-- dump date 20140619_121900 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 521045000001 SEQ_END SEQ_END NC_012785.1 2302126 2302126 DR NC_012785.1; contig end 2302126..2302126 Kosmotoga olearia TBF 19.5.1 YP_002939734.1 CDS dnaA NC_012785.1 103 1446 D binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 103..1446 Kosmotoga olearia TBF 19.5.1 7968583 YP_002939735.1 CDS Kole_0002 NC_012785.1 1460 2434 R PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; NADP oxidoreductase coenzyme F420-dependent; KEGG: gbm:Gbem_0008 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Glycerol-3-phosphate dehydrogenase (NAD(P)(+)) complement(1460..2434) Kosmotoga olearia TBF 19.5.1 7968827 YP_002939736.1 CDS Kole_0003 NC_012785.1 2431 3375 R KEGG: aeh:Mlg_0033 tRNA (guanine-N(7)-)-methyltransferase; TIGRFAM: tRNA (guanine-N(7)-)-methyltransferase; PFAM: methyltransferase; Methyltransferase type 11; tRNA (guanine-N(7)-)-methyltransferase complement(2431..3375) Kosmotoga olearia TBF 19.5.1 7968828 YP_002939737.1 CDS Kole_0004 NC_012785.1 3606 4154 D KEGG: mxa:MXAN_5070 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; hypoxanthine phosphoribosyltransferase 3606..4154 Kosmotoga olearia TBF 19.5.1 7968829 YP_002939738.1 CDS Kole_0005 NC_012785.1 4132 4449 D hypothetical protein 4132..4449 Kosmotoga olearia TBF 19.5.1 7968830 YP_002939739.1 CDS Kole_0006 NC_012785.1 4561 6924 D catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 4561..6924 Kosmotoga olearia TBF 19.5.1 7968831 YP_002939740.1 CDS Kole_0007 NC_012785.1 6924 7487 D TIGRFAM: methyltransferase; PFAM: Protein of unknown function methylase ; RNA methylase; KEGG: sat:SYN_00910 adenine-specific methyltransferase; methyltransferase 6924..7487 Kosmotoga olearia TBF 19.5.1 7968832 YP_002939741.1 CDS Kole_0008 NC_012785.1 7484 7960 D PFAM: protein of unknown function DUF82; KEGG: mxa:MXAN_0365 hypothetical protein; hypothetical protein 7484..7960 Kosmotoga olearia TBF 19.5.1 7968833 YP_002939742.1 CDS Kole_0009 NC_012785.1 7968 10667 D KEGG: sus:Acid_1646 PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein; multi-sensor signal transduction histidine kinase 7968..10667 Kosmotoga olearia TBF 19.5.1 7968834 YP_002939743.1 CDS Kole_0010 NC_012785.1 10636 10995 D PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: geo:Geob_1006 response regulator receiver protein; response regulator receiver protein 10636..10995 Kosmotoga olearia TBF 19.5.1 7968835 YP_002939744.1 CDS ileS NC_012785.1 11010 13775 D IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 11010..13775 Kosmotoga olearia TBF 19.5.1 7968836 YP_002939745.1 CDS Kole_0012 NC_012785.1 13900 17469 D PFAM: polysaccharide export protein; KEGG: ppr:PBPRA0349 periplasmic protein involved in polysaccharide export; polysaccharide export protein 13900..17469 Kosmotoga olearia TBF 19.5.1 7968837 YP_002939746.1 CDS Kole_0013 NC_012785.1 17509 18198 D KEGG: sun:SUN_1558 capsular polysaccharide biosynthesis protein; capsular polysaccharide biosynthesis protein 17509..18198 Kosmotoga olearia TBF 19.5.1 7968838 YP_002939747.1 CDS Kole_0014 NC_012785.1 18232 20457 D KEGG: pca:Pcar_1464 uncharacterized exopolysaccharide biosynthesis protein; TIGRFAM: capsular exopolysaccharide family; PFAM: lipopolysaccharide biosynthesis protein; capsular exopolysaccharide family 18232..20457 Kosmotoga olearia TBF 19.5.1 7968839 YP_002939748.1 CDS Kole_0015 NC_012785.1 20454 21197 D PFAM: zinc/iron permease; KEGG: mca:MCA2417 ZIP zinc transporter family protein; zinc/iron permease 20454..21197 Kosmotoga olearia TBF 19.5.1 7968840 YP_002939749.1 CDS Kole_0016 NC_012785.1 21224 24001 D PFAM: O-antigen polymerase; KEGG: dat:HRM2_25580 O-antigen polymerase involved in exopolysaccharide biosynthesis; O-antigen polymerase 21224..24001 Kosmotoga olearia TBF 19.5.1 7968841 YP_002939750.1 CDS Kole_0017 NC_012785.1 24079 25998 D TIGRFAM: methionyl-tRNA synthetase; methionyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase class I (M); t-RNA-binding domain protein; Cysteinyl-tRNA synthetase class Ia; KEGG: bsu:BSU00380 methionyl-tRNA synthetase; methionyl-tRNA synthetase 24079..25998 Kosmotoga olearia TBF 19.5.1 7968842 YP_002939751.1 CDS Kole_0018 NC_012785.1 26015 28453 D KEGG: nam:NAMH_0664 DNA gyrase, A subunit; TIGRFAM: DNA gyrase, A subunit; PFAM: DNA gyrase/topoisomerase IV subunit A; DNA gyrase repeat beta-propeller; SMART: DNA gyrase/topoisomerase IV subunit A; DNA gyrase, A subunit 26015..28453 Kosmotoga olearia TBF 19.5.1 7968843 YP_002939752.1 CDS Kole_0019 NC_012785.1 28473 29099 D KEGG: glo:Glov_1232 transcriptional repressor, LexA family; TIGRFAM: LexA repressor; PFAM: LexA DNA-binding domain protein; peptidase S24 and S26 domain protein; SOS-response transcriptional repressor, LexA 28473..29099 Kosmotoga olearia TBF 19.5.1 7968844 YP_002939753.1 CDS Kole_0020 NC_012785.1 29123 29578 D KEGG: afw:Anae109_2734 ribose 5-phosphate isomerase B; TIGRFAM: ribose 5-phosphate isomerase B; sugar-phosphate isomerase, RpiB/LacA/LacB family; PFAM: Ribose/galactose isomerase; ribose 5-phosphate isomerase B 29123..29578 Kosmotoga olearia TBF 19.5.1 7968845 YP_002939754.1 CDS Kole_0021 NC_012785.1 29575 30540 D PFAM: histone deacetylase superfamily; KEGG: dat:HRM2_13220 histone deacetylase superfamily protein; Histone deacetylase 29575..30540 Kosmotoga olearia TBF 19.5.1 7968846 YP_002939755.1 CDS Kole_0022 NC_012785.1 30600 33110 R PFAM: surface antigen variable number repeat protein; surface antigen (D15); KEGG: tcx:Tcr_1278 surface antigen (D15); surface antigen variable number repeat protein complement(30600..33110) Kosmotoga olearia TBF 19.5.1 7968847 YP_002939756.1 CDS Kole_0023 NC_012785.1 33115 33657 R PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: dat:HRM2_16530 sensory signal transduction histidine kinase (ATPase domain protein); histidine kinase complement(33115..33657) Kosmotoga olearia TBF 19.5.1 7968848 YP_002939757.1 CDS Kole_0024 NC_012785.1 33654 34397 R PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: dat:HRM2_16540 metal-dependent phosphoesterase (PHP family protein); PHP domain protein complement(33654..34397) Kosmotoga olearia TBF 19.5.1 7968849 YP_002939758.1 CDS Kole_0025 NC_012785.1 34394 34726 R KEGG: dat:HRM2_16550 iron-sulfur binding hydrogenase; iron-sulfur binding hydrogenase complement(34394..34726) Kosmotoga olearia TBF 19.5.1 7968850 YP_002939759.1 CDS Kole_0026 NC_012785.1 34766 35722 R PFAM: CBS domain containing protein; ATP-binding region ATPase domain protein; SMART: CBS domain containing protein; KEGG: dat:HRM2_16560 RsbW2; signal transduction protein with CBS domains complement(34766..35722) Kosmotoga olearia TBF 19.5.1 7968851 YP_002939760.1 CDS Kole_0027 NC_012785.1 35719 36084 R KEGG: dat:HRM2_16570 hypothetical protein; hypothetical protein complement(35719..36084) Kosmotoga olearia TBF 19.5.1 7968852 YP_002939761.1 CDS thyX NC_012785.1 36081 36773 R flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor; FAD-dependent thymidylate synthase complement(36081..36773) Kosmotoga olearia TBF 19.5.1 7968853 YP_002939762.1 CDS Kole_0029 NC_012785.1 36785 37957 R KEGG: hypothetical protein; hypothetical protein complement(36785..37957) Kosmotoga olearia TBF 19.5.1 7968854 YP_002939763.1 CDS Kole_0030 NC_012785.1 37947 38768 R KEGG: aba:Acid345_0569 mannose-6-phosphate isomerase; Phosphomannose isomerase-like protein complement(37947..38768) Kosmotoga olearia TBF 19.5.1 7968855 YP_002939764.1 CDS Kole_0031 NC_012785.1 38770 40083 R TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; tRNA (uracil-5-)-methyltransferase Gid complement(38770..40083) Kosmotoga olearia TBF 19.5.1 7968856 YP_002939765.1 CDS Kole_0032 NC_012785.1 40080 40973 R PFAM: 8-oxoguanine DNA glycosylase domain protein; SMART: HhH-GPD family protein; KEGG: OGG1; 8-oxoguanine DNA glycosylase ; K03660 N-glycosylase/DNA lyase; 8-oxoguanine DNA glycosylase domain protein complement(40080..40973) Kosmotoga olearia TBF 19.5.1 7968857 YP_002939766.1 CDS Kole_0033 NC_012785.1 40970 41284 R hypothetical protein complement(40970..41284) Kosmotoga olearia TBF 19.5.1 7968858 YP_002939767.1 CDS Kole_0034 NC_012785.1 41277 42092 R PFAM: protein of unknown function DUF208; KEGG: nis:NIS_0539 hypothetical protein; hypothetical protein complement(41277..42092) Kosmotoga olearia TBF 19.5.1 7968859 YP_002939768.1 CDS Kole_0035 NC_012785.1 42089 42883 R KEGG: EEPD1; endonuclease/exonuclease/phosphatase family domain containing 1; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: helix-hairpin-helix motif; SMART: Helix-hairpin-helix DNA-binding class 1; competence protein ComEA helix-hairpin-helix repeat protein complement(42089..42883) Kosmotoga olearia TBF 19.5.1 7968860 YP_002939769.1 CDS Kole_0036 NC_012785.1 42880 43641 R hypothetical protein complement(42880..43641) Kosmotoga olearia TBF 19.5.1 7968861 YP_002939770.1 CDS Kole_0037 NC_012785.1 43638 44627 R PFAM: 3-dehydroquinate synthase; KEGG: dat:HRM2_06080 AroB1; 3-dehydroquinate synthase complement(43638..44627) Kosmotoga olearia TBF 19.5.1 7968862 YP_002939771.1 CDS Kole_0038 NC_012785.1 44624 45634 R PFAM: peptidase M42 family protein; peptidase M18 aminopeptidase I; peptidase M20; KEGG: bsu:BSU28820 hypothetical protein; peptidase M42 family protein complement(44624..45634) Kosmotoga olearia TBF 19.5.1 7968863 YP_002939772.1 CDS Kole_0039 NC_012785.1 45631 46665 R PFAM: peptidase M42 family protein; KEGG: bha:BH3132 endo-1,4-beta-glucanase; peptidase M42 family protein complement(45631..46665) Kosmotoga olearia TBF 19.5.1 7968864 YP_002939773.1 CDS Kole_0040 NC_012785.1 46655 47677 R PFAM: peptidase M42 family protein; peptidase M18 aminopeptidase I; peptidase M20; KEGG: bha:BH3132 endo-1,4-beta-glucanase; peptidase M42 family protein complement(46655..47677) Kosmotoga olearia TBF 19.5.1 7968865 YP_002939774.1 CDS minC NC_012785.1 47674 48330 R blocks the formation of polar Z-ring septums; septum formation inhibitor complement(47674..48330) Kosmotoga olearia TBF 19.5.1 7968866 YP_002939775.1 CDS Kole_0042 NC_012785.1 48858 49364 D PFAM: 3H domain protein; Helix-turn-helix type 11 domain protein; KEGG: bha:BH1216 transcriptional regulator; 3H domain protein 48858..49364 Kosmotoga olearia TBF 19.5.1 7968870 YP_002939776.1 CDS Kole_0043 NC_012785.1 49390 50667 D PFAM: major facilitator superfamily MFS_1; General substrate transporter; KEGG: abm:ABSDF0216 MFS family transporter; major facilitator superfamily MFS_1 49390..50667 Kosmotoga olearia TBF 19.5.1 7968871 YP_002939777.1 CDS Kole_0044 NC_012785.1 50822 51394 D KEGG: sat:SYN_00663 cytoplasmic protein; cytoplasmic protein 50822..51394 Kosmotoga olearia TBF 19.5.1 7968872 YP_002939778.1 CDS Kole_0045 NC_012785.1 51399 52568 D catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 51399..52568 Kosmotoga olearia TBF 19.5.1 7968873 YP_002939779.1 CDS uvrA NC_012785.1 52745 55573 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A complement(52745..55573) Kosmotoga olearia TBF 19.5.1 7968875 YP_002939780.1 CDS Kole_0047 NC_012785.1 55566 56879 R KEGG: bsu:BSU01770 hypothetical protein; TIGRFAM: phosphoglucosamine mutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase ; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucosamine mutase complement(55566..56879) Kosmotoga olearia TBF 19.5.1 7968876 YP_002939781.1 CDS Kole_0048 NC_012785.1 57103 57921 D KEGG: bsu:BSU00420 dimethyladenosine transferase; TIGRFAM: dimethyladenosine transferase; PFAM: ribosomal RNA adenine methylase transferase; SMART: ribosomal RNA adenine methylase transferase; dimethyladenosine transferase 57103..57921 Kosmotoga olearia TBF 19.5.1 7968878 YP_002939782.1 CDS Kole_0049 NC_012785.1 57914 59626 D KEGG: bsu:BSU24100 transcriptional regulator (sigma-L-dependent); TIGRFAM: PAS sensor protein; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; PAS fold-4 domain protein; PAS fold domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; PAS domain containing protein; PAS modulated sigma54 specific transcriptional regulator, Fis family 57914..59626 Kosmotoga olearia TBF 19.5.1 7968879 YP_002939783.1 CDS Kole_0050 NC_012785.1 60061 60807 R TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: shl:Shal_2747 short-chain dehydrogenase/reductase SDR; 3-oxoacyl-ACP reductase complement(60061..60807) Kosmotoga olearia TBF 19.5.1 7968881 YP_002939784.1 CDS Kole_0051 NC_012785.1 61213 61548 D hypothetical protein 61213..61548 Kosmotoga olearia TBF 19.5.1 7968882 YP_002939785.1 CDS Kole_0052 NC_012785.1 61578 62180 D PFAM: transposase IS4 family protein; KEGG: dol:Dole_3091 transposase IS4 family protein; transposase IS4 family protein 61578..62180 Kosmotoga olearia TBF 19.5.1 7968883 YP_002939786.1 CDS Kole_0053 NC_012785.1 62582 66382 D KEGG: eck:EC55989_2911 hypothetical protein; hypothetical protein 62582..66382 Kosmotoga olearia TBF 19.5.1 7968884 YP_002939787.1 CDS Kole_0054 NC_012785.1 66591 67436 D KEGG: Rap/Ran GTPase-activating protein; hypothetical protein 66591..67436 Kosmotoga olearia TBF 19.5.1 7968885 YP_002939788.1 CDS Kole_0055 NC_012785.1 67539 69281 D PFAM: protein of unknown function DUF262; KEGG: see:SNSL254_A4878 hypothetical protein; hypothetical protein 67539..69281 Kosmotoga olearia TBF 19.5.1 7968886 YP_002939789.1 CDS Kole_0056 NC_012785.1 69397 70290 D KEGG: acp:A2cp1_4010 restriction endonuclease-like protein; hypothetical protein 69397..70290 Kosmotoga olearia TBF 19.5.1 7968887 YP_002939790.1 CDS Kole_0057 NC_012785.1 70413 71135 R PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: atc:AGR_L_50 hypothetical protein; IstB domain protein ATP-binding protein complement(70413..71135) Kosmotoga olearia TBF 19.5.1 7968888 YP_002939791.1 CDS Kole_0058 NC_012785.1 71143 72612 R PFAM: Integrase catalytic region; KEGG: gur:Gura_2875 integrase catalytic subunit; Integrase catalytic region complement(71143..72612) Kosmotoga olearia TBF 19.5.1 7968889 YP_002939792.1 CDS Kole_0059 NC_012785.1 72722 73309 D hypothetical protein 72722..73309 Kosmotoga olearia TBF 19.5.1 7968890 YP_002939793.1 CDS Kole_0060 NC_012785.1 73366 73581 D KEGG: rfe:RF_1071 transposase; transposase 73366..73581 Kosmotoga olearia TBF 19.5.1 7968891 YP_002939794.1 CDS Kole_0061 NC_012785.1 73638 76265 R KEGG: eta:ETA_pET090040 DNA restriction subunit type III restriction and modification system; PFAM: type III restriction protein res subunit; SMART: DEAD-like helicase; Type III site-specific deoxyribonuclease complement(73638..76265) Kosmotoga olearia TBF 19.5.1 7968892 YP_002939795.1 CDS Kole_0062 NC_012785.1 76258 78309 R PFAM: DNA methylase N-4/N-6 domain protein; KEGG: hip:CGSHiEE_06790 type III restriction/modification system modification methylase; DNA methylase N-4/N-6 domain protein complement(76258..78309) Kosmotoga olearia TBF 19.5.1 7968893 YP_002939796.1 CDS Kole_0063 NC_012785.1 78311 78526 R TIGRFAM: DNA binding domain protein, excisionase family; KEGG: vvy:VV2209 hypothetical protein; DNA binding domain protein, excisionase family complement(78311..78526) Kosmotoga olearia TBF 19.5.1 7968894 YP_002939797.1 CDS Kole_0064 NC_012785.1 78519 78959 R KEGG: eta:ETA_pET090030 DNA recognition and methylase subunit Mod; DNA recognition and methylase subunit Mod complement(78519..78959) Kosmotoga olearia TBF 19.5.1 7968895 YP_002939798.1 CDS Kole_0065 NC_012785.1 79272 79994 R PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: bha:BH3999 transposase (26); IstB domain protein ATP-binding protein complement(79272..79994) Kosmotoga olearia TBF 19.5.1 7968896 YP_002939799.1 CDS Kole_0066 NC_012785.1 80025 81101 R KEGG: bha:BH3998 transposase (25); transposase (25) complement(80025..81101) Kosmotoga olearia TBF 19.5.1 7968897 YP_002939800.1 CDS Kole_0067 NC_012785.1 81157 81582 D KEGG: cje:Cj1602 conserved hypothetical protein Cj1602; hypothetical protein 81157..81582 Kosmotoga olearia TBF 19.5.1 7968898 YP_002939801.1 CDS Kole_0068 NC_012785.1 81975 82241 R hypothetical protein complement(81975..82241) Kosmotoga olearia TBF 19.5.1 7968899 YP_002939802.1 CDS Kole_0069 NC_012785.1 82512 83846 D SMART: AAA ATPase; KEGG: sat:SYN_01506 ATPase; AAA ATPase 82512..83846 Kosmotoga olearia TBF 19.5.1 7968900 YP_002939803.1 CDS Kole_0071 NC_012785.1 85101 85502 R PFAM: transposase IS3/IS911 family protein; KEGG: pst:PSPTO_5508 ISPsy8, transposase OrfA; transposase IS3/IS911 family protein complement(85101..85502) Kosmotoga olearia TBF 19.5.1 7968902 YP_002939804.1 CDS Kole_0072 NC_012785.1 85578 85769 D hypothetical protein 85578..85769 Kosmotoga olearia TBF 19.5.1 7968903 YP_002939805.1 CDS Kole_0073 NC_012785.1 85901 87112 R KEGG: abu:Abu_1480 hypothetical protein; hypothetical protein complement(85901..87112) Kosmotoga olearia TBF 19.5.1 7968904 YP_002939806.1 CDS Kole_0074 NC_012785.1 88310 89644 D SMART: AAA ATPase; KEGG: sat:SYN_01506 ATPase; AAA ATPase 88310..89644 Kosmotoga olearia TBF 19.5.1 7968905 YP_002939807.1 CDS Kole_0075 NC_012785.1 90329 90442 D hypothetical protein 90329..90442 Kosmotoga olearia TBF 19.5.1 7968906 YP_002939808.1 CDS Kole_0076 NC_012785.1 90600 90776 D hypothetical protein 90600..90776 Kosmotoga olearia TBF 19.5.1 7968907 YP_002939809.1 CDS Kole_0077 NC_012785.1 91104 91520 D hypothetical protein 91104..91520 Kosmotoga olearia TBF 19.5.1 7967495 YP_002939810.1 CDS Kole_0078 NC_012785.1 91571 92653 R KEGG: AGAP004514-PA; hypothetical protein complement(91571..92653) Kosmotoga olearia TBF 19.5.1 7967496 YP_002939811.1 CDS Kole_0079 NC_012785.1 92897 94258 R SMART: AAA ATPase; KEGG: cbd:CBUD_1375 hypothetical ATPase; AAA ATPase complement(92897..94258) Kosmotoga olearia TBF 19.5.1 7967497 YP_002939812.1 CDS Kole_0080 NC_012785.1 94791 95756 D PFAM: protein of unknown function DUF534; KEGG: hch:HCH_04501 ABC-type uncharacterized transport system, periplasmic component; hypothetical protein 94791..95756 Kosmotoga olearia TBF 19.5.1 7967498 YP_002939813.1 CDS Kole_0081 NC_012785.1 95762 96721 D PFAM: inner-membrane translocator; KEGG: atc:AGR_C_4842 probable ABC transporter, permease protein; inner-membrane translocator 95762..96721 Kosmotoga olearia TBF 19.5.1 7967499 YP_002939814.1 CDS Kole_0082 NC_012785.1 96718 97467 D PFAM: ABC transporter related; SMC domain protein; SMART: AAA ATPase; KEGG: bxe:Bxe_C1111 ABC transporter, ATPase subunit; ABC transporter 96718..97467 Kosmotoga olearia TBF 19.5.1 7967500 YP_002939815.1 CDS Kole_0083 NC_012785.1 99173 99412 D PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: atc:AGR_C_418 hypothetical protein; XRE family transcriptional regulator 99173..99412 Kosmotoga olearia TBF 19.5.1 7967501 YP_002939816.1 CDS Kole_0084 NC_012785.1 99409 99702 D SMART: helix-turn-helix domain protein; XRE family transcriptional regulator 99409..99702 Kosmotoga olearia TBF 19.5.1 7967502 YP_002939817.1 CDS Kole_0085 NC_012785.1 99880 100740 R PFAM: aminotransferase class IV; KEGG: tgr:Tgr7_2706 D-amino-acid transaminase; aminotransferase class IV complement(99880..100740) Kosmotoga olearia TBF 19.5.1 7967503 YP_002939818.1 CDS Kole_0086 NC_012785.1 100737 101081 R KEGG: ppr:PBPRB1691 hypothetical protein; hypothetical protein complement(100737..101081) Kosmotoga olearia TBF 19.5.1 7967504 YP_002939819.1 CDS Kole_0087 NC_012785.1 101153 101956 R TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase; KEGG: afw:Anae109_3653 phosphodiesterase; phosphodiesterase, MJ0936 family complement(101153..101956) Kosmotoga olearia TBF 19.5.1 7967505 YP_002939820.1 CDS Kole_0088 NC_012785.1 102411 103001 D PFAM: plasmid pRiA4b ORF-3 family protein; KEGG: afw:Anae109_1544 plasmid pRiA4b ORF-3 family protein; plasmid pRiA4b ORF-3 family protein 102411..103001 Kosmotoga olearia TBF 19.5.1 7967506 YP_002939821.1 CDS Kole_0089 NC_012785.1 103140 104168 D hypothetical protein 103140..104168 Kosmotoga olearia TBF 19.5.1 7967507 YP_002939822.1 CDS Kole_0090 NC_012785.1 104385 105008 D PFAM: cyclase family protein; KEGG: baa:BA_0933 hypothetical protein; cyclase family protein 104385..105008 Kosmotoga olearia TBF 19.5.1 7967508 YP_002939823.1 CDS Kole_0091 NC_012785.1 105188 105706 D PFAM: flavin reductase domain protein FMN-binding; KEGG: sat:SYN_02123 ferric-chelate reductase / rubredoxin; flavin reductase domain protein FMN-binding 105188..105706 Kosmotoga olearia TBF 19.5.1 7967509 YP_002939824.1 CDS Kole_0092 NC_012785.1 106424 107710 D catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase 106424..107710 Kosmotoga olearia TBF 19.5.1 7967510 YP_002939825.1 CDS Kole_0093 NC_012785.1 107679 108875 D TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: fph:Fphi_0553 argininosuccinate lyase; argininosuccinate lyase 107679..108875 Kosmotoga olearia TBF 19.5.1 7967511 YP_002939826.1 CDS argC NC_012785.1 108872 109891 D catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 108872..109891 Kosmotoga olearia TBF 19.5.1 7967512 YP_002939827.1 CDS argJ NC_012785.1 109907 111100 D bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein 109907..111100 Kosmotoga olearia TBF 19.5.1 7967513 YP_002939828.1 CDS Kole_0096 NC_012785.1 111097 111945 D catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 111097..111945 Kosmotoga olearia TBF 19.5.1 7967514 YP_002939829.1 CDS Kole_0097 NC_012785.1 111948 113147 D catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; acetylornithine aminotransferase 111948..113147 Kosmotoga olearia TBF 19.5.1 7967515 YP_002939830.1 CDS Kole_0098 NC_012785.1 113672 115282 D PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: sse:Ssed_3778 response regulator; metal dependent phosphohydrolase 113672..115282 Kosmotoga olearia TBF 19.5.1 7967516 YP_002939831.1 CDS Kole_0099 NC_012785.1 115908 116315 D PFAM: flavin reductase domain protein FMN-binding; KEGG: sat:SYN_02123 ferric-chelate reductase / rubredoxin; flavin reductase domain protein FMN-binding 115908..116315 Kosmotoga olearia TBF 19.5.1 7967517 YP_002939832.1 CDS Kole_0100 NC_012785.1 116341 117465 R PFAM: transposase mutator type; KEGG: sun:SUN_2453 transposase; transposase mutator type complement(116341..117465) Kosmotoga olearia TBF 19.5.1 7967518 YP_002939833.1 CDS Kole_0101 NC_012785.1 117562 117873 D PFAM: Rubredoxin-type Fe(Cys)4 protein; KEGG: sat:SYN_02123 ferric-chelate reductase / rubredoxin; Rubredoxin-type Fe(Cys)4 protein 117562..117873 Kosmotoga olearia TBF 19.5.1 7967519 YP_002939834.1 CDS Kole_0102 NC_012785.1 117934 119034 R PFAM: aminotransferase class-III; KEGG: hdu:HD0892 acetylornithine aminotransferase; aminotransferase class-III complement(117934..119034) Kosmotoga olearia TBF 19.5.1 7967520 YP_002939835.1 CDS Kole_0103 NC_012785.1 119046 120245 R catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase complement(119046..120245) Kosmotoga olearia TBF 19.5.1 7967521 YP_002939836.1 CDS Kole_0104 NC_012785.1 120265 120963 R PFAM: Tetrahydrodipicolinate succinyltransferase domain protein; transferase hexapeptide repeat containing protein; KEGG: bha:BH2669 tetrahydrodipicolinate succinylase; tetrahydrodipicolinate succinyltransferase complement(120265..120963) Kosmotoga olearia TBF 19.5.1 7967522 YP_002939837.1 CDS Kole_0105 NC_012785.1 120960 121595 R KEGG: zmo:ZMO0707 dihydrodipicolinate reductase; TIGRFAM: dihydrodipicolinate reductase; PFAM: dihydrodipicolinate reductase; dihydrodipicolinate reductase complement(120960..121595) Kosmotoga olearia TBF 19.5.1 7967523 YP_002939838.1 CDS Kole_0106 NC_012785.1 121592 122476 R TIGRFAM: dihydrodipicolinate synthase; PFAM: dihydrodipicolinate synthetase; KEGG: sat:SYN_02161 dihydrodipicolinate synthase; dihydrodipicolinate synthase complement(121592..122476) Kosmotoga olearia TBF 19.5.1 7967524 YP_002939839.1 CDS Kole_0107 NC_012785.1 122446 123159 R KEGG: dps:DP0433 diaminopimelate epimerase; TIGRFAM: diaminopimelate epimerase; PFAM: diaminopimelate epimerase; diaminopimelate epimerase complement(122446..123159) Kosmotoga olearia TBF 19.5.1 7967525 YP_002939840.1 CDS Kole_0108 NC_012785.1 123156 124124 R KEGG: sfu:Sfum_3032 aspartate-semialdehyde dehydrogenase; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase NAD - binding; Semialdehyde dehydrogenase dimerisation region; aspartate-semialdehyde dehydrogenase complement(123156..124124) Kosmotoga olearia TBF 19.5.1 7967526 YP_002939841.1 CDS Kole_0109 NC_012785.1 124769 124969 R PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: amc:MADE_03487 cold shock-like protein CspG; cold-shock DNA-binding domain protein complement(124769..124969) Kosmotoga olearia TBF 19.5.1 7967527 YP_002939842.1 CDS Kole_0110 NC_012785.1 125629 127308 D PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: ppd:Ppro_2725 PAS/PAC sensor signal transduction histidine kinase; histidine kinase 125629..127308 Kosmotoga olearia TBF 19.5.1 7967528 YP_002939843.1 CDS Kole_0111 NC_012785.1 127358 128551 D KEGG: dal:Dalk_4664 response regulator receiver modulated metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; response regulator receiver; Metal-dependent hydrolase HDOD; SMART: response regulator receiver; metal-dependent phosphohydrolase HD region; response regulator receiver modulated metal dependent phosphohydrolase 127358..128551 Kosmotoga olearia TBF 19.5.1 7967529 YP_002939844.1 CDS Kole_0112 NC_012785.1 129526 129795 D KEGG: rru:Rru_A3210 DNA methylase N-4/N-6; DNA methylase N-4/N-6 129526..129795 Kosmotoga olearia TBF 19.5.1 7967530 YP_002939845.1 CDS Kole_0114 NC_012785.1 130606 130896 R PFAM: transposase IS3/IS911 family protein; KEGG: nha:Nham_4140 transposase IS3/IS911; transposase IS3/IS911 family protein complement(130606..130896) Kosmotoga olearia TBF 19.5.1 7967532 YP_002939846.1 CDS Kole_0116 NC_012785.1 131539 132291 D PFAM: DNA methylase N-4/N-6 domain protein; KEGG: pub:SAR11_0109 site-specific DNA methyltransferase; DNA methylase N-4/N-6 domain protein 131539..132291 Kosmotoga olearia TBF 19.5.1 7967534 YP_002939847.1 CDS Kole_0117 NC_012785.1 133355 133792 D KEGG: neu:NE1602 general secretion pathway protein G; hypothetical protein 133355..133792 Kosmotoga olearia TBF 19.5.1 7967535 YP_002939848.1 CDS Kole_0118 NC_012785.1 133939 134946 D KEGG: cja:CJA_2729 pilin; hypothetical protein 133939..134946 Kosmotoga olearia TBF 19.5.1 7967536 YP_002939849.1 CDS Kole_0119 NC_012785.1 134983 135324 R PFAM: protein of unknown function DUF202; hypothetical protein complement(134983..135324) Kosmotoga olearia TBF 19.5.1 7967537 YP_002939850.1 CDS Kole_0120 NC_012785.1 135387 136679 R PFAM: amino acid permease-associated region; Spore germination protein; KEGG: nis:NIS_0790 amino acid transporter; amino acid permease-associated region complement(135387..136679) Kosmotoga olearia TBF 19.5.1 7967538 YP_002939851.1 CDS Kole_0121 NC_012785.1 136936 138015 R TIGRFAM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; PFAM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; KEGG: gbm:Gbem_1976 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase complement(136936..138015) Kosmotoga olearia TBF 19.5.1 7967540 YP_002939852.1 CDS Kole_0122 NC_012785.1 138405 139097 D hypothetical protein 138405..139097 Kosmotoga olearia TBF 19.5.1 7967541 YP_002939853.1 CDS Kole_0123 NC_012785.1 139136 139858 D PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; ionotropic glutamate receptor; KEGG: dde:Dde_0186 extracellular solute-binding protein; extracellular solute-binding protein family 3 139136..139858 Kosmotoga olearia TBF 19.5.1 7967542 YP_002939854.1 CDS Kole_0124 NC_012785.1 139938 140558 D TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: dat:HRM2_20380 GlnP5; polar amino acid ABC transporter, inner membrane subunit 139938..140558 Kosmotoga olearia TBF 19.5.1 7967543 YP_002939855.1 CDS Kole_0125 NC_012785.1 140555 141325 D PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sfu:Sfum_3901 ABC transporter related; ABC transporter 140555..141325 Kosmotoga olearia TBF 19.5.1 7967544 YP_002939856.1 CDS Kole_0126 NC_012785.1 141322 141996 D TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: dat:HRM2_14040 GlnP2; polar amino acid ABC transporter, inner membrane subunit 141322..141996 Kosmotoga olearia TBF 19.5.1 7967545 YP_002939857.1 CDS Kole_0127 NC_012785.1 142019 143515 D catalyzes the degradation of histidine to urocanate and ammmonia; histidine ammonia-lyase 142019..143515 Kosmotoga olearia TBF 19.5.1 7967546 YP_002939858.1 CDS Kole_0128 NC_012785.1 143686 144267 R PFAM: regulatory protein TetR; KEGG: bar:GBAA2479 TetR family transcriptional regulator; TetR family transcriptional regulator complement(143686..144267) Kosmotoga olearia TBF 19.5.1 7967548 YP_002939859.1 CDS Kole_0129 NC_012785.1 144268 144717 R hypothetical protein complement(144268..144717) Kosmotoga olearia TBF 19.5.1 7967549 YP_002939860.1 CDS Kole_0130 NC_012785.1 144727 145368 R hypothetical protein complement(144727..145368) Kosmotoga olearia TBF 19.5.1 7967550 YP_002939861.1 CDS Kole_0131 NC_012785.1 145355 146737 R PFAM: major facilitator superfamily MFS_1; KEGG: bar:GBAA4216 EmrB/QacA family drug resistance transporter; major facilitator superfamily MFS_1 complement(145355..146737) Kosmotoga olearia TBF 19.5.1 7967551 YP_002939862.1 CDS Kole_0132 NC_012785.1 146904 147950 R PFAM: TrkA-N domain protein; Ion transport 2 domain protein ; TrkA-C domain protein; KEGG: dal:Dalk_2078 TrkA-N domain protein; TrkA-N domain protein complement(146904..147950) Kosmotoga olearia TBF 19.5.1 7967552 YP_002939863.1 CDS Kole_0133 NC_012785.1 148036 149994 D PFAM: UvrD/REP helicase; KEGG: sat:SYN_02537 UvrD/rep helicase; UvrD/REP helicase 148036..149994 Kosmotoga olearia TBF 19.5.1 7967553 YP_002939864.1 CDS hppA NC_012785.1 150034 152205 D pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient; membrane-bound proton-translocating pyrophosphatase 150034..152205 Kosmotoga olearia TBF 19.5.1 7967554 YP_002939865.1 CDS Kole_0135 NC_012785.1 152314 153843 D PFAM: nucleic acid binding OB-fold tRNA/helicase-type; KEGG: sus:Acid_0157 PAS/PAC sensor hybrid histidine kinase; nucleic acid binding OB-fold tRNA/helicase-type 152314..153843 Kosmotoga olearia TBF 19.5.1 7967555 YP_002939866.1 CDS Kole_0136 NC_012785.1 153869 154708 D PFAM: nuclease (SNase domain protein); SMART: nuclease (SNase domain protein); KEGG: bsu:BSU21610 hypothetical protein; nuclease (SNase domain protein) 153869..154708 Kosmotoga olearia TBF 19.5.1 7967556 YP_002939867.1 CDS Kole_0137 NC_012785.1 154792 155457 D hypothetical protein 154792..155457 Kosmotoga olearia TBF 19.5.1 7967557 YP_002939868.1 CDS Kole_0138 NC_012785.1 155652 156944 R PFAM: transposase IS116/IS110/IS902 family protein; transposase IS111A/IS1328/IS1533; KEGG: bxe:Bxe_B2763 transposase IS110; transposase IS116/IS110/IS902 family protein complement(155652..156944) Kosmotoga olearia TBF 19.5.1 7967558 YP_002939869.1 CDS Kole_0139 NC_012785.1 157229 157525 R PFAM: Excinuclease ABC C subunit domain protein; SMART: Excinuclease ABC C subunit domain protein; KEGG: fph:Fphi_0656 endonuclease; excinuclease ABC subunit C complement(157229..157525) Kosmotoga olearia TBF 19.5.1 7967559 YP_002939870.1 CDS Kole_0140 NC_012785.1 157796 159067 R PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron maturase-specific domain protein; KEGG: ppr:PBPRB0807 maturase; RNA-directed DNA polymerase (Reverse transcriptase) complement(157796..159067) Kosmotoga olearia TBF 19.5.1 7967560 YP_002939871.1 CDS Kole_0141 NC_012785.1 159222 159335 R hypothetical protein complement(159222..159335) Kosmotoga olearia TBF 19.5.1 7967561 YP_002939872.1 CDS Kole_0142 NC_012785.1 159947 160144 R hypothetical protein complement(159947..160144) Kosmotoga olearia TBF 19.5.1 7967562 YP_002939873.1 CDS Kole_0143 NC_012785.1 160409 162199 R KEGG: swi:Swit_4521 membrane-like protein; membrane protein-like protein complement(160409..162199) Kosmotoga olearia TBF 19.5.1 7967563 YP_002939874.1 CDS Kole_0144 NC_012785.1 162232 162723 R PFAM: Ferritin Dps family protein; KEGG: gbm:Gbem_2519 ferritin Dps family protein; Ferroxidase complement(162232..162723) Kosmotoga olearia TBF 19.5.1 7967564 YP_002939875.1 CDS Kole_0145 NC_012785.1 162846 163979 D PFAM: FAD dependent oxidoreductase; monooxygenase FAD-binding; KEGG: noc:Noc_0982 geranylgeranyl reductase; FAD dependent oxidoreductase 162846..163979 Kosmotoga olearia TBF 19.5.1 7967565 YP_002939876.1 CDS Kole_0146 NC_012785.1 163976 165160 R PFAM: aminotransferase class I and II; KEGG: ypg:YpAngola_A2760 aminotransferase, classes I and II; aminotransferase class I and II complement(163976..165160) Kosmotoga olearia TBF 19.5.1 7967566 YP_002939877.1 CDS Kole_0147 NC_012785.1 165169 165987 R PFAM: ABC-3 protein; transport system permease protein; KEGG: bha:BH1390 hypothetical protein; ABC transporter complement(165169..165987) Kosmotoga olearia TBF 19.5.1 7967567 YP_002939878.1 CDS Kole_0148 NC_012785.1 165984 166733 R PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: baa:BA_4953 cation ABC transporter, ATP-binding protein; ABC transporter complement(165984..166733) Kosmotoga olearia TBF 19.5.1 7967568 YP_002939879.1 CDS Kole_0149 NC_012785.1 166720 167598 R PFAM: periplasmic solute binding protein; KEGG: pap:PSPA7_2852 adhesion protein; periplasmic solute binding protein complement(166720..167598) Kosmotoga olearia TBF 19.5.1 7967569 YP_002939880.1 CDS Kole_0150 NC_012785.1 167595 168053 R PFAM: ferric-uptake regulator; KEGG: cjd:JJD26997_1557 ferric uptake regulation protein; ferric uptake regulator, Fur family complement(167595..168053) Kosmotoga olearia TBF 19.5.1 7967570 YP_002939881.1 CDS Kole_0151 NC_012785.1 168141 169817 R KEGG: baa:BA_3885 ABC-2 type transport system permease protein; hypothetical protein complement(168141..169817) Kosmotoga olearia TBF 19.5.1 7967571 YP_002939882.1 CDS Kole_0152 NC_012785.1 169774 170532 R PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bar:GBAA3387 ABC transporter ATP-binding protein; ABC transporter complement(169774..170532) Kosmotoga olearia TBF 19.5.1 7967572 YP_002939883.1 CDS Kole_0153 NC_012785.1 170546 171406 R PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sus:Acid_3750 ABC transporter related; ABC transporter complement(170546..171406) Kosmotoga olearia TBF 19.5.1 7967573 YP_002939884.1 CDS Kole_0154 NC_012785.1 171388 171762 R PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: bsu:BSU30460 hypothetical protein; GntR family transcriptional regulator complement(171388..171762) Kosmotoga olearia TBF 19.5.1 7967574 YP_002939885.1 CDS Kole_0155 NC_012785.1 171779 172549 R hypothetical protein complement(171779..172549) Kosmotoga olearia TBF 19.5.1 7967575 YP_002939886.1 CDS Kole_0156 NC_012785.1 172769 173530 R PFAM: DNA polymerase beta domain protein region; KEGG: hypothetical protein; DNA polymerase beta domain protein region complement(172769..173530) Kosmotoga olearia TBF 19.5.1 7968307 YP_002939887.1 CDS Kole_0157 NC_012785.1 173773 174138 R PFAM: protein of unknown function DUF1667; KEGG: sat:SYN_02448 zinc finger protein; hypothetical protein complement(173773..174138) Kosmotoga olearia TBF 19.5.1 7968309 YP_002939888.1 CDS Kole_0158 NC_012785.1 174135 175373 R PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sat:SYN_02447 pyridine nucleotide-disulphide oxidoreductase family protein; FAD-dependent pyridine nucleotide-disulfide oxidoreductase complement(174135..175373) Kosmotoga olearia TBF 19.5.1 7968310 YP_002939889.1 CDS Kole_0159 NC_012785.1 175370 176815 R PFAM: FAD dependent oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: NAD(FAD)-dependent dehydrogenase; FAD dependent oxidoreductase complement(175370..176815) Kosmotoga olearia TBF 19.5.1 7968311 YP_002939890.1 CDS Kole_0160 NC_012785.1 177136 177906 D PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; SMART: regulatory protein DeoR; KEGG: set:SEN1438 regulatory protein; DeoR family transcriptional regulator 177136..177906 Kosmotoga olearia TBF 19.5.1 7968312 YP_002939891.1 CDS Kole_0161 NC_012785.1 177918 178700 D PFAM: photosystem I assembly BtpA; KEGG: jan:Jann_2112 photosystem I assembly BtpA; photosystem I assembly BtpA 177918..178700 Kosmotoga olearia TBF 19.5.1 7968313 YP_002939892.1 CDS Kole_0162 NC_012785.1 178672 179937 D PFAM: carbohydrate kinase FGGY; KEGG: rru:Rru_A1267 carbohydrate kinase, FGGY; carbohydrate kinase FGGY 178672..179937 Kosmotoga olearia TBF 19.5.1 7968314 YP_002939893.1 CDS Kole_0163 NC_012785.1 179961 180752 D PFAM: short-chain dehydrogenase/reductase SDR; NAD-dependent epimerase/dehydratase; KEGG: ara:Arad_9891 short chain dehydrogenase protein; short-chain dehydrogenase/reductase SDR 179961..180752 Kosmotoga olearia TBF 19.5.1 7968315 YP_002939894.1 CDS Kole_0164 NC_012785.1 180794 181615 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rru:Rru_A1263 binding-protein dependent transport system inner membrane protein; binding-protein-dependent transport systems inner membrane component 180794..181615 Kosmotoga olearia TBF 19.5.1 7968316 YP_002939895.1 CDS Kole_0165 NC_012785.1 181655 182917 D PFAM: extracellular solute-binding protein family 1; KEGG: rru:Rru_A1262 extracellular solute-binding protein; extracellular solute-binding protein family 1 181655..182917 Kosmotoga olearia TBF 19.5.1 7968317 YP_002939896.1 CDS Kole_0166 NC_012785.1 182935 183828 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rru:Rru_A1261 binding-protein dependent transport system inner membrane protein; binding-protein-dependent transport systems inner membrane component 182935..183828 Kosmotoga olearia TBF 19.5.1 7968318 YP_002939897.1 CDS Kole_0167 NC_012785.1 183865 184638 D PFAM: inositol monophosphatase; KEGG: mgm:Mmc1_0078 inositol-phosphate phosphatase; inositol monophosphatase 183865..184638 Kosmotoga olearia TBF 19.5.1 7968319 YP_002939898.1 CDS Kole_0168 NC_012785.1 184831 185370 D PFAM: glycerol-3-phosphate responsive antiterminator; KEGG: baa:BA_1143 dihydroorotate dehydrogenase; glycerol-3-phosphate responsive antiterminator, GlpP 184831..185370 Kosmotoga olearia TBF 19.5.1 7968320 YP_002939899.1 CDS Kole_0169 NC_012785.1 185419 189942 R PFAM: Fibronectin type III domain protein; SMART: Fibronectin type III domain protein; KEGG: hypothetical protein; Fibronectin type III domain protein complement(185419..189942) Kosmotoga olearia TBF 19.5.1 7968321 YP_002939900.1 CDS Kole_0170 NC_012785.1 189955 191253 R KEGG: afw:Anae109_1868 hypothetical protein; hypothetical protein complement(189955..191253) Kosmotoga olearia TBF 19.5.1 7968322 YP_002939901.1 CDS Kole_0171 NC_012785.1 191354 192274 D PFAM: sugar transferase; KEGG: azo:azo3193 glycosyltransferase; sugar transferase 191354..192274 Kosmotoga olearia TBF 19.5.1 7968323 YP_002939902.1 CDS Kole_0172 NC_012785.1 192345 194099 R TIGRFAM: hydrogenase, Fe-only; PFAM: hydrogenase large subunit domain protein; iron hydrogenase small subunit; ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sfu:Sfum_0844 hydrogenases, Fe-only; hydrogenase, Fe-only complement(192345..194099) Kosmotoga olearia TBF 19.5.1 7968324 YP_002939903.1 CDS Kole_0173 NC_012785.1 194262 196637 R TIGRFAM: leucyl-tRNA synthetase; KEGG: bsu:BSU30320 leucyl-tRNA synthetase; leucyl-tRNA synthetase complement(194262..196637) Kosmotoga olearia TBF 19.5.1 7968325 YP_002939904.1 CDS Kole_0174 NC_012785.1 196763 197890 R PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA4111 transporter; major facilitator superfamily MFS_1 complement(196763..197890) Kosmotoga olearia TBF 19.5.1 7968326 YP_002939905.1 CDS Kole_0175 NC_012785.1 198050 199315 R PFAM: extracellular solute-binding protein family 1; KEGG: kpe:KPK_4987 ABC transporter, periplasmic substrate-binding protein; extracellular solute-binding protein family 1 complement(198050..199315) Kosmotoga olearia TBF 19.5.1 7968327 YP_002939906.1 CDS Kole_0176 NC_012785.1 199356 199937 R KEGG: sat:SYN_02876 dephospho-CoA kinase; TIGRFAM: dephospho-CoA kinase; PFAM: Dephospho-CoA kinase; dephospho-CoA kinase complement(199356..199937) Kosmotoga olearia TBF 19.5.1 7968328 YP_002939907.1 CDS Kole_0177 NC_012785.1 199937 200203 R hypothetical protein complement(199937..200203) Kosmotoga olearia TBF 19.5.1 7968329 YP_002939908.1 CDS Kole_0178 NC_012785.1 200200 201561 R catalyzes the formation of D-fructose 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate isomerase complement(200200..201561) Kosmotoga olearia TBF 19.5.1 7968330 YP_002939909.1 CDS Kole_0179 NC_012785.1 201575 202087 R KEGG: sus:Acid_7098 adenine phosphoribosyltransferase; TIGRFAM: adenine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; adenine phosphoribosyltransferase complement(201575..202087) Kosmotoga olearia TBF 19.5.1 7968331 YP_002939910.1 CDS Kole_0180 NC_012785.1 202244 202738 D PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: pca:Pcar_1846 NADP-reducing hydrogenase chain A; NADH dehydrogenase (ubiquinone) 24 kDa subunit 202244..202738 Kosmotoga olearia TBF 19.5.1 7968332 YP_002939911.1 CDS Kole_0181 NC_012785.1 202738 203115 D KEGG: dat:HRM2_16520 NADP-reducing hydrogenase, subunit B; NADP-reducing hydrogenase, subunit B 202738..203115 Kosmotoga olearia TBF 19.5.1 7968333 YP_002939912.1 CDS Kole_0182 NC_012785.1 203131 204930 D PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dat:HRM2_16600 NuoF; NADH dehydrogenase (quinone) 203131..204930 Kosmotoga olearia TBF 19.5.1 7968334 YP_002939913.1 CDS Kole_0183 NC_012785.1 205002 205505 D PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: pca:Pcar_0833 NADH:ubiquinone oxidoreductase 24 kD subunit; NADH dehydrogenase (ubiquinone) 24 kDa subunit 205002..205505 Kosmotoga olearia TBF 19.5.1 7968335 YP_002939914.1 CDS Kole_0184 NC_012785.1 205502 207121 D PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; KEGG: dat:HRM2_16600 NuoF; NADH dehydrogenase (quinone) 205502..207121 Kosmotoga olearia TBF 19.5.1 7968336 YP_002939915.1 CDS Kole_0185 NC_012785.1 207193 208014 D KEGG: bap:BUAP5A_259 membrane-bound lytic murein transglycosylase E; hypothetical protein 207193..208014 Kosmotoga olearia TBF 19.5.1 7968337 YP_002939916.1 CDS Kole_0186 NC_012785.1 208020 209510 D PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: vpa:VP2077 maltodextrin glucosidase; alpha amylase catalytic region 208020..209510 Kosmotoga olearia TBF 19.5.1 7968338 YP_002939917.1 CDS Kole_0187 NC_012785.1 209515 210432 D PFAM: protein of unknown function DUF6 transmembrane; KEGG: bsu:BSU02210 hypothetical protein; hypothetical protein 209515..210432 Kosmotoga olearia TBF 19.5.1 7968339 YP_002939918.1 CDS Kole_0188 NC_012785.1 210365 210823 R KEGG: glo:Glov_2047 methylated-DNA/protein-cysteine methyltransferase; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; methylated-DNA/protein-cysteine methyltransferase complement(210365..210823) Kosmotoga olearia TBF 19.5.1 7968340 YP_002939919.1 CDS Kole_0189 NC_012785.1 210837 214358 R TIGRFAM: chromosome segregation protein SMC; PFAM: SMC domain protein; SMCs flexible hinge domain protein; KEGG: bha:BH2487 chromosome segregation SMC protein; chromosome segregation protein SMC complement(210837..214358) Kosmotoga olearia TBF 19.5.1 7968341 YP_002939920.1 CDS Kole_0190 NC_012785.1 214370 215419 R PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: dal:Dalk_4810 radical SAM domain protein; Radical SAM domain protein complement(214370..215419) Kosmotoga olearia TBF 19.5.1 7968342 YP_002939921.1 CDS Kole_0191 NC_012785.1 216068 216271 R hypothetical protein complement(216068..216271) Kosmotoga olearia TBF 19.5.1 7968343 YP_002939922.1 CDS Kole_0192 NC_012785.1 216631 218505 R PFAM: LVIVD repeat protein; KEGG: dal:Dalk_1645 LVIVD repeat protein; LVIVD repeat protein complement(216631..218505) Kosmotoga olearia TBF 19.5.1 7968344 YP_002939923.1 CDS Kole_0193 NC_012785.1 219146 219259 R hypothetical protein complement(219146..219259) Kosmotoga olearia TBF 19.5.1 7968345 YP_002939924.1 CDS Kole_0195 NC_012785.1 221059 221157 R hypothetical protein complement(221059..221157) Kosmotoga olearia TBF 19.5.1 7968347 YP_002939925.1 CDS Kole_0196 NC_012785.1 221282 222016 D PFAM: cytochrome c biogenesis protein transmembrane region; KEGG: dol:Dole_0130 cytochrome c biogenesis protein transmembrane region; cytochrome c biogenesis protein transmembrane region 221282..222016 Kosmotoga olearia TBF 19.5.1 7968348 YP_002939926.1 CDS Kole_0197 NC_012785.1 222029 222706 D KEGG: dat:HRM2_42220 thioredoxin; Thioredoxin-related protein-like protein 222029..222706 Kosmotoga olearia TBF 19.5.1 7968349 YP_002939927.1 CDS Kole_0198 NC_012785.1 222927 223742 D PFAM: protein of unknown function DUF125 transmembrane; KEGG: hypothetical protein; hypothetical protein 222927..223742 Kosmotoga olearia TBF 19.5.1 7968350 YP_002939928.1 CDS Kole_0199 NC_012785.1 223726 224289 R PFAM: Appr-1-p processing domain protein; SMART: Appr-1-p processing domain protein; KEGG: Appr-1-p processing enzyme family protein; Appr-1-p processing domain protein complement(223726..224289) Kosmotoga olearia TBF 19.5.1 7968351 YP_002939929.1 CDS Kole_0200 NC_012785.1 224663 225904 R TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: sfu:Sfum_0727 ammonium transporter; ammonium transporter complement(224663..225904) Kosmotoga olearia TBF 19.5.1 7968352 YP_002939930.1 CDS Kole_0201 NC_012785.1 226509 227792 R PFAM: AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: gme:Gmet_0939 recombination factor protein RarA; recombination factor protein RarA complement(226509..227792) Kosmotoga olearia TBF 19.5.1 7968353 YP_002939931.1 CDS Kole_0202 NC_012785.1 227779 228720 R PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; KEGG: mxa:MXAN_3507 UDP-glucose 4-epimerase; NAD-dependent epimerase/dehydratase complement(227779..228720) Kosmotoga olearia TBF 19.5.1 7968354 YP_002939932.1 CDS Kole_0203 NC_012785.1 228731 229354 R TIGRFAM: phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase superfamily; KEGG: sat:SYN_02178 uracil DNA glycosylase superfamily protein; phage SPO1 DNA polymerase-related protein complement(228731..229354) Kosmotoga olearia TBF 19.5.1 7968355 YP_002939933.1 CDS Kole_0204 NC_012785.1 229374 233774 R PFAM: permease YjgP/YjgQ family protein; KEGG: dvl:Dvul_1425 permease YjgP/YjgQ family protein; permease YjgP/YjgQ family protein complement(229374..233774) Kosmotoga olearia TBF 19.5.1 7968356 YP_002939934.1 CDS Kole_0205 NC_012785.1 233799 234491 R PFAM: PhoU family protein; KEGG: glo:Glov_0622 phosphate uptake regulator, PhoU; phosphate uptake regulator, PhoU complement(233799..234491) Kosmotoga olearia TBF 19.5.1 7968357 YP_002939935.1 CDS Kole_0206 NC_012785.1 234481 235305 R PFAM: ATP-NAD/AcoX kinase; KEGG: tdn:Suden_1085 NAD(+) kinase; ATP-NAD/AcoX kinase complement(234481..235305) Kosmotoga olearia TBF 19.5.1 7968358 YP_002939936.1 CDS Kole_0207 NC_012785.1 235315 235632 R PFAM: protein of unknown function YGGT; KEGG: gur:Gura_1165 protein of unknown function YGGT; hypothetical protein complement(235315..235632) Kosmotoga olearia TBF 19.5.1 7968359 YP_002939937.1 CDS Kole_0208 NC_012785.1 235645 236673 R KEGG: sfu:Sfum_0993 Holliday junction DNA helicase B; TIGRFAM: Holliday junction DNA helicase RuvB; PFAM: AAA ATPase central domain protein; Holliday junction DNA helicase RuvB domain; Chromosomal replication initiator DnaA; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; Holliday junction DNA helicase RuvB complement(235645..236673) Kosmotoga olearia TBF 19.5.1 7968360 YP_002939938.1 CDS Kole_0209 NC_012785.1 236683 237981 R TIGRFAM: asparaginyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; KEGG: bsu:BSU22360 asparaginyl-tRNA synthetase; asparaginyl-tRNA synthetase complement(236683..237981) Kosmotoga olearia TBF 19.5.1 7968361 YP_002939939.1 CDS Kole_0210 NC_012785.1 238088 239485 R PFAM: S-layer domain protein; KEGG: hypothetical protein; S-layer domain protein complement(238088..239485) Kosmotoga olearia TBF 19.5.1 7968362 YP_002939940.1 CDS Kole_0211 NC_012785.1 239587 241362 D TIGRFAM: aspartyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); tRNA synthetase class II (G H P and S); GAD domain protein; nucleic acid binding OB-fold tRNA/helicase-type; KEGG: bar:GBAA4632 aspartyl-tRNA synthetase; aspartyl-tRNA synthetase 239587..241362 Kosmotoga olearia TBF 19.5.1 7968363 YP_002939941.1 CDS Kole_0212 NC_012785.1 241359 242009 D TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region; KEGG: geo:Geob_2362 cytidylate kinase; cytidylate kinase 241359..242009 Kosmotoga olearia TBF 19.5.1 7968364 YP_002939942.1 CDS Kole_0213 NC_012785.1 242006 242902 D KEGG: gsu:GSU2604 penicillin tolerance protein LytB; TIGRFAM: hydroxymethylbutenyl pyrophosphate reductase; PFAM: LytB protein; hydroxymethylbutenyl pyrophosphate reductase 242006..242902 Kosmotoga olearia TBF 19.5.1 7968365 YP_002939943.1 CDS Kole_0214 NC_012785.1 242886 244604 D PFAM: RNA binding S1 domain protein; SMART: RNA binding S1 domain protein; KEGG: mxa:MXAN_3793 30S ribosomal protein S1; RNA binding S1 domain protein 242886..244604 Kosmotoga olearia TBF 19.5.1 7968366 YP_002939944.1 CDS engA NC_012785.1 244604 245932 D EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 244604..245932 Kosmotoga olearia TBF 19.5.1 7968367 YP_002939945.1 CDS Kole_0216 NC_012785.1 245929 246552 D PFAM: protein of unknown function DUF205; KEGG: rlt:Rleg2_1297 protein of unknown function DUF205; hypothetical protein 245929..246552 Kosmotoga olearia TBF 19.5.1 7968368 YP_002939946.1 CDS Kole_0217 NC_012785.1 246570 246986 R TIGRFAM: ATP synthase F1, epsilon subunit; PFAM: H+transporting two-sector ATPase delta/epsilon subunit; KEGG: bha:BH3753 ATP synthase epsilon subunit; ATP synthase F1, epsilon subunit complement(246570..246986) Kosmotoga olearia TBF 19.5.1 7968369 YP_002939947.1 CDS Kole_0218 NC_012785.1 246992 248443 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta complement(246992..248443) Kosmotoga olearia TBF 19.5.1 7968370 YP_002939948.1 CDS Kole_0219 NC_012785.1 248459 249298 R TIGRFAM: ATP synthase F1, gamma subunit; PFAM: H+transporting two-sector ATPase gamma subunit; KEGG: sfu:Sfum_2583 ATP synthase F1, gamma subunit; ATP synthase F1, gamma subunit complement(248459..249298) Kosmotoga olearia TBF 19.5.1 7968371 YP_002939949.1 CDS Kole_0220 NC_012785.1 249309 250817 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha complement(249309..250817) Kosmotoga olearia TBF 19.5.1 7968372 YP_002939950.1 CDS Kole_0221 NC_012785.1 250848 251375 R TIGRFAM: ATP synthase F1, delta subunit; PFAM: H+transporting two-sector ATPase delta (OSCP) subunit; KEGG: abb:ABBFA_003368 ATP synthase F1, delta subunit; ATP synthase F1, delta subunit complement(250848..251375) Kosmotoga olearia TBF 19.5.1 7968373 YP_002939951.1 CDS Kole_0222 NC_012785.1 251372 251857 R TIGRFAM: ATP synthase F0, B subunit; PFAM: H+transporting two-sector ATPase B/B' subunit; KEGG: bha:BH3758 F0F1 ATP synthase subunit B; ATP synthase F0, B subunit complement(251372..251857) Kosmotoga olearia TBF 19.5.1 7968374 YP_002939952.1 CDS Kole_0223 NC_012785.1 251891 252136 R TIGRFAM: ATP synthase F0, C subunit; PFAM: H+transporting two-sector ATPase C subunit; KEGG: dol:Dole_0802 ATP synthase F0, C subunit; ATP synthase F0, C subunit complement(251891..252136) Kosmotoga olearia TBF 19.5.1 7968375 YP_002939953.1 CDS Kole_0224 NC_012785.1 252172 253008 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A complement(252172..253008) Kosmotoga olearia TBF 19.5.1 7968376 YP_002939954.1 CDS Kole_0225 NC_012785.1 253281 253568 R KEGG: mex:Mext_3176 hypothetical protein; hypothetical protein complement(253281..253568) Kosmotoga olearia TBF 19.5.1 7968377 YP_002939955.1 CDS Kole_0226 NC_012785.1 253586 256276 R KEGG: dol:Dole_2573 DNA polymerase I; TIGRFAM: DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease; 3'-5' exonuclease; SMART: 5'-3' exonuclease; DNA-directed DNA polymerase; 3'-5' exonuclease; Helix-hairpin-helix domain protein class 2; DNA polymerase I complement(253586..256276) Kosmotoga olearia TBF 19.5.1 7968378 YP_002939956.1 CDS Kole_0227 NC_012785.1 256279 256623 R TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: Carboxymuconolactone decarboxylase; KEGG: smt:Smal_0827 alkylhydroperoxidase like protein, AhpD family; alkylhydroperoxidase like protein, AhpD family complement(256279..256623) Kosmotoga olearia TBF 19.5.1 7968379 YP_002939957.1 CDS Kole_0228 NC_012785.1 256637 257458 R TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: gme:Gmet_2464 TatD-related deoxyribonuclease:radical SAM family protein; hydrolase, TatD family complement(256637..257458) Kosmotoga olearia TBF 19.5.1 7968380 YP_002939958.1 CDS Kole_0229 NC_012785.1 257409 258488 R PFAM: Protein of unknown function DUF933; KEGG: bha:BH4051 translation-associated GTPase; hypothetical protein complement(257409..258488) Kosmotoga olearia TBF 19.5.1 7968381 YP_002939959.1 CDS Kole_0230 NC_012785.1 258828 259004 D hypothetical protein 258828..259004 Kosmotoga olearia TBF 19.5.1 7968382 YP_002939960.1 CDS Kole_0231 NC_012785.1 259202 260482 D KEGG: lpn:lpg2913 hypothetical protein; hypothetical protein 259202..260482 Kosmotoga olearia TBF 19.5.1 7968383 YP_002939961.1 CDS Kole_0232 NC_012785.1 261104 261451 R PFAM: protein of unknown function DUF86; KEGG: gur:Gura_4166 hypothetical protein; hypothetical protein complement(261104..261451) Kosmotoga olearia TBF 19.5.1 7968384 YP_002939962.1 CDS Kole_0233 NC_012785.1 261444 261746 R PFAM: DNA polymerase beta domain protein region; KEGG: ccs:CCNA_03176 nucleotidyltransferase; DNA polymerase beta domain protein region complement(261444..261746) Kosmotoga olearia TBF 19.5.1 7968385 YP_002939963.1 CDS Kole_0234 NC_012785.1 262494 263051 D KEGG: pde:Pden_5114 DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; DNA polymerase III, epsilon subunit 262494..263051 Kosmotoga olearia TBF 19.5.1 7968386 YP_002939964.1 CDS Kole_0235 NC_012785.1 263054 264343 D PFAM: PhoH family protein; SMART: Nucleotide binding protein PINc; KEGG: geo:Geob_2932 PhoH family protein; PhoH family protein 263054..264343 Kosmotoga olearia TBF 19.5.1 7968387 YP_002939965.1 CDS Kole_0236 NC_012785.1 264363 264605 D hypothetical protein 264363..264605 Kosmotoga olearia TBF 19.5.1 7968225 YP_002939966.1 CDS Kole_0237 NC_012785.1 264583 265635 D TIGRFAM: HAD superfamily (subfamily IIIA) phosphatase, TIGR01668; hydrolase, HAD-superfamily, subfamily IIIA; KEGG: baa:BA_5007 haloacid dehalogenase-like hydrolase; HAD superfamily (subfamily IIIA) phosphatase, TIGR01668 264583..265635 Kosmotoga olearia TBF 19.5.1 7968989 YP_002939967.1 CDS Kole_0238 NC_012785.1 265632 266738 D PFAM: GTP-binding protein HSR1-related; KEGG: baa:BA_5006 MMR_HSR1, GTPase of unknown function; GTP-binding protein HSR1-related 265632..266738 Kosmotoga olearia TBF 19.5.1 7968990 YP_002939968.1 CDS Kole_0239 NC_012785.1 266755 267348 D PFAM: Propanediol utilization protein; KEGG: pmr:PMI2713 propanediol utilization protein; Propanediol utilization protein 266755..267348 Kosmotoga olearia TBF 19.5.1 7968991 YP_002939969.1 CDS Kole_0240 NC_012785.1 267353 268150 D PFAM: protein of unknown function DUF72; KEGG: par:Psyc_1936 hypothetical protein; hypothetical protein 267353..268150 Kosmotoga olearia TBF 19.5.1 7968992 YP_002939970.1 CDS Kole_0241 NC_012785.1 268157 268483 D hypothetical protein 268157..268483 Kosmotoga olearia TBF 19.5.1 7968993 YP_002939971.1 CDS Kole_0242 NC_012785.1 268540 271104 R KEGG: gur:Gura_4193 alpha-glucan phosphorylase; TIGRFAM: alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35; alpha-glucan phosphorylase complement(268540..271104) Kosmotoga olearia TBF 19.5.1 7968994 YP_002939972.1 CDS Kole_0243 NC_012785.1 271912 272277 R PFAM: RNA binding S1 domain protein; SMART: RNA binding S1 domain protein; KEGG: bha:BH0077 hypothetical protein; RNA binding S1 domain protein complement(271912..272277) Kosmotoga olearia TBF 19.5.1 7968995 YP_002939973.1 CDS Kole_0244 NC_012785.1 272337 272546 R TIGRFAM: ribosomal protein L31; PFAM: ribosomal protein L31; KEGG: nam:NAMH_1326 ribosomal protein L31; ribosomal protein L31 complement(272337..272546) Kosmotoga olearia TBF 19.5.1 7968996 YP_002939974.1 CDS Kole_0245 NC_012785.1 272661 273650 D hypothetical protein 272661..273650 Kosmotoga olearia TBF 19.5.1 7968997 YP_002939975.1 CDS Kole_0246 NC_012785.1 273647 274669 D TIGRFAM: S-adenosylmethionine/tRNA-ribosyltransferase-isomerase; PFAM: Queuosine biosynthesis protein; KEGG: bar:GBAA4648 S-adenosylmethionine:tRNA ribosyltransferase-isomerase; S-adenosylmethionine/tRNA-ribosyltransferase- isomerase 273647..274669 Kosmotoga olearia TBF 19.5.1 7968998 YP_002939976.1 CDS Kole_0247 NC_012785.1 274640 276706 R PFAM: protein of unknown function UPF0118; KEGG: bsu:BSU27420 hypothetical protein; hypothetical protein complement(274640..276706) Kosmotoga olearia TBF 19.5.1 7968999 YP_002939977.1 CDS Kole_0248 NC_012785.1 276724 277704 R PFAM: Asparaginase/glutaminase; KEGG: bha:BH1624 L-asparaginase; Asparaginase/glutaminase complement(276724..277704) Kosmotoga olearia TBF 19.5.1 7969000 YP_002939978.1 CDS Kole_0249 NC_012785.1 277686 279341 R PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: bcc:BCc_272 hypothetical protein; Radical SAM domain protein complement(277686..279341) Kosmotoga olearia TBF 19.5.1 7969001 YP_002939979.1 CDS clpX NC_012785.1 279446 280657 D binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 279446..280657 Kosmotoga olearia TBF 19.5.1 7969002 YP_002939980.1 CDS Kole_0251 NC_012785.1 280657 281649 D KEGG: mxa:MXAN_2051 O-sialoglycoprotein endopeptidase; TIGRFAM: metalloendopeptidase, glycoprotease family; PFAM: peptidase M22 glycoprotease; metalloendopeptidase, glycoprotease family 280657..281649 Kosmotoga olearia TBF 19.5.1 7969003 YP_002939981.1 CDS Kole_0252 NC_012785.1 281632 281871 R TIGRFAM: regulatory protein, FmdB family; KEGG: dal:Dalk_4244 regulatory protein, FmdB family; regulatory protein, FmdB family complement(281632..281871) Kosmotoga olearia TBF 19.5.1 7969004 YP_002939982.1 CDS Kole_0253 NC_012785.1 281889 282248 R PFAM: Cupin 2 conserved barrel domain protein; protein of unknown function DUF861 cupin_3; KEGG: sfu:Sfum_1397 cupin 2, conserved barrel domain protein; Cupin 2 conserved barrel domain protein complement(281889..282248) Kosmotoga olearia TBF 19.5.1 7969005 YP_002939983.1 CDS Kole_0254 NC_012785.1 282214 282918 R PFAM: single-stranded nucleic acid binding R3H domain protein; SMART: single-stranded nucleic acid binding R3H domain protein; KEGG: baa:BA_0592 R3H, single-stranded nucleic acids-binding domain; single-stranded nucleic acid binding R3H domain protein complement(282214..282918) Kosmotoga olearia TBF 19.5.1 7969006 YP_002939984.1 CDS Kole_0255 NC_012785.1 282953 284290 R PFAM: 60 kDa inner membrane insertion protein; KEGG: hps:HPSH_07420 inner membrane protein translocase component YidC; 60 kDa inner membrane insertion protein complement(282953..284290) Kosmotoga olearia TBF 19.5.1 7969007 YP_002939985.1 CDS Kole_0256 NC_012785.1 284287 284529 R PFAM: protein of unknown function DUF37; KEGG: bar:GBAA5048 hypothetical protein; hypothetical protein complement(284287..284529) Kosmotoga olearia TBF 19.5.1 7969008 YP_002939986.1 CDS Kole_0257 NC_012785.1 284501 284905 R TIGRFAM: ribonuclease P protein component; PFAM: ribonuclease P protein; KEGG: sat:SYN_01012 ribonuclease P protein component; ribonuclease P protein component complement(284501..284905) Kosmotoga olearia TBF 19.5.1 7969009 YP_002939987.1 CDS Kole_0258 NC_012785.1 284902 285036 R TIGRFAM: ribosomal protein L34; PFAM: ribosomal protein L34; KEGG: dar:Daro_4204 50S ribosomal protein L34; ribosomal protein L34 complement(284902..285036) Kosmotoga olearia TBF 19.5.1 7969010 YP_002939988.1 CDS Kole_0259 NC_012785.1 285191 286795 D PFAM: SMC domain protein; KEGG: bsu:BSU24240 DNA repair and genetic recombination; SMC domain protein 285191..286795 Kosmotoga olearia TBF 19.5.1 7969011 YP_002939989.1 CDS Kole_0260 NC_012785.1 286788 287426 D KEGG: gur:Gura_2690 heat repeat-containing PBS lyase; hypothetical protein 286788..287426 Kosmotoga olearia TBF 19.5.1 7969012 YP_002939990.1 CDS Kole_0261 NC_012785.1 287413 288312 D KEGG: baa:BA_0174 UDP-N-acetylenolpyruvoylglucosamine reductase, FAD-binding domain; TIGRFAM: UDP-N-acetylenolpyruvoylglucosamine reductase; PFAM: UDP-N-acetylenolpyruvoylglucosamine reductase domain protein; FAD linked oxidase domain protein; UDP-N-acetylenolpyruvoylglucosamine reductase 287413..288312 Kosmotoga olearia TBF 19.5.1 7969013 YP_002939991.1 CDS Kole_0262 NC_012785.1 288330 289295 D KEGG: dde:Dde_2946 HflK protein; TIGRFAM: HflK protein; PFAM: band 7 protein; SMART: band 7 protein; HflK protein 288330..289295 Kosmotoga olearia TBF 19.5.1 7969014 YP_002939992.1 CDS Kole_0263 NC_012785.1 289292 290140 D KEGG: dde:Dde_2947 HflC protein; TIGRFAM: HflC protein; PFAM: band 7 protein; SMART: band 7 protein; HflC protein 289292..290140 Kosmotoga olearia TBF 19.5.1 7969015 YP_002939993.1 CDS Kole_0264 NC_012785.1 290143 290769 D PFAM: protein of unknown function UPF0029; KEGG: dat:HRM2_43180 hypothetical protein; hypothetical protein 290143..290769 Kosmotoga olearia TBF 19.5.1 7969016 YP_002939994.1 CDS Kole_0265 NC_012785.1 290791 291630 D PFAM: peptidase M55 D-aminopeptidase; KEGG: pol:Bpro_0135 D-aminopeptidase DppA. Metallo peptidase. MEROPS family M55; peptidase M55 D-aminopeptidase 290791..291630 Kosmotoga olearia TBF 19.5.1 7969017 YP_002939995.1 CDS Kole_0266 NC_012785.1 291668 293320 R KEGG: csa:Csal_1545 peptidoglycan glycosyltransferase; TIGRFAM: penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; penicillin-binding protein 2 complement(291668..293320) Kosmotoga olearia TBF 19.5.1 7969018 YP_002939996.1 CDS Kole_0267 NC_012785.1 293301 293690 R hypothetical protein complement(293301..293690) Kosmotoga olearia TBF 19.5.1 7969019 YP_002939997.1 CDS Kole_0268 NC_012785.1 293693 294394 R hypothetical protein complement(293693..294394) Kosmotoga olearia TBF 19.5.1 7969020 YP_002939998.1 CDS Kole_0269 NC_012785.1 294391 295410 R TIGRFAM: cell shape determining protein, MreB/Mrl family; PFAM: cell shape determining protein MreB/Mrl; KEGG: pca:Pcar_1049 rod shape-determining protein MreB; rod shape-determining protein MreB complement(294391..295410) Kosmotoga olearia TBF 19.5.1 7969021 YP_002939999.1 CDS Kole_0270 NC_012785.1 295613 296008 D TIGRFAM: S-adenosylmethionine decarboxylase proenzyme; PFAM: S-adenosylmethionine decarboxylase related; KEGG: nis:NIS_1526 S-adenosylmethionine decarboxylase proenzyme; S-adenosylmethionine decarboxylase proenzyme 295613..296008 Kosmotoga olearia TBF 19.5.1 7969022 YP_002940000.1 CDS Kole_0271 NC_012785.1 296023 296889 D catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 296023..296889 Kosmotoga olearia TBF 19.5.1 7969023 YP_002940001.1 CDS Kole_0272 NC_012785.1 297239 299053 D binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 297239..299053 Kosmotoga olearia TBF 19.5.1 7969024 YP_002940002.1 CDS Kole_0273 NC_012785.1 299067 299933 D KEGG: gme:Gmet_2994 endonuclease IV; TIGRFAM: apurinic endonuclease Apn1; PFAM: Xylose isomerase domain protein TIM barrel; SMART: AP endonuclease family 2; apurinic endonuclease Apn1 299067..299933 Kosmotoga olearia TBF 19.5.1 7969025 YP_002940003.1 CDS pyrG NC_012785.1 299917 301521 D CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 299917..301521 Kosmotoga olearia TBF 19.5.1 7969026 YP_002940004.1 CDS Kole_0275 NC_012785.1 301518 302348 D KEGG: pin:Ping_0812 dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS; dihydropteroate synthase 301518..302348 Kosmotoga olearia TBF 19.5.1 7969027 YP_002940005.1 CDS Kole_0276 NC_012785.1 302397 303728 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bha:BH1865 sugar transport system (permease) (binding protein dependent transporter); binding-protein-dependent transport systems inner membrane component 302397..303728 Kosmotoga olearia TBF 19.5.1 7969028 YP_002940006.1 CDS Kole_0277 NC_012785.1 303738 306152 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rlt:Rleg2_5335 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 303738..306152 Kosmotoga olearia TBF 19.5.1 7969029 YP_002940007.1 CDS Kole_0278 NC_012785.1 306176 306379 D hypothetical protein 306176..306379 Kosmotoga olearia TBF 19.5.1 7969030 YP_002940008.1 CDS Kole_0279 NC_012785.1 306376 307161 D KEGG: baa:BA_2669 protein-L-IsoD(D-D) O-methyltransferase (PCMT); hypothetical protein 306376..307161 Kosmotoga olearia TBF 19.5.1 7969031 YP_002940009.1 CDS miaA NC_012785.1 307158 308084 D IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 307158..308084 Kosmotoga olearia TBF 19.5.1 7969032 YP_002940010.1 CDS Kole_0281 NC_012785.1 308077 308316 D TIGRFAM: RNA chaperone Hfq; PFAM: Like-Sm ribonucleoprotein core; KEGG: bha:BH2365 RNA-binding protein Hfq; RNA chaperone Hfq 308077..308316 Kosmotoga olearia TBF 19.5.1 7969033 YP_002940011.1 CDS Kole_0282 NC_012785.1 308432 309571 D TIGRFAM: GTP-binding proten HflX; PFAM: GTP-binding protein HSR1-related; KEGG: aca:ACP_1034 GTP-binding protein HflX; GTP-binding proten HflX 308432..309571 Kosmotoga olearia TBF 19.5.1 7969034 YP_002940012.1 CDS Kole_0283 NC_012785.1 309568 310581 D hypothetical protein 309568..310581 Kosmotoga olearia TBF 19.5.1 7969035 YP_002940013.1 CDS Kole_0284 NC_012785.1 310588 310914 D hypothetical protein 310588..310914 Kosmotoga olearia TBF 19.5.1 7969036 YP_002940014.1 CDS Kole_0285 NC_012785.1 310941 312125 D KEGG: bha:BH3300 S-adenosylmethionine synthetase; TIGRFAM: S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase; S-adenosylmethionine synthetase 310941..312125 Kosmotoga olearia TBF 19.5.1 7969037 YP_002940015.1 CDS Kole_0286 NC_012785.1 312174 312470 D TIGRFAM: ribosomal protein S20; PFAM: ribosomal protein S20; KEGG: afr:AFE_2188 ribosomal protein S20; ribosomal protein S20 312174..312470 Kosmotoga olearia TBF 19.5.1 7969038 YP_002940016.1 CDS Kole_0287 NC_012785.1 312555 313688 R PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: bha:BH1140 sugar ABC transportor ATP-binding protein; ABC transporter complement(312555..313688) Kosmotoga olearia TBF 19.5.1 7969039 YP_002940017.1 CDS Kole_0288 NC_012785.1 313681 313959 R TIGRFAM: prevent-host-death family protein; PFAM: protein of unknown function DUF172; KEGG: rsq:Rsph17025_3797 hypothetical protein; prevent-host-death family protein complement(313681..313959) Kosmotoga olearia TBF 19.5.1 7969040 YP_002940018.1 CDS Kole_0289 NC_012785.1 314082 314612 D hypothetical protein 314082..314612 Kosmotoga olearia TBF 19.5.1 7969041 YP_002940019.1 CDS Kole_0290 NC_012785.1 314642 315967 R KEGG: bsu:BSU17460 glutamine synthetase; TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; glutamine synthetase, type I complement(314642..315967) Kosmotoga olearia TBF 19.5.1 7969042 YP_002940020.1 CDS Kole_0291 NC_012785.1 316091 317470 D KEGG: scl:sce3150 IMP cyclohydrolase; AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)-like protein 316091..317470 Kosmotoga olearia TBF 19.5.1 7969043 YP_002940021.1 CDS Kole_0292 NC_012785.1 317810 318274 R KEGG: hypothetical protein; hypothetical protein complement(317810..318274) Kosmotoga olearia TBF 19.5.1 7969045 YP_002940022.1 CDS Kole_0293 NC_012785.1 318519 319964 D PFAM: Radical SAM domain protein; KEGG: gsu:GSU0244 radical SAM domain-containing protein; Radical SAM domain protein 318519..319964 Kosmotoga olearia TBF 19.5.1 7969046 YP_002940023.1 CDS Kole_0294 NC_012785.1 319999 320559 D PFAM: regulatory protein TetR; KEGG: sfu:Sfum_3459 TetR family transcriptional regulator; TetR family transcriptional regulator 319999..320559 Kosmotoga olearia TBF 19.5.1 7969047 YP_002940024.1 CDS Kole_0295 NC_012785.1 320597 321433 R PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: vpa:VPA1741 hypothetical protein; RpiR family transcriptional regulator complement(320597..321433) Kosmotoga olearia TBF 19.5.1 7969048 YP_002940025.1 CDS Kole_0296 NC_012785.1 321435 322436 R PFAM: basic membrane lipoprotein; KEGG: cvi:CV_2467 membrane lipoprotein; basic membrane lipoprotein complement(321435..322436) Kosmotoga olearia TBF 19.5.1 7969049 YP_002940026.1 CDS Kole_0297 NC_012785.1 322616 323857 R PFAM: Glu/Leu/Phe/Val dehydrogenase ; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: bpt:Bpet2493 glutamate dehydrogenase; Glu/Leu/Phe/Val dehydrogenase complement(322616..323857) Kosmotoga olearia TBF 19.5.1 7969050 YP_002940027.1 CDS Kole_0298 NC_012785.1 323882 324073 R hypothetical protein complement(323882..324073) Kosmotoga olearia TBF 19.5.1 7969051 YP_002940028.1 CDS Kole_0299 NC_012785.1 324396 325628 D PFAM: glycosyl transferase group 1; KEGG: mxa:MXAN_0781 glycosyl transferase, group 1 family protein; glycosyl transferase group 1 324396..325628 Kosmotoga olearia TBF 19.5.1 7969052 YP_002940029.1 CDS Kole_0300 NC_012785.1 326386 327540 R PFAM: ROK family protein; KEGG: aca:ACP_1127 ROK family protein; ROK family protein complement(326386..327540) Kosmotoga olearia TBF 19.5.1 7969053 YP_002940030.1 CDS Kole_0301 NC_012785.1 327567 328403 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mmw:Mmwyl1_2010 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component complement(327567..328403) Kosmotoga olearia TBF 19.5.1 7969054 YP_002940031.1 CDS Kole_0302 NC_012785.1 328400 329284 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mca:MCA1942 sugar ABC transporter, permease protein; binding-protein-dependent transport systems inner membrane component complement(328400..329284) Kosmotoga olearia TBF 19.5.1 7969055 YP_002940032.1 CDS Kole_0303 NC_012785.1 329352 330515 R PFAM: extracellular solute-binding protein family 1; KEGG: ara:Arad_8312 sugar ABC transporter; extracellular solute-binding protein family 1 complement(329352..330515) Kosmotoga olearia TBF 19.5.1 7969056 YP_002940033.1 CDS Kole_0304 NC_012785.1 330733 331347 D PFAM: deoxynucleoside kinase; KEGG: baa:BA_0609 dNK, deoxynucleoside kinase; deoxynucleoside kinase 330733..331347 Kosmotoga olearia TBF 19.5.1 7969057 YP_002940034.1 CDS Kole_0305 NC_012785.1 331344 332351 D PFAM: peptidase U61 LD-carboxypeptidase A; KEGG: dol:Dole_0590 peptidase U61 LD-carboxypeptidase A; peptidase U61 LD-carboxypeptidase A 331344..332351 Kosmotoga olearia TBF 19.5.1 7969058 YP_002940035.1 CDS Kole_0306 NC_012785.1 332400 333365 R PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein; KEGG: dal:Dalk_2405 thioredoxin reductase; FAD-dependent pyridine nucleotide-disulfide oxidoreductase complement(332400..333365) Kosmotoga olearia TBF 19.5.1 7969059 YP_002940036.1 CDS Kole_0307 NC_012785.1 333381 334028 R TIGRFAM: glutaredoxin-like domain protein; PFAM: glutaredoxin; KEGG: ank:AnaeK_2804 glutaredoxin-like domain protein; glutaredoxin-like domain protein complement(333381..334028) Kosmotoga olearia TBF 19.5.1 7969060 YP_002940037.1 CDS Kole_0308 NC_012785.1 334092 334643 R hypothetical protein complement(334092..334643) Kosmotoga olearia TBF 19.5.1 7969061 YP_002940038.1 CDS Kole_0309 NC_012785.1 334649 335575 R PFAM: band 7 protein; SMART: band 7 protein; KEGG: mca:MCA3112 SPFH domain-containing protein/band 7 family protein; band 7 protein complement(334649..335575) Kosmotoga olearia TBF 19.5.1 7969062 YP_002940039.1 CDS Kole_0310 NC_012785.1 335588 336037 R PFAM: protein of unknown function DUF107; KEGG: sfu:Sfum_2309 protein of unknown function DUF107; hypothetical protein complement(335588..336037) Kosmotoga olearia TBF 19.5.1 7969063 YP_002940040.1 CDS Kole_0311 NC_012785.1 336049 336900 R KEGG: hypothetical protein; hypothetical protein complement(336049..336900) Kosmotoga olearia TBF 19.5.1 7969064 YP_002940041.1 CDS Kole_0312 NC_012785.1 336904 337359 R TIGRFAM: ribosomal protein L9; PFAM: ribosomal protein L9; KEGG: nam:NAMH_1270 ribosomal protein L9; ribosomal protein L9 complement(336904..337359) Kosmotoga olearia TBF 19.5.1 7969065 YP_002940042.1 CDS Kole_0313 NC_012785.1 337413 337640 R TIGRFAM: ribosomal protein S18; PFAM: ribosomal protein S18; KEGG: nis:NIS_1166 30S ribosomal protein S18; ribosomal protein S18 complement(337413..337640) Kosmotoga olearia TBF 19.5.1 7969066 YP_002940043.1 CDS Kole_0314 NC_012785.1 337655 338107 R TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; nucleic acid binding OB-fold tRNA/helicase-type; KEGG: sat:SYN_00925 single-strand DNA binding protein; single-strand binding protein complement(337655..338107) Kosmotoga olearia TBF 19.5.1 7969067 YP_002940044.1 CDS rpsF NC_012785.1 338110 338565 R binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 complement(338110..338565) Kosmotoga olearia TBF 19.5.1 7969068 YP_002940045.1 CDS Kole_0316 NC_012785.1 338770 339237 R PFAM: protein of unknown function DUF523; KEGG: saz:Sama_3292 hypothetical protein; hypothetical protein complement(338770..339237) Kosmotoga olearia TBF 19.5.1 7969069 YP_002940046.1 CDS Kole_0317 NC_012785.1 339239 340099 R PFAM: Peptidase M23; Peptidoglycan-binding LysM; SMART: Peptidoglycan-binding LysM; KEGG: afw:Anae109_0789 peptidase M23B; Peptidase M23 complement(339239..340099) Kosmotoga olearia TBF 19.5.1 7968908 YP_002940047.1 CDS Kole_0318 NC_012785.1 340096 340527 R PFAM: diacylglycerol kinase; KEGG: cha:CHAB381_0614 diacylglycerol kinase; diacylglycerol kinase complement(340096..340527) Kosmotoga olearia TBF 19.5.1 7968909 YP_002940048.1 CDS Kole_0319 NC_012785.1 340524 341129 R PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: sat:SYN_02500 pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit; pyruvate ferredoxin/flavodoxin oxidoreductase complement(340524..341129) Kosmotoga olearia TBF 19.5.1 7968910 YP_002940049.1 CDS Kole_0320 NC_012785.1 341136 341963 R catalyzes the coenzyme A-dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin; 2-oxoglutarate ferredoxin oxidoreductase subunit beta complement(341136..341963) Kosmotoga olearia TBF 19.5.1 7968911 YP_002940050.1 CDS Kole_0321 NC_012785.1 341966 342478 R PFAM: CMP/dCMP deaminase zinc-binding; KEGG: gur:Gura_2185 dCMP deaminase; CMP/dCMP deaminase zinc-binding complement(341966..342478) Kosmotoga olearia TBF 19.5.1 7968912 YP_002940051.1 CDS Kole_0322 NC_012785.1 342483 342941 R PFAM: Rubrerythrin; KEGG: sfu:Sfum_3220 rubrerythrin; Rubrerythrin complement(342483..342941) Kosmotoga olearia TBF 19.5.1 7968913 YP_002940052.1 CDS Kole_0323 NC_012785.1 342925 344073 R KEGG: gur:Gura_0208 oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; PFAM: HemN domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; oxygen-independent coproporphyrinogen III oxidase complement(342925..344073) Kosmotoga olearia TBF 19.5.1 7968914 YP_002940053.1 CDS Kole_0324 NC_012785.1 344073 344906 R hypothetical protein complement(344073..344906) Kosmotoga olearia TBF 19.5.1 7968915 YP_002940054.1 CDS gatB NC_012785.1 344903 346348 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B complement(344903..346348) Kosmotoga olearia TBF 19.5.1 7968916 YP_002940055.1 CDS Kole_0326 NC_012785.1 346350 347777 R KEGG: bha:BH0666 aspartyl/glutamyl-tRNA amidotransferase subunit A; TIGRFAM: glutamyl-tRNA(Gln) amidotransferase, A subunit; PFAM: Amidase; glutamyl-tRNA(Gln) amidotransferase, A subunit complement(346350..347777) Kosmotoga olearia TBF 19.5.1 7968917 YP_002940056.1 CDS Kole_0327 NC_012785.1 347887 348708 D PFAM: ribosomal L11 methyltransferase; Methyltransferase type 11; methyltransferase small; Methyltransferase type 12; KEGG: cla:Cla_1260 ribosomal protein L11 methyltransferase; ribosomal L11 methyltransferase 347887..348708 Kosmotoga olearia TBF 19.5.1 7968918 YP_002940057.1 CDS Kole_0328 NC_012785.1 348678 349214 D PFAM: protein of unknown function DUF501; KEGG: csa:Csal_3040 hypothetical protein; hypothetical protein 348678..349214 Kosmotoga olearia TBF 19.5.1 7968919 YP_002940058.1 CDS uvrC NC_012785.1 349204 350928 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 349204..350928 Kosmotoga olearia TBF 19.5.1 7968920 YP_002940059.1 CDS Kole_0330 NC_012785.1 350963 351235 R PFAM: histone family protein DNA-binding protein; SMART: histone family protein DNA-binding protein; KEGG: pla:Plav_3229 histone family protein DNA-binding protein; histone family protein DNA-binding protein complement(350963..351235) Kosmotoga olearia TBF 19.5.1 7968921 YP_002940060.1 CDS Kole_0331 NC_012785.1 351635 352732 D KEGG: bha:BH0491 hypothetical protein; Xaa-Pro aminopeptidase-like protein 351635..352732 Kosmotoga olearia TBF 19.5.1 7968922 YP_002940061.1 CDS Kole_0332 NC_012785.1 352894 353271 D PFAM: transposase IS3/IS911 family protein; KEGG: net:Neut_1719 transposase IS3/IS911 family protein; transposase IS3/IS911 family protein 352894..353271 Kosmotoga olearia TBF 19.5.1 7968923 YP_002940062.1 CDS Kole_0333 NC_012785.1 353298 354200 D PFAM: Integrase catalytic region; KEGG: ypy:YPK_3925 integrase catalytic region; Integrase catalytic region 353298..354200 Kosmotoga olearia TBF 19.5.1 7968924 YP_002940063.1 CDS Kole_0334 NC_012785.1 354397 354597 R hypothetical protein complement(354397..354597) Kosmotoga olearia TBF 19.5.1 7968925 YP_002940064.1 CDS Kole_0335 NC_012785.1 354575 355759 R PFAM: Integrase catalytic region; KEGG: bja:bll1898 transposase; Integrase catalytic region complement(354575..355759) Kosmotoga olearia TBF 19.5.1 7968926 YP_002940065.1 CDS Kole_0336 NC_012785.1 356392 356655 D PFAM: Stage V sporulation protein S; KEGG: bha:BH2375 stage V sporulation protein S; Stage V sporulation protein S 356392..356655 Kosmotoga olearia TBF 19.5.1 7968932 YP_002940066.1 CDS Kole_0337 NC_012785.1 356682 358697 R PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: eli:ELI_03145 alpha-amylase; alpha amylase catalytic region complement(356682..358697) Kosmotoga olearia TBF 19.5.1 7968933 YP_002940067.1 CDS Kole_0338 NC_012785.1 359039 359353 D TIGRFAM: ribosomal protein L21; PFAM: ribosomal protein L21; KEGG: csa:Csal_0474 LSU ribosomal protein L21P; ribosomal protein L21 359039..359353 Kosmotoga olearia TBF 19.5.1 7968935 YP_002940068.1 CDS rpmA NC_012785.1 359370 359621 D involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 359370..359621 Kosmotoga olearia TBF 19.5.1 7968936 YP_002940069.1 CDS Kole_0340 NC_012785.1 359668 360192 D TIGRFAM: ribosomal protein L13; PFAM: ribosomal protein L13; KEGG: dal:Dalk_2692 ribosomal protein L13; 50S ribosomal protein L13 359668..360192 Kosmotoga olearia TBF 19.5.1 7968937 YP_002940070.1 CDS rpsI NC_012785.1 360208 360612 D forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 360208..360612 Kosmotoga olearia TBF 19.5.1 7968938 YP_002940071.1 CDS Kole_0342 NC_012785.1 360672 362405 D KEGG: gme:Gmet_0394 DNA primase; TIGRFAM: DNA primase; PFAM: DNA primase catalytic core domain; zinc finger CHC2-family protein; TOPRIM domain protein; SMART: zinc finger CHC2-family protein; Toprim sub domain protein; DNA primase 360672..362405 Kosmotoga olearia TBF 19.5.1 7968939 YP_002940072.1 CDS Kole_0343 NC_012785.1 362395 363612 D TIGRFAM: RNA polymerase sigma factor RpoD; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 1.2; sigma-70 1.1 domain protein; sigma-70 region 4 domain protein; KEGG: bha:BH1376 RNA polymerase sigma factor RpoD; RNA polymerase, sigma 70 subunit, RpoD subfamily 362395..363612 Kosmotoga olearia TBF 19.5.1 7968940 YP_002940073.1 CDS Kole_0344 NC_012785.1 363715 363888 D hypothetical protein 363715..363888 Kosmotoga olearia TBF 19.5.1 7968941 YP_002940074.1 CDS Kole_0345 NC_012785.1 363863 364606 D SMART: AAA ATPase; KEGG: abc:ACICU_01440 ABC-type polar amino acid transport system, ATPase component; AAA ATPase 363863..364606 Kosmotoga olearia TBF 19.5.1 7968942 YP_002940075.1 CDS Kole_0346 NC_012785.1 364634 365593 D PFAM: PfkB domain protein; KEGG: baa:BA_4320 1-phosphofructokinase; PfkB domain protein 364634..365593 Kosmotoga olearia TBF 19.5.1 7968943 YP_002940076.1 CDS Kole_0347 NC_012785.1 365598 366050 D PFAM: CBS domain containing protein; SMART: CBS domain containing protein; KEGG: sfu:Sfum_2202 CBS domain containing membrane protein; CBS domain containing membrane protein 365598..366050 Kosmotoga olearia TBF 19.5.1 7968944 YP_002940077.1 CDS Kole_0348 NC_012785.1 366047 367324 D KEGG: geo:Geob_1978 MiaB-like tRNA modifying enzyme; TIGRFAM: MiaB-like tRNA modifying enzyme; RNA modification enzyme, MiaB family; PFAM: Radical SAM domain protein; Protein of unknown function UPF0004; SMART: Elongator protein 3/MiaB/NifB; MiaB-like tRNA modifying enzyme 366047..367324 Kosmotoga olearia TBF 19.5.1 7968945 YP_002940078.1 CDS Kole_0349 NC_012785.1 367287 368144 D PFAM: aminotransferase class IV; KEGG: baa:BA_2352 aminotransferase class IV; aminotransferase class IV 367287..368144 Kosmotoga olearia TBF 19.5.1 7968946 YP_002940079.1 CDS Kole_0350 NC_012785.1 368141 368443 D PFAM: protein of unknown function DUF721; KEGG: gbm:Gbem_3436 hypothetical protein; hypothetical protein 368141..368443 Kosmotoga olearia TBF 19.5.1 7968947 YP_002940080.1 CDS Kole_0351 NC_012785.1 368458 370353 D KEGG: bsu:BSU00060 DNA gyrase subunit B; TIGRFAM: DNA gyrase, B subunit; PFAM: DNA topoisomerase type IIA subunit B region 2 domain protein; DNA gyrase subunit B domain protein; TOPRIM domain protein; ATP-binding region ATPase domain protein; SMART: DNA topoisomerase II; ATP-binding region ATPase domain protein; DNA gyrase, B subunit 368458..370353 Kosmotoga olearia TBF 19.5.1 7968948 YP_002940081.1 CDS Kole_0352 NC_012785.1 370350 370991 D hypothetical protein 370350..370991 Kosmotoga olearia TBF 19.5.1 7968949 YP_002940082.1 CDS Kole_0353 NC_012785.1 370997 372286 D TIGRFAM: cell division protein FtsA; PFAM: cell division protein FtsA; KEGG: ilo:IL0440 cell division ATPase, FtsA; cell division protein FtsA 370997..372286 Kosmotoga olearia TBF 19.5.1 7968950 YP_002940083.1 CDS Kole_0354 NC_012785.1 372276 373331 D GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 372276..373331 Kosmotoga olearia TBF 19.5.1 7968951 YP_002940084.1 CDS Kole_0355 NC_012785.1 373328 375016 D PFAM: type II secretion system protein E; General secretory system II protein E domain protein; SMART: AAA ATPase; KEGG: geo:Geob_3374 type IV-A pilus assembly ATPase PilB; type II secretion system protein E 373328..375016 Kosmotoga olearia TBF 19.5.1 7968952 YP_002940085.1 CDS Kole_0356 NC_012785.1 375167 376189 D PFAM: dihydrodipicolinate reductase; KEGG: ade:Adeh_4039 dihydrodipicolinate reductase; dihydrodipicolinate reductase 375167..376189 Kosmotoga olearia TBF 19.5.1 7968953 YP_002940086.1 CDS Kole_0357 NC_012785.1 376195 376512 D hypothetical protein 376195..376512 Kosmotoga olearia TBF 19.5.1 7968954 YP_002940087.1 CDS Kole_0358 NC_012785.1 376509 377936 D PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rpb:RPB_4420 threonine synthase; Pyridoxal-5'-phosphate-dependent protein beta subunit 376509..377936 Kosmotoga olearia TBF 19.5.1 7968955 YP_002940088.1 CDS Kole_0359 NC_012785.1 377920 378291 D hypothetical protein 377920..378291 Kosmotoga olearia TBF 19.5.1 7968956 YP_002940089.1 CDS Kole_0360 NC_012785.1 378288 380483 D PFAM: D-Lysine 56-aminomutase alpha subunit; cobalamin B12-binding domain protein; KEGG: mxa:MXAN_4388 D-lysine 5,6-aminomutase, alpha subunit; D-Lysine 56-aminomutase alpha subunit 378288..380483 Kosmotoga olearia TBF 19.5.1 7968957 YP_002940090.1 CDS Kole_0361 NC_012785.1 380598 381215 R PFAM: BioY protein; KEGG: sfu:Sfum_1749 BioY protein; BioY protein complement(380598..381215) Kosmotoga olearia TBF 19.5.1 7968958 YP_002940091.1 CDS Kole_0362 NC_012785.1 381350 381766 R PFAM: protein of unknown function UPF0047; KEGG: gur:Gura_2106 hypothetical protein; hypothetical protein complement(381350..381766) Kosmotoga olearia TBF 19.5.1 7968959 YP_002940092.1 CDS Kole_0363 NC_012785.1 381850 382032 R hypothetical protein complement(381850..382032) Kosmotoga olearia TBF 19.5.1 7968960 YP_002940093.1 CDS Kole_0364 NC_012785.1 382010 383194 R PFAM: Integrase catalytic region; KEGG: bja:bll1898 transposase; Integrase catalytic region complement(382010..383194) Kosmotoga olearia TBF 19.5.1 7968961 YP_002940094.1 CDS Kole_0365 NC_012785.1 383373 383867 D hypothetical protein 383373..383867 Kosmotoga olearia TBF 19.5.1 7968962 YP_002940095.1 CDS Kole_0366 NC_012785.1 383913 384551 R PFAM: MgtC/SapB transporter; KEGG: geo:Geob_2390 MgtC/SapB transporter; MgtC/SapB transporter complement(383913..384551) Kosmotoga olearia TBF 19.5.1 7968963 YP_002940096.1 CDS Kole_0367 NC_012785.1 384638 385825 D PFAM: major facilitator superfamily MFS_1; KEGG: net:Neut_0214 major facilitator transporter; major facilitator superfamily MFS_1 384638..385825 Kosmotoga olearia TBF 19.5.1 7968964 YP_002940097.1 CDS Kole_0368 NC_012785.1 385838 387172 D TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: vch:VC1631 hypothetical protein; MATE efflux family protein 385838..387172 Kosmotoga olearia TBF 19.5.1 7968965 YP_002940098.1 CDS Kole_0369 NC_012785.1 387290 387739 D PFAM: FeoA family protein; KEGG: mgm:Mmc1_1730 FeoA family protein; FeoA family protein 387290..387739 Kosmotoga olearia TBF 19.5.1 7968966 YP_002940099.1 CDS Kole_0370 NC_012785.1 387736 389748 D TIGRFAM: ferrous iron transport protein B; small GTP-binding protein; PFAM: Ferrous iron transport protein B domain protein; GTP-binding protein HSR1-related; nucleoside recognition domain protein; Ferrous iron transport B domain protein; KEGG: dal:Dalk_1642 ferrous iron transport protein B; ferrous iron transport protein B 387736..389748 Kosmotoga olearia TBF 19.5.1 7968967 YP_002940100.1 CDS Kole_0371 NC_012785.1 389745 390128 D hypothetical protein 389745..390128 Kosmotoga olearia TBF 19.5.1 7968968 YP_002940101.1 CDS Kole_0372 NC_012785.1 390211 390837 D PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: dal:Dalk_4458 multi-sensor hybrid histidine kinase; response regulator receiver protein 390211..390837 Kosmotoga olearia TBF 19.5.1 7968969 YP_002940102.1 CDS Kole_0373 NC_012785.1 390838 391290 D PFAM: TrkA-N domain protein; KEGG: mca:MCA2849 potassium transporter peripheral membrane component; TrkA-N domain protein 390838..391290 Kosmotoga olearia TBF 19.5.1 7968970 YP_002940103.1 CDS Kole_0374 NC_012785.1 391287 391949 D PFAM: TrkA-N domain protein; TrkA-C domain protein; KEGG: pla:Plav_3126 potassium transporter peripheral membrane component; TrkA-N domain protein 391287..391949 Kosmotoga olearia TBF 19.5.1 7968971 YP_002940104.1 CDS Kole_0375 NC_012785.1 391950 393458 D PFAM: cation transporter; KEGG: dol:Dole_3217 TrkH family potassium uptake protein; cation transporter 391950..393458 Kosmotoga olearia TBF 19.5.1 7968972 YP_002940105.1 CDS Kole_0376 NC_012785.1 393461 394720 D KEGG: geo:Geob_2622 histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; histidyl-tRNA synthetase 393461..394720 Kosmotoga olearia TBF 19.5.1 7968973 YP_002940106.1 CDS Kole_0377 NC_012785.1 394850 395614 D KEGG: bha:BH1414 hypothetical protein; hypothetical protein 394850..395614 Kosmotoga olearia TBF 19.5.1 7968974 YP_002940107.1 CDS Kole_0378 NC_012785.1 395611 397212 D PFAM: Domain of unknown function DUF1957; glycoside hydrolase family 57; KEGG: ank:AnaeK_1135 domain of unknown function DUF1957; hypothetical protein 395611..397212 Kosmotoga olearia TBF 19.5.1 7968975 YP_002940108.1 CDS Kole_0379 NC_012785.1 397226 397795 D TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: ppd:Ppro_0322 pyruvate/ketoisovalerate oxidoreductase, gamma subunit; pyruvate/ketoisovalerate oxidoreductase, gamma subunit 397226..397795 Kosmotoga olearia TBF 19.5.1 7968976 YP_002940109.1 CDS Kole_0380 NC_012785.1 397795 398091 D TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: ppd:Ppro_0323 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit 397795..398091 Kosmotoga olearia TBF 19.5.1 7968977 YP_002940110.1 CDS Kole_0381 NC_012785.1 398097 399266 D PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: nam:NAMH_0242 pyruvate synthase subunit PorA; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein 398097..399266 Kosmotoga olearia TBF 19.5.1 7968978 YP_002940111.1 CDS Kole_0382 NC_012785.1 399284 400258 D PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: ppd:Ppro_0325 thiamine pyrophosphate binding domain-containing protein; thiamine pyrophosphate protein domain protein TPP-binding 399284..400258 Kosmotoga olearia TBF 19.5.1 7968979 YP_002940112.1 CDS Kole_0383 NC_012785.1 400386 402407 D PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: bha:BH1177 protein secretion (post-translocation chaperonin); PpiC-type peptidyl-prolyl cis-trans isomerase 400386..402407 Kosmotoga olearia TBF 19.5.1 7968980 YP_002940113.1 CDS Kole_0384 NC_012785.1 402618 404282 D KEGG: Phosphoribulokinase / Uridine kinase family protein; Phosphoribulokinase / Uridine kinase family protein 402618..404282 Kosmotoga olearia TBF 19.5.1 7968982 YP_002940114.1 CDS Kole_0385 NC_012785.1 404298 404567 D PFAM: protein of unknown function DUF156; KEGG: sat:SYN_00719 cytoplasmic protein; hypothetical protein 404298..404567 Kosmotoga olearia TBF 19.5.1 7968983 YP_002940115.1 CDS Kole_0386 NC_012785.1 404569 405357 D PFAM: tRNA methyltransferase complex GCD14 subunit; KEGG: dvl:Dvul_0323 protein-L-isoaspartate methyltransferase-like protein; tRNA (adenine-N(1)-)-methyltransferase 404569..405357 Kosmotoga olearia TBF 19.5.1 7968984 YP_002940116.1 CDS Kole_0387 NC_012785.1 405341 406564 D KEGG: mgm:Mmc1_3509 carboxyl-terminal protease; TIGRFAM: carboxyl-terminal protease; PFAM: peptidase S41; PDZ/DHR/GLGF domain protein; SMART: peptidase S41; PDZ/DHR/GLGF domain protein; carboxyl-terminal protease 405341..406564 Kosmotoga olearia TBF 19.5.1 7968985 YP_002940117.1 CDS Kole_0388 NC_012785.1 406571 407224 D hypothetical protein 406571..407224 Kosmotoga olearia TBF 19.5.1 7968986 YP_002940118.1 CDS Kole_0389 NC_012785.1 407228 407716 D hypothetical protein 407228..407716 Kosmotoga olearia TBF 19.5.1 7968987 YP_002940119.1 CDS Kole_0390 NC_012785.1 407713 410115 D KEGG: ppd:Ppro_1642 rRNA methylase; exporter of the RND superfamily protein-like protein 407713..410115 Kosmotoga olearia TBF 19.5.1 7968988 YP_002940120.1 CDS Kole_0391 NC_012785.1 410131 410745 D hypothetical protein 410131..410745 Kosmotoga olearia TBF 19.5.1 7967171 YP_002940121.1 CDS Kole_0392 NC_012785.1 410749 411375 D PFAM: metallophosphoesterase; KEGG: sat:SYN_00526 calcineurin-like phosphoesterase; metallophosphoesterase 410749..411375 Kosmotoga olearia TBF 19.5.1 7967172 YP_002940122.1 CDS Kole_0393 NC_012785.1 411402 412931 D TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; KEGG: gsu:GSU0489 Mg chelatase-related protein; Mg chelatase, subunit ChlI 411402..412931 Kosmotoga olearia TBF 19.5.1 7967173 YP_002940123.1 CDS thiH NC_012785.1 413150 414550 D in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and IscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; in Thermotoga this enzyme has an extra C-terminal domain; thiamine biosynthesis protein ThiH 413150..414550 Kosmotoga olearia TBF 19.5.1 7967174 YP_002940124.1 CDS Kole_0395 NC_012785.1 414510 414785 D hypothetical protein 414510..414785 Kosmotoga olearia TBF 19.5.1 7967175 YP_002940125.1 CDS Kole_0396 NC_012785.1 414775 415866 D PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: sfu:Sfum_0841 biotin synthase; Radical SAM domain protein 414775..415866 Kosmotoga olearia TBF 19.5.1 7967176 YP_002940126.1 CDS Kole_0397 NC_012785.1 415863 417092 D TIGRFAM: small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; Miro domain protein; KEGG: dde:Dde_2276 small GTP-binding protein domain-containing protein; small GTP-binding protein 415863..417092 Kosmotoga olearia TBF 19.5.1 7967177 YP_002940127.1 CDS aspA NC_012785.1 417082 418476 D catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 417082..418476 Kosmotoga olearia TBF 19.5.1 7967178 YP_002940128.1 CDS Kole_0399 NC_012785.1 418536 418943 D KEGG: reu:Reut_A2504 methylglyoxal synthase; TIGRFAM: methylglyoxal synthase; PFAM: MGS domain protein; methylglyoxal synthase 418536..418943 Kosmotoga olearia TBF 19.5.1 7967179 YP_002940129.1 CDS Kole_0400 NC_012785.1 418949 419251 R KEGG: bha:BH0532 hypothetical protein; hypothetical protein complement(418949..419251) Kosmotoga olearia TBF 19.5.1 7967180 YP_002940130.1 CDS Kole_0401 NC_012785.1 419268 421766 R KEGG: ppr:PBPRB1987 hypothetical protein; hypothetical protein complement(419268..421766) Kosmotoga olearia TBF 19.5.1 7967181 YP_002940131.1 CDS Kole_0402 NC_012785.1 421910 423628 R TIGRFAM: oligoendopeptidase, M3 family; PFAM: peptidase M3A and M3B thimet/oligopeptidase F; KEGG: baa:BA_3093 Peptidase_M3, peptidase family M3; oligoendopeptidase, M3 family complement(421910..423628) Kosmotoga olearia TBF 19.5.1 7967182 YP_002940132.1 CDS Kole_0403 NC_012785.1 423801 425363 R PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: glo:Glov_1050 4Fe-4S ferredoxin iron-sulfur binding domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein complement(423801..425363) Kosmotoga olearia TBF 19.5.1 7967183 YP_002940133.1 CDS Kole_0404 NC_012785.1 425938 427125 D PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: bha:BH0799 methionine gamma-lyase; Cystathionine gamma-lyase 425938..427125 Kosmotoga olearia TBF 19.5.1 7967184 YP_002940134.1 CDS Kole_0405 NC_012785.1 427127 428086 D PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: sus:Acid_1558 alcohol dehydrogenase; Alcohol dehydrogenase GroES domain protein 427127..428086 Kosmotoga olearia TBF 19.5.1 7967185 YP_002940135.1 CDS Kole_0406 NC_012785.1 428083 428766 D TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: baa:BA_3891 haloacid dehalogenase-like hydrolase; HAD-superfamily hydrolase, subfamily IA, variant 1 428083..428766 Kosmotoga olearia TBF 19.5.1 7967186 YP_002940136.1 CDS Kole_0407 NC_012785.1 428793 429668 R PFAM: PfkB domain protein; KEGG: smd:Smed_4013 PfkB domain protein; PfkB domain protein complement(428793..429668) Kosmotoga olearia TBF 19.5.1 7967187 YP_002940137.1 CDS Kole_0408 NC_012785.1 429800 432928 D PFAM: acriflavin resistance protein; KEGG: aeh:Mlg_0652 acriflavin resistance protein; acriflavin resistance protein 429800..432928 Kosmotoga olearia TBF 19.5.1 7967188 YP_002940138.1 CDS Kole_0409 NC_012785.1 432950 434200 D PFAM: glycoside hydrolase family 1; KEGG: mxa:MXAN_6303 beta-glucosidase A; Beta-glucosidase 432950..434200 Kosmotoga olearia TBF 19.5.1 7967189 YP_002940139.1 CDS Kole_0410 NC_012785.1 434203 434838 R hypothetical protein complement(434203..434838) Kosmotoga olearia TBF 19.5.1 7967190 YP_002940140.1 CDS Kole_0411 NC_012785.1 434991 436001 D KEGG: cbd:CBUD_0079 hypothetical protein; hypothetical protein 434991..436001 Kosmotoga olearia TBF 19.5.1 7967191 YP_002940141.1 CDS Kole_0412 NC_012785.1 436022 436660 R hypothetical protein complement(436022..436660) Kosmotoga olearia TBF 19.5.1 7967192 YP_002940142.1 CDS Kole_0413 NC_012785.1 436662 437558 R PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: tmz:Tmz1t_0663 FMN-binding domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein complement(436662..437558) Kosmotoga olearia TBF 19.5.1 7967193 YP_002940143.1 CDS Kole_0414 NC_012785.1 437700 438431 D PFAM: protein of unknown function DUF34; KEGG: vsa:VSAL_I0840 hypothetical protein; hypothetical protein 437700..438431 Kosmotoga olearia TBF 19.5.1 7967194 YP_002940144.1 CDS Kole_0415 NC_012785.1 438406 438744 R hypothetical protein complement(438406..438744) Kosmotoga olearia TBF 19.5.1 7967195 YP_002940145.1 CDS Kole_0416 NC_012785.1 443357 444289 R KEGG: shm:Shewmr7_0048 tetratricopeptide domain protein; hypothetical protein complement(443357..444289) Kosmotoga olearia TBF 19.5.1 7967196 YP_002940146.1 CDS Kole_0417 NC_012785.1 444382 445152 R KEGG: scl:sce6765 hypothetical protein; hypothetical protein complement(444382..445152) Kosmotoga olearia TBF 19.5.1 7967197 YP_002940147.1 CDS Kole_0418 NC_012785.1 445302 447494 R PFAM: von Willebrand factor type A; Vault protein inter-alpha-trypsin domain protein; SMART: von Willebrand factor type A; KEGG: sfu:Sfum_3690 vault protein inter-alpha-trypsin domain protein; von Willebrand factor type A complement(445302..447494) Kosmotoga olearia TBF 19.5.1 7967198 YP_002940148.1 CDS Kole_0419 NC_012785.1 447632 449515 R TIGRFAM: M6 family metalloprotease domain protein; PFAM: peptidase M6 immune inhibitor A; KEGG: pin:Ping_2144 peptidase M6, immune inhibitor A; M6 family metalloprotease domain protein complement(447632..449515) Kosmotoga olearia TBF 19.5.1 7967199 YP_002940149.1 CDS Kole_0420 NC_012785.1 449517 450089 R KEGG: ccv:CCV52592_2067 TPR repeat-containing protein; hypothetical protein complement(449517..450089) Kosmotoga olearia TBF 19.5.1 7967200 YP_002940150.1 CDS Kole_0421 NC_012785.1 450350 451426 D PFAM: metallophosphoesterase; KEGG: ilo:IL0120 membrane-associated protein; metallophosphoesterase 450350..451426 Kosmotoga olearia TBF 19.5.1 7967201 YP_002940151.1 CDS Kole_0422 NC_012785.1 451427 452977 R PFAM: Radical SAM domain protein; cobalamin B12-binding domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: gbm:Gbem_3595 radical SAM domain protein; Radical SAM domain protein complement(451427..452977) Kosmotoga olearia TBF 19.5.1 7967202 YP_002940152.1 CDS Kole_0423 NC_012785.1 453169 454032 D TIGRFAM: degV family protein; PFAM: DegV family protein; KEGG: bsu:BSU11110 hypothetical protein; degV family protein 453169..454032 Kosmotoga olearia TBF 19.5.1 7967203 YP_002940153.1 CDS Kole_0424 NC_012785.1 454065 454976 D TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: nis:NIS_0078 cation efflux system protein; cation diffusion facilitator family transporter 454065..454976 Kosmotoga olearia TBF 19.5.1 7967204 YP_002940154.1 CDS Kole_0425 NC_012785.1 455192 455923 D hypothetical protein 455192..455923 Kosmotoga olearia TBF 19.5.1 7967205 YP_002940155.1 CDS Kole_0426 NC_012785.1 455952 456893 D PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: bha:BH0604 methanol dehydrogenase regulatory protein; ATPase associated with various cellular activities AAA_3 455952..456893 Kosmotoga olearia TBF 19.5.1 7967206 YP_002940156.1 CDS Kole_0427 NC_012785.1 456886 458175 D PFAM: protein of unknown function DUF58; KEGG: gur:Gura_0188 hypothetical protein; hypothetical protein 456886..458175 Kosmotoga olearia TBF 19.5.1 7967207 YP_002940157.1 CDS Kole_0428 NC_012785.1 458156 459589 D hypothetical protein 458156..459589 Kosmotoga olearia TBF 19.5.1 7967208 YP_002940158.1 CDS Kole_0431 NC_012785.1 460777 462111 D KEGG: dal:Dalk_0153 Na+/glutamate symporter-like protein; Na+/glutamate symporter-like protein 460777..462111 Kosmotoga olearia TBF 19.5.1 7967211 YP_002940159.1 CDS Kole_0432 NC_012785.1 462189 462692 R hypothetical protein complement(462189..462692) Kosmotoga olearia TBF 19.5.1 7967212 YP_002940160.1 CDS Kole_0433 NC_012785.1 462739 463617 R TIGRFAM: degV family protein; PFAM: DegV family protein; KEGG: baa:BA_3394 DUF194, uncharacterized protein, DegV family COG1307; degV family protein complement(462739..463617) Kosmotoga olearia TBF 19.5.1 7967213 YP_002940161.1 CDS Kole_0434 NC_012785.1 463782 464303 R PFAM: Chromate transporter; KEGG: pin:Ping_2327 chromate transporter, chromate ion transporter (CHR) family protein; Chromate transporter complement(463782..464303) Kosmotoga olearia TBF 19.5.1 7967214 YP_002940162.1 CDS Kole_0435 NC_012785.1 464300 464830 R PFAM: Chromate transporter; KEGG: vei:Veis_3786 chromate transporter; Chromate transporter complement(464300..464830) Kosmotoga olearia TBF 19.5.1 7967215 YP_002940163.1 CDS Kole_0436 NC_012785.1 464913 465527 D hypothetical protein 464913..465527 Kosmotoga olearia TBF 19.5.1 7967216 YP_002940164.1 CDS Kole_0437 NC_012785.1 465520 466077 D hypothetical protein 465520..466077 Kosmotoga olearia TBF 19.5.1 7967217 YP_002940165.1 CDS Kole_0438 NC_012785.1 466077 466793 D PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: vha:VIBHAR_02834 hypothetical protein; ABC transporter 466077..466793 Kosmotoga olearia TBF 19.5.1 7967218 YP_002940166.1 CDS Kole_0439 NC_012785.1 466800 469826 D PFAM: protein of unknown function DUF214; KEGG: gbm:Gbem_2168 protein of unknown function DUF214; hypothetical protein 466800..469826 Kosmotoga olearia TBF 19.5.1 7967219 YP_002940167.1 CDS Kole_0440 NC_012785.1 469863 471008 D PFAM: response regulator receiver; Stage II sporulation E family protein; SMART: response regulator receiver; protein phosphatase 2C domain protein; KEGG: sat:SYN_00230 response regulator receiver domain-containing protein; response regulator receiver modulated serine phosphatase 469863..471008 Kosmotoga olearia TBF 19.5.1 7967220 YP_002940168.1 CDS Kole_0441 NC_012785.1 471042 471401 D PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: esa:ESA_01838 hypothetical protein; anti-sigma-factor antagonist 471042..471401 Kosmotoga olearia TBF 19.5.1 7967221 YP_002940169.1 CDS Kole_0442 NC_012785.1 471394 471705 D PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: bha:BH1536 anti-sigma F factor antagonist (stage II sporulation protein AA); anti-sigma-factor antagonist 471394..471705 Kosmotoga olearia TBF 19.5.1 7967222 YP_002940170.1 CDS Kole_0443 NC_012785.1 471692 472096 D KEGG: sfu:Sfum_4032 anti-sigma regulatory factor, serine/threonine protein kinase; anti-sigma regulatory factor, serine/threonine protein kinase 471692..472096 Kosmotoga olearia TBF 19.5.1 7967223 YP_002940171.1 CDS Kole_0444 NC_012785.1 472079 474955 R PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: response regulator receiver; histidine kinase A domain protein; ATP-binding region ATPase domain protein; KEGG: nis:NIS_1346 two-component sensor histidine kinase/response regulator; Hpt sensor hybrid histidine kinase complement(472079..474955) Kosmotoga olearia TBF 19.5.1 7967224 YP_002940172.1 CDS Kole_0445 NC_012785.1 475175 475378 D hypothetical protein 475175..475378 Kosmotoga olearia TBF 19.5.1 7967225 YP_002940173.1 CDS Kole_0446 NC_012785.1 475543 476067 D TIGRFAM: ATP/cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; KEGG: dal:Dalk_4989 ATP/cobalamin adenosyltransferase; ATP/cobalamin adenosyltransferase 475543..476067 Kosmotoga olearia TBF 19.5.1 7967226 YP_002940174.1 CDS Kole_0447 NC_012785.1 476113 476748 R hypothetical protein complement(476113..476748) Kosmotoga olearia TBF 19.5.1 7967227 YP_002940175.1 CDS Kole_0448 NC_012785.1 476796 478820 R catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism; urocanate hydratase complement(476796..478820) Kosmotoga olearia TBF 19.5.1 7967228 YP_002940176.1 CDS Kole_0449 NC_012785.1 479181 479810 D PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: gur:Gura_2115 integral membrane sensor signal transduction histidine kinase; extracellular solute-binding protein family 3 479181..479810 Kosmotoga olearia TBF 19.5.1 7967229 YP_002940177.1 CDS Kole_0450 NC_012785.1 479824 480426 R PFAM: transposase IS4 family protein; KEGG: dol:Dole_3091 transposase IS4 family protein; transposase IS4 family protein complement(479824..480426) Kosmotoga olearia TBF 19.5.1 7967230 YP_002940178.1 CDS Kole_0451 NC_012785.1 480410 480790 R hypothetical protein complement(480410..480790) Kosmotoga olearia TBF 19.5.1 7967231 YP_002940179.1 CDS Kole_0452 NC_012785.1 480827 483121 D KEGG: gur:Gura_2803 metal dependent phosphohydrolase; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; GAF domain protein; metal-dependent phosphohydrolase HD sub domain; PAS fold-4 domain protein; SMART: GGDEF domain containing protein; metal-dependent phosphohydrolase HD region; GAF domain protein; diguanylate cyclase and metal dependent phosphohydrolase 480827..483121 Kosmotoga olearia TBF 19.5.1 7967232 YP_002940180.1 CDS Kole_0453 NC_012785.1 483133 484155 D KEGG: gsu:GSU3009 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; TIGRFAM: nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase; PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase 483133..484155 Kosmotoga olearia TBF 19.5.1 7967233 YP_002940181.1 CDS Kole_0454 NC_012785.1 484152 484640 D PFAM: cobalbumin biosynthesis protein; KEGG: hne:HNE_1521 cobinamide kinase / cobinamide phosphate guanyltransferase; Adenosylcobinamide-phosphate guanylyltransferase 484152..484640 Kosmotoga olearia TBF 19.5.1 7967234 YP_002940182.1 CDS Kole_0455 NC_012785.1 484637 485236 D KEGG: dvl:Dvul_2481 hypothetical protein; hypothetical protein 484637..485236 Kosmotoga olearia TBF 19.5.1 7967235 YP_002940183.1 CDS Kole_0456 NC_012785.1 485226 485921 D PFAM: cobalamin-5-phosphate synthase CobS; KEGG: smd:Smed_1604 cobalamin synthase; cobalamin-5-phosphate synthase CobS 485226..485921 Kosmotoga olearia TBF 19.5.1 7967236 YP_002940184.1 CDS Kole_0457 NC_012785.1 486047 486481 D TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; KEGG: ecn:Ecaj_0411 BadM/Rrf2 family transcriptional regulator; BadM/Rrf2 family transcriptional regulator 486047..486481 Kosmotoga olearia TBF 19.5.1 7967237 YP_002940185.1 CDS Kole_0458 NC_012785.1 486478 486939 D KEGG: cbc:CbuK_1370 DNA polymerase X family; DNA polymerase IV (family X)-like protein 486478..486939 Kosmotoga olearia TBF 19.5.1 7967238 YP_002940186.1 CDS Kole_0459 NC_012785.1 486974 488191 D PFAM: major facilitator superfamily MFS_1; KEGG: dat:HRM2_41620 permease of the major facilitator superfamily; major facilitator superfamily MFS_1 486974..488191 Kosmotoga olearia TBF 19.5.1 7967239 YP_002940187.1 CDS Kole_0460 NC_012785.1 488211 489335 D PFAM: Nucleotidyl transferase; transferase hexapeptide repeat containing protein; KEGG: har:HEAR0727 mannose-1-phosphate guanyltransferase; Nucleotidyl transferase 488211..489335 Kosmotoga olearia TBF 19.5.1 7967240 YP_002940188.1 CDS Kole_0461 NC_012785.1 489398 491890 R PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: cja:CJA_3247 alpha-amylase, , amy13H; alpha amylase catalytic region complement(489398..491890) Kosmotoga olearia TBF 19.5.1 7967241 YP_002940189.1 CDS Kole_0462 NC_012785.1 492324 493262 R PFAM: inner-membrane translocator; KEGG: dvm:DvMF_3028 inner-membrane translocator; inner-membrane translocator complement(492324..493262) Kosmotoga olearia TBF 19.5.1 7967242 YP_002940190.1 CDS Kole_0463 NC_012785.1 493259 494371 R PFAM: inner-membrane translocator; KEGG: dde:Dde_0138 branched-chain amino acid ABC transporter, permease protein; inner-membrane translocator complement(493259..494371) Kosmotoga olearia TBF 19.5.1 7967243 YP_002940191.1 CDS Kole_0464 NC_012785.1 494368 495900 R PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: baa:BA_4398 simple sugar transport system ATP-binding protein; ABC transporter complement(494368..495900) Kosmotoga olearia TBF 19.5.1 7967244 YP_002940192.1 CDS Kole_0465 NC_012785.1 495983 497041 R PFAM: basic membrane lipoprotein; KEGG: dps:DP0677 hypothetical protein; basic membrane lipoprotein complement(495983..497041) Kosmotoga olearia TBF 19.5.1 7967245 YP_002940193.1 CDS Kole_0466 NC_012785.1 497309 498172 D PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bha:BH1003 ABC transporter ATP-binding protein; ABC transporter 497309..498172 Kosmotoga olearia TBF 19.5.1 7967246 YP_002940194.1 CDS Kole_0467 NC_012785.1 498169 498972 D KEGG: sde:Sde_3735 heavy metal efflux pump CzcA; hypothetical protein 498169..498972 Kosmotoga olearia TBF 19.5.1 7967247 YP_002940195.1 CDS Kole_0468 NC_012785.1 499664 501163 D PFAM: WD-40 repeat protein; SMART: WD-40 repeat protein; KEGG: hypothetical protein; WD-40 repeat protein 499664..501163 Kosmotoga olearia TBF 19.5.1 7967248 YP_002940196.1 CDS Kole_0469 NC_012785.1 501181 501756 D hypothetical protein 501181..501756 Kosmotoga olearia TBF 19.5.1 7967249 YP_002940197.1 CDS Kole_0470 NC_012785.1 501757 502971 D KEGG: hch:HCH_03464 methyl-accepting chemotaxis protein; hypothetical protein 501757..502971 Kosmotoga olearia TBF 19.5.1 7967250 YP_002940198.1 CDS Kole_0471 NC_012785.1 502991 505141 D PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase ; helicase domain protein; KEGG: acp:A2cp1_1160 DEAD/DEAH box helicase domain protein; DEAD/DEAH box helicase domain protein 502991..505141 Kosmotoga olearia TBF 19.5.1 7967251 YP_002940199.1 CDS Kole_0472 NC_012785.1 505528 506094 D hypothetical protein 505528..506094 Kosmotoga olearia TBF 19.5.1 7967333 YP_002940200.1 CDS Kole_0473 NC_012785.1 506142 506522 D hypothetical protein 506142..506522 Kosmotoga olearia TBF 19.5.1 7967334 YP_002940201.1 CDS Kole_0474 NC_012785.1 506549 509275 D hypothetical protein 506549..509275 Kosmotoga olearia TBF 19.5.1 7967335 YP_002940202.1 CDS Kole_0475 NC_012785.1 509432 510310 D PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: tgr:Tgr7_2207 radical SAM domain protein; Radical SAM domain protein 509432..510310 Kosmotoga olearia TBF 19.5.1 7967336 YP_002940203.1 CDS Kole_0476 NC_012785.1 510307 511260 D PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: tgr:Tgr7_2204 radical SAM domain protein; Radical SAM domain protein 510307..511260 Kosmotoga olearia TBF 19.5.1 7967337 YP_002940204.1 CDS Kole_0477 NC_012785.1 511281 512123 D PFAM: biotin/lipoate A/B protein ligase; KEGG: bha:BH2812 lipoate protein ligase; biotin/lipoate A/B protein ligase 511281..512123 Kosmotoga olearia TBF 19.5.1 7967338 YP_002940205.1 CDS Kole_0478 NC_012785.1 512310 514913 D PFAM: glycoside hydrolase family 38; glycosyl hydrolase 38 domain protein; KEGG: efe:EFER_2372 alpha-mannosidase; glycoside hydrolase family 38 512310..514913 Kosmotoga olearia TBF 19.5.1 7967339 YP_002940206.1 CDS Kole_0479 NC_012785.1 514970 516238 D PFAM: extracellular solute-binding protein family 1; KEGG: bha:BH1864 hypothetical protein; extracellular solute-binding protein family 1 514970..516238 Kosmotoga olearia TBF 19.5.1 7967340 YP_002940207.1 CDS Kole_0480 NC_012785.1 516452 517354 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bha:BH1865 sugar transport system (permease) (binding protein dependent transporter); binding-protein-dependent transport systems inner membrane component 516452..517354 Kosmotoga olearia TBF 19.5.1 7967341 YP_002940208.1 CDS Kole_0481 NC_012785.1 517373 518215 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SM_b20969 sugar uptake ABC transporter permease protein; binding-protein-dependent transport systems inner membrane component 517373..518215 Kosmotoga olearia TBF 19.5.1 7967342 YP_002940209.1 CDS Kole_0482 NC_012785.1 518229 520376 D KEGG: Gm50; gene model 50, (NCBI); hypothetical protein 518229..520376 Kosmotoga olearia TBF 19.5.1 7967343 YP_002940210.1 CDS Kole_0483 NC_012785.1 520393 522639 D TIGRFAM: alpha-1,2-mannosidase; PFAM: glycosyl hydrolase 92; KEGG: shm:Shewmr7_3384 alpha-1,2-mannosidase; alpha-1,2-mannosidase 520393..522639 Kosmotoga olearia TBF 19.5.1 7967344 YP_002940211.1 CDS Kole_0484 NC_012785.1 522656 523711 D PFAM: regulatory protein GntR HTH; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein GntR HTH; KEGG: sus:Acid_4349 GntR family transcriptional regulator; GntR family transcriptional regulator 522656..523711 Kosmotoga olearia TBF 19.5.1 7967345 YP_002940212.1 CDS Kole_0485 NC_012785.1 524065 525126 R PFAM: 2-nitropropane dioxygenase NPD; KEGG: dde:Dde_1586 2-nitropropane dioxygenase family oxidoreductase; 2-nitropropane dioxygenase NPD complement(524065..525126) Kosmotoga olearia TBF 19.5.1 7967346 YP_002940213.1 CDS Kole_0486 NC_012785.1 526135 527256 D PFAM: Malate/L-lactate dehydrogenase; KEGG: malate dehydrogenase ; K00025 malate dehydrogenase; Malate/L-lactate dehydrogenase 526135..527256 Kosmotoga olearia TBF 19.5.1 7967347 YP_002940214.1 CDS Kole_0487 NC_012785.1 527290 528444 D PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: bar:GBAA4848 malate dehydrogenase; Malate dehydrogenase (oxaloacetate-decarboxylating) 527290..528444 Kosmotoga olearia TBF 19.5.1 7967348 YP_002940215.1 CDS Kole_0488 NC_012785.1 528463 529245 D TIGRFAM: CRISPR-associated protein Cas6; PFAM: protein of unknown function DUF57; CRISPR-associated protein Cas6 528463..529245 Kosmotoga olearia TBF 19.5.1 7967349 YP_002940216.1 CDS Kole_0489 NC_012785.1 529285 529443 D hypothetical protein 529285..529443 Kosmotoga olearia TBF 19.5.1 7967350 YP_002940217.1 CDS Kole_0490 NC_012785.1 530970 532361 R PFAM: ATPase; DUF234 DEXX-box ATPase; KEGG: sat:SYN_01513 ATPase; ATPase complement(530970..532361) Kosmotoga olearia TBF 19.5.1 7967351 YP_002940218.1 CDS Kole_0491 NC_012785.1 532699 533991 R PFAM: transposase IS116/IS110/IS902 family protein; transposase IS111A/IS1328/IS1533; KEGG: bxe:Bxe_B2763 transposase IS110; transposase IS116/IS110/IS902 family protein complement(532699..533991) Kosmotoga olearia TBF 19.5.1 7967352 YP_002940219.1 CDS Kole_0492 NC_012785.1 534222 534779 R hypothetical protein complement(534222..534779) Kosmotoga olearia TBF 19.5.1 7967353 YP_002940220.1 CDS Kole_0493 NC_012785.1 534776 539263 R PFAM: alpha-2-macroglobulin domain protein; alpha-2-macroglobulin; KEGG: ppd:Ppro_1300 alpha-2-macroglobulin domain-containing protein; alpha-2-macroglobulin domain protein complement(534776..539263) Kosmotoga olearia TBF 19.5.1 7967354 YP_002940221.1 CDS Kole_0494 NC_012785.1 539260 540225 R PFAM: protein of unknown function DUF1175; KEGG: ecz:ECS88_2377 hypothetical protein; hypothetical protein complement(539260..540225) Kosmotoga olearia TBF 19.5.1 7967355 YP_002940222.1 CDS Kole_0495 NC_012785.1 540544 541716 R KEGG: bha:BH1812 hypothetical protein; acetyltransferase complement(540544..541716) Kosmotoga olearia TBF 19.5.1 7967356 YP_002940223.1 CDS Kole_0496 NC_012785.1 541869 543116 R KEGG: baa:BA_3344 hypothetical protein; hypothetical protein complement(541869..543116) Kosmotoga olearia TBF 19.5.1 7967357 YP_002940224.1 CDS Kole_0497 NC_012785.1 543113 544420 R hypothetical protein complement(543113..544420) Kosmotoga olearia TBF 19.5.1 7967358 YP_002940225.1 CDS Kole_0498 NC_012785.1 544438 545610 R PFAM: GCN5-related N-acetyltransferase; KEGG: bha:BH1812 hypothetical protein; GCN5-related N-acetyltransferase complement(544438..545610) Kosmotoga olearia TBF 19.5.1 7967359 YP_002940226.1 CDS Kole_0500 NC_012785.1 547939 548169 R hypothetical protein complement(547939..548169) Kosmotoga olearia TBF 19.5.1 7967361 YP_002940227.1 CDS Kole_0501 NC_012785.1 548327 548440 R hypothetical protein complement(548327..548440) Kosmotoga olearia TBF 19.5.1 7967362 YP_002940228.1 CDS Kole_0502 NC_012785.1 549123 550379 R PFAM: major facilitator superfamily MFS_1; KEGG: bar:GBAA2664 permease; major facilitator superfamily MFS_1 complement(549123..550379) Kosmotoga olearia TBF 19.5.1 7967363 YP_002940229.1 CDS Kole_0503 NC_012785.1 550647 551249 R PFAM: transposase IS4 family protein; KEGG: dol:Dole_3091 transposase IS4 family protein; transposase IS4 family protein complement(550647..551249) Kosmotoga olearia TBF 19.5.1 7967364 YP_002940230.1 CDS Kole_0504 NC_012785.1 551233 551613 R hypothetical protein complement(551233..551613) Kosmotoga olearia TBF 19.5.1 7967365 YP_002940231.1 CDS gldA NC_012785.1 551927 553021 D forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase 551927..553021 Kosmotoga olearia TBF 19.5.1 7967366 YP_002940232.1 CDS Kole_0506 NC_012785.1 553128 553424 D hypothetical protein 553128..553424 Kosmotoga olearia TBF 19.5.1 7967367 YP_002940233.1 CDS Kole_0507 NC_012785.1 553543 553725 D KEGG: dde:Dde_0885 hypothetical protein; hypothetical protein 553543..553725 Kosmotoga olearia TBF 19.5.1 7967368 YP_002940234.1 CDS Kole_0508 NC_012785.1 553966 554940 D KEGG: scl:sce5021 hydrolase; Poly(3-hydroxybutyrate) depolymerase-like protein 553966..554940 Kosmotoga olearia TBF 19.5.1 7967369 YP_002940235.1 CDS Kole_0509 NC_012785.1 554966 555658 R TIGRFAM: aspartate racemase; PFAM: Asp/Glu/hydantoin racemase; KEGG: pol:Bpro_4755 aspartate racemase; aspartate racemase complement(554966..555658) Kosmotoga olearia TBF 19.5.1 7967370 YP_002940236.1 CDS Kole_0510 NC_012785.1 555708 556994 R TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: gur:Gura_3277 FolC bifunctional protein; FolC bifunctional protein complement(555708..556994) Kosmotoga olearia TBF 19.5.1 7967371 YP_002940237.1 CDS Kole_0511 NC_012785.1 556984 558450 R TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; KEGG: bsu:BSU15180 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; UDP-N-acetylmuramyl-tripeptide synthetase complement(556984..558450) Kosmotoga olearia TBF 19.5.1 7967372 YP_002940238.1 CDS Kole_0512 NC_012785.1 558465 559871 R TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; KEGG: sat:SYN_01742 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl- D-alanyl ligase; UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase complement(558465..559871) Kosmotoga olearia TBF 19.5.1 7967373 YP_002940239.1 CDS Kole_0513 NC_012785.1 560338 564183 R KEGG: DNA-directed RNA polymerase, omega subunit family protein; hypothetical protein complement(560338..564183) Kosmotoga olearia TBF 19.5.1 7967374 YP_002940240.1 CDS Kole_0514 NC_012785.1 564347 565486 R PFAM: nucleoside recognition domain protein; KEGG: aha:AHA_3839 transporter gate domain-containing protein; nucleoside recognition domain protein complement(564347..565486) Kosmotoga olearia TBF 19.5.1 7967375 YP_002940241.1 CDS Kole_0515 NC_012785.1 565861 566199 D KEGG: dal:Dalk_3208 hypothetical protein; hypothetical protein 565861..566199 Kosmotoga olearia TBF 19.5.1 7967376 YP_002940242.1 CDS Kole_0516 NC_012785.1 566247 566654 D hypothetical protein 566247..566654 Kosmotoga olearia TBF 19.5.1 7967377 YP_002940243.1 CDS Kole_0517 NC_012785.1 566661 567005 D KEGG: sml:Smlt1976 hypothetical protein; hypothetical protein 566661..567005 Kosmotoga olearia TBF 19.5.1 7967378 YP_002940244.1 CDS Kole_0518 NC_012785.1 567135 568367 D PFAM: LemA family protein; KEGG: mmr:Mmar10_1566 LemA family protein; LemA family protein 567135..568367 Kosmotoga olearia TBF 19.5.1 7967379 YP_002940245.1 CDS Kole_0519 NC_012785.1 568414 569046 D PFAM: Phosphoglycerate mutase; KEGG: baa:BA_2572 PGAM, phosphoglycerate mutase family; Phosphoglycerate mutase 568414..569046 Kosmotoga olearia TBF 19.5.1 7967380 YP_002940246.1 CDS Kole_0520 NC_012785.1 569121 569567 R PFAM: NUDIX hydrolase; KEGG: sfv:SFV_2366 regulator; NUDIX hydrolase complement(569121..569567) Kosmotoga olearia TBF 19.5.1 7967381 YP_002940247.1 CDS Kole_0522 NC_012785.1 571691 573520 R PFAM: glycoside hydrolase clan GH-D; KEGG: hypothetical protein; glycoside hydrolase clan GH-D complement(571691..573520) Kosmotoga olearia TBF 19.5.1 7967383 YP_002940248.1 CDS Kole_0523 NC_012785.1 573951 574328 D PFAM: transposase IS3/IS911 family protein; KEGG: net:Neut_1719 transposase IS3/IS911 family protein; transposase IS3/IS911 family protein 573951..574328 Kosmotoga olearia TBF 19.5.1 7967384 YP_002940249.1 CDS Kole_0524 NC_012785.1 574355 574702 D hypothetical protein 574355..574702 Kosmotoga olearia TBF 19.5.1 7967385 YP_002940250.1 CDS Kole_0525 NC_012785.1 574791 575894 D PFAM: Integrase catalytic region; KEGG: sfu:Sfum_2833 integrase, catalytic region; Integrase catalytic region 574791..575894 Kosmotoga olearia TBF 19.5.1 7967386 YP_002940251.1 CDS Kole_0526 NC_012785.1 575891 576688 D PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: sfu:Sfum_2832 IstB domain protein ATP-binding protein; IstB domain protein ATP-binding protein 575891..576688 Kosmotoga olearia TBF 19.5.1 7967387 YP_002940252.1 CDS Kole_0528 NC_012785.1 577626 579743 R KEGG: pca:Pcar_1474 hypothetical protein; hypothetical protein complement(577626..579743) Kosmotoga olearia TBF 19.5.1 7967389 YP_002940253.1 CDS Kole_0529 NC_012785.1 580272 580925 R TIGRFAM: anaerobic ribonucleoside-triphosphate reductase activating protein; PFAM: Radical SAM domain protein; KEGG: dat:HRM2_04840 PflA; anaerobic ribonucleoside-triphosphate reductase activating protein complement(580272..580925) Kosmotoga olearia TBF 19.5.1 7967390 YP_002940254.1 CDS Kole_0530 NC_012785.1 580843 582996 R Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase complement(580843..582996) Kosmotoga olearia TBF 19.5.1 7967391 YP_002940255.1 CDS Kole_0531 NC_012785.1 583172 583714 R KEGG: rce:RC1_0992 exonuclease, TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; DNA polymerase III, epsilon subunit complement(583172..583714) Kosmotoga olearia TBF 19.5.1 7967392 YP_002940256.1 CDS Kole_0532 NC_012785.1 583716 584858 R KEGG: bha:BH2668 hippurate hydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; amidohydrolase complement(583716..584858) Kosmotoga olearia TBF 19.5.1 7967393 YP_002940257.1 CDS Kole_0533 NC_012785.1 584959 585294 D hypothetical protein 584959..585294 Kosmotoga olearia TBF 19.5.1 7967394 YP_002940258.1 CDS Kole_0534 NC_012785.1 585320 586780 D TIGRFAM: glycerol kinase; PFAM: carbohydrate kinase FGGY; KEGG: pfo:Pfl01_4532 glycerol kinase; glycerol kinase 585320..586780 Kosmotoga olearia TBF 19.5.1 7967395 YP_002940259.1 CDS Kole_0535 NC_012785.1 586738 587247 D PFAM: protein of unknown function UPF0079; KEGG: rsq:Rsph17025_2955 hypothetical protein; hypothetical protein 586738..587247 Kosmotoga olearia TBF 19.5.1 7967396 YP_002940260.1 CDS Kole_0536 NC_012785.1 587247 589622 D KEGG: rsh:Rsph17029_1493 ATP-dependent protease La; TIGRFAM: ATP-dependent protease La; PFAM: peptidase S16 lon domain protein; AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; SMART: peptidase S16 lon domain protein; AAA ATPase; ATP-dependent protease La 587247..589622 Kosmotoga olearia TBF 19.5.1 7967397 YP_002940261.1 CDS engB NC_012785.1 589603 590175 D binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 589603..590175 Kosmotoga olearia TBF 19.5.1 7967398 YP_002940262.1 CDS Kole_0538 NC_012785.1 590563 592044 R KEGG: tcx:Tcr_1150 diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; diguanylate cyclase complement(590563..592044) Kosmotoga olearia TBF 19.5.1 7967399 YP_002940263.1 CDS Kole_0539 NC_012785.1 592387 593037 D PFAM: protein of unknown function DUF47; KEGG: lpn:lpg0584 phosphate transport regulator; hypothetical protein 592387..593037 Kosmotoga olearia TBF 19.5.1 7967400 YP_002940264.1 CDS Kole_0540 NC_012785.1 593073 593681 R PFAM: phosphate transporter; KEGG: sfr:Sfri_3885 phosphate transporter; phosphate transporter complement(593073..593681) Kosmotoga olearia TBF 19.5.1 7967401 YP_002940265.1 CDS Kole_0541 NC_012785.1 593756 594358 R PFAM: transposase IS4 family protein; KEGG: dol:Dole_3091 transposase IS4 family protein; transposase IS4 family protein complement(593756..594358) Kosmotoga olearia TBF 19.5.1 7967402 YP_002940266.1 CDS Kole_0542 NC_012785.1 594342 594722 R hypothetical protein complement(594342..594722) Kosmotoga olearia TBF 19.5.1 7967403 YP_002940267.1 CDS Kole_0543 NC_012785.1 594807 595091 R KEGG: sse:Ssed_0370 phosphate transporter; phosphate transporter complement(594807..595091) Kosmotoga olearia TBF 19.5.1 7967404 YP_002940268.1 CDS Kole_0544 NC_012785.1 595343 595816 D PFAM: NUDIX hydrolase; KEGG: vpa:VP1487 MutT/NUDIX family protein; NUDIX hydrolase 595343..595816 Kosmotoga olearia TBF 19.5.1 7967405 YP_002940269.1 CDS Kole_0545 NC_012785.1 595944 596480 D TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: baa:BA_0277 ribosomal_S30, Sigma 54 modulation protein / S30EA ribosomal protein; sigma 54 modulation protein/ribosomal protein S30EA 595944..596480 Kosmotoga olearia TBF 19.5.1 7967406 YP_002940270.1 CDS Kole_0546 NC_012785.1 596551 597996 D KEGG: gme:Gmet_3192 ribonuclease G; TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA binding S1 domain protein; SMART: RNA binding S1 domain protein; ribonuclease, Rne/Rng family 596551..597996 Kosmotoga olearia TBF 19.5.1 7967407 YP_002940271.1 CDS Kole_0547 NC_012785.1 598761 599039 D PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: pca:Pcar_0183 transcriptional regulator; ArsR family transcriptional regulator 598761..599039 Kosmotoga olearia TBF 19.5.1 7967410 YP_002940272.1 CDS Kole_0548 NC_012785.1 599111 600211 D PFAM: permease; KEGG: dat:HRM2_48210 permease; permease 599111..600211 Kosmotoga olearia TBF 19.5.1 7967411 YP_002940273.1 CDS Kole_0549 NC_012785.1 600229 600462 D TIGRFAM: redox-active disulfide protein 2; PFAM: glutaredoxin; KEGG: sfu:Sfum_3598 redox-active disulfide protein 2; redox-active disulfide protein 2 600229..600462 Kosmotoga olearia TBF 19.5.1 7967412 YP_002940274.1 CDS Kole_0550 NC_012785.1 600817 602187 R PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: gsu:GSU0452 sensor histidine kinase; histidine kinase complement(600817..602187) Kosmotoga olearia TBF 19.5.1 7967413 YP_002940275.1 CDS Kole_0551 NC_012785.1 602197 602898 R PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: gsu:GSU0451 DNA-binding response regulator; two component transcriptional regulator, winged helix family complement(602197..602898) Kosmotoga olearia TBF 19.5.1 7968143 YP_002940276.1 CDS Kole_0552 NC_012785.1 602976 603497 R PFAM: Propeptide PepSY amd peptidase M4; KEGG: bha:BH0375 hypothetical protein; Propeptide PepSY amd peptidase M4 complement(602976..603497) Kosmotoga olearia TBF 19.5.1 7968746 YP_002940277.1 CDS Kole_0553 NC_012785.1 603881 605266 D PFAM: peptidase U62 modulator of DNA gyrase; KEGG: ppr:PBPRB1170 TldD protein; peptidase U62 modulator of DNA gyrase 603881..605266 Kosmotoga olearia TBF 19.5.1 7968747 YP_002940278.1 CDS Kole_0554 NC_012785.1 605263 606633 D PFAM: peptidase U62 modulator of DNA gyrase; KEGG: gme:Gmet_0947 peptidase U62, modulator of DNA gyrase; peptidase U62 modulator of DNA gyrase 605263..606633 Kosmotoga olearia TBF 19.5.1 7968748 YP_002940279.1 CDS Kole_0555 NC_012785.1 606719 607060 R KEGG: nam:NAMH_1055 hydrogenase expression/synthesis, HypA; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)-like protein complement(606719..607060) Kosmotoga olearia TBF 19.5.1 7968749 YP_002940280.1 CDS Kole_0556 NC_012785.1 607109 608089 R TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein domain protein; AIR synthase related protein; KEGG: wsu:WS0795 hydrogenase expression/formation protein; hydrogenase expression/formation protein HypE complement(607109..608089) Kosmotoga olearia TBF 19.5.1 7968750 YP_002940281.1 CDS Kole_0557 NC_012785.1 608094 609110 R PFAM: hydrogenase formation HypD protein; KEGG: sfu:Sfum_4014 hydrogenase expression/formation protein HypD; hydrogenase formation HypD protein complement(608094..609110) Kosmotoga olearia TBF 19.5.1 7968751 YP_002940282.1 CDS Kole_0558 NC_012785.1 609100 609327 R TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: dat:HRM2_11590 HypC; hydrogenase assembly chaperone hypC/hupF complement(609100..609327) Kosmotoga olearia TBF 19.5.1 7968752 YP_002940283.1 CDS Kole_0559 NC_012785.1 609324 611567 R TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: SUA5/yciO/yrdC domain; acylphosphatase; zinc finger HypF domain protein; KEGG: gsu:GSU0306 hydrogenase maturation protein HypF; (NiFe) hydrogenase maturation protein HypF complement(609324..611567) Kosmotoga olearia TBF 19.5.1 7968753 YP_002940284.1 CDS Kole_0560 NC_012785.1 611555 612004 R TIGRFAM: hydrogenase maturation protease; KEGG: rru:Rru_A0322 peptidase M52, hydrogen uptake protein; hydrogenase maturation protease complement(611555..612004) Kosmotoga olearia TBF 19.5.1 7968754 YP_002940285.1 CDS Kole_0561 NC_012785.1 612021 612629 R PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: rru:Rru_A0318 4Fe-4S ferredoxin, iron-sulfur binding; 4Fe-4S ferredoxin iron-sulfur binding domain protein complement(612021..612629) Kosmotoga olearia TBF 19.5.1 7968755 YP_002940286.1 CDS Kole_0562 NC_012785.1 612610 612969 R TIGRFAM: monovalent cation/proton antiporter, MnhG/PhaG subunit; PFAM: Na+/H+ antiporter subunit; KEGG: mgm:Mmc1_2214 monovalent cation/H+ antiporter subunit G; monovalent cation/proton antiporter, MnhG/PhaG subunit complement(612610..612969) Kosmotoga olearia TBF 19.5.1 7968756 YP_002940287.1 CDS Kole_0563 NC_012785.1 612962 613300 R PFAM: multiple resistance and pH regulation protein F; KEGG: atc:AGR_C_1665 cation efflux system protein; multiple resistance and pH regulation protein F complement(612962..613300) Kosmotoga olearia TBF 19.5.1 7968757 YP_002940288.1 CDS Kole_0564 NC_012785.1 613297 613800 R PFAM: cation antiporter; KEGG: mgm:Mmc1_2216 membrane bound protein complex subunit MbxA; cation antiporter complement(613297..613800) Kosmotoga olearia TBF 19.5.1 7968758 YP_002940289.1 CDS Kole_0565 NC_012785.1 613797 615275 R PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: ppd:Ppro_0589 NADH dehydrogenase (quinone); NADH/Ubiquinone/plastoquinone (complex I) complement(613797..615275) Kosmotoga olearia TBF 19.5.1 7968759 YP_002940290.1 CDS Kole_0566 NC_012785.1 615272 615616 R PFAM: NADH-ubiquinone oxidoreductase chain 4L; KEGG: mgm:Mmc1_2211 membrane bound protein complex subunit MbxG; NADH-ubiquinone oxidoreductase chain 4L complement(615272..615616) Kosmotoga olearia TBF 19.5.1 7968760 YP_002940291.1 CDS Kole_0568 NC_012785.1 618398 619606 R PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; KEGG: ppd:Ppro_3524 NADH dehydrogenase (ubiquinone); NADH-ubiquinone oxidoreductase chain 49kDa complement(618398..619606) Kosmotoga olearia TBF 19.5.1 7968762 YP_002940292.1 CDS Kole_0569 NC_012785.1 619599 620039 R PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit; KEGG: sus:Acid_0110 NADH (or F420H2) dehydrogenase, subunit C; NADH dehydrogenase (ubiquinone) 30 kDa subunit complement(619599..620039) Kosmotoga olearia TBF 19.5.1 7968763 YP_002940293.1 CDS Kole_0570 NC_012785.1 620041 620454 R PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: rru:Rru_A0321 NADH dehydrogenase (ubiquinone), 20 kDa subunit; NADH ubiquinone oxidoreductase 20 kDa subunit complement(620041..620454) Kosmotoga olearia TBF 19.5.1 7968764 YP_002940294.1 CDS Kole_0571 NC_012785.1 620457 621368 R PFAM: respiratory-chain NADH dehydrogenase subunit 1; KEGG: ppd:Ppro_3523 respiratory-chain NADH dehydrogenase, subunit 1; respiratory-chain NADH dehydrogenase subunit 1 complement(620457..621368) Kosmotoga olearia TBF 19.5.1 7968765 YP_002940295.1 CDS Kole_0572 NC_012785.1 621365 621865 R PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dde:Dde_2085 iron-sulfur cluster-binding protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein complement(621365..621865) Kosmotoga olearia TBF 19.5.1 7968766 YP_002940296.1 CDS Kole_0573 NC_012785.1 621862 622683 R PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: gur:Gura_3587 oxidoreductase FAD/NAD(P)-binding subunit; oxidoreductase FAD/NAD(P)-binding domain protein complement(621862..622683) Kosmotoga olearia TBF 19.5.1 7968767 YP_002940297.1 CDS Kole_0574 NC_012785.1 622680 623687 R PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: glo:Glov_0867 4Fe-4S ferredoxin iron-sulfur binding domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein complement(622680..623687) Kosmotoga olearia TBF 19.5.1 7968768 YP_002940298.1 CDS Kole_0575 NC_012785.1 623771 624178 R hypothetical protein complement(623771..624178) Kosmotoga olearia TBF 19.5.1 7968769 YP_002940299.1 CDS Kole_0576 NC_012785.1 624578 625231 R TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: hypothetical protein; HAD-superfamily hydrolase, subfamily IA, variant 3 complement(624578..625231) Kosmotoga olearia TBF 19.5.1 7968770 YP_002940300.1 CDS Kole_0577 NC_012785.1 625237 626292 R PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: baa:BA_3496 HTH_ARSR, helix_turn_helix, arsenical resistance operon repressor; ArsR family transcriptional regulator complement(625237..626292) Kosmotoga olearia TBF 19.5.1 7968771 YP_002940301.1 CDS Kole_0578 NC_012785.1 626292 627350 R PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: dal:Dalk_3679 ArsR family transcriptional regulator; ArsR family transcriptional regulator complement(626292..627350) Kosmotoga olearia TBF 19.5.1 7968772 YP_002940302.1 CDS Kole_0579 NC_012785.1 627582 627689 D hypothetical protein 627582..627689 Kosmotoga olearia TBF 19.5.1 7968773 YP_002940303.1 CDS Kole_0580 NC_012785.1 627862 628302 D hypothetical protein 627862..628302 Kosmotoga olearia TBF 19.5.1 7968774 YP_002940304.1 CDS Kole_0581 NC_012785.1 628321 629097 D PFAM: PfkB domain protein; KEGG: sei:SPC_3671 ribokinase; PfkB domain protein 628321..629097 Kosmotoga olearia TBF 19.5.1 7968775 YP_002940305.1 CDS Kole_0582 NC_012785.1 629606 630442 R hypothetical protein complement(629606..630442) Kosmotoga olearia TBF 19.5.1 7968776 YP_002940306.1 CDS Kole_0583 NC_012785.1 630426 630695 R PFAM: acylphosphatase; KEGG: nam:NAMH_0944 acylphosphatase; acylphosphatase complement(630426..630695) Kosmotoga olearia TBF 19.5.1 7968777 YP_002940307.1 CDS Kole_0584 NC_012785.1 630712 631353 R PFAM: protein of unknown function DUF1121; KEGG: wsu:WS1833 hypothetical protein; hypothetical protein complement(630712..631353) Kosmotoga olearia TBF 19.5.1 7968778 YP_002940308.1 CDS Kole_0585 NC_012785.1 631488 633758 D PFAM: glycoside hydrolase family 31; KEGG: scl:sce3449 Alpha-glucosidase family protein; Alpha-glucosidase 631488..633758 Kosmotoga olearia TBF 19.5.1 7968779 YP_002940309.1 CDS Kole_0586 NC_012785.1 633805 634545 D PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sat:SYN_03206 ABC transporter ATP-binding protein; ABC transporter 633805..634545 Kosmotoga olearia TBF 19.5.1 7968780 YP_002940310.1 CDS Kole_0587 NC_012785.1 634542 635498 D PFAM: SufBD protein; KEGG: dat:HRM2_00580 hypothetical protein; SufBD protein 634542..635498 Kosmotoga olearia TBF 19.5.1 7968781 YP_002940311.1 CDS Kole_0588 NC_012785.1 635516 636550 D PFAM: peptidase M42 family protein; peptidase M20; KEGG: baa:BA_1479 Peptidase_M20, peptidase family M20/M25/M40; peptidase M42 family protein 635516..636550 Kosmotoga olearia TBF 19.5.1 7968782 YP_002940312.1 CDS Kole_0589 NC_012785.1 636671 637975 D hypothetical protein 636671..637975 Kosmotoga olearia TBF 19.5.1 7968783 YP_002940313.1 CDS Kole_0590 NC_012785.1 638026 639678 R KEGG: spl:Spea_4083 metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; metal dependent phosphohydrolase complement(638026..639678) Kosmotoga olearia TBF 19.5.1 7968784 YP_002940314.1 CDS Kole_0591 NC_012785.1 639871 640437 D KEGG: GG21085 gene product from transcript GG21085-RA; hypothetical protein 639871..640437 Kosmotoga olearia TBF 19.5.1 7968785 YP_002940315.1 CDS Kole_0593 NC_012785.1 640686 642095 R KEGG: rty:RT0229 response regulator PleD; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; SMART: GGDEF domain containing protein; response regulator receiver; response regulator receiver modulated diguanylate cyclase complement(640686..642095) Kosmotoga olearia TBF 19.5.1 7968787 YP_002940316.1 CDS Kole_0594 NC_012785.1 642284 643126 R PFAM: protein of unknown function DUF114; KEGG: bbt:BBta_7800 hypothetical protein; hypothetical protein complement(642284..643126) Kosmotoga olearia TBF 19.5.1 7968788 YP_002940317.1 CDS Kole_0595 NC_012785.1 643145 644413 R PFAM: protein of unknown function DUF1063; KEGG: dal:Dalk_4447 protein of unknown function DUF1063; hypothetical protein complement(643145..644413) Kosmotoga olearia TBF 19.5.1 7968789 YP_002940318.1 CDS Kole_0596 NC_012785.1 644587 645246 R KEGG: rru:Rru_A1471 butyryl-CoA:acetate CoA transferase; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase; 3-oxoacid CoA-transferase, B subunit complement(644587..645246) Kosmotoga olearia TBF 19.5.1 7968790 YP_002940319.1 CDS Kole_0597 NC_012785.1 645243 645896 R KEGG: lch:Lcho_2490 3-oxoacid CoA-transferase, A subunit; TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase; 3-oxoacid CoA-transferase, A subunit complement(645243..645896) Kosmotoga olearia TBF 19.5.1 7968791 YP_002940320.1 CDS Kole_0598 NC_012785.1 645969 647174 R KEGG: shl:Shal_2748 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; acetyl-CoA acetyltransferase complement(645969..647174) Kosmotoga olearia TBF 19.5.1 7968792 YP_002940321.1 CDS Kole_0599 NC_012785.1 647376 647891 R TIGRFAM: cob(I)alamin adenosyltransferase; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; KEGG: dol:Dole_1228 cob(I)alamin adenosyltransferase; cob(I)alamin adenosyltransferase complement(647376..647891) Kosmotoga olearia TBF 19.5.1 7968793 YP_002940322.1 CDS Kole_0600 NC_012785.1 648054 648452 R PFAM: RbsD or FucU transport; KEGG: baa:BA_1254 simple sugar transport system permease protein; RbsD or FucU transport complement(648054..648452) Kosmotoga olearia TBF 19.5.1 7968794 YP_002940323.1 CDS Kole_0601 NC_012785.1 648449 649351 R TIGRFAM: ribokinase; PFAM: PfkB domain protein; KEGG: pmu:PM0152 ribokinase; ribokinase complement(648449..649351) Kosmotoga olearia TBF 19.5.1 7968795 YP_002940324.1 CDS Kole_0602 NC_012785.1 649402 650280 R PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: bha:BH3732 ribose ABC transporter (ribose-binding protein); periplasmic binding protein/LacI transcriptional regulator complement(649402..650280) Kosmotoga olearia TBF 19.5.1 7968796 YP_002940325.1 CDS Kole_0603 NC_012785.1 650322 651251 R PFAM: inner-membrane translocator; KEGG: mmw:Mmwyl1_1987 monosaccharide-transporting ATPase; inner-membrane translocator complement(650322..651251) Kosmotoga olearia TBF 19.5.1 7968797 YP_002940326.1 CDS Kole_0604 NC_012785.1 651257 652750 R PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: kpn:KPN_00510 ABC transporter; ABC transporter complement(651257..652750) Kosmotoga olearia TBF 19.5.1 7968798 YP_002940327.1 CDS Kole_0605 NC_012785.1 652737 653732 R PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: pat:Patl_0121 LacI family transcription regulator; LacI family transcriptional regulator complement(652737..653732) Kosmotoga olearia TBF 19.5.1 7968799 YP_002940328.1 CDS Kole_0606 NC_012785.1 654170 654772 D KEGG: nam:NAMH_0394 hypothetical protein; hypothetical protein 654170..654772 Kosmotoga olearia TBF 19.5.1 7968800 YP_002940329.1 CDS Kole_0607 NC_012785.1 654824 655459 R hypothetical protein complement(654824..655459) Kosmotoga olearia TBF 19.5.1 7968801 YP_002940330.1 CDS Kole_0608 NC_012785.1 655450 655659 R PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: pat:Patl_3871 XRE family transcriptional regulator; XRE family transcriptional regulator complement(655450..655659) Kosmotoga olearia TBF 19.5.1 7968802 YP_002940331.1 CDS Kole_0609 NC_012785.1 655858 656505 D PFAM: Transaldolase; KEGG: vpa:VPA1569 fructose-6-phosphate aldolase; Transaldolase 655858..656505 Kosmotoga olearia TBF 19.5.1 7968803 YP_002940332.1 CDS Kole_0610 NC_012785.1 656515 657486 D PFAM: PfkB domain protein; KEGG: bha:BH1857 fructokinase; PfkB domain protein 656515..657486 Kosmotoga olearia TBF 19.5.1 7968804 YP_002940333.1 CDS Kole_0611 NC_012785.1 657498 658199 R TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein; KEGG: dat:HRM2_17730 channel protein (hemolysin III family protein); channel protein, hemolysin III family complement(657498..658199) Kosmotoga olearia TBF 19.5.1 7968805 YP_002940334.1 CDS Kole_0612 NC_012785.1 658569 658874 D hypothetical protein 658569..658874 Kosmotoga olearia TBF 19.5.1 7968806 YP_002940335.1 CDS Kole_0613 NC_012785.1 658864 659460 D PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; metal dependent phosphohydrolase 658864..659460 Kosmotoga olearia TBF 19.5.1 7968807 YP_002940336.1 CDS Kole_0614 NC_012785.1 659604 661466 D PFAM: phospholipase/Carboxylesterase; KEGG: sus:Acid_1148 esterase; phospholipase/Carboxylesterase 659604..661466 Kosmotoga olearia TBF 19.5.1 7968808 YP_002940337.1 CDS Kole_0615 NC_012785.1 661742 662188 D PFAM: protein of unknown function UPF0157; KEGG: baa:BA_4064 hypothetical protein; hypothetical protein 661742..662188 Kosmotoga olearia TBF 19.5.1 7968809 YP_002940338.1 CDS Kole_0616 NC_012785.1 662199 662870 R PFAM: DNA alkylation repair enzyme; KEGG: swd:Swoo_2024 DNA alkylation repair enzyme; DNA alkylation repair enzyme complement(662199..662870) Kosmotoga olearia TBF 19.5.1 7968810 YP_002940339.1 CDS Kole_0617 NC_012785.1 662991 663623 R PFAM: Phosphoglycerate mutase; KEGG: baa:BA_2544 PGAM, phosphoglycerate mutase family; Phosphoglycerate mutase complement(662991..663623) Kosmotoga olearia TBF 19.5.1 7968811 YP_002940340.1 CDS Kole_0618 NC_012785.1 663851 664087 R hypothetical protein complement(663851..664087) Kosmotoga olearia TBF 19.5.1 7968812 YP_002940341.1 CDS Kole_0619 NC_012785.1 664382 665365 R KEGG: dal:Dalk_2332 nitroreductase; nitroreductase complement(664382..665365) Kosmotoga olearia TBF 19.5.1 7968813 YP_002940342.1 CDS Kole_0620 NC_012785.1 665527 666753 R PFAM: Choloylglycine hydrolase; peptidase C45 acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase; KEGG: lpc:LPC_2491 hypothetical protein; Choloylglycine hydrolase complement(665527..666753) Kosmotoga olearia TBF 19.5.1 7968814 YP_002940343.1 CDS Kole_0621 NC_012785.1 666753 666872 R hypothetical protein complement(666753..666872) Kosmotoga olearia TBF 19.5.1 7968815 YP_002940344.1 CDS Kole_0622 NC_012785.1 666862 667404 R PFAM: transcriptional regulator PadR family protein; KEGG: dat:HRM2_38900 transcriptional regulator (PadR family protein); PadR family transcriptional regulator complement(666862..667404) Kosmotoga olearia TBF 19.5.1 7968816 YP_002940345.1 CDS Kole_0623 NC_012785.1 667725 669008 D KEGG: dde:Dde_0972 phenylacetate-CoA ligase; Coenzyme F390 synthetase-like protein 667725..669008 Kosmotoga olearia TBF 19.5.1 7968817 YP_002940346.1 CDS Kole_0624 NC_012785.1 669560 670834 D PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: eba:ebA5789 (S)-1-phenylethanol dehydrogenase; short-chain dehydrogenase/reductase SDR 669560..670834 Kosmotoga olearia TBF 19.5.1 7968818 YP_002940347.1 CDS Kole_0626 NC_012785.1 671139 672926 D TIGRFAM: CoA-substrate-specific enzyme activase; PFAM: ATPase BadF/BadG/BcrA/BcrD type; KEGG: dal:Dalk_2669 CoA-substrate-specific enzyme activase; CoA-substrate-specific enzyme activase 671139..672926 Kosmotoga olearia TBF 19.5.1 7968820 YP_002940348.1 CDS Kole_0627 NC_012785.1 672959 673249 D PFAM: transposase IS3/IS911 family protein; KEGG: nha:Nham_4140 transposase IS3/IS911; transposase IS3/IS911 family protein 672959..673249 Kosmotoga olearia TBF 19.5.1 7968821 YP_002940349.1 CDS Kole_0628 NC_012785.1 673249 674079 D PFAM: Integrase catalytic region; KEGG: nis:NIS_0744 transposase; Integrase catalytic region 673249..674079 Kosmotoga olearia TBF 19.5.1 7968822 YP_002940350.1 CDS Kole_0629 NC_012785.1 674076 676532 D KEGG: dal:Dalk_2669 CoA-substrate-specific enzyme activase; CoA-substrate-specific enzyme activase 674076..676532 Kosmotoga olearia TBF 19.5.1 7968823 YP_002940351.1 CDS Kole_0630 NC_012785.1 676654 677286 R KEGG: gur:Gura_3461 hypothetical protein; hypothetical protein complement(676654..677286) Kosmotoga olearia TBF 19.5.1 7968824 YP_002940352.1 CDS Kole_0631 NC_012785.1 677496 677891 R PFAM: histidine triad (HIT) protein; KEGG: ppd:Ppro_1004 histidine triad (HIT) protein; histidine triad (HIT) protein complement(677496..677891) Kosmotoga olearia TBF 19.5.1 7968825 YP_002940353.1 CDS Kole_0632 NC_012785.1 677922 678245 R PFAM: Cupin 2 conserved barrel domain protein; KEGG: pca:Pcar_2869 hypothetical protein; Cupin 2 conserved barrel domain protein complement(677922..678245) Kosmotoga olearia TBF 19.5.1 7968826 YP_002940354.1 CDS Kole_0633 NC_012785.1 678353 679003 R PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: geo:Geob_2035 methyltransferase type 11; Methyltransferase type 11 complement(678353..679003) Kosmotoga olearia TBF 19.5.1 7969233 YP_002940355.1 CDS Kole_0634 NC_012785.1 679176 679757 D hypothetical protein 679176..679757 Kosmotoga olearia TBF 19.5.1 7969234 YP_002940356.1 CDS Kole_0635 NC_012785.1 679732 680592 D hypothetical protein 679732..680592 Kosmotoga olearia TBF 19.5.1 7969235 YP_002940357.1 CDS Kole_0636 NC_012785.1 680979 681749 D PFAM: purine or other phosphorylase family 1; KEGG: glo:Glov_2578 purine or other phosphorylase family 1; purine or other phosphorylase family 1 680979..681749 Kosmotoga olearia TBF 19.5.1 7969236 YP_002940358.1 CDS Kole_0637 NC_012785.1 682222 682683 R hypothetical protein complement(682222..682683) Kosmotoga olearia TBF 19.5.1 7969237 YP_002940359.1 CDS Kole_0638 NC_012785.1 682895 683797 R TIGRFAM: ribosome small subunit-dependent GTPase A; PFAM: GTPase EngC; KEGG: gme:Gmet_0794 GTPase EngC; ribosome small subunit-dependent GTPase A complement(682895..683797) Kosmotoga olearia TBF 19.5.1 7969238 YP_002940360.1 CDS Kole_0639 NC_012785.1 684088 684489 R PFAM: FMN-binding domain protein; KEGG: eca:ECA2794 hypothetical protein; FMN-binding domain protein complement(684088..684489) Kosmotoga olearia TBF 19.5.1 7969239 YP_002940361.1 CDS Kole_0640 NC_012785.1 684492 685088 R PFAM: regulatory protein TetR; KEGG: sbp:Sbal223_4083 TetR family transcriptional regulator; TetR family transcriptional regulator complement(684492..685088) Kosmotoga olearia TBF 19.5.1 7969240 YP_002940362.1 CDS Kole_0641 NC_012785.1 685093 685572 R KEGG: asu:Asuc_0513 protoporphyrinogen oxidase; Flavodoxin-like protein complement(685093..685572) Kosmotoga olearia TBF 19.5.1 7969241 YP_002940363.1 CDS Kole_0642 NC_012785.1 685732 685941 D hypothetical protein 685732..685941 Kosmotoga olearia TBF 19.5.1 7969242 YP_002940364.1 CDS Kole_0643 NC_012785.1 686054 687241 D PFAM: major facilitator superfamily MFS_1; KEGG: bpd:BURPS668_1999 major facilitator family transporter; major facilitator superfamily MFS_1 686054..687241 Kosmotoga olearia TBF 19.5.1 7969243 YP_002940365.1 CDS Kole_0644 NC_012785.1 687258 687578 D PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; KEGG: abb:ABBFA_000782 6-O-methylguanine DNA methyltransferase, DNA binding domain protein; Methylated-DNA-(protein)-cysteine S-methyltransferase DNA binding 687258..687578 Kosmotoga olearia TBF 19.5.1 7969244 YP_002940366.1 CDS Kole_0645 NC_012785.1 687670 688809 R TIGRFAM: isoaspartyl dipeptidase; PFAM: amidohydrolase; KEGG: mmw:Mmwyl1_4096 isoaspartyl dipeptidase; isoaspartyl dipeptidase complement(687670..688809) Kosmotoga olearia TBF 19.5.1 7969245 YP_002940367.1 CDS glpX NC_012785.1 689251 690258 D type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 689251..690258 Kosmotoga olearia TBF 19.5.1 7969246 YP_002940368.1 CDS Kole_0647 NC_012785.1 690393 691448 D PFAM: protein of unknown function DUF955; helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: vvy:VV0273 hypothetical protein; hypothetical protein 690393..691448 Kosmotoga olearia TBF 19.5.1 7969247 YP_002940369.1 CDS Kole_0648 NC_012785.1 691426 691938 D KEGG: gur:Gura_4038 hypothetical protein; hypothetical protein 691426..691938 Kosmotoga olearia TBF 19.5.1 7969248 YP_002940370.1 CDS Kole_0649 NC_012785.1 691960 692949 D PFAM: peptidase S15; KEGG: mxa:MXAN_6277 lipase; peptidase S15 691960..692949 Kosmotoga olearia TBF 19.5.1 7969249 YP_002940371.1 CDS Kole_0650 NC_012785.1 692973 693995 D hypothetical protein 692973..693995 Kosmotoga olearia TBF 19.5.1 7969250 YP_002940372.1 CDS Kole_0652 NC_012785.1 694378 695187 D hypothetical protein 694378..695187 Kosmotoga olearia TBF 19.5.1 7969252 YP_002940373.1 CDS Kole_0653 NC_012785.1 695307 695930 D hypothetical protein 695307..695930 Kosmotoga olearia TBF 19.5.1 7969253 YP_002940374.1 CDS Kole_0654 NC_012785.1 696096 696656 D hypothetical protein 696096..696656 Kosmotoga olearia TBF 19.5.1 7969254 YP_002940375.1 CDS Kole_0655 NC_012785.1 696788 697813 D hypothetical protein 696788..697813 Kosmotoga olearia TBF 19.5.1 7969255 YP_002940376.1 CDS Kole_0656 NC_012785.1 697829 698185 D PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: bar:GBAA1373 GntR family transcriptional regulator; GntR family transcriptional regulator 697829..698185 Kosmotoga olearia TBF 19.5.1 7969256 YP_002940377.1 CDS Kole_0657 NC_012785.1 698178 698744 D hypothetical protein 698178..698744 Kosmotoga olearia TBF 19.5.1 7969257 YP_002940378.1 CDS Kole_0658 NC_012785.1 698741 699601 D PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: baa:BA_2626 ABC transporter; ABC transporter 698741..699601 Kosmotoga olearia TBF 19.5.1 7969258 YP_002940379.1 CDS Kole_0659 NC_012785.1 699700 700374 R PFAM: Cupin 2 conserved barrel domain protein; Cupin 2 conserved barrel domain protein complement(699700..700374) Kosmotoga olearia TBF 19.5.1 7969259 YP_002940380.1 CDS Kole_0660 NC_012785.1 700698 702521 D KEGG: afr:AFE_1707 sensory box-containing diguanylate cyclase, TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold domain protein; PAS fold-4 domain protein; SMART: GGDEF domain containing protein; PAC repeat-containing protein; PAS domain containing protein; diguanylate cyclase with PAS/PAC sensor 700698..702521 Kosmotoga olearia TBF 19.5.1 7969260 YP_002940381.1 CDS Kole_0661 NC_012785.1 702543 702812 R TIGRFAM: CRISPR-associated protein Cas2; PFAM: protein of unknown function DUF196; KEGG: geo:Geob_3409 CRISPR-associated protein Cas2; CRISPR-associated protein Cas2 complement(702543..702812) Kosmotoga olearia TBF 19.5.1 7969261 YP_002940382.1 CDS Kole_0662 NC_012785.1 703621 704451 R PFAM: protein of unknown function DUF324; hypothetical protein complement(703621..704451) Kosmotoga olearia TBF 19.5.1 7969262 YP_002940383.1 CDS Kole_0663 NC_012785.1 704451 704849 R hypothetical protein complement(704451..704849) Kosmotoga olearia TBF 19.5.1 7969263 YP_002940384.1 CDS Kole_0664 NC_012785.1 704849 705793 R TIGRFAM: CRISPR-associated RAMP protein, Cmr4 family; PFAM: protein of unknown function DUF324; KEGG: mmw:Mmwyl1_2690 CRISPR-associated RAMP Cmr4 family protein family protein; CRISPR-associated RAMP protein, Cmr4 family complement(704849..705793) Kosmotoga olearia TBF 19.5.1 7969264 YP_002940385.1 CDS Kole_0665 NC_012785.1 705790 708771 R TIGRFAM: CRISPR-associated protein, Csx11 family; KEGG: hypothetical protein; CRISPR-associated protein, Csx11 family complement(705790..708771) Kosmotoga olearia TBF 19.5.1 7969265 YP_002940386.1 CDS Kole_0666 NC_012785.1 708805 710007 R PFAM: protein of unknown function DUF324; KEGG: msu:MS1649 hypothetical protein; hypothetical protein complement(708805..710007) Kosmotoga olearia TBF 19.5.1 7969266 YP_002940387.1 CDS Kole_0667 NC_012785.1 709997 711076 R TIGRFAM: CRISPR-associated RAMP protein, Cmr1 family; PFAM: protein of unknown function DUF324; KEGG: hypothetical protein; CRISPR-associated RAMP protein, Cmr1 family complement(709997..711076) Kosmotoga olearia TBF 19.5.1 7969267 YP_002940388.1 CDS Kole_0668 NC_012785.1 711097 711372 R TIGRFAM: CRISPR-associated protein Cas2; PFAM: protein of unknown function DUF196; KEGG: cha:CHAB381_0393 CRISPR-associated protein Cas2; CRISPR-associated protein Cas2 complement(711097..711372) Kosmotoga olearia TBF 19.5.1 7969268 YP_002940389.1 CDS Kole_0669 NC_012785.1 711369 712358 R TIGRFAM: CRISPR-associated protein Cas1; PFAM: protein of unknown function DUF48; KEGG: cff:CFF8240_0665 CRISPR-associated protein Cas1; CRISPR-associated protein Cas1 complement(711369..712358) Kosmotoga olearia TBF 19.5.1 7969269 YP_002940390.1 CDS Kole_0670 NC_012785.1 712366 712863 R TIGRFAM: CRISPR-associated protein Cas4; PFAM: protein of unknown function DUF83; KEGG: cff:CFF8240_0664 CRISPR-associated protein Cas4; CRISPR-associated protein Cas4 complement(712366..712863) Kosmotoga olearia TBF 19.5.1 7969270 YP_002940391.1 CDS Kole_0671 NC_012785.1 712860 715190 R KEGG: cco:CCC13826_1422 CRISPR-associated helicase Cas3 domain-containing protein; TIGRFAM: CRISPR-associated helicase Cas3; CRISPR-associated HD domain protein; PFAM: helicase domain protein; SMART: helicase domain protein; DEAD-like helicase; CRISPR-associated helicase Cas3 complement(712860..715190) Kosmotoga olearia TBF 19.5.1 7969271 YP_002940392.1 CDS Kole_0672 NC_012785.1 715183 715893 R TIGRFAM: CRISPR-associated protein Cas5, Hmari subtype; CRISPR-associated protein Cas5; PFAM: protein of unknown function DUF522; KEGG: cco:CCC13826_1421 CRISPR-associated protein Cas5; CRISPR-associated protein Cas5, Hmari subtype complement(715183..715893) Kosmotoga olearia TBF 19.5.1 7969272 YP_002940393.1 CDS Kole_0673 NC_012785.1 715905 716843 R TIGRFAM: CRISPR-associated protein, Csh2 family; CRISPR-associated protein, CT1132 family; PFAM: CRISPR-associated protein TM1801; KEGG: ccv:CCV52592_1292 CRISPR-associated protein, Csh2 family; CRISPR-associated protein, Csh2 family complement(715905..716843) Kosmotoga olearia TBF 19.5.1 7969273 YP_002940394.1 CDS Kole_0674 NC_012785.1 716846 718645 R hypothetical protein complement(716846..718645) Kosmotoga olearia TBF 19.5.1 7969274 YP_002940395.1 CDS Kole_0675 NC_012785.1 718652 719380 R TIGRFAM: CRISPR-associated protein Cas6; PFAM: protein of unknown function DUF57; CRISPR-associated protein Cas6 complement(718652..719380) Kosmotoga olearia TBF 19.5.1 7969275 YP_002940396.1 CDS Kole_0676 NC_012785.1 726162 727421 R PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: hypothetical LOC579607; oxidoreductase domain protein complement(726162..727421) Kosmotoga olearia TBF 19.5.1 7969276 YP_002940397.1 CDS Kole_0677 NC_012785.1 727418 728467 R PFAM: oxidoreductase domain protein; KEGG: baa:BA_4144 GFO_IDH_MocA, oxidoreductase family, NAD-binding Rossmann fold; oxidoreductase domain protein complement(727418..728467) Kosmotoga olearia TBF 19.5.1 7969277 YP_002940398.1 CDS Kole_0678 NC_012785.1 728585 730429 R hypothetical protein complement(728585..730429) Kosmotoga olearia TBF 19.5.1 7969278 YP_002940399.1 CDS Kole_0679 NC_012785.1 730539 731798 R PFAM: extracellular solute-binding protein family 1; KEGG: mes:Meso_4520 extracellular solute-binding protein, family 1; extracellular solute-binding protein family 1 complement(730539..731798) Kosmotoga olearia TBF 19.5.1 7969279 YP_002940400.1 CDS Kole_0680 NC_012785.1 731858 732676 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: oan:Oant_2483 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component complement(731858..732676) Kosmotoga olearia TBF 19.5.1 7969280 YP_002940401.1 CDS Kole_0681 NC_012785.1 732682 733548 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rlt:Rleg2_5336 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component complement(732682..733548) Kosmotoga olearia TBF 19.5.1 7969281 YP_002940402.1 CDS Kole_0682 NC_012785.1 733555 734730 R PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: bar:GBAA5107 N-acylamino acid racemase; Mandelate racemase/muconate lactonizing protein complement(733555..734730) Kosmotoga olearia TBF 19.5.1 7969282 YP_002940403.1 CDS Kole_0683 NC_012785.1 734720 735970 R hypothetical protein complement(734720..735970) Kosmotoga olearia TBF 19.5.1 7969283 YP_002940404.1 CDS Kole_0684 NC_012785.1 735972 736922 R PFAM: dihydrodipicolinate synthetase; KEGG: pol:Bpro_0687 dihydrodipicolinate synthetase; dihydrodipicolinate synthetase complement(735972..736922) Kosmotoga olearia TBF 19.5.1 7969284 YP_002940405.1 CDS Kole_0685 NC_012785.1 736915 738237 R KEGG: dde:Dde_3030 hypothetical protein; transcriptional regulator complement(736915..738237) Kosmotoga olearia TBF 19.5.1 7969285 YP_002940406.1 CDS Kole_0686 NC_012785.1 738417 739724 R PFAM: D-tagatose-bisphosphate aldolase class II accessory protein AgaZ; KEGG: sed:SeD_A3612 D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit; D-tagatose-bisphosphate aldolase class II accessory protein AgaZ complement(738417..739724) Kosmotoga olearia TBF 19.5.1 7969286 YP_002940407.1 CDS Kole_0687 NC_012785.1 739747 740712 R PFAM: ATPase BadF/BadG/BcrA/BcrD type; KEGG: bcj:BCAS0466 N-acetylglucosamine kinase; ATPase BadF/BadG/BcrA/BcrD type complement(739747..740712) Kosmotoga olearia TBF 19.5.1 7969287 YP_002940408.1 CDS Kole_0688 NC_012785.1 740712 741731 R PFAM: sugar isomerase (SIS); KEGG: rlt:Rleg2_4761 sugar isomerase (SIS); Glutamine--fructose-6-phosphate transaminase (isomerizing) complement(740712..741731) Kosmotoga olearia TBF 19.5.1 7969288 YP_002940409.1 CDS Kole_0689 NC_012785.1 741737 743008 R PFAM: oxidoreductase domain protein; KEGG: hypothetical LOC579607; oxidoreductase domain protein complement(741737..743008) Kosmotoga olearia TBF 19.5.1 7969289 YP_002940410.1 CDS Kole_0690 NC_012785.1 743041 745029 R PFAM: TM1410 hypothetical-related protein; Carbohydrate-binding family 9; KEGG: aav:Aave_1043 signal peptide protein; TM1410 hypothetical-related protein complement(743041..745029) Kosmotoga olearia TBF 19.5.1 7969290 YP_002940411.1 CDS Kole_0691 NC_012785.1 745034 745870 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bha:BH1866 sugar transport system (permease) (binding protein dependent transporter); binding-protein-dependent transport systems inner membrane component complement(745034..745870) Kosmotoga olearia TBF 19.5.1 7969291 YP_002940412.1 CDS Kole_0692 NC_012785.1 745867 746736 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bha:BH1865 sugar transport system (permease) (binding protein dependent transporter); binding-protein-dependent transport systems inner membrane component complement(745867..746736) Kosmotoga olearia TBF 19.5.1 7969292 YP_002940413.1 CDS Kole_0693 NC_012785.1 746818 748068 R PFAM: extracellular solute-binding protein family 1; KEGG: bha:BH1864 hypothetical protein; extracellular solute-binding protein family 1 complement(746818..748068) Kosmotoga olearia TBF 19.5.1 7969293 YP_002940414.1 CDS Kole_0694 NC_012785.1 748108 748866 R PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; SMART: regulatory protein DeoR; KEGG: csa:Csal_2105 DeoR family transcriptional regulator; DeoR family transcriptional regulator complement(748108..748866) Kosmotoga olearia TBF 19.5.1 7969294 YP_002940415.1 CDS Kole_0695 NC_012785.1 749857 751131 D catalyzes the formation of L-tryptophan from indole and L-serine; tryptophan synthase subunit beta 749857..751131 Kosmotoga olearia TBF 19.5.1 7969295 YP_002940416.1 CDS Kole_0696 NC_012785.1 751200 751754 R KEGG: bid:Bind_1584 general secretion pathway protein G; hypothetical protein complement(751200..751754) Kosmotoga olearia TBF 19.5.1 7969296 YP_002940417.1 CDS Kole_0697 NC_012785.1 752102 753289 D PFAM: major facilitator superfamily MFS_1; KEGG: bpd:BURPS668_1999 major facilitator family transporter; major facilitator superfamily MFS_1 752102..753289 Kosmotoga olearia TBF 19.5.1 7969297 YP_002940418.1 CDS Kole_0698 NC_012785.1 753569 754033 D PFAM: MOSC domain containing protein; KEGG: gbm:Gbem_2271 MOSC domain containing protein; MOSC domain containing protein 753569..754033 Kosmotoga olearia TBF 19.5.1 7969298 YP_002940419.1 CDS Kole_0699 NC_012785.1 754030 755262 D TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: MoeA domain protein domain I and II; MoeA domain protein domain IV; molybdopterin binding domain; KEGG: sat:SYN_00266 molybdopterin biosynthesis protein; molybdenum cofactor synthesis domain protein 754030..755262 Kosmotoga olearia TBF 19.5.1 7969299 YP_002940420.1 CDS Kole_0700 NC_012785.1 755270 756067 D TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; KEGG: gur:Gura_3323 molybdenum ABC transporter, periplasmic molybdate-binding protein; molybdenum ABC transporter, periplasmic molybdate-binding protein 755270..756067 Kosmotoga olearia TBF 19.5.1 7969300 YP_002940421.1 CDS Kole_0701 NC_012785.1 756090 756854 D TIGRFAM: molybdate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pca:Pcar_1736 NifC-like ABC-type porter; molybdate ABC transporter permease 756090..756854 Kosmotoga olearia TBF 19.5.1 7969301 YP_002940422.1 CDS Kole_0702 NC_012785.1 756866 757816 D KEGG: shm:Shewmr7_3972 molybdenum cofactor biosynthesis protein A; TIGRFAM: molybdenum cofactor biosynthesis protein A; PFAM: Radical SAM domain protein; molybdenum cofactor synthesis domain protein; SMART: Elongator protein 3/MiaB/NifB; molybdenum cofactor biosynthesis protein A 756866..757816 Kosmotoga olearia TBF 19.5.1 7969302 YP_002940423.1 CDS Kole_0703 NC_012785.1 757819 758304 D TIGRFAM: molybdenum cofactor biosynthesis protein C; PFAM: molybdopterin cofactor biosynthesis MoaC region; KEGG: sat:SYN_02926 molybdenum cofactor biosynthesis protein C; molybdenum cofactor biosynthesis protein C 757819..758304 Kosmotoga olearia TBF 19.5.1 7969303 YP_002940424.1 CDS Kole_0704 NC_012785.1 758301 758789 D TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: molybdopterin binding domain; KEGG: sat:SYN_02931 cytoplasmic protein; molybdenum cofactor synthesis domain protein 758301..758789 Kosmotoga olearia TBF 19.5.1 7969304 YP_002940425.1 CDS Kole_0705 NC_012785.1 758806 759798 R PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; KEGG: bsu:BSU29100 two-component sensor histidine kinase; PAS/PAC sensor signal transduction histidine kinase complement(758806..759798) Kosmotoga olearia TBF 19.5.1 7969305 YP_002940426.1 CDS Kole_0706 NC_012785.1 759795 760475 R PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: baa:BA_0573 REC, CheY-homologous receiver domain; two component transcriptional regulator, winged helix family complement(759795..760475) Kosmotoga olearia TBF 19.5.1 7969306 YP_002940427.1 CDS Kole_0707 NC_012785.1 760472 761143 R TIGRFAM: phosphate transport system regulatory protein PhoU; PFAM: PhoU family protein; KEGG: bar:GBAA4492 phosphate transporter PhoU; phosphate uptake regulator, PhoU complement(760472..761143) Kosmotoga olearia TBF 19.5.1 7969307 YP_002940428.1 CDS Kole_0708 NC_012785.1 761157 761912 R KEGG: tgr:Tgr7_2650 phosphate ABC transporter, ATP-binding protein; TIGRFAM: phosphate ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase; phosphate ABC transporter ATPase complement(761157..761912) Kosmotoga olearia TBF 19.5.1 7969308 YP_002940429.1 CDS Kole_0709 NC_012785.1 761909 762745 R TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: dol:Dole_1927 phosphate ABC transporter, inner membrane subunit PstA; phosphate ABC transporter permease complement(761909..762745) Kosmotoga olearia TBF 19.5.1 7969309 YP_002940430.1 CDS Kole_0710 NC_012785.1 762732 763610 R TIGRFAM: phosphate ABC transporter, inner membrane subunit PstC; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sfu:Sfum_2887 phosphate ABC transporter, inner membrane subunit PstC; phosphate ABC transporter permease complement(762732..763610) Kosmotoga olearia TBF 19.5.1 7969310 YP_002940431.1 CDS Kole_0711 NC_012785.1 763621 764445 R TIGRFAM: phosphate binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: dal:Dalk_1427 phosphate binding protein; phosphate binding protein complement(763621..764445) Kosmotoga olearia TBF 19.5.1 7969311 YP_002940432.1 CDS Kole_0712 NC_012785.1 764752 765636 D PFAM: glycosidase PH1107-related; KEGG: aba:Acid345_0916 glycosidase, PH1107-related; glycosidase PH1107-related 764752..765636 Kosmotoga olearia TBF 19.5.1 7969312 YP_002940433.1 CDS Kole_0713 NC_012785.1 765652 766599 D PFAM: glycosidase PH1107-related; Glycosyl hydrolase family 32 domain protein; KEGG: aba:Acid345_0916 glycosidase, PH1107-related; glycosidase PH1107-related 765652..766599 Kosmotoga olearia TBF 19.5.1 7969313 YP_002940434.1 CDS Kole_0715 NC_012785.1 767214 768593 D PFAM: major facilitator superfamily MFS_1; KEGG: pzu:PHZ_c2267 permease of the major facilitator superfamily; major facilitator superfamily MFS_1 767214..768593 Kosmotoga olearia TBF 19.5.1 7969315 YP_002940435.1 CDS Kole_0716 NC_012785.1 768714 769367 D PFAM: FeoA family protein; iron dependent repressor; SMART: iron dependent repressor; KEGG: dal:Dalk_2732 iron (metal) dependent repressor, DtxR family; iron (metal) dependent repressor, DtxR family 768714..769367 Kosmotoga olearia TBF 19.5.1 7969316 YP_002940436.1 CDS Kole_0717 NC_012785.1 769370 769591 D PFAM: FeoA family protein; KEGG: dat:HRM2_10920 Fur; FeoA family protein 769370..769591 Kosmotoga olearia TBF 19.5.1 7969317 YP_002940437.1 CDS Kole_0718 NC_012785.1 769593 771581 D TIGRFAM: ferrous iron transport protein B; small GTP-binding protein; PFAM: Ferrous iron transport protein B domain protein; GTP-binding protein HSR1-related; nucleoside recognition domain protein; Ferrous iron transport B domain protein; KEGG: dal:Dalk_1642 ferrous iron transport protein B; ferrous iron transport protein B 769593..771581 Kosmotoga olearia TBF 19.5.1 7969318 YP_002940438.1 CDS Kole_0719 NC_012785.1 771667 771897 R hypothetical protein complement(771667..771897) Kosmotoga olearia TBF 19.5.1 7969319 YP_002940439.1 CDS Kole_0720 NC_012785.1 771956 772738 R PFAM: GCN5-related N-acetyltransferase; KEGG: mes:Meso_0956 GCN5-related N-acetyltransferase; GCN5-related N-acetyltransferase complement(771956..772738) Kosmotoga olearia TBF 19.5.1 7969320 YP_002940440.1 CDS Kole_0721 NC_012785.1 772878 773597 R hypothetical protein complement(772878..773597) Kosmotoga olearia TBF 19.5.1 7969321 YP_002940441.1 CDS Kole_0722 NC_012785.1 773998 774435 D KEGG: neu:NE1602 general secretion pathway protein G; hypothetical protein 773998..774435 Kosmotoga olearia TBF 19.5.1 7969322 YP_002940442.1 CDS Kole_0723 NC_012785.1 774492 775022 R KEGG: saz:Sama_0331 hypothetical protein; hypothetical protein complement(774492..775022) Kosmotoga olearia TBF 19.5.1 7969323 YP_002940443.1 CDS Kole_0724 NC_012785.1 775381 775914 R PFAM: protein of unknown function DUF952; KEGG: rru:Rru_A0513 hypothetical protein; hypothetical protein complement(775381..775914) Kosmotoga olearia TBF 19.5.1 7969324 YP_002940444.1 CDS Kole_0725 NC_012785.1 776124 777344 D KEGG: sat:SYN_01802 coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; Coproporphyrinogen dehydrogenase 776124..777344 Kosmotoga olearia TBF 19.5.1 7969325 YP_002940445.1 CDS Kole_0726 NC_012785.1 777348 778973 R KEGG: sde:Sde_1294 polyhydroxyalkanoate synthesis repressor PhaR; hypothetical protein complement(777348..778973) Kosmotoga olearia TBF 19.5.1 7969326 YP_002940446.1 CDS Kole_0727 NC_012785.1 778945 779322 R KEGG: pub:SAR11_1219 fimbrial protein pilin; hypothetical protein complement(778945..779322) Kosmotoga olearia TBF 19.5.1 7969327 YP_002940447.1 CDS Kole_0728 NC_012785.1 779319 779828 R hypothetical protein complement(779319..779828) Kosmotoga olearia TBF 19.5.1 7969328 YP_002940448.1 CDS Kole_0730 NC_012785.1 781162 781515 D hypothetical protein 781162..781515 Kosmotoga olearia TBF 19.5.1 7969330 YP_002940449.1 CDS Kole_0731 NC_012785.1 781591 782676 D KEGG: bha:BH0421 N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; N-acetylglucosamine-6-phosphate deacetylase 781591..782676 Kosmotoga olearia TBF 19.5.1 7969331 YP_002940450.1 CDS Kole_0732 NC_012785.1 782691 783083 D hypothetical protein 782691..783083 Kosmotoga olearia TBF 19.5.1 7969332 YP_002940451.1 CDS Kole_0733 NC_012785.1 783080 783844 D PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; SMART: regulatory protein DeoR; KEGG: ses:SARI_04365 DNA-binding transcriptional regulator AgaR; DeoR family transcriptional regulator 783080..783844 Kosmotoga olearia TBF 19.5.1 7969333 YP_002940452.1 CDS Kole_0734 NC_012785.1 783889 784899 D PFAM: GCN5-related N-acetyltransferase; KEGG: bba:Bd0589 acetyltransferase; GCN5-related N-acetyltransferase 783889..784899 Kosmotoga olearia TBF 19.5.1 7969334 YP_002940453.1 CDS Kole_0735 NC_012785.1 784924 785937 D PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: dno:DNO_0697 M20 family peptidase; peptidase M20 784924..785937 Kosmotoga olearia TBF 19.5.1 7969335 YP_002940454.1 CDS Kole_0736 NC_012785.1 786073 787074 D PFAM: sugar isomerase (SIS); KEGG: rlt:Rleg2_4761 sugar isomerase (SIS); Glutamine--fructose-6-phosphate transaminase (isomerizing) 786073..787074 Kosmotoga olearia TBF 19.5.1 7969336 YP_002940455.1 CDS Kole_0737 NC_012785.1 787130 788062 D PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: vei:Veis_2597 tagatose-bisphosphate aldolase; Tagatose-bisphosphate aldolase 787130..788062 Kosmotoga olearia TBF 19.5.1 7969337 YP_002940456.1 CDS Kole_0738 NC_012785.1 788078 789688 R PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: sse:Ssed_3778 response regulator; metal dependent phosphohydrolase complement(788078..789688) Kosmotoga olearia TBF 19.5.1 7969338 YP_002940457.1 CDS Kole_0739 NC_012785.1 789775 790863 R KEGG: dal:Dalk_4194 transposase IS4 family protein; hypothetical protein complement(789775..790863) Kosmotoga olearia TBF 19.5.1 7969339 YP_002940458.1 CDS Kole_0740 NC_012785.1 791167 791856 D PFAM: nitroreductase; KEGG: gsu:GSU0819 hypothetical protein; nitroreductase 791167..791856 Kosmotoga olearia TBF 19.5.1 7969340 YP_002940459.1 CDS Kole_0741 NC_012785.1 792291 794060 D hypothetical protein 792291..794060 Kosmotoga olearia TBF 19.5.1 7969341 YP_002940460.1 CDS Kole_0742 NC_012785.1 794117 795325 R PFAM: iron-containing alcohol dehydrogenase; KEGG: dds:Ddes_2051 iron-containing alcohol dehydrogenase; iron-containing alcohol dehydrogenase complement(794117..795325) Kosmotoga olearia TBF 19.5.1 7969342 YP_002940461.1 CDS Kole_0743 NC_012785.1 795779 796447 R PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: hypothetical protein ; K06950; metal dependent phosphohydrolase complement(795779..796447) Kosmotoga olearia TBF 19.5.1 7969344 YP_002940462.1 CDS Kole_0744 NC_012785.1 796543 797304 D catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 796543..797304 Kosmotoga olearia TBF 19.5.1 7969345 YP_002940463.1 CDS Kole_0745 NC_012785.1 797305 797799 D cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 797305..797799 Kosmotoga olearia TBF 19.5.1 7969346 YP_002940464.1 CDS Kole_0746 NC_012785.1 797796 798731 D TIGRFAM: methionyl-tRNA formyltransferase; PFAM: formyl transferase domain protein; KEGG: gme:Gmet_3339 methionyl-tRNA formyltransferase; methionyl-tRNA formyltransferase 797796..798731 Kosmotoga olearia TBF 19.5.1 7969347 YP_002940465.1 CDS Kole_0747 NC_012785.1 798735 798950 D hypothetical protein 798735..798950 Kosmotoga olearia TBF 19.5.1 7969348 YP_002940466.1 CDS Kole_0748 NC_012785.1 799233 801740 D SMART: helicase c2; Helicase-like, DEXD box c2 type; DEAD-like helicase; KEGG: gur:Gura_4122 helicase C2; helicase c2 799233..801740 Kosmotoga olearia TBF 19.5.1 7969350 YP_002940467.1 CDS Kole_0749 NC_012785.1 801731 802360 D KEGG: mgm:Mmc1_1401 phosphoribosyltransferase; phosphoribosyltransferase 801731..802360 Kosmotoga olearia TBF 19.5.1 7969351 YP_002940468.1 CDS Kole_0750 NC_012785.1 802579 803586 D PFAM: glycosyl transferase group 1; KEGG: rpi:Rpic_3774 glycosyl transferase group 1; glycosyl transferase group 1 802579..803586 Kosmotoga olearia TBF 19.5.1 7969353 YP_002940469.1 CDS Kole_0751 NC_012785.1 803583 804584 D PFAM: conserved hypothetical protein; KEGG: ilo:IL0119 hypothetical protein; hypothetical protein 803583..804584 Kosmotoga olearia TBF 19.5.1 7969354 YP_002940470.1 CDS Kole_0752 NC_012785.1 804581 805738 R PFAM: glycosyl transferase group 1; KEGG: mfa:Mfla_0790 1,2-diacylglycerol 3-glucosyltransferase; glycosyl transferase group 1 complement(804581..805738) Kosmotoga olearia TBF 19.5.1 7969355 YP_002940471.1 CDS Kole_0754 NC_012785.1 806081 807484 R TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: glo:Glov_3565 MATE efflux family protein; MATE efflux family protein complement(806081..807484) Kosmotoga olearia TBF 19.5.1 7969357 YP_002940472.1 CDS Kole_0755 NC_012785.1 807681 808325 R KEGG: mca:MCA3077 ABC transporter, permease protein; hypothetical protein complement(807681..808325) Kosmotoga olearia TBF 19.5.1 7969358 YP_002940473.1 CDS Kole_0757 NC_012785.1 809353 810654 R PFAM: peptidase S41; KEGG: sus:Acid_0918 peptidase S41; peptidase S41 complement(809353..810654) Kosmotoga olearia TBF 19.5.1 7969360 YP_002940474.1 CDS Kole_0758 NC_012785.1 810789 812393 R PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; KEGG: rty:RT0691 lipid A export ATP-binding/permease protein MsbA; ABC transporter complement(810789..812393) Kosmotoga olearia TBF 19.5.1 7969361 YP_002940475.1 CDS Kole_0759 NC_012785.1 812439 813653 R PFAM: peptidase S41; KEGG: sus:Acid_0918 peptidase S41; peptidase S41 complement(812439..813653) Kosmotoga olearia TBF 19.5.1 7969362 YP_002940476.1 CDS Kole_0760 NC_012785.1 813792 815507 R PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; KEGG: dps:DP2634 ABC transporter ATP-binding protein; ABC transporter complement(813792..815507) Kosmotoga olearia TBF 19.5.1 7969363 YP_002940477.1 CDS Kole_0761 NC_012785.1 815504 816901 R PFAM: Radical SAM domain protein; KEGG: abu:Abu_0466 quinohemoprotein amine dehydrogenase, SAM-radical dependent activating subunit; Radical SAM domain protein complement(815504..816901) Kosmotoga olearia TBF 19.5.1 7969364 YP_002940478.1 CDS Kole_0762 NC_012785.1 817043 817147 R hypothetical protein complement(817043..817147) Kosmotoga olearia TBF 19.5.1 7969365 YP_002940479.1 CDS Kole_0763 NC_012785.1 817513 817650 R hypothetical protein complement(817513..817650) Kosmotoga olearia TBF 19.5.1 7969366 YP_002940480.1 CDS Kole_0764 NC_012785.1 817807 818304 D hypothetical protein 817807..818304 Kosmotoga olearia TBF 19.5.1 7969367 YP_002940481.1 CDS Kole_0765 NC_012785.1 818354 819568 D PFAM: transposase mutator type; KEGG: par:Psyc_0534 transposase mutator family protein; transposase mutator type 818354..819568 Kosmotoga olearia TBF 19.5.1 7969368 YP_002940482.1 CDS Kole_0766 NC_012785.1 819652 820482 R PFAM: Integrase catalytic region; KEGG: nis:NIS_0744 transposase; Integrase catalytic region complement(819652..820482) Kosmotoga olearia TBF 19.5.1 7969369 YP_002940483.1 CDS Kole_0767 NC_012785.1 820482 820772 R PFAM: transposase IS3/IS911 family protein; KEGG: nha:Nham_4140 transposase IS3/IS911; transposase IS3/IS911 family protein complement(820482..820772) Kosmotoga olearia TBF 19.5.1 7969370 YP_002940484.1 CDS Kole_0768 NC_012785.1 820856 821569 R PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bsu:BSU04490 hypothetical protein; ABC transporter complement(820856..821569) Kosmotoga olearia TBF 19.5.1 7969371 YP_002940485.1 CDS Kole_0769 NC_012785.1 822228 823562 R PFAM: Radical SAM domain protein; KEGG: afw:Anae109_2359 radical SAM domain-containing protein; Radical SAM domain protein complement(822228..823562) Kosmotoga olearia TBF 19.5.1 7969372 YP_002940486.1 CDS Kole_0770 NC_012785.1 823703 825001 R PFAM: Radical SAM domain protein; KEGG: abu:Abu_0466 quinohemoprotein amine dehydrogenase, SAM-radical dependent activating subunit; Radical SAM domain protein complement(823703..825001) Kosmotoga olearia TBF 19.5.1 7969373 YP_002940487.1 CDS Kole_0771 NC_012785.1 825025 826308 R PFAM: peptidase S41; KEGG: sus:Acid_0918 peptidase S41; peptidase S41 complement(825025..826308) Kosmotoga olearia TBF 19.5.1 7969374 YP_002940488.1 CDS Kole_0772 NC_012785.1 826434 826598 R hypothetical protein complement(826434..826598) Kosmotoga olearia TBF 19.5.1 7969375 YP_002940489.1 CDS Kole_0773 NC_012785.1 826733 828037 R PFAM: peptidase S41; KEGG: sus:Acid_0918 peptidase S41; peptidase S41 complement(826733..828037) Kosmotoga olearia TBF 19.5.1 7969376 YP_002940490.1 CDS Kole_0774 NC_012785.1 828165 828338 R hypothetical protein complement(828165..828338) Kosmotoga olearia TBF 19.5.1 7969377 YP_002940491.1 CDS Kole_0775 NC_012785.1 828706 829401 R PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bsu:BSU02750 Na+ ABC transporter ATP-binding protein; ABC transporter complement(828706..829401) Kosmotoga olearia TBF 19.5.1 7969378 YP_002940492.1 CDS Kole_0776 NC_012785.1 829414 830229 R PFAM: ABC-2 type transporter; KEGG: cff:CFF8240_0262 ABC-type multidrug transport system permease component; ABC transporter complement(829414..830229) Kosmotoga olearia TBF 19.5.1 7969379 YP_002940493.1 CDS Kole_0777 NC_012785.1 830236 830691 R hypothetical protein complement(830236..830691) Kosmotoga olearia TBF 19.5.1 7969380 YP_002940494.1 CDS Kole_0778 NC_012785.1 830685 830963 R hypothetical protein complement(830685..830963) Kosmotoga olearia TBF 19.5.1 7969381 YP_002940495.1 CDS Kole_0779 NC_012785.1 830960 831589 R PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: hpg:HPG27_778 osmoprotection protein; ABC transporter complement(830960..831589) Kosmotoga olearia TBF 19.5.1 7969382 YP_002940496.1 CDS Kole_0780 NC_012785.1 832022 832939 R KEGG: tdn:Suden_1026 periplasmic copper-binding; hypothetical protein complement(832022..832939) Kosmotoga olearia TBF 19.5.1 7969383 YP_002940497.1 CDS Kole_0781 NC_012785.1 832958 833389 R KEGG: hypothetical protein; hypothetical protein complement(832958..833389) Kosmotoga olearia TBF 19.5.1 7969384 YP_002940498.1 CDS Kole_0783 NC_012785.1 833903 834019 R hypothetical protein complement(833903..834019) Kosmotoga olearia TBF 19.5.1 7969386 YP_002940499.1 CDS Kole_0784 NC_012785.1 834309 835139 R PFAM: Integrase catalytic region; KEGG: nis:NIS_0744 transposase; Integrase catalytic region complement(834309..835139) Kosmotoga olearia TBF 19.5.1 7969387 YP_002940500.1 CDS Kole_0785 NC_012785.1 835139 835429 R PFAM: transposase IS3/IS911 family protein; KEGG: nha:Nham_4140 transposase IS3/IS911; transposase IS3/IS911 family protein complement(835139..835429) Kosmotoga olearia TBF 19.5.1 7969388 YP_002940501.1 CDS Kole_0786 NC_012785.1 835518 837044 D hypothetical protein 835518..837044 Kosmotoga olearia TBF 19.5.1 7969389 YP_002940502.1 CDS Kole_0787 NC_012785.1 837232 838518 R PFAM: major facilitator superfamily MFS_1; KEGG: bar:GBAA2664 permease; major facilitator superfamily MFS_1 complement(837232..838518) Kosmotoga olearia TBF 19.5.1 7969390 YP_002940503.1 CDS Kole_0788 NC_012785.1 838876 840411 D hypothetical protein 838876..840411 Kosmotoga olearia TBF 19.5.1 7969391 YP_002940504.1 CDS Kole_0789 NC_012785.1 840577 841833 R PFAM: major facilitator superfamily MFS_1; KEGG: bar:GBAA2577 permease; major facilitator superfamily MFS_1 complement(840577..841833) Kosmotoga olearia TBF 19.5.1 7969392 YP_002940505.1 CDS Kole_0790 NC_012785.1 841830 842081 R hypothetical protein complement(841830..842081) Kosmotoga olearia TBF 19.5.1 7969393 YP_002940506.1 CDS Kole_0791 NC_012785.1 842074 842187 R hypothetical protein complement(842074..842187) Kosmotoga olearia TBF 19.5.1 7969394 YP_002940507.1 CDS Kole_0792 NC_012785.1 842184 842819 R KEGG: mca:MCA3077 ABC transporter, permease protein; hypothetical protein complement(842184..842819) Kosmotoga olearia TBF 19.5.1 7968144 YP_002940508.1 CDS Kole_0793 NC_012785.1 842816 843736 R PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bha:BH3893 ABC transporter ATP-binding protein; ABC transporter complement(842816..843736) Kosmotoga olearia TBF 19.5.1 7968145 YP_002940509.1 CDS Kole_0794 NC_012785.1 843754 843945 R hypothetical protein complement(843754..843945) Kosmotoga olearia TBF 19.5.1 7968146 YP_002940510.1 CDS Kole_0795 NC_012785.1 844099 844554 R hypothetical protein complement(844099..844554) Kosmotoga olearia TBF 19.5.1 7968147 YP_002940511.1 CDS Kole_0796 NC_012785.1 844548 844826 R hypothetical protein complement(844548..844826) Kosmotoga olearia TBF 19.5.1 7968148 YP_002940512.1 CDS Kole_0797 NC_012785.1 844823 845452 R PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: hpg:HPG27_778 osmoprotection protein; ABC transporter complement(844823..845452) Kosmotoga olearia TBF 19.5.1 7968149 YP_002940513.1 CDS Kole_0798 NC_012785.1 845924 847585 R PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; KEGG: hpg:HPG27_348 multidrug resistance protein; ABC transporter complement(845924..847585) Kosmotoga olearia TBF 19.5.1 7968150 YP_002940514.1 CDS Kole_0799 NC_012785.1 848462 850114 D hypothetical protein 848462..850114 Kosmotoga olearia TBF 19.5.1 7968151 YP_002940515.1 CDS Kole_0800 NC_012785.1 850120 851406 R PFAM: major facilitator superfamily MFS_1; KEGG: bar:GBAA2664 permease; major facilitator superfamily MFS_1 complement(850120..851406) Kosmotoga olearia TBF 19.5.1 7968152 YP_002940516.1 CDS Kole_0801 NC_012785.1 851764 853314 D hypothetical protein 851764..853314 Kosmotoga olearia TBF 19.5.1 7968153 YP_002940517.1 CDS Kole_0802 NC_012785.1 853749 854411 R KEGG: pmy:Pmen_1784 glutamine amidotransferase, class-II; glutamine amidotransferase-like protein complement(853749..854411) Kosmotoga olearia TBF 19.5.1 7968154 YP_002940518.1 CDS Kole_0803 NC_012785.1 854898 855476 R PFAM: SNO glutamine amidotransferase; CobB/CobQ domain protein glutamine amidotransferase; KEGG: baa:BA_0606 SNO glutamine amidotransferase family; SNO glutamine amidotransferase complement(854898..855476) Kosmotoga olearia TBF 19.5.1 7968155 YP_002940519.1 CDS Kole_0804 NC_012785.1 855479 856357 R with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS complement(855479..856357) Kosmotoga olearia TBF 19.5.1 7968156 YP_002940520.1 CDS Kole_0805 NC_012785.1 856376 857677 R PFAM: Quinolinate phosphoribosyl transferase; KEGG: bar:GBAA4939 nicotinate phosphoribosyltransferase; Quinolinate phosphoribosyl transferase complement(856376..857677) Kosmotoga olearia TBF 19.5.1 7968157 YP_002940521.1 CDS Kole_0806 NC_012785.1 857674 858201 R PFAM: isochorismatase hydrolase; KEGG: sfu:Sfum_2603 isochorismatase hydrolase; isochorismatase hydrolase complement(857674..858201) Kosmotoga olearia TBF 19.5.1 7968158 YP_002940522.1 CDS Kole_0807 NC_012785.1 858298 859317 R hypothetical protein complement(858298..859317) Kosmotoga olearia TBF 19.5.1 7968159 YP_002940523.1 CDS Kole_0808 NC_012785.1 859314 860276 R KEGG: bha:BH1197 hypothetical protein; hypothetical protein complement(859314..860276) Kosmotoga olearia TBF 19.5.1 7968160 YP_002940524.1 CDS Kole_0809 NC_012785.1 860303 860674 R hypothetical protein complement(860303..860674) Kosmotoga olearia TBF 19.5.1 7968161 YP_002940525.1 CDS Kole_0810 NC_012785.1 860684 861061 R KEGG: scl:sce1452 hypothetical protein; hypothetical protein complement(860684..861061) Kosmotoga olearia TBF 19.5.1 7968162 YP_002940526.1 CDS Kole_0811 NC_012785.1 862120 863406 D PFAM: extracellular solute-binding protein family 1; KEGG: esa:ESA_01603 hypothetical protein; extracellular solute-binding protein family 1 862120..863406 Kosmotoga olearia TBF 19.5.1 7968163 YP_002940527.1 CDS Kole_0812 NC_012785.1 863475 864365 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: esa:ESA_01604 hypothetical protein; binding-protein-dependent transport systems inner membrane component 863475..864365 Kosmotoga olearia TBF 19.5.1 7968164 YP_002940528.1 CDS Kole_0813 NC_012785.1 864359 865330 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ect:ECIAI39_1664 sugar transporter subunit: permease component of ABC superfamily transporter; binding-protein-dependent transport systems inner membrane component 864359..865330 Kosmotoga olearia TBF 19.5.1 7968165 YP_002940529.1 CDS Kole_0814 NC_012785.1 865345 866550 D KEGG: dal:Dalk_2929 glycosyl transferase family 2; glycosyl transferase family 2 865345..866550 Kosmotoga olearia TBF 19.5.1 7968166 YP_002940530.1 CDS Kole_0815 NC_012785.1 866559 867386 D PFAM: sugar isomerase (SIS); helix-turn-helix protein RpiR; KEGG: bha:BH2675 RpiR transcriptional regulator; RpiR family transcriptional regulator 866559..867386 Kosmotoga olearia TBF 19.5.1 7968167 YP_002940531.1 CDS Kole_0816 NC_012785.1 867391 868047 R PFAM: alanine racemase domain protein; KEGG: sat:SYN_00571 alanine racemase domain-containing protein; alanine racemase domain protein complement(867391..868047) Kosmotoga olearia TBF 19.5.1 7968168 YP_002940532.1 CDS Kole_0817 NC_012785.1 868240 868779 D PFAM: GCN5-related N-acetyltransferase; KEGG: bha:BH2121 hypothetical protein; GCN5-related N-acetyltransferase 868240..868779 Kosmotoga olearia TBF 19.5.1 7968169 YP_002940533.1 CDS Kole_0818 NC_012785.1 868801 869466 D PFAM: glutamine amidotransferase class-I; KEGG: cff:CFF8240_0351 anthranilate synthase component II; glutamine amidotransferase class-I 868801..869466 Kosmotoga olearia TBF 19.5.1 7968170 YP_002940534.1 CDS Kole_0819 NC_012785.1 869493 870089 D KEGG: baa:BA_3595 peptidase_C15, pyroglutamyl peptidase; TIGRFAM: pyrrolidone-carboxylate peptidase; PFAM: peptidase C15 pyroglutamyl peptidase I; pyrrolidone-carboxylate peptidase 869493..870089 Kosmotoga olearia TBF 19.5.1 7968171 YP_002940535.1 CDS Kole_0820 NC_012785.1 870086 870820 D PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: tdn:Suden_0602 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase 870086..870820 Kosmotoga olearia TBF 19.5.1 7968172 YP_002940536.1 CDS Kole_0821 NC_012785.1 870939 872015 R PFAM: ABC-2 type transporter; KEGG: bba:Bd1879 ABC-type multidrug transporter permease protein; ABC transporter complement(870939..872015) Kosmotoga olearia TBF 19.5.1 7968173 YP_002940537.1 CDS Kole_0822 NC_012785.1 872012 873001 R KEGG: baa:BA_2299 ABC transporter; TIGRFAM: daunorubicin resistance ABC transporter ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase; daunorubicin resistance ABC transporter ATPase subunit complement(872012..873001) Kosmotoga olearia TBF 19.5.1 7968174 YP_002940538.1 CDS Kole_0823 NC_012785.1 872988 873500 R PFAM: transcriptional regulator PadR family protein; KEGG: gox:GOX0839 hypothetical protein; PadR family transcriptional regulator complement(872988..873500) Kosmotoga olearia TBF 19.5.1 7968175 YP_002940539.1 CDS Kole_0824 NC_012785.1 873627 873770 D hypothetical protein 873627..873770 Kosmotoga olearia TBF 19.5.1 7968176 YP_002940540.1 CDS Kole_0826 NC_012785.1 874105 874926 D TIGRFAM: degV family protein; PFAM: DegV family protein; KEGG: baa:BA_2750 DUF194, uncharacterized protein, DegV family COG1307; degV family protein 874105..874926 Kosmotoga olearia TBF 19.5.1 7968178 YP_002940541.1 CDS Kole_0827 NC_012785.1 875022 875249 R SMART: helix-turn-helix domain protein; KEGG: baa:BA_3511 HTH_XRE, helix-turn-helix XRE-family like proteins; XRE family transcriptional regulator complement(875022..875249) Kosmotoga olearia TBF 19.5.1 7968179 YP_002940542.1 CDS Kole_0828 NC_012785.1 875260 875820 R hypothetical protein complement(875260..875820) Kosmotoga olearia TBF 19.5.1 7968180 YP_002940543.1 CDS Kole_0829 NC_012785.1 876202 876822 D PFAM: ThiJ/PfpI domain protein; KEGG: sat:SYN_01335 isoprenoid biosynthesis protein; isoprenoid biosynthesis protein with amidotransferase-like domain 876202..876822 Kosmotoga olearia TBF 19.5.1 7968181 YP_002940544.1 CDS Kole_0830 NC_012785.1 877134 877478 R PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: bar:GBAA3800 hypothetical protein; MazG nucleotide pyrophosphohydrolase complement(877134..877478) Kosmotoga olearia TBF 19.5.1 7968182 YP_002940545.1 CDS Kole_0831 NC_012785.1 877531 878040 R PFAM: NUDIX hydrolase; KEGG: lpf:lpl1470 hypothetical protein; NUDIX hydrolase complement(877531..878040) Kosmotoga olearia TBF 19.5.1 7968183 YP_002940546.1 CDS Kole_0832 NC_012785.1 878132 878449 D PFAM: Thioredoxin domain; KEGG: baa:BA_0963 hypothetical protein; Thioredoxin domain protein 878132..878449 Kosmotoga olearia TBF 19.5.1 7968184 YP_002940547.1 CDS Kole_0833 NC_012785.1 878655 879008 D hypothetical protein 878655..879008 Kosmotoga olearia TBF 19.5.1 7968185 YP_002940548.1 CDS Kole_0834 NC_012785.1 879289 879945 D hypothetical protein 879289..879945 Kosmotoga olearia TBF 19.5.1 7968186 YP_002940549.1 CDS Kole_0835 NC_012785.1 880068 882560 R PFAM: protein of unknown function DUF214; KEGG: geo:Geob_2022 protein of unknown function DUF214; hypothetical protein complement(880068..882560) Kosmotoga olearia TBF 19.5.1 7968187 YP_002940550.1 CDS Kole_0836 NC_012785.1 882570 883265 R PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: noc:Noc_2214 ABC transporter, ATPase subunit; ABC transporter complement(882570..883265) Kosmotoga olearia TBF 19.5.1 7968188 YP_002940551.1 CDS Kole_0837 NC_012785.1 883338 884594 R PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: gsu:GSU0452 sensor histidine kinase; histidine kinase complement(883338..884594) Kosmotoga olearia TBF 19.5.1 7968189 YP_002940552.1 CDS Kole_0838 NC_012785.1 884594 885274 R PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: baa:BA_0573 REC, CheY-homologous receiver domain; two component transcriptional regulator, winged helix family complement(884594..885274) Kosmotoga olearia TBF 19.5.1 7968190 YP_002940553.1 CDS Kole_0839 NC_012785.1 885357 886376 R KEGG: afw:Anae109_2420 hypothetical protein; hypothetical protein complement(885357..886376) Kosmotoga olearia TBF 19.5.1 7968191 YP_002940554.1 CDS Kole_0840 NC_012785.1 886473 887330 R KEGG: afw:Anae109_4243 hypothetical protein; hypothetical protein complement(886473..887330) Kosmotoga olearia TBF 19.5.1 7968192 YP_002940555.1 CDS Kole_0841 NC_012785.1 887693 888778 R TIGRFAM: peptide chain release factor 1; PFAM: Class I peptide chain release factor; PCRF domain protein; KEGG: sfu:Sfum_1713 peptide chain release factor 1; peptide chain release factor 1 complement(887693..888778) Kosmotoga olearia TBF 19.5.1 7968193 YP_002940556.1 CDS Kole_0842 NC_012785.1 888775 889830 R TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; KEGG: bbr:BB0791 twitching mobility protein; twitching motility protein complement(888775..889830) Kosmotoga olearia TBF 19.5.1 7968194 YP_002940557.1 CDS Kole_0843 NC_012785.1 889943 891376 D PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: ank:AnaeK_4258 alpha amylase catalytic region; alpha amylase catalytic region 889943..891376 Kosmotoga olearia TBF 19.5.1 7968195 YP_002940558.1 CDS Kole_0844 NC_012785.1 891493 892440 D TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: bar:GBAA4640 cation efflux family protein; cation diffusion facilitator family transporter 891493..892440 Kosmotoga olearia TBF 19.5.1 7968196 YP_002940559.1 CDS Kole_0845 NC_012785.1 892466 893953 D KEGG: glo:Glov_2722 response regulator receiver modulated metal dependent phosphohydrolase; TIGRFAM: PAS sensor protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: PAS domain containing protein; PAS/PAC sensor protein 892466..893953 Kosmotoga olearia TBF 19.5.1 7968197 YP_002940560.1 CDS Kole_0846 NC_012785.1 893990 894580 D PFAM: Rubrerythrin; KEGG: sat:SYN_02523 rubrerythrin; Rubrerythrin 893990..894580 Kosmotoga olearia TBF 19.5.1 7968198 YP_002940561.1 CDS Kole_0847 NC_012785.1 894628 896283 R KEGG: PCK1; phosphoenolpyruvate carboxykinase; hypothetical protein complement(894628..896283) Kosmotoga olearia TBF 19.5.1 7968199 YP_002940562.1 CDS Kole_0848 NC_012785.1 896526 897845 D PFAM: protein of unknown function DUF195; KEGG: dol:Dole_3209 hypothetical protein; hypothetical protein 896526..897845 Kosmotoga olearia TBF 19.5.1 7968200 YP_002940563.1 CDS Kole_0849 NC_012785.1 898291 899145 D PFAM: protein of unknown function DUF89; KEGG: dal:Dalk_1756 protein of unknown function DUF89; hypothetical protein 898291..899145 Kosmotoga olearia TBF 19.5.1 7968201 YP_002940564.1 CDS Kole_0850 NC_012785.1 899145 899627 D PFAM: GCN5-related N-acetyltransferase; KEGG: ypg:YpAngola_A3118 spermidine acetyltransferase; GCN5-related N-acetyltransferase 899145..899627 Kosmotoga olearia TBF 19.5.1 7968202 YP_002940565.1 CDS Kole_0851 NC_012785.1 900199 901125 R TIGRFAM: 1-phosphofructokinase; PFAM: PfkB domain protein; KEGG: gbm:Gbem_3234 1-phosphofructokinase; 1-phosphofructokinase complement(900199..901125) Kosmotoga olearia TBF 19.5.1 7968203 YP_002940566.1 CDS Kole_0852 NC_012785.1 901130 901489 R hypothetical protein complement(901130..901489) Kosmotoga olearia TBF 19.5.1 7968204 YP_002940567.1 CDS Kole_0853 NC_012785.1 901510 902205 R PFAM: protein of unknown function DUF558; KEGG: sat:SYN_02278 cytoplasmic protein; hypothetical protein complement(901510..902205) Kosmotoga olearia TBF 19.5.1 7968205 YP_002940568.1 CDS Kole_0854 NC_012785.1 902206 903480 R catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase complement(902206..903480) Kosmotoga olearia TBF 19.5.1 7968206 YP_002940569.1 CDS Kole_0855 NC_012785.1 903477 904145 R PFAM: OstA family protein; KEGG: hypothetical protein; OstA family protein complement(903477..904145) Kosmotoga olearia TBF 19.5.1 7968207 YP_002940570.1 CDS Kole_0856 NC_012785.1 904142 904603 R PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: bha:BH3072 transcriptional regulator; MarR family transcriptional regulator complement(904142..904603) Kosmotoga olearia TBF 19.5.1 7968208 YP_002940571.1 CDS rnhB NC_012785.1 904935 905618 D RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 904935..905618 Kosmotoga olearia TBF 19.5.1 7968209 YP_002940572.1 CDS Kole_0858 NC_012785.1 905634 906404 D TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: gur:Gura_3259 nucleoside triphosphate pyrophosphohydrolase; MazG family protein 905634..906404 Kosmotoga olearia TBF 19.5.1 7968210 YP_002940573.1 CDS Kole_0859 NC_012785.1 906401 907372 D KEGG: ftn:FTN_0559 peptidyl-prolyl cis-trans isomerase (PPIase); hypothetical protein 906401..907372 Kosmotoga olearia TBF 19.5.1 7968211 YP_002940574.1 CDS Kole_0860 NC_012785.1 907376 907681 D PFAM: protein of unknown function DUF59; KEGG: nis:NIS_1811 hypothetical protein; hypothetical protein 907376..907681 Kosmotoga olearia TBF 19.5.1 7968212 YP_002940575.1 CDS Kole_0861 NC_012785.1 907684 908532 D TIGRFAM: modification methylase, HemK family; PFAM: methyltransferase small; ribosomal L11 methyltransferase; KEGG: sat:SYN_01794 peptide release factor-glutamine N5-methyltransferase; modification methylase, HemK family 907684..908532 Kosmotoga olearia TBF 19.5.1 7968213 YP_002940576.1 CDS Kole_0862 NC_012785.1 908507 909256 R Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase complement(908507..909256) Kosmotoga olearia TBF 19.5.1 7968214 YP_002940577.1 CDS Kole_0863 NC_012785.1 909269 909859 R hypothetical protein complement(909269..909859) Kosmotoga olearia TBF 19.5.1 7968215 YP_002940578.1 CDS Kole_0864 NC_012785.1 910015 910998 D catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 910015..910998 Kosmotoga olearia TBF 19.5.1 7968216 YP_002940579.1 CDS Kole_0865 NC_012785.1 911001 911693 D PFAM: chromosome segregation and condensation protein ScpA; KEGG: dal:Dalk_5224 chromosome segregation and condensation protein ScpA; chromosome segregation and condensation protein ScpA 911001..911693 Kosmotoga olearia TBF 19.5.1 7968217 YP_002940580.1 CDS Kole_0866 NC_012785.1 911690 912307 D TIGRFAM: segregation and condensation protein B; PFAM: chromosome segregation and condensation protein ScpB; KEGG: baa:BA_4737 segregation and condensation protein B; chromosome segregation and condensation protein, ScpB 911690..912307 Kosmotoga olearia TBF 19.5.1 7968218 YP_002940581.1 CDS Kole_0867 NC_012785.1 912330 912947 D PFAM: pseudouridine synthase; KEGG: gur:Gura_2505 pseudouridine synthase; pseudouridine synthase 912330..912947 Kosmotoga olearia TBF 19.5.1 7968219 YP_002940582.1 CDS Kole_0868 NC_012785.1 913125 914729 D PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ABC transporter family protein; ABC transporter 913125..914729 Kosmotoga olearia TBF 19.5.1 7968220 YP_002940583.1 CDS Kole_0869 NC_012785.1 914941 915876 R PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: cju:C8J_0699 ABC transport system ATP-binding protein; ABC transporter complement(914941..915876) Kosmotoga olearia TBF 19.5.1 7968221 YP_002940584.1 CDS Kole_0871 NC_012785.1 916338 917525 D TIGRFAM: diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: cha:CHAB381_1301 diaminopimelate decarboxylase; diaminopimelate decarboxylase 916338..917525 Kosmotoga olearia TBF 19.5.1 7968223 YP_002940585.1 CDS Kole_0872 NC_012785.1 917832 918974 R TIGRFAM: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; PFAM: peptidase S13 D-Ala-D-Ala carboxypeptidase C; KEGG: slo:Shew_1962 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase complement(917832..918974) Kosmotoga olearia TBF 19.5.1 7968224 YP_002940586.1 CDS Kole_0873 NC_012785.1 918971 919810 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: oan:Oant_2483 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component complement(918971..919810) Kosmotoga olearia TBF 19.5.1 7967414 YP_002940587.1 CDS Kole_0874 NC_012785.1 919818 920705 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: avi:Avi_7347 ABC transporter membrane spanning protein (sugar); binding-protein-dependent transport systems inner membrane component complement(919818..920705) Kosmotoga olearia TBF 19.5.1 7967415 YP_002940588.1 CDS Kole_0875 NC_012785.1 920776 921996 R PFAM: extracellular solute-binding protein family 1; KEGG: mes:Meso_4520 extracellular solute-binding protein, family 1; extracellular solute-binding protein family 1 complement(920776..921996) Kosmotoga olearia TBF 19.5.1 7967416 YP_002940589.1 CDS Kole_0876 NC_012785.1 921999 923585 R PFAM: glycoside hydrolase family 3 domain protein; KEGG: beta-N-acetylglucosaminidase, ; K01207 beta-N-acetylhexosaminidase; glycoside hydrolase family 3 domain protein complement(921999..923585) Kosmotoga olearia TBF 19.5.1 7967417 YP_002940590.1 CDS Kole_0877 NC_012785.1 923591 924334 R PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: bha:BH0419 GntR family transcriptional regulator; GntR family transcriptional regulator complement(923591..924334) Kosmotoga olearia TBF 19.5.1 7967418 YP_002940591.1 CDS murQ NC_012785.1 924417 925328 R catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid-6-phosphate etherase complement(924417..925328) Kosmotoga olearia TBF 19.5.1 7967419 YP_002940592.1 CDS Kole_0879 NC_012785.1 925415 926407 D PFAM: beta-lactamase; KEGG: afr:AFE_2172 beta-lactamase; beta-lactamase 925415..926407 Kosmotoga olearia TBF 19.5.1 7967420 YP_002940593.1 CDS anmK NC_012785.1 926409 927512 D catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 926409..927512 Kosmotoga olearia TBF 19.5.1 7967421 YP_002940594.1 CDS Kole_0881 NC_012785.1 927516 928319 R KEGG: hypothetical protein; hypothetical protein complement(927516..928319) Kosmotoga olearia TBF 19.5.1 7967422 YP_002940595.1 CDS Kole_0882 NC_012785.1 928346 929299 R PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: sfu:Sfum_3914 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding complement(928346..929299) Kosmotoga olearia TBF 19.5.1 7967423 YP_002940596.1 CDS Kole_0883 NC_012785.1 929664 930944 R PFAM: Citrate transporter; Arsenical pump membrane protein; KEGG: baa:BA_0017 arsenical pump membrane protein; Citrate transporter complement(929664..930944) Kosmotoga olearia TBF 19.5.1 7967424 YP_002940597.1 CDS Kole_0884 NC_012785.1 931045 933429 R PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Torsin; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: AAA ATPase; KEGG: baa:BA_0670 Clp_N, Clp amino terminal domain; ATPase AAA-2 domain protein complement(931045..933429) Kosmotoga olearia TBF 19.5.1 7967425 YP_002940598.1 CDS Kole_0885 NC_012785.1 933490 933942 R PFAM: heat shock protein Hsp20; CS; KEGG: bbt:BBta_3527 HspC2 heat shock protein; heat shock protein Hsp20 complement(933490..933942) Kosmotoga olearia TBF 19.5.1 7967426 YP_002940599.1 CDS dnaK NC_012785.1 933981 935813 R heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK complement(933981..935813) Kosmotoga olearia TBF 19.5.1 7967427 YP_002940600.1 CDS Kole_0887 NC_012785.1 936079 936762 D PFAM: protein of unknown function DUF47; KEGG: swp:swp_0813 hypothetical protein; hypothetical protein 936079..936762 Kosmotoga olearia TBF 19.5.1 7967428 YP_002940601.1 CDS Kole_0888 NC_012785.1 936797 938011 D PFAM: phosphate transporter; KEGG: dal:Dalk_4122 phosphate transporter; phosphate transporter 936797..938011 Kosmotoga olearia TBF 19.5.1 7967429 YP_002940602.1 CDS Kole_0889 NC_012785.1 938001 939053 R hypothetical protein complement(938001..939053) Kosmotoga olearia TBF 19.5.1 7967430 YP_002940603.1 CDS Kole_0890 NC_012785.1 939065 943357 R KEGG: bsu:BSU16580 DNA polymerase III PolC; TIGRFAM: DNA polymerase III, alpha subunit; DNA polymerase III, epsilon subunit; PFAM: DNA polymerase III alpha subunit; Exonuclease RNase T and DNA polymerase III; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; SMART: Exonuclease; phosphoesterase PHP domain protein; DNA polymerase III, alpha subunit complement(939065..943357) Kosmotoga olearia TBF 19.5.1 7967431 YP_002940604.1 CDS ruvC NC_012785.1 943354 943860 R endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase complement(943354..943860) Kosmotoga olearia TBF 19.5.1 7967432 YP_002940605.1 CDS Kole_0892 NC_012785.1 944049 944798 R KEGG: dol:Dole_1502 ribonuclease III; TIGRFAM: ribonuclease III; PFAM: ribonuclease III; double-stranded RNA binding domain protein; SMART: ribonuclease III; double-stranded RNA binding domain protein; ribonuclease III complement(944049..944798) Kosmotoga olearia TBF 19.5.1 7967433 YP_002940606.1 CDS Kole_0893 NC_012785.1 944795 946699 R catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase complement(944795..946699) Kosmotoga olearia TBF 19.5.1 7967434 YP_002940607.1 CDS Kole_0894 NC_012785.1 946721 947614 R PFAM: PSP1 domain protein; KEGG: bha:BH0045 signal peptidase-like protein; PSP1 domain protein complement(946721..947614) Kosmotoga olearia TBF 19.5.1 7967435 YP_002940608.1 CDS Kole_0895 NC_012785.1 947630 948661 R KEGG: gme:Gmet_2319 DNA polymerase III, delta prime subunit; DNA polymerase III gamma/tau subunits-like protein complement(947630..948661) Kosmotoga olearia TBF 19.5.1 7967436 YP_002940609.1 CDS Kole_0896 NC_012785.1 948729 949172 D KEGG: bsu:BSU22730 nucleoside diphosphate kinase; PFAM: nucleoside diphosphate kinase; SMART: nucleoside diphosphate kinase; Nucleoside-diphosphate kinase 948729..949172 Kosmotoga olearia TBF 19.5.1 7967437 YP_002940610.1 CDS Kole_0897 NC_012785.1 949172 950353 D PFAM: methyltransferase small; protein of unknown function Met10; RNA methylase; SMART: PUA domain containing protein; KEGG: mca:MCA1049 hypothetical protein; methyltransferase small 949172..950353 Kosmotoga olearia TBF 19.5.1 7967438 YP_002940611.1 CDS Kole_0898 NC_012785.1 950359 951168 D hypothetical protein 950359..951168 Kosmotoga olearia TBF 19.5.1 7967439 YP_002940612.1 CDS Kole_0899 NC_012785.1 951179 952303 D KEGG: bha:BH1086 required for glycogen biosynthesis; TIGRFAM: glucose-1-phosphate adenylyltransferase, GlgD subunit; PFAM: Nucleotidyl transferase; glucose-1-phosphate adenylyltransferase, GlgD subunit 951179..952303 Kosmotoga olearia TBF 19.5.1 7967440 YP_002940613.1 CDS glgC NC_012785.1 952314 953585 D catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 952314..953585 Kosmotoga olearia TBF 19.5.1 7967441 YP_002940614.1 CDS Kole_0901 NC_012785.1 953602 953934 D hypothetical protein 953602..953934 Kosmotoga olearia TBF 19.5.1 7967442 YP_002940615.1 CDS ushA NC_012785.1 953940 955421 D catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor 953940..955421 Kosmotoga olearia TBF 19.5.1 7967443 YP_002940616.1 CDS Kole_0903 NC_012785.1 955584 956906 D TIGRFAM: electron transport complex, RnfABCDGE type, C subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; KEGG: psa:PST_1210 electron transport complex protein RnfC; electron transport complex, RnfABCDGE type, C subunit 955584..956906 Kosmotoga olearia TBF 19.5.1 7967444 YP_002940617.1 CDS Kole_0904 NC_012785.1 956903 957844 D TIGRFAM: electron transport complex, RnfABCDGE type, D subunit; PFAM: NQR2 and RnfD family protein; KEGG: pca:Pcar_0262 NADH:ubiquinone oxidoreductase, RnfD subunit-like; electron transport complex, RnfABCDGE type, D subunit 956903..957844 Kosmotoga olearia TBF 19.5.1 7967445 YP_002940618.1 CDS Kole_0905 NC_012785.1 957837 958565 D TIGRFAM: electron transport complex, RnfABCDGE type, G subunit; KEGG: tcx:Tcr_1032 electron transport complex, RnfABCDGE type, G subunit; electron transport complex, RnfABCDGE type, G subunit 957837..958565 Kosmotoga olearia TBF 19.5.1 7967446 YP_002940619.1 CDS Kole_0906 NC_012785.1 958565 959188 D in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex RsxE subunit 958565..959188 Kosmotoga olearia TBF 19.5.1 7967447 YP_002940620.1 CDS Kole_0907 NC_012785.1 959201 959794 D TIGRFAM: electron transport complex, RnfABCDGE type, A subunit; PFAM: RnfA-Nqr electron transport subunit; KEGG: pca:Pcar_0265 NADH:ubiquinone oxidoreductase, RnfA subunit-like; electron transport complex, RnfABCDGE type, A subunit 959201..959794 Kosmotoga olearia TBF 19.5.1 7967448 YP_002940621.1 CDS Kole_0908 NC_012785.1 959808 960500 D PFAM: Fe-S cluster domain protein; KEGG: rsq:Rsph17025_3193 respiratory-chain NADH dehydrogenase domain-containing protein; Fe-S cluster domain protein 959808..960500 Kosmotoga olearia TBF 19.5.1 7967449 YP_002940622.1 CDS Kole_0909 NC_012785.1 960504 961637 D catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 960504..961637 Kosmotoga olearia TBF 19.5.1 7967450 YP_002940623.1 CDS Kole_0910 NC_012785.1 961625 963139 D PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; KEGG: sde:Sde_2590 peptidase RseP; peptidase M50 961625..963139 Kosmotoga olearia TBF 19.5.1 7967451 YP_002940624.1 CDS ispG NC_012785.1 963136 964179 D catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 963136..964179 Kosmotoga olearia TBF 19.5.1 7967452 YP_002940625.1 CDS Kole_0912 NC_012785.1 964176 965147 D TIGRFAM: L-lactate dehydrogenase; PFAM: Lactate/malate dehydrogenase; KEGG: bar:GBAA5125 L-lactate dehydrogenase; L-lactate dehydrogenase 964176..965147 Kosmotoga olearia TBF 19.5.1 7967453 YP_002940626.1 CDS Kole_0913 NC_012785.1 965504 966580 D PFAM: PEGA domain protein; KEGG: ret:RHE_PE00129 hypothetical protein; PEGA domain protein 965504..966580 Kosmotoga olearia TBF 19.5.1 7967454 YP_002940627.1 CDS Kole_0914 NC_012785.1 966715 967608 D PFAM: protein of unknown function DUF6 transmembrane; KEGG: gsu:GSU3407 hypothetical protein; hypothetical protein 966715..967608 Kosmotoga olearia TBF 19.5.1 7967455 YP_002940628.1 CDS Kole_0915 NC_012785.1 967610 968275 D PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: bha:BH0372 two-component response regulator; two component transcriptional regulator, winged helix family 967610..968275 Kosmotoga olearia TBF 19.5.1 7967456 YP_002940629.1 CDS Kole_0916 NC_012785.1 968262 969572 D PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: bsu:BSU13260 hypothetical protein; histidine kinase 968262..969572 Kosmotoga olearia TBF 19.5.1 7967457 YP_002940630.1 CDS Kole_0917 NC_012785.1 969584 971731 R PFAM: RNA binding S1 domain protein; SMART: Resolvase RNase H domain protein fold; RNA binding S1 domain protein; KEGG: baa:BA_0825 ribosomal protein S1-like RNA-binding domain; RNA binding S1 domain protein complement(969584..971731) Kosmotoga olearia TBF 19.5.1 7967458 YP_002940631.1 CDS Kole_0918 NC_012785.1 971724 972680 R PFAM: Pyruvate kinase barrel; KEGG: hypothetical protein ; K00873 pyruvate kinase; Pyruvate kinase complement(971724..972680) Kosmotoga olearia TBF 19.5.1 7967459 YP_002940632.1 CDS Kole_0919 NC_012785.1 972789 973760 D PFAM: protein of unknown function DUF129; KEGG: rpb:RPB_4408 hypothetical protein; hypothetical protein 972789..973760 Kosmotoga olearia TBF 19.5.1 7967460 YP_002940633.1 CDS Kole_0920 NC_012785.1 973787 974002 R PFAM: Heavy metal transport/detoxification protein; Heavy metal transport/detoxification protein complement(973787..974002) Kosmotoga olearia TBF 19.5.1 7967461 YP_002940634.1 CDS Kole_0921 NC_012785.1 974291 974737 R KEGG: neu:NE1602 general secretion pathway protein G; hypothetical protein complement(974291..974737) Kosmotoga olearia TBF 19.5.1 7967462 YP_002940635.1 CDS Kole_0922 NC_012785.1 975211 976785 D PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; DbpA RNA-binding domain protein; SMART: DEAD-like helicase ; helicase domain protein; KEGG: dvm:DvMF_2125 DEAD/DEAH box helicase domain protein; DEAD/DEAH box helicase domain protein 975211..976785 Kosmotoga olearia TBF 19.5.1 7967463 YP_002940636.1 CDS Kole_0923 NC_012785.1 976787 977698 R KEGG: sat:SYN_02543 PAS sensory box/GGDEF family protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: GGDEF domain containing protein; PAS domain containing protein; diguanylate cyclase with PAS/PAC sensor complement(976787..977698) Kosmotoga olearia TBF 19.5.1 7967464 YP_002940637.1 CDS Kole_0924 NC_012785.1 978020 979105 D PFAM: NAD/NADP octopine/nopaline dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Ketopantoate reductase ApbA/PanE domain protein; KEGG: glo:Glov_2392 NAD/NADP octopine/nopaline dehydrogenase; NAD/NADP octopine/nopaline dehydrogenase 978020..979105 Kosmotoga olearia TBF 19.5.1 7967465 YP_002940638.1 CDS Kole_0925 NC_012785.1 979102 980739 D KEGG: dde:Dde_3086 hypothetical protein; hypothetical protein 979102..980739 Kosmotoga olearia TBF 19.5.1 7967466 YP_002940639.1 CDS Kole_0926 NC_012785.1 980753 981718 D PFAM: D-alanine--D-alanine ligase domain protein; protein of unknown function DUF201; phosphoribosylglycinamide synthetase; KEGG: ank:AnaeK_1410 D-alanine--D-alanine ligase; D-alanine--D-alanine ligase 980753..981718 Kosmotoga olearia TBF 19.5.1 7967467 YP_002940640.1 CDS Kole_0927 NC_012785.1 981698 982387 R hypothetical protein complement(981698..982387) Kosmotoga olearia TBF 19.5.1 7967468 YP_002940641.1 CDS Kole_0928 NC_012785.1 982435 983319 R PFAM: Patatin; KEGG: swp:swp_4746 patatin; Lysophospholipase complement(982435..983319) Kosmotoga olearia TBF 19.5.1 7967469 YP_002940642.1 CDS Kole_0929 NC_012785.1 983390 984232 R PFAM: GTP-binding protein HSR1-related; KEGG: bha:BH2476 hypothetical protein; GTP-binding protein HSR1-related complement(983390..984232) Kosmotoga olearia TBF 19.5.1 7967470 YP_002940643.1 CDS Kole_0930 NC_012785.1 984326 985126 R PFAM: beta-lactamase domain protein; KEGG: swd:Swoo_1375 beta-lactamase domain-containing protein; beta-lactamase domain protein complement(984326..985126) Kosmotoga olearia TBF 19.5.1 7967471 YP_002940644.1 CDS Kole_0931 NC_012785.1 985153 986352 R PFAM: major facilitator superfamily MFS_1; KEGG: sew:SeSA_A1649 major facilitator superfamily MFS_1; major facilitator superfamily MFS_1 complement(985153..986352) Kosmotoga olearia TBF 19.5.1 7967472 YP_002940645.1 CDS Kole_0932 NC_012785.1 986349 987338 R PFAM: ADP-ribosylation/Crystallin J1; KEGG: psb:Psyr_2921 ADP-ribosylglycohydrolase; ADP-ribosylation/Crystallin J1 complement(986349..987338) Kosmotoga olearia TBF 19.5.1 7967473 YP_002940646.1 CDS Kole_0933 NC_012785.1 987358 988416 R PFAM: Malate/L-lactate dehydrogenase; KEGG: sat:SYN_02526 malate/L-lactate dehydrogenase; Malate dehydrogenase complement(987358..988416) Kosmotoga olearia TBF 19.5.1 7967474 YP_002940647.1 CDS Kole_0934 NC_012785.1 988413 989399 R PFAM: diacylglycerol kinase catalytic region; diacylglycerol kinase catalytic region complement(988413..989399) Kosmotoga olearia TBF 19.5.1 7967475 YP_002940648.1 CDS Kole_0935 NC_012785.1 989396 990178 R PFAM: Xylose isomerase domain protein TIM barrel; KEGG: hap:HAPS_1868 hydroxypyruvate isomerase; Xylose isomerase domain protein TIM barrel complement(989396..990178) Kosmotoga olearia TBF 19.5.1 7967476 YP_002940649.1 CDS Kole_0936 NC_012785.1 990175 991404 R PFAM: extracellular solute-binding protein family 1; KEGG: bpa:BPP4347 extracellular solute-binding protein; extracellular solute-binding protein family 1 complement(990175..991404) Kosmotoga olearia TBF 19.5.1 7967477 YP_002940650.1 CDS Kole_0937 NC_012785.1 991430 992248 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ret:RHE_PF00301 sugar ABC transporter, permease protein; binding-protein-dependent transport systems inner membrane component complement(991430..992248) Kosmotoga olearia TBF 19.5.1 7967478 YP_002940651.1 CDS Kole_0938 NC_012785.1 992257 993144 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bha:BH1077 glycerol-3-phosphate ABC transporter (permease); binding-protein-dependent transport systems inner membrane component complement(992257..993144) Kosmotoga olearia TBF 19.5.1 7967479 YP_002940652.1 CDS Kole_0939 NC_012785.1 993128 994117 R PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: similar to predicted protein; Alcohol dehydrogenase GroES domain protein complement(993128..994117) Kosmotoga olearia TBF 19.5.1 7967480 YP_002940653.1 CDS Kole_0940 NC_012785.1 994114 995073 R PFAM: sugar-binding domain protein; KEGG: bha:BH0780 transcriptional regulator; DeoR family transcriptional regulator complement(994114..995073) Kosmotoga olearia TBF 19.5.1 7967481 YP_002940654.1 CDS Kole_0941 NC_012785.1 995117 995854 R PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: dvm:DvMF_1751 predicted phospho-2-dehydro-3-deoxyheptonate aldolase; Fructose-bisphosphate aldolase complement(995117..995854) Kosmotoga olearia TBF 19.5.1 7967482 YP_002940655.1 CDS Kole_0942 NC_012785.1 996130 996225 R hypothetical protein complement(996130..996225) Kosmotoga olearia TBF 19.5.1 7967483 YP_002940656.1 CDS Kole_0943 NC_012785.1 996675 997730 D hypothetical protein 996675..997730 Kosmotoga olearia TBF 19.5.1 7967484 YP_002940657.1 CDS Kole_0944 NC_012785.1 997777 998805 R TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; SUA5 domain protein; KEGG: bha:BH3771 hypothetical protein; Sua5/YciO/YrdC/YwlC family protein complement(997777..998805) Kosmotoga olearia TBF 19.5.1 7967485 YP_002940658.1 CDS Kole_0945 NC_012785.1 998802 1000565 R KEGG: dal:Dalk_0251 CoA-substrate-specific enzyme activase; TIGRFAM: CoA-substrate-specific enzyme activase; PFAM: ATPase BadF/BadG/BcrA/BcrD type; 2-hydroxyglutaryl-CoA dehydratase D-component; CoA-substrate-specific enzyme activase complement(998802..1000565) Kosmotoga olearia TBF 19.5.1 7967486 YP_002940659.1 CDS Kole_0946 NC_012785.1 1000570 1001826 R PFAM: 2-hydroxyglutaryl-CoA dehydratase D-component; KEGG: dal:Dalk_3223 2-hydroxyglutaryl-CoA dehydratase D-component; 2-hydroxyglutaryl-CoA dehydratase D-component complement(1000570..1001826) Kosmotoga olearia TBF 19.5.1 7967487 YP_002940660.1 CDS Kole_0947 NC_012785.1 1001977 1002942 D PFAM: metallophosphoesterase; KEGG: ecd:ECDH10B_0144 phosphatase; metallophosphoesterase 1001977..1002942 Kosmotoga olearia TBF 19.5.1 7967488 YP_002940661.1 CDS Kole_0948 NC_012785.1 1003021 1003257 D TIGRFAM: glutaredoxin-like protein, YruB-family; PFAM: glutaredoxin; KEGG: nis:NIS_1512 glutaredoxin; glutaredoxin-like protein, YruB-family 1003021..1003257 Kosmotoga olearia TBF 19.5.1 7967489 YP_002940662.1 CDS Kole_0949 NC_012785.1 1003351 1004313 D KEGG: gbm:Gbem_4017 galactose-1-phosphate uridylyltransferase; TIGRFAM: galactose-1-phosphate uridylyltransferase; PFAM: galactose-1-phosphate uridyl transferase domain protein; galactose-1-phosphate uridylyltransferase 1003351..1004313 Kosmotoga olearia TBF 19.5.1 7967490 YP_002940663.1 CDS Kole_0950 NC_012785.1 1004306 1005409 D TIGRFAM: galactokinase; PFAM: GHMP kinase; GHMP kinase domain protein; KEGG: ftn:FTN_0685 galactokinase; galactokinase 1004306..1005409 Kosmotoga olearia TBF 19.5.1 7967491 YP_002940664.1 CDS Kole_0951 NC_012785.1 1005562 1006623 D PFAM: basic membrane lipoprotein; KEGG: dps:DP0677 hypothetical protein; basic membrane lipoprotein 1005562..1006623 Kosmotoga olearia TBF 19.5.1 7967492 YP_002940665.1 CDS Kole_0952 NC_012785.1 1006634 1008544 D PFAM: inner-membrane translocator; KEGG: dat:HRM2_06330 RbsC1; inner-membrane translocator 1006634..1008544 Kosmotoga olearia TBF 19.5.1 7967493 YP_002940666.1 CDS Kole_0953 NC_012785.1 1008537 1009469 D PFAM: inner-membrane translocator; KEGG: mmw:Mmwyl1_1924 inner-membrane translocator; inner-membrane translocator 1008537..1009469 Kosmotoga olearia TBF 19.5.1 7967494 YP_002940667.1 CDS Kole_0954 NC_012785.1 1009471 1010964 D PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: baa:BA_4398 simple sugar transport system ATP-binding protein; ABC transporter 1009471..1010964 Kosmotoga olearia TBF 19.5.1 7967657 YP_002940668.1 CDS Kole_0955 NC_012785.1 1010977 1011423 D PFAM: PspC domain protein; KEGG: bar:GBAA4739 hypothetical protein; phage shock protein C, PspC 1010977..1011423 Kosmotoga olearia TBF 19.5.1 7967658 YP_002940669.1 CDS Kole_0956 NC_012785.1 1011429 1012322 D hypothetical protein 1011429..1012322 Kosmotoga olearia TBF 19.5.1 7967659 YP_002940670.1 CDS Kole_0958 NC_012785.1 1013241 1014029 R PFAM: cobalamin B12-binding domain protein; KEGG: rfr:Rfer_3887 cobalamin B12-binding; cobalamin B12-binding domain protein complement(1013241..1014029) Kosmotoga olearia TBF 19.5.1 7967661 YP_002940671.1 CDS Kole_0959 NC_012785.1 1014026 1015585 R PFAM: D-Lysine 56-aminomutase alpha subunit; KEGG: rfr:Rfer_3888 D-lysine 5,6-aminomutase alpha subunit; D-Lysine 56-aminomutase alpha subunit complement(1014026..1015585) Kosmotoga olearia TBF 19.5.1 7967662 YP_002940672.1 CDS Kole_0960 NC_012785.1 1015627 1017048 R PFAM: DNA mismatch repair protein MutS domain protein; SMART: DNA mismatch repair protein MutS domain protein; KEGG: aca:ACP_2271 MutS2 family protein; DNA mismatch repair protein MutS domain protein complement(1015627..1017048) Kosmotoga olearia TBF 19.5.1 7967663 YP_002940673.1 CDS Kole_0961 NC_012785.1 1017045 1018073 R KEGG: rfr:Rfer_3889 hypothetical protein; hypothetical protein complement(1017045..1018073) Kosmotoga olearia TBF 19.5.1 7967664 YP_002940674.1 CDS Kole_0962 NC_012785.1 1018096 1018515 R PFAM: MaoC domain protein dehydratase; KEGG: psa:PST_2962 enoyl-CoA hydratase, R-specific; MaoC domain protein dehydratase complement(1018096..1018515) Kosmotoga olearia TBF 19.5.1 7967665 YP_002940675.1 CDS Kole_0963 NC_012785.1 1018499 1019779 R KEGG: baa:BA_2804 lysine 2,3-aminomutase; TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: Radical SAM domain protein; lysine 2,3-aminomutase YodO family protein complement(1018499..1019779) Kosmotoga olearia TBF 19.5.1 7967666 YP_002940676.1 CDS Kole_0964 NC_012785.1 1019837 1020871 R KEGG: rfr:Rfer_3890 zinc-binding alcohol dehydrogenase; zinc-binding alcohol dehydrogenase complement(1019837..1020871) Kosmotoga olearia TBF 19.5.1 7967667 YP_002940677.1 CDS Kole_0965 NC_012785.1 1020877 1021701 R PFAM: protein of unknown function DUF849; KEGG: rfr:Rfer_3885 hypothetical protein; hypothetical protein complement(1020877..1021701) Kosmotoga olearia TBF 19.5.1 7967668 YP_002940678.1 CDS Kole_0966 NC_012785.1 1021694 1022086 R PFAM: thioesterase superfamily protein; KEGG: mxa:MXAN_4385 beta-alanyl-CoA:ammonia lyase; thioesterase superfamily protein complement(1021694..1022086) Kosmotoga olearia TBF 19.5.1 7967669 YP_002940679.1 CDS Kole_0967 NC_012785.1 1022299 1022901 D PFAM: Methyltransferase type 11; UbiE/COQ5 methyltransferase; Methyltransferase type 12; KEGG: ajs:Ajs_2160 methyltransferase type 11; Methyltransferase type 11 1022299..1022901 Kosmotoga olearia TBF 19.5.1 7967670 YP_002940680.1 CDS fabZ NC_012785.1 1022921 1023340 R in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase complement(1022921..1023340) Kosmotoga olearia TBF 19.5.1 7967671 YP_002940681.1 CDS Kole_0969 NC_012785.1 1023525 1024505 D KEGG: baa:BA_1722 chalcone and stilbene synthases, C-terminal domain; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; 3-oxoacyl-ACP synthase III 1023525..1024505 Kosmotoga olearia TBF 19.5.1 7967672 YP_002940682.1 CDS Kole_0970 NC_012785.1 1024472 1025422 D TIGRFAM: enoyl-(acyl-carrier-protein) reductase II; PFAM: 2-nitropropane dioxygenase NPD; KEGG: oxidoreductase, 2-nitropropane dioxygenase family protein ; K02371 enoyl-; enoyl-ACP reductase II 1024472..1025422 Kosmotoga olearia TBF 19.5.1 7967673 YP_002940683.1 CDS Kole_0971 NC_012785.1 1025419 1026351 D TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: pca:Pcar_1437 malonyl CoA-acyl carrier protein transacylase; malonyl CoA-acyl carrier protein transacylase 1025419..1026351 Kosmotoga olearia TBF 19.5.1 7967674 YP_002940684.1 CDS Kole_0972 NC_012785.1 1026453 1026683 D TIGRFAM: acyl carrier protein; PFAM: phosphopantetheine-binding; KEGG: afw:Anae109_2736 acyl carrier protein; acyl carrier protein 1026453..1026683 Kosmotoga olearia TBF 19.5.1 7967675 YP_002940685.1 CDS Kole_0973 NC_012785.1 1026689 1027915 D TIGRFAM: 3-oxoacyl-[acyl-carrier-protein] synthase 2; PFAM: Beta-ketoacyl synthase; KEGG: gsu:GSU1605 3-oxoacyl-(acyl-carrier-protein) synthase II; 3-oxoacyl-ACP synthase II 1026689..1027915 Kosmotoga olearia TBF 19.5.1 7967676 YP_002940686.1 CDS Kole_0974 NC_012785.1 1028099 1028380 D KEGG: pca:Pcar_2756 hypothetical protein; hypothetical protein 1028099..1028380 Kosmotoga olearia TBF 19.5.1 7967677 YP_002940687.1 CDS Kole_0975 NC_012785.1 1028435 1030465 D PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A; KEGG: hypothetical protein; von Willebrand factor type A 1028435..1030465 Kosmotoga olearia TBF 19.5.1 7967678 YP_002940688.1 CDS Kole_0976 NC_012785.1 1031095 1032021 R KEGG: rlt:Rleg2_6232 hypothetical protein; hypothetical protein complement(1031095..1032021) Kosmotoga olearia TBF 19.5.1 7967679 YP_002940689.1 CDS Kole_0977 NC_012785.1 1032040 1033197 R PFAM: peptidase M24; KEGG: bha:BH0491 hypothetical protein; peptidase M24 complement(1032040..1033197) Kosmotoga olearia TBF 19.5.1 7967680 YP_002940690.1 CDS Kole_0978 NC_012785.1 1033356 1033721 R KEGG: bha:BH0491 hypothetical protein; hypothetical protein complement(1033356..1033721) Kosmotoga olearia TBF 19.5.1 7967681 YP_002940691.1 CDS Kole_0979 NC_012785.1 1033873 1034919 R PFAM: glycosidase PH1107-related; KEGG: sat:SYN_01903 cytoplasmic protein; glycosidase PH1107-related complement(1033873..1034919) Kosmotoga olearia TBF 19.5.1 7967682 YP_002940692.1 CDS Kole_0980 NC_012785.1 1034942 1035817 R KEGG: sus:Acid_0995 hypothetical protein; hypothetical protein complement(1034942..1035817) Kosmotoga olearia TBF 19.5.1 7967683 YP_002940693.1 CDS Kole_0981 NC_012785.1 1035847 1036677 R KEGG: hypothetical protein; hypothetical protein complement(1035847..1036677) Kosmotoga olearia TBF 19.5.1 7967684 YP_002940694.1 CDS Kole_0982 NC_012785.1 1036705 1037577 R PFAM: Xylose isomerase domain protein TIM barrel; KEGG: ara:Arad_14120 myo-inositol catabolism protein; Xylose isomerase domain protein TIM barrel complement(1036705..1037577) Kosmotoga olearia TBF 19.5.1 7967685 YP_002940695.1 CDS Kole_0983 NC_012785.1 1037626 1038726 R PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: ade:Adeh_4137 ABC transporter, ATPase subunit; ABC transporter complement(1037626..1038726) Kosmotoga olearia TBF 19.5.1 7967686 YP_002940696.1 CDS Kole_0984 NC_012785.1 1038744 1039619 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ret:RHE_PB00137 sugar ABC transporter, permease protein; binding-protein-dependent transport systems inner membrane component complement(1038744..1039619) Kosmotoga olearia TBF 19.5.1 7967687 YP_002940697.1 CDS Kole_0985 NC_012785.1 1039616 1040572 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: avi:Avi_5252 ABC transporter membrane spanning protein (sugar); binding-protein-dependent transport systems inner membrane component complement(1039616..1040572) Kosmotoga olearia TBF 19.5.1 7967688 YP_002940698.1 CDS Kole_0986 NC_012785.1 1040658 1042010 R PFAM: extracellular solute-binding protein family 1; KEGG: atc:AGR_L_1296 multiple sugar transport system substrate-binding protein; extracellular solute-binding protein family 1 complement(1040658..1042010) Kosmotoga olearia TBF 19.5.1 7967689 YP_002940699.1 CDS Kole_0987 NC_012785.1 1042211 1043248 R PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: hap:HAPS_1534 myoinositol 2-dehydrogenase with oxidoreductase domain; oxidoreductase domain protein complement(1042211..1043248) Kosmotoga olearia TBF 19.5.1 7967690 YP_002940700.1 CDS Kole_0988 NC_012785.1 1043261 1044157 R PFAM: Xylose isomerase domain protein TIM barrel; KEGG: hap:HAPS_1533 myoinositol catabolism protein with xylose isomerase domain (2-keto-myo-inositol dehydratase); Myo-inosose-2 dehydratase complement(1043261..1044157) Kosmotoga olearia TBF 19.5.1 7967691 YP_002940701.1 CDS Kole_0989 NC_012785.1 1044174 1046045 R PFAM: thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein TPP binding domain protein; KEGG: baa:BA_3005 thiamine pyrophosphate enzyme, C-terminal TPP binding domain; thiamine pyrophosphate protein central region complement(1044174..1046045) Kosmotoga olearia TBF 19.5.1 7967692 YP_002940702.1 CDS Kole_0990 NC_012785.1 1046049 1046846 R PFAM: Myo-inositol catabolism IolB domain protein; KEGG: baa:BA_3009 hypothetical protein predicted by GeneMark; Myo-inositol catabolism IolB domain protein complement(1046049..1046846) Kosmotoga olearia TBF 19.5.1 7967693 YP_002940703.1 CDS Kole_0991 NC_012785.1 1046869 1047936 R KEGG: mmw:Mmwyl1_3080 tartrate dehydrogenase; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase; tartrate dehydrogenase complement(1046869..1047936) Kosmotoga olearia TBF 19.5.1 7967694 YP_002940704.1 CDS Kole_0992 NC_012785.1 1047936 1048913 R PFAM: Transketolase domain protein; Transketolase central region; KEGG: efe:EFER_0870 carbohydrate degradation enzyme; Transketolase domain protein complement(1047936..1048913) Kosmotoga olearia TBF 19.5.1 7967695 YP_002940705.1 CDS Kole_0993 NC_012785.1 1048910 1049764 R PFAM: Transketolase domain protein; KEGG: efe:EFER_0869 carbohydrate degradation enzyme; Transketolase domain protein complement(1048910..1049764) Kosmotoga olearia TBF 19.5.1 7967696 YP_002940706.1 CDS Kole_0994 NC_012785.1 1049768 1051033 R KEGG: gbm:Gbem_0565 hypothetical protein; hypothetical protein complement(1049768..1051033) Kosmotoga olearia TBF 19.5.1 7967697 YP_002940707.1 CDS Kole_0995 NC_012785.1 1051030 1052295 R PFAM: phosphoglycerate kinase; KEGG: scl:sce7349 phosphoglycerate kinase; Phosphoglycerate kinase complement(1051030..1052295) Kosmotoga olearia TBF 19.5.1 7967698 YP_002940708.1 CDS Kole_0996 NC_012785.1 1052301 1053317 R KEGG: ajs:Ajs_2680 glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type II; PFAM: glyceraldehyde 3-phosphate dehydrogenase; dihydrodipicolinate reductase; glyceraldehyde-3-phosphate dehydrogenase, type II complement(1052301..1053317) Kosmotoga olearia TBF 19.5.1 7967699 YP_002940709.1 CDS Kole_0997 NC_012785.1 1053334 1054323 R PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: hiq:CGSHiGG_05790 ribokinase; LacI family transcriptional regulator complement(1053334..1054323) Kosmotoga olearia TBF 19.5.1 7967700 YP_002940710.1 CDS Kole_0998 NC_012785.1 1055252 1056352 D PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: cko:CKO_02994 hypothetical protein; UBA/THIF-type NAD/FAD binding protein 1055252..1056352 Kosmotoga olearia TBF 19.5.1 7967702 YP_002940711.1 CDS Kole_0999 NC_012785.1 1056333 1056521 D hypothetical protein 1056333..1056521 Kosmotoga olearia TBF 19.5.1 7967703 YP_002940712.1 CDS Kole_1000 NC_012785.1 1056671 1058002 D KEGG: aba:Acid345_1818 hypothetical protein; hypothetical protein 1056671..1058002 Kosmotoga olearia TBF 19.5.1 7967704 YP_002940713.1 CDS Kole_1001 NC_012785.1 1058071 1058805 R PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase; KEGG: tcx:Tcr_1069 protein-L-isoaspartate O-methyltransferase; Protein-L-isoaspartate(D-aspartate) O-methyltransferase complement(1058071..1058805) Kosmotoga olearia TBF 19.5.1 7967705 YP_002940714.1 CDS Kole_1002 NC_012785.1 1059539 1061239 R KEGG: sbn:Sbal195_1477 metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; Metal-dependent hydrolase HDOD; SMART: metal-dependent phosphohydrolase HD region; metal dependent phosphohydrolase complement(1059539..1061239) Kosmotoga olearia TBF 19.5.1 7967706 YP_002940715.1 CDS Kole_1003 NC_012785.1 1061507 1062841 R PFAM: peptidase U62 modulator of DNA gyrase; KEGG: aca:ACP_2625 TldD/PmbA family protein; peptidase U62 modulator of DNA gyrase complement(1061507..1062841) Kosmotoga olearia TBF 19.5.1 7967707 YP_002940716.1 CDS Kole_1004 NC_012785.1 1062838 1064229 R PFAM: peptidase U62 modulator of DNA gyrase; KEGG: sil:SPO3077 TldD/PmbA family protein; peptidase U62 modulator of DNA gyrase complement(1062838..1064229) Kosmotoga olearia TBF 19.5.1 7967708 YP_002940717.1 CDS Kole_1005 NC_012785.1 1064345 1064941 D PFAM: beta-lactamase domain protein; KEGG: metallo-beta-lactamase superfamily protein; beta-lactamase domain protein 1064345..1064941 Kosmotoga olearia TBF 19.5.1 7967709 YP_002940718.1 CDS Kole_1006 NC_012785.1 1064942 1066264 R KEGG: pap:PSPA7_5383 hypothetical protein; hypothetical protein complement(1064942..1066264) Kosmotoga olearia TBF 19.5.1 7967710 YP_002940719.1 CDS Kole_1007 NC_012785.1 1066273 1067037 R PFAM: protein of unknown function DUF218; KEGG: nmu:Nmul_A0343 hypothetical protein; hypothetical protein complement(1066273..1067037) Kosmotoga olearia TBF 19.5.1 7967711 YP_002940720.1 CDS Kole_1008 NC_012785.1 1067048 1067770 R PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: nis:NIS_0508 glycerophosphoryl diester phosphodiesterase; glycerophosphoryl diester phosphodiesterase complement(1067048..1067770) Kosmotoga olearia TBF 19.5.1 7967712 YP_002940721.1 CDS Kole_1009 NC_012785.1 1067763 1068014 R hypothetical protein complement(1067763..1068014) Kosmotoga olearia TBF 19.5.1 7967713 YP_002940722.1 CDS Kole_1011 NC_012785.1 1070305 1071447 D PFAM: FAD dependent oxidoreductase; KEGG: ank:AnaeK_1379 FAD dependent oxidoreductase; FAD dependent oxidoreductase 1070305..1071447 Kosmotoga olearia TBF 19.5.1 7967715 YP_002940723.1 CDS Kole_1012 NC_012785.1 1071460 1073037 D TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: Aldehyde Dehydrogenase; KEGG: aca:ACP_2709 delta-1-pyrroline-5-carboxylate dehydrogenase; delta-1-pyrroline-5-carboxylate dehydrogenase 1071460..1073037 Kosmotoga olearia TBF 19.5.1 7967716 YP_002940724.1 CDS Kole_1013 NC_012785.1 1073098 1073523 R KEGG: hypothetical LOC100001051; hypothetical protein complement(1073098..1073523) Kosmotoga olearia TBF 19.5.1 7967717 YP_002940725.1 CDS Kole_1014 NC_012785.1 1074120 1075349 D PFAM: phosphofructokinase; KEGG: noc:Noc_2846 6-phosphofructokinase; phosphofructokinase 1074120..1075349 Kosmotoga olearia TBF 19.5.1 7967718 YP_002940726.1 CDS Kole_1015 NC_012785.1 1075393 1076490 R KEGG: dal:Dalk_4664 response regulator receiver modulated metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; response regulator receiver; Metal-dependent hydrolase HDOD; SMART: response regulator receiver; metal-dependent phosphohydrolase HD region; response regulator receiver modulated metal dependent phosphohydrolase complement(1075393..1076490) Kosmotoga olearia TBF 19.5.1 7967719 YP_002940727.1 CDS Kole_1016 NC_012785.1 1076471 1076875 R PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: dal:Dalk_1601 response regulator receiver protein; response regulator receiver protein complement(1076471..1076875) Kosmotoga olearia TBF 19.5.1 7967720 YP_002940728.1 CDS Kole_1017 NC_012785.1 1076847 1078463 R PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: ppd:Ppro_2725 PAS/PAC sensor signal transduction histidine kinase; histidine kinase complement(1076847..1078463) Kosmotoga olearia TBF 19.5.1 7967721 YP_002940729.1 CDS Kole_1018 NC_012785.1 1079018 1080487 D PFAM: Integrase catalytic region; KEGG: gur:Gura_2875 integrase catalytic subunit; Integrase catalytic region 1079018..1080487 Kosmotoga olearia TBF 19.5.1 7967722 YP_002940730.1 CDS Kole_1019 NC_012785.1 1080495 1081217 D PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: atc:AGR_L_50 hypothetical protein; IstB domain protein ATP-binding protein 1080495..1081217 Kosmotoga olearia TBF 19.5.1 7967723 YP_002940731.1 CDS Kole_1020 NC_012785.1 1081344 1082444 R SMART: regulatory protein ArsR; KEGG: dde:Dde_0747 ArsR family transcriptional regulator; ArsR family transcriptional regulator complement(1081344..1082444) Kosmotoga olearia TBF 19.5.1 7967724 YP_002940732.1 CDS Kole_1021 NC_012785.1 1082538 1083929 R TIGRFAM: dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: bsu:BSU29980 dipeptidase PepV; dipeptidase complement(1082538..1083929) Kosmotoga olearia TBF 19.5.1 7967725 YP_002940733.1 CDS Kole_1022 NC_012785.1 1083926 1084948 R PFAM: Nucleotidyl transferase; KEGG: sat:SYN_01031 mannose-1-phosphate guanylyltransferase; Mannose-1-phosphate guanylyltransferase complement(1083926..1084948) Kosmotoga olearia TBF 19.5.1 7967726 YP_002940734.1 CDS Kole_1023 NC_012785.1 1085028 1086761 D KEGG: afw:Anae109_2240 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; SMART: GGDEF domain containing protein; diguanylate cyclase with GAF sensor 1085028..1086761 Kosmotoga olearia TBF 19.5.1 7967727 YP_002940735.1 CDS Kole_1024 NC_012785.1 1086758 1088209 R PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: dat:HRM2_37390 predicted two-component system transcriptional regulator; metal dependent phosphohydrolase complement(1086758..1088209) Kosmotoga olearia TBF 19.5.1 7967728 YP_002940736.1 CDS Kole_1025 NC_012785.1 1088190 1089227 R hypothetical protein complement(1088190..1089227) Kosmotoga olearia TBF 19.5.1 7967729 YP_002940737.1 CDS Kole_1026 NC_012785.1 1089985 1090233 R KEGG: sat:SYN_02132 transcriptional regulator; transcriptional regulator complement(1089985..1090233) Kosmotoga olearia TBF 19.5.1 7967730 YP_002940738.1 CDS Kole_1027 NC_012785.1 1090341 1093433 D KEGG: baa:BA_1688 UvrD-helicase, UvrD/REP helicase; ATP-dependent nuclease subunit B-like protein 1090341..1093433 Kosmotoga olearia TBF 19.5.1 7967731 YP_002940739.1 CDS Kole_1028 NC_012785.1 1093376 1096351 D PFAM: UvrD/REP helicase; KEGG: sfu:Sfum_0502 UvrD/REP helicase; Exodeoxyribonuclease V 1093376..1096351 Kosmotoga olearia TBF 19.5.1 7967732 YP_002940740.1 CDS Kole_1029 NC_012785.1 1096354 1097112 D PFAM: membrane-flanked domain; KEGG: scl:sce0976 hypothetical protein; membrane-flanked domain protein 1096354..1097112 Kosmotoga olearia TBF 19.5.1 7967733 YP_002940741.1 CDS Kole_1030 NC_012785.1 1097214 1097909 R PFAM: Abortive infection protein; KEGG: sdn:Sden_1909 abortive infection protein; Abortive infection protein complement(1097214..1097909) Kosmotoga olearia TBF 19.5.1 7967734 YP_002940742.1 CDS Kole_1031 NC_012785.1 1097911 1098402 R PFAM: transcriptional regulator PadR family protein; KEGG: dat:HRM2_38900 transcriptional regulator (PadR family protein); PadR family transcriptional regulator complement(1097911..1098402) Kosmotoga olearia TBF 19.5.1 7967735 YP_002940743.1 CDS Kole_1033 NC_012785.1 1099399 1100556 R hypothetical protein complement(1099399..1100556) Kosmotoga olearia TBF 19.5.1 7967737 YP_002940744.1 CDS Kole_1034 NC_012785.1 1100587 1101948 R KEGG: scl:sce4297 Beta-glucosidase; TIGRFAM: beta-galactosidase; PFAM: glycoside hydrolase family 1; beta-galactosidase complement(1100587..1101948) Kosmotoga olearia TBF 19.5.1 7967981 YP_002940745.1 CDS Kole_1035 NC_012785.1 1101941 1103104 R PFAM: glycosyl transferase group 1; KEGG: bsu:BSU30910 spore coat protein; glycosyl transferase group 1 complement(1101941..1103104) Kosmotoga olearia TBF 19.5.1 7967982 YP_002940746.1 CDS Kole_1036 NC_012785.1 1103114 1103941 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bha:BH1866 sugar transport system (permease) (binding protein dependent transporter); binding-protein-dependent transport systems inner membrane component complement(1103114..1103941) Kosmotoga olearia TBF 19.5.1 7967983 YP_002940747.1 CDS Kole_1037 NC_012785.1 1103951 1104823 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: scl:sce3058 sugar ABC transporter, permease protein; binding-protein-dependent transport systems inner membrane component complement(1103951..1104823) Kosmotoga olearia TBF 19.5.1 7967984 YP_002940748.1 CDS Kole_1038 NC_012785.1 1104899 1106185 R PFAM: extracellular solute-binding protein family 1; KEGG: bha:BH1864 hypothetical protein; extracellular solute-binding protein family 1 complement(1104899..1106185) Kosmotoga olearia TBF 19.5.1 7967985 YP_002940749.1 CDS Kole_1039 NC_012785.1 1106211 1106876 R TIGRFAM: beta-phosphoglucomutase; beta-phosphoglucomutase family hydrolase; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: pmr:PMI0289 beta-phosphoglucomutase; beta-phosphoglucomutase complement(1106211..1106876) Kosmotoga olearia TBF 19.5.1 7967986 YP_002940750.1 CDS Kole_1040 NC_012785.1 1106899 1107909 R PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: bar:GBAA0664 ribose operon repressor; LacI family transcriptional regulator complement(1106899..1107909) Kosmotoga olearia TBF 19.5.1 7967987 YP_002940751.1 CDS Kole_1041 NC_012785.1 1108053 1109282 R PFAM: major facilitator superfamily MFS_1; KEGG: ppr:PBPRA2340 transport protein; major facilitator superfamily MFS_1 complement(1108053..1109282) Kosmotoga olearia TBF 19.5.1 7967988 YP_002940752.1 CDS Kole_1042 NC_012785.1 1109933 1110046 D hypothetical protein 1109933..1110046 Kosmotoga olearia TBF 19.5.1 7967989 YP_002940753.1 CDS Kole_1043 NC_012785.1 1110203 1111474 D PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron maturase-specific domain protein; KEGG: amc:MADE_01366 hypothetical maturase; RNA-directed DNA polymerase (Reverse transcriptase) 1110203..1111474 Kosmotoga olearia TBF 19.5.1 7967990 YP_002940754.1 CDS Kole_1044 NC_012785.1 1111603 1112817 D PFAM: transposase mutator type; KEGG: par:Psyc_0534 transposase mutator family protein; transposase mutator type 1111603..1112817 Kosmotoga olearia TBF 19.5.1 7967991 YP_002940755.1 CDS Kole_1045 NC_012785.1 1113249 1114400 D PFAM: protein of unknown function UPF0027; KEGG: net:Neut_0880 hypothetical protein; hypothetical protein 1113249..1114400 Kosmotoga olearia TBF 19.5.1 7967992 YP_002940756.1 CDS Kole_1047 NC_012785.1 1115879 1116601 R PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: atc:AGR_L_50 hypothetical protein; IstB domain protein ATP-binding protein complement(1115879..1116601) Kosmotoga olearia TBF 19.5.1 7967994 YP_002940757.1 CDS Kole_1048 NC_012785.1 1116609 1118078 R PFAM: Integrase catalytic region; KEGG: gur:Gura_2875 integrase catalytic subunit; Integrase catalytic region complement(1116609..1118078) Kosmotoga olearia TBF 19.5.1 7967995 YP_002940758.1 CDS Kole_1049 NC_012785.1 1118162 1118842 R hypothetical protein complement(1118162..1118842) Kosmotoga olearia TBF 19.5.1 7967996 YP_002940759.1 CDS Kole_1050 NC_012785.1 1119082 1120491 R PFAM: Radical SAM domain protein; KEGG: gur:Gura_3559 radical SAM domain-containing protein; Radical SAM domain protein complement(1119082..1120491) Kosmotoga olearia TBF 19.5.1 7967997 YP_002940760.1 CDS Kole_1051 NC_012785.1 1120679 1121401 R PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: atc:AGR_L_50 hypothetical protein; IstB domain protein ATP-binding protein complement(1120679..1121401) Kosmotoga olearia TBF 19.5.1 7967998 YP_002940761.1 CDS Kole_1052 NC_012785.1 1121409 1122878 R PFAM: Integrase catalytic region; KEGG: gur:Gura_2875 integrase catalytic subunit; Integrase catalytic region complement(1121409..1122878) Kosmotoga olearia TBF 19.5.1 7967999 YP_002940762.1 CDS Kole_1054 NC_012785.1 1123385 1123723 R hypothetical protein complement(1123385..1123723) Kosmotoga olearia TBF 19.5.1 7968001 YP_002940763.1 CDS Kole_1056 NC_012785.1 1124104 1125021 R KEGG: tdn:Suden_1026 periplasmic copper-binding; hypothetical protein complement(1124104..1125021) Kosmotoga olearia TBF 19.5.1 7968003 YP_002940764.1 CDS Kole_1057 NC_012785.1 1125040 1125471 R KEGG: hypothetical protein; hypothetical protein complement(1125040..1125471) Kosmotoga olearia TBF 19.5.1 7968004 YP_002940765.1 CDS Kole_1058 NC_012785.1 1126064 1127725 D KEGG: im:7151086; si:ch211-250g4.3 ; K11498 centromeric protein E; hypothetical protein 1126064..1127725 Kosmotoga olearia TBF 19.5.1 7968005 YP_002940766.1 CDS Kole_1059 NC_012785.1 1128005 1128238 D hypothetical protein 1128005..1128238 Kosmotoga olearia TBF 19.5.1 7968006 YP_002940767.1 CDS Kole_1060 NC_012785.1 1128235 1128471 D PFAM: plasmid stabilization system; KEGG: noc:Noc_0433 hypothetical protein; plasmid stabilization system 1128235..1128471 Kosmotoga olearia TBF 19.5.1 7968007 YP_002940768.1 CDS Kole_1061 NC_012785.1 1128855 1130045 R PFAM: Pyrrolo-quinoline quinone; SMART: Pyrrolo-quinoline quinone; KEGG: csa:Csal_2857 pyrrolo-quinoline quinone; Pyrrolo-quinoline quinone complement(1128855..1130045) Kosmotoga olearia TBF 19.5.1 7968008 YP_002940769.1 CDS Kole_1062 NC_012785.1 1130083 1131123 R KEGG: pol:Bpro_4221 lipase transmembrane protein; hypothetical protein complement(1130083..1131123) Kosmotoga olearia TBF 19.5.1 7968009 YP_002940770.1 CDS Kole_1063 NC_012785.1 1131313 1132056 R hypothetical protein complement(1131313..1132056) Kosmotoga olearia TBF 19.5.1 7968010 YP_002940771.1 CDS Kole_1064 NC_012785.1 1132077 1132298 R hypothetical protein complement(1132077..1132298) Kosmotoga olearia TBF 19.5.1 7968011 YP_002940772.1 CDS Kole_1065 NC_012785.1 1132457 1134037 D KEGG: hypothetical protein; hypothetical protein 1132457..1134037 Kosmotoga olearia TBF 19.5.1 7968012 YP_002940773.1 CDS Kole_1066 NC_012785.1 1134446 1135216 R PFAM: short-chain dehydrogenase/reductase SDR; KEGG: smd:Smed_5220 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR complement(1134446..1135216) Kosmotoga olearia TBF 19.5.1 7968013 YP_002940774.1 CDS Kole_1067 NC_012785.1 1135408 1136610 D PFAM: major facilitator superfamily MFS_1; KEGG: nam:NAMH_0796 major facilitator superfamily MFS_1; major facilitator superfamily MFS_1 1135408..1136610 Kosmotoga olearia TBF 19.5.1 7968014 YP_002940775.1 CDS Kole_1068 NC_012785.1 1136932 1137255 D KEGG: bha:BH2593 hypothetical protein; hypothetical protein 1136932..1137255 Kosmotoga olearia TBF 19.5.1 7968015 YP_002940776.1 CDS Kole_1069 NC_012785.1 1137383 1138825 R PFAM: glycosyl transferase group 1; KEGG: nmu:Nmul_A2267 sucrose-phosphate phosphatase; Sucrose-phosphate synthase complement(1137383..1138825) Kosmotoga olearia TBF 19.5.1 7968016 YP_002940777.1 CDS Kole_1070 NC_012785.1 1138822 1139754 R PFAM: PfkB domain protein; KEGG: bar:GBAA0752 fructokinase; PfkB domain protein complement(1138822..1139754) Kosmotoga olearia TBF 19.5.1 7968017 YP_002940778.1 CDS Kole_1071 NC_012785.1 1139772 1140626 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pna:Pnap_0230 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component complement(1139772..1140626) Kosmotoga olearia TBF 19.5.1 7968018 YP_002940779.1 CDS Kole_1072 NC_012785.1 1140628 1141527 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pna:Pnap_0229 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component complement(1140628..1141527) Kosmotoga olearia TBF 19.5.1 7968019 YP_002940780.1 CDS Kole_1073 NC_012785.1 1141612 1142874 R PFAM: extracellular solute-binding protein family 1; KEGG: pna:Pnap_0227 extracellular solute-binding protein; extracellular solute-binding protein family 1 complement(1141612..1142874) Kosmotoga olearia TBF 19.5.1 7968020 YP_002940781.1 CDS Kole_1074 NC_012785.1 1142914 1143723 R PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; SMART: regulatory protein DeoR; KEGG: bha:BH1553 DeoR family transcriptional regulator; DeoR family transcriptional regulator complement(1142914..1143723) Kosmotoga olearia TBF 19.5.1 7968021 YP_002940782.1 CDS Kole_1075 NC_012785.1 1144145 1145050 R KEGG: mxa:MXAN_1978 hypothetical protein; hypothetical protein complement(1144145..1145050) Kosmotoga olearia TBF 19.5.1 7968022 YP_002940783.1 CDS Kole_1076 NC_012785.1 1145054 1145950 R PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: xfm:Xfasm12_1602 pantothenase; Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase complement(1145054..1145950) Kosmotoga olearia TBF 19.5.1 7968023 YP_002940784.1 CDS Kole_1077 NC_012785.1 1146118 1147794 D PFAM: zinc finger SWIM domain protein; KEGG: pca:Pcar_0899 hypothetical protein; zinc finger SWIM domain protein 1146118..1147794 Kosmotoga olearia TBF 19.5.1 7968024 YP_002940785.1 CDS Kole_1078 NC_012785.1 1147903 1148640 D PFAM: Radical SAM domain protein; KEGG: ppd:Ppro_0182 radical SAM domain-containing protein; Radical SAM domain protein 1147903..1148640 Kosmotoga olearia TBF 19.5.1 7968025 YP_002940786.1 CDS Kole_1080 NC_012785.1 1149032 1150327 R KEGG: noc:Noc_1356 hypothetical protein; hypothetical protein complement(1149032..1150327) Kosmotoga olearia TBF 19.5.1 7968027 YP_002940787.1 CDS Kole_1081 NC_012785.1 1150417 1151481 R PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dol:Dole_2297 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein complement(1150417..1151481) Kosmotoga olearia TBF 19.5.1 7968028 YP_002940788.1 CDS Kole_1082 NC_012785.1 1151494 1151946 R PFAM: flavin reductase domain protein FMN-binding; KEGG: sat:SYN_02123 ferric-chelate reductase / rubredoxin; flavin reductase domain protein FMN-binding complement(1151494..1151946) Kosmotoga olearia TBF 19.5.1 7968029 YP_002940789.1 CDS Kole_1083 NC_012785.1 1152184 1154619 D TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper ion binding protein; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; KEGG: dde:Dde_1313 heavy metal translocating P-type ATPase; heavy metal translocating P-type ATPase 1152184..1154619 Kosmotoga olearia TBF 19.5.1 7968030 YP_002940790.1 CDS Kole_1084 NC_012785.1 1154655 1154861 D PFAM: Heavy metal transport/detoxification protein; KEGG: bmj:BMULJ_05226 Cu2+-exporting ATPase; Heavy metal transport/detoxification protein 1154655..1154861 Kosmotoga olearia TBF 19.5.1 7968031 YP_002940791.1 CDS Kole_1085 NC_012785.1 1154894 1155181 D PFAM: protein of unknown function DUF156; KEGG: abu:Abu_0479 hypothetical protein; hypothetical protein 1154894..1155181 Kosmotoga olearia TBF 19.5.1 7968032 YP_002940792.1 CDS Kole_1086 NC_012785.1 1155329 1155832 D PFAM: GCN5-related N-acetyltransferase; KEGG: atc:AGR_C_3768 acetyltransferase; GCN5-related N-acetyltransferase 1155329..1155832 Kosmotoga olearia TBF 19.5.1 7968033 YP_002940793.1 CDS Kole_1087 NC_012785.1 1155883 1156293 D PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dde:Dde_2944 iron-sulfur cluster-binding protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein 1155883..1156293 Kosmotoga olearia TBF 19.5.1 7968034 YP_002940794.1 CDS Kole_1088 NC_012785.1 1156290 1158050 D KEGG: dvu:DVU0687 aldehyde:ferredoxin oxidoreductase, tungsten-containing, PFAM: Aldehyde ferredoxin oxidoreductase ; aldehyde ferredoxin oxidoreductase; SMART: Aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase 1156290..1158050 Kosmotoga olearia TBF 19.5.1 7968035 YP_002940795.1 CDS Kole_1089 NC_012785.1 1158116 1158808 R KEGG: similar to golgi autoantigen, golgin subfamily a, 4; hypothetical protein complement(1158116..1158808) Kosmotoga olearia TBF 19.5.1 7968036 YP_002940796.1 CDS Kole_1090 NC_012785.1 1158922 1159152 R hypothetical protein complement(1158922..1159152) Kosmotoga olearia TBF 19.5.1 7968037 YP_002940797.1 CDS Kole_1091 NC_012785.1 1159193 1159669 R hypothetical protein complement(1159193..1159669) Kosmotoga olearia TBF 19.5.1 7968038 YP_002940798.1 CDS Kole_1092 NC_012785.1 1159683 1160546 R hypothetical protein complement(1159683..1160546) Kosmotoga olearia TBF 19.5.1 7968039 YP_002940799.1 CDS Kole_1093 NC_012785.1 1160543 1161736 R KEGG: glo:Glov_0986 hypothetical protein; hypothetical protein complement(1160543..1161736) Kosmotoga olearia TBF 19.5.1 7968040 YP_002940800.1 CDS Kole_1094 NC_012785.1 1161738 1162826 R PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: dde:Dde_0483 ATPase; ATPase associated with various cellular activities AAA_3 complement(1161738..1162826) Kosmotoga olearia TBF 19.5.1 7968041 YP_002940801.1 CDS Kole_1095 NC_012785.1 1162894 1163610 R hypothetical protein complement(1162894..1163610) Kosmotoga olearia TBF 19.5.1 7968042 YP_002940802.1 CDS Kole_1096 NC_012785.1 1163756 1164472 R hypothetical protein complement(1163756..1164472) Kosmotoga olearia TBF 19.5.1 7968043 YP_002940803.1 CDS Kole_1097 NC_012785.1 1164551 1164871 D hypothetical protein 1164551..1164871 Kosmotoga olearia TBF 19.5.1 7968044 YP_002940804.1 CDS Kole_1098 NC_012785.1 1164908 1165663 D KEGG: baa:BA_1280 hypothetical protein; hypothetical protein 1164908..1165663 Kosmotoga olearia TBF 19.5.1 7968045 YP_002940805.1 CDS Kole_1099 NC_012785.1 1166055 1167392 D hypothetical protein 1166055..1167392 Kosmotoga olearia TBF 19.5.1 7968046 YP_002940806.1 CDS Kole_1100 NC_012785.1 1167405 1168871 D PFAM: peptidase C1A papain; cellulosome protein dockerin type I; SMART: peptidase C1A papain; KEGG: similar to cathepsin L preproprotein; peptidase C1A papain 1167405..1168871 Kosmotoga olearia TBF 19.5.1 7968047 YP_002940807.1 CDS Kole_1101 NC_012785.1 1168971 1170053 R PFAM: conserved hypothetical protein; KEGG: maq:Maqu_3008 hypothetical protein; hypothetical protein complement(1168971..1170053) Kosmotoga olearia TBF 19.5.1 7968048 YP_002940808.1 CDS Kole_1102 NC_012785.1 1170511 1171614 D PFAM: Extracellular ligand-binding receptor; KEGG: sfu:Sfum_0862 extracellular ligand-binding receptor; Extracellular ligand-binding receptor 1170511..1171614 Kosmotoga olearia TBF 19.5.1 7968049 YP_002940809.1 CDS Kole_1103 NC_012785.1 1171736 1172659 D PFAM: inner-membrane translocator; KEGG: dds:Ddes_1066 inner-membrane translocator; inner-membrane translocator 1171736..1172659 Kosmotoga olearia TBF 19.5.1 7968050 YP_002940810.1 CDS Kole_1104 NC_012785.1 1172659 1173726 D PFAM: inner-membrane translocator; KEGG: btr:Btr_1146 permease protein of ABC transporter; inner-membrane translocator 1172659..1173726 Kosmotoga olearia TBF 19.5.1 7968051 YP_002940811.1 CDS Kole_1105 NC_012785.1 1173719 1174558 D PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bqu:BQ06320 high-affinity branched-chain amino acid transport, ATP-binding protein; ABC transporter 1173719..1174558 Kosmotoga olearia TBF 19.5.1 7968052 YP_002940812.1 CDS Kole_1106 NC_012785.1 1174545 1175267 D PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: dds:Ddes_1069 ABC transporter related; ABC transporter 1174545..1175267 Kosmotoga olearia TBF 19.5.1 7968053 YP_002940813.1 CDS Kole_1107 NC_012785.1 1175296 1176117 D KEGG: sfu:Sfum_0197 pyrroline-5-carboxylate reductase; TIGRFAM: pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; pyrroline-5-carboxylate reductase 1175296..1176117 Kosmotoga olearia TBF 19.5.1 7968054 YP_002940814.1 CDS Kole_1108 NC_012785.1 1176583 1177716 D PFAM: glycosyl transferase family 2; KEGG: mms:mma_2647 haemin storage system, HmsR protein; glycosyl transferase family 2 1176583..1177716 Kosmotoga olearia TBF 19.5.1 7968055 YP_002940815.1 CDS Kole_1109 NC_012785.1 1177750 1178487 D PFAM: glycosyl transferase family 2; KEGG: hac:Hac_1461 glycosyl transferase; glycosyl transferase family 2 1177750..1178487 Kosmotoga olearia TBF 19.5.1 7968056 YP_002940816.1 CDS Kole_1110 NC_012785.1 1178484 1179545 D PFAM: conserved hypothetical protein; KEGG: ilo:IL0119 hypothetical protein; hypothetical protein 1178484..1179545 Kosmotoga olearia TBF 19.5.1 7968057 YP_002940817.1 CDS Kole_1111 NC_012785.1 1179629 1180252 D PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; KEGG: hypothetical protein; phospholipid/glycerol acyltransferase 1179629..1180252 Kosmotoga olearia TBF 19.5.1 7968058 YP_002940818.1 CDS Kole_1112 NC_012785.1 1180318 1180911 R KEGG: bha:BH2234 response regulatory protein (sensory transduction system); TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; diguanylate cyclase complement(1180318..1180911) Kosmotoga olearia TBF 19.5.1 7968059 YP_002940819.1 CDS Kole_1113 NC_012785.1 1181079 1182872 R PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; Peptidoglycan-binding LysM; SMART: Peptidoglycan-binding LysM; KEGG: sus:Acid_1294 2',3'-cyclic-nucleotide 2'-phosphodiesterase; 5'-Nucleotidase domain protein complement(1181079..1182872) Kosmotoga olearia TBF 19.5.1 7968060 YP_002940820.1 CDS Kole_1114 NC_012785.1 1183134 1183898 D KEGG: baa:BA_1104 hypothetical protein predicted by GeneMark; ABC transporter permease 1183134..1183898 Kosmotoga olearia TBF 19.5.1 7968061 YP_002940821.1 CDS Kole_1115 NC_012785.1 1183900 1184676 D PFAM: protein of unknown function DUF990; KEGG: reu:Reut_A1067 hypothetical protein; hypothetical protein 1183900..1184676 Kosmotoga olearia TBF 19.5.1 7967900 YP_002940822.1 CDS Kole_1116 NC_012785.1 1184700 1185668 D PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: baa:BA_1103 ABC transporter; ABC transporter 1184700..1185668 Kosmotoga olearia TBF 19.5.1 7967901 YP_002940823.1 CDS Kole_1117 NC_012785.1 1185725 1187422 R PFAM: carbon starvation protein CstA; KEGG: dat:HRM2_21730 CstA; carbon starvation protein CstA complement(1185725..1187422) Kosmotoga olearia TBF 19.5.1 7967902 YP_002940824.1 CDS Kole_1118 NC_012785.1 1187538 1188245 R PFAM: response regulator receiver; LytTr DNA-binding region; SMART: response regulator receiver; KEGG: baa:BA_0549 response regulator receiver domain; two component transcriptional regulator, LytTR family complement(1187538..1188245) Kosmotoga olearia TBF 19.5.1 7967903 YP_002940825.1 CDS Kole_1119 NC_012785.1 1188321 1190000 R PFAM: histidine kinase internal region; 5TM Receptors of the LytS-YhcK type transmembrane region; ATP-binding region ATPase domain protein; KEGG: baa:BA_0550 histidine kinase-like ATPases; signal transduction histidine kinase, LytS complement(1188321..1190000) Kosmotoga olearia TBF 19.5.1 7967904 YP_002940826.1 CDS Kole_1120 NC_012785.1 1190010 1190312 R hypothetical protein complement(1190010..1190312) Kosmotoga olearia TBF 19.5.1 7967905 YP_002940827.1 CDS Kole_1121 NC_012785.1 1190597 1191241 D PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: dde:Dde_2560 3-Cys thioredoxin peroxidase / 1-Cys peroxiredoxin; Peroxiredoxin 1190597..1191241 Kosmotoga olearia TBF 19.5.1 7967906 YP_002940828.1 CDS Kole_1122 NC_012785.1 1191290 1191673 R PFAM: transcriptional regulator PadR family protein; KEGG: baa:BA_1851 MarR family; PadR family transcriptional regulator complement(1191290..1191673) Kosmotoga olearia TBF 19.5.1 7967907 YP_002940829.1 CDS Kole_1123 NC_012785.1 1191760 1193106 R PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: dal:Dalk_0299 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD-dependent pyridine nucleotide-disulfide oxidoreductase complement(1191760..1193106) Kosmotoga olearia TBF 19.5.1 7967908 YP_002940830.1 CDS Kole_1124 NC_012785.1 1193112 1194071 R PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: sat:SYN_01173 radical SAM superfamily protein; Radical SAM domain protein complement(1193112..1194071) Kosmotoga olearia TBF 19.5.1 7967909 YP_002940831.1 CDS Kole_1125 NC_012785.1 1194068 1194355 R PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dat:HRM2_43830 ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein complement(1194068..1194355) Kosmotoga olearia TBF 19.5.1 7967910 YP_002940832.1 CDS Kole_1126 NC_012785.1 1194368 1194718 R PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein; KEGG: sat:SYN_01179 dinitrogenase iron-molybdenum cofactor protein; Dinitrogenase iron-molybdenum cofactor biosynthesis protein complement(1194368..1194718) Kosmotoga olearia TBF 19.5.1 7967911 YP_002940833.1 CDS Kole_1127 NC_012785.1 1194747 1195112 R PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein; KEGG: dat:HRM2_42470 hypothetical protein; Dinitrogenase iron-molybdenum cofactor biosynthesis protein complement(1194747..1195112) Kosmotoga olearia TBF 19.5.1 7967912 YP_002940834.1 CDS Kole_1128 NC_012785.1 1195124 1195987 R PFAM: Cobyrinic acid ac-diamide synthase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: pca:Pcar_0747 MinD family ATPase; Cobyrinic acid ac-diamide synthase complement(1195124..1195987) Kosmotoga olearia TBF 19.5.1 7967913 YP_002940835.1 CDS Kole_1129 NC_012785.1 1195984 1196832 R PFAM: Cobyrinic acid ac-diamide synthase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dol:Dole_0576 cobyrinic acid ac-diamide synthase; Cobyrinic acid ac-diamide synthase complement(1195984..1196832) Kosmotoga olearia TBF 19.5.1 7967914 YP_002940836.1 CDS Kole_1130 NC_012785.1 1196979 1197242 R KEGG: sat:SYN_01170 cytoplasmic protein; cytoplasmic protein complement(1196979..1197242) Kosmotoga olearia TBF 19.5.1 7967915 YP_002940837.1 CDS Kole_1131 NC_012785.1 1197247 1197534 R KEGG: hypothetical protein LOC100030415; hypothetical protein complement(1197247..1197534) Kosmotoga olearia TBF 19.5.1 7967916 YP_002940838.1 CDS Kole_1132 NC_012785.1 1198287 1198781 D PFAM: Inorganic pyrophosphatase; KEGG: bha:BH1604 inorganic pyrophosphatase; Inorganic diphosphatase 1198287..1198781 Kosmotoga olearia TBF 19.5.1 7967917 YP_002940839.1 CDS Kole_1133 NC_012785.1 1198793 1200502 R PFAM: metal-dependent phosphohydrolase HD sub domain; GAF domain protein; SMART: metal-dependent phosphohydrolase HD region; GAF domain protein; KEGG: mag:amb2500 HD-GYP domain-containing protein; metal dependent phosphohydrolase complement(1198793..1200502) Kosmotoga olearia TBF 19.5.1 7967918 YP_002940840.1 CDS Kole_1134 NC_012785.1 1200589 1201878 R KEGG: rfr:Rfer_3391 PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; PAS fold-3 domain protein; Metal-dependent hydrolase HDOD; SMART: metal-dependent phosphohydrolase HD region; PAC repeat-containing protein; PAS domain containing protein; PAS/PAC sensor protein complement(1200589..1201878) Kosmotoga olearia TBF 19.5.1 7967919 YP_002940841.1 CDS Kole_1135 NC_012785.1 1201908 1202033 D hypothetical protein 1201908..1202033 Kosmotoga olearia TBF 19.5.1 7967920 YP_002940842.1 CDS Kole_1136 NC_012785.1 1202082 1203266 D PFAM: Integrase catalytic region; KEGG: bja:bll1898 transposase; Integrase catalytic region 1202082..1203266 Kosmotoga olearia TBF 19.5.1 7967921 YP_002940843.1 CDS Kole_1137 NC_012785.1 1203329 1204402 D PFAM: transposase mutator type; KEGG: sun:SUN_2453 transposase; transposase mutator type 1203329..1204402 Kosmotoga olearia TBF 19.5.1 7967922 YP_002940844.1 CDS Kole_1138 NC_012785.1 1204399 1204563 R hypothetical protein complement(1204399..1204563) Kosmotoga olearia TBF 19.5.1 7967923 YP_002940845.1 CDS Kole_1139 NC_012785.1 1204748 1204939 D KEGG: sfu:Sfum_3308 conserved hypothetical cytosolic protein; conserved hypothetical cytosolic protein 1204748..1204939 Kosmotoga olearia TBF 19.5.1 7967924 YP_002940846.1 CDS Kole_1140 NC_012785.1 1205043 1205543 R KEGG: Fhad1; forkhead-associated (FHA) phosphopeptide binding domain 1; hypothetical protein complement(1205043..1205543) Kosmotoga olearia TBF 19.5.1 7967925 YP_002940847.1 CDS Kole_1141 NC_012785.1 1211247 1212461 R PFAM: transposase mutator type; KEGG: par:Psyc_0534 transposase mutator family protein; transposase mutator type complement(1211247..1212461) Kosmotoga olearia TBF 19.5.1 7967929 YP_002940848.1 CDS Kole_1142 NC_012785.1 1212805 1213800 R PFAM: peptidase M48 Ste24p; KEGG: dal:Dalk_2050 peptidase M48 Ste24p; peptidase M48 Ste24p complement(1212805..1213800) Kosmotoga olearia TBF 19.5.1 7967930 YP_002940849.1 CDS Kole_1143 NC_012785.1 1213803 1214366 R PFAM: LemA family protein; KEGG: aeh:Mlg_1468 LemA family protein; LemA family protein complement(1213803..1214366) Kosmotoga olearia TBF 19.5.1 7967931 YP_002940850.1 CDS Kole_1144 NC_012785.1 1214487 1215254 D TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: bar:GBAA5192 phosphatase; HAD-superfamily hydrolase, subfamily IIA 1214487..1215254 Kosmotoga olearia TBF 19.5.1 7967932 YP_002940851.1 CDS Kole_1145 NC_012785.1 1215464 1215988 D KEGG: hypothetical protein; hypothetical protein 1215464..1215988 Kosmotoga olearia TBF 19.5.1 7967933 YP_002940852.1 CDS Kole_1146 NC_012785.1 1216019 1216504 R KEGG: GD12145 gene product from transcript GD12145-RA; hypothetical protein complement(1216019..1216504) Kosmotoga olearia TBF 19.5.1 7967934 YP_002940853.1 CDS Kole_1147 NC_012785.1 1216519 1217064 R KEGG: glo:Glov_0132 hypothetical protein; hypothetical protein complement(1216519..1217064) Kosmotoga olearia TBF 19.5.1 7967935 YP_002940854.1 CDS Kole_1148 NC_012785.1 1217061 1217579 R KEGG: glo:Glov_0131 hypothetical protein; hypothetical protein complement(1217061..1217579) Kosmotoga olearia TBF 19.5.1 7967936 YP_002940855.1 CDS Kole_1149 NC_012785.1 1217698 1218648 R PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pub:SAR11_0812 ATP-binding component of ABC transporter; ABC transporter complement(1217698..1218648) Kosmotoga olearia TBF 19.5.1 7967937 YP_002940856.1 CDS Kole_1150 NC_012785.1 1218661 1219428 R PFAM: ABC-2 type transporter; KEGG: GM12733 gene product from transcript GM12733-RA; ABC transporter complement(1218661..1219428) Kosmotoga olearia TBF 19.5.1 7967938 YP_002940857.1 CDS Kole_1152 NC_012785.1 1219934 1220158 D hypothetical protein 1219934..1220158 Kosmotoga olearia TBF 19.5.1 7967940 YP_002940858.1 CDS Kole_1153 NC_012785.1 1221357 1222025 D hypothetical protein 1221357..1222025 Kosmotoga olearia TBF 19.5.1 7967943 YP_002940859.1 CDS Kole_1154 NC_012785.1 1222082 1223752 R catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase complement(1222082..1223752) Kosmotoga olearia TBF 19.5.1 7967944 YP_002940860.1 CDS Kole_1155 NC_012785.1 1223778 1224992 R PFAM: Hemerythrin HHE cation binding domain protein; KEGG: sus:Acid_2924 hypothetical protein; Hemerythrin HHE cation binding domain protein complement(1223778..1224992) Kosmotoga olearia TBF 19.5.1 7967945 YP_002940861.1 CDS Kole_1156 NC_012785.1 1225087 1225761 D PFAM: cyclic nucleotide-binding; SMART: regulatory protein Crp; cyclic nucleotide-binding; KEGG: dal:Dalk_3564 Crp/Fnr family transcriptional regulator; Crp/Fnr family transcriptional regulator 1225087..1225761 Kosmotoga olearia TBF 19.5.1 7967946 YP_002940862.1 CDS Kole_1157 NC_012785.1 1225915 1226574 D PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: cyclic nucleotide-binding; regulatory protein Crp; KEGG: geo:Geob_1003 Crp/Fnr family transcriptional regulator; Crp/Fnr family transcriptional regulator 1225915..1226574 Kosmotoga olearia TBF 19.5.1 7967947 YP_002940863.1 CDS Kole_1158 NC_012785.1 1226641 1227117 D KEGG: glo:Glov_0131 hypothetical protein; hypothetical protein 1226641..1227117 Kosmotoga olearia TBF 19.5.1 7967948 YP_002940864.1 CDS Kole_1159 NC_012785.1 1227114 1227839 D PFAM: Fe-S cluster domain protein; KEGG: glo:Glov_0132 hypothetical protein; Fe-S cluster domain protein 1227114..1227839 Kosmotoga olearia TBF 19.5.1 7967949 YP_002940865.1 CDS Kole_1161 NC_012785.1 1228125 1230719 D PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: sus:Acid_7574 hypothetical protein; PHP domain protein 1228125..1230719 Kosmotoga olearia TBF 19.5.1 7967951 YP_002940866.1 CDS Kole_1162 NC_012785.1 1230754 1230858 R hypothetical protein complement(1230754..1230858) Kosmotoga olearia TBF 19.5.1 7967952 YP_002940867.1 CDS Kole_1163 NC_012785.1 1231085 1231879 D PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: gme:Gmet_0013 daunorubicin resistance ABC transporter ATP-binding subunit; ABC transporter 1231085..1231879 Kosmotoga olearia TBF 19.5.1 7967953 YP_002940868.1 CDS Kole_1164 NC_012785.1 1231876 1232706 D PFAM: ABC-2 type transporter; KEGG: dps:DP1542 hypothetical protein; ABC transporter 1231876..1232706 Kosmotoga olearia TBF 19.5.1 7967954 YP_002940869.1 CDS Kole_1165 NC_012785.1 1232770 1234584 D PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bsu:BSU05950 hypothetical protein; ABC transporter 1232770..1234584 Kosmotoga olearia TBF 19.5.1 7967955 YP_002940870.1 CDS Kole_1166 NC_012785.1 1234586 1235044 R hypothetical protein complement(1234586..1235044) Kosmotoga olearia TBF 19.5.1 7967956 YP_002940871.1 CDS Kole_1167 NC_012785.1 1235170 1235607 R KEGG: neu:NE1602 general secretion pathway protein G; hypothetical protein complement(1235170..1235607) Kosmotoga olearia TBF 19.5.1 7967957 YP_002940872.1 CDS Kole_1168 NC_012785.1 1235762 1235914 D hypothetical protein 1235762..1235914 Kosmotoga olearia TBF 19.5.1 7967958 YP_002940873.1 CDS Kole_1169 NC_012785.1 1236410 1238227 R PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S15; WD40 domain protein beta Propeller; BAAT/Acyl-CoA thioester hydrolase; KEGG: nmu:Nmul_A2303 peptidase S9, prolyl oligopeptidase active site region; peptidase S9 prolyl oligopeptidase active site domain protein complement(1236410..1238227) Kosmotoga olearia TBF 19.5.1 7967959 YP_002940874.1 CDS Kole_1170 NC_012785.1 1238655 1239644 D PFAM: regulatory protein LacI; SMART: regulatory protein LacI; KEGG: bsu:BSU10840 LacI family transcription regulator; LacI family transcriptional regulator 1238655..1239644 Kosmotoga olearia TBF 19.5.1 7967960 YP_002940875.1 CDS Kole_1171 NC_012785.1 1239688 1240929 D PFAM: extracellular solute-binding protein family 1; KEGG: bha:BH1244 hypothetical protein; extracellular solute-binding protein family 1 1239688..1240929 Kosmotoga olearia TBF 19.5.1 7967961 YP_002940876.1 CDS Kole_1172 NC_012785.1 1241003 1241905 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bha:BH1245 hypothetical protein; binding-protein-dependent transport systems inner membrane component 1241003..1241905 Kosmotoga olearia TBF 19.5.1 7967962 YP_002940877.1 CDS Kole_1173 NC_012785.1 1241910 1242740 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bha:BH1246 hypothetical protein; binding-protein-dependent transport systems inner membrane component 1241910..1242740 Kosmotoga olearia TBF 19.5.1 7967963 YP_002940878.1 CDS Kole_1174 NC_012785.1 1242769 1244373 D PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: cja:CJA_0732 oligo-1,6-glucosidase, , glu13A; alpha amylase catalytic region 1242769..1244373 Kosmotoga olearia TBF 19.5.1 7967964 YP_002940879.1 CDS Kole_1175 NC_012785.1 1244447 1245838 R PFAM: Hyaluronidase; KEGG: hypothetical protein LOC100145437; Hyaluronidase complement(1244447..1245838) Kosmotoga olearia TBF 19.5.1 7967965 YP_002940880.1 CDS Kole_1176 NC_012785.1 1245860 1246750 R PFAM: ROK family protein; KEGG: bha:BH1425 glucose kinase; ROK family protein complement(1245860..1246750) Kosmotoga olearia TBF 19.5.1 7967966 YP_002940881.1 CDS Kole_1177 NC_012785.1 1246747 1248246 R hypothetical protein complement(1246747..1248246) Kosmotoga olearia TBF 19.5.1 7967967 YP_002940882.1 CDS Kole_1178 NC_012785.1 1248271 1251252 R PFAM: protein of unknown function DUF187; KEGG: mxa:MXAN_2624 lipoprotein; hypothetical protein complement(1248271..1251252) Kosmotoga olearia TBF 19.5.1 7967968 YP_002940883.1 CDS Kole_1179 NC_012785.1 1251249 1252082 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: cvi:CV_0260 sugar ABC transporter permease; binding-protein-dependent transport systems inner membrane component complement(1251249..1252082) Kosmotoga olearia TBF 19.5.1 7967969 YP_002940884.1 CDS Kole_1180 NC_012785.1 1252079 1253305 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: cvi:CV_0261 sugar ABC transporter permease protein; binding-protein-dependent transport systems inner membrane component complement(1252079..1253305) Kosmotoga olearia TBF 19.5.1 7967970 YP_002940885.1 CDS Kole_1181 NC_012785.1 1253413 1254654 R PFAM: extracellular solute-binding protein family 1; KEGG: cvi:CV_2897 sugar ABC transporter periplasmic sugar-binding protein; extracellular solute-binding protein family 1 complement(1253413..1254654) Kosmotoga olearia TBF 19.5.1 7967971 YP_002940886.1 CDS Kole_1182 NC_012785.1 1254683 1255996 R PFAM: FAD dependent oxidoreductase; glucose-inhibited division protein A; HI0933 family protein; KEGG: tbd:Tbd_1475 hypothetical protein; FAD dependent oxidoreductase complement(1254683..1255996) Kosmotoga olearia TBF 19.5.1 7967972 YP_002940887.1 CDS Kole_1183 NC_012785.1 1255993 1256712 R PFAM: N-acetylmannosamine-6-phosphate epimerase; KEGG: ent:Ent638_3230 N-acetylmannosamine-6-phosphate 2-epimerase; N-acylglucosamine-6-phosphate 2-epimerase complement(1255993..1256712) Kosmotoga olearia TBF 19.5.1 7967973 YP_002940888.1 CDS Kole_1184 NC_012785.1 1256925 1257776 D PFAM: sugar isomerase (SIS); helix-turn-helix protein RpiR; KEGG: apa:APP7_0748 HTH-type transcriptional regulator; RpiR family transcriptional regulator 1256925..1257776 Kosmotoga olearia TBF 19.5.1 7967974 YP_002940889.1 CDS Kole_1185 NC_012785.1 1257797 1258717 D PFAM: sugar isomerase (SIS); KEGG: rlt:Rleg2_4761 sugar isomerase (SIS); sugar isomerase (SIS) 1257797..1258717 Kosmotoga olearia TBF 19.5.1 7967975 YP_002940890.1 CDS Kole_1186 NC_012785.1 1259366 1259890 D PFAM: GCN5-related N-acetyltransferase; KEGG: bha:BH2121 hypothetical protein; GCN5-related N-acetyltransferase 1259366..1259890 Kosmotoga olearia TBF 19.5.1 7967976 YP_002940891.1 CDS Kole_1187 NC_012785.1 1259914 1261086 D PFAM: major facilitator superfamily MFS_1; KEGG: ppd:Ppro_2349 major facilitator transporter; major facilitator superfamily MFS_1 1259914..1261086 Kosmotoga olearia TBF 19.5.1 7967977 YP_002940892.1 CDS Kole_1188 NC_012785.1 1261108 1262004 D hypothetical protein 1261108..1262004 Kosmotoga olearia TBF 19.5.1 7967978 YP_002940893.1 CDS Kole_1189 NC_012785.1 1262056 1262697 D TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sbp:Sbal223_3996 phosphoglycolate phosphatase; HAD-superfamily hydrolase, subfamily IA, variant 1 1262056..1262697 Kosmotoga olearia TBF 19.5.1 7967979 YP_002940894.1 CDS Kole_1190 NC_012785.1 1262698 1264701 D PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; KEGG: baa:BA_0747 Peptidase_S9, prolyl oligopeptidase family; peptidase S9 prolyl oligopeptidase active site domain protein 1262698..1264701 Kosmotoga olearia TBF 19.5.1 7967980 YP_002940895.1 CDS Kole_1191 NC_012785.1 1264826 1265443 D PFAM: NUDIX hydrolase; KEGG: baa:BA_3089 NUDIX, MutT-like domain; NUDIX hydrolase 1264826..1265443 Kosmotoga olearia TBF 19.5.1 7969151 YP_002940896.1 CDS Kole_1192 NC_012785.1 1265440 1265970 D PFAM: GCN5-related N-acetyltransferase; KEGG: mms:mma_1698 streptothricin acetyltransferase; GCN5-related N-acetyltransferase 1265440..1265970 Kosmotoga olearia TBF 19.5.1 7969152 YP_002940897.1 CDS Kole_1193 NC_012785.1 1266012 1266761 D PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: xac:XAC4054 sodium ABC transporter ATP-binding protein; ABC transporter 1266012..1266761 Kosmotoga olearia TBF 19.5.1 7969153 YP_002940898.1 CDS Kole_1195 NC_012785.1 1267943 1269739 D KEGG: aca:ACP_2665 hypothetical protein; hypothetical protein 1267943..1269739 Kosmotoga olearia TBF 19.5.1 7969155 YP_002940899.1 CDS Kole_1196 NC_012785.1 1270380 1271303 D TIGRFAM: cysteinyl-tRNA synthetase; PFAM: TM1410 hypothetical-related protein; KEGG: mgm:Mmc1_3272 cysteinyl-tRNA synthetase; cysteinyl-tRNA synthetase 1270380..1271303 Kosmotoga olearia TBF 19.5.1 7969156 YP_002940900.1 CDS Kole_1197 NC_012785.1 1271851 1272762 D PFAM: protein of unknown function DUF6 transmembrane; KEGG: sek:SSPA3912 hypothetical protein; hypothetical protein 1271851..1272762 Kosmotoga olearia TBF 19.5.1 7969157 YP_002940901.1 CDS Kole_1198 NC_012785.1 1272768 1273022 R hypothetical protein complement(1272768..1273022) Kosmotoga olearia TBF 19.5.1 7969158 YP_002940902.1 CDS Kole_1199 NC_012785.1 1273525 1274514 D PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; KEGG: slo:Shew_1870 LacI family transcription regulator; LacI family transcriptional regulator 1273525..1274514 Kosmotoga olearia TBF 19.5.1 7969159 YP_002940903.1 CDS Kole_1200 NC_012785.1 1274515 1276362 D PFAM: Amylo-alpha-16-glucosidase; KEGG: bha:BH3691 hypothetical protein; Amylo-alpha-16-glucosidase 1274515..1276362 Kosmotoga olearia TBF 19.5.1 7969160 YP_002940904.1 CDS Kole_1201 NC_012785.1 1276359 1277570 D PFAM: extracellular solute-binding protein family 1; KEGG: bha:BH3690 sugar transport system (sugar-binding protein); extracellular solute-binding protein family 1 1276359..1277570 Kosmotoga olearia TBF 19.5.1 7969161 YP_002940905.1 CDS Kole_1202 NC_012785.1 1277616 1278782 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bha:BH3689 sugar transport system (permease); binding-protein-dependent transport systems inner membrane component 1277616..1278782 Kosmotoga olearia TBF 19.5.1 7969162 YP_002940906.1 CDS Kole_1203 NC_012785.1 1278802 1279689 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bha:BH3688 sugar transport system (permease); binding-protein-dependent transport systems inner membrane component 1278802..1279689 Kosmotoga olearia TBF 19.5.1 7969163 YP_002940907.1 CDS Kole_1204 NC_012785.1 1279694 1281292 D KEGG: hypothetical protein; Glycogen debranching protein-like protein 1279694..1281292 Kosmotoga olearia TBF 19.5.1 7969164 YP_002940908.1 CDS Kole_1205 NC_012785.1 1281984 1283156 R PFAM: protein of unknown function DUF401; Citrate transporter; KEGG: gsu:GSU1012 hypothetical protein; hypothetical protein complement(1281984..1283156) Kosmotoga olearia TBF 19.5.1 7969165 YP_002940909.1 CDS Kole_1206 NC_012785.1 1283973 1284944 D KEGG: gur:Gura_2929 metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; metal dependent phosphohydrolase 1283973..1284944 Kosmotoga olearia TBF 19.5.1 7969166 YP_002940910.1 CDS Kole_1207 NC_012785.1 1285006 1285356 D hypothetical protein 1285006..1285356 Kosmotoga olearia TBF 19.5.1 7969167 YP_002940911.1 CDS Kole_1208 NC_012785.1 1285669 1286190 R KEGG: dal:Dalk_4241 hypothetical protein; hypothetical protein complement(1285669..1286190) Kosmotoga olearia TBF 19.5.1 7969168 YP_002940912.1 CDS Kole_1210 NC_012785.1 1286820 1287866 R PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: bha:BH1089 hypothetical protein; Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase complement(1286820..1287866) Kosmotoga olearia TBF 19.5.1 7969170 YP_002940913.1 CDS Kole_1211 NC_012785.1 1287863 1288621 R KEGG: bsu:BSU09250 hypothetical protein; hypothetical protein complement(1287863..1288621) Kosmotoga olearia TBF 19.5.1 7969171 YP_002940914.1 CDS Kole_1212 NC_012785.1 1288696 1289991 R PFAM: major facilitator superfamily MFS_1; General substrate transporter; KEGG: MFS family transporter: sugar; major facilitator superfamily MFS_1 complement(1288696..1289991) Kosmotoga olearia TBF 19.5.1 7969172 YP_002940915.1 CDS Kole_1213 NC_012785.1 1290647 1290919 R KEGG: dol:Dole_0430 hypothetical protein; hypothetical protein complement(1290647..1290919) Kosmotoga olearia TBF 19.5.1 7969173 YP_002940916.1 CDS Kole_1214 NC_012785.1 1290921 1291133 R KEGG: tcx:Tcr_2112 hypothetical protein; hypothetical protein complement(1290921..1291133) Kosmotoga olearia TBF 19.5.1 7969174 YP_002940917.1 CDS Kole_1215 NC_012785.1 1291247 1291600 R KEGG: sat:SYN_00711 hypothetical protein; hypothetical protein complement(1291247..1291600) Kosmotoga olearia TBF 19.5.1 7969175 YP_002940918.1 CDS Kole_1217 NC_012785.1 1291994 1292203 D hypothetical protein 1291994..1292203 Kosmotoga olearia TBF 19.5.1 7969177 YP_002940919.1 CDS Kole_1218 NC_012785.1 1292981 1294330 R KEGG: dol:Dole_2515 glycosyl transferase group 1; glycosyl transferase group 1 complement(1292981..1294330) Kosmotoga olearia TBF 19.5.1 7969178 YP_002940920.1 CDS Kole_1219 NC_012785.1 1294357 1295448 R PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: baa:BA_4693 multiple sugar transport system ATP-binding protein; ABC transporter complement(1294357..1295448) Kosmotoga olearia TBF 19.5.1 7969179 YP_002940921.1 CDS Kole_1220 NC_012785.1 1295476 1296783 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ara:Arad_9760 sugar ABC transporter; binding-protein-dependent transport systems inner membrane component complement(1295476..1296783) Kosmotoga olearia TBF 19.5.1 7969180 YP_002940922.1 CDS Kole_1221 NC_012785.1 1296783 1297661 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ara:Arad_9761 sugar ABC transporter; binding-protein-dependent transport systems inner membrane component complement(1296783..1297661) Kosmotoga olearia TBF 19.5.1 7969181 YP_002940923.1 CDS Kole_1222 NC_012785.1 1297738 1298946 R PFAM: extracellular solute-binding protein family 1; KEGG: ara:Arad_9763 hypothetical protein; extracellular solute-binding protein family 1 complement(1297738..1298946) Kosmotoga olearia TBF 19.5.1 7969182 YP_002940924.1 CDS Kole_1223 NC_012785.1 1299197 1300198 D PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: bsu:BSU10840 LacI family transcription regulator; LacI family transcriptional regulator 1299197..1300198 Kosmotoga olearia TBF 19.5.1 7969183 YP_002940925.1 CDS Kole_1224 NC_012785.1 1300251 1300982 D hypothetical protein 1300251..1300982 Kosmotoga olearia TBF 19.5.1 7969184 YP_002940926.1 CDS Kole_1225 NC_012785.1 1301272 1301532 R hypothetical protein complement(1301272..1301532) Kosmotoga olearia TBF 19.5.1 7969185 YP_002940927.1 CDS Kole_1226 NC_012785.1 1301825 1302985 R PFAM: amidohydrolase; Amidohydrolase 3; KEGG: bha:BH3008 hypothetical protein; amidohydrolase complement(1301825..1302985) Kosmotoga olearia TBF 19.5.1 7969186 YP_002940928.1 CDS Kole_1227 NC_012785.1 1303493 1304695 R PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: sfu:Sfum_3896 isocitrate dehydrogenase, NADP-dependent; Isocitrate dehydrogenase (NADP(+)) complement(1303493..1304695) Kosmotoga olearia TBF 19.5.1 7969187 YP_002940929.1 CDS leuD NC_012785.1 1304702 1305205 R catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; 3-isopropylmalate dehydratase small subunit complement(1304702..1305205) Kosmotoga olearia TBF 19.5.1 7969188 YP_002940930.1 CDS Kole_1229 NC_012785.1 1305219 1306472 R catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; 3-isopropylmalate dehydratase large subunit complement(1305219..1306472) Kosmotoga olearia TBF 19.5.1 7969189 YP_002940931.1 CDS Kole_1230 NC_012785.1 1306476 1307615 R KEGG: bha:BH3160 methylcitrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase; 2-methylcitrate synthase/citrate synthase II complement(1306476..1307615) Kosmotoga olearia TBF 19.5.1 7969190 YP_002940932.1 CDS Kole_1231 NC_012785.1 1308739 1309776 D TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase zinc-binding; bifunctional deaminase-reductase domain protein; KEGG: ftn:FTN_0114 pyrimidine reductase/pyrimidine deaminase; riboflavin biosynthesis protein RibD 1308739..1309776 Kosmotoga olearia TBF 19.5.1 7969191 YP_002940933.1 CDS Kole_1232 NC_012785.1 1309761 1310318 D catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1309761..1310318 Kosmotoga olearia TBF 19.5.1 7969192 YP_002940934.1 CDS Kole_1233 NC_012785.1 1310323 1311495 D TIGRFAM: GTP cyclohydrolase II; PFAM: GTP cyclohydrolase II; 34-dihydroxy-2-butanone 4-phosphate synthase; KEGG: gme:Gmet_1626 GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone 4-phosphate synthase; GTP cyclohydrolase II 1310323..1311495 Kosmotoga olearia TBF 19.5.1 7969193 YP_002940935.1 CDS Kole_1234 NC_012785.1 1311492 1311962 D KEGG: baa:BA_4792 6,7-dimethyl-8-ribityllumazine synthase; TIGRFAM: 6,7-dimethyl-8-ribityllumazine synthase; PFAM: 67-dimethyl-8-ribityllumazine synthase; 6,7-dimethyl-8-ribityllumazine synthase 1311492..1311962 Kosmotoga olearia TBF 19.5.1 7969194 YP_002940936.1 CDS Kole_1235 NC_012785.1 1313268 1314497 D KEGG: gbm:Gbem_3173 metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; metal dependent phosphohydrolase 1313268..1314497 Kosmotoga olearia TBF 19.5.1 7969195 YP_002940937.1 CDS Kole_1236 NC_012785.1 1314725 1315855 D PFAM: major facilitator superfamily MFS_1; nucleoside:H symporter; KEGG: sfr:Sfri_2666 major facilitator superfamily MFS_1; major facilitator superfamily MFS_1 1314725..1315855 Kosmotoga olearia TBF 19.5.1 7969196 YP_002940938.1 CDS Kole_1237 NC_012785.1 1316515 1316892 D PFAM: transposase IS3/IS911 family protein; KEGG: net:Neut_1719 transposase IS3/IS911 family protein; transposase IS3/IS911 family protein 1316515..1316892 Kosmotoga olearia TBF 19.5.1 7969197 YP_002940939.1 CDS Kole_1238 NC_012785.1 1316919 1317821 D PFAM: Integrase catalytic region; KEGG: ypy:YPK_3925 integrase catalytic region; Integrase catalytic region 1316919..1317821 Kosmotoga olearia TBF 19.5.1 7969198 YP_002940940.1 CDS Kole_1239 NC_012785.1 1317905 1318042 R hypothetical protein complement(1317905..1318042) Kosmotoga olearia TBF 19.5.1 7969199 YP_002940941.1 CDS Kole_1240 NC_012785.1 1318129 1318563 D KEGG: neu:NE1602 general secretion pathway protein G; hypothetical protein 1318129..1318563 Kosmotoga olearia TBF 19.5.1 7969200 YP_002940942.1 CDS Kole_1241 NC_012785.1 1318770 1319432 R PFAM: GCN5-related N-acetyltransferase; KEGG: dal:Dalk_4126 GCN5-related N-acetyltransferase; GCN5-related N-acetyltransferase complement(1318770..1319432) Kosmotoga olearia TBF 19.5.1 7969201 YP_002940943.1 CDS Kole_1242 NC_012785.1 1319556 1319687 D PFAM: Desulfoferrodoxin Dfx domain protein; KEGG: sfu:Sfum_3891 desulfoferrodoxin; Desulfoferrodoxin Dfx domain protein 1319556..1319687 Kosmotoga olearia TBF 19.5.1 7969202 YP_002940944.1 CDS Kole_1243 NC_012785.1 1319798 1320301 D hypothetical protein 1319798..1320301 Kosmotoga olearia TBF 19.5.1 7969203 YP_002940945.1 CDS Kole_1244 NC_012785.1 1320659 1320772 D hypothetical protein 1320659..1320772 Kosmotoga olearia TBF 19.5.1 7969204 YP_002940946.1 CDS Kole_1245 NC_012785.1 1320929 1322200 D PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron maturase-specific domain protein; KEGG: amc:MADE_01366 hypothetical maturase; RNA-directed DNA polymerase (Reverse transcriptase) 1320929..1322200 Kosmotoga olearia TBF 19.5.1 7969205 YP_002940947.1 CDS Kole_1246 NC_012785.1 1322250 1323125 D TIGRFAM: sugar fermentation stimulation protein; PFAM: sugar fermentation stimulation protein; KEGG: bha:BH1042 sugar fermentation stimulation protein; sugar fermentation stimulation protein 1322250..1323125 Kosmotoga olearia TBF 19.5.1 7969206 YP_002940948.1 CDS Kole_1247 NC_012785.1 1323236 1323679 R PFAM: GCN5-related N-acetyltransferase; KEGG: scl:sce1382 hypothetical protein; GCN5-related N-acetyltransferase complement(1323236..1323679) Kosmotoga olearia TBF 19.5.1 7969207 YP_002940949.1 CDS Kole_1248 NC_012785.1 1323859 1324632 D PFAM: transglutaminase domain protein; SMART: transglutaminase domain protein; KEGG: spl:Spea_3677 hypothetical protein; transglutaminase domain protein 1323859..1324632 Kosmotoga olearia TBF 19.5.1 7969208 YP_002940950.1 CDS Kole_1249 NC_012785.1 1324683 1325159 D PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: bha:BH0948 bacterioferritin comigratory protein; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen 1324683..1325159 Kosmotoga olearia TBF 19.5.1 7969209 YP_002940951.1 CDS Kole_1250 NC_012785.1 1325846 1326928 D PFAM: basic membrane lipoprotein; KEGG: bov:BOV_A0007 Bmp family lipoprotein; basic membrane lipoprotein 1325846..1326928 Kosmotoga olearia TBF 19.5.1 7969210 YP_002940952.1 CDS Kole_1251 NC_012785.1 1327002 1328552 D PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: baa:BA_4398 simple sugar transport system ATP-binding protein; ABC transporter 1327002..1328552 Kosmotoga olearia TBF 19.5.1 7969211 YP_002940953.1 CDS Kole_1252 NC_012785.1 1328549 1329709 D PFAM: inner-membrane translocator; KEGG: bmt:BSUIS_B0010 hypothetical protein; inner-membrane translocator 1328549..1329709 Kosmotoga olearia TBF 19.5.1 7969212 YP_002940954.1 CDS Kole_1253 NC_012785.1 1329706 1330629 D PFAM: inner-membrane translocator; KEGG: bmt:BSUIS_B0009 hypothetical protein; inner-membrane translocator 1329706..1330629 Kosmotoga olearia TBF 19.5.1 7969213 YP_002940955.1 CDS Kole_1254 NC_012785.1 1330648 1331571 D PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: eum:ECUMN_0745 ribonucleoside hydrolase 1; Uridine nucleosidase 1330648..1331571 Kosmotoga olearia TBF 19.5.1 7969214 YP_002940956.1 CDS Kole_1255 NC_012785.1 1331617 1332378 D PFAM: purine or other phosphorylase family 1; KEGG: ses:SARI_03742 hypothetical protein; purine or other phosphorylase family 1 1331617..1332378 Kosmotoga olearia TBF 19.5.1 7969215 YP_002940957.1 CDS Kole_1256 NC_012785.1 1332918 1334198 D PFAM: Citrate transporter; Arsenical pump membrane protein; KEGG: baa:BA_0017 arsenical pump membrane protein; Citrate transporter 1332918..1334198 Kosmotoga olearia TBF 19.5.1 7969216 YP_002940958.1 CDS Kole_1257 NC_012785.1 1334678 1334965 R TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system; KEGG: xfn:XfasM23_1261 addiction module antitoxin; addiction module toxin, RelE/StbE family complement(1334678..1334965) Kosmotoga olearia TBF 19.5.1 7969217 YP_002940959.1 CDS Kole_1258 NC_012785.1 1334943 1335221 R hypothetical protein complement(1334943..1335221) Kosmotoga olearia TBF 19.5.1 7969218 YP_002940960.1 CDS Kole_1259 NC_012785.1 1335574 1336947 D KEGG: cbd:CBUD_1375 hypothetical ATPase; ATPase (AAA+ superfamily)-like protein 1335574..1336947 Kosmotoga olearia TBF 19.5.1 7969219 YP_002940961.1 CDS Kole_1260 NC_012785.1 1337170 1338207 R PFAM: metallophosphoesterase; KEGG: sus:Acid_3560 metallophosphoesterase; metallophosphoesterase complement(1337170..1338207) Kosmotoga olearia TBF 19.5.1 7969220 YP_002940962.1 CDS Kole_1261 NC_012785.1 1338442 1339716 R PFAM: UMUC domain protein DNA-repair protein; KEGG: sus:Acid_0850 DNA-directed DNA polymerase; DNA-directed DNA polymerase complement(1338442..1339716) Kosmotoga olearia TBF 19.5.1 7969221 YP_002940963.1 CDS Kole_1262 NC_012785.1 1340454 1341377 D PFAM: aminoglycoside phosphotransferase; KEGG: scl:sce5395 aminoglycoside phosphotransferase; aminoglycoside phosphotransferase 1340454..1341377 Kosmotoga olearia TBF 19.5.1 7969222 YP_002940964.1 CDS Kole_1263 NC_012785.1 1341348 1341656 R hypothetical protein complement(1341348..1341656) Kosmotoga olearia TBF 19.5.1 7969223 YP_002940965.1 CDS Kole_1264 NC_012785.1 1341656 1342348 R PFAM: protein of unknown function DUF1568; KEGG: aba:Acid345_2776 protein of unknown function DUF1568; hypothetical protein complement(1341656..1342348) Kosmotoga olearia TBF 19.5.1 7969224 YP_002940966.1 CDS Kole_1266 NC_012785.1 1342761 1343654 R PFAM: protein of unknown function DUF324; hypothetical protein complement(1342761..1343654) Kosmotoga olearia TBF 19.5.1 7969226 YP_002940967.1 CDS Kole_1267 NC_012785.1 1343651 1344052 R hypothetical protein complement(1343651..1344052) Kosmotoga olearia TBF 19.5.1 7969227 YP_002940968.1 CDS Kole_1268 NC_012785.1 1344045 1345025 R TIGRFAM: CRISPR-associated RAMP protein, Cmr4 family; PFAM: protein of unknown function DUF324; KEGG: sat:SYN_02249 hypothetical protein; CRISPR-associated RAMP protein, Cmr4 family complement(1344045..1345025) Kosmotoga olearia TBF 19.5.1 7969228 YP_002940969.1 CDS Kole_1269 NC_012785.1 1345012 1347732 R TIGRFAM: CRISPR-associated protein, Csx11 family; CRISPR-associated protein, Csx11 family complement(1345012..1347732) Kosmotoga olearia TBF 19.5.1 7969229 YP_002940970.1 CDS Kole_1270 NC_012785.1 1347729 1348802 R PFAM: protein of unknown function DUF324; hypothetical protein complement(1347729..1348802) Kosmotoga olearia TBF 19.5.1 7969230 YP_002940971.1 CDS Kole_1272 NC_012785.1 1350415 1351503 D KEGG: dal:Dalk_4194 transposase IS4 family protein; hypothetical protein 1350415..1351503 Kosmotoga olearia TBF 19.5.1 7967252 YP_002940972.1 CDS Kole_1273 NC_012785.1 1351816 1352757 R PFAM: metallophosphoesterase; KEGG: spl:Spea_3025 metallophosphoesterase; metallophosphoesterase complement(1351816..1352757) Kosmotoga olearia TBF 19.5.1 7967253 YP_002940973.1 CDS Kole_1274 NC_012785.1 1353154 1354734 D KEGG: aca:ACP_3267 hypothetical protein; hypothetical protein 1353154..1354734 Kosmotoga olearia TBF 19.5.1 7967254 YP_002940974.1 CDS Kole_1275 NC_012785.1 1355255 1355947 R PFAM: protein of unknown function DUF1568; KEGG: aba:Acid345_2776 protein of unknown function DUF1568; hypothetical protein complement(1355255..1355947) Kosmotoga olearia TBF 19.5.1 7967255 YP_002940975.1 CDS Kole_1276 NC_012785.1 1356070 1357065 R PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: sat:SYN_00015 transcriptional regulator; XRE family transcriptional regulator complement(1356070..1357065) Kosmotoga olearia TBF 19.5.1 7967256 YP_002940976.1 CDS Kole_1277 NC_012785.1 1357065 1357505 R hypothetical protein complement(1357065..1357505) Kosmotoga olearia TBF 19.5.1 7967257 YP_002940977.1 CDS Kole_1278 NC_012785.1 1357889 1359271 D KEGG: bha:BH3998 transposase (25); transposase (25) 1357889..1359271 Kosmotoga olearia TBF 19.5.1 7967258 YP_002940978.1 CDS Kole_1279 NC_012785.1 1359268 1359990 D PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: bha:BH3999 transposase (26); IstB domain protein ATP-binding protein 1359268..1359990 Kosmotoga olearia TBF 19.5.1 7967259 YP_002940979.1 CDS Kole_1280 NC_012785.1 1360039 1360158 R KEGG: wsu:WS2189 UDP-N-acetylglucosamine 2-epimerase WbpI; UDP-N-acetylglucosamine 2-epimerase WbpI complement(1360039..1360158) Kosmotoga olearia TBF 19.5.1 7967260 YP_002940980.1 CDS Kole_1281 NC_012785.1 1360478 1361545 R PFAM: N-acetylneuraminic acid synthase domain; SAF domain protein; KEGG: hch:HCH_05266 sialic acid synthase; N-acylneuraminate-9-phosphate synthase complement(1360478..1361545) Kosmotoga olearia TBF 19.5.1 7967261 YP_002940981.1 CDS Kole_1282 NC_012785.1 1361517 1363193 R PFAM: acylneuraminate cytidylyltransferase; KEGG: hch:HCH_05265 CMP-N-acetylneuraminic acid synthetase; N-acylneuraminate cytidylyltransferase complement(1361517..1363193) Kosmotoga olearia TBF 19.5.1 7967262 YP_002940982.1 CDS Kole_1284 NC_012785.1 1365000 1366457 R PFAM: polysaccharide biosynthesis protein; KEGG: vsp:VS_0223 capsular polysaccharide repeating unit transporter CpsL; polysaccharide biosynthesis protein complement(1365000..1366457) Kosmotoga olearia TBF 19.5.1 7967264 YP_002940983.1 CDS Kole_1285 NC_012785.1 1366775 1368484 R KEGG: abu:Abu_0045 asparagine synthetase (glutamine-hydrolyzing); hypothetical protein complement(1366775..1368484) Kosmotoga olearia TBF 19.5.1 7967265 YP_002940984.1 CDS Kole_1286 NC_012785.1 1369490 1370935 R KEGG: hch:HCH_05270 hypothetical protein; hypothetical protein complement(1369490..1370935) Kosmotoga olearia TBF 19.5.1 7967266 YP_002940985.1 CDS Kole_1287 NC_012785.1 1370892 1372160 R hypothetical protein complement(1370892..1372160) Kosmotoga olearia TBF 19.5.1 7967267 YP_002940986.1 CDS Kole_1288 NC_012785.1 1372199 1373284 R KEGG: dol:Dole_1825 glycosyl transferase group 1; hypothetical protein complement(1372199..1373284) Kosmotoga olearia TBF 19.5.1 7967268 YP_002940987.1 CDS Kole_1289 NC_012785.1 1373722 1374810 R PFAM: glycosyl transferase group 1; KEGG: dps:DPPB77 related to glycosyltransferase; glycosyl transferase group 1 complement(1373722..1374810) Kosmotoga olearia TBF 19.5.1 7967269 YP_002940988.1 CDS Kole_1290 NC_012785.1 1375168 1376454 R TIGRFAM: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: sugar transferase; KEGG: sde:Sde_0131 undecaprenyl-phosphate galactosephosphotransferase; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase complement(1375168..1376454) Kosmotoga olearia TBF 19.5.1 7967270 YP_002940989.1 CDS Kole_1291 NC_012785.1 1377339 1377605 D KEGG: sus:Acid_7477 hypothetical protein; hypothetical protein 1377339..1377605 Kosmotoga olearia TBF 19.5.1 7967271 YP_002940990.1 CDS Kole_1292 NC_012785.1 1377608 1377871 D hypothetical protein 1377608..1377871 Kosmotoga olearia TBF 19.5.1 7967272 YP_002940991.1 CDS Kole_1293 NC_012785.1 1378095 1379570 D KEGG: bha:BH3998 transposase (25); transposase (25) 1378095..1379570 Kosmotoga olearia TBF 19.5.1 7967273 YP_002940992.1 CDS Kole_1294 NC_012785.1 1379567 1380289 D PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: bha:BH3999 transposase (26); IstB domain protein ATP-binding protein 1379567..1380289 Kosmotoga olearia TBF 19.5.1 7967274 YP_002940993.1 CDS Kole_1295 NC_012785.1 1380343 1380747 D KEGG: azc:AZC_0130 PilT protein; PilT protein 1380343..1380747 Kosmotoga olearia TBF 19.5.1 7967275 YP_002940994.1 CDS Kole_1296 NC_012785.1 1381143 1381499 R PFAM: S23 ribosomal protein; KEGG: tbd:Tbd_0653 hypothetical protein; S23 ribosomal protein complement(1381143..1381499) Kosmotoga olearia TBF 19.5.1 7967276 YP_002940995.1 CDS Kole_1297 NC_012785.1 1382144 1383112 R PFAM: Domain of unknown function DUF1814; KEGG: sat:SYN_01915 cytoplasmic protein; hypothetical protein complement(1382144..1383112) Kosmotoga olearia TBF 19.5.1 7967277 YP_002940996.1 CDS Kole_1298 NC_012785.1 1383116 1383916 R KEGG: sat:SYN_01914 transcriptional regulator; transcriptional regulator complement(1383116..1383916) Kosmotoga olearia TBF 19.5.1 7967278 YP_002940997.1 CDS Kole_1299 NC_012785.1 1384039 1384449 R hypothetical protein complement(1384039..1384449) Kosmotoga olearia TBF 19.5.1 7967279 YP_002940998.1 CDS Kole_1300 NC_012785.1 1384434 1385795 R PFAM: ATPase; DUF234 DEXX-box ATPase; KEGG: sat:SYN_01513 ATPase; ATPase complement(1384434..1385795) Kosmotoga olearia TBF 19.5.1 7967280 YP_002940999.1 CDS Kole_1301 NC_012785.1 1386334 1387431 D PFAM: ATPase; KEGG: mmw:Mmwyl1_2441 hypothetical protein; ATPase 1386334..1387431 Kosmotoga olearia TBF 19.5.1 7967281 YP_002941000.1 CDS Kole_1302 NC_012785.1 1387891 1388340 R KEGG: ilo:IL0650 acetyltransferase; acetyltransferase complement(1387891..1388340) Kosmotoga olearia TBF 19.5.1 7967282 YP_002941001.1 CDS Kole_1303 NC_012785.1 1388393 1388995 R PFAM: transposase IS4 family protein; KEGG: dol:Dole_3091 transposase IS4 family protein; transposase IS4 family protein complement(1388393..1388995) Kosmotoga olearia TBF 19.5.1 7967283 YP_002941002.1 CDS Kole_1304 NC_012785.1 1388979 1389359 R hypothetical protein complement(1388979..1389359) Kosmotoga olearia TBF 19.5.1 7967284 YP_002941003.1 CDS Kole_1305 NC_012785.1 1389536 1389703 R hypothetical protein complement(1389536..1389703) Kosmotoga olearia TBF 19.5.1 7967285 YP_002941004.1 CDS Kole_1306 NC_012785.1 1390292 1390852 R transcriptional modulator of MazE/toxin, MazF complement(1390292..1390852) Kosmotoga olearia TBF 19.5.1 7967286 YP_002941005.1 CDS Kole_1307 NC_012785.1 1390932 1392050 R KEGG: rpi:Rpic_3170 plasmid maintenance system antidote protein, XRE family; TIGRFAM: addiction module antidote protein, HigA family; PFAM: helix-turn-helix domain protein; protein of unknown function DUF955; SMART: helix-turn-helix domain protein; XRE family transcriptional regulator complement(1390932..1392050) Kosmotoga olearia TBF 19.5.1 7967287 YP_002941006.1 CDS Kole_1308 NC_012785.1 1392062 1392373 R PFAM: plasmid maintenance system killer; plasmid maintenance system killer complement(1392062..1392373) Kosmotoga olearia TBF 19.5.1 7967288 YP_002941007.1 CDS Kole_1309 NC_012785.1 1393129 1393311 D hypothetical protein 1393129..1393311 Kosmotoga olearia TBF 19.5.1 7967289 YP_002941008.1 CDS Kole_1310 NC_012785.1 1393343 1393456 D hypothetical protein 1393343..1393456 Kosmotoga olearia TBF 19.5.1 7967290 YP_002941009.1 CDS Kole_1311 NC_012785.1 1393610 1394881 D PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron maturase-specific domain protein; KEGG: ppr:PBPRB0807 maturase; RNA-directed DNA polymerase (Reverse transcriptase) 1393610..1394881 Kosmotoga olearia TBF 19.5.1 7967291 YP_002941010.1 CDS Kole_1312 NC_012785.1 1395415 1395690 D TIGRFAM: prevent-host-death family protein; KEGG: geo:Geob_2073 prevent-host-death family protein; prevent-host-death family protein 1395415..1395690 Kosmotoga olearia TBF 19.5.1 7967292 YP_002941011.1 CDS Kole_1313 NC_012785.1 1395687 1396073 D PFAM: PilT protein domain protein; KEGG: dol:Dole_0924 nucleic acid binding protein; PilT protein domain protein 1395687..1396073 Kosmotoga olearia TBF 19.5.1 7967293 YP_002941012.1 CDS Kole_1314 NC_012785.1 1396478 1397446 R PFAM: Domain of unknown function DUF1814; KEGG: sat:SYN_01915 cytoplasmic protein; hypothetical protein complement(1396478..1397446) Kosmotoga olearia TBF 19.5.1 7967294 YP_002941013.1 CDS Kole_1315 NC_012785.1 1397450 1398250 R KEGG: sat:SYN_01914 transcriptional regulator; transcriptional regulator complement(1397450..1398250) Kosmotoga olearia TBF 19.5.1 7967295 YP_002941014.1 CDS Kole_1316 NC_012785.1 1398321 1398452 D hypothetical protein 1398321..1398452 Kosmotoga olearia TBF 19.5.1 7967296 YP_002941015.1 CDS Kole_1317 NC_012785.1 1398810 1400174 D PFAM: ATPase; DUF234 DEXX-box ATPase; KEGG: gme:Gmet_2667 DUF234 DEXX-box ATPase; ATPase 1398810..1400174 Kosmotoga olearia TBF 19.5.1 7967297 YP_002941016.1 CDS Kole_1318 NC_012785.1 1400317 1400673 R PFAM: S23 ribosomal protein; KEGG: xca:xccb100_0546 hypothetical protein; S23 ribosomal protein complement(1400317..1400673) Kosmotoga olearia TBF 19.5.1 7967298 YP_002941017.1 CDS Kole_1319 NC_012785.1 1400822 1401325 R nucleic acid-binding protein contains PIN domain-like protein complement(1400822..1401325) Kosmotoga olearia TBF 19.5.1 7967299 YP_002941018.1 CDS Kole_1320 NC_012785.1 1401325 1402053 R PFAM: protein of unknown function DUF955; KEGG: bja:bll7220 hypothetical protein; hypothetical protein complement(1401325..1402053) Kosmotoga olearia TBF 19.5.1 7967300 YP_002941019.1 CDS Kole_1321 NC_012785.1 1402040 1402363 R PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: swi:Swit_4067 helix-turn-helix domain-containing protein; XRE family transcriptional regulator complement(1402040..1402363) Kosmotoga olearia TBF 19.5.1 7967301 YP_002941020.1 CDS Kole_1322 NC_012785.1 1402966 1403496 D hypothetical protein 1402966..1403496 Kosmotoga olearia TBF 19.5.1 7967302 YP_002941021.1 CDS Kole_1323 NC_012785.1 1404005 1404271 D KEGG: sus:Acid_7477 hypothetical protein; hypothetical protein 1404005..1404271 Kosmotoga olearia TBF 19.5.1 7967303 YP_002941022.1 CDS Kole_1324 NC_012785.1 1404274 1404537 D hypothetical protein 1404274..1404537 Kosmotoga olearia TBF 19.5.1 7967304 YP_002941023.1 CDS Kole_1325 NC_012785.1 1404544 1404999 D PFAM: PilT protein domain protein; KEGG: azc:AZC_0130 PilT protein; PilT protein domain protein 1404544..1404999 Kosmotoga olearia TBF 19.5.1 7967305 YP_002941024.1 CDS Kole_1326 NC_012785.1 1404949 1405632 R hypothetical protein complement(1404949..1405632) Kosmotoga olearia TBF 19.5.1 7967306 YP_002941025.1 CDS Kole_1327 NC_012785.1 1405752 1405865 D hypothetical protein 1405752..1405865 Kosmotoga olearia TBF 19.5.1 7967307 YP_002941026.1 CDS Kole_1328 NC_012785.1 1406023 1406250 D hypothetical protein 1406023..1406250 Kosmotoga olearia TBF 19.5.1 7967308 YP_002941027.1 CDS Kole_1329 NC_012785.1 1406296 1407342 D KEGG: dat:HRM2_49130 hypothetical protein; hypothetical protein 1406296..1407342 Kosmotoga olearia TBF 19.5.1 7967309 YP_002941028.1 CDS Kole_1330 NC_012785.1 1407335 1408882 D KEGG: Viral A-type inclusion protein repeat containing protein; hypothetical protein 1407335..1408882 Kosmotoga olearia TBF 19.5.1 7967310 YP_002941029.1 CDS Kole_1331 NC_012785.1 1408872 1409588 D hypothetical protein 1408872..1409588 Kosmotoga olearia TBF 19.5.1 7967311 YP_002941030.1 CDS Kole_1332 NC_012785.1 1409590 1413957 D KEGG: viral A-type inclusion protein; Chromosome segregation ATPase-like protein 1409590..1413957 Kosmotoga olearia TBF 19.5.1 7967312 YP_002941031.1 CDS Kole_1333 NC_012785.1 1413951 1414055 D hypothetical protein 1413951..1414055 Kosmotoga olearia TBF 19.5.1 7967313 YP_002941032.1 CDS Kole_1334 NC_012785.1 1414552 1414734 D hypothetical protein 1414552..1414734 Kosmotoga olearia TBF 19.5.1 7967314 YP_002941033.1 CDS Kole_1335 NC_012785.1 1414766 1414879 D hypothetical protein 1414766..1414879 Kosmotoga olearia TBF 19.5.1 7967315 YP_002941034.1 CDS Kole_1336 NC_012785.1 1415033 1416304 D PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron maturase-specific domain protein; KEGG: ppr:PBPRB0807 maturase; RNA-directed DNA polymerase (Reverse transcriptase) 1415033..1416304 Kosmotoga olearia TBF 19.5.1 7967316 YP_002941035.1 CDS Kole_1337 NC_012785.1 1416554 1417744 R PFAM: beta-lactamase domain protein; flavodoxin/nitric oxide synthase; KEGG: cha:CHAB381_0232 flavodoxin; beta-lactamase domain protein complement(1416554..1417744) Kosmotoga olearia TBF 19.5.1 7967317 YP_002941036.1 CDS Kole_1338 NC_012785.1 1417847 1418101 R KEGG: rpe:RPE_2061 hypothetical protein; hypothetical protein complement(1417847..1418101) Kosmotoga olearia TBF 19.5.1 7967318 YP_002941037.1 CDS Kole_1339 NC_012785.1 1418254 1418511 D hypothetical protein 1418254..1418511 Kosmotoga olearia TBF 19.5.1 7967319 YP_002941038.1 CDS Kole_1340 NC_012785.1 1418806 1421103 D KEGG: glo:Glov_2771 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; extracellular solute-binding protein family 3; metal-dependent phosphohydrolase HD sub domain; PAS fold domain protein; PAS fold-4 domain protein; SMART: GGDEF domain containing protein; PAC repeat-containing protein; extracellular solute-binding protein family 3; diguanylate cyclase and metal dependent phosphohydrolase 1418806..1421103 Kosmotoga olearia TBF 19.5.1 7967320 YP_002941039.1 CDS Kole_1341 NC_012785.1 1421131 1422057 D PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mxa:MXAN_1597 ABC transporter, ATP-binding protein; ABC transporter 1421131..1422057 Kosmotoga olearia TBF 19.5.1 7967321 YP_002941040.1 CDS Kole_1342 NC_012785.1 1422060 1423223 D PFAM: ABC-2 type transporter; KEGG: dal:Dalk_2048 ABC-2 type transporter; ABC transporter 1422060..1423223 Kosmotoga olearia TBF 19.5.1 7967322 YP_002941041.1 CDS Kole_1343 NC_012785.1 1423216 1424280 D PFAM: ABC-2 type transporter; KEGG: dal:Dalk_2048 ABC-2 type transporter; ABC transporter 1423216..1424280 Kosmotoga olearia TBF 19.5.1 7967323 YP_002941042.1 CDS Kole_1344 NC_012785.1 1424652 1425551 R TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: mrd:Mrad2831_3363 cysteine synthase A; cysteine synthase complement(1424652..1425551) Kosmotoga olearia TBF 19.5.1 7967324 YP_002941043.1 CDS Kole_1345 NC_012785.1 1425538 1426113 R TIGRFAM: serine O-acetyltransferase; KEGG: pca:Pcar_1862 serine O-acetyltransferase; serine O-acetyltransferase complement(1425538..1426113) Kosmotoga olearia TBF 19.5.1 7967325 YP_002941044.1 CDS Kole_1346 NC_012785.1 1426853 1427008 R hypothetical protein complement(1426853..1427008) Kosmotoga olearia TBF 19.5.1 7967326 YP_002941045.1 CDS Kole_1347 NC_012785.1 1427365 1428354 R PFAM: protein of unknown function UPF0118; KEGG: rty:RT0621 permease; hypothetical protein complement(1427365..1428354) Kosmotoga olearia TBF 19.5.1 7967327 YP_002941046.1 CDS Kole_1348 NC_012785.1 1428536 1429087 R PFAM: regulatory protein TetR; KEGG: ypb:YPTS_1293 TetR family transcriptional regulator; TetR family transcriptional regulator complement(1428536..1429087) Kosmotoga olearia TBF 19.5.1 7967328 YP_002941047.1 CDS Kole_1349 NC_012785.1 1429317 1429499 D hypothetical protein 1429317..1429499 Kosmotoga olearia TBF 19.5.1 7967329 YP_002941048.1 CDS Kole_1350 NC_012785.1 1429499 1429747 D hypothetical protein 1429499..1429747 Kosmotoga olearia TBF 19.5.1 7967330 YP_002941049.1 CDS Kole_1351 NC_012785.1 1429757 1433092 R hypothetical protein complement(1429757..1433092) Kosmotoga olearia TBF 19.5.1 7967331 YP_002941050.1 CDS Kole_1352 NC_012785.1 1433158 1435185 R hypothetical protein complement(1433158..1435185) Kosmotoga olearia TBF 19.5.1 7967332 YP_002941051.1 CDS Kole_1353 NC_012785.1 1435304 1436395 R hypothetical protein complement(1435304..1436395) Kosmotoga olearia TBF 19.5.1 7968665 YP_002941052.1 CDS Kole_1354 NC_012785.1 1436392 1437879 R PFAM: Peptidase M23; 3D domain protein; Peptidoglycan-binding LysM; SMART: Peptidoglycan-binding LysM; KEGG: hypothetical protein; Peptidase M23 complement(1436392..1437879) Kosmotoga olearia TBF 19.5.1 7968666 YP_002941053.1 CDS Kole_1355 NC_012785.1 1437881 1438369 R KEGG: bsu:BSU15250 hypothetical protein; hypothetical protein complement(1437881..1438369) Kosmotoga olearia TBF 19.5.1 7968667 YP_002941054.1 CDS Kole_1356 NC_012785.1 1438419 1438691 R PFAM: histone family protein DNA-binding protein; SMART: histone family protein DNA-binding protein; KEGG: swi:Swit_0045 histone family protein DNA-binding protein; histone family protein DNA-binding protein complement(1438419..1438691) Kosmotoga olearia TBF 19.5.1 7968668 YP_002941055.1 CDS Kole_1357 NC_012785.1 1439125 1440417 D PFAM: transposase IS116/IS110/IS902 family protein; transposase IS111A/IS1328/IS1533; KEGG: bvi:Bcep1808_0314 transposase IS116/IS110/IS902 family protein; transposase IS116/IS110/IS902 family protein 1439125..1440417 Kosmotoga olearia TBF 19.5.1 7968669 YP_002941056.1 CDS Kole_1358 NC_012785.1 1440899 1441726 R PFAM: protein of unknown function DUF6 transmembrane; KEGG: baa:BA_3922 hypothetical protein; hypothetical protein complement(1440899..1441726) Kosmotoga olearia TBF 19.5.1 7968670 YP_002941057.1 CDS Kole_1359 NC_012785.1 1442031 1443359 D PFAM: Alkaline phosphatase; SMART: Alkaline phosphatase; KEGG: bha:BH0874 alkaline phosphatase; Alkaline phosphatase 1442031..1443359 Kosmotoga olearia TBF 19.5.1 7968671 YP_002941058.1 CDS Kole_1360 NC_012785.1 1443503 1446157 D KEGG: spc:Sputcn32_1453 hypothetical protein; hypothetical protein 1443503..1446157 Kosmotoga olearia TBF 19.5.1 7968672 YP_002941059.1 CDS Kole_1361 NC_012785.1 1446177 1447289 D KEGG: bxe:Bxe_B0648 UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; UDP-N-acetylglucosamine 2-epimerase 1446177..1447289 Kosmotoga olearia TBF 19.5.1 7968673 YP_002941060.1 CDS Kole_1362 NC_012785.1 1447294 1449036 D PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: tcx:Tcr_2180 PAS/PAC sensor hybrid histidine kinase; histidine kinase 1447294..1449036 Kosmotoga olearia TBF 19.5.1 7968674 YP_002941061.1 CDS Kole_1363 NC_012785.1 1449069 1449209 D hypothetical protein 1449069..1449209 Kosmotoga olearia TBF 19.5.1 7968675 YP_002941062.1 CDS Kole_1364 NC_012785.1 1449886 1451286 D PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase ; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; KEGG: vpa:VP2488 phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I 1449886..1451286 Kosmotoga olearia TBF 19.5.1 7968676 YP_002941063.1 CDS Kole_1365 NC_012785.1 1451291 1452013 D PFAM: Nucleotidyl transferase; KEGG: dps:DP1737 UDP-N-acetylglucosamine pyrophosphorylase; Glucosamine-1-phosphate N-acetyltransferase 1451291..1452013 Kosmotoga olearia TBF 19.5.1 7968677 YP_002941064.1 CDS Kole_1366 NC_012785.1 1452089 1452499 R PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: cha:CHAB381_1620 biotin/lipoyl attachment; biotin/lipoyl attachment domain-containing protein complement(1452089..1452499) Kosmotoga olearia TBF 19.5.1 7968678 YP_002941065.1 CDS Kole_1367 NC_012785.1 1452493 1452855 R hypothetical protein complement(1452493..1452855) Kosmotoga olearia TBF 19.5.1 7968679 YP_002941066.1 CDS Kole_1368 NC_012785.1 1452869 1454422 R PFAM: carboxyl transferase; KEGG: dal:Dalk_3780 propionyl-CoA carboxylase; carboxyl transferase complement(1452869..1454422) Kosmotoga olearia TBF 19.5.1 7968680 YP_002941067.1 CDS Kole_1369 NC_012785.1 1454422 1454829 R TIGRFAM: methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: bha:BH1468 hypothetical protein; methylmalonyl-CoA epimerase complement(1454422..1454829) Kosmotoga olearia TBF 19.5.1 7968681 YP_002941068.1 CDS Kole_1370 NC_012785.1 1454826 1455695 R TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; KEGG: aca:ACP_1023 LAO/AO transport system ATPase; LAO/AO transport system ATPase complement(1454826..1455695) Kosmotoga olearia TBF 19.5.1 7968682 YP_002941069.1 CDS Kole_1371 NC_012785.1 1455692 1456087 R PFAM: cobalamin B12-binding domain protein; KEGG: aba:Acid345_1432 methylmalonyl-CoA mutase; cobalamin B12-binding domain protein complement(1455692..1456087) Kosmotoga olearia TBF 19.5.1 7968683 YP_002941070.1 CDS Kole_1372 NC_012785.1 1456116 1457798 R KEGG: gur:Gura_0654 methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; methylmalonyl-CoA mutase, large subunit complement(1456116..1457798) Kosmotoga olearia TBF 19.5.1 7968684 YP_002941071.1 CDS Kole_1373 NC_012785.1 1458205 1458582 D PFAM: transposase IS3/IS911 family protein; KEGG: net:Neut_1719 transposase IS3/IS911 family protein; transposase IS3/IS911 family protein 1458205..1458582 Kosmotoga olearia TBF 19.5.1 7968685 YP_002941072.1 CDS Kole_1375 NC_012785.1 1459301 1460515 D PFAM: transposase mutator type; KEGG: par:Psyc_0534 transposase mutator family protein; transposase mutator type 1459301..1460515 Kosmotoga olearia TBF 19.5.1 7968687 YP_002941073.1 CDS Kole_1376 NC_012785.1 1461473 1463245 D PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: glo:Glov_0470 radical SAM domain protein; Radical SAM domain protein 1461473..1463245 Kosmotoga olearia TBF 19.5.1 7968688 YP_002941074.1 CDS Kole_1377 NC_012785.1 1463223 1464560 R TIGRFAM: UDP-N-acetylmuramate/alanine ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: glo:Glov_0669 UDP-N-acetylmuramate/alanine ligase; UDP-N-acetylmuramate/alanine ligase complement(1463223..1464560) Kosmotoga olearia TBF 19.5.1 7968689 YP_002941075.1 CDS Kole_1378 NC_012785.1 1464564 1465637 R KEGG: bha:BH2565 N-acetylglucosaminyl transferase; TIGRFAM: UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; PFAM: Glycosyltransferase 28 domain; glycosyl transferase family 28; UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase complement(1464564..1465637) Kosmotoga olearia TBF 19.5.1 7968690 YP_002941076.1 CDS Kole_1379 NC_012785.1 1465630 1466727 R PFAM: cell cycle protein; KEGG: rpr:RP280 rod shape-determining protein RodA (RodA); cell cycle protein complement(1465630..1466727) Kosmotoga olearia TBF 19.5.1 7968691 YP_002941077.1 CDS Kole_1380 NC_012785.1 1466727 1468076 R TIGRFAM: UDP-N-acetylmuramoylalanine/D-glutamate ligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; KEGG: mfa:Mfla_2271 UDP-N-acetylmuramoylalanine--D-glutamate ligase; UDP-N-acetylmuramoylalanine/D-glutamate ligase complement(1466727..1468076) Kosmotoga olearia TBF 19.5.1 7968692 YP_002941078.1 CDS Kole_1381 NC_012785.1 1468076 1469011 R KEGG: baa:BA_4523 glycosyl transferase; TIGRFAM: phospho-N-acetylmuramoyl-pentapeptide-transferase; PFAM: glycosyl transferase family 4; phospho-N-acetylmuramoyl-pentapeptide- transferase complement(1468076..1469011) Kosmotoga olearia TBF 19.5.1 7968693 YP_002941079.1 CDS Kole_1382 NC_012785.1 1469001 1470341 R TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; KEGG: aba:Acid345_3633 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase complement(1469001..1470341) Kosmotoga olearia TBF 19.5.1 7968694 YP_002941080.1 CDS Kole_1383 NC_012785.1 1470338 1471831 R TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; KEGG: bsu:BSU15180 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; UDP-N-acetylmuramyl-tripeptide synthetase complement(1470338..1471831) Kosmotoga olearia TBF 19.5.1 7968695 YP_002941081.1 CDS Kole_1384 NC_012785.1 1471941 1472987 D TIGRFAM: heat-inducible transcription repressor HrcA; KEGG: bha:BH1344 heat-inducible transcription repressor; heat-inducible transcription repressor HrcA 1471941..1472987 Kosmotoga olearia TBF 19.5.1 7968696 YP_002941082.1 CDS Kole_1385 NC_012785.1 1473007 1473627 D PFAM: GrpE protein; KEGG: fph:Fphi_1402 co-chaperone GrpE; GrpE protein 1473007..1473627 Kosmotoga olearia TBF 19.5.1 7968697 YP_002941083.1 CDS Kole_1386 NC_012785.1 1473637 1474746 D KEGG: bha:BH1348 heat-shock protein (activation of DnaK); TIGRFAM: chaperone protein DnaJ; PFAM: chaperone DnaJ domain protein; DnaJ central domain protein; heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; chaperone protein DnaJ 1473637..1474746 Kosmotoga olearia TBF 19.5.1 7968698 YP_002941084.1 CDS Kole_1387 NC_012785.1 1474751 1475611 D PFAM: protein of unknown function DUF161; KEGG: bha:BH3604 hypothetical protein; hypothetical protein 1474751..1475611 Kosmotoga olearia TBF 19.5.1 7968699 YP_002941085.1 CDS Kole_1388 NC_012785.1 1475629 1476300 D PFAM: peptidase M22 glycoprotease; KEGG: sat:SYN_00914 M22 family non-proteolytic peptidase; peptidase M22 glycoprotease 1475629..1476300 Kosmotoga olearia TBF 19.5.1 7968700 YP_002941086.1 CDS Kole_1389 NC_012785.1 1476284 1476922 D PFAM: HhH-GPD family protein; SMART: HhH-GPD family protein; KEGG: tgr:Tgr7_2009 HhH-GPD family protein; HhH-GPD family protein 1476284..1476922 Kosmotoga olearia TBF 19.5.1 7968701 YP_002941087.1 CDS Kole_1390 NC_012785.1 1476913 1478265 R TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; FAD dependent oxidoreductase; KEGG: mxa:MXAN_4219 alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase; dihydrolipoamide dehydrogenase complement(1476913..1478265) Kosmotoga olearia TBF 19.5.1 7968702 YP_002941088.1 CDS Kole_1391 NC_012785.1 1478285 1479499 R PFAM: type I phosphodiesterase/nucleotide pyrophosphatase; KEGG: eba:ebA5735 hypothetical protein; type I phosphodiesterase/nucleotide pyrophosphatase complement(1478285..1479499) Kosmotoga olearia TBF 19.5.1 7968703 YP_002941089.1 CDS Kole_1392 NC_012785.1 1479527 1482298 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: vsp:VS_II0222 ABC transporter: transmembrane protein; Maltooligosaccharide uptake; binding-protein-dependent transport systems inner membrane component complement(1479527..1482298) Kosmotoga olearia TBF 19.5.1 7968704 YP_002941090.1 CDS Kole_1393 NC_012785.1 1482298 1484043 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: hch:HCH_00441 maltose transporter membrane protein; binding-protein-dependent transport systems inner membrane component complement(1482298..1484043) Kosmotoga olearia TBF 19.5.1 7968705 YP_002941091.1 CDS Kole_1394 NC_012785.1 1484134 1485324 R PFAM: extracellular solute-binding protein family 1; KEGG: hch:HCH_00440 maltose ABC transporter periplasmic protein; extracellular solute-binding protein family 1 complement(1484134..1485324) Kosmotoga olearia TBF 19.5.1 7968706 YP_002941092.1 CDS Kole_1395 NC_012785.1 1485516 1486913 R PFAM: carboxylase; pyruvate carboxyltransferase; KEGG: mmw:Mmwyl1_3925 pyruvate carboxylase subunit B; carboxylase complement(1485516..1486913) Kosmotoga olearia TBF 19.5.1 7968707 YP_002941093.1 CDS Kole_1396 NC_012785.1 1486965 1488869 D GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 1486965..1488869 Kosmotoga olearia TBF 19.5.1 7968708 YP_002941094.1 CDS Kole_1397 NC_012785.1 1488890 1489069 R hypothetical protein complement(1488890..1489069) Kosmotoga olearia TBF 19.5.1 7968709 YP_002941095.1 CDS Kole_1398 NC_012785.1 1489296 1490003 D TIGRFAM: conserved hypothetical protein; PFAM: protein of unknown function DUF165; KEGG: dde:Dde_1833 hypothetical protein; hypothetical protein 1489296..1490003 Kosmotoga olearia TBF 19.5.1 7968711 YP_002941096.1 CDS Kole_1399 NC_012785.1 1490018 1491487 R PFAM: Amidohydrolase 3; KEGG: bar:GBAA4894 hypothetical protein; Amidohydrolase 3 complement(1490018..1491487) Kosmotoga olearia TBF 19.5.1 7968712 YP_002941097.1 CDS Kole_1400 NC_012785.1 1491474 1492343 R PFAM: Indigoidine synthase A family protein; KEGG: mno:Mnod_1045 indigoidine synthase A family protein; Indigoidine synthase A family protein complement(1491474..1492343) Kosmotoga olearia TBF 19.5.1 7968713 YP_002941098.1 CDS Kole_1401 NC_012785.1 1492366 1493076 R PFAM: Rhomboid family protein; KEGG: dde:Dde_1446 rhomboid family protein; Rhomboid family protein complement(1492366..1493076) Kosmotoga olearia TBF 19.5.1 7968714 YP_002941099.1 CDS Kole_1402 NC_012785.1 1493463 1494716 D PFAM: Glu/Leu/Phe/Val dehydrogenase ; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: sus:Acid_0039 glutamate dehydrogenase (NADP); Glu/Leu/Phe/Val dehydrogenase 1493463..1494716 Kosmotoga olearia TBF 19.5.1 7968716 YP_002941100.1 CDS infB NC_012785.1 1495005 1497092 R Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 complement(1495005..1497092) Kosmotoga olearia TBF 19.5.1 7968717 YP_002941101.1 CDS Kole_1404 NC_012785.1 1497070 1497396 R PFAM: ribosomal protein L7Ae/L30e/S12e/Gadd45; KEGG: bsu:BSU16620 hypothetical protein; ribosomal protein L7Ae/L30e/S12e/Gadd45 complement(1497070..1497396) Kosmotoga olearia TBF 19.5.1 7968718 YP_002941102.1 CDS Kole_1405 NC_012785.1 1497439 1498077 R KEGG: sus:Acid_7033 Zn-dependent hydrolase of the beta-lactamase fold-like protein; Zn-dependent hydrolase of the beta-lactamase fold-like protein complement(1497439..1498077) Kosmotoga olearia TBF 19.5.1 7968719 YP_002941103.1 CDS Kole_1406 NC_012785.1 1498264 1498815 R TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase; KEGG: aha:AHA_2848 phosphodiesterase; phosphodiesterase, MJ0936 family complement(1498264..1498815) Kosmotoga olearia TBF 19.5.1 7968720 YP_002941104.1 CDS Kole_1407 NC_012785.1 1498791 1499444 R TIGRFAM: thiamine pyrophosphokinase; PFAM: Thiamin pyrophosphokinase catalytic region; KEGG: thiamine pyrophosphokinase ; K00949 thiamine pyrophosphokinase; thiamine pyrophosphokinase complement(1498791..1499444) Kosmotoga olearia TBF 19.5.1 7968721 YP_002941105.1 CDS Kole_1408 NC_012785.1 1499441 1500604 R PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor; KEGG: sat:SYN_00945 RNA polymerase sigma-54 factor; sigma-54 DNA-binding domain protein complement(1499441..1500604) Kosmotoga olearia TBF 19.5.1 7968722 YP_002941106.1 CDS Kole_1409 NC_012785.1 1500594 1502141 R TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: YjeF-family domain protein; protein of unknown function UPF0031; KEGG: ppd:Ppro_2259 carbohydrate kinase, YjeF related protein; carbohydrate kinase, YjeF related protein complement(1500594..1502141) Kosmotoga olearia TBF 19.5.1 7968723 YP_002941107.1 CDS Kole_1410 NC_012785.1 1502249 1502959 D hypothetical protein 1502249..1502959 Kosmotoga olearia TBF 19.5.1 7968724 YP_002941108.1 CDS Kole_1411 NC_012785.1 1503811 1505136 R PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase; KEGG: RNA-metabolising metallo-beta-lactamase family protein; beta-lactamase domain protein complement(1503811..1505136) Kosmotoga olearia TBF 19.5.1 7968728 YP_002941109.1 CDS Kole_1412 NC_012785.1 1505680 1507035 D KEGG: dal:Dalk_0153 Na+/glutamate symporter-like protein; Na+/glutamate symporter-like protein 1505680..1507035 Kosmotoga olearia TBF 19.5.1 7968729 YP_002941110.1 CDS Kole_1413 NC_012785.1 1507081 1508178 R PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A; KEGG: hypothetical protein; von Willebrand factor type A complement(1507081..1508178) Kosmotoga olearia TBF 19.5.1 7968730 YP_002941111.1 CDS Kole_1414 NC_012785.1 1508192 1508695 R hypothetical protein complement(1508192..1508695) Kosmotoga olearia TBF 19.5.1 7968731 YP_002941112.1 CDS Kole_1415 NC_012785.1 1509347 1509442 R hypothetical protein complement(1509347..1509442) Kosmotoga olearia TBF 19.5.1 7968732 YP_002941113.1 CDS Kole_1416 NC_012785.1 1509474 1509572 R hypothetical protein complement(1509474..1509572) Kosmotoga olearia TBF 19.5.1 7968733 YP_002941114.1 CDS Kole_1417 NC_012785.1 1509912 1510685 D PFAM: GCN5-related N-acetyltransferase; KEGG: NAT8; N-acetyltransferase 8 (GCN5-related, ); GCN5-related N-acetyltransferase 1509912..1510685 Kosmotoga olearia TBF 19.5.1 7968734 YP_002941115.1 CDS proA NC_012785.1 1511078 1512322 D Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 1511078..1512322 Kosmotoga olearia TBF 19.5.1 7968735 YP_002941116.1 CDS Kole_1419 NC_012785.1 1512325 1513404 D catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 1512325..1513404 Kosmotoga olearia TBF 19.5.1 7968736 YP_002941117.1 CDS Kole_1420 NC_012785.1 1513551 1514390 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bha:BH1078 glycerol-3-phosphate ABC transporter (permease); binding-protein-dependent transport systems inner membrane component complement(1513551..1514390) Kosmotoga olearia TBF 19.5.1 7968737 YP_002941118.1 CDS Kole_1421 NC_012785.1 1514401 1515267 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: reh:H16_A2329 ABC-type transporter, permease component: CUT1 family; binding-protein-dependent transport systems inner membrane component complement(1514401..1515267) Kosmotoga olearia TBF 19.5.1 7968738 YP_002941119.1 CDS Kole_1422 NC_012785.1 1515359 1516669 R PFAM: extracellular solute-binding protein family 1; KEGG: bar:GBAA0569 glycerol-3-phosphate ABC transporter, glycerol-3-phosphate-binding protein; extracellular solute-binding protein family 1 complement(1515359..1516669) Kosmotoga olearia TBF 19.5.1 7968739 YP_002941120.1 CDS Kole_1423 NC_012785.1 1517019 1518203 D PFAM: Integrase catalytic region; KEGG: bja:bll1898 transposase; Integrase catalytic region 1517019..1518203 Kosmotoga olearia TBF 19.5.1 7968740 YP_002941121.1 CDS Kole_1424 NC_012785.1 1518181 1518372 D hypothetical protein 1518181..1518372 Kosmotoga olearia TBF 19.5.1 7968741 YP_002941122.1 CDS Kole_1426 NC_012785.1 1519440 1520237 R PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: sfu:Sfum_2832 IstB domain protein ATP-binding protein; IstB domain protein ATP-binding protein complement(1519440..1520237) Kosmotoga olearia TBF 19.5.1 7968743 YP_002941123.1 CDS Kole_1427 NC_012785.1 1520234 1521337 R PFAM: Integrase catalytic region; Resolvase helix-turn-helix domain protein; KEGG: sfu:Sfum_2833 integrase, catalytic region; Integrase catalytic region complement(1520234..1521337) Kosmotoga olearia TBF 19.5.1 7968744 YP_002941124.1 CDS Kole_1428 NC_012785.1 1522599 1523909 R PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: psp:PSPPH_1194 heavy metal sensor histidine kinase; histidine kinase complement(1522599..1523909) Kosmotoga olearia TBF 19.5.1 7968745 YP_002941125.1 CDS Kole_1429 NC_012785.1 1523906 1524592 R PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: gsu:GSU0451 DNA-binding response regulator; two component transcriptional regulator, winged helix family complement(1523906..1524592) Kosmotoga olearia TBF 19.5.1 7969070 YP_002941126.1 CDS Kole_1430 NC_012785.1 1524599 1525258 R hypothetical protein complement(1524599..1525258) Kosmotoga olearia TBF 19.5.1 7969071 YP_002941127.1 CDS Kole_1431 NC_012785.1 1525330 1526241 R KEGG: mxa:MXAN_3691 hypothetical protein; hypothetical protein complement(1525330..1526241) Kosmotoga olearia TBF 19.5.1 7969072 YP_002941128.1 CDS Kole_1432 NC_012785.1 1527234 1528172 R this enzyme from Pyrococcus has carbamoyl phosphate synthetase activity even though the enzyme shows sequence and structural similarity to carbamate kinase; this enzyme using carbate and ATP to synthesize carbamoyl phosphate which may be a favorable reaction at the extreme temperatures these organisms live under; carbamate kinase-like carbamoyl phosphate synthetase complement(1527234..1528172) Kosmotoga olearia TBF 19.5.1 7969073 YP_002941129.1 CDS Kole_1433 NC_012785.1 1528188 1529129 R catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase complement(1528188..1529129) Kosmotoga olearia TBF 19.5.1 7969074 YP_002941130.1 CDS argS NC_012785.1 1529314 1530942 D catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 1529314..1530942 Kosmotoga olearia TBF 19.5.1 7969075 YP_002941131.1 CDS Kole_1435 NC_012785.1 1530952 1532274 D KEGG: bha:BH0687 RNA methyltransferase; TIGRFAM: RNA methyltransferase, TrmA family; PFAM: (Uracil-5)-methyltransferase; protein of unknown function Met10; RNA methyltransferase, TrmA family 1530952..1532274 Kosmotoga olearia TBF 19.5.1 7969076 YP_002941132.1 CDS Kole_1436 NC_012785.1 1532261 1533037 R PFAM: inositol monophosphatase; KEGG: similar to AGAP006570-PA ; K01092 myo-inositol-1(or 4)-monophosphatase; inositol monophosphatase complement(1532261..1533037) Kosmotoga olearia TBF 19.5.1 7969077 YP_002941133.1 CDS Kole_1437 NC_012785.1 1533207 1539494 D PFAM: Fibronectin type III domain protein; SMART: Fibronectin type III domain protein; KEGG: mmr:Mmar10_1504 cadherin; Fibronectin type III domain protein 1533207..1539494 Kosmotoga olearia TBF 19.5.1 7969078 YP_002941134.1 CDS Kole_1438 NC_012785.1 1539530 1540432 D PFAM: phosphate acetyl/butaryl transferase; KEGG: baa:BA_4843 PTA_PTB, phosphate acetyl/butaryl transferase; Phosphate butyryltransferase 1539530..1540432 Kosmotoga olearia TBF 19.5.1 7969079 YP_002941135.1 CDS Kole_1439 NC_012785.1 1540429 1540617 D PFAM: thiamineS protein; sulfur carrier protein ThiS 1540429..1540617 Kosmotoga olearia TBF 19.5.1 7969080 YP_002941136.1 CDS Kole_1440 NC_012785.1 1540890 1541732 D PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: mgm:Mmc1_1921 serine/threonine protein kinase; serine/threonine protein kinase 1540890..1541732 Kosmotoga olearia TBF 19.5.1 7969081 YP_002941137.1 CDS Kole_1441 NC_012785.1 1541734 1542591 R PFAM: Polyprenyl synthetase; KEGG: bhe:BH15260 geranyltranstransferase (farnesyl-diphosphate synthase); Polyprenyl synthetase complement(1541734..1542591) Kosmotoga olearia TBF 19.5.1 7969082 YP_002941138.1 CDS Kole_1442 NC_012785.1 1542563 1543096 R PFAM: protein of unknown function DUF151; KEGG: aca:ACP_0464 hypothetical protein; hypothetical protein complement(1542563..1543096) Kosmotoga olearia TBF 19.5.1 7969083 YP_002941139.1 CDS Kole_1443 NC_012785.1 1543113 1543898 R KEGG: baa:BA_2745 phosphate acyltransferases; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; 1-acyl-sn-glycerol-3-phosphate acyltransferase complement(1543113..1543898) Kosmotoga olearia TBF 19.5.1 7969084 YP_002941140.1 CDS Kole_1444 NC_012785.1 1543864 1545078 R TIGRFAM: thiamine biosynthesis/tRNA modification protein ThiI; PFAM: thiamine biosynthesis protein; THUMP domain protein; ExsB family protein; KEGG: cbg:CbuG_0830 thiamine biosynthesis protein; thiamine biosynthesis/tRNA modification protein ThiI complement(1543864..1545078) Kosmotoga olearia TBF 19.5.1 7969085 YP_002941141.1 CDS Kole_1445 NC_012785.1 1545149 1545871 D KEGG: dal:Dalk_2751 TPR repeat-containing protein; hypothetical protein 1545149..1545871 Kosmotoga olearia TBF 19.5.1 7969086 YP_002941142.1 CDS Kole_1446 NC_012785.1 1545873 1546340 D KEGG: MGC138914; hypothetical LOC512219; hypothetical protein 1545873..1546340 Kosmotoga olearia TBF 19.5.1 7969087 YP_002941143.1 CDS Kole_1447 NC_012785.1 1546337 1547506 D PFAM: Radical SAM domain protein; cobalamin B12-binding domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: mxa:MXAN_6449 B12 binding/radical SAM domain protein; Radical SAM domain protein 1546337..1547506 Kosmotoga olearia TBF 19.5.1 7969088 YP_002941144.1 CDS Kole_1448 NC_012785.1 1547514 1548320 D PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: cjd:JJD26997_0671 carbon-nitrogen hydrolase; Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase 1547514..1548320 Kosmotoga olearia TBF 19.5.1 7969089 YP_002941145.1 CDS Kole_1449 NC_012785.1 1548564 1549118 D TIGRFAM: translation initiation factor IF-3; PFAM: initiation factor 3; KEGG: sfu:Sfum_0425 translation initiation factor IF-3; translation initiation factor IF-3 1548564..1549118 Kosmotoga olearia TBF 19.5.1 7969091 YP_002941146.1 CDS Kole_1450 NC_012785.1 1549111 1549314 D TIGRFAM: ribosomal protein L35; PFAM: ribosomal protein L35; KEGG: Os06g0647100; hypothetical protein; ribosomal protein L35 1549111..1549314 Kosmotoga olearia TBF 19.5.1 7969092 YP_002941147.1 CDS rplT NC_012785.1 1549346 1549702 D binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 1549346..1549702 Kosmotoga olearia TBF 19.5.1 7969093 YP_002941148.1 CDS Kole_1452 NC_012785.1 1549795 1550211 D PFAM: OsmC family protein; KEGG: pnu:Pnuc_1887 OsmC family protein; OsmC family protein 1549795..1550211 Kosmotoga olearia TBF 19.5.1 7969094 YP_002941149.1 CDS Kole_1453 NC_012785.1 1550215 1551024 D PFAM: Cobyrinic acid ac-diamide synthase; KEGG: sat:SYN_01185 iron-sulfur cluster assembly/repair protein; Cobyrinic acid ac-diamide synthase 1550215..1551024 Kosmotoga olearia TBF 19.5.1 7969095 YP_002941150.1 CDS Kole_1454 NC_012785.1 1551026 1552069 D KEGG: aba:Acid345_1175 translation initiation factor 2B subunit I family (IF-2BI); TIGRFAM: translation initiation factor, aIF-2BI family; eIF-2B alpha/beta/delta-related uncharacterized protein; PFAM: initiation factor 2B related; translation initiation factor, aIF-2BI family 1551026..1552069 Kosmotoga olearia TBF 19.5.1 7969096 YP_002941151.1 CDS Kole_1455 NC_012785.1 1552136 1554217 D KEGG: baa:BA_3251 alpha amylase, catalytic domain; TIGRFAM: pullulanase, type I; PFAM: alpha amylase catalytic region; glycoside hydrolase family 13 domain protein; SMART: alpha amylase catalytic sub domain; pullulanase, type I 1552136..1554217 Kosmotoga olearia TBF 19.5.1 7969097 YP_002941152.1 CDS glyA NC_012785.1 1554554 1555822 D catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 1554554..1555822 Kosmotoga olearia TBF 19.5.1 7969098 YP_002941153.1 CDS Kole_1457 NC_012785.1 1555837 1556463 D TIGRFAM: uracil phosphoribosyltransferase; KEGG: baa:BA_0411 phosphoribosyl transferase domain; uracil phosphoribosyltransferase 1555837..1556463 Kosmotoga olearia TBF 19.5.1 7969099 YP_002941154.1 CDS Kole_1458 NC_012785.1 1556499 1560563 D PFAM: glycoside hydrolase family 57; glycoside hydrolase starch-binding; KEGG: gsu:GSU3255 hypothetical protein; glycoside hydrolase family 57 1556499..1560563 Kosmotoga olearia TBF 19.5.1 7969100 YP_002941155.1 CDS Kole_1459 NC_012785.1 1560655 1561221 D catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1560655..1561221 Kosmotoga olearia TBF 19.5.1 7969101 YP_002941156.1 CDS Kole_1460 NC_012785.1 1561420 1562736 D KEGG: bha:BH2484 signal recognition particle; TIGRFAM: signal recognition particle protein; PFAM: GTP-binding signal recognition particle SRP54 G- domain; Signal peptide binding (SRP54) M- domain protein; GTP-binding signal recognition particle SRP54 helical bundle; SMART: AAA ATPase; signal recognition particle protein 1561420..1562736 Kosmotoga olearia TBF 19.5.1 7969102 YP_002941157.1 CDS Kole_1461 NC_012785.1 1562767 1563060 D TIGRFAM: ribosomal protein S16; PFAM: ribosomal protein S16; KEGG: glo:Glov_2450 ribosomal protein S16; ribosomal protein S16 1562767..1563060 Kosmotoga olearia TBF 19.5.1 7969103 YP_002941158.1 CDS Kole_1462 NC_012785.1 1563060 1563293 D KEGG: gme:Gmet_2870 KH, type 1; KH, type 1 1563060..1563293 Kosmotoga olearia TBF 19.5.1 7969104 YP_002941159.1 CDS Kole_1463 NC_012785.1 1563290 1563892 D TIGRFAM: 16S rRNA processing protein RimM; PFAM: RimM protein; PRC-barrel domain protein; KEGG: pfl:PFL_1095 16S rRNA-processing protein; 16S rRNA processing protein RimM 1563290..1563892 Kosmotoga olearia TBF 19.5.1 7969105 YP_002941160.1 CDS Kole_1464 NC_012785.1 1563861 1564607 D KEGG: gur:Gura_3760 tRNA (guanine-N1)-methyltransferase; TIGRFAM: tRNA (guanine-N1)-methyltransferase; PFAM: tRNA (guanine-N1-)-methyltransferase; tRNA (guanine-N1)-methyltransferase 1563861..1564607 Kosmotoga olearia TBF 19.5.1 7969106 YP_002941161.1 CDS Kole_1465 NC_012785.1 1564597 1565163 D KEGG: gur:Gura_3759 hypothetical protein; hypothetical protein 1564597..1565163 Kosmotoga olearia TBF 19.5.1 7969107 YP_002941162.1 CDS Kole_1466 NC_012785.1 1565180 1565527 D TIGRFAM: ribosomal protein L19; PFAM: ribosomal protein L19; KEGG: bha:BH2478 50S ribosomal protein L19; ribosomal protein L19 1565180..1565527 Kosmotoga olearia TBF 19.5.1 7969108 YP_002941163.1 CDS Kole_1467 NC_012785.1 1565524 1566390 D TIGRFAM: signal peptidase I; PFAM: peptidase S24 and S26 domain protein; KEGG: bav:BAV1130 signal peptidase I; signal peptidase I 1565524..1566390 Kosmotoga olearia TBF 19.5.1 7969109 YP_002941164.1 CDS Kole_1468 NC_012785.1 1566573 1567346 D PFAM: protein of unknown function DUF198; KEGG: pca:Pcar_2981 GTP cyclohydrolase; hypothetical protein 1566573..1567346 Kosmotoga olearia TBF 19.5.1 7969111 YP_002941165.1 CDS Kole_1469 NC_012785.1 1567343 1568017 D TIGRFAM: methyltransferase GidB; PFAM: glucose inhibited division protein; KEGG: hypothetical protein; methyltransferase GidB 1567343..1568017 Kosmotoga olearia TBF 19.5.1 7969112 YP_002941166.1 CDS Kole_1470 NC_012785.1 1568007 1568711 D PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: geo:Geob_1497 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase; uroporphyrin-III C/tetrapyrrole methyltransferase 1568007..1568711 Kosmotoga olearia TBF 19.5.1 7969113 YP_002941167.1 CDS Kole_1471 NC_012785.1 1568713 1569348 D PFAM: peptidase M50; KEGG: dps:DP0062 hypothetical protein; peptidase M50 1568713..1569348 Kosmotoga olearia TBF 19.5.1 7969114 YP_002941168.1 CDS Kole_1472 NC_012785.1 1569357 1571822 R KEGG: gur:Gura_0070 APHP domain-containing protein; hypothetical protein complement(1569357..1571822) Kosmotoga olearia TBF 19.5.1 7969115 YP_002941169.1 CDS Kole_1473 NC_012785.1 1571791 1572771 R PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: nam:NAMH_1550 MgpA protein; phosphoesterase RecJ domain protein complement(1571791..1572771) Kosmotoga olearia TBF 19.5.1 7969116 YP_002941170.1 CDS Kole_1474 NC_012785.1 1572785 1573591 R TIGRFAM: purine nucleoside phosphorylase I, inosine and guanosine-specific; inosine guanosine and xanthosine phosphorylase family; PFAM: purine or other phosphorylase family 1; KEGG: baa:BA_4766 Mtap_PNP, phosphorylase family 2; purine nucleoside phosphorylase I, inosine and guanosine-specific complement(1572785..1573591) Kosmotoga olearia TBF 19.5.1 7969117 YP_002941171.1 CDS Kole_1475 NC_012785.1 1573778 1574035 D TIGRFAM: acyl carrier protein; PFAM: phosphopantetheine-binding; KEGG: afw:Anae109_2736 acyl carrier protein; acyl carrier protein 1573778..1574035 Kosmotoga olearia TBF 19.5.1 7969118 YP_002941172.1 CDS Kole_1476 NC_012785.1 1574096 1574995 D KEGG: mxa:MXAN_5912 pseudouridine synthase, RluA family; TIGRFAM: pseudouridine synthase, RluA family; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; pseudouridine synthase, RluA family 1574096..1574995 Kosmotoga olearia TBF 19.5.1 7969119 YP_002941173.1 CDS Kole_1477 NC_012785.1 1574992 1575759 D hypothetical protein 1574992..1575759 Kosmotoga olearia TBF 19.5.1 7969120 YP_002941174.1 CDS Kole_1478 NC_012785.1 1575756 1577219 D hypothetical protein 1575756..1577219 Kosmotoga olearia TBF 19.5.1 7969121 YP_002941175.1 CDS Kole_1479 NC_012785.1 1577233 1578834 D PFAM: PEGA domain protein; KEGG: aba:Acid345_0037 serine/threonine protein kinase; PEGA domain protein 1577233..1578834 Kosmotoga olearia TBF 19.5.1 7969122 YP_002941176.1 CDS Kole_1480 NC_012785.1 1578858 1579565 R PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; KEGG: msu:MS0391 RsuA protein; pseudouridine synthase complement(1578858..1579565) Kosmotoga olearia TBF 19.5.1 7969123 YP_002941177.1 CDS Kole_1481 NC_012785.1 1579684 1582827 D TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: bha:BH1240 single-strand DNA-specific exonuclease; single-stranded-DNA-specific exonuclease RecJ 1579684..1582827 Kosmotoga olearia TBF 19.5.1 7969124 YP_002941178.1 CDS Kole_1482 NC_012785.1 1582820 1583092 D hypothetical protein 1582820..1583092 Kosmotoga olearia TBF 19.5.1 7969125 YP_002941179.1 CDS Kole_1484 NC_012785.1 1583876 1584886 D TIGRFAM: cell shape determining protein, MreB/Mrl family; PFAM: cell shape determining protein MreB/Mrl; cell division protein FtsA; KEGG: pca:Pcar_1049 rod shape-determining protein MreB; cell shape determining protein, MreB/Mrl family 1583876..1584886 Kosmotoga olearia TBF 19.5.1 7969128 YP_002941180.1 CDS Kole_1485 NC_012785.1 1584889 1585713 R PFAM: protein of unknown function DUF368; KEGG: mmw:Mmwyl1_1306 hypothetical protein; hypothetical protein complement(1584889..1585713) Kosmotoga olearia TBF 19.5.1 7969129 YP_002941181.1 CDS Kole_1486 NC_012785.1 1586254 1586997 D KEGG: maq:Maqu_3152 FeS assembly ATPase SufC; TIGRFAM: FeS assembly ATPase SufC; PFAM: ABC transporter related; SMART: AAA ATPase; FeS assembly ATPase SufC 1586254..1586997 Kosmotoga olearia TBF 19.5.1 7969130 YP_002941182.1 CDS Kole_1487 NC_012785.1 1587008 1588402 D TIGRFAM: FeS assembly protein SufB; PFAM: SufBD protein; KEGG: baa:BA_0086 uncharacterized protein family (UPF0051); FeS assembly protein SufB 1587008..1588402 Kosmotoga olearia TBF 19.5.1 7969131 YP_002941183.1 CDS Kole_1488 NC_012785.1 1588415 1589617 D PFAM: SufBD protein; KEGG: xop:PXO_01977 FeS assembly protein SufD; SufBD protein 1588415..1589617 Kosmotoga olearia TBF 19.5.1 7969132 YP_002941184.1 CDS Kole_1489 NC_012785.1 1589592 1590815 D TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: aminotransferase class V; KEGG: bsu:BSU32690 cysteine desulfurase; cysteine desulfurase, SufS subfamily 1589592..1590815 Kosmotoga olearia TBF 19.5.1 7969133 YP_002941185.1 CDS Kole_1490 NC_012785.1 1590812 1591252 D TIGRFAM: SUF system FeS assembly protein, NifU family; PFAM: nitrogen-fixing NifU domain protein; KEGG: pub:SAR11_0743 NifU-like protein; SUF system FeS assembly protein, NifU family 1590812..1591252 Kosmotoga olearia TBF 19.5.1 7969134 YP_002941186.1 CDS Kole_1491 NC_012785.1 1591481 1591684 D PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: pca:Pcar_0201 cold shock protein; cold-shock DNA-binding domain protein 1591481..1591684 Kosmotoga olearia TBF 19.5.1 7969135 YP_002941187.1 CDS Kole_1492 NC_012785.1 1591758 1592948 R catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase complement(1591758..1592948) Kosmotoga olearia TBF 19.5.1 7969136 YP_002941188.1 CDS Kole_1493 NC_012785.1 1592982 1594442 R SMART: von Willebrand factor type A; KEGG: pin:Ping_3152 hypothetical protein; von Willebrand factor type A complement(1592982..1594442) Kosmotoga olearia TBF 19.5.1 7969137 YP_002941189.1 CDS Kole_1494 NC_012785.1 1594439 1598221 R hypothetical protein complement(1594439..1598221) Kosmotoga olearia TBF 19.5.1 7969138 YP_002941190.1 CDS Kole_1495 NC_012785.1 1598236 1600074 R PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A; KEGG: hypothetical protein; von Willebrand factor type A complement(1598236..1600074) Kosmotoga olearia TBF 19.5.1 7969139 YP_002941191.1 CDS Kole_1496 NC_012785.1 1600080 1605200 R PFAM: PEGA domain protein; von Willebrand factor type A; SMART: von Willebrand factor type A; KEGG: aba:Acid345_2058 von Willebrand factor, type A; PEGA domain protein complement(1600080..1605200) Kosmotoga olearia TBF 19.5.1 7969140 YP_002941192.1 CDS Kole_1497 NC_012785.1 1605290 1607023 R SMART: Tetratricopeptide domain protein; KEGG: TPR Domain containing protein; hypothetical protein complement(1605290..1607023) Kosmotoga olearia TBF 19.5.1 7969141 YP_002941193.1 CDS Kole_1498 NC_012785.1 1607115 1607366 D TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; KEGG: aeh:Mlg_1971 preprotein translocase subunit SecG; preprotein translocase, SecG subunit 1607115..1607366 Kosmotoga olearia TBF 19.5.1 7969142 YP_002941194.1 CDS Kole_1499 NC_012785.1 1607377 1608570 D catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 1607377..1608570 Kosmotoga olearia TBF 19.5.1 7969143 YP_002941195.1 CDS Kole_1500 NC_012785.1 1608669 1609913 D PFAM: S-layer domain protein; KEGG: viral A-type inclusion protein; S-layer domain protein 1608669..1609913 Kosmotoga olearia TBF 19.5.1 7969144 YP_002941196.1 CDS Kole_1501 NC_012785.1 1610030 1611109 D hypothetical protein 1610030..1611109 Kosmotoga olearia TBF 19.5.1 7969145 YP_002941197.1 CDS Kole_1502 NC_012785.1 1611305 1611736 D KEGG: pne:Pnec_1234 permease YjgP/YjgQ family protein; hypothetical protein 1611305..1611736 Kosmotoga olearia TBF 19.5.1 7969146 YP_002941198.1 CDS Kole_1504 NC_012785.1 1612358 1613665 D KEGG: bha:BH3998 transposase (25); transposase (25) 1612358..1613665 Kosmotoga olearia TBF 19.5.1 7969148 YP_002941199.1 CDS Kole_1505 NC_012785.1 1613754 1614857 D PFAM: Integrase catalytic region; Resolvase helix-turn-helix domain protein; KEGG: sfu:Sfum_2833 integrase, catalytic region; Integrase catalytic region 1613754..1614857 Kosmotoga olearia TBF 19.5.1 7969149 YP_002941200.1 CDS Kole_1506 NC_012785.1 1614854 1615651 D PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: sfu:Sfum_2832 IstB domain protein ATP-binding protein; IstB domain protein ATP-binding protein 1614854..1615651 Kosmotoga olearia TBF 19.5.1 7969150 YP_002941201.1 CDS Kole_1507 NC_012785.1 1615895 1616617 D PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: bha:BH3999 transposase (26); IstB domain protein ATP-binding protein 1615895..1616617 Kosmotoga olearia TBF 19.5.1 7968584 YP_002941202.1 CDS Kole_1508 NC_012785.1 1616791 1617171 R hypothetical protein complement(1616791..1617171) Kosmotoga olearia TBF 19.5.1 7968585 YP_002941203.1 CDS Kole_1509 NC_012785.1 1617500 1619149 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: atc:AGR_L_1324 oligopeptide ABC transporter, permease protein; binding-protein-dependent transport systems inner membrane component complement(1617500..1619149) Kosmotoga olearia TBF 19.5.1 7968586 YP_002941204.1 CDS Kole_1510 NC_012785.1 1619167 1620138 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rle:RL3796 transmembrane component of ABC transporter; binding-protein-dependent transport systems inner membrane component complement(1619167..1620138) Kosmotoga olearia TBF 19.5.1 7968587 YP_002941205.1 CDS Kole_1511 NC_012785.1 1620219 1621946 R PFAM: extracellular solute-binding protein family 5; KEGG: sus:Acid_3456 extracellular solute-binding protein; extracellular solute-binding protein family 5 complement(1620219..1621946) Kosmotoga olearia TBF 19.5.1 7968588 YP_002941206.1 CDS Kole_1512 NC_012785.1 1621943 1623112 R KEGG: bba:Bd2190 oligopeptide ABC transporter, ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; peptide ABC transporter ATPase complement(1621943..1623112) Kosmotoga olearia TBF 19.5.1 7968589 YP_002941207.1 CDS Kole_1513 NC_012785.1 1623109 1624146 R KEGG: baa:BA_1731 oligopeptide transport system ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; peptide ABC transporter ATPase complement(1623109..1624146) Kosmotoga olearia TBF 19.5.1 7968590 YP_002941208.1 CDS Kole_1514 NC_012785.1 1624257 1625390 D PFAM: Threonyl/alanyl tRNA synthetase SAD; KEGG: similar to Alanyl-tRNA synthetase domain containing 1 ; K07050; Threonyl/alanyl tRNA synthetase SAD 1624257..1625390 Kosmotoga olearia TBF 19.5.1 7968591 YP_002941209.1 CDS Kole_1515 NC_012785.1 1625387 1626742 D TIGRFAM: replicative DNA helicase; PFAM: DnaB domain protein helicase domain protein; KEGG: sat:SYN_00640 replicative DNA helicase; replicative DNA helicase 1625387..1626742 Kosmotoga olearia TBF 19.5.1 7968592 YP_002941210.1 CDS Kole_1516 NC_012785.1 1627341 1628096 D PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: aba:Acid345_3570 ABC transporter, ATPase subunit; ABC transporter 1627341..1628096 Kosmotoga olearia TBF 19.5.1 7968593 YP_002941211.1 CDS Kole_1517 NC_012785.1 1628103 1629659 D KEGG: hypothetical protein; hypothetical protein 1628103..1629659 Kosmotoga olearia TBF 19.5.1 7968594 YP_002941212.1 CDS Kole_1518 NC_012785.1 1629665 1630099 D KEGG: GOLGA2; golgi autoantigen, golgin subfamily a, 2; hypothetical protein 1629665..1630099 Kosmotoga olearia TBF 19.5.1 7968595 YP_002941213.1 CDS Kole_1519 NC_012785.1 1630138 1632948 R PFAM: O-antigen polymerase; KEGG: vfm:VFMJ11_A1152 secreted polysaccharide polymerase; O-antigen polymerase complement(1630138..1632948) Kosmotoga olearia TBF 19.5.1 7968596 YP_002941214.1 CDS Kole_1520 NC_012785.1 1632991 1633410 R PFAM: protein of unknown function UPF0047; KEGG: mgm:Mmc1_3648 protein of unknown function UPF0047; hypothetical protein complement(1632991..1633410) Kosmotoga olearia TBF 19.5.1 7968597 YP_002941215.1 CDS Kole_1521 NC_012785.1 1633410 1633688 R KEGG: tmz:Tmz1t_2034 cell division topological specificity factor MinE; cell division topological specificity factor MinE complement(1633410..1633688) Kosmotoga olearia TBF 19.5.1 7968598 YP_002941216.1 CDS Kole_1522 NC_012785.1 1633705 1634520 R TIGRFAM: septum site-determining protein MinD; PFAM: Cobyrinic acid ac-diamide synthase; KEGG: sfu:Sfum_1281 septum site-determining protein MinD; septum site-determining protein MinD complement(1633705..1634520) Kosmotoga olearia TBF 19.5.1 7968599 YP_002941217.1 CDS Kole_1523 NC_012785.1 1634583 1635764 R KEGG: glo:Glov_1090 protein of unknown function Met10; hypothetical protein complement(1634583..1635764) Kosmotoga olearia TBF 19.5.1 7968600 YP_002941218.1 CDS Kole_1524 NC_012785.1 1635746 1636861 R PFAM: iron-containing alcohol dehydrogenase; KEGG: pca:Pcar_2506 alcohol dehydrogenase, class IV; iron-containing alcohol dehydrogenase complement(1635746..1636861) Kosmotoga olearia TBF 19.5.1 7968601 YP_002941219.1 CDS Kole_1525 NC_012785.1 1636881 1637945 R PFAM: polysaccharide pyruvyl transferase; KEGG: baa:BA_1468 hypothetical protein; polysaccharide pyruvyl transferase complement(1636881..1637945) Kosmotoga olearia TBF 19.5.1 7968602 YP_002941220.1 CDS Kole_1526 NC_012785.1 1638046 1639248 D catalyzes the interconversion of 3-phosphoglycerate and 2-phosphoglycerate; this enzyme does not require the cofactor 2,3-bisphosphoglycerate as a phosphate donor; BPG-independent PGAM; aPGAM; cofactor-independent phosphoglycerate mutase 1638046..1639248 Kosmotoga olearia TBF 19.5.1 7968603 YP_002941221.1 CDS Kole_1527 NC_012785.1 1639267 1640628 D TIGRFAM: ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein; KEGG: ppd:Ppro_1379 DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein 1639267..1640628 Kosmotoga olearia TBF 19.5.1 7968604 YP_002941222.1 CDS Kole_1528 NC_012785.1 1640580 1641026 R PFAM: ferric-uptake regulator; KEGG: bha:BH1527 ferric uptake regulation protein; ferric uptake regulator, Fur family complement(1640580..1641026) Kosmotoga olearia TBF 19.5.1 7968605 YP_002941223.1 CDS nusA NC_012785.1 1641126 1642154 R modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA complement(1641126..1642154) Kosmotoga olearia TBF 19.5.1 7968606 YP_002941224.1 CDS Kole_1530 NC_012785.1 1642173 1642676 R PFAM: protein of unknown function DUF150; KEGG: gur:Gura_1898 hypothetical protein; hypothetical protein complement(1642173..1642676) Kosmotoga olearia TBF 19.5.1 7968607 YP_002941225.1 CDS Kole_1531 NC_012785.1 1642875 1643810 D KEGG: tdn:Suden_1346 sulfonate/nitrate transport system substrate-binding protein; ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components-like protein 1642875..1643810 Kosmotoga olearia TBF 19.5.1 7968608 YP_002941226.1 CDS Kole_1532 NC_012785.1 1643800 1644549 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eba:ebA2114 ABC transporter, permease protein; binding-protein-dependent transport systems inner membrane component 1643800..1644549 Kosmotoga olearia TBF 19.5.1 7968609 YP_002941227.1 CDS Kole_1533 NC_012785.1 1644533 1645222 D PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: aci:ACIAD0034 alkanesulfonate ABC transporter ATP-binding protein; ABC transporter 1644533..1645222 Kosmotoga olearia TBF 19.5.1 7968610 YP_002941228.1 CDS Kole_1534 NC_012785.1 1645294 1645851 D PFAM: protein of unknown function DUF177; KEGG: sat:SYN_02362 zinc finger protein; hypothetical protein 1645294..1645851 Kosmotoga olearia TBF 19.5.1 7968611 YP_002941229.1 CDS rpmF NC_012785.1 1645854 1646036 D some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1645854..1646036 Kosmotoga olearia TBF 19.5.1 7968612 YP_002941230.1 CDS Kole_1536 NC_012785.1 1646033 1647040 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 1646033..1647040 Kosmotoga olearia TBF 19.5.1 7968613 YP_002941231.1 CDS Kole_1537 NC_012785.1 1647043 1648869 D Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 1647043..1648869 Kosmotoga olearia TBF 19.5.1 7968614 YP_002941232.1 CDS Kole_1538 NC_012785.1 1648903 1649253 D PFAM: Iojap-related protein; KEGG: aci:ACIAD3076 hypothetical protein; Iojap-related protein 1648903..1649253 Kosmotoga olearia TBF 19.5.1 7968615 YP_002941233.1 CDS rpsB NC_012785.1 1649349 1650176 D one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 1649349..1650176 Kosmotoga olearia TBF 19.5.1 7968616 YP_002941234.1 CDS Kole_1540 NC_012785.1 1650262 1651584 D catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 1650262..1651584 Kosmotoga olearia TBF 19.5.1 7968617 YP_002941235.1 CDS Kole_1541 NC_012785.1 1651600 1651887 R PFAM: Exonuclease VII small subunit; KEGG: bha:BH2782 exodeoxyribonuclease VII (small subunit); Exonuclease VII small subunit complement(1651600..1651887) Kosmotoga olearia TBF 19.5.1 7968618 YP_002941236.1 CDS Kole_1542 NC_012785.1 1651895 1653424 R PFAM: Exonuclease VII large subunit; KEGG: ecg:E2348C_2784 exonuclease VII, large subunit; Exodeoxyribonuclease VII complement(1651895..1653424) Kosmotoga olearia TBF 19.5.1 7968619 YP_002941237.1 CDS Kole_1543 NC_012785.1 1653511 1653858 D KEGG: bha:BH1689 aspartate alpha-decarboxylase; TIGRFAM: aspartate 1-decarboxylase; PFAM: aspartate decarboxylase; aspartate 1-decarboxylase 1653511..1653858 Kosmotoga olearia TBF 19.5.1 7968620 YP_002941238.1 CDS Kole_1544 NC_012785.1 1653860 1655140 D TIGRFAM: cytidyltransferase-related domain protein; PFAM: protein of unknown function DUF795; KEGG: bsu:BSU15060 hypothetical protein; cytidyltransferase-related domain protein 1653860..1655140 Kosmotoga olearia TBF 19.5.1 7968621 YP_002941239.1 CDS Kole_1545 NC_012785.1 1655157 1657436 D KEGG: bar:GBAA4006 primosome assembly protein PriA; TIGRFAM: primosomal protein N'; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; type III restriction protein res subunit; SMART: DEAD-like helicase ; helicase domain protein; primosomal protein N' 1655157..1657436 Kosmotoga olearia TBF 19.5.1 7968622 YP_002941240.1 CDS Kole_1546 NC_012785.1 1657454 1658659 R KEGG: jan:Jann_3293 oligopeptide/dipeptide ABC transporter, ATP-binding protein-like; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; peptide ABC transporter ATPase complement(1657454..1658659) Kosmotoga olearia TBF 19.5.1 7968623 YP_002941241.1 CDS Kole_1547 NC_012785.1 1658656 1659669 R KEGG: bar:GBAA4733 oligopeptide ABC transporter, ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; peptide ABC transporter ATPase complement(1658656..1659669) Kosmotoga olearia TBF 19.5.1 7968624 YP_002941242.1 CDS Kole_1548 NC_012785.1 1659682 1660566 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA0135 ABC transporter permease protein; binding-protein-dependent transport systems inner membrane component complement(1659682..1660566) Kosmotoga olearia TBF 19.5.1 7968625 YP_002941243.1 CDS Kole_1549 NC_012785.1 1660580 1661614 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mes:Meso_0066 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component complement(1660580..1661614) Kosmotoga olearia TBF 19.5.1 7968626 YP_002941244.1 CDS Kole_1550 NC_012785.1 1661754 1663592 R PFAM: extracellular solute-binding protein family 5; KEGG: apl:APL_0063 periplasmic dipeptide transport protein; extracellular solute-binding protein family 5 complement(1661754..1663592) Kosmotoga olearia TBF 19.5.1 7968627 YP_002941245.1 CDS Kole_1551 NC_012785.1 1663720 1664697 R PFAM: inner-membrane translocator; KEGG: baa:BA_4395 branched-chain amino acid transport system / permease component; inner-membrane translocator complement(1663720..1664697) Kosmotoga olearia TBF 19.5.1 7968628 YP_002941246.1 CDS Kole_1552 NC_012785.1 1664694 1665749 R PFAM: inner-membrane translocator; KEGG: sme:SM_b20126 sugar ABC transporter permease protein; inner-membrane translocator complement(1664694..1665749) Kosmotoga olearia TBF 19.5.1 7968629 YP_002941247.1 CDS Kole_1553 NC_012785.1 1665746 1667431 R PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bsu:BSU31550 hypothetical protein; ABC transporter complement(1665746..1667431) Kosmotoga olearia TBF 19.5.1 7968630 YP_002941248.1 CDS Kole_1554 NC_012785.1 1667454 1668479 R PFAM: basic membrane lipoprotein; KEGG: sfu:Sfum_2515 basic membrane lipoprotein; basic membrane lipoprotein complement(1667454..1668479) Kosmotoga olearia TBF 19.5.1 7968631 YP_002941249.1 CDS Kole_1555 NC_012785.1 1668476 1669108 R hypothetical protein complement(1668476..1669108) Kosmotoga olearia TBF 19.5.1 7968632 YP_002941250.1 CDS Kole_1556 NC_012785.1 1669105 1670802 R hypothetical protein complement(1669105..1670802) Kosmotoga olearia TBF 19.5.1 7968633 YP_002941251.1 CDS Kole_1557 NC_012785.1 1670829 1671452 R TIGRFAM: uridine kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: mxa:MXAN_4159 uridine kinase; uridine kinase complement(1670829..1671452) Kosmotoga olearia TBF 19.5.1 7968634 YP_002941252.1 CDS Kole_1558 NC_012785.1 1671452 1672096 R modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor Rex complement(1671452..1672096) Kosmotoga olearia TBF 19.5.1 7968635 YP_002941253.1 CDS Kole_1559 NC_012785.1 1672329 1672568 D hypothetical protein 1672329..1672568 Kosmotoga olearia TBF 19.5.1 7968636 YP_002941254.1 CDS Kole_1560 NC_012785.1 1672556 1673095 D KEGG: dat:HRM2_18430 hypothetical protein; hypothetical protein 1672556..1673095 Kosmotoga olearia TBF 19.5.1 7968637 YP_002941255.1 CDS Kole_1561 NC_012785.1 1673092 1674393 D KEGG: geo:Geob_0920 MiaB-like tRNA modifying enzyme YliG; TIGRFAM: MiaB-like tRNA modifying enzyme YliG; RNA modification enzyme, MiaB family; PFAM: Protein of unknown function UPF0004 ; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; MiaB-like tRNA modifying enzyme YliG 1673092..1674393 Kosmotoga olearia TBF 19.5.1 7968638 YP_002941256.1 CDS Kole_1562 NC_012785.1 1674380 1674919 D TIGRFAM: CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; KEGG: lip:LI0373 phosphatidylglycerophosphate synthase; CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase 1674380..1674919 Kosmotoga olearia TBF 19.5.1 7968639 YP_002941257.1 CDS Kole_1563 NC_012785.1 1674861 1675487 D TIGRFAM: 2'-5' RNA ligase; PFAM: Phosphoesterase HXTX; KEGG: sfu:Sfum_2529 2'-5' RNA ligase; 2'-5' RNA ligase 1674861..1675487 Kosmotoga olearia TBF 19.5.1 7968640 YP_002941258.1 CDS Kole_1564 NC_012785.1 1675477 1676544 D KEGG: tcx:Tcr_1592 RecA protein; TIGRFAM: recA protein; PFAM: RecA domain protein; SMART: AAA ATPase; recA protein 1675477..1676544 Kosmotoga olearia TBF 19.5.1 7968641 YP_002941259.1 CDS Kole_1565 NC_012785.1 1676567 1677016 D PFAM: regulatory protein RecX; KEGG: bha:BH0924 recombination regulator RecX; regulatory protein RecX 1676567..1677016 Kosmotoga olearia TBF 19.5.1 7968642 YP_002941260.1 CDS Kole_1566 NC_012785.1 1677097 1678629 D protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP; phosphodiesterase 1677097..1678629 Kosmotoga olearia TBF 19.5.1 7968643 YP_002941261.1 CDS Kole_1567 NC_012785.1 1678805 1680214 D TIGRFAM: tRNA(Ile)-lysidine synthetase; PFAM: PP-loop domain protein; KEGG: dal:Dalk_4273 tRNA(Ile)-lysidine synthetase; tRNA(Ile)-lysidine synthetase 1678805..1680214 Kosmotoga olearia TBF 19.5.1 7968645 YP_002941262.1 CDS Kole_1568 NC_012785.1 1680219 1682156 D KEGG: baa:BA_0654 peptidase_M41, peptidase family M41; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; peptidase M41 FtsH extracellular; AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; ATP-dependent metalloprotease FtsH 1680219..1682156 Kosmotoga olearia TBF 19.5.1 7968646 YP_002941263.1 CDS Kole_1569 NC_012785.1 1682137 1682535 D hypothetical protein 1682137..1682535 Kosmotoga olearia TBF 19.5.1 7968647 YP_002941264.1 CDS Kole_1570 NC_012785.1 1682522 1683970 D PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: gme:Gmet_0418 radical SAM family protein; Radical SAM domain protein 1682522..1683970 Kosmotoga olearia TBF 19.5.1 7968648 YP_002941265.1 CDS Kole_1571 NC_012785.1 1683977 1684696 D PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: sat:SYN_00981 response regulator; two component transcriptional regulator, winged helix family 1683977..1684696 Kosmotoga olearia TBF 19.5.1 7968649 YP_002941266.1 CDS Kole_1572 NC_012785.1 1684700 1685953 D KEGG: bha:BH3156 two-component sensor histidine kinase involved in phosphate regulation; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAS/PAC sensor signal transduction histidine kinase 1684700..1685953 Kosmotoga olearia TBF 19.5.1 7968650 YP_002941267.1 CDS Kole_1573 NC_012785.1 1685950 1687251 D KEGG: baa:BA_4765 glycosyl transferase family, a/b domain; TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: Pyrimidine nucleoside phosphorylase domain; glycosyl transferase family 3; Glycosyl transferase, family 3-like; pyrimidine-nucleoside phosphorylase 1685950..1687251 Kosmotoga olearia TBF 19.5.1 7968651 YP_002941268.1 CDS Kole_1574 NC_012785.1 1687268 1688944 D KEGG: hypothetical protein; hypothetical protein 1687268..1688944 Kosmotoga olearia TBF 19.5.1 7968652 YP_002941269.1 CDS Kole_1575 NC_012785.1 1688964 1691027 D TIGRFAM: translation elongation factor G; small GTP-binding protein; PFAM: elongation factor G domain IV; protein synthesis factor GTP-binding; elongation factor G domain protein; elongation factor Tu domain 2 protein; KEGG: nis:NIS_0272 elongation factor G; translation elongation factor G 1688964..1691027 Kosmotoga olearia TBF 19.5.1 7968653 YP_002941270.1 CDS Kole_1576 NC_012785.1 1691085 1692359 D PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: pat:Patl_2810 alpha amylase, catalytic region; alpha amylase catalytic region 1691085..1692359 Kosmotoga olearia TBF 19.5.1 7968654 YP_002941271.1 CDS Kole_1577 NC_012785.1 1692371 1692652 D PFAM: protein of unknown function DUF503; KEGG: dat:HRM2_07640 hypothetical protein; hypothetical protein 1692371..1692652 Kosmotoga olearia TBF 19.5.1 7968655 YP_002941272.1 CDS Kole_1578 NC_012785.1 1692630 1693265 D PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: bha:BH1327 hypothetical protein; metal dependent phosphohydrolase 1692630..1693265 Kosmotoga olearia TBF 19.5.1 7968656 YP_002941273.1 CDS Kole_1579 NC_012785.1 1693234 1693950 D hypothetical protein 1693234..1693950 Kosmotoga olearia TBF 19.5.1 7968657 YP_002941274.1 CDS Kole_1580 NC_012785.1 1693958 1695142 D TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator; KEGG: bsu:BSU35520 hypothetical protein; cell envelope-related transcriptional attenuator 1693958..1695142 Kosmotoga olearia TBF 19.5.1 7968658 YP_002941275.1 CDS Kole_1581 NC_012785.1 1695139 1696242 D PFAM: protein of unknown function DUF214; KEGG: mfa:Mfla_2095 LolC/E family lipoprotein releasing system, transmembrane protein; hypothetical protein 1695139..1696242 Kosmotoga olearia TBF 19.5.1 7968659 YP_002941276.1 CDS Kole_1582 NC_012785.1 1696235 1696894 D PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: abu:Abu_0440 ABC transporter, ATP-binding protein; ABC transporter 1696235..1696894 Kosmotoga olearia TBF 19.5.1 7968660 YP_002941277.1 CDS Kole_1583 NC_012785.1 1696891 1697847 D PFAM: GAF domain protein; KEGG: aba:Acid345_2653 GAF sensor protein; GAF sensor protein 1696891..1697847 Kosmotoga olearia TBF 19.5.1 7968661 YP_002941278.1 CDS Kole_1584 NC_012785.1 1698015 1699175 D PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: mag:amb1388 diaminopimelate decarboxylase; Ornithine decarboxylase 1698015..1699175 Kosmotoga olearia TBF 19.5.1 7968662 YP_002941279.1 CDS Kole_1585 NC_012785.1 1699189 1700526 R KEGG: sun:SUN_0585 hypothetical protein; hypothetical protein complement(1699189..1700526) Kosmotoga olearia TBF 19.5.1 7968663 YP_002941280.1 CDS Kole_1586 NC_012785.1 1700536 1701393 R PFAM: Rhomboid family protein; KEGG: aba:Acid345_1881 rhomboid-like protein; Rhomboid family protein complement(1700536..1701393) Kosmotoga olearia TBF 19.5.1 7968664 YP_002941281.1 CDS Kole_1587 NC_012785.1 1701407 1702318 R hypothetical protein complement(1701407..1702318) Kosmotoga olearia TBF 19.5.1 7967819 YP_002941282.1 CDS Kole_1588 NC_012785.1 1702315 1704000 R PFAM: Fibronectin-binding A domain protein; protein of unknown function DUF814; KEGG: bsu:BSU15640 hypothetical protein; Fibronectin-binding A domain protein complement(1702315..1704000) Kosmotoga olearia TBF 19.5.1 7967820 YP_002941283.1 CDS Kole_1589 NC_012785.1 1703990 1704862 R KEGG: sus:Acid_7097 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; PFAM: GHMP kinase; GHMP kinase domain protein; 4-diphosphocytidyl-2C-methyl-D-erythritol kinase complement(1703990..1704862) Kosmotoga olearia TBF 19.5.1 7967821 YP_002941284.1 CDS Kole_1590 NC_012785.1 1704823 1705404 R PFAM: NUDIX hydrolase; KEGG: bsu:BSU17400 hypothetical protein; NUDIX hydrolase complement(1704823..1705404) Kosmotoga olearia TBF 19.5.1 7967822 YP_002941285.1 CDS Kole_1591 NC_012785.1 1705420 1708020 R PFAM: CBS domain containing protein; Polynucleotide adenylyltransferase region; phosphoesterase RecJ domain protein; SMART: CBS domain containing protein; KEGG: gsu:GSU1581 polyA polymerase family protein; CBS domain containing protein complement(1705420..1708020) Kosmotoga olearia TBF 19.5.1 7967823 YP_002941286.1 CDS Kole_1592 NC_012785.1 1708017 1709357 R PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; response regulator receiver; SMART: response regulator receiver; AAA ATPase; KEGG: glo:Glov_1166 two component, sigma54 specific, transcriptional regulator, Fis family; two component, sigma54 specific, transcriptional regulator, Fis family complement(1708017..1709357) Kosmotoga olearia TBF 19.5.1 7967824 YP_002941287.1 CDS Kole_1593 NC_012785.1 1709359 1710645 R PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: spc:Sputcn32_2579 PAS/PAC sensor signal transduction histidine kinase; histidine kinase complement(1709359..1710645) Kosmotoga olearia TBF 19.5.1 7967825 YP_002941288.1 CDS Kole_1594 NC_012785.1 1710623 1711417 R PFAM: protein of unknown function DUF62; KEGG: sfu:Sfum_1405 protein of unknown function DUF62; hypothetical protein complement(1710623..1711417) Kosmotoga olearia TBF 19.5.1 7967826 YP_002941289.1 CDS Kole_1595 NC_012785.1 1711398 1711790 R PFAM: protein of unknown function DUF123; KEGG: tgr:Tgr7_0278 protein of unknown function DUF123; hypothetical protein complement(1711398..1711790) Kosmotoga olearia TBF 19.5.1 7967827 YP_002941290.1 CDS Kole_1596 NC_012785.1 1711928 1712995 D PFAM: alanine racemase domain protein; KEGG: mlo:mlr5700 hypothetical protein; alanine racemase domain protein 1711928..1712995 Kosmotoga olearia TBF 19.5.1 7967828 YP_002941291.1 CDS Kole_1597 NC_012785.1 1713024 1713458 R PFAM: CBS domain containing protein; SMART: CBS domain containing protein; KEGG: hypothetical protein; CBS domain containing membrane protein complement(1713024..1713458) Kosmotoga olearia TBF 19.5.1 7967829 YP_002941292.1 CDS Kole_1598 NC_012785.1 1713461 1714744 R PFAM: Citrate transporter; Arsenical pump membrane protein; KEGG: baa:BA_0017 arsenical pump membrane protein; Citrate transporter complement(1713461..1714744) Kosmotoga olearia TBF 19.5.1 7967830 YP_002941293.1 CDS Kole_1599 NC_012785.1 1714859 1716247 D KEGG: sat:SYN_01706 endopeptidase; TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; protease Do 1714859..1716247 Kosmotoga olearia TBF 19.5.1 7967831 YP_002941294.1 CDS Kole_1600 NC_012785.1 1716372 1717151 R PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: spe:Spro_3426 ABC transporter-related protein; ABC transporter complement(1716372..1717151) Kosmotoga olearia TBF 19.5.1 7967832 YP_002941295.1 CDS Kole_1601 NC_012785.1 1717144 1718046 R PFAM: transport system permease protein; ABC-3 protein; KEGG: iron ion transport system, inner membrane component ; K02015 iron complex transport system permease protein; transport system permease protein complement(1717144..1718046) Kosmotoga olearia TBF 19.5.1 7967833 YP_002941296.1 CDS Kole_1602 NC_012785.1 1718139 1719032 R PFAM: periplasmic binding protein; KEGG: sat:SYN_01423 ABC-type transporter cobalamide binding protein; periplasmic binding protein complement(1718139..1719032) Kosmotoga olearia TBF 19.5.1 7967834 YP_002941297.1 CDS Kole_1603 NC_012785.1 1719260 1721068 R TIGRFAM: DNA mismatch repair protein MutL; PFAM: MutL dimerisation; DNA mismatch repair protein domain protein; ATP-binding region ATPase domain protein; KEGG: pca:Pcar_1304 DNA mismatch repair enzyme; DNA mismatch repair protein MutL complement(1719260..1721068) Kosmotoga olearia TBF 19.5.1 7967835 YP_002941298.1 CDS Kole_1604 NC_012785.1 1721065 1721817 R TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: afw:Anae109_2230 RNA methyltransferase; RNA methyltransferase, TrmH family, group 3 complement(1721065..1721817) Kosmotoga olearia TBF 19.5.1 7967836 YP_002941299.1 CDS Kole_1605 NC_012785.1 1721771 1722208 R KEGG: baa:BA_0679 RIBOc, ribonuclease III family; hypothetical protein complement(1721771..1722208) Kosmotoga olearia TBF 19.5.1 7967837 YP_002941300.1 CDS alaS NC_012785.1 1722201 1724822 R Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase complement(1722201..1724822) Kosmotoga olearia TBF 19.5.1 7967838 YP_002941301.1 CDS Kole_1607 NC_012785.1 1724841 1725695 R PFAM: phosphatidate cytidylyltransferase; KEGG: baa:BA_4430 cytidylyltrans, Phosphatidate cytidylyltransferase; phosphatidate cytidylyltransferase complement(1724841..1725695) Kosmotoga olearia TBF 19.5.1 7967839 YP_002941302.1 CDS Kole_1608 NC_012785.1 1725685 1726380 R KEGG: sat:SYN_00918 undecaprenyl pyrophosphate synthetase; TIGRFAM: undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase; UDP diphosphate synthase complement(1725685..1726380) Kosmotoga olearia TBF 19.5.1 7967840 YP_002941303.1 CDS frr NC_012785.1 1726386 1726943 R Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor complement(1726386..1726943) Kosmotoga olearia TBF 19.5.1 7967841 YP_002941304.1 CDS Kole_1610 NC_012785.1 1727117 1727488 D TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: lpc:LPC_1485 transmembrane protein YajC, preprotein translocase subunit; preprotein translocase, YajC subunit 1727117..1727488 Kosmotoga olearia TBF 19.5.1 7967842 YP_002941305.1 CDS Kole_1611 NC_012785.1 1727571 1729076 D TIGRFAM: protein-export membrane protein SecD; protein-export membrane protein, SecD/SecF family; PFAM: SecD/SecF/SecDF export membrane protein; KEGG: rce:RC1_1042 protein-export membrane protein SecD; protein-export membrane protein SecD 1727571..1729076 Kosmotoga olearia TBF 19.5.1 7967843 YP_002941306.1 CDS Kole_1612 NC_012785.1 1729073 1729987 D TIGRFAM: protein-export membrane protein SecF; protein-export membrane protein, SecD/SecF family; PFAM: SecD/SecF/SecDF export membrane protein; KEGG: nam:NAMH_1481 protein-export membrane protein SecF; protein-export membrane protein SecF 1729073..1729987 Kosmotoga olearia TBF 19.5.1 7967844 YP_002941307.1 CDS Kole_1613 NC_012785.1 1730164 1731090 D SMART: phospholipase D/Transphosphatidylase; KEGG: ypp:YPDSF_4129 endonuclease; phospholipase D/Transphosphatidylase 1730164..1731090 Kosmotoga olearia TBF 19.5.1 7967846 YP_002941308.1 CDS Kole_1614 NC_012785.1 1731080 1732816 D KEGG: cbd:CBUD_0922 glutamine-dependent NAD(+) synthetase; TIGRFAM: NAD+ synthetase; PFAM: NAD synthase; Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; NAD+ synthetase 1731080..1732816 Kosmotoga olearia TBF 19.5.1 7967847 YP_002941309.1 CDS Kole_1615 NC_012785.1 1732809 1733606 D TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; Haloacid dehalogenase domain protein hydrolase; sucrose-6F-phosphate phosphohydrolase; KEGG: hypothetical protein; Cof-like hydrolase 1732809..1733606 Kosmotoga olearia TBF 19.5.1 7967848 YP_002941310.1 CDS Kole_1616 NC_012785.1 1733603 1734727 R hypothetical protein complement(1733603..1734727) Kosmotoga olearia TBF 19.5.1 7967849 YP_002941311.1 CDS Kole_1617 NC_012785.1 1734807 1736624 R KEGG: azo:azo2712 GGDEF/PAS/PAC-domain-containing protein; TIGRFAM: PAS sensor protein; PFAM: PAS fold domain protein; SMART: PAS domain containing protein; PAS/PAC sensor protein complement(1734807..1736624) Kosmotoga olearia TBF 19.5.1 7967850 YP_002941312.1 CDS Kole_1618 NC_012785.1 1737109 1737861 D KEGG: rpt:Rpal_5127 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 1737109..1737861 Kosmotoga olearia TBF 19.5.1 7967851 YP_002941313.1 CDS Kole_1619 NC_012785.1 1738023 1739474 R acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein; glycine dehydrogenase subunit 2 complement(1738023..1739474) Kosmotoga olearia TBF 19.5.1 7967853 YP_002941314.1 CDS Kole_1620 NC_012785.1 1739471 1740820 R acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 2 to form the P protein; glycine dehydrogenase subunit 1 complement(1739471..1740820) Kosmotoga olearia TBF 19.5.1 7967854 YP_002941315.1 CDS Kole_1621 NC_012785.1 1740822 1741193 R part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H complement(1740822..1741193) Kosmotoga olearia TBF 19.5.1 7967855 YP_002941316.1 CDS Kole_1622 NC_012785.1 1741213 1742319 R TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: bha:BH2816 glycine cleavage system aminomethyltransferase T; glycine cleavage system T protein complement(1741213..1742319) Kosmotoga olearia TBF 19.5.1 7967856 YP_002941317.1 CDS Kole_1623 NC_012785.1 1742323 1742541 R hypothetical protein complement(1742323..1742541) Kosmotoga olearia TBF 19.5.1 7967857 YP_002941318.1 CDS Kole_1624 NC_012785.1 1742693 1743655 D catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 1742693..1743655 Kosmotoga olearia TBF 19.5.1 7967858 YP_002941319.1 CDS Kole_1625 NC_012785.1 1743675 1745093 D KEGG: bha:BH3163 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; pyruvate kinase 1743675..1745093 Kosmotoga olearia TBF 19.5.1 7967859 YP_002941320.1 CDS groES NC_012785.1 1745333 1745602 D 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 1745333..1745602 Kosmotoga olearia TBF 19.5.1 7967860 YP_002941321.1 CDS groEL NC_012785.1 1745618 1747237 D 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 1745618..1747237 Kosmotoga olearia TBF 19.5.1 7967861 YP_002941322.1 CDS Kole_1628 NC_012785.1 1747542 1747673 D hypothetical protein 1747542..1747673 Kosmotoga olearia TBF 19.5.1 7967862 YP_002941323.1 CDS Kole_1629 NC_012785.1 1747920 1748930 D PFAM: glycosyl transferase family 2; KEGG: nis:NIS_1251 glycosyl transferase; glycosyl transferase family 2 1747920..1748930 Kosmotoga olearia TBF 19.5.1 7967863 YP_002941324.1 CDS Kole_1630 NC_012785.1 1748968 1750083 D PFAM: glycosyl transferase group 1; KEGG: abu:Abu_0691 glycosyltransferase; glycosyl transferase group 1 1748968..1750083 Kosmotoga olearia TBF 19.5.1 7967864 YP_002941325.1 CDS Kole_1631 NC_012785.1 1750101 1751174 D KEGG: aav:Aave_0953 UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; UDP-N-acetylglucosamine 2-epimerase 1750101..1751174 Kosmotoga olearia TBF 19.5.1 7967865 YP_002941326.1 CDS Kole_1632 NC_012785.1 1751334 1752533 D PFAM: glycosyl transferase group 1; KEGG: net:Neut_1096 glycosyl transferase, group 1; glycosyl transferase group 1 1751334..1752533 Kosmotoga olearia TBF 19.5.1 7967866 YP_002941327.1 CDS Kole_1633 NC_012785.1 1752549 1753697 D PFAM: glycosyl transferase group 1; KEGG: eci:UTI89_C2303 galactosyltransferase WbgM; glycosyl transferase group 1 1752549..1753697 Kosmotoga olearia TBF 19.5.1 7967867 YP_002941328.1 CDS Kole_1634 NC_012785.1 1753729 1754913 D KEGG: baa:BA_1468 hypothetical protein; hypothetical protein 1753729..1754913 Kosmotoga olearia TBF 19.5.1 7967868 YP_002941329.1 CDS Kole_1635 NC_012785.1 1754938 1756443 D PFAM: virulence factor MVIN family protein; polysaccharide biosynthesis protein; multi antimicrobial extrusion protein MatE; KEGG: sat:SYN_00104 virulence factor protein; virulence factor MVIN family protein 1754938..1756443 Kosmotoga olearia TBF 19.5.1 7967869 YP_002941330.1 CDS Kole_1636 NC_012785.1 1756685 1757362 D PFAM: regulatory protein MarR; KEGG: dvm:DvMF_1831 MarR family transcriptional regulator; MarR family transcriptional regulator 1756685..1757362 Kosmotoga olearia TBF 19.5.1 7967870 YP_002941331.1 CDS Kole_1637 NC_012785.1 1757343 1758608 D PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: aba:Acid345_4343 DegT/DnrJ/EryC1/StrS aminotransferase; DegT/DnrJ/EryC1/StrS aminotransferase 1757343..1758608 Kosmotoga olearia TBF 19.5.1 7967871 YP_002941332.1 CDS Kole_1638 NC_012785.1 1758613 1759338 D PFAM: transferase hexapeptide repeat containing protein; KEGG: sus:Acid_5707 WxcM domain-containing protein; transferase hexapeptide repeat containing protein 1758613..1759338 Kosmotoga olearia TBF 19.5.1 7967872 YP_002941333.1 CDS Kole_1639 NC_012785.1 1759826 1761130 D KEGG: mxa:MXAN_2689 lipopolysaccharide biosynthesis protein; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase ; 6-phosphogluconate dehydrogenase NAD-binding; nucleotide sugar dehydrogenase 1759826..1761130 Kosmotoga olearia TBF 19.5.1 7967873 YP_002941334.1 CDS Kole_1640 NC_012785.1 1761179 1761553 D PFAM: S23 ribosomal protein; KEGG: aca:ACP_1829 hypothetical protein; S23 ribosomal protein 1761179..1761553 Kosmotoga olearia TBF 19.5.1 7967874 YP_002941335.1 CDS Kole_1641 NC_012785.1 1761604 1762725 D PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: eli:ELI_13345 lipopolysaccharide biosynthesis protein; oxidoreductase domain protein 1761604..1762725 Kosmotoga olearia TBF 19.5.1 7967875 YP_002941336.1 CDS Kole_1642 NC_012785.1 1762847 1763242 R hypothetical protein complement(1762847..1763242) Kosmotoga olearia TBF 19.5.1 7967876 YP_002941337.1 CDS Kole_1643 NC_012785.1 1763396 1764034 D PFAM: class II aldolase/adducin family protein; KEGG: ppd:Ppro_2543 class II aldolase/adducin family protein; class II aldolase/adducin family protein 1763396..1764034 Kosmotoga olearia TBF 19.5.1 7967877 YP_002941338.1 CDS Kole_1645 NC_012785.1 1766470 1766730 D TIGRFAM: ribosomal protein S15; PFAM: ribosomal protein S15; KEGG: gbm:Gbem_1307 ribosomal protein S15; 30S ribosomal protein S15 1766470..1766730 Kosmotoga olearia TBF 19.5.1 7967879 YP_002941339.1 CDS Kole_1646 NC_012785.1 1766834 1769047 D KEGG: bsu:BSU16690 polynucleotide phosphorylase/polyadenylase; PFAM: 3' exoribonuclease; Exoribonuclease, phosphorolytic domain 2; RNA binding S1 domain protein; KH type 1 domain protein; SMART: RNA binding S1 domain protein; KH domain protein; polynucleotide phosphorylase/polyadenylase 1766834..1769047 Kosmotoga olearia TBF 19.5.1 7967880 YP_002941340.1 CDS Kole_1647 NC_012785.1 1769044 1770321 D PFAM: peptidase M16 domain protein; KEGG: bha:BH2405 processing protease; peptidase M16 domain protein 1769044..1770321 Kosmotoga olearia TBF 19.5.1 7967881 YP_002941341.1 CDS Kole_1648 NC_012785.1 1776041 1776889 D PFAM: GCN5-related N-acetyltransferase; KEGG: rce:RC1_2464 acetyltransferase, GNAT family; GCN5-related N-acetyltransferase 1776041..1776889 Kosmotoga olearia TBF 19.5.1 7967887 YP_002941342.1 CDS Kole_1649 NC_012785.1 1776909 1777775 D KEGG: cju:C8J_0274 pantoate--beta-alanine ligase; TIGRFAM: pantoate/beta-alanine ligase; PFAM: Pantoate-beta-alanine ligase; pantoate/beta-alanine ligase 1776909..1777775 Kosmotoga olearia TBF 19.5.1 7967888 YP_002941343.1 CDS Kole_1650 NC_012785.1 1777761 1778849 R PFAM: cyclic nucleotide-binding; KEGG: hypothetical protein; Crp/Fnr family transcriptional regulator complement(1777761..1778849) Kosmotoga olearia TBF 19.5.1 7967889 YP_002941344.1 CDS Kole_1651 NC_012785.1 1778916 1780139 R AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase complement(1778916..1780139) Kosmotoga olearia TBF 19.5.1 7967890 YP_002941345.1 CDS Kole_1652 NC_012785.1 1780160 1781104 R KEGG: hpy:HP0176 fructose-bisphosphate aldolase; TIGRFAM: fructose-1,6-bisphosphate aldolase, class II; ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; fructose-1,6-bisphosphate aldolase, class II complement(1780160..1781104) Kosmotoga olearia TBF 19.5.1 7967891 YP_002941346.1 CDS Kole_1653 NC_012785.1 1781182 1782213 R TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: gme:Gmet_0890 smf protein; DNA protecting protein DprA complement(1781182..1782213) Kosmotoga olearia TBF 19.5.1 7967892 YP_002941347.1 CDS hslU NC_012785.1 1782217 1783611 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU complement(1782217..1783611) Kosmotoga olearia TBF 19.5.1 7967893 YP_002941348.1 CDS Kole_1655 NC_012785.1 1783611 1784156 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit complement(1783611..1784156) Kosmotoga olearia TBF 19.5.1 7967894 YP_002941349.1 CDS Kole_1656 NC_012785.1 1784173 1785090 R KEGG: pca:Pcar_2199 D-alanine--D-alanine ligase; TIGRFAM: D-alanine/D-alanine ligase; PFAM: D-alanine--D-alanine ligase domain protein; protein of unknown function DUF201; RimK domain protein ATP-grasp; D-alanine/D-alanine ligase complement(1784173..1785090) Kosmotoga olearia TBF 19.5.1 7967895 YP_002941350.1 CDS Kole_1657 NC_012785.1 1785083 1787308 R KEGG: nam:NAMH_0110 DNA topoisomerase I; TIGRFAM: DNA topoisomerase I; PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain protein; DNA topoisomerase type IA zn finger domain protein; SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain protein; DNA topoisomerase I complement(1785083..1787308) Kosmotoga olearia TBF 19.5.1 7967896 YP_002941351.1 CDS Kole_1658 NC_012785.1 1787318 1788370 R KEGG: sat:SYN_02192 HD-superfamily hydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; nucleic acid binding OB-fold tRNA/helicase-type; SMART: metal-dependent phosphohydrolase HD region; metal dependent phosphohydrolase complement(1787318..1788370) Kosmotoga olearia TBF 19.5.1 7967897 YP_002941352.1 CDS Kole_1659 NC_012785.1 1788375 1789493 R KEGG: baa:BA_2575 alanine racemase; TIGRFAM: alanine racemase; PFAM: alanine racemase domain protein; alanine racemase complement(1788375..1789493) Kosmotoga olearia TBF 19.5.1 7967898 YP_002941353.1 CDS Kole_1660 NC_012785.1 1789531 1789722 R TIGRFAM: ribosomal protein L28; PFAM: ribosomal protein L28; KEGG: gsu:GSU2234 50S ribosomal protein L28; ribosomal protein L28 complement(1789531..1789722) Kosmotoga olearia TBF 19.5.1 7967899 YP_002941354.1 CDS Kole_1661 NC_012785.1 1789848 1790504 D PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: pca:Pcar_2947 HAD superfamily hydrolase; Haloacid dehalogenase domain protein hydrolase 1789848..1790504 Kosmotoga olearia TBF 19.5.1 7968062 YP_002941355.1 CDS Kole_1662 NC_012785.1 1790590 1791558 D hypothetical protein 1790590..1791558 Kosmotoga olearia TBF 19.5.1 7968063 YP_002941356.1 CDS Kole_1663 NC_012785.1 1791687 1794269 D KEGG: bar:GBAA2728 pullulanase, TIGRFAM: pullulanase, type I; PFAM: pullanase-associated protein; glycoside hydrolase family 13 domain protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; pullulanase, type I 1791687..1794269 Kosmotoga olearia TBF 19.5.1 7968064 YP_002941357.1 CDS Kole_1664 NC_012785.1 1794301 1794768 D PFAM: molybdopterin binding domain; KEGG: dvm:DvMF_1339 molybdenum cofactor synthesis domain protein; molybdopterin binding domain protein 1794301..1794768 Kosmotoga olearia TBF 19.5.1 7968065 YP_002941358.1 CDS Kole_1665 NC_012785.1 1794770 1795387 D PFAM: deoxynucleoside kinase; KEGG: mxa:MXAN_2054 deoxynucleoside kinase family protein; deoxynucleoside kinase 1794770..1795387 Kosmotoga olearia TBF 19.5.1 7968066 YP_002941359.1 CDS Kole_1666 NC_012785.1 1795384 1796037 D PFAM: deoxynucleoside kinase; KEGG: mxa:MXAN_3331 deoxynucleoside kinase family protein; deoxynucleoside kinase 1795384..1796037 Kosmotoga olearia TBF 19.5.1 7968067 YP_002941360.1 CDS Kole_1667 NC_012785.1 1796286 1801250 D PFAM: Pyrrolo-quinoline quinone; SMART: Pyrrolo-quinoline quinone; KEGG: bsu:BSU39940 hypothetical protein; Pyrrolo-quinoline quinone 1796286..1801250 Kosmotoga olearia TBF 19.5.1 7968068 YP_002941361.1 CDS Kole_1668 NC_012785.1 1801371 1802708 D TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: pha:PSHAa2154 efflux pump; MATE efflux family protein 1801371..1802708 Kosmotoga olearia TBF 19.5.1 7968069 YP_002941362.1 CDS Kole_1669 NC_012785.1 1802764 1803864 R KEGG: pca:Pcar_2387 hypothetical protein; TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: Radical SAM domain protein; lysine 2,3-aminomutase YodO family protein complement(1802764..1803864) Kosmotoga olearia TBF 19.5.1 7968070 YP_002941363.1 CDS Kole_1670 NC_012785.1 1804158 1805342 R PFAM: Integrase catalytic region; KEGG: bja:bll1898 transposase; Integrase catalytic region complement(1804158..1805342) Kosmotoga olearia TBF 19.5.1 7968071 YP_002941364.1 CDS Kole_1671 NC_012785.1 1805707 1806486 D PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; ionotropic glutamate receptor; KEGG: aha:AHA_2800 amino acid ABC transporter, periplasmic amino acid-binding protein; extracellular solute-binding protein family 3 1805707..1806486 Kosmotoga olearia TBF 19.5.1 7968072 YP_002941365.1 CDS Kole_1672 NC_012785.1 1806502 1807236 D TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: gsu:GSU2650 amino acid ABC transporter, permease protein; polar amino acid ABC transporter, inner membrane subunit 1806502..1807236 Kosmotoga olearia TBF 19.5.1 7968073 YP_002941366.1 CDS Kole_1673 NC_012785.1 1807233 1807973 D PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ccv:CCV52592_0494 glutamate/aspartate ABC transporter, ATP-binding protein; ABC transporter 1807233..1807973 Kosmotoga olearia TBF 19.5.1 7968074 YP_002941367.1 CDS Kole_1674 NC_012785.1 1808056 1808685 D KEGG: sus:Acid_3412 hypothetical protein; hypothetical protein 1808056..1808685 Kosmotoga olearia TBF 19.5.1 7968075 YP_002941368.1 CDS Kole_1675 NC_012785.1 1808783 1809565 D KEGG: ilo:IL0572 hypothetical protein; hypothetical protein 1808783..1809565 Kosmotoga olearia TBF 19.5.1 7968076 YP_002941369.1 CDS Kole_1676 NC_012785.1 1809685 1810647 D PFAM: aldo/keto reductase; KEGG: hypothetical protein; aldo/keto reductase 1809685..1810647 Kosmotoga olearia TBF 19.5.1 7968077 YP_002941370.1 CDS Kole_1677 NC_012785.1 1810699 1811541 D KEGG: ade:Adeh_2788 NAD synthetase; TIGRFAM: NAD+ synthetase; PFAM: NAD synthase; NAD+ synthetase 1810699..1811541 Kosmotoga olearia TBF 19.5.1 7968078 YP_002941371.1 CDS Kole_1678 NC_012785.1 1811558 1811881 R hypothetical protein complement(1811558..1811881) Kosmotoga olearia TBF 19.5.1 7968079 YP_002941372.1 CDS Kole_1679 NC_012785.1 1811887 1812414 R hypothetical protein complement(1811887..1812414) Kosmotoga olearia TBF 19.5.1 7968080 YP_002941373.1 CDS Kole_1680 NC_012785.1 1812792 1813166 D TIGRFAM: CrcB protein; PFAM: Camphor resistance CrcB protein; KEGG: cjj:CJJ81176_0545 CrcB protein; CrcB protein 1812792..1813166 Kosmotoga olearia TBF 19.5.1 7968081 YP_002941374.1 CDS Kole_1681 NC_012785.1 1813163 1813489 D PFAM: protein of unknown function DUF190; KEGG: ppd:Ppro_0834 hypothetical protein; hypothetical protein 1813163..1813489 Kosmotoga olearia TBF 19.5.1 7968082 YP_002941375.1 CDS Kole_1682 NC_012785.1 1813557 1815407 D PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: baa:BA_2835 rotamase, PPIC-type PPIASE domain; PpiC-type peptidyl-prolyl cis-trans isomerase 1813557..1815407 Kosmotoga olearia TBF 19.5.1 7968083 YP_002941376.1 CDS Kole_1683 NC_012785.1 1815460 1816422 R hypothetical protein complement(1815460..1816422) Kosmotoga olearia TBF 19.5.1 7968084 YP_002941377.1 CDS Kole_1684 NC_012785.1 1816479 1817333 R hypothetical protein complement(1816479..1817333) Kosmotoga olearia TBF 19.5.1 7968085 YP_002941378.1 CDS Kole_1685 NC_012785.1 1817338 1818471 R KEGG: bsu:BSU27710 queuine tRNA-ribosyltransferase; TIGRFAM: queuine tRNA-ribosyltransferase; tRNA-guanine transglycosylase, various specificities; PFAM: Queuine/other tRNA-ribosyltransferase; queuine tRNA-ribosyltransferase complement(1817338..1818471) Kosmotoga olearia TBF 19.5.1 7968086 YP_002941379.1 CDS Kole_1686 NC_012785.1 1818464 1819093 R PFAM: Formiminotransferase-cyclodeaminase; KEGG: mch:Mchl_2134 formiminotransferase-cyclodeaminase; Formimidoyltetrahydrofolate cyclodeaminase complement(1818464..1819093) Kosmotoga olearia TBF 19.5.1 7968087 YP_002941380.1 CDS Kole_1687 NC_012785.1 1819113 1819850 R KEGG: dps:DP1973 deoxyribose-phosphate aldolase; TIGRFAM: deoxyribose-phosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; deoxyribose-phosphate aldolase complement(1819113..1819850) Kosmotoga olearia TBF 19.5.1 7968088 YP_002941381.1 CDS Kole_1688 NC_012785.1 1819861 1820409 R KEGG: dvm:DvMF_0761 metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; metal dependent phosphohydrolase complement(1819861..1820409) Kosmotoga olearia TBF 19.5.1 7968089 YP_002941382.1 CDS Kole_1690 NC_012785.1 1821088 1821609 R TIGRFAM: maf protein; PFAM: Maf family protein; KEGG: bar:GBAA4686 Maf-like protein; maf protein complement(1821088..1821609) Kosmotoga olearia TBF 19.5.1 7968091 YP_002941383.1 CDS Kole_1691 NC_012785.1 1821660 1822160 R PFAM: Heptaprenyl diphosphate synthase component I; KEGG: tmz:Tmz1t_0773 heptaprenyl diphosphate synthase component I; Heptaprenyl diphosphate synthase component I complement(1821660..1822160) Kosmotoga olearia TBF 19.5.1 7968092 YP_002941384.1 CDS Kole_1692 NC_012785.1 1822157 1822528 R PFAM: protein of unknown function DUF1312; KEGG: tmz:Tmz1t_0772 hypothetical protein; hypothetical protein complement(1822157..1822528) Kosmotoga olearia TBF 19.5.1 7968093 YP_002941385.1 CDS Kole_1693 NC_012785.1 1822525 1823565 R PFAM: ApbE family lipoprotein; KEGG: pca:Pcar_0035 hypothetical protein; ApbE family lipoprotein complement(1822525..1823565) Kosmotoga olearia TBF 19.5.1 7968094 YP_002941386.1 CDS Kole_1694 NC_012785.1 1823535 1824527 R PFAM: Radical SAM domain protein; KEGG: sfu:Sfum_0354 radical SAM domain protein; Radical SAM domain protein complement(1823535..1824527) Kosmotoga olearia TBF 19.5.1 7968095 YP_002941387.1 CDS Kole_1695 NC_012785.1 1824548 1825069 R PFAM: AMMECR1 domain protein; KEGG: dal:Dalk_3956 AMMECR1 domain protein; AMMECR1 domain protein complement(1824548..1825069) Kosmotoga olearia TBF 19.5.1 7968096 YP_002941388.1 CDS Kole_1696 NC_012785.1 1825074 1826096 R PFAM: phosphofructokinase; KEGG: mxa:MXAN_6373 6-phosphofructokinase I; 6-phosphofructokinase complement(1825074..1826096) Kosmotoga olearia TBF 19.5.1 7968097 YP_002941389.1 CDS Kole_1697 NC_012785.1 1826198 1828396 D KEGG: bsu:BSU33610 ribonuclease R; TIGRFAM: ribonuclease R; VacB and RNase II family 3'-5' exoribonuclease; PFAM: ribonuclease II; Ribonuclease B OB region domain; RNA binding S1 domain protein; SMART: RNA binding S1 domain protein; ribonuclease R 1826198..1828396 Kosmotoga olearia TBF 19.5.1 7968098 YP_002941390.1 CDS Kole_1698 NC_012785.1 1828539 1829606 D PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; SMART: Tetratricopeptide domain protein; KEGG: SLEI family protein; hypothetical protein 1828539..1829606 Kosmotoga olearia TBF 19.5.1 7968099 YP_002941391.1 CDS Kole_1699 NC_012785.1 1829606 1830361 D PFAM: peptidase A24A domain protein; peptidase A24A prepilin type IV; KEGG: dal:Dalk_1245 peptidase A24A domain protein; peptidase A24A domain protein 1829606..1830361 Kosmotoga olearia TBF 19.5.1 7968100 YP_002941392.1 CDS Kole_1700 NC_012785.1 1830379 1832049 R PFAM: helix-turn-helix domain protein; XRE family transcriptional regulator complement(1830379..1832049) Kosmotoga olearia TBF 19.5.1 7968101 YP_002941393.1 CDS Kole_1701 NC_012785.1 1832229 1832453 D hypothetical protein 1832229..1832453 Kosmotoga olearia TBF 19.5.1 7968102 YP_002941394.1 CDS Kole_1702 NC_012785.1 1832467 1832577 D hypothetical protein 1832467..1832577 Kosmotoga olearia TBF 19.5.1 7968103 YP_002941395.1 CDS eno NC_012785.1 1834723 1836009 R enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase complement(1834723..1836009) Kosmotoga olearia TBF 19.5.1 7968105 YP_002941396.1 CDS pyrH NC_012785.1 1836027 1836728 R Catalyzes the phosphorylation of UMP to UDP; uridylate kinase complement(1836027..1836728) Kosmotoga olearia TBF 19.5.1 7968106 YP_002941397.1 CDS Kole_1707 NC_012785.1 1836781 1837383 R TIGRFAM: translation elongation factor Ts; PFAM: Translation elongation factor EFTs/EF1B dimerisation; ubiquitin-associated- domain-containing protein; KEGG: dat:HRM2_17110 Tsf; translation elongation factor Ts complement(1836781..1837383) Kosmotoga olearia TBF 19.5.1 7968107 YP_002941398.1 CDS Kole_1708 NC_012785.1 1837456 1837938 R KEGG: bha:BH2589 lipopolysaccharide core biosynthesis; TIGRFAM: pantetheine-phosphate adenylyltransferase; cytidyltransferase-related domain protein; PFAM: cytidylyltransferase; pantetheine-phosphate adenylyltransferase complement(1837456..1837938) Kosmotoga olearia TBF 19.5.1 7968108 YP_002941399.1 CDS Kole_1709 NC_012785.1 1837935 1838414 R TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; KEGG: dvm:DvMF_2591 BadM/Rrf2 family transcriptional regulator; BadM/Rrf2 family transcriptional regulator complement(1837935..1838414) Kosmotoga olearia TBF 19.5.1 7968109 YP_002941400.1 CDS Kole_1710 NC_012785.1 1838418 1839335 R KEGG: gsu:GSU1132 cell division protein FtsY; TIGRFAM: signal recognition particle-docking protein FtsY; PFAM: GTP-binding signal recognition particle SRP54 G- domain; GTP-binding signal recognition particle SRP54 helical bundle; SMART: AAA ATPase; signal recognition particle-docking protein FtsY complement(1838418..1839335) Kosmotoga olearia TBF 19.5.1 7968110 YP_002941401.1 CDS Kole_1711 NC_012785.1 1839337 1841082 R catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase complement(1839337..1841082) Kosmotoga olearia TBF 19.5.1 7968111 YP_002941402.1 CDS Kole_1712 NC_012785.1 1841214 1842074 D catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 1841214..1842074 Kosmotoga olearia TBF 19.5.1 7968112 YP_002941403.1 CDS cysS NC_012785.1 1842260 1843636 R catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase complement(1842260..1843636) Kosmotoga olearia TBF 19.5.1 7968114 YP_002941404.1 CDS gltX NC_012785.1 1843630 1845081 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(1843630..1845081) Kosmotoga olearia TBF 19.5.1 7968115 YP_002941405.1 CDS Kole_1715 NC_012785.1 1845088 1845615 R PFAM: NUDIX hydrolase; KEGG: bha:BH1524 hypothetical protein; NUDIX hydrolase complement(1845088..1845615) Kosmotoga olearia TBF 19.5.1 7968116 YP_002941406.1 CDS Kole_1716 NC_012785.1 1845621 1846019 R TIGRFAM: cytidine deaminase; PFAM: CMP/dCMP deaminase zinc-binding; KEGG: similar to CG8360 CG8360-PA; cytidine deaminase complement(1845621..1846019) Kosmotoga olearia TBF 19.5.1 7968117 YP_002941407.1 CDS Kole_1717 NC_012785.1 1845967 1847346 R PFAM: protein of unknown function DUF21; CBS domain containing protein; transporter-associated region; SMART: CBS domain containing protein; KEGG: dal:Dalk_3618 protein of unknown function DUF21; hypothetical protein complement(1845967..1847346) Kosmotoga olearia TBF 19.5.1 7968118 YP_002941408.1 CDS Kole_1718 NC_012785.1 1847382 1847849 R PFAM: protein of unknown function DUF163; KEGG: geo:Geob_0611 protein of unknown function DUF163; hypothetical protein complement(1847382..1847849) Kosmotoga olearia TBF 19.5.1 7968119 YP_002941409.1 CDS Kole_1719 NC_012785.1 1847839 1849059 R KEGG: baa:BA_4193 ATZ_TRZ, Chlorohydrolase; TIGRFAM: imidazolonepropionase; PFAM: amidohydrolase; Amidohydrolase 3; imidazolonepropionase complement(1847839..1849059) Kosmotoga olearia TBF 19.5.1 7968120 YP_002941410.1 CDS Kole_1720 NC_012785.1 1849062 1849973 R KEGG: aba:Acid345_2130 formiminotransferase-like; TIGRFAM: glutamate formiminotransferase; PFAM: Formiminotransferase domain protein; Formiminotransferase domain protein; glutamate formiminotransferase complement(1849062..1849973) Kosmotoga olearia TBF 19.5.1 7968121 YP_002941411.1 CDS Kole_1721 NC_012785.1 1850026 1851087 R PFAM: cell cycle protein; KEGG: bpn:BPEN_316 rod shape-determining protein; cell cycle protein complement(1850026..1851087) Kosmotoga olearia TBF 19.5.1 7968122 YP_002941412.1 CDS Kole_1722 NC_012785.1 1851071 1851994 R PFAM: PP-loop domain protein; KEGG: dvm:DvMF_2330 PP-loop domain protein; PP-loop domain protein complement(1851071..1851994) Kosmotoga olearia TBF 19.5.1 7968123 YP_002941413.1 CDS Kole_1723 NC_012785.1 1852146 1852982 D KEGG: har:HEAR1318 hypothetical protein; hypothetical protein 1852146..1852982 Kosmotoga olearia TBF 19.5.1 7968124 YP_002941414.1 CDS panB NC_012785.1 1852960 1853763 D catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 1852960..1853763 Kosmotoga olearia TBF 19.5.1 7968125 YP_002941415.1 CDS Kole_1725 NC_012785.1 1853756 1854562 D PFAM: MscS Mechanosensitive ion channel; KEGG: ilo:IL2015 small-conductance mechanosensitive channel; MscS Mechanosensitive ion channel 1853756..1854562 Kosmotoga olearia TBF 19.5.1 7968126 YP_002941416.1 CDS Kole_1726 NC_012785.1 1854567 1855292 D TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; KEGG: bsu:BSU22440 transcriptional regulator and biotin acetyl-CoA-carboxylase synthetase; biotin/acetyl-CoA-carboxylase ligase 1854567..1855292 Kosmotoga olearia TBF 19.5.1 7968127 YP_002941417.1 CDS Kole_1727 NC_012785.1 1855282 1855506 R PFAM: RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; KEGG: bha:BH0073 hypothetical protein; RNA-binding S4 domain protein complement(1855282..1855506) Kosmotoga olearia TBF 19.5.1 7968128 YP_002941418.1 CDS Kole_1728 NC_012785.1 1855619 1856950 R hypothetical protein complement(1855619..1856950) Kosmotoga olearia TBF 19.5.1 7968129 YP_002941419.1 CDS Kole_1729 NC_012785.1 1857037 1857480 R TIGRFAM: SsrA-binding protein; PFAM: SmpB protein; KEGG: rec:RHECIAT_CH0001450 SsrA-binding (tmRNA-binding) protein; SsrA-binding protein complement(1857037..1857480) Kosmotoga olearia TBF 19.5.1 7968130 YP_002941420.1 CDS Kole_1730 NC_012785.1 1857493 1859496 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B complement(1857493..1859496) Kosmotoga olearia TBF 19.5.1 7968131 YP_002941421.1 CDS Kole_1731 NC_012785.1 1859501 1860073 R KEGG: bsu:BSU00530 peptidyl-tRNA hydrolase; TIGRFAM: peptidyl-tRNA hydrolase; PFAM: peptidyl-tRNA hydrolase; peptidyl-tRNA hydrolase complement(1859501..1860073) Kosmotoga olearia TBF 19.5.1 7968132 YP_002941422.1 CDS Kole_1732 NC_012785.1 1860074 1860721 R the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25/general stress protein Ctc complement(1860074..1860721) Kosmotoga olearia TBF 19.5.1 7968133 YP_002941423.1 CDS Kole_1733 NC_012785.1 1860735 1861685 R catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase complement(1860735..1861685) Kosmotoga olearia TBF 19.5.1 7968134 YP_002941424.1 CDS Kole_1734 NC_012785.1 1861688 1863028 R TIGRFAM: UDP-N-acetylglucosamine pyrophosphorylase; PFAM: Nucleotidyl transferase; transferase hexapeptide repeat containing protein; 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; KEGG: gur:Gura_0122 UDP-N-acetylglucosamine pyrophosphorylase; UDP-N-acetylglucosamine pyrophosphorylase complement(1861688..1863028) Kosmotoga olearia TBF 19.5.1 7968135 YP_002941425.1 CDS Kole_1735 NC_012785.1 1863087 1863674 R PFAM: RuvA domain protein; SMART: Helix-hairpin-helix DNA-binding class 1; KEGG: pat:Patl_2945 Holliday junction DNA helicase RuvA; RuvA domain protein complement(1863087..1863674) Kosmotoga olearia TBF 19.5.1 7968136 YP_002941426.1 CDS Kole_1736 NC_012785.1 1863658 1864989 R KEGG: sfu:Sfum_1671 FolC bifunctional protein; TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; FolC bifunctional protein complement(1863658..1864989) Kosmotoga olearia TBF 19.5.1 7968137 YP_002941427.1 CDS Kole_1737 NC_012785.1 1864986 1867589 R TIGRFAM: valyl-tRNA synthetase; KEGG: sat:SYN_02886 valyl-tRNA synthetase; valyl-tRNA synthetase complement(1864986..1867589) Kosmotoga olearia TBF 19.5.1 7968138 YP_002941428.1 CDS Kole_1738 NC_012785.1 1867717 1868568 R PFAM: protein of unknown function DUF1385; KEGG: geo:Geob_0684 protein of unknown function DUF1385; hypothetical protein complement(1867717..1868568) Kosmotoga olearia TBF 19.5.1 7968139 YP_002941429.1 CDS Kole_1739 NC_012785.1 1868806 1869093 R PFAM: Stage V sporulation protein S; KEGG: bsu:BSU16980 required for dehydratation of the spore core and assembly of the coat (stage V sporulation); Stage V sporulation protein S complement(1868806..1869093) Kosmotoga olearia TBF 19.5.1 7968140 YP_002941430.1 CDS Kole_1740 NC_012785.1 1869330 1870487 R PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: sfu:Sfum_1166 2-oxoglutarate ferredoxin oxidoreductase subunit alpha; 2-oxoglutarate ferredoxin oxidoreductase subunit alpha complement(1869330..1870487) Kosmotoga olearia TBF 19.5.1 7968141 YP_002941431.1 CDS Kole_1741 NC_012785.1 1870480 1870704 R PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dps:DP2322 2-ketoglutarate oxidoreductase subunit delta; 4Fe-4S ferredoxin iron-sulfur binding domain protein complement(1870480..1870704) Kosmotoga olearia TBF 19.5.1 7968142 YP_002941432.1 CDS Kole_1742 NC_012785.1 1870720 1871847 R KEGG: dat:HRM2_38660 OadB3; TIGRFAM: sodium ion-translocating decarboxylase, beta subunit; PFAM: Na+transporting methylmalonyl-CoA/oxaloacetate decarboxylase beta subunit; sodium ion-translocating decarboxylase, beta subunit complement(1870720..1871847) Kosmotoga olearia TBF 19.5.1 7968226 YP_002941433.1 CDS Kole_1743 NC_012785.1 1871908 1874556 R catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase complement(1871908..1874556) Kosmotoga olearia TBF 19.5.1 7968227 YP_002941434.1 CDS Kole_1744 NC_012785.1 1874878 1876275 D TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: bba:Bd0267 hypothetical protein; glutamine synthetase, type I 1874878..1876275 Kosmotoga olearia TBF 19.5.1 7968228 YP_002941435.1 CDS Kole_1745 NC_012785.1 1876334 1876762 R PFAM: peptidylprolyl isomerase FKBP-type; KEGG: gme:Gmet_3146 peptidylprolyl isomerase, FKBP-type; peptidylprolyl isomerase FKBP-type complement(1876334..1876762) Kosmotoga olearia TBF 19.5.1 7968229 YP_002941436.1 CDS Kole_1746 NC_012785.1 1876891 1877922 R PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: mxa:MXAN_0313 mandelate racemase/muconate lactonizing enzyme family protein; Mandelate racemase/muconate lactonizing protein complement(1876891..1877922) Kosmotoga olearia TBF 19.5.1 7968230 YP_002941437.1 CDS Kole_1747 NC_012785.1 1877954 1879306 R PFAM: transglutaminase domain protein; SMART: transglutaminase domain protein; KEGG: sml:Smlt0460 transglutaminase; transglutaminase domain protein complement(1877954..1879306) Kosmotoga olearia TBF 19.5.1 7968231 YP_002941438.1 CDS Kole_1748 NC_012785.1 1879940 1880725 D type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase 1879940..1880725 Kosmotoga olearia TBF 19.5.1 7968235 YP_002941439.1 CDS Kole_1749 NC_012785.1 1880703 1882055 D PFAM: Radical SAM domain protein; cobalamin B12-binding domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: sat:SYN_02176 Fe-S oxidoreductase; Radical SAM domain protein 1880703..1882055 Kosmotoga olearia TBF 19.5.1 7968236 YP_002941440.1 CDS Kole_1750 NC_012785.1 1882048 1882572 D KEGG: baa:BA_0663 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 1882048..1882572 Kosmotoga olearia TBF 19.5.1 7968237 YP_002941441.1 CDS Kole_1751 NC_012785.1 1882607 1883110 D hypothetical protein 1882607..1883110 Kosmotoga olearia TBF 19.5.1 7968238 YP_002941442.1 CDS Kole_1752 NC_012785.1 1883100 1884017 D KEGG: sat:SYN_01651 radical SAM superfamily protein; TIGRFAM: conserved hypothetical protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; hypothetical protein 1883100..1884017 Kosmotoga olearia TBF 19.5.1 7968239 YP_002941443.1 CDS Kole_1753 NC_012785.1 1884466 1886127 D PFAM: Radical SAM domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: dat:HRM2_33330 Fe-S oxidoreductase family protein; Radical SAM domain protein 1884466..1886127 Kosmotoga olearia TBF 19.5.1 7968241 YP_002941444.1 CDS Kole_1755 NC_012785.1 1886599 1886712 D hypothetical protein 1886599..1886712 Kosmotoga olearia TBF 19.5.1 7968243 YP_002941445.1 CDS Kole_1756 NC_012785.1 1887486 1887929 R PFAM: OsmC family protein; KEGG: shw:Sputw3181_1218 OsmC family protein; OsmC family protein complement(1887486..1887929) Kosmotoga olearia TBF 19.5.1 7968244 YP_002941446.1 CDS Kole_1757 NC_012785.1 1888073 1888885 R PFAM: aldo/keto reductase; KEGG: azc:AZC_2900 aldo/keto reductase; aldo/keto reductase complement(1888073..1888885) Kosmotoga olearia TBF 19.5.1 7968245 YP_002941447.1 CDS Kole_1758 NC_012785.1 1889027 1889524 D KEGG: bam:Bamb_0115 hypothetical protein; hypothetical protein 1889027..1889524 Kosmotoga olearia TBF 19.5.1 7968246 YP_002941448.1 CDS Kole_1759 NC_012785.1 1889682 1891577 D PFAM: polysaccharide biosynthesis protein CapD; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; short-chain dehydrogenase/reductase SDR; dTDP-4-dehydrorhamnose reductase; NAD-dependent epimerase/dehydratase; KEGG: ank:AnaeK_4411 polysaccharide biosynthesis protein CapD; polysaccharide biosynthesis protein CapD 1889682..1891577 Kosmotoga olearia TBF 19.5.1 7968247 YP_002941449.1 CDS Kole_1760 NC_012785.1 1891620 1892783 D PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: bja:blr3650 polysaccharide biosynthesis protein; DegT/DnrJ/EryC1/StrS aminotransferase 1891620..1892783 Kosmotoga olearia TBF 19.5.1 7968248 YP_002941450.1 CDS Kole_1761 NC_012785.1 1892789 1893688 D PFAM: glycosyl transferase family 4; KEGG: sfu:Sfum_3327 glycosyl transferase, family 4; glycosyl transferase family 4 1892789..1893688 Kosmotoga olearia TBF 19.5.1 7968249 YP_002941451.1 CDS Kole_1762 NC_012785.1 1893681 1894613 R PFAM: Mg2 transporter protein CorA family protein; KEGG: baa:BA_2550 CorA-like Mg2+ transporter protein; Mg2 transporter protein CorA family protein complement(1893681..1894613) Kosmotoga olearia TBF 19.5.1 7968250 YP_002941452.1 CDS Kole_1763 NC_012785.1 1894792 1895454 R TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like); HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: rlt:Rleg2_4737 haloacid dehalogenase, type II; HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like) complement(1894792..1895454) Kosmotoga olearia TBF 19.5.1 7968251 YP_002941453.1 CDS Kole_1764 NC_012785.1 1895615 1896844 D PFAM: protein of unknown function DUF201; KEGG: dvm:DvMF_0668 ATP-grasp protein-like protein; hypothetical protein 1895615..1896844 Kosmotoga olearia TBF 19.5.1 7968252 YP_002941454.1 CDS Kole_1765 NC_012785.1 1897053 1897775 D KEGG: gsu:GSU0049 hypothetical protein; hypothetical protein 1897053..1897775 Kosmotoga olearia TBF 19.5.1 7968253 YP_002941455.1 CDS Kole_1766 NC_012785.1 1897735 1898385 D hypothetical protein 1897735..1898385 Kosmotoga olearia TBF 19.5.1 7968254 YP_002941456.1 CDS Kole_1767 NC_012785.1 1898386 1898805 R PFAM: ribonuclease H; KEGG: nse:NSE_0667 ribonuclease HI; ribonuclease H complement(1898386..1898805) Kosmotoga olearia TBF 19.5.1 7968255 YP_002941457.1 CDS Kole_1768 NC_012785.1 1898829 1900076 R PFAM: MOFRL domain protein; KEGG: sfu:Sfum_3915 MOFRL domain protein; Hydroxypyruvate reductase complement(1898829..1900076) Kosmotoga olearia TBF 19.5.1 7968256 YP_002941458.1 CDS Kole_1769 NC_012785.1 1900092 1901435 R TIGRFAM: gluconate transporter; PFAM: Gluconate transporter; Citrate transporter; KEGG: slo:Shew_2533 gluconate transporter; gluconate transporter complement(1900092..1901435) Kosmotoga olearia TBF 19.5.1 7968257 YP_002941459.1 CDS Kole_1770 NC_012785.1 1901587 1902825 D TIGRFAM: competence/damage-inducible protein CinA; PFAM: CinA domain protein; molybdopterin binding domain; KEGG: baa:BA_4387 competence-damaged protein; competence/damage-inducible protein CinA 1901587..1902825 Kosmotoga olearia TBF 19.5.1 7968258 YP_002941460.1 CDS Kole_1771 NC_012785.1 1903157 1904422 D TIGRFAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); KEGG: bsu:BSU36760 UDP-N-acetylglucosamine 1-carboxyvinyltransferase; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1903157..1904422 Kosmotoga olearia TBF 19.5.1 7968259 YP_002941461.1 CDS Kole_1772 NC_012785.1 1904432 1905382 D PFAM: Radical SAM domain protein; KEGG: gbm:Gbem_1899 radical SAM domain protein; Radical SAM domain protein 1904432..1905382 Kosmotoga olearia TBF 19.5.1 7968260 YP_002941462.1 CDS Kole_1773 NC_012785.1 1905379 1905735 D hypothetical protein 1905379..1905735 Kosmotoga olearia TBF 19.5.1 7968261 YP_002941463.1 CDS Kole_1774 NC_012785.1 1905732 1905986 D hypothetical protein 1905732..1905986 Kosmotoga olearia TBF 19.5.1 7968262 YP_002941464.1 CDS Kole_1775 NC_012785.1 1905983 1906255 D KEGG: ott:OTT_0823 Na+/H+ antiporter subunit; hypothetical protein 1905983..1906255 Kosmotoga olearia TBF 19.5.1 7968263 YP_002941465.1 CDS Kole_1776 NC_012785.1 1906257 1906952 D KEGG: psa:PST_4209 probable NADH dehydrogenase; hypothetical protein 1906257..1906952 Kosmotoga olearia TBF 19.5.1 7968264 YP_002941466.1 CDS Kole_1777 NC_012785.1 1906949 1907644 D PFAM: Na+/H+ antiporter MnhB subunit-related protein; KEGG: mgm:Mmc1_2212 monovalent cation/H+ antiporter subunit B; Na+/H+ antiporter MnhB subunit-related protein 1906949..1907644 Kosmotoga olearia TBF 19.5.1 7968265 YP_002941467.1 CDS Kole_1778 NC_012785.1 1907641 1908003 D PFAM: NADH-ubiquinone oxidoreductase chain 4L; KEGG: dal:Dalk_4921 NADH-ubiquinone oxidoreductase chain 4L; NADH-ubiquinone oxidoreductase chain 4L 1907641..1908003 Kosmotoga olearia TBF 19.5.1 7968266 YP_002941468.1 CDS Kole_1779 NC_012785.1 1908000 1909433 D PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: wol:WD1107 monovalent cation/H+ antiporter subunit D; NADH/Ubiquinone/plastoquinone (complex I) 1908000..1909433 Kosmotoga olearia TBF 19.5.1 7968267 YP_002941469.1 CDS Kole_1780 NC_012785.1 1910021 1910872 R TIGRFAM: degV family protein; PFAM: DegV family protein; KEGG: baa:BA_2750 DUF194, uncharacterized protein, DegV family COG1307; degV family protein complement(1910021..1910872) Kosmotoga olearia TBF 19.5.1 7968268 YP_002941470.1 CDS Kole_1781 NC_012785.1 1911037 1912017 D PFAM: PhoH family protein; KEGG: afw:Anae109_2713 PhoH family protein; PhoH family protein 1911037..1912017 Kosmotoga olearia TBF 19.5.1 7968269 YP_002941471.1 CDS Kole_1782 NC_012785.1 1912007 1913425 D KEGG: pca:Pcar_1232 HD superfamily hydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; metal dependent phosphohydrolase 1912007..1913425 Kosmotoga olearia TBF 19.5.1 7968270 YP_002941472.1 CDS Kole_1783 NC_012785.1 1913406 1913843 D PFAM: protein of unknown function UPF0054; KEGG: dps:DP1605 pyridoxal phosphate biosynthetic protein; hypothetical protein 1913406..1913843 Kosmotoga olearia TBF 19.5.1 7968271 YP_002941473.1 CDS Kole_1784 NC_012785.1 1913875 1915116 D PFAM: conserved hypothetical protein; KEGG: gur:Gura_1789 hypothetical protein; hypothetical protein 1913875..1915116 Kosmotoga olearia TBF 19.5.1 7968272 YP_002941474.1 CDS Kole_1785 NC_012785.1 1915113 1915820 D PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; KEGG: glo:Glov_0872 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; 4-diphosphocytidyl-2C-methyl-D-erythritol synthase 1915113..1915820 Kosmotoga olearia TBF 19.5.1 7968273 YP_002941475.1 CDS Kole_1786 NC_012785.1 1916063 1916464 D PFAM: transposase IS3/IS911 family protein; KEGG: pst:PSPTO_5508 ISPsy8, transposase OrfA; transposase IS3/IS911 family protein 1916063..1916464 Kosmotoga olearia TBF 19.5.1 7968274 YP_002941476.1 CDS Kole_1787 NC_012785.1 1916500 1917399 D PFAM: Integrase catalytic region; KEGG: cja:CJA_1427 transposase; Integrase catalytic region 1916500..1917399 Kosmotoga olearia TBF 19.5.1 7968275 YP_002941477.1 CDS Kole_1788 NC_012785.1 1917664 1917990 D PFAM: DNA polymerase beta domain protein region; KEGG: gbm:Gbem_0754 DNA polymerase beta domain protein region; DNA polymerase beta domain protein region 1917664..1917990 Kosmotoga olearia TBF 19.5.1 7968276 YP_002941478.1 CDS Kole_1789 NC_012785.1 1917962 1918336 D TIGRFAM: nucleotidyltransferase substrate binding protein, HI0074 family; PFAM: Nucleotidyltransferase substrate binding protein HI0074; KEGG: nis:NIS_0139 nucleotidyltransferase, substrate-binding protein; nucleotidyltransferase substrate binding protein, HI0074 family 1917962..1918336 Kosmotoga olearia TBF 19.5.1 7968277 YP_002941479.1 CDS Kole_1790 NC_012785.1 1918828 1919079 D KEGG: sfu:Sfum_1845 hypothetical protein; hypothetical protein 1918828..1919079 Kosmotoga olearia TBF 19.5.1 7968278 YP_002941480.1 CDS Kole_1791 NC_012785.1 1919085 1919576 D TIGRFAM: PAS sensor protein; KEGG: pca:Pcar_0517 PAS domain-containing protein; PAS/PAC sensor protein 1919085..1919576 Kosmotoga olearia TBF 19.5.1 7968279 YP_002941481.1 CDS Kole_1792 NC_012785.1 1919582 1920745 D PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: pca:Pcar_0518 hypothetical protein; protein serine/threonine phosphatase 1919582..1920745 Kosmotoga olearia TBF 19.5.1 7968280 YP_002941482.1 CDS Kole_1793 NC_012785.1 1920757 1920990 D KEGG: sat:SYN_01647 NADH-quinone oxidoreductase chain E; NADH-quinone oxidoreductase chain E 1920757..1920990 Kosmotoga olearia TBF 19.5.1 7968281 YP_002941483.1 CDS Kole_1794 NC_012785.1 1920987 1922423 D PFAM: hydrogenase large subunit domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dde:Dde_0725 hydrogenase-like; Ferredoxin hydrogenase 1920987..1922423 Kosmotoga olearia TBF 19.5.1 7968282 YP_002941484.1 CDS Kole_1796 NC_012785.1 1923322 1924044 R PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: bha:BH3999 transposase (26); IstB domain protein ATP-binding protein complement(1923322..1924044) Kosmotoga olearia TBF 19.5.1 7968284 YP_002941485.1 CDS Kole_1797 NC_012785.1 1924041 1925516 R KEGG: bha:BH3998 transposase (25); transposase (25) complement(1924041..1925516) Kosmotoga olearia TBF 19.5.1 7968285 YP_002941486.1 CDS Kole_1798 NC_012785.1 1925741 1926172 D KEGG: mlo:mll5961 transposase; transposase 1925741..1926172 Kosmotoga olearia TBF 19.5.1 7968286 YP_002941487.1 CDS Kole_1799 NC_012785.1 1926247 1927326 D PFAM: transposase IS204/IS1001/IS1096/IS1165 family protein; KEGG: ecm:EcSMS35_2272 ISL3 family transposase; transposase IS204/IS1001/IS1096/IS1165 family protein 1926247..1927326 Kosmotoga olearia TBF 19.5.1 7968287 YP_002941488.1 CDS Kole_1800 NC_012785.1 1927693 1928808 D KEGG: mxa:MXAN_3747 hypothetical protein; hypothetical protein 1927693..1928808 Kosmotoga olearia TBF 19.5.1 7968288 YP_002941489.1 CDS Kole_1801 NC_012785.1 1929117 1929251 D hypothetical protein 1929117..1929251 Kosmotoga olearia TBF 19.5.1 7968289 YP_002941490.1 CDS Kole_1802 NC_012785.1 1929266 1929652 D hypothetical protein 1929266..1929652 Kosmotoga olearia TBF 19.5.1 7968290 YP_002941491.1 CDS Kole_1803 NC_012785.1 1929660 1930565 R PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: sbp:Sbal223_2906 metal dependent phosphohydrolase; metal dependent phosphohydrolase complement(1929660..1930565) Kosmotoga olearia TBF 19.5.1 7968291 YP_002941492.1 CDS Kole_1804 NC_012785.1 1930720 1931133 R hypothetical protein complement(1930720..1931133) Kosmotoga olearia TBF 19.5.1 7968292 YP_002941493.1 CDS Kole_1805 NC_012785.1 1931400 1931531 D hypothetical protein 1931400..1931531 Kosmotoga olearia TBF 19.5.1 7968293 YP_002941494.1 CDS Kole_1806 NC_012785.1 1931528 1931779 D hypothetical protein 1931528..1931779 Kosmotoga olearia TBF 19.5.1 7968294 YP_002941495.1 CDS Kole_1807 NC_012785.1 1931763 1932365 D PFAM: transposase IS4 family protein; KEGG: dol:Dole_3091 transposase IS4 family protein; transposase IS4 family protein 1931763..1932365 Kosmotoga olearia TBF 19.5.1 7968295 YP_002941496.1 CDS Kole_1808 NC_012785.1 1932484 1933119 D PFAM: NUDIX hydrolase; KEGG: baa:BA_2567 NUDIX, MutT-like domain; NUDIX hydrolase 1932484..1933119 Kosmotoga olearia TBF 19.5.1 7968296 YP_002941497.1 CDS Kole_1809 NC_012785.1 1933269 1934093 D PFAM: Abortive infection protein; KEGG: baa:BA_1544 hypothetical protein; Abortive infection protein 1933269..1934093 Kosmotoga olearia TBF 19.5.1 7968297 YP_002941498.1 CDS Kole_1810 NC_012785.1 1934576 1935643 D KEGG: dar:Daro_0659 hypothetical protein; hypothetical protein 1934576..1935643 Kosmotoga olearia TBF 19.5.1 7968298 YP_002941499.1 CDS Kole_1813 NC_012785.1 1937947 1939140 D KEGG: abu:Abu_1405 McrBC catalytic subunit McrC; McrBC 5-methylcytosine restriction system component-like protein 1937947..1939140 Kosmotoga olearia TBF 19.5.1 7968301 YP_002941500.1 CDS Kole_1814 NC_012785.1 1939208 1940140 R PFAM: GCN5-related N-acetyltransferase; KEGG: mxa:MXAN_1686 acetyltransferase, GNAT family; GCN5-related N-acetyltransferase complement(1939208..1940140) Kosmotoga olearia TBF 19.5.1 7968302 YP_002941501.1 CDS Kole_1815 NC_012785.1 1940206 1941000 R PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: aba:Acid345_1190 UbiE/COQ5 methyltransferase; Methyltransferase type 11 complement(1940206..1941000) Kosmotoga olearia TBF 19.5.1 7968303 YP_002941502.1 CDS Kole_1816 NC_012785.1 1941272 1942042 D PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: pau:PA14_08440 short chain alcohol dehydrogenase; short-chain dehydrogenase/reductase SDR 1941272..1942042 Kosmotoga olearia TBF 19.5.1 7968304 YP_002941503.1 CDS Kole_1817 NC_012785.1 1942045 1942503 D KEGG: atc:AGR_C_2728 hypothetical protein; hypothetical protein 1942045..1942503 Kosmotoga olearia TBF 19.5.1 7968305 YP_002941504.1 CDS Kole_1818 NC_012785.1 1942586 1943377 D PFAM: GCN5-related N-acetyltransferase; KEGG: predicted protein; GCN5-related N-acetyltransferase 1942586..1943377 Kosmotoga olearia TBF 19.5.1 7968306 YP_002941505.1 CDS Kole_1819 NC_012785.1 1943452 1944132 D PFAM: protein of unknown function DUF500; KEGG: gbm:Gbem_2146 protein of unknown function DUF500; hypothetical protein 1943452..1944132 Kosmotoga olearia TBF 19.5.1 7967738 YP_002941506.1 CDS Kole_1820 NC_012785.1 1945204 1946409 R KEGG: mmr:Mmar10_1918 peptidase M1, membrane alanine aminopeptidase; hypothetical protein complement(1945204..1946409) Kosmotoga olearia TBF 19.5.1 7967739 YP_002941507.1 CDS Kole_1821 NC_012785.1 1946613 1948568 D PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; WD40 domain protein beta Propeller; peptidase S15; Acetyl xylan esterase; KEGG: bsu:BSU32230 hypothetical protein; peptidase S9 prolyl oligopeptidase active site domain protein 1946613..1948568 Kosmotoga olearia TBF 19.5.1 7967740 YP_002941508.1 CDS Kole_1822 NC_012785.1 1948565 1949590 D KEGG: hypothetical protein; hypothetical protein 1948565..1949590 Kosmotoga olearia TBF 19.5.1 7967741 YP_002941509.1 CDS Kole_1823 NC_012785.1 1949794 1951080 R PFAM: sigma-54 factor interaction domain-containing protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: gbm:Gbem_3940 two component, sigma54 specific, transcriptional regulator, fis family; sigma54 specific transcriptional regulator complement(1949794..1951080) Kosmotoga olearia TBF 19.5.1 7967743 YP_002941510.1 CDS Kole_1824 NC_012785.1 1951402 1952586 R PFAM: Integrase catalytic region; KEGG: bja:bll1898 transposase; Integrase catalytic region complement(1951402..1952586) Kosmotoga olearia TBF 19.5.1 7967744 YP_002941511.1 CDS Kole_1825 NC_012785.1 1952772 1953956 R PFAM: Integrase catalytic region; KEGG: bja:bll1898 transposase; Integrase catalytic region complement(1952772..1953956) Kosmotoga olearia TBF 19.5.1 7967745 YP_002941512.1 CDS Kole_1826 NC_012785.1 1954320 1955264 D AS-AR; AsnRS2; similar to asparaginyl-tRNA synthetase but lacking the N-terminal anticodon-binding site; the enzyme from Pyrococcus converts aspartic acid into asparagine; asparagine synthetase A 1954320..1955264 Kosmotoga olearia TBF 19.5.1 7967746 YP_002941513.1 CDS Kole_1827 NC_012785.1 1955363 1956205 D PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; KEGG: dat:HRM2_08790 cytochrome-c3 hydrogenase, gamma subunit (electron transfer subunit); oxidoreductase FAD/NAD(P)-binding domain protein 1955363..1956205 Kosmotoga olearia TBF 19.5.1 7967747 YP_002941514.1 CDS Kole_1828 NC_012785.1 1956202 1957602 D TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sat:SYN_00606 glutamate synthase (NADPH); glutamate synthase (NADPH), homotetrameric 1956202..1957602 Kosmotoga olearia TBF 19.5.1 7967748 YP_002941515.1 CDS Kole_1829 NC_012785.1 1957922 1959214 D PFAM: transposase IS116/IS110/IS902 family protein; transposase IS111A/IS1328/IS1533; KEGG: bxe:Bxe_B2763 transposase IS110; transposase IS116/IS110/IS902 family protein 1957922..1959214 Kosmotoga olearia TBF 19.5.1 7967749 YP_002941516.1 CDS Kole_1830 NC_012785.1 1959242 1959487 D hypothetical protein 1959242..1959487 Kosmotoga olearia TBF 19.5.1 7967750 YP_002941517.1 CDS Kole_1831 NC_012785.1 1959451 1959558 R hypothetical protein complement(1959451..1959558) Kosmotoga olearia TBF 19.5.1 7967751 YP_002941518.1 CDS Kole_1832 NC_012785.1 1959555 1960430 R TIGRFAM: degV family protein; PFAM: DegV family protein; KEGG: baa:BA_0283 DUF194, uncharacterized protein, DegV family COG1307; degV family protein complement(1959555..1960430) Kosmotoga olearia TBF 19.5.1 7967752 YP_002941519.1 CDS Kole_1833 NC_012785.1 1960660 1962162 R PFAM: peptidase M32 carboxypeptidase Taq metallopeptidase; KEGG: bsu:BSU22080 hypothetical protein; Carboxypeptidase Taq complement(1960660..1962162) Kosmotoga olearia TBF 19.5.1 7967753 YP_002941520.1 CDS Kole_1834 NC_012785.1 1962348 1963229 R PFAM: inner-membrane translocator; KEGG: smd:Smed_3657 inner-membrane translocator; inner-membrane translocator complement(1962348..1963229) Kosmotoga olearia TBF 19.5.1 7967754 YP_002941521.1 CDS Kole_1835 NC_012785.1 1963226 1964263 R PFAM: inner-membrane translocator; KEGG: smd:Smed_4009 inner-membrane translocator; inner-membrane translocator complement(1963226..1964263) Kosmotoga olearia TBF 19.5.1 7967755 YP_002941522.1 CDS Kole_1836 NC_012785.1 1964260 1965798 R PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: scl:sce7755 sugar ABC transporter, ATP-binding protein; ABC transporter complement(1964260..1965798) Kosmotoga olearia TBF 19.5.1 7967756 YP_002941523.1 CDS Kole_1837 NC_012785.1 1965955 1970637 R KEGG: gbm:Gbem_0927 DNA-directed RNA polymerase, beta' subunit; TIGRFAM: DNA-directed RNA polymerase, beta' subunit; PFAM: RNA polymerase Rpb1 domain 1; RNA polymerase alpha subunit; RNA polymerase Rpb1 domain 5; RNA polymerase Rpb1 domain 3; RNA polymerase Rpb1 domain 4; SMART: RNA polymerase I subunit A domain protein; DNA-directed RNA polymerase, beta' subunit complement(1965955..1970637) Kosmotoga olearia TBF 19.5.1 7967757 YP_002941524.1 CDS rpoB NC_012785.1 1970662 1974183 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta complement(1970662..1974183) Kosmotoga olearia TBF 19.5.1 7967758 YP_002941525.1 CDS rplL NC_012785.1 1974291 1974677 R present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 complement(1974291..1974677) Kosmotoga olearia TBF 19.5.1 7967759 YP_002941526.1 CDS Kole_1840 NC_012785.1 1974699 1975238 R binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 complement(1974699..1975238) Kosmotoga olearia TBF 19.5.1 7967760 YP_002941527.1 CDS rplA NC_012785.1 1975414 1976109 R in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 complement(1975414..1976109) Kosmotoga olearia TBF 19.5.1 7967761 YP_002941528.1 CDS Kole_1842 NC_012785.1 1976122 1976547 R KEGG: dal:Dalk_1925 ribosomal protein L11; TIGRFAM: ribosomal protein L11; PFAM: ribosomal protein L11; SMART: ribosomal protein L11; 50S ribosomal protein L11 complement(1976122..1976547) Kosmotoga olearia TBF 19.5.1 7967762 YP_002941529.1 CDS Kole_1843 NC_012785.1 1976618 1977682 R KEGG: bha:BH0118 transcription antitermination protein NusG; TIGRFAM: transcription termination/antitermination factor NusG; PFAM: NGN domain protein; KOW domain protein; SMART: NGN domain protein; KOW domain protein; NusG antitermination factor complement(1976618..1977682) Kosmotoga olearia TBF 19.5.1 7967763 YP_002941530.1 CDS Kole_1844 NC_012785.1 1977709 1977915 R TIGRFAM: preprotein translocase, SecE subunit; PFAM: protein secE/sec61-gamma protein; KEGG: dal:Dalk_1927 preprotein translocase, SecE subunit; preprotein translocase, SecE subunit complement(1977709..1977915) Kosmotoga olearia TBF 19.5.1 7967764 YP_002941531.1 CDS Kole_1845 NC_012785.1 1977946 1978113 R TIGRFAM: ribosomal protein L33; PFAM: ribosomal protein L33; KEGG: mxa:MXAN_3069 ribosomal protein L33; ribosomal protein L33 complement(1977946..1978113) Kosmotoga olearia TBF 19.5.1 7967765 YP_002941532.1 CDS Kole_1846 NC_012785.1 1978418 1979629 R KEGG: bha:BH2510 flavoprotein; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; PFAM: DNA/pantothenate metabolism flavoprotein domain protein; flavoprotein; phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase complement(1978418..1979629) Kosmotoga olearia TBF 19.5.1 7967768 YP_002941533.1 CDS Kole_1847 NC_012785.1 1979626 1979865 R TIGRFAM: DNA-directed RNA polymerase, omega subunit; DNA-directed RNA polymerase, omega subunit complement(1979626..1979865) Kosmotoga olearia TBF 19.5.1 7967769 YP_002941534.1 CDS gmk NC_012785.1 1979849 1980481 R Essential for recycling GMP and indirectly, cGMP; guanylate kinase complement(1979849..1980481) Kosmotoga olearia TBF 19.5.1 7967770 YP_002941535.1 CDS Kole_1849 NC_012785.1 1980478 1980777 R PFAM: protein of unknown function DUF370; KEGG: dde:Dde_2720 hypothetical protein; hypothetical protein complement(1980478..1980777) Kosmotoga olearia TBF 19.5.1 7967771 YP_002941536.1 CDS Kole_1850 NC_012785.1 1980790 1981662 R PFAM: domain of unknown function DUF1732; YicC domain protein; KEGG: dal:Dalk_1930 YicC domain protein; hypothetical protein complement(1980790..1981662) Kosmotoga olearia TBF 19.5.1 7967772 YP_002941537.1 CDS Kole_1851 NC_012785.1 1981718 1982845 R PFAM: aminotransferase class V; KEGG: sfu:Sfum_2683 aminotransferase, class V; Cysteine desulfurase complement(1981718..1982845) Kosmotoga olearia TBF 19.5.1 7967773 YP_002941538.1 CDS Kole_1852 NC_012785.1 1982832 1984850 R KEGG: bha:BH0649 NAD-dependent DNA ligase LigA; TIGRFAM: DNA ligase, NAD-dependent; PFAM: NAD-dependent DNA ligase adenylation; BRCT domain protein; helix-hairpin-helix motif; zinc-finger NAD-dependent DNA ligase C4-type; NAD-dependent DNA ligase OB-fold; SMART: NAD-dependent DNA ligase ; BRCT domain protein; Helix-hairpin-helix DNA-binding class 1; DNA ligase, NAD-dependent complement(1982832..1984850) Kosmotoga olearia TBF 19.5.1 7967774 YP_002941539.1 CDS Kole_1853 NC_012785.1 1984847 1985197 R TIGRFAM: holo-acyl-carrier-protein synthase; PFAM: 4'-phosphopantetheinyl transferase; KEGG: bsu:BSU04620 4'-phosphopantetheinyl transferase; holo-ACP synthase complement(1984847..1985197) Kosmotoga olearia TBF 19.5.1 7967775 YP_002941540.1 CDS Kole_1854 NC_012785.1 1985200 1987518 R KEGG: bar:GBAA4794 recombination and DNA strand exchange inhibitor protein; TIGRFAM: MutS2 family protein; PFAM: Smr protein/MutS2; DNA mismatch repair protein MutS domain protein; SMART: DNA mismatch repair protein MutS domain protein; MutS III domain protein; Smr protein/MutS2; MutS2 family protein complement(1985200..1987518) Kosmotoga olearia TBF 19.5.1 7967776 YP_002941541.1 CDS Kole_1855 NC_012785.1 1987496 1987939 R PFAM: Positive regulator of sigma(E) RseC/MucC; KEGG: mgm:Mmc1_1772 positive regulator of sigma(E), RseC/MucC; positive regulator of sigma E, RseC/MucC complement(1987496..1987939) Kosmotoga olearia TBF 19.5.1 7967777 YP_002941542.1 CDS Kole_1856 NC_012785.1 1987950 1988453 R hypothetical protein complement(1987950..1988453) Kosmotoga olearia TBF 19.5.1 7967778 YP_002941543.1 CDS Kole_1857 NC_012785.1 1988527 1989213 D PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: bha:BH0372 two-component response regulator; two component transcriptional regulator, winged helix family 1988527..1989213 Kosmotoga olearia TBF 19.5.1 7967779 YP_002941544.1 CDS Kole_1858 NC_012785.1 1989191 1990471 D PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: baa:BA_2715 HATPase_c, histidine kinase-, DNA gyrase B-, phytochrome-like ATPase; histidine kinase 1989191..1990471 Kosmotoga olearia TBF 19.5.1 7967780 YP_002941545.1 CDS Kole_1859 NC_012785.1 1990464 1991297 R PFAM: protein of unknown function DUF52; KEGG: aba:Acid345_3359 protein of unknown function DUF52; hypothetical protein complement(1990464..1991297) Kosmotoga olearia TBF 19.5.1 7967781 YP_002941546.1 CDS Kole_1860 NC_012785.1 1991297 1999183 R PFAM: type II and III secretion system protein; KEGG: noc:Noc_0251 fimbrial assembly protein PilQ precursor; type II and III secretion system protein complement(1991297..1999183) Kosmotoga olearia TBF 19.5.1 7967782 YP_002941547.1 CDS Kole_1861 NC_012785.1 1999241 1999684 R hypothetical protein complement(1999241..1999684) Kosmotoga olearia TBF 19.5.1 7967783 YP_002941548.1 CDS Kole_1862 NC_012785.1 1999697 2000338 R hypothetical protein complement(1999697..2000338) Kosmotoga olearia TBF 19.5.1 7967784 YP_002941549.1 CDS Kole_1864 NC_012785.1 2000857 2001879 R hypothetical protein complement(2000857..2001879) Kosmotoga olearia TBF 19.5.1 7967786 YP_002941550.1 CDS Kole_1865 NC_012785.1 2001894 2002274 R hypothetical protein complement(2001894..2002274) Kosmotoga olearia TBF 19.5.1 7967787 YP_002941551.1 CDS Kole_1866 NC_012785.1 2002284 2003486 R PFAM: type II secretion system protein; KEGG: gsu:GSU1493 type IV pilus biogenesis protein PilC; type II secretion system protein complement(2002284..2003486) Kosmotoga olearia TBF 19.5.1 7967788 YP_002941552.1 CDS Kole_1867 NC_012785.1 2003488 2003958 R KEGG: maq:Maqu_0924 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; TIGRFAM: 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; PFAM: MECDP-synthase; 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase complement(2003488..2003958) Kosmotoga olearia TBF 19.5.1 7967789 YP_002941553.1 CDS Kole_1868 NC_012785.1 2003959 2005062 R KEGG: noc:Noc_0002 DNA-directed DNA polymerase; TIGRFAM: DNA polymerase III, beta subunit; PFAM: DNA polymerase III beta chain; SMART: DNA polymerase III beta chain; DNA polymerase III, beta subunit complement(2003959..2005062) Kosmotoga olearia TBF 19.5.1 7967790 YP_002941554.1 CDS Kole_1869 NC_012785.1 2005152 2005832 D PFAM: Endonuclease V; KEGG: sat:SYN_01952 endonuclease V; Deoxyribonuclease V 2005152..2005832 Kosmotoga olearia TBF 19.5.1 7967791 YP_002941555.1 CDS Kole_1870 NC_012785.1 2005817 2006761 R PFAM: ROK family protein; KEGG: rlt:Rleg2_5489 ROK family protein; ROK family protein complement(2005817..2006761) Kosmotoga olearia TBF 19.5.1 7967792 YP_002941556.1 CDS rho NC_012785.1 2006775 2008181 R An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho complement(2006775..2008181) Kosmotoga olearia TBF 19.5.1 7967793 YP_002941557.1 CDS Kole_1872 NC_012785.1 2008414 2009070 R similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; translaldolase complement(2008414..2009070) Kosmotoga olearia TBF 19.5.1 7967794 YP_002941558.1 CDS Kole_1873 NC_012785.1 2009127 2009576 R TIGRFAM: ribosomal protein L17; PFAM: ribosomal protein L17; KEGG: zmo:ZMO0542 50S ribosomal protein L17; ribosomal protein L17 complement(2009127..2009576) Kosmotoga olearia TBF 19.5.1 7967795 YP_002941559.1 CDS Kole_1874 NC_012785.1 2009600 2010640 R catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha complement(2009600..2010640) Kosmotoga olearia TBF 19.5.1 7967796 YP_002941560.1 CDS rpsD NC_012785.1 2010668 2011294 R primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 complement(2010668..2011294) Kosmotoga olearia TBF 19.5.1 7967797 YP_002941561.1 CDS Kole_1876 NC_012785.1 2011311 2011703 R PFAM: ribosomal protein S11; KEGG: bar:GBAA0136 30S ribosomal protein S11; 30S ribosomal protein S11 complement(2011311..2011703) Kosmotoga olearia TBF 19.5.1 7967798 YP_002941562.1 CDS rpsM NC_012785.1 2011729 2012094 R located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 complement(2011729..2012094) Kosmotoga olearia TBF 19.5.1 7967799 YP_002941563.1 CDS Kole_1878 NC_012785.1 2012109 2012225 R TIGRFAM: ribosomal protein L36; PFAM: ribosomal protein L36; KEGG: ribosomal protein L36 family protein ; K02919 large subunit ribosomal protein L36; ribosomal protein L36 complement(2012109..2012225) Kosmotoga olearia TBF 19.5.1 7967800 YP_002941564.1 CDS Kole_1879 NC_012785.1 2012228 2012467 R KEGG: geo:Geob_2784 translation initiation factor IF-1; TIGRFAM: translation initiation factor IF-1; PFAM: S1 IF1 family protein; SMART: RNA binding S1 domain protein; translation initiation factor IF-1 complement(2012228..2012467) Kosmotoga olearia TBF 19.5.1 7967801 YP_002941565.1 CDS Kole_1880 NC_012785.1 2012480 2013232 R TIGRFAM: methionine aminopeptidase, type I; PFAM: peptidase M24; KEGG: sfu:Sfum_1577 methionine aminopeptidase, type I; methionine aminopeptidase, type I complement(2012480..2013232) Kosmotoga olearia TBF 19.5.1 7967802 YP_002941566.1 CDS Kole_1881 NC_012785.1 2013234 2013881 R TIGRFAM: adenylate kinase; PFAM: adenylate kinase; adenylate kinase lid domain protein; KEGG: bha:BH0155 adenylate kinase; adenylate kinase complement(2013234..2013881) Kosmotoga olearia TBF 19.5.1 7967803 YP_002941567.1 CDS secY NC_012785.1 2013887 2015173 R forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY complement(2013887..2015173) Kosmotoga olearia TBF 19.5.1 7967804 YP_002941568.1 CDS Kole_1883 NC_012785.1 2015175 2015621 R TIGRFAM: ribosomal protein L15; PFAM: ribosomal protein L15; KEGG: baa:BA_0712 ribosomal protein L15 amino terminal region; 50S ribosomal protein L15 complement(2015175..2015621) Kosmotoga olearia TBF 19.5.1 7967805 YP_002941569.1 CDS Kole_1884 NC_012785.1 2015636 2015824 R TIGRFAM: ribosomal protein L30; PFAM: ribosomal protein L30; KEGG: bha:BH0152 50S ribosomal protein L30; ribosomal protein L30 complement(2015636..2015824) Kosmotoga olearia TBF 19.5.1 7967806 YP_002941570.1 CDS rpsE NC_012785.1 2015809 2016372 R located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 complement(2015809..2016372) Kosmotoga olearia TBF 19.5.1 7967807 YP_002941571.1 CDS Kole_1886 NC_012785.1 2016386 2016754 R TIGRFAM: ribosomal protein L18; PFAM: ribosomal protein L18P/L5E; KEGG: sus:Acid_5102 50S ribosomal protein L18P; 50S ribosomal protein L18 complement(2016386..2016754) Kosmotoga olearia TBF 19.5.1 7967808 YP_002941572.1 CDS rplF NC_012785.1 2016778 2017332 R ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 complement(2016778..2017332) Kosmotoga olearia TBF 19.5.1 7967809 YP_002941573.1 CDS rpsH NC_012785.1 2017347 2017751 R binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 complement(2017347..2017751) Kosmotoga olearia TBF 19.5.1 7967810 YP_002941574.1 CDS Kole_1889 NC_012785.1 2017765 2017950 R PFAM: ribosomal protein S14; KEGG: nis:NIS_0236 30S ribosomal protein S14; ribosomal protein S14 complement(2017765..2017950) Kosmotoga olearia TBF 19.5.1 7967811 YP_002941575.1 CDS rplE NC_012785.1 2017968 2018519 R part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 complement(2017968..2018519) Kosmotoga olearia TBF 19.5.1 7967812 YP_002941576.1 CDS Kole_1891 NC_012785.1 2018540 2018863 R KEGG: sfu:Sfum_1566 ribosomal protein L24; TIGRFAM: ribosomal protein L24; PFAM: KOW domain protein; SMART: KOW domain protein; ribosomal protein L24 complement(2018540..2018863) Kosmotoga olearia TBF 19.5.1 7967813 YP_002941577.1 CDS Kole_1892 NC_012785.1 2018878 2019246 R TIGRFAM: ribosomal protein L14; PFAM: ribosomal protein L14b/L23e; KEGG: dal:Dalk_1905 ribosomal protein L14; 50S ribosomal protein L14 complement(2018878..2019246) Kosmotoga olearia TBF 19.5.1 7967814 YP_002941578.1 CDS Kole_1893 NC_012785.1 2019243 2019548 R PFAM: ribosomal protein S17; KEGG: afr:AFE_0336 ribosomal protein S17; 30S ribosomal protein S17 complement(2019243..2019548) Kosmotoga olearia TBF 19.5.1 7967815 YP_002941579.1 CDS Kole_1894 NC_012785.1 2019554 2019754 R TIGRFAM: ribosomal protein L29; PFAM: ribosomal protein L29; KEGG: bha:BH0142 50S ribosomal protein L29; ribosomal protein L29 complement(2019554..2019754) Kosmotoga olearia TBF 19.5.1 7967816 YP_002941580.1 CDS rplP NC_012785.1 2019754 2020179 R located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 complement(2019754..2020179) Kosmotoga olearia TBF 19.5.1 7967817 YP_002941581.1 CDS Kole_1896 NC_012785.1 2020211 2020858 R KEGG: lip:LI0966 30S ribosomal protein S3; TIGRFAM: ribosomal protein S3; PFAM: ribosomal protein S3- domain protein; KH type 2 domain protein; Ribosomal protein S3 domain; SMART: KH domain protein; 30S ribosomal protein S3 complement(2020211..2020858) Kosmotoga olearia TBF 19.5.1 7967818 YP_002941582.1 CDS rplV NC_012785.1 2020869 2021330 R binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 complement(2020869..2021330) Kosmotoga olearia TBF 19.5.1 7968388 YP_002941583.1 CDS rpsS NC_012785.1 2021345 2021629 R protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 complement(2021345..2021629) Kosmotoga olearia TBF 19.5.1 7968389 YP_002941584.1 CDS rplB NC_012785.1 2021646 2022473 R one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 complement(2021646..2022473) Kosmotoga olearia TBF 19.5.1 7968390 YP_002941585.1 CDS Kole_1900 NC_012785.1 2022490 2022792 R PFAM: Ribosomal protein L25/L23; KEGG: dat:HRM2_36240 RplW; Ribosomal protein L25/L23 complement(2022490..2022792) Kosmotoga olearia TBF 19.5.1 7968391 YP_002941586.1 CDS rplD NC_012785.1 2022792 2023472 R L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 complement(2022792..2023472) Kosmotoga olearia TBF 19.5.1 7968392 YP_002941587.1 CDS Kole_1902 NC_012785.1 2023496 2024137 R PFAM: ribosomal protein L3; KEGG: gsu:GSU2857 50S ribosomal protein L3; 50S ribosomal protein L3 complement(2023496..2024137) Kosmotoga olearia TBF 19.5.1 7968393 YP_002941588.1 CDS Kole_1903 NC_012785.1 2024161 2024469 R TIGRFAM: ribosomal protein S10; PFAM: ribosomal protein S10; KEGG: bar:GBAA0109 30S ribosomal protein S10; ribosomal protein S10 complement(2024161..2024469) Kosmotoga olearia TBF 19.5.1 7968394 YP_002941589.1 CDS Kole_1904 NC_012785.1 2024529 2025728 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(2024529..2025728) Kosmotoga olearia TBF 19.5.1 7968395 YP_002941590.1 CDS Kole_1905 NC_012785.1 2025761 2027830 R EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G complement(2025761..2027830) Kosmotoga olearia TBF 19.5.1 7968396 YP_002941591.1 CDS Kole_1906 NC_012785.1 2027856 2028323 R TIGRFAM: ribosomal protein S7; PFAM: ribosomal protein S7; KEGG: nam:NAMH_0183 ribosomal protein S7; 30S ribosomal protein S7 complement(2027856..2028323) Kosmotoga olearia TBF 19.5.1 7968397 YP_002941592.1 CDS Kole_1907 NC_012785.1 2028339 2028713 R TIGRFAM: ribosomal protein S12; PFAM: ribosomal protein S12/S23; KEGG: lip:LI0942 30S ribosomal protein S12; 30S ribosomal protein S12 complement(2028339..2028713) Kosmotoga olearia TBF 19.5.1 7968398 YP_002941593.1 CDS Kole_1908 NC_012785.1 2028893 2029828 R PFAM: DNA polymerase III delta; KEGG: cff:CFF8240_1130 DNA polymerase III subunit delta; DNA polymerase III delta complement(2028893..2029828) Kosmotoga olearia TBF 19.5.1 7968399 YP_002941594.1 CDS Kole_1909 NC_012785.1 2029832 2031577 R PFAM: penicillin-binding protein transpeptidase; PASTA domain containing protein; KEGG: sat:SYN_01739 division specific D,D-transpeptidase / cell division protein; Peptidoglycan glycosyltransferase complement(2029832..2031577) Kosmotoga olearia TBF 19.5.1 7968400 YP_002941595.1 CDS Kole_1910 NC_012785.1 2031696 2031986 R hypothetical protein complement(2031696..2031986) Kosmotoga olearia TBF 19.5.1 7968401 YP_002941596.1 CDS mraW NC_012785.1 2032002 2032898 R TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase; KEGG: gsu:GSU3077 S-adenosyl-methyltransferase MraW; S-adenosyl-methyltransferase MraW complement(2032002..2032898) Kosmotoga olearia TBF 19.5.1 7968402 YP_002941597.1 CDS prfB NC_012785.1 2032973 2034085 R recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 complement(2032973..2034085) Kosmotoga olearia TBF 19.5.1 7968403 YP_002941598.1 CDS Kole_1913 NC_012785.1 2034105 2036567 R functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA complement(2034105..2036567) Kosmotoga olearia TBF 19.5.1 7968404 YP_002941599.1 CDS Kole_1914 NC_012785.1 2036576 2038027 R hypothetical protein complement(2036576..2038027) Kosmotoga olearia TBF 19.5.1 7968405 YP_002941600.1 CDS Kole_1915 NC_012785.1 2038040 2038846 R KEGG: azc:AZC_3108 hemolysin A; TIGRFAM: hemolysin A; PFAM: RNA-binding S4 domain protein; ribosomal RNA methyltransferase RrmJ/FtsJ; SMART: RNA-binding S4 domain protein; hemolysin A complement(2038040..2038846) Kosmotoga olearia TBF 19.5.1 7968406 YP_002941601.1 CDS Kole_1916 NC_012785.1 2038830 2039582 R mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase ACD complement(2038830..2039582) Kosmotoga olearia TBF 19.5.1 7968407 YP_002941602.1 CDS Kole_1917 NC_012785.1 2039592 2040194 R hypothetical protein complement(2039592..2040194) Kosmotoga olearia TBF 19.5.1 7968408 YP_002941603.1 CDS Kole_1918 NC_012785.1 2040191 2041840 R PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; KEGG: bsu:BSU09310 hypothetical protein; Glucose-1,6-bisphosphate synthase complement(2040191..2041840) Kosmotoga olearia TBF 19.5.1 7968409 YP_002941604.1 CDS Kole_1919 NC_012785.1 2041845 2042192 R PFAM: protein of unknown function UPF0102; KEGG: dal:Dalk_4642 protein of unknown function UPF0102; hypothetical protein complement(2041845..2042192) Kosmotoga olearia TBF 19.5.1 7968410 YP_002941605.1 CDS Kole_1920 NC_012785.1 2042192 2042482 R TIGRFAM: glutamyl-tRNA(Gln) amidotransferase, C subunit; PFAM: Glu-tRNAGln amidotransferase C subunit; KEGG: cla:Cla_0485 glu-tRNAGln amidotransferase, subunit C; glutamyl-tRNA(Gln) amidotransferase, C subunit complement(2042192..2042482) Kosmotoga olearia TBF 19.5.1 7968411 YP_002941606.1 CDS Kole_1921 NC_012785.1 2042485 2043495 R KEGG: aba:Acid345_0343 galactose-1-phosphate uridylyltransferase; TIGRFAM: galactose-1-phosphate uridylyltransferase; PFAM: galactose-1-phosphate uridyl transferase domain protein; galactose-1-phosphate uridylyltransferase complement(2042485..2043495) Kosmotoga olearia TBF 19.5.1 7968412 YP_002941607.1 CDS Kole_1922 NC_012785.1 2043488 2044915 R TIGRFAM: glycogen/starch synthase, ADP-glucose type; PFAM: Starch synthase catalytic domain protein; glycosyl transferase group 1; KEGG: geo:Geob_1010 glycogen/starch synthase, ADP-glucose type; glycogen/starch synthase, ADP-glucose type complement(2043488..2044915) Kosmotoga olearia TBF 19.5.1 7968413 YP_002941608.1 CDS Kole_1923 NC_012785.1 2044915 2045544 R PFAM: beta-lactamase domain protein; KEGG: mes:Meso_2405 beta-lactamase-like; beta-lactamase domain protein complement(2044915..2045544) Kosmotoga olearia TBF 19.5.1 7968414 YP_002941609.1 CDS Kole_1924 NC_012785.1 2045545 2046333 R PFAM: Bacitracin resistance protein BacA; KEGG: bha:BH0464 undecaprenyl pyrophosphate phosphatase; Bacitracin resistance protein BacA complement(2045545..2046333) Kosmotoga olearia TBF 19.5.1 7968415 YP_002941610.1 CDS Kole_1925 NC_012785.1 2046326 2046937 R PFAM: CBS domain containing protein; amino acid-binding ACT domain protein; KEGG: bar:GBAA4917 acetoin utilization protein AcuB; CBS domain containing protein complement(2046326..2046937) Kosmotoga olearia TBF 19.5.1 7968416 YP_002941611.1 CDS Kole_1926 NC_012785.1 2047029 2048159 D KEGG: nam:NAMH_1022 hydrolase; hydrolase of HD superfamily-like protein 2047029..2048159 Kosmotoga olearia TBF 19.5.1 7968417 YP_002941612.1 CDS Kole_1927 NC_012785.1 2048177 2049340 R PFAM: aminotransferase class I and II; KEGG: nam:NAMH_0822 aspartate aminotransferase; aminotransferase class I and II complement(2048177..2049340) Kosmotoga olearia TBF 19.5.1 7968418 YP_002941613.1 CDS Kole_1928 NC_012785.1 2049364 2049996 R hypothetical protein complement(2049364..2049996) Kosmotoga olearia TBF 19.5.1 7968419 YP_002941614.1 CDS Kole_1929 NC_012785.1 2050017 2050211 R hypothetical protein complement(2050017..2050211) Kosmotoga olearia TBF 19.5.1 7968420 YP_002941615.1 CDS Kole_1930 NC_012785.1 2050215 2050910 R PFAM: 2-phosphosulfolactate phosphatase; KEGG: abo:ABO_2222 phosphoric monoester hydrolase; 2-phosphosulfolactate phosphatase complement(2050215..2050910) Kosmotoga olearia TBF 19.5.1 7968421 YP_002941616.1 CDS Kole_1931 NC_012785.1 2050912 2051553 R PFAM: Phosphoglycerate mutase; KEGG: pmr:PMI3716 probable phosphoglycerate mutase; Phosphoglycerate mutase complement(2050912..2051553) Kosmotoga olearia TBF 19.5.1 7968422 YP_002941617.1 CDS Kole_1932 NC_012785.1 2051550 2054294 R PFAM: DNA polymerase III alpha subunit; KEGG: sus:Acid_0012 DNA polymerase III, alpha subunit; DNA-directed DNA polymerase complement(2051550..2054294) Kosmotoga olearia TBF 19.5.1 7968423 YP_002941618.1 CDS Kole_1933 NC_012785.1 2054291 2055226 R KEGG: bha:BH2542 hypothetical protein; TIGRFAM: pseudouridine synthase, RluA family; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; pseudouridine synthase, RluA family complement(2054291..2055226) Kosmotoga olearia TBF 19.5.1 7968424 YP_002941619.1 CDS Kole_1934 NC_012785.1 2055195 2055665 R TIGRFAM: lipoprotein signal peptidase; PFAM: peptidase A8 signal peptidase II; KEGG: oan:Oant_0161 lipoprotein signal peptidase; lipoprotein signal peptidase complement(2055195..2055665) Kosmotoga olearia TBF 19.5.1 7968425 YP_002941620.1 CDS Kole_1935 NC_012785.1 2055729 2056487 R PFAM: protein of unknown function DUF28; KEGG: gme:Gmet_0743 hypothetical protein; hypothetical protein complement(2055729..2056487) Kosmotoga olearia TBF 19.5.1 7968426 YP_002941621.1 CDS Kole_1936 NC_012785.1 2056471 2057142 R KEGG: ppd:Ppro_0351 radical SAM domain-containing protein; hypothetical protein complement(2056471..2057142) Kosmotoga olearia TBF 19.5.1 7968427 YP_002941622.1 CDS Kole_1937 NC_012785.1 2057249 2057716 D TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase; KEGG: dal:Dalk_3260 phosphodiesterase, MJ0936 family; phosphodiesterase, MJ0936 family 2057249..2057716 Kosmotoga olearia TBF 19.5.1 7968428 YP_002941623.1 CDS Kole_1938 NC_012785.1 2057798 2059117 D TIGRFAM: trigger factor; PFAM: trigger factor domain protein; trigger factor domain; KEGG: sfu:Sfum_0101 trigger factor; trigger factor 2057798..2059117 Kosmotoga olearia TBF 19.5.1 7968429 YP_002941624.1 CDS Kole_1939 NC_012785.1 2059178 2060059 D TIGRFAM: prolipoprotein diacylglyceryl transferase; PFAM: prolipoprotein diacylglyceryl transferase; KEGG: bha:BH3589 prolipoprotein diacylglyceryl transferase; prolipoprotein diacylglyceryl transferase 2059178..2060059 Kosmotoga olearia TBF 19.5.1 7968430 YP_002941625.1 CDS Kole_1940 NC_012785.1 2060007 2060600 R TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; PFAM: Ham1 family protein; KEGG: ftf:FTF1560 HAM1 protein; non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family complement(2060007..2060600) Kosmotoga olearia TBF 19.5.1 7968431 YP_002941626.1 CDS Kole_1941 NC_012785.1 2060597 2061244 R KEGG: bha:BH2502 ribulose-phosphate 3-epimerase; TIGRFAM: ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; ribulose-phosphate 3-epimerase complement(2060597..2061244) Kosmotoga olearia TBF 19.5.1 7968432 YP_002941627.1 CDS Kole_1942 NC_012785.1 2061245 2062156 R TIGRFAM: ribosome small subunit-dependent GTPase A; PFAM: GTPase EngC; KEGG: bha:BH2503 ribosome-associated GTPase; ribosome small subunit-dependent GTPase A complement(2061245..2062156) Kosmotoga olearia TBF 19.5.1 7968433 YP_002941628.1 CDS Kole_1943 NC_012785.1 2062153 2063184 R 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N complement(2062153..2063184) Kosmotoga olearia TBF 19.5.1 7968434 YP_002941629.1 CDS Kole_1944 NC_012785.1 2063189 2064199 R PFAM: NusB/RsmB/TIM44; KEGG: bsu:BSU15740 hypothetical protein; NusB/RsmB/TIM44 complement(2063189..2064199) Kosmotoga olearia TBF 19.5.1 7968435 YP_002941630.1 CDS Kole_1945 NC_012785.1 2064199 2064885 R PFAM: peptidase membrane zinc metallopeptidase KEGG: bsu:BSU31310 hypothetical protein; peptidase membrane zinc metallopeptidase complement(2064199..2064885) Kosmotoga olearia TBF 19.5.1 7968436 YP_002941631.1 CDS Kole_1946 NC_012785.1 2065032 2065391 D PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: sus:Acid_1041 6-pyruvoyl tetrahydropterin synthase; 6-pyruvoyl tetrahydropterin synthase 2065032..2065391 Kosmotoga olearia TBF 19.5.1 7968437 YP_002941632.1 CDS Kole_1947 NC_012785.1 2065399 2066184 D PFAM: cobalt transport protein; KEGG: baa:BA_0724 cobalt transport protein; cobalt transport protein 2065399..2066184 Kosmotoga olearia TBF 19.5.1 7968438 YP_002941633.1 CDS Kole_1948 NC_012785.1 2066187 2067464 R PFAM: HEAT domain containing protein; KEGG: hypothetical protein; HEAT domain containing protein complement(2066187..2067464) Kosmotoga olearia TBF 19.5.1 7968439 YP_002941634.1 CDS Kole_1949 NC_012785.1 2067471 2067875 R hypothetical protein complement(2067471..2067875) Kosmotoga olearia TBF 19.5.1 7968440 YP_002941635.1 CDS gltX NC_012785.1 2067892 2069319 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(2067892..2069319) Kosmotoga olearia TBF 19.5.1 7968441 YP_002941636.1 CDS Kole_1951 NC_012785.1 2069332 2069832 R KEGG: scl:sce7148 hypothetical protein; hypothetical protein complement(2069332..2069832) Kosmotoga olearia TBF 19.5.1 7968442 YP_002941637.1 CDS Kole_1952 NC_012785.1 2069829 2070557 R PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: dvm:DvMF_0428 ABC transporter related; ABC transporter complement(2069829..2070557) Kosmotoga olearia TBF 19.5.1 7968443 YP_002941638.1 CDS Kole_1953 NC_012785.1 2070554 2071051 R PFAM: outer membrane chaperone Skp (OmpH); KEGG: lpc:LPC_2838 outer membrane protein OmpH; outer membrane chaperone Skp (OmpH) complement(2070554..2071051) Kosmotoga olearia TBF 19.5.1 7968444 YP_002941639.1 CDS Kole_1954 NC_012785.1 2071082 2071528 R TIGRFAM: D-tyrosyl-tRNA(Tyr) deacylase; PFAM: D-tyrosyl-tRNA(Tyr) deacylase; KEGG: gur:Gura_0610 D-tyrosyl-tRNA deacylase; D-tyrosyl-tRNA(Tyr) deacylase complement(2071082..2071528) Kosmotoga olearia TBF 19.5.1 7968445 YP_002941640.1 CDS Kole_1955 NC_012785.1 2071525 2073705 R KEGG: bar:GBAA4637 GTP pyrophosphokinase; TIGRFAM: RelA/SpoT family protein; PFAM: RelA/SpoT domain protein; TGS domain protein; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; (p)ppGpp synthetase I, SpoT/RelA complement(2071525..2073705) Kosmotoga olearia TBF 19.5.1 7968446 YP_002941641.1 CDS Kole_1956 NC_012785.1 2073777 2074511 R PFAM: protein of unknown function DUF81; KEGG: pca:Pcar_3013 hypothetical protein; hypothetical protein complement(2073777..2074511) Kosmotoga olearia TBF 19.5.1 7968447 YP_002941642.1 CDS Kole_1957 NC_012785.1 2074735 2075760 D hypothetical protein 2074735..2075760 Kosmotoga olearia TBF 19.5.1 7968448 YP_002941643.1 CDS Kole_1958 NC_012785.1 2076003 2076920 D PFAM: integrase family protein; integrase domain protein SAM domain protein; KEGG: ade:Adeh_1687 tyrosine recombinase XerD subunit; integrase family protein 2076003..2076920 Kosmotoga olearia TBF 19.5.1 7968449 YP_002941644.1 CDS Kole_1959 NC_012785.1 2077128 2077880 R hypothetical protein complement(2077128..2077880) Kosmotoga olearia TBF 19.5.1 7968450 YP_002941645.1 CDS Kole_1960 NC_012785.1 2077858 2078649 R PFAM: Patatin; KEGG: cti:RALTA_A1947 lipoprotein, esterase of the alpha-beta hydrolase superfamily, patatin-like phospholipase domain; Patatin complement(2077858..2078649) Kosmotoga olearia TBF 19.5.1 7968451 YP_002941646.1 CDS Kole_1961 NC_012785.1 2078847 2079308 R PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: acb:A1S_3468 lipoprotein; XRE family transcriptional regulator complement(2078847..2079308) Kosmotoga olearia TBF 19.5.1 7968452 YP_002941647.1 CDS Kole_1962 NC_012785.1 2079305 2079703 R hypothetical protein complement(2079305..2079703) Kosmotoga olearia TBF 19.5.1 7968453 YP_002941648.1 CDS Kole_1963 NC_012785.1 2079786 2080688 R KEGG: abb:ABBFA_003435 hypothetical protein; hypothetical protein complement(2079786..2080688) Kosmotoga olearia TBF 19.5.1 7968454 YP_002941649.1 CDS Kole_1964 NC_012785.1 2080727 2081464 R hypothetical protein complement(2080727..2081464) Kosmotoga olearia TBF 19.5.1 7968455 YP_002941650.1 CDS Kole_1965 NC_012785.1 2081469 2082008 R hypothetical protein complement(2081469..2082008) Kosmotoga olearia TBF 19.5.1 7968456 YP_002941651.1 CDS Kole_1966 NC_012785.1 2082508 2083002 R KEGG: vfm:VFMJ11_A0645 hypothetical protein; hypothetical protein complement(2082508..2083002) Kosmotoga olearia TBF 19.5.1 7968457 YP_002941652.1 CDS Kole_1967 NC_012785.1 2083169 2083825 R KEGG: vvy:VV1934 hypothetical protein; hypothetical protein complement(2083169..2083825) Kosmotoga olearia TBF 19.5.1 7968458 YP_002941653.1 CDS Kole_1968 NC_012785.1 2083827 2084123 R KEGG: dat:HRM2_19160 hypothetical protein; hypothetical protein complement(2083827..2084123) Kosmotoga olearia TBF 19.5.1 7968459 YP_002941654.1 CDS Kole_1969 NC_012785.1 2084146 2084901 R KEGG: shn:Shewana3_2240 hypothetical protein; hypothetical protein complement(2084146..2084901) Kosmotoga olearia TBF 19.5.1 7968460 YP_002941655.1 CDS Kole_1970 NC_012785.1 2085064 2085738 R hypothetical protein complement(2085064..2085738) Kosmotoga olearia TBF 19.5.1 7968461 YP_002941656.1 CDS Kole_1971 NC_012785.1 2085739 2089005 R KEGG: sfu:Sfum_0410 hypothetical protein; hypothetical protein complement(2085739..2089005) Kosmotoga olearia TBF 19.5.1 7968462 YP_002941657.1 CDS Kole_1972 NC_012785.1 2089019 2092249 R PFAM: helicase domain protein; SNF2-related protein; type III restriction protein res subunit; SMART: helicase domain protein; DEAD-like helicase; KEGG: sfu:Sfum_0411 helicase domain protein; helicase domain protein complement(2089019..2092249) Kosmotoga olearia TBF 19.5.1 7968463 YP_002941658.1 CDS Kole_1973 NC_012785.1 2092773 2093999 D PFAM: ROK family protein; KEGG: bha:BH2758 transcriptional repressor of the xylose operon; ROK family protein 2092773..2093999 Kosmotoga olearia TBF 19.5.1 7968464 YP_002941659.1 CDS Kole_1974 NC_012785.1 2093996 2094877 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ret:RHE_PF00302 sugar ABC transporter, permease protein; binding-protein-dependent transport systems inner membrane component 2093996..2094877 Kosmotoga olearia TBF 19.5.1 7968465 YP_002941660.1 CDS Kole_1975 NC_012785.1 2094874 2095689 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rlt:Rleg2_5335 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 2094874..2095689 Kosmotoga olearia TBF 19.5.1 7968466 YP_002941661.1 CDS Kole_1976 NC_012785.1 2095710 2096936 D PFAM: extracellular solute-binding protein family 1; KEGG: spe:Spro_2571 extracellular solute-binding protein; extracellular solute-binding protein family 1 2095710..2096936 Kosmotoga olearia TBF 19.5.1 7968467 YP_002941662.1 CDS Kole_1977 NC_012785.1 2096954 2099329 D PFAM: glycoside hydrolase family 31; KEGG: spq:SPAB_00051 hypothetical protein; glycoside hydrolase family 31 2096954..2099329 Kosmotoga olearia TBF 19.5.1 7968468 YP_002941663.1 CDS Kole_1978 NC_012785.1 2099334 2100374 D PFAM: glycoside hydrolase 15-related; KEGG: xac:XAC4082 hypothetical protein; glycoside hydrolase 15-related 2099334..2100374 Kosmotoga olearia TBF 19.5.1 7967576 YP_002941664.1 CDS Kole_1979 NC_012785.1 2101101 2101397 R KEGG: sun:SUN_0582 hypothetical protein; hypothetical protein complement(2101101..2101397) Kosmotoga olearia TBF 19.5.1 7967577 YP_002941665.1 CDS Kole_1980 NC_012785.1 2101384 2101581 R hypothetical protein complement(2101384..2101581) Kosmotoga olearia TBF 19.5.1 7967578 YP_002941666.1 CDS Kole_1982 NC_012785.1 2102238 2102876 D PFAM: Domain of unknown function DUF1814; KEGG: dol:Dole_1847 hypothetical protein; hypothetical protein 2102238..2102876 Kosmotoga olearia TBF 19.5.1 7967580 YP_002941667.1 CDS Kole_1983 NC_012785.1 2103680 2104759 R PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: rec:RHECIAT_CH0002176 iron(III) ABC transporter, ATP-binding protein; ABC transporter complement(2103680..2104759) Kosmotoga olearia TBF 19.5.1 7967581 YP_002941668.1 CDS Kole_1984 NC_012785.1 2104765 2106960 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pde:Pden_4650 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component complement(2104765..2106960) Kosmotoga olearia TBF 19.5.1 7967582 YP_002941669.1 CDS Kole_1985 NC_012785.1 2107059 2108042 R PFAM: extracellular solute-binding protein family 1; KEGG: bmi:BMEA_B0695 ABC transporter iron-binding protein; extracellular solute-binding protein family 1 complement(2107059..2108042) Kosmotoga olearia TBF 19.5.1 7967583 YP_002941670.1 CDS Kole_1986 NC_012785.1 2108502 2109359 R PFAM: ATPase BadF/BadG/BcrA/BcrD type; KEGG: NAGK; N-acetylglucosamine kinase; K00884 N-acetylglucosamine kinase; ATPase BadF/BadG/BcrA/BcrD type complement(2108502..2109359) Kosmotoga olearia TBF 19.5.1 7967584 YP_002941671.1 CDS Kole_1987 NC_012785.1 2109356 2110084 R PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: bar:GBAA4272 GntR family transcriptional regulator; GntR family transcriptional regulator complement(2109356..2110084) Kosmotoga olearia TBF 19.5.1 7967585 YP_002941672.1 CDS murQ NC_012785.1 2110081 2110986 R catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid-6-phosphate etherase complement(2110081..2110986) Kosmotoga olearia TBF 19.5.1 7967586 YP_002941673.1 CDS Kole_1989 NC_012785.1 2111038 2112552 R PFAM: glycoside hydrolase family 3 domain protein; KEGG: bha:BH0675 beta-hexosamidase A precursor; Beta-N-acetylhexosaminidase complement(2111038..2112552) Kosmotoga olearia TBF 19.5.1 7967587 YP_002941674.1 CDS Kole_1990 NC_012785.1 2112542 2113660 R PFAM: conserved hypothetical protein; KEGG: bsu:BSU01650 hypothetical protein; hypothetical protein complement(2112542..2113660) Kosmotoga olearia TBF 19.5.1 7967588 YP_002941675.1 CDS Kole_1991 NC_012785.1 2113999 2114850 D KEGG: dvl:Dvul_0199 NLP/P60 protein; hypothetical protein 2113999..2114850 Kosmotoga olearia TBF 19.5.1 7967589 YP_002941676.1 CDS Kole_1992 NC_012785.1 2114872 2116131 D PFAM: extracellular solute-binding protein family 1; KEGG: sme:SM_b20971 sugar uptake ABC transporter periplasmic solute-binding protein precursor; extracellular solute-binding protein family 1 2114872..2116131 Kosmotoga olearia TBF 19.5.1 7967590 YP_002941677.1 CDS Kole_1993 NC_012785.1 2116132 2116995 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bha:BH3689 sugar transport system (permease); binding-protein-dependent transport systems inner membrane component 2116132..2116995 Kosmotoga olearia TBF 19.5.1 7967591 YP_002941678.1 CDS Kole_1994 NC_012785.1 2117020 2117841 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: smt:Smal_2681 monosaccharide-transporting ATPase; binding-protein-dependent transport systems inner membrane component 2117020..2117841 Kosmotoga olearia TBF 19.5.1 7967592 YP_002941679.1 CDS Kole_1995 NC_012785.1 2117825 2118919 D PFAM: protein of unknown function DUF187; KEGG: bsu:BSU18280 hypothetical protein; hypothetical protein 2117825..2118919 Kosmotoga olearia TBF 19.5.1 7967593 YP_002941680.1 CDS Kole_1996 NC_012785.1 2118949 2119767 D KEGG: rle:RL3795 hypothetical protein; hypothetical protein 2118949..2119767 Kosmotoga olearia TBF 19.5.1 7967594 YP_002941681.1 CDS Kole_1997 NC_012785.1 2119905 2121491 D PFAM: cell wall hydrolase/autolysin; SMART: cell wall hydrolase/autolysin; KEGG: bsu:BSU01530 N-acetylmuramoyl-L-alanine amidase; cell wall hydrolase/autolysin 2119905..2121491 Kosmotoga olearia TBF 19.5.1 7967595 YP_002941682.1 CDS Kole_1998 NC_012785.1 2121594 2122388 D PFAM: Electron transfer flavoprotein alpha/beta-subunit; KEGG: sfu:Sfum_1372 electron transfer flavoprotein beta-subunit; Electron transfer flavoprotein alpha/beta-subunit 2121594..2122388 Kosmotoga olearia TBF 19.5.1 7967596 YP_002941683.1 CDS Kole_1999 NC_012785.1 2122385 2123398 D PFAM: Electron transfer flavoprotein alpha subunit ; Electron transfer flavoprotein alpha/beta-subunit; KEGG: sfu:Sfum_1373 electron transfer flavoprotein, alpha subunit; Electron transfer flavoprotein alpha subunit 2122385..2123398 Kosmotoga olearia TBF 19.5.1 7967597 YP_002941684.1 CDS Kole_2000 NC_012785.1 2123395 2124795 D PFAM: FAD linked oxidase domain protein; KEGG: gur:Gura_0648 FAD linked oxidase domain-containing protein; FAD linked oxidase domain protein 2123395..2124795 Kosmotoga olearia TBF 19.5.1 7967598 YP_002941685.1 CDS Kole_2001 NC_012785.1 2124895 2125713 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bha:BH3847 ABC transporter (permease); binding-protein-dependent transport systems inner membrane component complement(2124895..2125713) Kosmotoga olearia TBF 19.5.1 7967599 YP_002941686.1 CDS Kole_2002 NC_012785.1 2125710 2126648 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bha:BH3846 ABC transporter (permease); binding-protein-dependent transport systems inner membrane component complement(2125710..2126648) Kosmotoga olearia TBF 19.5.1 7967600 YP_002941687.1 CDS Kole_2003 NC_012785.1 2126697 2127932 R PFAM: extracellular solute-binding protein family 1; KEGG: bha:BH3845 ABC transporter (substrate-binding protein); extracellular solute-binding protein family 1 complement(2126697..2127932) Kosmotoga olearia TBF 19.5.1 7967601 YP_002941688.1 CDS Kole_2004 NC_012785.1 2127988 2129148 R PFAM: ROK family protein; KEGG: bha:BH1094 transcriptional repressor of the xylose operon; ROK family protein complement(2127988..2129148) Kosmotoga olearia TBF 19.5.1 7967602 YP_002941689.1 CDS Kole_2005 NC_012785.1 2129401 2130696 R PFAM: peptidase S41; KEGG: sus:Acid_0918 peptidase S41; peptidase S41 complement(2129401..2130696) Kosmotoga olearia TBF 19.5.1 7967603 YP_002941690.1 CDS Kole_2006 NC_012785.1 2130958 2132271 D PFAM: ATPase; KEGG: sat:SYN_01506 ATPase; ATPase 2130958..2132271 Kosmotoga olearia TBF 19.5.1 7967604 YP_002941691.1 CDS Kole_2007 NC_012785.1 2132364 2134355 R PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: bha:BH2927 maltogenic amylase; alpha amylase catalytic region complement(2132364..2134355) Kosmotoga olearia TBF 19.5.1 7967605 YP_002941692.1 CDS Kole_2008 NC_012785.1 2134605 2135978 D PFAM: ATPase; DUF234 DEXX-box ATPase; KEGG: sat:SYN_01513 ATPase; ATPase 2134605..2135978 Kosmotoga olearia TBF 19.5.1 7967606 YP_002941693.1 CDS Kole_2011 NC_012785.1 2138670 2140184 R TIGRFAM: integral membrane protein MviN; PFAM: virulence factor MVIN family protein; multi antimicrobial extrusion protein MatE; KEGG: sat:SYN_00104 virulence factor protein; integral membrane protein MviN complement(2138670..2140184) Kosmotoga olearia TBF 19.5.1 7967609 YP_002941694.1 CDS Kole_2012 NC_012785.1 2140324 2140740 D PFAM: protein of unknown function DUF296; KEGG: sus:Acid_2059 hypothetical protein; hypothetical protein 2140324..2140740 Kosmotoga olearia TBF 19.5.1 7967610 YP_002941695.1 CDS Kole_2013 NC_012785.1 2140743 2141906 R PFAM: major facilitator superfamily MFS_1; KEGG: hypothetical protein; major facilitator superfamily MFS_1 complement(2140743..2141906) Kosmotoga olearia TBF 19.5.1 7967611 YP_002941696.1 CDS Kole_2014 NC_012785.1 2141914 2142549 R hypothetical protein complement(2141914..2142549) Kosmotoga olearia TBF 19.5.1 7967612 YP_002941697.1 CDS Kole_2015 NC_012785.1 2142554 2143324 R PFAM: Methyltransferase type 11; UbiE/COQ5 methyltransferase; Methyltransferase type 12; KEGG: msu:MS0467 SmtA protein; Methyltransferase type 11 complement(2142554..2143324) Kosmotoga olearia TBF 19.5.1 7967613 YP_002941698.1 CDS Kole_2016 NC_012785.1 2143317 2146016 R KEGG: mxa:MXAN_5791 response regulator/GGDEF domain protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; diguanylate cyclase complement(2143317..2146016) Kosmotoga olearia TBF 19.5.1 7967614 YP_002941699.1 CDS Kole_2017 NC_012785.1 2146286 2148067 D PFAM: peptidase M3A and M3B thimet/oligopeptidase F; Oligopeptidase F; KEGG: gur:Gura_2055 PepF/M3 family oligoendopeptidase; peptidase M3A and M3B thimet/oligopeptidase F 2146286..2148067 Kosmotoga olearia TBF 19.5.1 7967615 YP_002941700.1 CDS Kole_2018 NC_012785.1 2148272 2149783 D KEGG: nam:NAMH_1489 DNA polymerase III, subunits gamma and tau; TIGRFAM: DNA polymerase III, subunits gamma and tau; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; DNA polymerase III, subunits gamma and tau 2148272..2149783 Kosmotoga olearia TBF 19.5.1 7967616 YP_002941701.1 CDS Kole_2019 NC_012785.1 2149776 2150144 D PFAM: conserved hypothetical protein; KEGG: bha:BH0035 hypothetical protein; hypothetical protein 2149776..2150144 Kosmotoga olearia TBF 19.5.1 7967617 YP_002941702.1 CDS Kole_2020 NC_012785.1 2150171 2151166 D KEGG: glo:Glov_1616 glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase, type I 2150171..2151166 Kosmotoga olearia TBF 19.5.1 7967618 YP_002941703.1 CDS pgk NC_012785.1 2151239 2152456 D Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 2151239..2152456 Kosmotoga olearia TBF 19.5.1 7967619 YP_002941704.1 CDS Kole_2022 NC_012785.1 2152456 2153205 D TIGRFAM: triosephosphate isomerase; PFAM: triosephosphate isomerase; KEGG: pca:Pcar_1333 triosephosphate isomerase; triosephosphate isomerase 2152456..2153205 Kosmotoga olearia TBF 19.5.1 7967620 YP_002941705.1 CDS Kole_2023 NC_012785.1 2153301 2153555 D KEGG: conserved hypothetical protein; hypothetical protein 2153301..2153555 Kosmotoga olearia TBF 19.5.1 7967621 YP_002941706.1 CDS Kole_2024 NC_012785.1 2153552 2153839 D hypothetical protein 2153552..2153839 Kosmotoga olearia TBF 19.5.1 7967622 YP_002941707.1 CDS Kole_2025 NC_012785.1 2153823 2154656 D KEGG: gme:Gmet_0547 glutamate racemase; TIGRFAM: glutamate racemase; PFAM: Asp/Glu/hydantoin racemase; glutamate racemase 2153823..2154656 Kosmotoga olearia TBF 19.5.1 7967623 YP_002941708.1 CDS Kole_2026 NC_012785.1 2154662 2155510 D PFAM: conserved hypothetical protein; KEGG: bsu:BSU34770 hypothetical protein; hypothetical protein 2154662..2155510 Kosmotoga olearia TBF 19.5.1 7967624 YP_002941709.1 CDS Kole_2027 NC_012785.1 2155504 2156106 R PFAM: transposase IS4 family protein; KEGG: dol:Dole_3091 transposase IS4 family protein; transposase IS4 family protein complement(2155504..2156106) Kosmotoga olearia TBF 19.5.1 7967625 YP_002941710.1 CDS Kole_2028 NC_012785.1 2156090 2156470 R hypothetical protein complement(2156090..2156470) Kosmotoga olearia TBF 19.5.1 7967626 YP_002941711.1 CDS Kole_2029 NC_012785.1 2156606 2157568 D PFAM: protein of unknown function UPF0052 and CofD; KEGG: sus:Acid_4363 protein of unknown function UPF0052 and CofD; hypothetical protein 2156606..2157568 Kosmotoga olearia TBF 19.5.1 7967627 YP_002941712.1 CDS Kole_2030 NC_012785.1 2157565 2158509 D PFAM: protein of unknown function DUF199; KEGG: bsu:BSU34750 hypothetical protein; hypothetical protein 2157565..2158509 Kosmotoga olearia TBF 19.5.1 7967628 YP_002941713.1 CDS Kole_2031 NC_012785.1 2158490 2158966 D PFAM: ATP-cone domain protein; KEGG: bsu:BSU29000 transcriptional regulator NrdR; ATP-cone domain protein 2158490..2158966 Kosmotoga olearia TBF 19.5.1 7967629 YP_002941714.1 CDS greA NC_012785.1 2158968 2159444 D necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 2158968..2159444 Kosmotoga olearia TBF 19.5.1 7967630 YP_002941715.1 CDS lysS NC_012785.1 2159459 2160973 D class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 2159459..2160973 Kosmotoga olearia TBF 19.5.1 7967631 YP_002941716.1 CDS Kole_2034 NC_012785.1 2160985 2161446 D KEGG: dds:Ddes_1088 GatB/YqeY domain-containing protein; GatB/YqeY domain-containing protein 2160985..2161446 Kosmotoga olearia TBF 19.5.1 7967632 YP_002941717.1 CDS Kole_2035 NC_012785.1 2161448 2162815 D KEGG: ecf:ECH74115_0831 glutamate mutase MutL; glutamate mutase MutL 2161448..2162815 Kosmotoga olearia TBF 19.5.1 7967633 YP_002941718.1 CDS Kole_2036 NC_012785.1 2162978 2163517 R KEGG: dat:HRM2_08780 FolA; FolA complement(2162978..2163517) Kosmotoga olearia TBF 19.5.1 7967635 YP_002941719.1 CDS Kole_2037 NC_012785.1 2163514 2164458 R hypothetical protein complement(2163514..2164458) Kosmotoga olearia TBF 19.5.1 7967636 YP_002941720.1 CDS Kole_2038 NC_012785.1 2164626 2166575 D hypothetical protein 2164626..2166575 Kosmotoga olearia TBF 19.5.1 7967637 YP_002941721.1 CDS Kole_2039 NC_012785.1 2166529 2167236 D PFAM: Methyltransferase type 11; methyltransferase small; Methyltransferase type 12; RNA methylase; KEGG: gme:Gmet_2876 RNA methylase:methyltransferase small; Methyltransferase type 11 2166529..2167236 Kosmotoga olearia TBF 19.5.1 7967638 YP_002941722.1 CDS Kole_2040 NC_012785.1 2167239 2167865 D KEGG: ppd:Ppro_1665 dTMP kinase; TIGRFAM: thymidylate kinase; PFAM: thymidylate kinase; thymidylate kinase 2167239..2167865 Kosmotoga olearia TBF 19.5.1 7967639 YP_002941723.1 CDS Kole_2041 NC_012785.1 2167880 2170366 D PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Torsin; UvrB/UvrC protein; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: AAA ATPase; KEGG: baa:BA_0670 Clp_N, Clp amino terminal domain; ATPase AAA-2 domain protein 2167880..2170366 Kosmotoga olearia TBF 19.5.1 7967640 YP_002941724.1 CDS Kole_2042 NC_012785.1 2170363 2171691 D TIGRFAM: DNA repair protein RadA; SMART: AAA ATPase; KEGG: dat:HRM2_03980 RadA; DNA repair protein RadA 2170363..2171691 Kosmotoga olearia TBF 19.5.1 7967641 YP_002941725.1 CDS Kole_2043 NC_012785.1 2171681 2172748 D non-specific DNA-binding; scans chromosomes during sporulation for DNA-damage; delays initiation of sporulation; participates in a checkpoint signaling cascade for cell-cycle progression and DNA repair; DNA integrity scanning protein DisA 2171681..2172748 Kosmotoga olearia TBF 19.5.1 7967642 YP_002941726.1 CDS Kole_2044 NC_012785.1 2172750 2174036 R KEGG: Amidohydrolase family protein; Cytosine deaminase and related metal-dependent hydrolase-like protein complement(2172750..2174036) Kosmotoga olearia TBF 19.5.1 7967643 YP_002941727.1 CDS Kole_2045 NC_012785.1 2174026 2174772 R KEGG: spl:Spea_1424 WecB/TagA/CpsF family glycosyl transferase; TIGRFAM: glycosyl transferase, WecB/TagA/CpsF family; PFAM: glycosyl transferase WecB/TagA/CpsF; glycosyl transferase, WecB/TagA/CpsF family complement(2174026..2174772) Kosmotoga olearia TBF 19.5.1 7967644 YP_002941728.1 CDS Kole_2046 NC_012785.1 2175114 2176619 D PFAM: extracellular solute-binding protein family 5; KEGG: mlo:mlr6670 oligopeptide ABC transporter, periplasmic oligopeptide-binding protein; extracellular solute-binding protein family 5 2175114..2176619 Kosmotoga olearia TBF 19.5.1 7967646 YP_002941729.1 CDS Kole_2047 NC_012785.1 2176682 2177689 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bha:BH3643 dipeptide ABC transporter (permease); binding-protein-dependent transport systems inner membrane component 2176682..2177689 Kosmotoga olearia TBF 19.5.1 7967647 YP_002941730.1 CDS Kole_2048 NC_012785.1 2177703 2178584 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bar:GBAA4731 oligopeptide ABC transporter, oligopeptide-binding protein; binding-protein-dependent transport systems inner membrane component 2177703..2178584 Kosmotoga olearia TBF 19.5.1 7967648 YP_002941731.1 CDS Kole_2049 NC_012785.1 2178589 2179560 D KEGG: dde:Dde_1182 oligopeptide/dipeptide ABC transporter, ATP-binding protein-like; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; peptide ABC transporter ATPase 2178589..2179560 Kosmotoga olearia TBF 19.5.1 7967649 YP_002941732.1 CDS Kole_2050 NC_012785.1 2179557 2180543 D KEGG: bha:BH3645 oligopeptide ABC transporter ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; peptide ABC transporter ATPase 2179557..2180543 Kosmotoga olearia TBF 19.5.1 7967650 YP_002941733.1 CDS Kole_2051 NC_012785.1 2180578 2182392 R PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mgm:Mmc1_2205 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; oxidoreductase complement(2180578..2182392) Kosmotoga olearia TBF 19.5.1 7967651 YP_002941734.1 CDS Kole_2052 NC_012785.1 2182406 2183512 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D complement(2182406..2183512) Kosmotoga olearia TBF 19.5.1 7967652 YP_002941735.1 CDS Kole_2053 NC_012785.1 2183505 2184020 R PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit; KEGG: mgm:Mmc1_2207 NADH dehydrogenase (ubiquinone), 30 kDa subunit; NADH dehydrogenase (ubiquinone) 30 kDa subunit complement(2183505..2184020) Kosmotoga olearia TBF 19.5.1 7967653 YP_002941736.1 CDS Kole_2054 NC_012785.1 2184004 2184543 R The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B complement(2184004..2184543) Kosmotoga olearia TBF 19.5.1 7967654 YP_002941737.1 CDS Kole_2055 NC_012785.1 2184557 2185438 R PFAM: respiratory-chain NADH dehydrogenase subunit 1; KEGG: mgm:Mmc1_2209 membrane bound protein complex subunit MbxM; respiratory-chain NADH dehydrogenase subunit 1 complement(2184557..2185438) Kosmotoga olearia TBF 19.5.1 7967655 YP_002941738.1 CDS Kole_2056 NC_012785.1 2185443 2187278 R PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: mgm:Mmc1_2210 NADH dehydrogenase (quinone); NADH dehydrogenase subunit M complement(2185443..2187278) Kosmotoga olearia TBF 19.5.1 7967656 YP_002941739.1 CDS Kole_2057 NC_012785.1 2187279 2188724 R PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: wol:WD1107 monovalent cation/H+ antiporter subunit D; NADH/Ubiquinone/plastoquinone (complex I) complement(2187279..2188724) Kosmotoga olearia TBF 19.5.1 7969232 YP_002941740.1 CDS Kole_2058 NC_012785.1 2188721 2189062 R PFAM: NADH-ubiquinone oxidoreductase chain 4L; KEGG: mgm:Mmc1_2211 membrane bound protein complex subunit MbxG; NADH-ubiquinone oxidoreductase chain 4L complement(2188721..2189062) Kosmotoga olearia TBF 19.5.1 7968469 YP_002941741.1 CDS Kole_2059 NC_012785.1 2189059 2189814 R subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit B complement(2189059..2189814) Kosmotoga olearia TBF 19.5.1 7968470 YP_002941742.1 CDS Kole_2060 NC_012785.1 2189811 2190053 R KEGG: ecn:Ecaj_0558 monovalent cation/H+ antiporter subunit B; monovalent cation/H+ antiporter subunit B complement(2189811..2190053) Kosmotoga olearia TBF 19.5.1 7968471 YP_002941743.1 CDS Kole_2061 NC_012785.1 2190050 2190394 R subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport; monovalent cation/H+ antiporter subunit G complement(2190050..2190394) Kosmotoga olearia TBF 19.5.1 7968472 YP_002941744.1 CDS Kole_2062 NC_012785.1 2190391 2190642 R subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport; monovalent cation/H+ antiporter subunit F complement(2190391..2190642) Kosmotoga olearia TBF 19.5.1 7968473 YP_002941745.1 CDS Kole_2063 NC_012785.1 2190639 2191130 R PFAM: cation antiporter; KEGG: mgm:Mmc1_2216 membrane bound protein complex subunit MbxA; cation antiporter complement(2190639..2191130) Kosmotoga olearia TBF 19.5.1 7968474 YP_002941746.1 CDS Kole_2064 NC_012785.1 2191464 2191664 D PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: sat:SYN_01437 cold shock protein; cold-shock DNA-binding domain protein 2191464..2191664 Kosmotoga olearia TBF 19.5.1 7968475 YP_002941747.1 CDS Kole_2065 NC_012785.1 2191759 2192628 D TIGRFAM: degV family protein; PFAM: DegV family protein; KEGG: bsu:BSU11110 hypothetical protein; degV family protein 2191759..2192628 Kosmotoga olearia TBF 19.5.1 7968476 YP_002941748.1 CDS Kole_2066 NC_012785.1 2192659 2194014 R PFAM: amidohydrolase; Amidohydrolase 3; KEGG: bcj:BCAL2029 hydroxydechloroatrazine ethylaminohydrolase; amidohydrolase complement(2192659..2194014) Kosmotoga olearia TBF 19.5.1 7968477 YP_002941749.1 CDS Kole_2068 NC_012785.1 2194749 2195588 D PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: Os07g0657900; hypothetical protein; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 2194749..2195588 Kosmotoga olearia TBF 19.5.1 7968479 YP_002941750.1 CDS Kole_2069 NC_012785.1 2195603 2196577 D KEGG: wsu:WS0062 hypothetical protein; Fe-S-cluster redox enzyme-like protein 2195603..2196577 Kosmotoga olearia TBF 19.5.1 7968480 YP_002941751.1 CDS Kole_2070 NC_012785.1 2196681 2197880 D Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases; peptidase 2196681..2197880 Kosmotoga olearia TBF 19.5.1 7968481 YP_002941752.1 CDS Kole_2071 NC_012785.1 2197893 2198882 D PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; KEGG: spe:Spro_3190 ornithine carbamoyltransferase; Ornithine carbamoyltransferase 2197893..2198882 Kosmotoga olearia TBF 19.5.1 7968482 YP_002941753.1 CDS Kole_2072 NC_012785.1 2198879 2200246 D PFAM: amidohydrolase; KEGG: D-hydantoinase ; K01465 dihydroorotase; amidohydrolase 2198879..2200246 Kosmotoga olearia TBF 19.5.1 7968483 YP_002941754.1 CDS Kole_2073 NC_012785.1 2200249 2201553 D PFAM: amidohydrolase; Amidohydrolase 3; KEGG: Amidohydrolase family protein; amidohydrolase 2200249..2201553 Kosmotoga olearia TBF 19.5.1 7968484 YP_002941755.1 CDS Kole_2074 NC_012785.1 2201573 2202658 D TIGRFAM: dihydroorotate dehydrogenase family protein; PFAM: dihydroorotate dehydrogenase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dihydroorotate dehydrogenase family protein; dihydroorotate dehydrogenase family protein 2201573..2202658 Kosmotoga olearia TBF 19.5.1 7968485 YP_002941756.1 CDS Kole_2075 NC_012785.1 2202655 2203914 D TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: pfo:Pfl01_2313 L-threonine synthase; threonine synthase 2202655..2203914 Kosmotoga olearia TBF 19.5.1 7968486 YP_002941757.1 CDS Kole_2076 NC_012785.1 2203898 2204368 D PFAM: [2Fe-2S]-binding domain protein; ferredoxin; KEGG: sfu:Sfum_2011 (2Fe-2S)-binding domain protein; (2Fe-2S)-binding domain protein 2203898..2204368 Kosmotoga olearia TBF 19.5.1 7968487 YP_002941758.1 CDS Kole_2077 NC_012785.1 2204361 2204996 D KEGG: mlo:mlr0093 hypothetical protein; hypothetical protein 2204361..2204996 Kosmotoga olearia TBF 19.5.1 7968488 YP_002941759.1 CDS Kole_2078 NC_012785.1 2204950 2205717 D KEGG: sus:Acid_2901 hypothetical protein; hypothetical protein 2204950..2205717 Kosmotoga olearia TBF 19.5.1 7968489 YP_002941760.1 CDS Kole_2079 NC_012785.1 2205741 2206592 D PFAM: molybdopterin dehydrogenase FAD-binding; CO dehydrogenase flavoprotein domain protein; KEGG: dat:HRM2_37990 two-component fusion protein (N:molybdopterin dehydrogenase, FAD-binding domain-C:carbon monoxide dehydrogenase medium chain); molybdopterin dehydrogenase FAD-binding 2205741..2206592 Kosmotoga olearia TBF 19.5.1 7968490 YP_002941761.1 CDS Kole_2080 NC_012785.1 2206576 2207412 D PFAM: molybdopterin dehydrogenase FAD-binding; CO dehydrogenase flavoprotein domain protein; KEGG: dps:DP3068 4-hydroxybenzoyl-CoA reductase HcrB; molybdopterin dehydrogenase FAD-binding 2206576..2207412 Kosmotoga olearia TBF 19.5.1 7968491 YP_002941762.1 CDS Kole_2081 NC_012785.1 2207409 2207882 D PFAM: [2Fe-2S]-binding domain protein; ferredoxin; KEGG: reu:Reut_B3596 ferredoxin:(2Fe-2S)-binding; (2Fe-2S)-binding domain protein 2207409..2207882 Kosmotoga olearia TBF 19.5.1 7968492 YP_002941763.1 CDS Kole_2082 NC_012785.1 2207875 2210214 D PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; KEGG: dps:DP3066 4-hydroxybenzoyl-CoA reductase HcrA; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding 2207875..2210214 Kosmotoga olearia TBF 19.5.1 7968493 YP_002941764.1 CDS Kole_2083 NC_012785.1 2210211 2211344 D PFAM: extracellular solute-binding protein family 1; KEGG: aha:AHA_1667 maltose ABC transporter periplasmic protein; extracellular solute-binding protein family 1 2210211..2211344 Kosmotoga olearia TBF 19.5.1 7968494 YP_002941765.1 CDS Kole_2084 NC_012785.1 2211418 2213397 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bbt:BBta_3987 sugar ABC transporter (permease protein); binding-protein-dependent transport systems inner membrane component 2211418..2213397 Kosmotoga olearia TBF 19.5.1 7968495 YP_002941766.1 CDS Kole_2085 NC_012785.1 2213390 2214136 D PFAM: protein of unknown function DUF364; KEGG: dps:DP2969 hypothetical protein; hypothetical protein 2213390..2214136 Kosmotoga olearia TBF 19.5.1 7968496 YP_002941767.1 CDS Kole_2086 NC_012785.1 2214168 2215553 R PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: Pyridoxal-phosphate dependent enzyme family protein; Pyridoxal-5'-phosphate-dependent protein beta subunit complement(2214168..2215553) Kosmotoga olearia TBF 19.5.1 7968497 YP_002941768.1 CDS Kole_2087 NC_012785.1 2215558 2217858 R PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; KEGG: afr:AFE_0775 xanthine dehydrogenase, molybdenum-binding subunit; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding complement(2215558..2217858) Kosmotoga olearia TBF 19.5.1 7968498 YP_002941769.1 CDS Kole_2088 NC_012785.1 2217863 2219596 R KEGG: dal:Dalk_3756 adenine deaminase; TIGRFAM: adenine deaminase; PFAM: amidohydrolase; adenine deaminase complement(2217863..2219596) Kosmotoga olearia TBF 19.5.1 7968499 YP_002941770.1 CDS thrS NC_012785.1 2219735 2221681 R catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase complement(2219735..2221681) Kosmotoga olearia TBF 19.5.1 7968500 YP_002941771.1 CDS Kole_2090 NC_012785.1 2221696 2222079 R TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; KEGG: vfm:VFMJ11_0394 endoribonuclease L-PSP; endoribonuclease L-PSP complement(2221696..2222079) Kosmotoga olearia TBF 19.5.1 7968501 YP_002941772.1 CDS Kole_2091 NC_012785.1 2222228 2222722 R hypothetical protein complement(2222228..2222722) Kosmotoga olearia TBF 19.5.1 7968502 YP_002941773.1 CDS Kole_2092 NC_012785.1 2223289 2224998 R PFAM: peptidase C11 clostripain; KEGG: gme:Gmet_1209 hypothetical protein; peptidase C11 clostripain complement(2223289..2224998) Kosmotoga olearia TBF 19.5.1 7968503 YP_002941774.1 CDS Kole_2093 NC_012785.1 2225101 2225586 R TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate beta region; KEGG: nam:NAMH_1232 C-terminal fumarate hydratase, class I; hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit complement(2225101..2225586) Kosmotoga olearia TBF 19.5.1 7968504 YP_002941775.1 CDS Kole_2094 NC_012785.1 2225567 2226394 R TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; KEGG: cha:CHAB381_0023 fumarate hydratase; hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit complement(2225567..2226394) Kosmotoga olearia TBF 19.5.1 7968505 YP_002941776.1 CDS Kole_2095 NC_012785.1 2226471 2227307 R TIGRFAM: phenazine biosynthesis protein PhzF family; PFAM: Phenazine biosynthesis PhzC/PhzF protein; KEGG: sus:Acid_1799 PhzF family phenazine biosynthesis protein; phenazine biosynthesis protein PhzF family complement(2226471..2227307) Kosmotoga olearia TBF 19.5.1 7968506 YP_002941777.1 CDS Kole_2096 NC_012785.1 2227326 2227766 R hypothetical protein complement(2227326..2227766) Kosmotoga olearia TBF 19.5.1 7968507 YP_002941778.1 CDS Kole_2097 NC_012785.1 2227917 2228414 D KEGG: acp:A2cp1_2187 hypothetical protein; hypothetical protein 2227917..2228414 Kosmotoga olearia TBF 19.5.1 7968508 YP_002941779.1 CDS Kole_2098 NC_012785.1 2228421 2228765 R PFAM: protein of unknown function DUF437; KEGG: bha:BH0816 hypothetical protein; hypothetical protein complement(2228421..2228765) Kosmotoga olearia TBF 19.5.1 7968509 YP_002941780.1 CDS Kole_2099 NC_012785.1 2228834 2229538 R PFAM: GCN5-related N-acetyltransferase; KEGG: similar to CG5783 CG5783-PA; GCN5-related N-acetyltransferase complement(2228834..2229538) Kosmotoga olearia TBF 19.5.1 7968510 YP_002941781.1 CDS Kole_2100 NC_012785.1 2229824 2230615 D PFAM: alpha/beta hydrolase fold; KEGG: dol:Dole_2799 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 2229824..2230615 Kosmotoga olearia TBF 19.5.1 7968512 YP_002941782.1 CDS Kole_2101 NC_012785.1 2230601 2231500 R TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; KEGG: dal:Dalk_0550 riboflavin biosynthesis protein RibF; riboflavin biosynthesis protein RibF complement(2230601..2231500) Kosmotoga olearia TBF 19.5.1 7968513 YP_002941783.1 CDS Kole_2102 NC_012785.1 2231493 2232422 R catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B complement(2231493..2232422) Kosmotoga olearia TBF 19.5.1 7968514 YP_002941784.1 CDS Kole_2103 NC_012785.1 2232419 2232796 R TIGRFAM: ribosome-binding factor A; PFAM: ribosome-binding factor A; KEGG: pat:Patl_1696 ribosome-binding factor A; ribosome-binding factor A complement(2232419..2232796) Kosmotoga olearia TBF 19.5.1 7968515 YP_002941785.1 CDS Kole_2104 NC_012785.1 2232888 2234174 R PFAM: Patatin; KEGG: cha:CHAB381_0344 patatin family phospholipase; Patatin complement(2232888..2234174) Kosmotoga olearia TBF 19.5.1 7968516 YP_002941786.1 CDS Kole_2105 NC_012785.1 2234469 2236199 D PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; KEGG: baa:BA_4222 ABC transporter transmembrane region; ABC transporter 2234469..2236199 Kosmotoga olearia TBF 19.5.1 7968517 YP_002941787.1 CDS Kole_2106 NC_012785.1 2236205 2238151 D PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; KEGG: aba:Acid345_2371 ABC transporter, ATPase subunit; ABC transporter 2236205..2238151 Kosmotoga olearia TBF 19.5.1 7968518 YP_002941788.1 CDS Kole_2107 NC_012785.1 2238295 2239212 R TIGRFAM: GTP-binding protein Era; small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; KH type 2 domain protein; Miro domain protein; KEGG: baa:BA_4971 MMR_HSR1, GTPase of unknown function; GTP-binding protein Era complement(2238295..2239212) Kosmotoga olearia TBF 19.5.1 7968519 YP_002941789.1 CDS Kole_2108 NC_012785.1 2239209 2241260 R KEGG: bsu:BSU25260 glycyl-tRNA synthetase subunit beta; TIGRFAM: glycyl-tRNA synthetase, beta subunit; glycyl-tRNA synthetase, beta subunit complement(2239209..2241260) Kosmotoga olearia TBF 19.5.1 7968520 YP_002941790.1 CDS glyQ NC_012785.1 2241257 2242108 R glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha complement(2241257..2242108) Kosmotoga olearia TBF 19.5.1 7968521 YP_002941791.1 CDS Kole_2110 NC_012785.1 2242122 2243786 R PFAM: Dak phosphatase; KEGG: bsu:BSU15840 hypothetical protein; Dak phosphatase complement(2242122..2243786) Kosmotoga olearia TBF 19.5.1 7968522 YP_002941792.1 CDS Kole_2111 NC_012785.1 2243802 2244143 R PFAM: protein of unknown function DUF322; KEGG: bha:BH2786 hypothetical protein; hypothetical protein complement(2243802..2244143) Kosmotoga olearia TBF 19.5.1 7968523 YP_002941793.1 CDS Kole_2112 NC_012785.1 2244112 2246007 R catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase complement(2244112..2246007) Kosmotoga olearia TBF 19.5.1 7968524 YP_002941794.1 CDS Kole_2113 NC_012785.1 2246009 2246842 R PFAM: tetrahydrofolate dehydrogenase/cyclohydrolase; KEGG: nmu:Nmul_A0357 methenyltetrahydrofolate cyclohydrolase; methylenetetrahydrofolate dehydrogenase complement(2246009..2246842) Kosmotoga olearia TBF 19.5.1 7968525 YP_002941795.1 CDS Kole_2114 NC_012785.1 2246853 2248523 R PFAM: formate-tetrahydrofolate ligase FTHFS; KEGG: gbe:GbCGDNIH1_0047 formate--tetrahydrofolate ligase; Formate--tetrahydrofolate ligase complement(2246853..2248523) Kosmotoga olearia TBF 19.5.1 7968526 YP_002941796.1 CDS nusB NC_012785.1 2248537 2248983 R Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB complement(2248537..2248983) Kosmotoga olearia TBF 19.5.1 7968527 YP_002941797.1 CDS Kole_2116 NC_012785.1 2249005 2249415 R PFAM: protein of unknown function DUF322; KEGG: hypothetical protein; hypothetical protein complement(2249005..2249415) Kosmotoga olearia TBF 19.5.1 7968528 YP_002941798.1 CDS Kole_2117 NC_012785.1 2249448 2250005 R Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P complement(2249448..2250005) Kosmotoga olearia TBF 19.5.1 7968529 YP_002941799.1 CDS Kole_2118 NC_012785.1 2250022 2251116 R PFAM: peptidase M24; creatinase; KEGG: bsu:BSU24460 hypothetical protein; peptidase M24 complement(2250022..2251116) Kosmotoga olearia TBF 19.5.1 7968530 YP_002941800.1 CDS Kole_2119 NC_012785.1 2251169 2253640 R This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS complement(2251169..2253640) Kosmotoga olearia TBF 19.5.1 7968531 YP_002941801.1 CDS Kole_2120 NC_012785.1 2253707 2254327 R KEGG: afw:Anae109_3421 ATP-dependent Clp protease, proteolytic subunit ClpP; TIGRFAM: ATP-dependent Clp protease, proteolytic subunit ClpP; PFAM: peptidase S14 ClpP; ATP-dependent Clp protease, proteolytic subunit ClpP complement(2253707..2254327) Kosmotoga olearia TBF 19.5.1 7968532 YP_002941802.1 CDS Kole_2121 NC_012785.1 2254347 2254598 R PFAM: protein of unknown function DUF370; KEGG: dvl:Dvul_2085 hypothetical protein; hypothetical protein complement(2254347..2254598) Kosmotoga olearia TBF 19.5.1 7968533 YP_002941803.1 CDS obgE NC_012785.1 2254660 2255973 D essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 2254660..2255973 Kosmotoga olearia TBF 19.5.1 7968534 YP_002941804.1 CDS Kole_2123 NC_012785.1 2255957 2256553 D KEGG: nis:NIS_1493 nicotinate-nucleotide adenylyltransferase; TIGRFAM: nicotinate (nicotinamide) nucleotide adenylyltransferase; cytidyltransferase-related domain protein; PFAM: cytidylyltransferase; nicotinate (nicotinamide) nucleotide adenylyltransferase 2255957..2256553 Kosmotoga olearia TBF 19.5.1 7968535 YP_002941805.1 CDS Kole_2124 NC_012785.1 2256540 2257484 D PFAM: dihydrouridine synthase DuS; KEGG: gme:Gmet_2561 dihydrouridine synthase TIM-barrel protein nifR3; dihydrouridine synthase DuS 2256540..2257484 Kosmotoga olearia TBF 19.5.1 7968536 YP_002941806.1 CDS Kole_2125 NC_012785.1 2257586 2258641 D TIGRFAM: L-threonine 3-dehydrogenase; PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: aba:Acid345_3920 L-threonine 3-dehydrogenase; L-threonine 3-dehydrogenase 2257586..2258641 Kosmotoga olearia TBF 19.5.1 7968537 YP_002941807.1 CDS Kole_2126 NC_012785.1 2258644 2259825 D KEGG: gbm:Gbem_0049 pyridoxal phosphate-dependent acyltransferase; TIGRFAM: pyridoxal phosphate-dependent acyltransferase ; 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class I and II; pyridoxal phosphate-dependent acyltransferase 2258644..2259825 Kosmotoga olearia TBF 19.5.1 7968538 YP_002941808.1 CDS Kole_2127 NC_012785.1 2259892 2260842 D TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region; KEGG: bha:BH0465 hypothetical protein; Na+/Ca+ antiporter, CaCA family 2259892..2260842 Kosmotoga olearia TBF 19.5.1 7968539 YP_002941809.1 CDS Kole_2128 NC_012785.1 2260937 2261389 R PFAM: Rubrerythrin; KEGG: dat:HRM2_23150 Rbr2; Rubrerythrin complement(2260937..2261389) Kosmotoga olearia TBF 19.5.1 7968540 YP_002941810.1 CDS Kole_2129 NC_012785.1 2261838 2262182 D hypothetical protein 2261838..2262182 Kosmotoga olearia TBF 19.5.1 7968541 YP_002941811.1 CDS Kole_2130 NC_012785.1 2262259 2262924 D PFAM: purine or other phosphorylase family 1; KEGG: bha:BH3238 5'-methylthioadenosine/S-adenosylhomocysteine nuclosidase; Adenosylhomocysteine nucleosidase 2262259..2262924 Kosmotoga olearia TBF 19.5.1 7968542 YP_002941812.1 CDS Kole_2131 NC_012785.1 2262952 2263290 D PFAM: histidine triad (HIT) protein; KEGG: tdn:Suden_0868 histidine triad (HIT) protein; histidine triad (HIT) protein 2262952..2263290 Kosmotoga olearia TBF 19.5.1 7968543 YP_002941813.1 CDS Kole_2132 NC_012785.1 2263295 2263909 D PFAM: methyltransferase small; KEGG: baa:BA_0688 hypothetical protein; methyltransferase small 2263295..2263909 Kosmotoga olearia TBF 19.5.1 7968544 YP_002941814.1 CDS Kole_2133 NC_012785.1 2263890 2264600 D PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: baa:BA_0722 ABC transporter; ABC transporter 2263890..2264600 Kosmotoga olearia TBF 19.5.1 7968545 YP_002941815.1 CDS Kole_2134 NC_012785.1 2264618 2265424 D PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: baa:BA_0723 ABC transporter; ABC transporter 2264618..2265424 Kosmotoga olearia TBF 19.5.1 7968546 YP_002941816.1 CDS Kole_2135 NC_012785.1 2265428 2266102 D PFAM: protein of unknown function DUF554; KEGG: dal:Dalk_2095 protein of unknown function DUF554; hypothetical protein 2265428..2266102 Kosmotoga olearia TBF 19.5.1 7968547 YP_002941817.1 CDS Kole_2136 NC_012785.1 2266095 2266946 R TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: dvm:DvMF_0185 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit complement(2266095..2266946) Kosmotoga olearia TBF 19.5.1 7968548 YP_002941818.1 CDS Kole_2137 NC_012785.1 2266943 2268598 R PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: dat:HRM2_41090 PorA2; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein complement(2266943..2268598) Kosmotoga olearia TBF 19.5.1 7968549 YP_002941819.1 CDS Kole_2138 NC_012785.1 2268660 2268821 R PFAM: Rubredoxin-type Fe(Cys)4 protein; KEGG: gsu:GSU3188 rubredoxin; Rubredoxin-type Fe(Cys)4 protein complement(2268660..2268821) Kosmotoga olearia TBF 19.5.1 7968550 YP_002941820.1 CDS Kole_2139 NC_012785.1 2268836 2269192 R PFAM: Desulfoferrodoxin ferrous iron-binding region; KEGG: gme:Gmet_2613 twin-arginine translocation pathway signal; Desulfoferrodoxin ferrous iron-binding region complement(2268836..2269192) Kosmotoga olearia TBF 19.5.1 7968551 YP_002941821.1 CDS Kole_2140 NC_012785.1 2269312 2270151 R PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: dal:Dalk_2742 ribonuclease III; PHP domain protein complement(2269312..2270151) Kosmotoga olearia TBF 19.5.1 7968552 YP_002941822.1 CDS Kole_2141 NC_012785.1 2270363 2271322 D PFAM: phosphoadenosine phosphosulfate reductase; ExsB family protein; KEGG: aba:Acid345_2524 NH(3)-dependent NAD(+) synthetase; phosphoadenosine phosphosulfate reductase 2270363..2271322 Kosmotoga olearia TBF 19.5.1 7968553 YP_002941823.1 CDS Kole_2142 NC_012785.1 2271325 2272167 D TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; Haloacid dehalogenase domain protein hydrolase; sucrose-6F-phosphate phosphohydrolase; KEGG: vfi:VF_A0956 hydrolase; Cof-like hydrolase 2271325..2272167 Kosmotoga olearia TBF 19.5.1 7968554 YP_002941824.1 CDS Kole_2143 NC_012785.1 2272164 2273660 D TIGRFAM: apolipoprotein N-acyltransferase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: aba:Acid345_2341 apolipoprotein N-acyltransferase; apolipoprotein N-acyltransferase 2272164..2273660 Kosmotoga olearia TBF 19.5.1 7968555 YP_002941825.1 CDS Kole_2144 NC_012785.1 2273666 2274448 R PFAM: inositol monophosphatase; KEGG: mxa:MXAN_1914 inositol-1-monophosphatase; inositol monophosphatase complement(2273666..2274448) Kosmotoga olearia TBF 19.5.1 7968556 YP_002941826.1 CDS pheT NC_012785.1 2274441 2276801 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta complement(2274441..2276801) Kosmotoga olearia TBF 19.5.1 7968557 YP_002941827.1 CDS Kole_2146 NC_012785.1 2276798 2277835 R KEGG: glo:Glov_1873 phenylalanyl-tRNA synthetase, alpha subunit; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: phenylalanyl-tRNA synthetase class IIc; aminoacyl tRNA synthetase class II domain protein; phenylalanyl-tRNA synthetase, alpha subunit complement(2276798..2277835) Kosmotoga olearia TBF 19.5.1 7968558 YP_002941828.1 CDS Kole_2147 NC_012785.1 2277868 2278302 R PFAM: ferric-uptake regulator; KEGG: sat:SYN_02524 ferric uptake regulator family protein; ferric uptake regulator, Fur family complement(2277868..2278302) Kosmotoga olearia TBF 19.5.1 7968559 YP_002941829.1 CDS Kole_2148 NC_012785.1 2278401 2279288 R hypothetical protein complement(2278401..2279288) Kosmotoga olearia TBF 19.5.1 7968560 YP_002941830.1 CDS Kole_2149 NC_012785.1 2279304 2279837 R hypothetical protein complement(2279304..2279837) Kosmotoga olearia TBF 19.5.1 7968561 YP_002941831.1 CDS Kole_2150 NC_012785.1 2279830 2280390 R TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: ypg:YpAngola_A3604 RNA polymerase sigma factor RpoE; RNA polymerase, sigma-24 subunit, ECF subfamily complement(2279830..2280390) Kosmotoga olearia TBF 19.5.1 7968562 YP_002941832.1 CDS Kole_2151 NC_012785.1 2280496 2281902 D PFAM: peptidase M18 aminopeptidase I; peptidase M20; KEGG: dat:HRM2_30320 peptidase M18 family protein; peptidase M18 aminopeptidase I 2280496..2281902 Kosmotoga olearia TBF 19.5.1 7968563 YP_002941833.1 CDS Kole_2152 NC_012785.1 2281895 2282527 D KEGG: gsu:GSU1450 endonuclease III, TIGRFAM: endonuclease III; PFAM: HhH-GPD family protein; helix-hairpin-helix motif; SMART: HhH-GPD family protein; iron-sulfur cluster loop; endonuclease III 2281895..2282527 Kosmotoga olearia TBF 19.5.1 7968564 YP_002941834.1 CDS Kole_2153 NC_012785.1 2282481 2284085 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rfr:Rfer_3245 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component complement(2282481..2284085) Kosmotoga olearia TBF 19.5.1 7968565 YP_002941835.1 CDS Kole_2154 NC_012785.1 2284069 2285055 R TIGRFAM: ABC transporter, periplasmic binding protein, thiB subfamily; PFAM: extracellular solute-binding protein family 1; KEGG: avi:Avi_4266 ABC transporter substrate binding protein (thiamine); ABC transporter substrate-binding protein complement(2284069..2285055) Kosmotoga olearia TBF 19.5.1 7968566 YP_002941836.1 CDS Kole_2155 NC_012785.1 2285275 2288331 D KEGG: bsu:BSU00550 transcription-repair coupling factor; TIGRFAM: transcription-repair coupling factor; PFAM: DEAD/DEAH box helicase domain protein; transcription factor CarD; helicase domain protein; TRCF domain protein; SMART: DEAD-like helicase ; helicase domain protein; transcription-repair coupling factor 2285275..2288331 Kosmotoga olearia TBF 19.5.1 7968567 YP_002941837.1 CDS Kole_2156 NC_012785.1 2288321 2289643 D TIGRFAM: tRNA modification GTPase TrmE; small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; Miro domain protein; KEGG: nam:NAMH_0844 tRNA modification GTPase TrmE; tRNA modification GTPase TrmE 2288321..2289643 Kosmotoga olearia TBF 19.5.1 7968568 YP_002941838.1 CDS Kole_2157 NC_012785.1 2289652 2290356 D hypothetical protein 2289652..2290356 Kosmotoga olearia TBF 19.5.1 7968569 YP_002941839.1 CDS Kole_2158 NC_012785.1 2290390 2290932 R TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: dvl:Dvul_0047 pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate/ketoisovalerate oxidoreductase, gamma subunit complement(2290390..2290932) Kosmotoga olearia TBF 19.5.1 7968570 YP_002941840.1 CDS Kole_2159 NC_012785.1 2290929 2291684 R PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: sfu:Sfum_0300 thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate protein domain protein TPP-binding complement(2290929..2291684) Kosmotoga olearia TBF 19.5.1 7968571 YP_002941841.1 CDS Kole_2160 NC_012785.1 2291687 2292754 R catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA; 2-ketoisovalerate ferredoxin reductase complement(2291687..2292754) Kosmotoga olearia TBF 19.5.1 7968572 YP_002941842.1 CDS Kole_2161 NC_012785.1 2292768 2292998 R PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: glo:Glov_2310 4Fe-4S ferredoxin iron-sulfur binding domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein complement(2292768..2292998) Kosmotoga olearia TBF 19.5.1 7968573 YP_002941843.1 CDS Kole_2162 NC_012785.1 2293000 2293677 R KEGG: dat:HRM2_10670 hypothetical protein; hypothetical protein complement(2293000..2293677) Kosmotoga olearia TBF 19.5.1 7968574 YP_002941844.1 CDS Kole_2163 NC_012785.1 2293655 2294746 R catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; butyrate kinase complement(2293655..2294746) Kosmotoga olearia TBF 19.5.1 7968575 YP_002941845.1 CDS Kole_2164 NC_012785.1 2294749 2295651 R PFAM: phosphate acetyl/butaryl transferase; KEGG: baa:BA_4843 PTA_PTB, phosphate acetyl/butaryl transferase; Phosphate butyryltransferase complement(2294749..2295651) Kosmotoga olearia TBF 19.5.1 7968576 YP_002941846.1 CDS Kole_2165 NC_012785.1 2295648 2296718 R catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; butyrate kinase complement(2295648..2296718) Kosmotoga olearia TBF 19.5.1 7968577 YP_002941847.1 CDS Kole_2166 NC_012785.1 2296730 2297962 R PFAM: aminotransferase class I and II; KEGG: bpt:Bpet4860 aminotransferase; GntR family transcriptional regulator complement(2296730..2297962) Kosmotoga olearia TBF 19.5.1 7968578 YP_002941848.1 CDS Kole_2167 NC_012785.1 2298306 2299676 D PFAM: Citrate transporter; Arsenical pump membrane protein; KEGG: baa:BA_0017 arsenical pump membrane protein; Citrate transporter 2298306..2299676 Kosmotoga olearia TBF 19.5.1 7968579 YP_002941849.1 CDS Kole_2168 NC_012785.1 2299690 2300832 D PFAM: aminotransferase class V; KEGG: sus:Acid_1660 phosphoserine aminotransferase / L-aspartate aminotransferase; aminotransferase class V 2299690..2300832 Kosmotoga olearia TBF 19.5.1 7968580 YP_002941850.1 CDS Kole_2169 NC_012785.1 2300832 2301755 D PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: afw:Anae109_2506 D-3-phosphoglycerate dehydrogenase; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding 2300832..2301755 Kosmotoga olearia TBF 19.5.1 7968581 YP_002941851.1 CDS Kole_2170 NC_012785.1 2301792 2301971 D PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dvu:DVU0305 ferredoxin II; 4Fe-4S ferredoxin iron-sulfur binding domain protein 2301792..2301971 Kosmotoga olearia TBF 19.5.1 7968582 Kole_R0001 tRNA Kole_R0001 NC_012785.1 48490 48565 D tRNA-Glu 48490..48565 Kosmotoga olearia TBF 19.5.1 7968867 Kole_R0002 tRNA Kole_R0002 NC_012785.1 48571 48645 D tRNA-Val 48571..48645 Kosmotoga olearia TBF 19.5.1 7968868 Kole_R0003 tRNA Kole_R0003 NC_012785.1 48654 48729 D tRNA-Phe 48654..48729 Kosmotoga olearia TBF 19.5.1 7968869 Kole_R0004 tRNA Kole_R0004 NC_012785.1 52605 52680 D tRNA-Ala 52605..52680 Kosmotoga olearia TBF 19.5.1 7968874 Kole_R0005 tRNA Kole_R0005 NC_012785.1 56969 57059 D tRNA-Ser 56969..57059 Kosmotoga olearia TBF 19.5.1 7968877 Kole_R0007 tRNA Kole_R0007 NC_012785.1 136825 136900 R tRNA-Pro complement(136825..136900) Kosmotoga olearia TBF 19.5.1 7967539 Kole_R0008 tRNA Kole_R0008 NC_012785.1 143563 143650 R tRNA-Leu complement(143563..143650) Kosmotoga olearia TBF 19.5.1 7967547 Kole_R0009 tRNA Kole_R0009 NC_012785.1 173631 173705 R tRNA-Asn complement(173631..173705) Kosmotoga olearia TBF 19.5.1 7968308 Kole_R0011 tRNA Kole_R0011 NC_012785.1 355929 356004 D tRNA-Pro 355929..356004 Kosmotoga olearia TBF 19.5.1 7968927 Kole_R0012 tRNA Kole_R0012 NC_012785.1 356010 356085 D tRNA-Gly 356010..356085 Kosmotoga olearia TBF 19.5.1 7968928 Kole_R0013 tRNA Kole_R0013 NC_012785.1 356086 356161 D tRNA-Arg 356086..356161 Kosmotoga olearia TBF 19.5.1 7968929 Kole_R0014 tRNA Kole_R0014 NC_012785.1 356180 356255 D tRNA-His 356180..356255 Kosmotoga olearia TBF 19.5.1 7968930 Kole_R0015 tRNA Kole_R0015 NC_012785.1 356266 356342 D tRNA-Arg 356266..356342 Kosmotoga olearia TBF 19.5.1 7968931 Kole_R0016 tRNA Kole_R0016 NC_012785.1 358746 358833 R tRNA-Ser complement(358746..358833) Kosmotoga olearia TBF 19.5.1 7968934 Kole_R0017 tRNA Kole_R0017 NC_012785.1 402469 402544 R tRNA-Gln complement(402469..402544) Kosmotoga olearia TBF 19.5.1 7968981 Kole_R0018 tRNA Kole_R0018 NC_012785.1 598025 598101 R tRNA-Arg complement(598025..598101) Kosmotoga olearia TBF 19.5.1 7967408 Kole_R0019 tRNA Kole_R0019 NC_012785.1 598109 598198 R tRNA-Ser complement(598109..598198) Kosmotoga olearia TBF 19.5.1 7967409 Kole_R0020 tRNA Kole_R0020 NC_012785.1 795650 795724 R tRNA-Val complement(795650..795724) Kosmotoga olearia TBF 19.5.1 7969343 Kole_R0021 tRNA Kole_R0021 NC_012785.1 799040 799127 D tRNA-Leu 799040..799127 Kosmotoga olearia TBF 19.5.1 7969349 Kole_R0022 tRNA Kole_R0022 NC_012785.1 802400 802473 R tRNA-Gln complement(802400..802473) Kosmotoga olearia TBF 19.5.1 7969352 Kole_R0023 tRNA Kole_R0023 NC_012785.1 1055035 1055110 R tRNA-Pro complement(1055035..1055110) Kosmotoga olearia TBF 19.5.1 7967701 Kole_R0027 tRNA Kole_R0027 NC_012785.1 1220162 1220238 R tRNA-Cys complement(1220162..1220238) Kosmotoga olearia TBF 19.5.1 7967941 Kole_R0028 tRNA Kole_R0028 NC_012785.1 1220932 1221008 D tRNA-Asp 1220932..1221008 Kosmotoga olearia TBF 19.5.1 7967942 Kole_R0029 tRNA Kole_R0029 NC_012785.1 1489123 1489200 D tRNA-Met 1489123..1489200 Kosmotoga olearia TBF 19.5.1 7968710 Kole_R0030 tRNA Kole_R0030 NC_012785.1 1493168 1493242 D tRNA-Arg 1493168..1493242 Kosmotoga olearia TBF 19.5.1 7968715 Kole_R0031 tRNA Kole_R0031 NC_012785.1 1503452 1503528 R tRNA-Met complement(1503452..1503528) Kosmotoga olearia TBF 19.5.1 7968725 Kole_R0032 tRNA Kole_R0032 NC_012785.1 1503539 1503615 R tRNA-Met complement(1503539..1503615) Kosmotoga olearia TBF 19.5.1 7968726 Kole_R0033 tRNA Kole_R0033 NC_012785.1 1503661 1503749 R tRNA-Leu complement(1503661..1503749) Kosmotoga olearia TBF 19.5.1 7968727 Kole_R0034 tRNA Kole_R0034 NC_012785.1 1548378 1548453 D tRNA-Lys 1548378..1548453 Kosmotoga olearia TBF 19.5.1 7969090 Kole_R0035 tRNA Kole_R0035 NC_012785.1 1566428 1566516 R tRNA-Ser complement(1566428..1566516) Kosmotoga olearia TBF 19.5.1 7969110 Kole_R0036 tRNA Kole_R0036 NC_012785.1 1583765 1583840 D tRNA-Arg 1583765..1583840 Kosmotoga olearia TBF 19.5.1 7969127 Kole_R0037 tRNA Kole_R0037 NC_012785.1 1678676 1678751 D tRNA-Thr 1678676..1678751 Kosmotoga olearia TBF 19.5.1 7968644 Kole_R0038 tRNA Kole_R0038 NC_012785.1 1730041 1730116 D tRNA-Ala 1730041..1730116 Kosmotoga olearia TBF 19.5.1 7967845 Kole_R0039 tRNA Kole_R0039 NC_012785.1 1737890 1737966 R tRNA-Thr complement(1737890..1737966) Kosmotoga olearia TBF 19.5.1 7967852 Kole_R0041 tRNA Kole_R0041 NC_012785.1 1772115 1772191 D tRNA-Ile 1772115..1772191 Kosmotoga olearia TBF 19.5.1 7967883 Kole_R0042 tRNA Kole_R0042 NC_012785.1 1772196 1772271 D tRNA-Ala 1772196..1772271 Kosmotoga olearia TBF 19.5.1 7967884 Kole_R0045 tRNA Kole_R0045 NC_012785.1 1842123 1842197 R tRNA-Val complement(1842123..1842197) Kosmotoga olearia TBF 19.5.1 7968113 Kole_R0046 tRNA Kole_R0046 NC_012785.1 1879441 1879515 R tRNA-Gly complement(1879441..1879515) Kosmotoga olearia TBF 19.5.1 7968232 Kole_R0047 tRNA Kole_R0047 NC_012785.1 1879553 1879641 R tRNA-Leu complement(1879553..1879641) Kosmotoga olearia TBF 19.5.1 7968233 Kole_R0048 tRNA Kole_R0048 NC_012785.1 1879642 1879717 R tRNA-Lys complement(1879642..1879717) Kosmotoga olearia TBF 19.5.1 7968234 Kole_R0050 tRNA Kole_R0050 NC_012785.1 1949627 1949702 R tRNA-Trp complement(1949627..1949702) Kosmotoga olearia TBF 19.5.1 7967742 Kole_R0051 tRNA Kole_R0051 NC_012785.1 1978158 1978244 R tRNA-Tyr complement(1978158..1978244) Kosmotoga olearia TBF 19.5.1 7967766 Kole_R0052 tRNA Kole_R0052 NC_012785.1 1978258 1978333 R tRNA-Thr complement(1978258..1978333) Kosmotoga olearia TBF 19.5.1 7967767 Kole_R0053 tRNA Kole_R0053 NC_012785.1 2162866 2162941 R tRNA-Gly complement(2162866..2162941) Kosmotoga olearia TBF 19.5.1 7967634 Kole_R0054 tRNA Kole_R0054 NC_012785.1 2174826 2174915 R tRNA-Leu complement(2174826..2174915) Kosmotoga olearia TBF 19.5.1 7967645 Kole_R0055 tRNA Kole_R0055 NC_012785.1 2229643 2229717 R tRNA-Glu complement(2229643..2229717) Kosmotoga olearia TBF 19.5.1 7968511 Kole_R0024 rRNA Kole_R0024 NC_012785.1 1206136 1207662 D 16S ribosomal RNA 1206136..1207662 Kosmotoga olearia TBF 19.5.1 7967926 Kole_R0025 rRNA Kole_R0025 NC_012785.1 1207740 1210691 D 23S ribosomal RNA 1207740..1210691 Kosmotoga olearia TBF 19.5.1 7967927 Kole_R0026 rRNA Kole_R0026 NC_012785.1 1210728 1210844 D 5S ribosomal RNA 1210728..1210844 Kosmotoga olearia TBF 19.5.1 7967928 Kole_R0040 rRNA Kole_R0040 NC_012785.1 1770534 1772060 D 16S ribosomal RNA 1770534..1772060 Kosmotoga olearia TBF 19.5.1 7967882 Kole_R0043 rRNA Kole_R0043 NC_012785.1 1772313 1775264 D 23S ribosomal RNA 1772313..1775264 Kosmotoga olearia TBF 19.5.1 7967885 Kole_R0044 rRNA Kole_R0044 NC_012785.1 1775301 1775417 D 5S ribosomal RNA 1775301..1775417 Kosmotoga olearia TBF 19.5.1 7967886