-- dump date   	20140619_120912
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1006551000001	protein disaggregation chaperone; Provisional; Region: PRK10865
1006551000002	Clp amino terminal domain; Region: Clp_N; pfam02861
1006551000003	Clp amino terminal domain; Region: Clp_N; pfam02861
1006551000004	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1006551000005	Walker A motif; other site
1006551000006	ATP binding site [chemical binding]; other site
1006551000007	Walker B motif; other site
1006551000008	arginine finger; other site
1006551000009	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1006551000010	Walker A motif; other site
1006551000011	ATP binding site [chemical binding]; other site
1006551000012	Walker B motif; other site
1006551000013	arginine finger; other site
1006551000014	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1006551000015	hypothetical protein; Provisional; Region: PRK10723
1006551000016	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
1006551000017	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
1006551000018	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1006551000019	RNA binding surface [nucleotide binding]; other site
1006551000020	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1006551000021	active site
1006551000022	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
1006551000023	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1006551000024	30S subunit binding site; other site
1006551000025	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
1006551000026	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
1006551000027	Prephenate dehydratase; Region: PDT; pfam00800
1006551000028	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
1006551000029	putative L-Phe binding site [chemical binding]; other site
1006551000030	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
1006551000031	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
1006551000032	Chorismate mutase type II; Region: CM_2; cl00693
1006551000033	prephenate dehydrogenase; Validated; Region: PRK08507
1006551000034	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
1006551000035	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1006551000036	putative inner membrane diguanylate cyclase; Provisional; Region: PRK09966
1006551000037	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1006551000038	metal binding site [ion binding]; metal-binding site
1006551000039	active site
1006551000040	I-site; other site
1006551000041	putative outer membrane lipoprotein; Provisional; Region: PRK09967
1006551000042	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1006551000043	ligand binding site [chemical binding]; other site
1006551000044	Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182
1006551000045	PepSY-associated TM helix; Region: PepSY_TM_1; pfam13172
1006551000046	PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703
1006551000047	Protein of unknown function (DUF2946); Region: DUF2946; pfam11162
1006551000048	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1006551000049	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
1006551000050	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
1006551000051	RimM N-terminal domain; Region: RimM; pfam01782
1006551000052	PRC-barrel domain; Region: PRC; pfam05239
1006551000053	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
1006551000054	signal recognition particle protein; Provisional; Region: PRK10867
1006551000055	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
1006551000056	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1006551000057	P loop; other site
1006551000058	GTP binding site [chemical binding]; other site
1006551000059	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1006551000060	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
1006551000061	hypothetical protein; Provisional; Region: PRK11573
1006551000062	Domain of unknown function DUF21; Region: DUF21; pfam01595
1006551000063	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1006551000064	Transporter associated domain; Region: CorC_HlyC; smart01091
1006551000065	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
1006551000066	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1006551000067	dimer interface [polypeptide binding]; other site
1006551000068	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1006551000069	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
1006551000070	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
1006551000071	recombination and repair protein; Provisional; Region: PRK10869
1006551000072	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1006551000073	Walker A/P-loop; other site
1006551000074	ATP binding site [chemical binding]; other site
1006551000075	Q-loop/lid; other site
1006551000076	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1006551000077	ABC transporter signature motif; other site
1006551000078	Walker B; other site
1006551000079	D-loop; other site
1006551000080	H-loop/switch region; other site
1006551000081	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
1006551000082	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
1006551000083	hypothetical protein; Validated; Region: PRK01777
1006551000084	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
1006551000085	putative coenzyme Q binding site [chemical binding]; other site
1006551000086	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1006551000087	SmpB-tmRNA interface; other site
1006551000088	integrase; Provisional; Region: PRK09692
1006551000089	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1006551000090	active site
1006551000091	Int/Topo IB signature motif; other site
1006551000092	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
1006551000093	AAA domain; Region: AAA_12; pfam13087
1006551000094	Lhr-like helicases [General function prediction only]; Region: Lhr; COG1201
1006551000095	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1006551000096	ATP binding site [chemical binding]; other site
1006551000097	putative Mg++ binding site [ion binding]; other site
1006551000098	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1006551000099	nucleotide binding region [chemical binding]; other site
1006551000100	ATP-binding site [chemical binding]; other site
1006551000101	P-loop Domain of unknown function (DUF2791); Region: DUF2791; pfam10923
1006551000102	AAA ATPase domain; Region: AAA_16; pfam13191
1006551000103	Domain of unknown function (DUF4016); Region: DUF4016; pfam13208
1006551000104	tellurite resistance protein terB; Region: terB; cd07176
1006551000105	putative metal binding site [ion binding]; other site
1006551000106	Plant protein of unknown function (DUF869); Region: DUF869; pfam05911
1006551000107	Domain of unknown function (DUF4157); Region: DUF4157; pfam13699
1006551000108	Phi-29 DNA terminal protein GP3; Region: Phi-29_GP3; cl17520
1006551000109	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
1006551000110	type VI secretion-associated protein, VC_A0119 family; Region: VI_chp_7; TIGR03362
1006551000111	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551000112	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551000113	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1006551000114	dimerization interface [polypeptide binding]; other site
1006551000115	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
1006551000116	agmatinase; Region: agmatinase; TIGR01230
1006551000117	oligomer interface [polypeptide binding]; other site
1006551000118	putative active site [active]
1006551000119	Mn binding site [ion binding]; other site
1006551000120	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
1006551000121	oxidase reductase; Provisional; Region: PTZ00273
1006551000122	non-haem dioxygenase in morphine synthesis N-terminal; Region: DIOX_N; pfam14226
1006551000123	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy; pfam03171
1006551000124	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551000125	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1006551000126	substrate binding pocket [chemical binding]; other site
1006551000127	membrane-bound complex binding site; other site
1006551000128	hinge residues; other site
1006551000129	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551000130	dimer interface [polypeptide binding]; other site
1006551000131	conserved gate region; other site
1006551000132	putative PBP binding loops; other site
1006551000133	ABC-ATPase subunit interface; other site
1006551000134	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1006551000135	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1006551000136	Walker A/P-loop; other site
1006551000137	ATP binding site [chemical binding]; other site
1006551000138	Q-loop/lid; other site
1006551000139	ABC transporter signature motif; other site
1006551000140	Walker B; other site
1006551000141	D-loop; other site
1006551000142	H-loop/switch region; other site
1006551000143	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cl00214
1006551000144	intersubunit interface [polypeptide binding]; other site
1006551000145	active site
1006551000146	Zn2+ binding site [ion binding]; other site
1006551000147	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164
1006551000148	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; Region: 2-Hacid_dh; pfam00389
1006551000149	putative ligand binding site [chemical binding]; other site
1006551000150	NAD binding site [chemical binding]; other site
1006551000151	dimerization interface [polypeptide binding]; other site
1006551000152	catalytic site [active]
1006551000153	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
1006551000154	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: COG4235
1006551000155	thiol:disulfide interchange protein DsbE; Provisional; Region: PRK15412
1006551000156	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
1006551000157	catalytic residues [active]
1006551000158	central insert; other site
1006551000159	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
1006551000160	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13165
1006551000161	Heme exporter protein D (CcmD); Region: CcmD; cl11475
1006551000162	heme exporter protein CcmC; Region: ccmC; TIGR01191
1006551000163	heme exporter protein CcmB; Region: ccmB; TIGR01190
1006551000164	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551000165	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
1006551000166	Walker A/P-loop; other site
1006551000167	ATP binding site [chemical binding]; other site
1006551000168	Q-loop/lid; other site
1006551000169	ABC transporter signature motif; other site
1006551000170	Walker B; other site
1006551000171	D-loop; other site
1006551000172	H-loop/switch region; other site
1006551000173	Haem-binding domain; Region: Haem_bd; pfam14376
1006551000174	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
1006551000175	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551000176	putative substrate translocation pore; other site
1006551000177	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
1006551000178	classical (c) SDRs; Region: SDR_c; cd05233
1006551000179	NAD(P) binding site [chemical binding]; other site
1006551000180	active site
1006551000181	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1006551000182	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551000183	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
1006551000184	dimerization interface [polypeptide binding]; other site
1006551000185	substrate binding pocket [chemical binding]; other site
1006551000186	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551000187	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1006551000188	substrate binding pocket [chemical binding]; other site
1006551000189	membrane-bound complex binding site; other site
1006551000190	hinge residues; other site
1006551000191	Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and...; Region: LbH_XAT; cd03349
1006551000192	trimer interface [polypeptide binding]; other site
1006551000193	active site
1006551000194	substrate binding site [chemical binding]; other site
1006551000195	CoA binding site [chemical binding]; other site
1006551000196	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1006551000197	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1006551000198	PapC N-terminal domain; Region: PapC_N; pfam13954
1006551000199	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1006551000200	PapC C-terminal domain; Region: PapC_C; pfam13953
1006551000201	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1006551000202	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1006551000203	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1006551000204	Fimbrial protein; Region: Fimbrial; cl01416
1006551000205	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
1006551000206	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1006551000207	NAD(P) binding site [chemical binding]; other site
1006551000208	catalytic residues [active]
1006551000209	Transcriptional activator of acetoin/glycerol metabolism [Secondary metabolites biosynthesis, transport, and catabolism / Transcription]; Region: AcoR; COG3284
1006551000210	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1006551000211	Walker A motif; other site
1006551000212	ATP binding site [chemical binding]; other site
1006551000213	Walker B motif; other site
1006551000214	arginine finger; other site
1006551000215	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1006551000216	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1006551000217	dimerization interface [polypeptide binding]; other site
1006551000218	putative DNA binding site [nucleotide binding]; other site
1006551000219	putative Zn2+ binding site [ion binding]; other site
1006551000220	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
1006551000221	active site residue [active]
1006551000222	DNA-binding protein H-NS [General function prediction only]; Region: Hns; COG2916
1006551000223	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
1006551000224	Protein of unknown function (DUF1144); Region: DUF1144; pfam06610
1006551000225	hypothetical protein; Provisional; Region: PRK10556
1006551000226	Bacterial protein of unknown function (DUF883); Region: DUF883; cl01888
1006551000227	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1006551000228	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551000229	DNA-binding site [nucleotide binding]; DNA binding site
1006551000230	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1006551000231	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551000232	homodimer interface [polypeptide binding]; other site
1006551000233	catalytic residue [active]
1006551000234	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
1006551000235	Uncharacterized conserved protein [Function unknown]; Region: COG2128
1006551000236	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
1006551000237	catalytic residues [active]
1006551000238	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
1006551000239	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
1006551000240	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
1006551000241	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1006551000242	active site
1006551000243	dimer interface [polypeptide binding]; other site
1006551000244	catalytic residues [active]
1006551000245	effector binding site; other site
1006551000246	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
1006551000247	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
1006551000248	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1006551000249	dimer interface [polypeptide binding]; other site
1006551000250	putative radical transfer pathway; other site
1006551000251	diiron center [ion binding]; other site
1006551000252	tyrosyl radical; other site
1006551000253	glycine betaine transporter ATP-binding subunit; Provisional; Region: PRK10070
1006551000254	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
1006551000255	Walker A/P-loop; other site
1006551000256	ATP binding site [chemical binding]; other site
1006551000257	Q-loop/lid; other site
1006551000258	ABC transporter signature motif; other site
1006551000259	Walker B; other site
1006551000260	D-loop; other site
1006551000261	H-loop/switch region; other site
1006551000262	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
1006551000263	glycine betaine transporter membrane protein; Provisional; Region: PRK10952
1006551000264	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551000265	dimer interface [polypeptide binding]; other site
1006551000266	conserved gate region; other site
1006551000267	putative PBP binding loops; other site
1006551000268	ABC-ATPase subunit interface; other site
1006551000269	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
1006551000270	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1006551000271	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
1006551000272	putative L-valine exporter; Provisional; Region: PRK10408
1006551000273	transcriptional repressor MprA; Provisional; Region: PRK10870
1006551000274	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1006551000275	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
1006551000276	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1006551000277	HlyD family secretion protein; Region: HlyD_3; pfam13437
1006551000278	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1006551000279	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551000280	putative substrate translocation pore; other site
1006551000281	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551000282	2-isopropylmalate synthase; Validated; Region: PRK03739
1006551000283	Mycobacterium tuberculosis LeuA3 and related proteins, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_LeuA; cd07942
1006551000284	active site
1006551000285	catalytic residues [active]
1006551000286	metal binding site [ion binding]; metal-binding site
1006551000287	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; smart00917
1006551000288	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1006551000289	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1006551000290	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551000291	S-ribosylhomocysteinase; Provisional; Region: PRK02260
1006551000292	glutamate--cysteine ligase; Provisional; Region: PRK02107
1006551000293	Predicted membrane protein [Function unknown]; Region: COG1238
1006551000294	fructose-1-P/6-phosphogluconate phosphatase; Provisional; Region: PRK10725
1006551000295	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1006551000296	motif II; other site
1006551000297	BON domain; Region: BON; pfam04972
1006551000298	carbon storage regulator; Provisional; Region: PRK01712
1006551000299	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1006551000300	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1006551000301	motif 1; other site
1006551000302	active site
1006551000303	motif 2; other site
1006551000304	motif 3; other site
1006551000305	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1006551000306	DHHA1 domain; Region: DHHA1; pfam02272
1006551000307	recombination regulator RecX; Reviewed; Region: recX; PRK00117
1006551000308	recombinase A; Provisional; Region: recA; PRK09354
1006551000309	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1006551000310	hexamer interface [polypeptide binding]; other site
1006551000311	Walker A motif; other site
1006551000312	ATP binding site [chemical binding]; other site
1006551000313	Walker B motif; other site
1006551000314	hypothetical protein; Validated; Region: PRK03661
1006551000315	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
1006551000316	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
1006551000317	metal binding site [ion binding]; metal-binding site
1006551000318	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1006551000319	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1006551000320	ABC-ATPase subunit  interface; other site
1006551000321	dimer interface [polypeptide binding]; other site
1006551000322	putative PBP binding regions; other site
1006551000323	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1006551000324	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1006551000325	Transglycosylase SLT domain; Region: SLT_2; pfam13406
1006551000326	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1006551000327	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1006551000328	catalytic residue [active]
1006551000329	PTS system enzyme II sorbitol-specific factor; Region: EII-GUT; cl01515
1006551000330	PTS system, glucitol/sorbitol-specific, IIBC component; Region: EIIBC-GUT; TIGR00825
1006551000331	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
1006551000332	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
1006551000333	PTS system glucitol/sorbitol-specific transporter subunit IIA; Provisional; Region: PRK10377
1006551000334	sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384
1006551000335	Sorbitol 6-phosphate dehydrogenase (SDH), classical (c) SDRs; Region: SDH_SDR_c_like; cd05322
1006551000336	putative NAD(P) binding site [chemical binding]; other site
1006551000337	active site
1006551000338	DNA-binding transcriptional activator GutM; Provisional; Region: PRK10234
1006551000339	DNA-bindng transcriptional repressor SrlR; Provisional; Region: srlR; PRK10434
1006551000340	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1006551000341	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1006551000342	D-arabinose 5-phosphate isomerase; Provisional; Region: gutQ; PRK11543
1006551000343	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1006551000344	putative active site [active]
1006551000345	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1006551000346	anaerobic nitric oxide reductase transcription regulator; Provisional; Region: PRK05022
1006551000347	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1006551000348	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1006551000349	Walker A motif; other site
1006551000350	ATP binding site [chemical binding]; other site
1006551000351	Walker B motif; other site
1006551000352	arginine finger; other site
1006551000353	anaerobic nitric oxide reductase flavorubredoxin; Provisional; Region: PRK05452
1006551000354	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1006551000355	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1006551000356	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
1006551000357	iron binding site [ion binding]; other site
1006551000358	NADH:flavorubredoxin oxidoreductase; Provisional; Region: PRK04965
1006551000359	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1006551000360	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1006551000361	High-affinity nickel permease [Inorganic ion transport and metabolism]; Region: HoxN; COG3376
1006551000362	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
1006551000363	Acylphosphatase; Region: Acylphosphatase; pfam00708
1006551000364	HypF finger; Region: zf-HYPF; pfam07503
1006551000365	HypF finger; Region: zf-HYPF; pfam07503
1006551000366	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
1006551000367	formate dehydrogenase-H ferredoxin subunit; Provisional; Region: PRK10330
1006551000368	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1006551000369	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1006551000370	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1006551000371	DNA binding site [nucleotide binding]
1006551000372	domain linker motif; other site
1006551000373	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1006551000374	dimerization interface (closed form) [polypeptide binding]; other site
1006551000375	ligand binding site [chemical binding]; other site
1006551000376	PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC; Provisional; Region: PRK09796
1006551000377	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1006551000378	active site turn [active]
1006551000379	phosphorylation site [posttranslational modification]
1006551000380	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
1006551000381	cryptic 6-phospho-beta-glucosidase; Provisional; Region: PRK09852
1006551000382	beta-galactosidase; Region: BGL; TIGR03356
1006551000383	Endopeptidases belonging to membrane-bound hydrogen evolving hydrogenase group. In hydrogenase 3 from E coli, the maturation of the large subunit (HycE) requires the cleavage of a C-terminal peptide by the endopeptidase HycI, before the final formation...; Region: H2MP_MemB-H2evol; cd06067
1006551000384	nickel binding site [ion binding]; other site
1006551000385	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
1006551000386	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
1006551000387	formate hydrogenlyase complex iron-sulfur subunit; Provisional; Region: PRK12387
1006551000388	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1006551000389	potential frameshift: common BLAST hit: gi|288933889|ref|YP_003437948.1| NADH dehydrogenase (ubiquinone) 30 kDa subunit
1006551000390	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
1006551000391	NADH dehydrogenase; Region: NADHdh; cl00469
1006551000392	formate hydrogenlyase subunit 3; Reviewed; Region: PRK08042
1006551000393	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1006551000394	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
1006551000395	Transcriptional repressor of hyc and hyp operons; Region: HycA_repressor; pfam11046
1006551000396	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
1006551000397	hydrogenase nickel incorporation protein; Validated; Region: hypA; PRK03681
1006551000398	hydrogenase nickel incorporation protein HypB; Provisional; Region: PRK10463
1006551000399	hydrogenase assembly chaperone; Provisional; Region: PRK10409
1006551000400	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
1006551000401	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
1006551000402	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
1006551000403	dimerization interface [polypeptide binding]; other site
1006551000404	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
1006551000405	ATP binding site [chemical binding]; other site
1006551000406	formate hydrogenlyase transcriptional activator FhlA; Provisional; Region: PRK15429
1006551000407	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1006551000408	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1006551000409	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1006551000410	Walker A motif; other site
1006551000411	ATP binding site [chemical binding]; other site
1006551000412	Walker B motif; other site
1006551000413	arginine finger; other site
1006551000414	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
1006551000415	Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657
1006551000416	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1006551000417	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1006551000418	beta-galactosidase; Region: BGL; TIGR03356
1006551000419	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1006551000420	Carbohydrate Binding Module 6 (CBM6) domains; many are found in association with discoidin domain(s); Region: CBM6_discoidin-like; cd04083
1006551000421	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1006551000422	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1006551000423	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1006551000424	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1006551000425	active site
1006551000426	P-loop; other site
1006551000427	phosphorylation site [posttranslational modification]
1006551000428	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1006551000429	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1006551000430	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1006551000431	methionine cluster; other site
1006551000432	active site
1006551000433	phosphorylation site [posttranslational modification]
1006551000434	metal binding site [ion binding]; metal-binding site
1006551000435	fructokinase; Reviewed; Region: PRK09557
1006551000436	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1006551000437	nucleotide binding site [chemical binding]; other site
1006551000438	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1006551000439	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1006551000440	DNA binding site [nucleotide binding]
1006551000441	domain linker motif; other site
1006551000442	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1006551000443	ligand binding site [chemical binding]; other site
1006551000444	dimerization interface [polypeptide binding]; other site
1006551000445	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
1006551000446	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
1006551000447	metal binding site [ion binding]; metal-binding site
1006551000448	manganese/iron transporter ATP-binding protein; Provisional; Region: PRK15056
1006551000449	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1006551000450	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1006551000451	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1006551000452	ABC-ATPase subunit  interface; other site
1006551000453	dimer interface [polypeptide binding]; other site
1006551000454	putative PBP binding regions; other site
1006551000455	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1006551000456	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1006551000457	ABC-ATPase subunit  interface; other site
1006551000458	dimer interface [polypeptide binding]; other site
1006551000459	putative PBP binding regions; other site
1006551000460	Nitrous oxide-stimulated promoter; Region: YgbA_NO; pfam11756
1006551000461	Rdx family; Region: Rdx; cl01407
1006551000462	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
1006551000463	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1006551000464	N-terminal plug; other site
1006551000465	ligand-binding site [chemical binding]; other site
1006551000466	Putative heme degradation protein [Inorganic ion transport and metabolism]; Region: HemS; COG3720
1006551000467	Haemin-degrading HemS.ChuX domain; Region: HemS; pfam05171
1006551000468	Haemin-degrading HemS.ChuX domain; Region: HemS; pfam05171
1006551000469	Hemin binding protein HutB.  These proteins have been shown to function as initial receptors in ABC transport of hemin and hemoproteins in many eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a...; Region: HutB; cd01149
1006551000470	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1006551000471	putative hemin binding site; other site
1006551000472	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1006551000473	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1006551000474	ABC-ATPase subunit  interface; other site
1006551000475	dimer interface [polypeptide binding]; other site
1006551000476	putative PBP binding regions; other site
1006551000477	hemin importer ATP-binding subunit; Provisional; Region: hmuV; PRK13548
1006551000478	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1006551000479	Walker A/P-loop; other site
1006551000480	ATP binding site [chemical binding]; other site
1006551000481	Q-loop/lid; other site
1006551000482	ABC transporter signature motif; other site
1006551000483	Walker B; other site
1006551000484	D-loop; other site
1006551000485	H-loop/switch region; other site
1006551000486	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
1006551000487	Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion; Region: enolase_like; cl17188
1006551000488	metal binding site [ion binding]; metal-binding site
1006551000489	substrate binding pocket [chemical binding]; other site
1006551000490	gluconate 5-dehydrogenase; Provisional; Region: PRK08085
1006551000491	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1006551000492	NADP binding site [chemical binding]; other site
1006551000493	homodimer interface [polypeptide binding]; other site
1006551000494	active site
1006551000495	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551000496	L-idonate 5-dehydrogenase; Provisional; Region: PRK09880
1006551000497	L-idonate 5-dehydrogenase; Region: idonate-5-DH; cd08232
1006551000498	putative NAD(P) binding site [chemical binding]; other site
1006551000499	catalytic Zn binding site [ion binding]; other site
1006551000500	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1006551000501	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551000502	DNA-binding site [nucleotide binding]; DNA binding site
1006551000503	FCD domain; Region: FCD; pfam07729
1006551000504	L-1,2-propanediol oxidoreductase; Provisional; Region: PRK10624
1006551000505	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
1006551000506	dimer interface [polypeptide binding]; other site
1006551000507	active site
1006551000508	metal binding site [ion binding]; metal-binding site
1006551000509	FaeA-like protein; Region: FaeA; pfam04703
1006551000510	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
1006551000511	DNA binding site [nucleotide binding]
1006551000512	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1006551000513	Zn2+ binding site [ion binding]; other site
1006551000514	Mg2+ binding site [ion binding]; other site
1006551000515	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1006551000516	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1006551000517	NAD(P) binding site [chemical binding]; other site
1006551000518	active site
1006551000519	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1006551000520	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
1006551000521	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1006551000522	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
1006551000523	dimer interface [polypeptide binding]; other site
1006551000524	active site
1006551000525	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
1006551000526	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
1006551000527	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1006551000528	Walker A/P-loop; other site
1006551000529	ATP binding site [chemical binding]; other site
1006551000530	Q-loop/lid; other site
1006551000531	ABC transporter signature motif; other site
1006551000532	Walker B; other site
1006551000533	D-loop; other site
1006551000534	H-loop/switch region; other site
1006551000535	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1006551000536	FtsX-like permease family; Region: FtsX; pfam02687
1006551000537	macrolide transporter subunit MacA; Provisional; Region: PRK11578
1006551000538	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1006551000539	HlyD family secretion protein; Region: HlyD_3; pfam13437
1006551000540	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
1006551000541	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296
1006551000542	putative active site [active]
1006551000543	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1006551000544	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551000545	Walker A/P-loop; other site
1006551000546	ATP binding site [chemical binding]; other site
1006551000547	Q-loop/lid; other site
1006551000548	ABC transporter signature motif; other site
1006551000549	Walker B; other site
1006551000550	D-loop; other site
1006551000551	H-loop/switch region; other site
1006551000552	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cl17185
1006551000553	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
1006551000554	catalytic residues [active]
1006551000555	hinge region; other site
1006551000556	alpha helical domain; other site
1006551000557	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315
1006551000558	dimerization interface [polypeptide binding]; other site
1006551000559	DNA binding residues [nucleotide binding]
1006551000560	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1006551000561	Fimbrial protein; Region: Fimbrial; cl01416
1006551000562	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1006551000563	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1006551000564	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1006551000565	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1006551000566	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
1006551000567	PapC N-terminal domain; Region: PapC_N; pfam13954
1006551000568	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1006551000569	PapC C-terminal domain; Region: PapC_C; pfam13953
1006551000570	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1006551000571	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1006551000572	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
1006551000573	MutS domain I; Region: MutS_I; pfam01624
1006551000574	MutS domain II; Region: MutS_II; pfam05188
1006551000575	MutS domain III; Region: MutS_III; pfam05192
1006551000576	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
1006551000577	Walker A/P-loop; other site
1006551000578	ATP binding site [chemical binding]; other site
1006551000579	Q-loop/lid; other site
1006551000580	ABC transporter signature motif; other site
1006551000581	Walker B; other site
1006551000582	D-loop; other site
1006551000583	H-loop/switch region; other site
1006551000584	Hok/gef family; Region: HOK_GEF; pfam01848
1006551000585	Protein of unknown function (DUF1062); Region: DUF1062; cl01786
1006551000586	3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases [Coenzyme metabolism]; Region: UbiD; COG0043
1006551000587	3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme metabolism]; Region: UbiX; COG0163
1006551000588	Flavoprotein; Region: Flavoprotein; pfam02441
1006551000589	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1006551000590	MarR family; Region: MarR_2; cl17246
1006551000591	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551000592	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551000593	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1006551000594	putative effector binding pocket; other site
1006551000595	dimerization interface [polypeptide binding]; other site
1006551000596	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1006551000597	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551000598	putative substrate translocation pore; other site
1006551000599	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4460
1006551000600	RNA polymerase sigma factor RpoS; Validated; Region: PRK05657
1006551000601	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1006551000602	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1006551000603	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1006551000604	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1006551000605	DNA binding residues [nucleotide binding]
1006551000606	lipoprotein NlpD; Provisional; Region: nlpD; PRK10871
1006551000607	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1006551000608	Peptidase family M23; Region: Peptidase_M23; pfam01551
1006551000609	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
1006551000610	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551000611	S-adenosylmethionine binding site [chemical binding]; other site
1006551000612	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
1006551000613	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
1006551000614	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
1006551000615	Permutation of conserved domain; other site
1006551000616	active site
1006551000617	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
1006551000618	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
1006551000619	homotrimer interaction site [polypeptide binding]; other site
1006551000620	zinc binding site [ion binding]; other site
1006551000621	CDP-binding sites; other site
1006551000622	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
1006551000623	substrate binding site; other site
1006551000624	dimer interface; other site
1006551000625	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
1006551000626	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
1006551000627	Protein of unknown function (DUF3561); Region: DUF3561; pfam12084
1006551000628	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
1006551000629	ligand-binding site [chemical binding]; other site
1006551000630	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
1006551000631	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
1006551000632	CysD dimerization site [polypeptide binding]; other site
1006551000633	G1 box; other site
1006551000634	putative GEF interaction site [polypeptide binding]; other site
1006551000635	GTP/Mg2+ binding site [chemical binding]; other site
1006551000636	Switch I region; other site
1006551000637	G2 box; other site
1006551000638	G3 box; other site
1006551000639	Switch II region; other site
1006551000640	G4 box; other site
1006551000641	G5 box; other site
1006551000642	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
1006551000643	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
1006551000644	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
1006551000645	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1006551000646	Active Sites [active]
1006551000647	siroheme synthase; Provisional; Region: cysG; PRK10637
1006551000648	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
1006551000649	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
1006551000650	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
1006551000651	active site
1006551000652	SAM binding site [chemical binding]; other site
1006551000653	homodimer interface [polypeptide binding]; other site
1006551000654	alkaline phosphatase isozyme conversion aminopeptidase; Provisional; Region: PRK10199
1006551000655	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
1006551000656	metal binding site [ion binding]; metal-binding site
1006551000657	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
1006551000658	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1006551000659	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
1006551000660	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1006551000661	Active Sites [active]
1006551000662	sulfite reductase subunit beta; Provisional; Region: PRK13504
1006551000663	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1006551000664	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1006551000665	sulfite reductase subunit alpha; Provisional; Region: cysJ; PRK10953
1006551000666	Flavodoxin; Region: Flavodoxin_1; pfam00258
1006551000667	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
1006551000668	FAD binding pocket [chemical binding]; other site
1006551000669	FAD binding motif [chemical binding]; other site
1006551000670	catalytic residues [active]
1006551000671	NAD binding pocket [chemical binding]; other site
1006551000672	phosphate binding motif [ion binding]; other site
1006551000673	beta-alpha-beta structure motif; other site
1006551000674	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
1006551000675	active site
1006551000676	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
1006551000677	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
1006551000678	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1006551000679	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
1006551000680	NAD(P) binding site [chemical binding]; other site
1006551000681	active site
1006551000682	enolase; Provisional; Region: eno; PRK00077
1006551000683	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
1006551000684	dimer interface [polypeptide binding]; other site
1006551000685	metal binding site [ion binding]; metal-binding site
1006551000686	substrate binding pocket [chemical binding]; other site
1006551000687	CTP synthetase; Validated; Region: pyrG; PRK05380
1006551000688	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
1006551000689	Catalytic site [active]
1006551000690	active site
1006551000691	UTP binding site [chemical binding]; other site
1006551000692	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
1006551000693	active site
1006551000694	putative oxyanion hole; other site
1006551000695	catalytic triad [active]
1006551000696	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
1006551000697	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
1006551000698	homodimer interface [polypeptide binding]; other site
1006551000699	metal binding site [ion binding]; metal-binding site
1006551000700	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
1006551000701	homodimer interface [polypeptide binding]; other site
1006551000702	active site
1006551000703	putative chemical substrate binding site [chemical binding]; other site
1006551000704	metal binding site [ion binding]; metal-binding site
1006551000705	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
1006551000706	HD domain; Region: HD_4; pfam13328
1006551000707	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1006551000708	synthetase active site [active]
1006551000709	NTP binding site [chemical binding]; other site
1006551000710	metal binding site [ion binding]; metal-binding site
1006551000711	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1006551000712	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1006551000713	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
1006551000714	TRAM domain; Region: TRAM; pfam01938
1006551000715	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551000716	S-adenosylmethionine binding site [chemical binding]; other site
1006551000717	hybrid sensory histidine kinase BarA; Provisional; Region: PRK11107
1006551000718	Uncharacterized signal transduction histidine kinase domain (DUF2222); Region: DUF2222; pfam09984
1006551000719	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1006551000720	dimerization interface [polypeptide binding]; other site
1006551000721	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1006551000722	dimer interface [polypeptide binding]; other site
1006551000723	phosphorylation site [posttranslational modification]
1006551000724	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551000725	ATP binding site [chemical binding]; other site
1006551000726	Mg2+ binding site [ion binding]; other site
1006551000727	G-X-G motif; other site
1006551000728	Uncharacterized domain of BarA-like signal transduction histidine kinases [Signal transduction mechanisms]; Region: COG4999
1006551000729	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551000730	active site
1006551000731	phosphorylation site [posttranslational modification]
1006551000732	intermolecular recognition site; other site
1006551000733	dimerization interface [polypeptide binding]; other site
1006551000734	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1006551000735	putative binding surface; other site
1006551000736	active site
1006551000737	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
1006551000738	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
1006551000739	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
1006551000740	active site
1006551000741	tetramer interface [polypeptide binding]; other site
1006551000742	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
1006551000743	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
1006551000744	active site
1006551000745	tetramer interface [polypeptide binding]; other site
1006551000746	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551000747	D-galactonate transporter; Region: 2A0114; TIGR00893
1006551000748	putative substrate translocation pore; other site
1006551000749	flavodoxin; Provisional; Region: PRK08105
1006551000750	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1006551000751	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
1006551000752	probable active site [active]
1006551000753	tRNA pseudouridine synthase C; Region: DUF446; pfam04287
1006551000754	SecY interacting protein Syd; Provisional; Region: PRK04968
1006551000755	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
1006551000756	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
1006551000757	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
1006551000758	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
1006551000759	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
1006551000760	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1006551000761	serine transporter; Region: stp; TIGR00814
1006551000762	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
1006551000763	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1006551000764	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1006551000765	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
1006551000766	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551000767	substrate binding pocket [chemical binding]; other site
1006551000768	membrane-bound complex binding site; other site
1006551000769	FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family; Region: FMN_nitrolo; TIGR03860
1006551000770	nitrilotriacetate monoxygenase oxidizes nitrilotriacetate utilizing reduced flavin mononucleotide (FMNH2) and oxygen. The FMNH2 is provided by an NADH:flavin mononucleotide (FMN) oxidorductase that uses NADH to reduce FMN to FMNH2; Region: Nitrilotriacetate_monoxgenase; cd01095
1006551000771	active site
1006551000772	non-prolyl cis peptide bond; other site
1006551000773	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4529
1006551000774	FAD-NAD(P)-binding; Region: NAD_binding_9; pfam13454
1006551000775	alkanesulfonate monooxygenase; Provisional; Region: PRK00719
1006551000776	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
1006551000777	active site
1006551000778	dimer interface [polypeptide binding]; other site
1006551000779	non-prolyl cis peptide bond; other site
1006551000780	insertion regions; other site
1006551000781	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cd00368
1006551000782	psp operon transcriptional activator PspF; Region: phageshock_pspF; TIGR02974
1006551000783	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1006551000784	Walker A motif; other site
1006551000785	ATP binding site [chemical binding]; other site
1006551000786	Walker B motif; other site
1006551000787	arginine finger; other site
1006551000788	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1006551000789	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
1006551000790	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551000791	substrate binding pocket [chemical binding]; other site
1006551000792	membrane-bound complex binding site; other site
1006551000793	hinge residues; other site
1006551000794	flap endonuclease-like protein; Provisional; Region: PRK09482
1006551000795	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1006551000796	active site
1006551000797	metal binding site 1 [ion binding]; metal-binding site
1006551000798	putative 5' ssDNA interaction site; other site
1006551000799	metal binding site 3; metal-binding site
1006551000800	metal binding site 2 [ion binding]; metal-binding site
1006551000801	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1006551000802	putative DNA binding site [nucleotide binding]; other site
1006551000803	putative metal binding site [ion binding]; other site
1006551000804	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1006551000805	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1006551000806	intersubunit interface [polypeptide binding]; other site
1006551000807	active site
1006551000808	Zn2+ binding site [ion binding]; other site
1006551000809	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
1006551000810	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551000811	putative substrate translocation pore; other site
1006551000812	L-fucose isomerase; Provisional; Region: fucI; PRK10991
1006551000813	L-fucose isomerase (FucIase); FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose during glycolysis). L-fucose (or 6-deoxy-L-galactose) is found in blood group...; Region: L-fucose_isomerase; cd03556
1006551000814	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1006551000815	trimer interface [polypeptide binding]; other site
1006551000816	substrate binding site [chemical binding]; other site
1006551000817	Mn binding site [ion binding]; other site
1006551000818	L-fuculokinase; Provisional; Region: PRK10331
1006551000819	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1006551000820	nucleotide binding site [chemical binding]; other site
1006551000821	L-fucose mutarotase; Provisional; Region: fucU; PRK15420
1006551000822	DNA-binding transcriptional activator FucR; Provisional; Region: PRK10411
1006551000823	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1006551000824	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1006551000825	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
1006551000826	FtsJ-like methyltransferase; Region: FtsJ; cl17430
1006551000827	hypothetical protein; Provisional; Region: PRK10873
1006551000828	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1006551000829	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551000830	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
1006551000831	dimerization interface [polypeptide binding]; other site
1006551000832	substrate binding pocket [chemical binding]; other site
1006551000833	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1006551000834	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1006551000835	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1006551000836	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1006551000837	catalytic residue [active]
1006551000838	Fe-S metabolism associated domain; Region: SufE; cl00951
1006551000839	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
1006551000840	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
1006551000841	putative ATP binding site [chemical binding]; other site
1006551000842	putative substrate interface [chemical binding]; other site
1006551000843	murein transglycosylase A; Provisional; Region: mltA; PRK11162
1006551000844	MltA specific insert domain; Region: MltA; pfam03562
1006551000845	3D domain; Region: 3D; pfam06725
1006551000846	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
1006551000847	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
1006551000848	putative dimer interface [polypeptide binding]; other site
1006551000849	active site pocket [active]
1006551000850	putative cataytic base [active]
1006551000851	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
1006551000852	homotrimer interface [polypeptide binding]; other site
1006551000853	Walker A motif; other site
1006551000854	GTP binding site [chemical binding]; other site
1006551000855	Walker B motif; other site
1006551000856	cobyric acid synthase; Provisional; Region: PRK00784
1006551000857	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1006551000858	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1006551000859	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
1006551000860	catalytic triad [active]
1006551000861	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13638
1006551000862	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1006551000863	Walker A/P-loop; other site
1006551000864	ATP binding site [chemical binding]; other site
1006551000865	Q-loop/lid; other site
1006551000866	ABC transporter signature motif; other site
1006551000867	Walker B; other site
1006551000868	D-loop; other site
1006551000869	H-loop/switch region; other site
1006551000870	cobalt transport protein CbiQ; Provisional; Region: PRK15485
1006551000871	cobalt transport protein CbiN; Provisional; Region: PRK02898
1006551000872	cobalt transport protein CbiM; Validated; Region: PRK08319
1006551000873	Cobalt uptake substrate-specific transmembrane region; Region: CbiM; pfam01891
1006551000874	Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645
1006551000875	active site
1006551000876	SAM binding site [chemical binding]; other site
1006551000877	homodimer interface [polypeptide binding]; other site
1006551000878	Cobalamin biosynthesis protein CbiK, Co2+ chelatase [Coenzyme metabolism]; Region: CbiK; COG4822
1006551000879	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), N-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_N; cd03412
1006551000880	active site
1006551000881	C-terminal domain interface [polypeptide binding]; other site
1006551000882	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), C-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_C; cd03413
1006551000883	active site
1006551000884	N-terminal domain interface [polypeptide binding]; other site
1006551000885	cobalt-precorrin-6x reductase; Reviewed; Region: PRK08057
1006551000886	Precorrin-6x reductase [Coenzyme metabolism]; Region: CobK; COG2099
1006551000887	Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646
1006551000888	active site
1006551000889	SAM binding site [chemical binding]; other site
1006551000890	homodimer interface [polypeptide binding]; other site
1006551000891	cobalamin biosynthesis protein CbiG; Validated; Region: PRK05788
1006551000892	Cobalamin synthesis G N-terminal; Region: CbiG_N; pfam11760
1006551000893	Cobalamin biosynthesis central region; Region: CbiG_mid; pfam11761
1006551000894	Cobalamin synthesis G C-terminus; Region: CbiG_C; pfam01890
1006551000895	Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641
1006551000896	active site
1006551000897	SAM binding site [chemical binding]; other site
1006551000898	homodimer interface [polypeptide binding]; other site
1006551000899	cobalt-precorrin-6Y C(15)-methyltransferase; Validated; Region: PRK08287
1006551000900	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551000901	S-adenosylmethionine binding site [chemical binding]; other site
1006551000902	Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644
1006551000903	active site
1006551000904	putative homodimer interface [polypeptide binding]; other site
1006551000905	SAM binding site [chemical binding]; other site
1006551000906	cobalt-precorrin-6A synthase; Reviewed; Region: cbiD; PRK00075
1006551000907	cobalt-precorrin-8X methylmutase; Validated; Region: cbiC; PRK08286
1006551000908	Precorrin-8X methylmutase; Region: CbiC; pfam02570
1006551000909	cobalamin biosynthesis protein; Provisional; Region: cobD; PRK01209
1006551000910	cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077
1006551000911	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
1006551000912	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyrinic Acid a,c-Diamide Synthase; Region: GATase1_CobB; cd03130
1006551000913	catalytic triad [active]
1006551000914	Predicted sensor domain [Signal transduction mechanisms / Transcription]; Region: PocR; COG4936
1006551000915	Sensory domain found in PocR; Region: PocR; pfam10114
1006551000916	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1006551000917	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551000918	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551000919	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1006551000920	amphipathic channel; other site
1006551000921	Asn-Pro-Ala signature motifs; other site
1006551000922	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1006551000923	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
1006551000924	Hexamer interface [polypeptide binding]; other site
1006551000925	Putative hexagonal pore residue; other site
1006551000926	propanediol utilization protein PduB; Provisional; Region: PRK15415
1006551000927	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduB_repeat1; cd07047
1006551000928	putative hexamer interface [polypeptide binding]; other site
1006551000929	putative hexagonal pore; other site
1006551000930	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduB_repeat2; cd07048
1006551000931	putative hexamer interface [polypeptide binding]; other site
1006551000932	putative hexagonal pore; other site
1006551000933	Propanediol dehydratase, large subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduC; COG4909
1006551000934	Dehydratase large subunit. This family contains the large (alpha) subunit of B12-dependent glycerol dehydratases (GDHs) and B12-dependent diol dehydratases (DDHs). GDH is isofunctional with DDH. These enzymes can each catalyze the conversion of 1; Region: Dehydratase_LU; cd03687
1006551000935	alpha-alpha subunit/dimer interface [polypeptide binding]; other site
1006551000936	alpha-beta subunit interface [polypeptide binding]; other site
1006551000937	alpha-gamma subunit interface [polypeptide binding]; other site
1006551000938	active site
1006551000939	substrate and K+ binding site; other site
1006551000940	K+ binding site [ion binding]; other site
1006551000941	cobalamin binding site [chemical binding]; other site
1006551000942	propanediol dehydratase medium subunit; Provisional; Region: pduD; PRK15042
1006551000943	Propanediol dehydratase, small subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduE; COG4910
1006551000944	Diol dehydratase reactivase ATPase-like domain; Region: DDR; pfam08841
1006551000945	Dehydratase medium subunit; Region: Dehydratase_MU; pfam02288
1006551000946	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1006551000947	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
1006551000948	Hexamer interface [polypeptide binding]; other site
1006551000949	Putative hexagonal pore residue; other site
1006551000950	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1006551000951	1,2-propanediol utilization protein K (PduK), Bacterial Micro-Compartment (BMC) domain repeat 1l; Region: BMC_PduK; cd07056
1006551000952	putative hexamer interface [polypeptide binding]; other site
1006551000953	putative hexagonal pore; other site
1006551000954	propanediol utilization phosphotransacylase; Provisional; Region: PRK15070
1006551000955	Propanediol utilisation protein PduL; Region: PduL; pfam06130
1006551000956	Propanediol utilisation protein PduL; Region: PduL; pfam06130
1006551000957	putative propanediol utilization protein PduM; Provisional; Region: PRK15428
1006551000958	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cl01889
1006551000959	Hexamer/Pentamer interface [polypeptide binding]; other site
1006551000960	central pore; other site
1006551000961	cob(I)alamin adenosyltransferase [Coenzyme transport and    metabolism]; Region: COG2096
1006551000962	Uncharacterized protein, possibly involved in utilization of glycolate and propanediol [General function prediction only]; Region: GlcG; COG3193
1006551000963	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
1006551000964	putative catalytic cysteine [active]
1006551000965	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
1006551000966	1,3-propanediol dehydrogenase (PPD) catalyzes the reduction of 3-hydroxypropionaldehyde (3-HPA) to 1,3-propanediol in glycerol metabolism; Region: PDD; cd08180
1006551000967	putative active site [active]
1006551000968	metal binding site [ion binding]; metal-binding site
1006551000969	Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512
1006551000970	SLBB domain; Region: SLBB; pfam10531
1006551000971	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
1006551000972	RnfC Barrel sandwich hybrid domain; Region: RnfC_N; pfam13375
1006551000973	PduT-like ethanolamine utilization protein; Region: eut_PduT; TIGR02526
1006551000974	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduT_repeat1; cd07053
1006551000975	putative hexamer interface [polypeptide binding]; other site
1006551000976	putative hexagonal pore; other site
1006551000977	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduT_repeat2; cd07054
1006551000978	putative hexamer interface [polypeptide binding]; other site
1006551000979	putative hexagonal pore; other site
1006551000980	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
1006551000981	putative hexamer interface [polypeptide binding]; other site
1006551000982	putative hexagonal pore; other site
1006551000983	Ethanolamine utilisation - propanediol utilisation; Region: PduV-EutP; pfam10662
1006551000984	G3 box; other site
1006551000985	Switch II region; other site
1006551000986	GTP/Mg2+ binding site [chemical binding]; other site
1006551000987	G4 box; other site
1006551000988	G5 box; other site
1006551000989	propionate kinase; Reviewed; Region: PRK12397
1006551000990	propionate/acetate kinase; Provisional; Region: PRK12379
1006551000991	Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduX; COG4542
1006551000992	threonine-phosphate decarboxylase; Provisional; Region: PRK08056
1006551000993	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1006551000994	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551000995	homodimer interface [polypeptide binding]; other site
1006551000996	catalytic residue [active]
1006551000997	AMIN domain; Region: AMIN; pfam11741
1006551000998	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1006551000999	active site
1006551001000	metal binding site [ion binding]; metal-binding site
1006551001001	N-acetylglutamate synthase; Validated; Region: PRK05279
1006551001002	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
1006551001003	putative feedback inhibition sensing region; other site
1006551001004	putative nucleotide binding site [chemical binding]; other site
1006551001005	putative substrate binding site [chemical binding]; other site
1006551001006	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1006551001007	Coenzyme A binding pocket [chemical binding]; other site
1006551001008	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
1006551001009	AAA domain; Region: AAA_30; pfam13604
1006551001010	Family description; Region: UvrD_C_2; pfam13538
1006551001011	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
1006551001012	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
1006551001013	protease3; Provisional; Region: PRK15101
1006551001014	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1006551001015	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1006551001016	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1006551001017	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
1006551001018	Exonuclease V gamma subunit [DNA replication, recombination, and repair]; Region: RecC; COG1330
1006551001019	hypothetical protein; Provisional; Region: PRK10332
1006551001020	Prepilin peptidase dependent protein C term (DUF3728); Region: DUF3728; pfam12528
1006551001021	Protein of unknown function (DUF2509); Region: DUF2509; cl11672
1006551001022	hypothetical protein; Provisional; Region: PRK10557
1006551001023	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
1006551001024	hypothetical protein; Provisional; Region: PRK10506
1006551001025	thymidylate synthase; Reviewed; Region: thyA; PRK01827
1006551001026	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
1006551001027	dimerization interface [polypeptide binding]; other site
1006551001028	active site
1006551001029	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
1006551001030	fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061
1006551001031	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1006551001032	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1006551001033	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1006551001034	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1006551001035	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
1006551001036	putative active site [active]
1006551001037	Ap4A binding site [chemical binding]; other site
1006551001038	nudix motif; other site
1006551001039	putative metal binding site [ion binding]; other site
1006551001040	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
1006551001041	putative DNA-binding cleft [nucleotide binding]; other site
1006551001042	putative DNA clevage site; other site
1006551001043	molecular lever; other site
1006551001044	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1006551001045	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1006551001046	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1006551001047	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1006551001048	active site
1006551001049	catalytic tetrad [active]
1006551001050	lysophospholipid transporter LplT; Provisional; Region: PRK11195
1006551001051	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551001052	putative substrate translocation pore; other site
1006551001053	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
1006551001054	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1006551001055	putative acyl-acceptor binding pocket; other site
1006551001056	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
1006551001057	acyl-activating enzyme (AAE) consensus motif; other site
1006551001058	putative AMP binding site [chemical binding]; other site
1006551001059	DNA-binding transcriptional regulator GalR; Provisional; Region: PRK10727
1006551001060	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1006551001061	DNA binding site [nucleotide binding]
1006551001062	domain linker motif; other site
1006551001063	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1006551001064	dimerization interface (closed form) [polypeptide binding]; other site
1006551001065	ligand binding site [chemical binding]; other site
1006551001066	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1006551001067	Coenzyme A binding pocket [chemical binding]; other site
1006551001068	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
1006551001069	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551001070	DNA-binding site [nucleotide binding]; DNA binding site
1006551001071	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1006551001072	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1006551001073	beta-galactosidase; Region: BGL; TIGR03356
1006551001074	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1006551001075	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1006551001076	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1006551001077	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1006551001078	DNA binding site [nucleotide binding]
1006551001079	domain linker motif; other site
1006551001080	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1006551001081	dimerization interface (closed form) [polypeptide binding]; other site
1006551001082	ligand binding site [chemical binding]; other site
1006551001083	diaminopimelate decarboxylase; Provisional; Region: PRK11165
1006551001084	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
1006551001085	active site
1006551001086	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1006551001087	substrate binding site [chemical binding]; other site
1006551001088	catalytic residues [active]
1006551001089	dimer interface [polypeptide binding]; other site
1006551001090	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
1006551001091	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551001092	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1006551001093	dimerization interface [polypeptide binding]; other site
1006551001094	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1006551001095	putative fimbrial chaperone protein; Provisional; Region: PRK09918
1006551001096	putative fimbrial outer membrane usher protein; Provisional; Region: PRK15304
1006551001097	PapC N-terminal domain; Region: PapC_N; pfam13954
1006551001098	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1006551001099	PapC C-terminal domain; Region: PapC_C; pfam13953
1006551001100	hypothetical protein; Provisional; Region: PRK15301
1006551001101	Protein of unknown function (DUF1120); Region: DUF1120; cl05856
1006551001102	Protein of unknown function (DUF1120); Region: DUF1120; cl05856
1006551001103	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
1006551001104	aspartate racemase; Region: asp_race; TIGR00035
1006551001105	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
1006551001106	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551001107	dimer interface [polypeptide binding]; other site
1006551001108	conserved gate region; other site
1006551001109	putative PBP binding loops; other site
1006551001110	ABC-ATPase subunit interface; other site
1006551001111	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1006551001112	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551001113	dimer interface [polypeptide binding]; other site
1006551001114	conserved gate region; other site
1006551001115	putative PBP binding loops; other site
1006551001116	ABC-ATPase subunit interface; other site
1006551001117	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
1006551001118	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1006551001119	Walker A/P-loop; other site
1006551001120	ATP binding site [chemical binding]; other site
1006551001121	Q-loop/lid; other site
1006551001122	ABC transporter signature motif; other site
1006551001123	Walker B; other site
1006551001124	D-loop; other site
1006551001125	H-loop/switch region; other site
1006551001126	TOBE domain; Region: TOBE_2; pfam08402
1006551001127	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1006551001128	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1006551001129	Periplasmic component of the Tol biopolymer transport system [Intracellular trafficking and secretion]; Region: TolB; COG0823
1006551001130	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1006551001131	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
1006551001132	Beta-fructosidases (levanase/invertase) [Carbohydrate transport and metabolism]; Region: SacC; COG1621
1006551001133	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
1006551001134	substrate binding [chemical binding]; other site
1006551001135	active site
1006551001136	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
1006551001137	galactoside permease; Reviewed; Region: lacY; PRK09528
1006551001138	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1006551001139	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1006551001140	DNA binding site [nucleotide binding]
1006551001141	domain linker motif; other site
1006551001142	Ligand-binding domain of DNA-binding regulatory proteins specific to sucrose that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_sucrose_transcription_regulator; cd06288
1006551001143	putative dimerization interface [polypeptide binding]; other site
1006551001144	putative ligand binding site [chemical binding]; other site
1006551001145	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
1006551001146	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551001147	putative substrate translocation pore; other site
1006551001148	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551001149	2-deoxy-D-gluconate 3-dehydrogenase; Validated; Region: PRK08993
1006551001150	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1006551001151	NADP binding site [chemical binding]; other site
1006551001152	homodimer interface [polypeptide binding]; other site
1006551001153	active site
1006551001154	Periplasmic component of the Tol biopolymer transport system [Intracellular trafficking and secretion]; Region: TolB; COG0823
1006551001155	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1006551001156	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; cl11629
1006551001157	putative acyltransferase; Provisional; Region: PRK05790
1006551001158	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1006551001159	dimer interface [polypeptide binding]; other site
1006551001160	active site
1006551001161	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551001162	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551001163	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1006551001164	dimerization interface [polypeptide binding]; other site
1006551001165	Predicted membrane protein [Function unknown]; Region: COG4125
1006551001166	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
1006551001167	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
1006551001168	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1006551001169	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
1006551001170	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1006551001171	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1006551001172	active site
1006551001173	catalytic tetrad [active]
1006551001174	PilZ domain; Region: PilZ; pfam07238
1006551001175	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1006551001176	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1006551001177	DNA binding residues [nucleotide binding]
1006551001178	potential frameshift: common BLAST hit: gi|288933678|ref|YP_003437737.1| diguanylate phosphodiesterase
1006551001179	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1006551001180	putative major fimbrial protein SthE; Provisional; Region: PRK15292
1006551001181	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1006551001182	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1006551001183	PapC N-terminal domain; Region: PapC_N; pfam13954
1006551001184	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1006551001185	PapC C-terminal domain; Region: PapC_C; pfam13953
1006551001186	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1006551001187	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1006551001188	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1006551001189	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1006551001190	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1006551001191	putative DNA binding site [nucleotide binding]; other site
1006551001192	dimerization interface [polypeptide binding]; other site
1006551001193	putative Zn2+ binding site [ion binding]; other site
1006551001194	Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only]; Region: COG2329
1006551001195	Protein of unknown function (DUF1471); Region: DUF1471; cl11507
1006551001196	EamA-like transporter family; Region: EamA; pfam00892
1006551001197	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1006551001198	EamA-like transporter family; Region: EamA; pfam00892
1006551001199	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1006551001200	MarR family; Region: MarR; pfam01047
1006551001201	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1006551001202	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1006551001203	putative DNA binding site [nucleotide binding]; other site
1006551001204	putative Zn2+ binding site [ion binding]; other site
1006551001205	AsnC family; Region: AsnC_trans_reg; pfam01037
1006551001206	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
1006551001207	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1006551001208	Coenzyme A binding pocket [chemical binding]; other site
1006551001209	Uncharacterized conserved protein [Function unknown]; Region: COG3592
1006551001210	multidrug resistance protein MdtN; Provisional; Region: PRK10476
1006551001211	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1006551001212	HlyD family secretion protein; Region: HlyD_3; pfam13437
1006551001213	multidrug efflux system protein MdtO; Provisional; Region: PRK11427
1006551001214	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1006551001215	putative outer membrane efflux protein MdtP; Provisional; Region: PRK09915
1006551001216	ATP-dependent transcriptional regulator [Transcription]; Region: MalT; COG2909
1006551001217	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1006551001218	DNA binding residues [nucleotide binding]
1006551001219	dimerization interface [polypeptide binding]; other site
1006551001220	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1006551001221	acetoin reductases; Region: 23BDH; TIGR02415
1006551001222	NAD(P) binding site [chemical binding]; other site
1006551001223	active site
1006551001224	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551001225	putative substrate translocation pore; other site
1006551001226	POT family; Region: PTR2; cl17359
1006551001227	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
1006551001228	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1006551001229	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1006551001230	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1006551001231	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
1006551001232	D-xylulose kinases, subgroup 3; members of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_3; cd07811
1006551001233	putative N- and C-terminal domain interface [polypeptide binding]; other site
1006551001234	putative active site [active]
1006551001235	putative MgATP binding site [chemical binding]; other site
1006551001236	catalytic site [active]
1006551001237	metal binding site [ion binding]; metal-binding site
1006551001238	putative xylulose binding site [chemical binding]; other site
1006551001239	putative homodimer interface [polypeptide binding]; other site
1006551001240	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
1006551001241	intersubunit interface [polypeptide binding]; other site
1006551001242	active site
1006551001243	catalytic residue [active]
1006551001244	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1006551001245	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1006551001246	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1006551001247	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1006551001248	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1006551001249	hexamer interface [polypeptide binding]; other site
1006551001250	metal binding site [ion binding]; metal-binding site
1006551001251	substrate binding site [chemical binding]; other site
1006551001252	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1006551001253	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1006551001254	substrate binding site [chemical binding]; other site
1006551001255	dimer interface [polypeptide binding]; other site
1006551001256	ATP binding site [chemical binding]; other site
1006551001257	potential frameshift: common BLAST hit: gi|238894743|ref|YP_002919477.1| fucose permease
1006551001258	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1006551001259	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
1006551001260	active site
1006551001261	metal binding site [ion binding]; metal-binding site
1006551001262	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
1006551001263	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1006551001264	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_like_2; cd05917
1006551001265	acyl-activating enzyme (AAE) consensus motif; other site
1006551001266	acyl-activating enzyme (AAE) consensus motif; other site
1006551001267	putative AMP binding site [chemical binding]; other site
1006551001268	putative active site [active]
1006551001269	putative CoA binding site [chemical binding]; other site
1006551001270	Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670
1006551001271	Coenzyme A transferase; Region: CoA_trans; smart00882
1006551001272	Coenzyme A transferase; Region: CoA_trans; cl17247
1006551001273	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1006551001274	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1006551001275	NAD(P) binding site [chemical binding]; other site
1006551001276	active site
1006551001277	putative acyltransferase; Provisional; Region: PRK05790
1006551001278	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1006551001279	dimer interface [polypeptide binding]; other site
1006551001280	active site
1006551001281	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
1006551001282	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551001283	putative substrate translocation pore; other site
1006551001284	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
1006551001285	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551001286	putative substrate translocation pore; other site
1006551001287	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1006551001288	glycerate kinase; Region: TIGR00045
1006551001289	Sugar diacid utilization regulator [Transcription / Signal transduction mechanisms]; Region: CdaR; COG3835
1006551001290	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
1006551001291	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1006551001292	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551001293	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1006551001294	putative substrate translocation pore; other site
1006551001295	Predicted kinase [General function prediction only]; Region: COG0645
1006551001296	AAA domain; Region: AAA_17; pfam13207
1006551001297	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1006551001298	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
1006551001299	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551001300	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
1006551001301	dimerization interface [polypeptide binding]; other site
1006551001302	substrate binding pocket [chemical binding]; other site
1006551001303	A-factor biosynthesis hotdog domain; Region: AfsA; pfam03756
1006551001304	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235
1006551001305	active site 1 [active]
1006551001306	dimer interface [polypeptide binding]; other site
1006551001307	hexamer interface [polypeptide binding]; other site
1006551001308	active site 2 [active]
1006551001309	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
1006551001310	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1006551001311	motif II; other site
1006551001312	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1006551001313	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551001314	putative substrate translocation pore; other site
1006551001315	Carboxymuconolactone decarboxylase family; Region: CMD; cl00460
1006551001316	putative acyltransferase; Provisional; Region: PRK05790
1006551001317	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1006551001318	dimer interface [polypeptide binding]; other site
1006551001319	active site
1006551001320	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1006551001321	active site
1006551001322	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
1006551001323	Protein of unknown function (DUF987); Region: DUF987; pfam06174
1006551001324	hypothetical protein; Reviewed; Region: PRK00024
1006551001325	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1006551001326	MPN+ (JAMM) motif; other site
1006551001327	Zinc-binding site [ion binding]; other site
1006551001328	Antirestriction protein; Region: Antirestrict; pfam03230
1006551001329	Domain of unknown function (DUF932); Region: DUF932; pfam06067
1006551001330	Bacterial protein of unknown function (DUF905); Region: DUF905; pfam06006
1006551001331	SH3 domain-containing protein; Provisional; Region: PRK10884
1006551001332	Predicted transcriptional regulator [Transcription]; Region: COG2378
1006551001333	WYL domain; Region: WYL; pfam13280
1006551001334	Predicted GTPase [General function prediction only]; Region: COG3596
1006551001335	YfjP GTPase; Region: YfjP; cd11383
1006551001336	G1 box; other site
1006551001337	GTP/Mg2+ binding site [chemical binding]; other site
1006551001338	Switch I region; other site
1006551001339	G2 box; other site
1006551001340	Switch II region; other site
1006551001341	G3 box; other site
1006551001342	G4 box; other site
1006551001343	G5 box; other site
1006551001344	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
1006551001345	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
1006551001346	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
1006551001347	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551001348	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
1006551001349	putative substrate translocation pore; other site
1006551001350	Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer,  utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cl00514
1006551001351	FMN binding site [chemical binding]; other site
1006551001352	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
1006551001353	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1006551001354	active site
1006551001355	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1006551001356	catalytic tetrad [active]
1006551001357	heavy metal response regulator; Region: cztR_silR_copR; TIGR01387
1006551001358	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551001359	active site
1006551001360	phosphorylation site [posttranslational modification]
1006551001361	intermolecular recognition site; other site
1006551001362	dimerization interface [polypeptide binding]; other site
1006551001363	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1006551001364	DNA binding site [nucleotide binding]
1006551001365	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
1006551001366	HAMP domain; Region: HAMP; pfam00672
1006551001367	dimerization interface [polypeptide binding]; other site
1006551001368	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1006551001369	dimer interface [polypeptide binding]; other site
1006551001370	phosphorylation site [posttranslational modification]
1006551001371	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551001372	ATP binding site [chemical binding]; other site
1006551001373	Mg2+ binding site [ion binding]; other site
1006551001374	G-X-G motif; other site
1006551001375	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
1006551001376	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
1006551001377	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1006551001378	Uncharacterized enzymes similar to novel bacterial esterase that cleaves esters on halogenated cyclic compounds; Region: Esterase_713_like-3; cd12810
1006551001379	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1006551001380	catalytic site [active]
1006551001381	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1006551001382	putative acyl-acceptor binding pocket; other site
1006551001383	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1006551001384	Putative glucoamylase; Region: Glycoamylase; pfam10091
1006551001385	Second GH94N domain of cyclic beta 1-2 glucan synthetase and similar domains; Region: GH94N_ChvB_NdvB_2_like; cd11753
1006551001386	Cellobiose phosphorylase [Carbohydrate transport and metabolism]; Region: COG3459
1006551001387	First GH94N domain of cyclic beta 1-2 glucan synthetase and similar domains; Region: GH94N_ChvB_NdvB_1_like; cd11756
1006551001388	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1006551001389	DNA-binding site [nucleotide binding]; DNA binding site
1006551001390	RNA-binding motif; other site
1006551001391	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1006551001392	DNA-binding site [nucleotide binding]; DNA binding site
1006551001393	RNA-binding motif; other site
1006551001394	DNA binding protein, nucleoid-associated; Provisional; Region: PRK10328
1006551001395	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
1006551001396	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1006551001397	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1006551001398	active site
1006551001399	catalytic tetrad [active]
1006551001400	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1006551001401	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1006551001402	active site
1006551001403	catalytic tetrad [active]
1006551001404	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551001405	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551001406	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
1006551001407	putative effector binding pocket; other site
1006551001408	putative dimerization interface [polypeptide binding]; other site
1006551001409	atypical (a) SDRs, subgroup 5; Region: SDR_a5; cd05243
1006551001410	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1006551001411	NAD(P) binding site [chemical binding]; other site
1006551001412	putative active site [active]
1006551001413	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1006551001414	Protein of unknown function (DUF3644); Region: DUF3644; pfam12358
1006551001415	integrase; Provisional; Region: PRK09692
1006551001416	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1006551001417	active site
1006551001418	Int/Topo IB signature motif; other site
1006551001419	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1006551001420	Peptidase family M23; Region: Peptidase_M23; pfam01551
1006551001421	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551001422	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551001423	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1006551001424	dimerization interface [polypeptide binding]; other site
1006551001425	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; pfam01977
1006551001426	3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme metabolism]; Region: UbiX; COG0163
1006551001427	Flavoprotein; Region: Flavoprotein; pfam02441
1006551001428	Protein of unknown function (DUF554); Region: DUF554; pfam04474
1006551001429	Isopentenyldiphosphate isomerase [Lipid metabolism]; Region: Idi; COG1443
1006551001430	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
1006551001431	active site
1006551001432	metal binding site [ion binding]; metal-binding site
1006551001433	nudix motif; other site
1006551001434	lysyl-tRNA synthetase; Reviewed; Region: PRK12445
1006551001435	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1006551001436	dimer interface [polypeptide binding]; other site
1006551001437	putative anticodon binding site; other site
1006551001438	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1006551001439	motif 1; other site
1006551001440	active site
1006551001441	motif 2; other site
1006551001442	motif 3; other site
1006551001443	peptide chain release factor 2; Provisional; Region: PRK08787
1006551001444	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1006551001445	RF-1 domain; Region: RF-1; pfam00472
1006551001446	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
1006551001447	DHH family; Region: DHH; pfam01368
1006551001448	DHHA1 domain; Region: DHHA1; pfam02272
1006551001449	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
1006551001450	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
1006551001451	dimerization domain [polypeptide binding]; other site
1006551001452	dimer interface [polypeptide binding]; other site
1006551001453	catalytic residues [active]
1006551001454	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
1006551001455	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1006551001456	active site
1006551001457	Int/Topo IB signature motif; other site
1006551001458	flavodoxin FldB; Provisional; Region: PRK12359
1006551001459	Protein of unknown function (DUF1434); Region: DUF1434; pfam07254
1006551001460	hypothetical protein; Provisional; Region: PRK10878
1006551001461	putative global regulator; Reviewed; Region: PRK09559
1006551001462	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
1006551001463	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
1006551001464	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1006551001465	Walker A motif; other site
1006551001466	ATP binding site [chemical binding]; other site
1006551001467	Walker B motif; other site
1006551001468	arginine finger; other site
1006551001469	Transcriptional antiterminator [Transcription]; Region: COG3933
1006551001470	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
1006551001471	active site
1006551001472	active pocket/dimerization site; other site
1006551001473	phosphorylation site [posttranslational modification]
1006551001474	PRD domain; Region: PRD; pfam00874
1006551001475	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1006551001476	active pocket/dimerization site; other site
1006551001477	active site
1006551001478	phosphorylation site [posttranslational modification]
1006551001479	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1006551001480	active site
1006551001481	phosphorylation site [posttranslational modification]
1006551001482	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
1006551001483	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
1006551001484	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1006551001485	L-seryl-tRNA selenium transferase; Region: SelA; pfam03841
1006551001486	Protein of unknown function (DUF1341); Region: DUF1341; cl06211
1006551001487	hemolysin; Provisional; Region: PRK15087
1006551001488	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
1006551001489	ASC-1 homology domain, subfamily similar to Escherichia coli Yqfb. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as...; Region: ASCH_yqfb_like; cd06552
1006551001490	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1006551001491	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1006551001492	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1006551001493	putative active site [active]
1006551001494	6-phospho-beta-glucosidase BglA; Provisional; Region: PRK15014
1006551001495	beta-galactosidase; Region: BGL; TIGR03356
1006551001496	TlpA-like family, suppressor for copper sensitivity D protein (ScsD) and actinobacterial DsbE homolog subfamily; composed of ScsD, the DsbE homolog of Mycobacterium tuberculosis (MtbDsbE) and similar proteins, all containing a redox-active CXXC motif; Region: TlpA_like_ScsD_MtbDsbE; cd03011
1006551001497	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1006551001498	catalytic residues [active]
1006551001499	putative NAD(P)-binding oxidoreductase; Provisional; Region: PRK09730
1006551001500	classical (c) SDRs; Region: SDR_c; cd05233
1006551001501	NAD(P) binding site [chemical binding]; other site
1006551001502	active site
1006551001503	glycine dehydrogenase; Provisional; Region: PRK05367
1006551001504	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1006551001505	tetramer interface [polypeptide binding]; other site
1006551001506	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551001507	catalytic residue [active]
1006551001508	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1006551001509	tetramer interface [polypeptide binding]; other site
1006551001510	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551001511	catalytic residue [active]
1006551001512	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
1006551001513	lipoyl attachment site [posttranslational modification]; other site
1006551001514	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
1006551001515	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
1006551001516	oxidoreductase; Provisional; Region: PRK08013
1006551001517	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
1006551001518	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
1006551001519	2-polyprenyl-6-methoxyphenol 4-hydroxylase; Region: UbiH; TIGR01984
1006551001520	proline aminopeptidase P II; Provisional; Region: PRK10879
1006551001521	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
1006551001522	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
1006551001523	active site
1006551001524	hypothetical protein; Reviewed; Region: PRK01736
1006551001525	Z-ring-associated protein; Provisional; Region: PRK10972
1006551001526	5-formyltetrahydrofolate cyclo-ligase family protein; Provisional; Region: PRK10333
1006551001527	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
1006551001528	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
1006551001529	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
1006551001530	ligand binding site [chemical binding]; other site
1006551001531	NAD binding site [chemical binding]; other site
1006551001532	tetramer interface [polypeptide binding]; other site
1006551001533	catalytic site [active]
1006551001534	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
1006551001535	L-serine binding site [chemical binding]; other site
1006551001536	ACT domain interface; other site
1006551001537	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
1006551001538	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1006551001539	active site
1006551001540	dimer interface [polypeptide binding]; other site
1006551001541	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
1006551001542	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551001543	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
1006551001544	putative dimerization interface [polypeptide binding]; other site
1006551001545	methylmalonyl-CoA mutase; Reviewed; Region: PRK09426
1006551001546	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, Alpha subunit-like subfamily; contains proteins similar to the alpha subunit of Propionbacterium shermanni MCM, as well as human and E. coli MCM. Members of this subfamily contain...; Region: MM_CoA_mutase_alpha_like; cd03679
1006551001547	active site
1006551001548	substrate binding site [chemical binding]; other site
1006551001549	coenzyme B12 binding site [chemical binding]; other site
1006551001550	methylmalonyl CoA mutase B12 binding domain. This domain binds to B12 (adenosylcobamide), which initiates the conversion of succinyl CoA and methylmalonyl CoA by forming an adenosyl radical, which then undergoes a rearrangement exchanging a hydrogen atom...; Region: MM_CoA_mut_B12_BD; cd02071
1006551001551	B12 binding site [chemical binding]; other site
1006551001552	cobalt ligand [ion binding]; other site
1006551001553	membrane ATPase/protein kinase; Provisional; Region: PRK09435
1006551001554	The function of this protein family is unkown. The protein sequences are similar to the ArgK protein in E. coli. ArgK protein is a membrane ATPase which is required for transporting arginine, ornithine and lysine into the cells by the arginine and...; Region: ArgK-like; cd03114
1006551001555	Walker A; other site
1006551001556	methylmalonyl-CoA decarboxylase; Provisional; Region: PRK11423
1006551001557	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1006551001558	substrate binding site [chemical binding]; other site
1006551001559	oxyanion hole (OAH) forming residues; other site
1006551001560	trimer interface [polypeptide binding]; other site
1006551001561	succinate CoA transferase; Region: YgfH_subfam; TIGR03458
1006551001562	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
1006551001563	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
1006551001564	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551001565	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551001566	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1006551001567	dimerization interface [polypeptide binding]; other site
1006551001568	oxidative stress defense protein; Provisional; Region: PRK11087
1006551001569	Uncharacterized conserved protein [Function unknown]; Region: COG2968
1006551001570	arginine exporter protein; Provisional; Region: PRK09304
1006551001571	mechanosensitive channel MscS; Provisional; Region: PRK10334
1006551001572	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1006551001573	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1006551001574	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
1006551001575	active site
1006551001576	intersubunit interface [polypeptide binding]; other site
1006551001577	zinc binding site [ion binding]; other site
1006551001578	Na+ binding site [ion binding]; other site
1006551001579	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
1006551001580	Phosphoglycerate kinase; Region: PGK; pfam00162
1006551001581	substrate binding site [chemical binding]; other site
1006551001582	hinge regions; other site
1006551001583	ADP binding site [chemical binding]; other site
1006551001584	catalytic site [active]
1006551001585	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
1006551001586	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1006551001587	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1006551001588	Domain of unknown function found in archaea, bacteria, and plants; Region: DUF296; cd11378
1006551001589	trimer interface [polypeptide binding]; other site
1006551001590	putative Zn binding site [ion binding]; other site
1006551001591	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
1006551001592	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1006551001593	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1006551001594	Walker A/P-loop; other site
1006551001595	ATP binding site [chemical binding]; other site
1006551001596	Q-loop/lid; other site
1006551001597	ABC transporter signature motif; other site
1006551001598	Walker B; other site
1006551001599	D-loop; other site
1006551001600	H-loop/switch region; other site
1006551001601	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1006551001602	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1006551001603	Walker A/P-loop; other site
1006551001604	ATP binding site [chemical binding]; other site
1006551001605	Q-loop/lid; other site
1006551001606	ABC transporter signature motif; other site
1006551001607	Walker B; other site
1006551001608	D-loop; other site
1006551001609	H-loop/switch region; other site
1006551001610	transketolase; Reviewed; Region: PRK12753
1006551001611	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1006551001612	TPP-binding site [chemical binding]; other site
1006551001613	dimer interface [polypeptide binding]; other site
1006551001614	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1006551001615	PYR/PP interface [polypeptide binding]; other site
1006551001616	dimer interface [polypeptide binding]; other site
1006551001617	TPP binding site [chemical binding]; other site
1006551001618	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1006551001619	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
1006551001620	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
1006551001621	agmatinase; Region: agmatinase; TIGR01230
1006551001622	oligomer interface [polypeptide binding]; other site
1006551001623	putative active site [active]
1006551001624	Mn binding site [ion binding]; other site
1006551001625	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
1006551001626	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
1006551001627	dimer interface [polypeptide binding]; other site
1006551001628	active site
1006551001629	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1006551001630	catalytic residues [active]
1006551001631	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
1006551001632	Virulence promoting factor; Region: YqgB; pfam11036
1006551001633	Protein of unknown function (DUF2684); Region: DUF2684; pfam10885
1006551001634	S-adenosylmethionine synthetase; Validated; Region: PRK05250
1006551001635	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
1006551001636	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
1006551001637	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
1006551001638	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
1006551001639	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551001640	putative substrate translocation pore; other site
1006551001641	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551001642	hypothetical protein; Provisional; Region: PRK04860
1006551001643	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
1006551001644	DNA-specific endonuclease I; Provisional; Region: PRK15137
1006551001645	Endonuclease I [DNA replication, recombination, and repair]; Region: EndA; COG2356
1006551001646	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
1006551001647	RNA methyltransferase, RsmE family; Region: TIGR00046
1006551001648	glutathione synthetase; Provisional; Region: PRK05246
1006551001649	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
1006551001650	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
1006551001651	hypothetical protein; Validated; Region: PRK00228
1006551001652	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
1006551001653	DNA-binding transcriptional regulator CsgD; Provisional; Region: PRK10100
1006551001654	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1006551001655	DNA binding residues [nucleotide binding]
1006551001656	dimerization interface [polypeptide binding]; other site
1006551001657	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
1006551001658	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
1006551001659	Walker A motif; other site
1006551001660	ATP binding site [chemical binding]; other site
1006551001661	Walker B motif; other site
1006551001662	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
1006551001663	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1006551001664	catalytic residue [active]
1006551001665	YGGT family; Region: YGGT; pfam02325
1006551001666	Predicted integral membrane protein [Function unknown]; Region: COG0762
1006551001667	hypothetical protein; Validated; Region: PRK05090
1006551001668	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
1006551001669	active site
1006551001670	dimerization interface [polypeptide binding]; other site
1006551001671	HemN family oxidoreductase; Provisional; Region: PRK05660
1006551001672	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1006551001673	FeS/SAM binding site; other site
1006551001674	HemN C-terminal domain; Region: HemN_C; pfam06969
1006551001675	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
1006551001676	tripartite ATP-independent periplasmic transporter solute receptor, DctP family; Region: dctP; TIGR00787
1006551001677	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
1006551001678	DctM-like transporters; Region: DctM; pfam06808
1006551001679	TRAP transporter, DctM subunit; Region: dctM; TIGR00786
1006551001680	hypothetical protein; Provisional; Region: PRK10626
1006551001681	Protein of unknown function (DUF2884); Region: DUF2884; pfam11101
1006551001682	hypothetical protein; Provisional; Region: PRK11702
1006551001683	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
1006551001684	adenine DNA glycosylase; Provisional; Region: PRK10880
1006551001685	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1006551001686	minor groove reading motif; other site
1006551001687	helix-hairpin-helix signature motif; other site
1006551001688	substrate binding pocket [chemical binding]; other site
1006551001689	active site
1006551001690	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1006551001691	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
1006551001692	DNA binding and oxoG recognition site [nucleotide binding]
1006551001693	oxidative damage protection protein; Provisional; Region: PRK05408
1006551001694	murein transglycosylase C; Provisional; Region: mltC; PRK11671
1006551001695	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
1006551001696	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1006551001697	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1006551001698	catalytic residue [active]
1006551001699	nucleoside transporter; Region: 2A0110; TIGR00889
1006551001700	ornithine decarboxylase; Provisional; Region: PRK13578
1006551001701	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1006551001702	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1006551001703	homodimer interface [polypeptide binding]; other site
1006551001704	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551001705	catalytic residue [active]
1006551001706	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1006551001707	Protein of unknown function (DUF554); Region: DUF554; pfam04474
1006551001708	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1006551001709	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1006551001710	transmembrane helices; other site
1006551001711	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1006551001712	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1006551001713	dimer interface [polypeptide binding]; other site
1006551001714	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551001715	catalytic residue [active]
1006551001716	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the pyridoxal-phosphate (PALP) dependent enzyme domain upstream.   The vitamin B6 complex comprises pyridoxine, pyridoxal, and pyridoxamine, as well...; Region: CBS_pair_PALP_assoc2; cd04609
1006551001717	FOG: CBS domain [General function prediction only]; Region: COG0517
1006551001718	Cys/Met metabolism PLP-dependent enzyme; Region: Cys_Met_Meta_PP; pfam01053
1006551001719	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1006551001720	homodimer interface [polypeptide binding]; other site
1006551001721	substrate-cofactor binding pocket; other site
1006551001722	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551001723	catalytic residue [active]
1006551001724	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551001725	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551001726	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_8; cd08477
1006551001727	putative effector binding pocket; other site
1006551001728	putative dimerization interface [polypeptide binding]; other site
1006551001729	Lin1944 and related proteins, classical (c) SDRs; Region: Lin1944_like_SDR_c; cd11731
1006551001730	putative NAD(P) binding site [chemical binding]; other site
1006551001731	homodimer interface [polypeptide binding]; other site
1006551001732	Tyrosine phosphatase family; Region: Y_phosphatase3; pfam13350
1006551001733	Tyrosine phosphatase family C-terminal region; Region: Y_phosphatase3C; pfam13348
1006551001734	Autotransporter beta-domain; Region: Autotransporter; smart00869
1006551001735	Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436
1006551001736	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1006551001737	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551001738	homodimer interface [polypeptide binding]; other site
1006551001739	catalytic residue [active]
1006551001740	bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase; Provisional; Region: PRK10507
1006551001741	CHAP domain; Region: CHAP; pfam05257
1006551001742	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1006551001743	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1006551001744	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
1006551001745	Thioredoxin; Region: Thioredoxin_4; cl17273
1006551001746	putative S-transferase; Provisional; Region: PRK11752
1006551001747	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
1006551001748	C-terminal domain interface [polypeptide binding]; other site
1006551001749	GSH binding site (G-site) [chemical binding]; other site
1006551001750	dimer interface [polypeptide binding]; other site
1006551001751	C-terminal, alpha helical domain of Escherichia coli Yghu Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YghU_like; cd10292
1006551001752	dimer interface [polypeptide binding]; other site
1006551001753	N-terminal domain interface [polypeptide binding]; other site
1006551001754	active site
1006551001755	Protein of unknown function (DUF2623); Region: DUF2623; pfam11115
1006551001756	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
1006551001757	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1006551001758	hypothetical protein; Provisional; Region: PRK05208
1006551001759	biopolymer transport protein ExbD; Provisional; Region: PRK11267
1006551001760	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1006551001761	biopolymer transport protein ExbB; Provisional; Region: PRK10414
1006551001762	cystathionine beta-lyase; Provisional; Region: PRK08114
1006551001763	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1006551001764	homodimer interface [polypeptide binding]; other site
1006551001765	substrate-cofactor binding pocket; other site
1006551001766	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551001767	catalytic residue [active]
1006551001768	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1006551001769	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1006551001770	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
1006551001771	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1006551001772	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551001773	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551001774	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
1006551001775	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
1006551001776	dimer interface [polypeptide binding]; other site
1006551001777	active site
1006551001778	metal binding site [ion binding]; metal-binding site
1006551001779	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1006551001780	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1006551001781	active site
1006551001782	catalytic tetrad [active]
1006551001783	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537
1006551001784	nucleotide binding site/active site [active]
1006551001785	catalytic residue [active]
1006551001786	hypothetical protein; Provisional; Region: PRK01254
1006551001787	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
1006551001788	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
1006551001789	FtsI repressor; Provisional; Region: PRK10883
1006551001790	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1006551001791	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
1006551001792	1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018
1006551001793	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1006551001794	putative acyl-acceptor binding pocket; other site
1006551001795	DNA topoisomerase IV, A subunit, proteobacterial; Region: parC_Gneg; TIGR01062
1006551001796	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1006551001797	CAP-like domain; other site
1006551001798	active site
1006551001799	primary dimer interface [polypeptide binding]; other site
1006551001800	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1006551001801	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551001802	DNA gyrase inhibitor [DNA replication, recombination, and repair]; Region: COG3449
1006551001803	Periplasmic protein with OB-fold [Function unknown]; Region: COG3111
1006551001804	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
1006551001805	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551001806	active site
1006551001807	phosphorylation site [posttranslational modification]
1006551001808	intermolecular recognition site; other site
1006551001809	dimerization interface [polypeptide binding]; other site
1006551001810	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1006551001811	DNA binding site [nucleotide binding]
1006551001812	sensor protein QseC; Provisional; Region: PRK10337
1006551001813	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1006551001814	dimer interface [polypeptide binding]; other site
1006551001815	phosphorylation site [posttranslational modification]
1006551001816	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551001817	ATP binding site [chemical binding]; other site
1006551001818	Mg2+ binding site [ion binding]; other site
1006551001819	G-X-G motif; other site
1006551001820	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
1006551001821	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1006551001822	DNA topoisomerase IV, B subunit, proteobacterial; Region: parE_Gneg; TIGR01055
1006551001823	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551001824	ATP binding site [chemical binding]; other site
1006551001825	Mg2+ binding site [ion binding]; other site
1006551001826	G-X-G motif; other site
1006551001827	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1006551001828	anchoring element; other site
1006551001829	dimer interface [polypeptide binding]; other site
1006551001830	ATP binding site [chemical binding]; other site
1006551001831	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1006551001832	active site
1006551001833	metal binding site [ion binding]; metal-binding site
1006551001834	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1006551001835	esterase YqiA; Provisional; Region: PRK11071
1006551001836	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1006551001837	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
1006551001838	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1006551001839	active site
1006551001840	metal binding site [ion binding]; metal-binding site
1006551001841	hexamer interface [polypeptide binding]; other site
1006551001842	putative dehydrogenase; Provisional; Region: PRK11039
1006551001843	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
1006551001844	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1006551001845	dimer interface [polypeptide binding]; other site
1006551001846	ADP-ribose binding site [chemical binding]; other site
1006551001847	active site
1006551001848	nudix motif; other site
1006551001849	metal binding site [ion binding]; metal-binding site
1006551001850	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
1006551001851	hypothetical protein; Provisional; Region: PRK11653
1006551001852	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1006551001853	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
1006551001854	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
1006551001855	putative active site [active]
1006551001856	metal binding site [ion binding]; metal-binding site
1006551001857	zinc transporter ZupT; Provisional; Region: PRK04201
1006551001858	Fimbrial protein; Region: Fimbrial; cl01416
1006551001859	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1006551001860	PapC N-terminal domain; Region: PapC_N; pfam13954
1006551001861	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1006551001862	PapC C-terminal domain; Region: PapC_C; pfam13953
1006551001863	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1006551001864	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1006551001865	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1006551001866	Fimbrial protein; Region: Fimbrial; pfam00419
1006551001867	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
1006551001868	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
1006551001869	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960
1006551001870	Glycogen synthesis protein; Region: GlgS; cl11663
1006551001871	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
1006551001872	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
1006551001873	putative ribose interaction site [chemical binding]; other site
1006551001874	putative ADP binding site [chemical binding]; other site
1006551001875	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
1006551001876	active site
1006551001877	nucleotide binding site [chemical binding]; other site
1006551001878	HIGH motif; other site
1006551001879	KMSKS motif; other site
1006551001880	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
1006551001881	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1006551001882	metal binding triad; other site
1006551001883	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1006551001884	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1006551001885	metal binding triad; other site
1006551001886	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1006551001887	Uncharacterized conserved protein [Function unknown]; Region: COG3025
1006551001888	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
1006551001889	putative active site [active]
1006551001890	putative metal binding residues [ion binding]; other site
1006551001891	signature motif; other site
1006551001892	putative triphosphate binding site [ion binding]; other site
1006551001893	SH3 domain-containing protein; Provisional; Region: PRK10884
1006551001894	Bacterial SH3 domain homologues; Region: SH3b; smart00287
1006551001895	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
1006551001896	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1006551001897	active site
1006551001898	NTP binding site [chemical binding]; other site
1006551001899	metal binding triad [ion binding]; metal-binding site
1006551001900	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1006551001901	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1006551001902	Zn2+ binding site [ion binding]; other site
1006551001903	Mg2+ binding site [ion binding]; other site
1006551001904	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
1006551001905	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
1006551001906	homooctamer interface [polypeptide binding]; other site
1006551001907	active site
1006551001908	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
1006551001909	Urease accessory protein UreH [Posttranslational modification, protein turnover, chaperones]; Region: UreH; COG0829
1006551001910	Urease gamma-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use...; Region: Urease_gamma; cd00390
1006551001911	alpha-gamma subunit interface [polypeptide binding]; other site
1006551001912	beta-gamma subunit interface [polypeptide binding]; other site
1006551001913	Urease beta-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use of...; Region: Urease_beta; cd00407
1006551001914	gamma-beta subunit interface [polypeptide binding]; other site
1006551001915	alpha-beta subunit interface [polypeptide binding]; other site
1006551001916	urease subunit alpha; Reviewed; Region: ureC; PRK13207
1006551001917	Urease alpha-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, fungi and plants. Their primary role is to allow the use of...; Region: Urease_alpha; cd00375
1006551001918	subunit interactions [polypeptide binding]; other site
1006551001919	active site
1006551001920	flap region; other site
1006551001921	urease accessory protein UreE; Provisional; Region: ureE; PRK13261
1006551001922	UreE urease accessory protein. UreE is a metallochaperone assisting the insertion of a Ni2+ ion in the active site of urease, an important step in the in vivo assembly of urease, an enzyme that hydrolyses urea into ammonia and carbamic acid. The...; Region: UreE; cd00571
1006551001923	dimer interface [polypeptide binding]; other site
1006551001924	catalytic residues [active]
1006551001925	Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones]; Region: UreF; COG0830
1006551001926	UreF; Region: UreF; pfam01730
1006551001927	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1006551001928	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
1006551001929	UGMP family protein; Validated; Region: PRK09604
1006551001930	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
1006551001931	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
1006551001932	DNA primase; Validated; Region: dnaG; PRK05667
1006551001933	CHC2 zinc finger; Region: zf-CHC2; pfam01807
1006551001934	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1006551001935	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1006551001936	active site
1006551001937	metal binding site [ion binding]; metal-binding site
1006551001938	interdomain interaction site; other site
1006551001939	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
1006551001940	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
1006551001941	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
1006551001942	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
1006551001943	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1006551001944	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
1006551001945	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1006551001946	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1006551001947	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1006551001948	DNA binding residues [nucleotide binding]
1006551001949	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1006551001950	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1006551001951	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
1006551001952	active site
1006551001953	SUMO-1 interface [polypeptide binding]; other site
1006551001954	Domain of unknown function (DUF1889); Region: DUF1889; pfam08986
1006551001955	DNA-binding transcriptional regulator DhaR; Provisional; Region: PRK11388
1006551001956	PAS domain; Region: PAS; smart00091
1006551001957	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1006551001958	Walker A motif; other site
1006551001959	ATP binding site [chemical binding]; other site
1006551001960	Walker B motif; other site
1006551001961	arginine finger; other site
1006551001962	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1006551001963	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1006551001964	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
1006551001965	dimer interface [polypeptide binding]; other site
1006551001966	active site
1006551001967	metal binding site [ion binding]; metal-binding site
1006551001968	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK11468
1006551001969	Dak1 domain; Region: Dak1; pfam02733
1006551001970	dihydroxyacetone kinase subunit DhaL; Provisional; Region: PRK10005
1006551001971	dihydroxyacetone kinase subunit M; Provisional; Region: PRK11377
1006551001972	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3412
1006551001973	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1006551001974	regulatory protein interface [polypeptide binding]; other site
1006551001975	active site
1006551001976	regulatory phosphorylation site [posttranslational modification]; other site
1006551001977	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1006551001978	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1006551001979	potential frameshift: common BLAST hit: gi|288933485|ref|YP_003437544.1| dihydroxyacetone kinase
1006551001980	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
1006551001981	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
1006551001982	FAD binding pocket [chemical binding]; other site
1006551001983	FAD binding motif [chemical binding]; other site
1006551001984	phosphate binding motif [ion binding]; other site
1006551001985	NAD binding pocket [chemical binding]; other site
1006551001986	Predicted transcriptional regulators [Transcription]; Region: COG1695
1006551001987	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1006551001988	putrescine--2-oxoglutarate aminotransferase; Provisional; Region: PRK11522
1006551001989	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1006551001990	inhibitor-cofactor binding pocket; inhibition site
1006551001991	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551001992	catalytic residue [active]
1006551001993	tRNA-binding-domain-containing CsaA-like proteins. CsaA is a molecular chaperone with export related activities. CsaA has a putative tRNA binding activity. The functional unit of CsaA is a homodimer and this domain acts as a dimerization domain; Region: tRNA_bind_CsaA; cd02798
1006551001994	dimer interface [polypeptide binding]; other site
1006551001995	putative tRNA-binding site [nucleotide binding]; other site
1006551001996	DNA-binding transcriptional repressor EbgR; Provisional; Region: PRK10339
1006551001997	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1006551001998	DNA binding site [nucleotide binding]
1006551001999	Ligand-binding domain of DNA transcription repressor GalR which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalR; cd01544
1006551002000	putative dimerization interface [polypeptide binding]; other site
1006551002001	putative ligand binding site [chemical binding]; other site
1006551002002	cryptic beta-D-galactosidase subunit alpha; Reviewed; Region: ebgA; PRK10340
1006551002003	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1006551002004	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1006551002005	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1006551002006	Beta galactosidase small chain; Region: Bgal_small_N; smart01038
1006551002007	Domain of unknown function (DUF386); Region: DUF386; cl01047
1006551002008	inner membrane transporter YjeM; Provisional; Region: PRK15238
1006551002009	inner membrane transporter YjeM; Provisional; Region: PRK15238
1006551002010	alpha-glucosidase; Provisional; Region: PRK10137
1006551002011	Protein of unknown function, DUF608; Region: DUF608; pfam04685
1006551002012	Trehalase; Region: Trehalase; cl17346
1006551002013	autoinducer-2 (AI-2) modifying protein LsrG; Provisional; Region: PRK10486
1006551002014	DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes [Carbohydrate transport and metabolism]; Region: FbaB; COG1830
1006551002015	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
1006551002016	putative active site; other site
1006551002017	catalytic residue [active]
1006551002018	autoinducer 2-binding protein lsrB; Provisional; Region: PRK15408
1006551002019	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
1006551002020	ligand binding site [chemical binding]; other site
1006551002021	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1006551002022	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1006551002023	TM-ABC transporter signature motif; other site
1006551002024	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1006551002025	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1006551002026	TM-ABC transporter signature motif; other site
1006551002027	autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional; Region: PRK15439
1006551002028	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1006551002029	Walker A/P-loop; other site
1006551002030	ATP binding site [chemical binding]; other site
1006551002031	Q-loop/lid; other site
1006551002032	ABC transporter signature motif; other site
1006551002033	Walker B; other site
1006551002034	D-loop; other site
1006551002035	H-loop/switch region; other site
1006551002036	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1006551002037	transcriptional regulator LsrR; Provisional; Region: PRK15418
1006551002038	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
1006551002039	autoinducer-2 (AI-2) kinase; Provisional; Region: PRK10939
1006551002040	Autoinducer-2 kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_AI-2K; cd07775
1006551002041	putative N- and C-terminal domain interface [polypeptide binding]; other site
1006551002042	putative active site [active]
1006551002043	putative MgATP binding site [chemical binding]; other site
1006551002044	catalytic site [active]
1006551002045	metal binding site [ion binding]; metal-binding site
1006551002046	putative carbohydrate binding site [chemical binding]; other site
1006551002047	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1006551002048	2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli  is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930
1006551002049	active site
1006551002050	FMN binding site [chemical binding]; other site
1006551002051	2,4-decadienoyl-CoA binding site; other site
1006551002052	catalytic residue [active]
1006551002053	4Fe-4S cluster binding site [ion binding]; other site
1006551002054	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
1006551002055	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1006551002056	SAM-dependent 23S ribosomal RNA mG1835 methyltransferase; Provisional; Region: PRK15001
1006551002057	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551002058	S-adenosylmethionine binding site [chemical binding]; other site
1006551002059	putative symporter YagG; Provisional; Region: PRK09669
1006551002060	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1006551002061	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551002062	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1006551002063	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551002064	Beta-xylosidase [Carbohydrate transport and metabolism]; Region: XynB; COG3507
1006551002065	Glycosyl hydrolase family 43, beta-D-xylosidase; Region: GH43_XYL_1; cd09000
1006551002066	inhibitor binding site; inhibition site
1006551002067	active site
1006551002068	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
1006551002069	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1006551002070	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1006551002071	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
1006551002072	serine/threonine transporter SstT; Provisional; Region: PRK13628
1006551002073	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1006551002074	Bacterial inner membrane protein; Region: Imp-YgjV; pfam10688
1006551002075	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
1006551002076	galactarate dehydratase; Region: galactar-dH20; TIGR03248
1006551002077	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
1006551002078	Glucuronate isomerase; Region: UxaC; pfam02614
1006551002079	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
1006551002080	D-galactonate transporter; Region: 2A0114; TIGR00893
1006551002081	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551002082	putative substrate translocation pore; other site
1006551002083	DNA-binding transcriptional repressor ExuR; Provisional; Region: PRK11523
1006551002084	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551002085	DNA-binding site [nucleotide binding]; DNA binding site
1006551002086	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1006551002087	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1006551002088	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1006551002089	EnvZ/OmpR regulon moderator; Provisional; Region: PRK10629
1006551002090	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
1006551002091	Uncharacterized conserved protein [Function unknown]; Region: ElaB; COG4575
1006551002092	Predicted membrane protein [Function unknown]; Region: COG5393
1006551002093	YqjK-like protein; Region: YqjK; pfam13997
1006551002094	Predicted membrane protein [Function unknown]; Region: COG2259
1006551002095	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
1006551002096	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
1006551002097	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
1006551002098	putative dimer interface [polypeptide binding]; other site
1006551002099	N-terminal domain interface [polypeptide binding]; other site
1006551002100	putative substrate binding pocket (H-site) [chemical binding]; other site
1006551002101	Predicted membrane protein [Function unknown]; Region: COG3152
1006551002102	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551002103	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1006551002104	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1006551002105	dimerization interface [polypeptide binding]; other site
1006551002106	Pirin-related protein [General function prediction only]; Region: COG1741
1006551002107	Pirin; Region: Pirin; pfam02678
1006551002108	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1006551002109	dimer interface [polypeptide binding]; other site
1006551002110	Glycerate kinase family; Region: Gly_kinase; cl00841
1006551002111	tartronate semialdehyde reductase; Provisional; Region: garR; PRK11559
1006551002112	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1006551002113	alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional; Region: PRK10558
1006551002114	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551002115	D-galactonate transporter; Region: 2A0114; TIGR00893
1006551002116	putative substrate translocation pore; other site
1006551002117	galactarate dehydratase; Region: galactar-dH20; TIGR03248
1006551002118	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
1006551002119	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
1006551002120	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1006551002121	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1006551002122	substrate binding site [chemical binding]; other site
1006551002123	ATP binding site [chemical binding]; other site
1006551002124	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1006551002125	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1006551002126	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1006551002127	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1006551002128	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1006551002129	intersubunit interface [polypeptide binding]; other site
1006551002130	active site
1006551002131	zinc binding site [ion binding]; other site
1006551002132	Na+ binding site [ion binding]; other site
1006551002133	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
1006551002134	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1006551002135	putative substrate binding site [chemical binding]; other site
1006551002136	putative ATP binding site [chemical binding]; other site
1006551002137	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1006551002138	active site
1006551002139	P-loop; other site
1006551002140	phosphorylation site [posttranslational modification]
1006551002141	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1006551002142	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1006551002143	active site
1006551002144	phosphorylation site [posttranslational modification]
1006551002145	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1006551002146	dimerization domain swap beta strand [polypeptide binding]; other site
1006551002147	regulatory protein interface [polypeptide binding]; other site
1006551002148	active site
1006551002149	regulatory phosphorylation site [posttranslational modification]; other site
1006551002150	D-tagatose-1,6-bisphosphate aldolase subunit GatZ; Provisional; Region: PRK15052
1006551002151	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1006551002152	active site
1006551002153	phosphorylation site [posttranslational modification]
1006551002154	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
1006551002155	active site
1006551002156	P-loop; other site
1006551002157	phosphorylation site [posttranslational modification]
1006551002158	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
1006551002159	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
1006551002160	galactitol-1-phosphate dehydrogenase; Provisional; Region: PRK10309
1006551002161	NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236
1006551002162	putative NAD(P) binding site [chemical binding]; other site
1006551002163	catalytic Zn binding site [ion binding]; other site
1006551002164	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1006551002165	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1006551002166	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1006551002167	Fic family protein [Function unknown]; Region: COG3177
1006551002168	Fic/DOC family; Region: Fic; pfam02661
1006551002169	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
1006551002170	SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994
1006551002171	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1006551002172	putative SAM binding site [chemical binding]; other site
1006551002173	putative homodimer interface [polypeptide binding]; other site
1006551002174	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1006551002175	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
1006551002176	putative ligand binding site [chemical binding]; other site
1006551002177	hypothetical protein; Reviewed; Region: PRK12497
1006551002178	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1006551002179	dimer interface [polypeptide binding]; other site
1006551002180	active site
1006551002181	outer membrane lipoprotein; Provisional; Region: PRK11023
1006551002182	BON domain; Region: BON; pfam04972
1006551002183	BON domain; Region: BON; pfam04972
1006551002184	Predicted permease; Region: DUF318; pfam03773
1006551002185	CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250
1006551002186	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1006551002187	NAD binding site [chemical binding]; other site
1006551002188	active site
1006551002189	intracellular protease, PfpI family; Region: PfpI; TIGR01382
1006551002190	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
1006551002191	proposed catalytic triad [active]
1006551002192	conserved cys residue [active]
1006551002193	hypothetical protein; Provisional; Region: PRK03467
1006551002194	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
1006551002195	GIY-YIG motif/motif A; other site
1006551002196	putative active site [active]
1006551002197	putative metal binding site [ion binding]; other site
1006551002198	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
1006551002199	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1006551002200	Coenzyme A binding pocket [chemical binding]; other site
1006551002201	Putative lipid carrier protein [Lipid metabolism]; Region: COG3154
1006551002202	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1006551002203	Peptidase family U32; Region: Peptidase_U32; pfam01136
1006551002204	putative protease; Provisional; Region: PRK15447
1006551002205	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1006551002206	hypothetical protein; Provisional; Region: PRK10508
1006551002207	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
1006551002208	tryptophan permease; Provisional; Region: PRK10483
1006551002209	aromatic amino acid transport protein; Region: araaP; TIGR00837
1006551002210	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
1006551002211	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1006551002212	ATP binding site [chemical binding]; other site
1006551002213	Mg++ binding site [ion binding]; other site
1006551002214	motif III; other site
1006551002215	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1006551002216	nucleotide binding region [chemical binding]; other site
1006551002217	ATP-binding site [chemical binding]; other site
1006551002218	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
1006551002219	putative RNA binding site [nucleotide binding]; other site
1006551002220	lipoprotein NlpI; Provisional; Region: PRK11189
1006551002221	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1006551002222	binding surface
1006551002223	TPR motif; other site
1006551002224	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
1006551002225	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
1006551002226	RNase E interface [polypeptide binding]; other site
1006551002227	trimer interface [polypeptide binding]; other site
1006551002228	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
1006551002229	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
1006551002230	RNase E interface [polypeptide binding]; other site
1006551002231	trimer interface [polypeptide binding]; other site
1006551002232	active site
1006551002233	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
1006551002234	putative nucleic acid binding region [nucleotide binding]; other site
1006551002235	G-X-X-G motif; other site
1006551002236	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
1006551002237	RNA binding site [nucleotide binding]; other site
1006551002238	domain interface; other site
1006551002239	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1006551002240	16S/18S rRNA binding site [nucleotide binding]; other site
1006551002241	S13e-L30e interaction site [polypeptide binding]; other site
1006551002242	25S rRNA binding site [nucleotide binding]; other site
1006551002243	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
1006551002244	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
1006551002245	RNA binding site [nucleotide binding]; other site
1006551002246	active site
1006551002247	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
1006551002248	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
1006551002249	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1006551002250	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
1006551002251	translation initiation factor IF-2; Region: IF-2; TIGR00487
1006551002252	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1006551002253	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1006551002254	G1 box; other site
1006551002255	putative GEF interaction site [polypeptide binding]; other site
1006551002256	GTP/Mg2+ binding site [chemical binding]; other site
1006551002257	Switch I region; other site
1006551002258	G2 box; other site
1006551002259	G3 box; other site
1006551002260	Switch II region; other site
1006551002261	G4 box; other site
1006551002262	G5 box; other site
1006551002263	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1006551002264	Translation-initiation factor 2; Region: IF-2; pfam11987
1006551002265	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1006551002266	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
1006551002267	NusA N-terminal domain; Region: NusA_N; pfam08529
1006551002268	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
1006551002269	RNA binding site [nucleotide binding]; other site
1006551002270	homodimer interface [polypeptide binding]; other site
1006551002271	NusA-like KH domain; Region: KH_5; pfam13184
1006551002272	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1006551002273	G-X-X-G motif; other site
1006551002274	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1006551002275	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1006551002276	ribosome maturation protein RimP; Reviewed; Region: PRK00092
1006551002277	Sm and related proteins; Region: Sm_like; cl00259
1006551002278	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
1006551002279	putative oligomer interface [polypeptide binding]; other site
1006551002280	putative RNA binding site [nucleotide binding]; other site
1006551002281	argininosuccinate synthase; Validated; Region: PRK05370
1006551002282	argininosuccinate synthase; Provisional; Region: PRK13820
1006551002283	Preprotein translocase SecG subunit; Region: SecG; pfam03840
1006551002284	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
1006551002285	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
1006551002286	active site
1006551002287	substrate binding site [chemical binding]; other site
1006551002288	metal binding site [ion binding]; metal-binding site
1006551002289	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1006551002290	dihydropteroate synthase; Region: DHPS; TIGR01496
1006551002291	substrate binding pocket [chemical binding]; other site
1006551002292	dimer interface [polypeptide binding]; other site
1006551002293	inhibitor binding site; inhibition site
1006551002294	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
1006551002295	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1006551002296	Walker A motif; other site
1006551002297	ATP binding site [chemical binding]; other site
1006551002298	Walker B motif; other site
1006551002299	arginine finger; other site
1006551002300	Peptidase family M41; Region: Peptidase_M41; pfam01434
1006551002301	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
1006551002302	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551002303	S-adenosylmethionine binding site [chemical binding]; other site
1006551002304	RNA-binding protein YhbY; Provisional; Region: PRK10343
1006551002305	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1006551002306	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1006551002307	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1006551002308	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
1006551002309	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
1006551002310	GTPase CgtA; Reviewed; Region: obgE; PRK12298
1006551002311	GTP1/OBG; Region: GTP1_OBG; pfam01018
1006551002312	Obg GTPase; Region: Obg; cd01898
1006551002313	G1 box; other site
1006551002314	GTP/Mg2+ binding site [chemical binding]; other site
1006551002315	Switch I region; other site
1006551002316	G2 box; other site
1006551002317	G3 box; other site
1006551002318	Switch II region; other site
1006551002319	G4 box; other site
1006551002320	G5 box; other site
1006551002321	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1006551002322	EamA-like transporter family; Region: EamA; pfam00892
1006551002323	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1006551002324	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
1006551002325	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
1006551002326	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1006551002327	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1006551002328	substrate binding pocket [chemical binding]; other site
1006551002329	chain length determination region; other site
1006551002330	substrate-Mg2+ binding site; other site
1006551002331	catalytic residues [active]
1006551002332	aspartate-rich region 1; other site
1006551002333	active site lid residues [active]
1006551002334	aspartate-rich region 2; other site
1006551002335	DNA-binding transcriptional regulator Nlp; Provisional; Region: PRK10344
1006551002336	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1006551002337	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1006551002338	hinge; other site
1006551002339	active site
1006551002340	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
1006551002341	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
1006551002342	anti sigma factor interaction site; other site
1006551002343	regulatory phosphorylation site [posttranslational modification]; other site
1006551002344	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
1006551002345	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
1006551002346	mce related protein; Region: MCE; pfam02470
1006551002347	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
1006551002348	conserved hypothetical integral membrane protein; Region: TIGR00056
1006551002349	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
1006551002350	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
1006551002351	Walker A/P-loop; other site
1006551002352	ATP binding site [chemical binding]; other site
1006551002353	Q-loop/lid; other site
1006551002354	ABC transporter signature motif; other site
1006551002355	Walker B; other site
1006551002356	D-loop; other site
1006551002357	H-loop/switch region; other site
1006551002358	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
1006551002359	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1006551002360	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1006551002361	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
1006551002362	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1006551002363	putative active site [active]
1006551002364	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1006551002365	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
1006551002366	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
1006551002367	lipopolysaccharide exporter periplasmic protein; Provisional; Region: PRK10893
1006551002368	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
1006551002369	OstA-like protein; Region: OstA; cl00844
1006551002370	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
1006551002371	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
1006551002372	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
1006551002373	Walker A/P-loop; other site
1006551002374	ATP binding site [chemical binding]; other site
1006551002375	Q-loop/lid; other site
1006551002376	ABC transporter signature motif; other site
1006551002377	Walker B; other site
1006551002378	D-loop; other site
1006551002379	H-loop/switch region; other site
1006551002380	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
1006551002381	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
1006551002382	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
1006551002383	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
1006551002384	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1006551002385	30S subunit binding site; other site
1006551002386	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1006551002387	active site
1006551002388	phosphorylation site [posttranslational modification]
1006551002389	P-loop ATPase protein family; Region: ATP_bind_2; pfam03668
1006551002390	AAA domain; Region: AAA_18; pfam13238
1006551002391	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1006551002392	dimerization domain swap beta strand [polypeptide binding]; other site
1006551002393	regulatory protein interface [polypeptide binding]; other site
1006551002394	active site
1006551002395	regulatory phosphorylation site [posttranslational modification]; other site
1006551002396	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
1006551002397	Transglycosylase; Region: Transgly; cl17702
1006551002398	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
1006551002399	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
1006551002400	conserved cys residue [active]
1006551002401	aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091
1006551002402	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1006551002403	putative active site [active]
1006551002404	heme pocket [chemical binding]; other site
1006551002405	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1006551002406	dimer interface [polypeptide binding]; other site
1006551002407	phosphorylation site [posttranslational modification]
1006551002408	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551002409	ATP binding site [chemical binding]; other site
1006551002410	Mg2+ binding site [ion binding]; other site
1006551002411	G-X-G motif; other site
1006551002412	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551002413	active site
1006551002414	phosphorylation site [posttranslational modification]
1006551002415	intermolecular recognition site; other site
1006551002416	dimerization interface [polypeptide binding]; other site
1006551002417	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1006551002418	putative binding surface; other site
1006551002419	active site
1006551002420	radical SAM protein, TIGR01212 family; Region: TIGR01212
1006551002421	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1006551002422	FeS/SAM binding site; other site
1006551002423	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
1006551002424	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
1006551002425	active site
1006551002426	dimer interface [polypeptide binding]; other site
1006551002427	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
1006551002428	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
1006551002429	active site
1006551002430	FMN binding site [chemical binding]; other site
1006551002431	substrate binding site [chemical binding]; other site
1006551002432	3Fe-4S cluster binding site [ion binding]; other site
1006551002433	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
1006551002434	domain interface; other site
1006551002435	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
1006551002436	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1006551002437	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1006551002438	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1006551002439	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1006551002440	N-acetylmannosamine kinase; Provisional; Region: PRK05082
1006551002441	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1006551002442	nucleotide binding site [chemical binding]; other site
1006551002443	Putative N-acetylmannosamine-6-phosphate epimerase [Carbohydrate transport and metabolism]; Region: NanE; COG3010
1006551002444	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
1006551002445	putative active site cavity [active]
1006551002446	putative sialic acid transporter; Provisional; Region: PRK03893
1006551002447	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551002448	putative substrate translocation pore; other site
1006551002449	N-acetylneuraminate lyase; Provisional; Region: PRK04147
1006551002450	N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); Region: NAL; cd00954
1006551002451	inhibitor site; inhibition site
1006551002452	active site
1006551002453	dimer interface [polypeptide binding]; other site
1006551002454	catalytic residue [active]
1006551002455	transcriptional regulator NanR; Provisional; Region: PRK03837
1006551002456	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551002457	DNA-binding site [nucleotide binding]; DNA binding site
1006551002458	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1006551002459	ClpXP protease specificity-enhancing factor; Provisional; Region: PRK11798
1006551002460	stringent starvation protein A; Provisional; Region: sspA; PRK09481
1006551002461	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
1006551002462	C-terminal domain interface [polypeptide binding]; other site
1006551002463	putative GSH binding site (G-site) [chemical binding]; other site
1006551002464	dimer interface [polypeptide binding]; other site
1006551002465	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
1006551002466	dimer interface [polypeptide binding]; other site
1006551002467	N-terminal domain interface [polypeptide binding]; other site
1006551002468	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1006551002469	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1006551002470	23S rRNA interface [nucleotide binding]; other site
1006551002471	L3 interface [polypeptide binding]; other site
1006551002472	Predicted ATPase [General function prediction only]; Region: COG1485
1006551002473	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105
1006551002474	hypothetical protein; Provisional; Region: PRK11677
1006551002475	serine endoprotease; Provisional; Region: PRK10139
1006551002476	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1006551002477	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1006551002478	protein binding site [polypeptide binding]; other site
1006551002479	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1006551002480	serine endoprotease; Provisional; Region: PRK10898
1006551002481	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1006551002482	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1006551002483	protein binding site [polypeptide binding]; other site
1006551002484	Triphosphoribosyl-dephospho-CoA synthetase [Coenzyme metabolism]; Region: CitG; COG1767
1006551002485	oxaloacetate decarboxylase subunit beta; Provisional; Region: PRK15476
1006551002486	Pyruvate/oxaloacetate carboxyltransferase [Energy production and conversion]; Region: COG5016
1006551002487	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
1006551002488	active site
1006551002489	metal binding site [ion binding]; metal-binding site
1006551002490	homodimer binding site [polypeptide binding]; other site
1006551002491	potential protein location (hypothetical protein) that overlaps protein (oxaloacetate decarboxylase)
1006551002492	oxaloacetate decarboxylase subunit gamma; Provisional; Region: PRK02919
1006551002493	L(+)-tartrate dehydratase subunit beta; Validated; Region: PRK08228
1006551002494	tartrate dehydratase subunit alpha; Validated; Region: PRK08230
1006551002495	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1006551002496	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1006551002497	transmembrane helices; other site
1006551002498	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1006551002499	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551002500	DNA-binding site [nucleotide binding]; DNA binding site
1006551002501	FCD domain; Region: FCD; pfam07729
1006551002502	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1006551002503	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551002504	DNA-binding site [nucleotide binding]; DNA binding site
1006551002505	malate dehydrogenase; Provisional; Region: PRK05086
1006551002506	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
1006551002507	NAD binding site [chemical binding]; other site
1006551002508	dimerization interface [polypeptide binding]; other site
1006551002509	Substrate binding site [chemical binding]; other site
1006551002510	arginine repressor; Provisional; Region: PRK05066
1006551002511	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
1006551002512	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
1006551002513	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1006551002514	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1006551002515	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it, thus inhibiting its potentially lethal RNase activity inside the...; Region: Barstar_like; cl01048
1006551002516	RNAase interaction site [polypeptide binding]; other site
1006551002517	p-hydroxybenzoic acid efflux subunit AaeB; Provisional; Region: PRK10631
1006551002518	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1006551002519	p-hydroxybenzoic acid efflux subunit AaeA; Provisional; Region: PRK10559
1006551002520	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1006551002521	HlyD family secretion protein; Region: HlyD_3; pfam13437
1006551002522	efflux system membrane protein; Provisional; Region: PRK11594
1006551002523	transcriptional regulator; Provisional; Region: PRK10632
1006551002524	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551002525	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1006551002526	putative effector binding pocket; other site
1006551002527	dimerization interface [polypeptide binding]; other site
1006551002528	DNA-binding transcriptional activator FucR; Provisional; Region: PRK10411
1006551002529	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1006551002530	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1006551002531	protease TldD; Provisional; Region: tldD; PRK10735
1006551002532	hypothetical protein; Provisional; Region: PRK10899
1006551002533	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1006551002534	ribonuclease G; Provisional; Region: PRK11712
1006551002535	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1006551002536	homodimer interface [polypeptide binding]; other site
1006551002537	oligonucleotide binding site [chemical binding]; other site
1006551002538	Maf-like protein; Region: Maf; pfam02545
1006551002539	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1006551002540	active site
1006551002541	dimer interface [polypeptide binding]; other site
1006551002542	rod shape-determining protein MreD; Provisional; Region: PRK11060
1006551002543	rod shape-determining protein MreC; Region: mreC; TIGR00219
1006551002544	rod shape-determining protein MreC; Region: MreC; pfam04085
1006551002545	rod shape-determining protein MreB; Provisional; Region: PRK13927
1006551002546	MreB and similar proteins; Region: MreB_like; cd10225
1006551002547	nucleotide binding site [chemical binding]; other site
1006551002548	Mg binding site [ion binding]; other site
1006551002549	putative protofilament interaction site [polypeptide binding]; other site
1006551002550	RodZ interaction site [polypeptide binding]; other site
1006551002551	regulatory protein CsrD; Provisional; Region: PRK11059
1006551002552	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1006551002553	metal binding site [ion binding]; metal-binding site
1006551002554	active site
1006551002555	I-site; other site
1006551002556	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1006551002557	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
1006551002558	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
1006551002559	NADP binding site [chemical binding]; other site
1006551002560	dimer interface [polypeptide binding]; other site
1006551002561	TMAO/DMSO reductase; Reviewed; Region: PRK05363
1006551002562	YedY_like molybdopterin cofactor (Moco) binding domain, a subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. Escherichia coli YedY has been propsed to form a heterodimer, consisting of a soluble catalytic subunit termed YedY; Region: YedY_like_Moco; cd02107
1006551002563	Moco binding site; other site
1006551002564	metal coordination site [ion binding]; other site
1006551002565	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
1006551002566	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
1006551002567	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1006551002568	carboxyltransferase (CT) interaction site; other site
1006551002569	biotinylation site [posttranslational modification]; other site
1006551002570	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
1006551002571	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1006551002572	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1006551002573	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1006551002574	hypothetical protein; Provisional; Region: PRK10633
1006551002575	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
1006551002576	Na binding site [ion binding]; other site
1006551002577	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
1006551002578	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1006551002579	Carbonic anhydrase alpha, prokaryotic-like subfamily. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon...; Region: alpha_CA_prokaryotic_like; cd03124
1006551002580	active site
1006551002581	zinc binding site [ion binding]; other site
1006551002582	tRNA-dihydrouridine synthase B; Provisional; Region: PRK10415
1006551002583	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1006551002584	FMN binding site [chemical binding]; other site
1006551002585	active site
1006551002586	catalytic residues [active]
1006551002587	substrate binding site [chemical binding]; other site
1006551002588	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
1006551002589	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
1006551002590	DNA-binding transcriptional regulator EnvR; Provisional; Region: PRK09975
1006551002591	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1006551002592	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
1006551002593	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
1006551002594	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1006551002595	HlyD family secretion protein; Region: HlyD_3; pfam13437
1006551002596	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
1006551002597	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
1006551002598	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
1006551002599	trimer interface [polypeptide binding]; other site
1006551002600	putative metal binding site [ion binding]; other site
1006551002601	Protein of unknown function (DUF1488); Region: DUF1488; pfam07369
1006551002602	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
1006551002603	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1006551002604	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1006551002605	shikimate binding site; other site
1006551002606	NAD(P) binding site [chemical binding]; other site
1006551002607	tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Provisional; Region: PRK10634
1006551002608	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1006551002609	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
1006551002610	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1006551002611	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1006551002612	hypothetical protein; Validated; Region: PRK03430
1006551002613	hypothetical protein; Provisional; Region: PRK10736
1006551002614	DNA protecting protein DprA; Region: dprA; TIGR00732
1006551002615	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1006551002616	active site
1006551002617	catalytic residues [active]
1006551002618	metal binding site [ion binding]; metal-binding site
1006551002619	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
1006551002620	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
1006551002621	putative active site [active]
1006551002622	substrate binding site [chemical binding]; other site
1006551002623	putative cosubstrate binding site; other site
1006551002624	catalytic site [active]
1006551002625	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1006551002626	substrate binding site [chemical binding]; other site
1006551002627	16S rRNA methyltransferase B; Provisional; Region: PRK10901
1006551002628	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
1006551002629	putative RNA binding site [nucleotide binding]; other site
1006551002630	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551002631	S-adenosylmethionine binding site [chemical binding]; other site
1006551002632	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
1006551002633	TrkA-N domain; Region: TrkA_N; pfam02254
1006551002634	TrkA-C domain; Region: TrkA_C; pfam02080
1006551002635	TrkA-N domain; Region: TrkA_N; pfam02254
1006551002636	TrkA-C domain; Region: TrkA_C; pfam02080
1006551002637	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
1006551002638	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
1006551002639	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3036
1006551002640	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
1006551002641	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
1006551002642	DNA binding residues [nucleotide binding]
1006551002643	dimer interface [polypeptide binding]; other site
1006551002644	metal binding site [ion binding]; metal-binding site
1006551002645	hypothetical protein; Provisional; Region: PRK10203
1006551002646	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
1006551002647	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
1006551002648	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1006551002649	alphaNTD homodimer interface [polypeptide binding]; other site
1006551002650	alphaNTD - beta interaction site [polypeptide binding]; other site
1006551002651	alphaNTD - beta' interaction site [polypeptide binding]; other site
1006551002652	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1006551002653	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1006551002654	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1006551002655	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1006551002656	RNA binding surface [nucleotide binding]; other site
1006551002657	30S ribosomal protein S11; Validated; Region: PRK05309
1006551002658	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
1006551002659	30S ribosomal protein S13; Region: bact_S13; TIGR03631
1006551002660	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
1006551002661	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1006551002662	SecY translocase; Region: SecY; pfam00344
1006551002663	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1006551002664	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
1006551002665	23S rRNA binding site [nucleotide binding]; other site
1006551002666	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
1006551002667	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1006551002668	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1006551002669	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1006551002670	23S rRNA interface [nucleotide binding]; other site
1006551002671	5S rRNA interface [nucleotide binding]; other site
1006551002672	L27 interface [polypeptide binding]; other site
1006551002673	L5 interface [polypeptide binding]; other site
1006551002674	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1006551002675	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1006551002676	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1006551002677	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1006551002678	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
1006551002679	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1006551002680	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1006551002681	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1006551002682	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
1006551002683	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1006551002684	RNA binding site [nucleotide binding]; other site
1006551002685	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
1006551002686	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1006551002687	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1006551002688	23S rRNA interface [nucleotide binding]; other site
1006551002689	putative translocon interaction site; other site
1006551002690	signal recognition particle (SRP54) interaction site; other site
1006551002691	L23 interface [polypeptide binding]; other site
1006551002692	trigger factor interaction site; other site
1006551002693	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1006551002694	23S rRNA interface [nucleotide binding]; other site
1006551002695	5S rRNA interface [nucleotide binding]; other site
1006551002696	putative antibiotic binding site [chemical binding]; other site
1006551002697	L25 interface [polypeptide binding]; other site
1006551002698	L27 interface [polypeptide binding]; other site
1006551002699	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1006551002700	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1006551002701	G-X-X-G motif; other site
1006551002702	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1006551002703	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1006551002704	protein-rRNA interface [nucleotide binding]; other site
1006551002705	putative translocon binding site; other site
1006551002706	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
1006551002707	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1006551002708	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1006551002709	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1006551002710	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1006551002711	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1006551002712	50S ribosomal protein L3, bacterial; Region: L3_bact; TIGR03625
1006551002713	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1006551002714	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
1006551002715	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
1006551002716	Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193
1006551002717	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
1006551002718	heme binding site [chemical binding]; other site
1006551002719	ferroxidase pore; other site
1006551002720	ferroxidase diiron center [ion binding]; other site
1006551002721	bacterioferritin-associated ferredoxin; Provisional; Region: PRK10509
1006551002722	elongation factor Tu; Reviewed; Region: PRK00049
1006551002723	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1006551002724	G1 box; other site
1006551002725	GEF interaction site [polypeptide binding]; other site
1006551002726	GTP/Mg2+ binding site [chemical binding]; other site
1006551002727	Switch I region; other site
1006551002728	G2 box; other site
1006551002729	G3 box; other site
1006551002730	Switch II region; other site
1006551002731	G4 box; other site
1006551002732	G5 box; other site
1006551002733	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1006551002734	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1006551002735	Antibiotic Binding Site [chemical binding]; other site
1006551002736	elongation factor G; Reviewed; Region: PRK00007
1006551002737	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1006551002738	G1 box; other site
1006551002739	putative GEF interaction site [polypeptide binding]; other site
1006551002740	GTP/Mg2+ binding site [chemical binding]; other site
1006551002741	Switch I region; other site
1006551002742	G2 box; other site
1006551002743	G3 box; other site
1006551002744	Switch II region; other site
1006551002745	G4 box; other site
1006551002746	G5 box; other site
1006551002747	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1006551002748	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1006551002749	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1006551002750	30S ribosomal protein S7; Validated; Region: PRK05302
1006551002751	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
1006551002752	S17 interaction site [polypeptide binding]; other site
1006551002753	S8 interaction site; other site
1006551002754	16S rRNA interaction site [nucleotide binding]; other site
1006551002755	streptomycin interaction site [chemical binding]; other site
1006551002756	23S rRNA interaction site [nucleotide binding]; other site
1006551002757	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
1006551002758	DsrH like protein; Region: DsrH; cl17347
1006551002759	sulfur relay protein TusC; Validated; Region: PRK00211
1006551002760	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
1006551002761	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
1006551002762	YheO-like PAS domain; Region: PAS_6; pfam08348
1006551002763	HTH domain; Region: HTH_22; pfam13309
1006551002764	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902
1006551002765	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1006551002766	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1006551002767	phi X174 lysis protein; Provisional; Region: PRK02793
1006551002768	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10737
1006551002769	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1006551002770	Predicted nucleic-acid-binding protein containing a Zn-ribbon domain [General function prediction only]; Region: COG3529
1006551002771	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
1006551002772	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
1006551002773	TrkA-N domain; Region: TrkA_N; pfam02254
1006551002774	glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930
1006551002775	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
1006551002776	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551002777	Walker A/P-loop; other site
1006551002778	ATP binding site [chemical binding]; other site
1006551002779	Q-loop/lid; other site
1006551002780	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1006551002781	ABC transporter signature motif; other site
1006551002782	Walker B; other site
1006551002783	D-loop; other site
1006551002784	ABC transporter; Region: ABC_tran_2; pfam12848
1006551002785	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1006551002786	putative nicotinate phosphoribosyltransferase; Provisional; Region: PRK09198
1006551002787	pre-B-cell colony-enhancing factor (PBEF)-like. The mammalian members of this group of nicotinate phosphoribosyltransferases (NAPRTases) were originally identified as genes whose expression is upregulated upon activation in lymphoid cells. In general; Region: PBEF_like; cd01569
1006551002788	active site
1006551002789	Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism / Amino acid transport and metabolism]; Region: PrsA; COG0462
1006551002790	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1006551002791	active site
1006551002792	ADP-ribose pyrophosphatase [Nucleotide transport and metabolism]; Region: COG1051
1006551002793	nudix motif; other site
1006551002794	Uncharacterized conserved protein [General function prediction only]; Region: COG4111
1006551002795	putative hydrolase; Provisional; Region: PRK10985
1006551002796	hypothetical protein; Provisional; Region: PRK04966
1006551002797	Phosphoribulokinase-like (PRK-like) is a family of proteins similar to phosphoribulokinase (PRK), the enzyme involved in the Benson-Calvin cycle in chloroplasts or photosynthetic prokaryotes. PRK catalyzes the phosphorylation of D-ribulose 5-phosphate to...; Region: PRK_like; cd02029
1006551002798	active site
1006551002799	hypothetical protein; Provisional; Region: PRK10738
1006551002800	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
1006551002801	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1006551002802	ligand binding site [chemical binding]; other site
1006551002803	flexible hinge region; other site
1006551002804	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1006551002805	putative switch regulator; other site
1006551002806	non-specific DNA interactions [nucleotide binding]; other site
1006551002807	DNA binding site [nucleotide binding]
1006551002808	sequence specific DNA binding site [nucleotide binding]; other site
1006551002809	putative cAMP binding site [chemical binding]; other site
1006551002810	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
1006551002811	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
1006551002812	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1006551002813	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
1006551002814	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1006551002815	inhibitor-cofactor binding pocket; inhibition site
1006551002816	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551002817	catalytic residue [active]
1006551002818	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
1006551002819	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1006551002820	glutamine binding [chemical binding]; other site
1006551002821	catalytic triad [active]
1006551002822	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
1006551002823	cell filamentation protein Fic; Provisional; Region: PRK10347
1006551002824	hypothetical protein; Provisional; Region: PRK10204
1006551002825	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
1006551002826	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
1006551002827	substrate binding site [chemical binding]; other site
1006551002828	putative transporter; Provisional; Region: PRK03699
1006551002829	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551002830	putative substrate translocation pore; other site
1006551002831	cytosine deaminase; Provisional; Region: PRK09230
1006551002832	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
1006551002833	active site
1006551002834	nitrite reductase subunit NirD; Provisional; Region: PRK14989
1006551002835	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1006551002836	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1006551002837	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1006551002838	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1006551002839	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
1006551002840	nitrite transporter NirC; Provisional; Region: PRK11562
1006551002841	siroheme synthase; Provisional; Region: cysG; PRK10637
1006551002842	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
1006551002843	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
1006551002844	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
1006551002845	active site
1006551002846	SAM binding site [chemical binding]; other site
1006551002847	homodimer interface [polypeptide binding]; other site
1006551002848	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1006551002849	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1006551002850	active site
1006551002851	HIGH motif; other site
1006551002852	dimer interface [polypeptide binding]; other site
1006551002853	KMSKS motif; other site
1006551002854	phosphoglycolate phosphatase; Provisional; Region: PRK13222
1006551002855	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
1006551002856	motif I; other site
1006551002857	active site
1006551002858	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1006551002859	motif II; other site
1006551002860	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1006551002861	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
1006551002862	substrate binding site [chemical binding]; other site
1006551002863	hexamer interface [polypeptide binding]; other site
1006551002864	metal binding site [ion binding]; metal-binding site
1006551002865	DNA adenine methylase; Provisional; Region: PRK10904
1006551002866	cell division protein DamX; Validated; Region: PRK10905
1006551002867	cell division protein DamX; Validated; Region: PRK10905
1006551002868	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
1006551002869	active site
1006551002870	dimer interface [polypeptide binding]; other site
1006551002871	metal binding site [ion binding]; metal-binding site
1006551002872	shikimate kinase; Reviewed; Region: aroK; PRK00131
1006551002873	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1006551002874	ADP binding site [chemical binding]; other site
1006551002875	magnesium binding site [ion binding]; other site
1006551002876	putative shikimate binding site; other site
1006551002877	outer membrane porin HofQ; Provisional; Region: hofQ; PRK10560
1006551002878	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1006551002879	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1006551002880	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
1006551002881	Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilM; COG4972
1006551002882	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
1006551002883	Transglycosylase; Region: Transgly; pfam00912
1006551002884	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1006551002885	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
1006551002886	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1006551002887	ADP-ribose binding site [chemical binding]; other site
1006551002888	dimer interface [polypeptide binding]; other site
1006551002889	active site
1006551002890	nudix motif; other site
1006551002891	metal binding site [ion binding]; metal-binding site
1006551002892	Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095
1006551002893	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
1006551002894	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1006551002895	motif II; other site
1006551002896	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1006551002897	RNA binding surface [nucleotide binding]; other site
1006551002898	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
1006551002899	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
1006551002900	dimerization interface [polypeptide binding]; other site
1006551002901	domain crossover interface; other site
1006551002902	redox-dependent activation switch; other site
1006551002903	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
1006551002904	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
1006551002905	active site
1006551002906	substrate-binding site [chemical binding]; other site
1006551002907	metal-binding site [ion binding]
1006551002908	ATP binding site [chemical binding]; other site
1006551002909	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
1006551002910	4-alpha-glucanotransferase; Region: Glyco_hydro_77; cl00711
1006551002911	maltodextrin phosphorylase; Provisional; Region: PRK14985
1006551002912	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
1006551002913	homodimer interface [polypeptide binding]; other site
1006551002914	active site pocket [active]
1006551002915	transcriptional regulator MalT; Provisional; Region: PRK04841
1006551002916	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1006551002917	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1006551002918	DNA binding residues [nucleotide binding]
1006551002919	dimerization interface [polypeptide binding]; other site
1006551002920	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
1006551002921	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1006551002922	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1006551002923	intramembrane serine protease GlpG; Provisional; Region: PRK10907
1006551002924	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
1006551002925	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
1006551002926	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
1006551002927	active site residue [active]
1006551002928	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
1006551002929	glycogen phosphorylase; Provisional; Region: PRK14986
1006551002930	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
1006551002931	homodimer interface [polypeptide binding]; other site
1006551002932	active site pocket [active]
1006551002933	glycogen synthase; Provisional; Region: glgA; PRK00654
1006551002934	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
1006551002935	ADP-binding pocket [chemical binding]; other site
1006551002936	homodimer interface [polypeptide binding]; other site
1006551002937	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
1006551002938	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
1006551002939	ligand binding site; other site
1006551002940	oligomer interface; other site
1006551002941	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
1006551002942	dimer interface [polypeptide binding]; other site
1006551002943	N-terminal domain interface [polypeptide binding]; other site
1006551002944	sulfate 1 binding site; other site
1006551002945	glycogen debranching enzyme; Provisional; Region: PRK03705
1006551002946	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
1006551002947	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
1006551002948	active site
1006551002949	catalytic site [active]
1006551002950	glycogen branching enzyme; Provisional; Region: PRK05402
1006551002951	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
1006551002952	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
1006551002953	active site
1006551002954	catalytic site [active]
1006551002955	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
1006551002956	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
1006551002957	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1006551002958	low affinity gluconate transporter; Provisional; Region: PRK10472
1006551002959	gluconate transporter; Region: gntP; TIGR00791
1006551002960	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
1006551002961	ATP-binding site [chemical binding]; other site
1006551002962	Gluconate-6-phosphate binding site [chemical binding]; other site
1006551002963	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
1006551002964	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1006551002965	DNA binding site [nucleotide binding]
1006551002966	domain linker motif; other site
1006551002967	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1006551002968	putative ligand binding site [chemical binding]; other site
1006551002969	putative dimerization interface [polypeptide binding]; other site
1006551002970	Pirin-related protein [General function prediction only]; Region: COG1741
1006551002971	Pirin; Region: Pirin; pfam02678
1006551002972	putative oxidoreductase; Provisional; Region: PRK10206
1006551002973	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1006551002974	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1006551002975	Integral membrane protein CcmA involved in cell shape determination [Cell envelope biogenesis, outer membrane]; Region: CcmA; COG1664
1006551002976	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
1006551002977	putative acetyltransferase YhhY; Provisional; Region: PRK10140
1006551002978	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1006551002979	Coenzyme A binding pocket [chemical binding]; other site
1006551002980	gamma-glutamyltranspeptidase; Reviewed; Region: ggt; PRK09615
1006551002981	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
1006551002982	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
1006551002983	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
1006551002984	putative active site [active]
1006551002985	catalytic site [active]
1006551002986	putative metal binding site [ion binding]; other site
1006551002987	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
1006551002988	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1006551002989	Walker A/P-loop; other site
1006551002990	ATP binding site [chemical binding]; other site
1006551002991	Q-loop/lid; other site
1006551002992	ABC transporter signature motif; other site
1006551002993	Walker B; other site
1006551002994	D-loop; other site
1006551002995	H-loop/switch region; other site
1006551002996	TOBE domain; Region: TOBE_2; pfam08402
1006551002997	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1006551002998	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551002999	dimer interface [polypeptide binding]; other site
1006551003000	conserved gate region; other site
1006551003001	ABC-ATPase subunit interface; other site
1006551003002	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1006551003003	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551003004	dimer interface [polypeptide binding]; other site
1006551003005	conserved gate region; other site
1006551003006	putative PBP binding loops; other site
1006551003007	ABC-ATPase subunit interface; other site
1006551003008	glycerol-3-phosphate transporter periplasmic binding protein; Provisional; Region: PRK10974
1006551003009	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1006551003010	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1006551003011	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
1006551003012	Bacterial transcriptional regulator; Region: IclR; pfam01614
1006551003013	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
1006551003014	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1006551003015	inhibitor site; inhibition site
1006551003016	active site
1006551003017	dimer interface [polypeptide binding]; other site
1006551003018	catalytic residue [active]
1006551003019	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
1006551003020	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551003021	putative substrate translocation pore; other site
1006551003022	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
1006551003023	galactarate dehydratase; Region: galactar-dH20; TIGR03248
1006551003024	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
1006551003025	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livF; PRK11614
1006551003026	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
1006551003027	Walker A/P-loop; other site
1006551003028	ATP binding site [chemical binding]; other site
1006551003029	Q-loop/lid; other site
1006551003030	ABC transporter signature motif; other site
1006551003031	Walker B; other site
1006551003032	D-loop; other site
1006551003033	H-loop/switch region; other site
1006551003034	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
1006551003035	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
1006551003036	Walker A/P-loop; other site
1006551003037	ATP binding site [chemical binding]; other site
1006551003038	Q-loop/lid; other site
1006551003039	ABC transporter signature motif; other site
1006551003040	Walker B; other site
1006551003041	D-loop; other site
1006551003042	H-loop/switch region; other site
1006551003043	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
1006551003044	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
1006551003045	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
1006551003046	TM-ABC transporter signature motif; other site
1006551003047	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1006551003048	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
1006551003049	TM-ABC transporter signature motif; other site
1006551003050	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1006551003051	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
1006551003052	dimerization interface [polypeptide binding]; other site
1006551003053	ligand binding site [chemical binding]; other site
1006551003054	Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568
1006551003055	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1006551003056	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
1006551003057	dimerization interface [polypeptide binding]; other site
1006551003058	ligand binding site [chemical binding]; other site
1006551003059	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1006551003060	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
1006551003061	4-aminobutyrate aminotransferase; Provisional; Region: PRK06777
1006551003062	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1006551003063	inhibitor-cofactor binding pocket; inhibition site
1006551003064	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551003065	catalytic residue [active]
1006551003066	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1006551003067	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551003068	DNA-binding site [nucleotide binding]; DNA binding site
1006551003069	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1006551003070	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551003071	homodimer interface [polypeptide binding]; other site
1006551003072	catalytic residue [active]
1006551003073	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
1006551003074	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1006551003075	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1006551003076	DNA binding residues [nucleotide binding]
1006551003077	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
1006551003078	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
1006551003079	cell division protein FtsE; Provisional; Region: PRK10908
1006551003080	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551003081	Walker A/P-loop; other site
1006551003082	ATP binding site [chemical binding]; other site
1006551003083	Q-loop/lid; other site
1006551003084	ABC transporter signature motif; other site
1006551003085	Walker B; other site
1006551003086	D-loop; other site
1006551003087	H-loop/switch region; other site
1006551003088	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
1006551003089	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
1006551003090	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1006551003091	P loop; other site
1006551003092	GTP binding site [chemical binding]; other site
1006551003093	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
1006551003094	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551003095	S-adenosylmethionine binding site [chemical binding]; other site
1006551003096	hypothetical protein; Provisional; Region: PRK10910
1006551003097	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
1006551003098	Predicted membrane protein [Function unknown]; Region: COG3714
1006551003099	zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033
1006551003100	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1006551003101	metal-binding site [ion binding]
1006551003102	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1006551003103	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
1006551003104	CPxP  motif; other site
1006551003105	hypothetical protein; Provisional; Region: PRK11212
1006551003106	hypothetical protein; Provisional; Region: PRK11615
1006551003107	major facilitator superfamily transporter; Provisional; Region: PRK05122
1006551003108	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551003109	putative substrate translocation pore; other site
1006551003110	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
1006551003111	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1006551003112	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1006551003113	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551003114	S-adenosylmethionine binding site [chemical binding]; other site
1006551003115	S-adenosyl-L-methionine-dependent methyltransferase; Region: Methyltransf_30; cl17711
1006551003116	Beta-ketoacyl synthase, N-terminal domain; Region: Ketoacyl-synt_2; pfam13723
1006551003117	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1006551003118	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1006551003119	putative acyl-acceptor binding pocket; other site
1006551003120	Phosphopantetheine attachment site; Region: PP-binding; cl09936
1006551003121	acyl carrier protein; Provisional; Region: PRK05350
1006551003122	Predicted membrane protein [Function unknown]; Region: COG4648
1006551003123	Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Region: Acs; COG0365
1006551003124	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1006551003125	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1006551003126	acyl-activating enzyme (AAE) consensus motif; other site
1006551003127	acyl-activating enzyme (AAE) consensus motif; other site
1006551003128	AMP binding site [chemical binding]; other site
1006551003129	active site
1006551003130	CoA binding site [chemical binding]; other site
1006551003131	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
1006551003132	active site 2 [active]
1006551003133	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1006551003134	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
1006551003135	Ligand binding site; other site
1006551003136	Putative Catalytic site; other site
1006551003137	DXD motif; other site
1006551003138	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1006551003139	putative acyl-acceptor binding pocket; other site
1006551003140	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1006551003141	active site
1006551003142	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl17548
1006551003143	Predicted exporter [General function prediction only]; Region: COG4258
1006551003144	Protein of unknown function (DUF3261); Region: DUF3261; pfam11659
1006551003145	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK09185
1006551003146	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1006551003147	dimer interface [polypeptide binding]; other site
1006551003148	active site
1006551003149	Domain of unknown function, appears to be related to a diverse group of beta-hydroxydecanoyl ACP dehydratases (FabA) and beta-hydroxyacyl ACP dehydratases (FabZ). This group appears to lack the conserved active site histidine of FabA and FabZ; Region: FabA_like; cd01289
1006551003150	putative active site 1 [active]
1006551003151	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1006551003152	3-oxoacyl-(acyl-carrier-protein) reductase, putative; Region: fabG_rel; TIGR01831
1006551003153	NAD(P) binding site [chemical binding]; other site
1006551003154	active site
1006551003155	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK09116
1006551003156	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1006551003157	dimer interface [polypeptide binding]; other site
1006551003158	active site
1006551003159	holo-(acyl carrier protein) synthase 2; Provisional; Region: PRK10351
1006551003160	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
1006551003161	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
1006551003162	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
1006551003163	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
1006551003164	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
1006551003165	4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394
1006551003166	Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692
1006551003167	bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Validated; Region: PRK08125
1006551003168	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
1006551003169	active site
1006551003170	substrate binding site [chemical binding]; other site
1006551003171	cosubstrate binding site; other site
1006551003172	catalytic site [active]
1006551003173	C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702
1006551003174	active site
1006551003175	hexamer interface [polypeptide binding]; other site
1006551003176	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
1006551003177	NAD binding site [chemical binding]; other site
1006551003178	substrate binding site [chemical binding]; other site
1006551003179	active site
1006551003180	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
1006551003181	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1006551003182	Putative Catalytic site; other site
1006551003183	DXD motif; other site
1006551003184	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1006551003185	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1006551003186	inhibitor-cofactor binding pocket; inhibition site
1006551003187	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551003188	catalytic residue [active]
1006551003189	Phenolic acid decarboxylase (PAD); Region: PA_decarbox; pfam05870
1006551003190	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551003191	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551003192	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1006551003193	dimerization interface [polypeptide binding]; other site
1006551003194	The substrate-binding component of an ABC-type nickel import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA; cd08489
1006551003195	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1006551003196	substrate binding site [chemical binding]; other site
1006551003197	nickel transporter permease NikB; Provisional; Region: PRK10352
1006551003198	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551003199	dimer interface [polypeptide binding]; other site
1006551003200	conserved gate region; other site
1006551003201	putative PBP binding loops; other site
1006551003202	ABC-ATPase subunit interface; other site
1006551003203	nickel transporter permease NikC; Provisional; Region: nikC; PRK10417
1006551003204	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551003205	dimer interface [polypeptide binding]; other site
1006551003206	conserved gate region; other site
1006551003207	putative PBP binding loops; other site
1006551003208	ABC-ATPase subunit interface; other site
1006551003209	nickel transporter ATP-binding protein NikD; Provisional; Region: nikD; PRK10418
1006551003210	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1006551003211	Walker A/P-loop; other site
1006551003212	ATP binding site [chemical binding]; other site
1006551003213	Q-loop/lid; other site
1006551003214	ABC transporter signature motif; other site
1006551003215	Walker B; other site
1006551003216	D-loop; other site
1006551003217	H-loop/switch region; other site
1006551003218	nickel transporter ATP-binding protein NikE; Provisional; Region: nikE; PRK10419
1006551003219	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1006551003220	Walker A/P-loop; other site
1006551003221	ATP binding site [chemical binding]; other site
1006551003222	Q-loop/lid; other site
1006551003223	ABC transporter signature motif; other site
1006551003224	Walker B; other site
1006551003225	D-loop; other site
1006551003226	H-loop/switch region; other site
1006551003227	nickel responsive regulator; Provisional; Region: PRK02967
1006551003228	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
1006551003229	Protein of unknown function (DUF1440); Region: DUF1440; cl01380
1006551003230	FOG: CBS domain [General function prediction only]; Region: COG0517
1006551003231	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
1006551003232	Divalent cation transporter; Region: MgtE; pfam01769
1006551003233	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
1006551003234	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_4; cd12173
1006551003235	ligand binding site [chemical binding]; other site
1006551003236	NAD binding site [chemical binding]; other site
1006551003237	dimerization interface [polypeptide binding]; other site
1006551003238	catalytic site [active]
1006551003239	hypothetical protein; Validated; Region: PRK06201
1006551003240	Demethylmenaquinone methyltransferase [Coenzyme metabolism]; Region: MenG; COG0684
1006551003241	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
1006551003242	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1006551003243	putative metallo-dependent hydrolase; Provisional; Region: PRK12394
1006551003244	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1006551003245	active site
1006551003246	Propionate catabolism activator; Region: PrpR_N; pfam06506
1006551003247	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829
1006551003248	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1006551003249	Walker A motif; other site
1006551003250	ATP binding site [chemical binding]; other site
1006551003251	Walker B motif; other site
1006551003252	arginine finger; other site
1006551003253	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1006551003254	Predicted flavoproteins [General function prediction only]; Region: COG2081
1006551003255	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1006551003256	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1006551003257	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1006551003258	universal stress protein UspB; Provisional; Region: PRK04960
1006551003259	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1006551003260	Ligand Binding Site [chemical binding]; other site
1006551003261	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
1006551003262	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551003263	POT family; Region: PTR2; pfam00854
1006551003264	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551003265	S-adenosylmethionine binding site [chemical binding]; other site
1006551003266	oligopeptidase A; Provisional; Region: PRK10911
1006551003267	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
1006551003268	active site
1006551003269	Zn binding site [ion binding]; other site
1006551003270	high-affinity gluconate transporter; Provisional; Region: PRK14984
1006551003271	gluconate transporter; Region: gntP; TIGR00791
1006551003272	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
1006551003273	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
1006551003274	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
1006551003275	DNA utilization protein GntX; Provisional; Region: PRK11595
1006551003276	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1006551003277	active site
1006551003278	carboxylesterase BioH; Provisional; Region: PRK10349
1006551003279	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
1006551003280	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1006551003281	ferrous iron transport protein FeoC; Provisional; Region: PRK15431
1006551003282	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
1006551003283	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
1006551003284	G1 box; other site
1006551003285	GTP/Mg2+ binding site [chemical binding]; other site
1006551003286	Switch I region; other site
1006551003287	G2 box; other site
1006551003288	G3 box; other site
1006551003289	Switch II region; other site
1006551003290	G4 box; other site
1006551003291	G5 box; other site
1006551003292	Nucleoside recognition; Region: Gate; pfam07670
1006551003293	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
1006551003294	Nucleoside recognition; Region: Gate; pfam07670
1006551003295	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
1006551003296	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
1006551003297	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
1006551003298	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
1006551003299	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
1006551003300	RNA binding site [nucleotide binding]; other site
1006551003301	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
1006551003302	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1006551003303	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1006551003304	osmolarity response regulator; Provisional; Region: ompR; PRK09468
1006551003305	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551003306	active site
1006551003307	phosphorylation site [posttranslational modification]
1006551003308	intermolecular recognition site; other site
1006551003309	dimerization interface [polypeptide binding]; other site
1006551003310	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1006551003311	DNA binding site [nucleotide binding]
1006551003312	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
1006551003313	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1006551003314	dimerization interface [polypeptide binding]; other site
1006551003315	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1006551003316	dimer interface [polypeptide binding]; other site
1006551003317	phosphorylation site [posttranslational modification]
1006551003318	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551003319	ATP binding site [chemical binding]; other site
1006551003320	Mg2+ binding site [ion binding]; other site
1006551003321	G-X-G motif; other site
1006551003322	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
1006551003323	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1006551003324	active site
1006551003325	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
1006551003326	glutathione reductase; Validated; Region: PRK06116
1006551003327	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1006551003328	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1006551003329	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1006551003330	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1006551003331	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
1006551003332	putative C-terminal domain interface [polypeptide binding]; other site
1006551003333	putative GSH binding site (G-site) [chemical binding]; other site
1006551003334	putative dimer interface [polypeptide binding]; other site
1006551003335	C-terminal, alpha helical domain of an unknown subfamily 2 of Glutathione S-transferases; Region: GST_C_2; cd03180
1006551003336	putative N-terminal domain interface [polypeptide binding]; other site
1006551003337	putative dimer interface [polypeptide binding]; other site
1006551003338	putative substrate binding pocket (H-site) [chemical binding]; other site
1006551003339	Iron-containing alcohol dehydrogenases-like; Region: Fe-ADH2; cd08183
1006551003340	Iron-containing alcohol dehydrogenase; Region: Fe-ADH; pfam00465
1006551003341	putative active site [active]
1006551003342	metal binding site [ion binding]; metal-binding site
1006551003343	trehalase; Provisional; Region: treF; PRK13270
1006551003344	Trehalase; Region: Trehalase; pfam01204
1006551003345	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1006551003346	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1006551003347	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
1006551003348	catalytic residue [active]
1006551003349	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1006551003350	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1006551003351	DNA binding residues [nucleotide binding]
1006551003352	dimerization interface [polypeptide binding]; other site
1006551003353	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1006551003354	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1006551003355	NAD(P) binding site [chemical binding]; other site
1006551003356	active site
1006551003357	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551003358	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551003359	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
1006551003360	putative effector binding pocket; other site
1006551003361	putative dimerization interface [polypeptide binding]; other site
1006551003362	inner membrane protein YhjD; Region: TIGR00766
1006551003363	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551003364	metabolite-proton symporter; Region: 2A0106; TIGR00883
1006551003365	putative substrate translocation pore; other site
1006551003366	potential frameshift: common BLAST hit: gi|288933110|ref|YP_003437169.1| AsmA family protein
1006551003367	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1006551003368	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1006551003369	substrate binding site [chemical binding]; other site
1006551003370	ATP binding site [chemical binding]; other site
1006551003371	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1006551003372	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1006551003373	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
1006551003374	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1006551003375	putative diguanylate cyclase; Provisional; Region: PRK13561
1006551003376	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1006551003377	metal binding site [ion binding]; metal-binding site
1006551003378	active site
1006551003379	I-site; other site
1006551003380	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1006551003381	cellulose synthase subunit BcsC; Provisional; Region: PRK11447
1006551003382	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1006551003383	TPR motif; other site
1006551003384	binding surface
1006551003385	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1006551003386	TPR motif; other site
1006551003387	binding surface
1006551003388	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
1006551003389	endo-1,4-D-glucanase; Provisional; Region: PRK11097
1006551003390	cellulose synthase regulator protein; Provisional; Region: PRK11114
1006551003391	Probable transposase; Region: OrfB_IS605; pfam01385
1006551003392	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
1006551003393	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
1006551003394	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
1006551003395	cellulose synthase catalytic subunit; Provisional; Region: bcsA; PRK11498
1006551003396	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1006551003397	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
1006551003398	DXD motif; other site
1006551003399	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1006551003400	PilZ domain; Region: PilZ; pfam07238
1006551003401	cell division protein; Provisional; Region: PRK10037
1006551003402	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1006551003403	Protein of unknown function (DUF2629); Region: DUF2629; pfam10945
1006551003404	cellulose biosynthesis protein BcsE; Provisional; Region: PRK15045
1006551003405	Protein of unknown function (DUF2819); Region: DUF2819; pfam10995
1006551003406	Protein of unknown function (DUF2636); Region: DUF2636; pfam11120
1006551003407	Protein of unknown function (DUF3260); Region: DUF3260; pfam11658
1006551003408	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
1006551003409	Glycosyl hydrolases family 8; Region: Glyco_hydro_8; cl01351
1006551003410	Cellulose synthase subunit D; Region: Cellsynth_D; pfam03500
1006551003411	cellulose synthase subunit BcsC; Provisional; Region: PRK11447
1006551003412	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1006551003413	binding surface
1006551003414	TPR motif; other site
1006551003415	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
1006551003416	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
1006551003417	cellulose synthase regulator protein; Provisional; Region: PRK11114
1006551003418	cellulose synthase catalytic subunit (UDP-forming); Region: CelA; TIGR03030
1006551003419	Cellulose synthase-like protein; Region: PLN02893
1006551003420	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
1006551003421	DXD motif; other site
1006551003422	PilZ domain; Region: PilZ; pfam07238
1006551003423	cellulose synthase operon protein YhjQ; Region: cellulose_yhjQ; TIGR03371
1006551003424	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1006551003425	P-loop; other site
1006551003426	Magnesium ion binding site [ion binding]; other site
1006551003427	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
1006551003428	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1006551003429	Walker A/P-loop; other site
1006551003430	ATP binding site [chemical binding]; other site
1006551003431	Q-loop/lid; other site
1006551003432	ABC transporter signature motif; other site
1006551003433	Walker B; other site
1006551003434	D-loop; other site
1006551003435	H-loop/switch region; other site
1006551003436	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1006551003437	dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022
1006551003438	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1006551003439	Walker A/P-loop; other site
1006551003440	ATP binding site [chemical binding]; other site
1006551003441	Q-loop/lid; other site
1006551003442	ABC transporter signature motif; other site
1006551003443	Walker B; other site
1006551003444	D-loop; other site
1006551003445	H-loop/switch region; other site
1006551003446	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1006551003447	dipeptide transporter; Provisional; Region: PRK10913
1006551003448	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1006551003449	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551003450	putative PBP binding loops; other site
1006551003451	dimer interface [polypeptide binding]; other site
1006551003452	ABC-ATPase subunit interface; other site
1006551003453	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1006551003454	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551003455	dimer interface [polypeptide binding]; other site
1006551003456	conserved gate region; other site
1006551003457	putative PBP binding loops; other site
1006551003458	ABC-ATPase subunit interface; other site
1006551003459	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1006551003460	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1006551003461	peptide binding site [polypeptide binding]; other site
1006551003462	phosphoethanolamine transferase; Provisional; Region: PRK11560
1006551003463	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1006551003464	Sulfatase; Region: Sulfatase; pfam00884
1006551003465	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
1006551003466	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551003467	putative substrate translocation pore; other site
1006551003468	Autotransporter beta-domain; Region: Autotransporter; cl17461
1006551003469	Methyladenine glycosylase; Region: Adenine_glyco; cl01059
1006551003470	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1006551003471	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1006551003472	Coenzyme A binding pocket [chemical binding]; other site
1006551003473	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
1006551003474	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
1006551003475	molybdopterin cofactor binding site [chemical binding]; other site
1006551003476	substrate binding site [chemical binding]; other site
1006551003477	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
1006551003478	molybdopterin cofactor binding site; other site
1006551003479	putative outer membrane lipoprotein; Provisional; Region: PRK10510
1006551003480	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1006551003481	ligand binding site [chemical binding]; other site
1006551003482	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1006551003483	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1006551003484	DNA binding site [nucleotide binding]
1006551003485	domain linker motif; other site
1006551003486	Ligand-binding domain of DNA transcription repressor RegR and other putative regulators such as KdgR and EndR; Region: PBP1_RegR_EndR_KdgR_like; cd06283
1006551003487	putative dimerization interface [polypeptide binding]; other site
1006551003488	putative ligand binding site [chemical binding]; other site
1006551003489	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
1006551003490	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1006551003491	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1006551003492	substrate binding site [chemical binding]; other site
1006551003493	ATP binding site [chemical binding]; other site
1006551003494	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551003495	D-galactonate transporter; Region: 2A0114; TIGR00893
1006551003496	putative substrate translocation pore; other site
1006551003497	bifunctional glyoxylate/hydroxypyruvate reductase B; Provisional; Region: PRK15409
1006551003498	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
1006551003499	dimerization interface [polypeptide binding]; other site
1006551003500	ligand binding site [chemical binding]; other site
1006551003501	NADP binding site [chemical binding]; other site
1006551003502	catalytic site [active]
1006551003503	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
1006551003504	benzoate transport; Region: 2A0115; TIGR00895
1006551003505	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551003506	putative substrate translocation pore; other site
1006551003507	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551003508	Predicted transcriptional regulator [Transcription]; Region: COG2944
1006551003509	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1006551003510	salt bridge; other site
1006551003511	non-specific DNA binding site [nucleotide binding]; other site
1006551003512	sequence-specific DNA binding site [nucleotide binding]; other site
1006551003513	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1006551003514	DNA-binding site [nucleotide binding]; DNA binding site
1006551003515	RNA-binding motif; other site
1006551003516	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1006551003517	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551003518	Walker A/P-loop; other site
1006551003519	ATP binding site [chemical binding]; other site
1006551003520	Q-loop/lid; other site
1006551003521	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1006551003522	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1006551003523	Hok/gef family; Region: HOK_GEF; cl11494
1006551003524	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
1006551003525	DALR anticodon binding domain; Region: DALR_1; pfam05746
1006551003526	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
1006551003527	dimer interface [polypeptide binding]; other site
1006551003528	motif 1; other site
1006551003529	active site
1006551003530	motif 2; other site
1006551003531	motif 3; other site
1006551003532	YsaB-like lipoprotein; Region: YsaB; pfam13983
1006551003533	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
1006551003534	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1006551003535	hypothetical protein; Provisional; Region: PRK11403
1006551003536	yiaA/B two helix domain; Region: YiaAB; pfam05360
1006551003537	xylulokinase; Provisional; Region: PRK15027
1006551003538	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
1006551003539	N- and C-terminal domain interface [polypeptide binding]; other site
1006551003540	active site
1006551003541	MgATP binding site [chemical binding]; other site
1006551003542	catalytic site [active]
1006551003543	metal binding site [ion binding]; metal-binding site
1006551003544	xylulose binding site [chemical binding]; other site
1006551003545	homodimer interface [polypeptide binding]; other site
1006551003546	xylose isomerase; Provisional; Region: PRK05474
1006551003547	xylose isomerase; Region: xylose_isom_A; TIGR02630
1006551003548	D-xylose transporter subunit XylF; Provisional; Region: xylF; PRK10355
1006551003549	Periplasmic xylose-binding component of the ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_xylose_binding; cd01538
1006551003550	putative ligand binding site [chemical binding]; other site
1006551003551	xylose transporter ATP-binding subunit; Provisional; Region: PRK13549
1006551003552	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1006551003553	Walker A/P-loop; other site
1006551003554	ATP binding site [chemical binding]; other site
1006551003555	Q-loop/lid; other site
1006551003556	ABC transporter signature motif; other site
1006551003557	Walker B; other site
1006551003558	D-loop; other site
1006551003559	H-loop/switch region; other site
1006551003560	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1006551003561	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1006551003562	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1006551003563	TM-ABC transporter signature motif; other site
1006551003564	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
1006551003565	putative dimerization interface [polypeptide binding]; other site
1006551003566	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1006551003567	putative ligand binding site [chemical binding]; other site
1006551003568	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551003569	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1006551003570	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551003571	Uncharacterized FlgJ-related protein [General function prediction only]; Region: Bax; COG2992
1006551003572	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; cl17361
1006551003573	alpha-amylase; Reviewed; Region: malS; PRK09505
1006551003574	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
1006551003575	active site
1006551003576	catalytic site [active]
1006551003577	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
1006551003578	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1006551003579	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551003580	homodimer interface [polypeptide binding]; other site
1006551003581	catalytic residue [active]
1006551003582	formate dehydrogenase-H ferredoxin subunit; Provisional; Region: PRK10330
1006551003583	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1006551003584	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1006551003585	Bacterial transcriptional regulator; Region: IclR; pfam01614
1006551003586	2,3-diketo-L-gulonate reductase; Provisional; Region: PRK13260
1006551003587	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1006551003588	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551003589	D-galactonate transporter; Region: 2A0114; TIGR00893
1006551003590	putative substrate translocation pore; other site
1006551003591	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
1006551003592	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
1006551003593	putative N- and C-terminal domain interface [polypeptide binding]; other site
1006551003594	putative active site [active]
1006551003595	MgATP binding site [chemical binding]; other site
1006551003596	catalytic site [active]
1006551003597	metal binding site [ion binding]; metal-binding site
1006551003598	putative xylulose binding site [chemical binding]; other site
1006551003599	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
1006551003600	active site
1006551003601	dimer interface [polypeptide binding]; other site
1006551003602	magnesium binding site [ion binding]; other site
1006551003603	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
1006551003604	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1006551003605	AP (apurinic/apyrimidinic) site pocket; other site
1006551003606	DNA interaction; other site
1006551003607	Metal-binding active site; metal-binding site
1006551003608	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1006551003609	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1006551003610	intersubunit interface [polypeptide binding]; other site
1006551003611	active site
1006551003612	Zn2+ binding site [ion binding]; other site
1006551003613	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1006551003614	Helix-turn-helix domain; Region: HTH_18; pfam12833
1006551003615	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551003616	potential frameshift: common BLAST hit: gi|317048886|ref|YP_004116534.1| sugar (Glycoside-Pentoside-Hexuronide) transporter
1006551003617	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
1006551003618	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
1006551003619	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
1006551003620	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
1006551003621	G1 box; other site
1006551003622	putative GEF interaction site [polypeptide binding]; other site
1006551003623	GTP/Mg2+ binding site [chemical binding]; other site
1006551003624	Switch I region; other site
1006551003625	G2 box; other site
1006551003626	G3 box; other site
1006551003627	Switch II region; other site
1006551003628	G4 box; other site
1006551003629	G5 box; other site
1006551003630	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
1006551003631	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
1006551003632	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
1006551003633	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
1006551003634	selenocysteine synthase; Provisional; Region: PRK04311
1006551003635	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
1006551003636	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
1006551003637	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1006551003638	catalytic residue [active]
1006551003639	putative glutathione S-transferase; Provisional; Region: PRK10357
1006551003640	GST_N family, unknown subfamily 3; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_3; cd03049
1006551003641	putative C-terminal domain interface [polypeptide binding]; other site
1006551003642	putative GSH binding site (G-site) [chemical binding]; other site
1006551003643	putative dimer interface [polypeptide binding]; other site
1006551003644	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
1006551003645	dimer interface [polypeptide binding]; other site
1006551003646	N-terminal domain interface [polypeptide binding]; other site
1006551003647	putative substrate binding pocket (H-site) [chemical binding]; other site
1006551003648	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
1006551003649	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1006551003650	HlyD family secretion protein; Region: HlyD_3; pfam13437
1006551003651	Protein of unknown function (DUF3302); Region: DUF3302; pfam11742
1006551003652	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
1006551003653	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
1006551003654	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
1006551003655	active site
1006551003656	P-loop; other site
1006551003657	phosphorylation site [posttranslational modification]
1006551003658	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1006551003659	active site
1006551003660	phosphorylation site [posttranslational modification]
1006551003661	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
1006551003662	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1006551003663	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1006551003664	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
1006551003665	mannitol repressor protein; Provisional; Region: mtlR; PRK11001
1006551003666	hypothetical protein; Provisional; Region: PRK11020
1006551003667	L-lactate permease; Provisional; Region: PRK10420
1006551003668	glycolate transporter; Provisional; Region: PRK09695
1006551003669	DNA-binding transcriptional repressor LldR; Provisional; Region: PRK10421
1006551003670	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551003671	DNA-binding site [nucleotide binding]; DNA binding site
1006551003672	FCD domain; Region: FCD; pfam07729
1006551003673	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
1006551003674	Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate...; Region: alpha_hydroxyacid_oxid_FMN; cd02809
1006551003675	active site
1006551003676	substrate binding site [chemical binding]; other site
1006551003677	FMN binding site [chemical binding]; other site
1006551003678	putative catalytic residues [active]
1006551003679	putative rRNA methylase; Provisional; Region: PRK10358
1006551003680	serine acetyltransferase; Provisional; Region: cysE; PRK11132
1006551003681	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
1006551003682	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1006551003683	trimer interface [polypeptide binding]; other site
1006551003684	active site
1006551003685	substrate binding site [chemical binding]; other site
1006551003686	CoA binding site [chemical binding]; other site
1006551003687	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
1006551003688	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1006551003689	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1006551003690	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
1006551003691	SecA binding site; other site
1006551003692	Preprotein binding site; other site
1006551003693	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
1006551003694	GSH binding site [chemical binding]; other site
1006551003695	catalytic residues [active]
1006551003696	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1006551003697	active site residue [active]
1006551003698	phosphoglyceromutase; Provisional; Region: PRK05434
1006551003699	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
1006551003700	AmiB activator; Provisional; Region: PRK11637
1006551003701	Peptidase family M23; Region: Peptidase_M23; pfam01551
1006551003702	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
1006551003703	NodB motif; other site
1006551003704	putative active site [active]
1006551003705	putative catalytic site [active]
1006551003706	Zn binding site [ion binding]; other site
1006551003707	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
1006551003708	putative metal binding site; other site
1006551003709	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
1006551003710	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1006551003711	NAD(P) binding site [chemical binding]; other site
1006551003712	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1006551003713	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
1006551003714	substrate-cofactor binding pocket; other site
1006551003715	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551003716	catalytic residue [active]
1006551003717	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
1006551003718	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
1006551003719	NADP binding site [chemical binding]; other site
1006551003720	homopentamer interface [polypeptide binding]; other site
1006551003721	substrate binding site [chemical binding]; other site
1006551003722	active site
1006551003723	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1006551003724	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1006551003725	putative active site [active]
1006551003726	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1006551003727	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1006551003728	putative active site [active]
1006551003729	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK09822
1006551003730	O-Antigen ligase; Region: Wzy_C; pfam04932
1006551003731	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1006551003732	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1006551003733	Putative catalytic domain of lipopolysaccharide biosynthesis protein WalW and its bacterial homologs; Region: CE4_WalW; cd10935
1006551003734	putative active site [active]
1006551003735	putative catalytic site [active]
1006551003736	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10422
1006551003737	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1006551003738	putative active site [active]
1006551003739	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1006551003740	Glycosyltransferase Family 4; Region: Glyco_transf_4; pfam13439
1006551003741	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1006551003742	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
1006551003743	putative ADP-binding pocket [chemical binding]; other site
1006551003744	putative glycosyl transferase; Provisional; Region: PRK10073
1006551003745	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1006551003746	active site
1006551003747	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
1006551003748	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
1006551003749	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1006551003750	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1006551003751	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
1006551003752	putative metal binding site; other site
1006551003753	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
1006551003754	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
1006551003755	active site
1006551003756	(T/H)XGH motif; other site
1006551003757	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
1006551003758	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
1006551003759	DNA binding site [nucleotide binding]
1006551003760	catalytic residue [active]
1006551003761	H2TH interface [polypeptide binding]; other site
1006551003762	putative catalytic residues [active]
1006551003763	turnover-facilitating residue; other site
1006551003764	intercalation triad [nucleotide binding]; other site
1006551003765	8OG recognition residue [nucleotide binding]; other site
1006551003766	putative reading head residues; other site
1006551003767	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1006551003768	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1006551003769	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
1006551003770	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
1006551003771	hypothetical protein; Reviewed; Region: PRK00024
1006551003772	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1006551003773	MPN+ (JAMM) motif; other site
1006551003774	Zinc-binding site [ion binding]; other site
1006551003775	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
1006551003776	Flavoprotein; Region: Flavoprotein; pfam02441
1006551003777	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
1006551003778	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1006551003779	trimer interface [polypeptide binding]; other site
1006551003780	active site
1006551003781	division inhibitor protein; Provisional; Region: slmA; PRK09480
1006551003782	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1006551003783	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1006551003784	active site
1006551003785	ribonuclease PH; Reviewed; Region: rph; PRK00173
1006551003786	Ribonuclease PH; Region: RNase_PH_bact; cd11362
1006551003787	hexamer interface [polypeptide binding]; other site
1006551003788	active site
1006551003789	hypothetical protein; Provisional; Region: PRK11820
1006551003790	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
1006551003791	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
1006551003792	Putative ClC chloride channel.  Clc proteins are putative halogen ion (Cl-, Br- and I-) transporters found in eubacteria. They belong to the ClC superfamily of halogen ion channels, which share a unique double-barreled architecture and voltage-dependent...; Region: ClC_like; cd01033
1006551003793	putative ion selectivity filter; other site
1006551003794	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1006551003795	putative pore gating glutamate residue; other site
1006551003796	Predicted membrane protein [Function unknown]; Region: COG2860
1006551003797	UPF0126 domain; Region: UPF0126; pfam03458
1006551003798	UPF0126 domain; Region: UPF0126; pfam03458
1006551003799	NAD-dependent DNA ligase LigB; Reviewed; Region: ligB; PRK08097
1006551003800	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cl03295
1006551003801	nucleotide binding pocket [chemical binding]; other site
1006551003802	K-X-D-G motif; other site
1006551003803	catalytic site [active]
1006551003804	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1006551003805	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
1006551003806	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1006551003807	catalytic site [active]
1006551003808	G-X2-G-X-G-K; other site
1006551003809	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
1006551003810	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
1006551003811	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1006551003812	Zn2+ binding site [ion binding]; other site
1006551003813	Mg2+ binding site [ion binding]; other site
1006551003814	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1006551003815	synthetase active site [active]
1006551003816	NTP binding site [chemical binding]; other site
1006551003817	metal binding site [ion binding]; metal-binding site
1006551003818	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1006551003819	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1006551003820	tRNA guanosine-2'-O-methyltransferase; Provisional; Region: PRK11081
1006551003821	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1006551003822	SpoU, rRNA methylase, C-terminal; Region: SpoU_methylas_C; pfam12105
1006551003823	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
1006551003824	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
1006551003825	generic binding surface II; other site
1006551003826	ssDNA binding site; other site
1006551003827	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1006551003828	ATP binding site [chemical binding]; other site
1006551003829	putative Mg++ binding site [ion binding]; other site
1006551003830	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1006551003831	nucleotide binding region [chemical binding]; other site
1006551003832	ATP-binding site [chemical binding]; other site
1006551003833	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
1006551003834	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
1006551003835	putative active site [active]
1006551003836	ferredoxin-NADP reductase; Provisional; Region: PRK10926
1006551003837	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
1006551003838	FAD binding pocket [chemical binding]; other site
1006551003839	FAD binding motif [chemical binding]; other site
1006551003840	phosphate binding motif [ion binding]; other site
1006551003841	beta-alpha-beta structure motif; other site
1006551003842	NAD binding pocket [chemical binding]; other site
1006551003843	Predicted membrane protein [Function unknown]; Region: COG3152
1006551003844	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
1006551003845	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1006551003846	triosephosphate isomerase; Provisional; Region: PRK14567
1006551003847	substrate binding site [chemical binding]; other site
1006551003848	dimer interface [polypeptide binding]; other site
1006551003849	catalytic triad [active]
1006551003850	transmembrane helices; other site
1006551003851	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1006551003852	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
1006551003853	CDP-diacylglycerol pyrophosphatase; Provisional; Region: PRK05471
1006551003854	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1006551003855	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551003856	substrate binding pocket [chemical binding]; other site
1006551003857	membrane-bound complex binding site; other site
1006551003858	septal ring assembly protein ZapB; Provisional; Region: PRK15422
1006551003859	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1006551003860	amphipathic channel; other site
1006551003861	Asn-Pro-Ala signature motifs; other site
1006551003862	glycerol kinase; Provisional; Region: glpK; PRK00047
1006551003863	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
1006551003864	N- and C-terminal domain interface [polypeptide binding]; other site
1006551003865	active site
1006551003866	MgATP binding site [chemical binding]; other site
1006551003867	catalytic site [active]
1006551003868	metal binding site [ion binding]; metal-binding site
1006551003869	glycerol binding site [chemical binding]; other site
1006551003870	homotetramer interface [polypeptide binding]; other site
1006551003871	homodimer interface [polypeptide binding]; other site
1006551003872	FBP binding site [chemical binding]; other site
1006551003873	protein IIAGlc interface [polypeptide binding]; other site
1006551003874	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
1006551003875	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
1006551003876	AsmA family; Region: AsmA; pfam05170
1006551003877	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1006551003878	PTS system, alpha-glucoside-specific IIBC component; Region: PTS-IIBC-alpha; TIGR02005
1006551003879	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1006551003880	active site turn [active]
1006551003881	phosphorylation site [posttranslational modification]
1006551003882	NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195
1006551003883	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
1006551003884	NAD(P) binding site [chemical binding]; other site
1006551003885	LDH/MDH dimer interface [polypeptide binding]; other site
1006551003886	substrate binding site [chemical binding]; other site
1006551003887	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1006551003888	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1006551003889	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1006551003890	putative active site [active]
1006551003891	Protein of unknown function (DUF1498); Region: DUF1498; cl17840
1006551003892	fructokinase; Reviewed; Region: PRK09557
1006551003893	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1006551003894	nucleotide binding site [chemical binding]; other site
1006551003895	Glucokinase; Region: Glucokinase; cl17310
1006551003896	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1006551003897	intersubunit interface [polypeptide binding]; other site
1006551003898	active site
1006551003899	zinc binding site [ion binding]; other site
1006551003900	Na+ binding site [ion binding]; other site
1006551003901	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1006551003902	intersubunit interface [polypeptide binding]; other site
1006551003903	active site
1006551003904	zinc binding site [ion binding]; other site
1006551003905	Na+ binding site [ion binding]; other site
1006551003906	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1006551003907	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1006551003908	active site
1006551003909	P-loop; other site
1006551003910	phosphorylation site [posttranslational modification]
1006551003911	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1006551003912	active site
1006551003913	phosphorylation site [posttranslational modification]
1006551003914	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1006551003915	HTH domain; Region: HTH_11; pfam08279
1006551003916	Mga helix-turn-helix domain; Region: Mga; pfam05043
1006551003917	PRD domain; Region: PRD; pfam00874
1006551003918	PRD domain; Region: PRD; pfam00874
1006551003919	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1006551003920	active site
1006551003921	P-loop; other site
1006551003922	phosphorylation site [posttranslational modification]
1006551003923	putative alpha-glucosidase; Provisional; Region: PRK10658
1006551003924	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1006551003925	YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a...; Region: GH31_xylosidase_YicI; cd06593
1006551003926	active site
1006551003927	homotrimer interface [polypeptide binding]; other site
1006551003928	catalytic site [active]
1006551003929	homohexamer (dimer of homotrimers) interface [polypeptide binding]; other site
1006551003930	putative transporter; Provisional; Region: PRK11462
1006551003931	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1006551003932	potential protein location (hypothetical protein KOX_06160 [Klebsiella oxytoca KCTC 1686]) that overlaps RNA (tRNA-U)
1006551003933	HicB family; Region: HicB; pfam05534
1006551003934	Virulence protein [General function prediction only]; Region: COG3943
1006551003935	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
1006551003936	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
1006551003937	active site
1006551003938	Shikimate kinase; Region: SKI; pfam01202
1006551003939	Protein of unknown function (DUF3237); Region: DUF3237; pfam11578
1006551003940	Arginate lyase and other MDR family members; Region: AL_MDR; cd08252
1006551003941	zinc-binding alcohol dehydrogenase family protein; Region: adh_fam_1; TIGR02817
1006551003942	putative NAD(P) binding site [chemical binding]; other site
1006551003943	dimer interface [polypeptide binding]; other site
1006551003944	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1006551003945	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1006551003946	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
1006551003947	putative NAD(P) binding site [chemical binding]; other site
1006551003948	putative substrate binding site [chemical binding]; other site
1006551003949	catalytic Zn binding site [ion binding]; other site
1006551003950	structural Zn binding site [ion binding]; other site
1006551003951	dimer interface [polypeptide binding]; other site
1006551003952	transcriptional activator FtrA; Provisional; Region: ftrA; PRK09393
1006551003953	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137
1006551003954	conserved cys residue [active]
1006551003955	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551003956	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1006551003957	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
1006551003958	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
1006551003959	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1006551003960	dimer interface [polypeptide binding]; other site
1006551003961	ADP-ribose binding site [chemical binding]; other site
1006551003962	active site
1006551003963	nudix motif; other site
1006551003964	metal binding site [ion binding]; metal-binding site
1006551003965	EamA-like transporter family; Region: EamA; pfam00892
1006551003966	cytoplasmic membrane lipoprotein-28; Provisional; Region: PRK09861
1006551003967	lipoprotein, YaeC family; Region: TIGR00363
1006551003968	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3558
1006551003969	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
1006551003970	Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381
1006551003971	transcriptional regulator; Provisional; Region: PRK10632
1006551003972	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551003973	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_2; cd08471
1006551003974	putative effector binding pocket; other site
1006551003975	putative dimerization interface [polypeptide binding]; other site
1006551003976	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1006551003977	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551003978	putative substrate translocation pore; other site
1006551003979	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551003980	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1006551003981	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1006551003982	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1006551003983	Coenzyme A binding pocket [chemical binding]; other site
1006551003984	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
1006551003985	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1006551003986	HlyD family secretion protein; Region: HlyD_3; pfam13437
1006551003987	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
1006551003988	Protein export membrane protein; Region: SecD_SecF; cl14618
1006551003989	copper/silver efflux system outer membrane protein CusC; Provisional; Region: PRK09837
1006551003990	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
1006551003991	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551003992	putative substrate translocation pore; other site
1006551003993	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
1006551003994	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
1006551003995	putative active site [active]
1006551003996	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
1006551003997	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1006551003998	active site turn [active]
1006551003999	phosphorylation site [posttranslational modification]
1006551004000	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1006551004001	Post-segregation antitoxin CcdA; Region: CcdA; pfam07362
1006551004002	CcdB protein; Region: CcdB; pfam01845
1006551004003	EamA-like transporter family; Region: EamA; pfam00892
1006551004004	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1006551004005	hypothetical protein; Provisional; Region: PRK09956
1006551004006	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1006551004007	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1006551004008	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1006551004009	DNA binding site [nucleotide binding]
1006551004010	domain linker motif; other site
1006551004011	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1006551004012	ligand binding site [chemical binding]; other site
1006551004013	dimerization interface [polypeptide binding]; other site
1006551004014	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1006551004015	active site
1006551004016	P-loop; other site
1006551004017	phosphorylation site [posttranslational modification]
1006551004018	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1006551004019	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1006551004020	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1006551004021	methionine cluster; other site
1006551004022	active site
1006551004023	phosphorylation site [posttranslational modification]
1006551004024	metal binding site [ion binding]; metal-binding site
1006551004025	potential frameshift: common BLAST hit: gi|288932927|ref|YP_003436986.1| porin LamB type
1006551004026	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1006551004027	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551004028	dimer interface [polypeptide binding]; other site
1006551004029	conserved gate region; other site
1006551004030	putative PBP binding loops; other site
1006551004031	ABC-ATPase subunit interface; other site
1006551004032	2-aminoethylphosphonate transport system permease PhnU; Provisional; Region: PRK15050
1006551004033	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551004034	dimer interface [polypeptide binding]; other site
1006551004035	conserved gate region; other site
1006551004036	putative PBP binding loops; other site
1006551004037	ABC-ATPase subunit interface; other site
1006551004038	2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; Region: PhnT; TIGR03258
1006551004039	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551004040	Walker A/P-loop; other site
1006551004041	ATP binding site [chemical binding]; other site
1006551004042	Q-loop/lid; other site
1006551004043	ABC transporter signature motif; other site
1006551004044	Walker B; other site
1006551004045	D-loop; other site
1006551004046	H-loop/switch region; other site
1006551004047	TOBE domain; Region: TOBE_2; pfam08402
1006551004048	2-aminoethylphosphonate ABC transporter substrate-binding protein; Provisional; Region: PRK15046
1006551004049	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1006551004050	transcriptional regulator protein; Region: phnR; TIGR03337
1006551004051	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551004052	DNA-binding site [nucleotide binding]; DNA binding site
1006551004053	UTRA domain; Region: UTRA; pfam07702
1006551004054	2-aminoethylphosphonate--pyruvate transaminase; Provisional; Region: PRK13479
1006551004055	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1006551004056	catalytic residue [active]
1006551004057	phosphonoacetaldehyde hydrolase; Provisional; Region: PRK13478
1006551004058	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1006551004059	motif II; other site
1006551004060	HAD-hyrolase-like; Region: Hydrolase_like; pfam13242
1006551004061	ribonucleoside transporter; Reviewed; Region: nepI; PRK10213
1006551004062	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551004063	putative substrate translocation pore; other site
1006551004064	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1006551004065	non-specific DNA binding site [nucleotide binding]; other site
1006551004066	salt bridge; other site
1006551004067	sequence-specific DNA binding site [nucleotide binding]; other site
1006551004068	Phage derived protein Gp49-like (DUF891); Region: Gp49; cl01470
1006551004069	Protein of unknown function (DUF1198); Region: DUF1198; pfam06711
1006551004070	sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556
1006551004071	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551004072	putative substrate translocation pore; other site
1006551004073	regulatory protein UhpC; Provisional; Region: PRK11663
1006551004074	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551004075	putative substrate translocation pore; other site
1006551004076	sensory histidine kinase UhpB; Provisional; Region: PRK11644
1006551004077	MASE1; Region: MASE1; pfam05231
1006551004078	Histidine kinase; Region: HisKA_3; pfam07730
1006551004079	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551004080	ATP binding site [chemical binding]; other site
1006551004081	Mg2+ binding site [ion binding]; other site
1006551004082	G-X-G motif; other site
1006551004083	DNA-binding transcriptional activator UhpA; Provisional; Region: PRK10360
1006551004084	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551004085	active site
1006551004086	phosphorylation site [posttranslational modification]
1006551004087	intermolecular recognition site; other site
1006551004088	dimerization interface [polypeptide binding]; other site
1006551004089	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1006551004090	DNA binding residues [nucleotide binding]
1006551004091	dimerization interface [polypeptide binding]; other site
1006551004092	Acetolactate synthase, small (regulatory) subunit [Amino acid transport and metabolism]; Region: IlvH; COG0440
1006551004093	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1006551004094	putative valine binding site [chemical binding]; other site
1006551004095	dimer interface [polypeptide binding]; other site
1006551004096	acetolactate synthase catalytic subunit; Validated; Region: PRK08155
1006551004097	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1006551004098	PYR/PP interface [polypeptide binding]; other site
1006551004099	dimer interface [polypeptide binding]; other site
1006551004100	TPP binding site [chemical binding]; other site
1006551004101	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1006551004102	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1006551004103	TPP-binding site [chemical binding]; other site
1006551004104	dimer interface [polypeptide binding]; other site
1006551004105	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1006551004106	Coenzyme A binding pocket [chemical binding]; other site
1006551004107	phosphonate utilization associated putative membrane protein; Region: phn_DUF6; TIGR03340
1006551004108	multidrug resistance protein D; Provisional; Region: emrD; PRK11652
1006551004109	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551004110	putative substrate translocation pore; other site
1006551004111	DNA-binding transcriptional regulator DsdC; Provisional; Region: PRK10086
1006551004112	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551004113	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
1006551004114	dimerization interface [polypeptide binding]; other site
1006551004115	substrate binding pocket [chemical binding]; other site
1006551004116	permease DsdX; Provisional; Region: PRK09921
1006551004117	gluconate transporter; Region: gntP; TIGR00791
1006551004118	D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine  to pyruvate and ammonia.  D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive...; Region: D-Ser-dehyd; cd06447
1006551004119	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
1006551004120	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1006551004121	catalytic residue [active]
1006551004122	Domain of unknown function (DUF4008); Region: DUF4008; cl14869
1006551004123	Domain of unknown function (DUF202); Region: DUF202; pfam02656
1006551004124	Predicted membrane protein [Function unknown]; Region: COG2149
1006551004125	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
1006551004126	Glycoside Hydrolases Family 4; GlvA- and pagL-like glycosidases; Region: GH4_GlvA_pagL_like; cd05298
1006551004127	NAD binding site [chemical binding]; other site
1006551004128	sugar binding site [chemical binding]; other site
1006551004129	divalent metal binding site [ion binding]; other site
1006551004130	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
1006551004131	dimer interface [polypeptide binding]; other site
1006551004132	PTS system, alpha-glucoside-specific IIBC component; Region: PTS-IIBC-alpha; TIGR02005
1006551004133	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
1006551004134	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1006551004135	active site turn [active]
1006551004136	phosphorylation site [posttranslational modification]
1006551004137	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1006551004138	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551004139	DNA-binding site [nucleotide binding]; DNA binding site
1006551004140	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
1006551004141	putative transporter; Validated; Region: PRK03818
1006551004142	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
1006551004143	TrkA-C domain; Region: TrkA_C; pfam02080
1006551004144	TrkA-C domain; Region: TrkA_C; pfam02080
1006551004145	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
1006551004146	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1006551004147	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
1006551004148	putative dimer interface [polypeptide binding]; other site
1006551004149	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1006551004150	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
1006551004151	putative dimer interface [polypeptide binding]; other site
1006551004152	hypothetical protein; Provisional; Region: PRK11616
1006551004153	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
1006551004154	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551004155	D-galactonate transporter; Region: 2A0114; TIGR00893
1006551004156	putative substrate translocation pore; other site
1006551004157	galactonate dehydratase; Provisional; Region: PRK14017
1006551004158	D-galactonate dehydratase catalyses the dehydration of galactonate to 2-keto-3-deoxygalactnate (KDGal), as part of the D-galactonate nonphosphorolytic catabolic Entner-Doudoroff pathway. D-galactonate dehydratase belongs to the enolase superfamily of...; Region: D-galactonate_dehydratase; cd03325
1006551004159	putative active site pocket [active]
1006551004160	putative metal binding site [ion binding]; other site
1006551004161	2-dehydro-3-deoxy-6-phosphogalactonate aldolase; Reviewed; Region: PRK09140
1006551004162	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1006551004163	active site
1006551004164	intersubunit interface [polypeptide binding]; other site
1006551004165	catalytic residue [active]
1006551004166	2-keto-3-deoxy-galactonokinase [Carbohydrate transport and metabolism]; Region: DgoK; COG3734
1006551004167	2-keto-3-deoxy-galactonokinase; Region: DGOK; pfam05035
1006551004168	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1006551004169	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551004170	DNA-binding site [nucleotide binding]; DNA binding site
1006551004171	FCD domain; Region: FCD; pfam07729
1006551004172	sugar phosphate phosphatase; Provisional; Region: PRK10513
1006551004173	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1006551004174	active site
1006551004175	motif I; other site
1006551004176	motif II; other site
1006551004177	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1006551004178	Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR7; cd08276
1006551004179	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
1006551004180	putative NAD(P) binding site [chemical binding]; other site
1006551004181	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551004182	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551004183	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_6; cd08475
1006551004184	putative effector binding pocket; other site
1006551004185	putative dimerization interface [polypeptide binding]; other site
1006551004186	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
1006551004187	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551004188	Mg2+ binding site [ion binding]; other site
1006551004189	G-X-G motif; other site
1006551004190	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1006551004191	anchoring element; other site
1006551004192	dimer interface [polypeptide binding]; other site
1006551004193	ATP binding site [chemical binding]; other site
1006551004194	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1006551004195	active site
1006551004196	putative metal-binding site [ion binding]; other site
1006551004197	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1006551004198	recF protein; Region: recf; TIGR00611
1006551004199	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551004200	Walker A/P-loop; other site
1006551004201	ATP binding site [chemical binding]; other site
1006551004202	Q-loop/lid; other site
1006551004203	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551004204	ABC transporter signature motif; other site
1006551004205	Walker B; other site
1006551004206	D-loop; other site
1006551004207	H-loop/switch region; other site
1006551004208	DNA polymerase III subunit beta; Validated; Region: PRK05643
1006551004209	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1006551004210	putative DNA binding surface [nucleotide binding]; other site
1006551004211	dimer interface [polypeptide binding]; other site
1006551004212	beta-clamp/clamp loader binding surface; other site
1006551004213	beta-clamp/translesion DNA polymerase binding surface; other site
1006551004214	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1006551004215	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
1006551004216	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1006551004217	Walker A motif; other site
1006551004218	ATP binding site [chemical binding]; other site
1006551004219	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1006551004220	Walker B motif; other site
1006551004221	arginine finger; other site
1006551004222	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1006551004223	DnaA box-binding interface [nucleotide binding]; other site
1006551004224	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
1006551004225	ribonuclease P; Reviewed; Region: rnpA; PRK01732
1006551004226	hypothetical protein; Validated; Region: PRK00041
1006551004227	membrane protein insertase; Provisional; Region: PRK01318
1006551004228	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
1006551004229	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
1006551004230	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1006551004231	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1006551004232	G1 box; other site
1006551004233	GTP/Mg2+ binding site [chemical binding]; other site
1006551004234	Switch I region; other site
1006551004235	G2 box; other site
1006551004236	Switch II region; other site
1006551004237	G3 box; other site
1006551004238	G4 box; other site
1006551004239	G5 box; other site
1006551004240	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
1006551004241	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1006551004242	Coenzyme A binding pocket [chemical binding]; other site
1006551004243	multidrug efflux system protein MdtL; Provisional; Region: PRK10473
1006551004244	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551004245	putative substrate translocation pore; other site
1006551004246	DNA-binding transcriptional regulator YidZ; Provisional; Region: PRK10216
1006551004247	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551004248	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
1006551004249	substrate binding pocket [chemical binding]; other site
1006551004250	dimerization interface [polypeptide binding]; other site
1006551004251	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
1006551004252	Predicted flavoprotein [General function prediction only]; Region: COG0431
1006551004253	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1006551004254	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1006551004255	6-phosphogluconate phosphatase; Provisional; Region: PRK10563
1006551004256	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
1006551004257	active site
1006551004258	motif I; other site
1006551004259	motif II; other site
1006551004260	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1006551004261	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1006551004262	active site
1006551004263	trimer interface [polypeptide binding]; other site
1006551004264	allosteric site; other site
1006551004265	active site lid [active]
1006551004266	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1006551004267	N-terminal Early set domain associated with the catalytic domain of putative esterases; Region: E_set_Esterase_like_N; cd11294
1006551004268	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
1006551004269	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1006551004270	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
1006551004271	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
1006551004272	trimer interface; other site
1006551004273	sugar binding site [chemical binding]; other site
1006551004274	transcriptional regulator PhoU; Provisional; Region: PRK11115
1006551004275	PhoU domain; Region: PhoU; pfam01895
1006551004276	PhoU domain; Region: PhoU; pfam01895
1006551004277	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
1006551004278	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1006551004279	Walker A/P-loop; other site
1006551004280	ATP binding site [chemical binding]; other site
1006551004281	Q-loop/lid; other site
1006551004282	ABC transporter signature motif; other site
1006551004283	Walker B; other site
1006551004284	D-loop; other site
1006551004285	H-loop/switch region; other site
1006551004286	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
1006551004287	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551004288	dimer interface [polypeptide binding]; other site
1006551004289	conserved gate region; other site
1006551004290	putative PBP binding loops; other site
1006551004291	ABC-ATPase subunit interface; other site
1006551004292	phosphate transporter permease subunit PstC; Provisional; Region: pstC; PRK11275
1006551004293	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551004294	dimer interface [polypeptide binding]; other site
1006551004295	conserved gate region; other site
1006551004296	putative PBP binding loops; other site
1006551004297	ABC-ATPase subunit interface; other site
1006551004298	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551004299	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
1006551004300	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
1006551004301	glutaminase active site [active]
1006551004302	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1006551004303	dimer interface [polypeptide binding]; other site
1006551004304	active site
1006551004305	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1006551004306	dimer interface [polypeptide binding]; other site
1006551004307	active site
1006551004308	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
1006551004309	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
1006551004310	Substrate binding site; other site
1006551004311	Mg++ binding site; other site
1006551004312	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
1006551004313	active site
1006551004314	substrate binding site [chemical binding]; other site
1006551004315	CoA binding site [chemical binding]; other site
1006551004316	Right handed beta helix region; Region: Beta_helix; pfam13229
1006551004317	aspartate aminotransferase; Provisional; Region: PRK07568
1006551004318	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
1006551004319	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
1006551004320	gamma subunit interface [polypeptide binding]; other site
1006551004321	epsilon subunit interface [polypeptide binding]; other site
1006551004322	LBP interface [polypeptide binding]; other site
1006551004323	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
1006551004324	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1006551004325	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1006551004326	alpha subunit interaction interface [polypeptide binding]; other site
1006551004327	Walker A motif; other site
1006551004328	ATP binding site [chemical binding]; other site
1006551004329	Walker B motif; other site
1006551004330	inhibitor binding site; inhibition site
1006551004331	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1006551004332	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1006551004333	core domain interface [polypeptide binding]; other site
1006551004334	delta subunit interface [polypeptide binding]; other site
1006551004335	epsilon subunit interface [polypeptide binding]; other site
1006551004336	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
1006551004337	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1006551004338	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
1006551004339	beta subunit interaction interface [polypeptide binding]; other site
1006551004340	Walker A motif; other site
1006551004341	ATP binding site [chemical binding]; other site
1006551004342	Walker B motif; other site
1006551004343	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1006551004344	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
1006551004345	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
1006551004346	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
1006551004347	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
1006551004348	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
1006551004349	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
1006551004350	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
1006551004351	F0F1 ATP synthase subunit I; Validated; Region: PRK08049
1006551004352	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
1006551004353	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551004354	S-adenosylmethionine binding site [chemical binding]; other site
1006551004355	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
1006551004356	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
1006551004357	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1006551004358	FMN-binding protein MioC; Provisional; Region: PRK09004
1006551004359	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
1006551004360	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1006551004361	putative DNA binding site [nucleotide binding]; other site
1006551004362	putative Zn2+ binding site [ion binding]; other site
1006551004363	AsnC family; Region: AsnC_trans_reg; pfam01037
1006551004364	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
1006551004365	dimer interface [polypeptide binding]; other site
1006551004366	active site
1006551004367	hypothetical protein; Provisional; Region: yieM; PRK10997
1006551004368	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
1006551004369	metal ion-dependent adhesion site (MIDAS); other site
1006551004370	regulatory ATPase RavA; Provisional; Region: PRK13531
1006551004371	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1006551004372	Walker A motif; other site
1006551004373	ATP binding site [chemical binding]; other site
1006551004374	Walker B motif; other site
1006551004375	arginine finger; other site
1006551004376	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
1006551004377	potassium transport protein Kup; Provisional; Region: trkD; PRK10745
1006551004378	potassium uptake protein; Region: kup; TIGR00794
1006551004379	D-ribose pyranase; Provisional; Region: PRK11797
1006551004380	D-ribose transporter ATP binding protein; Provisional; Region: PRK10762
1006551004381	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1006551004382	Walker A/P-loop; other site
1006551004383	ATP binding site [chemical binding]; other site
1006551004384	Q-loop/lid; other site
1006551004385	ABC transporter signature motif; other site
1006551004386	Walker B; other site
1006551004387	D-loop; other site
1006551004388	H-loop/switch region; other site
1006551004389	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1006551004390	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1006551004391	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1006551004392	TM-ABC transporter signature motif; other site
1006551004393	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
1006551004394	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
1006551004395	ligand binding site [chemical binding]; other site
1006551004396	dimerization interface [polypeptide binding]; other site
1006551004397	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1006551004398	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1006551004399	substrate binding site [chemical binding]; other site
1006551004400	dimer interface [polypeptide binding]; other site
1006551004401	ATP binding site [chemical binding]; other site
1006551004402	transcriptional repressor RbsR; Provisional; Region: PRK10423
1006551004403	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1006551004404	DNA binding site [nucleotide binding]
1006551004405	domain linker motif; other site
1006551004406	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
1006551004407	dimerization interface [polypeptide binding]; other site
1006551004408	ligand binding site [chemical binding]; other site
1006551004409	putative transporter; Provisional; Region: PRK10504
1006551004410	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551004411	putative substrate translocation pore; other site
1006551004412	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551004413	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1006551004414	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551004415	DNA-binding site [nucleotide binding]; DNA binding site
1006551004416	FCD domain; Region: FCD; pfam07729
1006551004417	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
1006551004418	Walker A motif; other site
1006551004419	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
1006551004420	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
1006551004421	GTP binding site; other site
1006551004422	Protein of unknown function (DUF1040); Region: DUF1040; pfam06288
1006551004423	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
1006551004424	serine/threonine protein kinase; Provisional; Region: PRK11768
1006551004425	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
1006551004426	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1006551004427	catalytic residues [active]
1006551004428	hinge region; other site
1006551004429	alpha helical domain; other site
1006551004430	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1006551004431	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Region: LPLAT_LCLAT1-like; cd07990
1006551004432	putative acyl-acceptor binding pocket; other site
1006551004433	DNA polymerase I; Provisional; Region: PRK05755
1006551004434	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1006551004435	active site
1006551004436	metal binding site 1 [ion binding]; metal-binding site
1006551004437	putative 5' ssDNA interaction site; other site
1006551004438	metal binding site 3; metal-binding site
1006551004439	metal binding site 2 [ion binding]; metal-binding site
1006551004440	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1006551004441	putative DNA binding site [nucleotide binding]; other site
1006551004442	putative metal binding site [ion binding]; other site
1006551004443	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
1006551004444	active site
1006551004445	catalytic site [active]
1006551004446	substrate binding site [chemical binding]; other site
1006551004447	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
1006551004448	active site
1006551004449	DNA binding site [nucleotide binding]
1006551004450	catalytic site [active]
1006551004451	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
1006551004452	G1 box; other site
1006551004453	GTP/Mg2+ binding site [chemical binding]; other site
1006551004454	Switch I region; other site
1006551004455	G2 box; other site
1006551004456	G3 box; other site
1006551004457	Switch II region; other site
1006551004458	G4 box; other site
1006551004459	G5 box; other site
1006551004460	Der GTPase activator; Provisional; Region: PRK05244
1006551004461	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
1006551004462	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1006551004463	FeS/SAM binding site; other site
1006551004464	HemN C-terminal domain; Region: HemN_C; pfam06969
1006551004465	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
1006551004466	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551004467	active site
1006551004468	phosphorylation site [posttranslational modification]
1006551004469	intermolecular recognition site; other site
1006551004470	dimerization interface [polypeptide binding]; other site
1006551004471	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1006551004472	Walker A motif; other site
1006551004473	ATP binding site [chemical binding]; other site
1006551004474	Walker B motif; other site
1006551004475	arginine finger; other site
1006551004476	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1006551004477	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
1006551004478	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
1006551004479	putative active site [active]
1006551004480	heme pocket [chemical binding]; other site
1006551004481	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1006551004482	dimer interface [polypeptide binding]; other site
1006551004483	phosphorylation site [posttranslational modification]
1006551004484	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551004485	ATP binding site [chemical binding]; other site
1006551004486	Mg2+ binding site [ion binding]; other site
1006551004487	G-X-G motif; other site
1006551004488	glutamine synthetase; Provisional; Region: glnA; PRK09469
1006551004489	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
1006551004490	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1006551004491	GTP-binding protein; Provisional; Region: PRK10218
1006551004492	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
1006551004493	G1 box; other site
1006551004494	putative GEF interaction site [polypeptide binding]; other site
1006551004495	GTP/Mg2+ binding site [chemical binding]; other site
1006551004496	Switch I region; other site
1006551004497	G2 box; other site
1006551004498	G3 box; other site
1006551004499	Switch II region; other site
1006551004500	G4 box; other site
1006551004501	G5 box; other site
1006551004502	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
1006551004503	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
1006551004504	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
1006551004505	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1006551004506	motif II; other site
1006551004507	hypothetical protein; Reviewed; Region: PRK01637
1006551004508	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
1006551004509	putative active site [active]
1006551004510	dimerization interface [polypeptide binding]; other site
1006551004511	putative tRNAtyr binding site [nucleotide binding]; other site
1006551004512	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1006551004513	Coenzyme A binding pocket [chemical binding]; other site
1006551004514	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
1006551004515	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1006551004516	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1006551004517	substrate binding pocket [chemical binding]; other site
1006551004518	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
1006551004519	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
1006551004520	formate dehydrogenase-O subunit gamma; Provisional; Region: PRK10639
1006551004521	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
1006551004522	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
1006551004523	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
1006551004524	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1006551004525	molybdopterin cofactor binding site; other site
1006551004526	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
1006551004527	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
1006551004528	molybdopterin cofactor binding site; other site
1006551004529	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1006551004530	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
1006551004531	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases; Region: PFK; cl00204
1006551004532	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
1006551004533	active site
1006551004534	ADP/pyrophosphate binding site [chemical binding]; other site
1006551004535	dimerization interface [polypeptide binding]; other site
1006551004536	allosteric effector site; other site
1006551004537	fructose-1,6-bisphosphate binding site; other site
1006551004538	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1006551004539	active site
1006551004540	P-loop; other site
1006551004541	phosphorylation site [posttranslational modification]
1006551004542	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: PRK12997
1006551004543	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1006551004544	intersubunit interface [polypeptide binding]; other site
1006551004545	active site
1006551004546	zinc binding site [ion binding]; other site
1006551004547	Na+ binding site [ion binding]; other site
1006551004548	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1006551004549	active site
1006551004550	phosphorylation site [posttranslational modification]
1006551004551	AAA domain; Region: AAA_33; pfam13671
1006551004552	AAA domain; Region: AAA_17; pfam13207
1006551004553	Branched-chain amino acid transport protein (AzlD); Region: AzlD; pfam05437
1006551004554	AzlC protein; Region: AzlC; cl00570
1006551004555	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1006551004556	non-specific DNA binding site [nucleotide binding]; other site
1006551004557	salt bridge; other site
1006551004558	sequence-specific DNA binding site [nucleotide binding]; other site
1006551004559	Cupin domain; Region: Cupin_2; cl17218
1006551004560	Acetyltransferase (GNAT) domain; Region: Acetyltransf_4; pfam13420
1006551004561	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1006551004562	Coenzyme A binding pocket [chemical binding]; other site
1006551004563	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1006551004564	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1006551004565	CoA binding site [chemical binding]; other site
1006551004566	Acyl-CoA reductase (LuxC); Region: LuxC; pfam05893
1006551004567	Acyl-CoA reductase LuxC; Region: ALDH_Acyl-CoA-Red_LuxC; cd07080
1006551004568	putative catalytic cysteine [active]
1006551004569	Coenzyme F390 synthetase [Coenzyme metabolism]; Region: PaaK; COG1541
1006551004570	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1006551004571	active site
1006551004572	AMP binding site [chemical binding]; other site
1006551004573	acyl-activating enzyme (AAE) consensus motif; other site
1006551004574	CoA binding site [chemical binding]; other site
1006551004575	Acyl-protein synthetase, LuxE; Region: LuxE; pfam04443
1006551004576	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
1006551004577	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cl17904
1006551004578	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1006551004579	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1006551004580	DNA binding site [nucleotide binding]
1006551004581	domain linker motif; other site
1006551004582	Ligand-binding domain of DNA transcription repressors specific for raffinose (RafR) and alpha-glucosides (AglR) which are members of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_AglR_RafR_like; cd06271
1006551004583	ligand binding site [chemical binding]; other site
1006551004584	Alpha-galactosidase [Carbohydrate transport and metabolism]; Region: GalA; COG3345
1006551004585	Melibiase; Region: Melibiase; pfam02065
1006551004586	galactoside permease; Reviewed; Region: lacY; PRK09528
1006551004587	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551004588	putative substrate translocation pore; other site
1006551004589	galactoside O-acetyltransferase; Reviewed; Region: lacA; PRK09527
1006551004590	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
1006551004591	active site
1006551004592	substrate binding site [chemical binding]; other site
1006551004593	trimer interface [polypeptide binding]; other site
1006551004594	CoA binding site [chemical binding]; other site
1006551004595	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
1006551004596	Fimbrial protein; Region: Fimbrial; cl01416
1006551004597	Fimbrial protein; Region: Fimbrial; cl01416
1006551004598	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1006551004599	fimbrial assembly chaperone SthB; Provisional; Region: PRK15295
1006551004600	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1006551004601	outer membrane usher protein; Provisional; Region: PRK15193
1006551004602	PapC N-terminal domain; Region: PapC_N; pfam13954
1006551004603	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1006551004604	PapC C-terminal domain; Region: PapC_C; pfam13953
1006551004605	Fimbrial protein; Region: Fimbrial; cl01416
1006551004606	Fimbrial protein; Region: Fimbrial; cl01416
1006551004607	Fimbrial protein; Region: Fimbrial; cl01416
1006551004608	Fimbrial protein; Region: Fimbrial; cl01416
1006551004609	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1006551004610	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1006551004611	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1006551004612	O-Antigen ligase; Region: Wzy_C; pfam04932
1006551004613	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
1006551004614	Domain of unknown function (DUF3366); Region: DUF3366; pfam11846
1006551004615	Conserved TM helix; Region: TM_helix; pfam05552
1006551004616	mechanosensitive channel MscS; Provisional; Region: PRK10334
1006551004617	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1006551004618	Protein of unknown function (DUF1375); Region: DUF1375; cl11456
1006551004619	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1006551004620	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1006551004621	DNA binding residues [nucleotide binding]
1006551004622	dimerization interface [polypeptide binding]; other site
1006551004623	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1006551004624	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1006551004625	DNA binding site [nucleotide binding]
1006551004626	domain linker motif; other site
1006551004627	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1006551004628	dimerization interface [polypeptide binding]; other site
1006551004629	ligand binding site [chemical binding]; other site
1006551004630	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1006551004631	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551004632	putative substrate translocation pore; other site
1006551004633	Beta-fructosidases (levanase/invertase) [Carbohydrate transport and metabolism]; Region: SacC; COG1621
1006551004634	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
1006551004635	substrate binding [chemical binding]; other site
1006551004636	active site
1006551004637	Right handed beta helix region; Region: Beta_helix; pfam13229
1006551004638	L-rhamnose 1-epimerase; Region: YiiL_rotase; TIGR02625
1006551004639	lactaldehyde reductase; Region: lactal_redase; TIGR02638
1006551004640	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
1006551004641	dimer interface [polypeptide binding]; other site
1006551004642	active site
1006551004643	metal binding site [ion binding]; metal-binding site
1006551004644	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1006551004645	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1006551004646	TM-ABC transporter signature motif; other site
1006551004647	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1006551004648	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1006551004649	TM-ABC transporter signature motif; other site
1006551004650	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1006551004651	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1006551004652	Walker A/P-loop; other site
1006551004653	ATP binding site [chemical binding]; other site
1006551004654	Q-loop/lid; other site
1006551004655	ABC transporter signature motif; other site
1006551004656	Walker B; other site
1006551004657	D-loop; other site
1006551004658	H-loop/switch region; other site
1006551004659	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1006551004660	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
1006551004661	rhamnose ABC transporter, rhamnose-binding protein; Region: RhaS; TIGR02637
1006551004662	ligand binding site [chemical binding]; other site
1006551004663	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1006551004664	intersubunit interface [polypeptide binding]; other site
1006551004665	active site
1006551004666	Zn2+ binding site [ion binding]; other site
1006551004667	L-rhamnose isomerase; Provisional; Region: PRK01076
1006551004668	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
1006551004669	N- and C-terminal domain interface [polypeptide binding]; other site
1006551004670	active site
1006551004671	putative catalytic site [active]
1006551004672	metal binding site [ion binding]; metal-binding site
1006551004673	ATP binding site [chemical binding]; other site
1006551004674	rhamnulokinase; Provisional; Region: rhaB; PRK10640
1006551004675	carbohydrate binding site [chemical binding]; other site
1006551004676	transcriptional activator RhaS; Provisional; Region: PRK13503
1006551004677	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1006551004678	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551004679	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551004680	transcriptional activator RhaR; Provisional; Region: PRK13502
1006551004681	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1006551004682	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551004683	L-rhamnose-proton symport protein (RhaT); Region: RhaT; cl05728
1006551004684	RhaT L-rhamnose-proton symporter family protein; Region: RhaT; TIGR00776
1006551004685	superoxide dismutase; Provisional; Region: PRK10925
1006551004686	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1006551004687	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1006551004688	6-N-hydroxylaminopurine resistance protein; Provisional; Region: PRK11536
1006551004689	MOSC domain; Region: MOSC; pfam03473
1006551004690	3-alpha domain; Region: 3-alpha; pfam03475
1006551004691	two-component sensor protein; Provisional; Region: cpxA; PRK09470
1006551004692	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1006551004693	dimerization interface [polypeptide binding]; other site
1006551004694	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1006551004695	dimer interface [polypeptide binding]; other site
1006551004696	phosphorylation site [posttranslational modification]
1006551004697	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551004698	ATP binding site [chemical binding]; other site
1006551004699	Mg2+ binding site [ion binding]; other site
1006551004700	G-X-G motif; other site
1006551004701	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
1006551004702	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551004703	active site
1006551004704	intermolecular recognition site; other site
1006551004705	dimerization interface [polypeptide binding]; other site
1006551004706	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1006551004707	DNA binding site [nucleotide binding]
1006551004708	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1006551004709	dimer interface [polypeptide binding]; other site
1006551004710	ferrous iron efflux protein F; Reviewed; Region: fieF; PRK09509
1006551004711	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1006551004712	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
1006551004713	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
1006551004714	active site
1006551004715	ADP/pyrophosphate binding site [chemical binding]; other site
1006551004716	dimerization interface [polypeptide binding]; other site
1006551004717	allosteric effector site; other site
1006551004718	fructose-1,6-bisphosphate binding site; other site
1006551004719	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
1006551004720	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Region: menA; TIGR00751
1006551004721	UbiA prenyltransferase family; Region: UbiA; pfam01040
1006551004722	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
1006551004723	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1006551004724	Walker A motif; other site
1006551004725	ATP binding site [chemical binding]; other site
1006551004726	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
1006551004727	Walker B motif; other site
1006551004728	arginine finger; other site
1006551004729	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1006551004730	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
1006551004731	active site
1006551004732	HslU subunit interaction site [polypeptide binding]; other site
1006551004733	essential cell division protein FtsN; Provisional; Region: PRK10927
1006551004734	cell division protein FtsN; Provisional; Region: PRK12757
1006551004735	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1006551004736	DNA binding site [nucleotide binding]
1006551004737	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
1006551004738	domain linker motif; other site
1006551004739	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
1006551004740	dimerization interface [polypeptide binding]; other site
1006551004741	ligand binding site [chemical binding]; other site
1006551004742	primosome assembly protein PriA; Validated; Region: PRK05580
1006551004743	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1006551004744	ATP binding site [chemical binding]; other site
1006551004745	putative Mg++ binding site [ion binding]; other site
1006551004746	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1006551004747	ATP-binding site [chemical binding]; other site
1006551004748	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
1006551004749	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
1006551004750	dimerization interface [polypeptide binding]; other site
1006551004751	DNA binding site [nucleotide binding]
1006551004752	corepressor binding sites; other site
1006551004753	cystathionine gamma-synthase; Provisional; Region: PRK08045
1006551004754	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1006551004755	homodimer interface [polypeptide binding]; other site
1006551004756	substrate-cofactor binding pocket; other site
1006551004757	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551004758	catalytic residue [active]
1006551004759	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
1006551004760	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
1006551004761	putative catalytic residues [active]
1006551004762	putative nucleotide binding site [chemical binding]; other site
1006551004763	putative aspartate binding site [chemical binding]; other site
1006551004764	ACT domains C-terminal to the catalytic domain of aspartokinase (AK; 4-L-aspartate-4-phosphotransferase); Region: ACT_AK-like_2; cd04892
1006551004765	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1006551004766	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1006551004767	Carboxymuconolactone decarboxylase family; Region: CMD; cl00460
1006551004768	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
1006551004769	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551004770	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
1006551004771	dimerization interface [polypeptide binding]; other site
1006551004772	substrate binding pocket [chemical binding]; other site
1006551004773	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
1006551004774	FAD binding site [chemical binding]; other site
1006551004775	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1006551004776	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1006551004777	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1006551004778	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1006551004779	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
1006551004780	dimer interface [polypeptide binding]; other site
1006551004781	active site
1006551004782	metal binding site [ion binding]; metal-binding site
1006551004783	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
1006551004784	active site
1006551004785	intersubunit interactions; other site
1006551004786	catalytic residue [active]
1006551004787	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1006551004788	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551004789	zinc/cadmium-binding protein; Provisional; Region: PRK10306
1006551004790	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
1006551004791	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
1006551004792	acetylornithine deacetylase; Provisional; Region: PRK05111
1006551004793	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
1006551004794	metal binding site [ion binding]; metal-binding site
1006551004795	putative dimer interface [polypeptide binding]; other site
1006551004796	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
1006551004797	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1006551004798	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
1006551004799	nucleotide binding site [chemical binding]; other site
1006551004800	N-acetyl-L-glutamate binding site [chemical binding]; other site
1006551004801	argininosuccinate lyase; Provisional; Region: PRK04833
1006551004802	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
1006551004803	active sites [active]
1006551004804	tetramer interface [polypeptide binding]; other site
1006551004805	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
1006551004806	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551004807	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
1006551004808	dimerization interface [polypeptide binding]; other site
1006551004809	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
1006551004810	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1006551004811	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1006551004812	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
1006551004813	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1006551004814	hypothetical protein; Provisional; Region: PRK11056
1006551004815	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
1006551004816	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551004817	S-adenosylmethionine binding site [chemical binding]; other site
1006551004818	vitamin B12/cobalamin outer membrane transporter; Provisional; Region: btuB; PRK10641
1006551004819	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1006551004820	N-terminal plug; other site
1006551004821	ligand-binding site [chemical binding]; other site
1006551004822	glutamate racemase; Provisional; Region: PRK00865
1006551004823	transcriptional regulator HdfR; Provisional; Region: PRK03601
1006551004824	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551004825	LysR substrate binding domain; Region: LysR_substrate; pfam03466
1006551004826	hypothetical protein; Provisional; Region: PRK11027
1006551004827	putative ATP-dependent protease; Provisional; Region: PRK09862
1006551004828	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1006551004829	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1006551004830	Walker A motif; other site
1006551004831	ATP binding site [chemical binding]; other site
1006551004832	Walker B motif; other site
1006551004833	arginine finger; other site
1006551004834	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
1006551004835	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
1006551004836	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1006551004837	PYR/PP interface [polypeptide binding]; other site
1006551004838	dimer interface [polypeptide binding]; other site
1006551004839	TPP binding site [chemical binding]; other site
1006551004840	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1006551004841	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1006551004842	TPP-binding site [chemical binding]; other site
1006551004843	dimer interface [polypeptide binding]; other site
1006551004844	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
1006551004845	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1006551004846	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
1006551004847	homodimer interface [polypeptide binding]; other site
1006551004848	substrate-cofactor binding pocket; other site
1006551004849	catalytic residue [active]
1006551004850	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
1006551004851	threonine dehydratase; Reviewed; Region: PRK09224
1006551004852	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1006551004853	tetramer interface [polypeptide binding]; other site
1006551004854	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551004855	catalytic residue [active]
1006551004856	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
1006551004857	putative Ile/Val binding site [chemical binding]; other site
1006551004858	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
1006551004859	putative Ile/Val binding site [chemical binding]; other site
1006551004860	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551004861	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
1006551004862	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
1006551004863	putative dimerization interface [polypeptide binding]; other site
1006551004864	ketol-acid reductoisomerase; Validated; Region: PRK05225
1006551004865	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
1006551004866	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1006551004867	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1006551004868	peptidyl-prolyl cis-trans isomerase C; Provisional; Region: PRK15441
1006551004869	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
1006551004870	PPIC-type PPIASE domain; Region: Rotamase_2; cl08278
1006551004871	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
1006551004872	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1006551004873	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1006551004874	ligand binding site [chemical binding]; other site
1006551004875	flexible hinge region; other site
1006551004876	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
1006551004877	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
1006551004878	uridine phosphorylase; Provisional; Region: PRK11178
1006551004879	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
1006551004880	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
1006551004881	Part of AAA domain; Region: AAA_19; pfam13245
1006551004882	Family description; Region: UvrD_C_2; pfam13538
1006551004883	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1006551004884	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
1006551004885	substrate binding site [chemical binding]; other site
1006551004886	ATP binding site [chemical binding]; other site
1006551004887	potential frameshift: common BLAST hit: gi|269139149|ref|YP_003295850.1| purine-cytosine permease
1006551004888	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
1006551004889	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1006551004890	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551004891	DNA-binding site [nucleotide binding]; DNA binding site
1006551004892	UTRA domain; Region: UTRA; pfam07702
1006551004893	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
1006551004894	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1006551004895	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
1006551004896	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1006551004897	ATP binding site [chemical binding]; other site
1006551004898	Mg++ binding site [ion binding]; other site
1006551004899	motif III; other site
1006551004900	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1006551004901	nucleotide binding region [chemical binding]; other site
1006551004902	ATP-binding site [chemical binding]; other site
1006551004903	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1006551004904	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1006551004905	catalytic residues [active]
1006551004906	transcription termination factor Rho; Provisional; Region: rho; PRK09376
1006551004907	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
1006551004908	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
1006551004909	RNA binding site [nucleotide binding]; other site
1006551004910	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
1006551004911	multimer interface [polypeptide binding]; other site
1006551004912	Walker A motif; other site
1006551004913	ATP binding site [chemical binding]; other site
1006551004914	Walker B motif; other site
1006551004915	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Provisional; Region: PRK15119
1006551004916	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
1006551004917	Mg++ binding site [ion binding]; other site
1006551004918	putative catalytic motif [active]
1006551004919	substrate binding site [chemical binding]; other site
1006551004920	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
1006551004921	Chain length determinant protein; Region: Wzz; pfam02706
1006551004922	UDP-N-acetylglucosamine 2-epimerase; Region: wecB; TIGR00236
1006551004923	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1006551004924	active site
1006551004925	homodimer interface [polypeptide binding]; other site
1006551004926	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
1006551004927	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1006551004928	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1006551004929	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1006551004930	TDP-fucosamine acetyltransferase; Provisional; Region: PRK10975
1006551004931	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1006551004932	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1006551004933	inhibitor-cofactor binding pocket; inhibition site
1006551004934	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551004935	catalytic residue [active]
1006551004936	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1006551004937	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
1006551004938	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429
1006551004939	putative common antigen polymerase; Provisional; Region: PRK02975
1006551004940	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
1006551004941	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
1006551004942	putative transport protein YifK; Provisional; Region: PRK10746
1006551004943	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
1006551004944	HemY protein N-terminus; Region: HemY_N; pfam07219
1006551004945	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1006551004946	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
1006551004947	Uncharacterized enzyme of heme biosynthesis [Coenzyme metabolism]; Region: HemX; COG2959
1006551004948	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
1006551004949	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1006551004950	active site
1006551004951	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
1006551004952	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
1006551004953	domain interfaces; other site
1006551004954	active site
1006551004955	Adenylate cyclase [Nucleotide transport and metabolism]; Region: CyaA; COG3072
1006551004956	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
1006551004957	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
1006551004958	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
1006551004959	putative iron binding site [ion binding]; other site
1006551004960	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1006551004961	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551004962	putative substrate translocation pore; other site
1006551004963	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1006551004964	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551004965	putative substrate translocation pore; other site
1006551004966	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
1006551004967	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
1006551004968	active site
1006551004969	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1006551004970	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551004971	DNA-binding site [nucleotide binding]; DNA binding site
1006551004972	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1006551004973	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551004974	homodimer interface [polypeptide binding]; other site
1006551004975	catalytic residue [active]
1006551004976	Prokaryotic lipoprotein-attachment site; Region: LPAM_2; cl02361
1006551004977	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
1006551004978	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1006551004979	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1006551004980	hypothetical protein; Provisional; Region: PRK10963
1006551004981	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
1006551004982	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1006551004983	active site
1006551004984	Int/Topo IB signature motif; other site
1006551004985	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
1006551004986	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1006551004987	motif II; other site
1006551004988	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
1006551004989	Part of AAA domain; Region: AAA_19; pfam13245
1006551004990	Family description; Region: UvrD_C_2; pfam13538
1006551004991	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1006551004992	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
1006551004993	Cl binding site [ion binding]; other site
1006551004994	oligomer interface [polypeptide binding]; other site
1006551004995	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
1006551004996	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1006551004997	CoenzymeA binding site [chemical binding]; other site
1006551004998	subunit interaction site [polypeptide binding]; other site
1006551004999	PHB binding site; other site
1006551005000	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
1006551005001	dimerization interface [polypeptide binding]; other site
1006551005002	substrate binding site [chemical binding]; other site
1006551005003	active site
1006551005004	calcium binding site [ion binding]; other site
1006551005005	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
1006551005006	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1006551005007	ATP binding site [chemical binding]; other site
1006551005008	putative Mg++ binding site [ion binding]; other site
1006551005009	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1006551005010	nucleotide binding region [chemical binding]; other site
1006551005011	ATP-binding site [chemical binding]; other site
1006551005012	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
1006551005013	Helicase and RNase D C-terminal; Region: HRDC; smart00341
1006551005014	threonine efflux system; Provisional; Region: PRK10229
1006551005015	Uncharacterized conserved protein [Function unknown]; Region: COG5464
1006551005016	homoserine/homoserine lactone efflux protein; Provisional; Region: rhtB; PRK10520
1006551005017	lysophospholipase L2; Provisional; Region: PRK10749
1006551005018	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1006551005019	putative hydrolase; Provisional; Region: PRK10976
1006551005020	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1006551005021	active site
1006551005022	motif I; other site
1006551005023	motif II; other site
1006551005024	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1006551005025	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1006551005026	EamA-like transporter family; Region: EamA; pfam00892
1006551005027	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
1006551005028	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551005029	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
1006551005030	putative dimerization interface [polypeptide binding]; other site
1006551005031	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
1006551005032	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
1006551005033	THF binding site; other site
1006551005034	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1006551005035	substrate binding site [chemical binding]; other site
1006551005036	THF binding site; other site
1006551005037	zinc-binding site [ion binding]; other site
1006551005038	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
1006551005039	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551005040	substrate binding pocket [chemical binding]; other site
1006551005041	membrane-bound complex binding site; other site
1006551005042	hinge residues; other site
1006551005043	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
1006551005044	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1006551005045	uridine phosphorylase; Provisional; Region: PRK11178
1006551005046	uridine phosphorylase; Region: Uridine-psphlse; TIGR01718
1006551005047	DNA recombination protein RmuC; Provisional; Region: PRK10361
1006551005048	RmuC family; Region: RmuC; pfam02646
1006551005049	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
1006551005050	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551005051	S-adenosylmethionine binding site [chemical binding]; other site
1006551005052	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4627
1006551005053	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
1006551005054	SCP-2 sterol transfer family; Region: SCP2; pfam02036
1006551005055	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
1006551005056	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
1006551005057	twin arginine translocase protein A; Provisional; Region: tatA; PRK03554
1006551005058	sec-independent translocase; Provisional; Region: PRK01770
1006551005059	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
1006551005060	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1006551005061	active site
1006551005062	N-Utilization Substance G (NusG) N-terminal (NGN) domain Superfamily; Region: NGN; cl02766
1006551005063	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
1006551005064	3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922
1006551005065	FMN reductase; Validated; Region: fre; PRK08051
1006551005066	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
1006551005067	FAD binding pocket [chemical binding]; other site
1006551005068	FAD binding motif [chemical binding]; other site
1006551005069	phosphate binding motif [ion binding]; other site
1006551005070	beta-alpha-beta structure motif; other site
1006551005071	NAD binding pocket [chemical binding]; other site
1006551005072	3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947
1006551005073	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1006551005074	dimer interface [polypeptide binding]; other site
1006551005075	active site
1006551005076	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
1006551005077	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1006551005078	substrate binding site [chemical binding]; other site
1006551005079	oxyanion hole (OAH) forming residues; other site
1006551005080	trimer interface [polypeptide binding]; other site
1006551005081	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1006551005082	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1006551005083	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1006551005084	proline dipeptidase; Provisional; Region: PRK13607
1006551005085	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
1006551005086	active site
1006551005087	hypothetical protein; Provisional; Region: PRK11568
1006551005088	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
1006551005089	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
1006551005090	potassium transporter; Provisional; Region: PRK10750
1006551005091	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
1006551005092	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
1006551005093	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
1006551005094	FAD binding domain; Region: FAD_binding_4; pfam01565
1006551005095	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1006551005096	Biotin operon repressor [Transcription]; Region: BirA; COG1654
1006551005097	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
1006551005098	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
1006551005099	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
1006551005100	pantothenate kinase; Provisional; Region: PRK05439
1006551005101	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
1006551005102	ATP-binding site [chemical binding]; other site
1006551005103	CoA-binding site [chemical binding]; other site
1006551005104	Mg2+-binding site [ion binding]; other site
1006551005105	elongation factor Tu; Reviewed; Region: PRK00049
1006551005106	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1006551005107	G1 box; other site
1006551005108	GEF interaction site [polypeptide binding]; other site
1006551005109	GTP/Mg2+ binding site [chemical binding]; other site
1006551005110	Switch I region; other site
1006551005111	G2 box; other site
1006551005112	G3 box; other site
1006551005113	Switch II region; other site
1006551005114	G4 box; other site
1006551005115	G5 box; other site
1006551005116	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1006551005117	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1006551005118	Antibiotic Binding Site [chemical binding]; other site
1006551005119	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
1006551005120	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1006551005121	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1006551005122	putative homodimer interface [polypeptide binding]; other site
1006551005123	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1006551005124	heterodimer interface [polypeptide binding]; other site
1006551005125	homodimer interface [polypeptide binding]; other site
1006551005126	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1006551005127	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1006551005128	23S rRNA interface [nucleotide binding]; other site
1006551005129	L7/L12 interface [polypeptide binding]; other site
1006551005130	putative thiostrepton binding site; other site
1006551005131	L25 interface [polypeptide binding]; other site
1006551005132	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1006551005133	mRNA/rRNA interface [nucleotide binding]; other site
1006551005134	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1006551005135	23S rRNA interface [nucleotide binding]; other site
1006551005136	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1006551005137	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1006551005138	core dimer interface [polypeptide binding]; other site
1006551005139	peripheral dimer interface [polypeptide binding]; other site
1006551005140	L10 interface [polypeptide binding]; other site
1006551005141	L11 interface [polypeptide binding]; other site
1006551005142	putative EF-Tu interaction site [polypeptide binding]; other site
1006551005143	putative EF-G interaction site [polypeptide binding]; other site
1006551005144	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
1006551005145	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1006551005146	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
1006551005147	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1006551005148	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
1006551005149	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1006551005150	RPB3 interaction site [polypeptide binding]; other site
1006551005151	RPB1 interaction site [polypeptide binding]; other site
1006551005152	RPB11 interaction site [polypeptide binding]; other site
1006551005153	RPB10 interaction site [polypeptide binding]; other site
1006551005154	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
1006551005155	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
1006551005156	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
1006551005157	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
1006551005158	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
1006551005159	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
1006551005160	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1006551005161	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
1006551005162	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1006551005163	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1006551005164	DNA binding site [nucleotide binding]
1006551005165	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1006551005166	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1006551005167	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
1006551005168	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1006551005169	methionine cluster; other site
1006551005170	active site
1006551005171	phosphorylation site [posttranslational modification]
1006551005172	metal binding site [ion binding]; metal-binding site
1006551005173	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1006551005174	active site
1006551005175	P-loop; other site
1006551005176	phosphorylation site [posttranslational modification]
1006551005177	Cache domain; Region: Cache_1; pfam02743
1006551005178	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1006551005179	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1006551005180	metal binding site [ion binding]; metal-binding site
1006551005181	active site
1006551005182	I-site; other site
1006551005183	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
1006551005184	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1006551005185	FeS/SAM binding site; other site
1006551005186	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
1006551005187	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
1006551005188	ThiS interaction site; other site
1006551005189	putative active site [active]
1006551005190	tetramer interface [polypeptide binding]; other site
1006551005191	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
1006551005192	thiS-thiF/thiG interaction site; other site
1006551005193	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1006551005194	thiazole biosynthesis adenylyltransferase ThiF, E. coli subfamily; Region: adenyl_thiF; TIGR02356
1006551005195	ATP binding site [chemical binding]; other site
1006551005196	substrate interface [chemical binding]; other site
1006551005197	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1006551005198	thiamine phosphate binding site [chemical binding]; other site
1006551005199	active site
1006551005200	pyrophosphate binding site [ion binding]; other site
1006551005201	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
1006551005202	ThiC-associated domain; Region: ThiC-associated; pfam13667
1006551005203	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
1006551005204	anti-RNA polymerase sigma 70 factor; Provisional; Region: PRK11718
1006551005205	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
1006551005206	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
1006551005207	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
1006551005208	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
1006551005209	putative NADH binding site [chemical binding]; other site
1006551005210	putative active site [active]
1006551005211	nudix motif; other site
1006551005212	putative metal binding site [ion binding]; other site
1006551005213	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
1006551005214	substrate binding site [chemical binding]; other site
1006551005215	active site
1006551005216	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
1006551005217	Active_site [active]
1006551005218	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
1006551005219	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1006551005220	IHF dimer interface [polypeptide binding]; other site
1006551005221	IHF - DNA interface [nucleotide binding]; other site
1006551005222	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
1006551005223	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1006551005224	dimer interface [polypeptide binding]; other site
1006551005225	sensor protein ZraS; Provisional; Region: PRK10364
1006551005226	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1006551005227	dimer interface [polypeptide binding]; other site
1006551005228	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551005229	ATP binding site [chemical binding]; other site
1006551005230	Mg2+ binding site [ion binding]; other site
1006551005231	G-X-G motif; other site
1006551005232	transcriptional regulatory protein ZraR; Provisional; Region: PRK10365
1006551005233	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551005234	active site
1006551005235	phosphorylation site [posttranslational modification]
1006551005236	intermolecular recognition site; other site
1006551005237	dimerization interface [polypeptide binding]; other site
1006551005238	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1006551005239	Walker A motif; other site
1006551005240	ATP binding site [chemical binding]; other site
1006551005241	Walker B motif; other site
1006551005242	arginine finger; other site
1006551005243	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1006551005244	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
1006551005245	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
1006551005246	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
1006551005247	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
1006551005248	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
1006551005249	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
1006551005250	purine monophosphate binding site [chemical binding]; other site
1006551005251	dimer interface [polypeptide binding]; other site
1006551005252	putative catalytic residues [active]
1006551005253	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
1006551005254	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
1006551005255	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1006551005256	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1006551005257	Coenzyme A binding pocket [chemical binding]; other site
1006551005258	homoserine O-succinyltransferase; Provisional; Region: PRK05368
1006551005259	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
1006551005260	proposed active site lysine [active]
1006551005261	conserved cys residue [active]
1006551005262	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
1006551005263	malate synthase A; Region: malate_syn_A; TIGR01344
1006551005264	active site
1006551005265	isocitrate lyase; Provisional; Region: PRK15063
1006551005266	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1006551005267	tetramer interface [polypeptide binding]; other site
1006551005268	active site
1006551005269	Mg2+/Mn2+ binding site [ion binding]; other site
1006551005270	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
1006551005271	bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated; Region: aceK; PRK02946
1006551005272	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
1006551005273	transcriptional repressor IclR; Provisional; Region: PRK11569
1006551005274	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1006551005275	Bacterial transcriptional regulator; Region: IclR; pfam01614
1006551005276	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
1006551005277	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
1006551005278	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
1006551005279	substrate binding pocket [chemical binding]; other site
1006551005280	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
1006551005281	B12 binding site [chemical binding]; other site
1006551005282	cobalt ligand [ion binding]; other site
1006551005283	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
1006551005284	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
1006551005285	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1006551005286	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1006551005287	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
1006551005288	active site pocket [active]
1006551005289	oxyanion hole [active]
1006551005290	catalytic triad [active]
1006551005291	active site nucleophile [active]
1006551005292	Post-segregation antitoxin CcdA; Region: CcdA; pfam07362
1006551005293	CcdB protein; Region: CcdB; cl03380
1006551005294	shikimate 5-dehydrogenase; Reviewed; Region: PRK12550
1006551005295	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1006551005296	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1006551005297	shikimate binding site; other site
1006551005298	NAD(P) binding site [chemical binding]; other site
1006551005299	L-sorbose-1-phosphate reductase; Region: sorbose_phosphate_red; cd08238
1006551005300	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1006551005301	putative NAD(P) binding site [chemical binding]; other site
1006551005302	catalytic Zn binding site [ion binding]; other site
1006551005303	PTS system, mannose/fructose/sorbose family, IID component; Region: EIID-AGA; TIGR00828
1006551005304	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
1006551005305	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1006551005306	active site
1006551005307	phosphorylation site [posttranslational modification]
1006551005308	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1006551005309	active pocket/dimerization site; other site
1006551005310	active site
1006551005311	phosphorylation site [posttranslational modification]
1006551005312	sorbitol-6-phosphate 2-dehydrogenase; Provisional; Region: PRK06171
1006551005313	classical (c) SDRs; Region: SDR_c; cd05233
1006551005314	NAD(P) binding site [chemical binding]; other site
1006551005315	active site
1006551005316	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
1006551005317	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1006551005318	putative DNA binding site [nucleotide binding]; other site
1006551005319	putative Zn2+ binding site [ion binding]; other site
1006551005320	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
1006551005321	23S rRNA pseudouridine synthase F; Provisional; Region: PRK10475
1006551005322	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1006551005323	RNA binding surface [nucleotide binding]; other site
1006551005324	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
1006551005325	probable active site [active]
1006551005326	hypothetical protein; Provisional; Region: PRK10515
1006551005327	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
1006551005328	Sodium Bile acid symporter family; Region: SBF; pfam01758
1006551005329	Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: RtcR; COG4650
1006551005330	Regulator of RNA terminal phosphate cyclase; Region: RtcR; pfam06956
1006551005331	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1006551005332	Walker A motif; other site
1006551005333	ATP binding site [chemical binding]; other site
1006551005334	Walker B motif; other site
1006551005335	arginine finger; other site
1006551005336	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
1006551005337	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1006551005338	Predicted nucleotidyltransferase; Region: Nuc-transf; pfam10127
1006551005339	aspartate kinase III; Validated; Region: PRK09084
1006551005340	AAK_AKiii-LysC-EC: Amino Acid Kinase Superfamily (AAK), AKiii-LysC-EC: this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKIII. AKIII is a monofunctional class enzyme (LysC) found in some...; Region: AAK_AKiii-LysC-EC; cd04258
1006551005341	nucleotide binding site [chemical binding]; other site
1006551005342	putative catalytic residues [active]
1006551005343	aspartate binding site [chemical binding]; other site
1006551005344	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_1; cd04932
1006551005345	lysine allosteric regulatory site; other site
1006551005346	dimer interface [polypeptide binding]; other site
1006551005347	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
1006551005348	dimer interface [polypeptide binding]; other site
1006551005349	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
1006551005350	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
1006551005351	active site
1006551005352	dimer interface [polypeptide binding]; other site
1006551005353	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
1006551005354	dimer interface [polypeptide binding]; other site
1006551005355	active site
1006551005356	WcxM-like, Left-handed parallel beta-Helix (LbH) N-terminal domain: This group is composed of Xanthomonas campestris WcxM and proteins with similarity to the WcxM N-terminal domain. WcxM is thought to be bifunctional, catalyzing both the isomerization...; Region: LbH_WxcM_N_like; cd03358
1006551005357	putative trimer interface [polypeptide binding]; other site
1006551005358	putative active site [active]
1006551005359	putative substrate binding site [chemical binding]; other site
1006551005360	putative CoA binding site [chemical binding]; other site
1006551005361	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1006551005362	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1006551005363	Coenzyme A binding pocket [chemical binding]; other site
1006551005364	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1006551005365	homotrimer interaction site [polypeptide binding]; other site
1006551005366	putative active site [active]
1006551005367	Branched-chain amino acid transport protein (AzlD); Region: AzlD; pfam05437
1006551005368	AzlC protein; Region: AzlC; pfam03591
1006551005369	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
1006551005370	phosphate-starvation-inducible protein PsiE; Provisional; Region: PRK02833
1006551005371	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1006551005372	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551005373	dimer interface [polypeptide binding]; other site
1006551005374	conserved gate region; other site
1006551005375	putative PBP binding loops; other site
1006551005376	ABC-ATPase subunit interface; other site
1006551005377	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551005378	dimer interface [polypeptide binding]; other site
1006551005379	conserved gate region; other site
1006551005380	putative PBP binding loops; other site
1006551005381	ABC-ATPase subunit interface; other site
1006551005382	maltose ABC transporter periplasmic protein; Reviewed; Region: malE; PRK09474
1006551005383	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1006551005384	maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000
1006551005385	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1006551005386	Walker A/P-loop; other site
1006551005387	ATP binding site [chemical binding]; other site
1006551005388	Q-loop/lid; other site
1006551005389	ABC transporter signature motif; other site
1006551005390	Walker B; other site
1006551005391	D-loop; other site
1006551005392	H-loop/switch region; other site
1006551005393	TOBE domain; Region: TOBE_2; pfam08402
1006551005394	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
1006551005395	trimer interface; other site
1006551005396	sugar binding site [chemical binding]; other site
1006551005397	maltose regulon periplasmic protein; Provisional; Region: PRK10564
1006551005398	chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655
1006551005399	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
1006551005400	UbiA prenyltransferase family; Region: UbiA; pfam01040
1006551005401	glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703
1006551005402	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
1006551005403	putative acyl-acceptor binding pocket; other site
1006551005404	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
1006551005405	LexA repressor; Validated; Region: PRK00215
1006551005406	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
1006551005407	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1006551005408	Catalytic site [active]
1006551005409	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
1006551005410	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
1006551005411	hypothetical protein; Provisional; Region: PRK10428
1006551005412	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1006551005413	metal binding site 2 [ion binding]; metal-binding site
1006551005414	putative DNA binding helix; other site
1006551005415	metal binding site 1 [ion binding]; metal-binding site
1006551005416	dimer interface [polypeptide binding]; other site
1006551005417	structural Zn2+ binding site [ion binding]; other site
1006551005418	Cupin domain; Region: Cupin_2; cl17218
1006551005419	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
1006551005420	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1006551005421	FMN binding site [chemical binding]; other site
1006551005422	active site
1006551005423	catalytic residues [active]
1006551005424	substrate binding site [chemical binding]; other site
1006551005425	phage shock protein G; Reviewed; Region: pspG; PRK09459
1006551005426	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
1006551005427	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
1006551005428	NADP binding site [chemical binding]; other site
1006551005429	dimer interface [polypeptide binding]; other site
1006551005430	replicative DNA helicase; Provisional; Region: PRK08006
1006551005431	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1006551005432	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1006551005433	Walker A motif; other site
1006551005434	ATP binding site [chemical binding]; other site
1006551005435	Walker B motif; other site
1006551005436	DNA binding loops [nucleotide binding]
1006551005437	alanine racemase; Reviewed; Region: alr; PRK00053
1006551005438	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
1006551005439	active site
1006551005440	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1006551005441	substrate binding site [chemical binding]; other site
1006551005442	catalytic residues [active]
1006551005443	dimer interface [polypeptide binding]; other site
1006551005444	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
1006551005445	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1006551005446	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551005447	homodimer interface [polypeptide binding]; other site
1006551005448	catalytic residue [active]
1006551005449	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1006551005450	active site
1006551005451	motif I; other site
1006551005452	motif II; other site
1006551005453	Uncharacterized conserved protein [Function unknown]; Region: COG0432
1006551005454	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
1006551005455	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1006551005456	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1006551005457	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1006551005458	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1006551005459	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1006551005460	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1006551005461	dimer interface [polypeptide binding]; other site
1006551005462	ssDNA binding site [nucleotide binding]; other site
1006551005463	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1006551005464	putative single-stranded DNA-binding protein; Region: PHA01740
1006551005465	Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein [Cell envelope biogenesis, outer membrane]; Region: COG4623
1006551005466	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551005467	substrate binding pocket [chemical binding]; other site
1006551005468	membrane-bound complex binding site; other site
1006551005469	hinge residues; other site
1006551005470	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1006551005471	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1006551005472	catalytic residue [active]
1006551005473	outer membrane receptor FepA; Provisional; Region: PRK13524
1006551005474	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1006551005475	N-terminal plug; other site
1006551005476	ligand-binding site [chemical binding]; other site
1006551005477	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551005478	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1006551005479	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551005480	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
1006551005481	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1006551005482	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1006551005483	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1006551005484	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1006551005485	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1006551005486	Surface antigen; Region: Bac_surface_Ag; pfam01103
1006551005487	anti-adapter protein IraM; Provisional; Region: PRK09919
1006551005488	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
1006551005489	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1006551005490	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1006551005491	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1006551005492	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551005493	redox-sensitivie transcriptional activator SoxR; Provisional; Region: PRK15002
1006551005494	Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator; Region: HTH_SoxR; cd01110
1006551005495	DNA binding residues [nucleotide binding]
1006551005496	dimer interface [polypeptide binding]; other site
1006551005497	[2Fe-2S] cluster binding site [ion binding]; other site
1006551005498	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1006551005499	GST_N family, Saccharomyces cerevisiae GTT1-like subfamily; composed of predominantly uncharacterized proteins with similarity to the S. cerevisiae GST protein, GTT1, and the Schizosaccharomyces pombe GST-III. GSTs are cytosolic dimeric proteins involved...; Region: GST_N_GTT1_like; cd03046
1006551005500	putative C-terminal domain interface [polypeptide binding]; other site
1006551005501	putative GSH binding site (G-site) [chemical binding]; other site
1006551005502	putative dimer interface [polypeptide binding]; other site
1006551005503	C-terminal, alpha helical domain of GTT1-like Glutathione S-transferases; Region: GST_C_GTT1_like; cd03189
1006551005504	putative N-terminal domain interface [polypeptide binding]; other site
1006551005505	putative dimer interface [polypeptide binding]; other site
1006551005506	putative substrate binding pocket (H-site) [chemical binding]; other site
1006551005507	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1006551005508	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
1006551005509	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
1006551005510	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551005511	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551005512	The C-terminal substrate binding domain of LysR-like transcriptional regulator CidR, contains the type 2 periplasmic binding fold; Region: PBP2_CidR; cd08438
1006551005513	putative dimerization interface [polypeptide binding]; other site
1006551005514	Putative effector of murein hydrolase LrgA [General function prediction only]; Region: COG1380
1006551005515	Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346
1006551005516	Fimbrial protein; Region: Fimbrial; cl01416
1006551005517	fimbrial assembly chaperone SthB; Provisional; Region: PRK15295
1006551005518	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1006551005519	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1006551005520	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1006551005521	PapC N-terminal domain; Region: PapC_N; pfam13954
1006551005522	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1006551005523	PapC C-terminal domain; Region: PapC_C; pfam13953
1006551005524	Fimbrial protein; Region: Fimbrial; cl01416
1006551005525	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1006551005526	Fimbrial protein; Region: Fimbrial; cl01416
1006551005527	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1006551005528	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
1006551005529	Na binding site [ion binding]; other site
1006551005530	Predicted membrane protein [Function unknown]; Region: COG3162
1006551005531	acetyl-CoA synthetase; Provisional; Region: PRK00174
1006551005532	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
1006551005533	active site
1006551005534	CoA binding site [chemical binding]; other site
1006551005535	acyl-activating enzyme (AAE) consensus motif; other site
1006551005536	AMP binding site [chemical binding]; other site
1006551005537	acetate binding site [chemical binding]; other site
1006551005538	glutamate/aspartate:proton symporter; Provisional; Region: gltP; PRK11283
1006551005539	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1006551005540	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1006551005541	potential frameshift: common BLAST hit: gi|238892571|ref|YP_002917305.1| formate dehydrogenase-H
1006551005542	D-allose kinase; Provisional; Region: PRK09698
1006551005543	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1006551005544	nucleotide binding site [chemical binding]; other site
1006551005545	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1006551005546	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1006551005547	substrate binding site [chemical binding]; other site
1006551005548	hexamer interface [polypeptide binding]; other site
1006551005549	metal binding site [ion binding]; metal-binding site
1006551005550	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1006551005551	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1006551005552	TM-ABC transporter signature motif; other site
1006551005553	D-allose transporter ATP-binding protein; Provisional; Region: PRK09700
1006551005554	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551005555	Walker A/P-loop; other site
1006551005556	ATP binding site [chemical binding]; other site
1006551005557	Q-loop/lid; other site
1006551005558	ABC transporter signature motif; other site
1006551005559	Walker B; other site
1006551005560	D-loop; other site
1006551005561	H-loop/switch region; other site
1006551005562	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1006551005563	D-allose transporter subunit; Provisional; Region: PRK09701
1006551005564	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1006551005565	DNA-binding transcriptional repressor RpiR; Provisional; Region: PRK11337
1006551005566	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1006551005567	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1006551005568	putative active site [active]
1006551005569	ribose-5-phosphate isomerase B; Provisional; Region: PRK05571
1006551005570	putative hydrolase; Provisional; Region: PRK02113
1006551005571	carbon-phosphorus lyase complex accessory protein; Provisional; Region: phnP; PRK11244
1006551005572	ribose 1,5-bisphosphokinase; Provisional; Region: PRK10078
1006551005573	active site
1006551005574	phosphonate metabolism protein PhnM; Provisional; Region: PRK15446
1006551005575	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1006551005576	PhnM is believed to be a subunit of the membrane associated C-P lyase complex. C-P lyase is thought to catalyze the direct cleavage of inactivated C-P bonds to yield inorganic phosphate and the corresponding hydrocarbons. It is responsible for cleavage...; Region: PhnM; cd01306
1006551005577	active site
1006551005578	ABC-type phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PhnL; COG4778
1006551005579	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551005580	Walker A/P-loop; other site
1006551005581	ATP binding site [chemical binding]; other site
1006551005582	Q-loop/lid; other site
1006551005583	ABC transporter signature motif; other site
1006551005584	Walker B; other site
1006551005585	D-loop; other site
1006551005586	H-loop/switch region; other site
1006551005587	phosphonate C-P lyase system protein PhnK; Provisional; Region: phnK; PRK11701
1006551005588	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1006551005589	Walker A/P-loop; other site
1006551005590	ATP binding site [chemical binding]; other site
1006551005591	Q-loop/lid; other site
1006551005592	ABC transporter signature motif; other site
1006551005593	Walker B; other site
1006551005594	D-loop; other site
1006551005595	H-loop/switch region; other site
1006551005596	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1006551005597	Phosphonate metabolism protein PhnJ; Region: PhnJ; pfam06007
1006551005598	Bacterial phosphonate metabolism protein (PhnI); Region: PhnI; pfam05861
1006551005599	carbon-phosphorus lyase complex subunit; Validated; Region: phnH; PRK10147
1006551005600	Phosphonate metabolism protein PhnG; Region: PhnG; pfam06754
1006551005601	phosphonate metabolism transcriptional regulator PhnF; Provisional; Region: PRK10079
1006551005602	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551005603	DNA-binding site [nucleotide binding]; DNA binding site
1006551005604	UTRA domain; Region: UTRA; pfam07702
1006551005605	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
1006551005606	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1006551005607	dimer interface [polypeptide binding]; other site
1006551005608	hypothetical protein; Provisional; Region: PRK10220
1006551005609	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
1006551005610	PhnA protein; Region: PhnA; pfam03831
1006551005611	proline/glycine betaine transporter; Provisional; Region: PRK10642
1006551005612	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551005613	putative substrate translocation pore; other site
1006551005614	Osmosensory transporter coiled coil; Region: Osmo_CC; pfam08946
1006551005615	chaperone-modulator protein CbpM; Provisional; Region: PRK10265
1006551005616	MerR HTH family regulatory protein; Region: MerR_2; pfam13591
1006551005617	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
1006551005618	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1006551005619	HSP70 interaction site [polypeptide binding]; other site
1006551005620	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1006551005621	substrate binding site [polypeptide binding]; other site
1006551005622	dimer interface [polypeptide binding]; other site
1006551005623	integral membrane protein, YjbE family; Region: R_switched_YjbE; TIGR03717
1006551005624	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
1006551005625	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
1006551005626	catalytic residues [active]
1006551005627	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1006551005628	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1006551005629	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
1006551005630	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1006551005631	Protein of unknown function (DUF1176); Region: DUF1176; pfam06674
1006551005632	putative transcriptional regulator; Provisional; Region: PRK11640
1006551005633	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
1006551005634	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
1006551005635	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
1006551005636	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
1006551005637	DsbD alpha interface [polypeptide binding]; other site
1006551005638	catalytic residues [active]
1006551005639	divalent-cation tolerance protein CutA; Provisional; Region: PRK10645
1006551005640	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1006551005641	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
1006551005642	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
1006551005643	Aspartase; Region: Aspartase; cd01357
1006551005644	active sites [active]
1006551005645	tetramer interface [polypeptide binding]; other site
1006551005646	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
1006551005647	putative transporter; Provisional; Region: PRK11021
1006551005648	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1006551005649	oligomerisation interface [polypeptide binding]; other site
1006551005650	mobile loop; other site
1006551005651	roof hairpin; other site
1006551005652	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
1006551005653	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1006551005654	ring oligomerisation interface [polypeptide binding]; other site
1006551005655	ATP/Mg binding site [chemical binding]; other site
1006551005656	stacking interactions; other site
1006551005657	hinge regions; other site
1006551005658	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
1006551005659	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
1006551005660	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39C; cd02419
1006551005661	putative active site [active]
1006551005662	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1006551005663	ATP-binding cassette domain of PrtD, subfamily C; Region: ABCC_Protease_Secretion; cd03246
1006551005664	Walker A/P-loop; other site
1006551005665	ATP binding site [chemical binding]; other site
1006551005666	Q-loop/lid; other site
1006551005667	ABC transporter signature motif; other site
1006551005668	Walker B; other site
1006551005669	D-loop; other site
1006551005670	H-loop/switch region; other site
1006551005671	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
1006551005672	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1006551005673	HlyD family secretion protein; Region: HlyD_3; pfam13437
1006551005674	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1006551005675	PapC N-terminal domain; Region: PapC_N; pfam13954
1006551005676	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1006551005677	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1006551005678	PapC C-terminal domain; Region: PapC_C; pfam13953
1006551005679	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1006551005680	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1006551005681	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1006551005682	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
1006551005683	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1006551005684	DNA binding site [nucleotide binding]
1006551005685	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
1006551005686	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1006551005687	FeS/SAM binding site; other site
1006551005688	elongation factor P; Validated; Region: PRK00529
1006551005689	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1006551005690	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1006551005691	RNA binding site [nucleotide binding]; other site
1006551005692	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1006551005693	RNA binding site [nucleotide binding]; other site
1006551005694	Predicted small secreted protein [Function unknown]; Region: COG5510
1006551005695	entericidin B membrane lipoprotein; Provisional; Region: PRK10081
1006551005696	multidrug efflux system protein; Provisional; Region: PRK11431
1006551005697	outer membrane lipoprotein Blc; Provisional; Region: PRK10477
1006551005698	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
1006551005699	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
1006551005700	Iron-sulfur protein interface; other site
1006551005701	proximal quinone binding site [chemical binding]; other site
1006551005702	C-subunit interface; other site
1006551005703	distal quinone binding site; other site
1006551005704	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
1006551005705	D-subunit interface [polypeptide binding]; other site
1006551005706	Iron-sulfur protein interface; other site
1006551005707	proximal quinone binding site [chemical binding]; other site
1006551005708	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
1006551005709	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1006551005710	catalytic loop [active]
1006551005711	iron binding site [ion binding]; other site
1006551005712	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
1006551005713	L-aspartate oxidase; Provisional; Region: PRK06175
1006551005714	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1006551005715	poxB regulator PoxA; Provisional; Region: PRK09350
1006551005716	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1006551005717	motif 1; other site
1006551005718	dimer interface [polypeptide binding]; other site
1006551005719	active site
1006551005720	motif 2; other site
1006551005721	motif 3; other site
1006551005722	inner membrane transporter YjeM; Provisional; Region: PRK15238
1006551005723	putative mechanosensitive channel protein; Provisional; Region: PRK10929
1006551005724	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
1006551005725	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1006551005726	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
1006551005727	GTPase RsgA; Reviewed; Region: PRK12288
1006551005728	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1006551005729	RNA binding site [nucleotide binding]; other site
1006551005730	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
1006551005731	GTPase/Zn-binding domain interface [polypeptide binding]; other site
1006551005732	GTP/Mg2+ binding site [chemical binding]; other site
1006551005733	G4 box; other site
1006551005734	G5 box; other site
1006551005735	G1 box; other site
1006551005736	Switch I region; other site
1006551005737	G2 box; other site
1006551005738	G3 box; other site
1006551005739	Switch II region; other site
1006551005740	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
1006551005741	catalytic site [active]
1006551005742	putative active site [active]
1006551005743	putative substrate binding site [chemical binding]; other site
1006551005744	dimer interface [polypeptide binding]; other site
1006551005745	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551005746	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1006551005747	substrate binding pocket [chemical binding]; other site
1006551005748	membrane-bound complex binding site; other site
1006551005749	hinge residues; other site
1006551005750	epoxyqueuosine reductase; Region: TIGR00276
1006551005751	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
1006551005752	putative carbohydrate kinase; Provisional; Region: PRK10565
1006551005753	Uncharacterized conserved protein [Function unknown]; Region: COG0062
1006551005754	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
1006551005755	putative substrate binding site [chemical binding]; other site
1006551005756	putative ATP binding site [chemical binding]; other site
1006551005757	ADP-binding protein; Provisional; Region: PRK10646
1006551005758	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
1006551005759	AMIN domain; Region: AMIN; pfam11741
1006551005760	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1006551005761	active site
1006551005762	metal binding site [ion binding]; metal-binding site
1006551005763	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
1006551005764	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551005765	ATP binding site [chemical binding]; other site
1006551005766	Mg2+ binding site [ion binding]; other site
1006551005767	G-X-G motif; other site
1006551005768	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
1006551005769	ATP binding site [chemical binding]; other site
1006551005770	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
1006551005771	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
1006551005772	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1006551005773	bacterial Hfq-like; Region: Hfq; cd01716
1006551005774	hexamer interface [polypeptide binding]; other site
1006551005775	Sm1 motif; other site
1006551005776	RNA binding site [nucleotide binding]; other site
1006551005777	Sm2 motif; other site
1006551005778	GTPase HflX; Provisional; Region: PRK11058
1006551005779	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
1006551005780	HflX GTPase family; Region: HflX; cd01878
1006551005781	G1 box; other site
1006551005782	GTP/Mg2+ binding site [chemical binding]; other site
1006551005783	Switch I region; other site
1006551005784	G2 box; other site
1006551005785	G3 box; other site
1006551005786	Switch II region; other site
1006551005787	G4 box; other site
1006551005788	G5 box; other site
1006551005789	FtsH protease regulator HflK; Provisional; Region: PRK10930
1006551005790	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
1006551005791	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
1006551005792	FtsH protease regulator HflC; Provisional; Region: PRK11029
1006551005793	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
1006551005794	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3242
1006551005795	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
1006551005796	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
1006551005797	GDP-binding site [chemical binding]; other site
1006551005798	ACT binding site; other site
1006551005799	IMP binding site; other site
1006551005800	Predicted transcriptional regulator [Transcription]; Region: COG1959
1006551005801	transcriptional repressor NsrR; Provisional; Region: PRK11014
1006551005802	exoribonuclease R; Provisional; Region: PRK11642
1006551005803	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1006551005804	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1006551005805	RNB domain; Region: RNB; pfam00773
1006551005806	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
1006551005807	RNA binding site [nucleotide binding]; other site
1006551005808	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
1006551005809	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
1006551005810	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1006551005811	Uncharacterized protein family (UPF0128); Region: UPF0128; cl00799
1006551005812	isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561
1006551005813	Proteins involved in DNA damage response, similar to the AidB gene product; Region: AidB; cd01154
1006551005814	FAD binding site [chemical binding]; other site
1006551005815	substrate binding site [chemical binding]; other site
1006551005816	catalytic residues [active]
1006551005817	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1006551005818	putative biofilm stress and motility protein A; Provisional; Region: PRK14864
1006551005819	esterase; Provisional; Region: PRK10566
1006551005820	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1006551005821	transcriptional repressor UlaR; Provisional; Region: PRK13509
1006551005822	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1006551005823	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1006551005824	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
1006551005825	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1006551005826	PTS system ascorbate-specific transporter subunits IICB; Provisional; Region: PRK09548
1006551005827	Uncharacterized protein conserved in bacteria [Function unknown]; Region: SgaT; COG3037
1006551005828	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1006551005829	active site
1006551005830	P-loop; other site
1006551005831	phosphorylation site [posttranslational modification]
1006551005832	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1006551005833	active site
1006551005834	phosphorylation site [posttranslational modification]
1006551005835	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
1006551005836	active site
1006551005837	dimer interface [polypeptide binding]; other site
1006551005838	magnesium binding site [ion binding]; other site
1006551005839	L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13209
1006551005840	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1006551005841	AP (apurinic/apyrimidinic) site pocket; other site
1006551005842	DNA interaction; other site
1006551005843	Metal-binding active site; metal-binding site
1006551005844	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1006551005845	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1006551005846	intersubunit interface [polypeptide binding]; other site
1006551005847	active site
1006551005848	Zn2+ binding site [ion binding]; other site
1006551005849	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551005850	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1006551005851	putative substrate translocation pore; other site
1006551005852	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1006551005853	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1006551005854	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1006551005855	dimer interface [polypeptide binding]; other site
1006551005856	ssDNA binding site [nucleotide binding]; other site
1006551005857	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1006551005858	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1006551005859	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1006551005860	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1006551005861	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1006551005862	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1006551005863	EamA-like transporter family; Region: EamA; pfam00892
1006551005864	EamA-like transporter family; Region: EamA; pfam00892
1006551005865	Cell envelope opacity-associated protein A [Cell envelope biogenesis, outer membrane]; Region: OapA; COG3061
1006551005866	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
1006551005867	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
1006551005868	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1006551005869	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1006551005870	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
1006551005871	iron-sulfur cluster repair di-iron protein; Provisional; Region: PRK10992
1006551005872	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
1006551005873	Hemerythrin-like domain; Region: Hr-like; cd12108
1006551005874	Fe binding site [ion binding]; other site
1006551005875	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1006551005876	EamA-like transporter family; Region: EamA; pfam00892
1006551005877	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1006551005878	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1006551005879	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551005880	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551005881	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1006551005882	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
1006551005883	NADP binding site [chemical binding]; other site
1006551005884	Predicted transcriptional regulators [Transcription]; Region: COG1733
1006551005885	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1006551005886	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
1006551005887	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
1006551005888	active site
1006551005889	metal binding site [ion binding]; metal-binding site
1006551005890	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1006551005891	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
1006551005892	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1006551005893	active site
1006551005894	Predicted transcriptional regulator [General function prediction only]; Region: COG3054
1006551005895	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
1006551005896	DNA-binding transcriptional regulator AraC; Provisional; Region: PRK10572
1006551005897	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1006551005898	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551005899	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551005900	Beta-galactosidase [Carbohydrate transport and metabolism]; Region: LacA; COG1874
1006551005901	Beta-galactosidase; Region: Glyco_hydro_42; pfam02449
1006551005902	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
1006551005903	galactoside permease; Reviewed; Region: lacY; PRK09528
1006551005904	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1006551005905	Domain of unknown function DUF21; Region: DUF21; pfam01595
1006551005906	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1006551005907	Transporter associated domain; Region: CorC_HlyC; smart01091
1006551005908	methionine sulfoxide reductase A; Provisional; Region: PRK00058
1006551005909	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
1006551005910	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1006551005911	Surface antigen; Region: Bac_surface_Ag; pfam01103
1006551005912	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
1006551005913	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1006551005914	Family of unknown function (DUF490); Region: DUF490; pfam04357
1006551005915	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
1006551005916	putative active site pocket [active]
1006551005917	dimerization interface [polypeptide binding]; other site
1006551005918	putative catalytic residue [active]
1006551005919	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
1006551005920	dimer interface [polypeptide binding]; other site
1006551005921	substrate binding site [chemical binding]; other site
1006551005922	metal binding sites [ion binding]; metal-binding site
1006551005923	Periplasmic binding domain of ABC-type YtfQ-like transport systems; Region: PBP1_YtfQ_like; cd06309
1006551005924	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1006551005925	putative ligand binding site [chemical binding]; other site
1006551005926	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1006551005927	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1006551005928	Walker A/P-loop; other site
1006551005929	ATP binding site [chemical binding]; other site
1006551005930	Q-loop/lid; other site
1006551005931	ABC transporter signature motif; other site
1006551005932	Walker B; other site
1006551005933	D-loop; other site
1006551005934	H-loop/switch region; other site
1006551005935	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1006551005936	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1006551005937	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1006551005938	TM-ABC transporter signature motif; other site
1006551005939	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1006551005940	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1006551005941	TM-ABC transporter signature motif; other site
1006551005942	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
1006551005943	AMP binding site [chemical binding]; other site
1006551005944	metal binding site [ion binding]; metal-binding site
1006551005945	active site
1006551005946	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
1006551005947	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1006551005948	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1006551005949	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1006551005950	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1006551005951	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1006551005952	Coenzyme A binding pocket [chemical binding]; other site
1006551005953	Aldose 1-epimerase, similar to Escherichia coli c4013; Region: Aldose_epim_Ec_c4013; cd09023
1006551005954	active site
1006551005955	catalytic residues [active]
1006551005956	NADPH-dependent butanol dehydrogenase involved in the butanol and ethanol formation pathway in bacteria; Region: NADPH_BDH; cd08179
1006551005957	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
1006551005958	putative active site [active]
1006551005959	metal binding site [ion binding]; metal-binding site
1006551005960	Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2; Region: ALDH_F6_MMSDH; cd07085
1006551005961	methylmalonic acid semialdehyde dehydrogenase; Region: MMSDH; TIGR01722
1006551005962	tetrameric interface [polypeptide binding]; other site
1006551005963	NAD binding site [chemical binding]; other site
1006551005964	catalytic residues [active]
1006551005965	hypothetical protein; Provisional; Region: PRK05255
1006551005966	peptidase PmbA; Provisional; Region: PRK11040
1006551005967	Cytochrome b562; Region: Cytochrom_B562; cl01546
1006551005968	PRD domain protein EF_0829/AHA_3910; Region: EF_0829; TIGR03582
1006551005969	Glycine-rich SFCGS; Region: Gly_rich_SFCGS; cl11916
1006551005970	conserved hypothetical protein EF_0831/AHA_3912; Region: EF_0831; TIGR03578
1006551005971	conserved hypothetical protein EF_0832/AHA_3913; Region: EF_0832; TIGR03580
1006551005972	conserved hypothetical protein EF_0833/AHA_3914; Region: EF_0833; TIGR03579
1006551005973	dihydroorotase; Provisional; Region: PRK09237
1006551005974	Metallo-dependent hydrolases, subgroup B is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_B; cd01307
1006551005975	active site
1006551005976	uncharacterized pyridoxal phosphate-dependent enzyme; Region: selA_rel; TIGR01437
1006551005977	Protein of unknown function (DUF1341); Region: DUF1341; pfam07071
1006551005978	Lactonase, 7-bladed beta-propeller; Region: Lactonase; pfam10282
1006551005979	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1006551005980	HTH domain; Region: HTH_11; pfam08279
1006551005981	Mga helix-turn-helix domain; Region: Mga; pfam05043
1006551005982	PRD domain; Region: PRD; pfam00874
1006551005983	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1006551005984	active site
1006551005985	P-loop; other site
1006551005986	phosphorylation site [posttranslational modification]
1006551005987	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1006551005988	active site
1006551005989	phosphorylation site [posttranslational modification]
1006551005990	Domain of unknown function (DUF4280); Region: DUF4280; pfam14107
1006551005991	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
1006551005992	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1006551005993	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1006551005994	Gp5 C-terminal repeat (3 copies); Region: Gp5_C; pfam06715
1006551005995	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
1006551005996	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1006551005997	FeS/SAM binding site; other site
1006551005998	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
1006551005999	ATP cone domain; Region: ATP-cone; pfam03477
1006551006000	Class III ribonucleotide reductase; Region: RNR_III; cd01675
1006551006001	effector binding site; other site
1006551006002	active site
1006551006003	Zn binding site [ion binding]; other site
1006551006004	glycine loop; other site
1006551006005	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1006551006006	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1006551006007	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1006551006008	putative active site [active]
1006551006009	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1006551006010	active site
1006551006011	P-loop; other site
1006551006012	phosphorylation site [posttranslational modification]
1006551006013	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
1006551006014	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
1006551006015	NAD binding site [chemical binding]; other site
1006551006016	sugar binding site [chemical binding]; other site
1006551006017	divalent metal binding site [ion binding]; other site
1006551006018	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1006551006019	dimer interface [polypeptide binding]; other site
1006551006020	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1006551006021	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; cl17295
1006551006022	trehalose-6-phosphate hydrolase; Provisional; Region: PRK10933
1006551006023	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1006551006024	Ca binding site [ion binding]; other site
1006551006025	active site
1006551006026	catalytic site [active]
1006551006027	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
1006551006028	PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional; Region: PRK11007
1006551006029	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1006551006030	active site turn [active]
1006551006031	phosphorylation site [posttranslational modification]
1006551006032	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1006551006033	trehalose repressor; Provisional; Region: treR; PRK09492
1006551006034	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1006551006035	DNA binding site [nucleotide binding]
1006551006036	domain linker motif; other site
1006551006037	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
1006551006038	dimerization interface [polypeptide binding]; other site
1006551006039	ligand binding site [chemical binding]; other site
1006551006040	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
1006551006041	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
1006551006042	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1006551006043	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1006551006044	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1006551006045	motif II; other site
1006551006046	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1006551006047	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1006551006048	homotrimer interaction site [polypeptide binding]; other site
1006551006049	putative active site [active]
1006551006050	N-acetylglucosamine-binding protein A; Reviewed; Region: PRK13211
1006551006051	Chitin binding domain; Region: Chitin_bind_3; pfam03067
1006551006052	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
1006551006053	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
1006551006054	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
1006551006055	Aspartate carbamoyltransferase, catalytic chain [Nucleotide transport and metabolism]; Region: PyrB; COG0540
1006551006056	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1006551006057	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1006551006058	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1006551006059	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
1006551006060	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1006551006061	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1006551006062	RNase E inhibitor protein; Provisional; Region: PRK11191
1006551006063	MiaE tRNA-modifying nonheme diiron monooxygenase, ferritin-like diiron-binding domain; Region: MiaE; cd07910
1006551006064	active site
1006551006065	dinuclear metal binding site [ion binding]; other site
1006551006066	dimerization interface [polypeptide binding]; other site
1006551006067	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1006551006068	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1006551006069	substrate binding pocket [chemical binding]; other site
1006551006070	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1006551006071	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1006551006072	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1006551006073	Coenzyme A binding pocket [chemical binding]; other site
1006551006074	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
1006551006075	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1006551006076	HIGH motif; other site
1006551006077	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1006551006078	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1006551006079	active site
1006551006080	KMSKS motif; other site
1006551006081	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1006551006082	tRNA binding surface [nucleotide binding]; other site
1006551006083	anticodon binding site; other site
1006551006084	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
1006551006085	DNA polymerase III subunit chi; Validated; Region: PRK05728
1006551006086	multifunctional aminopeptidase A; Provisional; Region: PRK00913
1006551006087	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1006551006088	interface (dimer of trimers) [polypeptide binding]; other site
1006551006089	Substrate-binding/catalytic site; other site
1006551006090	Zn-binding sites [ion binding]; other site
1006551006091	lipopolysaccharide ABC transporter permease LptF; Provisional; Region: PRK15120
1006551006092	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1006551006093	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
1006551006094	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1006551006095	Bacterial protein of unknown function (DUF853); Region: DUF853; pfam05872
1006551006096	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1006551006097	Walker A motif; other site
1006551006098	ATP binding site [chemical binding]; other site
1006551006099	Predicted sugar epimerase [Carbohydrate transport and metabolism]; Region: COG4130
1006551006100	Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2; Region: ALDH_F6_MMSDH; cd07085
1006551006101	methylmalonic acid semialdehyde dehydrogenase; Region: MMSDH; TIGR01722
1006551006102	tetrameric interface [polypeptide binding]; other site
1006551006103	NAD binding site [chemical binding]; other site
1006551006104	catalytic residues [active]
1006551006105	Uncharacterized enzyme involved in inositol metabolism [Carbohydrate transport and metabolism]; Region: IolB; COG3718
1006551006106	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1006551006107	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1006551006108	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1006551006109	putative active site [active]
1006551006110	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1006551006111	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1006551006112	substrate binding site [chemical binding]; other site
1006551006113	ATP binding site [chemical binding]; other site
1006551006114	Uncharacterized protein conserved in bacteria (DUF2090); Region: DUF2090; pfam09863
1006551006115	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3892
1006551006116	Acetolactate synthase [Amino acid transport and metabolism]; Region: COG3962
1006551006117	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1006551006118	PYR/PP interface [polypeptide binding]; other site
1006551006119	dimer interface [polypeptide binding]; other site
1006551006120	TPP binding site [chemical binding]; other site
1006551006121	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1006551006122	Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins similar to Rhizobium leguminosarum bv. viciae IolD. IolD plays an important role in myo-inositol catabolism; Region: TPP_IolD; cd02003
1006551006123	TPP-binding site; other site
1006551006124	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1006551006125	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1006551006126	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1006551006127	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
1006551006128	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
1006551006129	Metal-binding active site; metal-binding site
1006551006130	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1006551006131	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
1006551006132	Metal-binding active site; metal-binding site
1006551006133	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
1006551006134	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551006135	putative substrate translocation pore; other site
1006551006136	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551006137	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1006551006138	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
1006551006139	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
1006551006140	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1006551006141	Walker A/P-loop; other site
1006551006142	ATP binding site [chemical binding]; other site
1006551006143	Q-loop/lid; other site
1006551006144	ABC transporter signature motif; other site
1006551006145	Walker B; other site
1006551006146	D-loop; other site
1006551006147	H-loop/switch region; other site
1006551006148	TOBE domain; Region: TOBE_2; pfam08402
1006551006149	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
1006551006150	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1006551006151	active site
1006551006152	metal binding site [ion binding]; metal-binding site
1006551006153	hexamer interface [polypeptide binding]; other site
1006551006154	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1006551006155	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551006156	dimer interface [polypeptide binding]; other site
1006551006157	conserved gate region; other site
1006551006158	putative PBP binding loops; other site
1006551006159	ABC-ATPase subunit interface; other site
1006551006160	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551006161	dimer interface [polypeptide binding]; other site
1006551006162	conserved gate region; other site
1006551006163	putative PBP binding loops; other site
1006551006164	ABC-ATPase subunit interface; other site
1006551006165	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1006551006166	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
1006551006167	putative NAD(P) binding site [chemical binding]; other site
1006551006168	putative substrate binding site [chemical binding]; other site
1006551006169	catalytic Zn binding site [ion binding]; other site
1006551006170	structural Zn binding site [ion binding]; other site
1006551006171	dimer interface [polypeptide binding]; other site
1006551006172	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1006551006173	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551006174	S-adenosylmethionine binding site [chemical binding]; other site
1006551006175	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1006551006176	active site
1006551006177	Integrase core domain; Region: rve; pfam00665
1006551006178	Integrase core domain; Region: rve_3; pfam13683
1006551006179	Transposase; Region: HTH_Tnp_1; cl17663
1006551006180	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
1006551006181	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551006182	S-adenosylmethionine binding site [chemical binding]; other site
1006551006183	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1006551006184	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1006551006185	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1006551006186	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1006551006187	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1006551006188	sequence-specific DNA binding site [nucleotide binding]; other site
1006551006189	salt bridge; other site
1006551006190	integrase; Provisional; Region: PRK09692
1006551006191	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1006551006192	active site
1006551006193	Int/Topo IB signature motif; other site
1006551006194	TIGR02646 family protein; Region: TIGR02646
1006551006195	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551006196	AAA domain; Region: AAA_21; pfam13304
1006551006197	Walker A/P-loop; other site
1006551006198	ATP binding site [chemical binding]; other site
1006551006199	AAA domain; Region: AAA_21; pfam13304
1006551006200	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551006201	ATP binding site [chemical binding]; other site
1006551006202	Walker A/P-loop; other site
1006551006203	Q-loop/lid; other site
1006551006204	ABC transporter signature motif; other site
1006551006205	Walker B; other site
1006551006206	D-loop; other site
1006551006207	H-loop/switch region; other site
1006551006208	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1006551006209	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1006551006210	HsdM N-terminal domain; Region: HsdM_N; pfam12161
1006551006211	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
1006551006212	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551006213	S-adenosylmethionine binding site [chemical binding]; other site
1006551006214	5'-nucleotidase; Region: 5-nucleotidase; pfam06189
1006551006215	EcoKI restriction-modification system protein HsdS; Provisional; Region: PRK09737
1006551006216	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1006551006217	HsdM N-terminal domain; Region: HsdM_N; pfam12161
1006551006218	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
1006551006219	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1006551006220	Domain of unknown function (DUF4145); Region: DUF4145; pfam13643
1006551006221	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: HsdR; COG4096
1006551006222	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1006551006223	ATP binding site [chemical binding]; other site
1006551006224	putative Mg++ binding site [ion binding]; other site
1006551006225	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351
1006551006226	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
1006551006227	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; cl17523
1006551006228	Predicted GTPase [General function prediction only]; Region: COG3596
1006551006229	YfjP GTPase; Region: YfjP; cd11383
1006551006230	G1 box; other site
1006551006231	GTP/Mg2+ binding site [chemical binding]; other site
1006551006232	Switch I region; other site
1006551006233	G2 box; other site
1006551006234	Switch II region; other site
1006551006235	G3 box; other site
1006551006236	G4 box; other site
1006551006237	G5 box; other site
1006551006238	Antirestriction protein; Region: Antirestrict; pfam03230
1006551006239	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1006551006240	MPN+ (JAMM) motif; other site
1006551006241	Zinc-binding site [ion binding]; other site
1006551006242	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
1006551006243	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
1006551006244	Methyltransferase domain; Region: Methyltransf_27; pfam13708
1006551006245	Protein of unknown function (DUF4238); Region: DUF4238; pfam14022
1006551006246	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_19; cd07262
1006551006247	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1006551006248	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; cl07446
1006551006249	DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases.  They exists as monomers and homodimers; Region: NUC; cd00091
1006551006250	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
1006551006251	active site
1006551006252	substrate binding site [chemical binding]; other site
1006551006253	Mg2+ binding site [ion binding]; other site
1006551006254	Protein of unknown function (DUF1176); Region: DUF1176; pfam06674
1006551006255	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1006551006256	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1006551006257	DNA binding site [nucleotide binding]
1006551006258	domain linker motif; other site
1006551006259	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
1006551006260	dimerization interface [polypeptide binding]; other site
1006551006261	ligand binding site [chemical binding]; other site
1006551006262	Domain of unknown function (DUF336); Region: DUF336; pfam03928
1006551006263	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1006551006264	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
1006551006265	inhibitor site; inhibition site
1006551006266	active site
1006551006267	dimer interface [polypeptide binding]; other site
1006551006268	catalytic residue [active]
1006551006269	flagellin modification protein A; Provisional; Region: PRK09186
1006551006270	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1006551006271	NAD(P) binding site [chemical binding]; other site
1006551006272	active site
1006551006273	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
1006551006274	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
1006551006275	active site pocket [active]
1006551006276	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551006277	putative substrate translocation pore; other site
1006551006278	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551006279	L-fucose isomerase (FucIase) and L-arabinose isomerase (AI) family; composed of FucIase, AI and similar proteins. FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose...; Region: L-fuc_L-ara-isomerases; cl00947
1006551006280	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1006551006281	substrate binding site [chemical binding]; other site
1006551006282	trimer interface [polypeptide binding]; other site
1006551006283	Mn binding site [ion binding]; other site
1006551006284	metabolite-proton symporter; Region: 2A0106; TIGR00883
1006551006285	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551006286	putative substrate translocation pore; other site
1006551006287	outer membrane porin, OprD family; Region: OprD; pfam03573
1006551006288	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1006551006289	catalytic core [active]
1006551006290	Survival protein SurE; Region: SurE; pfam01975
1006551006291	Uncharacterized conserved protein [Function unknown]; Region: COG2850
1006551006292	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
1006551006293	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1006551006294	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1006551006295	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
1006551006296	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1006551006297	Walker A/P-loop; other site
1006551006298	ATP binding site [chemical binding]; other site
1006551006299	Q-loop/lid; other site
1006551006300	ABC transporter signature motif; other site
1006551006301	Walker B; other site
1006551006302	D-loop; other site
1006551006303	H-loop/switch region; other site
1006551006304	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1006551006305	Walker A/P-loop; other site
1006551006306	ATP binding site [chemical binding]; other site
1006551006307	Q-loop/lid; other site
1006551006308	ABC transporter signature motif; other site
1006551006309	Walker B; other site
1006551006310	D-loop; other site
1006551006311	H-loop/switch region; other site
1006551006312	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1006551006313	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
1006551006314	HlyD family secretion protein; Region: HlyD; pfam00529
1006551006315	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1006551006316	HlyD family secretion protein; Region: HlyD_3; pfam13437
1006551006317	superfamily containing globins and truncated hemoglobins; Region: globin_like; cl00280
1006551006318	heme-binding site [chemical binding]; other site
1006551006319	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1006551006320	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1006551006321	metal binding site [ion binding]; metal-binding site
1006551006322	active site
1006551006323	I-site; other site
1006551006324	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1006551006325	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1006551006326	active site
1006551006327	HIGH motif; other site
1006551006328	dimer interface [polypeptide binding]; other site
1006551006329	KMSKS motif; other site
1006551006330	tryptophan permease; Provisional; Region: PRK10483
1006551006331	aromatic amino acid transport protein; Region: araaP; TIGR00837
1006551006332	tryptophanase/L-cysteine desulfhydrase, PLP-dependent; Provisional; Region: tnaA; PRK13238
1006551006333	Tryptophanase family (Tnase). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to tryptophanase (Tnase) and tyrosine phenol-lyase (TPL). Tnase and TPL are...; Region: Tnase_like; cd00617
1006551006334	substrate binding site [chemical binding]; other site
1006551006335	tetramer interface [polypeptide binding]; other site
1006551006336	catalytic residue [active]
1006551006337	tryptophanase leader peptide; Region: tnaC_leader; TIGR02616
1006551006338	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
1006551006339	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
1006551006340	propanediol utilization phosphotransacylase; Provisional; Region: PRK15070
1006551006341	Propanediol utilisation protein PduL; Region: PduL; pfam06130
1006551006342	Propanediol utilisation protein PduL; Region: PduL; pfam06130
1006551006343	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1006551006344	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
1006551006345	Hexamer interface [polypeptide binding]; other site
1006551006346	Hexagonal pore residue; other site
1006551006347	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
1006551006348	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1006551006349	Pyruvate formate lyase; Region: PFL; pfam02901
1006551006350	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
1006551006351	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
1006551006352	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
1006551006353	dimer interface [polypeptide binding]; other site
1006551006354	active site
1006551006355	glycine loop; other site
1006551006356	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
1006551006357	1,3-propanediol dehydrogenase (PPD) catalyzes the reduction of 3-hydroxypropionaldehyde (3-HPA) to 1,3-propanediol in glycerol metabolism; Region: PDD; cd08180
1006551006358	putative active site [active]
1006551006359	metal binding site [ion binding]; metal-binding site
1006551006360	Ethanolamine utilisation protein EutN/carboxysome; Region: EutN_CcmL; pfam03319
1006551006361	Hexamer/Pentamer interface [polypeptide binding]; other site
1006551006362	central pore; other site
1006551006363	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
1006551006364	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
1006551006365	putative catalytic cysteine [active]
1006551006366	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1006551006367	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
1006551006368	Hexamer interface [polypeptide binding]; other site
1006551006369	Hexagonal pore residue; other site
1006551006370	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1006551006371	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
1006551006372	Hexamer interface [polypeptide binding]; other site
1006551006373	Hexagonal pore residue; other site
1006551006374	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1006551006375	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
1006551006376	Hexamer interface [polypeptide binding]; other site
1006551006377	Hexagonal pore residue; other site
1006551006378	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
1006551006379	DNA binding site [nucleotide binding]
1006551006380	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1006551006381	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1006551006382	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
1006551006383	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1006551006384	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551006385	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551006386	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator similar to DntR, which is involved in the catabolism of dinitrotoluene; contains the type 2 periplasmic binding fold; Region: PBP2_DntR_like_3; cd08461
1006551006387	putative substrate binding pocket [chemical binding]; other site
1006551006388	putative dimerization interface [polypeptide binding]; other site
1006551006389	fosfomycin resistance protein FosB; Provisional; Region: PRK04101
1006551006390	FosA, a Fosfomycin resistance protein, catalyzes the addition of glutathione to the antibiotic fosfomycin, making it inactive; Region: FosA; cd07244
1006551006391	dimer interface [polypeptide binding]; other site
1006551006392	Mn binding site [ion binding]; other site
1006551006393	K binding site [ion binding]; other site
1006551006394	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2929
1006551006395	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3514
1006551006396	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1006551006397	Predicted acetamidase/formamidase [Energy production and conversion]; Region: COG2421
1006551006398	endoribonuclease SymE; Provisional; Region: PRK13605
1006551006399	EcoKI restriction-modification system protein HsdS; Provisional; Region: PRK09737
1006551006400	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1006551006401	HsdM N-terminal domain; Region: HsdM_N; pfam12161
1006551006402	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
1006551006403	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1006551006404	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: HsdR; COG4096
1006551006405	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; cl14958
1006551006406	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1006551006407	ATP binding site [chemical binding]; other site
1006551006408	putative Mg++ binding site [ion binding]; other site
1006551006409	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1006551006410	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551006411	DNA-binding site [nucleotide binding]; DNA binding site
1006551006412	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1006551006413	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551006414	homodimer interface [polypeptide binding]; other site
1006551006415	catalytic residue [active]
1006551006416	transcriptional regulator SlyA; Provisional; Region: PRK03573
1006551006417	MarR family; Region: MarR; pfam01047
1006551006418	efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998
1006551006419	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1006551006420	Protein of unknown function (DUF2955); Region: DUF2955; pfam11168
1006551006421	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551006422	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551006423	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_5; cd08426
1006551006424	putative dimerization interface [polypeptide binding]; other site
1006551006425	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314
1006551006426	Nucleoside recognition; Region: Gate; pfam07670
1006551006427	hypothetical protein; Provisional; Region: PRK10519
1006551006428	M20 Peptidase Aminoacylase 1 amhX_like subfamily; Region: M20_Acy1_amhX_like; cd08018
1006551006429	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1006551006430	metal binding site [ion binding]; metal-binding site
1006551006431	putative dimer interface [polypeptide binding]; other site
1006551006432	Protein of unknown function (DUF3343); Region: DUF3343; pfam11823
1006551006433	Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism]; Region: COG1924
1006551006434	CoA-substrate-specific enzyme activase, putative; Region: CoA_E_activ; TIGR00241
1006551006435	Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB [Amino acid transport and metabolism]; Region: HgdB; COG1775
1006551006436	benzoyl-CoA reductase, subunit C; Region: benz_CoA_red_C; TIGR02263
1006551006437	Uncharacterized conserved protein (DUF2164); Region: DUF2164; cl02278
1006551006438	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
1006551006439	Ligand Binding Site [chemical binding]; other site
1006551006440	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
1006551006441	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
1006551006442	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
1006551006443	ParB-like nuclease domain; Region: ParBc; pfam02195
1006551006444	multidrug efflux system protein MdtM; Provisional; Region: PRK15403
1006551006445	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551006446	putative substrate translocation pore; other site
1006551006447	Protein of unknown function (DUF445); Region: DUF445; pfam04286
1006551006448	LysE type translocator; Region: LysE; cl00565
1006551006449	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1006551006450	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1006551006451	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551006452	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1006551006453	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
1006551006454	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
1006551006455	NAD(P) binding site [chemical binding]; other site
1006551006456	catalytic residues [active]
1006551006457	YfaZ precursor; Region: YfaZ; pfam07437
1006551006458	putative GTP-binding protein YjiA; Provisional; Region: PRK11537
1006551006459	The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112
1006551006460	P-loop, Walker A motif; other site
1006551006461	Base recognition motif; other site
1006551006462	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
1006551006463	Uncharacterized small protein [Function unknown]; Region: COG2879
1006551006464	carbon starvation protein A; Provisional; Region: PRK15015
1006551006465	Carbon starvation protein CstA; Region: CstA; pfam02554
1006551006466	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1006551006467	Flavin Reductases; Region: FlaRed; cl00801
1006551006468	4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Region: HpaB-2; TIGR02310
1006551006469	4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241
1006551006470	4-hydroxyphenylacetate catabolism regulatory protein HpaA; Region: HpaA; TIGR02297
1006551006471	Cupin domain; Region: Cupin_2; pfam07883
1006551006472	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551006473	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551006474	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
1006551006475	putative substrate translocation pore; other site
1006551006476	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
1006551006477	2-oxo-hepta-3-ene-1,7-dioic acid hydratase; Region: HpaH; TIGR02312
1006551006478	5-carboxymethyl-2-hydroxymuconate isomerase (CHMI) is a trimeric enzyme catalyzing the isomerization of the unsaturated ketone 5-(carboxymethyl)-2-hydroxymuconate to 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dionate. This is one step in the...; Region: CHMI; cd00580
1006551006479	putative substrate binding pocket [chemical binding]; other site
1006551006480	trimer interface [polypeptide binding]; other site
1006551006481	The Class III extradiol dioxygenase, homoprotocatechuate 2,3-dioxygenase, catalyzes the key ring cleavage step in the metabolism of homoprotocatechuate; Region: HPCD; cd07370
1006551006482	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
1006551006483	putative active site [active]
1006551006484	putative metal binding site [ion binding]; other site
1006551006485	5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; Region: HpaE; TIGR02299
1006551006486	Human aldehyde dehydrogenase family 8 member A1-like; Region: ALDH_F8_HMSADH; cd07093
1006551006487	NAD binding site [chemical binding]; other site
1006551006488	catalytic residues [active]
1006551006489	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1006551006490	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421
1006551006491	homoprotocatechuate degradation operon regulator, HpaR; Region: HpaR; TIGR02337
1006551006492	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1006551006493	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Bacterial Cryptic D-Serine Dehydratase; Region: PLPDE_III_cryptic_DSD; cd06818
1006551006494	dimer interface [polypeptide binding]; other site
1006551006495	Predicted amino acid aldolase or racemase [Amino acid transport and metabolism]; Region: COG3616
1006551006496	active site
1006551006497	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1006551006498	substrate binding site [chemical binding]; other site
1006551006499	catalytic residue [active]
1006551006500	D-aminoacylases (N-acyl-D-Amino acid amidohydrolases) catalyze the hydrolysis of N-acyl-D-amino acids to produce the corresponding D-amino acids, which are used as intermediates in the synthesis of pesticides, bioactive peptides, and antibiotics; Region: D-aminoacylase; cd01297
1006551006501	N-acyl-D-aspartate/D-glutamate deacylase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3653
1006551006502	active site
1006551006503	putative substrate binding pocket [chemical binding]; other site
1006551006504	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1006551006505	homotrimer interaction site [polypeptide binding]; other site
1006551006506	putative active site [active]
1006551006507	Solute carrier 5 family, sodium/glucose transporters and related proteins; solute-binding domain; Region: SLC5sbd; cd10322
1006551006508	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1006551006509	Na binding site [ion binding]; other site
1006551006510	2-keto-3-deoxy-galactonokinase [Carbohydrate transport and metabolism]; Region: DgoK; COG3734
1006551006511	2-keto-3-deoxy-galactonokinase; Region: DGOK; pfam05035
1006551006512	2-dehydro-3-deoxy-6-phosphogalactonate aldolase; Reviewed; Region: PRK09140
1006551006513	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1006551006514	active site
1006551006515	intersubunit interface [polypeptide binding]; other site
1006551006516	catalytic residue [active]
1006551006517	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1006551006518	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1006551006519	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1006551006520	putative active site [active]
1006551006521	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1006551006522	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1006551006523	Coenzyme A binding pocket [chemical binding]; other site
1006551006524	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1006551006525	Coenzyme A binding pocket [chemical binding]; other site
1006551006526	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
1006551006527	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551006528	D-galactonate transporter; Region: 2A0114; TIGR00893
1006551006529	putative substrate translocation pore; other site
1006551006530	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1006551006531	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551006532	DNA-binding site [nucleotide binding]; DNA binding site
1006551006533	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1006551006534	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1006551006535	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
1006551006536	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1006551006537	putative NAD(P) binding site [chemical binding]; other site
1006551006538	catalytic Zn binding site [ion binding]; other site
1006551006539	structural Zn binding site [ion binding]; other site
1006551006540	altronate oxidoreductase; Provisional; Region: PRK03643
1006551006541	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1006551006542	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1006551006543	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
1006551006544	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1006551006545	Walker A motif; other site
1006551006546	ATP binding site [chemical binding]; other site
1006551006547	Walker B motif; other site
1006551006548	arginine finger; other site
1006551006549	Transcriptional antiterminator [Transcription]; Region: COG3933
1006551006550	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
1006551006551	active pocket/dimerization site; other site
1006551006552	active site
1006551006553	phosphorylation site [posttranslational modification]
1006551006554	PRD domain; Region: PRD; pfam00874
1006551006555	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1006551006556	active pocket/dimerization site; other site
1006551006557	active site
1006551006558	phosphorylation site [posttranslational modification]
1006551006559	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1006551006560	active site
1006551006561	phosphorylation site [posttranslational modification]
1006551006562	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
1006551006563	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
1006551006564	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
1006551006565	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1006551006566	dimer interface [polypeptide binding]; other site
1006551006567	active site
1006551006568	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1006551006569	dimer interface [polypeptide binding]; other site
1006551006570	active site
1006551006571	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
1006551006572	A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS_1; cd05710
1006551006573	putative active site [active]
1006551006574	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
1006551006575	hypothetical protein; Provisional; Region: PRK09956
1006551006576	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1006551006577	Essential protein Yae1, N terminal; Region: Yae1_N; pfam09811
1006551006578	phosphoglycerol transferase I; Provisional; Region: PRK03776
1006551006579	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
1006551006580	hypothetical protein; Provisional; Region: PRK11667
1006551006581	DNA replication protein DnaC; Validated; Region: PRK07952
1006551006582	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1006551006583	Walker A motif; other site
1006551006584	ATP binding site [chemical binding]; other site
1006551006585	Walker B motif; other site
1006551006586	primosomal protein DnaI; Provisional; Region: PRK02854
1006551006587	hypothetical protein; Provisional; Region: PRK09917
1006551006588	Uncharacterized conserved protein [Function unknown]; Region: COG2966
1006551006589	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
1006551006590	4-hydroxybenzoate 3-monooxygenase; Validated; Region: PRK08243
1006551006591	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1006551006592	4-hydroxyphenylacetate catabolism regulatory protein HpaA; Region: HpaA; TIGR02297
1006551006593	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551006594	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1006551006595	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1006551006596	DNA binding residues [nucleotide binding]
1006551006597	dimerization interface [polypeptide binding]; other site
1006551006598	DNA-binding transcriptional activator BglJ; Provisional; Region: PRK11475
1006551006599	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1006551006600	DNA binding residues [nucleotide binding]
1006551006601	dimerization interface [polypeptide binding]; other site
1006551006602	This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens  ProX Ala-tRNA(Pro)...; Region: ProX_deacylase; cd04333
1006551006603	putative deacylase active site [active]
1006551006604	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1006551006605	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1006551006606	ferric iron reductase involved in ferric hydroximate transport; Provisional; Region: PRK10647
1006551006607	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
1006551006608	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
1006551006609	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1006551006610	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1006551006611	metal binding site [ion binding]; metal-binding site
1006551006612	active site
1006551006613	I-site; other site
1006551006614	Protein of unknown function (DUF1435); Region: DUF1435; pfam07256
1006551006615	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
1006551006616	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
1006551006617	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551006618	S-adenosylmethionine binding site [chemical binding]; other site
1006551006619	DNA polymerase III subunit psi; Validated; Region: PRK06856
1006551006620	ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491
1006551006621	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1006551006622	Coenzyme A binding pocket [chemical binding]; other site
1006551006623	dUMP phosphatase; Provisional; Region: PRK09449
1006551006624	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1006551006625	motif II; other site
1006551006626	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
1006551006627	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
1006551006628	G1 box; other site
1006551006629	putative GEF interaction site [polypeptide binding]; other site
1006551006630	GTP/Mg2+ binding site [chemical binding]; other site
1006551006631	Switch I region; other site
1006551006632	G2 box; other site
1006551006633	G3 box; other site
1006551006634	Switch II region; other site
1006551006635	G4 box; other site
1006551006636	G5 box; other site
1006551006637	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
1006551006638	periplasmic protein; Provisional; Region: PRK10568
1006551006639	BON domain; Region: BON; pfam04972
1006551006640	BON domain; Region: BON; pfam04972
1006551006641	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
1006551006642	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
1006551006643	active site
1006551006644	nucleophile elbow; other site
1006551006645	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1006551006646	active site
1006551006647	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1006551006648	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1006551006649	Nucleoside recognition; Region: Gate; pfam07670
1006551006650	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1006551006651	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
1006551006652	intersubunit interface [polypeptide binding]; other site
1006551006653	active site
1006551006654	catalytic residue [active]
1006551006655	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
1006551006656	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1006551006657	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1006551006658	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; smart00941
1006551006659	phosphopentomutase; Provisional; Region: PRK05362
1006551006660	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
1006551006661	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
1006551006662	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
1006551006663	lipoate-protein ligase A; Provisional; Region: lplA; PRK03822
1006551006664	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
1006551006665	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
1006551006666	hypothetical protein; Provisional; Region: PRK11246
1006551006667	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
1006551006668	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1006551006669	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1006551006670	motif II; other site
1006551006671	DNA repair protein RadA; Region: sms; TIGR00416
1006551006672	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
1006551006673	Walker A motif/ATP binding site; other site
1006551006674	ATP binding site [chemical binding]; other site
1006551006675	Walker B motif; other site
1006551006676	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1006551006677	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1006551006678	non-specific DNA binding site [nucleotide binding]; other site
1006551006679	salt bridge; other site
1006551006680	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
1006551006681	sequence-specific DNA binding site [nucleotide binding]; other site
1006551006682	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional NadR-like proteins; Region: NMNAT_NadR; cd02167
1006551006683	active site
1006551006684	(T/H)XGH motif; other site
1006551006685	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
1006551006686	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
1006551006687	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1006551006688	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1006551006689	ABC transporter; Region: ABC_tran_2; pfam12848
1006551006690	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1006551006691	lytic murein transglycosylase; Provisional; Region: PRK11619
1006551006692	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1006551006693	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1006551006694	catalytic residue [active]
1006551006695	Trp operon repressor; Provisional; Region: PRK01381
1006551006696	inosine/xanthosine triphosphatase; Reviewed; Region: PRK05074
1006551006697	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1006551006698	catalytic core [active]
1006551006699	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
1006551006700	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551006701	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
1006551006702	hypothetical protein; Provisional; Region: PRK10756
1006551006703	CreA protein; Region: CreA; pfam05981
1006551006704	DNA-binding response regulator CreB; Provisional; Region: PRK11083
1006551006705	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551006706	active site
1006551006707	phosphorylation site [posttranslational modification]
1006551006708	intermolecular recognition site; other site
1006551006709	dimerization interface [polypeptide binding]; other site
1006551006710	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1006551006711	DNA binding site [nucleotide binding]
1006551006712	sensory histidine kinase CreC; Provisional; Region: PRK11100
1006551006713	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1006551006714	dimerization interface [polypeptide binding]; other site
1006551006715	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1006551006716	dimer interface [polypeptide binding]; other site
1006551006717	phosphorylation site [posttranslational modification]
1006551006718	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551006719	ATP binding site [chemical binding]; other site
1006551006720	Mg2+ binding site [ion binding]; other site
1006551006721	G-X-G motif; other site
1006551006722	Inner membrane protein CreD; Region: CreD; cl01844
1006551006723	two-component response regulator; Provisional; Region: PRK11173
1006551006724	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551006725	active site
1006551006726	phosphorylation site [posttranslational modification]
1006551006727	intermolecular recognition site; other site
1006551006728	dimerization interface [polypeptide binding]; other site
1006551006729	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1006551006730	DNA binding site [nucleotide binding]
1006551006731	rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: LasT; COG0565
1006551006732	putative RNA methyltransferase; Provisional; Region: PRK10433
1006551006733	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
1006551006734	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
1006551006735	putative catalytic residues [active]
1006551006736	putative nucleotide binding site [chemical binding]; other site
1006551006737	putative aspartate binding site [chemical binding]; other site
1006551006738	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
1006551006739	dimer interface [polypeptide binding]; other site
1006551006740	putative threonine allosteric regulatory site; other site
1006551006741	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
1006551006742	putative threonine allosteric regulatory site; other site
1006551006743	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1006551006744	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1006551006745	homoserine kinase; Provisional; Region: PRK01212
1006551006746	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1006551006747	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1006551006748	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
1006551006749	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
1006551006750	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551006751	catalytic residue [active]
1006551006752	hypothetical protein; Validated; Region: PRK02101
1006551006753	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1006551006754	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
1006551006755	transaldolase-like protein; Provisional; Region: PTZ00411
1006551006756	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
1006551006757	active site
1006551006758	dimer interface [polypeptide binding]; other site
1006551006759	catalytic residue [active]
1006551006760	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1006551006761	MPT binding site; other site
1006551006762	trimer interface [polypeptide binding]; other site
1006551006763	metabolite-proton symporter; Region: 2A0106; TIGR00883
1006551006764	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551006765	putative substrate translocation pore; other site
1006551006766	hypothetical protein; Provisional; Region: PRK10659
1006551006767	hypothetical protein; Provisional; Region: PRK10236
1006551006768	Domain of unknown function (DUF3944); Region: DUF3944; pfam13099
1006551006769	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735
1006551006770	hypothetical protein; Provisional; Region: PRK10154
1006551006771	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1006551006772	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1006551006773	nucleotide binding site [chemical binding]; other site
1006551006774	chaperone protein DnaJ; Provisional; Region: PRK10767
1006551006775	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1006551006776	HSP70 interaction site [polypeptide binding]; other site
1006551006777	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
1006551006778	substrate binding site [polypeptide binding]; other site
1006551006779	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1006551006780	Zn binding sites [ion binding]; other site
1006551006781	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1006551006782	dimer interface [polypeptide binding]; other site
1006551006783	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551006784	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551006785	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1006551006786	dimerization interface [polypeptide binding]; other site
1006551006787	Lysozyme family protein [General function prediction only]; Region: zliS; COG3926
1006551006788	Glycosyl hydrolase 108; Region: Glyco_hydro_108; pfam05838
1006551006789	Predicted Peptidoglycan domain; Region: PG_binding_3; pfam09374
1006551006790	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
1006551006791	Chitinase [Carbohydrate transport and metabolism]; Region: ChiA; COG3325
1006551006792	The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an...; Region: GH18_chitinase; cd06548
1006551006793	active site
1006551006794	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
1006551006795	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
1006551006796	aromatic chitin/cellulose binding site residues [chemical binding]; other site
1006551006797	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
1006551006798	Helix-turn-helix domain; Region: HTH_36; pfam13730
1006551006799	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
1006551006800	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
1006551006801	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551006802	The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429
1006551006803	putative dimerization interface [polypeptide binding]; other site
1006551006804	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1006551006805	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
1006551006806	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
1006551006807	active site
1006551006808	Riboflavin kinase; Region: Flavokinase; smart00904
1006551006809	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
1006551006810	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1006551006811	HIGH motif; other site
1006551006812	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1006551006813	active site
1006551006814	KMSKS motif; other site
1006551006815	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
1006551006816	tRNA binding surface [nucleotide binding]; other site
1006551006817	anticodon binding site; other site
1006551006818	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1006551006819	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
1006551006820	lipoprotein signal peptidase; Provisional; Region: PRK14787
1006551006821	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
1006551006822	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1006551006823	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
1006551006824	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
1006551006825	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
1006551006826	active site
1006551006827	tetramer interface [polypeptide binding]; other site
1006551006828	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551006829	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551006830	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
1006551006831	putative dimerization interface [polypeptide binding]; other site
1006551006832	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2828
1006551006833	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1006551006834	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1006551006835	transmembrane helices; other site
1006551006836	Citrate transporter; Region: CitMHS; pfam03600
1006551006837	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1006551006838	transmembrane helices; other site
1006551006839	putative hydratase; Provisional; Region: PRK11413
1006551006840	Aconitase catalytic domain; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: Aconitase; cl00285
1006551006841	substrate binding site [chemical binding]; other site
1006551006842	ligand binding site [chemical binding]; other site
1006551006843	Aconitase swivel domain. Aconitase (aconitate hydratase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes swivelling conformational change in the enzyme...; Region: Aconitase_swivel; cl00215
1006551006844	substrate binding site [chemical binding]; other site
1006551006845	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551006846	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551006847	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1006551006848	putative effector binding pocket; other site
1006551006849	dimerization interface [polypeptide binding]; other site
1006551006850	alanine-tRNA ligase; Region: PLN02961
1006551006851	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; cl08469
1006551006852	Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms]; Region: CitB; COG4565
1006551006853	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551006854	active site
1006551006855	phosphorylation site [posttranslational modification]
1006551006856	intermolecular recognition site; other site
1006551006857	dimerization interface [polypeptide binding]; other site
1006551006858	Transcriptional regulator; Region: CitT; pfam12431
1006551006859	Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290
1006551006860	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1006551006861	putative active site [active]
1006551006862	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551006863	ATP binding site [chemical binding]; other site
1006551006864	Mg2+ binding site [ion binding]; other site
1006551006865	G-X-G motif; other site
1006551006866	oxaloacetate decarboxylase subunit beta; Provisional; Region: PRK15476
1006551006867	oxaloacetate decarboxylase; Provisional; Region: PRK14040
1006551006868	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
1006551006869	active site
1006551006870	catalytic residues [active]
1006551006871	metal binding site [ion binding]; metal-binding site
1006551006872	homodimer binding site [polypeptide binding]; other site
1006551006873	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1006551006874	carboxyltransferase (CT) interaction site; other site
1006551006875	biotinylation site [posttranslational modification]; other site
1006551006876	oxaloacetate decarboxylase subunit gamma; Provisional; Region: PRK02919
1006551006877	Na+/citrate symporter [Energy production and conversion]; Region: CitS; COG3493
1006551006878	[citrate (pro-3S)-lyase] ligase; Region: cit_ly_ligase; TIGR00124
1006551006879	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
1006551006880	putative active site [active]
1006551006881	(T/H)XGH motif; other site
1006551006882	citrate lyase subunit gamma; Provisional; Region: PRK13253
1006551006883	citrate lyase, beta subunit; Region: citE; TIGR01588
1006551006884	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
1006551006885	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
1006551006886	triphosphoribosyl-dephospho-CoA synthase CitG; Region: citrate_citG; TIGR03125
1006551006887	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
1006551006888	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1006551006889	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1006551006890	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
1006551006891	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
1006551006892	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
1006551006893	catalytic site [active]
1006551006894	subunit interface [polypeptide binding]; other site
1006551006895	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
1006551006896	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1006551006897	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1006551006898	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
1006551006899	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1006551006900	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1006551006901	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
1006551006902	IMP binding site; other site
1006551006903	dimer interface [polypeptide binding]; other site
1006551006904	interdomain contacts; other site
1006551006905	partial ornithine binding site; other site
1006551006906	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1006551006907	glutathione-regulated potassium-efflux system ancillary protein KefF; Provisional; Region: PRK00871
1006551006908	glutathione-regulated potassium-efflux system protein KefC; Provisional; Region: PRK03562
1006551006909	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
1006551006910	TrkA-N domain; Region: TrkA_N; pfam02254
1006551006911	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1006551006912	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
1006551006913	folate binding site [chemical binding]; other site
1006551006914	NADP+ binding site [chemical binding]; other site
1006551006915	bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Region: apaH; TIGR00668
1006551006916	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
1006551006917	active site
1006551006918	metal binding site [ion binding]; metal-binding site
1006551006919	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
1006551006920	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1006551006921	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
1006551006922	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
1006551006923	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
1006551006924	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
1006551006925	SurA N-terminal domain; Region: SurA_N; pfam09312
1006551006926	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1006551006927	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1006551006928	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
1006551006929	OstA-like protein; Region: OstA; pfam03968
1006551006930	Organic solvent tolerance protein; Region: OstA_C; pfam04453
1006551006931	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
1006551006932	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
1006551006933	putative metal binding site [ion binding]; other site
1006551006934	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1006551006935	HSP70 interaction site [polypeptide binding]; other site
1006551006936	Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms]; Region: CitB; COG4565
1006551006937	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551006938	active site
1006551006939	phosphorylation site [posttranslational modification]
1006551006940	intermolecular recognition site; other site
1006551006941	dimerization interface [polypeptide binding]; other site
1006551006942	Transcriptional regulator; Region: CitT; pfam12431
1006551006943	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
1006551006944	Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290
1006551006945	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1006551006946	putative active site [active]
1006551006947	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551006948	ATP binding site [chemical binding]; other site
1006551006949	Mg2+ binding site [ion binding]; other site
1006551006950	G-X-G motif; other site
1006551006951	2-hydroxycarboxylate transporter family; Region: 2HCT; pfam03390
1006551006952	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase; Region: CitX; pfam03802
1006551006953	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1006551006954	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1006551006955	active site
1006551006956	ATP-dependent helicase HepA; Validated; Region: PRK04914
1006551006957	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1006551006958	ATP binding site [chemical binding]; other site
1006551006959	putative Mg++ binding site [ion binding]; other site
1006551006960	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1006551006961	nucleotide binding region [chemical binding]; other site
1006551006962	ATP-binding site [chemical binding]; other site
1006551006963	DNA polymerase II; Reviewed; Region: PRK05762
1006551006964	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase II and similar bacterial family-B DNA polymerases; Region: DNA_polB_II_exo; cd05784
1006551006965	active site
1006551006966	catalytic site [active]
1006551006967	substrate binding site [chemical binding]; other site
1006551006968	DNA polymerase type-II subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as...; Region: POLBc_Pol_II; cd05537
1006551006969	active site
1006551006970	metal-binding site
1006551006971	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1006551006972	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1006551006973	intersubunit interface [polypeptide binding]; other site
1006551006974	active site
1006551006975	Zn2+ binding site [ion binding]; other site
1006551006976	L-arabinose isomerase; Provisional; Region: PRK02929
1006551006977	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
1006551006978	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
1006551006979	trimer interface [polypeptide binding]; other site
1006551006980	putative substrate binding site [chemical binding]; other site
1006551006981	putative metal binding site [ion binding]; other site
1006551006982	ribulokinase; Provisional; Region: PRK04123
1006551006983	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
1006551006984	N- and C-terminal domain interface [polypeptide binding]; other site
1006551006985	active site
1006551006986	MgATP binding site [chemical binding]; other site
1006551006987	catalytic site [active]
1006551006988	metal binding site [ion binding]; metal-binding site
1006551006989	carbohydrate binding site [chemical binding]; other site
1006551006990	homodimer interface [polypeptide binding]; other site
1006551006991	DNA-binding transcriptional regulator AraC; Provisional; Region: PRK10572
1006551006992	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1006551006993	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551006994	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551006995	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1006551006996	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1006551006997	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
1006551006998	ATP-binding cassette domain of the thiamine transport system; Region: ABC_ThiQ_thiamine_transporter; cd03298
1006551006999	Walker A/P-loop; other site
1006551007000	ATP binding site [chemical binding]; other site
1006551007001	Q-loop/lid; other site
1006551007002	ABC transporter signature motif; other site
1006551007003	Walker B; other site
1006551007004	D-loop; other site
1006551007005	H-loop/switch region; other site
1006551007006	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
1006551007007	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551007008	dimer interface [polypeptide binding]; other site
1006551007009	conserved gate region; other site
1006551007010	putative PBP binding loops; other site
1006551007011	ABC-ATPase subunit interface; other site
1006551007012	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551007013	dimer interface [polypeptide binding]; other site
1006551007014	conserved gate region; other site
1006551007015	putative PBP binding loops; other site
1006551007016	ABC-ATPase subunit interface; other site
1006551007017	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
1006551007018	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
1006551007019	transcriptional regulator SgrR; Provisional; Region: PRK13626
1006551007020	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1006551007021	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
1006551007022	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551007023	sugar efflux transporter; Region: 2A0120; TIGR00899
1006551007024	putative substrate translocation pore; other site
1006551007025	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551007026	D-galactonate transporter; Region: 2A0114; TIGR00893
1006551007027	putative substrate translocation pore; other site
1006551007028	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551007029	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551007030	The substrate binding domain of LysR-type transcriptional regulator GltC, which activates gltA expression of glutamate synthase operon, contains type 2 periplasmic binding fold; Region: PBP2_GltC_like; cd08434
1006551007031	putative dimerization interface [polypeptide binding]; other site
1006551007032	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
1006551007033	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
1006551007034	active site
1006551007035	catalytic residue [active]
1006551007036	dimer interface [polypeptide binding]; other site
1006551007037	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551007038	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1006551007039	putative substrate translocation pore; other site
1006551007040	shikimate 5-dehydrogenase; Provisional; Region: PRK12548
1006551007041	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1006551007042	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1006551007043	shikimate binding site; other site
1006551007044	NAD(P) binding site [chemical binding]; other site
1006551007045	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1006551007046	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN_family; cd02803
1006551007047	active site
1006551007048	FMN binding site [chemical binding]; other site
1006551007049	substrate binding site [chemical binding]; other site
1006551007050	putative catalytic residue [active]
1006551007051	putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834
1006551007052	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992
1006551007053	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
1006551007054	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
1006551007055	substrate binding site [chemical binding]; other site
1006551007056	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
1006551007057	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
1006551007058	substrate binding site [chemical binding]; other site
1006551007059	ligand binding site [chemical binding]; other site
1006551007060	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
1006551007061	tartrate dehydrogenase; Region: TTC; TIGR02089
1006551007062	2-isopropylmalate synthase; Validated; Region: PRK00915
1006551007063	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
1006551007064	active site
1006551007065	catalytic residues [active]
1006551007066	metal binding site [ion binding]; metal-binding site
1006551007067	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
1006551007068	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
1006551007069	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551007070	The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466
1006551007071	putative substrate binding pocket [chemical binding]; other site
1006551007072	putative dimerization interface [polypeptide binding]; other site
1006551007073	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979
1006551007074	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1006551007075	PYR/PP interface [polypeptide binding]; other site
1006551007076	dimer interface [polypeptide binding]; other site
1006551007077	TPP binding site [chemical binding]; other site
1006551007078	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1006551007079	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1006551007080	TPP-binding site [chemical binding]; other site
1006551007081	dimer interface [polypeptide binding]; other site
1006551007082	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
1006551007083	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1006551007084	putative valine binding site [chemical binding]; other site
1006551007085	dimer interface [polypeptide binding]; other site
1006551007086	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
1006551007087	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
1006551007088	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1006551007089	DNA binding site [nucleotide binding]
1006551007090	domain linker motif; other site
1006551007091	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
1006551007092	dimerization interface [polypeptide binding]; other site
1006551007093	ligand binding site [chemical binding]; other site
1006551007094	mraZ protein; Region: TIGR00242
1006551007095	MraZ protein; Region: MraZ; pfam02381
1006551007096	MraZ protein; Region: MraZ; pfam02381
1006551007097	16S rRNA (cytosine(1402)-N(4))-methyltransferase; Region: TIGR00006
1006551007098	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
1006551007099	cell division protein FtsL; Provisional; Region: PRK10772
1006551007100	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
1006551007101	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1006551007102	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1006551007103	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1006551007104	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1006551007105	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1006551007106	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1006551007107	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
1006551007108	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1006551007109	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1006551007110	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1006551007111	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
1006551007112	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1006551007113	Mg++ binding site [ion binding]; other site
1006551007114	putative catalytic motif [active]
1006551007115	putative substrate binding site [chemical binding]; other site
1006551007116	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
1006551007117	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1006551007118	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1006551007119	cell division protein FtsW; Provisional; Region: PRK10774
1006551007120	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
1006551007121	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1006551007122	active site
1006551007123	homodimer interface [polypeptide binding]; other site
1006551007124	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
1006551007125	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1006551007126	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1006551007127	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1006551007128	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
1006551007129	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1006551007130	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
1006551007131	cell division protein FtsQ; Provisional; Region: PRK10775
1006551007132	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
1006551007133	Cell division protein FtsQ; Region: FtsQ; pfam03799
1006551007134	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
1006551007135	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1006551007136	Cell division protein FtsA; Region: FtsA; pfam14450
1006551007137	cell division protein FtsZ; Validated; Region: PRK09330
1006551007138	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1006551007139	nucleotide binding site [chemical binding]; other site
1006551007140	SulA interaction site; other site
1006551007141	cell division protein FtsZ, alphaProteobacterial C-terminal extension; Region: FtsZ_alphas_C; TIGR03483
1006551007142	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
1006551007143	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
1006551007144	SecA regulator SecM; Provisional; Region: PRK02943
1006551007145	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
1006551007146	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1006551007147	SEC-C motif; Region: SEC-C; pfam02810
1006551007148	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
1006551007149	active site
1006551007150	8-oxo-dGMP binding site [chemical binding]; other site
1006551007151	nudix motif; other site
1006551007152	metal binding site [ion binding]; metal-binding site
1006551007153	DNA gyrase inhibitor; Reviewed; Region: PRK00418
1006551007154	hypothetical protein; Provisional; Region: PRK05287
1006551007155	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
1006551007156	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1006551007157	CoA-binding site [chemical binding]; other site
1006551007158	ATP-binding [chemical binding]; other site
1006551007159	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
1006551007160	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1006551007161	active site
1006551007162	type IV pilin biogenesis protein; Provisional; Region: PRK10573
1006551007163	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1006551007164	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1006551007165	hypothetical protein; Provisional; Region: PRK10436
1006551007166	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
1006551007167	Walker A motif; other site
1006551007168	ATP binding site [chemical binding]; other site
1006551007169	Walker B motif; other site
1006551007170	putative major pilin subunit; Provisional; Region: PRK10574
1006551007171	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830
1006551007172	Pilin (bacterial filament); Region: Pilin; pfam00114
1006551007173	quinolinate phosphoribosyltransferase; Validated; Region: PRK09016
1006551007174	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
1006551007175	dimerization interface [polypeptide binding]; other site
1006551007176	active site
1006551007177	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1006551007178	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1006551007179	amidase catalytic site [active]
1006551007180	Zn binding residues [ion binding]; other site
1006551007181	substrate binding site [chemical binding]; other site
1006551007182	regulatory protein AmpE; Provisional; Region: PRK10987
1006551007183	Glycosyl hydrolase family 43; Region: GH43_1; cd08980
1006551007184	active site
1006551007185	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1006551007186	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551007187	putative substrate translocation pore; other site
1006551007188	aromatic amino acid transporter; Provisional; Region: PRK10238
1006551007189	transcriptional regulator PdhR; Reviewed; Region: pdhR; PRK09464
1006551007190	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551007191	DNA-binding site [nucleotide binding]; DNA binding site
1006551007192	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1006551007193	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
1006551007194	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
1006551007195	dimer interface [polypeptide binding]; other site
1006551007196	TPP-binding site [chemical binding]; other site
1006551007197	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
1006551007198	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1006551007199	E3 interaction surface; other site
1006551007200	lipoyl attachment site [posttranslational modification]; other site
1006551007201	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1006551007202	E3 interaction surface; other site
1006551007203	lipoyl attachment site [posttranslational modification]; other site
1006551007204	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1006551007205	E3 interaction surface; other site
1006551007206	lipoyl attachment site [posttranslational modification]; other site
1006551007207	e3 binding domain; Region: E3_binding; pfam02817
1006551007208	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1006551007209	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
1006551007210	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1006551007211	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1006551007212	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1006551007213	Protein of unknown function (DUF2950); Region: DUF2950; pfam11453
1006551007214	Protein of unknown function (DUF3300); Region: DUF3300; pfam11737
1006551007215	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
1006551007216	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
1006551007217	substrate binding site [chemical binding]; other site
1006551007218	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
1006551007219	substrate binding site [chemical binding]; other site
1006551007220	ligand binding site [chemical binding]; other site
1006551007221	hypothetical protein; Provisional; Region: PRK05248
1006551007222	2-keto-3-deoxygluconate permease; Provisional; Region: PRK12460
1006551007223	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
1006551007224	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
1006551007225	4-hydroxythreonine-4-phosphate dehydrogenase 2; Provisional; Region: pdxA; PRK03371
1006551007226	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1006551007227	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1006551007228	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1006551007229	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
1006551007230	spermidine synthase; Provisional; Region: PRK00811
1006551007231	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551007232	S-adenosylmethionine binding site [chemical binding]; other site
1006551007233	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1006551007234	FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545
1006551007235	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1006551007236	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
1006551007237	multicopper oxidase; Provisional; Region: PRK10965
1006551007238	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1006551007239	Multicopper oxidase; Region: Cu-oxidase; pfam00394
1006551007240	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
1006551007241	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
1006551007242	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
1006551007243	Trp docking motif [polypeptide binding]; other site
1006551007244	putative active site [active]
1006551007245	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1006551007246	active site
1006551007247	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
1006551007248	active site clefts [active]
1006551007249	zinc binding site [ion binding]; other site
1006551007250	dimer interface [polypeptide binding]; other site
1006551007251	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1006551007252	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1006551007253	Walker A/P-loop; other site
1006551007254	ATP binding site [chemical binding]; other site
1006551007255	Q-loop/lid; other site
1006551007256	ABC transporter signature motif; other site
1006551007257	Walker B; other site
1006551007258	D-loop; other site
1006551007259	H-loop/switch region; other site
1006551007260	inner membrane transport permease; Provisional; Region: PRK15066
1006551007261	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1006551007262	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1006551007263	active pocket/dimerization site; other site
1006551007264	active site
1006551007265	phosphorylation site [posttranslational modification]
1006551007266	Putative catalytic polysaccharide deacetylase domain of uncharacterized protein yadE and similar proteins; Region: CE4_yadE_5s; cd10966
1006551007267	putative active site [active]
1006551007268	putative metal binding site [ion binding]; other site
1006551007269	Fimbrial protein; Region: Fimbrial; cl01416
1006551007270	Fimbrial protein; Region: Fimbrial; cl01416
1006551007271	putative fimbrial protein StaE; Provisional; Region: PRK15263
1006551007272	Fimbrial protein; Region: Fimbrial; cl01416
1006551007273	putative fimbrial outer membrane usher protein; Provisional; Region: PRK09828
1006551007274	PapC N-terminal domain; Region: PapC_N; pfam13954
1006551007275	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1006551007276	PapC C-terminal domain; Region: PapC_C; pfam13953
1006551007277	putative chaperone protein EcpD; Provisional; Region: PRK09926
1006551007278	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1006551007279	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1006551007280	Fimbrial protein; Region: Fimbrial; cl01416
1006551007281	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
1006551007282	tetramerization interface [polypeptide binding]; other site
1006551007283	active site
1006551007284	pantoate--beta-alanine ligase; Region: panC; TIGR00018
1006551007285	Pantoate-beta-alanine ligase; Region: PanC; cd00560
1006551007286	active site
1006551007287	ATP-binding site [chemical binding]; other site
1006551007288	pantoate-binding site; other site
1006551007289	HXXH motif; other site
1006551007290	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
1006551007291	oligomerization interface [polypeptide binding]; other site
1006551007292	active site
1006551007293	metal binding site [ion binding]; metal-binding site
1006551007294	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
1006551007295	catalytic center binding site [active]
1006551007296	ATP binding site [chemical binding]; other site
1006551007297	poly(A) polymerase; Region: pcnB; TIGR01942
1006551007298	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1006551007299	active site
1006551007300	NTP binding site [chemical binding]; other site
1006551007301	metal binding triad [ion binding]; metal-binding site
1006551007302	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1006551007303	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
1006551007304	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
1006551007305	Glutamyl- and glutaminyl-tRNA synthetases [Translation, ribosomal structure and biogenesis]; Region: GlnS; COG0008
1006551007306	active site
1006551007307	HIGH motif; other site
1006551007308	nucleotide binding site [chemical binding]; other site
1006551007309	KMSKS motif; other site
1006551007310	RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778
1006551007311	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
1006551007312	2'-5' RNA ligase; Provisional; Region: PRK15124
1006551007313	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
1006551007314	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
1006551007315	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
1006551007316	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1006551007317	ATP binding site [chemical binding]; other site
1006551007318	putative Mg++ binding site [ion binding]; other site
1006551007319	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1006551007320	nucleotide binding region [chemical binding]; other site
1006551007321	ATP-binding site [chemical binding]; other site
1006551007322	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
1006551007323	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
1006551007324	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
1006551007325	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
1006551007326	Type II secretion system (T2SS), protein N; Region: T2SN; pfam01203
1006551007327	Type II secretion system (T2SS), protein M; Region: T2SM; pfam04612
1006551007328	type II secretion system protein L; Region: typeII_sec_gspL; TIGR01709
1006551007329	Type II secretion system (T2SS), protein L; Region: T2SL; pfam05134
1006551007330	GspL periplasmic domain; Region: GspL_C; pfam12693
1006551007331	Type II secretion system (T2SS), protein K; Region: T2SK; pfam03934
1006551007332	Type II secretion system (T2SS), protein J; Region: T2SJ; pfam11612
1006551007333	type II secretion system protein I; Region: gspI; TIGR01707
1006551007334	Type II secretion system (T2SS), protein I; Region: T2SI; pfam02501
1006551007335	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
1006551007336	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
1006551007337	type II secretion system protein G; Region: typeII_sec_gspG; TIGR01710
1006551007338	Type II secretion system (T2SS), protein G; Region: T2SG; pfam08334
1006551007339	type II secretion system protein F; Region: GspF; TIGR02120
1006551007340	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1006551007341	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1006551007342	type II secretion system protein E; Region: type_II_gspE; TIGR02533
1006551007343	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
1006551007344	Walker A motif; other site
1006551007345	ATP binding site [chemical binding]; other site
1006551007346	Walker B motif; other site
1006551007347	type II secretion system protein D; Region: type_II_gspD; TIGR02517
1006551007348	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1006551007349	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1006551007350	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1006551007351	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1006551007352	type II secretion system protein C; Region: typeII_sec_gspC; TIGR01713
1006551007353	Type IV pilus biogenesis; Region: Pilus_PilP; pfam11356
1006551007354	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1006551007355	Family 41 Carbohydrate-Binding Module from pullulanase-like enzymes; Region: CBM41_pullulanase; cd10315
1006551007356	carbohydrate binding site [chemical binding]; other site
1006551007357	alpha-1,6-glucosidases, pullulanase-type; Region: pullul_strch; TIGR02103
1006551007358	Early set domain associated with the catalytic domain of pullulanase (also called dextrinase and alpha-dextrin endo-1,6-alpha glucosidase); Region: E_set_Pullulanase; cd02860
1006551007359	Alpha amylase catalytic domain found in Pullulanase (also called dextrinase; alpha-dextrin endo-1,6-alpha glucosidase), limit dextrinase, and related proteins; Region: AmyAc_Pullulanase_LD-like; cd11341
1006551007360	Ca binding site [ion binding]; other site
1006551007361	active site
1006551007362	catalytic site [active]
1006551007363	Domain of unknown function (DUF3372); Region: DUF3372; pfam11852
1006551007364	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
1006551007365	bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506
1006551007366	Transglycosylase; Region: Transgly; pfam00912
1006551007367	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1006551007368	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
1006551007369	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1006551007370	N-terminal plug; other site
1006551007371	ligand-binding site [chemical binding]; other site
1006551007372	iron-hydroxamate transporter ATP-binding subunit; Provisional; Region: PRK10575
1006551007373	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1006551007374	Walker A/P-loop; other site
1006551007375	ATP binding site [chemical binding]; other site
1006551007376	Q-loop/lid; other site
1006551007377	ABC transporter signature motif; other site
1006551007378	Walker B; other site
1006551007379	D-loop; other site
1006551007380	H-loop/switch region; other site
1006551007381	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
1006551007382	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1006551007383	siderophore binding site; other site
1006551007384	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1006551007385	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1006551007386	ABC-ATPase subunit  interface; other site
1006551007387	dimer interface [polypeptide binding]; other site
1006551007388	putative PBP binding regions; other site
1006551007389	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1006551007390	ABC-ATPase subunit  interface; other site
1006551007391	dimer interface [polypeptide binding]; other site
1006551007392	putative PBP binding regions; other site
1006551007393	hypothetical protein; Provisional; Region: PRK09956
1006551007394	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1006551007395	PDDEXK-like domain of unknown function (DUF3799); Region: DUF3799; pfam12684
1006551007396	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
1006551007397	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1006551007398	inhibitor-cofactor binding pocket; inhibition site
1006551007399	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551007400	catalytic residue [active]
1006551007401	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1006551007402	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
1006551007403	Cl- selectivity filter; other site
1006551007404	Cl- binding residues [ion binding]; other site
1006551007405	pore gating glutamate residue; other site
1006551007406	dimer interface [polypeptide binding]; other site
1006551007407	H+/Cl- coupling transport residue; other site
1006551007408	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
1006551007409	hypothetical protein; Provisional; Region: PRK10578
1006551007410	UPF0126 domain; Region: UPF0126; pfam03458
1006551007411	UPF0126 domain; Region: UPF0126; pfam03458
1006551007412	vitamin B12-transporter protein BtuF; Provisional; Region: PRK03379
1006551007413	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
1006551007414	cobalamin binding residues [chemical binding]; other site
1006551007415	putative BtuC binding residues; other site
1006551007416	dimer interface [polypeptide binding]; other site
1006551007417	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
1006551007418	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
1006551007419	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
1006551007420	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1006551007421	Zn2+ binding site [ion binding]; other site
1006551007422	Mg2+ binding site [ion binding]; other site
1006551007423	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
1006551007424	serine endoprotease; Provisional; Region: PRK10942
1006551007425	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1006551007426	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1006551007427	protein binding site [polypeptide binding]; other site
1006551007428	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1006551007429	carbohydrate diacid transcriptional activator CdaR; Provisional; Region: PRK11477
1006551007430	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
1006551007431	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1006551007432	Viral enhancin protein; Region: Enhancin; pfam03272
1006551007433	hypothetical protein; Provisional; Region: PRK13677
1006551007434	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
1006551007435	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
1006551007436	trimer interface [polypeptide binding]; other site
1006551007437	active site
1006551007438	substrate binding site [chemical binding]; other site
1006551007439	CoA binding site [chemical binding]; other site
1006551007440	PII uridylyl-transferase; Provisional; Region: PRK05007
1006551007441	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1006551007442	metal binding triad; other site
1006551007443	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1006551007444	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1006551007445	Zn2+ binding site [ion binding]; other site
1006551007446	Mg2+ binding site [ion binding]; other site
1006551007447	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
1006551007448	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
1006551007449	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1006551007450	active site
1006551007451	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1006551007452	rRNA interaction site [nucleotide binding]; other site
1006551007453	S8 interaction site; other site
1006551007454	putative laminin-1 binding site; other site
1006551007455	elongation factor Ts; Provisional; Region: tsf; PRK09377
1006551007456	UBA/TS-N domain; Region: UBA; pfam00627
1006551007457	Elongation factor TS; Region: EF_TS; pfam00889
1006551007458	Elongation factor TS; Region: EF_TS; pfam00889
1006551007459	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1006551007460	putative nucleotide binding site [chemical binding]; other site
1006551007461	uridine monophosphate binding site [chemical binding]; other site
1006551007462	homohexameric interface [polypeptide binding]; other site
1006551007463	ribosome recycling factor; Reviewed; Region: frr; PRK00083
1006551007464	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1006551007465	hinge region; other site
1006551007466	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
1006551007467	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
1006551007468	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
1006551007469	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
1006551007470	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
1006551007471	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
1006551007472	catalytic residue [active]
1006551007473	putative FPP diphosphate  binding site; other site
1006551007474	putative FPP binding hydrophobic cleft; other site
1006551007475	dimer interface [polypeptide binding]; other site
1006551007476	putative IPP diphosphate binding site; other site
1006551007477	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
1006551007478	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1006551007479	zinc metallopeptidase RseP; Provisional; Region: PRK10779
1006551007480	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1006551007481	active site
1006551007482	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1006551007483	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1006551007484	protein binding site [polypeptide binding]; other site
1006551007485	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1006551007486	putative substrate binding region [chemical binding]; other site
1006551007487	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
1006551007488	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1006551007489	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1006551007490	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1006551007491	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1006551007492	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1006551007493	Surface antigen; Region: Bac_surface_Ag; pfam01103
1006551007494	periplasmic chaperone; Provisional; Region: PRK10780
1006551007495	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
1006551007496	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
1006551007497	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
1006551007498	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
1006551007499	trimer interface [polypeptide binding]; other site
1006551007500	active site
1006551007501	UDP-GlcNAc binding site [chemical binding]; other site
1006551007502	lipid binding site [chemical binding]; lipid-binding site
1006551007503	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1006551007504	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
1006551007505	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
1006551007506	active site
1006551007507	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
1006551007508	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
1006551007509	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
1006551007510	RNA/DNA hybrid binding site [nucleotide binding]; other site
1006551007511	active site
1006551007512	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
1006551007513	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
1006551007514	putative active site [active]
1006551007515	putative PHP Thumb interface [polypeptide binding]; other site
1006551007516	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1006551007517	generic binding surface II; other site
1006551007518	generic binding surface I; other site
1006551007519	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
1006551007520	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
1006551007521	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
1006551007522	Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some...; Region: chitinase_glyco_hydro_19; cd00325
1006551007523	putative sugar binding site [chemical binding]; other site
1006551007524	catalytic residues [active]
1006551007525	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cl17457
1006551007526	lysine decarboxylase LdcC; Provisional; Region: PRK15399
1006551007527	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1006551007528	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1006551007529	homodimer interface [polypeptide binding]; other site
1006551007530	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551007531	catalytic residue [active]
1006551007532	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1006551007533	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
1006551007534	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1006551007535	putative metal binding site [ion binding]; other site
1006551007536	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
1006551007537	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1006551007538	Ligand Binding Site [chemical binding]; other site
1006551007539	TilS substrate binding domain; Region: TilS; pfam09179
1006551007540	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
1006551007541	Rho-binding antiterminator; Provisional; Region: PRK11625
1006551007542	hypothetical protein; Provisional; Region: PRK04964
1006551007543	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4681
1006551007544	hypothetical protein; Provisional; Region: PRK09256
1006551007545	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
1006551007546	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
1006551007547	NlpE N-terminal domain; Region: NlpE; pfam04170
1006551007548	hypothetical protein; Provisional; Region: PRK11479
1006551007549	Orthopoxvirus protein of unknown function (DUF830); Region: DUF830; cl13998
1006551007550	prolyl-tRNA synthetase; Provisional; Region: PRK09194
1006551007551	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
1006551007552	dimer interface [polypeptide binding]; other site
1006551007553	motif 1; other site
1006551007554	active site
1006551007555	motif 2; other site
1006551007556	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
1006551007557	putative deacylase active site [active]
1006551007558	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1006551007559	active site
1006551007560	motif 3; other site
1006551007561	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
1006551007562	anticodon binding site; other site
1006551007563	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
1006551007564	homodimer interaction site [polypeptide binding]; other site
1006551007565	cofactor binding site; other site
1006551007566	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
1006551007567	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
1006551007568	lipoprotein, YaeC family; Region: TIGR00363
1006551007569	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551007570	dimer interface [polypeptide binding]; other site
1006551007571	conserved gate region; other site
1006551007572	ABC-ATPase subunit interface; other site
1006551007573	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
1006551007574	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1006551007575	Walker A/P-loop; other site
1006551007576	ATP binding site [chemical binding]; other site
1006551007577	Q-loop/lid; other site
1006551007578	ABC transporter signature motif; other site
1006551007579	Walker B; other site
1006551007580	D-loop; other site
1006551007581	H-loop/switch region; other site
1006551007582	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
1006551007583	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
1006551007584	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1006551007585	active site
1006551007586	motif I; other site
1006551007587	motif II; other site
1006551007588	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1006551007589	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1006551007590	active site
1006551007591	catalytic tetrad [active]
1006551007592	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551007593	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551007594	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1006551007595	dimerization interface [polypeptide binding]; other site
1006551007596	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1006551007597	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551007598	putative substrate translocation pore; other site
1006551007599	hypothetical protein; Provisional; Region: PRK05421
1006551007600	putative catalytic site [active]
1006551007601	putative metal binding site [ion binding]; other site
1006551007602	putative phosphate binding site [ion binding]; other site
1006551007603	putative catalytic site [active]
1006551007604	putative phosphate binding site [ion binding]; other site
1006551007605	putative metal binding site [ion binding]; other site
1006551007606	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1006551007607	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551007608	S-adenosylmethionine binding site [chemical binding]; other site
1006551007609	membrane-bound lytic murein transglycosylase D; Provisional; Region: mltD; PRK10783
1006551007610	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1006551007611	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1006551007612	catalytic residue [active]
1006551007613	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
1006551007614	ATP binding site [chemical binding]; other site
1006551007615	substrate binding site [chemical binding]; other site
1006551007616	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1006551007617	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1006551007618	hydroxyacylglutathione hydrolase; Provisional; Region: PRK10241
1006551007619	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551007620	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
1006551007621	RNA/DNA hybrid binding site [nucleotide binding]; other site
1006551007622	active site
1006551007623	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
1006551007624	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
1006551007625	active site
1006551007626	catalytic site [active]
1006551007627	substrate binding site [chemical binding]; other site
1006551007628	C-N hydrolase family amidase; Provisional; Region: PRK10438
1006551007629	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
1006551007630	putative active site [active]
1006551007631	catalytic triad [active]
1006551007632	dimer interface [polypeptide binding]; other site
1006551007633	multimer interface [polypeptide binding]; other site
1006551007634	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
1006551007635	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1006551007636	active site
1006551007637	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
1006551007638	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1006551007639	dimer interface [polypeptide binding]; other site
1006551007640	active site
1006551007641	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
1006551007642	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
1006551007643	putative active site [active]
1006551007644	putative dimer interface [polypeptide binding]; other site
1006551007645	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
1006551007646	Na(+)-translocating NADH-quinone reductase subunit A; Provisional; Region: PRK05352
1006551007647	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1006551007648	E3 interaction surface; other site
1006551007649	lipoyl attachment site [posttranslational modification]; other site
1006551007650	NQRA C-terminal domain; Region: NQRA_SLBB; pfam11973
1006551007651	Na(+)-translocating NADH-quinone reductase subunit B; Provisional; Region: PRK05349
1006551007652	Na(+)-translocating NADH-quinone reductase subunit C; Provisional; Region: PRK05346
1006551007653	NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit; Region: nqrC; TIGR01938
1006551007654	Na(+)-translocating NADH-quinone reductase subunit D; Validated; Region: PRK09292
1006551007655	Na(+)-translocating NADH-quinone reductase subunit E; Provisional; Region: PRK02830
1006551007656	Na(+)-translocating NADH-quinone reductase subunit F; Provisional; Region: PRK05464
1006551007657	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1006551007658	catalytic loop [active]
1006551007659	iron binding site [ion binding]; other site
1006551007660	Na+-translocating NADH:quinone oxidoreductase (Na+-NQR) FAD/NADH binding domain. (Na+-NQR) provides a means of storing redox reaction energy via the transmembrane translocation of Na2+ ions. The C-terminal domain resembles ferredoxin:NADP+ oxidoreductase; Region: NADH_quinone_reductase; cd06188
1006551007661	FAD binding pocket [chemical binding]; other site
1006551007662	FAD binding motif [chemical binding]; other site
1006551007663	phosphate binding motif [ion binding]; other site
1006551007664	beta-alpha-beta structure motif; other site
1006551007665	NAD binding pocket [chemical binding]; other site
1006551007666	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2991
1006551007667	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
1006551007668	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
1006551007669	active site
1006551007670	catalytic site [active]
1006551007671	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
1006551007672	active site
1006551007673	DNA polymerase IV; Validated; Region: PRK02406
1006551007674	DNA binding site [nucleotide binding]
1006551007675	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1006551007676	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1006551007677	Coenzyme A binding pocket [chemical binding]; other site
1006551007678	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
1006551007679	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
1006551007680	metal binding site [ion binding]; metal-binding site
1006551007681	dimer interface [polypeptide binding]; other site
1006551007682	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1006551007683	active site
1006551007684	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
1006551007685	DNA-binding transcriptional regulator Crl; Provisional; Region: PRK10984
1006551007686	putative acyl transferase; Provisional; Region: PRK10191
1006551007687	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1006551007688	trimer interface [polypeptide binding]; other site
1006551007689	active site
1006551007690	substrate binding site [chemical binding]; other site
1006551007691	CoA binding site [chemical binding]; other site
1006551007692	Beta-galactosidase; Region: Glyco_hydro_42; pfam02449
1006551007693	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1006551007694	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1006551007695	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1006551007696	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1006551007697	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
1006551007698	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1006551007699	active site
1006551007700	Polysaccharide biosynthesis protein; Region: Polysacc_synt_3; pfam13440
1006551007701	Chain length determinant protein; Region: Wzz; pfam02706
1006551007702	chain length determinant protein EpsF; Region: EpsF; TIGR03017
1006551007703	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1006551007704	AAA domain; Region: AAA_31; pfam13614
1006551007705	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1006551007706	putative polysaccharide export protein, PEP-CTERM sytem-associated; Region: pepcterm_export; TIGR03027
1006551007707	SLBB domain; Region: SLBB; pfam10531
1006551007708	Uncharacterized protein conserved in bacteria (DUF2320); Region: DUF2320; pfam10082
1006551007709	Undecaprenyl-phosphate glucose phosphotransferase; Region: WcaJ_sugtrans; TIGR03023
1006551007710	Bacterial sugar transferase; Region: Bac_transf; pfam02397
1006551007711	succinate-semialdehyde dehydrogenase I; Provisional; Region: gabD; PRK11241
1006551007712	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
1006551007713	tetramerization interface [polypeptide binding]; other site
1006551007714	NAD(P) binding site [chemical binding]; other site
1006551007715	catalytic residues [active]
1006551007716	Putative zinc ribbon domain; Region: Zn_ribbon_2; pfam12674
1006551007717	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
1006551007718	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1006551007719	N-terminal plug; other site
1006551007720	ligand-binding site [chemical binding]; other site
1006551007721	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1006551007722	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
1006551007723	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551007724	DNA-binding site [nucleotide binding]; DNA binding site
1006551007725	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1006551007726	D-mannonate oxidoreductase; Provisional; Region: PRK15037
1006551007727	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1006551007728	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1006551007729	mannonate dehydratase; Region: uxuA; TIGR00695
1006551007730	mannonate dehydratase; Provisional; Region: PRK03906
1006551007731	hypothetical protein; Provisional; Region: PRK13687
1006551007732	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
1006551007733	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1006551007734	Coenzyme A binding pocket [chemical binding]; other site
1006551007735	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1006551007736	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551007737	S-adenosylmethionine binding site [chemical binding]; other site
1006551007738	EamA-like transporter family; Region: EamA; pfam00892
1006551007739	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1006551007740	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1006551007741	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551007742	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
1006551007743	dimerization interface [polypeptide binding]; other site
1006551007744	substrate binding pocket [chemical binding]; other site
1006551007745	Carbohydrate-selective porin, OprB family; Region: OprB; cl17816
1006551007746	benzoate transport; Region: 2A0115; TIGR00895
1006551007747	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551007748	putative substrate translocation pore; other site
1006551007749	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551007750	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1006551007751	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1006551007752	DNA binding site [nucleotide binding]
1006551007753	domain linker motif; other site
1006551007754	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1006551007755	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1006551007756	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
1006551007757	inhibitor site; inhibition site
1006551007758	active site
1006551007759	dimer interface [polypeptide binding]; other site
1006551007760	catalytic residue [active]
1006551007761	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1006551007762	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1006551007763	Anaerobic c4-dicarboxylate membrane transporter; Region: DcuA_DcuB; cl01040
1006551007764	N-formimino-L-glutamate deiminase; Validated; Region: PRK09229
1006551007765	Metallo-dependent hydrolases, subgroup D is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_E; cd01313
1006551007766	active site
1006551007767	histidine utilization repressor, proteobacterial; Region: his_ut_repres; TIGR02018
1006551007768	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551007769	DNA-binding site [nucleotide binding]; DNA binding site
1006551007770	UTRA domain; Region: UTRA; pfam07702
1006551007771	HutD; Region: HutD; pfam05962
1006551007772	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
1006551007773	active sites [active]
1006551007774	tetramer interface [polypeptide binding]; other site
1006551007775	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1006551007776	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551007777	ABC-ATPase subunit interface; other site
1006551007778	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551007779	dimer interface [polypeptide binding]; other site
1006551007780	conserved gate region; other site
1006551007781	ABC-ATPase subunit interface; other site
1006551007782	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
1006551007783	glycine betaine/L-proline transport ATP binding subunit; Region: proV; TIGR01186
1006551007784	Walker A/P-loop; other site
1006551007785	ATP binding site [chemical binding]; other site
1006551007786	Q-loop/lid; other site
1006551007787	ABC transporter signature motif; other site
1006551007788	Walker B; other site
1006551007789	D-loop; other site
1006551007790	H-loop/switch region; other site
1006551007791	urocanate hydratase; Provisional; Region: PRK05414
1006551007792	Purine-cytosine permease and related proteins [Nucleotide transport and metabolism]; Region: CodB; COG1457
1006551007793	imidazolonepropionase; Validated; Region: PRK09356
1006551007794	Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296
1006551007795	active site
1006551007796	N-formylglutamate amidohydrolase; Region: FGase; cl01522
1006551007797	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551007798	putative substrate translocation pore; other site
1006551007799	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1006551007800	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
1006551007801	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1006551007802	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1006551007803	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1006551007804	AefR-like transcriptional repressor, C-terminal region; Region: TetR_C_7; pfam14246
1006551007805	Putative 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (THP succinyltransferase), C-terminal left-handed parallel alpha-helix (LbH) domain: This group is composed of mostly uncharacterized proteins containing an N-terminal...; Region: LbH_THP_succinylT_putative; cd04649
1006551007806	putative trimer interface [polypeptide binding]; other site
1006551007807	putative CoA binding site [chemical binding]; other site
1006551007808	Protein of unknown function (DUF1305); Region: DUF1305; pfam06996
1006551007809	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
1006551007810	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
1006551007811	Type VI secretion lipoprotein; Region: T6SS-SciN; pfam12790
1006551007812	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
1006551007813	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
1006551007814	PAAR motif; Region: PAAR_motif; pfam05488
1006551007815	Protein of unknown function (DUF3274); Region: DUF3274; pfam11678
1006551007816	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
1006551007817	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1006551007818	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1006551007819	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
1006551007820	Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; pfam10106
1006551007821	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
1006551007822	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
1006551007823	putative catalytic cysteine [active]
1006551007824	gamma-glutamyl kinase; Provisional; Region: PRK05429
1006551007825	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
1006551007826	nucleotide binding site [chemical binding]; other site
1006551007827	homotetrameric interface [polypeptide binding]; other site
1006551007828	putative phosphate binding site [ion binding]; other site
1006551007829	putative allosteric binding site; other site
1006551007830	PUA domain; Region: PUA; pfam01472
1006551007831	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1006551007832	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1006551007833	trimer interface [polypeptide binding]; other site
1006551007834	eyelet of channel; other site
1006551007835	NlpC/P60 family; Region: NLPC_P60; pfam00877
1006551007836	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551007837	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551007838	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1006551007839	dimerization interface [polypeptide binding]; other site
1006551007840	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
1006551007841	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551007842	membrane-bound complex binding site; other site
1006551007843	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551007844	dimer interface [polypeptide binding]; other site
1006551007845	ABC-type anion transport system, duplicated permease component [Inorganic ion transport and metabolism]; Region: COG4986
1006551007846	conserved gate region; other site
1006551007847	putative PBP binding loops; other site
1006551007848	ABC-ATPase subunit interface; other site
1006551007849	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551007850	dimer interface [polypeptide binding]; other site
1006551007851	conserved gate region; other site
1006551007852	putative PBP binding loops; other site
1006551007853	ABC-ATPase subunit interface; other site
1006551007854	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
1006551007855	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1006551007856	Walker A/P-loop; other site
1006551007857	ATP binding site [chemical binding]; other site
1006551007858	Q-loop/lid; other site
1006551007859	ABC transporter signature motif; other site
1006551007860	Walker B; other site
1006551007861	D-loop; other site
1006551007862	H-loop/switch region; other site
1006551007863	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
1006551007864	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1006551007865	catalytic residues [active]
1006551007866	Cupin domain; Region: Cupin_2; pfam07883
1006551007867	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1006551007868	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551007869	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1006551007870	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
1006551007871	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1006551007872	phosphonate ABC transporter, permease protein PhnE; Region: PhnE; TIGR01097
1006551007873	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551007874	dimer interface [polypeptide binding]; other site
1006551007875	conserved gate region; other site
1006551007876	putative PBP binding loops; other site
1006551007877	ABC-ATPase subunit interface; other site
1006551007878	phosphonate ABC transporter, permease protein PhnE; Region: PhnE; TIGR01097
1006551007879	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551007880	dimer interface [polypeptide binding]; other site
1006551007881	conserved gate region; other site
1006551007882	putative PBP binding loops; other site
1006551007883	ABC-ATPase subunit interface; other site
1006551007884	phosphonate ABC transporter, periplasmic phosphonate binding protein; Region: PhnD; TIGR03431
1006551007885	ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: COG3638
1006551007886	ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Region: ABC_PhnC_transporter; cd03256
1006551007887	Walker A/P-loop; other site
1006551007888	ATP binding site [chemical binding]; other site
1006551007889	Q-loop/lid; other site
1006551007890	ABC transporter signature motif; other site
1006551007891	Walker B; other site
1006551007892	D-loop; other site
1006551007893	H-loop/switch region; other site
1006551007894	DNA-binding transcriptional activator UhpA; Provisional; Region: PRK10360
1006551007895	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1006551007896	DNA binding residues [nucleotide binding]
1006551007897	putative fimbrial protein TcfA; Provisional; Region: PRK15308
1006551007898	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1006551007899	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1006551007900	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551007901	dimer interface [polypeptide binding]; other site
1006551007902	conserved gate region; other site
1006551007903	putative PBP binding loops; other site
1006551007904	ABC-ATPase subunit interface; other site
1006551007905	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1006551007906	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551007907	dimer interface [polypeptide binding]; other site
1006551007908	conserved gate region; other site
1006551007909	putative PBP binding loops; other site
1006551007910	ABC-ATPase subunit interface; other site
1006551007911	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1006551007912	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1006551007913	Walker A/P-loop; other site
1006551007914	ATP binding site [chemical binding]; other site
1006551007915	Q-loop/lid; other site
1006551007916	ABC transporter signature motif; other site
1006551007917	Walker B; other site
1006551007918	D-loop; other site
1006551007919	H-loop/switch region; other site
1006551007920	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1006551007921	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551007922	substrate binding pocket [chemical binding]; other site
1006551007923	membrane-bound complex binding site; other site
1006551007924	hinge residues; other site
1006551007925	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
1006551007926	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
1006551007927	Walker A/P-loop; other site
1006551007928	ATP binding site [chemical binding]; other site
1006551007929	Q-loop/lid; other site
1006551007930	ABC transporter signature motif; other site
1006551007931	Walker B; other site
1006551007932	D-loop; other site
1006551007933	H-loop/switch region; other site
1006551007934	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
1006551007935	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
1006551007936	Walker A/P-loop; other site
1006551007937	ATP binding site [chemical binding]; other site
1006551007938	Q-loop/lid; other site
1006551007939	ABC transporter signature motif; other site
1006551007940	Walker B; other site
1006551007941	D-loop; other site
1006551007942	H-loop/switch region; other site
1006551007943	ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177
1006551007944	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
1006551007945	TM-ABC transporter signature motif; other site
1006551007946	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1006551007947	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
1006551007948	TM-ABC transporter signature motif; other site
1006551007949	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1006551007950	Type I periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_ligand_binding_like_12; cd06347
1006551007951	putative ligand binding site [chemical binding]; other site
1006551007952	ethanolamine ammonia-lyase small subunit; Provisional; Region: PRK05465
1006551007953	ethanolamine ammonia lyase large subunit; Provisional; Region: PRK15067
1006551007954	Ethanolamine ammonia lyase large subunit (EutB); Region: EutB; pfam06751
1006551007955	ethanolamine permease; Region: 2A0305; TIGR00908
1006551007956	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
1006551007957	Glycosyl hydrolases family 28; Region: Glyco_hydro_28; pfam00295
1006551007958	S-methylmethionine transporter; Provisional; Region: PRK11387
1006551007959	homocysteine methyltransferase; Provisional; Region: mmuM; PRK09485
1006551007960	Homocysteine S-methyltransferase; Region: S-methyl_trans; pfam02574
1006551007961	ferric transporter ATP-binding subunit; Provisional; Region: fbpC; PRK11432
1006551007962	ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259
1006551007963	Walker A/P-loop; other site
1006551007964	ATP binding site [chemical binding]; other site
1006551007965	Q-loop/lid; other site
1006551007966	ABC transporter signature motif; other site
1006551007967	Walker B; other site
1006551007968	D-loop; other site
1006551007969	H-loop/switch region; other site
1006551007970	TOBE domain; Region: TOBE_2; pfam08402
1006551007971	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
1006551007972	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551007973	dimer interface [polypeptide binding]; other site
1006551007974	conserved gate region; other site
1006551007975	putative PBP binding loops; other site
1006551007976	ABC-ATPase subunit interface; other site
1006551007977	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551007978	dimer interface [polypeptide binding]; other site
1006551007979	conserved gate region; other site
1006551007980	putative PBP binding loops; other site
1006551007981	ABC-ATPase subunit interface; other site
1006551007982	Chemotaxis-inhibiting protein CHIPS; Region: CHIPS; cl10100
1006551007983	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1006551007984	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
1006551007985	regulatory protein UhpC; Provisional; Region: PRK11663
1006551007986	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551007987	putative substrate translocation pore; other site
1006551007988	Signal transduction histidine kinase, glucose-6-phosphate specific [Signal transduction mechanisms]; Region: UhpB; COG3851
1006551007989	MASE1; Region: MASE1; pfam05231
1006551007990	Histidine kinase; Region: HisKA_3; pfam07730
1006551007991	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551007992	ATP binding site [chemical binding]; other site
1006551007993	Mg2+ binding site [ion binding]; other site
1006551007994	G-X-G motif; other site
1006551007995	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1006551007996	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551007997	active site
1006551007998	phosphorylation site [posttranslational modification]
1006551007999	intermolecular recognition site; other site
1006551008000	dimerization interface [polypeptide binding]; other site
1006551008001	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1006551008002	DNA binding residues [nucleotide binding]
1006551008003	dimerization interface [polypeptide binding]; other site
1006551008004	ABC-type taurine transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: TauA; COG4521
1006551008005	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551008006	substrate binding pocket [chemical binding]; other site
1006551008007	membrane-bound complex binding site; other site
1006551008008	hinge residues; other site
1006551008009	taurine transporter ATP-binding subunit; Provisional; Region: tauB; PRK11248
1006551008010	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1006551008011	Walker A/P-loop; other site
1006551008012	ATP binding site [chemical binding]; other site
1006551008013	Q-loop/lid; other site
1006551008014	ABC transporter signature motif; other site
1006551008015	Walker B; other site
1006551008016	D-loop; other site
1006551008017	H-loop/switch region; other site
1006551008018	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1006551008019	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551008020	dimer interface [polypeptide binding]; other site
1006551008021	conserved gate region; other site
1006551008022	putative PBP binding loops; other site
1006551008023	ABC-ATPase subunit interface; other site
1006551008024	Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175
1006551008025	taurine dioxygenase; Reviewed; Region: tauD; PRK09553
1006551008026	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cl17185
1006551008027	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1006551008028	putative acyl-acceptor binding pocket; other site
1006551008029	Acetyltransferase (GNAT) domain; Region: Acetyltransf_5; pfam13444
1006551008030	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG1943
1006551008031	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
1006551008032	dimer interface [polypeptide binding]; other site
1006551008033	active site
1006551008034	Schiff base residues; other site
1006551008035	beta-lactam binding protein AmpH; Provisional; Region: PRK10662
1006551008036	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1006551008037	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cl00220
1006551008038	Isochorismatase family; Region: Isochorismatase; pfam00857
1006551008039	catalytic triad [active]
1006551008040	conserved cis-peptide bond; other site
1006551008041	microcin B17 transporter; Reviewed; Region: PRK11098
1006551008042	Protein of unknown function (DUF1615); Region: DUF1615; pfam07759
1006551008043	Protein of unknown function (DUF2755); Region: DUF2755; pfam10954
1006551008044	Protein of unknown function (DUF2754); Region: DUF2754; pfam10953
1006551008045	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
1006551008046	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1006551008047	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
1006551008048	Extensin-like protein C-terminus; Region: Extensin-like_C; pfam06904
1006551008049	drug efflux system protein MdtG; Provisional; Region: PRK09874
1006551008050	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551008051	putative substrate translocation pore; other site
1006551008052	gluconate 5-dehydrogenase; Provisional; Region: PRK08085
1006551008053	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1006551008054	NADP binding site [chemical binding]; other site
1006551008055	homodimer interface [polypeptide binding]; other site
1006551008056	active site
1006551008057	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551008058	D-galactonate transporter; Region: 2A0114; TIGR00893
1006551008059	putative substrate translocation pore; other site
1006551008060	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
1006551008061	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1006551008062	DNA binding site [nucleotide binding]
1006551008063	domain linker motif; other site
1006551008064	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1006551008065	putative dimerization interface [polypeptide binding]; other site
1006551008066	putative ligand binding site [chemical binding]; other site
1006551008067	anti-RssB factor; Provisional; Region: PRK10244
1006551008068	alkaline phosphatase; Provisional; Region: PRK10518
1006551008069	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cd00016
1006551008070	active site
1006551008071	dimer interface [polypeptide binding]; other site
1006551008072	psiF repeat; Region: PsiF_repeat; pfam07769
1006551008073	psiF repeat; Region: PsiF_repeat; pfam07769
1006551008074	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
1006551008075	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
1006551008076	hypothetical protein; Validated; Region: PRK00124
1006551008077	Uncharacterized protein conserved in bacteria (DUF2076); Region: DUF2076; pfam09849
1006551008078	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
1006551008079	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1006551008080	ADP binding site [chemical binding]; other site
1006551008081	magnesium binding site [ion binding]; other site
1006551008082	putative shikimate binding site; other site
1006551008083	hypothetical protein; Provisional; Region: PRK10380
1006551008084	hypothetical protein; Provisional; Region: PRK10481
1006551008085	hypothetical protein; Provisional; Region: PRK10579
1006551008086	recombination associated protein; Reviewed; Region: rdgC; PRK00321
1006551008087	fructokinase; Reviewed; Region: PRK09557
1006551008088	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1006551008089	nucleotide binding site [chemical binding]; other site
1006551008090	Domain of unknown function (DUF4406); Region: DUF4406; pfam14359
1006551008091	exonuclease subunit SbcC; Provisional; Region: PRK10246
1006551008092	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551008093	Walker A/P-loop; other site
1006551008094	ATP binding site [chemical binding]; other site
1006551008095	Q-loop/lid; other site
1006551008096	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551008097	ABC transporter signature motif; other site
1006551008098	Walker B; other site
1006551008099	D-loop; other site
1006551008100	H-loop/switch region; other site
1006551008101	exonuclease subunit SbcD; Provisional; Region: PRK10966
1006551008102	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
1006551008103	active site
1006551008104	metal binding site [ion binding]; metal-binding site
1006551008105	DNA binding site [nucleotide binding]
1006551008106	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
1006551008107	transcriptional regulator PhoB; Provisional; Region: PRK10161
1006551008108	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551008109	active site
1006551008110	phosphorylation site [posttranslational modification]
1006551008111	intermolecular recognition site; other site
1006551008112	dimerization interface [polypeptide binding]; other site
1006551008113	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1006551008114	DNA binding site [nucleotide binding]
1006551008115	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
1006551008116	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
1006551008117	PAS domain; Region: PAS; smart00091
1006551008118	putative active site [active]
1006551008119	heme pocket [chemical binding]; other site
1006551008120	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1006551008121	dimer interface [polypeptide binding]; other site
1006551008122	phosphorylation site [posttranslational modification]
1006551008123	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551008124	ATP binding site [chemical binding]; other site
1006551008125	Mg2+ binding site [ion binding]; other site
1006551008126	G-X-G motif; other site
1006551008127	branched-chain amino acid transport system 2 carrier protein BrnQ; Provisional; Region: PRK15433
1006551008128	putative proline-specific permease; Provisional; Region: proY; PRK10580
1006551008129	Spore germination protein; Region: Spore_permease; cl17796
1006551008130	maltodextrin glucosidase; Provisional; Region: PRK10785
1006551008131	Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus; Region: E_set; cl09101
1006551008132	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
1006551008133	active site
1006551008134	homodimer interface [polypeptide binding]; other site
1006551008135	catalytic site [active]
1006551008136	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551008137	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551008138	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1006551008139	dimerization interface [polypeptide binding]; other site
1006551008140	Isochorismatase family; Region: Isochorismatase; pfam00857
1006551008141	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
1006551008142	catalytic triad [active]
1006551008143	dimer interface [polypeptide binding]; other site
1006551008144	conserved cis-peptide bond; other site
1006551008145	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3224
1006551008146	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
1006551008147	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
1006551008148	active site
1006551008149	Flagellar hook-length control protein FliK; Region: Flg_hook; cl17777
1006551008150	Predicted membrane protein (DUF2339); Region: DUF2339; pfam10101
1006551008151	Protein of unknown function (DUF3999); Region: DUF3999; pfam13163
1006551008152	peroxidase; Provisional; Region: PRK15000
1006551008153	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1006551008154	dimer interface [polypeptide binding]; other site
1006551008155	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1006551008156	catalytic triad [active]
1006551008157	peroxidatic and resolving cysteines [active]
1006551008158	acyl carrier protein phosphodiesterase; Provisional; Region: PRK10045
1006551008159	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
1006551008160	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1006551008161	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1006551008162	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
1006551008163	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
1006551008164	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
1006551008165	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
1006551008166	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1006551008167	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
1006551008168	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
1006551008169	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1006551008170	Protein export membrane protein; Region: SecD_SecF; pfam02355
1006551008171	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
1006551008172	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1006551008173	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cd01066
1006551008174	active site
1006551008175	N-terminal domain of Streptomyces griseus SgaA (suppression of growth disturbance caused by A-factor at a high concentration under high osmolality during early growth phase), and similar domains; Region: SgaA_N_like; cd07247
1006551008176	Predicted transcriptional regulator [Transcription]; Region: COG2378
1006551008177	HTH domain; Region: HTH_11; pfam08279
1006551008178	WYL domain; Region: WYL; pfam13280
1006551008179	nucleoside-specific channel-forming protein Tsx; Provisional; Region: PRK15106
1006551008180	hypothetical protein; Provisional; Region: PRK11530
1006551008181	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
1006551008182	ATP cone domain; Region: ATP-cone; pfam03477
1006551008183	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
1006551008184	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
1006551008185	catalytic motif [active]
1006551008186	Zn binding site [ion binding]; other site
1006551008187	riboflavin-specific deaminase C-terminal domain; Region: ribD_Cterm; TIGR00227
1006551008188	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
1006551008189	homopentamer interface [polypeptide binding]; other site
1006551008190	active site
1006551008191	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
1006551008192	putative RNA binding site [nucleotide binding]; other site
1006551008193	thiamine monophosphate kinase; Provisional; Region: PRK05731
1006551008194	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
1006551008195	ATP binding site [chemical binding]; other site
1006551008196	dimerization interface [polypeptide binding]; other site
1006551008197	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
1006551008198	tetramer interfaces [polypeptide binding]; other site
1006551008199	binuclear metal-binding site [ion binding]; other site
1006551008200	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1006551008201	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1006551008202	active site
1006551008203	catalytic tetrad [active]
1006551008204	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
1006551008205	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
1006551008206	TPP-binding site; other site
1006551008207	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1006551008208	PYR/PP interface [polypeptide binding]; other site
1006551008209	dimer interface [polypeptide binding]; other site
1006551008210	TPP binding site [chemical binding]; other site
1006551008211	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1006551008212	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1006551008213	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1006551008214	substrate binding pocket [chemical binding]; other site
1006551008215	chain length determination region; other site
1006551008216	substrate-Mg2+ binding site; other site
1006551008217	catalytic residues [active]
1006551008218	aspartate-rich region 1; other site
1006551008219	active site lid residues [active]
1006551008220	aspartate-rich region 2; other site
1006551008221	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
1006551008222	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
1006551008223	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
1006551008224	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
1006551008225	Ligand Binding Site [chemical binding]; other site
1006551008226	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1006551008227	active site residue [active]
1006551008228	oxidative-stress-resistance chaperone; Provisional; Region: PRK11574
1006551008229	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
1006551008230	conserved cys residue [active]
1006551008231	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
1006551008232	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1006551008233	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
1006551008234	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
1006551008235	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
1006551008236	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551008237	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1006551008238	putative substrate translocation pore; other site
1006551008239	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1006551008240	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1006551008241	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1006551008242	MFS/sugar transport protein; Region: MFS_2; pfam13347
1006551008243	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551008244	putative substrate translocation pore; other site
1006551008245	benzoate transport; Region: 2A0115; TIGR00895
1006551008246	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551008247	putative substrate translocation pore; other site
1006551008248	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
1006551008249	putative FAD-binding dehydrogenase; Reviewed; Region: PRK06134
1006551008250	Predicted oxidoreductase [General function prediction only]; Region: COG3573
1006551008251	NIPSNAP; Region: NIPSNAP; pfam07978
1006551008252	putative FAD-binding dehydrogenase; Reviewed; Region: PRK12843
1006551008253	putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834
1006551008254	Shikimate 5-dehydrogenase [Amino acid transport and metabolism]; Region: AroE; COG0169
1006551008255	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1006551008256	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1006551008257	shikimate binding site; other site
1006551008258	NAD(P) binding site [chemical binding]; other site
1006551008259	beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family; Region: pcaR_pcaU; TIGR02431
1006551008260	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1006551008261	Bacterial transcriptional regulator; Region: IclR; pfam01614
1006551008262	protoheme IX farnesyltransferase; Provisional; Region: PRK13362
1006551008263	UbiA prenyltransferase family; Region: UbiA; pfam01040
1006551008264	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
1006551008265	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
1006551008266	Subunit I/III interface [polypeptide binding]; other site
1006551008267	Subunit III/IV interface [polypeptide binding]; other site
1006551008268	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
1006551008269	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
1006551008270	D-pathway; other site
1006551008271	Putative ubiquinol binding site [chemical binding]; other site
1006551008272	Low-spin heme (heme b) binding site [chemical binding]; other site
1006551008273	Putative water exit pathway; other site
1006551008274	Binuclear center (heme o3/CuB) [ion binding]; other site
1006551008275	K-pathway; other site
1006551008276	Putative proton exit pathway; other site
1006551008277	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
1006551008278	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
1006551008279	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
1006551008280	muropeptide transporter; Reviewed; Region: ampG; PRK11902
1006551008281	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551008282	putative substrate translocation pore; other site
1006551008283	hypothetical protein; Provisional; Region: PRK11627
1006551008284	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
1006551008285	Uncharacterized lipoprotein; Region: Lipoprotein_16; pfam03923
1006551008286	transcriptional regulator BolA; Provisional; Region: PRK11628
1006551008287	trigger factor; Provisional; Region: tig; PRK01490
1006551008288	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1006551008289	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1006551008290	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
1006551008291	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1006551008292	oligomer interface [polypeptide binding]; other site
1006551008293	active site residues [active]
1006551008294	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1006551008295	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
1006551008296	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1006551008297	Walker A motif; other site
1006551008298	ATP binding site [chemical binding]; other site
1006551008299	Walker B motif; other site
1006551008300	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1006551008301	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
1006551008302	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1006551008303	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1006551008304	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1006551008305	Walker A motif; other site
1006551008306	ATP binding site [chemical binding]; other site
1006551008307	Walker B motif; other site
1006551008308	arginine finger; other site
1006551008309	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1006551008310	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1006551008311	IHF dimer interface [polypeptide binding]; other site
1006551008312	IHF - DNA interface [nucleotide binding]; other site
1006551008313	periplasmic folding chaperone; Provisional; Region: PRK10788
1006551008314	SurA N-terminal domain; Region: SurA_N_3; cl07813
1006551008315	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
1006551008316	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
1006551008317	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786
1006551008318	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1006551008319	active site
1006551008320	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
1006551008321	Ligand Binding Site [chemical binding]; other site
1006551008322	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
1006551008323	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1006551008324	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
1006551008325	thiamin pyrimidine pyrophosphate hydrolase; Provisional; Region: PRK15126
1006551008326	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1006551008327	active site
1006551008328	motif I; other site
1006551008329	motif II; other site
1006551008330	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
1006551008331	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1006551008332	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
1006551008333	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1006551008334	catalytic residue [active]
1006551008335	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1006551008336	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1006551008337	putative DNA binding site [nucleotide binding]; other site
1006551008338	putative Zn2+ binding site [ion binding]; other site
1006551008339	AsnC family; Region: AsnC_trans_reg; pfam01037
1006551008340	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
1006551008341	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1006551008342	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551008343	Walker A/P-loop; other site
1006551008344	ATP binding site [chemical binding]; other site
1006551008345	Q-loop/lid; other site
1006551008346	ABC transporter signature motif; other site
1006551008347	Walker B; other site
1006551008348	D-loop; other site
1006551008349	H-loop/switch region; other site
1006551008350	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
1006551008351	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1006551008352	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551008353	Walker A/P-loop; other site
1006551008354	ATP binding site [chemical binding]; other site
1006551008355	Q-loop/lid; other site
1006551008356	ABC transporter signature motif; other site
1006551008357	Walker B; other site
1006551008358	D-loop; other site
1006551008359	H-loop/switch region; other site
1006551008360	nitrogen regulatory protein P-II 2; Provisional; Region: PRK10665
1006551008361	Nitrogen regulatory protein P-II; Region: P-II; smart00938
1006551008362	ammonium transporter; Provisional; Region: PRK10666
1006551008363	acyl-CoA thioesterase II; Provisional; Region: PRK10526
1006551008364	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
1006551008365	active site
1006551008366	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
1006551008367	catalytic triad [active]
1006551008368	dimer interface [polypeptide binding]; other site
1006551008369	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3126
1006551008370	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1006551008371	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1006551008372	DNA binding site [nucleotide binding]
1006551008373	active site
1006551008374	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1006551008375	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551008376	DNA-binding site [nucleotide binding]; DNA binding site
1006551008377	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1006551008378	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551008379	homodimer interface [polypeptide binding]; other site
1006551008380	catalytic residue [active]
1006551008381	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1006551008382	Predicted membrane protein [Function unknown]; Region: COG2364
1006551008383	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1006551008384	Protein of unknown function (DUF1428); Region: DUF1428; cl02319
1006551008385	nickel/cobalt efflux protein RcnA; Provisional; Region: PRK10019
1006551008386	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
1006551008387	putative metal binding site [ion binding]; other site
1006551008388	putative homodimer interface [polypeptide binding]; other site
1006551008389	putative homotetramer interface [polypeptide binding]; other site
1006551008390	putative homodimer-homodimer interface [polypeptide binding]; other site
1006551008391	putative allosteric switch controlling residues; other site
1006551008392	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
1006551008393	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1006551008394	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1006551008395	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1006551008396	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
1006551008397	Walker A/P-loop; other site
1006551008398	ATP binding site [chemical binding]; other site
1006551008399	Q-loop/lid; other site
1006551008400	ABC transporter signature motif; other site
1006551008401	Walker B; other site
1006551008402	D-loop; other site
1006551008403	H-loop/switch region; other site
1006551008404	TOBE domain; Region: TOBE_2; pfam08402
1006551008405	Maltose-binding periplasmic proteins/domains [Carbohydrate transport and metabolism]; Region: MalE; COG2182
1006551008406	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1006551008407	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551008408	dimer interface [polypeptide binding]; other site
1006551008409	conserved gate region; other site
1006551008410	ABC-ATPase subunit interface; other site
1006551008411	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1006551008412	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551008413	dimer interface [polypeptide binding]; other site
1006551008414	conserved gate region; other site
1006551008415	putative PBP binding loops; other site
1006551008416	ABC-ATPase subunit interface; other site
1006551008417	Arabinogalactan endo-1,4-beta-galactosidase [Carbohydrate transport and metabolism]; Region: COG3867
1006551008418	Beta-galactosidase [Carbohydrate transport and metabolism]; Region: LacA; COG1874
1006551008419	Beta-galactosidase; Region: Glyco_hydro_42; pfam02449
1006551008420	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
1006551008421	Beta-galactosidase C-terminal domain; Region: Glyco_hydro_42C; pfam08533
1006551008422	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1006551008423	active site turn [active]
1006551008424	phosphorylation site [posttranslational modification]
1006551008425	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
1006551008426	trimer interface; other site
1006551008427	sugar binding site [chemical binding]; other site
1006551008428	lac repressor; Reviewed; Region: lacI; PRK09526
1006551008429	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1006551008430	DNA binding site [nucleotide binding]
1006551008431	domain linker motif; other site
1006551008432	Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_LacI; cd01574
1006551008433	ligand binding site [chemical binding]; other site
1006551008434	dimerization interface (open form) [polypeptide binding]; other site
1006551008435	dimerization interface (closed form) [polypeptide binding]; other site
1006551008436	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
1006551008437	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
1006551008438	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1006551008439	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1006551008440	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1006551008441	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551008442	DNA-binding site [nucleotide binding]; DNA binding site
1006551008443	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1006551008444	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551008445	homodimer interface [polypeptide binding]; other site
1006551008446	catalytic residue [active]
1006551008447	sigma70 family sigma factor YlaC; Region: YlaC; pfam10777
1006551008448	potential frameshift: common BLAST hit: gi|238893428|ref|YP_002918162.1| maltose O-acetyltransferase
1006551008449	gene expression modulator; Provisional; Region: PRK10945
1006551008450	Hha toxicity attenuator; Provisional; Region: PRK10667
1006551008451	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
1006551008452	Protein export membrane protein; Region: SecD_SecF; cl14618
1006551008453	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
1006551008454	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1006551008455	HlyD family secretion protein; Region: HlyD_3; pfam13437
1006551008456	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
1006551008457	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1006551008458	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
1006551008459	hypothetical protein; Provisional; Region: PRK11281
1006551008460	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
1006551008461	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1006551008462	putative transposase; Provisional; Region: PRK09857
1006551008463	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1006551008464	hypothetical protein; Provisional; Region: PRK11038
1006551008465	primosomal replication protein N''; Provisional; Region: PRK10093
1006551008466	hypothetical protein; Provisional; Region: PRK10527
1006551008467	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1006551008468	active site
1006551008469	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994
1006551008470	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1006551008471	Walker A motif; other site
1006551008472	ATP binding site [chemical binding]; other site
1006551008473	Walker B motif; other site
1006551008474	arginine finger; other site
1006551008475	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
1006551008476	DNA polymerase III subunits tau domain IV DnaB-binding; Region: DNA_pol3_tau_4; pfam12168
1006551008477	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
1006551008478	hypothetical protein; Validated; Region: PRK00153
1006551008479	recombination protein RecR; Reviewed; Region: recR; PRK00076
1006551008480	RecR protein; Region: RecR; pfam02132
1006551008481	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
1006551008482	putative active site [active]
1006551008483	putative metal-binding site [ion binding]; other site
1006551008484	tetramer interface [polypeptide binding]; other site
1006551008485	heat shock protein 90; Provisional; Region: PRK05218
1006551008486	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551008487	ATP binding site [chemical binding]; other site
1006551008488	Mg2+ binding site [ion binding]; other site
1006551008489	G-X-G motif; other site
1006551008490	adenylate kinase; Reviewed; Region: adk; PRK00279
1006551008491	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1006551008492	AMP-binding site [chemical binding]; other site
1006551008493	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1006551008494	ferrochelatase; Reviewed; Region: hemH; PRK00035
1006551008495	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
1006551008496	C-terminal domain interface [polypeptide binding]; other site
1006551008497	active site
1006551008498	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
1006551008499	active site
1006551008500	N-terminal domain interface [polypeptide binding]; other site
1006551008501	inosine/guanosine kinase; Provisional; Region: PRK15074
1006551008502	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1006551008503	putative cation:proton antiport protein; Provisional; Region: PRK10669
1006551008504	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
1006551008505	TrkA-N domain; Region: TrkA_N; pfam02254
1006551008506	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551008507	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1006551008508	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551008509	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
1006551008510	Escherichia coli UshA and related proteins, N-terminal metallophosphatase domain; Region: MPP_UshA_N; cd07405
1006551008511	active site
1006551008512	metal binding site [ion binding]; metal-binding site
1006551008513	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1006551008514	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
1006551008515	putative deacylase active site [active]
1006551008516	TraB family; Region: TraB; cl12050
1006551008517	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1006551008518	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
1006551008519	Gram-negative bacterial tonB protein; Region: TonB; cl10048
1006551008520	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
1006551008521	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1006551008522	N-terminal plug; other site
1006551008523	ligand-binding site [chemical binding]; other site
1006551008524	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
1006551008525	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
1006551008526	PLD-like domain; Region: PLDc_2; pfam13091
1006551008527	putative active site [active]
1006551008528	catalytic site [active]
1006551008529	Putative catalytic domain, repeat 2, of vertebrate phospholipases, PLD3, PLD4 and PLD5, viral envelope proteins K4 and p37, and similar proteins; Region: PLDc_vPLD3_4_5_like_2; cd09107
1006551008530	PLD-like domain; Region: PLDc_2; pfam13091
1006551008531	putative active site [active]
1006551008532	putative catalytic site [active]
1006551008533	copper exporting ATPase; Provisional; Region: copA; PRK10671
1006551008534	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1006551008535	metal-binding site [ion binding]
1006551008536	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1006551008537	metal-binding site [ion binding]
1006551008538	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1006551008539	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1006551008540	motif II; other site
1006551008541	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
1006551008542	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
1006551008543	DNA binding residues [nucleotide binding]
1006551008544	dimer interface [polypeptide binding]; other site
1006551008545	copper binding site [ion binding]; other site
1006551008546	Protein of unknown function (DUF3142); Region: DUF3142; pfam11340
1006551008547	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
1006551008548	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1006551008549	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
1006551008550	putative ABC transporter ATP-binding protein YbbL; Provisional; Region: PRK10247
1006551008551	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1006551008552	Walker A/P-loop; other site
1006551008553	ATP binding site [chemical binding]; other site
1006551008554	Q-loop/lid; other site
1006551008555	ABC transporter signature motif; other site
1006551008556	Walker B; other site
1006551008557	D-loop; other site
1006551008558	H-loop/switch region; other site
1006551008559	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG0390
1006551008560	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
1006551008561	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
1006551008562	oxidoreductase; Provisional; Region: PRK08017
1006551008563	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
1006551008564	NADP binding site [chemical binding]; other site
1006551008565	active site
1006551008566	steroid binding site; other site
1006551008567	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
1006551008568	active site
1006551008569	catalytic triad [active]
1006551008570	oxyanion hole [active]
1006551008571	switch loop; other site
1006551008572	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
1006551008573	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1006551008574	Walker A/P-loop; other site
1006551008575	ATP binding site [chemical binding]; other site
1006551008576	Q-loop/lid; other site
1006551008577	ABC transporter signature motif; other site
1006551008578	Walker B; other site
1006551008579	D-loop; other site
1006551008580	H-loop/switch region; other site
1006551008581	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
1006551008582	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
1006551008583	putative monooxygenase; Provisional; Region: PRK11118
1006551008584	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1006551008585	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1006551008586	tRNA 2-selenouridine synthase; Provisional; Region: PRK11784
1006551008587	Member of the Rhodanese Homology Domain superfamily. This CD includes several putative ATP /GTP binding proteins including E. coli YbbB; Region: RHOD_YbbB; cd01520
1006551008588	active site residue [active]
1006551008589	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
1006551008590	ATP-grasp domain; Region: ATP-grasp; pfam02222
1006551008591	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
1006551008592	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
1006551008593	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1006551008594	putative active site [active]
1006551008595	putative metal binding site [ion binding]; other site
1006551008596	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
1006551008597	substrate binding site [chemical binding]; other site
1006551008598	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1006551008599	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1006551008600	active site
1006551008601	HIGH motif; other site
1006551008602	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1006551008603	KMSKS motif; other site
1006551008604	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
1006551008605	tRNA binding surface [nucleotide binding]; other site
1006551008606	anticodon binding site; other site
1006551008607	ribosome-associated protein; Provisional; Region: PRK11507
1006551008608	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
1006551008609	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1006551008610	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1006551008611	homodimer interface [polypeptide binding]; other site
1006551008612	NADP binding site [chemical binding]; other site
1006551008613	substrate binding site [chemical binding]; other site
1006551008614	Putative FMN-binding domain; Region: FMN_bind_2; pfam04299
1006551008615	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1006551008616	Endopygalactorunase [Cell envelope biogenesis, outer membrane]; Region: PGU1; COG5434
1006551008617	Interdomain contacts; other site
1006551008618	Cytokine receptor motif; other site
1006551008619	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
1006551008620	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1006551008621	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1006551008622	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551008623	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1006551008624	dimerization interface [polypeptide binding]; other site
1006551008625	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
1006551008626	DNA-binding transcriptional activator CadC; Provisional; Region: PRK10153
1006551008627	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1006551008628	DNA binding site [nucleotide binding]
1006551008629	lysine/cadaverine antiporter; Provisional; Region: cadB; PRK10435
1006551008630	lysine decarboxylase CadA; Provisional; Region: PRK15400
1006551008631	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1006551008632	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1006551008633	homodimer interface [polypeptide binding]; other site
1006551008634	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551008635	catalytic residue [active]
1006551008636	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1006551008637	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1006551008638	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551008639	putative substrate translocation pore; other site
1006551008640	POT family; Region: PTR2; pfam00854
1006551008641	lysyl-tRNA synthetase; Reviewed; Region: PRK12445
1006551008642	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1006551008643	dimer interface [polypeptide binding]; other site
1006551008644	putative anticodon binding site; other site
1006551008645	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1006551008646	motif 1; other site
1006551008647	active site
1006551008648	motif 2; other site
1006551008649	motif 3; other site
1006551008650	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
1006551008651	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1006551008652	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1006551008653	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1006551008654	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1006551008655	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1006551008656	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1006551008657	DNA binding site [nucleotide binding]
1006551008658	Periplasmic sugar-binding domain of uncharacterized transport systems; Region: PBP1_uncharacterized_sugar_binding; cd06307
1006551008659	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1006551008660	putative ligand binding site [chemical binding]; other site
1006551008661	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
1006551008662	Periplasmic binding proteins specific to rhizopines; Region: PBP1_rhizopine_binding_like; cd06301
1006551008663	putative ligand binding site [chemical binding]; other site
1006551008664	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1006551008665	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1006551008666	Walker A/P-loop; other site
1006551008667	ATP binding site [chemical binding]; other site
1006551008668	Q-loop/lid; other site
1006551008669	ABC transporter signature motif; other site
1006551008670	Walker B; other site
1006551008671	D-loop; other site
1006551008672	H-loop/switch region; other site
1006551008673	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1006551008674	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1006551008675	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1006551008676	TM-ABC transporter signature motif; other site
1006551008677	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
1006551008678	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1006551008679	active site turn [active]
1006551008680	phosphorylation site [posttranslational modification]
1006551008681	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1006551008682	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
1006551008683	HPr interaction site; other site
1006551008684	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1006551008685	active site
1006551008686	phosphorylation site [posttranslational modification]
1006551008687	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1006551008688	beta-galactosidase; Region: BGL; TIGR03356
1006551008689	transcriptional antiterminator BglG; Provisional; Region: PRK09772
1006551008690	CAT RNA binding domain; Region: CAT_RBD; smart01061
1006551008691	PRD domain; Region: PRD; pfam00874
1006551008692	PRD domain; Region: PRD; pfam00874
1006551008693	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1006551008694	non-specific DNA binding site [nucleotide binding]; other site
1006551008695	salt bridge; other site
1006551008696	sequence-specific DNA binding site [nucleotide binding]; other site
1006551008697	HipA N-terminal domain; Region: Couple_hipA; cl11853
1006551008698	HipA-like N-terminal domain; Region: HipA_N; pfam07805
1006551008699	HipA-like C-terminal domain; Region: HipA_C; pfam07804
1006551008700	D-fructose-responsive transcription factor; Region: fruct_sucro_rep; TIGR02417
1006551008701	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1006551008702	DNA binding site [nucleotide binding]
1006551008703	domain linker motif; other site
1006551008704	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
1006551008705	dimerization interface [polypeptide binding]; other site
1006551008706	ligand binding site [chemical binding]; other site
1006551008707	sucrose-6-phosphate hydrolase; Region: scrB_fam; TIGR01322
1006551008708	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
1006551008709	substrate binding [chemical binding]; other site
1006551008710	active site
1006551008711	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
1006551008712	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
1006551008713	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1006551008714	active site turn [active]
1006551008715	phosphorylation site [posttranslational modification]
1006551008716	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1006551008717	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
1006551008718	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
1006551008719	trimer interface; other site
1006551008720	sugar binding site [chemical binding]; other site
1006551008721	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1006551008722	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
1006551008723	putative substrate binding site [chemical binding]; other site
1006551008724	putative ATP binding site [chemical binding]; other site
1006551008725	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1006551008726	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1006551008727	Walker A/P-loop; other site
1006551008728	ATP binding site [chemical binding]; other site
1006551008729	Q-loop/lid; other site
1006551008730	ABC transporter signature motif; other site
1006551008731	Walker B; other site
1006551008732	D-loop; other site
1006551008733	H-loop/switch region; other site
1006551008734	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1006551008735	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1006551008736	ABC-ATPase subunit  interface; other site
1006551008737	dimer interface [polypeptide binding]; other site
1006551008738	putative PBP binding regions; other site
1006551008739	ferrichrome/ferrioxamine B periplasmic transporter; Provisional; Region: PRK14048
1006551008740	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1006551008741	intersubunit interface [polypeptide binding]; other site
1006551008742	Domain of unknown function (DUF3315); Region: DUF3315; pfam11776
1006551008743	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1006551008744	M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_like1; cd05666
1006551008745	metal binding site [ion binding]; metal-binding site
1006551008746	putative dimer interface [polypeptide binding]; other site
1006551008747	histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437
1006551008748	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551008749	substrate binding pocket [chemical binding]; other site
1006551008750	membrane-bound complex binding site; other site
1006551008751	hinge residues; other site
1006551008752	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1006551008753	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1006551008754	active site
1006551008755	catalytic tetrad [active]
1006551008756	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
1006551008757	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1006551008758	N-terminal plug; other site
1006551008759	ligand-binding site [chemical binding]; other site
1006551008760	phenylalanine transporter; Provisional; Region: PRK10249
1006551008761	Nucleoside H+ symporter; Region: Nuc_H_symport; pfam03825
1006551008762	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551008763	putative substrate translocation pore; other site
1006551008764	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1006551008765	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
1006551008766	Metal-binding active site; metal-binding site
1006551008767	AP endonuclease family 2 C terminus; Region: AP_endonuc_2_N; pfam07582
1006551008768	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1006551008769	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1006551008770	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1006551008771	short chain dehydrogenase; Provisional; Region: PRK06500
1006551008772	classical (c) SDRs; Region: SDR_c; cd05233
1006551008773	NAD(P) binding site [chemical binding]; other site
1006551008774	active site
1006551008775	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551008776	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551008777	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
1006551008778	putative effector binding pocket; other site
1006551008779	putative dimerization interface [polypeptide binding]; other site
1006551008780	helix_turn_helix, Lux Regulon; Region: HTH_LUXR; smart00421
1006551008781	DNA binding residues [nucleotide binding]
1006551008782	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1006551008783	fimbrial outer membrane usher protein TcfC; Provisional; Region: PRK15310
1006551008784	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1006551008785	putative fimbrial protein TcfA; Provisional; Region: PRK15308
1006551008786	Vi polysaccharide biosynthesis protein TviA; Provisional; Region: PRK15183
1006551008787	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
1006551008788	nudix motif; other site
1006551008789	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1006551008790	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1006551008791	DNA binding site [nucleotide binding]
1006551008792	domain linker motif; other site
1006551008793	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
1006551008794	dimerization interface [polypeptide binding]; other site
1006551008795	ligand binding site [chemical binding]; other site
1006551008796	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1006551008797	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1006551008798	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551008799	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1006551008800	putative substrate translocation pore; other site
1006551008801	Helix-turn-helix domain; Region: HTH_31; pfam13560
1006551008802	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
1006551008803	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1006551008804	Walker A motif; other site
1006551008805	ATP binding site [chemical binding]; other site
1006551008806	Walker B motif; other site
1006551008807	arginine finger; other site
1006551008808	Transcriptional antiterminator [Transcription]; Region: COG3933
1006551008809	PRD domain; Region: PRD; pfam00874
1006551008810	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1006551008811	active pocket/dimerization site; other site
1006551008812	active site
1006551008813	phosphorylation site [posttranslational modification]
1006551008814	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
1006551008815	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1006551008816	active pocket/dimerization site; other site
1006551008817	active site
1006551008818	phosphorylation site [posttranslational modification]
1006551008819	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1006551008820	active site
1006551008821	phosphorylation site [posttranslational modification]
1006551008822	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
1006551008823	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; cl01507
1006551008824	Glycosyl hydrolases family 32 N-terminal domain; Region: Glyco_hydro_32N; pfam00251
1006551008825	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
1006551008826	substrate binding [chemical binding]; other site
1006551008827	active site
1006551008828	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
1006551008829	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
1006551008830	type II secretion system protein C; Region: typeII_sec_gspC; TIGR01713
1006551008831	Type IV pilus biogenesis; Region: Pilus_PilP; pfam11356
1006551008832	type II secretion system protein D; Region: type_II_gspD; TIGR02517
1006551008833	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1006551008834	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1006551008835	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1006551008836	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1006551008837	type II secretion system protein E; Region: type_II_gspE; TIGR02533
1006551008838	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
1006551008839	Walker A motif; other site
1006551008840	ATP binding site [chemical binding]; other site
1006551008841	Walker B motif; other site
1006551008842	type II secretion system protein F; Region: GspF; TIGR02120
1006551008843	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1006551008844	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1006551008845	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
1006551008846	type II secretion system protein G; Region: typeII_sec_gspG; TIGR01710
1006551008847	Type II secretion system (T2SS), protein G; Region: T2SG; pfam08334
1006551008848	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
1006551008849	type II secretion system protein I; Region: gspI; TIGR01707
1006551008850	Type II secretion system (T2SS), protein I; Region: T2SI; pfam02501
1006551008851	type II secretion system protein J; Region: gspJ; TIGR01711
1006551008852	Type II secretion system (T2SS), protein J; Region: T2SJ; pfam11612
1006551008853	Type II secretion system (T2SS), protein K; Region: T2SK; pfam03934
1006551008854	Type II secretion system (T2SS), protein L; Region: T2SL; pfam05134
1006551008855	type II secretion system protein L; Region: typeII_sec_gspL; TIGR01709
1006551008856	GspL periplasmic domain; Region: GspL_C; pfam12693
1006551008857	Type II secretion system (T2SS), protein M; Region: T2SM; pfam04612
1006551008858	Type II secretion system (T2SS), protein N; Region: T2SN; pfam01203
1006551008859	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
1006551008860	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
1006551008861	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
1006551008862	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
1006551008863	dimer interface [polypeptide binding]; other site
1006551008864	FMN binding site [chemical binding]; other site
1006551008865	hypothetical protein; Provisional; Region: PRK10250
1006551008866	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1006551008867	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1006551008868	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1006551008869	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
1006551008870	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1006551008871	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551008872	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
1006551008873	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1006551008874	N-terminal plug; other site
1006551008875	ligand-binding site [chemical binding]; other site
1006551008876	enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439
1006551008877	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
1006551008878	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1006551008879	Protein of unknown function (DUF1158); Region: DUF1158; pfam06643
1006551008880	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
1006551008881	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
1006551008882	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1006551008883	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1006551008884	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1006551008885	motif II; other site
1006551008886	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1006551008887	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1006551008888	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1006551008889	HlyD family secretion protein; Region: HlyD_3; pfam13437
1006551008890	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1006551008891	Predicted periplasmic protein [Function unknown]; Region: COG3698
1006551008892	Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992
1006551008893	gamma-glutamyl:cysteine ligase; Provisional; Region: PRK13516
1006551008894	carboxylate-amine ligase, YbdK family; Region: gshA_cyan_rel; TIGR02050
1006551008895	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1006551008896	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_8; cd08495
1006551008897	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1006551008898	Protein of unknown function (DUF419); Region: DUF419; cl15265
1006551008899	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551008900	dimer interface [polypeptide binding]; other site
1006551008901	conserved gate region; other site
1006551008902	putative PBP binding loops; other site
1006551008903	ABC-ATPase subunit interface; other site
1006551008904	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1006551008905	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
1006551008906	dimer interface [polypeptide binding]; other site
1006551008907	ABC-ATPase subunit interface; other site
1006551008908	putative PBP binding loops; other site
1006551008909	ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; Region: AppF; COG4608
1006551008910	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1006551008911	Walker A/P-loop; other site
1006551008912	ATP binding site [chemical binding]; other site
1006551008913	Q-loop/lid; other site
1006551008914	ABC transporter signature motif; other site
1006551008915	Walker B; other site
1006551008916	D-loop; other site
1006551008917	H-loop/switch region; other site
1006551008918	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1006551008919	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1006551008920	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1006551008921	Walker A/P-loop; other site
1006551008922	ATP binding site [chemical binding]; other site
1006551008923	Q-loop/lid; other site
1006551008924	ABC transporter signature motif; other site
1006551008925	Walker B; other site
1006551008926	D-loop; other site
1006551008927	H-loop/switch region; other site
1006551008928	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1006551008929	Amidase; Region: Amidase; cl11426
1006551008930	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
1006551008931	allantoate amidohydrolase; Reviewed; Region: PRK12893
1006551008932	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
1006551008933	active site
1006551008934	metal binding site [ion binding]; metal-binding site
1006551008935	dimer interface [polypeptide binding]; other site
1006551008936	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
1006551008937	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1006551008938	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
1006551008939	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1006551008940	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551008941	DNA-binding site [nucleotide binding]; DNA binding site
1006551008942	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1006551008943	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551008944	homodimer interface [polypeptide binding]; other site
1006551008945	catalytic residue [active]
1006551008946	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1006551008947	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551008948	substrate binding pocket [chemical binding]; other site
1006551008949	membrane-bound complex binding site; other site
1006551008950	hinge residues; other site
1006551008951	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1006551008952	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551008953	dimer interface [polypeptide binding]; other site
1006551008954	conserved gate region; other site
1006551008955	putative PBP binding loops; other site
1006551008956	ABC-ATPase subunit interface; other site
1006551008957	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1006551008958	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551008959	dimer interface [polypeptide binding]; other site
1006551008960	conserved gate region; other site
1006551008961	putative PBP binding loops; other site
1006551008962	ABC-ATPase subunit interface; other site
1006551008963	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1006551008964	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1006551008965	Walker A/P-loop; other site
1006551008966	ATP binding site [chemical binding]; other site
1006551008967	Q-loop/lid; other site
1006551008968	ABC transporter signature motif; other site
1006551008969	Walker B; other site
1006551008970	D-loop; other site
1006551008971	H-loop/switch region; other site
1006551008972	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
1006551008973	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1006551008974	NAD(P) binding site [chemical binding]; other site
1006551008975	active site
1006551008976	hypothetical protein; Provisional; Region: PRK06062
1006551008977	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1006551008978	inhibitor-cofactor binding pocket; inhibition site
1006551008979	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551008980	catalytic residue [active]
1006551008981	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1006551008982	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1006551008983	Walker A/P-loop; other site
1006551008984	ATP binding site [chemical binding]; other site
1006551008985	Q-loop/lid; other site
1006551008986	ABC transporter signature motif; other site
1006551008987	Walker B; other site
1006551008988	D-loop; other site
1006551008989	H-loop/switch region; other site
1006551008990	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1006551008991	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1006551008992	Walker A/P-loop; other site
1006551008993	ATP binding site [chemical binding]; other site
1006551008994	Q-loop/lid; other site
1006551008995	ABC transporter signature motif; other site
1006551008996	Walker B; other site
1006551008997	D-loop; other site
1006551008998	H-loop/switch region; other site
1006551008999	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1006551009000	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551009001	dimer interface [polypeptide binding]; other site
1006551009002	conserved gate region; other site
1006551009003	ABC-ATPase subunit interface; other site
1006551009004	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1006551009005	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551009006	dimer interface [polypeptide binding]; other site
1006551009007	conserved gate region; other site
1006551009008	putative PBP binding loops; other site
1006551009009	ABC-ATPase subunit interface; other site
1006551009010	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1006551009011	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_7; cd08512
1006551009012	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1006551009013	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1006551009014	choline dehydrogenase; Validated; Region: PRK02106
1006551009015	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
1006551009016	betaine aldehyde dehydrogenase; Provisional; Region: PRK13252
1006551009017	NAD+-dependent 4-trimethylaminobutyraldehyde dehydrogenase, ALDH family 9A1; Region: ALDH_F9_TMBADH; cd07090
1006551009018	tetrameric interface [polypeptide binding]; other site
1006551009019	NAD binding site [chemical binding]; other site
1006551009020	catalytic residues [active]
1006551009021	transcriptional regulator BetI; Validated; Region: PRK00767
1006551009022	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1006551009023	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
1006551009024	choline transport protein BetT; Provisional; Region: PRK09928
1006551009025	Hok/gef family; Region: HOK_GEF; pfam01848
1006551009026	short chain dehydrogenase; Provisional; Region: PRK06114
1006551009027	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1006551009028	NAD(P) binding site [chemical binding]; other site
1006551009029	active site
1006551009030	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1006551009031	meso-2,3-butanediol dehydrogenase-like, classical (c) SDRs; Region: meso-BDH-like_SDR_c; cd05366
1006551009032	NAD binding site [chemical binding]; other site
1006551009033	homotetramer interface [polypeptide binding]; other site
1006551009034	homodimer interface [polypeptide binding]; other site
1006551009035	active site
1006551009036	substrate binding site [chemical binding]; other site
1006551009037	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1006551009038	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1006551009039	TM-ABC transporter signature motif; other site
1006551009040	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1006551009041	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1006551009042	Walker A/P-loop; other site
1006551009043	ATP binding site [chemical binding]; other site
1006551009044	Q-loop/lid; other site
1006551009045	ABC transporter signature motif; other site
1006551009046	Walker B; other site
1006551009047	D-loop; other site
1006551009048	H-loop/switch region; other site
1006551009049	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1006551009050	Predicted periplasmic lipoprotein (DUF2291); Region: DUF2291; cl02395
1006551009051	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1006551009052	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1006551009053	bacterial glycerol kinase 2-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_GK2_bacteria; cd07791
1006551009054	Glycerol kinase [Energy production and conversion]; Region: GlpK; COG0554
1006551009055	N- and C-terminal domain interface [polypeptide binding]; other site
1006551009056	active site
1006551009057	MgATP binding site [chemical binding]; other site
1006551009058	catalytic site [active]
1006551009059	metal binding site [ion binding]; metal-binding site
1006551009060	putative homotetramer interface [polypeptide binding]; other site
1006551009061	putative homodimer interface [polypeptide binding]; other site
1006551009062	glycerol binding site [chemical binding]; other site
1006551009063	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
1006551009064	MarR family; Region: MarR_2; cl17246
1006551009065	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
1006551009066	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1006551009067	TPP-binding site [chemical binding]; other site
1006551009068	dimer interface [polypeptide binding]; other site
1006551009069	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
1006551009070	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1006551009071	PYR/PP interface [polypeptide binding]; other site
1006551009072	dimer interface [polypeptide binding]; other site
1006551009073	TPP binding site [chemical binding]; other site
1006551009074	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1006551009075	phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex; Provisional; Region: PRK10251
1006551009076	outer membrane receptor FepA; Provisional; Region: PRK13524
1006551009077	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1006551009078	N-terminal plug; other site
1006551009079	ligand-binding site [chemical binding]; other site
1006551009080	enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439
1006551009081	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
1006551009082	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1006551009083	MbtH-like protein; Region: MbtH; cl01279
1006551009084	enterobactin synthase subunit F; Provisional; Region: entF; PRK10252
1006551009085	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1006551009086	acyl-activating enzyme (AAE) consensus motif; other site
1006551009087	AMP binding site [chemical binding]; other site
1006551009088	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1006551009089	iron-enterobactin transporter ATP-binding protein; Provisional; Region: PRK10253
1006551009090	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1006551009091	Walker A/P-loop; other site
1006551009092	ATP binding site [chemical binding]; other site
1006551009093	Q-loop/lid; other site
1006551009094	ABC transporter signature motif; other site
1006551009095	Walker B; other site
1006551009096	D-loop; other site
1006551009097	H-loop/switch region; other site
1006551009098	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
1006551009099	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1006551009100	ABC-ATPase subunit  interface; other site
1006551009101	dimer interface [polypeptide binding]; other site
1006551009102	putative PBP binding regions; other site
1006551009103	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1006551009104	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1006551009105	ABC-ATPase subunit  interface; other site
1006551009106	dimer interface [polypeptide binding]; other site
1006551009107	putative PBP binding regions; other site
1006551009108	enterobactin exporter EntS; Provisional; Region: PRK10489
1006551009109	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551009110	putative substrate translocation pore; other site
1006551009111	potential frameshift: common BLAST hit: gi|336248637|ref|YP_004592347.1| exochitinase
1006551009112	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
1006551009113	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
1006551009114	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
1006551009115	aromatic chitin/cellulose binding site residues [chemical binding]; other site
1006551009116	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
1006551009117	active site
1006551009118	iron-enterobactin transporter periplasmic binding protein; Provisional; Region: PRK10957
1006551009119	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
1006551009120	siderophore binding site; other site
1006551009121	isochorismate synthase EntC; Provisional; Region: PRK15016
1006551009122	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1006551009123	enterobactin synthase subunit E; Provisional; Region: entE; PRK10946
1006551009124	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
1006551009125	acyl-activating enzyme (AAE) consensus motif; other site
1006551009126	active site
1006551009127	AMP binding site [chemical binding]; other site
1006551009128	substrate binding site [chemical binding]; other site
1006551009129	Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase, catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of a vinyl ether, an uncommon reaction in biological...; Region: isochorismatase; cd01013
1006551009130	hydrophobic substrate binding pocket; other site
1006551009131	Isochorismatase family; Region: Isochorismatase; pfam00857
1006551009132	active site
1006551009133	conserved cis-peptide bond; other site
1006551009134	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
1006551009135	2,3-dihydroxybenzoate-2,3-dehydrogenase; Validated; Region: PRK08220
1006551009136	2,3 dihydro-2,3 dihydrozybenzoate dehydrogenases, classical (c) SDRs; Region: DH-DHB-DH_SDR_c; cd05331
1006551009137	putative NAD(P) binding site [chemical binding]; other site
1006551009138	active site
1006551009139	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1006551009140	CoenzymeA binding site [chemical binding]; other site
1006551009141	subunit interaction site [polypeptide binding]; other site
1006551009142	PHB binding site; other site
1006551009143	carbon starvation protein A; Provisional; Region: PRK15015
1006551009144	Carbon starvation protein CstA; Region: CstA; pfam02554
1006551009145	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1006551009146	Uncharacterized small protein [Function unknown]; Region: COG2879
1006551009147	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1006551009148	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1006551009149	salt bridge; other site
1006551009150	non-specific DNA binding site [nucleotide binding]; other site
1006551009151	sequence-specific DNA binding site [nucleotide binding]; other site
1006551009152	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
1006551009153	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1006551009154	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
1006551009155	putative active site [active]
1006551009156	metal binding site [ion binding]; metal-binding site
1006551009157	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1006551009158	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1006551009159	Walker A/P-loop; other site
1006551009160	ATP binding site [chemical binding]; other site
1006551009161	Q-loop/lid; other site
1006551009162	ABC transporter signature motif; other site
1006551009163	Walker B; other site
1006551009164	D-loop; other site
1006551009165	H-loop/switch region; other site
1006551009166	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1006551009167	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1006551009168	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1006551009169	TM-ABC transporter signature motif; other site
1006551009170	Methylthioribose-binding protein-like of ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_methylthioribose_binding_like; cd06305
1006551009171	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1006551009172	putative ligand binding site [chemical binding]; other site
1006551009173	Uncharacterized conserved protein [Function unknown]; Region: COG5276
1006551009174	methylthioribose kinase; Reviewed; Region: mtnK; PRK09550
1006551009175	Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family [Translation, ribosomal structure and biogenesis]; Region: COG0182; cl00348
1006551009176	methylthioribose-1-phosphate isomerase; Reviewed; Region: mtnA; PRK05720
1006551009177	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1006551009178	catalytic core [active]
1006551009179	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1006551009180	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
1006551009181	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551009182	putative substrate translocation pore; other site
1006551009183	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1006551009184	FIG, FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with various substrates. Fructose-1,6-bisphospatase (both the major and the glpX-encoded variant) hydrolyze fructose-1,6,-bisphosphate to fructose-6-phosphate in...; Region: FIG; cl00289
1006551009185	active site
1006551009186	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1006551009187	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1006551009188	DNA binding site [nucleotide binding]
1006551009189	domain linker motif; other site
1006551009190	Ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_LacI_like_2; cd06278
1006551009191	putative dimerization interface [polypeptide binding]; other site
1006551009192	putative ligand binding site [chemical binding]; other site
1006551009193	cytosine deaminase; Provisional; Region: PRK09230
1006551009194	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
1006551009195	active site
1006551009196	Purine catabolism regulatory protein-like family; Region: PucR; pfam07905
1006551009197	DRTGG domain; Region: DRTGG; pfam07085
1006551009198	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1006551009199	cytosine permease; Provisional; Region: codB; PRK11017
1006551009200	Na binding site [ion binding]; other site
1006551009201	methylthioribulose-1-phosphate dehydratase; Provisional; Region: PRK09220
1006551009202	intersubunit interface [polypeptide binding]; other site
1006551009203	active site
1006551009204	Zn2+ binding site [ion binding]; other site
1006551009205	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
1006551009206	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
1006551009207	putative N- and C-terminal domain interface [polypeptide binding]; other site
1006551009208	putative active site [active]
1006551009209	MgATP binding site [chemical binding]; other site
1006551009210	catalytic site [active]
1006551009211	metal binding site [ion binding]; metal-binding site
1006551009212	putative xylulose binding site [chemical binding]; other site
1006551009213	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
1006551009214	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_10; cd12171
1006551009215	putative ligand binding site [chemical binding]; other site
1006551009216	putative NAD binding site [chemical binding]; other site
1006551009217	catalytic site [active]
1006551009218	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1006551009219	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
1006551009220	substrate binding site [chemical binding]; other site
1006551009221	ATP binding site [chemical binding]; other site
1006551009222	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1006551009223	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1006551009224	TM-ABC transporter signature motif; other site
1006551009225	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1006551009226	TM-ABC transporter signature motif; other site
1006551009227	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1006551009228	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1006551009229	Walker A/P-loop; other site
1006551009230	ATP binding site [chemical binding]; other site
1006551009231	Q-loop/lid; other site
1006551009232	ABC transporter signature motif; other site
1006551009233	Walker B; other site
1006551009234	D-loop; other site
1006551009235	H-loop/switch region; other site
1006551009236	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1006551009237	Methylthioribose-binding protein-like of ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_methylthioribose_binding_like; cd06305
1006551009238	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1006551009239	putative ligand binding site [chemical binding]; other site
1006551009240	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
1006551009241	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
1006551009242	molybdopterin cofactor binding site [chemical binding]; other site
1006551009243	substrate binding site [chemical binding]; other site
1006551009244	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
1006551009245	molybdopterin cofactor binding site; other site
1006551009246	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1791
1006551009247	Cupin domain; Region: Cupin_2; cl17218
1006551009248	2,3-diketo-5-methylthio-1-phosphopentane phosphatase; Region: enolase-ppase; TIGR01691
1006551009249	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
1006551009250	motif II; other site
1006551009251	methionine aminotransferase; Validated; Region: PRK09082
1006551009252	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1006551009253	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551009254	homodimer interface [polypeptide binding]; other site
1006551009255	catalytic residue [active]
1006551009256	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
1006551009257	ParB-like nuclease domain; Region: ParBc; pfam02195
1006551009258	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
1006551009259	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1006551009260	Active Sites [active]
1006551009261	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
1006551009262	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551009263	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551009264	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
1006551009265	dimerization interface [polypeptide binding]; other site
1006551009266	alkyl hydroperoxide reductase subunit C; Provisional; Region: PRK10382
1006551009267	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1006551009268	dimer interface [polypeptide binding]; other site
1006551009269	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1006551009270	catalytic triad [active]
1006551009271	peroxidatic and resolving cysteines [active]
1006551009272	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
1006551009273	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
1006551009274	catalytic residue [active]
1006551009275	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
1006551009276	catalytic residues [active]
1006551009277	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1006551009278	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1006551009279	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1006551009280	Ligand Binding Site [chemical binding]; other site
1006551009281	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
1006551009282	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1006551009283	Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far.  This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases).  Plant T2 RNases are expressed during leaf...; Region: RNase_T2_prok; cd01062
1006551009284	B1 nucleotide binding pocket [chemical binding]; other site
1006551009285	B2 nucleotide binding pocket [chemical binding]; other site
1006551009286	CAS motifs; other site
1006551009287	active site
1006551009288	C4-dicarboxylate transporter DcuC; Provisional; Region: dcuC; PRK10654
1006551009289	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1006551009290	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
1006551009291	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1006551009292	DNA-binding site [nucleotide binding]; DNA binding site
1006551009293	RNA-binding motif; other site
1006551009294	chromosome condensation membrane protein; Provisional; Region: PRK14196
1006551009295	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1006551009296	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_3; cd07581
1006551009297	putative active site [active]
1006551009298	catalytic triad [active]
1006551009299	putative dimer interface [polypeptide binding]; other site
1006551009300	twin arginine translocase protein E; Validated; Region: tatE; PRK03625
1006551009301	lipoyl synthase; Provisional; Region: PRK05481
1006551009302	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1006551009303	FeS/SAM binding site; other site
1006551009304	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
1006551009305	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551009306	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
1006551009307	substrate binding pocket [chemical binding]; other site
1006551009308	dimerization interface [polypeptide binding]; other site
1006551009309	lipoate-protein ligase B; Provisional; Region: PRK14342
1006551009310	hypothetical protein; Provisional; Region: PRK04998
1006551009311	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
1006551009312	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1006551009313	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
1006551009314	rare lipoprotein A; Provisional; Region: PRK10672
1006551009315	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
1006551009316	Sporulation related domain; Region: SPOR; pfam05036
1006551009317	cell wall shape-determining protein; Provisional; Region: PRK10794
1006551009318	penicillin-binding protein 2; Provisional; Region: PRK10795
1006551009319	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1006551009320	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1006551009321	rRNA large subunit m3Psi methyltransferase RlmH; Region: tRNA_RlmH_YbeA; TIGR00246
1006551009322	ribosome-associated protein; Provisional; Region: PRK11538
1006551009323	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1006551009324	catalytic core [active]
1006551009325	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
1006551009326	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
1006551009327	active site
1006551009328	(T/H)XGH motif; other site
1006551009329	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
1006551009330	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
1006551009331	LPS-assembly lipoprotein RlpB; Provisional; Region: PRK10796
1006551009332	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
1006551009333	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1006551009334	HIGH motif; other site
1006551009335	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1006551009336	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1006551009337	active site
1006551009338	KMSKS motif; other site
1006551009339	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
1006551009340	tRNA binding surface [nucleotide binding]; other site
1006551009341	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1006551009342	hypothetical protein; Provisional; Region: PRK11032
1006551009343	SPX domain; Region: SPX; pfam03105
1006551009344	haemagglutination activity domain; Region: Haemagg_act; pfam05860
1006551009345	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
1006551009346	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
1006551009347	Haemolysin secretion/activation protein ShlB/FhaC/HecB; Region: ShlB; pfam03865
1006551009348	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1006551009349	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1006551009350	Walker A/P-loop; other site
1006551009351	ATP binding site [chemical binding]; other site
1006551009352	Q-loop/lid; other site
1006551009353	ABC transporter signature motif; other site
1006551009354	Walker B; other site
1006551009355	D-loop; other site
1006551009356	H-loop/switch region; other site
1006551009357	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551009358	dimer interface [polypeptide binding]; other site
1006551009359	conserved gate region; other site
1006551009360	putative PBP binding loops; other site
1006551009361	ABC-ATPase subunit interface; other site
1006551009362	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1006551009363	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551009364	dimer interface [polypeptide binding]; other site
1006551009365	conserved gate region; other site
1006551009366	putative PBP binding loops; other site
1006551009367	ABC-ATPase subunit interface; other site
1006551009368	glutamate and aspartate transporter subunit; Provisional; Region: PRK10797
1006551009369	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551009370	substrate binding pocket [chemical binding]; other site
1006551009371	membrane-bound complex binding site; other site
1006551009372	hinge residues; other site
1006551009373	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
1006551009374	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
1006551009375	putative active site [active]
1006551009376	catalytic triad [active]
1006551009377	putative dimer interface [polypeptide binding]; other site
1006551009378	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
1006551009379	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1006551009380	Transporter associated domain; Region: CorC_HlyC; smart01091
1006551009381	metal-binding heat shock protein; Provisional; Region: PRK00016
1006551009382	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1006551009383	PhoH-like protein; Region: PhoH; pfam02562
1006551009384	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
1006551009385	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1006551009386	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1006551009387	FeS/SAM binding site; other site
1006551009388	TRAM domain; Region: TRAM; pfam01938
1006551009389	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
1006551009390	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1006551009391	asparagine synthetase B; Provisional; Region: asnB; PRK09431
1006551009392	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
1006551009393	active site
1006551009394	dimer interface [polypeptide binding]; other site
1006551009395	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
1006551009396	Ligand Binding Site [chemical binding]; other site
1006551009397	Molecular Tunnel; other site
1006551009398	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1006551009399	UMP phosphatase; Provisional; Region: PRK10444
1006551009400	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1006551009401	active site
1006551009402	motif I; other site
1006551009403	motif II; other site
1006551009404	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1006551009405	MarR family; Region: MarR; pfam01047
1006551009406	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1006551009407	ROK family; Region: ROK; pfam00480
1006551009408	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
1006551009409	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
1006551009410	active site
1006551009411	dimer interface [polypeptide binding]; other site
1006551009412	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1006551009413	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1006551009414	active site
1006551009415	trimer interface [polypeptide binding]; other site
1006551009416	allosteric site; other site
1006551009417	active site lid [active]
1006551009418	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1006551009419	PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional; Region: PRK10255
1006551009420	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1006551009421	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1006551009422	active site turn [active]
1006551009423	phosphorylation site [posttranslational modification]
1006551009424	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1006551009425	HPr interaction site; other site
1006551009426	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1006551009427	active site
1006551009428	phosphorylation site [posttranslational modification]
1006551009429	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
1006551009430	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1006551009431	active site
1006551009432	HIGH motif; other site
1006551009433	nucleotide binding site [chemical binding]; other site
1006551009434	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
1006551009435	KMSKS motif; other site
1006551009436	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
1006551009437	outer membrane porin, OprD family; Region: OprD; pfam03573
1006551009438	YbfN-like lipoprotein; Region: YbfN; pfam13982
1006551009439	citrate-proton symporter; Provisional; Region: PRK15075
1006551009440	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551009441	putative substrate translocation pore; other site
1006551009442	tricarballylate utilization protein B; Provisional; Region: PRK15033
1006551009443	tricarballylate dehydrogenase; Validated; Region: PRK08274
1006551009444	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1006551009445	nitrogen assimilation transcriptional regulator; Provisional; Region: PRK11233
1006551009446	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551009447	The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433
1006551009448	putative dimerization interface [polypeptide binding]; other site
1006551009449	ferric uptake regulator; Provisional; Region: fur; PRK09462
1006551009450	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1006551009451	metal binding site 2 [ion binding]; metal-binding site
1006551009452	putative DNA binding helix; other site
1006551009453	metal binding site 1 [ion binding]; metal-binding site
1006551009454	dimer interface [polypeptide binding]; other site
1006551009455	structural Zn2+ binding site [ion binding]; other site
1006551009456	flavodoxin FldA; Validated; Region: PRK09267
1006551009457	LexA regulated protein; Provisional; Region: PRK11675
1006551009458	acyl-CoA esterase; Provisional; Region: PRK10673
1006551009459	PGAP1-like protein; Region: PGAP1; pfam07819
1006551009460	replication initiation regulator SeqA; Provisional; Region: PRK11187
1006551009461	phosphoglucomutase, alpha-D-glucose phosphate-specific; Region: pgm; TIGR01132
1006551009462	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
1006551009463	active site
1006551009464	substrate binding site [chemical binding]; other site
1006551009465	metal binding site [ion binding]; metal-binding site
1006551009466	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1006551009467	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1006551009468	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1006551009469	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1006551009470	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1006551009471	NAD(P) binding site [chemical binding]; other site
1006551009472	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
1006551009473	Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; Region: PBP1_ABC_sugar_binding_like_11; cd06321
1006551009474	putative ligand binding site [chemical binding]; other site
1006551009475	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1006551009476	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1006551009477	Walker A/P-loop; other site
1006551009478	ATP binding site [chemical binding]; other site
1006551009479	Q-loop/lid; other site
1006551009480	ABC transporter signature motif; other site
1006551009481	Walker B; other site
1006551009482	D-loop; other site
1006551009483	H-loop/switch region; other site
1006551009484	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1006551009485	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1006551009486	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1006551009487	TM-ABC transporter signature motif; other site
1006551009488	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
1006551009489	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
1006551009490	putative N- and C-terminal domain interface [polypeptide binding]; other site
1006551009491	putative active site [active]
1006551009492	MgATP binding site [chemical binding]; other site
1006551009493	catalytic site [active]
1006551009494	metal binding site [ion binding]; metal-binding site
1006551009495	putative xylulose binding site [chemical binding]; other site
1006551009496	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
1006551009497	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
1006551009498	AP (apurinic/apyrimidinic) site pocket; other site
1006551009499	DNA interaction; other site
1006551009500	Metal-binding active site; metal-binding site
1006551009501	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1006551009502	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1006551009503	intersubunit interface [polypeptide binding]; other site
1006551009504	active site
1006551009505	Zn2+ binding site [ion binding]; other site
1006551009506	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
1006551009507	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551009508	active site
1006551009509	phosphorylation site [posttranslational modification]
1006551009510	intermolecular recognition site; other site
1006551009511	dimerization interface [polypeptide binding]; other site
1006551009512	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1006551009513	DNA binding site [nucleotide binding]
1006551009514	sensor protein KdpD; Provisional; Region: PRK10490
1006551009515	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
1006551009516	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
1006551009517	Ligand Binding Site [chemical binding]; other site
1006551009518	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
1006551009519	GAF domain; Region: GAF_3; pfam13492
1006551009520	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1006551009521	dimer interface [polypeptide binding]; other site
1006551009522	phosphorylation site [posttranslational modification]
1006551009523	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551009524	ATP binding site [chemical binding]; other site
1006551009525	Mg2+ binding site [ion binding]; other site
1006551009526	G-X-G motif; other site
1006551009527	potassium-transporting ATPase subunit C; Reviewed; Region: PRK00315
1006551009528	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
1006551009529	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1006551009530	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
1006551009531	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
1006551009532	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
1006551009533	DNA photolyase; Region: DNA_photolyase; pfam00875
1006551009534	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1006551009535	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551009536	putative substrate translocation pore; other site
1006551009537	POT family; Region: PTR2; pfam00854
1006551009538	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1006551009539	metal-binding protein; Provisional; Region: PRK10799
1006551009540	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
1006551009541	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; cl00896
1006551009542	Allophanate hydrolase subunit 2 [Amino acid transport and metabolism]; Region: DUR1; COG1984
1006551009543	Escherichia coli putative lactam utilization protein YbgL and similar proteins; Region: LamB_YcsF_YbgL_like; cd10800
1006551009544	putative active site [active]
1006551009545	Protein of unknown function (DUF969); Region: DUF969; pfam06149
1006551009546	Predicted membrane protein [Function unknown]; Region: COG3817
1006551009547	Protein of unknown function (DUF979); Region: DUF979; pfam06166
1006551009548	Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I:  Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from...; Region: Peptidase_C15; cd00501
1006551009549	putative substrate binding pocket [chemical binding]; other site
1006551009550	AC domain interface; other site
1006551009551	catalytic triad [active]
1006551009552	AB domain interface; other site
1006551009553	interchain disulfide; other site
1006551009554	endonuclease VIII; Provisional; Region: PRK10445
1006551009555	N-terminal domain of Escherichia coli Nei/endonuclease VIII and related DNA glycosylases; Region: EcNei-like_N; cd08965
1006551009556	DNA binding site [nucleotide binding]
1006551009557	catalytic residue [active]
1006551009558	putative catalytic residues [active]
1006551009559	H2TH interface [polypeptide binding]; other site
1006551009560	intercalation triad [nucleotide binding]; other site
1006551009561	substrate specificity determining residue; other site
1006551009562	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1006551009563	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1006551009564	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
1006551009565	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
1006551009566	dimer interface [polypeptide binding]; other site
1006551009567	active site
1006551009568	citrylCoA binding site [chemical binding]; other site
1006551009569	NADH binding [chemical binding]; other site
1006551009570	cationic pore residues; other site
1006551009571	oxalacetate/citrate binding site [chemical binding]; other site
1006551009572	coenzyme A binding site [chemical binding]; other site
1006551009573	catalytic triad [active]
1006551009574	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
1006551009575	Iron-sulfur protein interface; other site
1006551009576	proximal quinone binding site [chemical binding]; other site
1006551009577	SdhD (CybS) interface [polypeptide binding]; other site
1006551009578	proximal heme binding site [chemical binding]; other site
1006551009579	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
1006551009580	SdhC subunit interface [polypeptide binding]; other site
1006551009581	proximal heme binding site [chemical binding]; other site
1006551009582	cardiolipin binding site; other site
1006551009583	Iron-sulfur protein interface; other site
1006551009584	proximal quinone binding site [chemical binding]; other site
1006551009585	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
1006551009586	L-aspartate oxidase; Provisional; Region: PRK06175
1006551009587	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1006551009588	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
1006551009589	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1006551009590	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
1006551009591	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
1006551009592	TPP-binding site [chemical binding]; other site
1006551009593	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
1006551009594	dimer interface [polypeptide binding]; other site
1006551009595	PYR/PP interface [polypeptide binding]; other site
1006551009596	TPP binding site [chemical binding]; other site
1006551009597	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
1006551009598	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1006551009599	E3 interaction surface; other site
1006551009600	lipoyl attachment site [posttranslational modification]; other site
1006551009601	e3 binding domain; Region: E3_binding; pfam02817
1006551009602	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1006551009603	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
1006551009604	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
1006551009605	CoA-ligase; Region: Ligase_CoA; pfam00549
1006551009606	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
1006551009607	CoA binding domain; Region: CoA_binding; smart00881
1006551009608	CoA-ligase; Region: Ligase_CoA; pfam00549
1006551009609	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1006551009610	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551009611	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1006551009612	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1006551009613	dimerization interface [polypeptide binding]; other site
1006551009614	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
1006551009615	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
1006551009616	homodimer interface [polypeptide binding]; other site
1006551009617	Walker A motif; other site
1006551009618	ATP binding site [chemical binding]; other site
1006551009619	hydroxycobalamin binding site [chemical binding]; other site
1006551009620	Walker B motif; other site
1006551009621	putative fumarate hydratase; Provisional; Region: PRK15392
1006551009622	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
1006551009623	Fumarase C-terminus; Region: Fumerase_C; pfam05683
1006551009624	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
1006551009625	Glutaminase; Region: Glutaminase; cl00907
1006551009626	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1006551009627	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
1006551009628	Domain of unknown function (DUF4387); Region: DUF4387; pfam14330
1006551009629	Protein of unknown function (DUF1446); Region: DUF1446; pfam07287
1006551009630	Methylaspartate ammonia-lyase [Amino acid transport and metabolism]; Region: Mal; COG3799
1006551009631	Methylaspartate ammonia lyase (3-methylaspartase, MAL) is a homodimeric enzyme, catalyzing the magnesium-dependent reversible alpha,beta-elimination of ammonia from L-threo-(2S,3S)-3-methylaspartic acid to mesaconic acid. This reaction is part of the...; Region: MAL; cd03314
1006551009632	dimer interface [polypeptide binding]; other site
1006551009633	active site
1006551009634	Coenzyme B12-dependent glutamate mutase epsilon subunit-like family; contains proteins similar to Clostridium cochlearium glutamate mutase (Glm) and Streptomyces tendae Tu901 NikV. Glm catalyzes a carbon-skeleton rearrangement of L-glutamate to...; Region: Glm_e; cd00245
1006551009635	substrate binding site [chemical binding]; other site
1006551009636	B12 cofactor binding site [chemical binding]; other site
1006551009637	heterodimer (sigma-epsilon) interface [polypeptide binding]; other site
1006551009638	homodimer (epsilon-epsilon) interface [polypeptide binding]; other site
1006551009639	conserved hypothetical protein; Region: glmL_fam; TIGR01319
1006551009640	B12 binding domain of glutamate mutase (Glm). Glutamate mutase catalysis the conversion of (S)-glutamate with (2S,3S)-3-methylaspartate. The rearrangement reaction is initiated by the extraction of a hydrogen from the protein-bound substrate by a 5'...; Region: Glm_B12_BD; cd02072
1006551009641	B12 binding site [chemical binding]; other site
1006551009642	heterodimer interface [polypeptide binding]; other site
1006551009643	cobalt ligand [ion binding]; other site
1006551009644	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
1006551009645	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
1006551009646	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003
1006551009647	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
1006551009648	Membrane bound YbgT-like protein; Region: YbgT_YccB; cl02039
1006551009649	hypothetical protein; Provisional; Region: PRK10588
1006551009650	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1006551009651	active site
1006551009652	colicin uptake protein TolQ; Provisional; Region: PRK10801
1006551009653	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1006551009654	colicin uptake protein TolR; Provisional; Region: PRK11024
1006551009655	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
1006551009656	TolA C-terminal; Region: TolA; pfam06519
1006551009657	translocation protein TolB; Provisional; Region: tolB; PRK03629
1006551009658	TolB amino-terminal domain; Region: TolB_N; pfam04052
1006551009659	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1006551009660	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1006551009661	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
1006551009662	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1006551009663	ligand binding site [chemical binding]; other site
1006551009664	tol-pal system protein YbgF; Provisional; Region: PRK10803
1006551009665	Tetratricopeptide repeat; Region: TPR_6; pfam13174
1006551009666	Tetratricopeptide repeat; Region: TPR_6; pfam13174
1006551009667	quinolinate synthetase; Provisional; Region: PRK09375
1006551009668	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
1006551009669	zinc transporter ZitB; Provisional; Region: PRK03557
1006551009670	YbgS-like protein; Region: YbgS; pfam13985
1006551009671	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
1006551009672	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1006551009673	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1006551009674	catalytic core [active]
1006551009675	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1006551009676	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
1006551009677	active site
1006551009678	catalytic residues [active]
1006551009679	galactokinase; Provisional; Region: PRK05101
1006551009680	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
1006551009681	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1006551009682	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1006551009683	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
1006551009684	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
1006551009685	dimer interface [polypeptide binding]; other site
1006551009686	active site
1006551009687	UDP-galactose-4-epimerase; Provisional; Region: PRK10675
1006551009688	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1006551009689	NAD binding site [chemical binding]; other site
1006551009690	homodimer interface [polypeptide binding]; other site
1006551009691	active site
1006551009692	substrate binding site [chemical binding]; other site
1006551009693	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
1006551009694	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
1006551009695	Walker A/P-loop; other site
1006551009696	ATP binding site [chemical binding]; other site
1006551009697	Q-loop/lid; other site
1006551009698	ABC transporter signature motif; other site
1006551009699	Walker B; other site
1006551009700	D-loop; other site
1006551009701	H-loop/switch region; other site
1006551009702	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551009703	Walker A/P-loop; other site
1006551009704	ATP binding site [chemical binding]; other site
1006551009705	Q-loop/lid; other site
1006551009706	ABC transporter signature motif; other site
1006551009707	Walker B; other site
1006551009708	D-loop; other site
1006551009709	H-loop/switch region; other site
1006551009710	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
1006551009711	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
1006551009712	TOBE domain; Region: TOBE; cl01440
1006551009713	TOBE domain; Region: TOBE; pfam03459
1006551009714	Protein of unknown function (DUF2592); Region: DUF2592; pfam10766
1006551009715	molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677
1006551009716	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551009717	substrate binding pocket [chemical binding]; other site
1006551009718	membrane-bound complex binding site; other site
1006551009719	hinge residues; other site
1006551009720	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1006551009721	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551009722	dimer interface [polypeptide binding]; other site
1006551009723	conserved gate region; other site
1006551009724	putative PBP binding loops; other site
1006551009725	ABC-ATPase subunit interface; other site
1006551009726	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
1006551009727	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551009728	Walker A/P-loop; other site
1006551009729	ATP binding site [chemical binding]; other site
1006551009730	Q-loop/lid; other site
1006551009731	ABC transporter signature motif; other site
1006551009732	Walker B; other site
1006551009733	D-loop; other site
1006551009734	H-loop/switch region; other site
1006551009735	molybdenum-pterin binding domain; Region: Mop; TIGR00638
1006551009736	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
1006551009737	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1006551009738	active site
1006551009739	motif I; other site
1006551009740	motif II; other site
1006551009741	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1006551009742	6-phosphogluconolactonase; Provisional; Region: PRK11028
1006551009743	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1006551009744	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1006551009745	Coenzyme A binding pocket [chemical binding]; other site
1006551009746	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1006551009747	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551009748	DNA-binding site [nucleotide binding]; DNA binding site
1006551009749	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1006551009750	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551009751	homodimer interface [polypeptide binding]; other site
1006551009752	catalytic residue [active]
1006551009753	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
1006551009754	Low iron-inducible periplasmic protein; Region: Fea1; pfam07692
1006551009755	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
1006551009756	Sensors of blue-light using FAD; Region: BLUF; smart01034
1006551009757	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1006551009758	transcriptional regulator MirA; Provisional; Region: PRK15043
1006551009759	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
1006551009760	DNA binding residues [nucleotide binding]
1006551009761	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1006551009762	helix_turn_helix, Lux Regulon; Region: HTH_LUXR; smart00421
1006551009763	DNA binding residues [nucleotide binding]
1006551009764	dimerization interface [polypeptide binding]; other site
1006551009765	acyl-CoA thioesterase; Provisional; Region: PRK10531
1006551009766	putative pectinesterase; Region: PLN02432; cl01911
1006551009767	imidazolonepropionase; Validated; Region: PRK09356
1006551009768	Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296
1006551009769	active site
1006551009770	histidine utilization repressor; Provisional; Region: PRK14999
1006551009771	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551009772	DNA-binding site [nucleotide binding]; DNA binding site
1006551009773	UTRA domain; Region: UTRA; pfam07702
1006551009774	urocanate hydratase; Provisional; Region: PRK05414
1006551009775	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
1006551009776	active sites [active]
1006551009777	tetramer interface [polypeptide binding]; other site
1006551009778	putative proline-specific permease; Provisional; Region: proY; PRK10580
1006551009779	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
1006551009780	substrate binding site [chemical binding]; other site
1006551009781	adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated; Region: PRK07986
1006551009782	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1006551009783	inhibitor-cofactor binding pocket; inhibition site
1006551009784	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551009785	catalytic residue [active]
1006551009786	biotin synthase; Provisional; Region: PRK15108
1006551009787	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1006551009788	FeS/SAM binding site; other site
1006551009789	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
1006551009790	8-amino-7-oxononanoate synthase; Reviewed; Region: PRK05958
1006551009791	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1006551009792	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1006551009793	catalytic residue [active]
1006551009794	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
1006551009795	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551009796	S-adenosylmethionine binding site [chemical binding]; other site
1006551009797	AAA domain; Region: AAA_26; pfam13500
1006551009798	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1006551009799	Dethiobiotin synthetase (DTBS) is the penultimate enzyme in the biotin biosynthesis pathway in Escherichia coli and other microorganisms. The enzyme catalyzes formation of the ureido ring of dethiobiotin from (7R,8S)-7,8-diaminononanoic acid (DAPA) and...; Region: DTBS; cd03109
1006551009800	urea ABC transporter, ATP-binding protein UrtE; Region: urea_trans_UrtE; TIGR03410
1006551009801	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
1006551009802	Walker A/P-loop; other site
1006551009803	ATP binding site [chemical binding]; other site
1006551009804	Q-loop/lid; other site
1006551009805	ABC transporter signature motif; other site
1006551009806	Walker B; other site
1006551009807	D-loop; other site
1006551009808	H-loop/switch region; other site
1006551009809	excinuclease ABC subunit B; Provisional; Region: PRK05298
1006551009810	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1006551009811	ATP binding site [chemical binding]; other site
1006551009812	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1006551009813	nucleotide binding region [chemical binding]; other site
1006551009814	ATP-binding site [chemical binding]; other site
1006551009815	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1006551009816	UvrB/uvrC motif; Region: UVR; pfam02151
1006551009817	sensor protein BasS/PmrB; Provisional; Region: PRK10755
1006551009818	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
1006551009819	dimer interface [polypeptide binding]; other site
1006551009820	phosphorylation site [posttranslational modification]
1006551009821	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551009822	ATP binding site [chemical binding]; other site
1006551009823	Mg2+ binding site [ion binding]; other site
1006551009824	G-X-G motif; other site
1006551009825	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
1006551009826	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551009827	active site
1006551009828	phosphorylation site [posttranslational modification]
1006551009829	intermolecular recognition site; other site
1006551009830	dimerization interface [polypeptide binding]; other site
1006551009831	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1006551009832	DNA binding site [nucleotide binding]
1006551009833	putative metal dependent hydrolase; Provisional; Region: PRK11598
1006551009834	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1006551009835	Sulfatase; Region: Sulfatase; pfam00884
1006551009836	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
1006551009837	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
1006551009838	phosphate binding site [ion binding]; other site
1006551009839	putative substrate binding pocket [chemical binding]; other site
1006551009840	dimer interface [polypeptide binding]; other site
1006551009841	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
1006551009842	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1006551009843	FeS/SAM binding site; other site
1006551009844	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
1006551009845	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1006551009846	MPT binding site; other site
1006551009847	trimer interface [polypeptide binding]; other site
1006551009848	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
1006551009849	trimer interface [polypeptide binding]; other site
1006551009850	dimer interface [polypeptide binding]; other site
1006551009851	putative active site [active]
1006551009852	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
1006551009853	MoaE interaction surface [polypeptide binding]; other site
1006551009854	MoeB interaction surface [polypeptide binding]; other site
1006551009855	thiocarboxylated glycine; other site
1006551009856	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
1006551009857	MoaE homodimer interface [polypeptide binding]; other site
1006551009858	MoaD interaction [polypeptide binding]; other site
1006551009859	active site residues [active]
1006551009860	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1006551009861	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1006551009862	Predicted integral membrane protein [Function unknown]; Region: COG0392
1006551009863	cardiolipin synthase 2; Provisional; Region: PRK11263
1006551009864	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
1006551009865	putative active site [active]
1006551009866	catalytic site [active]
1006551009867	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase ybhO and similar proteins; Region: PLDc_ybhO_like_2; cd09159
1006551009868	putative active site [active]
1006551009869	catalytic site [active]
1006551009870	Metal-dependent hydrolase [General function prediction only]; Region: ElsH; COG3568
1006551009871	putative catalytic site [active]
1006551009872	putative metal binding site [ion binding]; other site
1006551009873	putative phosphate binding site [ion binding]; other site
1006551009874	Putative inner membrane protein YbhQ; Region: YbhQ; pfam11076
1006551009875	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1006551009876	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1006551009877	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1006551009878	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
1006551009879	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1006551009880	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1006551009881	Walker A/P-loop; other site
1006551009882	ATP binding site [chemical binding]; other site
1006551009883	Q-loop/lid; other site
1006551009884	ABC transporter signature motif; other site
1006551009885	Walker B; other site
1006551009886	D-loop; other site
1006551009887	H-loop/switch region; other site
1006551009888	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
1006551009889	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1006551009890	Walker A/P-loop; other site
1006551009891	ATP binding site [chemical binding]; other site
1006551009892	Q-loop/lid; other site
1006551009893	ABC transporter signature motif; other site
1006551009894	Walker B; other site
1006551009895	D-loop; other site
1006551009896	H-loop/switch region; other site
1006551009897	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
1006551009898	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1006551009899	HlyD family secretion protein; Region: HlyD_3; pfam13437
1006551009900	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
1006551009901	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1006551009902	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
1006551009903	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1006551009904	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551009905	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1006551009906	dimerization interface [polypeptide binding]; other site
1006551009907	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551009908	D-galactonate transporter; Region: 2A0114; TIGR00893
1006551009909	putative substrate translocation pore; other site
1006551009910	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551009911	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1006551009912	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1006551009913	NAD(P) binding site [chemical binding]; other site
1006551009914	active site
1006551009915	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1006551009916	TPP-binding site [chemical binding]; other site
1006551009917	dimer interface [polypeptide binding]; other site
1006551009918	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
1006551009919	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1006551009920	PYR/PP interface [polypeptide binding]; other site
1006551009921	dimer interface [polypeptide binding]; other site
1006551009922	TPP binding site [chemical binding]; other site
1006551009923	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1006551009924	helicase 45; Provisional; Region: PTZ00424
1006551009925	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1006551009926	ATP binding site [chemical binding]; other site
1006551009927	Mg++ binding site [ion binding]; other site
1006551009928	motif III; other site
1006551009929	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1006551009930	nucleotide binding region [chemical binding]; other site
1006551009931	ATP-binding site [chemical binding]; other site
1006551009932	ATP-dependent DNA helicase DinG; Provisional; Region: dinG; PRK11747
1006551009933	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1006551009934	DEAD_2; Region: DEAD_2; pfam06733
1006551009935	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1006551009936	glycosyl transferase family protein; Provisional; Region: PRK08136
1006551009937	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1006551009938	Protein of unknown function (DUF1471); Region: DUF1471; cl11507
1006551009939	hypothetical protein; Provisional; Region: PRK11019
1006551009940	Fe(II)-dependent oxygenase superfamily protein; Provisional; Region: PRK05467
1006551009941	catecholate siderophore receptor Fiu; Provisional; Region: PRK09840
1006551009942	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1006551009943	N-terminal plug; other site
1006551009944	ligand-binding site [chemical binding]; other site
1006551009945	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
1006551009946	Protein of unknown function (DUF890); Region: Methyltransf_10; pfam05971
1006551009947	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551009948	S-adenosylmethionine binding site [chemical binding]; other site
1006551009949	putative mechanosensitive channel protein; Provisional; Region: PRK11465
1006551009950	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1006551009951	glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493
1006551009952	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1006551009953	Walker A/P-loop; other site
1006551009954	ATP binding site [chemical binding]; other site
1006551009955	Q-loop/lid; other site
1006551009956	ABC transporter signature motif; other site
1006551009957	Walker B; other site
1006551009958	D-loop; other site
1006551009959	H-loop/switch region; other site
1006551009960	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1006551009961	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551009962	dimer interface [polypeptide binding]; other site
1006551009963	conserved gate region; other site
1006551009964	putative PBP binding loops; other site
1006551009965	ABC-ATPase subunit interface; other site
1006551009966	glutamine ABC transporter periplasmic protein; Reviewed; Region: glnH; PRK09495
1006551009967	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551009968	substrate binding pocket [chemical binding]; other site
1006551009969	membrane-bound complex binding site; other site
1006551009970	hinge residues; other site
1006551009971	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
1006551009972	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
1006551009973	dimerization interface [polypeptide binding]; other site
1006551009974	DPS ferroxidase diiron center [ion binding]; other site
1006551009975	ion pore; other site
1006551009976	threonine and homoserine efflux system; Provisional; Region: PRK10532
1006551009977	EamA-like transporter family; Region: EamA; cl17759
1006551009978	outer membrane protein X; Provisional; Region: ompX; PRK09408
1006551009979	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
1006551009980	Sulfatase; Region: Sulfatase; pfam00884
1006551009981	manganese transport regulator MntR; Provisional; Region: PRK11050
1006551009982	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
1006551009983	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
1006551009984	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
1006551009985	transmembrane helices; other site
1006551009986	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1006551009987	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1006551009988	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1006551009989	active site
1006551009990	catalytic tetrad [active]
1006551009991	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1006551009992	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1006551009993	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551009994	DNA-binding site [nucleotide binding]; DNA binding site
1006551009995	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
1006551009996	L,D-transpeptidase; Provisional; Region: PRK10260
1006551009997	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1006551009998	Tyrosine phosphatase family; Region: Y_phosphatase3; pfam13350
1006551009999	Tyrosine phosphatase family C-terminal region; Region: Y_phosphatase3C; pfam13348
1006551010000	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
1006551010001	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1006551010002	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551010003	Walker A/P-loop; other site
1006551010004	ATP binding site [chemical binding]; other site
1006551010005	Q-loop/lid; other site
1006551010006	ABC transporter signature motif; other site
1006551010007	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1006551010008	Walker B; other site
1006551010009	D-loop; other site
1006551010010	ABC transporter; Region: ABC_tran_2; pfam12848
1006551010011	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1006551010012	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
1006551010013	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1006551010014	Glycosyl hydrolase family 31 (GH31) domain of a bacterial protein family represented by Escherichia coli protein Aec37. The gene encoding Aec37 (aec-37) is located within a genomic island (AGI-3) isolated from the extraintestinal avian pathogenic...; Region: GH31_glycosidase_Aec37; cd06599
1006551010015	putative active site [active]
1006551010016	putative catalytic site [active]
1006551010017	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551010018	D-galactonate transporter; Region: 2A0114; TIGR00893
1006551010019	putative substrate translocation pore; other site
1006551010020	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1006551010021	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1006551010022	DNA binding site [nucleotide binding]
1006551010023	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1006551010024	ligand binding site [chemical binding]; other site
1006551010025	dimerization interface [polypeptide binding]; other site
1006551010026	Protein of unknown function (DUF1479); Region: DUF1479; pfam07350
1006551010027	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
1006551010028	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1006551010029	active site
1006551010030	motif I; other site
1006551010031	motif II; other site
1006551010032	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1006551010033	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
1006551010034	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
1006551010035	dimer interface [polypeptide binding]; other site
1006551010036	active site
1006551010037	glycine loop; other site
1006551010038	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
1006551010039	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1006551010040	FeS/SAM binding site; other site
1006551010041	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
1006551010042	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1006551010043	ATP binding site [chemical binding]; other site
1006551010044	substrate interface [chemical binding]; other site
1006551010045	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
1006551010046	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
1006551010047	dimer interface [polypeptide binding]; other site
1006551010048	putative functional site; other site
1006551010049	putative MPT binding site; other site
1006551010050	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
1006551010051	catalytic nucleophile [active]
1006551010052	glutathione transporter ATP-binding protein; Provisional; Region: PRK10261
1006551010053	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1006551010054	Walker A/P-loop; other site
1006551010055	ATP binding site [chemical binding]; other site
1006551010056	Q-loop/lid; other site
1006551010057	ABC transporter signature motif; other site
1006551010058	Walker B; other site
1006551010059	D-loop; other site
1006551010060	H-loop/switch region; other site
1006551010061	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1006551010062	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1006551010063	Walker A/P-loop; other site
1006551010064	ATP binding site [chemical binding]; other site
1006551010065	Q-loop/lid; other site
1006551010066	ABC transporter signature motif; other site
1006551010067	Walker B; other site
1006551010068	D-loop; other site
1006551010069	H-loop/switch region; other site
1006551010070	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1006551010071	glutathione ABC transporter substrate-binding protein GsiB; Provisional; Region: PRK15413
1006551010072	The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499
1006551010073	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
1006551010074	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551010075	dimer interface [polypeptide binding]; other site
1006551010076	conserved gate region; other site
1006551010077	putative PBP binding loops; other site
1006551010078	ABC-ATPase subunit interface; other site
1006551010079	glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082
1006551010080	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1006551010081	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551010082	dimer interface [polypeptide binding]; other site
1006551010083	conserved gate region; other site
1006551010084	putative PBP binding loops; other site
1006551010085	ABC-ATPase subunit interface; other site
1006551010086	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
1006551010087	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1006551010088	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1006551010089	FeS/SAM binding site; other site
1006551010090	galactoside permease; Reviewed; Region: lacY; PRK09528
1006551010091	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551010092	putative substrate translocation pore; other site
1006551010093	biofilm formation regulatory protein BssR; Reviewed; Region: bssR; PRK12302
1006551010094	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
1006551010095	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
1006551010096	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1006551010097	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
1006551010098	putative C-terminal domain interface [polypeptide binding]; other site
1006551010099	putative GSH binding site (G-site) [chemical binding]; other site
1006551010100	putative dimer interface [polypeptide binding]; other site
1006551010101	C-terminal, alpha helical domain of an unknown subfamily 2 of Glutathione S-transferases; Region: GST_C_2; cd03180
1006551010102	putative N-terminal domain interface [polypeptide binding]; other site
1006551010103	putative dimer interface [polypeptide binding]; other site
1006551010104	putative substrate binding pocket (H-site) [chemical binding]; other site
1006551010105	Domain of unknown function (DUF3596); Region: DUF3596; pfam12167
1006551010106	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1006551010107	phiCTX phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various phage and bacterial integrases, including those similar to phage integrases: Bordetella and...; Region: INT_phiCTX_C; cd01191
1006551010108	Int/Topo IB signature motif; other site
1006551010109	Putative excisionase (DUF1233); Region: DUF1233; pfam06806
1006551010110	Methyltransferase domain; Region: Methyltransf_25; pfam13649
1006551010111	Protein of unknown function (DUF501); Region: DUF501; cl00652
1006551010112	Bacteriophage lambda Kil protein; Region: Lambda_Kil; pfam06301
1006551010113	transcriptional repressor DicA; Reviewed; Region: PRK09706
1006551010114	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1006551010115	non-specific DNA binding site [nucleotide binding]; other site
1006551010116	salt bridge; other site
1006551010117	sequence-specific DNA binding site [nucleotide binding]; other site
1006551010118	DNA-binding transcriptional regulator DicC; Provisional; Region: PRK09744
1006551010119	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
1006551010120	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220
1006551010121	PRTRC system ParB family protein; Region: PRTRC_parB; TIGR03734
1006551010122	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
1006551010123	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1006551010124	cofactor binding site; other site
1006551010125	DNA binding site [nucleotide binding]
1006551010126	substrate interaction site [chemical binding]; other site
1006551010127	DinI-like family; Region: DinI; cl11630
1006551010128	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
1006551010129	MT-A70; Region: MT-A70; cl01947
1006551010130	Antitermination protein; Region: Antiterm; pfam03589
1006551010131	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1006551010132	DnaJ central domain; Region: DnaJ_CXXCXGXG; pfam00684
1006551010133	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1006551010134	Protein of unknown function (DUF754); Region: DUF754; pfam05449
1006551010135	Predicted chitinase [General function prediction only]; Region: COG3179
1006551010136	catalytic residue [active]
1006551010137	Protein of unknown function (DUF2560); Region: DUF2560; cl10280
1006551010138	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
1006551010139	Protein of unknown function (DUF1441); Region: DUF1441; pfam07278
1006551010140	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
1006551010141	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
1006551010142	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
1006551010143	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_1; cd07016
1006551010144	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
1006551010145	oligomer interface [polypeptide binding]; other site
1006551010146	active site residues [active]
1006551010147	Uncharacterized conserved protein [Function unknown]; Region: COG5471
1006551010148	ATP-binding sugar transporter from pro-phage; Region: Gifsy-2; pfam13856
1006551010149	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
1006551010150	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
1006551010151	Bacteriophage lambda minor tail protein (GpG); Region: Phage_lambd_GpG; cl06106
1006551010152	Minor tail protein T; Region: Phage_tail_T; cl05636
1006551010153	Phage-related minor tail protein [Function unknown]; Region: COG5281
1006551010154	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
1006551010155	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
1006551010156	Domain of unknown function (DUF1833); Region: DUF1833; pfam08875
1006551010157	Putative phage tail protein; Region: Phage-tail_3; pfam13550
1006551010158	The S24, S26 LexA/signal peptidase superfamily contains LexA-related and type I signal peptidase families. The S24 LexA protein domains include: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the...; Region: Peptidase_S24_S26; cl10465
1006551010159	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
1006551010160	DNA binding site [nucleotide binding]
1006551010161	D-alanyl-D-alanine carboxypeptidase fraction C; Provisional; Region: PRK10001
1006551010162	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1006551010163	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
1006551010164	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
1006551010165	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1006551010166	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1006551010167	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
1006551010168	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1006551010169	active site
1006551010170	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
1006551010171	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551010172	putative substrate translocation pore; other site
1006551010173	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
1006551010174	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1006551010175	active site
1006551010176	motif I; other site
1006551010177	motif II; other site
1006551010178	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1006551010179	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551010180	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1006551010181	putative substrate translocation pore; other site
1006551010182	transcriptional repressor BetI; Region: betaine_BetI; TIGR03384
1006551010183	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1006551010184	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
1006551010185	Uncharacterized conserved protein [Function unknown]; Region: COG1479
1006551010186	Protein of unknown function DUF262; Region: DUF262; pfam03235
1006551010187	Uncharacterized conserved protein [Function unknown]; Region: COG3472
1006551010188	DNA-binding transcriptional regulator; Provisional; Region: PRK09678
1006551010189	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
1006551010190	putative transporter; Provisional; Region: PRK04972
1006551010191	Predicted Permease Membrane Region; Region: Asp-Al_Ex; cl06061
1006551010192	TrkA-C domain; Region: TrkA_C; pfam02080
1006551010193	TrkA-C domain; Region: TrkA_C; pfam02080
1006551010194	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
1006551010195	Predicted Permease Membrane Region; Region: Asp-Al_Ex; cl06061
1006551010196	Putative inner membrane protein of Enterobacteriaceae; Region: YbjM; pfam11045
1006551010197	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
1006551010198	GSH binding site [chemical binding]; other site
1006551010199	catalytic residues [active]
1006551010200	Protein of unknown function (DUF1418); Region: DUF1418; pfam07214
1006551010201	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
1006551010202	dimer interface [polypeptide binding]; other site
1006551010203	FMN binding site [chemical binding]; other site
1006551010204	NADPH bind site [chemical binding]; other site
1006551010205	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
1006551010206	RimK-like ATP-grasp domain; Region: RimK; pfam08443
1006551010207	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
1006551010208	putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682
1006551010209	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1006551010210	putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607
1006551010211	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551010212	Walker A/P-loop; other site
1006551010213	ATP binding site [chemical binding]; other site
1006551010214	Q-loop/lid; other site
1006551010215	ABC transporter signature motif; other site
1006551010216	Walker B; other site
1006551010217	D-loop; other site
1006551010218	H-loop/switch region; other site
1006551010219	TOBE domain; Region: TOBE_2; pfam08402
1006551010220	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551010221	dimer interface [polypeptide binding]; other site
1006551010222	conserved gate region; other site
1006551010223	putative PBP binding loops; other site
1006551010224	ABC-ATPase subunit interface; other site
1006551010225	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1006551010226	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551010227	dimer interface [polypeptide binding]; other site
1006551010228	conserved gate region; other site
1006551010229	putative PBP binding loops; other site
1006551010230	ABC-ATPase subunit interface; other site
1006551010231	Protein of unknown function (DUF2593); Region: DUF2593; pfam10767
1006551010232	23S rRNA (uracil-5-)-methyltransferase RumB; Region: meth_trns_rumB; TIGR02085
1006551010233	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551010234	S-adenosylmethionine binding site [chemical binding]; other site
1006551010235	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1006551010236	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551010237	active site
1006551010238	phosphorylation site [posttranslational modification]
1006551010239	intermolecular recognition site; other site
1006551010240	dimerization interface [polypeptide binding]; other site
1006551010241	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1006551010242	DNA binding site [nucleotide binding]
1006551010243	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
1006551010244	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1006551010245	dimer interface [polypeptide binding]; other site
1006551010246	phosphorylation site [posttranslational modification]
1006551010247	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551010248	ATP binding site [chemical binding]; other site
1006551010249	Mg2+ binding site [ion binding]; other site
1006551010250	G-X-G motif; other site
1006551010251	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
1006551010252	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551010253	substrate binding pocket [chemical binding]; other site
1006551010254	membrane-bound complex binding site; other site
1006551010255	hinge residues; other site
1006551010256	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1006551010257	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551010258	dimer interface [polypeptide binding]; other site
1006551010259	conserved gate region; other site
1006551010260	putative PBP binding loops; other site
1006551010261	ABC-ATPase subunit interface; other site
1006551010262	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1006551010263	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551010264	dimer interface [polypeptide binding]; other site
1006551010265	conserved gate region; other site
1006551010266	putative PBP binding loops; other site
1006551010267	ABC-ATPase subunit interface; other site
1006551010268	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
1006551010269	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551010270	substrate binding pocket [chemical binding]; other site
1006551010271	membrane-bound complex binding site; other site
1006551010272	hinge residues; other site
1006551010273	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
1006551010274	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551010275	Walker A/P-loop; other site
1006551010276	ATP binding site [chemical binding]; other site
1006551010277	Q-loop/lid; other site
1006551010278	ABC transporter signature motif; other site
1006551010279	Walker B; other site
1006551010280	D-loop; other site
1006551010281	H-loop/switch region; other site
1006551010282	putative lipoprotein; Provisional; Region: PRK10533
1006551010283	hypothetical protein; Provisional; Region: PRK02877
1006551010284	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1006551010285	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1006551010286	amidase catalytic site [active]
1006551010287	Zn binding residues [ion binding]; other site
1006551010288	substrate binding site [chemical binding]; other site
1006551010289	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1006551010290	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1006551010291	NAD(P) binding site [chemical binding]; other site
1006551010292	active site
1006551010293	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1006551010294	atypical (a) SDRs, subgroup 2; Region: SDR_a2; cd05245
1006551010295	putative NAD(P) binding site [chemical binding]; other site
1006551010296	putative active site [active]
1006551010297	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
1006551010298	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
1006551010299	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
1006551010300	tetramer interface [polypeptide binding]; other site
1006551010301	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551010302	catalytic residue [active]
1006551010303	pyruvate dehydrogenase; Provisional; Region: PRK09124
1006551010304	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
1006551010305	PYR/PP interface [polypeptide binding]; other site
1006551010306	dimer interface [polypeptide binding]; other site
1006551010307	tetramer interface [polypeptide binding]; other site
1006551010308	TPP binding site [chemical binding]; other site
1006551010309	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1006551010310	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
1006551010311	TPP-binding site [chemical binding]; other site
1006551010312	Predicted membrane protein [Function unknown]; Region: COG2259
1006551010313	HCP oxidoreductase, NADH-dependent; Provisional; Region: PRK10684
1006551010314	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215
1006551010315	FAD binding pocket [chemical binding]; other site
1006551010316	FAD binding motif [chemical binding]; other site
1006551010317	phosphate binding motif [ion binding]; other site
1006551010318	beta-alpha-beta structure motif; other site
1006551010319	NAD binding pocket [chemical binding]; other site
1006551010320	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1006551010321	catalytic loop [active]
1006551010322	iron binding site [ion binding]; other site
1006551010323	hybrid cluster protein; Provisional; Region: PRK05290
1006551010324	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1006551010325	ACS interaction site; other site
1006551010326	CODH interaction site; other site
1006551010327	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
1006551010328	hybrid metal cluster; other site
1006551010329	Predicted membrane protein [Function unknown]; Region: COG2431
1006551010330	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1006551010331	amphipathic channel; other site
1006551010332	Asn-Pro-Ala signature motifs; other site
1006551010333	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
1006551010334	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
1006551010335	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
1006551010336	putative active site [active]
1006551010337	putative metal-binding site [ion binding]; other site
1006551010338	macrolide transporter subunit MacA; Provisional; Region: PRK11578
1006551010339	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1006551010340	HlyD family secretion protein; Region: HlyD_3; pfam13437
1006551010341	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
1006551010342	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1006551010343	Walker A/P-loop; other site
1006551010344	ATP binding site [chemical binding]; other site
1006551010345	Q-loop/lid; other site
1006551010346	ABC transporter signature motif; other site
1006551010347	Walker B; other site
1006551010348	D-loop; other site
1006551010349	H-loop/switch region; other site
1006551010350	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1006551010351	FtsX-like permease family; Region: FtsX; pfam02687
1006551010352	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1006551010353	DNA-binding site [nucleotide binding]; DNA binding site
1006551010354	RNA-binding motif; other site
1006551010355	Uncharacterized conserved protein [Function unknown]; Region: COG2127
1006551010356	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
1006551010357	Clp amino terminal domain; Region: Clp_N; pfam02861
1006551010358	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1006551010359	Walker A motif; other site
1006551010360	ATP binding site [chemical binding]; other site
1006551010361	Walker B motif; other site
1006551010362	arginine finger; other site
1006551010363	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1006551010364	Walker A motif; other site
1006551010365	ATP binding site [chemical binding]; other site
1006551010366	Walker B motif; other site
1006551010367	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1006551010368	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-F; cd09718
1006551010369	CRISPR/Cas system-associated protein Cas3/Cas2; Region: Cas3_Cas2_I-F; cd09673
1006551010370	CRISPR-associated helicase Cas3, subtype I-F/YPEST; Region: cas3_yersinia; TIGR02562
1006551010371	CRISPR/Cas system-associated protein Csy1; Region: Csy1_I-F; cd09735
1006551010372	CRISPR/Cas system-associated RAMP superfamily protein Csy2; Region: Csy2_I-F; cd09736
1006551010373	CRISPR/Cas system-associated RAMP superfamily protein Csy3; Region: Csy3_I-F; cd09737
1006551010374	CRISPR/Cas system-associated RAMP superfamily protein Cas6f; Region: Cas6_I-F; cd09739
1006551010375	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1006551010376	rRNA binding site [nucleotide binding]; other site
1006551010377	predicted 30S ribosome binding site; other site
1006551010378	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
1006551010379	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
1006551010380	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551010381	Walker A/P-loop; other site
1006551010382	ATP binding site [chemical binding]; other site
1006551010383	Q-loop/lid; other site
1006551010384	ABC transporter signature motif; other site
1006551010385	Walker B; other site
1006551010386	D-loop; other site
1006551010387	H-loop/switch region; other site
1006551010388	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
1006551010389	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1006551010390	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551010391	Walker A/P-loop; other site
1006551010392	ATP binding site [chemical binding]; other site
1006551010393	Q-loop/lid; other site
1006551010394	ABC transporter signature motif; other site
1006551010395	Walker B; other site
1006551010396	D-loop; other site
1006551010397	H-loop/switch region; other site
1006551010398	thioredoxin reductase; Provisional; Region: PRK10262
1006551010399	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1006551010400	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1006551010401	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
1006551010402	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1006551010403	putative DNA binding site [nucleotide binding]; other site
1006551010404	putative Zn2+ binding site [ion binding]; other site
1006551010405	AsnC family; Region: AsnC_trans_reg; pfam01037
1006551010406	potential frameshift: common BLAST hit: gi|152969479|ref|YP_001334588.1| cell division protein
1006551010407	periplasmic chaperone LolA; Region: lolA; TIGR00547
1006551010408	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
1006551010409	recombination factor protein RarA; Reviewed; Region: PRK13342
1006551010410	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1006551010411	Walker A motif; other site
1006551010412	ATP binding site [chemical binding]; other site
1006551010413	Walker B motif; other site
1006551010414	arginine finger; other site
1006551010415	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
1006551010416	seryl-tRNA synthetase; Provisional; Region: PRK05431
1006551010417	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1006551010418	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1006551010419	dimer interface [polypeptide binding]; other site
1006551010420	active site
1006551010421	motif 1; other site
1006551010422	motif 2; other site
1006551010423	motif 3; other site
1006551010424	anaerobic dimethyl sulfoxide reductase subunit A; Provisional; Region: PRK14990
1006551010425	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1006551010426	putative [Fe4-S4] binding site [ion binding]; other site
1006551010427	putative molybdopterin cofactor binding site [chemical binding]; other site
1006551010428	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1006551010429	putative molybdopterin cofactor binding site; other site
1006551010430	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1006551010431	4Fe-4S binding domain; Region: Fer4; pfam00037
1006551010432	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
1006551010433	putative MFS family transporter protein; Provisional; Region: PRK03633
1006551010434	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551010435	putative substrate translocation pore; other site
1006551010436	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1006551010437	active site
1006551010438	phosphorylation site [posttranslational modification]
1006551010439	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
1006551010440	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1006551010441	PYR/PP interface [polypeptide binding]; other site
1006551010442	dimer interface [polypeptide binding]; other site
1006551010443	TPP binding site [chemical binding]; other site
1006551010444	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1006551010445	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1006551010446	TPP-binding site [chemical binding]; other site
1006551010447	dimer interface [polypeptide binding]; other site
1006551010448	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: PRK12997
1006551010449	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1006551010450	active site
1006551010451	P-loop; other site
1006551010452	phosphorylation site [posttranslational modification]
1006551010453	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1006551010454	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1006551010455	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1006551010456	putative active site [active]
1006551010457	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
1006551010458	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1006551010459	FeS/SAM binding site; other site
1006551010460	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
1006551010461	Pyruvate formate lyase 1; Region: PFL1; cd01678
1006551010462	coenzyme A binding site [chemical binding]; other site
1006551010463	active site
1006551010464	catalytic residues [active]
1006551010465	glycine loop; other site
1006551010466	formate transporter; Provisional; Region: PRK10805
1006551010467	uncharacterized domain; Region: TIGR00702
1006551010468	YcaO-like family; Region: YcaO; pfam02624
1006551010469	Predicted membrane protein [Function unknown]; Region: COG2323
1006551010470	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
1006551010471	homodimer interface [polypeptide binding]; other site
1006551010472	substrate-cofactor binding pocket; other site
1006551010473	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551010474	catalytic residue [active]
1006551010475	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
1006551010476	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
1006551010477	hinge; other site
1006551010478	active site
1006551010479	cytidylate kinase; Provisional; Region: cmk; PRK00023
1006551010480	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
1006551010481	CMP-binding site; other site
1006551010482	The sites determining sugar specificity; other site
1006551010483	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
1006551010484	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1006551010485	RNA binding site [nucleotide binding]; other site
1006551010486	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
1006551010487	RNA binding site [nucleotide binding]; other site
1006551010488	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
1006551010489	RNA binding site [nucleotide binding]; other site
1006551010490	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
1006551010491	RNA binding site [nucleotide binding]; other site
1006551010492	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
1006551010493	RNA binding site [nucleotide binding]; other site
1006551010494	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1006551010495	IHF dimer interface [polypeptide binding]; other site
1006551010496	IHF - DNA interface [nucleotide binding]; other site
1006551010497	Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658
1006551010498	Competence protein; Region: Competence; pfam03772
1006551010499	Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333
1006551010500	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1006551010501	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
1006551010502	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1006551010503	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1006551010504	Walker A/P-loop; other site
1006551010505	ATP binding site [chemical binding]; other site
1006551010506	Q-loop/lid; other site
1006551010507	ABC transporter signature motif; other site
1006551010508	Walker B; other site
1006551010509	D-loop; other site
1006551010510	H-loop/switch region; other site
1006551010511	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
1006551010512	tetraacyldisaccharide 4'-kinase; Region: lpxK; TIGR00682
1006551010513	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3214
1006551010514	Protein of unknown function (DUF1006); Region: DUF1006; pfam06224
1006551010515	Trm112p-like protein; Region: Trm112p; cl01066
1006551010516	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
1006551010517	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
1006551010518	Ligand binding site; other site
1006551010519	oligomer interface; other site
1006551010520	hypothetical protein; Provisional; Region: PRK10593
1006551010521	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1006551010522	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1006551010523	putative active site [active]
1006551010524	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1006551010525	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551010526	S-adenosylmethionine binding site [chemical binding]; other site
1006551010527	condesin subunit F; Provisional; Region: PRK05260
1006551010528	condesin subunit E; Provisional; Region: PRK05256
1006551010529	cell division protein MukB; Provisional; Region: mukB; PRK04863
1006551010530	P-loop containing region of AAA domain; Region: AAA_29; cl17516
1006551010531	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
1006551010532	murein L,D-transpeptidase; Provisional; Region: PRK10594
1006551010533	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1006551010534	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1006551010535	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1006551010536	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
1006551010537	Peptidase M15; Region: Peptidase_M15_3; cl01194
1006551010538	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1006551010539	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
1006551010540	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1006551010541	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551010542	homodimer interface [polypeptide binding]; other site
1006551010543	catalytic residue [active]
1006551010544	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1006551010545	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1006551010546	eyelet of channel; other site
1006551010547	trimer interface [polypeptide binding]; other site
1006551010548	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
1006551010549	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
1006551010550	putative dimer interface [polypeptide binding]; other site
1006551010551	putative anticodon binding site; other site
1006551010552	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
1006551010553	homodimer interface [polypeptide binding]; other site
1006551010554	motif 1; other site
1006551010555	motif 2; other site
1006551010556	active site
1006551010557	motif 3; other site
1006551010558	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
1006551010559	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
1006551010560	active site
1006551010561	aminopeptidase N; Provisional; Region: pepN; PRK14015
1006551010562	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
1006551010563	active site
1006551010564	Zn binding site [ion binding]; other site
1006551010565	aliphatic sulfonates transport ATP-binding subunit; Provisional; Region: ssuB; PRK11247
1006551010566	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1006551010567	Walker A/P-loop; other site
1006551010568	ATP binding site [chemical binding]; other site
1006551010569	Q-loop/lid; other site
1006551010570	ABC transporter signature motif; other site
1006551010571	Walker B; other site
1006551010572	D-loop; other site
1006551010573	H-loop/switch region; other site
1006551010574	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1006551010575	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551010576	dimer interface [polypeptide binding]; other site
1006551010577	conserved gate region; other site
1006551010578	putative PBP binding loops; other site
1006551010579	ABC-ATPase subunit interface; other site
1006551010580	NAD(P)H-dependent FMN reductase; Provisional; Region: PRK10569
1006551010581	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1006551010582	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
1006551010583	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
1006551010584	quinone interaction residues [chemical binding]; other site
1006551010585	active site
1006551010586	catalytic residues [active]
1006551010587	FMN binding site [chemical binding]; other site
1006551010588	substrate binding site [chemical binding]; other site
1006551010589	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
1006551010590	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
1006551010591	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
1006551010592	MOSC domain; Region: MOSC; pfam03473
1006551010593	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1006551010594	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1006551010595	catalytic loop [active]
1006551010596	iron binding site [ion binding]; other site
1006551010597	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
1006551010598	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
1006551010599	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551010600	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
1006551010601	putative RNA binding site [nucleotide binding]; other site
1006551010602	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551010603	S-adenosylmethionine binding site [chemical binding]; other site
1006551010604	ABC transporter ATPase component; Reviewed; Region: PRK11147
1006551010605	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551010606	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551010607	Walker A/P-loop; other site
1006551010608	Walker A/P-loop; other site
1006551010609	ATP binding site [chemical binding]; other site
1006551010610	ATP binding site [chemical binding]; other site
1006551010611	Q-loop/lid; other site
1006551010612	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1006551010613	ABC transporter signature motif; other site
1006551010614	Walker B; other site
1006551010615	D-loop; other site
1006551010616	ABC transporter; Region: ABC_tran_2; pfam12848
1006551010617	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1006551010618	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
1006551010619	Paraquat-inducible protein A; Region: PqiA; pfam04403
1006551010620	Paraquat-inducible protein A; Region: PqiA; pfam04403
1006551010621	paraquat-inducible protein B; Provisional; Region: PRK10807
1006551010622	mce related protein; Region: MCE; pfam02470
1006551010623	mce related protein; Region: MCE; pfam02470
1006551010624	mce related protein; Region: MCE; pfam02470
1006551010625	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
1006551010626	Protein of unknown function (DUF330); Region: DUF330; pfam03886
1006551010627	ribosome modulation factor; Provisional; Region: PRK14563
1006551010628	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
1006551010629	active site 1 [active]
1006551010630	dimer interface [polypeptide binding]; other site
1006551010631	active site 2 [active]
1006551010632	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
1006551010633	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1006551010634	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
1006551010635	outer membrane protein A; Reviewed; Region: PRK10808
1006551010636	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
1006551010637	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1006551010638	ligand binding site [chemical binding]; other site
1006551010639	cell division inhibitor SulA; Region: sula; TIGR00623
1006551010640	TfoX N-terminal domain; Region: TfoX_N; pfam04993
1006551010641	TfoX C-terminal domain; Region: TfoX_C; pfam04994
1006551010642	TIGR01666 family membrane protein; Region: YCCS
1006551010643	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
1006551010644	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1006551010645	Predicted membrane protein [Function unknown]; Region: COG3304
1006551010646	Domain of unknown function (DUF307); Region: DUF307; pfam03733
1006551010647	Domain of unknown function (DUF307); Region: DUF307; pfam03733
1006551010648	DNA helicase IV; Provisional; Region: helD; PRK11054
1006551010649	DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462
1006551010650	Part of AAA domain; Region: AAA_19; pfam13245
1006551010651	Family description; Region: UvrD_C_2; pfam13538
1006551010652	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
1006551010653	active site
1006551010654	dimer interfaces [polypeptide binding]; other site
1006551010655	catalytic residues [active]
1006551010656	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
1006551010657	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1006551010658	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1006551010659	Bacterial Ig-like domain (group 3); Region: Big_3_3; pfam13750
1006551010660	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1006551010661	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1006551010662	type I secretion C-terminal target domain (VC_A0849 subclass); Region: T1SS_VCA0849; TIGR03661
1006551010663	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
1006551010664	type I secretion system ATPase, LssB family; Region: type_I_sec_LssB; TIGR03375
1006551010665	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1006551010666	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551010667	Walker A/P-loop; other site
1006551010668	ATP binding site [chemical binding]; other site
1006551010669	Q-loop/lid; other site
1006551010670	ABC transporter signature motif; other site
1006551010671	Walker B; other site
1006551010672	D-loop; other site
1006551010673	H-loop/switch region; other site
1006551010674	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
1006551010675	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1006551010676	HlyD family secretion protein; Region: HlyD_3; pfam13437
1006551010677	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1006551010678	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1006551010679	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
1006551010680	heat shock protein HspQ; Provisional; Region: PRK14129
1006551010681	23S rRNA m(5)C1962 methyltransferase; Provisional; Region: PRK15128
1006551010682	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
1006551010683	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
1006551010684	putative RNA binding site [nucleotide binding]; other site
1006551010685	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551010686	S-adenosylmethionine binding site [chemical binding]; other site
1006551010687	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
1006551010688	substrate binding site [chemical binding]; other site
1006551010689	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1006551010690	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551010691	acylphosphatase; Provisional; Region: PRK14426
1006551010692	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
1006551010693	sulfur transfer protein TusE; Provisional; Region: PRK11508
1006551010694	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1006551010695	YccA-like proteins; Region: YccA_like; cd10433
1006551010696	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1006551010697	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1006551010698	peptide binding site [polypeptide binding]; other site
1006551010699	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1006551010700	outer membrane porin, OprD family; Region: OprD; pfam03573
1006551010701	hypothetical protein; Provisional; Region: PRK02947
1006551010702	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1006551010703	putative active site [active]
1006551010704	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
1006551010705	hypothetical protein; Provisional; Region: PRK02947
1006551010706	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1006551010707	putative active site [active]
1006551010708	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1006551010709	active site
1006551010710	phosphorylation site [posttranslational modification]
1006551010711	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
1006551010712	PTS system sorbose-specific iic component; Region: EII-Sor; pfam03609
1006551010713	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
1006551010714	active pocket/dimerization site; other site
1006551010715	active site
1006551010716	phosphorylation site [posttranslational modification]
1006551010717	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1006551010718	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551010719	DNA-binding site [nucleotide binding]; DNA binding site
1006551010720	UTRA domain; Region: UTRA; pfam07702
1006551010721	aspartate aminotransferase; Provisional; Region: PRK05764
1006551010722	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1006551010723	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551010724	homodimer interface [polypeptide binding]; other site
1006551010725	catalytic residue [active]
1006551010726	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
1006551010727	Glutamine amidotransferase class-I; Region: GATase; pfam00117
1006551010728	conserved cys residue [active]
1006551010729	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1006551010730	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
1006551010731	inhibitor site; inhibition site
1006551010732	active site
1006551010733	dimer interface [polypeptide binding]; other site
1006551010734	catalytic residue [active]
1006551010735	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
1006551010736	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1006551010737	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cd01066
1006551010738	active site
1006551010739	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
1006551010740	Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion; Region: enolase_like; cl17188
1006551010741	metal binding site [ion binding]; metal-binding site
1006551010742	substrate binding pocket [chemical binding]; other site
1006551010743	Peptidase M20 acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase (ArgE/DapE)-like; Region: M20_ArgE_DapE_like; cd08659
1006551010744	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK08651
1006551010745	metal binding site [ion binding]; metal-binding site
1006551010746	dimer interface [polypeptide binding]; other site
1006551010747	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1006551010748	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1006551010749	Walker A/P-loop; other site
1006551010750	ATP binding site [chemical binding]; other site
1006551010751	Q-loop/lid; other site
1006551010752	ABC transporter signature motif; other site
1006551010753	Walker B; other site
1006551010754	D-loop; other site
1006551010755	H-loop/switch region; other site
1006551010756	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551010757	dimer interface [polypeptide binding]; other site
1006551010758	conserved gate region; other site
1006551010759	putative PBP binding loops; other site
1006551010760	ABC-ATPase subunit interface; other site
1006551010761	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551010762	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1006551010763	substrate binding pocket [chemical binding]; other site
1006551010764	membrane-bound complex binding site; other site
1006551010765	hinge residues; other site
1006551010766	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551010767	DNA-binding site [nucleotide binding]; DNA binding site
1006551010768	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1006551010769	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1006551010770	FCD domain; Region: FCD; pfam07729
1006551010771	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1006551010772	putative beta-ketoacyl acyl carrier protein [ACP] reductase (BKR)-like, SDR; Region: BKR_like_SDR_like; cd05344
1006551010773	putative NAD(P) binding site [chemical binding]; other site
1006551010774	putative active site [active]
1006551010775	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551010776	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1006551010777	putative substrate translocation pore; other site
1006551010778	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551010779	tetracycline repressor protein TetR; Provisional; Region: PRK13756
1006551010780	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1006551010781	Tetracyclin repressor, C-terminal all-alpha domain; Region: TetR_C; pfam02909
1006551010782	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1006551010783	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551010784	alpha-galactosidase; Provisional; Region: PRK15076
1006551010785	Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases; Region: GH4_alpha_glucosidase_galactosidase; cd05297
1006551010786	NAD binding site [chemical binding]; other site
1006551010787	sugar binding site [chemical binding]; other site
1006551010788	divalent metal binding site [ion binding]; other site
1006551010789	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
1006551010790	dimer interface [polypeptide binding]; other site
1006551010791	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1006551010792	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551010793	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551010794	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1006551010795	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1006551010796	short chain dehydrogenase; Provisional; Region: PRK06179
1006551010797	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
1006551010798	NADP binding site [chemical binding]; other site
1006551010799	active site
1006551010800	steroid binding site; other site
1006551010801	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
1006551010802	alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases; Region: MDR_like_2; cd05289
1006551010803	putative NAD(P) binding site [chemical binding]; other site
1006551010804	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1006551010805	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1006551010806	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1006551010807	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1006551010808	HlyD family secretion protein; Region: HlyD_3; pfam13437
1006551010809	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1006551010810	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
1006551010811	hypothetical protein; Provisional; Region: PRK07505
1006551010812	7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism]; Region: BioF; COG0156
1006551010813	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1006551010814	catalytic residue [active]
1006551010815	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
1006551010816	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551010817	putative substrate translocation pore; other site
1006551010818	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1006551010819	EamA-like transporter family; Region: EamA; cl17759
1006551010820	EamA-like transporter family; Region: EamA; pfam00892
1006551010821	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1006551010822	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1006551010823	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1006551010824	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cl00224
1006551010825	homodimer interface [polypeptide binding]; other site
1006551010826	substrate-cofactor binding pocket; other site
1006551010827	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551010828	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1006551010829	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551010830	Walker A/P-loop; other site
1006551010831	ATP binding site [chemical binding]; other site
1006551010832	Q-loop/lid; other site
1006551010833	ABC transporter signature motif; other site
1006551010834	Walker B; other site
1006551010835	D-loop; other site
1006551010836	H-loop/switch region; other site
1006551010837	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1006551010838	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551010839	dimer interface [polypeptide binding]; other site
1006551010840	conserved gate region; other site
1006551010841	putative PBP binding loops; other site
1006551010842	ABC-ATPase subunit interface; other site
1006551010843	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551010844	dimer interface [polypeptide binding]; other site
1006551010845	conserved gate region; other site
1006551010846	ABC-ATPase subunit interface; other site
1006551010847	Uncharacterized protein involved in propionate catabolism [General function prediction only]; Region: PrpD; COG2079
1006551010848	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551010849	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1006551010850	substrate binding pocket [chemical binding]; other site
1006551010851	membrane-bound complex binding site; other site
1006551010852	hinge residues; other site
1006551010853	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551010854	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551010855	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
1006551010856	putative dimerization interface [polypeptide binding]; other site
1006551010857	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2828
1006551010858	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551010859	putative substrate translocation pore; other site
1006551010860	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1006551010861	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1006551010862	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1006551010863	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
1006551010864	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1006551010865	active site
1006551010866	nucleotide binding site [chemical binding]; other site
1006551010867	HIGH motif; other site
1006551010868	KMSKS motif; other site
1006551010869	citrate lyase subunit gamma; Provisional; Region: PRK13253
1006551010870	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
1006551010871	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
1006551010872	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase; Region: CitX; pfam03802
1006551010873	ATP:dephospho-CoA triphosphoribosyl transferase; Region: CitG; cl00768
1006551010874	Serine hydrolase; Region: Ser_hydrolase; pfam06821
1006551010875	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1006551010876	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
1006551010877	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
1006551010878	substrate binding site [chemical binding]; other site
1006551010879	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
1006551010880	substrate binding site [chemical binding]; other site
1006551010881	ligand binding site [chemical binding]; other site
1006551010882	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1006551010883	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1006551010884	transmembrane helices; other site
1006551010885	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1006551010886	DNA-binding site [nucleotide binding]; DNA binding site
1006551010887	RNA-binding motif; other site
1006551010888	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1006551010889	DNA-binding site [nucleotide binding]; DNA binding site
1006551010890	RNA-binding motif; other site
1006551010891	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
1006551010892	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1006551010893	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551010894	active site
1006551010895	phosphorylation site [posttranslational modification]
1006551010896	intermolecular recognition site; other site
1006551010897	dimerization interface [polypeptide binding]; other site
1006551010898	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1006551010899	DNA binding site [nucleotide binding]
1006551010900	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1006551010901	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1006551010902	dimerization interface [polypeptide binding]; other site
1006551010903	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1006551010904	dimer interface [polypeptide binding]; other site
1006551010905	phosphorylation site [posttranslational modification]
1006551010906	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551010907	ATP binding site [chemical binding]; other site
1006551010908	Mg2+ binding site [ion binding]; other site
1006551010909	G-X-G motif; other site
1006551010910	TupA-like ATPgrasp; Region: ATPgrasp_TupA; pfam14305
1006551010911	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1006551010912	homotrimer interaction site [polypeptide binding]; other site
1006551010913	putative active site [active]
1006551010914	probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858
1006551010915	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Energy production and conversion]; Region: COG2141
1006551010916	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
1006551010917	putative active site pocket [active]
1006551010918	dimerization interface [polypeptide binding]; other site
1006551010919	putative catalytic residue [active]
1006551010920	disulfide isomerase/thiol-disulfide oxidase; Provisional; Region: dsbG; PRK11657
1006551010921	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
1006551010922	dimerization domain [polypeptide binding]; other site
1006551010923	dimer interface [polypeptide binding]; other site
1006551010924	catalytic residues [active]
1006551010925	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
1006551010926	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1006551010927	catalytic residues [active]
1006551010928	Disulphide bond corrector protein DsbC; Region: DsbC; cl15830
1006551010929	Thiol:disulfide interchange protein [Posttranslational modification, protein turnover, chaperones / Energy production and conversion]; Region: COG4232
1006551010930	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
1006551010931	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
1006551010932	DsbD alpha interface [polypeptide binding]; other site
1006551010933	catalytic residues [active]
1006551010934	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
1006551010935	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551010936	The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466
1006551010937	putative substrate binding pocket [chemical binding]; other site
1006551010938	putative dimerization interface [polypeptide binding]; other site
1006551010939	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
1006551010940	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1006551010941	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
1006551010942	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551010943	dimer interface [polypeptide binding]; other site
1006551010944	conserved gate region; other site
1006551010945	ABC-ATPase subunit interface; other site
1006551010946	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551010947	dimer interface [polypeptide binding]; other site
1006551010948	conserved gate region; other site
1006551010949	putative PBP binding loops; other site
1006551010950	ABC-ATPase subunit interface; other site
1006551010951	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
1006551010952	ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259
1006551010953	Walker A/P-loop; other site
1006551010954	ATP binding site [chemical binding]; other site
1006551010955	Q-loop/lid; other site
1006551010956	ABC transporter signature motif; other site
1006551010957	Walker B; other site
1006551010958	D-loop; other site
1006551010959	H-loop/switch region; other site
1006551010960	TOBE domain; Region: TOBE_2; pfam08402
1006551010961	Phthalate dioxygenase reductase (PDR) is an FMN-dependent reductase that mediates electron transfer from NADH to FMN to an iron sulfur cluster. PDR has an an N-terminal  ferrredoxin reductase (FNR)-like NAD(H) binding domain and a C-terminal iron-sulfur; Region: PDR_like; cd06185
1006551010962	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018
1006551010963	FMN-binding pocket [chemical binding]; other site
1006551010964	flavin binding motif; other site
1006551010965	phosphate binding motif [ion binding]; other site
1006551010966	beta-alpha-beta structure motif; other site
1006551010967	NAD binding pocket [chemical binding]; other site
1006551010968	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1006551010969	catalytic loop [active]
1006551010970	iron binding site [ion binding]; other site
1006551010971	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
1006551010972	Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469
1006551010973	[2Fe-2S] cluster binding site [ion binding]; other site
1006551010974	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
1006551010975	hydrophobic ligand binding site; other site
1006551010976	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551010977	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551010978	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1006551010979	dimerization interface [polypeptide binding]; other site
1006551010980	FAD binding domain; Region: FAD_binding_3; pfam01494
1006551010981	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1006551010982	xanthine permease; Region: pbuX; TIGR03173
1006551010983	OHCU decarboxylase; Region: UraD_2; TIGR03180
1006551010984	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
1006551010985	active site
1006551010986	homotetramer interface [polypeptide binding]; other site
1006551010987	guanine deaminase; Provisional; Region: PRK09228
1006551010988	Guanine deaminase (GDEase). Guanine deaminase is an aminohydrolase responsible for the conversion of guanine to xanthine and ammonia, the first step to utilize guanine as a nitrogen source. This reaction also removes the guanine base from the pool and...; Region: GDEase; cd01303
1006551010989	active site
1006551010990	uncharacterized nucleobase-cation-symport-1 (NCS1) transporter subfamily; solute-binding domain; Region: SLC-NCS1sbd_u1; cd11555
1006551010991	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
1006551010992	Na binding site [ion binding]; other site
1006551010993	putative substrate binding site [chemical binding]; other site
1006551010994	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1006551010995	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551010996	DNA-binding site [nucleotide binding]; DNA binding site
1006551010997	FCD domain; Region: FCD; pfam07729
1006551010998	Hydantoin racemase [Amino acid transport and metabolism]; Region: COG4126
1006551010999	putative urate catabolism protein; Region: uraD_N-term-dom; TIGR03212
1006551011000	Catalytic domain of bacterial PuuE allantoinases, Schizosaccharomyces pombe chitin deacetylase 1 (SpCDA1), and similar proteins; Region: CE4_PuuE_SpCDA1; cd10977
1006551011001	active site
1006551011002	catalytic site [active]
1006551011003	tetramer interface [polypeptide binding]; other site
1006551011004	Protein of unknown function (DUF3225); Region: DUF3225; pfam11533
1006551011005	amidase; Provisional; Region: PRK09201
1006551011006	Amidase; Region: Amidase; pfam01425
1006551011007	Protein of unknown function (DUF4089); Region: DUF4089; pfam13318
1006551011008	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
1006551011009	Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019
1006551011010	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1006551011011	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1006551011012	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1006551011013	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551011014	substrate binding pocket [chemical binding]; other site
1006551011015	membrane-bound complex binding site; other site
1006551011016	hinge residues; other site
1006551011017	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1006551011018	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551011019	dimer interface [polypeptide binding]; other site
1006551011020	conserved gate region; other site
1006551011021	putative PBP binding loops; other site
1006551011022	ABC-ATPase subunit interface; other site
1006551011023	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
1006551011024	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551011025	ABC-ATPase subunit interface; other site
1006551011026	putative PBP binding loops; other site
1006551011027	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1006551011028	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1006551011029	Walker A/P-loop; other site
1006551011030	ATP binding site [chemical binding]; other site
1006551011031	Q-loop/lid; other site
1006551011032	ABC transporter signature motif; other site
1006551011033	Walker B; other site
1006551011034	D-loop; other site
1006551011035	H-loop/switch region; other site
1006551011036	Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075
1006551011037	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1006551011038	catalytic residue [active]
1006551011039	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
1006551011040	allantoate amidohydrolase; Reviewed; Region: PRK09290
1006551011041	active site
1006551011042	metal binding site [ion binding]; metal-binding site
1006551011043	dimer interface [polypeptide binding]; other site
1006551011044	Periplasmic pectate lyase; Region: Pectate_lyase_2; pfam06917
1006551011045	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; cl11629
1006551011046	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1006551011047	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1006551011048	DNA binding residues [nucleotide binding]
1006551011049	dimerization interface [polypeptide binding]; other site
1006551011050	Chorismate mutase type II; Region: CM_2; smart00830
1006551011051	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1006551011052	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1006551011053	metal binding site [ion binding]; metal-binding site
1006551011054	active site
1006551011055	I-site; other site
1006551011056	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1006551011057	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551011058	Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; cl17312
1006551011059	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1006551011060	active site
1006551011061	P-loop; other site
1006551011062	phosphorylation site [posttranslational modification]
1006551011063	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cl15377
1006551011064	FeS/SAM binding site; other site
1006551011065	pyruvate formate lyase II activase; Provisional; Region: PRK10076
1006551011066	putative formate acetyltransferase 2; Provisional; Region: pflD; PRK09983
1006551011067	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
1006551011068	dimer interface [polypeptide binding]; other site
1006551011069	active site
1006551011070	glycine loop; other site
1006551011071	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1006551011072	active site
1006551011073	P-loop; other site
1006551011074	phosphorylation site [posttranslational modification]
1006551011075	putative PTS system fructose-like transporter subunit EIIC; Provisional; Region: PRK10478
1006551011076	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1006551011077	dimerization domain swap beta strand [polypeptide binding]; other site
1006551011078	regulatory protein interface [polypeptide binding]; other site
1006551011079	active site
1006551011080	regulatory phosphorylation site [posttranslational modification]; other site
1006551011081	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1006551011082	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
1006551011083	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1006551011084	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1006551011085	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1006551011086	active site
1006551011087	phosphorylation site [posttranslational modification]
1006551011088	Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism]; Region: LeuB; COG0473
1006551011089	tartrate dehydrogenase; Region: TTC; TIGR02089
1006551011090	transcriptional activator TtdR; Provisional; Region: PRK09801
1006551011091	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551011092	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479
1006551011093	putative effector binding pocket; other site
1006551011094	putative dimerization interface [polypeptide binding]; other site
1006551011095	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
1006551011096	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1006551011097	gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK09847
1006551011098	Escherichia coli NADP+-dependent gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase PuuC-like; Region: ALDH_GABALDH-PuuC; cd07112
1006551011099	NAD(P) binding site [chemical binding]; other site
1006551011100	catalytic residues [active]
1006551011101	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
1006551011102	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1006551011103	non-specific DNA binding site [nucleotide binding]; other site
1006551011104	salt bridge; other site
1006551011105	sequence-specific DNA binding site [nucleotide binding]; other site
1006551011106	Cupin domain; Region: Cupin_2; pfam07883
1006551011107	gamma-glutamyl-gamma-aminobutyrate hydrolase; Provisional; Region: puuD; PRK11366
1006551011108	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
1006551011109	catalytic triad [active]
1006551011110	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
1006551011111	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1006551011112	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1006551011113	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
1006551011114	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1006551011115	catalytic core [active]
1006551011116	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1006551011117	hypothetical protein; Provisional; Region: PRK10174
1006551011118	NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767
1006551011119	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1006551011120	General stress protein [General function prediction only]; Region: GsiB; COG3729
1006551011121	pyrimidine utilization transport protein G; Region: RutG; TIGR03616
1006551011122	pyrimidine utilization flavin reductase protein F; Region: RutF; TIGR03615
1006551011123	Nitroreductase-like family 5.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_5; cd02148
1006551011124	putative FMN binding site [chemical binding]; other site
1006551011125	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1006551011126	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1006551011127	homotrimer interaction site [polypeptide binding]; other site
1006551011128	putative active site [active]
1006551011129	Isochorismatase family; Region: Isochorismatase; pfam00857
1006551011130	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1006551011131	catalytic triad [active]
1006551011132	conserved cis-peptide bond; other site
1006551011133	pyrimidine utilization protein A; Region: RutA; TIGR03612
1006551011134	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
1006551011135	active site
1006551011136	dimer interface [polypeptide binding]; other site
1006551011137	non-prolyl cis peptide bond; other site
1006551011138	insertion regions; other site
1006551011139	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1006551011140	HTH-type transcriptional regulator RutR; Provisional; Region: PRK15008
1006551011141	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1006551011142	YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362
1006551011143	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3755
1006551011144	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
1006551011145	Predicted transcriptional regulator [Transcription]; Region: COG3905
1006551011146	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
1006551011147	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
1006551011148	Glutamate binding site [chemical binding]; other site
1006551011149	NAD binding site [chemical binding]; other site
1006551011150	catalytic residues [active]
1006551011151	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1006551011152	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
1006551011153	Na binding site [ion binding]; other site
1006551011154	Protein of unknown function (DUF3574); Region: DUF3574; pfam12098
1006551011155	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1006551011156	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1006551011157	Nucleoside recognition; Region: Gate; pfam07670
1006551011158	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1006551011159	FTR1 family protein; Region: TIGR00145
1006551011160	inactive ferrous ion transporter periplasmic protein EfeO; Provisional; Region: PRK10378
1006551011161	Cupredoxin-like domain; Region: Cupredoxin_1; pfam13473
1006551011162	Imelysin; Region: Peptidase_M75; pfam09375
1006551011163	Tat-translocated enzyme; Region: tat_substr_1; TIGR01412
1006551011164	Predicted iron-dependent peroxidase [Inorganic ion transport and metabolism]; Region: COG2837
1006551011165	hypothetical protein; Provisional; Region: PRK10536
1006551011166	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1006551011167	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2350
1006551011168	MltA-interacting protein MipA; Region: MipA; cl01504
1006551011169	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1006551011170	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551011171	active site
1006551011172	phosphorylation site [posttranslational modification]
1006551011173	intermolecular recognition site; other site
1006551011174	dimerization interface [polypeptide binding]; other site
1006551011175	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1006551011176	DNA binding site [nucleotide binding]
1006551011177	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1006551011178	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1006551011179	dimer interface [polypeptide binding]; other site
1006551011180	phosphorylation site [posttranslational modification]
1006551011181	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551011182	ATP binding site [chemical binding]; other site
1006551011183	Mg2+ binding site [ion binding]; other site
1006551011184	G-X-G motif; other site
1006551011185	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1006551011186	HlyD family secretion protein; Region: HlyD_3; pfam13437
1006551011187	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1006551011188	Isochorismatase family; Region: Isochorismatase; pfam00857
1006551011189	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
1006551011190	catalytic triad [active]
1006551011191	dimer interface [polypeptide binding]; other site
1006551011192	conserved cis-peptide bond; other site
1006551011193	Pirin-related protein [General function prediction only]; Region: COG1741
1006551011194	Pirin; Region: Pirin; pfam02678
1006551011195	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
1006551011196	LysR family transcriptional regulator; Provisional; Region: PRK14997
1006551011197	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551011198	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_4; cd08473
1006551011199	putative effector binding pocket; other site
1006551011200	putative dimerization interface [polypeptide binding]; other site
1006551011201	bifunctional glyoxylate/hydroxypyruvate reductase A; Provisional; Region: ghrA; PRK15469
1006551011202	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164
1006551011203	putative ligand binding site [chemical binding]; other site
1006551011204	NAD binding site [chemical binding]; other site
1006551011205	dimerization interface [polypeptide binding]; other site
1006551011206	catalytic site [active]
1006551011207	putative hydrolase; Validated; Region: PRK09248
1006551011208	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
1006551011209	active site
1006551011210	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
1006551011211	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
1006551011212	Fimbrial protein; Region: Fimbrial; cl01416
1006551011213	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
1006551011214	putative ADP-ribose binding site [chemical binding]; other site
1006551011215	putative active site [active]
1006551011216	transcriptional repressor BetI; Region: betaine_BetI; TIGR03384
1006551011217	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1006551011218	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
1006551011219	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1006551011220	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
1006551011221	Periplasmic glucan biosynthesis protein, MdoG; Region: MdoG; pfam04349
1006551011222	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1006551011223	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
1006551011224	Ligand binding site; other site
1006551011225	DXD motif; other site
1006551011226	lipoprotein; Provisional; Region: PRK10175
1006551011227	secY/secA suppressor protein; Provisional; Region: PRK11467
1006551011228	drug efflux system protein MdtG; Provisional; Region: PRK09874
1006551011229	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551011230	putative substrate translocation pore; other site
1006551011231	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1006551011232	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1006551011233	putative acyl-acceptor binding pocket; other site
1006551011234	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
1006551011235	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
1006551011236	active site residue [active]
1006551011237	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
1006551011238	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1006551011239	biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301
1006551011240	DNA damage-inducible protein I; Provisional; Region: PRK10597
1006551011241	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
1006551011242	active site
1006551011243	substrate binding pocket [chemical binding]; other site
1006551011244	dimer interface [polypeptide binding]; other site
1006551011245	lipoprotein; Provisional; Region: PRK10598
1006551011246	glutaredoxin 2; Provisional; Region: PRK10387
1006551011247	GST_N family, Glutaredoxin 2 (GRX2) subfamily; composed of bacterial proteins similar to E. coli GRX2, an atypical GRX with a molecular mass of about 24kD, compared with other GRXs which are 9-12kD in size. GRX2 adopts a GST fold containing an N-terminal...; Region: GST_N_GRX2; cd03037
1006551011248	C-terminal domain interface [polypeptide binding]; other site
1006551011249	GSH binding site (G-site) [chemical binding]; other site
1006551011250	catalytic residues [active]
1006551011251	putative dimer interface [polypeptide binding]; other site
1006551011252	C-terminal, alpha helical domain of Glutaredoxin 2; Region: GST_C_GRX2; cd03199
1006551011253	N-terminal domain interface [polypeptide binding]; other site
1006551011254	multidrug resistance protein MdtH; Provisional; Region: PRK11646
1006551011255	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551011256	putative substrate translocation pore; other site
1006551011257	ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809
1006551011258	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1006551011259	hypothetical protein; Provisional; Region: PRK11239
1006551011260	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3132
1006551011261	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1006551011262	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1006551011263	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
1006551011264	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
1006551011265	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1006551011266	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551011267	putative substrate translocation pore; other site
1006551011268	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551011269	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551011270	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1006551011271	putative effector binding pocket; other site
1006551011272	dimerization interface [polypeptide binding]; other site
1006551011273	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
1006551011274	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1006551011275	homodimer interface [polypeptide binding]; other site
1006551011276	oligonucleotide binding site [chemical binding]; other site
1006551011277	Polyribonucleotide phosphorylase C terminal; Region: PNPase_C; pfam12111
1006551011278	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
1006551011279	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1006551011280	RNA binding surface [nucleotide binding]; other site
1006551011281	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1006551011282	active site
1006551011283	Abhydrolase family; Region: Abhydrolase_7; pfam12715
1006551011284	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1006551011285	Maf-like protein; Reviewed; Region: PRK00078
1006551011286	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1006551011287	active site
1006551011288	dimer interface [polypeptide binding]; other site
1006551011289	hypothetical protein; Provisional; Region: PRK11193
1006551011290	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
1006551011291	putative phosphate acyltransferase; Provisional; Region: PRK05331
1006551011292	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
1006551011293	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1006551011294	dimer interface [polypeptide binding]; other site
1006551011295	active site
1006551011296	CoA binding pocket [chemical binding]; other site
1006551011297	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1006551011298	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1006551011299	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1006551011300	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
1006551011301	NAD(P) binding site [chemical binding]; other site
1006551011302	homotetramer interface [polypeptide binding]; other site
1006551011303	homodimer interface [polypeptide binding]; other site
1006551011304	active site
1006551011305	acyl carrier protein; Provisional; Region: acpP; PRK00982
1006551011306	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
1006551011307	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1006551011308	dimer interface [polypeptide binding]; other site
1006551011309	active site
1006551011310	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1006551011311	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
1006551011312	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551011313	catalytic residue [active]
1006551011314	conserved hypothetical protein, YceG family; Region: TIGR00247
1006551011315	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
1006551011316	dimerization interface [polypeptide binding]; other site
1006551011317	thymidylate kinase; Validated; Region: tmk; PRK00698
1006551011318	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1006551011319	TMP-binding site; other site
1006551011320	ATP-binding site [chemical binding]; other site
1006551011321	DNA polymerase III subunit delta'; Validated; Region: PRK07993
1006551011322	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1006551011323	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
1006551011324	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1006551011325	active site
1006551011326	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
1006551011327	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1006551011328	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1006551011329	active site turn [active]
1006551011330	phosphorylation site [posttranslational modification]
1006551011331	ferric-rhodotorulic acid outer membrane transporter; Provisional; Region: PRK10003
1006551011332	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1006551011333	N-terminal plug; other site
1006551011334	ligand-binding site [chemical binding]; other site
1006551011335	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
1006551011336	nucleotide binding site/active site [active]
1006551011337	HIT family signature motif; other site
1006551011338	catalytic residue [active]
1006551011339	Predicted periplasmic lipoprotein [General function prediction only]; Region: COG5633
1006551011340	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
1006551011341	putative dimer interface [polypeptide binding]; other site
1006551011342	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
1006551011343	thiamine kinase; Region: ycfN_thiK; TIGR02721
1006551011344	active site
1006551011345	substrate binding site [chemical binding]; other site
1006551011346	ATP binding site [chemical binding]; other site
1006551011347	thiamine kinase; Provisional; Region: thiK; PRK10271
1006551011348	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1006551011349	beta-hexosaminidase; Provisional; Region: PRK05337
1006551011350	hypothetical protein; Provisional; Region: PRK04940
1006551011351	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
1006551011352	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1006551011353	hypothetical protein; Provisional; Region: PRK11280
1006551011354	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
1006551011355	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1006551011356	N-terminal plug; other site
1006551011357	ligand-binding site [chemical binding]; other site
1006551011358	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1006551011359	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1006551011360	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1006551011361	L,D-transpeptidase; Provisional; Region: PRK10190
1006551011362	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1006551011363	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1006551011364	transcription-repair coupling factor; Provisional; Region: PRK10689
1006551011365	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
1006551011366	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1006551011367	ATP binding site [chemical binding]; other site
1006551011368	putative Mg++ binding site [ion binding]; other site
1006551011369	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1006551011370	nucleotide binding region [chemical binding]; other site
1006551011371	ATP-binding site [chemical binding]; other site
1006551011372	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
1006551011373	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
1006551011374	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1006551011375	FtsX-like permease family; Region: FtsX; pfam02687
1006551011376	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
1006551011377	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1006551011378	Walker A/P-loop; other site
1006551011379	ATP binding site [chemical binding]; other site
1006551011380	Q-loop/lid; other site
1006551011381	ABC transporter signature motif; other site
1006551011382	Walker B; other site
1006551011383	D-loop; other site
1006551011384	H-loop/switch region; other site
1006551011385	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
1006551011386	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1006551011387	FtsX-like permease family; Region: FtsX; pfam02687
1006551011388	fructokinase; Reviewed; Region: PRK09557
1006551011389	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1006551011390	nucleotide binding site [chemical binding]; other site
1006551011391	NAD-dependent deacetylase; Provisional; Region: PRK00481
1006551011392	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
1006551011393	NAD+ binding site [chemical binding]; other site
1006551011394	substrate binding site [chemical binding]; other site
1006551011395	Zn binding site [ion binding]; other site
1006551011396	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
1006551011397	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1006551011398	DNA binding residues [nucleotide binding]
1006551011399	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
1006551011400	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1006551011401	substrate binding site [chemical binding]; other site
1006551011402	dimer interface [polypeptide binding]; other site
1006551011403	triosephosphate isomerase; Provisional; Region: PRK14565
1006551011404	catalytic triad [active]
1006551011405	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
1006551011406	Pyridoxal phosphate biosynthetic protein PdxA; Region: PdxA; cl00873
1006551011407	Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism]; Region: SrlE; COG3732
1006551011408	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
1006551011409	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
1006551011410	2-keto-3-deoxygluconate permease; Provisional; Region: PRK05274
1006551011411	PTS system glucitol/sorbitol-specific IIA component; Region: PTSIIA_gutA; pfam03829
1006551011412	ribose-5-phosphate isomerase B; Provisional; Region: PRK05571
1006551011413	transaldolase-like protein; Provisional; Region: PTZ00411
1006551011414	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
1006551011415	active site
1006551011416	dimer interface [polypeptide binding]; other site
1006551011417	catalytic residue [active]
1006551011418	transketolase; Reviewed; Region: PRK12753
1006551011419	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1006551011420	TPP-binding site [chemical binding]; other site
1006551011421	dimer interface [polypeptide binding]; other site
1006551011422	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1006551011423	PYR/PP interface [polypeptide binding]; other site
1006551011424	dimer interface [polypeptide binding]; other site
1006551011425	TPP binding site [chemical binding]; other site
1006551011426	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1006551011427	spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed; Region: potD; PRK09501
1006551011428	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
1006551011429	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1006551011430	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551011431	dimer interface [polypeptide binding]; other site
1006551011432	conserved gate region; other site
1006551011433	putative PBP binding loops; other site
1006551011434	ABC-ATPase subunit interface; other site
1006551011435	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1006551011436	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551011437	dimer interface [polypeptide binding]; other site
1006551011438	conserved gate region; other site
1006551011439	putative PBP binding loops; other site
1006551011440	ABC-ATPase subunit interface; other site
1006551011441	putrescine/spermidine ABC transporter ATPase protein; Reviewed; Region: potA; PRK09452
1006551011442	ATP-binding cassette domain of the polyamine transporter; Region: ABC_PotA_N; cd03300
1006551011443	Walker A/P-loop; other site
1006551011444	ATP binding site [chemical binding]; other site
1006551011445	Q-loop/lid; other site
1006551011446	ABC transporter signature motif; other site
1006551011447	Walker B; other site
1006551011448	D-loop; other site
1006551011449	H-loop/switch region; other site
1006551011450	TOBE domain; Region: TOBE_2; pfam08402
1006551011451	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
1006551011452	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
1006551011453	metal binding site [ion binding]; metal-binding site
1006551011454	dimer interface [polypeptide binding]; other site
1006551011455	Uncharacterized conserved protein [Function unknown]; Region: COG2850
1006551011456	sensor protein PhoQ; Provisional; Region: PRK10815
1006551011457	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
1006551011458	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
1006551011459	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551011460	ATP binding site [chemical binding]; other site
1006551011461	Mg2+ binding site [ion binding]; other site
1006551011462	G-X-G motif; other site
1006551011463	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
1006551011464	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551011465	active site
1006551011466	phosphorylation site [posttranslational modification]
1006551011467	intermolecular recognition site; other site
1006551011468	dimerization interface [polypeptide binding]; other site
1006551011469	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1006551011470	DNA binding site [nucleotide binding]
1006551011471	Predicted transcriptional regulators [Transcription]; Region: COG1733
1006551011472	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1006551011473	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1006551011474	adenylosuccinate lyase; Provisional; Region: PRK09285
1006551011475	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
1006551011476	tetramer interface [polypeptide binding]; other site
1006551011477	active site
1006551011478	putative lysogenization regulator; Reviewed; Region: PRK00218
1006551011479	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1006551011480	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
1006551011481	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
1006551011482	nudix motif; other site
1006551011483	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
1006551011484	Pseudouridine synthase, Escherichia coli RluE; Region: PseudoU_synth_RluE; cd02566
1006551011485	probable active site [active]
1006551011486	isocitrate dehydrogenase; Validated; Region: PRK07362
1006551011487	isocitrate dehydrogenase; Reviewed; Region: PRK07006
1006551011488	Bacteriophage lambda integrase, N-terminal domain; Region: Phage_integ_N; pfam09003
1006551011489	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1006551011490	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1006551011491	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
1006551011492	dimer interface [polypeptide binding]; other site
1006551011493	active site
1006551011494	Int/Topo IB signature motif; other site
1006551011495	Excisionase-like protein; Region: Exc; pfam07825
1006551011496	Enterobacterial exodeoxyribonuclease VIII; Region: Exonuc_VIII; pfam06630
1006551011497	exonuclease VIII; Reviewed; Region: PRK09709
1006551011498	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
1006551011499	active site
1006551011500	catalytic site [active]
1006551011501	substrate binding site [chemical binding]; other site
1006551011502	Predicted transcriptional regulator [Transcription]; Region: COG1959
1006551011503	Transcriptional regulator; Region: Rrf2; cl17282
1006551011504	KduI/IolB family; Region: KduI; cl01508
1006551011505	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
1006551011506	transcriptional repressor DicA; Reviewed; Region: PRK09706
1006551011507	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1006551011508	non-specific DNA binding site [nucleotide binding]; other site
1006551011509	salt bridge; other site
1006551011510	sequence-specific DNA binding site [nucleotide binding]; other site
1006551011511	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1006551011512	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1006551011513	non-specific DNA binding site [nucleotide binding]; other site
1006551011514	salt bridge; other site
1006551011515	sequence-specific DNA binding site [nucleotide binding]; other site
1006551011516	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
1006551011517	Pyocin large subunit [General function prediction only]; Region: COG5529
1006551011518	Helix-turn-helix domain; Region: HTH_36; pfam13730
1006551011519	primosomal protein DnaI; Provisional; Region: PRK02854
1006551011520	Replication protein P; Region: Phage_lambda_P; pfam06992
1006551011521	PerC transcriptional activator; Region: PerC; pfam06069
1006551011522	PTS_IIB: subunit IIB of enzyme II (EII) is the central energy-coupling domain of the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In the multienzyme PTS complex, EII is a carbohydrate-specific permease consisting of two cytoplasmic...; Region: PTS_IIB; cl10014
1006551011523	active site
1006551011524	P-loop; other site
1006551011525	phosphorylation site [posttranslational modification]
1006551011526	Uncharacterized conserved protein [Function unknown]; Region: COG3391
1006551011527	DinI-like family; Region: DinI; cl11630
1006551011528	Protein of unknown function (DUF968); Region: DUF968; pfam06147
1006551011529	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
1006551011530	Lysis protein S; Region: Lysis_S; pfam04971
1006551011531	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1006551011532	catalytic residues [active]
1006551011533	Protein of unknown function (DUF2514); Region: DUF2514; pfam10721
1006551011534	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
1006551011535	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1006551011536	active site
1006551011537	Phage terminase, small subunit; Region: Terminase_4; pfam05119
1006551011538	Phage terminase-like protein, large subunit [General function prediction only]; Region: COG4626
1006551011539	Phage portal protein; Region: Phage_portal; pfam04860
1006551011540	Phage-related protein [Function unknown]; Region: COG4695
1006551011541	Signal peptide peptidase A (SppA) 36K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_36K_type; cd07022
1006551011542	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
1006551011543	tandem repeat interface [polypeptide binding]; other site
1006551011544	oligomer interface [polypeptide binding]; other site
1006551011545	active site residues [active]
1006551011546	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
1006551011547	Phage capsid family; Region: Phage_capsid; pfam05065
1006551011548	Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; Region: gp6; cd08054
1006551011549	oligomerization interface [polypeptide binding]; other site
1006551011550	Bacteriophage protein of unknown function (DUF646); Region: DUF646; pfam04883
1006551011551	Phage tail protein; Region: Phage_tail_3; pfam08813
1006551011552	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
1006551011553	Phage minor tail protein; Region: Phage_min_tail; pfam05939
1006551011554	Phage minor tail protein L; Region: Phage_tail_L; cl01908
1006551011555	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
1006551011556	MPN+ (JAMM) motif; other site
1006551011557	Zinc-binding site [ion binding]; other site
1006551011558	NlpC/P60 family; Region: NLPC_P60; cl17555
1006551011559	Phage-related protein, tail component [Function unknown]; Region: COG4723
1006551011560	Phage-related protein, tail component [Function unknown]; Region: COG4733
1006551011561	Putative phage tail protein; Region: Phage-tail_3; pfam13550
1006551011562	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1006551011563	Interdomain contacts; other site
1006551011564	Cytokine receptor motif; other site
1006551011565	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
1006551011566	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
1006551011567	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
1006551011568	Fibronectin type III protein; Region: DUF3672; pfam12421
1006551011569	Chaperone of endosialidase; Region: Peptidase_S74; pfam13884
1006551011570	MASE2 domain; Region: MASE2; pfam05230
1006551011571	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1006551011572	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1006551011573	metal binding site [ion binding]; metal-binding site
1006551011574	active site
1006551011575	I-site; other site
1006551011576	EAL domain; Region: EAL; pfam00563
1006551011577	Isocitrate/isopropylmalate dehydrogenase; Region: Iso_dh; cl00445
1006551011578	HAMP domain; Region: HAMP; pfam00672
1006551011579	dimerization interface [polypeptide binding]; other site
1006551011580	GAF domain; Region: GAF; cl17456
1006551011581	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1006551011582	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1006551011583	metal binding site [ion binding]; metal-binding site
1006551011584	active site
1006551011585	I-site; other site
1006551011586	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1006551011587	Zn2+ binding site [ion binding]; other site
1006551011588	Mg2+ binding site [ion binding]; other site
1006551011589	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1006551011590	Zn2+ binding site [ion binding]; other site
1006551011591	Mg2+ binding site [ion binding]; other site
1006551011592	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
1006551011593	active site
1006551011594	homotetramer interface [polypeptide binding]; other site
1006551011595	homodimer interface [polypeptide binding]; other site
1006551011596	iron-dicitrate transporter ATP-binding subunit; Provisional; Region: fecE; PRK11231
1006551011597	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1006551011598	Walker A/P-loop; other site
1006551011599	ATP binding site [chemical binding]; other site
1006551011600	Q-loop/lid; other site
1006551011601	ABC transporter signature motif; other site
1006551011602	Walker B; other site
1006551011603	D-loop; other site
1006551011604	H-loop/switch region; other site
1006551011605	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1006551011606	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1006551011607	ABC-ATPase subunit  interface; other site
1006551011608	dimer interface [polypeptide binding]; other site
1006551011609	putative PBP binding regions; other site
1006551011610	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1006551011611	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1006551011612	ABC-ATPase subunit  interface; other site
1006551011613	dimer interface [polypeptide binding]; other site
1006551011614	putative PBP binding regions; other site
1006551011615	iron-dicitrate transporter substrate-binding subunit; Provisional; Region: fecB; PRK11411
1006551011616	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
1006551011617	siderophore binding site; other site
1006551011618	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
1006551011619	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1006551011620	N-terminal plug; other site
1006551011621	ligand-binding site [chemical binding]; other site
1006551011622	fec operon regulator FecR; Reviewed; Region: PRK09774
1006551011623	FecR protein; Region: FecR; pfam04773
1006551011624	RNA polymerase sigma factor FecI; Provisional; Region: PRK09651
1006551011625	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1006551011626	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1006551011627	DNA binding residues [nucleotide binding]
1006551011628	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1006551011629	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551011630	S-adenosylmethionine binding site [chemical binding]; other site
1006551011631	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1006551011632	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1006551011633	putative acyl-acceptor binding pocket; other site
1006551011634	leucine export protein LeuE; Provisional; Region: PRK10958
1006551011635	Protein of unknown function (DUF2534); Region: DUF2534; pfam10749
1006551011636	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1006551011637	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1006551011638	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1006551011639	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1006551011640	metal binding site [ion binding]; metal-binding site
1006551011641	active site
1006551011642	I-site; other site
1006551011643	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
1006551011644	Domain of unknown function (DUF333); Region: DUF333; pfam03891
1006551011645	Uncharacterized conserved protein [Function unknown]; Region: COG3189
1006551011646	Uncharacterized conserved protein [Function unknown]; Region: COG1683
1006551011647	hypothetical protein; Validated; Region: PRK06186
1006551011648	conserved cys residue [active]
1006551011649	Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807
1006551011650	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551011651	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1006551011652	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551011653	Predicted membrane protein [Function unknown]; Region: COG2707
1006551011654	YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function.  The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336
1006551011655	putative deacylase active site [active]
1006551011656	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1006551011657	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1006551011658	metal binding site [ion binding]; metal-binding site
1006551011659	active site
1006551011660	I-site; other site
1006551011661	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1006551011662	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1006551011663	hypothetical protein; Provisional; Region: PRK05325
1006551011664	PrkA family serine protein kinase; Provisional; Region: PRK15455
1006551011665	AAA ATPase domain; Region: AAA_16; pfam13191
1006551011666	Walker A motif; other site
1006551011667	ATP binding site [chemical binding]; other site
1006551011668	PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798
1006551011669	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
1006551011670	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1006551011671	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1006551011672	active site
1006551011673	catalytic tetrad [active]
1006551011674	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
1006551011675	active site
1006551011676	phosphate binding residues; other site
1006551011677	catalytic residues [active]
1006551011678	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
1006551011679	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1006551011680	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1006551011681	methionine sulfoxide reductase B; Provisional; Region: PRK00222
1006551011682	SelR domain; Region: SelR; pfam01641
1006551011683	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3139
1006551011684	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1006551011685	active site
1006551011686	The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an...; Region: GH18_chitinase; cd06548
1006551011687	Glyco_18 domain; Region: Glyco_18; smart00636
1006551011688	active site
1006551011689	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1006551011690	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH4; cd08258
1006551011691	putative NAD(P) binding site [chemical binding]; other site
1006551011692	catalytic Zn binding site [ion binding]; other site
1006551011693	structural Zn binding site [ion binding]; other site
1006551011694	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551011695	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551011696	Sorbitol dehydrogenase; Region: sorbitol_DH; cd05285
1006551011697	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1006551011698	inhibitor binding site; inhibition site
1006551011699	catalytic Zn binding site [ion binding]; other site
1006551011700	structural Zn binding site [ion binding]; other site
1006551011701	NADP binding site [chemical binding]; other site
1006551011702	tetramer interface [polypeptide binding]; other site
1006551011703	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1006551011704	intersubunit interface [polypeptide binding]; other site
1006551011705	active site
1006551011706	zinc binding site [ion binding]; other site
1006551011707	Na+ binding site [ion binding]; other site
1006551011708	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1006551011709	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1006551011710	substrate binding site [chemical binding]; other site
1006551011711	ATP binding site [chemical binding]; other site
1006551011712	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1006551011713	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1006551011714	active site
1006551011715	catalytic tetrad [active]
1006551011716	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1006551011717	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1006551011718	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1006551011719	benzoate transport; Region: 2A0115; TIGR00895
1006551011720	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551011721	putative substrate translocation pore; other site
1006551011722	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551011723	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
1006551011724	Isochorismatase family; Region: Isochorismatase; pfam00857
1006551011725	catalytic triad [active]
1006551011726	metal binding site [ion binding]; metal-binding site
1006551011727	conserved cis-peptide bond; other site
1006551011728	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
1006551011729	active site
1006551011730	homodimer interface [polypeptide binding]; other site
1006551011731	protease 4; Provisional; Region: PRK10949
1006551011732	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
1006551011733	tandem repeat interface [polypeptide binding]; other site
1006551011734	oligomer interface [polypeptide binding]; other site
1006551011735	active site residues [active]
1006551011736	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_1; cd07019
1006551011737	tandem repeat interface [polypeptide binding]; other site
1006551011738	oligomer interface [polypeptide binding]; other site
1006551011739	active site residues [active]
1006551011740	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
1006551011741	putative FMN binding site [chemical binding]; other site
1006551011742	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
1006551011743	active site
1006551011744	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1006551011745	selenophosphate synthetase; Provisional; Region: PRK00943
1006551011746	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
1006551011747	dimerization interface [polypeptide binding]; other site
1006551011748	putative ATP binding site [chemical binding]; other site
1006551011749	DNA topoisomerase III; Provisional; Region: PRK07726
1006551011750	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
1006551011751	active site
1006551011752	putative interdomain interaction site [polypeptide binding]; other site
1006551011753	putative metal-binding site [ion binding]; other site
1006551011754	putative nucleotide binding site [chemical binding]; other site
1006551011755	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1006551011756	domain I; other site
1006551011757	DNA binding groove [nucleotide binding]
1006551011758	phosphate binding site [ion binding]; other site
1006551011759	domain II; other site
1006551011760	domain III; other site
1006551011761	nucleotide binding site [chemical binding]; other site
1006551011762	catalytic site [active]
1006551011763	domain IV; other site
1006551011764	glutamate dehydrogenase; Provisional; Region: PRK09414
1006551011765	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1006551011766	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
1006551011767	NAD(P) binding site [chemical binding]; other site
1006551011768	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
1006551011769	active site
1006551011770	8-oxo-dGMP binding site [chemical binding]; other site
1006551011771	nudix motif; other site
1006551011772	metal binding site [ion binding]; metal-binding site
1006551011773	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
1006551011774	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
1006551011775	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
1006551011776	active site residue [active]
1006551011777	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
1006551011778	active site residue [active]
1006551011779	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4136
1006551011780	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551011781	Walker A/P-loop; other site
1006551011782	ATP binding site [chemical binding]; other site
1006551011783	Q-loop/lid; other site
1006551011784	ABC transporter signature motif; other site
1006551011785	Walker B; other site
1006551011786	D-loop; other site
1006551011787	H-loop/switch region; other site
1006551011788	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4135
1006551011789	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4134
1006551011790	hypothetical protein; Provisional; Region: PRK11622
1006551011791	Uncharacterized conserved protein [Function unknown]; Region: COG2128
1006551011792	Carboxymuconolactone decarboxylase family; Region: CMD; cl00460
1006551011793	Uncharacterized conserved protein [Function unknown]; Region: COG0398
1006551011794	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1006551011795	Uncharacterized conserved protein [Function unknown]; Region: COG0398
1006551011796	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1006551011797	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
1006551011798	putative catalytic site [active]
1006551011799	putative phosphate binding site [ion binding]; other site
1006551011800	active site
1006551011801	metal binding site A [ion binding]; metal-binding site
1006551011802	DNA binding site [nucleotide binding]
1006551011803	putative AP binding site [nucleotide binding]; other site
1006551011804	putative metal binding site B [ion binding]; other site
1006551011805	bifunctional succinylornithine transaminase/acetylornithine transaminase; Provisional; Region: PRK12381
1006551011806	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1006551011807	inhibitor-cofactor binding pocket; inhibition site
1006551011808	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551011809	catalytic residue [active]
1006551011810	arginine succinyltransferase; Provisional; Region: PRK10456
1006551011811	Arginine/ornithine N-succinyltransferase beta subunit [Amino acid transport and metabolism]; Region: AstA; COG3138
1006551011812	succinylglutamic semialdehyde dehydrogenase; Reviewed; Region: astD; PRK09457
1006551011813	N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095
1006551011814	NAD(P) binding site [chemical binding]; other site
1006551011815	catalytic residues [active]
1006551011816	succinylarginine dihydrolase; Provisional; Region: PRK13281
1006551011817	Peptidase M14 Succinylglutamate desuccinylase (ASTE) subfamily; Region: M14_ASTE; cd03855
1006551011818	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
1006551011819	putative active site [active]
1006551011820	Zn binding site [ion binding]; other site
1006551011821	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1006551011822	dimer interface [polypeptide binding]; other site
1006551011823	Uncharacterized conserved protein [Function unknown]; Region: LemA; COG1704
1006551011824	Predicted membrane protein (DUF2207); Region: DUF2207; pfam09972
1006551011825	nucleotide excision repair endonuclease; Provisional; Region: PRK10545
1006551011826	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1006551011827	GIY-YIG motif/motif A; other site
1006551011828	active site
1006551011829	catalytic site [active]
1006551011830	putative DNA binding site [nucleotide binding]; other site
1006551011831	metal binding site [ion binding]; metal-binding site
1006551011832	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
1006551011833	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
1006551011834	homodimer interface [polypeptide binding]; other site
1006551011835	NAD binding pocket [chemical binding]; other site
1006551011836	ATP binding pocket [chemical binding]; other site
1006551011837	Mg binding site [ion binding]; other site
1006551011838	active-site loop [active]
1006551011839	DNA-binding transcriptional activator OsmE; Provisional; Region: PRK11251
1006551011840	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1006551011841	active site
1006551011842	P-loop; other site
1006551011843	phosphorylation site [posttranslational modification]
1006551011844	PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC; Provisional; Region: PRK10297
1006551011845	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1006551011846	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1006551011847	methionine cluster; other site
1006551011848	active site
1006551011849	phosphorylation site [posttranslational modification]
1006551011850	metal binding site [ion binding]; metal-binding site
1006551011851	DNA-binding transcriptional regulator ChbR; Provisional; Region: PRK10296
1006551011852	Cupin domain; Region: Cupin_2; pfam07883
1006551011853	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551011854	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
1006551011855	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
1006551011856	NAD binding site [chemical binding]; other site
1006551011857	sugar binding site [chemical binding]; other site
1006551011858	divalent metal binding site [ion binding]; other site
1006551011859	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1006551011860	dimer interface [polypeptide binding]; other site
1006551011861	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
1006551011862	putative active site [active]
1006551011863	YdjC motif; other site
1006551011864	Mg binding site [ion binding]; other site
1006551011865	putative homodimer interface [polypeptide binding]; other site
1006551011866	hydroperoxidase II; Provisional; Region: katE; PRK11249
1006551011867	Clade 2 of the heme-binding enzyme catalase; Region: catalase_clade_2; cd08155
1006551011868	tetramer interface [polypeptide binding]; other site
1006551011869	heme binding pocket [chemical binding]; other site
1006551011870	Type 1 glutamine amidotransferase (GATase1)-like domain found in at the C-terminal of several large catalases; Region: GATase1_catalase; cd03132
1006551011871	domain interactions; other site
1006551011872	cell division modulator; Provisional; Region: PRK10113
1006551011873	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
1006551011874	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1006551011875	inner membrane protein; Provisional; Region: PRK11648
1006551011876	2-deoxy-D-gluconate 3-dehydrogenase; Validated; Region: PRK08993
1006551011877	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1006551011878	NADP binding site [chemical binding]; other site
1006551011879	homodimer interface [polypeptide binding]; other site
1006551011880	active site
1006551011881	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
1006551011882	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1006551011883	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1006551011884	motif II; other site
1006551011885	YniB-like protein; Region: YniB; pfam14002
1006551011886	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
1006551011887	outer membrane receptor FepA; Provisional; Region: PRK13528
1006551011888	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1006551011889	N-terminal plug; other site
1006551011890	ligand-binding site [chemical binding]; other site
1006551011891	ClC sycA-like chloride channel proteins. This ClC family presents in bacteria, where it facilitates acid resistance in acidic soil. Mutation of this gene (sycA) in Rhizobium tropici CIAT899 causes serious deficiencies in nodule development, nodulation...; Region: ClC_sycA_like; cd03682
1006551011892	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1006551011893	putative Cl- selectivity filter; other site
1006551011894	putative pore gating glutamate residue; other site
1006551011895	intracellular septation protein A; Reviewed; Region: PRK00259
1006551011896	hypothetical protein; Provisional; Region: PRK02868
1006551011897	outer membrane protein W; Provisional; Region: PRK10959
1006551011898	Protein of unknown function (DUF2543); Region: DUF2543; pfam10820
1006551011899	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1006551011900	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1006551011901	DNA binding residues [nucleotide binding]
1006551011902	dimerization interface [polypeptide binding]; other site
1006551011903	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1006551011904	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551011905	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
1006551011906	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1006551011907	C factor cell-cell signaling protein; Provisional; Region: PRK09009
1006551011908	NAD(P) binding site [chemical binding]; other site
1006551011909	active site
1006551011910	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551011911	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551011912	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator similar to DntR, which is involved in the catabolism of dinitrotoluene; contains the type 2 periplasmic binding fold; Region: PBP2_DntR_like_1; cd08460
1006551011913	putative substrate binding pocket [chemical binding]; other site
1006551011914	putative dimerization interface [polypeptide binding]; other site
1006551011915	Cytochrome P450; Provisional; Region: PLN00168
1006551011916	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
1006551011917	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
1006551011918	substrate binding site [chemical binding]; other site
1006551011919	active site
1006551011920	catalytic residues [active]
1006551011921	heterodimer interface [polypeptide binding]; other site
1006551011922	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
1006551011923	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
1006551011924	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551011925	catalytic residue [active]
1006551011926	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
1006551011927	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
1006551011928	active site
1006551011929	ribulose/triose binding site [chemical binding]; other site
1006551011930	phosphate binding site [ion binding]; other site
1006551011931	substrate (anthranilate) binding pocket [chemical binding]; other site
1006551011932	product (indole) binding pocket [chemical binding]; other site
1006551011933	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
1006551011934	active site
1006551011935	bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase; Provisional; Region: PRK09522
1006551011936	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1006551011937	glutamine binding [chemical binding]; other site
1006551011938	catalytic triad [active]
1006551011939	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1006551011940	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1006551011941	anthranilate synthase component I; Provisional; Region: PRK13564
1006551011942	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1006551011943	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1006551011944	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
1006551011945	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1006551011946	active site
1006551011947	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1006551011948	hypothetical protein; Provisional; Region: PRK11630
1006551011949	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
1006551011950	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1006551011951	RNA binding surface [nucleotide binding]; other site
1006551011952	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
1006551011953	probable active site [active]
1006551011954	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1006551011955	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551011956	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1006551011957	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1006551011958	Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915
1006551011959	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1006551011960	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1006551011961	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1006551011962	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551011963	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551011964	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
1006551011965	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
1006551011966	homodimer interface [polypeptide binding]; other site
1006551011967	Walker A motif; other site
1006551011968	ATP binding site [chemical binding]; other site
1006551011969	hydroxycobalamin binding site [chemical binding]; other site
1006551011970	Walker B motif; other site
1006551011971	putative oxoacyl-(acyl carrier protein) reductase; Provisional; Region: PRK08945
1006551011972	Escherichia coli K-12 YCIK-like, classical (c) SDRs; Region: Ycik_SDR_c; cd05340
1006551011973	NADP binding site [chemical binding]; other site
1006551011974	homodimer interface [polypeptide binding]; other site
1006551011975	active site
1006551011976	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
1006551011977	putative inner membrane peptidase; Provisional; Region: PRK11778
1006551011978	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1006551011979	tandem repeat interface [polypeptide binding]; other site
1006551011980	oligomer interface [polypeptide binding]; other site
1006551011981	active site residues [active]
1006551011982	hypothetical protein; Provisional; Region: PRK11037
1006551011983	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
1006551011984	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
1006551011985	active site
1006551011986	interdomain interaction site; other site
1006551011987	putative metal-binding site [ion binding]; other site
1006551011988	nucleotide binding site [chemical binding]; other site
1006551011989	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1006551011990	domain I; other site
1006551011991	DNA binding groove [nucleotide binding]
1006551011992	phosphate binding site [ion binding]; other site
1006551011993	domain II; other site
1006551011994	domain III; other site
1006551011995	nucleotide binding site [chemical binding]; other site
1006551011996	catalytic site [active]
1006551011997	domain IV; other site
1006551011998	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1006551011999	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1006551012000	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
1006551012001	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
1006551012002	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
1006551012003	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551012004	The C-terminal substrate domain of LysR-type transcriptional regulator CysB contains type 2 periplasmic binding fold; Region: PBP2_CysB; cd08443
1006551012005	substrate binding site [chemical binding]; other site
1006551012006	putative dimerization interface [polypeptide binding]; other site
1006551012007	aconitate hydratase; Validated; Region: PRK09277
1006551012008	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
1006551012009	substrate binding site [chemical binding]; other site
1006551012010	ligand binding site [chemical binding]; other site
1006551012011	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
1006551012012	substrate binding site [chemical binding]; other site
1006551012013	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
1006551012014	dimerization interface [polypeptide binding]; other site
1006551012015	active site
1006551012016	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1006551012017	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
1006551012018	active site
1006551012019	Predicted membrane protein [Function unknown]; Region: COG3771
1006551012020	tetratricopeptide repeat protein; Provisional; Region: PRK11788
1006551012021	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1006551012022	TPR motif; other site
1006551012023	binding surface
1006551012024	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
1006551012025	active site
1006551012026	dimer interface [polypeptide binding]; other site
1006551012027	translation initiation factor Sui1; Validated; Region: PRK06824
1006551012028	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
1006551012029	putative rRNA binding site [nucleotide binding]; other site
1006551012030	lipoprotein; Provisional; Region: PRK10540
1006551012031	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1006551012032	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1006551012033	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1006551012034	hypothetical protein; Provisional; Region: PRK13658
1006551012035	exoribonuclease II; Provisional; Region: PRK05054
1006551012036	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1006551012037	RNB domain; Region: RNB; pfam00773
1006551012038	S1 RNA binding domain; Region: S1; pfam00575
1006551012039	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4950; cl17731
1006551012040	Uncharacterized conserved protein [Function unknown]; Region: COG2128
1006551012041	Carboxymuconolactone decarboxylase family; Region: CMD; cl00460
1006551012042	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK07984
1006551012043	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
1006551012044	NAD binding site [chemical binding]; other site
1006551012045	homotetramer interface [polypeptide binding]; other site
1006551012046	homodimer interface [polypeptide binding]; other site
1006551012047	substrate binding site [chemical binding]; other site
1006551012048	active site
1006551012049	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
1006551012050	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1006551012051	Walker A/P-loop; other site
1006551012052	ATP binding site [chemical binding]; other site
1006551012053	Q-loop/lid; other site
1006551012054	ABC transporter signature motif; other site
1006551012055	Walker B; other site
1006551012056	D-loop; other site
1006551012057	H-loop/switch region; other site
1006551012058	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
1006551012059	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1006551012060	Walker A/P-loop; other site
1006551012061	ATP binding site [chemical binding]; other site
1006551012062	Q-loop/lid; other site
1006551012063	ABC transporter signature motif; other site
1006551012064	Walker B; other site
1006551012065	D-loop; other site
1006551012066	H-loop/switch region; other site
1006551012067	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1006551012068	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
1006551012069	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1006551012070	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551012071	putative PBP binding loops; other site
1006551012072	dimer interface [polypeptide binding]; other site
1006551012073	ABC-ATPase subunit interface; other site
1006551012074	antimicrobial peptide ABC transporter permease SapB; Provisional; Region: PRK15110
1006551012075	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551012076	dimer interface [polypeptide binding]; other site
1006551012077	conserved gate region; other site
1006551012078	putative PBP binding loops; other site
1006551012079	ABC-ATPase subunit interface; other site
1006551012080	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1006551012081	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1006551012082	peptide binding site [polypeptide binding]; other site
1006551012083	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551012084	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1006551012085	Beta-xylosidase [Carbohydrate transport and metabolism]; Region: XynB; COG3664
1006551012086	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1006551012087	M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_like1; cd05666
1006551012088	metal binding site [ion binding]; metal-binding site
1006551012089	putative dimer interface [polypeptide binding]; other site
1006551012090	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1006551012091	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551012092	putative substrate translocation pore; other site
1006551012093	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
1006551012094	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1006551012095	Walker A motif; other site
1006551012096	ATP binding site [chemical binding]; other site
1006551012097	Walker B motif; other site
1006551012098	arginine finger; other site
1006551012099	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1006551012100	phage shock protein PspA; Provisional; Region: PRK10698
1006551012101	phage shock protein B; Provisional; Region: pspB; PRK09458
1006551012102	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
1006551012103	phage shock protein C; Region: phageshock_pspC; TIGR02978
1006551012104	peripheral inner membrane phage-shock protein; Provisional; Region: PRK10497
1006551012105	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1006551012106	active site residue [active]
1006551012107	Predicted ATPase [General function prediction only]; Region: COG3106
1006551012108	hypothetical protein; Provisional; Region: PRK05415
1006551012109	Domain of unknown function (DUF697); Region: DUF697; cl12064
1006551012110	DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820
1006551012111	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1006551012112	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1006551012113	putative active site [active]
1006551012114	heme pocket [chemical binding]; other site
1006551012115	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1006551012116	Walker A motif; other site
1006551012117	ATP binding site [chemical binding]; other site
1006551012118	Walker B motif; other site
1006551012119	arginine finger; other site
1006551012120	Putative ammonia monooxygenase [General function prediction only]; Region: AbrB; COG3180
1006551012121	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
1006551012122	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
1006551012123	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
1006551012124	dimer interface [polypeptide binding]; other site
1006551012125	catalytic triad [active]
1006551012126	peroxidatic and resolving cysteines [active]
1006551012127	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
1006551012128	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
1006551012129	active site
1006551012130	Peptidase M14-like domain of Escherichia coli Murein Peptide Amidase A and related proteins; Region: M14_MpaA_like; cd06904
1006551012131	putative active site [active]
1006551012132	Zn binding site [ion binding]; other site
1006551012133	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1006551012134	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1006551012135	peptide binding site [polypeptide binding]; other site
1006551012136	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
1006551012137	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
1006551012138	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1006551012139	Walker A/P-loop; other site
1006551012140	ATP binding site [chemical binding]; other site
1006551012141	Q-loop/lid; other site
1006551012142	ABC transporter signature motif; other site
1006551012143	Walker B; other site
1006551012144	D-loop; other site
1006551012145	H-loop/switch region; other site
1006551012146	NIL domain; Region: NIL; cl09633
1006551012147	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551012148	dimer interface [polypeptide binding]; other site
1006551012149	conserved gate region; other site
1006551012150	ABC-ATPase subunit interface; other site
1006551012151	NLPA lipoprotein; Region: Lipoprotein_9; cl17547
1006551012152	benzoate transport; Region: 2A0115; TIGR00895
1006551012153	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551012154	putative substrate translocation pore; other site
1006551012155	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551012156	sulfur acquisition oxidoreductase, SfnB family; Region: sulfur_SfnB; TIGR04022
1006551012157	Dibenzothiophene (DBT) desulfurization enzyme C; Region: DszC; cd01163
1006551012158	Flavin binding site [chemical binding]; other site
1006551012159	Protein of unknown function (DUF3604); Region: DUF3604; pfam12228
1006551012160	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1006551012161	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551012162	dimer interface [polypeptide binding]; other site
1006551012163	conserved gate region; other site
1006551012164	putative PBP binding loops; other site
1006551012165	ABC-ATPase subunit interface; other site
1006551012166	substrate binding pocket [chemical binding]; other site
1006551012167	NMT1-like family; Region: NMT1_2; pfam13379
1006551012168	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
1006551012169	membrane-bound complex binding site; other site
1006551012170	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551012171	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
1006551012172	ABC transporter signature motif; other site
1006551012173	Walker B; other site
1006551012174	D-loop; other site
1006551012175	H-loop/switch region; other site
1006551012176	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1006551012177	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551012178	DNA-binding site [nucleotide binding]; DNA binding site
1006551012179	UTRA domain; Region: UTRA; pfam07702
1006551012180	chorismate mutase; Provisional; Region: PRK08055
1006551012181	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1006551012182	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551012183	substrate binding pocket [chemical binding]; other site
1006551012184	membrane-bound complex binding site; other site
1006551012185	hinge residues; other site
1006551012186	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1006551012187	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551012188	Walker A/P-loop; other site
1006551012189	ATP binding site [chemical binding]; other site
1006551012190	Q-loop/lid; other site
1006551012191	ABC transporter signature motif; other site
1006551012192	Walker B; other site
1006551012193	D-loop; other site
1006551012194	H-loop/switch region; other site
1006551012195	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1006551012196	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551012197	dimer interface [polypeptide binding]; other site
1006551012198	conserved gate region; other site
1006551012199	putative PBP binding loops; other site
1006551012200	ABC-ATPase subunit interface; other site
1006551012201	HAD-superfamily hydrolase, subfamily IIB; Region: HAD-SF-IIB; TIGR01484
1006551012202	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
1006551012203	active site
1006551012204	motif I; other site
1006551012205	motif II; other site
1006551012206	Serine acetyltransferase, N-terminal; Region: SATase_N; cl05762
1006551012207	serine O-acetyltransferase; Region: cysE; TIGR01172
1006551012208	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1006551012209	trimer interface [polypeptide binding]; other site
1006551012210	active site
1006551012211	substrate binding site [chemical binding]; other site
1006551012212	CoA binding site [chemical binding]; other site
1006551012213	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1006551012214	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1006551012215	dimer interface [polypeptide binding]; other site
1006551012216	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551012217	catalytic residue [active]
1006551012218	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding); Region: MPN_like; cd08070
1006551012219	MPN+ (JAMM) motif; other site
1006551012220	Zinc-binding site [ion binding]; other site
1006551012221	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
1006551012222	MoaE interaction surface [polypeptide binding]; other site
1006551012223	MoeB interaction surface [polypeptide binding]; other site
1006551012224	thiocarboxylated glycine; other site
1006551012225	hypothetical protein; Validated; Region: PRK07411
1006551012226	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1006551012227	ATP binding site [chemical binding]; other site
1006551012228	substrate interface [chemical binding]; other site
1006551012229	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
1006551012230	active site residue [active]
1006551012231	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1006551012232	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1006551012233	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1006551012234	catalytic residue [active]
1006551012235	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1006551012236	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551012237	putative PBP binding loops; other site
1006551012238	dimer interface [polypeptide binding]; other site
1006551012239	ABC-ATPase subunit interface; other site
1006551012240	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
1006551012241	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1006551012242	Walker A/P-loop; other site
1006551012243	ATP binding site [chemical binding]; other site
1006551012244	Q-loop/lid; other site
1006551012245	ABC transporter signature motif; other site
1006551012246	Walker B; other site
1006551012247	D-loop; other site
1006551012248	H-loop/switch region; other site
1006551012249	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
1006551012250	NMT1-like family; Region: NMT1_2; pfam13379
1006551012251	Malate/L-lactate dehydrogenase; Region: Ldh_2; cl00900
1006551012252	D-cysteine desulfhydrase; Validated; Region: PRK03910
1006551012253	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
1006551012254	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1006551012255	catalytic residue [active]
1006551012256	aspartate racemase; Region: asp_race; TIGR00035
1006551012257	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
1006551012258	ABC-type taurine transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: TauA; COG4521
1006551012259	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551012260	substrate binding pocket [chemical binding]; other site
1006551012261	membrane-bound complex binding site; other site
1006551012262	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1006551012263	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551012264	dimer interface [polypeptide binding]; other site
1006551012265	conserved gate region; other site
1006551012266	putative PBP binding loops; other site
1006551012267	ABC-ATPase subunit interface; other site
1006551012268	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
1006551012269	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1006551012270	Walker A/P-loop; other site
1006551012271	ATP binding site [chemical binding]; other site
1006551012272	Q-loop/lid; other site
1006551012273	ABC transporter signature motif; other site
1006551012274	Walker B; other site
1006551012275	D-loop; other site
1006551012276	H-loop/switch region; other site
1006551012277	intracellular protease, PfpI family; Region: PfpI; TIGR01382
1006551012278	Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_1; cd03169
1006551012279	conserved cys residue [active]
1006551012280	Protein of unknown function (DUF770); Region: DUF770; pfam05591
1006551012281	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517
1006551012282	Protein of unknown function (DUF877); Region: DUF877; pfam05943
1006551012283	type VI secretion protein, VC_A0114 family; Region: VI_chp_4; TIGR03353
1006551012284	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
1006551012285	Uncharacterized protein conserved in bacteria (DUF2077); Region: DUF2077; pfam09850
1006551012286	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1006551012287	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1006551012288	ligand binding site [chemical binding]; other site
1006551012289	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
1006551012290	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
1006551012291	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1006551012292	Walker A motif; other site
1006551012293	ATP binding site [chemical binding]; other site
1006551012294	Walker B motif; other site
1006551012295	arginine finger; other site
1006551012296	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1006551012297	Walker A motif; other site
1006551012298	ATP binding site [chemical binding]; other site
1006551012299	Walker B motif; other site
1006551012300	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1006551012301	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
1006551012302	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1006551012303	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1006551012304	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
1006551012305	Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; pfam10106
1006551012306	PAAR motif; Region: PAAR_motif; pfam05488
1006551012307	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
1006551012308	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
1006551012309	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
1006551012310	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
1006551012311	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
1006551012312	Protein of unknown function (DUF1305); Region: DUF1305; pfam06996
1006551012313	Type VI secretion lipoprotein; Region: T6SS-SciN; pfam12790
1006551012314	Gene 25-like lysozyme; Region: GPW_gp25; cl01403
1006551012315	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
1006551012316	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
1006551012317	ImpA domain protein; Region: DUF3702; pfam12486
1006551012318	Beta-xylosidase [Carbohydrate transport and metabolism]; Region: XynB; COG3507
1006551012319	Glycosyl hydrolase family 43, beta-D-xylosidase; Region: GH43_XYL_1; cd09000
1006551012320	inhibitor binding site; inhibition site
1006551012321	active site
1006551012322	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1006551012323	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1006551012324	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1006551012325	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1006551012326	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1006551012327	Uncharacterized conserved protein [Function unknown]; Region: COG1683
1006551012328	Uncharacterized conserved protein [Function unknown]; Region: COG3272
1006551012329	Protein of unknown function (DUF1722); Region: DUF1722; cl01284
1006551012330	Protein of unknown function (DUF3833); Region: DUF3833; pfam12915
1006551012331	Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane]; Region: Cfa; COG2230
1006551012332	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551012333	S-adenosylmethionine binding site [chemical binding]; other site
1006551012334	Protein of unknown function (DUF1365); Region: DUF1365; pfam07103
1006551012335	Predicted NAD/FAD-binding protein [General function prediction only]; Region: COG2907
1006551012336	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1006551012337	short chain dehydrogenase; Provisional; Region: PRK06101
1006551012338	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1006551012339	NAD(P) binding site [chemical binding]; other site
1006551012340	active site
1006551012341	SnoaL-like domain; Region: SnoaL_2; pfam12680
1006551012342	transcriptional regulator MirA; Provisional; Region: PRK15043
1006551012343	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
1006551012344	DNA binding residues [nucleotide binding]
1006551012345	Predicted membrane protein [Function unknown]; Region: COG3326
1006551012346	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1006551012347	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551012348	putative substrate translocation pore; other site
1006551012349	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
1006551012350	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551012351	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551012352	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
1006551012353	putative effector binding pocket; other site
1006551012354	putative dimerization interface [polypeptide binding]; other site
1006551012355	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551012356	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551012357	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
1006551012358	putative effector binding pocket; other site
1006551012359	putative dimerization interface [polypeptide binding]; other site
1006551012360	Dioxygenases related to 2-nitropropane dioxygenase [General function prediction only]; Region: COG2070
1006551012361	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
1006551012362	FMN binding site [chemical binding]; other site
1006551012363	substrate binding site [chemical binding]; other site
1006551012364	putative catalytic residue [active]
1006551012365	short chain dehydrogenase; Validated; Region: PRK06182
1006551012366	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
1006551012367	NADP binding site [chemical binding]; other site
1006551012368	active site
1006551012369	steroid binding site; other site
1006551012370	Arabinose-binding domain of AraC transcription regulator, N-term; Region: Arabinose_bd; pfam12625
1006551012371	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1006551012372	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
1006551012373	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
1006551012374	Protein of unknown function (DUF1440); Region: DUF1440; cl01380
1006551012375	PTS_IIB: subunit IIB of enzyme II (EII) is the central energy-coupling domain of the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In the multienzyme PTS complex, EII is a carbohydrate-specific permease consisting of two cytoplasmic...; Region: PTS_IIB; cl10014
1006551012376	active site
1006551012377	P-loop; other site
1006551012378	phosphorylation site [posttranslational modification]
1006551012379	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
1006551012380	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1006551012381	Catalytic site [active]
1006551012382	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
1006551012383	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
1006551012384	active site
1006551012385	DNA binding site [nucleotide binding]
1006551012386	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1006551012387	putative oxidoreductase; Provisional; Region: PRK11579
1006551012388	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1006551012389	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1006551012390	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1006551012391	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1006551012392	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1006551012393	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1006551012394	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1006551012395	DNA binding residues [nucleotide binding]
1006551012396	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1006551012397	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
1006551012398	Cl binding site [ion binding]; other site
1006551012399	oligomer interface [polypeptide binding]; other site
1006551012400	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
1006551012401	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1006551012402	ATP binding site [chemical binding]; other site
1006551012403	Mg++ binding site [ion binding]; other site
1006551012404	motif III; other site
1006551012405	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1006551012406	nucleotide binding region [chemical binding]; other site
1006551012407	ATP-binding site [chemical binding]; other site
1006551012408	RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501
1006551012409	putative RNA binding site [nucleotide binding]; other site
1006551012410	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
1006551012411	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
1006551012412	Ligand Binding Site [chemical binding]; other site
1006551012413	outer membrane protease; Reviewed; Region: PRK10993
1006551012414	Bor protein; Region: Lambda_Bor; pfam06291
1006551012415	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1006551012416	Ligand Binding Site [chemical binding]; other site
1006551012417	KTSC domain; Region: KTSC; pfam13619
1006551012418	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1006551012419	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1006551012420	trimer interface [polypeptide binding]; other site
1006551012421	eyelet of channel; other site
1006551012422	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
1006551012423	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
1006551012424	dimer interface [polypeptide binding]; other site
1006551012425	PYR/PP interface [polypeptide binding]; other site
1006551012426	TPP binding site [chemical binding]; other site
1006551012427	substrate binding site [chemical binding]; other site
1006551012428	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
1006551012429	Domain of unknown function; Region: EKR; pfam10371
1006551012430	4Fe-4S binding domain; Region: Fer4_6; pfam12837
1006551012431	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1006551012432	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
1006551012433	TPP-binding site [chemical binding]; other site
1006551012434	dimer interface [polypeptide binding]; other site
1006551012435	Predicted transcriptional regulator [Transcription]; Region: COG2932
1006551012436	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1006551012437	Catalytic site [active]
1006551012438	Protein of unknown function (DUF754); Region: DUF754; pfam05449
1006551012439	Lysozyme family protein [General function prediction only]; Region: zliS; COG3926
1006551012440	Glycosyl hydrolase 108; Region: Glyco_hydro_108; pfam05838
1006551012441	Predicted Peptidoglycan domain; Region: PG_binding_3; pfam09374
1006551012442	Phage tail protein; Region: Phage_tail_3; pfam08813
1006551012443	Domain of unknown function (DUF1789); Region: DUF1789; pfam08748
1006551012444	phage tail tape measure protein, lambda family; Region: tape_meas_lam_C; TIGR01541
1006551012445	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
1006551012446	Phage minor tail protein; Region: Phage_min_tail; pfam05939
1006551012447	Phage minor tail protein L; Region: Phage_tail_L; cl01908
1006551012448	Mpr1p, Pad1p N-terminal (MPN) domains; Region: MPN; cl13996
1006551012449	NlpC/P60 family; Region: NLPC_P60; pfam00877
1006551012450	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1006551012451	Phage-related protein, tail component [Function unknown]; Region: COG4723
1006551012452	Phage-related protein, tail component [Function unknown]; Region: COG4733
1006551012453	Putative phage tail protein; Region: Phage-tail_3; pfam13550
1006551012454	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1006551012455	Interdomain contacts; other site
1006551012456	Cytokine receptor motif; other site
1006551012457	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
1006551012458	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
1006551012459	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
1006551012460	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
1006551012461	Fibronectin type III protein; Region: DUF3672; pfam12421
1006551012462	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
1006551012463	Domain of unknown function (DUF333); Region: DUF333; pfam03891
1006551012464	META domain; Region: META; cl01245
1006551012465	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
1006551012466	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
1006551012467	putative ligand binding site [chemical binding]; other site
1006551012468	putative NAD binding site [chemical binding]; other site
1006551012469	catalytic site [active]
1006551012470	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1006551012471	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1006551012472	hypothetical protein; Provisional; Region: PRK10695
1006551012473	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
1006551012474	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3784
1006551012475	DNA-binding transcriptional activator FeaR; Provisional; Region: PRK09685
1006551012476	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551012477	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
1006551012478	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1006551012479	NAD(P) binding site [chemical binding]; other site
1006551012480	catalytic residues [active]
1006551012481	hypothetical protein; Provisional; Region: PRK07490
1006551012482	active site
1006551012483	Zn2+ binding site [ion binding]; other site
1006551012484	intersubunit interface [polypeptide binding]; other site
1006551012485	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551012486	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1006551012487	substrate binding pocket [chemical binding]; other site
1006551012488	membrane-bound complex binding site; other site
1006551012489	hinge residues; other site
1006551012490	Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; pfam05721
1006551012491	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551012492	dimer interface [polypeptide binding]; other site
1006551012493	conserved gate region; other site
1006551012494	putative PBP binding loops; other site
1006551012495	ABC-ATPase subunit interface; other site
1006551012496	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1006551012497	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1006551012498	Walker A/P-loop; other site
1006551012499	ATP binding site [chemical binding]; other site
1006551012500	Q-loop/lid; other site
1006551012501	ABC transporter signature motif; other site
1006551012502	Walker B; other site
1006551012503	D-loop; other site
1006551012504	H-loop/switch region; other site
1006551012505	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551012506	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551012507	The C-terminal substrate-binding domain of putative LysR-type transcriptional regulator PAO1-like, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_PAO1_like; cd08412
1006551012508	putative substrate binding pocket [chemical binding]; other site
1006551012509	dimerization interface [polypeptide binding]; other site
1006551012510	flavin-dependent oxidoreductase, MSMEG_0569 family; Region: MSMEG_0569_nitr; TIGR04046
1006551012511	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1006551012512	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1006551012513	homotrimer interaction site [polypeptide binding]; other site
1006551012514	putative active site [active]
1006551012515	Family of unknown function (DUF1028); Region: DUF1028; pfam06267
1006551012516	acetylornithine deacetylase; Provisional; Region: PRK07522
1006551012517	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
1006551012518	metal binding site [ion binding]; metal-binding site
1006551012519	putative dimer interface [polypeptide binding]; other site
1006551012520	Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; cl17312
1006551012521	DinB family; Region: DinB; cl17821
1006551012522	DinB superfamily; Region: DinB_2; pfam12867
1006551012523	RibD C-terminal domain; Region: RibD_C; cl17279
1006551012524	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1006551012525	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
1006551012526	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1006551012527	Cupin domain; Region: Cupin_2; cl17218
1006551012528	Cupin domain; Region: Cupin_2; cl17218
1006551012529	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
1006551012530	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1006551012531	HlyD family secretion protein; Region: HlyD_3; pfam13437
1006551012532	Fusaric acid resistance protein family; Region: FUSC; pfam04632
1006551012533	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1006551012534	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1006551012535	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551012536	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1006551012537	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551012538	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551012539	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1006551012540	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1006551012541	HlyD family secretion protein; Region: HlyD_3; pfam13437
1006551012542	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1006551012543	Predicted transcriptional regulator [Transcription]; Region: COG1959
1006551012544	Transcriptional regulator; Region: Rrf2; pfam02082
1006551012545	Transcriptional regulator; Region: Rrf2; cl17282
1006551012546	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1006551012547	catalytic core [active]
1006551012548	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1006551012549	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1006551012550	Predicted transcriptional regulator [Transcription]; Region: COG2378
1006551012551	HTH domain; Region: HTH_11; pfam08279
1006551012552	WYL domain; Region: WYL; pfam13280
1006551012553	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1006551012554	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1006551012555	NAD(P) binding site [chemical binding]; other site
1006551012556	active site
1006551012557	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1006551012558	TPR motif; other site
1006551012559	binding surface
1006551012560	TPR repeat; Region: TPR_11; pfam13414
1006551012561	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1006551012562	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551012563	DNA-binding site [nucleotide binding]; DNA binding site
1006551012564	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1006551012565	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551012566	homodimer interface [polypeptide binding]; other site
1006551012567	catalytic residue [active]
1006551012568	N-acetyltransferase; Region: Acetyltransf_2; pfam00797
1006551012569	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
1006551012570	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1006551012571	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1006551012572	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977
1006551012573	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137
1006551012574	conserved cys residue [active]
1006551012575	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551012576	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551012577	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1006551012578	Coenzyme A binding pocket [chemical binding]; other site
1006551012579	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1006551012580	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551012581	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1006551012582	putative effector binding pocket; other site
1006551012583	dimerization interface [polypeptide binding]; other site
1006551012584	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1006551012585	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1006551012586	NAD(P) binding site [chemical binding]; other site
1006551012587	active site
1006551012588	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1006551012589	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3813
1006551012590	Protein of unknown function (DUF1272); Region: DUF1272; pfam06906
1006551012591	Predicted alpha/beta hydrolase [General function prediction only]; Region: COG4757
1006551012592	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_19; cd07262
1006551012593	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1006551012594	tyramine oxidase; Provisional; Region: tynA; PRK14696
1006551012595	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1006551012596	Copper amine oxidase, N2 domain; Region: Cu_amine_oxidN2; pfam02727
1006551012597	Copper amine oxidase, N3 domain; Region: Cu_amine_oxidN3; pfam02728
1006551012598	Copper amine oxidase, enzyme domain; Region: Cu_amine_oxid; pfam01179
1006551012599	bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase; Provisional; Region: PRK11563
1006551012600	N-terminal domain of the monoamine oxidase C dehydratase; Region: ALDH_MaoC-N; cd07128
1006551012601	substrate binding site [chemical binding]; other site
1006551012602	dimer interface [polypeptide binding]; other site
1006551012603	NADP binding site [chemical binding]; other site
1006551012604	catalytic residues [active]
1006551012605	MaoC_C  The C-terminal hot dog fold of the MaoC (monoamine oxidase C) dehydratase regulatory protein. Orthologs of MaoC include PaaZ [Escherichia coli] and PaaN [Pseudomonas putida], which are putative ring-opening enzymes involved in phenylacetic acid...; Region: MaoC_C; cd03452
1006551012606	substrate binding site [chemical binding]; other site
1006551012607	phenylacetate-CoA oxygenase subunit PaaA; Provisional; Region: paaA; PRK13778
1006551012608	phenylacetate-CoA oxygenase, PaaG subunit; Region: PA_CoA_Oxy1; TIGR02156
1006551012609	phenylacetate-CoA oxygenase subunit PaaB; Provisional; Region: paaB; PRK13781
1006551012610	Phenylacetic acid catabolic protein; Region: PaaA_PaaC; pfam05138
1006551012611	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
1006551012612	phenylacetate-CoA oxygenase, PaaJ subunit; Region: PA_CoA_Oxy4; TIGR02159
1006551012613	phenylacetate-CoA oxygenase/reductase, PaaK subunit; Region: PA_CoA_Oxy5; TIGR02160
1006551012614	NAD(P) binding domain of ferredoxin reductase like phenylacetic acid (PA) degradation oxidoreductase. PA oxidoreductases of E. coli hydroxylate PA-CoA in the second step of PA degradation. Members of this group typically fuse a ferredoxin reductase-like...; Region: PA_degradation_oxidoreductase_like; cd06214
1006551012615	FAD binding pocket [chemical binding]; other site
1006551012616	FAD binding motif [chemical binding]; other site
1006551012617	phosphate binding motif [ion binding]; other site
1006551012618	beta-alpha-beta structure motif; other site
1006551012619	NAD(p) ribose binding residues [chemical binding]; other site
1006551012620	NAD binding pocket [chemical binding]; other site
1006551012621	NAD(P)-pyrophosphate-nicotinamide binding residues [chemical binding]; other site
1006551012622	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1006551012623	catalytic loop [active]
1006551012624	iron binding site [ion binding]; other site
1006551012625	enoyl-CoA hydratase-isomerase; Provisional; Region: PRK09674
1006551012626	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1006551012627	substrate binding site [chemical binding]; other site
1006551012628	oxyanion hole (OAH) forming residues; other site
1006551012629	trimer interface [polypeptide binding]; other site
1006551012630	enoyl-CoA hydratase; Provisional; Region: PRK08140
1006551012631	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1006551012632	substrate binding site [chemical binding]; other site
1006551012633	oxyanion hole (OAH) forming residues; other site
1006551012634	trimer interface [polypeptide binding]; other site
1006551012635	3-hydroxy-acyl-CoA dehydrogenase; Validated; Region: PRK08268
1006551012636	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1006551012637	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1006551012638	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1006551012639	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1006551012640	CoenzymeA binding site [chemical binding]; other site
1006551012641	subunit interaction site [polypeptide binding]; other site
1006551012642	PHB binding site; other site
1006551012643	beta-ketoadipyl CoA thiolase; Validated; Region: PRK09050
1006551012644	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1006551012645	dimer interface [polypeptide binding]; other site
1006551012646	active site
1006551012647	Phenylacetate-CoA ligase (also known as PaaK); Region: PaaK; cd05913
1006551012648	phenylacetate-CoA ligase; Region: PA_CoA_ligase; TIGR02155
1006551012649	active site
1006551012650	AMP binding site [chemical binding]; other site
1006551012651	homodimer interface [polypeptide binding]; other site
1006551012652	acyl-activating enzyme (AAE) consensus motif; other site
1006551012653	CoA binding site [chemical binding]; other site
1006551012654	PaaX-like protein; Region: PaaX; pfam07848
1006551012655	phenylacetic acid degradation operon negative regulatory protein PaaX; Region: PaaX_trns_reg; TIGR02277
1006551012656	PaaX-like protein C-terminal domain; Region: PaaX_C; pfam08223
1006551012657	phenylacetic acid degradation protein PaaY; Region: PaaY; TIGR02287
1006551012658	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
1006551012659	putative trimer interface [polypeptide binding]; other site
1006551012660	putative metal binding site [ion binding]; other site
1006551012661	Uncharacterized conserved protein [Function unknown]; Region: COG3791
1006551012662	azoreductase; Reviewed; Region: PRK00170
1006551012663	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1006551012664	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
1006551012665	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1006551012666	ATP binding site [chemical binding]; other site
1006551012667	putative Mg++ binding site [ion binding]; other site
1006551012668	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1006551012669	nucleotide binding region [chemical binding]; other site
1006551012670	ATP-binding site [chemical binding]; other site
1006551012671	Helicase associated domain (HA2); Region: HA2; pfam04408
1006551012672	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
1006551012673	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
1006551012674	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
1006551012675	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551012676	S-adenosylmethionine binding site [chemical binding]; other site
1006551012677	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
1006551012678	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
1006551012679	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1006551012680	HlyD family secretion protein; Region: HlyD_3; pfam13437
1006551012681	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551012682	putative substrate translocation pore; other site
1006551012683	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1006551012684	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
1006551012685	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
1006551012686	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1006551012687	NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; Region: NAD_bind_1_Glu_DH; cd01076
1006551012688	NAD(P) binding site [chemical binding]; other site
1006551012689	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1006551012690	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1006551012691	putative active site [active]
1006551012692	Escherichia coli lactaldehyde dehydrogenase AldA-like; Region: ALDH_LactADH-AldA; cd07088
1006551012693	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1006551012694	NAD binding site [chemical binding]; other site
1006551012695	catalytic residues [active]
1006551012696	substrate binding site [chemical binding]; other site
1006551012697	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
1006551012698	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1006551012699	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1006551012700	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1006551012701	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1006551012702	Coenzyme A binding pocket [chemical binding]; other site
1006551012703	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551012704	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551012705	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1006551012706	dimerization interface [polypeptide binding]; other site
1006551012707	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1006551012708	GAF domain; Region: GAF; pfam01590
1006551012709	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1006551012710	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1006551012711	metal binding site [ion binding]; metal-binding site
1006551012712	active site
1006551012713	I-site; other site
1006551012714	YdfZ protein; Region: YdfZ; cl11878
1006551012715	DinI-like family; Region: DinI; cl11630
1006551012716	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cl00859
1006551012717	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1006551012718	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1006551012719	Coenzyme A binding pocket [chemical binding]; other site
1006551012720	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
1006551012721	putative metal binding site [ion binding]; other site
1006551012722	putative homodimer interface [polypeptide binding]; other site
1006551012723	putative homotetramer interface [polypeptide binding]; other site
1006551012724	putative homodimer-homodimer interface [polypeptide binding]; other site
1006551012725	putative allosteric switch controlling residues; other site
1006551012726	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
1006551012727	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818
1006551012728	substrate binding site [chemical binding]; other site
1006551012729	catalytic Zn binding site [ion binding]; other site
1006551012730	NAD binding site [chemical binding]; other site
1006551012731	structural Zn binding site [ion binding]; other site
1006551012732	dimer interface [polypeptide binding]; other site
1006551012733	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
1006551012734	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
1006551012735	Trp docking motif [polypeptide binding]; other site
1006551012736	putative active site [active]
1006551012737	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
1006551012738	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551012739	The C-terminal substrate binding domain of galactose-binding protein regulator contains the type 2 periplasmic binding fold; Region: PBP2_GbpR; cd08435
1006551012740	putative dimerization interface [polypeptide binding]; other site
1006551012741	Protocatechuate 3,4-dioxygenase beta subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PcaH; COG3485
1006551012742	Protocatechuate 3,4-dioxygenase (3,4-PCD) , alpha subunit. 3,4-PCD catalyzes the oxidative ring cleavage of 3,4-dihydroxybenzoate to produce beta-carboxy-cis,cis-muconate. 3,4-PCDs are large aggregates of 12 protomers, each composed of an alpha- and...; Region: 3,4-PCD_alpha; cd03463
1006551012743	heterodimer interface [polypeptide binding]; other site
1006551012744	active site
1006551012745	Protocatechuate 3,4-dioxygenase (3,4-PCD) , beta subunit. 3,4-PCD catalyzes the oxidative ring cleavage of 3,4-dihydroxybenzoate to produce beta-carboxy-cis,cis-muconate. 3,4-PCDs are large aggregates of 12 protomers, each composed of an alpha- and...; Region: 3,4-PCD_beta; cd03464
1006551012746	heterodimer interface [polypeptide binding]; other site
1006551012747	multimer interface [polypeptide binding]; other site
1006551012748	protocatechuate 3,4-dioxygenase, beta subunit; Region: protocat_beta; TIGR02422
1006551012749	active site
1006551012750	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
1006551012751	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
1006551012752	Carboxylesterase type B [Lipid metabolism]; Region: PnbA; COG2272
1006551012753	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1006551012754	substrate binding pocket [chemical binding]; other site
1006551012755	catalytic triad [active]
1006551012756	Periplasmic glucans biosynthesis protein [Inorganic ion transport and metabolism]; Region: MdoG; COG3131
1006551012757	glucan biosynthesis protein D; Provisional; Region: mdoD; PRK13273
1006551012758	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1006551012759	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1006551012760	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1006551012761	putative trimer interface [polypeptide binding]; other site
1006551012762	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1006551012763	putative trimer interface [polypeptide binding]; other site
1006551012764	putative CoA binding site [chemical binding]; other site
1006551012765	putative CoA binding site [chemical binding]; other site
1006551012766	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cd00208
1006551012767	putative trimer interface [polypeptide binding]; other site
1006551012768	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1006551012769	putative trimer interface [polypeptide binding]; other site
1006551012770	putative CoA binding site [chemical binding]; other site
1006551012771	putative CoA binding site [chemical binding]; other site
1006551012772	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
1006551012773	Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; Region: TDT_TehA; cd09324
1006551012774	gating phenylalanine in ion channel; other site
1006551012775	tellurite resistance protein TehB; Provisional; Region: PRK11207
1006551012776	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551012777	S-adenosylmethionine binding site [chemical binding]; other site
1006551012778	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
1006551012779	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
1006551012780	metal binding site [ion binding]; metal-binding site
1006551012781	dimer interface [polypeptide binding]; other site
1006551012782	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1006551012783	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1006551012784	peptide binding site [polypeptide binding]; other site
1006551012785	Protein of unknown function (DUF3313); Region: DUF3313; pfam11769
1006551012786	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1006551012787	Multidrug resistance efflux transporter; Region: EmrE; pfam13536
1006551012788	EamA-like transporter family; Region: EamA; pfam00892
1006551012789	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551012790	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1006551012791	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551012792	Uncharacterized protein involved in benzoate metabolism [Secondary metabolites biosynthesis, transport, and catabolism]; Region: BenE; COG3135
1006551012793	benzoate transporter; Region: benE; TIGR00843
1006551012794	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1006551012795	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1006551012796	non-specific DNA binding site [nucleotide binding]; other site
1006551012797	salt bridge; other site
1006551012798	sequence-specific DNA binding site [nucleotide binding]; other site
1006551012799	Cupin domain; Region: Cupin_2; pfam07883
1006551012800	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1006551012801	Peptidase family U32; Region: Peptidase_U32; pfam01136
1006551012802	Collagenase; Region: DUF3656; pfam12392
1006551012803	Protein of unknown function (DUF2554); Region: DUF2554; pfam10829
1006551012804	Protein of unknown function (DUF2474); Region: DUF2474; pfam10617
1006551012805	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
1006551012806	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1006551012807	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
1006551012808	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1006551012809	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551012810	DNA-binding site [nucleotide binding]; DNA binding site
1006551012811	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1006551012812	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551012813	homodimer interface [polypeptide binding]; other site
1006551012814	catalytic residue [active]
1006551012815	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
1006551012816	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1006551012817	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
1006551012818	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551012819	Walker A/P-loop; other site
1006551012820	ATP binding site [chemical binding]; other site
1006551012821	Q-loop/lid; other site
1006551012822	ABC transporter signature motif; other site
1006551012823	Walker B; other site
1006551012824	D-loop; other site
1006551012825	H-loop/switch region; other site
1006551012826	TOBE domain; Region: TOBE_2; pfam08402
1006551012827	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
1006551012828	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551012829	dimer interface [polypeptide binding]; other site
1006551012830	conserved gate region; other site
1006551012831	putative PBP binding loops; other site
1006551012832	ABC-ATPase subunit interface; other site
1006551012833	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1006551012834	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
1006551012835	gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK13473
1006551012836	Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like; Region: ALDH_ABALDH-YdcW; cd07092
1006551012837	tetrameric interface [polypeptide binding]; other site
1006551012838	NAD binding site [chemical binding]; other site
1006551012839	catalytic residues [active]
1006551012840	substrate binding site [chemical binding]; other site
1006551012841	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
1006551012842	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1006551012843	Novel bacterial esterase that cleaves esters on halogenated cyclic compounds; Region: Esterase_713_like; cl17303
1006551012844	catalytic site [active]
1006551012845	acyl-CoA thioesterase; Provisional; Region: PRK10531
1006551012846	putative pectinesterase; Region: PLN02432; cl01911
1006551012847	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
1006551012848	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1006551012849	NAD(P) binding site [chemical binding]; other site
1006551012850	catalytic residues [active]
1006551012851	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1006551012852	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1006551012853	peptide binding site [polypeptide binding]; other site
1006551012854	Protein of unknown function (DUF2526); Region: DUF2526; pfam10735
1006551012855	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
1006551012856	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
1006551012857	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1006551012858	Coenzyme A binding pocket [chemical binding]; other site
1006551012859	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1006551012860	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1006551012861	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1006551012862	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1006551012863	sequence-specific DNA binding site [nucleotide binding]; other site
1006551012864	salt bridge; other site
1006551012865	Cupin domain; Region: Cupin_2; pfam07883
1006551012866	Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130
1006551012867	Prostaglandin dehydrogenases; Region: PGDH; cd05288
1006551012868	NAD(P) binding site [chemical binding]; other site
1006551012869	substrate binding site [chemical binding]; other site
1006551012870	dimer interface [polypeptide binding]; other site
1006551012871	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
1006551012872	active site
1006551012873	tetramer interface [polypeptide binding]; other site
1006551012874	hypothetical protein; Provisional; Region: PRK09981
1006551012875	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1006551012876	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1006551012877	N-terminal plug; other site
1006551012878	ligand-binding site [chemical binding]; other site
1006551012879	PQQ-like domain; Region: PQQ_2; pfam13360
1006551012880	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
1006551012881	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1006551012882	L-asparagine permease; Provisional; Region: PRK15049
1006551012883	topology modulation protein; Provisional; Region: PRK07261
1006551012884	AAA domain; Region: AAA_17; pfam13207
1006551012885	luciferase family oxidoreductase, group 1; Region: oxido_grp_1; TIGR03558
1006551012886	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
1006551012887	M20 Peptidase Aminoacyclase-1 YxeP-like proteins, including YxeP, YtnL, YjiB and HipO2; Region: M20_Acy1_YxeP_like; cd05669
1006551012888	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1006551012889	metal binding site [ion binding]; metal-binding site
1006551012890	dimer interface [polypeptide binding]; other site
1006551012891	nitrilotriacetate monoxygenase oxidizes nitrilotriacetate utilizing reduced flavin mononucleotide (FMNH2) and oxygen. The FMNH2 is provided by an NADH:flavin mononucleotide (FMN) oxidorductase that uses NADH to reduce FMN to FMNH2; Region: Nitrilotriacetate_monoxgenase; cd01095
1006551012892	FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family; Region: FMN_nitrolo; TIGR03860
1006551012893	active site
1006551012894	non-prolyl cis peptide bond; other site
1006551012895	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1006551012896	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551012897	substrate binding pocket [chemical binding]; other site
1006551012898	membrane-bound complex binding site; other site
1006551012899	hinge residues; other site
1006551012900	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1006551012901	Coenzyme A binding pocket [chemical binding]; other site
1006551012902	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551012903	dimer interface [polypeptide binding]; other site
1006551012904	conserved gate region; other site
1006551012905	putative PBP binding loops; other site
1006551012906	ABC-ATPase subunit interface; other site
1006551012907	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1006551012908	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551012909	Walker A/P-loop; other site
1006551012910	ATP binding site [chemical binding]; other site
1006551012911	Q-loop/lid; other site
1006551012912	ABC transporter signature motif; other site
1006551012913	Walker B; other site
1006551012914	D-loop; other site
1006551012915	H-loop/switch region; other site
1006551012916	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1006551012917	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551012918	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1006551012919	substrate binding pocket [chemical binding]; other site
1006551012920	membrane-bound complex binding site; other site
1006551012921	hinge residues; other site
1006551012922	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551012923	D-galactonate transporter; Region: 2A0114; TIGR00893
1006551012924	putative substrate translocation pore; other site
1006551012925	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
1006551012926	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
1006551012927	active site pocket [active]
1006551012928	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1006551012929	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1006551012930	DNA binding site [nucleotide binding]
1006551012931	domain linker motif; other site
1006551012932	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1006551012933	putative dimerization interface [polypeptide binding]; other site
1006551012934	putative ligand binding site [chemical binding]; other site
1006551012935	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
1006551012936	C-terminal domain interface [polypeptide binding]; other site
1006551012937	GSH binding site (G-site) [chemical binding]; other site
1006551012938	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1006551012939	dimer interface [polypeptide binding]; other site
1006551012940	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776
1006551012941	N-terminal domain interface [polypeptide binding]; other site
1006551012942	dimer interface [polypeptide binding]; other site
1006551012943	substrate binding pocket (H-site) [chemical binding]; other site
1006551012944	4-oxalocrotonate tautomerase; Provisional; Region: PRK01271
1006551012945	active site 1 [active]
1006551012946	dimer interface [polypeptide binding]; other site
1006551012947	hexamer interface [polypeptide binding]; other site
1006551012948	active site 2 [active]
1006551012949	Protein of unknown function (DUF1044); Region: DUF1044; cl01955
1006551012950	Predicted transcriptional regulator [Transcription]; Region: COG2944
1006551012951	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1006551012952	non-specific DNA binding site [nucleotide binding]; other site
1006551012953	salt bridge; other site
1006551012954	sequence-specific DNA binding site [nucleotide binding]; other site
1006551012955	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
1006551012956	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
1006551012957	trimer interface; other site
1006551012958	sugar binding site [chemical binding]; other site
1006551012959	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551012960	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1006551012961	Bacterial alpha-L-rhamnosidase; Region: Bac_rhamnosid; pfam05592
1006551012962	transcriptional activator RhaR; Provisional; Region: PRK13501
1006551012963	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1006551012964	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551012965	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
1006551012966	ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259
1006551012967	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1006551012968	Walker A/P-loop; other site
1006551012969	ATP binding site [chemical binding]; other site
1006551012970	Q-loop/lid; other site
1006551012971	ABC transporter signature motif; other site
1006551012972	Walker B; other site
1006551012973	D-loop; other site
1006551012974	H-loop/switch region; other site
1006551012975	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1006551012976	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1006551012977	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
1006551012978	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551012979	dimer interface [polypeptide binding]; other site
1006551012980	conserved gate region; other site
1006551012981	putative PBP binding loops; other site
1006551012982	ABC-ATPase subunit interface; other site
1006551012983	N-hydroxyarylamine O-acetyltransferase; Provisional; Region: PRK15047
1006551012984	Nitrate reductase gamma subunit; Region: Nitrate_red_gam; cl00959
1006551012985	nitrate reductase 2 subunit delta; Provisional; Region: PRK15054
1006551012986	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
1006551012987	Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013
1006551012988	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
1006551012989	[4Fe-4S] binding site [ion binding]; other site
1006551012990	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1006551012991	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1006551012992	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1006551012993	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
1006551012994	molybdopterin cofactor binding site; other site
1006551012995	nitrite extrusion protein (nitrite facilitator); Region: 2A0108; TIGR00886
1006551012996	TetR family transcriptional regulator; Provisional; Region: PRK14996
1006551012997	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1006551012998	methyl viologen resistance protein SmvA; Provisional; Region: PRK14995
1006551012999	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551013000	putative substrate translocation pore; other site
1006551013001	aromatic amino acid exporter; Provisional; Region: PRK11689
1006551013002	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1006551013003	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1006551013004	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1006551013005	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
1006551013006	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
1006551013007	molybdopterin cofactor binding site; other site
1006551013008	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
1006551013009	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
1006551013010	formate dehydrogenase-N subunit gamma; Provisional; Region: PRK10179
1006551013011	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
1006551013012	MFS transport protein AraJ; Provisional; Region: PRK10091
1006551013013	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551013014	putative substrate translocation pore; other site
1006551013015	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4950; cl17731
1006551013016	alkylhydroperoxidase domain protein, Avi_7169 family; Region: perox_Avi_7169; TIGR04030
1006551013017	uncharacterized peroxidase-related enzyme; Region: peroxid_rel; TIGR01926
1006551013018	putative FMN-dependent luciferase-like monooxygenase, KPN_01858 family; Region: LLM_KPN_01858; TIGR04027
1006551013019	probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858
1006551013020	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
1006551013021	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1006551013022	Walker A/P-loop; other site
1006551013023	ATP binding site [chemical binding]; other site
1006551013024	Q-loop/lid; other site
1006551013025	ABC transporter signature motif; other site
1006551013026	Walker B; other site
1006551013027	D-loop; other site
1006551013028	H-loop/switch region; other site
1006551013029	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1006551013030	Walker A/P-loop; other site
1006551013031	ATP binding site [chemical binding]; other site
1006551013032	Q-loop/lid; other site
1006551013033	ABC transporter signature motif; other site
1006551013034	Walker B; other site
1006551013035	D-loop; other site
1006551013036	H-loop/switch region; other site
1006551013037	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1006551013038	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1006551013039	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551013040	ABC-ATPase subunit interface; other site
1006551013041	putative PBP binding loops; other site
1006551013042	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1006551013043	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
1006551013044	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1006551013045	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_15; cd08492
1006551013046	ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422
1006551013047	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
1006551013048	NAD binding site [chemical binding]; other site
1006551013049	substrate binding site [chemical binding]; other site
1006551013050	catalytic Zn binding site [ion binding]; other site
1006551013051	tetramer interface [polypeptide binding]; other site
1006551013052	structural Zn binding site [ion binding]; other site
1006551013053	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
1006551013054	dimer interface [polypeptide binding]; other site
1006551013055	substrate binding site [chemical binding]; other site
1006551013056	metal binding sites [ion binding]; metal-binding site
1006551013057	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1006551013058	Coenzyme A binding pocket [chemical binding]; other site
1006551013059	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1006551013060	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1006551013061	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1006551013062	malate dehydrogenase; Provisional; Region: PRK13529
1006551013063	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1006551013064	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
1006551013065	NAD(P) binding site [chemical binding]; other site
1006551013066	30S ribosomal protein subunit S22 family; Region: Ribosomal_S22; cl11579
1006551013067	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1006551013068	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551013069	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551013070	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1006551013071	putative effector binding pocket; other site
1006551013072	dimerization interface [polypeptide binding]; other site
1006551013073	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1006551013074	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1006551013075	Coenzyme A binding pocket [chemical binding]; other site
1006551013076	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
1006551013077	Uncharacterized protein conserved in bacteria (DUF2236); Region: DUF2236; cl01472
1006551013078	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1006551013079	cation diffusion facilitator family transporter; Region: CDF; TIGR01297
1006551013080	Bestrophin, RFP-TM, chloride channel; Region: Bestrophin; cl01544
1006551013081	oxidoreductase alpha (molybdopterin) subunit; Region: Fdhalpha-like; TIGR01701
1006551013082	The MopB_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. These members belong to the molybdopterin_binding (MopB) superfamily of proteins; Region: MopB_ydeP; cd02767
1006551013083	putative molybdopterin cofactor binding site [chemical binding]; other site
1006551013084	The MopB_CT_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. This CD is of the conserved molybdopterin_binding C-terminal (MopB_CT) region...; Region: MopB_CT_ydeP; cd02787
1006551013085	putative molybdopterin cofactor binding site; other site
1006551013086	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
1006551013087	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1006551013088	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551013089	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1006551013090	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551013091	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551013092	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551013093	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1006551013094	dimerization interface [polypeptide binding]; other site
1006551013095	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551013096	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551013097	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1006551013098	putative effector binding pocket; other site
1006551013099	dimerization interface [polypeptide binding]; other site
1006551013100	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551013101	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1006551013102	putative substrate translocation pore; other site
1006551013103	benzoate transport; Region: 2A0115; TIGR00895
1006551013104	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551013105	putative substrate translocation pore; other site
1006551013106	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551013107	putative substrate translocation pore; other site
1006551013108	Domain of unknown function (DUF3315); Region: DUF3315; cl02275
1006551013109	magnesium transport protein MgtC; Provisional; Region: PRK15385
1006551013110	MgtC family; Region: MgtC; pfam02308
1006551013111	magnesium-transporting ATPase; Provisional; Region: PRK15122
1006551013112	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
1006551013113	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1006551013114	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1006551013115	motif II; other site
1006551013116	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1006551013117	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
1006551013118	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
1006551013119	heme binding site [chemical binding]; other site
1006551013120	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
1006551013121	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551013122	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551013123	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1006551013124	putative effector binding pocket; other site
1006551013125	dimerization interface [polypeptide binding]; other site
1006551013126	Protein of unknown function, DUF606; Region: DUF606; pfam04657
1006551013127	Protein of unknown function, DUF606; Region: DUF606; pfam04657
1006551013128	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
1006551013129	Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only]; Region: COG3382
1006551013130	B3/4 domain; Region: B3_4; pfam03483
1006551013131	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
1006551013132	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1006551013133	non-specific DNA binding site [nucleotide binding]; other site
1006551013134	salt bridge; other site
1006551013135	sequence-specific DNA binding site [nucleotide binding]; other site
1006551013136	Cupin domain; Region: Cupin_2; pfam07883
1006551013137	ABC transporter periplasmic binding protein, urea carboxylase region; Region: ABC_peri_uca; TIGR03427
1006551013138	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
1006551013139	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1006551013140	VPS28 protein; Region: VPS28; pfam03997
1006551013141	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
1006551013142	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1006551013143	nitrate transport ATP-binding subunits C and D; Region: ntrCD; TIGR01184
1006551013144	Walker A/P-loop; other site
1006551013145	ATP binding site [chemical binding]; other site
1006551013146	Q-loop/lid; other site
1006551013147	ABC transporter signature motif; other site
1006551013148	Walker B; other site
1006551013149	D-loop; other site
1006551013150	H-loop/switch region; other site
1006551013151	urea carboxylase-associated protein 2; Region: urea_degr_2; TIGR03425
1006551013152	urea carboxylase-associated protein 1; Region: urea_degr_1; TIGR03424
1006551013153	urea carboxylase-associated protein 1; Region: urea_degr_1; TIGR03424
1006551013154	Domain of unknown function (DUF1989); Region: DUF1989; pfam09347
1006551013155	urea carboxylase; Region: urea_carbox; TIGR02712
1006551013156	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1006551013157	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1006551013158	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1006551013159	Allophanate hydrolase subunit 2; Region: AHS2; smart00797
1006551013160	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; cl00896
1006551013161	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1006551013162	carboxyltransferase (CT) interaction site; other site
1006551013163	biotinylation site [posttranslational modification]; other site
1006551013164	allophanate hydrolase; Provisional; Region: PRK08186
1006551013165	Amidase; Region: Amidase; cl11426
1006551013166	penicillin-binding protein 2; Provisional; Region: PRK10795
1006551013167	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1006551013168	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1006551013169	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
1006551013170	GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518
1006551013171	catalytic triad [active]
1006551013172	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1006551013173	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
1006551013174	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1006551013175	NAD(P) binding site [chemical binding]; other site
1006551013176	active site
1006551013177	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
1006551013178	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551013179	catalytic residue [active]
1006551013180	diaminobutyrate--2-oxoglutarate aminotransferase; Provisional; Region: PRK06931
1006551013181	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1006551013182	inhibitor-cofactor binding pocket; inhibition site
1006551013183	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551013184	catalytic residue [active]
1006551013185	NMT1/THI5 like; Region: NMT1; pfam09084
1006551013186	NLPA lipoprotein; Region: Lipoprotein_9; cl17547
1006551013187	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1006551013188	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551013189	dimer interface [polypeptide binding]; other site
1006551013190	conserved gate region; other site
1006551013191	ABC-ATPase subunit interface; other site
1006551013192	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551013193	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1006551013194	Walker A/P-loop; other site
1006551013195	ATP binding site [chemical binding]; other site
1006551013196	Q-loop/lid; other site
1006551013197	ABC transporter signature motif; other site
1006551013198	Walker B; other site
1006551013199	D-loop; other site
1006551013200	H-loop/switch region; other site
1006551013201	Putative transcription activator [Transcription]; Region: TenA; COG0819
1006551013202	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1006551013203	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1006551013204	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1006551013205	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1006551013206	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1006551013207	DNA binding site [nucleotide binding]
1006551013208	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1006551013209	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
1006551013210	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1006551013211	Secretory lipase; Region: LIP; pfam03583
1006551013212	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1006551013213	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1006551013214	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1006551013215	DNA binding residues [nucleotide binding]
1006551013216	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1006551013217	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1006551013218	AefR-like transcriptional repressor, C-terminal region; Region: TetR_C_7; pfam14246
1006551013219	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
1006551013220	Protein export membrane protein; Region: SecD_SecF; cl14618
1006551013221	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
1006551013222	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
1006551013223	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1649
1006551013224	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1006551013225	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1006551013226	Na(+)-translocating NADH-quinone reductase subunit E; Provisional; Region: PRK02830
1006551013227	C-lysozyme inhibitor; Provisional; Region: PRK09993
1006551013228	Uncharacterized homolog of Blt101 [Function unknown]; Region: COG0401
1006551013229	oxidoreductase; Provisional; Region: PRK06128
1006551013230	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
1006551013231	NAD binding site [chemical binding]; other site
1006551013232	metal binding site [ion binding]; metal-binding site
1006551013233	active site
1006551013234	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1006551013235	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1006551013236	Coenzyme A binding pocket [chemical binding]; other site
1006551013237	N-terminal Early set domain associated with the catalytic domain of Maltooligosyl trehalose trehalohydrolase (also called Glycosyltrehalose trehalohydrolase) and similar proteins; Region: E_set_MTHase_like_N; cd02853
1006551013238	malto-oligosyltrehalose trehalohydrolase; Region: trehalose_TreZ; TIGR02402
1006551013239	Alpha amylase catalytic domain found in Glycosyltrehalose trehalohydrolase (also called Maltooligosyl trehalose Trehalohydrolase); Region: AmyAc_GTHase; cd11325
1006551013240	catalytic site [active]
1006551013241	active site
1006551013242	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
1006551013243	malto-oligosyltrehalose synthase; Region: trehalose_TreY; TIGR02401
1006551013244	Alpha amylase catalytic domain found in maltooligosyl trehalose synthase (MTSase); Region: AmyAc_MTSase; cd11336
1006551013245	active site
1006551013246	catalytic site [active]
1006551013247	glycogen debranching enzyme GlgX; Region: glgX_debranch; TIGR02100
1006551013248	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
1006551013249	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
1006551013250	active site
1006551013251	catalytic site [active]
1006551013252	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06416
1006551013253	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1006551013254	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1006551013255	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1006551013256	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1006551013257	pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; Region: PDHac_trf_mito; TIGR01349
1006551013258	E3 interaction surface; other site
1006551013259	lipoyl attachment site [posttranslational modification]; other site
1006551013260	e3 binding domain; Region: E3_binding; pfam02817
1006551013261	e3 binding domain; Region: E3_binding; pfam02817
1006551013262	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1006551013263	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
1006551013264	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
1006551013265	alpha subunit interface [polypeptide binding]; other site
1006551013266	TPP binding site [chemical binding]; other site
1006551013267	heterodimer interface [polypeptide binding]; other site
1006551013268	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1006551013269	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_y; TIGR03182
1006551013270	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
1006551013271	tetramer interface [polypeptide binding]; other site
1006551013272	TPP-binding site [chemical binding]; other site
1006551013273	heterodimer interface [polypeptide binding]; other site
1006551013274	phosphorylation loop region [posttranslational modification]
1006551013275	ATP-dependent transcriptional regulator [Transcription]; Region: MalT; COG2909
1006551013276	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1006551013277	DNA binding residues [nucleotide binding]
1006551013278	dimerization interface [polypeptide binding]; other site
1006551013279	Broad specificity phosphatase PhoE and related phosphatases [General function prediction only]; Region: phoE; COG0406
1006551013280	Probable cobalt transporter subunit (CbtA); Region: CbtA; cl02266
1006551013281	Probable cobalt transporter subunit (CbtA); Region: CbtA; cl02266
1006551013282	nitrile hydratase accessory protein; Region: nitrile_acc; TIGR03889
1006551013283	Nitrile hydratase beta subunit; Region: NHase_beta; pfam02211
1006551013284	nitrile hydratase, beta subunit; Region: nitrile_beta; TIGR03888
1006551013285	Nitrile hydratase, alpha chain; Region: NHase_alpha; pfam02979
1006551013286	NHLP leader peptide domain; Region: TOMM_pelo; TIGR03793
1006551013287	NHLP leader peptide domain; Region: TOMM_pelo; TIGR03793
1006551013288	amidase; Provisional; Region: PRK07235
1006551013289	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
1006551013290	superfamily containing globins and truncated hemoglobins; Region: globin_like; cl00280
1006551013291	heme-binding site [chemical binding]; other site
1006551013292	Putative MetA-pathway of phenol degradation; Region: Phenol_MetA_deg; pfam13557
1006551013293	DNA-binding transcriptional activator FeaR; Provisional; Region: PRK09685
1006551013294	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1006551013295	Homeodomain-like domain; Region: HTH_23; pfam13384
1006551013296	Winged helix-turn helix; Region: HTH_29; pfam13551
1006551013297	Homeodomain-like domain; Region: HTH_32; pfam13565
1006551013298	SnoaL-like domain; Region: SnoaL_2; pfam12680
1006551013299	Aminoglycoside 3'-phosphotransferase (APH). The APH subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin...; Region: APH; cd05150
1006551013300	Phosphotransferase enzyme family; Region: APH; pfam01636
1006551013301	active site
1006551013302	ATP binding site [chemical binding]; other site
1006551013303	antibiotic binding site [chemical binding]; other site
1006551013304	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase; Region: AAT; pfam03417
1006551013305	glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493
1006551013306	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1006551013307	Walker A/P-loop; other site
1006551013308	ATP binding site [chemical binding]; other site
1006551013309	Q-loop/lid; other site
1006551013310	ABC transporter signature motif; other site
1006551013311	Walker B; other site
1006551013312	D-loop; other site
1006551013313	H-loop/switch region; other site
1006551013314	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551013315	dimer interface [polypeptide binding]; other site
1006551013316	conserved gate region; other site
1006551013317	putative PBP binding loops; other site
1006551013318	ABC-ATPase subunit interface; other site
1006551013319	glutamine ABC transporter periplasmic protein; Reviewed; Region: glnH; PRK09495
1006551013320	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551013321	substrate binding pocket [chemical binding]; other site
1006551013322	membrane-bound complex binding site; other site
1006551013323	hinge residues; other site
1006551013324	hypothetical protein; Provisional; Region: PRK07483
1006551013325	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1006551013326	inhibitor-cofactor binding pocket; inhibition site
1006551013327	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551013328	catalytic residue [active]
1006551013329	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1006551013330	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1006551013331	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1006551013332	putative active site [active]
1006551013333	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1006551013334	non-specific DNA binding site [nucleotide binding]; other site
1006551013335	salt bridge; other site
1006551013336	sequence-specific DNA binding site [nucleotide binding]; other site
1006551013337	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
1006551013338	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1006551013339	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1006551013340	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1006551013341	serine transporter; Region: stp; TIGR00814
1006551013342	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cl02788
1006551013343	salicylate synthase Irp9; Reviewed; Region: PRK06772
1006551013344	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1006551013345	siderophore transporter, RhtX/FptX family; Region: sider_RhtX_FptX; TIGR02718
1006551013346	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1006551013347	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551013348	Walker A/P-loop; other site
1006551013349	ATP binding site [chemical binding]; other site
1006551013350	Q-loop/lid; other site
1006551013351	ABC transporter signature motif; other site
1006551013352	Walker B; other site
1006551013353	D-loop; other site
1006551013354	H-loop/switch region; other site
1006551013355	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1006551013356	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1006551013357	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551013358	Walker A/P-loop; other site
1006551013359	ATP binding site [chemical binding]; other site
1006551013360	Q-loop/lid; other site
1006551013361	ABC transporter signature motif; other site
1006551013362	Walker B; other site
1006551013363	D-loop; other site
1006551013364	H-loop/switch region; other site
1006551013365	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1006551013366	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551013367	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
1006551013368	Condensation domain; Region: Condensation; pfam00668
1006551013369	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1006551013370	Nonribosomal peptide synthase; Region: NRPS; pfam08415
1006551013371	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Streptoalloteichus tallysomycin biosynthesis genes; Region: A_NRPS_TlmIV_like; cd12114
1006551013372	acyl-activating enzyme (AAE) consensus motif; other site
1006551013373	AMP binding site [chemical binding]; other site
1006551013374	Methyltransferase domain; Region: Methyltransf_12; pfam08242
1006551013375	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1006551013376	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1006551013377	Condensation domain; Region: Condensation; pfam00668
1006551013378	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1006551013379	Nonribosomal peptide synthase; Region: NRPS; pfam08415
1006551013380	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1006551013381	potential frameshift: common BLAST hit: gi|51595932|ref|YP_070123.1| yersiniabactin biosynthetic protein
1006551013382	Oxidoreductase (NAD-binding), involved in siderophore biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PchG; COG4693
1006551013383	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1006551013384	Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: GrsT; COG3208
1006551013385	Peptide arylation enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntE; COG1021
1006551013386	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
1006551013387	acyl-activating enzyme (AAE) consensus motif; other site
1006551013388	active site
1006551013389	AMP binding site [chemical binding]; other site
1006551013390	substrate binding site [chemical binding]; other site
1006551013391	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
1006551013392	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1006551013393	N-terminal plug; other site
1006551013394	ligand-binding site [chemical binding]; other site
1006551013395	LysM domain/BON superfamily protein; Provisional; Region: PRK11198
1006551013396	BON domain; Region: BON; pfam04972
1006551013397	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1006551013398	Bacterial protein of unknown function (DUF925); Region: DUF925; pfam06042
1006551013399	PAAR motif; Region: PAAR_motif; pfam05488
1006551013400	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cl02788
1006551013401	Tn3 transposase DDE domain; Region: DDE_Tnp_Tn3; cl14901
1006551013402	TENA/THI-4/PQQC family; Region: TENA_THI-4; cl15243
1006551013403	BtpA family; Region: BtpA; cl00440
1006551013404	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1006551013405	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
1006551013406	substrate binding site [chemical binding]; other site
1006551013407	ATP binding site [chemical binding]; other site
1006551013408	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
1006551013409	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
1006551013410	ligand binding site [chemical binding]; other site
1006551013411	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1006551013412	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1006551013413	DNA binding site [nucleotide binding]
1006551013414	domain linker motif; other site
1006551013415	Ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_LacI_like_11; cd06293
1006551013416	putative dimerization interface [polypeptide binding]; other site
1006551013417	putative ligand binding site [chemical binding]; other site
1006551013418	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
1006551013419	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1006551013420	Walker A/P-loop; other site
1006551013421	ATP binding site [chemical binding]; other site
1006551013422	Q-loop/lid; other site
1006551013423	ABC transporter signature motif; other site
1006551013424	Walker B; other site
1006551013425	D-loop; other site
1006551013426	H-loop/switch region; other site
1006551013427	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1006551013428	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1006551013429	TM-ABC transporter signature motif; other site
1006551013430	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
1006551013431	active site
1006551013432	substrate binding pocket [chemical binding]; other site
1006551013433	homodimer interaction site [polypeptide binding]; other site
1006551013434	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
1006551013435	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK08588
1006551013436	Peptidase M20 acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase (ArgE/DapE)-like; Region: M20_ArgE_DapE_like; cd08659
1006551013437	metal binding site [ion binding]; metal-binding site
1006551013438	dimer interface [polypeptide binding]; other site
1006551013439	TolA C-terminal; Region: TolA; pfam06519
1006551013440	putative outer membrane receptor; Provisional; Region: PRK13513
1006551013441	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1006551013442	N-terminal plug; other site
1006551013443	ligand-binding site [chemical binding]; other site
1006551013444	Uncharacterized conserved protein [Function unknown]; Region: COG3391
1006551013445	Response regulator [Signal transduction mechanisms]; Region: TtrR; COG4566
1006551013446	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551013447	active site
1006551013448	phosphorylation site [posttranslational modification]
1006551013449	intermolecular recognition site; other site
1006551013450	dimerization interface [polypeptide binding]; other site
1006551013451	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1006551013452	DNA binding residues [nucleotide binding]
1006551013453	dimerization interface [polypeptide binding]; other site
1006551013454	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; pfam12974
1006551013455	TRAP transporter solute receptor, TAXI family; Region: TRAP_TAXI; TIGR02122
1006551013456	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1006551013457	dimer interface [polypeptide binding]; other site
1006551013458	phosphorylation site [posttranslational modification]
1006551013459	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551013460	ATP binding site [chemical binding]; other site
1006551013461	Mg2+ binding site [ion binding]; other site
1006551013462	G-X-G motif; other site
1006551013463	tetrathionate reductase subunit B; Provisional; Region: PRK14993
1006551013464	4Fe-4S binding domain; Region: Fer4; pfam00037
1006551013465	tetrathionate reductase subunit C; Provisional; Region: PRK14992
1006551013466	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
1006551013467	tetrathionate reductase subunit A; Provisional; Region: PRK14991
1006551013468	The MopB_Tetrathionate-Ra CD contains tetrathionate reductase, subunit A, (TtrA) and other related proteins. The Salmonella enterica tetrathionate reductase catalyses the reduction of trithionate but not sulfur or thiosulfate. Members of this CD belong...; Region: MopB_Tetrathionate-Ra; cd02758
1006551013469	putative [Fe4-S4] binding site [ion binding]; other site
1006551013470	putative molybdopterin cofactor binding site [chemical binding]; other site
1006551013471	This CD contains the molybdopterin_binding C-terminal (MopB_CT) region of tetrathionate reductase, subunit A, (TtrA); respiratory arsenate As(V) reductase, catalytic subunit (ArrA); and other related proteins; Region: MopB_CT_Tetrathionate_Arsenate-R; cd02780
1006551013472	putative molybdopterin cofactor binding site; other site
1006551013473	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
1006551013474	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1006551013475	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1006551013476	active site
1006551013477	Protein of unknown function (DUF3423); Region: DUF3423; pfam11903
1006551013478	Predicted transcriptional regulators [Transcription]; Region: COG1733
1006551013479	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1006551013480	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235
1006551013481	active site 1 [active]
1006551013482	dimer interface [polypeptide binding]; other site
1006551013483	hexamer interface [polypeptide binding]; other site
1006551013484	active site 2 [active]
1006551013485	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1006551013486	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551013487	S-adenosylmethionine binding site [chemical binding]; other site
1006551013488	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551013489	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551013490	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1006551013491	putative effector binding pocket; other site
1006551013492	dimerization interface [polypeptide binding]; other site
1006551013493	progesterone 5-beta-reductase-like proteins (5beta-POR), atypical (a) SDRs; Region: 5beta-POR_like_SDR_a; cd08948
1006551013494	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1006551013495	NAD(P) binding site [chemical binding]; other site
1006551013496	active site
1006551013497	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1006551013498	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551013499	DNA-binding site [nucleotide binding]; DNA binding site
1006551013500	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
1006551013501	hypothetical protein; Provisional; Region: PRK02947
1006551013502	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1006551013503	putative active site [active]
1006551013504	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK09410
1006551013505	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1006551013506	active site
1006551013507	P-loop; other site
1006551013508	phosphorylation site [posttranslational modification]
1006551013509	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1006551013510	active site
1006551013511	phosphorylation site [posttranslational modification]
1006551013512	Creatinine amidohydrolase; Region: Creatininase; pfam02633
1006551013513	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
1006551013514	active site
1006551013515	substrate binding pocket [chemical binding]; other site
1006551013516	homodimer interaction site [polypeptide binding]; other site
1006551013517	Protein of unknown function (DUF796); Region: DUF796; cl01226
1006551013518	2-dehydropantoate 2-reductase; Provisional; Region: PRK12921
1006551013519	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1006551013520	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
1006551013521	hypothetical protein; Provisional; Region: PRK11415
1006551013522	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1006551013523	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1006551013524	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1006551013525	Uncharacterized conserved protein [Function unknown]; Region: COG4925
1006551013526	Carboxymuconolactone decarboxylase family; Region: CMD; cl00460
1006551013527	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
1006551013528	Flavodoxin-like fold; Region: Flavodoxin_2; pfam02525
1006551013529	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551013530	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551013531	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
1006551013532	putative effector binding pocket; other site
1006551013533	putative dimerization interface [polypeptide binding]; other site
1006551013534	Dienelactone hydrolase family; Region: DLH; pfam01738
1006551013535	Protein of unknown function (DUF1349); Region: DUF1349; pfam07081
1006551013536	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_19; cd07262
1006551013537	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1006551013538	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
1006551013539	conserved cys residue [active]
1006551013540	Protein of unknown function (DUF1062); Region: DUF1062; cl01786
1006551013541	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1006551013542	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1006551013543	DNA binding site [nucleotide binding]
1006551013544	domain linker motif; other site
1006551013545	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1006551013546	ligand binding site [chemical binding]; other site
1006551013547	dimerization interface [polypeptide binding]; other site
1006551013548	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
1006551013549	Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; Region: PBP1_ABC_sugar_binding_like_11; cd06321
1006551013550	putative ligand binding site [chemical binding]; other site
1006551013551	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1006551013552	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1006551013553	Walker A/P-loop; other site
1006551013554	ATP binding site [chemical binding]; other site
1006551013555	Q-loop/lid; other site
1006551013556	ABC transporter signature motif; other site
1006551013557	Walker B; other site
1006551013558	D-loop; other site
1006551013559	H-loop/switch region; other site
1006551013560	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1006551013561	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1006551013562	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1006551013563	TM-ABC transporter signature motif; other site
1006551013564	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1006551013565	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
1006551013566	putative substrate binding site [chemical binding]; other site
1006551013567	putative ATP binding site [chemical binding]; other site
1006551013568	DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes [Carbohydrate transport and metabolism]; Region: FbaB; COG1830
1006551013569	Class I aldolases; Region: Aldolase_Class_I; cl17187
1006551013570	catalytic residue [active]
1006551013571	Glycerol-3-phosphate responsive antiterminator; Region: G3P_antiterm; cl00852
1006551013572	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
1006551013573	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
1006551013574	putative N- and C-terminal domain interface [polypeptide binding]; other site
1006551013575	putative active site [active]
1006551013576	MgATP binding site [chemical binding]; other site
1006551013577	catalytic site [active]
1006551013578	metal binding site [ion binding]; metal-binding site
1006551013579	putative xylulose binding site [chemical binding]; other site
1006551013580	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1006551013581	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1006551013582	NAD(P) binding site [chemical binding]; other site
1006551013583	active site
1006551013584	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_10; cd12171
1006551013585	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
1006551013586	putative ligand binding site [chemical binding]; other site
1006551013587	putative NAD binding site [chemical binding]; other site
1006551013588	catalytic site [active]
1006551013589	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
1006551013590	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
1006551013591	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1006551013592	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1006551013593	trimer interface [polypeptide binding]; other site
1006551013594	eyelet of channel; other site
1006551013595	cupin fold metalloprotein, WbuC family; Region: cupin_WbuC; TIGR04366
1006551013596	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1006551013597	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1006551013598	ABC-ATPase subunit  interface; other site
1006551013599	dimer interface [polypeptide binding]; other site
1006551013600	putative PBP binding regions; other site
1006551013601	Metal binding protein TroA_a.  These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria. They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and...; Region: TroA_a; cd01148
1006551013602	proposed F420-0 ABC transporter, periplasmic F420-0 binding protein; Region: F420-O_ABCperi; TIGR03868
1006551013603	putative ligand binding residues [chemical binding]; other site
1006551013604	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1006551013605	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1006551013606	Walker A/P-loop; other site
1006551013607	ATP binding site [chemical binding]; other site
1006551013608	Q-loop/lid; other site
1006551013609	ABC transporter signature motif; other site
1006551013610	Walker B; other site
1006551013611	D-loop; other site
1006551013612	H-loop/switch region; other site
1006551013613	NIPSNAP; Region: NIPSNAP; pfam07978
1006551013614	Winged helix-turn helix; Region: HTH_29; pfam13551
1006551013615	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1006551013616	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1006551013617	Glycosylasparaginase catalyzes the hydrolysis of the glycosylamide bond of asparagine-linked glycoproteins. This enzyme is an amidase located inside lysosomes. Mutation of this gene in humans causes a genetic disorder known as aspartylglycosaminuria (AGU)...; Region: Glycosylasparaginase; cd04513
1006551013618	dimer interface [polypeptide binding]; other site
1006551013619	active site
1006551013620	catalytic nucleophile [active]
1006551013621	Leucyl aminopeptidase [Amino acid transport and metabolism]; Region: PepB; COG0260
1006551013622	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1006551013623	interface (dimer of trimers) [polypeptide binding]; other site
1006551013624	Substrate-binding/catalytic site; other site
1006551013625	Zn-binding sites [ion binding]; other site
1006551013626	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551013627	putative substrate translocation pore; other site
1006551013628	Cupin; Region: Cupin_6; pfam12852
1006551013629	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1006551013630	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551013631	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551013632	Pyrroline-5-carboxylate reductase [Amino acid transport and metabolism]; Region: ProC; COG0345
1006551013633	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
1006551013634	Glyoxalase-like domain; Region: Glyoxalase_3; pfam13468
1006551013635	L-2-amino-thiazoline-4-carboxylic acid hydrolase; Region: ATC_hydrolase; pfam14196
1006551013636	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551013637	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1006551013638	substrate binding pocket [chemical binding]; other site
1006551013639	membrane-bound complex binding site; other site
1006551013640	hinge residues; other site
1006551013641	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551013642	dimer interface [polypeptide binding]; other site
1006551013643	conserved gate region; other site
1006551013644	putative PBP binding loops; other site
1006551013645	ABC-ATPase subunit interface; other site
1006551013646	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551013647	putative PBP binding loops; other site
1006551013648	dimer interface [polypeptide binding]; other site
1006551013649	ABC-ATPase subunit interface; other site
1006551013650	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1006551013651	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1006551013652	Walker A/P-loop; other site
1006551013653	ATP binding site [chemical binding]; other site
1006551013654	Q-loop/lid; other site
1006551013655	ABC transporter signature motif; other site
1006551013656	Walker B; other site
1006551013657	D-loop; other site
1006551013658	H-loop/switch region; other site
1006551013659	Uncharacterized conserved protein (DUF2132); Region: DUF2132; pfam09905
1006551013660	Isopenicillin N synthase and related dioxygenases [General function prediction only]; Region: PcbC; COG3491
1006551013661	non-haem dioxygenase in morphine synthesis N-terminal; Region: DIOX_N; pfam14226
1006551013662	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy; pfam03171
1006551013663	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1006551013664	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1006551013665	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1006551013666	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1006551013667	Walker A/P-loop; other site
1006551013668	ATP binding site [chemical binding]; other site
1006551013669	Q-loop/lid; other site
1006551013670	ABC transporter signature motif; other site
1006551013671	Walker B; other site
1006551013672	D-loop; other site
1006551013673	H-loop/switch region; other site
1006551013674	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551013675	dimer interface [polypeptide binding]; other site
1006551013676	conserved gate region; other site
1006551013677	ABC-ATPase subunit interface; other site
1006551013678	Nitronate monooxygenase; Region: NMO; pfam03060
1006551013679	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
1006551013680	FMN binding site [chemical binding]; other site
1006551013681	substrate binding site [chemical binding]; other site
1006551013682	putative catalytic residue [active]
1006551013683	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551013684	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551013685	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1006551013686	dimerization interface [polypeptide binding]; other site
1006551013687	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551013688	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1006551013689	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
1006551013690	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
1006551013691	active site
1006551013692	major facilitator superfamily transporter; Provisional; Region: PRK05122
1006551013693	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551013694	putative substrate translocation pore; other site
1006551013695	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
1006551013696	copper/silver efflux system membrane fusion protein CusB; Provisional; Region: PRK09783
1006551013697	HlyD family secretion protein; Region: HlyD_3; pfam13437
1006551013698	Copper binding periplasmic protein CusF; Region: CusF_Ec; pfam11604
1006551013699	Outer membrane efflux protein; Region: OEP; pfam02321
1006551013700	Outer membrane efflux protein; Region: OEP; pfam02321
1006551013701	Copper binding periplasmic protein CusF; Region: CusF_Ec; pfam11604
1006551013702	Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only]; Region: COG1237
1006551013703	Trans-aconitate methyltransferase [General function prediction only]; Region: Tam; COG4106
1006551013704	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551013705	S-adenosylmethionine binding site [chemical binding]; other site
1006551013706	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1006551013707	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1006551013708	Coenzyme A binding pocket [chemical binding]; other site
1006551013709	altronate oxidoreductase; Provisional; Region: PRK03643
1006551013710	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1006551013711	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1006551013712	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
1006551013713	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1006551013714	Coenzyme A binding pocket [chemical binding]; other site
1006551013715	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1006551013716	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1006551013717	metal binding site [ion binding]; metal-binding site
1006551013718	active site
1006551013719	I-site; other site
1006551013720	Domain of unknown function (DUF4186); Region: DUF4186; pfam13811
1006551013721	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
1006551013722	glutaminase; Provisional; Region: PRK00971
1006551013723	putative succinate semialdehyde dehydrogenase; Provisional; Region: PRK13968
1006551013724	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
1006551013725	NAD(P) binding site [chemical binding]; other site
1006551013726	catalytic residues [active]
1006551013727	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
1006551013728	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551013729	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
1006551013730	putative dimerization interface [polypeptide binding]; other site
1006551013731	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1006551013732	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
1006551013733	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1006551013734	L-lactate dehydrogenase; Region: L-LDH-NAD; TIGR01771
1006551013735	NAD binding site [chemical binding]; other site
1006551013736	dimer interface [polypeptide binding]; other site
1006551013737	substrate binding site [chemical binding]; other site
1006551013738	Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384
1006551013739	Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384
1006551013740	putative arabinose transporter; Provisional; Region: PRK03545
1006551013741	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551013742	putative substrate translocation pore; other site
1006551013743	inner membrane protein; Provisional; Region: PRK10995
1006551013744	DNA-binding transcriptional repressor MarR; Provisional; Region: PRK11512
1006551013745	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1006551013746	DNA-binding transcriptional activator MarA; Provisional; Region: PRK11511
1006551013747	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551013748	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551013749	MarB protein; Region: MarB; pfam13999
1006551013750	O-acetylserine/cysteine export protein; Provisional; Region: PRK11453
1006551013751	EamA-like transporter family; Region: EamA; cl17759
1006551013752	putative transporter; Provisional; Region: PRK10054
1006551013753	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551013754	putative substrate translocation pore; other site
1006551013755	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1006551013756	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1006551013757	non-specific DNA binding site [nucleotide binding]; other site
1006551013758	salt bridge; other site
1006551013759	sequence-specific DNA binding site [nucleotide binding]; other site
1006551013760	2TM domain; Region: 2TM; pfam13239
1006551013761	urea ABC transporter, ATP-binding protein UrtE; Region: urea_trans_UrtE; TIGR03410
1006551013762	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
1006551013763	Walker A/P-loop; other site
1006551013764	ATP binding site [chemical binding]; other site
1006551013765	Q-loop/lid; other site
1006551013766	ABC transporter signature motif; other site
1006551013767	Walker B; other site
1006551013768	D-loop; other site
1006551013769	H-loop/switch region; other site
1006551013770	urea ABC transporter, ATP-binding protein UrtD; Region: urea_trans_UrtD; TIGR03411
1006551013771	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
1006551013772	Walker A/P-loop; other site
1006551013773	ATP binding site [chemical binding]; other site
1006551013774	Q-loop/lid; other site
1006551013775	ABC transporter signature motif; other site
1006551013776	Walker B; other site
1006551013777	D-loop; other site
1006551013778	H-loop/switch region; other site
1006551013779	ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177
1006551013780	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
1006551013781	TM-ABC transporter signature motif; other site
1006551013782	HEAT repeats; Region: HEAT_2; pfam13646
1006551013783	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
1006551013784	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1006551013785	TM-ABC transporter signature motif; other site
1006551013786	Periplasmic binding protein; Region: Peripla_BP_6; pfam13458
1006551013787	Periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF); Region: PBP1_FmdD_like; cd06355
1006551013788	putative ligand binding site [chemical binding]; other site
1006551013789	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1006551013790	substrate binding site [chemical binding]; other site
1006551013791	THF binding site; other site
1006551013792	zinc-binding site [ion binding]; other site
1006551013793	Member of the Rhodanese Homology Domain superfamily. This CD includes the putative rhodanese-like protein, Psp2, of Yersinia pestis biovar Medievalis and other similar uncharacterized proteins; Region: RHOD_PspE2; cd01521
1006551013794	active site residue [active]
1006551013795	transcriptional activator FtrA; Provisional; Region: ftrA; PRK09393
1006551013796	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137
1006551013797	conserved cys residue [active]
1006551013798	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551013799	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551013800	methionine synthase; Provisional; Region: PRK01207
1006551013801	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1006551013802	substrate binding site [chemical binding]; other site
1006551013803	THF binding site; other site
1006551013804	zinc-binding site [ion binding]; other site
1006551013805	Domain of unknown function (DUF1852); Region: DUF1852; pfam08908
1006551013806	anti-RssB factor; Provisional; Region: PRK10244
1006551013807	Sensors of blue-light using FAD; Region: BLUF; smart01034
1006551013808	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1006551013809	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1006551013810	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1006551013811	Coenzyme A binding pocket [chemical binding]; other site
1006551013812	lac repressor; Reviewed; Region: lacI; PRK09526
1006551013813	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1006551013814	DNA binding site [nucleotide binding]
1006551013815	domain linker motif; other site
1006551013816	Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_LacI; cd01574
1006551013817	ligand binding site [chemical binding]; other site
1006551013818	dimerization interface (open form) [polypeptide binding]; other site
1006551013819	dimerization interface (closed form) [polypeptide binding]; other site
1006551013820	beta-D-galactosidase; Reviewed; Region: lacZ; PRK09525
1006551013821	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1006551013822	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1006551013823	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1006551013824	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
1006551013825	LacY proton/sugar symporter; Region: LacY_symp; pfam01306
1006551013826	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551013827	putative substrate translocation pore; other site
1006551013828	Predicted ATPase [General function prediction only]; Region: COG4637
1006551013829	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551013830	Walker A/P-loop; other site
1006551013831	ATP binding site [chemical binding]; other site
1006551013832	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551013833	ABC transporter signature motif; other site
1006551013834	Walker B; other site
1006551013835	D-loop; other site
1006551013836	H-loop/switch region; other site
1006551013837	Bacterial protein of unknown function (DUF883); Region: DUF883; pfam05957
1006551013838	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3122
1006551013839	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1006551013840	DNA-binding site [nucleotide binding]; DNA binding site
1006551013841	RNA-binding motif; other site
1006551013842	helix_turn_helix, Lux Regulon; Region: HTH_LUXR; smart00421
1006551013843	DNA binding residues [nucleotide binding]
1006551013844	dipeptidyl carboxypeptidase II; Provisional; Region: PRK10280
1006551013845	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
1006551013846	active site
1006551013847	Zn binding site [ion binding]; other site
1006551013848	malonic semialdehyde reductase; Provisional; Region: PRK10538
1006551013849	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
1006551013850	putative NAD(P) binding site [chemical binding]; other site
1006551013851	homodimer interface [polypeptide binding]; other site
1006551013852	homotetramer interface [polypeptide binding]; other site
1006551013853	active site
1006551013854	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1006551013855	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551013856	DNA-binding site [nucleotide binding]; DNA binding site
1006551013857	FCD domain; Region: FCD; pfam07729
1006551013858	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1006551013859	Ligand Binding Site [chemical binding]; other site
1006551013860	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
1006551013861	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1006551013862	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1006551013863	metabolite-proton symporter; Region: 2A0106; TIGR00883
1006551013864	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551013865	putative substrate translocation pore; other site
1006551013866	putative oxidoreductase; Provisional; Region: PRK10083
1006551013867	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
1006551013868	putative NAD(P) binding site [chemical binding]; other site
1006551013869	catalytic Zn binding site [ion binding]; other site
1006551013870	structural Zn binding site [ion binding]; other site
1006551013871	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
1006551013872	The starvation sensing protein RpsA from E.coli and its homologs are lactonizing enzymes whose putative targets are homoserine lactone (HSL)-derivative. They are part of the mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of...; Region: rpsA; cd03322
1006551013873	putative active site pocket [active]
1006551013874	putative metal binding site [ion binding]; other site
1006551013875	hypothetical protein; Provisional; Region: PRK02237
1006551013876	hypothetical protein; Provisional; Region: PRK13659
1006551013877	spermidine N1-acetyltransferase; Provisional; Region: PRK15130
1006551013878	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1006551013879	Coenzyme A binding pocket [chemical binding]; other site
1006551013880	lipoprotein; Reviewed; Region: PRK02939
1006551013881	Protein of unknown function (DUF1161); Region: DUF1161; pfam06649
1006551013882	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
1006551013883	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1006551013884	putative [Fe4-S4] binding site [ion binding]; other site
1006551013885	putative molybdopterin cofactor binding site [chemical binding]; other site
1006551013886	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1006551013887	putative molybdopterin cofactor binding site; other site
1006551013888	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1006551013889	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
1006551013890	twin-argninine leader-binding protein DmsD; Provisional; Region: PRK11621
1006551013891	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
1006551013892	Cl- selectivity filter; other site
1006551013893	Cl- binding residues [ion binding]; other site
1006551013894	pore gating glutamate residue; other site
1006551013895	dimer interface [polypeptide binding]; other site
1006551013896	putative dithiobiotin synthetase; Provisional; Region: PRK12374
1006551013897	AAA domain; Region: AAA_26; pfam13500
1006551013898	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
1006551013899	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1006551013900	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1006551013901	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551013902	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551013903	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
1006551013904	dimerization interface [polypeptide binding]; other site
1006551013905	substrate binding pocket [chemical binding]; other site
1006551013906	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1006551013907	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551013908	putative substrate translocation pore; other site
1006551013909	Zn-dependent carboxypeptidase [Amino acid transport and metabolism]; Region: COG2317
1006551013910	Peptidase family M32 includes thermostable carboxypeptidases TaqCP and PfuCP; Region: M32_Taq; cd06460
1006551013911	active site
1006551013912	Zn binding site [ion binding]; other site
1006551013913	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
1006551013914	CHASE4 domain; Region: CHASE4; pfam05228
1006551013915	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1006551013916	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1006551013917	metal binding site [ion binding]; metal-binding site
1006551013918	active site
1006551013919	I-site; other site
1006551013920	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1006551013921	multidrug efflux system protein MdtI; Provisional; Region: PRK10650
1006551013922	multidrug efflux system protein MdtJ; Provisional; Region: PRK10452
1006551013923	pheromone autoinducer 2 transporter; Reviewed; Region: tqsA; PRK12287
1006551013924	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1006551013925	malonate decarboxylase, alpha subunit; Region: mdcA; TIGR01110
1006551013926	Coenzyme A transferase; Region: CoA_trans; cl17247
1006551013927	triphosphoribosyl-dephospho-CoA synthase; Validated; Region: PRK01237
1006551013928	malonate decarboxylase acyl carrier protein; Region: malonate_delta; TIGR03130
1006551013929	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189
1006551013930	Malonate decarboxylase gamma subunit (MdcE); Region: MdcE; pfam06833
1006551013931	he Auxin Efflux Carrier (AEC) Family; Region: 2a69; TIGR00946
1006551013932	phosphoribosyl-dephospho-CoA transferase; Provisional; Region: PRK01293
1006551013933	Phosphoribosyl-dephospho-CoA transferase MdcG; Region: MdcG; pfam10620
1006551013934	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1006551013935	malonate decarboxylase, epsilon subunit; Region: malonate_mdcH; TIGR03131
1006551013936	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551013937	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551013938	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1006551013939	dimerization interface [polypeptide binding]; other site
1006551013940	malate:quinone oxidoreductase; Validated; Region: PRK05257
1006551013941	malate:quinone-oxidoreductase; Region: mal_quin_oxido; TIGR01320
1006551013942	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
1006551013943	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
1006551013944	putative active site [active]
1006551013945	short chain dehydrogenase; Provisional; Region: PRK06500
1006551013946	classical (c) SDRs; Region: SDR_c; cd05233
1006551013947	NAD(P) binding site [chemical binding]; other site
1006551013948	active site
1006551013949	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551013950	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551013951	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
1006551013952	putative effector binding pocket; other site
1006551013953	putative dimerization interface [polypeptide binding]; other site
1006551013954	sensory histidine kinase DcuS; Provisional; Region: PRK11086
1006551013955	PAS domain; Region: PAS; smart00091
1006551013956	putative active site [active]
1006551013957	heme pocket [chemical binding]; other site
1006551013958	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551013959	ATP binding site [chemical binding]; other site
1006551013960	Mg2+ binding site [ion binding]; other site
1006551013961	G-X-G motif; other site
1006551013962	DNA-binding transcriptional activator DcuR; Provisional; Region: PRK10430
1006551013963	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551013964	active site
1006551013965	phosphorylation site [posttranslational modification]
1006551013966	intermolecular recognition site; other site
1006551013967	dimerization interface [polypeptide binding]; other site
1006551013968	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
1006551013969	ApbE family; Region: ApbE; pfam02424
1006551013970	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1006551013971	Old yellow enzyme (OYE)-related FMN binding domain, group 4.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as...; Region: OYE_like_4_FMN; cd04735
1006551013972	putative active site [active]
1006551013973	putative FMN binding site [chemical binding]; other site
1006551013974	putative substrate binding site [chemical binding]; other site
1006551013975	putative catalytic residue [active]
1006551013976	FMN-binding domain; Region: FMN_bind; cl01081
1006551013977	flavocytochrome c; Region: flavo_cyto_c; TIGR01813
1006551013978	L-aspartate oxidase; Provisional; Region: PRK06175
1006551013979	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1006551013980	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1006551013981	transmembrane helices; other site
1006551013982	fumarate hydratase; Provisional; Region: PRK15389
1006551013983	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
1006551013984	Fumarase C-terminus; Region: Fumerase_C; pfam05683
1006551013985	4-carboxymuconolactone decarboxylase; Region: decarb_PcaC; TIGR02425
1006551013986	3-oxoadipate enol-lactonase; Region: protocat_pcaD; TIGR02427
1006551013987	3-carboxy-cis,cis-muconate cycloisomerase; Provisional; Region: PRK09053
1006551013988	prokaryotic 3-carboxy-cis,cis-muconate cycloisomerase (CMLE)_like; Region: pCLME; cd01597
1006551013989	tetramer interface [polypeptide binding]; other site
1006551013990	active site
1006551013991	beta-ketoadipyl CoA thiolase; Validated; Region: PRK09050
1006551013992	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1006551013993	dimer interface [polypeptide binding]; other site
1006551013994	active site
1006551013995	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
1006551013996	3-oxoacid CoA-transferase, A subunit; Region: pcaI_scoA_fam; TIGR02429
1006551013997	beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family; Region: pcaR_pcaU; TIGR02431
1006551013998	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1006551013999	Bacterial transcriptional regulator; Region: IclR; pfam01614
1006551014000	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
1006551014001	Smr domain; Region: Smr; pfam01713
1006551014002	putative DNA-binding transcriptional regulator; Provisional; Region: PRK09791
1006551014003	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551014004	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1006551014005	dimerization interface [polypeptide binding]; other site
1006551014006	M20 Peptidases Aminoacyclase-1 indole-3-acetic-L-aspartic acid hydrolase from bacteria and archaea; Region: M20_Acy1_IAAspH_bact; cd05665
1006551014007	amidohydrolase; Region: amidohydrolases; TIGR01891
1006551014008	putative metal binding site [ion binding]; other site
1006551014009	dimer interface [polypeptide binding]; other site
1006551014010	M20 Peptidase Aminoacylase 1-like protein 2 aminobenzoyl-glutamate utilization protein B subfamily; Region: M20_Acy1L2_AbgB; cd05673
1006551014011	amidohydrolase; Region: amidohydrolases; TIGR01891
1006551014012	putative metal binding site [ion binding]; other site
1006551014013	putative aminobenzoyl-glutamate transporter; Provisional; Region: abgT; PRK11339
1006551014014	p-Aminobenzoyl-glutamate transporter family; Region: ydaH; TIGR00819
1006551014015	O-6-alkylguanine-DNA:cysteine-protein methyltransferase; Provisional; Region: PRK10286
1006551014016	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
1006551014017	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1006551014018	DNA binding site [nucleotide binding]
1006551014019	active site
1006551014020	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
1006551014021	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1006551014022	ligand binding site [chemical binding]; other site
1006551014023	flexible hinge region; other site
1006551014024	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1006551014025	putative switch regulator; other site
1006551014026	non-specific DNA interactions [nucleotide binding]; other site
1006551014027	DNA binding site [nucleotide binding]
1006551014028	sequence specific DNA binding site [nucleotide binding]; other site
1006551014029	putative cAMP binding site [chemical binding]; other site
1006551014030	universal stress protein UspE; Provisional; Region: PRK11175
1006551014031	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1006551014032	Ligand Binding Site [chemical binding]; other site
1006551014033	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1006551014034	Ligand Binding Site [chemical binding]; other site
1006551014035	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
1006551014036	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
1006551014037	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
1006551014038	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
1006551014039	ligand binding site [chemical binding]; other site
1006551014040	homodimer interface [polypeptide binding]; other site
1006551014041	NAD(P) binding site [chemical binding]; other site
1006551014042	trimer interface B [polypeptide binding]; other site
1006551014043	trimer interface A [polypeptide binding]; other site
1006551014044	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
1006551014045	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1006551014046	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1006551014047	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1006551014048	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
1006551014049	dihydromonapterin reductase; Provisional; Region: PRK06483
1006551014050	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1006551014051	NAD(P) binding site [chemical binding]; other site
1006551014052	active site
1006551014053	GlpM protein; Region: GlpM; pfam06942
1006551014054	anti-adapter protein IraM; Provisional; Region: PRK09919
1006551014055	DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701
1006551014056	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551014057	active site
1006551014058	phosphorylation site [posttranslational modification]
1006551014059	intermolecular recognition site; other site
1006551014060	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1006551014061	DNA binding site [nucleotide binding]
1006551014062	GAF domain; Region: GAF; pfam01590
1006551014063	GAF domain; Region: GAF_2; pfam13185
1006551014064	Class III nucleotidyl cyclases; Region: Nucleotidyl_cyc_III; cl11967
1006551014065	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1006551014066	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
1006551014067	dimer interface [polypeptide binding]; other site
1006551014068	catalytic residues [active]
1006551014069	Nodulin-21 and CCC1-related protein family; Region: Nodulin-21_like_1; cd02432
1006551014070	sensor protein RstB; Provisional; Region: PRK10604
1006551014071	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1006551014072	dimerization interface [polypeptide binding]; other site
1006551014073	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1006551014074	dimer interface [polypeptide binding]; other site
1006551014075	phosphorylation site [posttranslational modification]
1006551014076	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551014077	ATP binding site [chemical binding]; other site
1006551014078	Mg2+ binding site [ion binding]; other site
1006551014079	G-X-G motif; other site
1006551014080	DNA replication terminus site-binding protein; Provisional; Region: PRK02951
1006551014081	fumarate hydratase; Reviewed; Region: fumC; PRK00485
1006551014082	Class II fumarases; Region: Fumarase_classII; cd01362
1006551014083	active site
1006551014084	tetramer interface [polypeptide binding]; other site
1006551014085	fumarate hydratase; Provisional; Region: PRK15389
1006551014086	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
1006551014087	Fumarase C-terminus; Region: Fumerase_C; pfam05683
1006551014088	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
1006551014089	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
1006551014090	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
1006551014091	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
1006551014092	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
1006551014093	DNA-binding transcriptional repressor MalI; Provisional; Region: PRK10014
1006551014094	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1006551014095	DNA binding site [nucleotide binding]
1006551014096	domain linker motif; other site
1006551014097	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1006551014098	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
1006551014099	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
1006551014100	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1006551014101	active site turn [active]
1006551014102	phosphorylation site [posttranslational modification]
1006551014103	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
1006551014104	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1006551014105	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551014106	homodimer interface [polypeptide binding]; other site
1006551014107	catalytic residue [active]
1006551014108	YdfZ protein; Region: YdfZ; pfam14001
1006551014109	putative inner membrane protein; Provisional; Region: PRK11099
1006551014110	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
1006551014111	CPxP  motif; other site
1006551014112	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
1006551014113	NLPA lipoprotein; Region: Lipoprotein_9; cl17547
1006551014114	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
1006551014115	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
1006551014116	active site
1006551014117	purine riboside binding site [chemical binding]; other site
1006551014118	putative oxidoreductase; Provisional; Region: PRK11579
1006551014119	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1006551014120	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1006551014121	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1006551014122	beta-galactosidase; Region: BGL; TIGR03356
1006551014123	oriC-binding nucleoid-associated protein; Provisional; Region: PRK10391
1006551014124	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
1006551014125	electron transport complex protein RsxA; Provisional; Region: PRK05151
1006551014126	electron transport complex protein RnfB; Provisional; Region: PRK05113
1006551014127	Putative Fe-S cluster; Region: FeS; cl17515
1006551014128	4Fe-4S binding domain; Region: Fer4; pfam00037
1006551014129	Predicted NADH:ubiquinone oxidoreductase, subunit RnfC [Energy production and conversion]; Region: RnfC; COG4656
1006551014130	SLBB domain; Region: SLBB; pfam10531
1006551014131	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1006551014132	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
1006551014133	electron transport complex protein RnfG; Validated; Region: PRK01908
1006551014134	electron transport complex RsxE subunit; Provisional; Region: PRK12405
1006551014135	endonuclease III; Provisional; Region: PRK10702
1006551014136	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1006551014137	minor groove reading motif; other site
1006551014138	helix-hairpin-helix signature motif; other site
1006551014139	substrate binding pocket [chemical binding]; other site
1006551014140	active site
1006551014141	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1006551014142	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
1006551014143	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551014144	putative substrate translocation pore; other site
1006551014145	POT family; Region: PTR2; pfam00854
1006551014146	glutathionine S-transferase; Provisional; Region: PRK10542
1006551014147	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
1006551014148	C-terminal domain interface [polypeptide binding]; other site
1006551014149	GSH binding site (G-site) [chemical binding]; other site
1006551014150	dimer interface [polypeptide binding]; other site
1006551014151	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
1006551014152	N-terminal domain interface [polypeptide binding]; other site
1006551014153	dimer interface [polypeptide binding]; other site
1006551014154	substrate binding pocket (H-site) [chemical binding]; other site
1006551014155	pyridoxamine kinase; Validated; Region: PRK05756
1006551014156	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
1006551014157	dimer interface [polypeptide binding]; other site
1006551014158	pyridoxal binding site [chemical binding]; other site
1006551014159	ATP binding site [chemical binding]; other site
1006551014160	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
1006551014161	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1006551014162	active site
1006551014163	HIGH motif; other site
1006551014164	dimer interface [polypeptide binding]; other site
1006551014165	KMSKS motif; other site
1006551014166	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1006551014167	RNA binding surface [nucleotide binding]; other site
1006551014168	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
1006551014169	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
1006551014170	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
1006551014171	lysozyme inhibitor; Provisional; Region: PRK11372
1006551014172	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; pfam09864
1006551014173	anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585
1006551014174	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
1006551014175	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1006551014176	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1006551014177	metal binding site [ion binding]; metal-binding site
1006551014178	active site
1006551014179	I-site; other site
1006551014180	transcriptional regulator SlyA; Provisional; Region: PRK03573
1006551014181	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
1006551014182	Protein of unknown function (DUF1656); Region: DUF1656; pfam07869
1006551014183	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
1006551014184	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1006551014185	HlyD family secretion protein; Region: HlyD_3; pfam13437
1006551014186	Fusaric acid resistance protein family; Region: FUSC; pfam04632
1006551014187	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1006551014188	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
1006551014189	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
1006551014190	E-class dimer interface [polypeptide binding]; other site
1006551014191	P-class dimer interface [polypeptide binding]; other site
1006551014192	active site
1006551014193	Cu2+ binding site [ion binding]; other site
1006551014194	Zn2+ binding site [ion binding]; other site
1006551014195	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1006551014196	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1006551014197	active site
1006551014198	catalytic tetrad [active]
1006551014199	Protein of unknown function (DUF1289); Region: DUF1289; cl01304
1006551014200	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1006551014201	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1006551014202	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1006551014203	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
1006551014204	FMN binding site [chemical binding]; other site
1006551014205	active site
1006551014206	substrate binding site [chemical binding]; other site
1006551014207	catalytic residue [active]
1006551014208	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1006551014209	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
1006551014210	dimer interface [polypeptide binding]; other site
1006551014211	active site
1006551014212	metal binding site [ion binding]; metal-binding site
1006551014213	glutathione binding site [chemical binding]; other site
1006551014214	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
1006551014215	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
1006551014216	dimer interface [polypeptide binding]; other site
1006551014217	catalytic site [active]
1006551014218	putative active site [active]
1006551014219	putative substrate binding site [chemical binding]; other site
1006551014220	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
1006551014221	putative GSH binding site [chemical binding]; other site
1006551014222	catalytic residues [active]
1006551014223	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1006551014224	NlpC/P60 family; Region: NLPC_P60; pfam00877
1006551014225	superoxide dismutase; Provisional; Region: PRK10543
1006551014226	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1006551014227	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1006551014228	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551014229	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1006551014230	putative substrate translocation pore; other site
1006551014231	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
1006551014232	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1006551014233	DNA binding site [nucleotide binding]
1006551014234	domain linker motif; other site
1006551014235	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
1006551014236	dimerization interface [polypeptide binding]; other site
1006551014237	ligand binding site [chemical binding]; other site
1006551014238	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1006551014239	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551014240	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1006551014241	dimerization interface [polypeptide binding]; other site
1006551014242	putative transporter; Provisional; Region: PRK11043
1006551014243	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551014244	putative substrate translocation pore; other site
1006551014245	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
1006551014246	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551014247	S-adenosylmethionine binding site [chemical binding]; other site
1006551014248	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
1006551014249	Lumazine binding domain; Region: Lum_binding; pfam00677
1006551014250	Lumazine binding domain; Region: Lum_binding; pfam00677
1006551014251	multidrug efflux protein; Reviewed; Region: PRK01766
1006551014252	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
1006551014253	cation binding site [ion binding]; other site
1006551014254	General stress protein [General function prediction only]; Region: GsiB; COG3729
1006551014255	YciF bacterial stress response protein, ferritin-like iron-binding domain; Region: YciF; cd07909
1006551014256	dimerization interface [polypeptide binding]; other site
1006551014257	metal binding site [ion binding]; metal-binding site
1006551014258	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
1006551014259	dinuclear metal binding motif [ion binding]; other site
1006551014260	Manganese catalase, ferritin-like diiron-binding domain; Region: Mn_catalase; cd01051
1006551014261	dimanganese center [ion binding]; other site
1006551014262	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
1006551014263	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
1006551014264	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1006551014265	trehalose synthase; Region: treS_nterm; TIGR02456
1006551014266	Alpha amylase catalytic domain found in Trehalose synthetase; Region: AmyAc_TreS; cd11334
1006551014267	active site
1006551014268	catalytic site [active]
1006551014269	short chain dehydrogenase; Provisional; Region: PRK06181
1006551014270	classical (c) SDR, subgroup 3; Region: SDR_c3; cd05360
1006551014271	putative NAD(P) binding site [chemical binding]; other site
1006551014272	active site
1006551014273	Competence-damaged protein; Region: CinA; cl00666
1006551014274	Predicted membrane protein [Function unknown]; Region: COG2323
1006551014275	hypothetical protein; Provisional; Region: PRK09897
1006551014276	FAD-NAD(P)-binding; Region: NAD_binding_9; pfam13454
1006551014277	hypothetical protein; Provisional; Region: PRK10053
1006551014278	oxidoreductase; Provisional; Region: PRK06128
1006551014279	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
1006551014280	NAD binding site [chemical binding]; other site
1006551014281	metal binding site [ion binding]; metal-binding site
1006551014282	active site
1006551014283	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1006551014284	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeB; cd00884
1006551014285	active site clefts [active]
1006551014286	zinc binding site [ion binding]; other site
1006551014287	dimer interface [polypeptide binding]; other site
1006551014288	LysE type translocator; Region: LysE; cl00565
1006551014289	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1006551014290	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1006551014291	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1006551014292	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
1006551014293	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1006551014294	active site
1006551014295	metal binding site [ion binding]; metal-binding site
1006551014296	Chloramphenicol O-acetyltransferase [Defense mechanisms]; Region: COG4845
1006551014297	Chloramphenicol acetyltransferase; Region: CAT; cl02008
1006551014298	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1006551014299	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cd00995
1006551014300	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1006551014301	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551014302	dimer interface [polypeptide binding]; other site
1006551014303	conserved gate region; other site
1006551014304	putative PBP binding loops; other site
1006551014305	ABC-ATPase subunit interface; other site
1006551014306	nickel ABC transporter, permease subunit NikC; Region: nickel_nikC; TIGR02790
1006551014307	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551014308	dimer interface [polypeptide binding]; other site
1006551014309	conserved gate region; other site
1006551014310	putative PBP binding loops; other site
1006551014311	ABC-ATPase subunit interface; other site
1006551014312	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1006551014313	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1006551014314	Walker A/P-loop; other site
1006551014315	ATP binding site [chemical binding]; other site
1006551014316	Q-loop/lid; other site
1006551014317	ABC transporter signature motif; other site
1006551014318	Walker B; other site
1006551014319	D-loop; other site
1006551014320	H-loop/switch region; other site
1006551014321	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1006551014322	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
1006551014323	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1006551014324	Walker A/P-loop; other site
1006551014325	ATP binding site [chemical binding]; other site
1006551014326	Q-loop/lid; other site
1006551014327	ABC transporter signature motif; other site
1006551014328	Walker B; other site
1006551014329	D-loop; other site
1006551014330	H-loop/switch region; other site
1006551014331	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1006551014332	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
1006551014333	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
1006551014334	Trp docking motif [polypeptide binding]; other site
1006551014335	putative active site [active]
1006551014336	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1006551014337	active site
1006551014338	DNA binding site [nucleotide binding]
1006551014339	Int/Topo IB signature motif; other site
1006551014340	Fimbrial protein; Region: Fimbrial; cl01416
1006551014341	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1006551014342	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1006551014343	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1006551014344	PapC N-terminal domain; Region: PapC_N; pfam13954
1006551014345	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1006551014346	PapC C-terminal domain; Region: PapC_C; pfam13953
1006551014347	Fimbrial protein; Region: Fimbrial; pfam00419
1006551014348	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1006551014349	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1006551014350	active site
1006551014351	DNA binding site [nucleotide binding]
1006551014352	Int/Topo IB signature motif; other site
1006551014353	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
1006551014354	Protein of unknown function (DUF535); Region: DUF535; cl01128
1006551014355	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1006551014356	DNA-binding site [nucleotide binding]; DNA binding site
1006551014357	RNA-binding motif; other site
1006551014358	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551014359	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551014360	The C-terminal substrate binding domain of LysR-type transcrptional regulator BudR, which is responsible for activation of the expression of the butanediol operon genes; contains the type 2 periplasmic binding fold; Region: PBP2_BudR; cd08451
1006551014361	putative dimerization interface [polypeptide binding]; other site
1006551014362	putative substrate binding pocket [chemical binding]; other site
1006551014363	Alpha-acetolactate decarboxylase; Region: AAL_decarboxy; pfam03306
1006551014364	acetolactate synthase; Reviewed; Region: PRK08617
1006551014365	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1006551014366	PYR/PP interface [polypeptide binding]; other site
1006551014367	dimer interface [polypeptide binding]; other site
1006551014368	TPP binding site [chemical binding]; other site
1006551014369	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1006551014370	Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; composed of proteins similar to Klebsiella pneumoniae ALS, a catabolic enzyme required for butanediol fermentation. ALS catalyzes the conversion of 2...; Region: TPP_ALS; cd02010
1006551014371	TPP-binding site [chemical binding]; other site
1006551014372	dimer interface [polypeptide binding]; other site
1006551014373	acetoin reductase; Validated; Region: PRK08643
1006551014374	meso-2,3-butanediol dehydrogenase-like, classical (c) SDRs; Region: meso-BDH-like_SDR_c; cd05366
1006551014375	NAD binding site [chemical binding]; other site
1006551014376	homotetramer interface [polypeptide binding]; other site
1006551014377	homodimer interface [polypeptide binding]; other site
1006551014378	active site
1006551014379	substrate binding site [chemical binding]; other site
1006551014380	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
1006551014381	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551014382	Walker A/P-loop; other site
1006551014383	ATP binding site [chemical binding]; other site
1006551014384	Q-loop/lid; other site
1006551014385	ABC transporter signature motif; other site
1006551014386	Walker B; other site
1006551014387	D-loop; other site
1006551014388	H-loop/switch region; other site
1006551014389	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
1006551014390	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551014391	dimer interface [polypeptide binding]; other site
1006551014392	conserved gate region; other site
1006551014393	ABC-ATPase subunit interface; other site
1006551014394	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551014395	dimer interface [polypeptide binding]; other site
1006551014396	conserved gate region; other site
1006551014397	putative PBP binding loops; other site
1006551014398	ABC-ATPase subunit interface; other site
1006551014399	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1006551014400	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
1006551014401	Type VI secretion lipoprotein; Region: T6SS-SciN; pfam12790
1006551014402	Protein of unknown function (DUF1305); Region: DUF1305; pfam06996
1006551014403	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
1006551014404	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
1006551014405	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
1006551014406	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
1006551014407	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
1006551014408	SUR7/PalI family; Region: SUR7; pfam06687
1006551014409	Predicted ATPase involved in replication control, Cdc46/Mcm family [DNA replication, recombination, and repair]; Region: MCM2; COG1241
1006551014410	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
1006551014411	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1006551014412	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1006551014413	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
1006551014414	Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; pfam10106
1006551014415	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
1006551014416	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
1006551014417	Protein of unknown function (DUF796); Region: DUF796; cl01226
1006551014418	Protein of unknown function (DUF796); Region: DUF796; cl01226
1006551014419	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1006551014420	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1006551014421	ligand binding site [chemical binding]; other site
1006551014422	Uncharacterized protein conserved in bacteria (DUF2077); Region: DUF2077; pfam09850
1006551014423	type VI secretion protein, VC_A0114 family; Region: VI_chp_4; TIGR03353
1006551014424	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
1006551014425	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517
1006551014426	Protein of unknown function (DUF877); Region: DUF877; pfam05943
1006551014427	Protein of unknown function (DUF770); Region: DUF770; pfam05591
1006551014428	putative dehydrogenase; Provisional; Region: PRK10098
1006551014429	formate dehydrogenase, alpha subunit, archaeal-type; Region: Fdh-alpha; TIGR01591
1006551014430	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_Formate-Dh-H; cd02753
1006551014431	[4Fe-4S] binding site [ion binding]; other site
1006551014432	molybdopterin cofactor binding site; other site
1006551014433	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_CT_Formate-Dh_H; cd02790
1006551014434	molybdopterin cofactor binding site; other site
1006551014435	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1006551014436	M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_like1; cd05666
1006551014437	metal binding site [ion binding]; metal-binding site
1006551014438	putative dimer interface [polypeptide binding]; other site
1006551014439	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551014440	putative substrate translocation pore; other site
1006551014441	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1006551014442	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1006551014443	Walker A/P-loop; other site
1006551014444	ATP binding site [chemical binding]; other site
1006551014445	Q-loop/lid; other site
1006551014446	ABC transporter signature motif; other site
1006551014447	Walker B; other site
1006551014448	D-loop; other site
1006551014449	H-loop/switch region; other site
1006551014450	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1006551014451	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551014452	dimer interface [polypeptide binding]; other site
1006551014453	conserved gate region; other site
1006551014454	putative PBP binding loops; other site
1006551014455	ABC-ATPase subunit interface; other site
1006551014456	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551014457	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1006551014458	substrate binding pocket [chemical binding]; other site
1006551014459	membrane-bound complex binding site; other site
1006551014460	hinge residues; other site
1006551014461	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1006551014462	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1006551014463	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1006551014464	putative active site [active]
1006551014465	potential frameshift: common BLAST hit: gi|152970650|ref|YP_001335759.1| iron ABC transporter substrate-binding protein
1006551014466	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
1006551014467	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1006551014468	ABC-ATPase subunit  interface; other site
1006551014469	dimer interface [polypeptide binding]; other site
1006551014470	putative PBP binding regions; other site
1006551014471	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1006551014472	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1006551014473	ABC-ATPase subunit  interface; other site
1006551014474	dimer interface [polypeptide binding]; other site
1006551014475	putative PBP binding regions; other site
1006551014476	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1006551014477	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1006551014478	Walker A/P-loop; other site
1006551014479	ATP binding site [chemical binding]; other site
1006551014480	Q-loop/lid; other site
1006551014481	ABC transporter signature motif; other site
1006551014482	Walker B; other site
1006551014483	D-loop; other site
1006551014484	H-loop/switch region; other site
1006551014485	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
1006551014486	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1006551014487	N-terminal plug; other site
1006551014488	ligand-binding site [chemical binding]; other site
1006551014489	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
1006551014490	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1006551014491	Walker A/P-loop; other site
1006551014492	ATP binding site [chemical binding]; other site
1006551014493	Q-loop/lid; other site
1006551014494	ABC transporter signature motif; other site
1006551014495	Walker B; other site
1006551014496	D-loop; other site
1006551014497	H-loop/switch region; other site
1006551014498	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1006551014499	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551014500	dimer interface [polypeptide binding]; other site
1006551014501	conserved gate region; other site
1006551014502	putative PBP binding loops; other site
1006551014503	ABC-ATPase subunit interface; other site
1006551014504	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
1006551014505	NMT1/THI5 like; Region: NMT1; pfam09084
1006551014506	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551014507	membrane-bound complex binding site; other site
1006551014508	hinge residues; other site
1006551014509	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
1006551014510	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
1006551014511	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
1006551014512	alkanesulfonate monooxygenase, FMNH(2)-dependent; Region: alk_sulf_monoox; TIGR03565
1006551014513	dimer interface [polypeptide binding]; other site
1006551014514	active site
1006551014515	non-prolyl cis peptide bond; other site
1006551014516	insertion regions; other site
1006551014517	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551014518	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551014519	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1006551014520	dimerization interface [polypeptide binding]; other site
1006551014521	Predicted metal-dependent enzyme of the double-stranded beta helix superfamily [General function prediction only]; Region: COG5553
1006551014522	Member of the Rhodanese Homology Domain superfamily, repeat 1. This CD includes putative rhodanese-related sulfurtransferases which contain 4 copies of the Rhodanese Homology Domain. This CD aligns the 1st repeat which does not contain the putative...; Region: 4RHOD_Repeat_1; cd01532
1006551014523	active site residue [active]
1006551014524	Member of the Rhodanese Homology Domain superfamily, repeat 2. This CD includes putative rhodanese-related sulfurtransferases which contain 4 copies of the Rhodanese Homology Domain. This CD aligns the 2nd repeat which does contain the putative catalytic...; Region: 4RHOD_Repeat_2; cd01533
1006551014525	active site residue [active]
1006551014526	Member of the Rhodanese Homology Domain superfamily, repeat 3. This CD includes putative rhodanese-related sulfurtransferases which contain 4 copies of the Rhodanese Homology Domain. This CD aligns the 3rd repeat which does not contain the putative...; Region: 4RHOD_Repeat_3; cd01534
1006551014527	active site residue [active]
1006551014528	Member of the Rhodanese Homology Domain superfamily, repeat 4. This CD includes putative rhodanese-related sulfurtransferases which contain 4 copies of the Rhodanese Homology Domain. This CD aligns the 4th repeat which, in general, contains the putative...; Region: 4RHOD_Repeat_4; cd01535
1006551014529	active site residue [active]
1006551014530	Domain of unknown function (DUF1996); Region: DUF1996; pfam09362
1006551014531	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; pfam02578
1006551014532	putative 3-hydroxyphenylpropionic transporter MhpT; Provisional; Region: PRK11551
1006551014533	4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase,; Validated; Region: PRK08195
1006551014534	4-hydroxy-2-oxovalerate aldolase, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_HOA; cd07943
1006551014535	active site
1006551014536	catalytic residues [active]
1006551014537	metal binding site [ion binding]; metal-binding site
1006551014538	DmpG-like communication domain; Region: DmpG_comm; pfam07836
1006551014539	acetaldehyde dehydrogenase; Validated; Region: PRK08300
1006551014540	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1006551014541	Prokaryotic acetaldehyde dehydrogenase, dimerisation; Region: AcetDehyd-dimer; pfam09290
1006551014542	2-keto-4-pentenoate hydratase; Provisional; Region: mhpD; PRK11342
1006551014543	2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; Region: biphenyl_bphD; TIGR03343
1006551014544	S-formylglutathione hydrolase; Region: PLN02442
1006551014545	Subunit B of the Class III Extradiol ring-cleavage dioxygenase, 2,3-dihydroxyphenylpropionate 1,2-dioxygenase (MhpB), which catalyzes the oxidization and subsequent ring-opening of 2,3-dihydroxyphenylpropionate; Region: MhpB_like; cd07365
1006551014546	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
1006551014547	putative active site [active]
1006551014548	Fe(II) binding site [ion binding]; other site
1006551014549	putative dimer interface [polypeptide binding]; other site
1006551014550	putative tetramer interface [polypeptide binding]; other site
1006551014551	3-(3-hydroxyphenyl)propionate hydroxylase; Validated; Region: mhpA; PRK06183
1006551014552	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1006551014553	DNA-binding transcriptional activator MhpR; Provisional; Region: PRK09834
1006551014554	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1006551014555	Bacterial transcriptional regulator; Region: IclR; pfam01614
1006551014556	Periplasmic binding protein TroA_e.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_e; cd01142
1006551014557	putative ligand binding residues [chemical binding]; other site
1006551014558	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1006551014559	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
1006551014560	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1006551014561	ABC-ATPase subunit  interface; other site
1006551014562	dimer interface [polypeptide binding]; other site
1006551014563	putative PBP binding regions; other site
1006551014564	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1006551014565	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551014566	Walker A/P-loop; other site
1006551014567	ATP binding site [chemical binding]; other site
1006551014568	Q-loop/lid; other site
1006551014569	ABC transporter signature motif; other site
1006551014570	Walker B; other site
1006551014571	D-loop; other site
1006551014572	H-loop/switch region; other site
1006551014573	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1006551014574	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1006551014575	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
1006551014576	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1006551014577	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1006551014578	NAD(P) binding site [chemical binding]; other site
1006551014579	shikimate binding site; other site
1006551014580	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551014581	D-galactonate transporter; Region: 2A0114; TIGR00893
1006551014582	putative substrate translocation pore; other site
1006551014583	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1006551014584	4-hydroxyphenylpyruvate dioxygenase and related hemolysins [Amino acid transport and metabolism / General function prediction only]; Region: COG3185
1006551014585	N-terminal domain of 4-hydroxyphenylpyruvate dioxygenase (HPPD) and hydroxymandelate Synthase (HmaS); Region: HPPD_N_like; cd08342
1006551014586	dimer interface [polypeptide binding]; other site
1006551014587	C-terminal domain of 4-hydroxyphenylpyruvate dioxygenase (HppD) and hydroxymandelate Synthase (HmaS); Region: HPPD_C_like; cd07250
1006551014588	active site
1006551014589	Fe binding site [ion binding]; other site
1006551014590	HTH-type transcriptional regulator RutR; Provisional; Region: PRK15008
1006551014591	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1006551014592	hypothetical protein; Provisional; Region: PRK10292
1006551014593	pyruvate kinase; Provisional; Region: PRK09206
1006551014594	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
1006551014595	domain interfaces; other site
1006551014596	active site
1006551014597	murein lipoprotein; Provisional; Region: PRK15396
1006551014598	L,D-transpeptidase; Provisional; Region: PRK10260
1006551014599	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1006551014600	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1006551014601	cysteine desufuration protein SufE; Provisional; Region: PRK09296
1006551014602	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1006551014603	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1006551014604	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1006551014605	catalytic residue [active]
1006551014606	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
1006551014607	FeS assembly protein SufD; Region: sufD; TIGR01981
1006551014608	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
1006551014609	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
1006551014610	Walker A/P-loop; other site
1006551014611	ATP binding site [chemical binding]; other site
1006551014612	Q-loop/lid; other site
1006551014613	ABC transporter signature motif; other site
1006551014614	Walker B; other site
1006551014615	D-loop; other site
1006551014616	H-loop/switch region; other site
1006551014617	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
1006551014618	putative ABC transporter; Region: ycf24; CHL00085
1006551014619	iron-sulfur cluster assembly scaffold protein; Provisional; Region: sufA; PRK09504
1006551014620	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1006551014621	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
1006551014622	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1006551014623	PapC N-terminal domain; Region: PapC_N; pfam13954
1006551014624	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1006551014625	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1006551014626	PapC C-terminal domain; Region: PapC_C; pfam13953
1006551014627	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1006551014628	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1006551014629	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1006551014630	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1006551014631	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
1006551014632	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cl00047
1006551014633	ligand binding site [chemical binding]; other site
1006551014634	flexible hinge region; other site
1006551014635	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
1006551014636	hypothetical protein; Provisional; Region: PRK10457
1006551014637	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1006551014638	CoenzymeA binding site [chemical binding]; other site
1006551014639	subunit interaction site [polypeptide binding]; other site
1006551014640	PHB binding site; other site
1006551014641	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
1006551014642	FAD binding domain; Region: FAD_binding_4; pfam01565
1006551014643	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1006551014644	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
1006551014645	putative inner membrane protein; Provisional; Region: PRK10983
1006551014646	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1006551014647	phosphoenolpyruvate synthase; Validated; Region: PRK06464
1006551014648	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
1006551014649	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1006551014650	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1006551014651	PEP synthetase regulatory protein; Provisional; Region: PRK05339
1006551014652	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
1006551014653	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1006551014654	Hemin uptake protein hemP; Region: hemP; cl10043
1006551014655	Uncharacterized conserved protein [Function unknown]; Region: COG0397
1006551014656	hypothetical protein; Validated; Region: PRK00029
1006551014657	NlpC/P60 family; Region: NLPC_P60; pfam00877
1006551014658	vitamin B12-transporter ATPase; Provisional; Region: PRK03695
1006551014659	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1006551014660	Walker A/P-loop; other site
1006551014661	ATP binding site [chemical binding]; other site
1006551014662	Q-loop/lid; other site
1006551014663	ABC transporter signature motif; other site
1006551014664	Walker B; other site
1006551014665	D-loop; other site
1006551014666	H-loop/switch region; other site
1006551014667	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
1006551014668	catalytic residues [active]
1006551014669	dimer interface [polypeptide binding]; other site
1006551014670	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
1006551014671	NLPA lipoprotein; Region: Lipoprotein_9; cl17547
1006551014672	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1006551014673	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1006551014674	ABC-ATPase subunit  interface; other site
1006551014675	dimer interface [polypeptide binding]; other site
1006551014676	putative PBP binding regions; other site
1006551014677	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1006551014678	IHF dimer interface [polypeptide binding]; other site
1006551014679	IHF - DNA interface [nucleotide binding]; other site
1006551014680	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
1006551014681	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1006551014682	putative tRNA-binding site [nucleotide binding]; other site
1006551014683	B3/4 domain; Region: B3_4; pfam03483
1006551014684	tRNA synthetase B5 domain; Region: B5; smart00874
1006551014685	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
1006551014686	dimer interface [polypeptide binding]; other site
1006551014687	motif 1; other site
1006551014688	motif 3; other site
1006551014689	motif 2; other site
1006551014690	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
1006551014691	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1006551014692	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1006551014693	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1006551014694	dimer interface [polypeptide binding]; other site
1006551014695	motif 1; other site
1006551014696	active site
1006551014697	motif 2; other site
1006551014698	motif 3; other site
1006551014699	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1006551014700	23S rRNA binding site [nucleotide binding]; other site
1006551014701	L21 binding site [polypeptide binding]; other site
1006551014702	L13 binding site [polypeptide binding]; other site
1006551014703	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
1006551014704	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
1006551014705	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
1006551014706	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1006551014707	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
1006551014708	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
1006551014709	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
1006551014710	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1006551014711	active site
1006551014712	dimer interface [polypeptide binding]; other site
1006551014713	motif 1; other site
1006551014714	motif 2; other site
1006551014715	motif 3; other site
1006551014716	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1006551014717	anticodon binding site; other site
1006551014718	Putative salt-induced outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG3137
1006551014719	6-phosphofructokinase 2; Provisional; Region: PRK10294
1006551014720	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1006551014721	putative substrate binding site [chemical binding]; other site
1006551014722	putative ATP binding site [chemical binding]; other site
1006551014723	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
1006551014724	Phosphotransferase enzyme family; Region: APH; pfam01636
1006551014725	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
1006551014726	active site
1006551014727	ATP binding site [chemical binding]; other site
1006551014728	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1006551014729	transport protein TonB; Provisional; Region: PRK10819
1006551014730	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1006551014731	YciI-like protein; Reviewed; Region: PRK11370
1006551014732	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1006551014733	Old yellow enzyme (OYE) YqjM-like FMN binding domain. YqjM is involved in the oxidative stress response of Bacillus subtilis.  Like the other OYE members, each monomer of YqjM contains FMN as a non-covalently bound cofactor and uses NADPH as a reducing...; Region: OYE_YqiM_FMN; cd02932
1006551014734	active site
1006551014735	FMN binding site [chemical binding]; other site
1006551014736	substrate binding site [chemical binding]; other site
1006551014737	homotetramer interface [polypeptide binding]; other site
1006551014738	catalytic residue [active]
1006551014739	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
1006551014740	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
1006551014741	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
1006551014742	putative active site [active]
1006551014743	catalytic site [active]
1006551014744	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
1006551014745	putative active site [active]
1006551014746	catalytic site [active]
1006551014747	dsDNA-mimic protein; Reviewed; Region: PRK05094
1006551014748	Ion transport protein; Region: Ion_trans; pfam00520
1006551014749	Ion channel; Region: Ion_trans_2; pfam07885
1006551014750	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
1006551014751	Double zinc ribbon; Region: DZR; pfam12773
1006551014752	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
1006551014753	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1006551014754	Walker A/P-loop; other site
1006551014755	ATP binding site [chemical binding]; other site
1006551014756	Q-loop/lid; other site
1006551014757	ABC transporter signature motif; other site
1006551014758	Walker B; other site
1006551014759	D-loop; other site
1006551014760	H-loop/switch region; other site
1006551014761	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1006551014762	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
1006551014763	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1006551014764	Walker A/P-loop; other site
1006551014765	ATP binding site [chemical binding]; other site
1006551014766	Q-loop/lid; other site
1006551014767	ABC transporter signature motif; other site
1006551014768	Walker B; other site
1006551014769	D-loop; other site
1006551014770	H-loop/switch region; other site
1006551014771	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1006551014772	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
1006551014773	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1006551014774	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551014775	dimer interface [polypeptide binding]; other site
1006551014776	conserved gate region; other site
1006551014777	ABC-ATPase subunit interface; other site
1006551014778	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
1006551014779	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551014780	dimer interface [polypeptide binding]; other site
1006551014781	conserved gate region; other site
1006551014782	putative PBP binding loops; other site
1006551014783	ABC-ATPase subunit interface; other site
1006551014784	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1006551014785	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1006551014786	peptide binding site [polypeptide binding]; other site
1006551014787	hypothetical protein; Provisional; Region: PRK11111
1006551014788	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
1006551014789	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
1006551014790	putative catalytic cysteine [active]
1006551014791	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
1006551014792	putative active site [active]
1006551014793	metal binding site [ion binding]; metal-binding site
1006551014794	thymidine kinase; Provisional; Region: PRK04296
1006551014795	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
1006551014796	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
1006551014797	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1006551014798	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1006551014799	active site
1006551014800	tetramer interface; other site
1006551014801	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551014802	active site
1006551014803	response regulator of RpoS; Provisional; Region: PRK10693
1006551014804	phosphorylation site [posttranslational modification]
1006551014805	intermolecular recognition site; other site
1006551014806	dimerization interface [polypeptide binding]; other site
1006551014807	hypothetical protein; Provisional; Region: PRK10279
1006551014808	Bacterial patatin-like phospholipase domain containing protein 6; Region: Pat_NTE_like_bacteria; cd07228
1006551014809	nucleophile elbow; other site
1006551014810	SEC-C motif; Region: SEC-C; pfam02810
1006551014811	hypothetical protein; Provisional; Region: PRK04233
1006551014812	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
1006551014813	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
1006551014814	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
1006551014815	putative active site [active]
1006551014816	putative substrate binding site [chemical binding]; other site
1006551014817	putative cosubstrate binding site; other site
1006551014818	catalytic site [active]
1006551014819	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
1006551014820	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
1006551014821	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
1006551014822	4Fe-4S binding domain; Region: Fer4; cl02805
1006551014823	respiratory nitrate reductase, alpha subunit; Region: narG; TIGR01580
1006551014824	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
1006551014825	[4Fe-4S] binding site [ion binding]; other site
1006551014826	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1006551014827	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1006551014828	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1006551014829	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
1006551014830	molybdopterin cofactor binding site; other site
1006551014831	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
1006551014832	nitrate/nitrite sensor protein NarX; Provisional; Region: PRK10600
1006551014833	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
1006551014834	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1006551014835	dimerization interface [polypeptide binding]; other site
1006551014836	Histidine kinase; Region: HisKA_3; pfam07730
1006551014837	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551014838	ATP binding site [chemical binding]; other site
1006551014839	Mg2+ binding site [ion binding]; other site
1006551014840	G-X-G motif; other site
1006551014841	transcriptional regulator NarL; Provisional; Region: PRK10651
1006551014842	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551014843	active site
1006551014844	phosphorylation site [posttranslational modification]
1006551014845	intermolecular recognition site; other site
1006551014846	dimerization interface [polypeptide binding]; other site
1006551014847	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1006551014848	DNA binding residues [nucleotide binding]
1006551014849	dimerization interface [polypeptide binding]; other site
1006551014850	putative invasin; Provisional; Region: PRK10177
1006551014851	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
1006551014852	Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243
1006551014853	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
1006551014854	[4Fe-4S] binding site [ion binding]; other site
1006551014855	molybdopterin cofactor binding site; other site
1006551014856	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
1006551014857	molybdopterin cofactor binding site; other site
1006551014858	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1006551014859	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992
1006551014860	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1006551014861	nitrite reductase subunit NirD; Provisional; Region: PRK14989
1006551014862	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1006551014863	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1006551014864	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1006551014865	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
1006551014866	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
1006551014867	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1006551014868	Walker A/P-loop; other site
1006551014869	ATP binding site [chemical binding]; other site
1006551014870	Q-loop/lid; other site
1006551014871	ABC transporter signature motif; other site
1006551014872	Walker B; other site
1006551014873	D-loop; other site
1006551014874	H-loop/switch region; other site
1006551014875	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1006551014876	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551014877	dimer interface [polypeptide binding]; other site
1006551014878	conserved gate region; other site
1006551014879	putative PBP binding loops; other site
1006551014880	ABC-ATPase subunit interface; other site
1006551014881	potential frameshift: common BLAST hit: gi|152970770|ref|YP_001335879.1| nitrate transporter component; NasF
1006551014882	Nitrate and nitrite sensing; Region: NIT; pfam08376
1006551014883	ANTAR domain; Region: ANTAR; pfam03861
1006551014884	Uncharacterized conserved protein involved in intracellular sulfur reduction [Inorganic ion transport and metabolism]; Region: DsrE; COG1553
1006551014885	Domain of unknown function (DUF1883); Region: DUF1883; pfam08980
1006551014886	Uncharacterized protein involved in cation transport [Inorganic ion transport and metabolism]; Region: ChaC; COG3703
1006551014887	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
1006551014888	putative active site pocket [active]
1006551014889	dimerization interface [polypeptide binding]; other site
1006551014890	putative catalytic residue [active]
1006551014891	cation transport regulator; Reviewed; Region: chaB; PRK09582
1006551014892	calcium/sodium:proton antiporter; Provisional; Region: PRK10599
1006551014893	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1006551014894	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
1006551014895	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1006551014896	hypothetical protein; Provisional; Region: PRK10941
1006551014897	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
1006551014898	Zona pellucida-like domain; Region: Zona_pellucida; cl02523
1006551014899	Invasion gene expression up-regulator, SirB; Region: SirB; cl01184
1006551014900	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
1006551014901	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551014902	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1006551014903	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1006551014904	RF-1 domain; Region: RF-1; pfam00472
1006551014905	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
1006551014906	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
1006551014907	tRNA; other site
1006551014908	putative tRNA binding site [nucleotide binding]; other site
1006551014909	putative NADP binding site [chemical binding]; other site
1006551014910	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
1006551014911	outer membrane lipoprotein LolB; Provisional; Region: lolB; PRK00022
1006551014912	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
1006551014913	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
1006551014914	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1006551014915	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1006551014916	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
1006551014917	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1006551014918	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1006551014919	active site
1006551014920	putative transporter; Provisional; Region: PRK11660
1006551014921	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
1006551014922	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1006551014923	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
1006551014924	Helix-Turn-Helix DNA binding domain of the transcription regulators NolA and AlbR; Region: HTH_NolA-AlbR; cd04788
1006551014925	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1006551014926	DNA binding residues [nucleotide binding]
1006551014927	putative dimer interface [polypeptide binding]; other site
1006551014928	TipAS antibiotic-recognition domain; Region: TipAS; pfam07739
1006551014929	TipAS antibiotic-recognition domain; Region: TipAS; pfam07739
1006551014930	hypothetical protein; Provisional; Region: PRK10692
1006551014931	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1006551014932	putative active site [active]
1006551014933	catalytic residue [active]
1006551014934	GTP-binding protein YchF; Reviewed; Region: PRK09601
1006551014935	YchF GTPase; Region: YchF; cd01900
1006551014936	G1 box; other site
1006551014937	GTP/Mg2+ binding site [chemical binding]; other site
1006551014938	Switch I region; other site
1006551014939	G2 box; other site
1006551014940	Switch II region; other site
1006551014941	G3 box; other site
1006551014942	G4 box; other site
1006551014943	G5 box; other site
1006551014944	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1006551014945	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1006551014946	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1006551014947	active site
1006551014948	Int/Topo IB signature motif; other site
1006551014949	mobile mystery protein B; Region: mob_myst_B; TIGR02613
1006551014950	Fic/DOC family; Region: Fic; pfam02661
1006551014951	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829
1006551014952	PAS domain; Region: PAS; smart00091
1006551014953	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1006551014954	Walker A motif; other site
1006551014955	ATP binding site [chemical binding]; other site
1006551014956	Walker B motif; other site
1006551014957	arginine finger; other site
1006551014958	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1006551014959	aspartate/ornithine carbamoyltransferase family protein; Validated; Region: PRK07200
1006551014960	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1006551014961	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1006551014962	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
1006551014963	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cd00640
1006551014964	catalytic residue [active]
1006551014965	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
1006551014966	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1006551014967	peptidase; Reviewed; Region: PRK13004
1006551014968	M20 Peptidases with similarity to acetylornithine deacetylases and succinyl-diaminopimelate desuccinylases; Region: M20_ArgE_DapE_like4; cd05649
1006551014969	putative metal binding site [ion binding]; other site
1006551014970	putative dimer interface [polypeptide binding]; other site
1006551014971	phenylhydantoinase; Validated; Region: PRK08323
1006551014972	D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine...; Region: D-HYD; cd01314
1006551014973	tetramer interface [polypeptide binding]; other site
1006551014974	active site
1006551014975	carbamate kinase; Reviewed; Region: PRK12686
1006551014976	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
1006551014977	putative substrate binding site [chemical binding]; other site
1006551014978	homodimer interface [polypeptide binding]; other site
1006551014979	nucleotide binding site [chemical binding]; other site
1006551014980	nucleotide binding site [chemical binding]; other site
1006551014981	Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones]; Region: XdhC; COG1975
1006551014982	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
1006551014983	XdhC Rossmann domain; Region: XdhC_C; pfam13478
1006551014984	putative selenate reductase subunit YgfK; Provisional; Region: PRK09853
1006551014985	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1006551014986	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1006551014987	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1006551014988	putative chlorohydrolase/aminohydrolase; Validated; Region: PRK07203
1006551014989	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
1006551014990	active site
1006551014991	putative substrate binding pocket [chemical binding]; other site
1006551014992	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
1006551014993	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12809
1006551014994	4Fe-4S binding domain; Region: Fer4; pfam00037
1006551014995	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1006551014996	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1006551014997	xanthine permease; Region: pbuX; TIGR03173
1006551014998	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1006551014999	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1006551015000	molybdopterin cofactor binding site; other site
1006551015001	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_CT_Formate-Dh_H; cd02790
1006551015002	molybdopterin cofactor binding site; other site
1006551015003	GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function; Region: GT_2_like_f; cd04182
1006551015004	Ligand binding site; other site
1006551015005	metal-binding site
1006551015006	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080
1006551015007	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1006551015008	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
1006551015009	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
1006551015010	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
1006551015011	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
1006551015012	FAD binding domain in molybdopterin dehydrogenase; Region: FAD_binding_5; pfam00941
1006551015013	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
1006551015014	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551015015	putative substrate translocation pore; other site
1006551015016	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551015017	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1006551015018	active site
1006551015019	phosphorylation site [posttranslational modification]
1006551015020	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
1006551015021	active site
1006551015022	homotetramer interface [polypeptide binding]; other site
1006551015023	outer membrane lipoprotein Blc; Provisional; Region: PRK10477
1006551015024	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
1006551015025	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
1006551015026	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
1006551015027	active site
1006551015028	substrate-binding site [chemical binding]; other site
1006551015029	metal-binding site [ion binding]
1006551015030	ATP binding site [chemical binding]; other site
1006551015031	cell density-dependent motility repressor; Provisional; Region: PRK10082
1006551015032	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551015033	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1006551015034	dimerization interface [polypeptide binding]; other site
1006551015035	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1006551015036	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1006551015037	active site
1006551015038	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
1006551015039	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1006551015040	Walker A/P-loop; other site
1006551015041	ATP binding site [chemical binding]; other site
1006551015042	Q-loop/lid; other site
1006551015043	ABC transporter signature motif; other site
1006551015044	Walker B; other site
1006551015045	D-loop; other site
1006551015046	H-loop/switch region; other site
1006551015047	ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism]; Region: OpuBB; COG1174
1006551015048	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551015049	dimer interface [polypeptide binding]; other site
1006551015050	conserved gate region; other site
1006551015051	ABC-ATPase subunit interface; other site
1006551015052	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
1006551015053	ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; cl17891
1006551015054	nitrilotriacetate monoxygenase oxidizes nitrilotriacetate utilizing reduced flavin mononucleotide (FMNH2) and oxygen. The FMNH2 is provided by an NADH:flavin mononucleotide (FMN) oxidorductase that uses NADH to reduce FMN to FMNH2; Region: Nitrilotriacetate_monoxgenase; cd01095
1006551015055	active site
1006551015056	FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family; Region: FMN_nitrolo; TIGR03860
1006551015057	non-prolyl cis peptide bond; other site
1006551015058	ABC-type phosphate/phosphonate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PhnD; COG3221
1006551015059	Fatty acid desaturase protein family subgroup, a delta-12 acyl-lipid desaturase-like, DesA-like, yet uncharacterized subgroup of membrane fatty acid desaturase proteins found in alpha-, beta-, and gamma-proteobacteria. Sequences of this domain family...; Region: DesA_FADS-like; cd03509
1006551015060	Fatty acid desaturase; Region: FA_desaturase; pfam00487
1006551015061	putative di-iron ligands [ion binding]; other site
1006551015062	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
1006551015063	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551015064	putative substrate translocation pore; other site
1006551015065	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551015066	Helix-turn-helix domain; Region: HTH_18; pfam12833
1006551015067	Predicted proteasome-type protease [Posttranslational modification, protein turnover, chaperones]; Region: COG3484
1006551015068	Bacterial proteasome, beta subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that...; Region: proteasome_beta_bacterial; cd03765
1006551015069	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
1006551015070	Bacterial transglutaminase-like N-terminal region; Region: Bact_transglu_N; pfam08379
1006551015071	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
1006551015072	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2307
1006551015073	A predicted alpha-helical domain with a conserved ER motif; Region: Alpha-E; pfam04168
1006551015074	Uncharacterized conserved protein [Function unknown]; Region: COG2308
1006551015075	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1006551015076	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1006551015077	Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915
1006551015078	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1006551015079	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1006551015080	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1006551015081	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
1006551015082	putative symporter YagG; Provisional; Region: PRK09669
1006551015083	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551015084	putative substrate translocation pore; other site
1006551015085	Trehalase; Region: Trehalase; cl17346
1006551015086	Neutral trehalase [Carbohydrate transport and metabolism]; Region: TreA; COG1626
1006551015087	lytic murein endotransglycosylase E; Provisional; Region: emtA; PRK15470
1006551015088	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1006551015089	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1006551015090	catalytic residue [active]
1006551015091	DEP domain, named after Dishevelled, Egl-10, and Pleckstrin, where this domain was first discovered. The function of this domain is still not clear, but it is believed to be important for the membrane association of the signaling proteins in which it is...; Region: DEP; cl02442
1006551015092	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
1006551015093	dimer interface [polypeptide binding]; other site
1006551015094	catalytic triad [active]
1006551015095	NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain [Inorganic ion transport and metabolism]; Region: COG3263
1006551015096	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
1006551015097	TrkA-C domain; Region: TrkA_C; pfam02080
1006551015098	Transporter associated domain; Region: CorC_HlyC; smart01091
1006551015099	alanine racemase; Reviewed; Region: dadX; PRK03646
1006551015100	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
1006551015101	active site
1006551015102	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1006551015103	substrate binding site [chemical binding]; other site
1006551015104	catalytic residues [active]
1006551015105	dimer interface [polypeptide binding]; other site
1006551015106	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
1006551015107	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1006551015108	SpoVR family protein; Provisional; Region: PRK11767
1006551015109	Uncharacterized conserved protein [Function unknown]; Region: SpoVR; COG2719
1006551015110	fatty acid metabolism regulator; Provisional; Region: PRK04984
1006551015111	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551015112	DNA-binding site [nucleotide binding]; DNA binding site
1006551015113	FadR C-terminal domain; Region: FadR_C; pfam07840
1006551015114	sodium/proton antiporter; Reviewed; Region: nhaB; PRK09547
1006551015115	disulfide bond formation protein B; Provisional; Region: PRK01749
1006551015116	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
1006551015117	hypothetical protein; Provisional; Region: PRK05170
1006551015118	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1006551015119	hypothetical protein; Provisional; Region: PRK10691
1006551015120	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3100
1006551015121	septum formation inhibitor; Reviewed; Region: minC; PRK03511
1006551015122	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
1006551015123	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
1006551015124	cell division inhibitor MinD; Provisional; Region: PRK10818
1006551015125	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
1006551015126	Switch I; other site
1006551015127	Switch II; other site
1006551015128	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
1006551015129	ribonuclease D; Provisional; Region: PRK10829
1006551015130	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
1006551015131	catalytic site [active]
1006551015132	putative active site [active]
1006551015133	putative substrate binding site [chemical binding]; other site
1006551015134	HRDC domain; Region: HRDC; cl02578
1006551015135	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
1006551015136	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1006551015137	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
1006551015138	acyl-activating enzyme (AAE) consensus motif; other site
1006551015139	putative AMP binding site [chemical binding]; other site
1006551015140	putative active site [active]
1006551015141	putative CoA binding site [chemical binding]; other site
1006551015142	Outer membrane lipoprotein Slp family; Region: Slp; cl01164
1006551015143	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
1006551015144	Glycoprotease family; Region: Peptidase_M22; pfam00814
1006551015145	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
1006551015146	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1006551015147	DEAD_2; Region: DEAD_2; pfam06733
1006551015148	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1006551015149	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
1006551015150	homotrimer interaction site [polypeptide binding]; other site
1006551015151	putative active site [active]
1006551015152	Alginate lyase; Region: Alginate_lyase; pfam05426
1006551015153	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
1006551015154	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1006551015155	Walker A/P-loop; other site
1006551015156	ATP binding site [chemical binding]; other site
1006551015157	Q-loop/lid; other site
1006551015158	ABC transporter signature motif; other site
1006551015159	Walker B; other site
1006551015160	D-loop; other site
1006551015161	H-loop/switch region; other site
1006551015162	TOBE domain; Region: TOBE_2; pfam08402
1006551015163	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1006551015164	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551015165	dimer interface [polypeptide binding]; other site
1006551015166	conserved gate region; other site
1006551015167	putative PBP binding loops; other site
1006551015168	ABC-ATPase subunit interface; other site
1006551015169	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1006551015170	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551015171	dimer interface [polypeptide binding]; other site
1006551015172	conserved gate region; other site
1006551015173	putative PBP binding loops; other site
1006551015174	ABC-ATPase subunit interface; other site
1006551015175	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1006551015176	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1006551015177	Alginate lyase; Region: Alginate_lyase; pfam05426
1006551015178	Heparinase II/III-like protein; Region: Hepar_II_III; pfam07940
1006551015179	hypothetical protein; Provisional; Region: PRK05114
1006551015180	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
1006551015181	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1006551015182	chorismate binding enzyme; Region: Chorismate_bind; cl10555
1006551015183	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
1006551015184	putative active site [active]
1006551015185	putative CoA binding site [chemical binding]; other site
1006551015186	nudix motif; other site
1006551015187	metal binding site [ion binding]; metal-binding site
1006551015188	L-serine deaminase; Provisional; Region: PRK15023
1006551015189	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1006551015190	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1006551015191	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
1006551015192	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1006551015193	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1006551015194	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1006551015195	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1006551015196	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1006551015197	Transporter associated domain; Region: CorC_HlyC; smart01091
1006551015198	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
1006551015199	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1006551015200	active pocket/dimerization site; other site
1006551015201	active site
1006551015202	phosphorylation site [posttranslational modification]
1006551015203	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1006551015204	active site
1006551015205	phosphorylation site [posttranslational modification]
1006551015206	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
1006551015207	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
1006551015208	hypothetical protein; Provisional; Region: PRK02913
1006551015209	hypothetical protein; Provisional; Region: PRK11469
1006551015210	Domain of unknown function DUF; Region: DUF204; pfam02659
1006551015211	Domain of unknown function DUF; Region: DUF204; pfam02659
1006551015212	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
1006551015213	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551015214	S-adenosylmethionine binding site [chemical binding]; other site
1006551015215	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
1006551015216	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1006551015217	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1006551015218	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1006551015219	DNA-binding site [nucleotide binding]; DNA binding site
1006551015220	RNA-binding motif; other site
1006551015221	YebO-like protein; Region: YebO; pfam13974
1006551015222	PhoPQ regulatory protein; Provisional; Region: PRK10299
1006551015223	YobH-like protein; Region: YobH; pfam13996
1006551015224	DNA-binding transcriptional regulator KdgR; Provisional; Region: PRK15090
1006551015225	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1006551015226	dimerization interface [polypeptide binding]; other site
1006551015227	putative Zn2+ binding site [ion binding]; other site
1006551015228	putative DNA binding site [nucleotide binding]; other site
1006551015229	Bacterial transcriptional regulator; Region: IclR; pfam01614
1006551015230	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551015231	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1006551015232	putative substrate translocation pore; other site
1006551015233	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551015234	heat shock protein HtpX; Provisional; Region: PRK05457
1006551015235	carboxy-terminal protease; Provisional; Region: PRK11186
1006551015236	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1006551015237	protein binding site [polypeptide binding]; other site
1006551015238	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1006551015239	Catalytic dyad [active]
1006551015240	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
1006551015241	ProP expression regulator; Provisional; Region: PRK04950
1006551015242	ProQ/FINO family; Region: ProQ; pfam04352
1006551015243	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
1006551015244	GAF domain; Region: GAF_2; pfam13185
1006551015245	integral membrane protein, PqiA family; Region: pqiA_fam; TIGR00155
1006551015246	Paraquat-inducible protein A; Region: PqiA; pfam04403
1006551015247	Paraquat-inducible protein A; Region: PqiA; pfam04403
1006551015248	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
1006551015249	mce related protein; Region: MCE; pfam02470
1006551015250	mce related protein; Region: MCE; pfam02470
1006551015251	mce related protein; Region: MCE; pfam02470
1006551015252	mce related protein; Region: MCE; pfam02470
1006551015253	mce related protein; Region: MCE; pfam02470
1006551015254	mce related protein; Region: MCE; pfam02470
1006551015255	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
1006551015256	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551015257	S-adenosylmethionine binding site [chemical binding]; other site
1006551015258	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
1006551015259	Protein of unknown function (DUF1480); Region: DUF1480; pfam07351
1006551015260	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
1006551015261	serine/threonine protein phosphatase 1; Provisional; Region: pphA; PRK11439
1006551015262	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1006551015263	Protein of unknown function (DUF535); Region: DUF535; pfam04393
1006551015264	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
1006551015265	Spore Coat Protein U domain; Region: SCPU; pfam05229
1006551015266	Spore Coat Protein U domain; Region: SCPU; pfam05229
1006551015267	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1006551015268	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1006551015269	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1006551015270	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1006551015271	PapC C-terminal domain; Region: PapC_C; pfam13953
1006551015272	Spore Coat Protein U domain; Region: SCPU; pfam05229
1006551015273	Spore Coat Protein U domain; Region: SCPU; pfam05229
1006551015274	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
1006551015275	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
1006551015276	CopC domain; Region: CopC; cl01012
1006551015277	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
1006551015278	exodeoxyribonuclease X; Provisional; Region: PRK07983
1006551015279	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1006551015280	active site
1006551015281	catalytic site [active]
1006551015282	substrate binding site [chemical binding]; other site
1006551015283	protease 2; Provisional; Region: PRK10115
1006551015284	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1006551015285	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2979
1006551015286	tellurium resistance terB-like protein, subgroup 3; Region: terB_like_YebE; cd07178
1006551015287	putative metal binding site [ion binding]; other site
1006551015288	YebG protein; Region: YebG; pfam07130
1006551015289	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
1006551015290	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1006551015291	ATP-grasp domain; Region: ATP-grasp; pfam02222
1006551015292	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
1006551015293	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1006551015294	active site
1006551015295	intersubunit interface [polypeptide binding]; other site
1006551015296	catalytic residue [active]
1006551015297	phosphogluconate dehydratase; Validated; Region: PRK09054
1006551015298	6-phosphogluconate dehydratase; Region: edd; TIGR01196
1006551015299	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
1006551015300	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
1006551015301	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
1006551015302	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
1006551015303	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1006551015304	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1006551015305	putative active site [active]
1006551015306	pyruvate kinase; Provisional; Region: PRK05826
1006551015307	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
1006551015308	domain interfaces; other site
1006551015309	active site
1006551015310	2-hydroxycarboxylate transporter family; Region: 2HCT; pfam03390
1006551015311	Predicted permeases [General function prediction only]; Region: COG0679
1006551015312	malate dehydrogenase; Provisional; Region: PRK13529
1006551015313	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1006551015314	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
1006551015315	NAD(P) binding site [chemical binding]; other site
1006551015316	DNA-binding transcriptional activator DcuR; Provisional; Region: PRK10430
1006551015317	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551015318	active site
1006551015319	phosphorylation site [posttranslational modification]
1006551015320	intermolecular recognition site; other site
1006551015321	dimerization interface [polypeptide binding]; other site
1006551015322	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1006551015323	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1006551015324	putative acyl-acceptor binding pocket; other site
1006551015325	putative peptidase; Provisional; Region: PRK11649
1006551015326	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
1006551015327	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1006551015328	Peptidase family M23; Region: Peptidase_M23; pfam01551
1006551015329	high-affinity zinc transporter periplasmic component; Reviewed; Region: znuA; PRK09545
1006551015330	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
1006551015331	metal binding site [ion binding]; metal-binding site
1006551015332	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
1006551015333	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1006551015334	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1006551015335	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1006551015336	ABC-ATPase subunit  interface; other site
1006551015337	dimer interface [polypeptide binding]; other site
1006551015338	putative PBP binding regions; other site
1006551015339	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
1006551015340	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1006551015341	Walker A motif; other site
1006551015342	ATP binding site [chemical binding]; other site
1006551015343	Walker B motif; other site
1006551015344	arginine finger; other site
1006551015345	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1006551015346	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
1006551015347	RuvA N terminal domain; Region: RuvA_N; pfam01330
1006551015348	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
1006551015349	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
1006551015350	active site
1006551015351	putative DNA-binding cleft [nucleotide binding]; other site
1006551015352	dimer interface [polypeptide binding]; other site
1006551015353	hypothetical protein; Validated; Region: PRK00110
1006551015354	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
1006551015355	nudix motif; other site
1006551015356	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1006551015357	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1006551015358	dimer interface [polypeptide binding]; other site
1006551015359	anticodon binding site; other site
1006551015360	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1006551015361	homodimer interface [polypeptide binding]; other site
1006551015362	motif 1; other site
1006551015363	active site
1006551015364	motif 2; other site
1006551015365	GAD domain; Region: GAD; pfam02938
1006551015366	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1006551015367	active site
1006551015368	motif 3; other site
1006551015369	Isochorismatase family; Region: Isochorismatase; pfam00857
1006551015370	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1006551015371	catalytic triad [active]
1006551015372	conserved cis-peptide bond; other site
1006551015373	hypothetical protein; Provisional; Region: PRK10302
1006551015374	Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788
1006551015375	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551015376	S-adenosylmethionine binding site [chemical binding]; other site
1006551015377	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1006551015378	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551015379	S-adenosylmethionine binding site [chemical binding]; other site
1006551015380	copper homeostasis protein CutC; Provisional; Region: PRK11572
1006551015381	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
1006551015382	putative metal binding site [ion binding]; other site
1006551015383	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
1006551015384	arginyl-tRNA synthetase; Region: argS; TIGR00456
1006551015385	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
1006551015386	active site
1006551015387	HIGH motif; other site
1006551015388	KMSK motif region; other site
1006551015389	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
1006551015390	tRNA binding surface [nucleotide binding]; other site
1006551015391	anticodon binding site; other site
1006551015392	Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins [General function prediction only]; Region: COG4225
1006551015393	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1006551015394	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551015395	putative substrate translocation pore; other site
1006551015396	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1006551015397	Ligand Binding Site [chemical binding]; other site
1006551015398	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
1006551015399	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
1006551015400	active site
1006551015401	homotetramer interface [polypeptide binding]; other site
1006551015402	Trehalose-6-phosphatase [Carbohydrate transport and metabolism]; Region: OtsB; COG1877
1006551015403	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1006551015404	active site
1006551015405	motif I; other site
1006551015406	motif II; other site
1006551015407	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1006551015408	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1006551015409	TM-ABC transporter signature motif; other site
1006551015410	L-arabinose transporter ATP-binding protein; Provisional; Region: araG; PRK11288
1006551015411	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1006551015412	Walker A/P-loop; other site
1006551015413	ATP binding site [chemical binding]; other site
1006551015414	Q-loop/lid; other site
1006551015415	ABC transporter signature motif; other site
1006551015416	Walker B; other site
1006551015417	D-loop; other site
1006551015418	H-loop/switch region; other site
1006551015419	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1006551015420	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
1006551015421	Periplasmic L-arabinose-binding protein (ABP), a member of a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein superfamily; Region: PBP1_arabinose_binding; cd01540
1006551015422	ligand binding site [chemical binding]; other site
1006551015423	DJ-1 family protein; Region: not_thiJ; TIGR01383
1006551015424	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
1006551015425	conserved cys residue [active]
1006551015426	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
1006551015427	Ferritin-like domain; Region: Ferritin; pfam00210
1006551015428	ferroxidase diiron center [ion binding]; other site
1006551015429	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1006551015430	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551015431	Protein of unknown function (DUF2766); Region: DUF2766; pfam10964
1006551015432	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551015433	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1006551015434	putative substrate translocation pore; other site
1006551015435	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551015436	hypothetical protein; Provisional; Region: PRK09273
1006551015437	Ribose 5-phosphate isomerase RpiB [Carbohydrate transport and metabolism]; Region: RpiB; COG0698
1006551015438	Ribose-5-phosphate isomerase; Region: DUF3666; pfam12408
1006551015439	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
1006551015440	Ferritin-like domain; Region: Ferritin; pfam00210
1006551015441	ferroxidase diiron center [ion binding]; other site
1006551015442	probable metal-binding protein; Region: matur_matur; TIGR03853
1006551015443	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
1006551015444	aromatic amino acid transport protein; Region: araaP; TIGR00837
1006551015445	hypothetical protein; Provisional; Region: PRK10396
1006551015446	yecA family protein; Region: ygfB_yecA; TIGR02292
1006551015447	SEC-C motif; Region: SEC-C; pfam02810
1006551015448	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1006551015449	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
1006551015450	inhibitor site; inhibition site
1006551015451	active site
1006551015452	dimer interface [polypeptide binding]; other site
1006551015453	catalytic residue [active]
1006551015454	potential protein location (hypothetical protein KOX_24095 [Klebsiella oxytoca KCTC 1686]) that overlaps RNA (tRNA-L)
1006551015455	phosphatidylglycerophosphate synthetase; Provisional; Region: PRK10832
1006551015456	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
1006551015457	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1006551015458	GIY-YIG motif/motif A; other site
1006551015459	active site
1006551015460	catalytic site [active]
1006551015461	putative DNA binding site [nucleotide binding]; other site
1006551015462	metal binding site [ion binding]; metal-binding site
1006551015463	UvrB/uvrC motif; Region: UVR; pfam02151
1006551015464	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1006551015465	response regulator; Provisional; Region: PRK09483
1006551015466	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551015467	active site
1006551015468	phosphorylation site [posttranslational modification]
1006551015469	intermolecular recognition site; other site
1006551015470	dimerization interface [polypeptide binding]; other site
1006551015471	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1006551015472	DNA binding residues [nucleotide binding]
1006551015473	dimerization interface [polypeptide binding]; other site
1006551015474	hypothetical protein; Provisional; Region: PRK10613
1006551015475	DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188
1006551015476	Autoinducer binding domain; Region: Autoind_bind; pfam03472
1006551015477	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1006551015478	DNA binding residues [nucleotide binding]
1006551015479	dimerization interface [polypeptide binding]; other site
1006551015480	putative amino-acid ABC transporter ATP-binding protein YecC; Provisional; Region: PRK11264
1006551015481	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1006551015482	Walker A/P-loop; other site
1006551015483	ATP binding site [chemical binding]; other site
1006551015484	Q-loop/lid; other site
1006551015485	ABC transporter signature motif; other site
1006551015486	Walker B; other site
1006551015487	D-loop; other site
1006551015488	H-loop/switch region; other site
1006551015489	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1006551015490	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551015491	dimer interface [polypeptide binding]; other site
1006551015492	conserved gate region; other site
1006551015493	putative PBP binding loops; other site
1006551015494	ABC-ATPase subunit interface; other site
1006551015495	D-cysteine desulfhydrase; Validated; Region: PRK03910
1006551015496	Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia; Region: ACCD; cd06449
1006551015497	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551015498	catalytic residue [active]
1006551015499	cystine transporter subunit; Provisional; Region: PRK11260
1006551015500	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551015501	substrate binding pocket [chemical binding]; other site
1006551015502	membrane-bound complex binding site; other site
1006551015503	hinge residues; other site
1006551015504	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
1006551015505	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
1006551015506	active site
1006551015507	Na/Ca binding site [ion binding]; other site
1006551015508	catalytic site [active]
1006551015509	lipoprotein; Provisional; Region: PRK10397
1006551015510	colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411
1006551015511	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1006551015512	DNA binding residues [nucleotide binding]
1006551015513	dimerization interface [polypeptide binding]; other site
1006551015514	hypothetical protein; Provisional; Region: PRK10708
1006551015515	Protein of unknown function (DUF2525); Region: DUF2525; pfam10733
1006551015516	putative diguanylate cyclase YedQ; Provisional; Region: PRK15426
1006551015517	Sortases are cysteine transpeptidases, found in gram-positive bacteria, that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. They do so by catalyzing a transpeptidation reaction in which the surface protein substrate is...; Region: Sortase; cl09098
1006551015518	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1006551015519	metal binding site [ion binding]; metal-binding site
1006551015520	active site
1006551015521	I-site; other site
1006551015522	Uncharacterized small protein (DUF2158); Region: DUF2158; cl02293
1006551015523	hypothetical protein; Provisional; Region: PRK10062
1006551015524	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
1006551015525	EamA-like transporter family; Region: EamA; pfam00892
1006551015526	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
1006551015527	additional DNA contacts [nucleotide binding]; other site
1006551015528	mismatch recognition site; other site
1006551015529	active site
1006551015530	zinc binding site [ion binding]; other site
1006551015531	DNA intercalation site [nucleotide binding]; other site
1006551015532	DNA cytosine methylase; Provisional; Region: PRK10458
1006551015533	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1006551015534	cofactor binding site; other site
1006551015535	DNA binding site [nucleotide binding]
1006551015536	substrate interaction site [chemical binding]; other site
1006551015537	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
1006551015538	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1006551015539	Zn2+ binding site [ion binding]; other site
1006551015540	Mg2+ binding site [ion binding]; other site
1006551015541	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
1006551015542	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1006551015543	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1006551015544	trimer interface [polypeptide binding]; other site
1006551015545	eyelet of channel; other site
1006551015546	Predicted membrane protein [Function unknown]; Region: COG2246
1006551015547	GtrA-like protein; Region: GtrA; pfam04138
1006551015548	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
1006551015549	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1006551015550	Ligand binding site; other site
1006551015551	Putative Catalytic site; other site
1006551015552	DXD motif; other site
1006551015553	DgsA anti-repressor MtfA; Provisional; Region: PRK15410
1006551015554	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1006551015555	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
1006551015556	NAD(P) binding site [chemical binding]; other site
1006551015557	YjgH belongs to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgH_like; cd02198
1006551015558	homotrimer interaction site [polypeptide binding]; other site
1006551015559	putative active site [active]
1006551015560	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551015561	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551015562	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
1006551015563	putative effector binding pocket; other site
1006551015564	putative dimerization interface [polypeptide binding]; other site
1006551015565	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551015566	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551015567	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
1006551015568	putative effector binding pocket; other site
1006551015569	putative dimerization interface [polypeptide binding]; other site
1006551015570	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
1006551015571	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1006551015572	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
1006551015573	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
1006551015574	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1006551015575	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1006551015576	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1006551015577	motif I; other site
1006551015578	motif II; other site
1006551015579	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1006551015580	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1006551015581	Ligand Binding Site [chemical binding]; other site
1006551015582	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1006551015583	HlyD family secretion protein; Region: HlyD_3; pfam13437
1006551015584	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1006551015585	Protein export membrane protein; Region: SecD_SecF; cl14618
1006551015586	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
1006551015587	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
1006551015588	Uncharacterized membrane protein [Function unknown]; Region: SpmB; cl17667
1006551015589	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
1006551015590	Polymyxin resistance protein PmrD; Region: PmrD; cl12732
1006551015591	AMP nucleosidase; Provisional; Region: PRK08292
1006551015592	Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423
1006551015593	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
1006551015594	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c_3; pfam13589
1006551015595	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1006551015596	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551015597	ATP binding site [chemical binding]; other site
1006551015598	Mg2+ binding site [ion binding]; other site
1006551015599	G-X-G motif; other site
1006551015600	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1006551015601	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
1006551015602	cofactor binding site; other site
1006551015603	DNA binding site [nucleotide binding]
1006551015604	substrate interaction site [chemical binding]; other site
1006551015605	Domain of unknown function (DUF4102); Region: DUF4102; pfam13356
1006551015606	MATE family multidrug exporter; Provisional; Region: PRK10189
1006551015607	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
1006551015608	integrase; Provisional; Region: PRK09692
1006551015609	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1006551015610	active site
1006551015611	Int/Topo IB signature motif; other site
1006551015612	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1006551015613	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1006551015614	Helix-turn-helix domain; Region: HTH_18; pfam12833
1006551015615	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551015616	Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807
1006551015617	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551015618	putative substrate translocation pore; other site
1006551015619	Nitroreductase-like family 4.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_4; cd02140
1006551015620	dimer interface [polypeptide binding]; other site
1006551015621	FMN binding site [chemical binding]; other site
1006551015622	Uncharacterized conserved protein [Function unknown]; Region: COG2353
1006551015623	Predicted transcriptional regulators [Transcription]; Region: COG1733
1006551015624	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1006551015625	dimerization interface [polypeptide binding]; other site
1006551015626	putative DNA binding site [nucleotide binding]; other site
1006551015627	putative Zn2+ binding site [ion binding]; other site
1006551015628	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
1006551015629	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1006551015630	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1006551015631	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1006551015632	active site
1006551015633	catalytic tetrad [active]
1006551015634	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551015635	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551015636	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1006551015637	dimerization interface [polypeptide binding]; other site
1006551015638	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551015639	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551015640	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
1006551015641	putative effector binding pocket; other site
1006551015642	putative dimerization interface [polypeptide binding]; other site
1006551015643	hypothetical protein; Provisional; Region: PRK08204
1006551015644	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1006551015645	active site
1006551015646	Protein of unknown function, DUF606; Region: DUF606; pfam04657
1006551015647	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
1006551015648	phenylcoumaran benzylic ether reductase (PCBER) like, atypical (a) SDRs; Region: PCBER_SDR_a; cd05259
1006551015649	NmrA-like family; Region: NmrA; pfam05368
1006551015650	NAD(P) binding site [chemical binding]; other site
1006551015651	active site lysine
1006551015652	Predicted transcriptional regulators [Transcription]; Region: COG1733
1006551015653	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1006551015654	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1006551015655	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1006551015656	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551015657	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551015658	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1006551015659	putative effector binding pocket; other site
1006551015660	dimerization interface [polypeptide binding]; other site
1006551015661	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1006551015662	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
1006551015663	tetramerization interface [polypeptide binding]; other site
1006551015664	NAD(P) binding site [chemical binding]; other site
1006551015665	catalytic residues [active]
1006551015666	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
1006551015667	putative NAD(P)H quinone oxidoreductase, PIG3 family; Region: quinone_pig3; TIGR02824
1006551015668	PIG3 p53-inducible quinone oxidoreductase; Region: p53_inducible_oxidoreductase; cd05276
1006551015669	NAD(P) binding site [chemical binding]; other site
1006551015670	Flavin Reductases; Region: FlaRed; cl00801
1006551015671	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551015672	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551015673	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1006551015674	dimerization interface [polypeptide binding]; other site
1006551015675	Cupin domain; Region: Cupin_2; cl17218
1006551015676	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
1006551015677	intracellular protease, PfpI family; Region: PfpI; TIGR01382
1006551015678	proposed catalytic triad [active]
1006551015679	conserved cys residue [active]
1006551015680	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
1006551015681	Catalytic domain of Helicobacter pylori peptidoglycan deacetylase (HpPgdA) and similar proteins; Region: CE4_HpPgdA_like; cd10938
1006551015682	active site
1006551015683	catalytic site [active]
1006551015684	Zn binding site [ion binding]; other site
1006551015685	tetramer interface [polypeptide binding]; other site
1006551015686	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1006551015687	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551015688	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551015689	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1006551015690	dimerization interface [polypeptide binding]; other site
1006551015691	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551015692	transcriptional activator TtdR; Provisional; Region: PRK09801
1006551015693	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1006551015694	putative effector binding pocket; other site
1006551015695	dimerization interface [polypeptide binding]; other site
1006551015696	Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Escherichia coli Hsp31 protein; Region: GATase1_Hsp31_like; cd03141
1006551015697	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
1006551015698	potential catalytic triad [active]
1006551015699	conserved cys residue [active]
1006551015700	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1006551015701	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551015702	putative substrate translocation pore; other site
1006551015703	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
1006551015704	Protein of unknown function (DUF2857); Region: DUF2857; pfam11198
1006551015705	phage/conjugal plasmid C-4 type zinc finger protein, TraR family; Region: C4_traR_proteo; TIGR02419
1006551015706	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1006551015707	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1006551015708	catalytic residue [active]
1006551015709	TrbC/VIRB2 family; Region: TrbC; pfam04956
1006551015710	Type IV secretory pathway, VirB3-like protein; Region: VirB3; cl01501
1006551015711	type IV secretion/conjugal transfer ATPase, VirB4 family; Region: VirB4_CagE; TIGR00929
1006551015712	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
1006551015713	TraM recognition site of TraD and TraG; Region: TraG-D_C; cl17375
1006551015714	P-type DNA transfer protein VirB5; Region: VirB5; TIGR02791
1006551015715	Type IV secretion system proteins; Region: T4SS; pfam07996
1006551015716	TrbL/VirB6 plasmid conjugal transfer protein; Region: TrbL; pfam04610
1006551015717	VirB8 protein; Region: VirB8; pfam04335
1006551015718	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911
1006551015719	VirB7 interaction site; other site
1006551015720	Bacterial conjugation TrbI-like protein; Region: TrbI; pfam03743
1006551015721	P-type DNA transfer ATPase VirB11; Region: VirB11; TIGR02788
1006551015722	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
1006551015723	Walker A motif; other site
1006551015724	hexamer interface [polypeptide binding]; other site
1006551015725	ATP binding site [chemical binding]; other site
1006551015726	Walker B motif; other site
1006551015727	conjugal transfer protein TrbM; Provisional; Region: PRK13893
1006551015728	Dynein, heavy chain [Cytoskeleton]; Region: DYN1; COG5245
1006551015729	TraM recognition site of TraD and TraG; Region: TraG-D_C; cl17375
1006551015730	Antirestriction protein [DNA replication, recombination, and repair]; Region: COG4227
1006551015731	Domain of unknown function (DUF1738); Region: DUF1738; pfam08401
1006551015732	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551015733	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551015734	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_6; cd08475
1006551015735	putative effector binding pocket; other site
1006551015736	putative dimerization interface [polypeptide binding]; other site
1006551015737	Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR7; cd08276
1006551015738	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
1006551015739	putative NAD(P) binding site [chemical binding]; other site
1006551015740	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1006551015741	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
1006551015742	tetramer interface [polypeptide binding]; other site
1006551015743	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551015744	catalytic residue [active]
1006551015745	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1006551015746	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1006551015747	ATP binding site [chemical binding]; other site
1006551015748	putative Mg++ binding site [ion binding]; other site
1006551015749	nucleotide binding region [chemical binding]; other site
1006551015750	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1006551015751	ATP-binding site [chemical binding]; other site
1006551015752	PemK-like protein; Region: PemK; cl00995
1006551015753	Antidote-toxin recognition MazE; Region: Antitoxin-MazE; cl00877
1006551015754	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551015755	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551015756	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
1006551015757	putative effector binding pocket; other site
1006551015758	putative dimerization interface [polypeptide binding]; other site
1006551015759	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1006551015760	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1006551015761	active site
1006551015762	catalytic tetrad [active]
1006551015763	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1006551015764	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551015765	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
1006551015766	dimerization interface [polypeptide binding]; other site
1006551015767	substrate binding pocket [chemical binding]; other site
1006551015768	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
1006551015769	C-terminal domain interface [polypeptide binding]; other site
1006551015770	GSH binding site (G-site) [chemical binding]; other site
1006551015771	maleylacetoacetate isomerase; Region: maiA; TIGR01262
1006551015772	dimer interface [polypeptide binding]; other site
1006551015773	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776
1006551015774	N-terminal domain interface [polypeptide binding]; other site
1006551015775	dimer interface [polypeptide binding]; other site
1006551015776	substrate binding pocket (H-site) [chemical binding]; other site
1006551015777	L,D-transpeptidase; Provisional; Region: PRK10190
1006551015778	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1006551015779	transcriptional regulator Cbl; Reviewed; Region: cbl; PRK12679
1006551015780	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1006551015781	dimerization interface [polypeptide binding]; other site
1006551015782	nitrogen assimilation transcriptional regulator; Provisional; Region: PRK11233
1006551015783	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551015784	The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433
1006551015785	putative dimerization interface [polypeptide binding]; other site
1006551015786	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
1006551015787	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1006551015788	DNA binding site [nucleotide binding]
1006551015789	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1006551015790	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1006551015791	DNA binding residues [nucleotide binding]
1006551015792	dimerization interface [polypeptide binding]; other site
1006551015793	Fimbrial protein; Region: Fimbrial; cl01416
1006551015794	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1006551015795	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1006551015796	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1006551015797	outer membrane usher protein; Provisional; Region: PRK15193
1006551015798	PapC N-terminal domain; Region: PapC_N; pfam13954
1006551015799	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1006551015800	PapC C-terminal domain; Region: PapC_C; pfam13953
1006551015801	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1006551015802	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1006551015803	Mannose binding  domain of FimH and related proteins; Region: FimH_man-bind; cd10466
1006551015804	mannosyl binding site [chemical binding]; other site
1006551015805	Fimbrial protein; Region: Fimbrial; cl01416
1006551015806	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1006551015807	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
1006551015808	Glycoside Hydrolases Family 4; GlvA- and pagL-like glycosidases; Region: GH4_GlvA_pagL_like; cd05298
1006551015809	NAD binding site [chemical binding]; other site
1006551015810	sugar binding site [chemical binding]; other site
1006551015811	divalent metal binding site [ion binding]; other site
1006551015812	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
1006551015813	dimer interface [polypeptide binding]; other site
1006551015814	PTS system, alpha-glucoside-specific IIBC component; Region: PTS-IIBC-alpha; TIGR02005
1006551015815	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1006551015816	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1006551015817	active site turn [active]
1006551015818	phosphorylation site [posttranslational modification]
1006551015819	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1006551015820	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551015821	DNA-binding site [nucleotide binding]; DNA binding site
1006551015822	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
1006551015823	Domain of unknown function (DUF1869); Region: DUF1869; pfam08956
1006551015824	Domain of unknown function (DUF1971); Region: DUF1971; cl17717
1006551015825	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1006551015826	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1006551015827	metal binding site [ion binding]; metal-binding site
1006551015828	active site
1006551015829	I-site; other site
1006551015830	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1006551015831	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1006551015832	shikimate transporter; Provisional; Region: PRK09952
1006551015833	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551015834	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551015835	putative substrate translocation pore; other site
1006551015836	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
1006551015837	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551015838	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551015839	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1006551015840	putative effector binding pocket; other site
1006551015841	dimerization interface [polypeptide binding]; other site
1006551015842	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235
1006551015843	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1006551015844	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1006551015845	DNA binding site [nucleotide binding]
1006551015846	domain linker motif; other site
1006551015847	Ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_LacI_like_2; cd06278
1006551015848	putative dimerization interface [polypeptide binding]; other site
1006551015849	putative ligand binding site [chemical binding]; other site
1006551015850	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1006551015851	AP endonuclease family 2 C terminus; Region: AP_endonuc_2_N; pfam07582
1006551015852	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1006551015853	active site
1006551015854	phosphorylation site [posttranslational modification]
1006551015855	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1006551015856	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1006551015857	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1006551015858	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
1006551015859	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551015860	putative substrate translocation pore; other site
1006551015861	HPP family; Region: HPP; pfam04982
1006551015862	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
1006551015863	NAD binding site [chemical binding]; other site
1006551015864	cobalamin synthase; Reviewed; Region: cobS; PRK00235
1006551015865	Cobinamide kinase / cobinamide phosphate guanyltransferase; Region: CobU; cl17363
1006551015866	hypothetical protein; Provisional; Region: PRK05423
1006551015867	Predicted membrane protein [Function unknown]; Region: COG1289
1006551015868	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1006551015869	DNA gyrase inhibitor; Provisional; Region: PRK10016
1006551015870	Capsule assembly protein Wzi; Region: Caps_assemb_Wzi; pfam14052
1006551015871	D-alanyl-D-alanine carboxypeptidase; Provisional; Region: dacD; PRK11397
1006551015872	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1006551015873	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
1006551015874	exonuclease I; Provisional; Region: sbcB; PRK11779
1006551015875	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
1006551015876	active site
1006551015877	catalytic site [active]
1006551015878	substrate binding site [chemical binding]; other site
1006551015879	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
1006551015880	elongation factor G; Reviewed; Region: PRK00007
1006551015881	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1006551015882	G1 box; other site
1006551015883	putative GEF interaction site [polypeptide binding]; other site
1006551015884	GTP/Mg2+ binding site [chemical binding]; other site
1006551015885	Switch I region; other site
1006551015886	G2 box; other site
1006551015887	G3 box; other site
1006551015888	Switch II region; other site
1006551015889	G4 box; other site
1006551015890	G5 box; other site
1006551015891	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1006551015892	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1006551015893	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1006551015894	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1006551015895	dimerization interface [polypeptide binding]; other site
1006551015896	putative DNA binding site [nucleotide binding]; other site
1006551015897	putative Zn2+ binding site [ion binding]; other site
1006551015898	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
1006551015899	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
1006551015900	dimer interface [polypeptide binding]; other site
1006551015901	PYR/PP interface [polypeptide binding]; other site
1006551015902	TPP binding site [chemical binding]; other site
1006551015903	substrate binding site [chemical binding]; other site
1006551015904	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
1006551015905	Domain of unknown function; Region: EKR; pfam10371
1006551015906	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1006551015907	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
1006551015908	TPP-binding site [chemical binding]; other site
1006551015909	dimer interface [polypeptide binding]; other site
1006551015910	NifH gene encodes component II (iron protein) of nitrogenase. Nitrogenase is responsible for the biological nitrogen fixation, i.e. reduction of molecular nitrogen to ammonia. NifH consists of two oxygen-sensitive metallosulfur proteins: the...; Region: NifH; cd02040
1006551015911	nitrogenase iron protein; Region: nifH; TIGR01287
1006551015912	Nucleotide-binding sites [chemical binding]; other site
1006551015913	Walker A motif; other site
1006551015914	Switch I region of nucleotide binding site; other site
1006551015915	Fe4S4 binding sites [ion binding]; other site
1006551015916	Switch II region of nucleotide binding site; other site
1006551015917	nitrogenase molybdenum-iron cofactor biosynthesis protein NifE; Region: nifE; TIGR01283
1006551015918	Nitrogenase_MoFe_alpha_II: Nitrogenase MoFe protein, beta subunit. A group of proteins similar to the alpha subunit of the MoFe protein of the molybdenum (Mo-) nitrogenase. The nitrogenase enzyme catalyzes the ATP-dependent reduction of dinitrogen to...; Region: Nitrogenase_MoFe_alpha; cd01976
1006551015919	MoFe protein alpha/beta subunit interactions; other site
1006551015920	Alpha subunit P cluster binding residues; other site
1006551015921	FeMoco binding residues [chemical binding]; other site
1006551015922	MoFe protein alpha subunit/Fe protein contacts; other site
1006551015923	MoFe protein dimer/ dimer interactions; other site
1006551015924	nitrogenase molybdenum-iron protein beta chain; Region: nifK; TIGR01286
1006551015925	Domain of unknown function (DUF3364); Region: DUF3364; pfam11844
1006551015926	Nitrogenase_MoFe_beta: Nitrogenase MoFe protein, beta subunit. The nitrogenase enzyme catalyzes the ATP-dependent reduction of dinitrogen to ammonia. The Molybdenum (Mo-) nitrogenase is the most widespread and best characterized of these systems; Region: Nitrogenase_MoFe_beta; cd01974
1006551015927	MoFe protein beta/alpha subunit interactions; other site
1006551015928	Beta subunit P cluster binding residues; other site
1006551015929	MoFe protein beta subunit/Fe protein contacts; other site
1006551015930	MoFe protein dimer/ dimer interactions; other site
1006551015931	NifT/FixU protein; Region: NifT; pfam06988
1006551015932	NifX belongs to a family of iron-molybdenum cluster-binding proteins that includes NifB,  and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of the dinitrogenase enzyme.  The protein...; Region: NifX; cd00853
1006551015933	nitrogenase molybdenum-iron cofactor biosynthesis protein NifE; Region: nifE; TIGR01283
1006551015934	The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia.  This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cl02775
1006551015935	Nitrogenase_nifN1: A subgroup of the NifN subunit of the NifEN complex: NifN forms an alpha2beta2 tetramer with NifE.  NifN and nifE are structurally homologous to nitrogenase MoFe protein beta and alpha subunits respectively.  NifEN participates in the...; Region: Nitrogenase_NifN_1; cd01966
1006551015936	Nitrogenase component 1 type Oxidoreductase; Region: Oxidored_nitro; pfam00148
1006551015937	NifX belongs to a family of iron-molybdenum cluster-binding proteins that includes NifB,  and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of the dinitrogenase enzyme.  The protein...; Region: NifX; cd00853
1006551015938	Fe-S cluster assembly protein NifU; Region: NifU_proper; TIGR02000
1006551015939	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
1006551015940	trimerization site [polypeptide binding]; other site
1006551015941	active site
1006551015942	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1006551015943	NifU-like domain; Region: NifU; pfam01106
1006551015944	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
1006551015945	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1006551015946	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1006551015947	catalytic residue [active]
1006551015948	homocitrate synthase NifV; Region: nifV_homocitr; TIGR02660
1006551015949	Streptomyces rubellomurinus FrbC and related proteins, catalytic TIM barrel domain; Region: DRE_TIM_NifV; cd07939
1006551015950	active site
1006551015951	catalytic residues [active]
1006551015952	metal binding site [ion binding]; metal-binding site
1006551015953	Nitrogen fixation protein NifW; Region: NifW; cl03935
1006551015954	NifZ domain; Region: NifZ; pfam04319
1006551015955	nitrogen fixation protein NifM; Region: nifM_nitrog; TIGR02933
1006551015956	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1006551015957	flavodoxin FldA; Validated; Region: PRK09267
1006551015958	nitrogen fixation negative regulator NifL; Region: nifL_nitrog; TIGR02938
1006551015959	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1006551015960	putative active site [active]
1006551015961	heme pocket [chemical binding]; other site
1006551015962	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551015963	ATP binding site [chemical binding]; other site
1006551015964	G-X-G motif; other site
1006551015965	Nif-specific regulatory protein; Region: nifA; TIGR01817
1006551015966	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1006551015967	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1006551015968	Walker A motif; other site
1006551015969	ATP binding site [chemical binding]; other site
1006551015970	Walker B motif; other site
1006551015971	arginine finger; other site
1006551015972	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1006551015973	nitrogenase cofactor biosynthesis protein NifB; Region: nifB; TIGR01290
1006551015974	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1006551015975	FeS/SAM binding site; other site
1006551015976	NifB belongs to a family of iron-molybdenum cluster-binding proteins that includes NifX, and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of the dinitrogenase enzyme as part of...; Region: NifB; cd00852
1006551015977	NifQ; Region: NifQ; pfam04891
1006551015978	amino acid transporter; Region: 2A0306; TIGR00909
1006551015979	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551015980	transcriptional regulator, ArgP family; Region: argP; TIGR03298
1006551015981	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1006551015982	dimerization interface [polypeptide binding]; other site
1006551015983	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1006551015984	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
1006551015985	putative NAD(P) binding site [chemical binding]; other site
1006551015986	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
1006551015987	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
1006551015988	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
1006551015989	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
1006551015990	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
1006551015991	NAD binding site [chemical binding]; other site
1006551015992	dimerization interface [polypeptide binding]; other site
1006551015993	product binding site; other site
1006551015994	substrate binding site [chemical binding]; other site
1006551015995	zinc binding site [ion binding]; other site
1006551015996	catalytic residues [active]
1006551015997	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
1006551015998	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1006551015999	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551016000	homodimer interface [polypeptide binding]; other site
1006551016001	catalytic residue [active]
1006551016002	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
1006551016003	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1006551016004	active site
1006551016005	motif I; other site
1006551016006	motif II; other site
1006551016007	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
1006551016008	putative active site pocket [active]
1006551016009	4-fold oligomerization interface [polypeptide binding]; other site
1006551016010	metal binding residues [ion binding]; metal-binding site
1006551016011	3-fold/trimer interface [polypeptide binding]; other site
1006551016012	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
1006551016013	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
1006551016014	putative active site [active]
1006551016015	oxyanion strand; other site
1006551016016	catalytic triad [active]
1006551016017	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
1006551016018	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
1006551016019	catalytic residues [active]
1006551016020	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
1006551016021	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
1006551016022	substrate binding site [chemical binding]; other site
1006551016023	glutamase interaction surface [polypeptide binding]; other site
1006551016024	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
1006551016025	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
1006551016026	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
1006551016027	metal binding site [ion binding]; metal-binding site
1006551016028	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1006551016029	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1006551016030	active site
1006551016031	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
1006551016032	This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808
1006551016033	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1006551016034	putative ADP-binding pocket [chemical binding]; other site
1006551016035	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
1006551016036	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1006551016037	active site
1006551016038	UDP-galactopyranose mutase [Cell envelope biogenesis, outer membrane]; Region: Glf; COG0562
1006551016039	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1006551016040	UDP-galactopyranose mutase; Region: GLF; pfam03275
1006551016041	Domain of unknown function (DUF4422); Region: DUF4422; pfam14393
1006551016042	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
1006551016043	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
1006551016044	Ligand binding site; other site
1006551016045	metal-binding site
1006551016046	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
1006551016047	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
1006551016048	Walker A/P-loop; other site
1006551016049	ATP binding site [chemical binding]; other site
1006551016050	Q-loop/lid; other site
1006551016051	ABC transporter signature motif; other site
1006551016052	Walker B; other site
1006551016053	D-loop; other site
1006551016054	H-loop/switch region; other site
1006551016055	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
1006551016056	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1006551016057	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1006551016058	UDP glucuronic acid epimerase, extended (e) SDRs; Region: UDP_GE_SDE_e; cd05253
1006551016059	putative NAD(P) binding site [chemical binding]; other site
1006551016060	active site
1006551016061	putative substrate binding site [chemical binding]; other site
1006551016062	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
1006551016063	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1006551016064	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1006551016065	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1006551016066	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
1006551016067	dTDP-4-dehydrorhamnose reductase; Provisional; Region: PRK09987
1006551016068	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
1006551016069	NADP binding site [chemical binding]; other site
1006551016070	active site
1006551016071	putative substrate binding site [chemical binding]; other site
1006551016072	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
1006551016073	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
1006551016074	substrate binding site; other site
1006551016075	tetramer interface; other site
1006551016076	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
1006551016077	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
1006551016078	NAD binding site [chemical binding]; other site
1006551016079	substrate binding site [chemical binding]; other site
1006551016080	homodimer interface [polypeptide binding]; other site
1006551016081	active site
1006551016082	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1006551016083	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
1006551016084	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
1006551016085	potential frameshift: common BLAST hit: gi|322834279|ref|YP_004214306.1| polysaccharide biosynthesis protein
1006551016086	This family is most closely related to the GT1 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be...; Region: GT1_amsD_like; cd03820
1006551016087	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1006551016088	putative ADP-binding pocket [chemical binding]; other site
1006551016089	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1006551016090	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1006551016091	active site
1006551016092	Core-2/I-Branching enzyme; Region: Branch; pfam02485
1006551016093	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1006551016094	undecaprenyl-phosphate galactose phosphotransferase; Provisional; Region: PRK15204
1006551016095	Bacterial sugar transferase; Region: Bac_transf; pfam02397
1006551016096	tyrosine kinase; Provisional; Region: PRK11519
1006551016097	Chain length determinant protein; Region: Wzz; pfam02706
1006551016098	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1006551016099	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
1006551016100	Nucleotide binding site [chemical binding]; other site
1006551016101	DTAP/Switch II; other site
1006551016102	Switch I; other site
1006551016103	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1006551016104	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
1006551016105	active site
1006551016106	polysaccharide export protein Wza; Provisional; Region: PRK15078
1006551016107	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1006551016108	SLBB domain; Region: SLBB; pfam10531
1006551016109	Capsule assembly protein Wzi; Region: Caps_assemb_Wzi; pfam14052
1006551016110	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
1006551016111	active site
1006551016112	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1006551016113	active site
1006551016114	tetramer interface; other site
1006551016115	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1006551016116	Putative Mg2+ and Co2+ transporter CorC [Inorganic ion transport and metabolism]; Region: CorC; COG4535
1006551016117	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1006551016118	Transporter associated domain; Region: CorC_HlyC; smart01091
1006551016119	putative assembly protein; Provisional; Region: PRK10833
1006551016120	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1006551016121	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1006551016122	trimer interface [polypeptide binding]; other site
1006551016123	active site
1006551016124	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
1006551016125	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
1006551016126	ATP-binding site [chemical binding]; other site
1006551016127	Sugar specificity; other site
1006551016128	Pyrimidine base specificity; other site
1006551016129	3-methyl-adenine DNA glycosylase II; Provisional; Region: PRK10308
1006551016130	AlkA N-terminal domain; Region: AlkA_N; pfam06029
1006551016131	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1006551016132	minor groove reading motif; other site
1006551016133	helix-hairpin-helix signature motif; other site
1006551016134	substrate binding pocket [chemical binding]; other site
1006551016135	active site
1006551016136	putative chaperone; Provisional; Region: PRK11678
1006551016137	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
1006551016138	nucleotide binding site [chemical binding]; other site
1006551016139	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1006551016140	SBD interface [polypeptide binding]; other site
1006551016141	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
1006551016142	dimer interface [polypeptide binding]; other site
1006551016143	Citrate synthase; Region: Citrate_synt; pfam00285
1006551016144	active site
1006551016145	citrylCoA binding site [chemical binding]; other site
1006551016146	NADH binding [chemical binding]; other site
1006551016147	cationic pore residues; other site
1006551016148	oxalacetate/citrate binding site [chemical binding]; other site
1006551016149	coenzyme A binding site [chemical binding]; other site
1006551016150	catalytic triad [active]
1006551016151	7TMR-DISM extracellular 2; Region: 7TMR-DISMED2; pfam07696
1006551016152	7TM diverse intracellular signalling; Region: 7TMR-DISM_7TM; pfam07695
1006551016153	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1006551016154	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1006551016155	dimer interface [polypeptide binding]; other site
1006551016156	phosphorylation site [posttranslational modification]
1006551016157	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551016158	ATP binding site [chemical binding]; other site
1006551016159	Mg2+ binding site [ion binding]; other site
1006551016160	G-X-G motif; other site
1006551016161	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1006551016162	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551016163	active site
1006551016164	phosphorylation site [posttranslational modification]
1006551016165	intermolecular recognition site; other site
1006551016166	dimerization interface [polypeptide binding]; other site
1006551016167	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1006551016168	DNA binding site [nucleotide binding]
1006551016169	potential frameshift: common BLAST hit: gi|288934417|ref|YP_003438476.1| LuxR family transcriptional regulator
1006551016170	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1006551016171	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
1006551016172	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1006551016173	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cd00995
1006551016174	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1006551016175	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1006551016176	Walker A/P-loop; other site
1006551016177	ATP binding site [chemical binding]; other site
1006551016178	Q-loop/lid; other site
1006551016179	ABC transporter signature motif; other site
1006551016180	Walker B; other site
1006551016181	D-loop; other site
1006551016182	H-loop/switch region; other site
1006551016183	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1006551016184	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1006551016185	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1006551016186	Walker A/P-loop; other site
1006551016187	ATP binding site [chemical binding]; other site
1006551016188	Q-loop/lid; other site
1006551016189	ABC transporter signature motif; other site
1006551016190	Walker B; other site
1006551016191	D-loop; other site
1006551016192	H-loop/switch region; other site
1006551016193	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1006551016194	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1006551016195	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1006551016196	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551016197	dimer interface [polypeptide binding]; other site
1006551016198	conserved gate region; other site
1006551016199	putative PBP binding loops; other site
1006551016200	ABC-ATPase subunit interface; other site
1006551016201	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1006551016202	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551016203	dimer interface [polypeptide binding]; other site
1006551016204	conserved gate region; other site
1006551016205	putative PBP binding loops; other site
1006551016206	ABC-ATPase subunit interface; other site
1006551016207	proline-specific peptidase, Bacillus coagulans-type subfamily; Region: pro_imino_pep_2; TIGR01250
1006551016208	Novel bacterial esterase that cleaves esters on halogenated cyclic compounds; Region: Esterase_713_like; cl17303
1006551016209	catalytic site [active]
1006551016210	LuxR family transcriptional regulatory, chaperone HchA-associated; Region: reg_near_HchA; TIGR03541
1006551016211	Autoinducer binding domain; Region: Autoind_bind; pfam03472
1006551016212	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1006551016213	DNA binding residues [nucleotide binding]
1006551016214	dimerization interface [polypeptide binding]; other site
1006551016215	proline-specific peptidase, Bacillus coagulans-type subfamily; Region: pro_imino_pep_2; TIGR01250
1006551016216	Peptidase M14 Succinylglutamate desuccinylase (ASTE)/aspartoacylase (ASPA)-like subfamily; subgroup includes Pseudomonas aeruginosa AotO; Region: M14_PaAOTO_like; cd06250
1006551016217	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
1006551016218	active site
1006551016219	Zn binding site [ion binding]; other site
1006551016220	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1006551016221	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
1006551016222	AsnC family; Region: AsnC_trans_reg; pfam01037
1006551016223	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1006551016224	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551016225	dimer interface [polypeptide binding]; other site
1006551016226	conserved gate region; other site
1006551016227	putative PBP binding loops; other site
1006551016228	ABC-ATPase subunit interface; other site
1006551016229	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1006551016230	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551016231	dimer interface [polypeptide binding]; other site
1006551016232	conserved gate region; other site
1006551016233	putative PBP binding loops; other site
1006551016234	ABC-ATPase subunit interface; other site
1006551016235	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551016236	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1006551016237	substrate binding pocket [chemical binding]; other site
1006551016238	membrane-bound complex binding site; other site
1006551016239	hinge residues; other site
1006551016240	Amidinotransferase; Region: Amidinotransf; cl12043
1006551016241	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
1006551016242	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1006551016243	HlyD family secretion protein; Region: HlyD_3; pfam13437
1006551016244	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
1006551016245	Protein export membrane protein; Region: SecD_SecF; cl14618
1006551016246	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
1006551016247	putative transporter; Provisional; Region: PRK10504
1006551016248	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551016249	putative substrate translocation pore; other site
1006551016250	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551016251	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
1006551016252	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1006551016253	dimerization interface [polypeptide binding]; other site
1006551016254	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1006551016255	dimer interface [polypeptide binding]; other site
1006551016256	phosphorylation site [posttranslational modification]
1006551016257	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551016258	ATP binding site [chemical binding]; other site
1006551016259	Mg2+ binding site [ion binding]; other site
1006551016260	G-X-G motif; other site
1006551016261	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
1006551016262	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551016263	active site
1006551016264	phosphorylation site [posttranslational modification]
1006551016265	intermolecular recognition site; other site
1006551016266	dimerization interface [polypeptide binding]; other site
1006551016267	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1006551016268	DNA binding site [nucleotide binding]
1006551016269	putative protease; Provisional; Region: PRK15452
1006551016270	Peptidase family U32; Region: Peptidase_U32; pfam01136
1006551016271	lipid kinase; Reviewed; Region: PRK13054
1006551016272	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
1006551016273	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
1006551016274	DNA binding site [nucleotide binding]
1006551016275	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1006551016276	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1006551016277	Walker A/P-loop; other site
1006551016278	ATP binding site [chemical binding]; other site
1006551016279	Q-loop/lid; other site
1006551016280	ABC transporter signature motif; other site
1006551016281	Walker B; other site
1006551016282	D-loop; other site
1006551016283	H-loop/switch region; other site
1006551016284	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1006551016285	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1006551016286	Walker A/P-loop; other site
1006551016287	ATP binding site [chemical binding]; other site
1006551016288	Q-loop/lid; other site
1006551016289	ABC transporter signature motif; other site
1006551016290	Walker B; other site
1006551016291	D-loop; other site
1006551016292	H-loop/switch region; other site
1006551016293	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1006551016294	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1006551016295	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1006551016296	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551016297	dimer interface [polypeptide binding]; other site
1006551016298	conserved gate region; other site
1006551016299	ABC-ATPase subunit interface; other site
1006551016300	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1006551016301	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551016302	dimer interface [polypeptide binding]; other site
1006551016303	conserved gate region; other site
1006551016304	putative PBP binding loops; other site
1006551016305	ABC-ATPase subunit interface; other site
1006551016306	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1006551016307	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_7; cd08512
1006551016308	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
1006551016309	Mandelate racemase (MR)-like subfamily of the enolase superfamily, subgroup 4. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic...; Region: MR_like_4; cd03329
1006551016310	putative active site pocket [active]
1006551016311	metal binding site [ion binding]; metal-binding site
1006551016312	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
1006551016313	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1006551016314	motif II; other site
1006551016315	polyol permease family; Region: 2A0118; TIGR00897
1006551016316	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551016317	putative substrate translocation pore; other site
1006551016318	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
1006551016319	N- and C-terminal domain interface [polypeptide binding]; other site
1006551016320	D-xylulose kinase; Region: XylB; TIGR01312
1006551016321	active site
1006551016322	MgATP binding site [chemical binding]; other site
1006551016323	catalytic site [active]
1006551016324	metal binding site [ion binding]; metal-binding site
1006551016325	xylulose binding site [chemical binding]; other site
1006551016326	homodimer interface [polypeptide binding]; other site
1006551016327	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1006551016328	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
1006551016329	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1006551016330	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
1006551016331	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
1006551016332	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
1006551016333	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1006551016334	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1006551016335	DNA binding site [nucleotide binding]
1006551016336	domain linker motif; other site
1006551016337	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
1006551016338	dimerization interface [polypeptide binding]; other site
1006551016339	ligand binding site [chemical binding]; other site
1006551016340	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
1006551016341	classical (c) SDRs; Region: SDR_c; cd05233
1006551016342	NAD(P) binding site [chemical binding]; other site
1006551016343	active site
1006551016344	Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_YpCarbK_like; cd07782
1006551016345	FGGY-family pentulose kinase; Region: 5C_CHO_kinase; TIGR01315
1006551016346	N- and C-terminal domain interface [polypeptide binding]; other site
1006551016347	active site
1006551016348	MgATP binding site [chemical binding]; other site
1006551016349	catalytic site [active]
1006551016350	metal binding site [ion binding]; metal-binding site
1006551016351	carbohydrate binding site [chemical binding]; other site
1006551016352	putative homodimer interface [polypeptide binding]; other site
1006551016353	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
1006551016354	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
1006551016355	putative active site; other site
1006551016356	catalytic residue [active]
1006551016357	nucleoside transporter; Region: 2A0110; TIGR00889
1006551016358	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551016359	putative substrate translocation pore; other site
1006551016360	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
1006551016361	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1006551016362	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
1006551016363	substrate binding site [chemical binding]; other site
1006551016364	ATP binding site [chemical binding]; other site
1006551016365	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1006551016366	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551016367	DNA-binding site [nucleotide binding]; DNA binding site
1006551016368	UTRA domain; Region: UTRA; pfam07702
1006551016369	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
1006551016370	dimer interface [polypeptide binding]; other site
1006551016371	substrate binding site [chemical binding]; other site
1006551016372	ATP binding site [chemical binding]; other site
1006551016373	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
1006551016374	substrate binding site [chemical binding]; other site
1006551016375	multimerization interface [polypeptide binding]; other site
1006551016376	ATP binding site [chemical binding]; other site
1006551016377	Alkyl sulfatase and related hydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2015
1006551016378	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1006551016379	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
1006551016380	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551016381	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551016382	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1006551016383	dimerization interface [polypeptide binding]; other site
1006551016384	Adenine deaminase [Nucleotide transport and metabolism]; Region: AdeC; COG1001
1006551016385	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1006551016386	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1006551016387	active site
1006551016388	Adenine deaminase C-terminal domain; Region: Adenine_deam_C; pfam13382
1006551016389	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1006551016390	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551016391	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551016392	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1006551016393	putative effector binding pocket; other site
1006551016394	dimerization interface [polypeptide binding]; other site
1006551016395	Domain of unknown function (DUF3315); Region: DUF3315; cl02275
1006551016396	antiporter inner membrane protein; Provisional; Region: PRK11670
1006551016397	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
1006551016398	Walker A motif; other site
1006551016399	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
1006551016400	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
1006551016401	active site
1006551016402	HIGH motif; other site
1006551016403	KMSKS motif; other site
1006551016404	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1006551016405	tRNA binding surface [nucleotide binding]; other site
1006551016406	anticodon binding site; other site
1006551016407	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
1006551016408	dimer interface [polypeptide binding]; other site
1006551016409	putative tRNA-binding site [nucleotide binding]; other site
1006551016410	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
1006551016411	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
1006551016412	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
1006551016413	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
1006551016414	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
1006551016415	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551016416	active site
1006551016417	phosphorylation site [posttranslational modification]
1006551016418	intermolecular recognition site; other site
1006551016419	dimerization interface [polypeptide binding]; other site
1006551016420	LytTr DNA-binding domain; Region: LytTR; pfam04397
1006551016421	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
1006551016422	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
1006551016423	GAF domain; Region: GAF; pfam01590
1006551016424	Histidine kinase; Region: His_kinase; pfam06580
1006551016425	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551016426	ATP binding site [chemical binding]; other site
1006551016427	Mg2+ binding site [ion binding]; other site
1006551016428	G-X-G motif; other site
1006551016429	transcriptional regulator MirA; Provisional; Region: PRK15043
1006551016430	Helix-Turn-Helix DNA binding domain of MlrA-like transcription regulators; Region: HTH_MlrA-like; cd04763
1006551016431	DNA binding residues [nucleotide binding]
1006551016432	hypothetical protein; Provisional; Region: PRK13681
1006551016433	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551016434	putative PBP binding loops; other site
1006551016435	ABC-ATPase subunit interface; other site
1006551016436	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
1006551016437	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
1006551016438	Walker A/P-loop; other site
1006551016439	ATP binding site [chemical binding]; other site
1006551016440	Q-loop/lid; other site
1006551016441	ABC transporter signature motif; other site
1006551016442	Walker B; other site
1006551016443	D-loop; other site
1006551016444	H-loop/switch region; other site
1006551016445	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
1006551016446	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
1006551016447	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
1006551016448	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
1006551016449	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1006551016450	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1006551016451	D-lactate dehydrogenase; Provisional; Region: PRK11183
1006551016452	FAD binding domain; Region: FAD_binding_4; pfam01565
1006551016453	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
1006551016454	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
1006551016455	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1006551016456	Coenzyme A binding pocket [chemical binding]; other site
1006551016457	D-alanyl-D-alanine endopeptidase; Provisional; Region: pbpG; PRK11669
1006551016458	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
1006551016459	Protein of unknown function (DUF1282); Region: DUF1282; pfam06930
1006551016460	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1006551016461	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1006551016462	Outer membrane efflux protein; Region: OEP; pfam02321
1006551016463	Outer membrane efflux protein; Region: OEP; pfam02321
1006551016464	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551016465	S-adenosylmethionine binding site [chemical binding]; other site
1006551016466	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
1006551016467	beta-galactosidase; Region: BGL; TIGR03356
1006551016468	PTS system beta-glucoside-specific transporter subunits IIABC; Provisional; Region: PRK09824
1006551016469	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1006551016470	active site turn [active]
1006551016471	phosphorylation site [posttranslational modification]
1006551016472	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1006551016473	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1006551016474	HPr interaction site; other site
1006551016475	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1006551016476	active site
1006551016477	phosphorylation site [posttranslational modification]
1006551016478	transcriptional antiterminator BglG; Provisional; Region: PRK09772
1006551016479	CAT RNA binding domain; Region: CAT_RBD; smart01061
1006551016480	PRD domain; Region: PRD; pfam00874
1006551016481	PRD domain; Region: PRD; pfam00874
1006551016482	tRNA-dihydrouridine synthase C; Provisional; Region: PRK10550
1006551016483	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1006551016484	FMN binding site [chemical binding]; other site
1006551016485	active site
1006551016486	catalytic residues [active]
1006551016487	substrate binding site [chemical binding]; other site
1006551016488	salicylate hydroxylase; Provisional; Region: PRK08163
1006551016489	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1006551016490	GST_N family, Class Zeta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Zeta; cd03042
1006551016491	maleylacetoacetate isomerase; Region: maiA; TIGR01262
1006551016492	C-terminal domain interface [polypeptide binding]; other site
1006551016493	GSH binding site (G-site) [chemical binding]; other site
1006551016494	putative dimer interface [polypeptide binding]; other site
1006551016495	C-terminal, alpha helical domain of Class Zeta Glutathione S-transferases; Region: GST_C_Zeta; cd03191
1006551016496	dimer interface [polypeptide binding]; other site
1006551016497	N-terminal domain interface [polypeptide binding]; other site
1006551016498	maleylacetoacetate (MAA) substrate binding site (H site) [chemical binding]; other site
1006551016499	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1006551016500	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1006551016501	gentisate 1,2-dioxygenase; Region: gentisate_1_2; TIGR02272
1006551016502	Cupin domain; Region: Cupin_2; pfam07883
1006551016503	Cupin domain; Region: Cupin_2; pfam07883
1006551016504	benzoate transport; Region: 2A0115; TIGR00895
1006551016505	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551016506	putative substrate translocation pore; other site
1006551016507	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551016508	putative substrate translocation pore; other site
1006551016509	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551016510	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551016511	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1006551016512	dimerization interface [polypeptide binding]; other site
1006551016513	hypothetical protein; Provisional; Region: PRK01821
1006551016514	hypothetical protein; Provisional; Region: PRK10711
1006551016515	cytidine deaminase; Provisional; Region: PRK09027
1006551016516	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1006551016517	active site
1006551016518	catalytic motif [active]
1006551016519	Zn binding site [ion binding]; other site
1006551016520	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1006551016521	active site
1006551016522	catalytic motif [active]
1006551016523	Zn binding site [ion binding]; other site
1006551016524	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1006551016525	putative active site [active]
1006551016526	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1006551016527	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1006551016528	TM-ABC transporter signature motif; other site
1006551016529	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1006551016530	galactose/methyl galaxtoside transporter ATP-binding protein; Provisional; Region: PRK10982
1006551016531	Walker A/P-loop; other site
1006551016532	ATP binding site [chemical binding]; other site
1006551016533	Q-loop/lid; other site
1006551016534	ABC transporter signature motif; other site
1006551016535	Walker B; other site
1006551016536	D-loop; other site
1006551016537	H-loop/switch region; other site
1006551016538	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1006551016539	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
1006551016540	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
1006551016541	ligand binding site [chemical binding]; other site
1006551016542	calcium binding site [ion binding]; other site
1006551016543	DNA-binding transcriptional regulator GalS; Provisional; Region: PRK10401
1006551016544	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1006551016545	DNA binding site [nucleotide binding]
1006551016546	domain linker motif; other site
1006551016547	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1006551016548	dimerization interface (closed form) [polypeptide binding]; other site
1006551016549	ligand binding site [chemical binding]; other site
1006551016550	Predicted membrane protein [Function unknown]; Region: COG2311
1006551016551	hypothetical protein; Provisional; Region: PRK10835
1006551016552	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
1006551016553	GTP cyclohydrolase I; Provisional; Region: PLN03044
1006551016554	active site
1006551016555	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
1006551016556	S-formylglutathione hydrolase; Region: PLN02442
1006551016557	catecholate siderophore receptor CirA; Provisional; Region: PRK10064
1006551016558	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1006551016559	N-terminal plug; other site
1006551016560	ligand-binding site [chemical binding]; other site
1006551016561	lysine transporter; Provisional; Region: PRK10836
1006551016562	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
1006551016563	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551016564	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
1006551016565	putative dimerization interface [polypeptide binding]; other site
1006551016566	Conserved hypothetical protein 698; Region: Cons_hypoth698; cl01075
1006551016567	endonuclease IV; Provisional; Region: PRK01060
1006551016568	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1006551016569	AP (apurinic/apyrimidinic) site pocket; other site
1006551016570	DNA interaction; other site
1006551016571	Metal-binding active site; metal-binding site
1006551016572	putative kinase; Provisional; Region: PRK09954
1006551016573	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
1006551016574	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
1006551016575	substrate binding site [chemical binding]; other site
1006551016576	ATP binding site [chemical binding]; other site
1006551016577	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1006551016578	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1006551016579	Nucleoside recognition; Region: Gate; pfam07670
1006551016580	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1006551016581	Indigoidine synthase A like protein; Region: Indigoidine_A; pfam04227
1006551016582	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
1006551016583	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1006551016584	substrate binding site [chemical binding]; other site
1006551016585	ATP binding site [chemical binding]; other site
1006551016586	PTS system fructose-specific transporter subunits IIBC; Provisional; Region: PRK10712
1006551016587	N-terminal domain of the phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]; Region: COG3925
1006551016588	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1006551016589	active site
1006551016590	P-loop; other site
1006551016591	phosphorylation site [posttranslational modification]
1006551016592	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
1006551016593	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
1006551016594	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1006551016595	putative substrate binding site [chemical binding]; other site
1006551016596	putative ATP binding site [chemical binding]; other site
1006551016597	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
1006551016598	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1006551016599	active site
1006551016600	phosphorylation site [posttranslational modification]
1006551016601	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1006551016602	dimerization domain swap beta strand [polypeptide binding]; other site
1006551016603	regulatory protein interface [polypeptide binding]; other site
1006551016604	active site
1006551016605	regulatory phosphorylation site [posttranslational modification]; other site
1006551016606	sugar efflux transporter B; Provisional; Region: PRK15011
1006551016607	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551016608	putative substrate translocation pore; other site
1006551016609	Flagellin N-methylase; Region: FliB; cl00497
1006551016610	elongation factor P; Provisional; Region: PRK04542
1006551016611	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1006551016612	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1006551016613	RNA binding site [nucleotide binding]; other site
1006551016614	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1006551016615	RNA binding site [nucleotide binding]; other site
1006551016616	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
1006551016617	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1006551016618	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1006551016619	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
1006551016620	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
1006551016621	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
1006551016622	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1006551016623	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
1006551016624	active site
1006551016625	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
1006551016626	NlpC/P60 family; Region: NLPC_P60; pfam00877
1006551016627	phage resistance protein; Provisional; Region: PRK10551
1006551016628	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1006551016629	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1006551016630	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1006551016631	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
1006551016632	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
1006551016633	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551016634	dimer interface [polypeptide binding]; other site
1006551016635	conserved gate region; other site
1006551016636	putative PBP binding loops; other site
1006551016637	ABC-ATPase subunit interface; other site
1006551016638	microcin C ABC transporter permease; Provisional; Region: PRK15021
1006551016639	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551016640	dimer interface [polypeptide binding]; other site
1006551016641	conserved gate region; other site
1006551016642	ABC-ATPase subunit interface; other site
1006551016643	microcin C ABC transporter ATP-binding protein YejF; Provisional; Region: PRK15134
1006551016644	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1006551016645	Walker A/P-loop; other site
1006551016646	ATP binding site [chemical binding]; other site
1006551016647	Q-loop/lid; other site
1006551016648	ABC transporter signature motif; other site
1006551016649	Walker B; other site
1006551016650	D-loop; other site
1006551016651	H-loop/switch region; other site
1006551016652	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1006551016653	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1006551016654	Walker A/P-loop; other site
1006551016655	ATP binding site [chemical binding]; other site
1006551016656	Q-loop/lid; other site
1006551016657	ABC transporter signature motif; other site
1006551016658	Walker B; other site
1006551016659	D-loop; other site
1006551016660	H-loop/switch region; other site
1006551016661	hypothetical protein; Provisional; Region: PRK11835
1006551016662	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551016663	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
1006551016664	putative substrate translocation pore; other site
1006551016665	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
1006551016666	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1006551016667	RNA binding surface [nucleotide binding]; other site
1006551016668	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
1006551016669	active site
1006551016670	uracil binding [chemical binding]; other site
1006551016671	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
1006551016672	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1006551016673	ATP binding site [chemical binding]; other site
1006551016674	putative Mg++ binding site [ion binding]; other site
1006551016675	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1006551016676	nucleotide binding region [chemical binding]; other site
1006551016677	ATP-binding site [chemical binding]; other site
1006551016678	Ribosomal L40e family; Region: Ribosomal_L40e; cl00671
1006551016679	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1006551016680	5S rRNA interface [nucleotide binding]; other site
1006551016681	CTC domain interface [polypeptide binding]; other site
1006551016682	L16 interface [polypeptide binding]; other site
1006551016683	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
1006551016684	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1006551016685	dimer interface [polypeptide binding]; other site
1006551016686	ADP-ribose binding site [chemical binding]; other site
1006551016687	active site
1006551016688	nudix motif; other site
1006551016689	metal binding site [ion binding]; metal-binding site
1006551016690	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1006551016691	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1006551016692	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1006551016693	Nucleoid-associated protein [General function prediction only]; Region: COG3081
1006551016694	nucleoid-associated protein NdpA; Validated; Region: PRK00378
1006551016695	hypothetical protein; Provisional; Region: PRK13689
1006551016696	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
1006551016697	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
1006551016698	Sulfatase; Region: Sulfatase; cl17466
1006551016699	type VI secretion system lysozyme-like protein; Region: VI_zyme; TIGR03357
1006551016700	Type VI secretion lipoprotein; Region: T6SS-SciN; pfam12790
1006551016701	Protein of unknown function (DUF1305); Region: DUF1305; pfam06996
1006551016702	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
1006551016703	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
1006551016704	hypothetical protein; Provisional; Region: PRK10215
1006551016705	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
1006551016706	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
1006551016707	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
1006551016708	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
1006551016709	PAAR motif; Region: PAAR_motif; pfam05488
1006551016710	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1006551016711	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
1006551016712	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1006551016713	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1006551016714	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
1006551016715	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4253
1006551016716	potential frameshift: common BLAST hit: gi|291619698|ref|YP_003522440.1| ClpV
1006551016717	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
1006551016718	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1006551016719	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1006551016720	ligand binding site [chemical binding]; other site
1006551016721	Uncharacterized protein conserved in bacteria (DUF2077); Region: DUF2077; pfam09850
1006551016722	type VI secretion protein, VC_A0114 family; Region: VI_chp_4; TIGR03353
1006551016723	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
1006551016724	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517; cl05484
1006551016725	Protein of unknown function (DUF877); Region: DUF877; pfam05943
1006551016726	Protein of unknown function (DUF770); Region: DUF770; pfam05591
1006551016727	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1006551016728	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1006551016729	Protease Inhibitor Ecotin; homodimeric protease inhibitor; Region: Ecotin; cd00242
1006551016730	secondary substrate binding site; other site
1006551016731	primary substrate binding site; other site
1006551016732	inhibition loop; other site
1006551016733	dimerization interface [polypeptide binding]; other site
1006551016734	malate:quinone oxidoreductase; Validated; Region: PRK05257
1006551016735	malate:quinone-oxidoreductase; Region: mal_quin_oxido; TIGR01320
1006551016736	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
1006551016737	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
1006551016738	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1006551016739	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
1006551016740	MgtE intracellular N domain; Region: MgtE_N; smart00924
1006551016741	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
1006551016742	Divalent cation transporter; Region: MgtE; cl00786
1006551016743	multidrug transporter membrane component/ATP-binding component; Provisional; Region: PRK10522
1006551016744	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1006551016745	Walker A/P-loop; other site
1006551016746	ATP binding site [chemical binding]; other site
1006551016747	Q-loop/lid; other site
1006551016748	ABC transporter signature motif; other site
1006551016749	Walker B; other site
1006551016750	D-loop; other site
1006551016751	H-loop/switch region; other site
1006551016752	alpha-ketoglutarate-dependent dioxygenase AlkB; Provisional; Region: PRK15401
1006551016753	bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435
1006551016754	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
1006551016755	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551016756	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
1006551016757	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1006551016758	DNA binding site [nucleotide binding]
1006551016759	active site
1006551016760	thiamine biosynthesis lipoprotein ApbE; Provisional; Region: PRK10461
1006551016761	ApbE family; Region: ApbE; pfam02424
1006551016762	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1006551016763	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1006551016764	phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional; Region: PRK10618
1006551016765	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551016766	ATP binding site [chemical binding]; other site
1006551016767	G-X-G motif; other site
1006551016768	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1006551016769	putative binding surface; other site
1006551016770	active site
1006551016771	transcriptional regulator RcsB; Provisional; Region: PRK10840
1006551016772	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551016773	active site
1006551016774	phosphorylation site [posttranslational modification]
1006551016775	intermolecular recognition site; other site
1006551016776	dimerization interface [polypeptide binding]; other site
1006551016777	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1006551016778	DNA binding residues [nucleotide binding]
1006551016779	dimerization interface [polypeptide binding]; other site
1006551016780	hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841
1006551016781	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1006551016782	dimer interface [polypeptide binding]; other site
1006551016783	phosphorylation site [posttranslational modification]
1006551016784	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551016785	ATP binding site [chemical binding]; other site
1006551016786	Mg2+ binding site [ion binding]; other site
1006551016787	G-X-G motif; other site
1006551016788	RcsC Alpha-Beta-Loop (ABL); Region: RcsC; pfam09456
1006551016789	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551016790	active site
1006551016791	phosphorylation site [posttranslational modification]
1006551016792	intermolecular recognition site; other site
1006551016793	dimerization interface [polypeptide binding]; other site
1006551016794	DNA gyrase subunit A; Validated; Region: PRK05560
1006551016795	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1006551016796	CAP-like domain; other site
1006551016797	active site
1006551016798	primary dimer interface [polypeptide binding]; other site
1006551016799	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1006551016800	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1006551016801	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1006551016802	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1006551016803	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1006551016804	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1006551016805	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
1006551016806	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551016807	S-adenosylmethionine binding site [chemical binding]; other site
1006551016808	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
1006551016809	ATP cone domain; Region: ATP-cone; pfam03477
1006551016810	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1006551016811	active site
1006551016812	dimer interface [polypeptide binding]; other site
1006551016813	catalytic residues [active]
1006551016814	effector binding site; other site
1006551016815	R2 peptide binding site; other site
1006551016816	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1006551016817	dimer interface [polypeptide binding]; other site
1006551016818	putative radical transfer pathway; other site
1006551016819	diiron center [ion binding]; other site
1006551016820	tyrosyl radical; other site
1006551016821	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1006551016822	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1006551016823	catalytic loop [active]
1006551016824	iron binding site [ion binding]; other site
1006551016825	choline dehydrogenase; Validated; Region: PRK02106
1006551016826	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1006551016827	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
1006551016828	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551016829	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551016830	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1006551016831	putative effector binding pocket; other site
1006551016832	dimerization interface [polypeptide binding]; other site
1006551016833	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
1006551016834	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
1006551016835	active site
1006551016836	catalytic site [active]
1006551016837	metal binding site [ion binding]; metal-binding site
1006551016838	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
1006551016839	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551016840	putative substrate translocation pore; other site
1006551016841	sn-glycerol-3-phosphate dehydrogenase subunit A; Provisional; Region: glpA; PRK11101
1006551016842	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1006551016843	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1006551016844	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; COG3075
1006551016845	anaerobic glycerol-3-phosphate dehydrogenase subunit B; Validated; Region: PRK05329
1006551016846	glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; Region: glycerol3P_GlpC; TIGR03379
1006551016847	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1006551016848	Cysteine-rich domain; Region: CCG; pfam02754
1006551016849	Cysteine-rich domain; Region: CCG; pfam02754
1006551016850	2-keto-3-deoxy-L-rhamnonate aldolase; Provisional; Region: PRK10128
1006551016851	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
1006551016852	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551016853	putative substrate translocation pore; other site
1006551016854	L-rhamnonate dehydratase; Provisional; Region: PRK15440
1006551016855	Mandelate racemase (MR)-like subfamily of the enolase superfamily, subgroup 2. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic...; Region: MR_like_2; cd03327
1006551016856	putative active site pocket [active]
1006551016857	putative metal binding site [ion binding]; other site
1006551016858	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1006551016859	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1006551016860	Bacterial transcriptional regulator; Region: IclR; pfam01614
1006551016861	hypothetical protein; Provisional; Region: PRK03673
1006551016862	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
1006551016863	putative MPT binding site; other site
1006551016864	Competence-damaged protein; Region: CinA; cl00666
1006551016865	YfaZ precursor; Region: YfaZ; pfam07437
1006551016866	outer membrane protein; Region: OMP_w_GlyGly; TIGR04219
1006551016867	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
1006551016868	Clade 3 of the heme-binding enzyme catalase; Region: catalase_clade_3; cd08156
1006551016869	tetramer interface [polypeptide binding]; other site
1006551016870	heme binding pocket [chemical binding]; other site
1006551016871	NADPH binding site [chemical binding]; other site
1006551016872	putative transposase; Provisional; Region: PRK09857
1006551016873	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1006551016874	nucleoside triphosphatase NudI; Provisional; Region: PRK15472
1006551016875	Two-component sensor kinase N-terminal; Region: 2CSK_N; pfam08521
1006551016876	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1006551016877	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1006551016878	dimer interface [polypeptide binding]; other site
1006551016879	phosphorylation site [posttranslational modification]
1006551016880	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551016881	ATP binding site [chemical binding]; other site
1006551016882	Mg2+ binding site [ion binding]; other site
1006551016883	G-X-G motif; other site
1006551016884	transcriptional regulatory protein TctD; Provisional; Region: PRK15479
1006551016885	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551016886	active site
1006551016887	phosphorylation site [posttranslational modification]
1006551016888	intermolecular recognition site; other site
1006551016889	dimerization interface [polypeptide binding]; other site
1006551016890	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1006551016891	DNA binding site [nucleotide binding]
1006551016892	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3181
1006551016893	Tripartite tricarboxylate transporter TctB family; Region: TctB; pfam07331
1006551016894	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3333
1006551016895	hypothetical protein; Provisional; Region: PRK09867
1006551016896	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
1006551016897	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
1006551016898	acyl-activating enzyme (AAE) consensus motif; other site
1006551016899	putative AMP binding site [chemical binding]; other site
1006551016900	putative active site [active]
1006551016901	putative CoA binding site [chemical binding]; other site
1006551016902	O-succinylbenzoate synthase; Provisional; Region: PRK05105
1006551016903	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
1006551016904	active site
1006551016905	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1006551016906	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
1006551016907	substrate binding site [chemical binding]; other site
1006551016908	oxyanion hole (OAH) forming residues; other site
1006551016909	trimer interface [polypeptide binding]; other site
1006551016910	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
1006551016911	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
1006551016912	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
1006551016913	dimer interface [polypeptide binding]; other site
1006551016914	tetramer interface [polypeptide binding]; other site
1006551016915	PYR/PP interface [polypeptide binding]; other site
1006551016916	TPP binding site [chemical binding]; other site
1006551016917	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
1006551016918	TPP-binding site; other site
1006551016919	menaquinone-specific isochorismate synthase; Provisional; Region: PRK15012
1006551016920	chorismate binding enzyme; Region: Chorismate_bind; cl10555
1006551016921	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1006551016922	Coenzyme A binding pocket [chemical binding]; other site
1006551016923	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
1006551016924	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1006551016925	active site
1006551016926	DNA binding site [nucleotide binding]
1006551016927	Int/Topo IB signature motif; other site
1006551016928	Fimbrial protein; Region: Fimbrial; cl01416
1006551016929	Fimbrial protein; Region: Fimbrial; cl01416
1006551016930	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1006551016931	PapC N-terminal domain; Region: PapC_N; pfam13954
1006551016932	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1006551016933	PapC C-terminal domain; Region: PapC_C; pfam13953
1006551016934	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1006551016935	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1006551016936	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1006551016937	Fimbrial protein; Region: Fimbrial; cl01416
1006551016938	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1006551016939	DNA binding site [nucleotide binding]
1006551016940	Int/Topo IB signature motif; other site
1006551016941	active site
1006551016942	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
1006551016943	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1006551016944	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
1006551016945	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1006551016946	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
1006551016947	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
1006551016948	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1006551016949	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
1006551016950	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
1006551016951	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
1006551016952	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
1006551016953	4Fe-4S binding domain; Region: Fer4; pfam00037
1006551016954	4Fe-4S binding domain; Region: Fer4; pfam00037
1006551016955	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
1006551016956	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
1006551016957	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1006551016958	catalytic loop [active]
1006551016959	iron binding site [ion binding]; other site
1006551016960	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
1006551016961	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
1006551016962	[4Fe-4S] binding site [ion binding]; other site
1006551016963	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
1006551016964	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
1006551016965	SLBB domain; Region: SLBB; pfam10531
1006551016966	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; smart00928
1006551016967	NADH dehydrogenase subunit E; Validated; Region: PRK07539
1006551016968	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
1006551016969	putative dimer interface [polypeptide binding]; other site
1006551016970	[2Fe-2S] cluster binding site [ion binding]; other site
1006551016971	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
1006551016972	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
1006551016973	NADH dehydrogenase subunit D; Validated; Region: PRK06075
1006551016974	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
1006551016975	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
1006551016976	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
1006551016977	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551016978	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
1006551016979	putative dimerization interface [polypeptide binding]; other site
1006551016980	aminotransferase AlaT; Validated; Region: PRK09265
1006551016981	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1006551016982	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551016983	homodimer interface [polypeptide binding]; other site
1006551016984	catalytic residue [active]
1006551016985	5'-nucleotidase; Provisional; Region: PRK03826
1006551016986	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1006551016987	transmembrane helices; other site
1006551016988	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1006551016989	TrkA-C domain; Region: TrkA_C; pfam02080
1006551016990	TrkA-C domain; Region: TrkA_C; pfam02080
1006551016991	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
1006551016992	putative phosphatase; Provisional; Region: PRK11587
1006551016993	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1006551016994	motif II; other site
1006551016995	hypothetical protein; Validated; Region: PRK05445
1006551016996	hypothetical protein; Provisional; Region: PRK01816
1006551016997	propionate/acetate kinase; Provisional; Region: PRK12379
1006551016998	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
1006551016999	phosphate acetyltransferase; Reviewed; Region: PRK05632
1006551017000	DRTGG domain; Region: DRTGG; pfam07085
1006551017001	phosphate acetyltransferase; Region: pta; TIGR00651
1006551017002	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
1006551017003	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1006551017004	PYR/PP interface [polypeptide binding]; other site
1006551017005	dimer interface [polypeptide binding]; other site
1006551017006	TPP binding site [chemical binding]; other site
1006551017007	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1006551017008	transketolase; Reviewed; Region: PRK05899
1006551017009	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1006551017010	TPP-binding site [chemical binding]; other site
1006551017011	dimer interface [polypeptide binding]; other site
1006551017012	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK12996
1006551017013	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1006551017014	active site
1006551017015	P-loop; other site
1006551017016	phosphorylation site [posttranslational modification]
1006551017017	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1006551017018	active site
1006551017019	phosphorylation site [posttranslational modification]
1006551017020	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1006551017021	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1006551017022	DNA binding site [nucleotide binding]
1006551017023	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1006551017024	putative dimerization interface [polypeptide binding]; other site
1006551017025	putative ligand binding site [chemical binding]; other site
1006551017026	NUDIX hydrolase YfcD; Provisional; Region: PRK15393
1006551017027	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_38; cd04697
1006551017028	nudix motif; other site
1006551017029	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
1006551017030	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1006551017031	active site
1006551017032	metal binding site [ion binding]; metal-binding site
1006551017033	homotetramer interface [polypeptide binding]; other site
1006551017034	glutathione S-transferase; Provisional; Region: PRK15113
1006551017035	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
1006551017036	C-terminal domain interface [polypeptide binding]; other site
1006551017037	GSH binding site (G-site) [chemical binding]; other site
1006551017038	dimer interface [polypeptide binding]; other site
1006551017039	C-terminal, alpha helical domain of an unknown subfamily 4 of Glutathione S-transferases; Region: GST_C_4; cd03195
1006551017040	N-terminal domain interface [polypeptide binding]; other site
1006551017041	putative dimer interface [polypeptide binding]; other site
1006551017042	putative substrate binding pocket (H-site) [chemical binding]; other site
1006551017043	GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972
1006551017044	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
1006551017045	C-terminal domain interface [polypeptide binding]; other site
1006551017046	GSH binding site (G-site) [chemical binding]; other site
1006551017047	dimer interface [polypeptide binding]; other site
1006551017048	C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291
1006551017049	N-terminal domain interface [polypeptide binding]; other site
1006551017050	putative dimer interface [polypeptide binding]; other site
1006551017051	active site
1006551017052	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
1006551017053	homooctamer interface [polypeptide binding]; other site
1006551017054	active site
1006551017055	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
1006551017056	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
1006551017057	putative NAD(P) binding site [chemical binding]; other site
1006551017058	putative active site [active]
1006551017059	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1006551017060	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1006551017061	Coenzyme A binding pocket [chemical binding]; other site
1006551017062	histidine/lysine/arginine/ornithine transporter subunit; Provisional; Region: PRK10619
1006551017063	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1006551017064	Walker A/P-loop; other site
1006551017065	ATP binding site [chemical binding]; other site
1006551017066	Q-loop/lid; other site
1006551017067	ABC transporter signature motif; other site
1006551017068	Walker B; other site
1006551017069	D-loop; other site
1006551017070	H-loop/switch region; other site
1006551017071	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1006551017072	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551017073	dimer interface [polypeptide binding]; other site
1006551017074	conserved gate region; other site
1006551017075	putative PBP binding loops; other site
1006551017076	ABC-ATPase subunit interface; other site
1006551017077	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1006551017078	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551017079	dimer interface [polypeptide binding]; other site
1006551017080	conserved gate region; other site
1006551017081	putative PBP binding loops; other site
1006551017082	ABC-ATPase subunit interface; other site
1006551017083	histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437
1006551017084	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551017085	substrate binding pocket [chemical binding]; other site
1006551017086	membrane-bound complex binding site; other site
1006551017087	hinge residues; other site
1006551017088	ABC transporter lysine/arginine/ornithine binding periplasmic protein; Provisional; Region: PRK15010
1006551017089	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551017090	substrate binding pocket [chemical binding]; other site
1006551017091	membrane-bound complex binding site; other site
1006551017092	hinge residues; other site
1006551017093	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
1006551017094	Flavoprotein; Region: Flavoprotein; pfam02441
1006551017095	amidophosphoribosyltransferase; Provisional; Region: PRK09246
1006551017096	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
1006551017097	active site
1006551017098	tetramer interface [polypeptide binding]; other site
1006551017099	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1006551017100	active site
1006551017101	colicin V production protein; Provisional; Region: PRK10845
1006551017102	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
1006551017103	cell division protein DedD; Provisional; Region: PRK11633
1006551017104	Sporulation related domain; Region: SPOR; pfam05036
1006551017105	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
1006551017106	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1006551017107	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1006551017108	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
1006551017109	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
1006551017110	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1006551017111	hypothetical protein; Provisional; Region: PRK10847
1006551017112	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
1006551017113	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1006551017114	dimerization interface 3.5A [polypeptide binding]; other site
1006551017115	active site
1006551017116	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
1006551017117	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1006551017118	erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438
1006551017119	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
1006551017120	ligand binding site [chemical binding]; other site
1006551017121	NAD binding site [chemical binding]; other site
1006551017122	catalytic site [active]
1006551017123	homodimer interface [polypeptide binding]; other site
1006551017124	flagella biosynthesis regulator; Provisional; Region: flk; PRK10715
1006551017125	putative transporter; Provisional; Region: PRK12382
1006551017126	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551017127	putative substrate translocation pore; other site
1006551017128	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
1006551017129	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1006551017130	dimer interface [polypeptide binding]; other site
1006551017131	active site
1006551017132	Uncharacterized conserved protein [Function unknown]; Region: COG4121
1006551017133	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
1006551017134	YfcL protein; Region: YfcL; pfam08891
1006551017135	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3101
1006551017136	hypothetical protein; Provisional; Region: PRK10621
1006551017137	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1006551017138	Murein endopeptidase [Cell envelope biogenesis, outer membrane]; Region: MepA; COG3770
1006551017139	penicillin-insensitive murein endopeptidase; Reviewed; Region: mepA; PRK09429
1006551017140	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
1006551017141	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
1006551017142	Tetramer interface [polypeptide binding]; other site
1006551017143	active site
1006551017144	FMN-binding site [chemical binding]; other site
1006551017145	HemK family putative methylases; Region: hemK_fam; TIGR00536
1006551017146	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1006551017147	S-adenosylmethionine binding site [chemical binding]; other site
1006551017148	hypothetical protein; Provisional; Region: PRK04946
1006551017149	Smr domain; Region: Smr; pfam01713
1006551017150	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1006551017151	catalytic core [active]
1006551017152	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
1006551017153	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1006551017154	substrate binding site [chemical binding]; other site
1006551017155	oxyanion hole (OAH) forming residues; other site
1006551017156	trimer interface [polypeptide binding]; other site
1006551017157	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1006551017158	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1006551017159	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
1006551017160	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1006551017161	dimer interface [polypeptide binding]; other site
1006551017162	active site
1006551017163	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3691
1006551017164	long-chain fatty acid outer membrane transporter; Provisional; Region: PRK10716
1006551017165	ABC transporter outer membrane lipoprotein; Provisional; Region: PRK15091
1006551017166	Formate/nitrite transporter; Region: Form_Nir_trans; cl00927
1006551017167	Formate/nitrite transporter; Region: Form_Nir_trans; cl00927
1006551017168	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
1006551017169	DNA-binding transcriptional regulator CynR; Provisional; Region: PRK11242
1006551017170	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551017171	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator CynR, contains the type 2 periplasmic binding fold; Region: PBP2_CynR; cd08425
1006551017172	dimerization interface [polypeptide binding]; other site
1006551017173	putative cyanate transporter; Provisional; Region: cynX; PRK09705
1006551017174	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551017175	aminotransferase; Validated; Region: PRK08175
1006551017176	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1006551017177	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551017178	homodimer interface [polypeptide binding]; other site
1006551017179	catalytic residue [active]
1006551017180	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
1006551017181	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
1006551017182	GAF domain; Region: GAF; pfam01590
1006551017183	Histidine kinase; Region: His_kinase; pfam06580
1006551017184	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551017185	ATP binding site [chemical binding]; other site
1006551017186	Mg2+ binding site [ion binding]; other site
1006551017187	G-X-G motif; other site
1006551017188	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1006551017189	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551017190	active site
1006551017191	phosphorylation site [posttranslational modification]
1006551017192	intermolecular recognition site; other site
1006551017193	dimerization interface [polypeptide binding]; other site
1006551017194	LytTr DNA-binding domain; Region: LytTR; pfam04397
1006551017195	glucokinase; Provisional; Region: glk; PRK00292
1006551017196	glucokinase, proteobacterial type; Region: glk; TIGR00749
1006551017197	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1006551017198	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
1006551017199	Cl- selectivity filter; other site
1006551017200	Cl- binding residues [ion binding]; other site
1006551017201	pore gating glutamate residue; other site
1006551017202	dimer interface [polypeptide binding]; other site
1006551017203	indolepyruvate decarboxylase, Erwinia family; Region: indolpyr_decarb; TIGR03393
1006551017204	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
1006551017205	dimer interface [polypeptide binding]; other site
1006551017206	PYR/PP interface [polypeptide binding]; other site
1006551017207	TPP binding site [chemical binding]; other site
1006551017208	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1006551017209	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
1006551017210	TPP-binding site [chemical binding]; other site
1006551017211	dimer interface [polypeptide binding]; other site
1006551017212	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1006551017213	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1006551017214	active site
1006551017215	catalytic tetrad [active]
1006551017216	manganese transport protein MntH; Reviewed; Region: PRK00701
1006551017217	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
1006551017218	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1006551017219	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1006551017220	Nucleoside recognition; Region: Gate; pfam07670
1006551017221	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1006551017222	MASE1; Region: MASE1; pfam05231
1006551017223	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1006551017224	Class III nucleotidyl cyclases; Region: Nucleotidyl_cyc_III; cl11967
1006551017225	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1006551017226	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
1006551017227	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
1006551017228	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
1006551017229	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1006551017230	active site
1006551017231	HIGH motif; other site
1006551017232	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1006551017233	active site
1006551017234	KMSKS motif; other site
1006551017235	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
1006551017236	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551017237	The C-terminal substrate binding domain of LysR-type transcriptional regulator XapR involved in xanthosine catabolism, contains the type 2 periplasmic binding fold; Region: PBP2_XapR; cd08449
1006551017238	putative dimerization interface [polypeptide binding]; other site
1006551017239	putative substrate binding pocket [chemical binding]; other site
1006551017240	nucleoside transporter; Region: 2A0110; TIGR00889
1006551017241	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551017242	putative substrate translocation pore; other site
1006551017243	purine nucleoside phosphorylase; Provisional; Region: PRK08202
1006551017244	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551017245	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551017246	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
1006551017247	putative dimerization interface [polypeptide binding]; other site
1006551017248	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
1006551017249	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
1006551017250	Protein of unknown function (DUF3820); Region: DUF3820; pfam12843
1006551017251	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
1006551017252	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
1006551017253	nucleotide binding pocket [chemical binding]; other site
1006551017254	K-X-D-G motif; other site
1006551017255	catalytic site [active]
1006551017256	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1006551017257	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
1006551017258	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1006551017259	Dimer interface [polypeptide binding]; other site
1006551017260	BRCT sequence motif; other site
1006551017261	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cl12038
1006551017262	cell division protein ZipA; Provisional; Region: PRK03427
1006551017263	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231
1006551017264	FtsZ protein binding site [polypeptide binding]; other site
1006551017265	putative sulfate transport protein CysZ; Validated; Region: PRK04949
1006551017266	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1006551017267	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1006551017268	dimer interface [polypeptide binding]; other site
1006551017269	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551017270	catalytic residue [active]
1006551017271	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1006551017272	dimerization domain swap beta strand [polypeptide binding]; other site
1006551017273	regulatory protein interface [polypeptide binding]; other site
1006551017274	active site
1006551017275	regulatory phosphorylation site [posttranslational modification]; other site
1006551017276	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
1006551017277	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1006551017278	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1006551017279	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1006551017280	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1006551017281	HPr interaction site; other site
1006551017282	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1006551017283	active site
1006551017284	phosphorylation site [posttranslational modification]
1006551017285	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
1006551017286	dimer interface [polypeptide binding]; other site
1006551017287	pyridoxamine kinase; Validated; Region: PRK05756
1006551017288	pyridoxal binding site [chemical binding]; other site
1006551017289	ATP binding site [chemical binding]; other site
1006551017290	transcriptional regulatory protein PtsJ; Provisional; Region: PRK15481
1006551017291	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1006551017292	DNA-binding site [nucleotide binding]; DNA binding site
1006551017293	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1006551017294	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551017295	homodimer interface [polypeptide binding]; other site
1006551017296	catalytic residue [active]
1006551017297	GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518
1006551017298	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
1006551017299	catalytic triad [active]
1006551017300	Ketosteroid isomerase homolog [Function unknown]; Region: COG4319
1006551017301	cysteine synthase B; Region: cysM; TIGR01138
1006551017302	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1006551017303	dimer interface [polypeptide binding]; other site
1006551017304	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1006551017305	catalytic residue [active]
1006551017306	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
1006551017307	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
1006551017308	Walker A/P-loop; other site
1006551017309	ATP binding site [chemical binding]; other site
1006551017310	Q-loop/lid; other site
1006551017311	ABC transporter signature motif; other site
1006551017312	Walker B; other site
1006551017313	D-loop; other site
1006551017314	H-loop/switch region; other site
1006551017315	TOBE-like domain; Region: TOBE_3; pfam12857
1006551017316	sulfate transport protein; Provisional; Region: cysT; CHL00187
1006551017317	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551017318	dimer interface [polypeptide binding]; other site
1006551017319	conserved gate region; other site
1006551017320	putative PBP binding loops; other site
1006551017321	ABC-ATPase subunit interface; other site
1006551017322	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1006551017323	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1006551017324	dimer interface [polypeptide binding]; other site
1006551017325	conserved gate region; other site
1006551017326	putative PBP binding loops; other site
1006551017327	ABC-ATPase subunit interface; other site
1006551017328	thiosulfate transporter subunit; Provisional; Region: PRK10852
1006551017329	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1006551017330	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
1006551017331	RpoE-regulated lipoprotein; Provisional; Region: PRK10718
1006551017332	Protein of unknown function (DUF1131); Region: DUF1131; pfam06572
1006551017333	Protein of unknown function (DUF2919); Region: DUF2919; pfam11143
1006551017334	putative acetyltransferase; Provisional; Region: PRK03624
1006551017335	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1006551017336	Coenzyme A binding pocket [chemical binding]; other site
1006551017337	N-acetylmuramoyl-l-alanine amidase I; Provisional; Region: PRK10319
1006551017338	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1006551017339	active site
1006551017340	metal binding site [ion binding]; metal-binding site
1006551017341	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
1006551017342	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
1006551017343	transcriptional regulator EutR; Provisional; Region: PRK10130
1006551017344	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551017345	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1006551017346	carboxysome structural protein EutK; Provisional; Region: PRK15466
1006551017347	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
1006551017348	Hexamer interface [polypeptide binding]; other site
1006551017349	Hexagonal pore residue; other site
1006551017350	ethanolamine utilization protein EutL; Provisional; Region: PRK15405
1006551017351	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_EutL_repeat1; cd07049
1006551017352	putative hexamer interface [polypeptide binding]; other site
1006551017353	putative hexagonal pore; other site
1006551017354	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_EutL_repeat2; cd07050
1006551017355	putative hexamer interface [polypeptide binding]; other site
1006551017356	putative hexagonal pore; other site
1006551017357	Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism]; Region: EutC; COG4302
1006551017358	Ethanolamine ammonia-lyase, large subunit [Amino acid transport and metabolism]; Region: EutB; COG4303
1006551017359	Ethanolamine ammonia lyase large subunit (EutB); Region: EutB; pfam06751
1006551017360	reactivating factor for ethanolamine ammonia lyase; Provisional; Region: eutA; PRK10719
1006551017361	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutH; COG3192
1006551017362	ethanol dehydrogenase EutG; Provisional; Region: PRK15454
1006551017363	iron-containing alcohol dehydrogenases (Fe-ADH)-like; Region: Fe-ADH; cd08551
1006551017364	active site
1006551017365	metal binding site [ion binding]; metal-binding site
1006551017366	potential frameshift: common BLAST hit: gi|197247829|ref|YP_002147416.1| ethanolamine utilization protein EutJ
1006551017367	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
1006551017368	putative catalytic cysteine [active]
1006551017369	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
1006551017370	Hexamer/Pentamer interface [polypeptide binding]; other site
1006551017371	central pore; other site
1006551017372	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1006551017373	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
1006551017374	Hexamer interface [polypeptide binding]; other site
1006551017375	Hexagonal pore residue; other site
1006551017376	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
1006551017377	ethanolamine utilization cobalamin adenosyltransferase; Provisional; Region: PRK15020
1006551017378	ethanolamine utilization protein EutQ; Provisional; Region: PRK15457
1006551017379	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutQ; COG4766
1006551017380	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
1006551017381	G1 box; other site
1006551017382	GTP/Mg2+ binding site [chemical binding]; other site
1006551017383	G2 box; other site
1006551017384	Switch I region; other site
1006551017385	G3 box; other site
1006551017386	Switch II region; other site
1006551017387	G4 box; other site
1006551017388	G5 box; other site
1006551017389	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
1006551017390	putative hexamer interface [polypeptide binding]; other site
1006551017391	putative hexagonal pore; other site
1006551017392	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
1006551017393	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1006551017394	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
1006551017395	putative NAD(P) binding site [chemical binding]; other site
1006551017396	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
1006551017397	transketolase; Reviewed; Region: PRK12753
1006551017398	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1006551017399	TPP-binding site [chemical binding]; other site
1006551017400	dimer interface [polypeptide binding]; other site
1006551017401	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1006551017402	PYR/PP interface [polypeptide binding]; other site
1006551017403	dimer interface [polypeptide binding]; other site
1006551017404	TPP binding site [chemical binding]; other site
1006551017405	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1006551017406	Protein of unknown function (DUF1176); Region: DUF1176; pfam06674
1006551017407	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
1006551017408	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1006551017409	dimer interface [polypeptide binding]; other site
1006551017410	ADP-ribose binding site [chemical binding]; other site
1006551017411	active site
1006551017412	nudix motif; other site
1006551017413	metal binding site [ion binding]; metal-binding site
1006551017414	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12769
1006551017415	4Fe-4S binding domain; Region: Fer4; pfam00037
1006551017416	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1006551017417	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1006551017418	aminoglycoside/multidrug efflux system; Provisional; Region: PRK10555
1006551017419	Protein export membrane protein; Region: SecD_SecF; cl14618
1006551017420	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
1006551017421	ArsC family; Region: ArsC; pfam03960
1006551017422	putative catalytic residues [active]
1006551017423	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
1006551017424	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
1006551017425	metal binding site [ion binding]; metal-binding site
1006551017426	dimer interface [polypeptide binding]; other site
1006551017427	hypothetical protein; Provisional; Region: PRK13664
1006551017428	putative hydrolase; Provisional; Region: PRK11460
1006551017429	Phospholipase/Carboxylesterase; Region: Abhydrolase_2; pfam02230
1006551017430	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
1006551017431	Helicase; Region: Helicase_RecD; pfam05127
1006551017432	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
1006551017433	Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725
1006551017434	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
1006551017435	Predicted metalloprotease [General function prediction only]; Region: COG2321
1006551017436	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
1006551017437	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
1006551017438	ATP binding site [chemical binding]; other site
1006551017439	active site
1006551017440	substrate binding site [chemical binding]; other site
1006551017441	lipoprotein; Provisional; Region: PRK11679
1006551017442	NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804
1006551017443	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1006551017444	dihydrodipicolinate synthase; Region: dapA; TIGR00674
1006551017445	dimer interface [polypeptide binding]; other site
1006551017446	active site
1006551017447	catalytic residue [active]
1006551017448	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
1006551017449	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
1006551017450	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1006551017451	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1006551017452	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
1006551017453	catalytic triad [active]
1006551017454	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1006551017455	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1006551017456	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
1006551017457	Peptidase family M48; Region: Peptidase_M48; cl12018
1006551017458	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
1006551017459	ArsC family; Region: ArsC; pfam03960
1006551017460	catalytic residues [active]
1006551017461	DNA replication initiation factor; Provisional; Region: PRK08084
1006551017462	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
1006551017463	uracil transporter; Provisional; Region: PRK10720
1006551017464	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1006551017465	active site
1006551017466	6-phospho-beta-glucosidase; Reviewed; Region: celA; PRK09589
1006551017467	beta-galactosidase; Region: BGL; TIGR03356
1006551017468	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1006551017469	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1006551017470	nucleotide binding site [chemical binding]; other site
1006551017471	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
1006551017472	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
1006551017473	dimerization interface [polypeptide binding]; other site
1006551017474	putative ATP binding site [chemical binding]; other site
1006551017475	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
1006551017476	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
1006551017477	active site
1006551017478	substrate binding site [chemical binding]; other site
1006551017479	cosubstrate binding site; other site
1006551017480	catalytic site [active]
1006551017481	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
1006551017482	Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708
1006551017483	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1006551017484	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551017485	putative substrate translocation pore; other site
1006551017486	Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins [General function prediction only]; Region: COG4225
1006551017487	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
1006551017488	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
1006551017489	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
1006551017490	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
1006551017491	putative active site [active]
1006551017492	catalytic site [active]
1006551017493	Catalytic C-terminal domain, second repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C2_like; cd09167
1006551017494	domain interface [polypeptide binding]; other site
1006551017495	active site
1006551017496	catalytic site [active]
1006551017497	exopolyphosphatase; Provisional; Region: PRK10854
1006551017498	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1006551017499	MASE1; Region: MASE1; pfam05231
1006551017500	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1006551017501	Class III nucleotidyl cyclases; Region: Nucleotidyl_cyc_III; cl11967
1006551017502	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1006551017503	Protein of unknown function (DUF2633); Region: DUF2633; pfam11119
1006551017504	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1006551017505	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1006551017506	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1006551017507	dimerization interface [polypeptide binding]; other site
1006551017508	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551017509	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1006551017510	GMP synthase; Reviewed; Region: guaA; PRK00074
1006551017511	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
1006551017512	AMP/PPi binding site [chemical binding]; other site
1006551017513	candidate oxyanion hole; other site
1006551017514	catalytic triad [active]
1006551017515	potential glutamine specificity residues [chemical binding]; other site
1006551017516	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
1006551017517	ATP Binding subdomain [chemical binding]; other site
1006551017518	Ligand Binding sites [chemical binding]; other site
1006551017519	Dimerization subdomain; other site
1006551017520	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
1006551017521	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1006551017522	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
1006551017523	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1006551017524	active site
1006551017525	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
1006551017526	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
1006551017527	generic binding surface II; other site
1006551017528	generic binding surface I; other site
1006551017529	Zinc metalloprotease (elastase) [Amino acid transport and metabolism]; Region: LasB; COG3227
1006551017530	Peptidase M4 family includes thermolysin, protealysin, aureolysin and neutral protease; Region: M4_neutral_protease; cd09597
1006551017531	active site
1006551017532	Zn binding site [ion binding]; other site
1006551017533	Protein of unknown function (DUF1407); Region: DUF1407; pfam07191
1006551017534	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1006551017535	GTP-binding protein Der; Reviewed; Region: PRK00093
1006551017536	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1006551017537	G1 box; other site
1006551017538	GTP/Mg2+ binding site [chemical binding]; other site
1006551017539	Switch I region; other site
1006551017540	G2 box; other site
1006551017541	Switch II region; other site
1006551017542	G3 box; other site
1006551017543	G4 box; other site
1006551017544	G5 box; other site
1006551017545	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1006551017546	G1 box; other site
1006551017547	GTP/Mg2+ binding site [chemical binding]; other site
1006551017548	Switch I region; other site
1006551017549	G2 box; other site
1006551017550	G3 box; other site
1006551017551	Switch II region; other site
1006551017552	G4 box; other site
1006551017553	G5 box; other site
1006551017554	outer membrane biogenesis protein BamB; Provisional; Region: PRK11138
1006551017555	Beta-barrel assembly machinery (Bam) complex component B and related proteins; Region: BamB_YfgL; cd10276
1006551017556	Trp docking motif [polypeptide binding]; other site
1006551017557	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
1006551017558	Uncharacterized protein conserved in bacteria (DUF2133); Region: DUF2133; pfam09976
1006551017559	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
1006551017560	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1006551017561	dimer interface [polypeptide binding]; other site
1006551017562	motif 1; other site
1006551017563	active site
1006551017564	motif 2; other site
1006551017565	motif 3; other site
1006551017566	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1006551017567	anticodon binding site; other site
1006551017568	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
1006551017569	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1006551017570	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1006551017571	cytoskeletal protein RodZ; Provisional; Region: PRK10856
1006551017572	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1006551017573	non-specific DNA binding site [nucleotide binding]; other site
1006551017574	salt bridge; other site
1006551017575	sequence-specific DNA binding site [nucleotide binding]; other site
1006551017576	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
1006551017577	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
1006551017578	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1006551017579	FeS/SAM binding site; other site
1006551017580	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
1006551017581	active site
1006551017582	multimer interface [polypeptide binding]; other site
1006551017583	penicillin-binding protein 1C; Provisional; Region: PRK11240
1006551017584	Transglycosylase; Region: Transgly; pfam00912
1006551017585	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1006551017586	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
1006551017587	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
1006551017588	MG2 domain; Region: A2M_N; pfam01835
1006551017589	Alpha-2-macroglobulin family; Region: A2M; pfam00207
1006551017590	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
1006551017591	surface patch; other site
1006551017592	thioester region; other site
1006551017593	specificity defining residues; other site
1006551017594	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1006551017595	M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_subfamily5; cd08019
1006551017596	metal binding site [ion binding]; metal-binding site
1006551017597	putative dimer interface [polypeptide binding]; other site
1006551017598	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
1006551017599	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
1006551017600	active site residue [active]
1006551017601	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
1006551017602	active site residue [active]
1006551017603	enhanced serine sensitivity protein SseB; Provisional; Region: PRK11611
1006551017604	aminopeptidase B; Provisional; Region: PRK05015
1006551017605	Peptidase; Region: DUF3663; pfam12404
1006551017606	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1006551017607	interface (dimer of trimers) [polypeptide binding]; other site
1006551017608	Substrate-binding/catalytic site; other site
1006551017609	Zn-binding sites [ion binding]; other site
1006551017610	hypothetical protein; Provisional; Region: PRK10721
1006551017611	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1006551017612	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1006551017613	catalytic loop [active]
1006551017614	iron binding site [ion binding]; other site
1006551017615	chaperone protein HscA; Provisional; Region: hscA; PRK05183
1006551017616	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
1006551017617	nucleotide binding site [chemical binding]; other site
1006551017618	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1006551017619	SBD interface [polypeptide binding]; other site
1006551017620	co-chaperone HscB; Provisional; Region: hscB; PRK05014
1006551017621	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1006551017622	HSP70 interaction site [polypeptide binding]; other site
1006551017623	HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743
1006551017624	iron-sulfur cluster assembly protein; Provisional; Region: iscA; PRK09502
1006551017625	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
1006551017626	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
1006551017627	trimerization site [polypeptide binding]; other site
1006551017628	active site
1006551017629	cysteine desulfurase; Provisional; Region: PRK14012
1006551017630	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1006551017631	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1006551017632	catalytic residue [active]
1006551017633	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
1006551017634	Rrf2 family protein; Region: rrf2_super; TIGR00738
1006551017635	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
1006551017636	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
1006551017637	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1006551017638	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
1006551017639	active site
1006551017640	dimerization interface [polypeptide binding]; other site
1006551017641	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1006551017642	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG2215
1006551017643	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG3683
1006551017644	stationary phase inducible protein CsiE; Provisional; Region: PRK11564
1006551017645	PRD domain; Region: PRD; pfam00874
1006551017646	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
1006551017647	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551017648	putative substrate translocation pore; other site
1006551017649	aldose 1-epimerase, similar to Escherichia coli YphB; Region: Aldose_epim_Ec_YphB; cd09021
1006551017650	active site
1006551017651	catalytic residues [active]
1006551017652	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
1006551017653	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551017654	putative substrate translocation pore; other site
1006551017655	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551017656	TPR repeat; Region: TPR_11; pfam13414
1006551017657	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1006551017658	binding surface
1006551017659	TPR repeat; Region: TPR_11; pfam13414
1006551017660	TPR motif; other site
1006551017661	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
1006551017662	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1006551017663	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1006551017664	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1006551017665	Predicted membrane protein [Function unknown]; Region: COG2259
1006551017666	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
1006551017667	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1006551017668	dimer interface [polypeptide binding]; other site
1006551017669	active site
1006551017670	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1006551017671	folate binding site [chemical binding]; other site
1006551017672	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
1006551017673	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
1006551017674	heme-binding site [chemical binding]; other site
1006551017675	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
1006551017676	FAD binding pocket [chemical binding]; other site
1006551017677	FAD binding motif [chemical binding]; other site
1006551017678	phosphate binding motif [ion binding]; other site
1006551017679	beta-alpha-beta structure motif; other site
1006551017680	NAD binding pocket [chemical binding]; other site
1006551017681	Heme binding  pocket [chemical binding]; other site
1006551017682	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
1006551017683	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cl17402
1006551017684	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1006551017685	dimerization interface [polypeptide binding]; other site
1006551017686	ligand binding site [chemical binding]; other site
1006551017687	Ureidoglycolate hydrolase; Region: Ureidogly_hydro; cl01250
1006551017688	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
1006551017689	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1006551017690	substrate binding site [chemical binding]; other site
1006551017691	ATP binding site [chemical binding]; other site
1006551017692	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
1006551017693	L-fucose transporter; Provisional; Region: PRK10133; cl17665
1006551017694	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
1006551017695	active site
1006551017696	intersubunit interactions; other site
1006551017697	catalytic residue [active]
1006551017698	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1006551017699	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
1006551017700	dimer interface [polypeptide binding]; other site
1006551017701	active site
1006551017702	metal binding site [ion binding]; metal-binding site
1006551017703	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
1006551017704	Nitrogen regulatory protein P-II; Region: P-II; smart00938
1006551017705	response regulator GlrR; Provisional; Region: PRK15115
1006551017706	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1006551017707	active site
1006551017708	phosphorylation site [posttranslational modification]
1006551017709	intermolecular recognition site; other site
1006551017710	dimerization interface [polypeptide binding]; other site
1006551017711	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1006551017712	Walker A motif; other site
1006551017713	ATP binding site [chemical binding]; other site
1006551017714	Walker B motif; other site
1006551017715	arginine finger; other site
1006551017716	hypothetical protein; Provisional; Region: PRK10722
1006551017717	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1006551017718	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1006551017719	dimer interface [polypeptide binding]; other site
1006551017720	phosphorylation site [posttranslational modification]
1006551017721	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1006551017722	ATP binding site [chemical binding]; other site
1006551017723	Mg2+ binding site [ion binding]; other site
1006551017724	G-X-G motif; other site
1006551017725	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
1006551017726	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
1006551017727	dimerization interface [polypeptide binding]; other site
1006551017728	ATP binding site [chemical binding]; other site
1006551017729	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
1006551017730	dimerization interface [polypeptide binding]; other site
1006551017731	ATP binding site [chemical binding]; other site
1006551017732	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
1006551017733	putative active site [active]
1006551017734	catalytic triad [active]
1006551017735	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
1006551017736	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1006551017737	substrate binding pocket [chemical binding]; other site
1006551017738	membrane-bound complex binding site; other site
1006551017739	hinge residues; other site
1006551017740	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1006551017741	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1006551017742	catalytic residue [active]
1006551017743	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1006551017744	nucleoside/Zn binding site; other site
1006551017745	dimer interface [polypeptide binding]; other site
1006551017746	catalytic motif [active]
1006551017747	hypothetical protein; Provisional; Region: PRK11590
1006551017748	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
1006551017749	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1006551017750	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11557
1006551017751	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1006551017752	putative active site [active]
1006551017753	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1006551017754	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
1006551017755	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
1006551017756	active site
1006551017757	hydrophilic channel; other site
1006551017758	dimerization interface [polypeptide binding]; other site
1006551017759	catalytic residues [active]
1006551017760	active site lid [active]
1006551017761	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
1006551017762	Recombination protein O N terminal; Region: RecO_N; pfam11967
1006551017763	Recombination protein O C terminal; Region: RecO_C; pfam02565
1006551017764	GTPase Era; Reviewed; Region: era; PRK00089
1006551017765	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
1006551017766	G1 box; other site
1006551017767	GTP/Mg2+ binding site [chemical binding]; other site
1006551017768	Switch I region; other site
1006551017769	G2 box; other site
1006551017770	Switch II region; other site
1006551017771	G3 box; other site
1006551017772	G4 box; other site
1006551017773	G5 box; other site
1006551017774	KH domain; Region: KH_2; pfam07650
1006551017775	ribonuclease III; Reviewed; Region: rnc; PRK00102
1006551017776	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1006551017777	dimerization interface [polypeptide binding]; other site
1006551017778	active site
1006551017779	metal binding site [ion binding]; metal-binding site
1006551017780	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1006551017781	dsRNA binding site [nucleotide binding]; other site
1006551017782	signal peptidase I; Provisional; Region: PRK10861
1006551017783	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1006551017784	Catalytic site [active]
1006551017785	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1006551017786	GTP-binding protein LepA; Provisional; Region: PRK05433
1006551017787	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1006551017788	G1 box; other site
1006551017789	putative GEF interaction site [polypeptide binding]; other site
1006551017790	GTP/Mg2+ binding site [chemical binding]; other site
1006551017791	Switch I region; other site
1006551017792	G2 box; other site
1006551017793	G3 box; other site
1006551017794	Switch II region; other site
1006551017795	G4 box; other site
1006551017796	G5 box; other site
1006551017797	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
1006551017798	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1006551017799	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1006551017800	SoxR reducing system protein RseC; Provisional; Region: PRK10862
1006551017801	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026
1006551017802	anti-sigma E factor; Provisional; Region: rseB; PRK09455
1006551017803	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
1006551017804	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
1006551017805	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
1006551017806	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
1006551017807	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1006551017808	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1006551017809	DNA binding residues [nucleotide binding]
1006551017810	L-aspartate oxidase; Provisional; Region: PRK09077
1006551017811	L-aspartate oxidase; Provisional; Region: PRK06175
1006551017812	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1006551017813	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
1006551017814	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1006551017815	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
1006551017816	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1006551017817	ATP binding site [chemical binding]; other site
1006551017818	Mg++ binding site [ion binding]; other site
1006551017819	motif III; other site
1006551017820	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1006551017821	nucleotide binding region [chemical binding]; other site
1006551017822	ATP-binding site [chemical binding]; other site
1006551017823	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
1006551017824	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
1006551017825	ligand binding site [chemical binding]; other site
1006551017826	active site
1006551017827	UGI interface [polypeptide binding]; other site
1006551017828	catalytic site [active]
1006551017829	putative methyltransferase; Provisional; Region: PRK10864
1006551017830	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
1006551017831	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1006551017832	thioredoxin 2; Provisional; Region: PRK10996
1006551017833	zinc-ribbon domain; Region: zinc_ribbon_5; cl11777
1006551017834	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1006551017835	catalytic residues [active]
1006551017836	Uncharacterized conserved protein [Function unknown]; Region: COG3148
1006551017837	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
1006551017838	CoA binding domain; Region: CoA_binding_2; pfam13380
1006551017839	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
1006551017840	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
1006551017841	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1006551017842	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1006551017843	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
1006551017844	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
1006551017845	domain interface [polypeptide binding]; other site
1006551017846	putative active site [active]
1006551017847	catalytic site [active]
1006551017848	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
1006551017849	domain interface [polypeptide binding]; other site
1006551017850	putative active site [active]
1006551017851	catalytic site [active]
1006551017852	lipoprotein; Provisional; Region: PRK10759
1006551017853	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
1006551017854	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1006551017855	putative substrate translocation pore; other site
1006551017856	Domain of unknown function (DUF4385); Region: DUF4385; pfam14328