-- dump date 20140619_121605 -- class Genbank::CDS -- table cds_note -- id note YP_001687854.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space YP_001687862.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor regulates the genes for iron dicitrate transport YP_001687904.1 similar protein in Methanocaldococcus converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate as the first step in methanopterin biosynthesis YP_001687910.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides YP_001687911.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_001687915.1 IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats YP_001687954.1 with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver YP_001687956.1 with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver YP_001687957.1 response regulator in two-component regulatory system with CusS; regulates the copper efflux system YP_001687990.1 SopB YP_001688099.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001688101.1 PliC; periplasmic lysozyme inhibitor of c-type lysozyme YP_002916991.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_002916992.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase YP_002916993.1 catalyzes the formation of asparagine from aspartate and ammonia YP_002916994.1 contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA YP_002916995.1 interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase YP_002916996.1 Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH YP_002916997.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source YP_002916998.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain YP_002916999.1 functions to transport ribose at high affinity; forms a complex with RbsA2C2B YP_002917000.1 periplasmic substrate-binding component of the ATP-dependent ribose transport system YP_002917001.1 catalyzes the formation of D-ribose 5-phosphate from ribose YP_002917002.1 DNA-binding transcriptional repressor of ribose metabolism YP_002917003.1 internal ID: KP0013 YP_002917004.1 internal ID: KP0014 YP_002917005.1 in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway YP_002917006.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis YP_002917007.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0018 YP_002917008.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0019 YP_002917009.1 internal ID: KP0022 YP_002917010.1 internal ID: KP0023 YP_002917011.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_002917012.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_002917013.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0026 YP_002917014.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_002917015.1 response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54 YP_002917016.1 sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation YP_002917017.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme YP_002917018.1 internal ID: KP0031 YP_002917019.1 internal ID: KP0032 YP_002917020.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease YP_002917021.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_002917022.1 internal ID: KP0035 YP_002917023.1 internal ID: KP0036 YP_002917024.1 internal ID: KP0037 YP_002917025.1 internal ID: KP0038 YP_002917026.1 required for the formation of active formate dehydrogenase YP_002917027.1 cytochrome b556(FDO) component; heme containing YP_002917028.1 internal ID: KP0041 YP_002917029.1 internal ID: KP0043 YP_002917030.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth YP_002917031.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0047 YP_002917032.1 identified by Glimmer2; internal ID: KP0048 YP_002917033.1 identified by Glimmer2; internal ID: KP0049 YP_002917034.1 internal ID: KP0050 YP_002917035.1 internal ID: KP0051 YP_002917036.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr YP_002917037.1 internal ID: KP0053 YP_002917038.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0054 YP_002917039.1 internal ID: KP0055 YP_002917040.1 internal ID: KP0056 YP_002917041.1 internal ID: KP0057 YP_002917042.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0058 YP_002917043.1 internal ID: KP0059 YP_002917044.1 internal ID: KP0061 YP_002917045.1 internal ID: KP0062 YP_002917046.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments YP_002917047.1 internal ID: KP0064 YP_002917048.1 internal ID: KP0065 YP_002917049.1 internal ID: KP0066 YP_002917050.1 internal ID: KP0067 YP_002917051.1 internal ID: KP0068 YP_002917052.1 internal ID: KP0069 YP_002917053.1 internal ID: KP0070 YP_002917054.1 catalyzes the formation of L-rhamnulose from L-rhamnose YP_002917055.1 catalyzes the ATP-dependent phosphorylation of rhamnulose YP_002917056.1 activates the expression of the rhaBAD operon and rhaT gene YP_002917057.1 internal ID: KP0074 YP_002917058.1 transports L-rhamnose and L-lyxose into the cell YP_002917059.1 SodA; manganese binding; only present under aerobic conditions; destroys free radicals YP_002917060.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0077 YP_002917061.1 part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors YP_002917062.1 response regulator in two-component regulatory system with CpxA; part of the envelope stress response system YP_002917063.1 repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates YP_002917064.1 member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers YP_002917065.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis YP_002917066.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_002917067.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate YP_002917068.1 heat shock protein involved in degradation of misfolded proteins YP_002917069.1 heat shock protein involved in degradation of misfolded proteins YP_002917070.1 internal ID: KP0090 YP_002917071.1 negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins YP_002917072.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_002917073.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_002917074.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis YP_002917075.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine YP_002917076.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_002917077.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0097 YP_002917078.1 internal ID: KP0099 YP_002917079.1 internal ID: KP0100 YP_002917080.1 internal ID: KP0101 YP_002917081.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor YP_002917082.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0103 YP_002917083.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone YP_002917084.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies YP_002917085.1 internal ID: KP0106 YP_002917086.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0107 YP_002917087.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_002917088.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis YP_002917089.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_002917090.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_002917091.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_002917092.1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA YP_002917093.1 catalyzes the conversion of NADPH to NADH YP_002917094.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis YP_002917095.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0118 YP_002917096.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs YP_002917097.1 identified by GeneMark.hmm; internal ID: KP0120 YP_002917098.1 involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space YP_002917099.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_002917100.1 Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon YP_002917101.1 internal ID: KP0125 YP_002917102.1 internal ID: KP0126 YP_002917103.1 identified by Glimmer2; internal ID: KP0127 YP_002917104.1 identified by Glimmer2; internal ID: KP0128 YP_002917105.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_002917106.1 internal ID: KP0130 YP_002917107.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_002917108.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_002917109.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway YP_002917110.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate YP_002917111.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_002917112.1 internal ID: KP0136 YP_002917113.1 internal ID: KP0137 YP_002917114.1 single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication YP_002917115.1 internal ID: KP0139 YP_002917116.1 internal ID: KP0140 YP_002917117.1 internal ID: KP0141 YP_002917118.1 catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation YP_002917119.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation YP_002917120.1 internal ID: KP0144 YP_002917121.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_002917122.1 internal ID: KP0146 YP_002917123.1 Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein YP_002917124.1 internal ID: KP0148 YP_002917125.1 catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid YP_002917126.1 internal ID: KP0150 YP_002917127.1 internal ID: KP0151 YP_002917128.1 internal ID: KP0152 YP_002917129.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis YP_002917130.1 internal ID: KP0154 YP_002917131.1 catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis YP_002917132.1 enterobacterial common antigen polymerase YP_002917133.1 internal ID: KP0157 YP_002917134.1 uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function YP_002917135.1 identified by Glimmer2; internal ID: KP0159 YP_002917136.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0160 YP_002917137.1 internal ID: KP0161 YP_002917138.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis YP_002917139.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_002917140.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP YP_002917141.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly YP_002917142.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0167 YP_002917143.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_002917144.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0169 YP_002917145.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_002917146.1 YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function YP_002917147.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. YP_002917148.1 responsible for the influx of magnesium ions YP_002917149.1 internal ID: KP0174 YP_002917150.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0176 YP_002917151.1 catalyzes the hydrolysis of phosphatidylcholine YP_002917152.1 functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway YP_002917153.1 internal ID: KP0179 YP_002917154.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0180 YP_002917155.1 internal ID: KP0181 YP_002917156.1 lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates YP_002917157.1 purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium YP_002917158.1 internal ID: KP0184 YP_002917159.1 internal ID: KP0185 YP_002917160.1 identified by Glimmer2; internal ID: KP0186 YP_002917161.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_002917162.1 internal ID: KP0188 YP_002917163.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway YP_002917164.1 YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner YP_002917165.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone YP_002917166.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0193 YP_002917167.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions YP_002917168.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_002917169.1 mediates the export of protein precursors bearing twin-arginine signal peptides YP_002917170.1 with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane YP_002917171.1 magnesium dependent; not involved in the Sec-independent protein export system YP_002917172.1 internal ID: KP0199 YP_002917173.1 catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol YP_002917174.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin YP_002917175.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_002917176.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_002917177.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters YP_002917178.1 internal ID: KP0205 YP_002917179.1 internal ID: KP0206 YP_002917180.1 catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX YP_002917181.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_002917182.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon YP_002917183.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_002917184.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_002917185.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_002917186.1 Modulates Rho-dependent transcription termination YP_002917187.1 binds directly to 23S ribosomal RNA YP_002917188.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_002917189.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_002917190.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_002917191.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_002917192.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_002917193.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters YP_002917194.1 internal ID: KP0225 YP_002917195.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0226 YP_002917196.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0227 YP_002917197.1 identified by Glimmer2; internal ID: KP0228 YP_002917198.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center YP_002917199.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_002917200.1 internal ID: KP0231 YP_002917201.1 internal ID: KP0232 YP_002917202.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate YP_002917203.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_002917204.1 binds specifically to the major sigma factor sigma 70; active in stationary phase YP_002917205.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates YP_002917206.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_002917207.1 Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures YP_002917208.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0239 YP_002917209.1 histone-like DNA-binding protein YP_002917210.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0242 YP_002917211.1 internal ID: KP0243 YP_002917212.1 identified by Glimmer2; internal ID: KP0244 YP_002917213.1 internal ID: KP0245 YP_002917214.1 DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein YP_002917215.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_002917216.1 involved in de novo purine biosynthesis YP_002917217.1 internal ID: KP0250 YP_002917218.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis YP_002917219.1 identified by Glimmer2; internal ID: KP0252 YP_002917220.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_002917221.1 internal ID: KP0254 YP_002917222.1 catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol YP_002917223.1 regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase YP_002917224.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity YP_002917225.1 internal ID: KP0258 YP_002917226.1 alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family YP_002917227.1 catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA YP_002917228.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0261 YP_002917229.1 internal ID: KP0262 YP_002917230.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive YP_002917231.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_002917232.1 internal ID: KP0265 YP_002917233.1 internal ID: KP0267 YP_002917234.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0268 YP_002917235.1 internal ID: KP0269 YP_002917236.1 internal ID: KP0270 YP_002917237.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0271 YP_002917238.1 internal ID: KP0272 YP_002917239.1 with MalKFE is involved in the transport of maltose into the cell YP_002917240.1 with MalKGE is involved in maltose transport into the cell YP_002917241.1 functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis YP_002917242.1 with malEFG is involved in import of maltose/maltodextrin YP_002917243.1 porin involved in the transport of maltose and maltodextrins YP_002917244.1 internal ID: KP0278 YP_002917245.1 internal ID: KP0279 YP_002917246.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway YP_002917247.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA YP_002917248.1 internal ID: KP0282 YP_002917249.1 Represses a number of genes involved in the response to DNA damage YP_002917250.1 internal ID: KP0284 YP_002917251.1 identified by Glimmer2; internal ID: KP0285 YP_002917252.1 unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential YP_002917253.1 Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB YP_002917254.1 identified by Glimmer2; internal ID: KP0288 YP_002917255.1 internal ID: KP0289 YP_002917256.1 internal ID: KP0290 YP_002917257.1 coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia YP_002917258.1 internal ID: KP0293 YP_002917259.1 unwinds double stranded DNA YP_002917260.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_002917261.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_002917262.1 Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity YP_002917263.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0299 YP_002917264.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0300 YP_002917265.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_002917266.1 binds to single stranded DNA and PriA helcase facilitate replication restart YP_002917267.1 internal ID: KP0303 YP_002917268.1 identified by Glimmer2; internal ID: KP0304 YP_002917269.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space YP_002917270.1 internal ID: KP0307 YP_002917271.1 internal ID: KP0308 YP_002917272.1 internal ID: KP0309 YP_002917273.1 internal ID: KP0311 YP_002917274.1 part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins YP_002917275.1 identified by Glimmer2; internal ID: KP0313 YP_002917276.1 internal ID: KP0314 YP_002917277.1 internal ID: KP0315 YP_002917278.1 internal ID: KP0316 YP_002917279.1 internal ID: KP0317 YP_002917280.1 internal ID: KP0319 YP_002917281.1 internal ID: KP0320 YP_002917282.1 internal ID: KP0321 YP_002917283.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0322 YP_002917284.1 identified by Glimmer2; internal ID: KP0323 YP_002917285.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0324 YP_002917286.1 regulates genes involved in response to oxidative stress YP_002917287.1 internal ID: KP0326 YP_002917288.1 internal ID: KP0327 YP_002917289.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0328 YP_002917290.1 internal ID: KP0329 YP_002917291.1 internal ID: KP0330 YP_002917292.1 internal ID: KP0331 YP_002917293.1 internal ID: KP0332 YP_002917294.1 internal ID: KP0334 YP_002917295.1 internal ID: KP0335 YP_002917296.1 internal ID: KP0336 YP_002917297.1 internal ID: KP0337 YP_002917298.1 internal ID: KP0338 YP_002917299.1 member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake YP_002917300.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0341 YP_002917301.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_002917302.1 identified by Glimmer2; internal ID: KP0343 YP_002917303.1 carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system YP_002917304.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0345 YP_002917305.1 internal ID: KP0346 YP_002917306.1 internal ID: KP0348 YP_002917307.1 internal ID: KP0349 YP_002917308.1 internal ID: KP0351 YP_002917309.1 internal ID: KP0352 YP_002917310.1 internal ID: KP0353 YP_002917311.1 internal ID: KP0354 YP_002917312.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0355 YP_002917313.1 required for the use of phosphonates and phosphite as phosphorus sources YP_002917314.1 internal ID: KP0357 YP_002917315.1 internal ID: KP0358 YP_002917316.1 internal ID: KP0359 YP_002917317.1 internal ID: KP0360 YP_002917318.1 internal ID: KP0362 YP_002917319.1 internal ID: KP0363 YP_002917320.1 internal ID: KP0364 YP_002917321.1 internal ID: KP0365 YP_002917322.1 may be involved in phosphonate uptake and biodegradation YP_002917323.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0367 YP_002917324.1 internal ID: KP0368 YP_002917325.1 internal ID: KP0369 YP_002917326.1 internal ID: KP0370 YP_002917327.1 internal ID: KP0371 YP_002917328.1 internal ID: KP0372 YP_002917329.1 internal ID: KP0373 YP_002917330.1 internal ID: KP0374 YP_002917331.1 with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA YP_002917332.1 functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock YP_002917333.1 internal ID: KP0378 YP_002917334.1 internal ID: KP0379 YP_002917335.1 in Yersinia this gene is involved in biofilm formation and hemin adsorption YP_002917336.1 predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein YP_002917337.1 in Yersinia this protein is involved in biofilm formation and hemin adsorption; related protein PgaB in Escherichia coli is an outer membrane N-deacetylase involved in poly-beta-1,6-N-acetyl-D-glucosamine (PGA) export YP_002917338.1 outer membrane protein essential for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine (PGA); adhesin required for biofilm formation; PgaA (HmsH) seems to translocate and/or dock PGA to the cell surface; member of the hmsHFRS (ycdSRQP or pgaABCD in Escherichia coli) operon in Yersinia YP_002917339.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0384 YP_002917340.1 identified by GeneMark and GeneMark.hmm; internal ID: KP0385 YP_002917341.1 identified by GeneMark.hmm; internal ID: KP0386 YP_002917342.1 identified by GeneMark.hmm; internal ID: KP0387 YP_002917343.1 identified by GeneMark.hmm; internal ID: KP0388 YP_002917344.1 identified by GeneMark.hmm; internal ID: KP0389 YP_002917345.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0390 YP_002917346.1 internal ID: KP0391 YP_002917347.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm YP_002917348.1 copper binding protein required for copper tolerance; involved in resistance toward heavy metals YP_002917349.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB YP_002917350.1 catalyzes the formation of fumarate from aspartate YP_002917351.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein YP_002917352.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function YP_002917353.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_002917354.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_002917355.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0401 YP_002917356.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0402 YP_002917357.1 internal ID: KP0403 YP_002917358.1 internal ID: KP0404 YP_002917359.1 identified by GeneMark.hmm; internal ID: KP0406 YP_002917360.1 identified by Glimmer2; internal ID: KP0408 YP_002917361.1 internal ID: KP0409 YP_002917362.1 internal ID: KP0410 YP_002917363.1 internal ID: KP0411 YP_002917364.1 internal ID: KP0412 YP_002917365.1 internal ID: KP0413 YP_002917366.1 identified by Glimmer2; internal ID: KP0415 YP_002917367.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_002917368.1 internal ID: KP0418 YP_002917369.1 internal ID: KP0419 YP_002917370.1 internal ID: KP0420 YP_002917371.1 lipocalin; globomycin-sensitive outer membrane lipoprotein YP_002917372.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane YP_002917373.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_002917374.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_002917375.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_002917376.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_002917377.1 internal ID: KP0427 YP_002917378.1 internal ID: KP0428 YP_002917379.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine YP_002917380.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_002917381.1 3'-5' exoribonuclease specific for small oligoribonuclotides YP_002917382.1 internal ID: KP0432 YP_002917383.1 identified by Glimmer2; internal ID: KP0433 YP_002917384.1 internal ID: KP0434 YP_002917385.1 internal ID: KP0435 YP_002917386.1 possibly involved in cell wall synthesis YP_002917387.1 internal ID: KP0437 YP_002917388.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_002917389.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_002917390.1 Stimulates the elongation of poly(A) tails YP_002917391.1 involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein YP_002917392.1 with HflC inhibits proteolysis of lambda cII protein by FtsH YP_002917393.1 with HflK inhibits proteolysis of lambda cII protein by FtsH YP_002917394.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0445 YP_002917395.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0446 YP_002917396.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_002917397.1 negatively regulates the transcription of genes upregulated by nitrosative stress YP_002917398.1 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs YP_002917399.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA YP_002917400.1 catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA YP_002917401.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0453 YP_002917402.1 in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility YP_002917403.1 YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo YP_002917404.1 negative regulator of ulaG and ulaABCDEF YP_002917405.1 internal ID: KP0458 YP_002917406.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr YP_002917407.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_002917408.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_002917409.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization YP_002917410.1 UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway YP_002917411.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_002917412.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0466 YP_002917413.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0467 YP_002917414.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_002917415.1 internal ID: KP0469 YP_002917416.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_002917417.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_002917418.1 internal ID: KP0473 YP_002917419.1 FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides YP_002917420.1 involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine YP_002917421.1 Involved in anaerobic NO protection and iron metabolism YP_002917422.1 internal ID: KP0478 YP_002917423.1 internal ID: KP0479 YP_002917424.1 internal ID: KP0481 YP_002917425.1 internal ID: KP0482 YP_002917426.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate YP_002917427.1 catalyzes the formation of AMP from adenosine-3',5'-bisphosphate YP_002917428.1 internal ID: KP0485 YP_002917429.1 internal ID: KP0486 YP_002917430.1 internal ID: KP0487 YP_002917431.1 internal ID: KP0488 YP_002917432.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress YP_002917433.1 internal ID: KP0490 YP_002917434.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0491 YP_002917435.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0492 YP_002917436.1 identified by Glimmer2; internal ID: KP0493 YP_002917437.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_002917438.1 internal ID: KP0495 YP_002917439.1 internal ID: KP0496 YP_002917440.1 internal ID: KP0497 YP_002917441.1 membrane component of a putative sugar ABC transporter system YP_002917442.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate YP_002917443.1 identified by Glimmer2; internal ID: KP0500 YP_002917444.1 internal ID: KP0501 YP_002917445.1 internal ID: KP0502 YP_002917446.1 internal ID: KP0503 YP_002917447.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0504 YP_002917448.1 protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD YP_002917449.1 internal ID: KP0506 YP_002917450.1 internal ID: KP0509 YP_002917451.1 internal ID: KP0510 YP_002917452.1 internal ID: KP0511 YP_002917453.1 internal ID: KP0512 YP_002917454.1 internal ID: KP0513 YP_002917455.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides YP_002917456.1 internal ID: KP0515 YP_002917457.1 identified by Glimmer2; internal ID: KP0516 YP_002917458.1 internal ID: KP0517 YP_002917459.1 internal ID: KP0518 YP_002917460.1 internal ID: KP0519 YP_002917461.1 Qin prophage; bifunctional antitoxin of the RelE-RelB toxin-antitoxin system/transcriptional repressor YP_002917462.1 internal ID: KP0521 YP_002917463.1 activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions YP_002917464.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_002917465.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0526 YP_002917466.1 internal ID: KP0527 YP_002917467.1 internal ID: KP0528 YP_002917468.1 internal ID: KP0529 YP_002917469.1 internal ID: KP0530 YP_002917470.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002917471.1 regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon YP_002917472.1 P-type ATPase involved in magnesium influx YP_002917473.1 internal ID: KP0534 YP_002917474.1 involved in the allosteric regulation of aspartate carbamoyltransferase YP_002917475.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_002917476.1 internal ID: KP0538 YP_002917477.1 internal ID: KP0539 YP_002917478.1 internal ID: KP0540 YP_002917479.1 internal ID: KP0542 YP_002917480.1 internal ID: KP0543 YP_002917481.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_002917482.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_002917483.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_002917484.1 internal ID: KP0548 YP_002917485.1 internal ID: KP0549 YP_002917486.1 internal ID: KP0550 YP_002917487.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0551 YP_002917488.1 internal ID: KP0552 YP_002917489.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0553 YP_002917490.1 internal ID: KP0557 YP_002917491.1 internal ID: KP0558 YP_002917492.1 internal ID: KP0559 YP_002917493.1 internal ID: KP0560 YP_002917494.1 internal ID: KP0562 YP_002917495.1 internal ID: KP0564 YP_002917496.1 internal ID: KP0565 YP_002917497.1 internal ID: KP0566 YP_002917498.1 internal ID: KP0567 YP_002917499.1 internal ID: KP0568 YP_002917500.1 internal ID: KP0569 YP_002917501.1 internal ID: KP0570 YP_002917502.1 internal ID: KP0571 YP_002917503.1 internal ID: KP0572 YP_002917504.1 internal ID: KP0573 YP_002917505.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0574 YP_002917506.1 identified by GeneMark.hmm; internal ID: KP0575 YP_002917507.1 identified by Glimmer2; internal ID: KP0576 YP_002917508.1 internal ID: KP0577 YP_002917509.1 internal ID: KP0578 YP_002917510.1 internal ID: KP0580 YP_002917511.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0581 YP_002917512.1 internal ID: KP0583 YP_002917513.1 identified by Glimmer2; internal ID: KP0585 YP_002917514.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0586 YP_002917515.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0587 YP_002917516.1 identified by GeneMark.hmm; internal ID: KP0588 YP_002917517.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0589 YP_002917518.1 internal ID: KP0590 YP_002917519.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0591 YP_002917520.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0592 YP_002917521.1 internal ID: KP0593 YP_002917522.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0594 YP_002917523.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0595 YP_002917524.1 internal ID: KP0596 YP_002917525.1 internal ID: KP0597 YP_002917526.1 internal ID: KP0598 YP_002917527.1 internal ID: KP0600 YP_002917528.1 internal ID: KP0601 YP_002917529.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0602 YP_002917530.1 internal ID: KP0604 YP_002917531.1 internal ID: KP0605 YP_002917532.1 internal ID: KP0607 YP_002917533.1 internal ID: KP0608 YP_002917534.1 internal ID: KP0609 YP_002917535.1 internal ID: KP0611 YP_002917536.1 internal ID: KP0612 YP_002917537.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0613 YP_002917538.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0614 YP_002917539.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0615 YP_002917540.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0616 YP_002917541.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0617 YP_002917542.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0618 YP_002917543.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0619 YP_002917544.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0620 YP_002917545.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0621 YP_002917546.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0622 YP_002917547.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0623 YP_002917548.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0625 YP_002917549.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0626 YP_002917550.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0627 YP_002917551.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0628 YP_002917552.1 internal ID: KP0629 YP_002917553.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0630 YP_002917554.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0631 YP_002917555.1 identified by Glimmer2; internal ID: KP0632 YP_002917556.1 internal ID: KP0633 YP_002917557.1 internal ID: KP0634 YP_002917558.1 internal ID: KP0635 YP_002917559.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0636 YP_002917560.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0637 YP_002917561.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0638 YP_002917562.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0639 YP_002917563.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0640 YP_002917564.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0641 YP_002917565.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0642 YP_002917566.1 internal ID: KP0644 YP_002917567.1 internal ID: KP0645 YP_002917568.1 internal ID: KP0646 YP_002917569.1 internal ID: KP0647 YP_002917570.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0649 YP_002917571.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0650 YP_002917572.1 internal ID: KP0651 YP_002917573.1 internal ID: KP0653 YP_002917574.1 internal ID: KP0654 YP_002917575.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0655 YP_002917576.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0656 YP_002917577.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0658 YP_002917578.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0660 YP_002917579.1 internal ID: KP0661 YP_002917580.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0662 YP_002917581.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0663 YP_002917582.1 internal ID: KP0664 YP_002917583.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0666 YP_002917584.1 internal ID: KP0667 YP_002917585.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0668 YP_002917586.1 catalyzes the interconversion of D-xylose to D-xylulose YP_002917587.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0670 YP_002917588.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0672 YP_002917589.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0673 YP_002917590.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0674 YP_002917591.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0675 YP_002917592.1 internal ID: KP0677 YP_002917593.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0678 YP_002917594.1 internal ID: KP0679 YP_002917595.1 internal ID: KP0680 YP_002917596.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0681 YP_002917597.1 identified by GeneMark.hmm; internal ID: KP0682 YP_002917598.1 internal ID: KP0683 YP_002917599.1 lipocalin; globomycin-sensitive outer membrane lipoprotein YP_002917600.1 internal ID: KP0685 YP_002917601.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0686 YP_002917602.1 with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver YP_002917603.1 internal ID: KP0688 YP_002917604.1 with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver YP_002917605.1 response regulator in two-component regulatory system with CusS; regulates the copper efflux system YP_002917606.1 internal ID: KP0691 YP_002917607.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0692 YP_002917608.1 internal ID: KP0693 YP_002917609.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0694 YP_002917610.1 identified by Glimmer2; internal ID: KP0696 YP_002917611.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0697 YP_002917612.1 internal ID: KP0698 YP_002917613.1 internal ID: KP0699 YP_002917614.1 internal ID: KP0700 YP_002917615.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002917616.1 internal ID: KP0702 YP_002917617.1 internal ID: KP0703 YP_002917618.1 internal ID: KP0704 YP_002917619.1 internal ID: KP0705 YP_002917620.1 internal ID: KP0706 YP_002917621.1 internal ID: KP0707 YP_002917622.1 internal ID: KP0708 YP_002917623.1 internal ID: KP0709 YP_002917624.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0710 YP_002917625.1 internal ID: KP0711 YP_002917626.1 internal ID: KP0713 YP_002917627.1 internal ID: KP0714 YP_002917628.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0715 YP_002917629.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0716 YP_002917630.1 internal ID: KP0717 YP_002917631.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0718 YP_002917632.1 internal ID: KP0719 YP_002917633.1 internal ID: KP0720 YP_002917634.1 internal ID: KP0721 YP_002917635.1 internal ID: KP0722 YP_002917636.1 internal ID: KP0723 YP_002917637.1 internal ID: KP0725 YP_002917638.1 internal ID: KP0726 YP_002917639.1 internal ID: KP0728 YP_002917640.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0729 YP_002917641.1 internal ID: KP0730 YP_002917642.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0731 YP_002917643.1 internal ID: KP0732 YP_002917644.1 internal ID: KP0733 YP_002917645.1 internal ID: KP0734 YP_002917646.1 internal ID: KP0735 YP_002917647.1 internal ID: KP0736 YP_002917648.1 internal ID: KP0737 YP_002917649.1 internal ID: KP0738 YP_002917650.1 internal ID: KP0739 YP_002917651.1 internal ID: KP0740 YP_002917652.1 internal ID: KP0741 YP_002917653.1 internal ID: KP0742 YP_002917654.1 internal ID: KP0743 YP_002917655.1 identified by GeneMark.hmm; internal ID: KP0744 YP_002917656.1 internal ID: KP0745 YP_002917657.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0748 YP_002917658.1 internal ID: KP0749 YP_002917659.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0750 YP_002917660.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0751 YP_002917661.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0752 YP_002917662.1 internal ID: KP0753 YP_002917663.1 internal ID: KP0754 YP_002917664.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism YP_002917665.1 internal ID: KP0756 YP_002917666.1 internal ID: KP0757 YP_002917667.1 internal ID: KP0758 YP_002917668.1 internal ID: KP0759 YP_002917669.1 internal ID: KP0760 YP_002917670.1 internal ID: KP0761 YP_002917671.1 internal ID: KP0762 YP_002917672.1 internal ID: KP0763 YP_002917673.1 internal ID: KP0764 YP_002917674.1 internal ID: KP0765 YP_002917675.1 internal ID: KP0766 YP_002917676.1 catalyzes the transfer of phosphoglycerol to the glucan backbone YP_002917677.1 internal ID: KP0769 YP_002917678.1 acts to load the DnaB helicase onto the initiation site during DNA replication YP_002917679.1 This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N' YP_002917680.1 internal ID: KP0772 YP_002917681.1 internal ID: KP0773 YP_002917682.1 identified by Glimmer2; internal ID: KP0774 YP_002917683.1 catalyzes the formation of protocatechuate from 4-hydroxybenzoate YP_002917684.1 internal ID: KP0776 YP_002917685.1 internal ID: KP0777 YP_002917686.1 regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin YP_002917687.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0779 YP_002917688.1 internal ID: KP0780 YP_002917689.1 internal ID: KP0781 YP_002917690.1 internal ID: KP0782 YP_002917691.1 internal ID: KP0784 YP_002917692.1 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit YP_002917693.1 with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_002917694.1 alanine acetyltransferase that specifically acetylates ribosomal protein S18 YP_002917695.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily YP_002917696.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_002917697.1 internal ID: KP0790 YP_002917698.1 internal ID: KP0791 YP_002917699.1 internal ID: KP0792 YP_002917700.1 internal ID: KP0793 YP_002917701.1 internal ID: KP0794 YP_002917702.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_002917703.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate YP_002917704.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_002917705.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0801 YP_002917706.1 Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins YP_002917707.1 internal ID: KP0803 YP_002917708.1 catalyzes the formation of serine from O-phosphoserine YP_002917709.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_002917710.1 catalyzes the formation of NAD(+) from nicotinamide ribonucleotide YP_002917711.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_002917712.1 catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan YP_002917713.1 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription YP_002917714.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog YP_002917715.1 catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate YP_002917716.1 internal ID: KP0813 YP_002917717.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0814 YP_002917718.1 response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation YP_002917719.1 part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation YP_002917720.1 internal ID: KP0817 YP_002917721.1 internal ID: KP0818 YP_002917722.1 member of the SPOUT superfamily of methyltransferases YP_002917723.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_002917724.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_002917725.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_002917726.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0824 YP_002917727.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0825 YP_002917728.1 internal ID: KP0826 YP_002917729.1 internal ID: KP0827 YP_002917730.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis YP_002917731.1 internal ID: KP0830 YP_002917732.1 internal ID: KP0831 YP_002917733.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0832 YP_002917734.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0833 YP_002917735.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_002917736.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_002917737.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH YP_002917738.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC YP_002917739.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_002917740.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities YP_002917741.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_002917742.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_002917743.1 internal ID: KP0844 YP_002917744.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_002917745.1 catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides YP_002917746.1 identified by GeneMark.hmm; internal ID: KP0847 YP_002917747.1 internal ID: KP0848 YP_002917748.1 internal ID: KP0849 YP_002917749.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_002917750.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_002917751.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_002917752.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0855 YP_002917753.1 Required for full activity of KefC, a potassium-proton antiporter YP_002917754.1 transport system that facilitates potassium-efflux YP_002917755.1 catalyzes the reduction of dihydrofolate to tetrahydrofolate YP_002917756.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP YP_002917757.1 protein associated with Co2+ and Mg2+ efflux YP_002917758.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_002917759.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_002917760.1 Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB YP_002917761.1 determines N-hexane tolerance and is involved in outer membrane permeability YP_002917762.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system YP_002917763.1 internal ID: KP0866 YP_002917764.1 internal ID: KP0867 YP_002917765.1 internal ID: KP0868 YP_002917766.1 internal ID: KP0869 YP_002917767.1 catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs YP_002917768.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA YP_002917769.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C YP_002917770.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_002917771.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism YP_002917772.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate YP_002917773.1 positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose YP_002917774.1 internal ID: KP0877 YP_002917775.1 with TbpA and ThiP is part of the thiamine and TPP transport system YP_002917776.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine YP_002917777.1 part of the thiamine and TPP transport system tbpA-thiPQ YP_002917778.1 activates sgrS under glucose-phosphate stress conditions YP_002917779.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0882 YP_002917780.1 internal ID: KP0883 YP_002917781.1 internal ID: KP0884 YP_002917782.1 internal ID: KP0886 YP_002917783.1 internal ID: KP0888 YP_002917784.1 internal ID: KP0889 YP_002917785.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_002917786.1 internal ID: KP0891 YP_002917787.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_002917788.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_002917789.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_002917790.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_002917791.1 activator for leuABCD operon; member of LysR family of transcriptional activators YP_002917792.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive YP_002917793.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_002917794.1 binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism YP_002917795.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_002917796.1 internal ID: KP0904 YP_002917797.1 membrane bound cell division protein at septum containing leucine zipper motif YP_002917798.1 internal ID: KP0906 YP_002917799.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_002917800.1 internal ID: KP0908 YP_002917801.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_002917802.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_002917803.1 integral membrane protein involved in stabilizing FstZ ring during cell division YP_002917804.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_002917805.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_002917806.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_002917807.1 involved in septum formation YP_002917808.1 ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane YP_002917809.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_002917810.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_002917811.1 secM translational pause allows for the initiation of secA translation YP_002917812.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_002917813.1 internal ID: KP0923 YP_002917814.1 internal ID: KP0924 YP_002917815.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0925 YP_002917816.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_002917817.1 identified by Glimmer2; internal ID: KP0927 YP_002917818.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate YP_002917819.1 internal ID: KP0929 YP_002917820.1 internal ID: KP0930 YP_002917821.1 internal ID: KP0931 YP_002917822.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide YP_002917823.1 internal ID: KP0933 YP_002917824.1 involved in regulation of beta-lactamase; putative signaling protein YP_002917825.1 internal ID: KP0935 YP_002917826.1 internal ID: KP0936 YP_002917827.1 internal ID: KP0938 YP_002917828.1 identified by Glimmer2; internal ID: KP0939 YP_002917829.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex YP_002917830.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_002917831.1 E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains YP_002917832.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_002917833.1 internal ID: KP0945 YP_002917834.1 internal ID: KP0946 YP_002917835.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0947 YP_002917836.1 identified by Glimmer2; internal ID: KP0948 YP_002917837.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_002917838.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0950 YP_002917839.1 S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine YP_002917840.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_002917841.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0953 YP_002917842.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0954 YP_002917843.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP0956 YP_002917844.1 laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification YP_002917845.1 internal ID: KP0958 YP_002917846.1 internal ID: KP0960 YP_002917847.1 catalyzes the interconversion of bicarbonate and carbon dioxide YP_002917848.1 internal ID: KP0962 YP_002917849.1 internal ID: KP0963 YP_002917850.1 internal ID: KP0964 YP_002917851.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP0965 YP_002917852.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_002917853.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_002917854.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_002917855.1 catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP YP_002917856.1 Polymerase that creates the 3' poly(A) tail found in some mRNA's YP_002917857.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu YP_002917858.1 internal ID: KP0973 YP_002917859.1 Regulatory factor involved in maltose metabolism YP_002917860.1 internal ID: KP0975 YP_002917861.1 similar in sequence to the ATP-dependent RNA helicase HrpA YP_002917862.1 internal ID: KP0977 YP_002917863.1 internal ID: KP0978 YP_002917864.1 internal ID: KP0979 YP_002917865.1 internal ID: KP0980 YP_002917866.1 internal ID: KP0982 YP_002917867.1 internal ID: KP0983 YP_002917868.1 internal ID: KP0985 YP_002917869.1 internal ID: KP0986 YP_002917870.1 internal ID: KP0987 YP_002917871.1 internal ID: KP0988 YP_002917872.1 internal ID: KP0989 YP_002917873.1 internal ID: KP0990 YP_002917874.1 internal ID: KP0991 YP_002917875.1 internal ID: KP0994 YP_002917876.1 internal ID: KP0995 YP_002917877.1 internal ID: KP0996 YP_002917878.1 internal ID: KP0997 YP_002917879.1 internal ID: KP0998 YP_002917880.1 identified by GeneMark.hmm; internal ID: KP1000 YP_002917881.1 bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell YP_002917882.1 involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein YP_002917883.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter YP_002917884.1 Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores YP_002917885.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome YP_002917886.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_002917887.1 Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation YP_002917888.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1009 YP_002917889.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1010 YP_002917890.1 solute binding component of the vitamin B12 transport system BtuCDF YP_002917891.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine YP_002917892.1 forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate YP_002917893.1 protease Do; required at high temperature; degrades damaged proteins YP_002917894.1 regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization YP_002917895.1 internal ID: KP1017 YP_002917896.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_002917897.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein YP_002917898.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_002917899.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_002917900.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_002917901.1 Catalyzes the phosphorylation of UMP to UDP YP_002917902.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_002917903.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_002917904.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate YP_002917905.1 catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate YP_002917906.1 catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response YP_002917907.1 part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins YP_002917908.1 internal ID: KP1033 YP_002917909.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_002917910.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_002917911.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_002917912.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_002917913.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_002917914.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_002917915.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_002917916.1 internal ID: KP1043 YP_002917917.1 internal ID: KP1045 YP_002917918.1 internal ID: KP1046 YP_002917919.1 Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination YP_002917920.1 identified by GeneMark.hmm; internal ID: KP1048 YP_002917921.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1049 YP_002917922.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1050 YP_002917923.1 internal ID: KP1051 YP_002917924.1 internal ID: KP1052 YP_002917925.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_002917926.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1054 YP_002917927.1 internal ID: KP1055 YP_002917928.1 internal ID: KP1056 YP_002917929.1 part of the MetNIQ methionine uptake system YP_002917930.1 part of the metNIQ transport system for methionine YP_002917931.1 identified by Glimmer2; internal ID: KP1060 YP_002917932.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate YP_002917933.1 catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid YP_002917934.1 internal ID: KP1066 YP_002917935.1 internal ID: KP1067 YP_002917936.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1068 YP_002917937.1 internal ID: KP1069 YP_002917938.1 catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall YP_002917939.1 catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione YP_002917940.1 internal ID: KP1072 YP_002917941.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_002917942.1 3'-5' exonuclease of DNA polymerase III YP_002917943.1 internal ID: KP1075 YP_002917944.1 internal ID: KP1076 YP_002917945.1 internal ID: KP1077 YP_002917946.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_002917947.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate YP_002917948.1 internal ID: KP1081 YP_002917949.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1082 YP_002917950.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_002917951.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_002917952.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_002917953.1 Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm YP_002917954.1 Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. YP_002917955.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_002917956.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1090 YP_002917957.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1091 YP_002917958.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_002917959.1 internal ID: KP1094 YP_002917960.1 internal ID: KP1095 YP_002917961.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively YP_002917962.1 forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation YP_002917963.1 involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS YP_002917964.1 regulator of gab gene expression YP_002917965.1 internal ID: KP1100 YP_002917966.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_002917967.1 catalyzes the formation of succinate from succinate semialdehyde; NADP dependent YP_002917968.1 catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate YP_002917969.1 in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution YP_002917970.1 internal ID: KP1105 YP_002917971.1 internal ID: KP1106 YP_002917972.1 internal ID: KP1107 YP_002917973.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1108 YP_002917974.1 internal ID: KP1109 YP_002917975.1 internal ID: KP1110 YP_002917976.1 internal ID: KP1111 YP_002917977.1 internal ID: KP1112 YP_002917978.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1114 YP_002917979.1 internal ID: KP1115 YP_002917980.1 internal ID: KP1116 YP_002917981.1 internal ID: KP1117 YP_002917982.1 internal ID: KP1118 YP_002917983.1 internal ID: KP1119 YP_002917984.1 internal ID: KP1121 YP_002917985.1 identified by Glimmer2; internal ID: KP1123 YP_002917986.1 internal ID: KP1124 YP_002917987.1 internal ID: KP1126 YP_002917988.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1127 YP_002917989.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1128 YP_002917990.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1129 YP_002917991.1 identified by GeneMark.hmm; internal ID: KP1130 YP_002917992.1 internal ID: KP1131 YP_002917993.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_002917994.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_002917995.1 identified by Glimmer2; internal ID: KP1134 YP_002917996.1 internal ID: KP1135 YP_002917997.1 internal ID: KP1136 YP_002917998.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1137 YP_002917999.1 internal ID: KP1138 YP_002918000.1 internal ID: KP1139 YP_002918001.1 internal ID: KP1140 YP_002918002.1 internal ID: KP1141 YP_002918003.1 internal ID: KP1142 YP_002918004.1 internal ID: KP1143 YP_002918005.1 identified by Glimmer2; internal ID: KP1144 YP_002918006.1 internal ID: KP1145 YP_002918007.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1146 YP_002918008.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1147 YP_002918009.1 internal ID: KP1148 YP_002918010.1 internal ID: KP1149 YP_002918011.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1150 YP_002918012.1 internal ID: KP1151 YP_002918013.1 internal ID: KP1152 YP_002918014.1 internal ID: KP1153 YP_002918015.1 internal ID: KP1154 YP_002918016.1 internal ID: KP1156 YP_002918017.1 internal ID: KP1157 YP_002918018.1 internal ID: KP1159 YP_002918019.1 internal ID: KP1160 YP_002918020.1 internal ID: KP1161 YP_002918021.1 internal ID: KP1163 YP_002918022.1 internal ID: KP1164 YP_002918023.1 internal ID: KP1165 YP_002918024.1 identified by Glimmer2; internal ID: KP1166 YP_002918025.1 internal ID: KP1167 YP_002918026.1 converts homocysteine and S-adenosyl-methionine to methionine and S-adenosyl-homocysteine or S-methyl-methionine and homocysteine to two methionines YP_002918027.1 internal ID: KP1169 YP_002918028.1 Part of the ABC transporter complex tauABC involved in taurine import YP_002918029.1 internal ID: KP1172 YP_002918030.1 catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers YP_002918031.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1174 YP_002918032.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_002918033.1 this protein has no known enzymatic function YP_002918034.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1177 YP_002918035.1 in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope YP_002918036.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1179 YP_002918037.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1180 YP_002918038.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1181 YP_002918039.1 internal ID: KP1182 YP_002918040.1 internal ID: KP1183 YP_002918041.1 internal ID: KP1184 YP_002918042.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1185 YP_002918043.1 internal ID: KP1186 YP_002918044.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1187 YP_002918045.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_002918046.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1189 YP_002918047.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1190 YP_002918048.1 identified by Glimmer2; internal ID: KP1191 YP_002918049.1 type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_002918050.1 identified by GeneMark and GeneMark.hmm; internal ID: KP1193 YP_002918051.1 internal ID: KP1194 YP_002918052.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1195 YP_002918053.1 Required for efficient pilin antigenic variation YP_002918054.1 internal ID: KP1197 YP_002918055.1 with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity YP_002918056.1 with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity YP_002918057.1 two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB YP_002918058.1 membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB YP_002918059.1 internal ID: KP1203 YP_002918060.1 cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation YP_002918061.1 internal ID: KP1205 YP_002918062.1 internal ID: KP1206 YP_002918063.1 internal ID: KP1207 YP_002918064.1 internal ID: KP1209 YP_002918065.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1210 YP_002918066.1 internal ID: KP1211 YP_002918067.1 internal ID: KP1212 YP_002918068.1 internal ID: KP1213 YP_002918069.1 internal ID: KP1214 YP_002918070.1 internal ID: KP1215 YP_002918071.1 identified by Glimmer2; internal ID: KP1217 YP_002918072.1 internal ID: KP1218 YP_002918073.1 Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP YP_002918074.1 identified by Glimmer2; internal ID: KP1220 YP_002918075.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_002918076.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_002918077.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex YP_002918078.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_002918079.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_002918080.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1227 YP_002918081.1 internal ID: KP1228 YP_002918082.1 internal ID: KP1229 YP_002918083.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1230 YP_002918084.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1231 YP_002918085.1 riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil YP_002918086.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_002918087.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_002918088.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP YP_002918089.1 hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate YP_002918090.1 internal ID: KP1237 YP_002918091.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_002918092.1 internal ID: KP1239 YP_002918093.1 catalyzes the bidirectional exonucleolytic cleavage of DNA YP_002918094.1 Required for the synthesis of the thiazole moiety YP_002918095.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1243 YP_002918096.1 internal ID: KP1244 YP_002918097.1 internal ID: KP1245 YP_002918098.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1246 YP_002918099.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1247 YP_002918100.1 internal ID: KP1248 YP_002918101.1 internal ID: KP1250 YP_002918102.1 internal ID: KP1251 YP_002918103.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1252 YP_002918104.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1253 YP_002918105.1 internal ID: KP1254 YP_002918106.1 internal ID: KP1255 YP_002918107.1 internal ID: KP1256 YP_002918108.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1257 YP_002918109.1 converts protoheme IX and farnesyl diphosphate to heme O YP_002918110.1 internal ID: KP1259 YP_002918111.1 internal ID: KP1260 YP_002918112.1 internal ID: KP1261 YP_002918113.1 internal ID: KP1262 YP_002918114.1 in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein YP_002918115.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1264 YP_002918116.1 identified by Glimmer2; internal ID: KP1266 YP_002918117.1 internal ID: KP1267 YP_002918118.1 identified by Glimmer2; internal ID: KP1268 YP_002918119.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_002918120.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_002918121.1 binds and unfolds substrates as part of the ClpXP protease YP_002918122.1 internal ID: KP1272 YP_002918123.1 histone-like DNA-binding protein YP_002918124.1 internal ID: KP1274 YP_002918125.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1275 YP_002918126.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1276 YP_002918127.1 YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His YP_002918128.1 internal ID: KP1278 YP_002918129.1 internal ID: KP1279 YP_002918130.1 internal ID: KP1280 YP_002918131.1 internal ID: KP1281 YP_002918132.1 internal ID: KP1282 YP_002918133.1 internal ID: KP1283 YP_002918134.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia. YP_002918135.1 internal ID: KP1286 YP_002918136.1 internal ID: KP1287 YP_002918137.1 internal ID: KP1288 YP_002918138.1 internal ID: KP1289 YP_002918139.1 internal ID: KP1290 YP_002918140.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1292 YP_002918141.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1293 YP_002918142.1 internal ID: KP1294 YP_002918143.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1295 YP_002918144.1 membrane protein conferring nickel and cobalt resistance YP_002918145.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1298 YP_002918146.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1299 YP_002918147.1 internal ID: KP1300 YP_002918148.1 identified by Glimmer2; internal ID: KP1301 YP_002918149.1 internal ID: KP1302 YP_002918150.1 internal ID: KP1303 YP_002918151.1 internal ID: KP1304 YP_002918152.1 internal ID: KP1305 YP_002918153.1 internal ID: KP1306 YP_002918154.1 internal ID: KP1307 YP_002918155.1 porin involved in the transport of maltose and maltodextrins YP_002918156.1 transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer YP_002918157.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_002918158.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif YP_002918159.1 internal ID: KP1312 YP_002918160.1 internal ID: KP1313 YP_002918161.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1314 YP_002918162.1 internal ID: KP1316 YP_002918163.1 with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins YP_002918164.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1318 YP_002918165.1 internal ID: KP1319 YP_002918166.1 internal ID: KP1320 YP_002918167.1 regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine YP_002918168.1 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS YP_002918169.1 internal ID: KP1323 YP_002918170.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1324 YP_002918171.1 PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks YP_002918172.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1326 YP_002918173.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_002918174.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA YP_002918175.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1329 YP_002918176.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_002918177.1 molecular chaperone YP_002918178.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_002918179.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_002918180.1 internal ID: KP1336 YP_002918181.1 YbaL; member of the CPA-2 family of antiporters; uncharacterized protein YP_002918182.1 internal ID: KP1338 YP_002918183.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides YP_002918184.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1341 YP_002918185.1 internal ID: KP1342 YP_002918186.1 internal ID: KP1343 YP_002918187.1 internal ID: KP1344 YP_002918188.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1345 YP_002918189.1 internal ID: KP1346 YP_002918190.1 internal ID: KP1347 YP_002918191.1 internal ID: KP1348 YP_002918192.1 internal ID: KP1349 YP_002918193.1 internal ID: KP1350 YP_002918194.1 internal ID: KP1352 YP_002918195.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1353 YP_002918196.1 internal ID: KP1354 YP_002918197.1 internal ID: KP1355 YP_002918198.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA YP_002918199.1 activator of the allDC-ylbA operon involved in allantoin utilization YP_002918200.1 catalyzes the formation of glyoxylate from (S)-ureidoglycolate YP_002918201.1 regulates operons involved in the utilization of allantoin YP_002918202.1 catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate YP_002918203.1 internal ID: KP1362 YP_002918204.1 internal ID: KP1363 YP_002918205.1 internal ID: KP1364 YP_002918206.1 internal ID: KP1365 YP_002918207.1 Plays a crucial role on both purine and pyrimidine metabolism YP_002918208.1 internal ID: KP1368 YP_002918209.1 internal ID: KP1369 YP_002918210.1 internal ID: KP1371 YP_002918211.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_002918212.1 internal ID: KP1373 YP_002918213.1 multicopy suppressor of dominant negative ftsH mutations YP_002918214.1 internal ID: KP1376 YP_002918215.1 internal ID: KP1377 YP_002918216.1 internal ID: KP1378 YP_002918217.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_002918218.1 internal ID: KP1380 YP_002918219.1 identified by GeneMark.hmm; internal ID: KP1381 YP_002918220.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine YP_002918221.1 internal ID: KP1383 YP_002918222.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_002918223.1 internal ID: KP1385 YP_002918224.1 internal ID: KP1386 YP_002918225.1 internal ID: KP1387 YP_002918226.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1389 YP_002918227.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_002918228.1 identified by GeneMark.hmm; internal ID: KP1392 YP_002918229.1 identified by Glimmer2; internal ID: KP1393 YP_002918230.1 identified by GeneMark.hmm; internal ID: KP1394 YP_002918231.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1395 YP_002918232.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1396 YP_002918233.1 identified by Glimmer2; internal ID: KP1397 YP_002918234.1 internal ID: KP1398 YP_002918235.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1399 YP_002918236.1 internal ID: KP1400 YP_002918237.1 internal ID: KP1401 YP_002918238.1 internal ID: KP1402 YP_002918239.1 internal ID: KP1403 YP_002918240.1 internal ID: KP1404 YP_002918241.1 internal ID: KP1405 YP_002918242.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA YP_002918243.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1407 YP_002918244.1 regulates the cadBA operon YP_002918245.1 antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein YP_002918246.1 internal ID: KP1410 YP_002918247.1 internal ID: KP1412 YP_002918248.1 class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and low pH; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_002918249.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1415 YP_002918250.1 identified by Glimmer2; internal ID: KP1416 YP_002918251.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1417 YP_002918252.1 internal ID: KP1418 YP_002918253.1 internal ID: KP1419 YP_002918254.1 internal ID: KP1420 YP_002918255.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1421 YP_002918256.1 internal ID: KP1422 YP_002918257.1 internal ID: KP1423 YP_002918258.1 internal ID: KP1424 YP_002918259.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1426 YP_002918260.1 internal ID: KP1428 YP_002918261.1 internal ID: KP1429 YP_002918262.1 internal ID: KP1431 YP_002918263.1 internal ID: KP1432 YP_002918264.1 identified by Glimmer2; internal ID: KP1433 YP_002918265.1 phosphorylates aminoimidazole ribotide (AIR) which forms 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate (HMP-P); synthesis of HMP-P from AIR is complex and requires the product of thiC gene at least YP_002918266.1 identified by Glimmer2; internal ID: KP1435 YP_002918267.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1436 YP_002918268.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1437 YP_002918269.1 internal ID: KP1438 YP_002918270.1 internal ID: KP1439 YP_002918271.1 internal ID: KP1440 YP_002918272.1 internal ID: KP1441 YP_002918273.1 identified by Glimmer2; internal ID: KP1442 YP_002918274.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1443 YP_002918275.1 internal ID: KP1444 YP_002918276.1 identified by Glimmer2; internal ID: KP1445 YP_002918277.1 identified by Glimmer2; internal ID: KP1447 YP_002918278.1 internal ID: KP1448 YP_002918279.1 internal ID: KP1449 YP_002918280.1 internal ID: KP1450 YP_002918281.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1451 YP_002918282.1 internal ID: KP1452 YP_002918283.1 internal ID: KP1453 YP_002918284.1 internal ID: KP1454 YP_002918285.1 internal ID: KP1455 YP_002918286.1 internal ID: KP1456 YP_002918287.1 internal ID: KP1457 YP_002918288.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1458 YP_002918289.1 internal ID: KP1459 YP_002918290.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1461 YP_002918291.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1462 YP_002918292.1 internal ID: KP1463 YP_002918293.1 internal ID: KP1465 YP_002918294.1 internal ID: KP1466 YP_002918295.1 internal ID: KP1467 YP_002918296.1 internal ID: KP1469 YP_002918297.1 internal ID: KP1471 YP_002918298.1 internal ID: KP1472 YP_002918299.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1473 YP_002918300.1 internal ID: KP1474 YP_002918301.1 internal ID: KP1475 YP_002918302.1 internal ID: KP1476 YP_002918303.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1477 YP_002918304.1 internal ID: KP1478 YP_002918305.1 internal ID: KP1479 YP_002918306.1 internal ID: KP1480 YP_002918307.1 internal ID: KP1481 YP_002918308.1 internal ID: KP1482 YP_002918309.1 internal ID: KP1483 YP_002918310.1 internal ID: KP1484 YP_002918311.1 internal ID: KP1485 YP_002918312.1 catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive YP_002918313.1 internal ID: KP1488 YP_002918314.1 internal ID: KP1490 YP_002918315.1 internal ID: KP1491 YP_002918316.1 internal ID: KP1492 YP_002918317.1 internal ID: KP1493 YP_002918318.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1494 YP_002918319.1 internal ID: KP1495 YP_002918320.1 internal ID: KP1497 YP_002918321.1 internal ID: KP1498 YP_002918322.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1499 YP_002918323.1 ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity YP_002918324.1 internal ID: KP1501 YP_002918325.1 internal ID: KP1502 YP_002918326.1 internal ID: KP1503 YP_002918327.1 internal ID: KP1505 YP_002918328.1 internal ID: KP1507 YP_002918329.1 internal ID: KP1508 YP_002918330.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1509 YP_002918331.1 internal ID: KP1510 YP_002918332.1 internal ID: KP1511 YP_002918333.1 internal ID: KP1512 YP_002918334.1 internal ID: KP1513 YP_002918335.1 internal ID: KP1514 YP_002918336.1 internal ID: KP1515 YP_002918337.1 internal ID: KP1516 YP_002918338.1 internal ID: KP1518 YP_002918339.1 internal ID: KP1519 YP_002918340.1 internal ID: KP1520 YP_002918341.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1521 YP_002918342.1 internal ID: KP1522 YP_002918343.1 internal ID: KP1523 YP_002918344.1 internal ID: KP1524 YP_002918345.1 internal ID: KP1525 YP_002918346.1 internal ID: KP1526 YP_002918347.1 internal ID: KP1527 YP_002918348.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine YP_002918349.1 catalyzes the formation of betaine from betaine aldehyde YP_002918350.1 HTH-type; bet1; Repressor involved in choline regulation of the bet genes YP_002918351.1 proton-motive-force-driven choline transporter YP_002918352.1 inactivates vertebrate C-type lysozyme YP_002918353.1 internal ID: KP1533 YP_002918354.1 internal ID: KP1534 YP_002918355.1 internal ID: KP1535 YP_002918356.1 internal ID: KP1536 YP_002918357.1 internal ID: KP1537 YP_002918358.1 internal ID: KP1538 YP_002918359.1 internal ID: KP1539 YP_002918360.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1540 YP_002918361.1 internal ID: KP1541 YP_002918362.1 internal ID: KP1542 YP_002918363.1 internal ID: KP1543 YP_002918364.1 internal ID: KP1544 YP_002918365.1 internal ID: KP1545 YP_002918366.1 internal ID: KP1546 YP_002918367.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space YP_002918368.1 internal ID: KP1548 YP_002918369.1 internal ID: KP1549 YP_002918370.1 with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin YP_002918371.1 with FepBDE is involved in the transport of ferric enterobactin YP_002918372.1 with FepBCD is involved in the transport of ferric enterobactin YP_002918373.1 with FepBCG is involved in the transport of ferric enterobactin YP_002918374.1 identified by Glimmer2; internal ID: KP1554 YP_002918375.1 protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters YP_002918376.1 with FepCDG is involved in the transport of ferric enterobactin YP_002918377.1 internal ID: KP1557 YP_002918378.1 bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate YP_002918379.1 internal ID: KP1559 YP_002918380.1 catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin YP_002918381.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1562 YP_002918382.1 internal ID: KP1563 YP_002918383.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1564 YP_002918384.1 internal ID: KP1565 YP_002918385.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1566 YP_002918386.1 internal ID: KP1567 YP_002918387.1 member of the iron-containing alcohol dehydrogenase family; unknown function YP_002918388.1 internal ID: KP1570 YP_002918389.1 internal ID: KP1571 YP_002918390.1 internal ID: KP1573 YP_002918391.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1574 YP_002918392.1 phosphorylates methylthioribose to form methylthioribose-1-phosphate; involved in methionine salvage pathway YP_002918393.1 internal ID: KP1577 YP_002918394.1 internal ID: KP1578 YP_002918395.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1579 YP_002918396.1 internal ID: KP1580 YP_002918397.1 internal ID: KP1581 YP_002918398.1 internal ID: KP1582 YP_002918399.1 internal ID: KP1583 YP_002918400.1 internal ID: KP1584 YP_002918401.1 catalyzes the formation of diketo methylthiopentyl phosphate from methylribulose phosphate in the methionine salvage pathway YP_002918402.1 internal ID: KP1586 YP_002918403.1 internal ID: KP1587 YP_002918404.1 internal ID: KP1588 YP_002918405.1 internal ID: KP1589 YP_002918406.1 internal ID: KP1590 YP_002918407.1 internal ID: KP1591 YP_002918408.1 internal ID: KP1592 YP_002918409.1 internal ID: KP1593 YP_002918410.1 internal ID: KP1594 YP_002918411.1 internal ID: KP1595 YP_002918412.1 catalyzes the transfer of an amino moiety YP_002918413.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1597 YP_002918414.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1598 YP_002918415.1 internal ID: KP1599 YP_002918416.1 internal ID: KP1600 YP_002918417.1 identified by Glimmer2; internal ID: KP1601 YP_002918418.1 with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate YP_002918419.1 internal ID: KP1603 YP_002918420.1 internal ID: KP1605 YP_002918421.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation YP_002918422.1 internal ID: KP1607 YP_002918423.1 responsible for the transport of C4-dicarboxylates during anaerobic growth YP_002918424.1 catalyzes the transfer of palmitate to lipid A YP_002918425.1 member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator YP_002918426.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_002918427.1 internal ID: KP1613 YP_002918428.1 TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_002918429.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_002918430.1 internal ID: KP1616 YP_002918431.1 internal ID: KP1617 YP_002918432.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1618 YP_002918433.1 penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors YP_002918434.1 internal ID: KP1620 YP_002918435.1 internal ID: KP1621 YP_002918436.1 internal ID: KP1622 YP_002918437.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_002918438.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1624 YP_002918439.1 internal ID: KP1625 YP_002918440.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria YP_002918441.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA YP_002918442.1 internal ID: KP1628 YP_002918443.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_002918444.1 internal ID: KP1631 YP_002918445.1 internal ID: KP1632 YP_002918446.1 internal ID: KP1633 YP_002918447.1 internal ID: KP1635 YP_002918448.1 internal ID: KP1636 YP_002918449.1 internal ID: KP1637 YP_002918450.1 internal ID: KP1638 YP_002918451.1 Transfers the fatty acyl group on membrane lipoproteins YP_002918452.1 internal ID: KP1640 YP_002918453.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1641 YP_002918454.1 internal ID: KP1642 YP_002918455.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_002918456.1 catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q YP_002918457.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP YP_002918458.1 internal ID: KP1646 YP_002918459.1 internal ID: KP1647 YP_002918460.1 catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate YP_002918461.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate YP_002918462.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002918463.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002918464.1 internal ID: KP1654 YP_002918465.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1655 YP_002918466.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1656 YP_002918467.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1657 YP_002918468.1 internal ID: KP1658 YP_002918469.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer YP_002918470.1 internal ID: KP1660 YP_002918471.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1661 YP_002918472.1 internal ID: KP1662 YP_002918473.1 negative modulator of the initiation of chromosome replication YP_002918474.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_002918475.1 internal ID: KP1665 YP_002918476.1 internal ID: KP1666 YP_002918477.1 sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein YP_002918478.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex YP_002918479.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_002918480.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_002918481.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1671 YP_002918482.1 UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent YP_002918483.1 internal ID: KP1673 YP_002918484.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1674 YP_002918485.1 internal ID: KP1675 YP_002918486.1 internal ID: KP1676 YP_002918487.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1677 YP_002918488.1 internal ID: KP1678 YP_002918489.1 internal ID: KP1679 YP_002918490.1 catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline YP_002918491.1 5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity YP_002918492.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH YP_002918493.1 internal ID: KP1683 YP_002918494.1 internal ID: KP1684 YP_002918495.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_002918496.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_002918497.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_002918498.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA YP_002918499.1 catalyzes the interconversion of succinyl-CoA and succinate YP_002918500.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle YP_002918501.1 identified by Glimmer2; internal ID: KP1692 YP_002918502.1 internal ID: KP1693 YP_002918503.1 internal ID: KP1694 YP_002918504.1 internal ID: KP1695 YP_002918505.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1696 YP_002918506.1 catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components YP_002918507.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins YP_002918508.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins YP_002918509.1 inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins YP_002918510.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_002918511.1 internal ID: KP1704 YP_002918512.1 periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity YP_002918513.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_002918514.1 internal ID: KP1707 YP_002918515.1 involved in zinc efflux across the cytoplasmic membrane YP_002918516.1 internal ID: KP1709 YP_002918517.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_002918518.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate YP_002918519.1 catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose YP_002918520.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism YP_002918521.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P YP_002918522.1 internal ID: KP1717 YP_002918523.1 contains 2 ATP-binding cassettes; involved in the transport of molybdenum YP_002918524.1 represses the modABCD operon and activates the moaABCD and napFDAGHBC operons YP_002918525.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1720 YP_002918526.1 with ModCB is involved in the high-affinity transport of molybdate YP_002918527.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE YP_002918528.1 Part of the ABC transporter complex modABC involved in molybdenum import YP_002918529.1 YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily YP_002918530.1 catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate YP_002918531.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1726 YP_002918532.1 identified by GeneMark.hmm; internal ID: KP1727 YP_002918533.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1728 YP_002918534.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1729 YP_002918535.1 internal ID: KP1730 YP_002918536.1 internal ID: KP1731 YP_002918537.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1732 YP_002918538.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1733 YP_002918539.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1734 YP_002918540.1 internal ID: KP1735 YP_002918541.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1737 YP_002918542.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1738 YP_002918543.1 internal ID: KP1739 YP_002918544.1 internal ID: KP1740 YP_002918545.1 outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase family YP_002918546.1 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway YP_002918547.1 catalyzes the formation of glutamate and formamide from N-formimidoyl-L-glutamate YP_002918548.1 internal ID: KP1744 YP_002918549.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_002918550.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_002918551.1 internal ID: KP1747 YP_002918552.1 YbhB; similar to rat and human kinase inhibitory proteins YP_002918553.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate YP_002918554.1 internal ID: KP1750 YP_002918555.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine YP_002918556.1 putative methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth YP_002918557.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_002918558.1 internal ID: KP1754 YP_002918559.1 identified by Glimmer2; internal ID: KP1755 YP_002918560.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_002918561.1 internal ID: KP1759 YP_002918562.1 response regulator in two-component regulatory system with BasS YP_002918563.1 with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division YP_002918564.1 internal ID: KP1762 YP_002918565.1 identified by Glimmer2; internal ID: KP1763 YP_002918566.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_002918567.1 internal ID: KP1765 YP_002918568.1 internal ID: KP1766 YP_002918569.1 internal ID: KP1767 YP_002918570.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin YP_002918571.1 internal ID: KP1769 YP_002918572.1 internal ID: KP1770 YP_002918573.1 internal ID: KP1771 YP_002918574.1 internal ID: KP1772 YP_002918575.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1773 YP_002918576.1 internal ID: KP1774 YP_002918577.1 internal ID: KP1775 YP_002918578.1 internal ID: KP1776 YP_002918579.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1777 YP_002918580.1 internal ID: KP1778 YP_002918581.1 internal ID: KP1779 YP_002918582.1 identified by Glimmer2; internal ID: KP1780 YP_002918583.1 internal ID: KP1781 YP_002918584.1 internal ID: KP1782 YP_002918585.1 internal ID: KP1783 YP_002918586.1 internal ID: KP1784 YP_002918587.1 this helicase is not essential cell growth YP_002918588.1 helicase involved in DNA repair and perhaps also replication YP_002918589.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1787 YP_002918590.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1788 YP_002918591.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1789 YP_002918592.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1790 YP_002918593.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1791 YP_002918594.1 identified by Glimmer2; internal ID: KP1792 YP_002918595.1 internal ID: KP1793 YP_002918596.1 internal ID: KP1794 YP_002918597.1 similar to ATP-binding component of ABC transporters YP_002918598.1 similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine YP_002918599.1 similar to periplasmic-binding component of ABC transporters YP_002918600.1 binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage YP_002918601.1 internal ID: KP1800 YP_002918602.1 OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains YP_002918603.1 internal ID: KP1802 YP_002918604.1 identified by Glimmer2; internal ID: KP1803 YP_002918605.1 Transcriptional regulator that represses the manganese transporter MntH when manganese is present YP_002918606.1 internal ID: KP1805 YP_002918607.1 internal ID: KP1806 YP_002918608.1 internal ID: KP1807 YP_002918609.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1808 YP_002918610.1 internal ID: KP1809 YP_002918611.1 internal ID: KP1810 YP_002918612.1 internal ID: KP1811 YP_002918613.1 internal ID: KP1812 YP_002918614.1 internal ID: KP1813 YP_002918615.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1814 YP_002918616.1 internal ID: KP1815 YP_002918617.1 internal ID: KP1816 YP_002918618.1 internal ID: KP1817 YP_002918619.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase YP_002918620.1 is involved in the formation of active molybdenum cofactor and the chelation of molybdenum YP_002918621.1 internal ID: KP1820 YP_002918622.1 with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains YP_002918623.1 internal ID: KP1822 YP_002918624.1 internal ID: KP1823 YP_002918625.1 internal ID: KP1824 YP_002918626.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit YP_002918627.1 internal ID: KP1826 YP_002918628.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing YP_002918629.1 internal ID: KP1828 YP_002918630.1 internal ID: KP1829 YP_002918631.1 identified by Glimmer2; internal ID: KP1830 YP_002918632.1 identified by Glimmer2; internal ID: KP1831 YP_002918633.1 penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains YP_002918634.1 internal ID: KP1833 YP_002918635.1 internal ID: KP1835 YP_002918636.1 internal ID: KP1836 YP_002918637.1 internal ID: KP1837 YP_002918638.1 internal ID: KP1838 YP_002918639.1 internal ID: KP1839 YP_002918640.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1841 YP_002918641.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1842 YP_002918642.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase YP_002918643.1 YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function YP_002918644.1 NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds YP_002918645.1 internal ID: KP1846 YP_002918646.1 internal ID: KP1847 YP_002918647.1 internal ID: KP1848 YP_002918648.1 part of the PotFGHI ATP-dependent putrescine transporter YP_002918649.1 internal ID: KP1850 YP_002918650.1 internal ID: KP1852 YP_002918651.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1853 YP_002918652.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA YP_002918653.1 internal ID: KP1855 YP_002918654.1 internal ID: KP1856 YP_002918655.1 internal ID: KP1858 YP_002918656.1 with ArtPQJI acts to transport arginine across the inner membrane YP_002918657.1 with ArtPMJI transports arginine across the inner membrane YP_002918658.1 internal ID: KP1861 YP_002918659.1 With ArtMQJI transports arginine across the inner membrane YP_002918660.1 induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS YP_002918661.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1864 YP_002918662.1 internal ID: KP1865 YP_002918663.1 internal ID: KP1866 YP_002918664.1 internal ID: KP1867 YP_002918665.1 low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine YP_002918666.1 catalyzes the formation of acetate from pyruvate YP_002918667.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1871 YP_002918668.1 internal ID: KP1872 YP_002918669.1 catalyzes the reduction of hydroxylamine to ammonia and water YP_002918670.1 internal ID: KP1874 YP_002918671.1 porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure YP_002918672.1 identified by Glimmer2; internal ID: KP1876 YP_002918673.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1877 YP_002918674.1 confers macrolide resistance via active drug efflux YP_002918675.1 with MacA is involved in the export of macrolide YP_002918676.1 internal ID: KP1881 YP_002918677.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_002918678.1 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates YP_002918679.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_002918680.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_002918681.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_002918682.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_002918683.1 catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding YP_002918684.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system YP_002918685.1 internal ID: KP1891 YP_002918686.1 participates with LolB in the incorporation of lipoprotein into the outer membrane YP_002918687.1 internal ID: KP1893 YP_002918688.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002918689.1 internal ID: KP1895 YP_002918690.1 internal ID: KP1897 YP_002918691.1 internal ID: KP1898 YP_002918692.1 internal ID: KP1899 YP_002918693.1 activates pyruvate formate-lyase 1 under anaerobic conditions YP_002918694.1 internal ID: KP1902 YP_002918695.1 internal ID: KP1903 YP_002918696.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1904 YP_002918697.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1905 YP_002918698.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_002918699.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_002918700.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_002918701.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_002918702.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_002918703.1 internal ID: KP1913 YP_002918704.1 involved in the transport of lipid A across the inner membrane YP_002918705.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_002918706.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1916 YP_002918707.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1917 YP_002918708.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_002918709.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1919 YP_002918710.1 internal ID: KP1920 YP_002918711.1 involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA YP_002918712.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division YP_002918713.1 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division YP_002918714.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects YP_002918715.1 internal ID: KP1925 YP_002918716.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1926 YP_002918717.1 internal ID: KP1927 YP_002918718.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_002918719.1 internal ID: KP1929 YP_002918720.1 identified by Glimmer2; internal ID: KP1930 YP_002918721.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002918722.1 internal ID: KP1932 YP_002918723.1 catalyzes the formation of pyruvate from 2,3-diaminopropionate YP_002918724.1 internal ID: KP1934 YP_002918725.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_002918726.1 internal ID: KP1936 YP_002918727.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate YP_002918728.1 identified by GeneMark.hmm; internal ID: KP1938 YP_002918729.1 internal ID: KP1939 YP_002918730.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease YP_002918731.1 part of the ABC type transport system for alkanesulfonate SsuABC; SsuB the ATP-binding subunit and SsuC the permease YP_002918732.1 catalyzes the release of sulfite from alkanesulfonates YP_002918733.1 internal ID: KP1943 YP_002918734.1 internal ID: KP1944 YP_002918735.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_002918736.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1947 YP_002918737.1 internal ID: KP1948 YP_002918738.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA YP_002918739.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth YP_002918740.1 internal ID: KP1951 YP_002918741.1 internal ID: KP1952 YP_002918742.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1953 YP_002918743.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP YP_002918744.1 internal ID: KP1956 YP_002918745.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1957 YP_002918746.1 OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d YP_002918747.1 identified by Glimmer2; internal ID: KP1959 YP_002918748.1 internal ID: KP1960 YP_002918749.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP1961 YP_002918750.1 internal ID: KP1962 YP_002918751.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP1963 YP_002918752.1 catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand YP_002918753.1 internal ID: KP1965 YP_002918754.1 internal ID: KP1966 YP_002918755.1 internal ID: KP1967 YP_002918756.1 internal ID: KP1968 YP_002918757.1 internal ID: KP1969 YP_002918758.1 internal ID: KP1970 YP_002918759.1 catalyzes the hydrolysis of acylphosphate YP_002918760.1 transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs YP_002918761.1 internal ID: KP1973 YP_002918762.1 internal ID: KP1974 YP_002918763.1 identified by Glimmer2; internal ID: KP1975 YP_002918764.1 internal ID: KP1976 YP_002918765.1 internal ID: KP1977 YP_002918766.1 internal ID: KP1978 YP_002918767.1 identified by Glimmer2; internal ID: KP1979 YP_002918768.1 internal ID: KP1980 YP_002918769.1 internal ID: KP1981 YP_002918770.1 internal ID: KP1982 YP_002918771.1 internal ID: KP1983 YP_002918772.1 internal ID: KP1984 YP_002918773.1 identified by Glimmer2; internal ID: KP1985 YP_002918774.1 internal ID: KP1986 YP_002918775.1 FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog YP_002918776.1 internal ID: KP1988 YP_002918777.1 involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein YP_002918778.1 FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS YP_002918779.1 FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site YP_002918780.1 internal ID: KP1993 YP_002918781.1 internal ID: KP1994 YP_002918782.1 internal ID: KP1995 YP_002918783.1 internal ID: KP1996 YP_002918784.1 member of the betaine, carnitine, choline transporter (BCCT) family; unknown function YP_002918785.1 internal ID: KP1998 YP_002918786.1 internal ID: KP2000 YP_002918787.1 internal ID: KP2001 YP_002918788.1 catalyzes the formation of gamma-glutamyl-gamma-aminobutyrate from Gamma-glutamyl-gamma-aminobutyraldehyde; involved in putrescine degradation YP_002918789.1 identified by Glimmer2; internal ID: KP2003 YP_002918790.1 regulates genes involved in putrescine degradation YP_002918791.1 catalyzes the degradation of gamma-glutamyl-gamma-aminobutyrate into glutamate and gamma-aminobutyrate YP_002918792.1 internal ID: KP2006 YP_002918793.1 internal ID: KP2007 YP_002918794.1 identified by Glimmer2; internal ID: KP2008 YP_002918795.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2009 YP_002918796.1 internal ID: KP2010 YP_002918797.1 internal ID: KP2012 YP_002918798.1 internal ID: KP2013 YP_002918799.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2014 YP_002918800.1 stationary phase protein that binds TrpR repressor YP_002918801.1 identified by Glimmer2; internal ID: KP2016 YP_002918802.1 identified by Glimmer2; internal ID: KP2017 YP_002918803.1 identified by GeneMark.hmm; internal ID: KP2018 YP_002918804.1 internal ID: KP2019 YP_002918805.1 internal ID: KP2020 YP_002918806.1 internal ID: KP2021 YP_002918807.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2022 YP_002918808.1 internal ID: KP2023 YP_002918809.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2024 YP_002918810.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2025 YP_002918811.1 internal ID: KP2027 YP_002918812.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2028 YP_002918813.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2029 YP_002918814.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein YP_002918815.1 internal ID: KP2031 YP_002918816.1 internal ID: KP2033 YP_002918817.1 internal ID: KP2034 YP_002918818.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2035 YP_002918819.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2036 YP_002918820.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2037 YP_002918821.1 internal ID: KP2038 YP_002918822.1 internal ID: KP2039 YP_002918823.1 internal ID: KP2040 YP_002918824.1 internal ID: KP2041 YP_002918825.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2042 YP_002918826.1 internal ID: KP2043 YP_002918827.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2044 YP_002918828.1 internal ID: KP2045 YP_002918829.1 internal ID: KP2046 YP_002918830.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2047 YP_002918831.1 internal ID: KP2048 YP_002918832.1 required for the transfer of succinyl residues to the glucan backbone YP_002918833.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan YP_002918834.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space YP_002918835.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2052 YP_002918836.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2053 YP_002918837.1 Confers resistance to fosfomycin and deoxycholate YP_002918838.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA YP_002918839.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2057 YP_002918840.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2058 YP_002918841.1 catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids YP_002918842.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing YP_002918843.1 internal ID: KP2061 YP_002918844.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_002918845.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2064 YP_002918846.1 Confers resistance to norfloxacin and enoxacin YP_002918847.1 internal ID: KP2067 YP_002918848.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2068 YP_002918849.1 internal ID: KP2069 YP_002918850.1 internal ID: KP2070 YP_002918851.1 internal ID: KP2072 YP_002918852.1 internal ID: KP2073 YP_002918853.1 bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase YP_002918854.1 catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA YP_002918855.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_002918856.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2077 YP_002918857.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_002918858.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_002918859.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_002918860.1 internal ID: KP2081 YP_002918861.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_002918862.1 carries the fatty acid chain in fatty acid biosynthesis YP_002918863.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_002918864.1 internal ID: KP2085 YP_002918865.1 internal ID: KP2086 YP_002918866.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_002918867.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA YP_002918868.1 internal ID: KP2089 YP_002918869.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002918870.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2092 YP_002918871.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2093 YP_002918872.1 internal ID: KP2094 YP_002918873.1 catalyzes the phosphorylation of thiamine to thiamine phosphate YP_002918874.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides YP_002918875.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2097 YP_002918876.1 internal ID: KP2098 YP_002918877.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2100 YP_002918878.1 internal ID: KP2101 YP_002918879.1 internal ID: KP2102 YP_002918880.1 identified by Glimmer2; internal ID: KP2103 YP_002918881.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2104 YP_002918882.1 internal ID: KP2105 YP_002918883.1 internal ID: KP2106 YP_002918884.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane YP_002918885.1 internal ID: KP2108 YP_002918886.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane YP_002918887.1 catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine YP_002918888.1 Modulates the activities of several enzymes which are inactive in their acetylated form YP_002918889.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2112 YP_002918890.1 internal ID: KP2113 YP_002918891.1 internal ID: KP2114 YP_002918892.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_002918893.1 internal ID: KP2116 YP_002918894.1 transports degraded pectin products into the bacterial cell YP_002918895.1 internal ID: KP2118 YP_002918896.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity YP_002918897.1 internal ID: KP2122 YP_002918898.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_002918899.1 internal ID: KP2124 YP_002918900.1 internal ID: KP2125 YP_002918901.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate YP_002918902.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component YP_002918903.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component YP_002918904.1 functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase YP_002918905.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_002918906.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2132 YP_002918907.1 internal ID: KP2133 YP_002918908.1 internal ID: KP2134 YP_002918909.1 internal ID: KP2135 YP_002918910.1 internal ID: KP2136 YP_002918911.1 response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress YP_002918912.1 internal ID: KP2138 YP_002918913.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2139 YP_002918914.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_002918915.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis YP_002918916.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_002918917.1 internal ID: KP2144 YP_002918918.1 internal ID: KP2145 YP_002918919.1 Converts isocitrate to alpha ketoglutarate YP_002918920.1 internal ID: KP2147 YP_002918921.1 internal ID: KP2148 YP_002918922.1 identified by GeneMark and GeneMark.hmm; internal ID: KP2149 YP_002918923.1 identified by GeneMark.hmm; internal ID: KP2150 YP_002918924.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2152 YP_002918925.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2154 YP_002918926.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2156 YP_002918927.1 identified by GeneMark and GeneMark.hmm; internal ID: KP2157 YP_002918928.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2158 YP_002918929.1 internal ID: KP2159 YP_002918930.1 internal ID: KP2160 YP_002918931.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2161 YP_002918932.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2163 YP_002918933.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2164 YP_002918934.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2165 YP_002918935.1 internal ID: KP2166 YP_002918936.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2167 YP_002918937.1 internal ID: KP2168 YP_002918938.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2169 YP_002918939.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2170 YP_002918940.1 internal ID: KP2171 YP_002918941.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2172 YP_002918942.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2173 YP_002918943.1 internal ID: KP2175 YP_002918944.1 identified by GeneMark.hmm; internal ID: KP2176 YP_002918945.1 internal ID: KP2177 YP_002918946.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2178 YP_002918947.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2180 YP_002918948.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2181 YP_002918949.1 internal ID: KP2183 YP_002918950.1 identified by Glimmer2; internal ID: KP2184 YP_002918951.1 internal ID: KP2185 YP_002918952.1 internal ID: KP2186 YP_002918953.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2187 YP_002918954.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2188 YP_002918955.1 identified by Glimmer2; internal ID: KP2189 YP_002918956.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2190 YP_002918957.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2191 YP_002918958.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2192 YP_002918959.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2193 YP_002918960.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2194 YP_002918961.1 internal ID: KP2195 YP_002918962.1 identified by Glimmer2; internal ID: KP2196 YP_002918963.1 internal ID: KP2197 YP_002918964.1 internal ID: KP2198 YP_002918965.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2199 YP_002918966.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2200 YP_002918967.1 identified by Glimmer2; internal ID: KP2201 YP_002918968.1 internal ID: KP2202 YP_002918969.1 internal ID: KP2204 YP_002918970.1 binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization YP_002918971.1 binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization YP_002918972.1 internal ID: KP2207 YP_002918973.1 internal ID: KP2208 YP_002918974.1 internal ID: KP2209 YP_002918975.1 internal ID: KP2210 YP_002918976.1 identified by Glimmer2; internal ID: KP2211 YP_002918977.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2212 YP_002918978.1 internal ID: KP2213 YP_002918979.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2214 YP_002918980.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2215 YP_002918981.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2216 YP_002918982.1 internal ID: KP2218 YP_002918983.1 internal ID: KP2219 YP_002918984.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2220 YP_002918985.1 internal ID: KP2222 YP_002918986.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress YP_002918987.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2224 YP_002918988.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2225 YP_002918989.1 internal ID: KP2226 YP_002918990.1 internal ID: KP2227 YP_002918991.1 internal ID: KP2228 YP_002918992.1 converts asparagine to aspartate and ammonia YP_002918993.1 SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane YP_002918994.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2231 YP_002918995.1 internal ID: KP2232 YP_002918996.1 catalyzes the formation of selenophosphate from selenide and ATP YP_002918997.1 decatenates replicating daughter chromosomes YP_002918998.1 internal ID: KP2237 YP_002918999.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer YP_002919000.1 internal ID: KP2239 YP_002919001.1 internal ID: KP2241 YP_002919002.1 internal ID: KP2242 YP_002919003.1 internal ID: KP2243 YP_002919004.1 internal ID: KP2244 YP_002919005.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2245 YP_002919006.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2246 YP_002919007.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2247 YP_002919008.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2248 YP_002919009.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction YP_002919010.1 catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate YP_002919011.1 internal ID: KP2252 YP_002919012.1 internal ID: KP2253 YP_002919013.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation YP_002919014.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism YP_002919015.1 periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP YP_002919016.1 3' incision activity; acts with UvrC YP_002919017.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_002919018.1 osmotically-inducible lipoprotein E; activator of ntr-like gene protein YP_002919019.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_002919020.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_002919021.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_002919022.1 represses the celABCDF-ydjC operon involved in carbon uptake YP_002919023.1 internal ID: KP2267 YP_002919024.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2268 YP_002919025.1 internal ID: KP2269 YP_002919026.1 internal ID: KP2270 YP_002919027.1 internal ID: KP2271 YP_002919028.1 internal ID: KP2272 YP_002919029.1 internal ID: KP2273 YP_002919030.1 internal ID: KP2274 YP_002919031.1 YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate YP_002919032.1 internal ID: KP2276 YP_002919033.1 internal ID: KP2277 YP_002919034.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space YP_002919035.1 Involved in cell division; probably involved in intracellular septation YP_002919036.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2280 YP_002919037.1 internal ID: KP2281 YP_002919038.1 receptor for colicin S4 YP_002919039.1 internal ID: KP2283 YP_002919040.1 Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein YP_002919041.1 internal ID: KP2285 YP_002919042.1 identified by Glimmer2; internal ID: KP2286 YP_002919043.1 internal ID: KP2287 YP_002919044.1 internal ID: KP2289 YP_002919045.1 internal ID: KP2290 YP_002919046.1 internal ID: KP2291 YP_002919047.1 internal ID: KP2292 YP_002919048.1 internal ID: KP2293 YP_002919049.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_002919050.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_002919051.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate YP_002919052.1 bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis YP_002919053.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_002919054.1 internal ID: KP2299 YP_002919055.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2300 YP_002919056.1 internal ID: KP2301 YP_002919057.1 internal ID: KP2302 YP_002919058.1 catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA YP_002919059.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide YP_002919060.1 internal ID: KP2305 YP_002919061.1 identified by Glimmer2; internal ID: KP2306 YP_002919062.1 SohB; periplasmic protein; member of the peptidase S49 family YP_002919063.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2309 YP_002919064.1 identified by Glimmer2; internal ID: KP2310 YP_002919065.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_002919066.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation YP_002919067.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2314 YP_002919068.1 Catalyzes the conversion of citrate to isocitrate YP_002919069.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate YP_002919070.1 internal ID: KP2317 YP_002919071.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2318 YP_002919072.1 internal ID: KP2319 YP_002919073.1 internal ID: KP2320 YP_002919074.1 involved in start site selection during the initiation of translation YP_002919075.1 internal ID: KP2322 YP_002919076.1 internal ID: KP2323 YP_002919077.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2324 YP_002919078.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction YP_002919079.1 internal ID: KP2326 YP_002919080.1 Catalyzes a key regulatory step in fatty acid biosynthesis YP_002919081.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2329 YP_002919082.1 internal ID: KP2330 YP_002919083.1 internal ID: KP2331 YP_002919084.1 internal ID: KP2332 YP_002919085.1 internal ID: KP2333 YP_002919086.1 internal ID: KP2334 YP_002919087.1 internal ID: KP2335 YP_002919088.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2336 YP_002919089.1 internal ID: KP2337 YP_002919090.1 internal ID: KP2338 YP_002919091.1 internal ID: KP2339 YP_002919092.1 internal ID: KP2340 YP_002919093.1 transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor YP_002919094.1 involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF YP_002919095.1 acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding YP_002919096.1 with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock YP_002919097.1 internal ID: KP2345 YP_002919098.1 internal ID: KP2346 YP_002919099.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2347 YP_002919100.1 internal ID: KP2348 YP_002919101.1 internal ID: KP2349 YP_002919102.1 regulates genes involved in the biosynthesis and transport of aromatic amino acids YP_002919103.1 internal ID: KP2351 YP_002919104.1 internal ID: KP2352 YP_002919105.1 internal ID: KP2353 YP_002919106.1 internal ID: KP2354 YP_002919107.1 identified by Glimmer2; internal ID: KP2355 YP_002919108.1 internal ID: KP2356 YP_002919109.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2357 YP_002919110.1 identified by Glimmer2; internal ID: KP2358 YP_002919111.1 identified by GeneMark.hmm; internal ID: KP2359 YP_002919112.1 identified by Glimmer2; internal ID: KP2360 YP_002919113.1 identified by Glimmer2; internal ID: KP2361 YP_002919114.1 identified by Glimmer2; internal ID: KP2362 YP_002919115.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2363 YP_002919116.1 identified by Glimmer2; internal ID: KP2364 YP_002919117.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2365 YP_002919118.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2366 YP_002919119.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2367 YP_002919120.1 identified by GeneMark.hmm; internal ID: KP2369 YP_002919121.1 identified by GeneMark.hmm; internal ID: KP2370 YP_002919122.1 internal ID: KP2371 YP_002919123.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2372 YP_002919124.1 internal ID: KP2373 YP_002919125.1 internal ID: KP2374 YP_002919126.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2375 YP_002919127.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2376 YP_002919128.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2377 YP_002919129.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2378 YP_002919130.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2379 YP_002919131.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2380 YP_002919132.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2381 YP_002919133.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2382 YP_002919134.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2383 YP_002919135.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2384 YP_002919136.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2385 YP_002919137.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2386 YP_002919138.1 internal ID: KP2387 YP_002919139.1 internal ID: KP2388 YP_002919140.1 internal ID: KP2389 YP_002919141.1 internal ID: KP2390 YP_002919142.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2392 YP_002919143.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2393 YP_002919144.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2395 YP_002919145.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2396 YP_002919146.1 internal ID: KP2397 YP_002919147.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2398 YP_002919148.1 internal ID: KP2399 YP_002919149.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2400 YP_002919150.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2401 YP_002919151.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2402 YP_002919152.1 identified by GeneMark.hmm; internal ID: KP2403 YP_002919153.1 internal ID: KP2404 YP_002919154.1 internal ID: KP2405 YP_002919155.1 internal ID: KP2406 YP_002919156.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2407 YP_002919157.1 identified by GeneMark.hmm; internal ID: KP2408 YP_002919158.1 internal ID: KP2409 YP_002919159.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2411 YP_002919160.1 internal ID: KP2412 YP_002919161.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2413 YP_002919162.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2414 YP_002919163.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2415 YP_002919164.1 identified by GeneMark.hmm; internal ID: KP2418 YP_002919165.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2419 YP_002919166.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2420 YP_002919167.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2421 YP_002919168.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2422 YP_002919169.1 internal ID: KP2423 YP_002919170.1 internal ID: KP2424 YP_002919171.1 internal ID: KP2425 YP_002919172.1 internal ID: KP2426 YP_002919173.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2427 YP_002919174.1 internal ID: KP2428 YP_002919175.1 internal ID: KP2429 YP_002919176.1 internal ID: KP2430 YP_002919177.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2431 YP_002919178.1 internal ID: KP2432 YP_002919179.1 internal ID: KP2433 YP_002919180.1 internal ID: KP2434 YP_002919181.1 internal ID: KP2435 YP_002919182.1 internal ID: KP2436 YP_002919183.1 internal ID: KP2437 YP_002919184.1 internal ID: KP2438 YP_002919185.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_002919186.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2442 YP_002919187.1 internal ID: KP2443 YP_002919188.1 internal ID: KP2444 YP_002919189.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2445 YP_002919190.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2446 YP_002919191.1 internal ID: KP2447 YP_002919192.1 internal ID: KP2448 YP_002919193.1 internal ID: KP2449 YP_002919194.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA YP_002919195.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_002919196.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2452 YP_002919197.1 identified by Glimmer2; internal ID: KP2453 YP_002919198.1 internal ID: KP2454 YP_002919199.1 internal ID: KP2455 YP_002919200.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2456 YP_002919201.1 internal ID: KP2457 YP_002919202.1 internal ID: KP2458 YP_002919203.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2459 YP_002919204.1 identified by Glimmer2; internal ID: KP2460 YP_002919205.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2461 YP_002919206.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2462 YP_002919207.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2463 YP_002919208.1 activator of genes involved in phenylacetic acid catabolism YP_002919209.1 internal ID: KP2465 YP_002919210.1 internal ID: KP2467 YP_002919211.1 internal ID: KP2468 YP_002919212.1 catalyzes the formation of phenylacetaldehyde from 2-phenylethylamine YP_002919213.1 catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA YP_002919214.1 identified by Glimmer2; internal ID: KP2471 YP_002919215.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA YP_002919216.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation YP_002919217.1 internal ID: KP2474 YP_002919218.1 internal ID: KP2475 YP_002919219.1 internal ID: KP2476 YP_002919220.1 internal ID: KP2477 YP_002919221.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_002919222.1 converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation YP_002919223.1 internal ID: KP2480 YP_002919224.1 catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA YP_002919225.1 internal ID: KP2482 YP_002919226.1 internal ID: KP2483 YP_002919227.1 internal ID: KP2484 YP_002919228.1 identified by Glimmer2; internal ID: KP2485 YP_002919229.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds YP_002919230.1 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain YP_002919231.1 internal ID: KP2488 YP_002919232.1 internal ID: KP2489 YP_002919233.1 internal ID: KP2490 YP_002919234.1 internal ID: KP2491 YP_002919235.1 internal ID: KP2492 YP_002919236.1 internal ID: KP2493 YP_002919237.1 internal ID: KP2494 YP_002919238.1 internal ID: KP2495 YP_002919239.1 identified by Glimmer2; internal ID: KP2496 YP_002919240.1 identified by Glimmer2; internal ID: KP2497 YP_002919241.1 catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate YP_002919242.1 internal ID: KP2499 YP_002919243.1 internal ID: KP2501 YP_002919244.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation YP_002919245.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism YP_002919246.1 internal ID: KP2505 YP_002919247.1 internal ID: KP2506 YP_002919248.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2507 YP_002919249.1 identified by Glimmer2; internal ID: KP2508 YP_002919250.1 NAD-linked YP_002919251.1 internal ID: KP2510 YP_002919252.1 internal ID: KP2511 YP_002919253.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2512 YP_002919254.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2513 YP_002919255.1 internal ID: KP2514 YP_002919256.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2515 YP_002919257.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2516 YP_002919258.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2517 YP_002919259.1 internal ID: KP2518 YP_002919260.1 internal ID: KP2519 YP_002919261.1 phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site YP_002919262.1 regulates malXY which are involved in maltose-glucose transport YP_002919263.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2523 YP_002919264.1 internal ID: KP2524 YP_002919265.1 internal ID: KP2525 YP_002919266.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_002919267.1 binds to DNA replication terminator sequences to prevent passage of replication forks YP_002919268.1 internal ID: KP2528 YP_002919269.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2530 YP_002919270.1 response regulator in two-component regulatory system with RstB YP_002919271.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2532 YP_002919272.1 internal ID: KP2533 YP_002919273.1 internal ID: KP2534 YP_002919274.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2535 YP_002919275.1 identified by Glimmer2; internal ID: KP2536 YP_002919276.1 identified by Glimmer2; internal ID: KP2537 YP_002919277.1 identified by Glimmer2; internal ID: KP2538 YP_002919278.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm YP_002919279.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme YP_002919280.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2541 YP_002919281.1 with UspC and UspD is involved in resistance to UV irradiation YP_002919282.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia YP_002919283.1 internal ID: KP2546 YP_002919284.1 identified by Glimmer2; internal ID: KP2547 YP_002919285.1 internal ID: KP2548 YP_002919286.1 internal ID: KP2549 YP_002919287.1 internal ID: KP2550 YP_002919288.1 internal ID: KP2551 YP_002919289.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2552 YP_002919290.1 internal ID: KP2553 YP_002919291.1 internal ID: KP2555 YP_002919292.1 internal ID: KP2556 YP_002919293.1 internal ID: KP2557 YP_002919294.1 internal ID: KP2558 YP_002919295.1 internal ID: KP2559 YP_002919296.1 internal ID: KP2560 YP_002919297.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2561 YP_002919298.1 internal ID: KP2562 YP_002919299.1 internal ID: KP2563 YP_002919300.1 identified by Glimmer2; internal ID: KP2564 YP_002919301.1 internal ID: KP2565 YP_002919302.1 internal ID: KP2566 YP_002919303.1 response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration YP_002919304.1 C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration YP_002919305.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2569 YP_002919306.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2570 YP_002919307.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate YP_002919308.1 internal ID: KP2572 YP_002919309.1 internal ID: KP2573 YP_002919310.1 Catalyzes the transfer of 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A to the apo-acyl carrier protein of malonate dehydrogenase to form holo-acyl carrier protein YP_002919311.1 internal ID: KP2575 YP_002919312.1 internal ID: KP2576 YP_002919313.1 The beta subunit catalyzes the decarboxylation of the malonyl moiety on coenzyme A YP_002919314.1 internal ID: KP2579 YP_002919315.1 internal ID: KP2580 YP_002919316.1 internal ID: KP2581 YP_002919317.1 transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes YP_002919318.1 with MdtI is involved in resistance to deoxycholate , nalidixic acid, fosfomycin, and SDS YP_002919319.1 with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS YP_002919320.1 identified by Glimmer2; internal ID: KP2585 YP_002919321.1 internal ID: KP2586 YP_002919322.1 identified by Glimmer2; internal ID: KP2587 YP_002919323.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2589 YP_002919324.1 identified by Glimmer2; internal ID: KP2590 YP_002919325.1 internal ID: KP2591 YP_002919326.1 internal ID: KP2593 YP_002919327.1 identified by Glimmer2; internal ID: KP2594 YP_002919328.1 internal ID: KP2595 YP_002919329.1 internal ID: KP2596 YP_002919330.1 internal ID: KP2597 YP_002919331.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_002919332.1 internal ID: KP2599 YP_002919333.1 binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane YP_002919334.1 internal ID: KP2601 YP_002919335.1 internal ID: KP2602 YP_002919336.1 internal ID: KP2603 YP_002919337.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2604 YP_002919338.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2605 YP_002919339.1 internal ID: KP2606 YP_002919340.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2607 YP_002919341.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2608 YP_002919342.1 internal ID: KP2609 YP_002919343.1 internal ID: KP2610 YP_002919344.1 internal ID: KP2611 YP_002919345.1 internal ID: KP2612 YP_002919346.1 NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine YP_002919347.1 internal ID: KP2614 YP_002919348.1 identified by GeneMark.hmm; internal ID: KP2615 YP_002919349.1 internal ID: KP2616 YP_002919350.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2617 YP_002919351.1 identified by Glimmer2; internal ID: KP2618 YP_002919352.1 internal ID: KP2619 YP_002919353.1 identified by Glimmer2; internal ID: KP2620 YP_002919354.1 identified by Glimmer2; internal ID: KP2621 YP_002919355.1 internal ID: KP2622 YP_002919356.1 internal ID: KP2623 YP_002919357.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2624 YP_002919358.1 identified by Glimmer2; internal ID: KP2625 YP_002919359.1 internal ID: KP2626 YP_002919360.1 internal ID: KP2627 YP_002919361.1 member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function YP_002919362.1 internal ID: KP2629 YP_002919363.1 internal ID: KP2630 YP_002919364.1 internal ID: KP2631 YP_002919365.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2632 YP_002919366.1 internal ID: KP2633 YP_002919367.1 internal ID: KP2635 YP_002919368.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2636 YP_002919369.1 internal ID: KP2637 YP_002919370.1 internal ID: KP2638 YP_002919371.1 forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon YP_002919372.1 transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer YP_002919373.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2641 YP_002919374.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2642 YP_002919375.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2643 YP_002919376.1 upregulated by FixLJ/FixK under oxygen limitation; involved in regulation of genes involved in carbon and amino acid metabolism YP_002919377.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2646 YP_002919378.1 catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate YP_002919379.1 internal ID: KP2648 YP_002919380.1 internal ID: KP2650 YP_002919381.1 internal ID: KP2651 YP_002919382.1 internal ID: KP2652 YP_002919383.1 internal ID: KP2653 YP_002919384.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2654 YP_002919385.1 YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters YP_002919386.1 internal ID: KP2656 YP_002919387.1 internal ID: KP2657 YP_002919388.1 transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF YP_002919389.1 Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes YP_002919390.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2660 YP_002919391.1 protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function YP_002919392.1 internal ID: KP2663 YP_002919393.1 internal ID: KP2664 YP_002919394.1 internal ID: KP2665 YP_002919395.1 internal ID: KP2666 YP_002919396.1 internal ID: KP2667 YP_002919397.1 internal ID: KP2668 YP_002919398.1 internal ID: KP2669 YP_002919399.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_002919400.1 internal ID: KP2671 YP_002919401.1 internal ID: KP2672 YP_002919402.1 internal ID: KP2673 YP_002919403.1 internal ID: KP2674 YP_002919404.1 in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase YP_002919405.1 catalyzes the formation of glutamate from glutamine YP_002919406.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2677 YP_002919407.1 internal ID: KP2678 YP_002919408.1 internal ID: KP2679 YP_002919409.1 catalyzes the formation of D-tagaturonate from D-altronate YP_002919410.1 internal ID: KP2681 YP_002919411.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2682 YP_002919412.1 identified by Glimmer2; internal ID: KP2683 YP_002919413.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2684 YP_002919414.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2686 YP_002919415.1 internal ID: KP2687 YP_002919416.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2688 YP_002919417.1 internal ID: KP2689 YP_002919418.1 catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate YP_002919419.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2691 YP_002919420.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2692 YP_002919421.1 internal ID: KP2693 YP_002919422.1 internal ID: KP2694 YP_002919423.1 internal ID: KP2695 YP_002919424.1 internal ID: KP2696 YP_002919425.1 internal ID: KP2697 YP_002919426.1 internal ID: KP2698 YP_002919427.1 internal ID: KP2699 YP_002919428.1 internal ID: KP2700 YP_002919429.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2701 YP_002919430.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2702 YP_002919431.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2703 YP_002919432.1 internal ID: KP2704 YP_002919433.1 internal ID: KP2705 YP_002919434.1 internal ID: KP2706 YP_002919435.1 internal ID: KP2707 YP_002919436.1 internal ID: KP2708 YP_002919437.1 internal ID: KP2709 YP_002919438.1 internal ID: KP2710 YP_002919439.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2711 YP_002919440.1 internal ID: KP2712 YP_002919441.1 internal ID: KP2713 YP_002919442.1 internal ID: KP2714 YP_002919443.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2715 YP_002919444.1 internal ID: KP2716 YP_002919445.1 internal ID: KP2717 YP_002919446.1 internal ID: KP2718 YP_002919447.1 internal ID: KP2719 YP_002919448.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2720 YP_002919449.1 internal ID: KP2721 YP_002919450.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2722 YP_002919451.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2723 YP_002919452.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2724 YP_002919453.1 internal ID: KP2725 YP_002919454.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2726 YP_002919455.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2728 YP_002919456.1 internal ID: KP2729 YP_002919457.1 internal ID: KP2730 YP_002919458.1 identified by Glimmer2; internal ID: KP2731 YP_002919459.1 identified by Glimmer2; internal ID: KP2732 YP_002919460.1 identified by Glimmer2; internal ID: KP2733 YP_002919461.1 internal ID: KP2734 YP_002919462.1 internal ID: KP2735 YP_002919463.1 internal ID: KP2736 YP_002919464.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2737 YP_002919465.1 internal ID: KP2738 YP_002919466.1 internal ID: KP2739 YP_002919467.1 internal ID: KP2740 YP_002919468.1 internal ID: KP2741 YP_002919469.1 internal ID: KP2742 YP_002919470.1 internal ID: KP2743 YP_002919471.1 internal ID: KP2744 YP_002919472.1 internal ID: KP2745 YP_002919473.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_002919474.1 internal ID: KP2747 YP_002919475.1 internal ID: KP2748 YP_002919476.1 internal ID: KP2749 YP_002919477.1 internal ID: KP2750 YP_002919478.1 internal ID: KP2751 YP_002919479.1 internal ID: KP2752 YP_002919480.1 internal ID: KP2753 YP_002919481.1 identified by Glimmer2; internal ID: KP2754 YP_002919482.1 internal ID: KP2755 YP_002919483.1 internal ID: KP2756 YP_002919484.1 internal ID: KP2757 YP_002919485.1 identified by Glimmer2; internal ID: KP2758 YP_002919486.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2759 YP_002919487.1 internal ID: KP2760 YP_002919488.1 identified by GeneMark.hmm; internal ID: KP2761 YP_002919489.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2762 YP_002919490.1 internal ID: KP2764 YP_002919491.1 internal ID: KP2765 YP_002919492.1 internal ID: KP2766 YP_002919493.1 internal ID: KP2767 YP_002919494.1 internal ID: KP2768 YP_002919495.1 internal ID: KP2769 YP_002919496.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2770 YP_002919497.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2771 YP_002919498.1 internal ID: KP2772 YP_002919499.1 internal ID: KP2773 YP_002919500.1 internal ID: KP2774 YP_002919501.1 internal ID: KP2775 YP_002919502.1 internal ID: KP2776 YP_002919503.1 internal ID: KP2777 YP_002919504.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2778 YP_002919505.1 internal ID: KP2779 YP_002919506.1 internal ID: KP2780 YP_002919507.1 internal ID: KP2781 YP_002919508.1 internal ID: KP2783 YP_002919509.1 internal ID: KP2784 YP_002919510.1 internal ID: KP2785 YP_002919511.1 internal ID: KP2786 YP_002919512.1 internal ID: KP2787 YP_002919513.1 internal ID: KP2788 YP_002919514.1 internal ID: KP2790 YP_002919515.1 internal ID: KP2791 YP_002919516.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr YP_002919517.1 internal ID: KP2793 YP_002919518.1 internal ID: KP2794 YP_002919519.1 internal ID: KP2795 YP_002919520.1 internal ID: KP2796 YP_002919521.1 internal ID: KP2797 YP_002919522.1 internal ID: KP2798 YP_002919523.1 internal ID: KP2799 YP_002919524.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2800 YP_002919525.1 internal ID: KP2801 YP_002919526.1 internal ID: KP2802 YP_002919527.1 internal ID: KP2803 YP_002919528.1 internal ID: KP2805 YP_002919529.1 internal ID: KP2806 YP_002919530.1 internal ID: KP2807 YP_002919531.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_002919532.1 internal ID: KP2809 YP_002919533.1 internal ID: KP2810 YP_002919534.1 internal ID: KP2811 YP_002919535.1 internal ID: KP2812 YP_002919536.1 internal ID: KP2814 YP_002919537.1 internal ID: KP2815 YP_002919538.1 internal ID: KP2816 YP_002919539.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2817 YP_002919540.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_002919541.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2820 YP_002919542.1 internal ID: KP2821 YP_002919543.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_002919544.1 internal ID: KP2823 YP_002919545.1 internal ID: KP2824 YP_002919546.1 internal ID: KP2825 YP_002919547.1 internal ID: KP2826 YP_002919548.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2827 YP_002919549.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2828 YP_002919550.1 internal ID: KP2829 YP_002919551.1 Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group YP_002919552.1 identified by GeneMark.hmm; internal ID: KP2832 YP_002919553.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2833 YP_002919554.1 internal ID: KP2834 YP_002919555.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2835 YP_002919556.1 internal ID: KP2836 YP_002919557.1 internal ID: KP2837 YP_002919558.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2838 YP_002919559.1 internal ID: KP2839 YP_002919560.1 internal ID: KP2840 YP_002919561.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2841 YP_002919562.1 internal ID: KP2842 YP_002919563.1 internal ID: KP2844 YP_002919564.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2845 YP_002919565.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2846 YP_002919566.1 internal ID: KP2847 YP_002919567.1 internal ID: KP2849 YP_002919568.1 internal ID: KP2850 YP_002919569.1 internal ID: KP2851 YP_002919570.1 catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde YP_002919571.1 internal ID: KP2853 YP_002919572.1 internal ID: KP2854 YP_002919573.1 internal ID: KP2856 YP_002919574.1 internal ID: KP2857 YP_002919575.1 internal ID: KP2858 YP_002919576.1 internal ID: KP2859 YP_002919577.1 internal ID: KP2860 YP_002919578.1 Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis; probably provides the glutamate and tyrosine residues that are cross-linked and modified to form the coenzyme YP_002919579.1 possibly involved in transport of pyrroloquinoline quinone transport YP_002919580.1 Required in the synthesis of PPQ, but its exact function is unknown YP_002919581.1 internal ID: KP2863 YP_002919582.1 internal ID: KP2864 YP_002919583.1 internal ID: KP2865 YP_002919584.1 Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group YP_002919585.1 internal ID: KP2867 YP_002919586.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2868 YP_002919587.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2869 YP_002919588.1 internal ID: KP2870 YP_002919589.1 internal ID: KP2871 YP_002919590.1 internal ID: KP2872 YP_002919591.1 internal ID: KP2873 YP_002919592.1 internal ID: KP2874 YP_002919593.1 internal ID: KP2875 YP_002919594.1 internal ID: KP2877 YP_002919595.1 identified by Glimmer2; internal ID: KP2878 YP_002919596.1 internal ID: KP2879 YP_002919597.1 internal ID: KP2880 YP_002919598.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2881 YP_002919599.1 internal ID: KP2882 YP_002919600.1 internal ID: KP2883 YP_002919601.1 internal ID: KP2884 YP_002919602.1 internal ID: KP2885 YP_002919603.1 internal ID: KP2886 YP_002919604.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2887 YP_002919605.1 internal ID: KP2888 YP_002919606.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2889 YP_002919607.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2890 YP_002919608.1 internal ID: KP2891 YP_002919609.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2893 YP_002919610.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2894 YP_002919611.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2895 YP_002919612.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2896 YP_002919613.1 internal ID: KP2897 YP_002919614.1 internal ID: KP2898 YP_002919615.1 internal ID: KP2900 YP_002919616.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2901 YP_002919617.1 identified by Glimmer2; internal ID: KP2902 YP_002919618.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2903 YP_002919619.1 internal ID: KP2904 YP_002919620.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2905 YP_002919621.1 internal ID: KP2906 YP_002919622.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2907 YP_002919623.1 protein D; stationary-phase-induced ribosome-associated; in Escherichia coli this protein becomes associated with the ribosome; expression increases during stationary phase YP_002919624.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate YP_002919625.1 internal ID: KP2911 YP_002919626.1 internal ID: KP2912 YP_002919627.1 internal ID: KP2913 YP_002919628.1 internal ID: KP2914 YP_002919629.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs YP_002919630.1 internal ID: KP2917 YP_002919631.1 internal ID: KP2918 YP_002919632.1 internal ID: KP2919 YP_002919633.1 internal ID: KP2920 YP_002919634.1 internal ID: KP2921 YP_002919635.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2923 YP_002919636.1 member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers YP_002919637.1 internal ID: KP2925 YP_002919638.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2926 YP_002919639.1 identified by GeneMark.hmm; internal ID: KP2927 YP_002919640.1 identified by GeneMark.hmm; internal ID: KP2928 YP_002919641.1 nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase YP_002919642.1 internal ID: KP2930 YP_002919643.1 internal ID: KP2931 YP_002919644.1 internal ID: KP2933 YP_002919645.1 catalyzes the degradation of 2-hydro-1,2-dihydroxy benzoate to catechol YP_002919646.1 internal ID: KP2935 YP_002919647.1 internal ID: KP2936 YP_002919648.1 internal ID: KP2937 YP_002919649.1 internal ID: KP2938 YP_002919650.1 internal ID: KP2939 YP_002919651.1 internal ID: KP2940 YP_002919652.1 internal ID: KP2941 YP_002919653.1 internal ID: KP2942 YP_002919654.1 internal ID: KP2943 YP_002919655.1 internal ID: KP2944 YP_002919656.1 internal ID: KP2945 YP_002919657.1 internal ID: KP2946 YP_002919658.1 internal ID: KP2947 YP_002919659.1 internal ID: KP2948 YP_002919660.1 internal ID: KP2949 YP_002919661.1 internal ID: KP2950 YP_002919662.1 internal ID: KP2951 YP_002919663.1 internal ID: KP2952 YP_002919664.1 internal ID: KP2953 YP_002919665.1 internal ID: KP2954 YP_002919666.1 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown YP_002919667.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2956 YP_002919668.1 internal ID: KP2957 YP_002919669.1 internal ID: KP2958 YP_002919670.1 internal ID: KP2960 YP_002919671.1 internal ID: KP2961 YP_002919672.1 internal ID: KP2962 YP_002919673.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2963 YP_002919674.1 internal ID: KP2964 YP_002919675.1 internal ID: KP2966 YP_002919676.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2967 YP_002919677.1 internal ID: KP2968 YP_002919678.1 internal ID: KP2969 YP_002919679.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2970 YP_002919680.1 internal ID: KP2971 YP_002919681.1 internal ID: KP2972 YP_002919682.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2973 YP_002919683.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2974 YP_002919684.1 Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific YP_002919685.1 internal ID: KP2976 YP_002919686.1 internal ID: KP2977 YP_002919687.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2978 YP_002919688.1 internal ID: KP2979 YP_002919689.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2980 YP_002919690.1 internal ID: KP2981 YP_002919691.1 internal ID: KP2982 YP_002919692.1 internal ID: KP2983 YP_002919693.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP2985 YP_002919694.1 identified by Glimmer2; internal ID: KP2986 YP_002919695.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2987 YP_002919696.1 identified by Glimmer2; internal ID: KP2988 YP_002919697.1 catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation YP_002919698.1 internal ID: KP2990 YP_002919699.1 internal ID: KP2991 YP_002919700.1 internal ID: KP2992 YP_002919701.1 internal ID: KP2993 YP_002919702.1 internal ID: KP2994 YP_002919703.1 identified by Glimmer2; internal ID: KP2995 YP_002919704.1 internal ID: KP2996 YP_002919705.1 internal ID: KP2997 YP_002919706.1 identified by GeneMark and GeneMark.hmm; internal ID: KP2998 YP_002919707.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP2999 YP_002919708.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3000 YP_002919709.1 internal ID: KP3001 YP_002919710.1 internal ID: KP3002 YP_002919711.1 internal ID: KP3003 YP_002919712.1 internal ID: KP3004 YP_002919713.1 internal ID: KP3005 YP_002919714.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3006 YP_002919715.1 with TehA confers resistance to tellurite YP_002919716.1 internal ID: KP3008 YP_002919717.1 internal ID: KP3009 YP_002919718.1 internal ID: KP3010 YP_002919719.1 involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans YP_002919720.1 internal ID: KP3012 YP_002919721.1 internal ID: KP3013 YP_002919722.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3014 YP_002919723.1 internal ID: KP3015 YP_002919724.1 internal ID: KP3016 YP_002919725.1 internal ID: KP3017 YP_002919726.1 internal ID: KP3018 YP_002919727.1 internal ID: KP3020 YP_002919728.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3021 YP_002919729.1 B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm YP_002919730.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3023 YP_002919731.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3024 YP_002919732.1 internal ID: KP3025 YP_002919733.1 internal ID: KP3026 YP_002919734.1 internal ID: KP3027 YP_002919735.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3028 YP_002919736.1 internal ID: KP3029 YP_002919737.1 internal ID: KP3030 YP_002919738.1 YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes YP_002919739.1 internal ID: KP3033 YP_002919740.1 internal ID: KP3034 YP_002919741.1 internal ID: KP3036 YP_002919742.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_002919743.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_002919744.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents YP_002919745.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen YP_002919746.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase YP_002919747.1 DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines YP_002919748.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3043 YP_002919749.1 mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation YP_002919750.1 internal ID: KP3045 YP_002919751.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal YP_002919752.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_002919753.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate YP_002919754.1 MliC; membrane-bound lysozyme inhibitor of c-type lysozyme YP_002919755.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_002919756.1 internal ID: KP3051 YP_002919757.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3053 YP_002919758.1 Transcription regulator that can both activate or repress expression YP_002919759.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3055 YP_002919760.1 internal ID: KP3056 YP_002919761.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3057 YP_002919762.1 SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water YP_002919763.1 internal ID: KP3059 YP_002919764.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3060 YP_002919765.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3061 YP_002919766.1 FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide YP_002919767.1 Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione YP_002919768.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) YP_002919769.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3065 YP_002919770.1 internal ID: KP3066 YP_002919771.1 internal ID: KP3067 YP_002919772.1 SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals YP_002919773.1 internal ID: KP3069 YP_002919774.1 binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers YP_002919775.1 internal ID: KP3072 YP_002919776.1 uncharacterized member of the major facilitator superfamily (MFS) YP_002919777.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge YP_002919778.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_002919779.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones YP_002919780.1 internal ID: KP3077 YP_002919782.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3079 YP_002919783.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3080 YP_002919784.1 internal ID: KP3081 YP_002919785.1 internal ID: KP3082 YP_002919786.1 internal ID: KP3083 YP_002919787.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3084 YP_002919788.1 internal ID: KP3085 YP_002919789.1 identified by GeneMark.hmm; internal ID: KP3086 YP_002919790.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3087 YP_002919791.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3088 YP_002919792.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3089 YP_002919793.1 internal ID: KP3090 YP_002919794.1 internal ID: KP3091 YP_002919795.1 internal ID: KP3092 YP_002919796.1 internal ID: KP3093 YP_002919797.1 internal ID: KP3094 YP_002919798.1 internal ID: KP3095 YP_002919799.1 internal ID: KP3096 YP_002919800.1 internal ID: KP3097 YP_002919801.1 internal ID: KP3098 YP_002919802.1 internal ID: KP3099 YP_002919803.1 identified by Glimmer2; internal ID: KP3100 YP_002919804.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3101 YP_002919805.1 internal ID: KP3102 YP_002919806.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3103 YP_002919807.1 internal ID: KP3104 YP_002919808.1 internal ID: KP3105 YP_002919809.1 internal ID: KP3106 YP_002919810.1 internal ID: KP3107 YP_002919811.1 internal ID: KP3108 YP_002919812.1 internal ID: KP3109 YP_002919813.1 internal ID: KP3110 YP_002919814.1 internal ID: KP3111 YP_002919815.1 internal ID: KP3112 YP_002919816.1 internal ID: KP3114 YP_002919817.1 internal ID: KP3115 YP_002919818.1 internal ID: KP3116 YP_002919819.1 internal ID: KP3117 YP_002919820.1 internal ID: KP3120 YP_002919821.1 internal ID: KP3121 YP_002919822.1 internal ID: KP3122 YP_002919823.1 internal ID: KP3123 YP_002919824.1 internal ID: KP3125 YP_002919825.1 identified by Glimmer2; internal ID: KP3126 YP_002919826.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3127 YP_002919827.1 internal ID: KP3128 YP_002919828.1 internal ID: KP3129 YP_002919829.1 internal ID: KP3130 YP_002919830.1 internal ID: KP3131 YP_002919831.1 internal ID: KP3132 YP_002919832.1 internal ID: KP3133 YP_002919833.1 catalyzes the formation of acetoacetate from 3-hydroxybutyrate YP_002919834.1 internal ID: KP3135 YP_002919835.1 internal ID: KP3136 YP_002919836.1 catalyzes the formation of 2-acetolactate from pyruvate in stationary phase YP_002919837.1 internal ID: KP3140 YP_002919838.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3141 YP_002919839.1 identified by GeneMark.hmm; internal ID: KP3142 YP_002919840.1 internal ID: KP3143 YP_002919841.1 internal ID: KP3145 YP_002919842.1 identified by GeneMark.hmm; internal ID: KP3146 YP_002919843.1 internal ID: KP3147 YP_002919844.1 internal ID: KP3148 YP_002919845.1 internal ID: KP3149 YP_002919846.1 internal ID: KP3150 YP_002919847.1 internal ID: KP3151 YP_002919848.1 internal ID: KP3152 YP_002919849.1 internal ID: KP3153 YP_002919850.1 internal ID: KP3154 YP_002919851.1 internal ID: KP3155 YP_002919852.1 ATP-binding protein; required for proper cytochrome c maturation YP_002919853.1 internal ID: KP3157 YP_002919854.1 internal ID: KP3158 YP_002919855.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3160 YP_002919856.1 internal ID: KP3161 YP_002919857.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3162 YP_002919858.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3163 YP_002919859.1 internal ID: KP3164 YP_002919860.1 internal ID: KP3165 YP_002919861.1 internal ID: KP3166 YP_002919862.1 internal ID: KP3167 YP_002919863.1 internal ID: KP3168 YP_002919864.1 internal ID: KP3169 YP_002919865.1 internal ID: KP3170 YP_002919866.1 internal ID: KP3171 YP_002919867.1 identified by Glimmer2; internal ID: KP3172 YP_002919868.1 internal ID: KP3173 YP_002919869.1 internal ID: KP3174 YP_002919870.1 internal ID: KP3175 YP_002919871.1 identified by Glimmer2; internal ID: KP3176 YP_002919872.1 internal ID: KP3177 YP_002919873.1 internal ID: KP3178 YP_002919874.1 internal ID: KP3179 YP_002919875.1 internal ID: KP3180 YP_002919876.1 internal ID: KP3181 YP_002919877.1 internal ID: KP3182 YP_002919878.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3183 YP_002919879.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3184 YP_002919880.1 internal ID: KP3186 YP_002919881.1 internal ID: KP3187 YP_002919882.1 internal ID: KP3189 YP_002919883.1 internal ID: KP3190 YP_002919884.1 internal ID: KP3191 YP_002919885.1 internal ID: KP3192 YP_002919886.1 internal ID: KP3194 YP_002919887.1 internal ID: KP3195 YP_002919888.1 internal ID: KP3196 YP_002919889.1 internal ID: KP3198 YP_002919890.1 internal ID: KP3199 YP_002919891.1 internal ID: KP3200 YP_002919892.1 internal ID: KP3202 YP_002919893.1 internal ID: KP3203 YP_002919894.1 internal ID: KP3204 YP_002919895.1 internal ID: KP3205 YP_002919896.1 internal ID: KP3206 YP_002919897.1 internal ID: KP3207 YP_002919898.1 internal ID: KP3208 YP_002919899.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3209 YP_002919900.1 internal ID: KP3211 YP_002919901.1 internal ID: KP3212 YP_002919902.1 catalyzes the formation of acetyl-CoA from acetalaldehyde YP_002919903.1 catalyzes the formation of 2-keto-4-hydroxypentanoic acid from 2-hydroxypentadienoic acid YP_002919904.1 internal ID: KP3215 YP_002919905.1 catalyzes the cleavage of 3-(2,3-dihydroxyphenyl) propionate into 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate; part of the 3-phenylpropionic acid degradation pathway; member of the protocatechuate 4,5-dioxygenase family YP_002919906.1 catalyzes the formation of 3-(2,3-dihydroxyphenyl)propionate from 3-(3-hydroxyphenyl)propionate YP_002919907.1 activator of 3-phenylpropionic acid catabolism YP_002919908.1 internal ID: KP3219 YP_002919909.1 internal ID: KP3220 YP_002919910.1 internal ID: KP3221 YP_002919911.1 internal ID: KP3222 YP_002919912.1 internal ID: KP3223 YP_002919913.1 internal ID: KP3224 YP_002919914.1 internal ID: KP3225 YP_002919915.1 internal ID: KP3226 YP_002919916.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3227 YP_002919917.1 identified by Glimmer2; internal ID: KP3228 YP_002919918.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_002919919.1 internal ID: KP3230 YP_002919920.1 internal ID: KP3231 YP_002919921.1 Acts with SufS to catalyze the formation of L-alanine from L-cysteine YP_002919922.1 catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine YP_002919923.1 with SufBC activates cysteine desulfurase SufS YP_002919924.1 part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE YP_002919925.1 with SufCD activates cysteine desulfurase SufS YP_002919926.1 functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein YP_002919927.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3238 YP_002919928.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3239 YP_002919929.1 internal ID: KP3240 YP_002919930.1 internal ID: KP3241 YP_002919931.1 internal ID: KP3242 YP_002919932.1 internal ID: KP3243 YP_002919933.1 internal ID: KP3244 YP_002919934.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3245 YP_002919935.1 internal ID: KP3246 YP_002919936.1 internal ID: KP3247 YP_002919937.1 internal ID: KP3248 YP_002919938.1 internal ID: KP3249 YP_002919939.1 internal ID: KP3250 YP_002919940.1 catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate YP_002919941.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3252 YP_002919942.1 identified by Glimmer2; internal ID: KP3253 YP_002919943.1 identified by GeneMark.hmm; internal ID: KP3254 YP_002919944.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3255 YP_002919945.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3256 YP_002919946.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3258 YP_002919947.1 internal ID: KP3259 YP_002919948.1 YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function YP_002919949.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_002919950.1 identified by Glimmer2; internal ID: KP3262 YP_002919951.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3264 YP_002919952.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate YP_002919953.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3266 YP_002919954.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3267 YP_002919955.1 internal ID: KP3268 YP_002919956.1 ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell YP_002919957.1 similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane YP_002919958.1 internal ID: KP3272 YP_002919959.1 with BtuD and BtuF transports vitamin B12 into the cell YP_002919960.1 internal ID: KP3274 YP_002919961.1 internal ID: KP3275 YP_002919962.1 internal ID: KP3276 YP_002919963.1 internal ID: KP3277 YP_002919964.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_002919965.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_002919966.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_002919967.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_002919968.1 internal ID: KP3282 YP_002919969.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_002919970.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002919971.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3286 YP_002919972.1 identified by Glimmer2; internal ID: KP3288 YP_002919973.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3289 YP_002919974.1 internal ID: KP3290 YP_002919975.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3291 YP_002919976.1 internal ID: KP3292 YP_002919977.1 membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins YP_002919978.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity YP_002919979.1 identified by Glimmer2; internal ID: KP3296 YP_002919980.1 identified by Glimmer2; internal ID: KP3297 YP_002919981.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3298 YP_002919982.1 identified by Glimmer2; internal ID: KP3299 YP_002919983.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3300 YP_002919984.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) YP_002919985.1 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein YP_002919986.1 internal ID: KP3303 YP_002919987.1 internal ID: KP3304 YP_002919988.1 internal ID: KP3305 YP_002919989.1 internal ID: KP3306 YP_002919990.1 internal ID: KP3307 YP_002919991.1 internal ID: KP3308 YP_002919992.1 internal ID: KP3309 YP_002919993.1 identified by Glimmer2; internal ID: KP3310 YP_002919994.1 internal ID: KP3311 YP_002919995.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_002919996.1 identified by Glimmer2; internal ID: KP3313 YP_002919997.1 internal ID: KP3314 YP_002919998.1 together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose YP_002919999.1 internal ID: KP3316 YP_002920000.1 internal ID: KP3317 YP_002920001.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3318 YP_002920002.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_002920003.1 internal ID: KP3320 YP_002920004.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3321 YP_002920005.1 internal ID: KP3322 YP_002920006.1 internal ID: KP3323 YP_002920007.1 internal ID: KP3324 YP_002920008.1 internal ID: KP3325 YP_002920009.1 identified by Glimmer2; internal ID: KP3326 YP_002920010.1 internal ID: KP3327 YP_002920011.1 internal ID: KP3328 YP_002920012.1 two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase YP_002920013.1 internal ID: KP3330 YP_002920014.1 internal ID: KP3331 YP_002920015.1 internal ID: KP3332 YP_002920016.1 internal ID: KP3333 YP_002920017.1 internal ID: KP3334 YP_002920018.1 internal ID: KP3335 YP_002920019.1 internal ID: KP3337 YP_002920020.1 internal ID: KP3338 YP_002920021.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3339 YP_002920022.1 identified by Glimmer2; internal ID: KP3340 YP_002920023.1 internal ID: KP3341 YP_002920024.1 in Escherichia coli this protein putatively regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions YP_002920025.1 internal ID: KP3343 YP_002920026.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_002920027.1 internal ID: KP3346 YP_002920028.1 internal ID: KP3347 YP_002920029.1 HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB YP_002920030.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_002920031.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_002920032.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein YP_002920033.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_002920034.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_002920035.1 putative role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport YP_002920036.1 internal ID: KP3357 YP_002920037.1 YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function YP_002920038.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_002920039.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_002920040.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3362 YP_002920041.1 internal ID: KP3363 YP_002920042.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3364 YP_002920043.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3366 YP_002920044.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3367 YP_002920045.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3368 YP_002920046.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3369 YP_002920047.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3370 YP_002920048.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3371 YP_002920049.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3372 YP_002920050.1 identified by GeneMark.hmm; internal ID: KP3373 YP_002920051.1 identified by Glimmer2; internal ID: KP3374 YP_002920052.1 identified by GeneMark.hmm; internal ID: KP3375 YP_002920053.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3376 YP_002920054.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3378 YP_002920055.1 internal ID: KP3379 YP_002920056.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3380 YP_002920057.1 internal ID: KP3381 YP_002920058.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3382 YP_002920059.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3383 YP_002920060.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3384 YP_002920061.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3385 YP_002920062.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3386 YP_002920063.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3387 YP_002920064.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3388 YP_002920065.1 internal ID: KP3389 YP_002920066.1 internal ID: KP3390 YP_002920067.1 internal ID: KP3392 YP_002920068.1 internal ID: KP3393 YP_002920069.1 internal ID: KP3394 YP_002920070.1 internal ID: KP3395 YP_002920071.1 internal ID: KP3396 YP_002920072.1 internal ID: KP3397 YP_002920073.1 internal ID: KP3399 YP_002920074.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_002920075.1 internal ID: KP3401 YP_002920076.1 internal ID: KP3402 YP_002920077.1 internal ID: KP3403 YP_002920078.1 internal ID: KP3404 YP_002920079.1 internal ID: KP3406 YP_002920080.1 internal ID: KP3407 YP_002920081.1 internal ID: KP3408 YP_002920082.1 catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism YP_002920083.1 involved in the import of threonine and serine in combination with the import of a proton YP_002920084.1 catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic YP_002920085.1 regulates the tdcABCDEFG operon which is involved in amino acid degradation YP_002920086.1 internal ID: KP3414 YP_002920087.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3415 YP_002920088.1 internal ID: KP3416 YP_002920089.1 internal ID: KP3417 YP_002920090.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3418 YP_002920091.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3421 YP_002920092.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3422 YP_002920093.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3423 YP_002920094.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3424 YP_002920095.1 identified by Glimmer2; internal ID: KP3425 YP_002920096.1 periplasmic; catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell YP_002920097.1 internal ID: KP3427 YP_002920098.1 internal ID: KP3428 YP_002920099.1 catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine YP_002920100.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli YP_002920101.1 internal ID: KP3431 YP_002920102.1 catalyzes the oxidative deamination of D-amino acids YP_002920103.1 identified by Glimmer2; internal ID: KP3434 YP_002920104.1 internal ID: KP3433 YP_002920105.1 Multifunctional regulator of fatty acid metabolism YP_002920106.1 involved in regulation of intracellular pH under alkaline conditions YP_002920107.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein YP_002920108.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3439 YP_002920109.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3440 YP_002920110.1 internal ID: KP3441 YP_002920111.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3442 YP_002920112.1 blocks the formation of polar Z-ring septums YP_002920113.1 ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums YP_002920114.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell YP_002920115.1 internal ID: KP3446 YP_002920116.1 Activates fatty acids by binding to coenzyme A YP_002920117.1 internal ID: KP3448 YP_002920118.1 internal ID: KP3449 YP_002920119.1 internal ID: KP3450 YP_002920120.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3451 YP_002920121.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3452 YP_002920122.1 internal ID: KP3453 YP_002920123.1 internal ID: KP3454 YP_002920124.1 internal ID: KP3455 YP_002920125.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3456 YP_002920126.1 internal ID: KP3457 YP_002920127.1 internal ID: KP3458 YP_002920128.1 internal ID: KP3459 YP_002920129.1 hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel YP_002920130.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3461 YP_002920131.1 internal ID: KP3462 YP_002920132.1 internal ID: KP3463 YP_002920133.1 internal ID: KP3464 YP_002920134.1 internal ID: KP3465 YP_002920135.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3466 YP_002920136.1 identified by Glimmer2; internal ID: KP3468 YP_002920137.1 internal ID: KP3469 YP_002920138.1 internal ID: KP3470 YP_002920139.1 internal ID: KP3471 YP_002920140.1 putative metalloprotease YP_002920141.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 YP_002920142.1 affects solute and DNA transport through an unknown mechanism YP_002920143.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3475 YP_002920144.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3476 YP_002920145.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3477 YP_002920146.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA YP_002920147.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3479 YP_002920148.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3480 YP_002920149.1 Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins YP_002920150.1 internal ID: KP3482 YP_002920151.1 identified by Glimmer2; internal ID: KP3483 YP_002920152.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3484 YP_002920153.1 internal ID: KP3485 YP_002920154.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3486 YP_002920155.1 internal ID: KP3487 YP_002920156.1 3'-5' exonuclease activity on single or double-strand DNA YP_002920157.1 PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues YP_002920158.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3490 YP_002920159.1 internal ID: KP3492 YP_002920160.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis YP_002920161.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate YP_002920162.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_002920163.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_002920164.1 identified by Glimmer2; internal ID: KP3497 YP_002920165.1 Represses the expression of the zwf, eda, glp and gap YP_002920166.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_002920167.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA YP_002920168.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3501 YP_002920169.1 involved in transport of zinc(II) with ZnuA and C YP_002920170.1 involved in transport of zinc(II) with ZnuA and C YP_002920171.1 involved in transport of zinc(II) with ZnuA and C YP_002920172.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_002920173.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_002920174.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_002920175.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3508 YP_002920176.1 converts dATP to dAMP and pyrophosphate YP_002920177.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_002920178.1 internal ID: KP3511 YP_002920179.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3512 YP_002920180.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3513 YP_002920181.1 internal ID: KP3515 YP_002920182.1 internal ID: KP3516 YP_002920183.1 internal ID: KP3517 YP_002920184.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3518 YP_002920185.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_002920186.1 internal ID: KP3520 YP_002920187.1 internal ID: KP3521 YP_002920188.1 ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress YP_002920189.1 internal ID: KP3523 YP_002920190.1 biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature YP_002920191.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_002920192.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_002920193.1 internal ID: KP3527 YP_002920194.1 internal ID: KP3528 YP_002920195.1 internal ID: KP3530 YP_002920196.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3531 YP_002920197.1 internal ID: KP3532 YP_002920198.1 internal ID: KP3533 YP_002920199.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3534 YP_002920200.1 cytoplasmic iron storage protein YP_002920201.1 identified by GeneMark.hmm; internal ID: KP3536 YP_002920202.1 internal ID: KP3537 YP_002920203.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3538 YP_002920204.1 internal ID: KP3539 YP_002920205.1 internal ID: KP3540 YP_002920206.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_002920207.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system YP_002920208.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3543 YP_002920209.1 regulates genes involved in cell division YP_002920210.1 internal ID: KP3545 YP_002920211.1 internal ID: KP3547 YP_002920212.1 catalyzes the formation of pyruvate from D-cysteine YP_002920213.1 internal ID: KP3549 YP_002920214.1 converts 1,4-alpha-D-glucans to maltodextrin YP_002920215.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3551 YP_002920216.1 internal ID: KP3552 YP_002920217.1 identified by GeneMark and GeneMark.hmm; internal ID: KP3553 YP_002920218.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3554 YP_002920219.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3555 YP_002920220.1 internal ID: KP3557 YP_002920221.1 internal ID: KP3558 YP_002920222.1 internal ID: KP3559 YP_002920223.1 internal ID: KP3560 YP_002920224.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3561 YP_002920225.1 internal ID: KP3562 YP_002920226.1 internal ID: KP3563 YP_002920227.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3564 YP_002920228.1 internal ID: KP3565 YP_002920229.1 internal ID: KP3566 YP_002920230.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3567 YP_002920231.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3568 YP_002920232.1 LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB YP_002920233.1 Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation YP_002920234.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile YP_002920235.1 internal ID: KP3573 YP_002920236.1 internal ID: KP3574 YP_002920237.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3575 YP_002920238.1 internal ID: KP3576 YP_002920239.1 internal ID: KP3577 YP_002920240.1 internal ID: KP3578 YP_002920241.1 internal ID: KP3579 YP_002920242.1 internal ID: KP3581 YP_002920243.1 catalyzes the conversion of chorismate to salicylate in the biosynthesis of the siderophore yersiniabactin YP_002920244.1 internal ID: KP3584 YP_002920245.1 internal ID: KP3585 YP_002920246.1 internal ID: KP3586 YP_002920247.1 internal ID: KP3587 YP_002920248.1 internal ID: KP3588 YP_002920249.1 internal ID: KP3589 YP_002920250.1 internal ID: KP3590 YP_002920251.1 internal ID: KP3591 YP_002920252.1 internal ID: KP3592 YP_002920253.1 internal ID: KP3593 YP_002920254.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3595 YP_002920255.1 internal ID: KP3596 YP_002920256.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3597 YP_002920257.1 identified by Glimmer2; internal ID: KP3599 YP_002920258.1 internal ID: KP3600 YP_002920259.1 internal ID: KP3601 YP_002920260.1 internal ID: KP3602 YP_002920261.1 internal ID: KP3603 YP_002920262.1 identified by GeneMark.hmm; internal ID: KP3604 YP_002920263.1 internal ID: KP3605 YP_002920264.1 internal ID: KP3606 YP_002920265.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3607 YP_002920266.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space YP_002920267.1 internal ID: KP3611 YP_002920268.1 internal ID: KP3612 YP_002920269.1 internal ID: KP3613 YP_002920270.1 internal ID: KP3615 YP_002920271.1 identified by GeneMark.hmm; internal ID: KP3616 YP_002920272.1 identified by Glimmer2; internal ID: KP3617 YP_002920273.1 internal ID: KP3619 YP_002920274.1 identified by Glimmer2; internal ID: KP3620 YP_002920275.1 identified by GeneMark.hmm; internal ID: KP3621 YP_002920276.1 internal ID: KP3623 YP_002920277.1 internal ID: KP3624 YP_002920278.1 internal ID: KP3625 YP_002920279.1 internal ID: KP3626 YP_002920280.1 internal ID: KP3627 YP_002920281.1 internal ID: KP3628 YP_002920282.1 internal ID: KP3629 YP_002920283.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3630 YP_002920284.1 internal ID: KP3631 YP_002920285.1 internal ID: KP3633 YP_002920286.1 internal ID: KP3634 YP_002920287.1 internal ID: KP3635 YP_002920288.1 internal ID: KP3636 YP_002920289.1 identified by GeneMark.hmm; internal ID: KP3637 YP_002920290.1 identified by Glimmer2; internal ID: KP3638 YP_002920291.1 internal ID: KP3639 YP_002920292.1 identified by Glimmer2; internal ID: KP3640 YP_002920293.1 internal ID: KP3641 YP_002920294.1 internal ID: KP3642 YP_002920295.1 internal ID: KP3643 YP_002920296.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3644 YP_002920297.1 identified by GeneMark.hmm; internal ID: KP3645 YP_002920298.1 internal ID: KP3646 YP_002920299.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3647 YP_002920300.1 identified by GeneMark.hmm; internal ID: KP3648 YP_002920301.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3649 YP_002920302.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3650 YP_002920303.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3651 YP_002920304.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3652 YP_002920305.1 internal ID: KP3653 YP_002920306.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3654 YP_002920307.1 internal ID: KP3655 YP_002920308.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3656 YP_002920309.1 internal ID: KP3657 YP_002920310.1 identified by Glimmer2; internal ID: KP3658 YP_002920311.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3659 YP_002920312.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3660 YP_002920313.1 internal ID: KP3661 YP_002920314.1 internal ID: KP3662 YP_002920315.1 internal ID: KP3663 YP_002920316.1 internal ID: KP3664 YP_002920317.1 internal ID: KP3665 YP_002920318.1 internal ID: KP3666 YP_002920319.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole YP_002920320.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole YP_002920321.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3669 YP_002920322.1 internal ID: KP3670 YP_002920323.1 internal ID: KP3671 YP_002920324.1 removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains YP_002920325.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates YP_002920326.1 internal ID: KP3674 YP_002920327.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3675 YP_002920328.1 internal ID: KP3676 YP_002920329.1 internal ID: KP3677 YP_002920330.1 internal ID: KP3678 YP_002920331.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors YP_002920332.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_002920333.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_002920334.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate YP_002920335.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_002920336.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_002920337.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_002920338.1 internal ID: KP3687 YP_002920339.1 identified by GeneMark.hmm; internal ID: KP3688 YP_002920340.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3689 YP_002920341.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3690 YP_002920342.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3691 YP_002920343.1 internal ID: KP3693 YP_002920344.1 internal ID: KP3694 YP_002920345.1 internal ID: KP3695 YP_002920346.1 internal ID: KP3696 YP_002920347.1 internal ID: KP3697 YP_002920348.1 internal ID: KP3698 YP_002920349.1 internal ID: KP3699 YP_002920350.1 internal ID: KP3701 YP_002920351.1 internal ID: KP3702 YP_002920352.1 internal ID: KP3703 YP_002920353.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_002920354.1 WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid YP_002920355.1 internal ID: KP3706 YP_002920356.1 internal ID: KP3708 YP_002920357.1 internal ID: KP3709 YP_002920358.1 internal ID: KP3711 YP_002920359.1 internal ID: KP3712 YP_002920360.1 internal ID: KP3713 YP_002920361.1 internal ID: KP3714 YP_002920362.1 internal ID: KP3715 YP_002920363.1 internal ID: KP3716 YP_002920364.1 internal ID: KP3718 YP_002920365.1 internal ID: KP3719 YP_002920366.1 internal ID: KP3720 YP_002920367.1 internal ID: KP3721 YP_002920368.1 internal ID: KP3725 YP_002920369.1 together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose YP_002920370.1 internal ID: KP3727 YP_002920371.1 YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs YP_002920372.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_002920373.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_002920374.1 inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine YP_002920375.1 internal ID: KP3733 YP_002920376.1 internal ID: KP3735 YP_002920377.1 internal ID: KP3736 YP_002920378.1 identified by Glimmer2; internal ID: KP3738 YP_002920379.1 internal ID: KP3739 YP_002920380.1 internal ID: KP3740 YP_002920381.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate YP_002920382.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate YP_002920383.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate YP_002920384.1 internal ID: KP3745 YP_002920385.1 internal ID: KP3746 YP_002920386.1 response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport YP_002920387.1 internal ID: KP3748 YP_002920388.1 cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role YP_002920389.1 identified by Glimmer2; internal ID: KP3750 YP_002920390.1 internal ID: KP3751 YP_002920391.1 internal ID: KP3752 YP_002920392.1 internal ID: KP3753 YP_002920393.1 internal ID: KP3754 YP_002920394.1 internal ID: KP3755 YP_002920395.1 internal ID: KP3756 YP_002920396.1 internal ID: KP3757 YP_002920397.1 internal ID: KP3758 YP_002920398.1 internal ID: KP3759 YP_002920399.1 internal ID: KP3760 YP_002920400.1 internal ID: KP3761 YP_002920401.1 internal ID: KP3762 YP_002920402.1 internal ID: KP3763 YP_002920403.1 internal ID: KP3764 YP_002920404.1 internal ID: KP3765 YP_002920405.1 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate YP_002920406.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_002920407.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP YP_002920408.1 internal ID: KP3770 YP_002920409.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3771 YP_002920410.1 internal ID: KP3772 YP_002920411.1 internal ID: KP3773 YP_002920412.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3774 YP_002920413.1 internal ID: KP3775 YP_002920414.1 internal ID: KP3776 YP_002920415.1 internal ID: KP3777 YP_002920416.1 internal ID: KP3778 YP_002920417.1 internal ID: KP3779 YP_002920418.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3780 YP_002920419.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3781 YP_002920420.1 internal ID: KP3782 YP_002920421.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_002920422.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3784 YP_002920423.1 unknown function; when overproduced it confers drug-resistance YP_002920424.1 internal ID: KP3787 YP_002920425.1 internal ID: KP3790 YP_002920426.1 internal ID: KP3791 YP_002920427.1 internal ID: KP3793 YP_002920428.1 internal ID: KP3794 YP_002920429.1 internal ID: KP3795 YP_002920430.1 component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent YP_002920431.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3797 YP_002920432.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7 YP_002920433.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3799 YP_002920434.1 internal ID: KP3800 YP_002920435.1 may be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride YP_002920436.1 identified by Glimmer2; internal ID: KP3802 YP_002920437.1 internal ID: KP3803 YP_002920438.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002920439.1 identified by Glimmer2; internal ID: KP3805 YP_002920440.1 internal ID: KP3806 YP_002920441.1 internal ID: KP3807 YP_002920442.1 internal ID: KP3808 YP_002920443.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3809 YP_002920444.1 internal ID: KP3810 YP_002920445.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_002920446.1 internal ID: KP3812 YP_002920447.1 ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex YP_002920448.1 with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains YP_002920449.1 internal ID: KP3815 YP_002920450.1 negative regulator of the mglBAC operon for galactose utilization YP_002920451.1 internal ID: KP3817 YP_002920452.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_002920453.1 internal ID: KP3819 YP_002920454.1 Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein YP_002920455.1 internal ID: KP3821 YP_002920456.1 internal ID: KP3822 YP_002920457.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3823 YP_002920458.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues YP_002920459.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002920460.1 converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers YP_002920461.1 phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr YP_002920462.1 internal ID: KP3830 YP_002920463.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3831 YP_002920464.1 Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein YP_002920465.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate YP_002920466.1 internal ID: KP3834 YP_002920467.1 internal ID: KP3835 YP_002920468.1 internal ID: KP3836 YP_002920469.1 identified by Glimmer2; internal ID: KP3837 YP_002920470.1 by similarity, Spr seems to have peptidase activity; involved in thermoresistance YP_002920471.1 internal ID: KP3839 YP_002920472.1 internal ID: KP3840 YP_002920473.1 internal ID: KP3841 YP_002920474.1 internal ID: KP3842 YP_002920475.1 internal ID: KP3843 YP_002920476.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3844 YP_002920477.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance YP_002920479.1 catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA YP_002920480.1 internal ID: KP3848 YP_002920481.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_002920482.1 internal ID: KP3850 YP_002920483.1 internal ID: KP3851 YP_002920484.1 internal ID: KP3852 YP_002920485.1 internal ID: KP3853 YP_002920486.1 internal ID: KP3854 YP_002920487.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3855 YP_002920488.1 internal ID: KP3856 YP_002920489.1 internal ID: KP3857 YP_002920490.1 serine protease inhibitor, inhibits trypsin and other proteases YP_002920491.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate YP_002920492.1 internal ID: KP3862 YP_002920493.1 internal ID: KP3863 YP_002920494.1 efflux pump for the antibacterial peptide microcin J25 YP_002920495.1 internal ID: KP3866 YP_002920496.1 internal ID: KP3867 YP_002920497.1 catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway YP_002920498.1 allows for ions and hydrophilic solutes to cross the outer membrane YP_002920499.1 identified by Glimmer2; internal ID: KP3870 YP_002920500.1 internal ID: KP3871 YP_002920501.1 two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF YP_002920502.1 internal ID: KP3873 YP_002920503.1 negatively supercoils closed circular double-stranded DNA YP_002920504.1 Involved in ubiquinone biosynthesis YP_002920505.1 Catalyzes the rate-limiting step in dNTP synthesis YP_002920506.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA YP_002920507.1 plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases YP_002920508.1 hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic YP_002920509.1 catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell YP_002920510.1 anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor YP_002920511.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters YP_002920512.1 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate YP_002920513.1 internal ID: KP3885 YP_002920514.1 internal ID: KP3886 YP_002920515.1 internal ID: KP3887 YP_002920516.1 internal ID: KP3888 YP_002920517.1 internal ID: KP3889 YP_002920518.1 internal ID: KP3890 YP_002920519.1 internal ID: KP3894 YP_002920520.1 internal ID: KP3895 YP_002920521.1 internal ID: KP3898 YP_002920522.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate YP_002920523.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA YP_002920524.1 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA YP_002920525.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis YP_002920526.1 internal ID: KP3904 YP_002920527.1 internal ID: KP3906 YP_002920528.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions YP_002920529.1 Catalyzes the transfer of electrons from NADH to quinone YP_002920530.1 Catalyzes the transfer of electrons from NADH to quinone YP_002920531.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_002920532.1 Catalyzes the transfer of electrons from NADH to quinone YP_002920533.1 Catalyzes the transfer of electrons from NADH to quinone YP_002920534.1 Catalyzes the transfer of electrons from NADH to quinone YP_002920535.1 Catalyzes the transfer of electrons from NADH to quinone YP_002920536.1 Catalyzes the transfer of electrons from NADH to quinone YP_002920537.1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase YP_002920538.1 Catalyzes the transfer of electrons from NADH to quinone YP_002920539.1 NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms YP_002920540.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_002920541.1 Catalyzes the transfer of electrons from NADH to quinone YP_002920542.1 identified by Glimmer2; internal ID: KP3923 YP_002920543.1 internal ID: KP3924 YP_002920544.1 identified by Glimmer2; internal ID: KP3925 YP_002920545.1 identified by Glimmer2; internal ID: KP3926 YP_002920546.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor YP_002920547.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3928 YP_002920548.1 internal ID: KP3929 YP_002920549.1 internal ID: KP3930 YP_002920550.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3931 YP_002920551.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3932 YP_002920552.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_002920553.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate YP_002920554.1 internal ID: KP3935 YP_002920555.1 internal ID: KP3936 YP_002920556.1 internal ID: KP3937 YP_002920557.1 internal ID: KP3938 YP_002920558.1 catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate YP_002920559.1 internal ID: KP3940 YP_002920560.1 internal ID: KP3941 YP_002920561.1 internal ID: KP3942 YP_002920562.1 internal ID: KP3943 YP_002920563.1 internal ID: KP3944 YP_002920564.1 internal ID: KP3945 YP_002920565.1 internal ID: KP3946 YP_002920566.1 identified by Glimmer2; internal ID: KP3947 YP_002920567.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate YP_002920568.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_002920569.1 membrane protein required for colicin V production YP_002920570.1 internal ID: KP3952 YP_002920571.1 internal ID: KP3953 YP_002920572.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_002920573.1 internal ID: KP3956 YP_002920574.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_002920575.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3958 YP_002920576.1 internal ID: KP3959 YP_002920577.1 identified by GeneMark.hmm; internal ID: KP3960 YP_002920578.1 in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein YP_002920579.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3962 YP_002920580.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_002920581.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules YP_002920582.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3965 YP_002920583.1 internal ID: KP3966 YP_002920584.1 internal ID: KP3967 YP_002920585.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm YP_002920586.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_002920587.1 involved in methylation of ribosomal protein L3 YP_002920588.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3971 YP_002920589.1 internal ID: KP3972 YP_002920590.1 multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate YP_002920591.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth YP_002920592.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3975 YP_002920593.1 internal ID: KP3976 YP_002920594.1 internal ID: KP3977 YP_002920595.1 internal ID: KP3978 YP_002920596.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3979 YP_002920597.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3981 YP_002920598.1 controls the expression of the cynTSX operon involved in degrading and using cyanate as a sole nitrogen source YP_002920599.1 internal ID: KP3983 YP_002920600.1 MFS transporter family member induced in the presence of cyanate as part of a 3 gene operon; not essential YP_002920601.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3985 YP_002920602.1 identified by Glimmer2; internal ID: KP3986 YP_002920603.1 internal ID: KP3987 YP_002920604.1 internal ID: KP3988 YP_002920605.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate YP_002920606.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3991 YP_002920607.1 internal ID: KP3993 YP_002920608.1 internal ID: KP3994 YP_002920609.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP3995 YP_002920610.1 internal ID: KP3996 YP_002920611.1 internal ID: KP3997 YP_002920612.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP3998 YP_002920613.1 internal ID: KP3999 YP_002920614.1 internal ID: KP4000 YP_002920615.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_002920616.1 internal ID: KP4002 YP_002920617.1 internal ID: KP4003 YP_002920618.1 internal ID: KP4004 YP_002920619.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB YP_002920620.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure YP_002920621.1 putative role in sulfur assimilation YP_002920622.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis YP_002920623.1 internal ID: KP4009 YP_002920624.1 Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system YP_002920625.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose YP_002920626.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4013 YP_002920627.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal YP_002920628.1 internal ID: KP4015 YP_002920629.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4016 YP_002920630.1 catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide YP_002920631.1 internal ID: KP4018 YP_002920632.1 Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import YP_002920633.1 internal ID: KP4020 YP_002920634.1 internal ID: KP4021 YP_002920635.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4022 YP_002920636.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4023 YP_002920637.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4024 YP_002920638.1 internal ID: KP4026 YP_002920639.1 identified by Glimmer2; internal ID: KP4027 YP_002920640.1 internal ID: KP4028 YP_002920641.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_002920642.1 activates the transcription of the ethanolamine utilization operon YP_002920643.1 internal ID: KP4031 YP_002920644.1 internal ID: KP4032 YP_002920645.1 catalyzes the formation of acetaldehyde from ethanolamine YP_002920646.1 internal ID: KP4034 YP_002920647.1 ethanolamine utilization protein EutA YP_002920648.1 internal ID: KP4036 YP_002920649.1 internal ID: KP4037 YP_002920650.1 internal ID: KP4038 YP_002920651.1 internal ID: KP4039 YP_002920652.1 internal ID: KP4040 YP_002920653.1 internal ID: KP4041 YP_002920654.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta YP_002920655.1 internal ID: KP4043 YP_002920656.1 internal ID: KP4044 YP_002920657.1 internal ID: KP4046 YP_002920658.1 internal ID: KP4047 YP_002920659.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate YP_002920660.1 internal ID: KP4049 YP_002920661.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_002920662.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4051 YP_002920663.1 internal ID: KP4052 YP_002920664.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic) YP_002920665.1 internal ID: KP4054 YP_002920666.1 internal ID: KP4055 YP_002920667.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_002920668.1 internal ID: KP4057 YP_002920669.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate YP_002920670.1 internal ID: KP4059 YP_002920671.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4060 YP_002920672.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_002920673.1 internal ID: KP4062 YP_002920674.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_002920675.1 negative transcriptional regulator of the gcvTHP operon YP_002920676.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine YP_002920677.1 internal ID: KP4066 YP_002920678.1 identified by Glimmer2; internal ID: KP4067 YP_002920679.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4068 YP_002920680.1 internal ID: KP4069 YP_002920681.1 internal ID: KP4070 YP_002920682.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP YP_002920683.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4072 YP_002920684.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_002920685.1 converts 6-phospho-beta-D-glucosyl-(1,4)-D-glucose to glucose and glucose 6-phosphate; required for cellobiose uptake and metabolism YP_002920686.1 internal ID: KP4075 YP_002920687.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_002920688.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_002920689.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_002920690.1 internal ID: KP4079 YP_002920691.1 internal ID: KP4080 YP_002920692.1 internal ID: KP4081 YP_002920693.1 internal ID: KP4082 YP_002920694.1 internal ID: KP4083 YP_002920695.1 internal ID: KP4084 YP_002920696.1 internal ID: KP4085 YP_002920697.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_002920698.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_002920699.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_002920700.1 identified by Glimmer2 and GeneMark; internal ID: KP4089 YP_002920701.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4090 YP_002920702.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_002920703.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis YP_002920704.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4093 YP_002920705.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_002920706.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_002920707.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4096 YP_002920708.1 identified by Glimmer2; internal ID: KP4097 YP_002920709.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_002920710.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_002920711.1 penicillin-insensitive transglycosylase/transpeptidase YP_002920712.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4102 YP_002920713.1 catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds YP_002920714.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4104 YP_002920715.1 enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I YP_002920716.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide YP_002920717.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4108 YP_002920718.1 internal ID: KP4109 YP_002920719.1 involved in the maturation of iron-sulfur cluster-containing proteins YP_002920720.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins YP_002920721.1 forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein YP_002920722.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4113 YP_002920723.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis YP_002920724.1 regulates the expression of the iscRSUA operon YP_002920725.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4116 YP_002920726.1 internal ID: KP4117 YP_002920727.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4118 YP_002920728.1 internal ID: KP4119 YP_002920729.1 internal ID: KP4120 YP_002920730.1 internal ID: KP4121 YP_002920731.1 putative transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters YP_002920732.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4123 YP_002920733.1 internal ID: KP4124 YP_002920734.1 internal ID: KP4125 YP_002920735.1 internal ID: KP4127 YP_002920736.1 internal ID: KP4128 YP_002920737.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4129 YP_002920738.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_002920739.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine YP_002920740.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA YP_002920741.1 internal ID: KP4133 YP_002920742.1 internal ID: KP4134 YP_002920743.1 internal ID: KP4135 YP_002920744.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_002920745.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function YP_002920746.1 internal ID: KP4138 YP_002920747.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4139 YP_002920748.1 internal ID: KP4140 YP_002920749.1 internal ID: KP4141 YP_002920750.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_002920751.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_002920752.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_002920753.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_002920754.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_002920755.1 catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins YP_002920756.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_002920757.1 involved in the reduction of the SoxR iron-sulfur cluster YP_002920758.1 periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP YP_002920759.1 internal ID: KP4153 YP_002920760.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response YP_002920761.1 catalyzes the formation of oxaloacetate from L-aspartate YP_002920762.1 internal ID: KP4157 YP_002920763.1 facilitates an early step in the assembly of the 50S subunit of the ribosome YP_002920764.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit YP_002920765.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_002920766.1 internal ID: KP4161 YP_002920767.1 internal ID: KP4162 YP_002920768.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4163 YP_002920769.1 internal ID: KP4164 YP_002920770.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome YP_002920771.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4166 YP_002920772.1 internal ID: KP4167 YP_002920773.1 identified by Glimmer2; internal ID: KP4168 YP_002920774.1 internal ID: KP4170 YP_002920775.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4171 YP_002920776.1 responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA YP_002920777.1 with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline YP_002920778.1 associated with 30S ribosomal subunit; interferes with translation elongation YP_002920779.1 catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis YP_002920780.1 internal ID: KP4176 YP_002920781.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis YP_002920782.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive YP_002920783.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4179 YP_002920784.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4180 YP_002920785.1 internal ID: KP4181 YP_002920786.1 internal ID: KP4182 YP_002920787.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4183 YP_002920788.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_002920789.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_002920790.1 Essential for efficient processing of 16S rRNA YP_002920791.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_002920792.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins YP_002920793.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4190 YP_002920794.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4191 YP_002920795.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_002920796.1 catalyzes the phosphorylation of NAD to NADP YP_002920797.1 internal ID: KP4194 YP_002920798.1 internal ID: KP4195 YP_002920799.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4196 YP_002920800.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4197 YP_002920801.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_002920802.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4199 YP_002920803.1 internal ID: KP4200 YP_002920804.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4201 YP_002920805.1 internal ID: KP4202 YP_002920806.1 internal ID: KP4204 YP_002920807.1 internal ID: KP4205 YP_002920808.1 internal ID: KP4206 YP_002920809.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4207 YP_002920810.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4208 YP_002920811.1 internal ID: KP4209 YP_002920812.1 internal ID: KP4210 YP_002920813.1 internal ID: KP4211 YP_002920814.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4213 YP_002920815.1 identified by Glimmer2; internal ID: KP4215 YP_002920816.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4216 YP_002920817.1 internal ID: KP4217 YP_002920818.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4218 YP_002920819.1 internal ID: KP4219 YP_002920820.1 internal ID: KP4220 YP_002920821.1 internal ID: KP4221 YP_002920822.1 internal ID: KP4222 YP_002920823.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4224 YP_002920824.1 internal ID: KP4225 YP_002920825.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4226 YP_002920826.1 internal ID: KP4227 YP_002920827.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4228 YP_002920828.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4229 YP_002920829.1 internal ID: KP4231 YP_002920830.1 internal ID: KP4232 YP_002920831.1 internal ID: KP4233 YP_002920832.1 internal ID: KP4235 YP_002920833.1 internal ID: KP4236 YP_002920834.1 internal ID: KP4237 YP_002920835.1 internal ID: KP4238 YP_002920836.1 internal ID: KP4239 YP_002920837.1 internal ID: KP4240 YP_002920838.1 internal ID: KP4241 YP_002920839.1 internal ID: KP4242 YP_002920840.1 internal ID: KP4243 YP_002920841.1 internal ID: KP4244 YP_002920842.1 internal ID: KP4245 YP_002920843.1 internal ID: KP4246 YP_002920844.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4247 YP_002920845.1 internal ID: KP4248 YP_002920846.1 internal ID: KP4249 YP_002920847.1 internal ID: KP4250 YP_002920848.1 internal ID: KP4251 YP_002920849.1 internal ID: KP4252 YP_002920850.1 internal ID: KP4253 YP_002920851.1 internal ID: KP4254 YP_002920852.1 internal ID: KP4255 YP_002920853.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4256 YP_002920854.1 internal ID: KP4257 YP_002920855.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4258 YP_002920856.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4259 YP_002920857.1 internal ID: KP4260 YP_002920858.1 identified by Glimmer2; internal ID: KP4261 YP_002920859.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4262 YP_002920860.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4263 YP_002920861.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4264 YP_002920862.1 internal ID: KP4265 YP_002920863.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4266 YP_002920864.1 internal ID: KP4267 YP_002920865.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF YP_002920866.1 Catalyzes the rate-limiting step in dNTP synthesis YP_002920867.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE YP_002920868.1 internal ID: KP4271 YP_002920869.1 with ProVX is involved in the high-affinity uptake of glycine betaine YP_002920870.1 with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine YP_002920871.1 internal ID: KP4274 YP_002920872.1 internal ID: KP4275 YP_002920873.1 DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB YP_002920874.1 internal ID: KP4279 YP_002920875.1 internal ID: KP4280 YP_002920876.1 internal ID: KP4281 YP_002920877.1 internal ID: KP4282 YP_002920878.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_002920879.1 involved in the first step of glutathione biosynthesis YP_002920880.1 internal ID: KP4286 YP_002920881.1 YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent YP_002920882.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4288 YP_002920883.1 affects carbohydrate metabolism; has regulatory role in many processes YP_002920884.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002920885.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities YP_002920886.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_002920887.1 internal ID: KP4295 YP_002920888.1 internal ID: KP4296 YP_002920889.1 internal ID: KP4297 YP_002920890.1 internal ID: KP4298 YP_002920891.1 membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan YP_002920892.1 internal ID: KP4300 YP_002920893.1 internal ID: KP4301 YP_002920894.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002920895.1 catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate YP_002920896.1 regulator for glucitol utilization YP_002920897.1 regulates genes involved in glucitol utilization YP_002920898.1 catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate YP_002920899.1 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon YP_002920900.1 identified by Glimmer2; internal ID: KP4310 YP_002920901.1 detoxifies nitric oxide using NADH YP_002920902.1 catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase YP_002920903.1 internal ID: KP4313 YP_002920904.1 internal ID: KP4314 YP_002920905.1 involved in electron transport from formate to hydrogen YP_002920906.1 internal ID: KP4316 YP_002920907.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002920908.1 internal ID: KP4318 YP_002920909.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4319 YP_002920910.1 involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE YP_002920911.1 internal ID: KP4321 YP_002920912.1 internal ID: KP4322 YP_002920913.1 electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate YP_002920914.1 internal ID: KP4325 YP_002920915.1 internal ID: KP4326 YP_002920916.1 catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3) YP_002920917.1 internal ID: KP4328 YP_002920918.1 regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon YP_002920919.1 plays a role in hydrogenase nickel cofactor insertion YP_002920920.1 GTP hydrolase involved in nickel liganding into hydrogenases YP_002920921.1 HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase YP_002920922.1 internal ID: KP4334 YP_002920923.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4335 YP_002920924.1 internal ID: KP4336 YP_002920925.1 internal ID: KP4337 YP_002920926.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4338 YP_002920927.1 internal ID: KP4339 YP_002920928.1 internal ID: KP4340 YP_002920929.1 internal ID: KP4342 YP_002920930.1 internal ID: KP4343 YP_002920931.1 internal ID: KP4344 YP_002920932.1 internal ID: KP4345 YP_002920933.1 internal ID: KP4346 YP_002920934.1 internal ID: KP4347 YP_002920935.1 internal ID: KP4348 YP_002920936.1 internal ID: KP4349 YP_002920937.1 internal ID: KP4350 YP_002920938.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4351 YP_002920939.1 internal ID: KP4352 YP_002920940.1 internal ID: KP4353 YP_002920941.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_002920942.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4355 YP_002920943.1 internal ID: KP4356 YP_002920944.1 internal ID: KP4358 YP_002920945.1 internal ID: KP4359 YP_002920946.1 internal ID: KP4361 YP_002920947.1 with HmuTU is involved in the transport of hemin YP_002920948.1 This protein performs the mismatch recognition step during the DNA repair process YP_002920949.1 internal ID: KP4364 YP_002920950.1 internal ID: KP4365 YP_002920951.1 internal ID: KP4367 YP_002920952.1 internal ID: KP4368 YP_002920953.1 internal ID: KP4369 YP_002920954.1 internal ID: KP4370 YP_002920955.1 internal ID: KP4371 YP_002920956.1 internal ID: KP4372 YP_002920957.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses YP_002920958.1 outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus YP_002920959.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins YP_002920960.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_002920961.1 catalyzes the modification of U13 in tRNA(Glu) YP_002920962.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_002920963.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_002920964.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein YP_002920965.1 internal ID: KP4381 YP_002920966.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis YP_002920967.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ YP_002920968.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_002920969.1 internal ID: KP4385 YP_002920970.1 catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3 YP_002920971.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite YP_002920972.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide YP_002920973.1 catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity YP_002920974.1 internal ID: KP4390 YP_002920975.1 internal ID: KP4391 YP_002920976.1 identified by Glimmer2; internal ID: KP4392 YP_002920977.1 internal ID: KP4393 YP_002920978.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_002920979.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_002920980.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era YP_002920981.1 (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP YP_002920982.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S] YP_002920983.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system YP_002920984.1 internal ID: KP4401 YP_002920985.1 internal ID: KP4402 YP_002920986.1 internal ID: KP4403 YP_002920987.1 internal ID: KP4404 YP_002920988.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_002920989.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp YP_002920990.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4407 YP_002920991.1 putative SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function YP_002920992.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis YP_002920993.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4410 YP_002920994.1 internal ID: KP4414 YP_002920995.1 internal ID: KP4416 YP_002920996.1 internal ID: KP4418 YP_002920997.1 internal ID: KP4419 YP_002920998.1 internal ID: KP4420 YP_002920999.1 internal ID: KP4421 YP_002921000.1 internal ID: KP4422 YP_002921001.1 internal ID: KP4423 YP_002921002.1 internal ID: KP4424 YP_002921003.1 internal ID: KP4425 YP_002921004.1 internal ID: KP4426 YP_002921005.1 internal ID: KP4428 YP_002921006.1 has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups YP_002921007.1 internal ID: KP4430 YP_002921008.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate YP_002921009.1 internal ID: KP4432 YP_002921010.1 catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose YP_002921011.1 internal ID: KP4434 YP_002921012.1 internal ID: KP4435 YP_002921013.1 regulates expression of genes involved in L-fucose utilization YP_002921014.1 internal ID: KP4437 YP_002921015.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4438 YP_002921016.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence YP_002921017.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4440 YP_002921018.1 internal ID: KP4441 YP_002921019.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4442 YP_002921020.1 internal ID: KP4444 YP_002921021.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues YP_002921022.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole YP_002921023.1 catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP YP_002921024.1 catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation YP_002921025.1 with CbiNQ forms the ABC transporter for cobalt import YP_002921026.1 internal ID: KP4451 YP_002921027.1 periplasmic cobalt binding component of the cobalt transport system YP_002921028.1 catalyzes the ATP-dependent transport of cobalt YP_002921029.1 catalyzes the formation of precorrin-3A from precorrin-2 YP_002921030.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4455 YP_002921031.1 CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6 YP_002921032.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4457 YP_002921033.1 catalyzes the formation of cobalt-precorrin 4 from cobalt-precorrin 3 YP_002921034.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4459 YP_002921035.1 catalyzes the methylation of either C-15 or C-5 in cobalt-precorrin-6Y to form cobalt-precorrin-7W; decarboxylating YP_002921036.1 catalyzes the methylation of C-5 in cobalt-precorrin-6Y to form cobalt-precorrin-7W-a YP_002921037.1 Catalyzes the methylation of C-1 in cobalt-precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A YP_002921038.1 catalyzes the interconversion of cobalt-precorrin-8X and cobyrinic acid in the anaerobic biosynthesis of cobalamin YP_002921039.1 CobD; CbiD in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group YP_002921040.1 responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid YP_002921041.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4467 YP_002921042.1 identified by Glimmer2; internal ID: KP4468 YP_002921043.1 internal ID: KP4469 YP_002921044.1 identified by Glimmer2; internal ID: KP4470 YP_002921045.1 internal ID: KP4471 YP_002921046.1 internal ID: KP4472 YP_002921047.1 internal ID: KP4473 YP_002921048.1 internal ID: KP4474 YP_002921049.1 internal ID: KP4475 YP_002921050.1 internal ID: KP4476 YP_002921051.1 internal ID: KP4477 YP_002921052.1 internal ID: KP4478 YP_002921053.1 internal ID: KP4479 YP_002921054.1 internal ID: KP4480 YP_002921055.1 internal ID: KP4481 YP_002921056.1 internal ID: KP4482 YP_002921057.1 internal ID: KP4483 YP_002921058.1 internal ID: KP4485 YP_002921059.1 internal ID: KP4486 YP_002921060.1 internal ID: KP4487 YP_002921061.1 internal ID: KP4488 YP_002921062.1 internal ID: KP4489 YP_002921063.1 internal ID: KP4490 YP_002921064.1 involved in coenzyme B(12)-dependent 1, 2-propanediol degradation; important for the synthesis of propionyl coenzyme A during growth on 1,2-propanediol YP_002921065.1 internal ID: KP4492 YP_002921066.1 cobalamin biosynthesis protein; decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin; structurally similar to histidinol phosphate aminotransferase YP_002921067.1 internal ID: KP4494 YP_002921068.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis YP_002921069.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4496 YP_002921070.1 helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity YP_002921071.1 helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity YP_002921072.1 internal ID: KP4499 YP_002921073.1 catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination YP_002921074.1 internal ID: KP4501 YP_002921075.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4502 YP_002921076.1 internal ID: KP4503 YP_002921077.1 internal ID: KP4504 YP_002921078.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_002921079.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_002921080.1 member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr YP_002921081.1 hydrolyzes diadenosine polyphosphate YP_002921082.1 identified by Glimmer2; internal ID: KP4510 YP_002921083.1 identified by Glimmer2; internal ID: KP4511 YP_002921084.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair YP_002921085.1 internal ID: KP4513 YP_002921086.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4514 YP_002921087.1 complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH YP_002921088.1 internal ID: KP4516 YP_002921089.1 Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1 YP_002921090.1 identified by Glimmer2; internal ID: KP4518 YP_002921091.1 controls transcription of galETKM YP_002921092.1 internal ID: KP4520 YP_002921093.1 internal ID: KP4521 YP_002921094.1 internal ID: KP4523 YP_002921095.1 internal ID: KP4524 YP_002921096.1 internal ID: KP4525 YP_002921097.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding YP_002921098.1 activates the transcription of the lysA gene encoding diaminopimelate decarboxylase YP_002921099.1 internal ID: KP4528 YP_002921102.1 internal ID: KP4531 YP_002921103.1 internal ID: KP4532 YP_002921104.1 internal ID: KP4533 YP_002921105.1 internal ID: KP4534 YP_002921106.1 internal ID: KP4535 YP_002921107.1 internal ID: KP4536 YP_002921108.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments YP_002921109.1 identified by Glimmer2; internal ID: KP4538 YP_002921110.1 internal ID: KP4539 YP_002921111.1 internal ID: KP4540 YP_002921112.1 catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate YP_002921113.1 identified by Glimmer2; internal ID: KP4542 YP_002921114.1 internal ID: KP4543 YP_002921115.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4544 YP_002921116.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis YP_002921117.1 internal ID: KP4546 YP_002921118.1 internal ID: KP4548 YP_002921119.1 internal ID: KP4549 YP_002921120.1 internal ID: KP4550 YP_002921121.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4551 YP_002921122.1 internal ID: KP4552 YP_002921123.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4554 YP_002921124.1 internal ID: KP4555 YP_002921125.1 internal ID: KP4557 YP_002921126.1 internal ID: KP4558 YP_002921127.1 internal ID: KP4560 YP_002921128.1 internal ID: KP4561 YP_002921129.1 identified by Glimmer2; internal ID: KP4562 YP_002921130.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4563 YP_002921131.1 internal ID: KP4564 YP_002921132.1 internal ID: KP4565 YP_002921133.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4566 YP_002921134.1 inversion of on/off regulator of fimA YP_002921135.1 inversion of on/off regulator of fimA YP_002921136.1 identified by Glimmer2; internal ID: KP4570 YP_002921137.1 internal ID: KP4571 YP_002921138.1 internal ID: KP4572 YP_002921139.1 internal ID: KP4573 YP_002921140.1 internal ID: KP4574 YP_002921141.1 internal ID: KP4575 YP_002921142.1 internal ID: KP4576 YP_002921143.1 internal ID: KP4577 YP_002921144.1 internal ID: KP4578 YP_002921145.1 internal ID: KP4580 YP_002921146.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4582 YP_002921147.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4583 YP_002921148.1 with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride YP_002921149.1 possibly part of a tripartite efflux system composed of MdtN, MdtO and MdtP which could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride YP_002921150.1 part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family YP_002921151.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4588 YP_002921152.1 internal ID: KP4589 YP_002921153.1 internal ID: KP4590 YP_002921154.1 internal ID: KP4591 YP_002921155.1 internal ID: KP4592 YP_002921156.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4593 YP_002921157.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4594 YP_002921158.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4595 YP_002921159.1 internal ID: KP4596 YP_002921160.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4597 YP_002921161.1 internal ID: KP4598 YP_002921162.1 internal ID: KP4599 YP_002921163.1 internal ID: KP4600 YP_002921164.1 internal ID: KP4601 YP_002921165.1 internal ID: KP4602 YP_002921166.1 internal ID: KP4603 YP_002921167.1 catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate YP_002921168.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_002921169.1 internal ID: KP4607 YP_002921170.1 5'-3' single-stranded-DNA-specific exonuclease YP_002921171.1 DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity YP_002921172.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_002921173.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic YP_002921174.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4612 YP_002921175.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4613 YP_002921176.1 physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator YP_002921177.1 internal ID: KP4615 YP_002921178.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4617 YP_002921179.1 internal ID: KP4618 YP_002921180.1 internal ID: KP4619 YP_002921181.1 internal ID: KP4620 YP_002921182.1 internal ID: KP4621 YP_002921183.1 internal ID: KP4622 YP_002921184.1 internal ID: KP4623 YP_002921185.1 internal ID: KP4624 YP_002921186.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_002921187.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_002921188.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_002921189.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4629 YP_002921190.1 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone YP_002921191.1 exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide YP_002921192.1 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown YP_002921193.1 identified by GeneMark.hmm; internal ID: KP4633 YP_002921194.1 ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms; unknown function YP_002921195.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_002921196.1 identified by Glimmer2; internal ID: KP4636 YP_002921197.1 internal ID: KP4637 YP_002921198.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_002921199.1 internal ID: KP4639 YP_002921200.1 Involved in the export of arginine YP_002921201.1 participates in the regulation of osmotic pressure changes within the cel YP_002921202.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate YP_002921203.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_002921204.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate YP_002921205.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_002921206.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4646 YP_002921207.1 internal ID: KP4647 YP_002921208.1 catalyzes the formation of putrescine from agmatine YP_002921209.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis YP_002921210.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_002921211.1 internal ID: KP4651 YP_002921212.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4652 YP_002921213.1 internal ID: KP4653 YP_002921214.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4654 YP_002921215.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_002921216.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4657 YP_002921217.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_002921218.1 activates the csgBA and csgDEFG operons involved in biofilm formation YP_002921219.1 internal ID: KP4660 YP_002921220.1 internal ID: KP4661 YP_002921221.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4662 YP_002921222.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4664 YP_002921223.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_002921224.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_002921225.1 internal ID: KP4667 YP_002921226.1 internal ID: KP4668 YP_002921227.1 internal ID: KP4669 YP_002921228.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4670 YP_002921229.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4671 YP_002921230.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_002921231.1 internal ID: KP4673 YP_002921232.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4674 YP_002921233.1 Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues YP_002921234.1 internal ID: KP4677 YP_002921235.1 internal ID: KP4678 YP_002921236.1 internal ID: KP4679 YP_002921237.1 identified by Glimmer2; internal ID: KP4680 YP_002921238.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4681 YP_002921239.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4682 YP_002921240.1 internal ID: KP4683 YP_002921241.1 internal ID: KP4684 YP_002921242.1 internal ID: KP4685 YP_002921243.1 internal ID: KP4686 YP_002921244.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4687 YP_002921245.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4688 YP_002921246.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4689 YP_002921247.1 internal ID: KP4690 YP_002921248.1 catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction YP_002921251.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4694 YP_002921252.1 YghU; B2989; one of eight putative glutathione transferase proteins from E. coli YP_002921253.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4696 YP_002921254.1 internal ID: KP4697 YP_002921255.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4699 YP_002921256.1 internal ID: KP4700 YP_002921257.1 internal ID: KP4701 YP_002921258.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell YP_002921259.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell YP_002921260.1 identified by Glimmer2; internal ID: KP4706 YP_002921261.1 catalyzes the formation of L-homocysteine from cystathionine YP_002921262.1 internal ID: KP4708 YP_002921263.1 internal ID: KP4709 YP_002921264.1 internal ID: KP4711 YP_002921265.1 methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate YP_002921266.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4713 YP_002921267.1 internal ID: KP4714 YP_002921268.1 internal ID: KP4715 YP_002921269.1 internal ID: KP4716 YP_002921270.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_002921271.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4718 YP_002921272.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4719 YP_002921273.1 response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes YP_002921274.1 internal ID: KP4721 YP_002921275.1 internal ID: KP4722 YP_002921276.1 internal ID: KP4723 YP_002921277.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4724 YP_002921278.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_002921279.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate YP_002921280.1 internal ID: KP4727 YP_002921281.1 internal ID: KP4728 YP_002921282.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_002921283.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell YP_002921284.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4731 YP_002921285.1 internal ID: KP4732 YP_002921287.1 seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine YP_002921288.1 internal ID: KP4735 YP_002921289.1 DHBP synthase; functions during riboflavin biosynthesis YP_002921290.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4738 YP_002921291.1 Involved in glycogen synthesis. May be involved in glycogen priming YP_002921292.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose YP_002921293.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme YP_002921294.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4744 YP_002921295.1 identified by Glimmer2; internal ID: KP4745 YP_002921296.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4746 YP_002921297.1 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases YP_002921298.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_002921299.1 catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin YP_002921300.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_002921303.1 internal ID: KP4753 YP_002921304.1 UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter YP_002921305.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem to be active YP_002921306.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits YP_002921307.1 involved in the assembly of the urease metallocenter; possible nickel donor YP_002921308.1 internal ID: KP4760 YP_002921309.1 internal ID: KP4761 YP_002921310.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4762 YP_002921311.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_002921312.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_002921313.1 synthesizes RNA primers at the replication forks YP_002921314.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria YP_002921315.1 internal ID: KP4767 YP_002921316.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4769 YP_002921317.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4770 YP_002921318.1 response regulator in two-component regulatory system with EvgS; phosphorylated EvgA activates ompC, emrKY, gadABC, hdeAB and others genes; involved in acid resistance, osmotic adaption, and drug resistance YP_002921319.1 internal ID: KP4773 YP_002921322.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4776 YP_002921323.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4777 YP_002921324.1 internal ID: KP4778 YP_002921325.1 internal ID: KP4779 YP_002921326.1 internal ID: KP4780 YP_002921327.1 internal ID: KP4781 YP_002921328.1 internal ID: KP4782 YP_002921329.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4783 YP_002921330.1 internal ID: KP4785 YP_002921331.1 internal ID: KP4786 YP_002921332.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4788 YP_002921333.1 Positively regulates the dhaKLM operon from a sigma-70 promoter YP_002921334.1 internal ID: KP4790 YP_002921335.1 identified by Glimmer2; internal ID: KP4791 YP_002921336.1 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase YP_002921337.1 with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone YP_002921338.1 phosphotransferaese subunit; phosphorylates dihydroxyacetone along with DhaK/DhaL YP_002921339.1 internal ID: KP4795 YP_002921340.1 internal ID: KP4796 YP_002921341.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4797 YP_002921342.1 catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate YP_002921343.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4799 YP_002921344.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4800 YP_002921345.1 internal ID: KP4801 YP_002921346.1 internal ID: KP4802 YP_002921347.1 internal ID: KP4803 YP_002921348.1 internal ID: KP4804 YP_002921349.1 identified by Glimmer2; internal ID: KP4805 YP_002921350.1 internal ID: KP4806 YP_002921351.1 internal ID: KP4807 YP_002921352.1 internal ID: KP4808 YP_002921353.1 internal ID: KP4809 YP_002921354.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4810 YP_002921355.1 internal ID: KP4811 YP_002921356.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4812 YP_002921357.1 internal ID: KP4813 YP_002921358.1 internal ID: KP4814 YP_002921359.1 involved in the import of serine and threonine coupled with the import of sodium YP_002921360.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4816 YP_002921361.1 internal ID: KP4817 YP_002921362.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism YP_002921363.1 internal ID: KP4819 YP_002921364.1 regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization. YP_002921365.1 internal ID: KP4821 YP_002921366.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4822 YP_002921367.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4823 YP_002921368.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4824 YP_002921369.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4825 YP_002921370.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4826 YP_002921371.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4827 YP_002921372.1 internal ID: KP4828 YP_002921373.1 internal ID: KP4830 YP_002921374.1 internal ID: KP4831 YP_002921375.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4832 YP_002921376.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4833 YP_002921377.1 internal ID: KP4835 YP_002921378.1 identified by Glimmer2; internal ID: KP4836 YP_002921379.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4837 YP_002921380.1 internal ID: KP4838 YP_002921381.1 catalyzes the reduction of tartronate semialdehyde to glycerate YP_002921382.1 cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate YP_002921383.1 internal ID: KP4842 YP_002921384.1 internal ID: KP4844 YP_002921385.1 internal ID: KP4845 YP_002921386.1 internal ID: KP4846 YP_002921387.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway YP_002921388.1 internal ID: KP4848 YP_002921389.1 internal ID: KP4849 YP_002921390.1 internal ID: KP4850 YP_002921391.1 internal ID: KP4851 YP_002921392.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002921393.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002921394.1 internal ID: KP4854 YP_002921395.1 Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate YP_002921396.1 internal ID: KP4856 YP_002921397.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4857 YP_002921398.1 internal ID: KP4858 YP_002921399.1 internal ID: KP4859 YP_002921400.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4861 YP_002921401.1 Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein YP_002921402.1 internal ID: KP4864 YP_002921403.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4865 YP_002921404.1 internal ID: KP4866 YP_002921405.1 internal ID: KP4867 YP_002921406.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4868 YP_002921407.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4869 YP_002921408.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4870 YP_002921409.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4871 YP_002921410.1 internal ID: KP4873 YP_002921411.1 internal ID: KP4874 YP_002921412.1 internal ID: KP4875 YP_002921413.1 tryptophan transporter of high affinity YP_002921414.1 participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division YP_002921415.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing YP_002921416.1 internal ID: KP4882 YP_002921417.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_002921418.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_002921419.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_002921420.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_002921421.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_002921422.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_002921423.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis YP_002921424.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4891 YP_002921425.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4892 YP_002921426.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4893 YP_002921427.1 internal ID: KP4894 YP_002921428.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_002921429.1 catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate YP_002921430.1 inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins YP_002921431.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit YP_002921432.1 RNA binding protein found associated to pre-50S subunit of the ribosome; putative role in ribosome assembly; necessary for optimal growth but not cell viability YP_002921433.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_002921434.1 penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains YP_002921435.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_002921436.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4903 YP_002921437.1 involved in the peptidyltransferase reaction during translation YP_002921438.1 internal ID: KP4907 YP_002921439.1 internal ID: KP4908 YP_002921440.1 internal ID: KP4909 YP_002921441.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_002921442.1 internal ID: KP4912 YP_002921443.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4913 YP_002921444.1 internal ID: KP4914 YP_002921445.1 internal ID: KP4915 YP_002921446.1 internal ID: KP4916 YP_002921447.1 ATP-binding subunit of a putative ABC toluene efflux transporter YP_002921448.1 YrbG; inner membrane protein involved in cell envelope integrity; putative sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers YP_002921449.1 internal ID: KP4919 YP_002921450.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis YP_002921451.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4921 YP_002921452.1 LptA; periplasmic binding protein part of a putative ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system YP_002921453.1 internal ID: KP4923 YP_002921454.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_002921455.1 YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing YP_002921456.1 internal ID: KP4926 YP_002921457.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4927 YP_002921458.1 internal ID: KP4928 YP_002921459.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan YP_002921460.1 internal ID: KP4930 YP_002921461.1 sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA YP_002921462.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate YP_002921463.1 internal ID: KP4933 YP_002921464.1 internal ID: KP4934 YP_002921465.1 internal ID: KP4935 YP_002921466.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate YP_002921467.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_002921468.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate YP_002921469.1 internal ID: KP4939 YP_002921470.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation YP_002921471.1 forms a direct contact with the tRNA during translation YP_002921472.1 internal ID: KP4943 YP_002921473.1 internal ID: KP4944 YP_002921474.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4945 YP_002921475.1 internal ID: KP4946 YP_002921476.1 internal ID: KP4947 YP_002921477.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4948 YP_002921478.1 internal ID: KP4950 YP_002921479.1 catalyzes the formation of pyruvate from oxaloacetate YP_002921480.1 catalyzes the decarboxylation of oxaloacetate to form pyruvate and carbon dioxide YP_002921481.1 Involved in the tartrate degradation pathway YP_002921482.1 Involved in the tartrate degradation pathway YP_002921483.1 internal ID: KP4956 YP_002921484.1 internal ID: KP4957 YP_002921485.1 internal ID: KP4959 YP_002921486.1 oxidizes malate to oxaloacetate YP_002921487.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes YP_002921488.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4962 YP_002921489.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4963 YP_002921490.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4964 YP_002921491.1 with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate YP_002921492.1 with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate YP_002921493.1 membrane protein AaeX; the gene is a member of the aaeXAB operon YP_002921494.1 internal ID: KP4968 YP_002921495.1 responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA YP_002921496.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4970 YP_002921497.1 involved in the processing of the 5'end of 16S rRNA YP_002921498.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_002921499.1 part of cell wall structural complex MreBCD; transmembrane component YP_002921500.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_002921501.1 functions in MreBCD complex in some organisms YP_002921502.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules YP_002921503.1 identified by Glimmer2; internal ID: KP4977 YP_002921504.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_002921505.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme YP_002921506.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_002921507.1 internal ID: KP4981 YP_002921508.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_002921509.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4984 YP_002921510.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase YP_002921511.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_002921512.1 identified by Glimmer2; internal ID: KP4987 YP_002921513.1 internal ID: KP4988 YP_002921514.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription YP_002921515.1 internal ID: KP4990 YP_002921516.1 internal ID: KP4991 YP_002921517.1 internal ID: KP4992 YP_002921518.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP4994 YP_002921519.1 identified by Glimmer2; internal ID: KP4995 YP_002921520.1 identified by Glimmer2; internal ID: KP4997 YP_002921521.1 internal ID: KP4998 YP_002921522.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP4999 YP_002921523.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_002921524.1 RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA YP_002921525.1 internal ID: KP5002 YP_002921526.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5003 YP_002921527.1 internal ID: KP5004 YP_002921528.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_002921529.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth YP_002921530.1 catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase YP_002921531.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_002921532.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock YP_002921533.1 internal ID: KP5010 YP_002921534.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators YP_002921535.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5012 YP_002921536.1 is a component of the macrolide binding site in the peptidyl transferase center YP_002921537.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_002921538.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_002921539.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_002921540.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_002921541.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_002921542.1 late assembly protein YP_002921543.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_002921544.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_002921545.1 binds 5S rRNA along with protein L5 and L25 YP_002921546.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_002921547.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_002921548.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_002921549.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_002921550.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_002921551.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_002921552.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_002921553.1 one of the stabilizing components for the large ribosomal subunit YP_002921554.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_002921555.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_002921556.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_002921557.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_002921558.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_002921559.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_002921560.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_002921561.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_002921562.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_002921563.1 internal ID: KP5046 YP_002921564.1 iron storage protein YP_002921565.1 internal ID: KP5048 YP_002921566.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_002921567.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_002921568.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_002921569.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_002921570.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_002921571.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_002921572.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_002921573.1 internal ID: KP5058 YP_002921574.1 rotamase YP_002921575.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5060 YP_002921576.1 rotamase YP_002921577.1 internal ID: KP5063 YP_002921578.1 involved in potassium efflux YP_002921579.1 required for KefB activity YP_002921580.1 internal ID: KP5066 YP_002921581.1 internal ID: KP5067 YP_002921582.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5068 YP_002921583.1 internal ID: KP5069 YP_002921584.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5070 YP_002921585.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons YP_002921586.1 internal ID: KP5072 YP_002921587.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate YP_002921588.1 aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity YP_002921589.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5075 YP_002921590.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP5076 YP_002921591.1 internal ID: KP5077 YP_002921592.1 internal ID: KP5079 YP_002921593.1 Catalyzes the deamination of cytosine to uracil and ammonia YP_002921594.1 internal ID: KP5082 YP_002921595.1 involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations YP_002921596.1 multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin YP_002921597.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002921598.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate YP_002921599.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate YP_002921600.1 internal ID: KP5088 YP_002921601.1 internal ID: KP5089 YP_002921602.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_002921603.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_002921604.1 outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa YP_002921605.1 identified by GeneMark.hmm; internal ID: KP5093 YP_002921606.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5094 YP_002921607.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5095 YP_002921608.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5096 YP_002921609.1 bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits YP_002921610.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_002921611.1 internal ID: KP5099 YP_002921612.1 internal ID: KP5100 YP_002921613.1 internal ID: KP5102 YP_002921614.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_002921615.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_002921616.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR YP_002921617.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation YP_002921618.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_002921619.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5108 YP_002921620.1 internal ID: KP5110 YP_002921621.1 cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake YP_002921622.1 internal ID: KP5112 YP_002921623.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP5113 YP_002921624.1 internal ID: KP5114 YP_002921625.1 internal ID: KP5115 YP_002921626.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source YP_002921627.1 internal ID: KP5119 YP_002921628.1 amylomaltase; acts to release glucose from maltodextrins YP_002921629.1 internal ID: KP5121 YP_002921630.1 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides YP_002921631.1 represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism YP_002921632.1 protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity YP_002921633.1 belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine YP_002921634.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane YP_002921635.1 internal ID: KP5127 YP_002921636.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose YP_002921637.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_002921638.1 catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen YP_002921639.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_002921640.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_002921641.1 identified by Glimmer2; internal ID: KP5133 YP_002921642.1 internal ID: KP5134 YP_002921643.1 thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate YP_002921644.1 internal ID: KP5136 YP_002921645.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5137 YP_002921646.1 internal ID: KP5138 YP_002921647.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5139 YP_002921648.1 YhhY; regulated by the fur regulator; unknown function YP_002921649.1 periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides YP_002921650.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5142 YP_002921651.1 hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate YP_002921652.1 part of the UgpABCE glycerol-3-phosphate uptake system YP_002921653.1 with UgpABC is involved in uptake of glycerol-3-phosphate YP_002921654.1 with UgpEC is involved in the uptake of glycerol-3-phosphate YP_002921655.1 with UgpACE is involved in the uptake of glycerol-3-phosphate YP_002921656.1 internal ID: KP5148 YP_002921657.1 internal ID: KP5149 YP_002921658.1 with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_002921659.1 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_002921660.1 Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_002921661.1 LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter YP_002921662.1 internal ID: KP5155 YP_002921663.1 identified by Glimmer2; internal ID: KP5157 YP_002921664.1 internal ID: KP5158 YP_002921665.1 internal ID: KP5159 YP_002921666.1 internal ID: KP5160 YP_002921667.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_002921668.1 internal ID: KP5162 YP_002921669.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_002921670.1 putative ABC transporter, membrane protein YP_002921671.1 putative ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions YP_002921672.1 signal recognition protein receptor; functions in the targeting and insertion of membrane proteins YP_002921673.1 catalyzes the methylation of 16S rRNA at position G966 YP_002921674.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP5169 YP_002921675.1 internal ID: KP5170 YP_002921676.1 internal ID: KP5171 YP_002921677.1 P-type ATPase involved in the export of lead, cadmium, zinc and mercury YP_002921678.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs YP_002921679.1 internal ID: KP5174 YP_002921680.1 internal ID: KP5175 YP_002921681.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5176 YP_002921682.1 internal ID: KP5177 YP_002921683.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5178 YP_002921684.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5179 YP_002921685.1 catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A YP_002921686.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5181 YP_002921687.1 Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains YP_002921688.1 catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate YP_002921689.1 catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose YP_002921690.1 internal ID: KP5186 YP_002921691.1 internal ID: KP5187 YP_002921692.1 internal ID: KP5188 YP_002921693.1 with NikACDE is involved in nickel transport into the cell YP_002921694.1 with NikABDE is involved in nickel transport into the cell YP_002921695.1 with NikABCE is involved in nickel transport into the cell YP_002921696.1 with NikABCD is involved with nickel transport into the cell YP_002921697.1 Inhibits transcription at high concentrations of nickel YP_002921698.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5195 YP_002921699.1 internal ID: KP5196 YP_002921700.1 internal ID: KP5197 YP_002921701.1 internal ID: KP5198 YP_002921702.1 ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress YP_002921703.1 internal ID: KP5200 YP_002921704.1 member of the POT family of peptide transporters; probable proton-dependent peptide transporter function YP_002921705.1 predicted SAM-dependent methyltransferase YP_002921706.1 internal ID: KP5203 YP_002921707.1 internal ID: KP5204 YP_002921708.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5205 YP_002921709.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_002921710.1 internal ID: KP5207 YP_002921711.1 internal ID: KP5208 YP_002921712.1 cytoplasmic; catalyzes the hydrolysis of trehalose to glucose YP_002921713.1 internal ID: KP5210 YP_002921714.1 internal ID: KP5211 YP_002921715.1 internal ID: KP5212 YP_002921716.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5213 YP_002921717.1 internal ID: KP5214 YP_002921718.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5215 YP_002921719.1 internal ID: KP5217 YP_002921720.1 internal ID: KP5218 YP_002921721.1 involved in the transport of C4-dicarboxylates across the membrane YP_002921722.1 HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a putative phosphodiesterase protein from E. coli YP_002921723.1 cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA YP_002921724.1 catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans YP_002921725.1 binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP) YP_002921726.1 polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis YP_002921727.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5226 YP_002921728.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP5228 YP_002921729.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5229 YP_002921730.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5230 YP_002921731.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5231 YP_002921732.1 internal ID: KP5232 YP_002921733.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5233 YP_002921734.1 internal ID: KP5234 YP_002921735.1 internal ID: KP5235 YP_002921736.1 binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP) YP_002921737.1 internal ID: KP5237 YP_002921738.1 internal ID: KP5238 YP_002921739.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP5239 YP_002921740.1 identified by Glimmer2; internal ID: KP5240 YP_002921741.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides YP_002921742.1 DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF YP_002921743.1 internal ID: KP5243 YP_002921744.1 transports peptides consisting of two or three amino acids YP_002921745.1 internal ID: KP5245 YP_002921746.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP5246 YP_002921747.1 internal ID: KP5247 YP_002921748.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5248 YP_002921749.1 catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide YP_002921750.1 internal ID: KP5250 YP_002921751.1 internal ID: KP5251 YP_002921752.1 internal ID: KP5252 YP_002921753.1 internal ID: KP5253 YP_002921754.1 internal ID: KP5254 YP_002921755.1 internal ID: KP5255 YP_002921756.1 internal ID: KP5257 YP_002921757.1 internal ID: KP5258 YP_002921758.1 internal ID: KP5259 YP_002921759.1 internal ID: KP5260 YP_002921760.1 internal ID: KP5261 YP_002921761.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5262 YP_002921762.1 internal ID: KP5263 YP_002921763.1 internal ID: KP5264 YP_002921765.1 internal ID: KP5266 YP_002921766.1 internal ID: KP5267 YP_002921767.1 internal ID: KP5268 YP_002921768.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_002921769.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_002921770.1 internal ID: KP5271 YP_002921771.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5272 YP_002921772.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5273 YP_002921773.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5274 YP_002921774.1 internal ID: KP5275 YP_002921775.1 catalyzes the interconversion of D-xylose to D-xylulose YP_002921776.1 identified by Glimmer2; internal ID: KP5277 YP_002921777.1 periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity YP_002921778.1 with XylFH is part of the high affinity xylose ABC transporter YP_002921779.1 internal ID: KP5280 YP_002921780.1 internal ID: KP5281 YP_002921781.1 internal ID: KP5282 YP_002921782.1 periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds YP_002921783.1 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis YP_002921784.1 internal ID: KP5285 YP_002921785.1 internal ID: KP5286 YP_002921786.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis YP_002921787.1 internal ID: KP5288 YP_002921788.1 internal ID: KP5289 YP_002921789.1 internal ID: KP5290 YP_002921790.1 Acts as a repressor of the mtlAD operon YP_002921791.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP5292 YP_002921792.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5294 YP_002921793.1 internal ID: KP5296 YP_002921794.1 represses the lctPRD operon YP_002921795.1 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration YP_002921796.1 member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates YP_002921797.1 catalyzes the O-acetylation of serine YP_002921798.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_002921799.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_002921800.1 internal ID: KP5303 YP_002921801.1 internal ID: KP5304 YP_002921802.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_002921803.1 internal ID: KP5307 YP_002921804.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP5309 YP_002921805.1 internal ID: KP5310 YP_002921806.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism YP_002921807.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine YP_002921808.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose YP_002921809.1 catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core YP_002921810.1 internal ID: KP5315 YP_002921811.1 internal ID: KP5316 YP_002921812.1 internal ID: KP5317 YP_002921813.1 internal ID: KP5318 YP_002921814.1 internal ID: KP5319 YP_002921815.1 internal ID: KP5320 YP_002921816.1 internal ID: KP5321 YP_002921817.1 internal ID: KP5322 YP_002921818.1 internal ID: KP5323 YP_002921819.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A YP_002921820.1 internal ID: KP5325 YP_002921821.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_002921822.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_002921823.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_002921824.1 required for 70S ribosome assembly YP_002921825.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_002921826.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine YP_002921827.1 catalyzes the formation of dUMP from dUTP YP_002921828.1 identified by Glimmer2; internal ID: KP5333 YP_002921829.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly YP_002921830.1 internal ID: KP5335 YP_002921831.1 internal ID: KP5336 YP_002921832.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_002921833.1 internal ID: KP5338 YP_002921834.1 internal ID: KP5339 YP_002921835.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP5340 YP_002921836.1 internal ID: KP5342 YP_002921837.1 internal ID: KP5343 YP_002921838.1 internal ID: KP5345 YP_002921839.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5346 YP_002921840.1 internal ID: KP5347 YP_002921841.1 internal ID: KP5348 YP_002921842.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5349 YP_002921843.1 this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+ YP_002921844.1 Essential for recycling GMP and indirectly, cGMP YP_002921845.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_002921846.1 internal ID: KP5353 YP_002921847.1 specifically modifies tRNA at position G18 YP_002921848.1 catalyzes branch migration in Holliday junction intermediates YP_002921849.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese YP_002921850.1 internal ID: KP5359 YP_002921851.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5360 YP_002921852.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5361 YP_002921853.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_002921854.1 internal ID: KP5363 YP_002921855.1 internal ID: KP5364 YP_002921856.1 internal ID: KP5365 YP_002921857.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5367 YP_002921858.1 internal ID: KP5368 YP_002921859.1 internal ID: KP5370 YP_002921860.1 internal ID: KP5371 YP_002921861.1 internal ID: KP5373 YP_002921862.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5374 YP_002921863.1 internal ID: KP5375 YP_002921864.1 internal ID: KP5376 YP_002921865.1 internal ID: KP5377 YP_002921866.1 catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides YP_002921867.1 may be involved in the transport of galactosides-pentoses-hexuronides YP_002921868.1 internal ID: KP5380 YP_002921869.1 identified by Glimmer2 and GeneMark.hmm; internal ID: KP5381 YP_002921870.1 identified by GeneMark.hmm; internal ID: KP5383 YP_002921871.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5384 YP_002921872.1 internal ID: KP5385 YP_002921873.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5386 YP_002921874.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5387 YP_002921875.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5388 YP_002921876.1 internal ID: KP5389 YP_002921877.1 internal ID: KP5391 YP_002921878.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5392 YP_002921879.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5393 YP_002921880.1 internal ID: KP5394 YP_002921881.1 internal ID: KP5395 YP_002921882.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5396 YP_002921883.1 internal ID: KP5397 YP_002921884.1 internal ID: KP5398 YP_002921885.1 internal ID: KP5400 YP_002921886.1 internal ID: KP5401 YP_002921887.1 internal ID: KP5402 YP_002921888.1 internal ID: KP5403 YP_002921891.1 internal ID: KP5406 YP_002921892.1 internal ID: KP5407 YP_002921893.1 internal ID: KP5408 YP_002921894.1 internal ID: KP5409 YP_002921895.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5410 YP_002921896.1 belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component YP_002921897.1 internal ID: KP5413 YP_002921898.1 internal ID: KP5414 YP_002921899.1 internal ID: KP5415 YP_002921900.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5416 YP_002921901.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5417 YP_002921902.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5418 YP_002921903.1 internal ID: KP5419 YP_002921904.1 extradiol catechol dioxygenase that catalyzes the oxidative cleavage of substituted catechols; part of the bacterial aromatic compound degradation pathway YP_002921905.1 internal ID: KP5421 YP_002921906.1 internal ID: KP5422 YP_002921907.1 internal ID: KP5423 YP_002921908.1 internal ID: KP5424 YP_002921909.1 internal ID: KP5425 YP_002921910.1 internal ID: KP5426 YP_002921911.1 internal ID: KP5427 YP_002921912.1 internal ID: KP5429 YP_002921913.1 internal ID: KP5430 YP_002921914.1 internal ID: KP5431 YP_002921915.1 internal ID: KP5432 YP_002921916.1 internal ID: KP5434 YP_002921917.1 catalyzes the formation of phosphonoacetaldehyde from 2-aminoethylphosphonate and pyruvate YP_002921918.1 catalyzes the degradation of phosphonoacetaldehyde to acetaldehyde and phosphate YP_002921919.1 experimental results in Escherichia coli suggest that this gene encodes an inosine export protein; member of major facilitator superfamily; MFS YP_002921920.1 internal ID: KP5439 YP_002921921.1 internal ID: KP5440 YP_002921922.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5442 YP_002921923.1 cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate YP_002921924.1 membrane protein regulates uhpT expression YP_002921925.1 Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph YP_002921926.1 response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter YP_002921927.1 with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit YP_002921928.1 internal ID: KP5449 YP_002921929.1 internal ID: KP5450 YP_002921930.1 identified by Glimmer2; internal ID: KP5451 YP_002921931.1 internal ID: KP5452 YP_002921932.1 internal ID: KP5454 YP_002921933.1 multidrug efflux protein involved in adaptation to low energy shock YP_002921934.1 regulates the synthesis and expression of the dsdXA operon and dadA gene YP_002921935.1 member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function YP_002921936.1 catalyzes the formation of pyruvate from serine YP_002921937.1 internal ID: KP5459 YP_002921938.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5460 YP_002921939.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5461 YP_002921940.1 internal ID: KP5462 YP_002921941.1 internal ID: KP5463 YP_002921942.1 internal ID: KP5464 YP_002921943.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5465 YP_002921944.1 internal ID: KP5466 YP_002921945.1 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent YP_002921946.1 with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress YP_002921947.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5469 YP_002921948.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5470 YP_002921949.1 internal ID: KP5472 YP_002921950.1 internal ID: KP5473 YP_002921951.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism YP_002921952.1 internal ID: KP5475 YP_002921953.1 internal ID: KP5476 YP_002921954.1 internal ID: KP5477 YP_002921955.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5478 YP_002921956.1 YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins YP_002921957.1 negatively supercoils closed circular double-stranded DNA YP_002921958.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_002921959.1 binds the polymerase to DNA and acts as a sliding clamp YP_002921960.1 internal ID: KP5483 YP_002921961.1 identified by Glimmer2; internal ID: KP5484 YP_002921962.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_002921963.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_002921964.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria YP_002921965.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_002921966.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5489 YP_002921967.1 Confers resistance to chloramphenicol YP_002921968.1 Involved in anaerobic NO protection YP_002921969.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5492 YP_002921970.1 internal ID: KP5493 YP_002921971.1 internal ID: KP5494 YP_002921972.1 YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily YP_002921973.1 identified by Glimmer2, GeneMark and GeneMark.hmm; internal ID: KP5497 YP_002921974.1 internal ID: KP5498 YP_002921975.1 internal ID: KP5499 YP_002921976.1 identified by Glimmer2; internal ID: KP5501 YP_002921977.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon YP_002921978.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_002921979.1 Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_002921980.1 part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_002921981.1 internal ID: KP5506 YP_002921982.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_002921983.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_002921984.1 identified by Glimmer2; internal ID: KP5509 YP_002921985.1 identified by Glimmer2; internal ID: KP5510 YP_002921986.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_002921987.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_002921988.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_002921989.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_002921990.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_002921991.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_002921992.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_002921993.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_002921994.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation YP_002921995.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_002921996.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs