain; Region: ParB; smart00470
1055529003102	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1055529003103	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1055529003104	P-loop; other site
1055529003105	Magnesium ion binding site [ion binding]; other site
1055529003106	biotin--protein ligase; Provisional; Region: PRK08477
1055529003107	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
1055529003108	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
1055529003109	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
1055529003110	putative active site [active]
1055529003111	substrate binding site [chemical binding]; other site
1055529003112	putative cosubstrate binding site; other site
1055529003113	catalytic site [active]
1055529003114	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1055529003115	substrate binding site [chemical binding]; other site
1055529003116	AAA domain; Region: AAA_13; pfam13166
1055529003117	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4487
1055529003118	Uncharacterized protein conserved in bacteria (DUF2130); Region: DUF2130; pfam09903
1055529003119	Uncharacterized conserved protein [Function unknown]; Region: COG1432
1055529003120	LabA_like proteins; Region: LabA_like/DUF88; cl10034
1055529003121	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1055529003122	tRNA (Guanine-1)-methyltransferase; Region: tRNA_m1G_MT; cl00407
1055529003123	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK14593
1055529003124	RimM N-terminal domain; Region: RimM; pfam01782
1055529003125	PRC-barrel domain; Region: PRC; pfam05239
1055529003126	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
1055529003127	KH domain; Region: KH_4; pfam13083
1055529003128	G-X-X-G motif; other site
1055529003129	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
1055529003130	signal recognition particle protein; Provisional; Region: PRK10867
1055529003131	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
1055529003132	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1055529003133	P loop; other site
1055529003134	GTP binding site [chemical binding]; other site
1055529003135	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1055529003136	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
1055529003137	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1055529003138	active site
1055529003139	HIGH motif; other site
1055529003140	nucleotide binding site [chemical binding]; other site
1055529003141	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1055529003142	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1055529003143	active site
1055529003144	KMSKS motif; other site
1055529003145	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1055529003146	anticodon binding site; other site
1055529003147	flagellar assembly protein FliW; Provisional; Region: PRK13283
1055529003148	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Region: murG; TIGR01133
1055529003149	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1055529003150	active site
1055529003151	homodimer interface [polypeptide binding]; other site
1055529003152	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529003153	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529003154	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
1055529003155	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
1055529003156	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
1055529003157	Fic/DOC family; Region: Fic; cl00960
1055529003158	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cl00184
1055529003159	active site
1055529003160	iron coordination sites [ion binding]; other site
1055529003161	substrate binding pocket [chemical binding]; other site
1055529003162	Uncharacterized conserved protein [Function unknown]; Region: COG4278
1055529003163	metal-binding heat shock protein; Provisional; Region: PRK00016
1055529003164	flavodoxin FldA; Validated; Region: PRK09267
1055529003165	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1055529003166	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1055529003167	Uncharacterized protein, possibly involved in nitrogen fixation [Inorganic ion transport and metabolism]; Region: FixS; COG3197
1055529003168	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
1055529003169	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1055529003170	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1055529003171	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
1055529003172	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
1055529003173	active site
1055529003174	dimer interface [polypeptide binding]; other site
1055529003175	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
1055529003176	dimer interface [polypeptide binding]; other site
1055529003177	active site
1055529003178	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
1055529003179	carbon starvation protein A; Provisional; Region: PRK15015
1055529003180	Carbon starvation protein CstA; Region: CstA; pfam02554
1055529003181	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1055529003182	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1055529003183	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1055529003184	dimer interface [polypeptide binding]; other site
1055529003185	conserved gate region; other site
1055529003186	putative PBP binding loops; other site
1055529003187	ABC-ATPase subunit interface; other site
1055529003188	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1055529003189	dimer interface [polypeptide binding]; other site
1055529003190	conserved gate region; other site
1055529003191	putative PBP binding loops; other site
1055529003192	ABC-ATPase subunit interface; other site
1055529003193	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1055529003194	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1055529003195	Walker A/P-loop; other site
1055529003196	ATP binding site [chemical binding]; other site
1055529003197	Q-loop/lid; other site
1055529003198	ABC transporter signature motif; other site
1055529003199	Walker B; other site
1055529003200	D-loop; other site
1055529003201	H-loop/switch region; other site
1055529003202	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
1055529003203	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1055529003204	substrate binding pocket [chemical binding]; other site
1055529003205	membrane-bound complex binding site; other site
1055529003206	hinge residues; other site
1055529003207	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
1055529003208	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1055529003209	putative substrate translocation pore; other site
1055529003210	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1055529003211	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529003212	purine-nucleoside phosphorylase, family 1 (deoD); Region: deoD; TIGR00107
1055529003213	phosphopentomutase; Provisional; Region: PRK05362
1055529003214	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
1055529003215	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1055529003216	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1055529003217	Nucleoside recognition; Region: Gate; pfam07670
1055529003218	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1055529003219	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1055529003220	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1055529003221	putative substrate translocation pore; other site
1055529003222	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
1055529003223	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
1055529003224	Ligand Binding Site [chemical binding]; other site
1055529003225	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
1055529003226	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
1055529003227	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1055529003228	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
1055529003229	putative arabinose transporter; Provisional; Region: PRK03545
1055529003230	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1055529003231	putative substrate translocation pore; other site
1055529003232	Carbonic anhydrase [Inorganic ion transport and metabolism]; Region: Cah; COG3338
1055529003233	Carbonic anhydrase alpha, prokaryotic-like subfamily. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon...; Region: alpha_CA_prokaryotic_like; cd03124
1055529003234	active site
1055529003235	zinc binding site [ion binding]; other site
1055529003236	aspartate-semialdehyde dehydrogenase (peptidoglycan organisms); Region: asd_B; TIGR01296
1055529003237	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1055529003238	Histidyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: HisS; COG0124
1055529003239	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1055529003240	dimer interface [polypeptide binding]; other site
1055529003241	motif 1; other site
1055529003242	active site
1055529003243	motif 2; other site
1055529003244	motif 3; other site
1055529003245	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1055529003246	anticodon binding site; other site
1055529003247	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1055529003248	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1055529003249	putative active site [active]
1055529003250	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1055529003251	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1055529003252	active site
1055529003253	catalytic tetrad [active]
1055529003254	elongation factor G; Reviewed; Region: PRK00007
1055529003255	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1055529003256	G1 box; other site
1055529003257	putative GEF interaction site [polypeptide binding]; other site
1055529003258	GTP/Mg2+ binding site [chemical binding]; other site
1055529003259	Switch I region; other site
1055529003260	G2 box; other site
1055529003261	G3 box; other site
1055529003262	Switch II region; other site
1055529003263	G4 box; other site
1055529003264	G5 box; other site
1055529003265	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1055529003266	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1055529003267	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1055529003268	30S ribosomal protein S7; Validated; Region: PRK05302
1055529003269	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
1055529003270	S17 interaction site [polypeptide binding]; other site
1055529003271	S8 interaction site; other site
1055529003272	16S rRNA interaction site [nucleotide binding]; other site
1055529003273	streptomycin interaction site [chemical binding]; other site
1055529003274	23S rRNA interaction site [nucleotide binding]; other site
1055529003275	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
1055529003276	bifunctional DNA-directed RNA polymerase subunit beta/beta'; Reviewed; Region: PRK09603
1055529003277	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1055529003278	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
1055529003279	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1055529003280	RPB11 interaction site [polypeptide binding]; other site
1055529003281	RPB12 interaction site [polypeptide binding]; other site
1055529003282	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1055529003283	RPB3 interaction site [polypeptide binding]; other site
1055529003284	RPB1 interaction site [polypeptide binding]; other site
1055529003285	RPB11 interaction site [polypeptide binding]; other site
1055529003286	RPB10 interaction site [polypeptide binding]; other site
1055529003287	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
1055529003288	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
1055529003289	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
1055529003290	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
1055529003291	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1055529003292	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
1055529003293	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1055529003294	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1055529003295	DNA binding site [nucleotide binding]
1055529003296	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1055529003297	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1055529003298	core dimer interface [polypeptide binding]; other site
1055529003299	peripheral dimer interface [polypeptide binding]; other site
1055529003300	L10 interface [polypeptide binding]; other site
1055529003301	L11 interface [polypeptide binding]; other site
1055529003302	putative EF-Tu interaction site [polypeptide binding]; other site
1055529003303	putative EF-G interaction site [polypeptide binding]; other site
1055529003304	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1055529003305	23S rRNA interface [nucleotide binding]; other site
1055529003306	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1055529003307	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1055529003308	mRNA/rRNA interface [nucleotide binding]; other site
1055529003309	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1055529003310	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1055529003311	23S rRNA interface [nucleotide binding]; other site
1055529003312	L7/L12 interface [polypeptide binding]; other site
1055529003313	putative thiostrepton binding site; other site
1055529003314	L25 interface [polypeptide binding]; other site
1055529003315	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1055529003316	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1055529003317	putative homodimer interface [polypeptide binding]; other site
1055529003318	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1055529003319	heterodimer interface [polypeptide binding]; other site
1055529003320	homodimer interface [polypeptide binding]; other site
1055529003321	SecE/Sec61-gamma subunits of protein translocation complex; Region: SecE; cl00481
1055529003322	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
1055529003323	elongation factor Tu; Reviewed; Region: PRK00049
1055529003324	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1055529003325	G1 box; other site
1055529003326	GEF interaction site [polypeptide binding]; other site
1055529003327	GTP/Mg2+ binding site [chemical binding]; other site
1055529003328	Switch I region; other site
1055529003329	G2 box; other site
1055529003330	G3 box; other site
1055529003331	Switch II region; other site
1055529003332	G4 box; other site
1055529003333	G5 box; other site
1055529003334	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1055529003335	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1055529003336	Antibiotic Binding Site [chemical binding]; other site
1055529003337	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1055529003338	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1055529003339	Walker A/P-loop; other site
1055529003340	ATP binding site [chemical binding]; other site
1055529003341	Q-loop/lid; other site
1055529003342	ABC transporter signature motif; other site
1055529003343	Walker B; other site
1055529003344	D-loop; other site
1055529003345	H-loop/switch region; other site
1055529003346	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
1055529003347	HAD-hyrolase-like; Region: Hydrolase_like; pfam13242
1055529003348	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG3392
1055529003349	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; pfam02086
1055529003350	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1055529003351	active site
1055529003352	serine O-acetyltransferase; Region: cysE; TIGR01172
1055529003353	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1055529003354	trimer interface [polypeptide binding]; other site
1055529003355	active site
1055529003356	substrate binding site [chemical binding]; other site
1055529003357	CoA binding site [chemical binding]; other site
1055529003358	F0F1 ATP synthase subunit C; Validated; Region: PRK08482
1055529003359	RNase PH-like 3'-5' exoribonucleases; Region: RNase_PH; cl03114
1055529003360	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
1055529003361	oligomer interface [polypeptide binding]; other site
1055529003362	RNA binding site [nucleotide binding]; other site
1055529003363	RNase PH-like 3'-5' exoribonucleases; Region: RNase_PH; cl03114
1055529003364	oligomer interface [polypeptide binding]; other site
1055529003365	RNA binding site [nucleotide binding]; other site
1055529003366	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
1055529003367	putative nucleic acid binding region [nucleotide binding]; other site
1055529003368	G-X-X-G motif; other site
1055529003369	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
1055529003370	RNA binding site [nucleotide binding]; other site
1055529003371	Predicted phosphoribosyltransferases [General function prediction only]; Region: COG1926
1055529003372	Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452
1055529003373	Organic solvent tolerance protein; Region: OstA_C; pfam04453
1055529003374	Predicted membrane protein/domain [Function unknown]; Region: COG1714
1055529003375	phosphoribosylamine--glycine ligase; Region: purD; TIGR00877
1055529003376	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
1055529003377	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
1055529003378	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
1055529003379	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
1055529003380	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1055529003381	Walker A/P-loop; other site
1055529003382	ATP binding site [chemical binding]; other site
1055529003383	Q-loop/lid; other site
1055529003384	ABC transporter signature motif; other site
1055529003385	Walker B; other site
1055529003386	D-loop; other site
1055529003387	H-loop/switch region; other site
1055529003388	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
1055529003389	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
1055529003390	catalytic residue [active]
1055529003391	putative FPP diphosphate  binding site; other site
1055529003392	putative FPP binding hydrophobic cleft; other site
1055529003393	dimer interface [polypeptide binding]; other site
1055529003394	putative IPP diphosphate binding site; other site
1055529003395	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
1055529003396	FAD binding domain; Region: FAD_binding_4; pfam01565
1055529003397	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1055529003398	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1055529003399	active site residue [active]
1055529003400	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
1055529003401	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1055529003402	active site
1055529003403	camphor resistance protein CrcB; Provisional; Region: PRK14204
1055529003404	coproporphyrinogen III oxidase; Provisional; Region: PRK08446
1055529003405	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1055529003406	FeS/SAM binding site; other site
1055529003407	HemN C-terminal domain; Region: HemN_C; pfam06969
1055529003408	Cytochrome c553 [Energy production and conversion]; Region: COG2863
1055529003409	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
1055529003410	putative active site [active]
1055529003411	Ap4A binding site [chemical binding]; other site
1055529003412	nudix motif; other site
1055529003413	putative metal binding site [ion binding]; other site
1055529003414	aspartate kinase; Reviewed; Region: PRK06635
1055529003415	AAK_AKii-LysC-BS: Amino Acid Kinase Superfamily (AAK), AKii; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis 168, and the lysine plus threonine-sensitive...; Region: AAK_AKii-LysC-BS; cd04261
1055529003416	putative nucleotide binding site [chemical binding]; other site
1055529003417	putative catalytic residues [active]
1055529003418	putative Mg ion binding site [ion binding]; other site
1055529003419	putative aspartate binding site [chemical binding]; other site
1055529003420	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related proteins; Region: ACT_AKii-LysC-BS-like_1; cd04913
1055529003421	putative allosteric regulatory site; other site
1055529003422	ACT domains of the lysine-sensitive, aspartokinase (AK) isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AKii-LysC-BS-like_2; cd04936
1055529003423	putative allosteric regulatory residue; other site
1055529003424	DNA replication regulator; Region: HobA; pfam12163
1055529003425	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1055529003426	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1055529003427	dihydropteroate synthase; Region: DHPS; TIGR01496
1055529003428	substrate binding pocket [chemical binding]; other site
1055529003429	dimer interface [polypeptide binding]; other site
1055529003430	inhibitor binding site; inhibition site
1055529003431	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1055529003432	EamA-like transporter family; Region: EamA; pfam00892
1055529003433	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
1055529003434	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2952
1055529003435	Carbamoylphosphate synthase small subunit [Amino acid transport and metabolism / Nucleotide transport and metabolism]; Region: CarA; COG0505
1055529003436	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; pfam00988
1055529003437	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
1055529003438	catalytic site [active]
1055529003439	subunit interface [polypeptide binding]; other site
1055529003440	formamidase; Provisional; Region: amiF; PRK13287
1055529003441	aliphatic amidases (class 2 nitrilases); Region: aliphatic_amidase; cd07565
1055529003442	multimer interface [polypeptide binding]; other site
1055529003443	active site
1055529003444	catalytic triad [active]
1055529003445	dimer interface [polypeptide binding]; other site
1055529003446	Maf-like protein; Region: Maf; pfam02545
1055529003447	Maf-like protein; Reviewed; Region: PRK04056
1055529003448	putative active site [active]
1055529003449	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1055529003450	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1055529003451	motif 1; other site
1055529003452	active site
1055529003453	motif 2; other site
1055529003454	motif 3; other site
1055529003455	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1055529003456	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2841
1055529003457	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529003458	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1055529003459	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1055529003460	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1055529003461	dimer interface [polypeptide binding]; other site
1055529003462	ssDNA binding site [nucleotide binding]; other site
1055529003463	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1055529003464	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1055529003465	DNA polymerase III subunit delta; Validated; Region: PRK08487
1055529003466	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
1055529003467	Exoribonuclease R [Transcription]; Region: VacB; COG0557
1055529003468	RNB domain; Region: RNB; pfam00773
1055529003469	shikimate 5-dehydrogenase; Region: aroE; TIGR00507
1055529003470	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1055529003471	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1055529003472	shikimate binding site; other site
1055529003473	NAD(P) binding site [chemical binding]; other site
1055529003474	Bacterial SH3 domain; Region: SH3_3; pfam08239
1055529003475	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
1055529003476	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1055529003477	dimer interface [polypeptide binding]; other site
1055529003478	conserved gate region; other site
1055529003479	putative PBP binding loops; other site
1055529003480	ABC-ATPase subunit interface; other site
1055529003481	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1055529003482	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
1055529003483	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1055529003484	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1055529003485	active site
1055529003486	HIGH motif; other site
1055529003487	dimer interface [polypeptide binding]; other site
1055529003488	KMSKS motif; other site
1055529003489	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
1055529003490	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1055529003491	S-adenosylmethionine binding site [chemical binding]; other site
1055529003492	Preprotein translocase subunit SecG [Intracellular trafficking and secretion]; Region: SecG; COG1314
1055529003493	ribosome recycling factor; Reviewed; Region: frr; PRK00083
1055529003494	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1055529003495	hinge region; other site
1055529003496	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1055529003497	active site
1055529003498	RDD family; Region: RDD; pfam06271
1055529003499	NAD-dependent deacetylase; Provisional; Region: PRK00481
1055529003500	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
1055529003501	NAD+ binding site [chemical binding]; other site
1055529003502	substrate binding site [chemical binding]; other site
1055529003503	Zn binding site [ion binding]; other site
1055529003504	NADH dehydrogenase subunit A; Validated; Region: PRK08489
1055529003505	NADH dehydrogenase subunit B; Validated; Region: PRK06411
1055529003506	NADH dehydrogenase subunit C; Provisional; Region: PRK08491
1055529003507	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
1055529003508	NADH dehydrogenase subunit D; Validated; Region: PRK06075
1055529003509	NADH dehydrogenase I, D subunit; Region: NuoD; TIGR01962
1055529003510	NADH dehydrogenase subunit G; Validated; Region: PRK08493
1055529003511	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1055529003512	catalytic loop [active]
1055529003513	iron binding site [ion binding]; other site
1055529003514	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
1055529003515	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1055529003516	molybdopterin cofactor binding site; other site
1055529003517	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
1055529003518	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
1055529003519	NADH-quinone oxidoreductase, chain I; Region: NuoI; TIGR01971
1055529003520	4Fe-4S binding domain; Region: Fer4; cl02805
1055529003521	4Fe-4S binding domain; Region: Fer4; pfam00037
1055529003522	NADH:ubiquinone oxidoreductase subunit 6 (chain J) [Energy production and conversion]; Region: NuoJ; COG0839
1055529003523	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
1055529003524	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
1055529003525	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
1055529003526	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
1055529003527	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1055529003528	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
1055529003529	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1055529003530	proton-translocating NADH-quinone oxidoreductase, chain N; Region: NDH_I_N; TIGR01770
1055529003531	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1055529003532	outer membrane assembly lipoprotein YfiO; Region: OM_YfiO; TIGR03302
1055529003533	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
1055529003534	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
1055529003535	active site
1055529003536	substrate binding site [chemical binding]; other site
1055529003537	metal binding site [ion binding]; metal-binding site
1055529003538	The band 7 domain of flotillin (reggie) like proteins. This group contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual proteins of this...; Region: Band_7; cl02525
1055529003539	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
1055529003540	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
1055529003541	substrate binding site [chemical binding]; other site
1055529003542	active site
1055529003543	catalytic residues [active]
1055529003544	heterodimer interface [polypeptide binding]; other site
1055529003545	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
1055529003546	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
1055529003547	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1055529003548	catalytic residue [active]
1055529003549	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
1055529003550	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
1055529003551	active site
1055529003552	ribulose/triose binding site [chemical binding]; other site
1055529003553	phosphate binding site [ion binding]; other site
1055529003554	substrate (anthranilate) binding pocket [chemical binding]; other site
1055529003555	product (indole) binding pocket [chemical binding]; other site
1055529003556	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
1055529003557	active site
1055529003558	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1055529003559	anthranilate phosphoribosyltransferase; Region: trpD; TIGR01245
1055529003560	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1055529003561	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1055529003562	Glutamine amidotransferase class-I; Region: GATase; pfam00117
1055529003563	glutamine binding [chemical binding]; other site
1055529003564	catalytic triad [active]
1055529003565	anthranilate synthase component I, proteobacterial subset; Region: trpE_proteo; TIGR00565
1055529003566	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1055529003567	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1055529003568	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1055529003569	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1055529003570	putative active site [active]
1055529003571	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1055529003572	active site
1055529003573	motif I; other site
1055529003574	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
1055529003575	motif II; other site
1055529003576	Uncharacterized conserved protein [Function unknown]; Region: COG2353
1055529003577	thiaminase II; Region: salvage_TenA; TIGR04306
1055529003578	Nicotinamide mononucleotide transporter [Coenzyme metabolism]; Region: PnuC; COG3201
1055529003579	Thiamine pyrophosphokinase [Coenzyme metabolism]; Region: THI80; COG1564
1055529003580	Thiamine pyrophosphokinase; Region: TPK; cd07995
1055529003581	active site
1055529003582	dimerization interface [polypeptide binding]; other site
1055529003583	thiamine binding site [chemical binding]; other site
1055529003584	Ribosomal protein L17 [Translation, ribosomal structure and biogenesis]; Region: RplQ; COG0203
1055529003585	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1055529003586	alphaNTD homodimer interface [polypeptide binding]; other site
1055529003587	DNA-directed RNA polymerase, alpha subunit, bacterial and chloroplast-type; Region: rpoA; TIGR02027
1055529003588	alphaNTD - beta interaction site [polypeptide binding]; other site
1055529003589	alphaNTD - beta' interaction site [polypeptide binding]; other site
1055529003590	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1055529003591	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1055529003592	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1055529003593	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1055529003594	RNA binding surface [nucleotide binding]; other site
1055529003595	30S ribosomal protein S11; Validated; Region: PRK05309
1055529003596	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
1055529003597	30S ribosomal protein S13; Region: bact_S13; TIGR03631
1055529003598	Ribosomal protein L36; Region: Ribosomal_L36; cl00380
1055529003599	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1055529003600	rRNA binding site [nucleotide binding]; other site
1055529003601	predicted 30S ribosome binding site; other site
1055529003602	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1055529003603	active site
1055529003604	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1055529003605	SecY translocase; Region: SecY; pfam00344
1055529003606	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1055529003607	ribosomal protein S5, bacterial/organelle type; Region: rpsE_bact; TIGR01021
1055529003608	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1055529003609	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1055529003610	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1055529003611	23S rRNA interface [nucleotide binding]; other site
1055529003612	5S rRNA interface [nucleotide binding]; other site
1055529003613	L27 interface [polypeptide binding]; other site
1055529003614	L5 interface [polypeptide binding]; other site
1055529003615	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1055529003616	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1055529003617	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1055529003618	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08061
1055529003619	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1055529003620	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1055529003621	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1055529003622	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
1055529003623	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1055529003624	RNA binding site [nucleotide binding]; other site
1055529003625	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
1055529003626	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1055529003627	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1055529003628	putative translocon interaction site; other site
1055529003629	23S rRNA interface [nucleotide binding]; other site
1055529003630	signal recognition particle (SRP54) interaction site; other site
1055529003631	L23 interface [polypeptide binding]; other site
1055529003632	trigger factor interaction site; other site
1055529003633	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1055529003634	23S rRNA interface [nucleotide binding]; other site
1055529003635	5S rRNA interface [nucleotide binding]; other site
1055529003636	putative antibiotic binding site [chemical binding]; other site
1055529003637	L25 interface [polypeptide binding]; other site
1055529003638	L27 interface [polypeptide binding]; other site
1055529003639	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1055529003640	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1055529003641	G-X-X-G motif; other site
1055529003642	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1055529003643	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1055529003644	putative translocon binding site; other site
1055529003645	protein-rRNA interface [nucleotide binding]; other site
1055529003646	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
1055529003647	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1055529003648	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1055529003649	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1055529003650	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1055529003651	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1055529003652	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
1055529003653	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1055529003654	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
1055529003655	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1055529003656	Walker A/P-loop; other site
1055529003657	ATP binding site [chemical binding]; other site
1055529003658	Helix-turn-helix domain; Region: HTH_36; pfam13730
1055529003659	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
1055529003660	RNA/DNA hybrid binding site [nucleotide binding]; other site
1055529003661	active site
1055529003662	fumarate hydratase; Reviewed; Region: fumC; PRK00485
1055529003663	Class II fumarases; Region: Fumarase_classII; cd01362
1055529003664	active site
1055529003665	tetramer interface [polypeptide binding]; other site
1055529003666	YtkA-like; Region: YtkA; pfam13115
1055529003667	Outer membrane efflux protein; Region: OEP; pfam02321
1055529003668	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
1055529003669	HlyD family secretion protein; Region: HlyD_3; pfam13437
1055529003670	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
1055529003671	Predicted branched-chain amino acid permeases (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlD; COG1687
1055529003672	AzlC protein; Region: AzlC; cl00570
1055529003673	chaperone protein DnaJ; Provisional; Region: PRK14288
1055529003674	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1055529003675	HSP70 interaction site [polypeptide binding]; other site
1055529003676	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
1055529003677	substrate binding site [polypeptide binding]; other site
1055529003678	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1055529003679	Zn binding sites [ion binding]; other site
1055529003680	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1055529003681	substrate binding site [polypeptide binding]; other site
1055529003682	dimer interface [polypeptide binding]; other site
1055529003683	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
1055529003684	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1055529003685	Ligand Binding Site [chemical binding]; other site
1055529003686	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1055529003687	HSP70 interaction site [polypeptide binding]; other site
1055529003688	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
1055529003689	Cytidylyltransferase; Region: CTP_transf_2; pfam01467
1055529003690	active site
1055529003691	(T/H)XGH motif; other site
1055529003692	nickel responsive regulator; Provisional; Region: PRK00630
1055529003693	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
1055529003694	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
1055529003695	tonB-system energizer ExbB, group 2; Region: exbB2; TIGR02805
1055529003696	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1055529003697	Biopolymer transport protein ExbD/TolR; Region: ExbD; cl00537
1055529003698	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
1055529003699	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1055529003700	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1055529003701	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1055529003702	Mg2+ transporter Helicobacter pylori CorA-like subgroup; Region: HpCorA-like; cd12836
1055529003703	Cl binding site [ion binding]; other site
1055529003704	oligomer interface [polypeptide binding]; other site
1055529003705	phosphoglycerate kinase; Provisional; Region: pgk; PRK00073
1055529003706	Phosphoglycerate kinase; Region: PGK; pfam00162
1055529003707	substrate binding site [chemical binding]; other site
1055529003708	hinge regions; other site
1055529003709	ADP binding site [chemical binding]; other site
1055529003710	catalytic site [active]
1055529003711	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
1055529003712	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
1055529003713	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1055529003714	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
1055529003715	ligand binding site [chemical binding]; other site
1055529003716	active site
1055529003717	UGI interface [polypeptide binding]; other site
1055529003718	catalytic site [active]
1055529003719	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1055529003720	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1055529003721	putative acyl-acceptor binding pocket; other site
1055529003722	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
1055529003723	C-terminal peptidase (prc); Region: prc; TIGR00225
1055529003724	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1055529003725	protein binding site [polypeptide binding]; other site
1055529003726	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1055529003727	Catalytic dyad [active]
1055529003728	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1055529003729	DNA methylase; Region: N6_N4_Mtase; pfam01555
1055529003730	nicotinate-nucleotide pyrophosphorylase; Provisional; Region: PRK05848
1055529003731	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
1055529003732	dimerization interface [polypeptide binding]; other site
1055529003733	active site
1055529003734	Quinolinate synthetase A protein; Region: NadA; cl00420
1055529003735	phosphatidylserine decarboxylase; Provisional; Region: PRK03934
1055529003736	prenyltransferase; Reviewed; Region: ubiA; PRK12874
1055529003737	UbiA prenyltransferase family; Region: UbiA; pfam01040
1055529003738	Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658
1055529003739	Competence protein; Region: Competence; pfam03772
1055529003740	replicative DNA helicase; Provisional; Region: PRK08506
1055529003741	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1055529003742	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1055529003743	Walker A motif; other site
1055529003744	ATP binding site [chemical binding]; other site
1055529003745	Walker B motif; other site
1055529003746	DNA binding loops [nucleotide binding]
1055529003747	yjeF N-terminal region; Region: yjeF_nterm; TIGR00197
1055529003748	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
1055529003749	putative substrate binding site [chemical binding]; other site
1055529003750	putative ATP binding site [chemical binding]; other site
1055529003751	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1055529003752	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
1055529003753	dimer interface [polypeptide binding]; other site
1055529003754	phosphorylation site [posttranslational modification]
1055529003755	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1055529003756	ATP binding site [chemical binding]; other site
1055529003757	Mg2+ binding site [ion binding]; other site
1055529003758	G-X-G motif; other site
1055529003759	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1055529003760	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1055529003761	active site
1055529003762	phosphorylation site [posttranslational modification]
1055529003763	intermolecular recognition site; other site
1055529003764	dimerization interface [polypeptide binding]; other site
1055529003765	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1055529003766	DNA binding site [nucleotide binding]
1055529003767	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1055529003768	DNA methylase; Region: N6_N4_Mtase; pfam01555
1055529003769	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1055529003770	DNA methylase; Region: N6_N4_Mtase; pfam01555
1055529003771	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
1055529003772	DNA methylase; Region: N6_N4_Mtase; pfam01555
1055529003773	DNA methylase; Region: N6_N4_Mtase; pfam01555
1055529003774	Restriction endonuclease EcoRV; Region: Endonuc-EcoRV; pfam09233
1055529003775	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
1055529003776	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
1055529003777	DNA methylase; Region: N6_N4_Mtase; pfam01555
1055529003778	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1055529003779	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1055529003780	ATP binding site [chemical binding]; other site
1055529003781	putative Mg++ binding site [ion binding]; other site
1055529003782	Cell shape-determining protein [Cell envelope biogenesis, outer membrane]; Region: MreC; COG1792
1055529003783	rod shape-determining protein MreC; Region: MreC; pfam04085
1055529003784	rod shape-determining protein MreB; Provisional; Region: PRK13927
1055529003785	MreB and similar proteins; Region: MreB_like; cd10225
1055529003786	nucleotide binding site [chemical binding]; other site
1055529003787	Mg binding site [ion binding]; other site
1055529003788	putative protofilament interaction site [polypeptide binding]; other site
1055529003789	RodZ interaction site [polypeptide binding]; other site
1055529003790	endopeptidase Clp ATP-binding regulatory subunit (clpX); Region: clpX; TIGR00382
1055529003791	ClpX C4-type zinc finger; Region: zf-C4_ClpX; smart00994
1055529003792	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
1055529003793	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1055529003794	Walker A motif; other site
1055529003795	ATP binding site [chemical binding]; other site
1055529003796	Walker B motif; other site
1055529003797	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1055529003798	Acyl-[acyl carrier protein]; Region: LpxA; COG1043
1055529003799	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
1055529003800	active site
1055529003801	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1055529003802	flagellar assembly protein FliW; Provisional; Region: PRK13282
1055529003803	DNA uptake lipoprotein [General function prediction only]; Region: ComL; COG4105
1055529003804	ATP-dependent protease La; Region: lon; TIGR00763
1055529003805	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1055529003806	Walker A motif; other site
1055529003807	ATP binding site [chemical binding]; other site
1055529003808	Walker B motif; other site
1055529003809	arginine finger; other site
1055529003810	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1055529003811	prephenate dehydrogenase; Validated; Region: PRK08507
1055529003812	Prephenate dehydrogenase; Region: PDH; pfam02153
1055529003813	DNA/RNA endonuclease G, NUC1 [Nucleotide transport and metabolism]; Region: NUC1; COG1864
1055529003814	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
1055529003815	active site
1055529003816	substrate binding site [chemical binding]; other site
1055529003817	Mg2+ binding site [ion binding]; other site
1055529003818	Type III restriction/modification enzyme methylation subunit; Region: TypeIII_RM_meth; pfam12564
1055529003819	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
1055529003820	DNA methylase; Region: N6_N4_Mtase; pfam01555
1055529003821	DNA methylase; Region: N6_N4_Mtase; pfam01555
1055529003822	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3421
1055529003823	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1055529003824	ATP binding site [chemical binding]; other site
1055529003825	putative Mg++ binding site [ion binding]; other site
1055529003826	biotin synthase; Provisional; Region: PRK08508
1055529003827	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1055529003828	FeS/SAM binding site; other site
1055529003829	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
1055529003830	YihY family inner membrane protein; Region: yihY_not_rbn; TIGR00765
1055529003831	7-cyano-7-deazaguanine reductase; Region: QueF-II; TIGR03139
1055529003832	Uncharacterized homolog of plant Iojap protein [Function unknown]; Region: COG0799
1055529003833	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1055529003834	tRNA dimethylallyltransferase; Region: miaA; TIGR00174
1055529003835	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
1055529003836	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
1055529003837	Ligand binding site; other site
1055529003838	metal-binding site
1055529003839	Adenine-specific methyltransferase EcoRI; Region: EcoRI_methylase; pfam13651
1055529003840	Restriction endonuclease EcoRI; Region: EcoRI; pfam02963
1055529003841	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13904
1055529003842	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1055529003843	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
1055529003844	flagellum-specific ATP synthase; Validated; Region: fliI; PRK08472
1055529003845	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
1055529003846	Walker A motif/ATP binding site; other site
1055529003847	Walker B motif; other site
1055529003848	Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis [Cell motility and secretion / Intracellular trafficking and secretion]; Region: VirB11; COG0630
1055529003849	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
1055529003850	ATP binding site [chemical binding]; other site
1055529003851	Walker A motif; other site
1055529003852	hexamer interface [polypeptide binding]; other site
1055529003853	Walker B motif; other site
1055529003854	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
1055529003855	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1055529003856	active site
1055529003857	HIGH motif; other site
1055529003858	nucleotide binding site [chemical binding]; other site
1055529003859	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1055529003860	active site
1055529003861	KMSKS motif; other site
1055529003862	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
1055529003863	tRNA binding surface [nucleotide binding]; other site
1055529003864	anticodon binding site; other site
1055529003865	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1055529003866	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1055529003867	RNA binding surface [nucleotide binding]; other site
1055529003868	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14462
1055529003869	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1055529003870	FeS/SAM binding site; other site
1055529003871	KpsF/GutQ family protein; Region: kpsF; TIGR00393
1055529003872	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1055529003873	putative active site [active]
1055529003874	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1055529003875	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
1055529003876	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1055529003877	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
1055529003878	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1055529003879	dimethyladenosine transferase; Region: ksgA; TIGR00755
1055529003880	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1055529003881	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1055529003882	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1055529003883	formyltetrahydrofolate deformylase; Region: PurU; TIGR00655
1055529003884	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
1055529003885	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
1055529003886	putative active site [active]
1055529003887	putative substrate binding site [chemical binding]; other site
1055529003888	putative cosubstrate binding site; other site
1055529003889	catalytic site [active]
1055529003890	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
1055529003891	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1055529003892	tandem repeat interface [polypeptide binding]; other site
1055529003893	oligomer interface [polypeptide binding]; other site
1055529003894	active site residues [active]
1055529003895	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
1055529003896	active site
1055529003897	carbon storage regulator; Provisional; Region: PRK00568
1055529003898	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: PRK04181
1055529003899	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1055529003900	SmpB-tmRNA interface; other site
1055529003901	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; pfam01618
1055529003902	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1055529003903	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
1055529003904	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
1055529003905	ribonuclease P protein component, eubacterial; Region: rnpA; TIGR00188
1055529003906	hypothetical protein; Provisional; Region: PRK14374
1055529003907	membrane protein insertase; Provisional; Region: PRK01318
1055529003908	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
1055529003909	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
1055529003910	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1055529003911	tRNA modification GTPase TrmE; Region: mnmE_trmE_thdF; TIGR00450
1055529003912	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1055529003913	G1 box; other site
1055529003914	GTP/Mg2+ binding site [chemical binding]; other site
1055529003915	Switch I region; other site
1055529003916	G2 box; other site
1055529003917	Switch II region; other site
1055529003918	G3 box; other site
1055529003919	G4 box; other site
1055529003920	G5 box; other site
1055529003921	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
1055529003922	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529003923	LPP20 lipoprotein; Region: LPP20; pfam02169
1055529003924	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
1055529003925	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1055529003926	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1055529003927	catalytic residues [active]
1055529003928	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
1055529003929	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1055529003930	RNA binding surface [nucleotide binding]; other site
1055529003931	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
1055529003932	active site
1055529003933	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113
1055529003934	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
1055529003935	active site
1055529003936	PHP Thumb interface [polypeptide binding]; other site
1055529003937	metal binding site [ion binding]; metal-binding site
1055529003938	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1055529003939	generic binding surface I; other site
1055529003940	generic binding surface II; other site
1055529003941	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
1055529003942	Heat shock protein [Posttranslational modification, protein turnover, chaperones]; Region: HslJ; COG3187
1055529003943	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
1055529003944	mce related protein; Region: MCE; pfam02470
1055529003945	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
1055529003946	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
1055529003947	Walker A/P-loop; other site
1055529003948	ATP binding site [chemical binding]; other site
1055529003949	Q-loop/lid; other site
1055529003950	ABC transporter signature motif; other site
1055529003951	Walker B; other site
1055529003952	D-loop; other site
1055529003953	H-loop/switch region; other site
1055529003954	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
1055529003955	conserved hypothetical integral membrane protein; Region: TIGR00056
1055529003956	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529003957	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
1055529003958	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
1055529003959	homodimer interface [polypeptide binding]; other site
1055529003960	substrate-cofactor binding pocket; other site
1055529003961	catalytic residue [active]
1055529003962	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529003963	DNA polymerase I; Region: pola; TIGR00593
1055529003964	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1055529003965	active site
1055529003966	metal binding site 1 [ion binding]; metal-binding site
1055529003967	putative 5' ssDNA interaction site; other site
1055529003968	metal binding site 3; metal-binding site
1055529003969	metal binding site 2 [ion binding]; metal-binding site
1055529003970	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1055529003971	putative DNA binding site [nucleotide binding]; other site
1055529003972	putative metal binding site [ion binding]; other site
1055529003973	3'-5' exonuclease; Region: 35EXOc; smart00474
1055529003974	active site
1055529003975	substrate binding site [chemical binding]; other site
1055529003976	catalytic site [active]
1055529003977	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
1055529003978	active site
1055529003979	DNA binding site [nucleotide binding]
1055529003980	catalytic site [active]
1055529003981	potential frameshift: common BLAST hit: gi|208435339|ref|YP_002267005.1| type II restriction enzyme
1055529003982	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1055529003983	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1055529003984	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
1055529003985	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
1055529003986	thymidylate kinase; Validated; Region: tmk; PRK00698
1055529003987	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1055529003988	TMP-binding site; other site
1055529003989	ATP-binding site [chemical binding]; other site
1055529003990	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
1055529003991	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
1055529003992	active site
1055529003993	(T/H)XGH motif; other site
1055529003994	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
1055529003995	Flavoprotein; Region: Flavoprotein; pfam02441
1055529003996	flagellar basal body P-ring biosynthesis protein FlgA; Reviewed; Region: flgA; PRK08515
1055529003997	flagella basal body P-ring formation protein FlgA; Region: flgA_cterm; TIGR03170
1055529003998	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
1055529003999	Part of AAA domain; Region: AAA_19; pfam13245
1055529004000	Family description; Region: UvrD_C_2; pfam13538
1055529004001	TPR repeat; Region: TPR_11; pfam13414
1055529004002	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1055529004003	TPR motif; other site
1055529004004	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1055529004005	binding surface
1055529004006	TPR motif; other site
1055529004007	seryl-tRNA synthetase; Provisional; Region: PRK05431
1055529004008	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1055529004009	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1055529004010	dimer interface [polypeptide binding]; other site
1055529004011	active site
1055529004012	motif 1; other site
1055529004013	motif 2; other site
1055529004014	motif 3; other site
1055529004015	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1055529004016	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cd07197
1055529004017	active site
1055529004018	catalytic triad [active]
1055529004019	dimer interface [polypeptide binding]; other site
1055529004020	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK14065
1055529004021	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
1055529004022	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1055529004023	S-adenosylmethionine binding site [chemical binding]; other site
1055529004024	Uncharacterized protein family (UPF0093); Region: UPF0093; cl00863
1055529004025	uncharacterized protein, YigZ family; Region: IMPACT_YIGZ; TIGR00257
1055529004026	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
1055529004027	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
1055529004028	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1055529004029	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
1055529004030	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1055529004031	HlyD family secretion protein; Region: HlyD_3; pfam13437
1055529004032	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
1055529004033	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1055529004034	Domain of unknown function DUF21; Region: DUF21; pfam01595
1055529004035	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1055529004036	Transporter associated domain; Region: CorC_HlyC; smart01091
1055529004037	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1055529004038	Phosphate transporter family; Region: PHO4; pfam01384
1055529004039	NifU-like domain; Region: NifU; pfam01106
1055529004040	UDP-N-acetylmuramyl-tripeptide synthetase; Region: murE; TIGR01085
1055529004041	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1055529004042	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1055529004043	Transaldolase-like proteins from plants and bacteria; Region: Transaldolase_like; cd00955
1055529004044	putative active site [active]
1055529004045	transaldolase; Provisional; Region: PRK03903
1055529004046	catalytic residue [active]
1055529004047	ribosomal protein L25, Ctc-form; Region: ctc_TL5; TIGR00731
1055529004048	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1055529004049	5S rRNA interface [nucleotide binding]; other site
1055529004050	CTC domain interface [polypeptide binding]; other site
1055529004051	L16 interface [polypeptide binding]; other site
1055529004052	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1055529004053	putative active site [active]
1055529004054	catalytic residue [active]
1055529004055	Predicted permeases [General function prediction only]; Region: COG0795
1055529004056	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1055529004057	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529004058	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3399
1055529004059	Putative metal-binding domain of cation transport ATPase; Region: ATPase-cat_bd; pfam12156
1055529004060	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
1055529004061	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1055529004062	metal-binding site [ion binding]
1055529004063	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1055529004064	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1055529004065	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
1055529004066	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1055529004067	S-adenosylmethionine binding site [chemical binding]; other site
1055529004068	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
1055529004069	catalytic motif [active]
1055529004070	Zn binding site [ion binding]; other site
1055529004071	Pyrimidine reductase, riboflavin biosynthesis [Coenzyme metabolism]; Region: RibD; COG1985
1055529004072	RibD C-terminal domain; Region: RibD_C; cl17279
1055529004073	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
1055529004074	Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism]; Region: LYS9; COG1748
1055529004075	NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226
1055529004076	NAD(P) binding pocket [chemical binding]; other site
1055529004077	cytochrome c oxidase accessory protein FixG; Region: ccoG_rdxA_fixG; TIGR02745
1055529004078	4Fe-4S binding domain; Region: Fer4_5; pfam12801
1055529004079	Ubp3 associated protein Bre5; Region: Bre5; pfam11614
1055529004080	acyl-phosphate glycerol 3-phosphate acyltransferase; Region: TIGR00023
1055529004081	FolB domain; Region: folB_dom; TIGR00526
1055529004082	active site
1055529004083	TonB-dependent Receptor Plug Domain; Region: Plug; cl08461
1055529004084	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
1055529004085	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1055529004086	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1055529004087	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
1055529004088	L-seryl-tRNA selenium transferase; Region: SelA; pfam03841
1055529004089	transcription elongation factor NusA; Provisional; Region: nusA; PRK12328
1055529004090	NusA N-terminal domain; Region: NusA_N; pfam08529
1055529004091	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
1055529004092	RNA binding site [nucleotide binding]; other site
1055529004093	homodimer interface [polypeptide binding]; other site
1055529004094	NusA-like KH domain; Region: KH_5; pfam13184
1055529004095	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1055529004096	G-X-X-G motif; other site
1055529004097	Type II restriction enzyme, methylase subunits [Defense mechanisms]; Region: COG1002
1055529004098	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
1055529004099	potential frameshift: common BLAST hit: gi|188528290|ref|YP_001910977.1| type III restriction enzyme
1055529004100	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
1055529004101	ATP-dependent DNA helicase RecG; Region: recG; TIGR00643
1055529004102	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
1055529004103	ssDNA binding site; other site
1055529004104	generic binding surface II; other site
1055529004105	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1055529004106	ATP binding site [chemical binding]; other site
1055529004107	putative Mg++ binding site [ion binding]; other site
1055529004108	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1055529004109	nucleotide binding region [chemical binding]; other site
1055529004110	ATP-binding site [chemical binding]; other site
1055529004111	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529004112	Human Ape1-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Ape1-like_AP-endo; cd09087
1055529004113	active site
1055529004114	putative catalytic site [active]
1055529004115	DNA binding site [nucleotide binding]
1055529004116	putative phosphate binding site [ion binding]; other site
1055529004117	metal binding site A [ion binding]; metal-binding site
1055529004118	AP binding site [nucleotide binding]; other site
1055529004119	metal binding site B [ion binding]; metal-binding site
1055529004120	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
1055529004121	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1055529004122	Walker A motif; other site
1055529004123	ATP binding site [chemical binding]; other site
1055529004124	Walker B motif; other site
1055529004125	arginine finger; other site
1055529004126	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1055529004127	DnaA box-binding interface [nucleotide binding]; other site
1055529004128	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
1055529004129	Protein of unknown function (DUF2443); Region: DUF2443; pfam10398
1055529004130	glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Region: glmS; TIGR01135
1055529004131	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
1055529004132	glutaminase active site [active]
1055529004133	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1055529004134	dimer interface [polypeptide binding]; other site
1055529004135	active site
1055529004136	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1055529004137	dimer interface [polypeptide binding]; other site
1055529004138	active site
1055529004139	FAD-dependent thymidylate synthase; Reviewed; Region: thyX; PRK00847
1055529004140	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1055529004141	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1055529004142	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1055529004143	Abi-like protein; Region: Abi_2; cl01988
1055529004144	HsdM N-terminal domain; Region: HsdM_N; pfam12161
1055529004145	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
1055529004146	type I site-specific deoxyribonuclease, HsdR family; Region: hsdR; TIGR00348
1055529004147	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
1055529004148	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1055529004149	ATP binding site [chemical binding]; other site
1055529004150	putative Mg++ binding site [ion binding]; other site
1055529004151	Protein of unknown function DUF45; Region: DUF45; pfam01863
1055529004152	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
1055529004153	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1055529004154	N-terminal plug; other site
1055529004155	ligand-binding site [chemical binding]; other site
1055529004156	Arginase family; Region: Arginase; cd09989
1055529004157	active site
1055529004158	Mn binding site [ion binding]; other site
1055529004159	oligomer interface [polypeptide binding]; other site
1055529004160	S-methylmethionine transporter; Provisional; Region: PRK11387
1055529004161	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
1055529004162	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
1055529004163	hexamer interface [polypeptide binding]; other site
1055529004164	ligand binding site [chemical binding]; other site
1055529004165	putative active site [active]
1055529004166	NAD(P) binding site [chemical binding]; other site
1055529004167	Uncharacterized conserved protein [Function unknown]; Region: COG1479
1055529004168	Protein of unknown function DUF262; Region: DUF262; pfam03235
1055529004169	Protein of unknown function DUF262; Region: DUF262; pfam03235
1055529004170	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
1055529004171	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055529004172	NAD kinase [Coenzyme metabolism]; Region: nadF; COG0061
1055529004173	ATP-NAD kinase; Region: NAD_kinase; pfam01513
1055529004174	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
1055529004175	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1055529004176	Walker A/P-loop; other site
1055529004177	ATP binding site [chemical binding]; other site
1055529004178	Q-loop/lid; other site
1055529004179	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1055529004180	ABC transporter signature motif; other site
1055529004181	Walker B; other site
1055529004182	D-loop; other site
1055529004183	H-loop/switch region; other site
1055529004184	Domain of unknown function (DUF814); Region: DUF814; pfam05670
1055529004185	DNA polymerase III subunit epsilon; Provisional; Region: PRK08517
1055529004186	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1055529004187	active site
1055529004188	catalytic site [active]
1055529004189	substrate binding site [chemical binding]; other site
1055529004190	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1055529004191	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
1055529004192	substrate binding site [chemical binding]; other site
1055529004193	hexamer interface [polypeptide binding]; other site
1055529004194	metal binding site [ion binding]; metal-binding site
1055529004195	FIG, FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with various substrates. Fructose-1,6-bisphospatase (both the major and the glpX-encoded variant) hydrolyze fructose-1,6,-bisphosphate to fructose-6-phosphate in...; Region: FIG; cl00289
1055529004196	active site
1055529004197	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1055529004198	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
1055529004199	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1055529004200	cofactor binding site; other site
1055529004201	DNA binding site [nucleotide binding]
1055529004202	substrate interaction site [chemical binding]; other site
1055529004203	elongation factor Ts; Provisional; Region: tsf; PRK09377
1055529004204	UBA/TS-N domain; Region: UBA; pfam00627
1055529004205	Elongation factor TS; Region: EF_TS; pfam00889
1055529004206	Elongation factor TS; Region: EF_TS; pfam00889
1055529004207	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1055529004208	rRNA interaction site [nucleotide binding]; other site
1055529004209	S8 interaction site; other site
1055529004210	putative laminin-1 binding site; other site
1055529004211	putative recombination protein RecB; Provisional; Region: PRK13909
1055529004212	Family description; Region: UvrD_C_2; pfam13538
1055529004213	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cl00641
1055529004214	pH-dependent sodium/proton antiporter; Provisional; Region: nhaA; PRK14856
1055529004215	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
1055529004216	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
1055529004217	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
1055529004218	protein-export membrane protein SecF; Region: 3a0501s07; TIGR00966
1055529004219	Protein export membrane protein; Region: SecD_SecF; pfam02355
1055529004220	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
1055529004221	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1055529004222	HIGH motif; other site
1055529004223	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1055529004224	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1055529004225	active site
1055529004226	KMSKS motif; other site
1055529004227	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1055529004228	tRNA binding surface [nucleotide binding]; other site
1055529004229	anticodon binding site; other site
1055529004230	Lipopolysaccharide-assembly; Region: LptE; pfam04390
1055529004231	folylpolyglutamate synthase/dihydrofolate synthase; Region: folC; TIGR01499
1055529004232	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1055529004233	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1055529004234	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1055529004235	Peptidase family M23; Region: Peptidase_M23; pfam01551
1055529004236	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1055529004237	Peptidase family M23; Region: Peptidase_M23; pfam01551
1055529004238	Integral membrane protein CcmA involved in cell shape determination [Cell envelope biogenesis, outer membrane]; Region: CcmA; COG1664
1055529004239	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
1055529004240	transcription-repair coupling factor (mfd); Region: mfd; TIGR00580
1055529004241	CarD-like/TRCF domain; Region: CarD_CdnL_TRCF; pfam02559
1055529004242	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1055529004243	ATP binding site [chemical binding]; other site
1055529004244	putative Mg++ binding site [ion binding]; other site
1055529004245	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1055529004246	nucleotide binding region [chemical binding]; other site
1055529004247	ATP-binding site [chemical binding]; other site
1055529004248	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
1055529004249	ubiquinol-cytochrome c reductase, iron-sulfur subunit; Region: Rieske_proteo; TIGR01416
1055529004250	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
1055529004251	iron-sulfur cluster [ion binding]; other site
1055529004252	[2Fe-2S] cluster binding site [ion binding]; other site
1055529004253	Cytochrome b subunit of the bc complex [Energy production and conversion]; Region: QcrB; COG1290
1055529004254	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cd00284
1055529004255	intrachain domain interface; other site
1055529004256	interchain domain interface [polypeptide binding]; other site
1055529004257	heme bH binding site [chemical binding]; other site
1055529004258	Qi binding site; other site
1055529004259	heme bL binding site [chemical binding]; other site
1055529004260	Qo binding site; other site
1055529004261	interchain domain interface [polypeptide binding]; other site
1055529004262	intrachain domain interface; other site
1055529004263	Qi binding site; other site
1055529004264	Cytochrome b(C-terminal)/b6/petD; Region: Cytochrom_B_C; pfam00032
1055529004265	Qo binding site; other site
1055529004266	Cytochrome c1 [Energy production and conversion]; Region: CYT1; COG2857
1055529004267	Cytochrome c; Region: Cytochrom_C; pfam00034
1055529004268	Cytochrome c; Region: Cytochrom_C; cl11414
1055529004269	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1055529004270	active site
1055529004271	metal binding site [ion binding]; metal-binding site
1055529004272	Predicted ATPases [General function prediction only]; Region: COG1106
1055529004273	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1055529004274	Walker A/P-loop; other site
1055529004275	ATP binding site [chemical binding]; other site
1055529004276	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
1055529004277	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1055529004278	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1055529004279	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK03907
1055529004280	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
1055529004281	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1055529004282	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
1055529004283	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
1055529004284	Cell cycle protein; Region: FTSW_RODA_SPOVE; pfam01098
1055529004285	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1055529004286	Periplasmic binding protein TroA_d.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_d; cd01141
1055529004287	putative ligand binding site [chemical binding]; other site
1055529004288	Periplasmic binding protein TroA_d.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_d; cd01141
1055529004289	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1055529004290	putative ligand binding site [chemical binding]; other site
1055529004291	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1055529004292	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1055529004293	dimer interface [polypeptide binding]; other site
1055529004294	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1055529004295	catalytic triad [active]
1055529004296	peroxidatic and resolving cysteines [active]
1055529004297	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1055529004298	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1055529004299	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
1055529004300	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1055529004301	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1055529004302	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
1055529004303	G1 box; other site
1055529004304	GTP/Mg2+ binding site [chemical binding]; other site
1055529004305	Switch I region; other site
1055529004306	G2 box; other site
1055529004307	G3 box; other site
1055529004308	Switch II region; other site
1055529004309	G4 box; other site
1055529004310	G5 box; other site
1055529004311	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1934
1055529004312	OstA-like protein; Region: OstA; pfam03968
1055529004313	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1055529004314	motif II; other site
1055529004315	Lipoproteins [Cell envelope biogenesis, outer membrane]; Region: RlpA; COG0797
1055529004316	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
1055529004317	Sporulation related domain; Region: SPOR; pfam05036
1055529004318	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1055529004319	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1055529004320	catalytic residue [active]
1055529004321	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1055529004322	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
1055529004323	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1055529004324	active site
1055529004325	riboflavin synthase, alpha subunit; Region: ribE; TIGR00187
1055529004326	Lumazine binding domain; Region: Lum_binding; pfam00677
1055529004327	Lumazine binding domain; Region: Lum_binding; pfam00677
1055529004328	flhB C-terminus-related protein; Region: flhB_rel; TIGR00789
1055529004329	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
1055529004330	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1055529004331	Walker A/P-loop; other site
1055529004332	ATP binding site [chemical binding]; other site
1055529004333	Q-loop/lid; other site
1055529004334	ABC transporter signature motif; other site
1055529004335	Walker B; other site
1055529004336	D-loop; other site
1055529004337	H-loop/switch region; other site
1055529004338	NIL domain; Region: NIL; pfam09383
1055529004339	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
1055529004340	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1055529004341	PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_5; cd03394
1055529004342	active site
1055529004343	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
1055529004344	This subfamily is composed of uncharacterized bacterial glycosyltransferases in the MraY-like family. This family contains both eukaryotic and prokaryotic UDP-D-N-acetylhexosamine:polyprenol phosphate D-N-acetylhexosamine-1-phosphate transferases, which...; Region: GT_MraY_like; cd06912
1055529004345	Mg++ binding site [ion binding]; other site
1055529004346	putative catalytic motif [active]
1055529004347	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
1055529004348	active site
1055529004349	hydrophilic channel; other site
1055529004350	dimerization interface [polypeptide binding]; other site
1055529004351	catalytic residues [active]
1055529004352	active site lid [active]
1055529004353	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
1055529004354	4-hydroxythreonine-4-phosphate dehydrogenase; Provisional; Region: pdxA; PRK03946
1055529004355	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
1055529004356	metallohydrolase, glycoprotease/Kae1 family; Region: gcp_kae1; TIGR00329
1055529004357	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
1055529004358	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1055529004359	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1055529004360	hypothetical protein; Provisional; Region: PRK10236
1055529004361	Domain of unknown function (DUF3944); Region: DUF3944; pfam13099
1055529004362	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735