-- dump date 20140619_122349 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_192940.1 58336355 3252574 31..1398 1 NC_006814.3 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 1398 dnaA 3252574 dnaA Lactobacillus acidophilus NCFM chromosomal replication initiation protein YP_192940.1 31 D 272621 CDS YP_192941.1 58336356 3252571 1576..2706 1 NC_006814.3 DNA polymerase III subunit beta 2706 dnaN 3252571 dnaN Lactobacillus acidophilus NCFM DNA polymerase III subunit beta YP_192941.1 1576 D 272621 CDS YP_192942.1 58336357 3252664 2925..3155 1 NC_006814.3 COG2501 Uncharacterized conserved protein; hypothetical protein 3155 3252664 LBA0003 Lactobacillus acidophilus NCFM hypothetical protein YP_192942.1 2925 D 272621 CDS YP_192943.1 58336358 3252300 3155..4282 1 NC_006814.3 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 4282 recF 3252300 recF Lactobacillus acidophilus NCFM recombination protein F YP_192943.1 3155 D 272621 CDS YP_192944.1 58336359 3252055 4283..6247 1 NC_006814.3 DNA gyrase subunit B 6247 gyrB 3252055 gyrB Lactobacillus acidophilus NCFM DNA gyrase subunit B YP_192944.1 4283 D 272621 CDS YP_192945.1 58336360 3252401 6258..8732 1 NC_006814.3 DNA gyrase subunit A 8732 gyrA 3252401 gyrA Lactobacillus acidophilus NCFM DNA gyrase subunit A YP_192945.1 6258 D 272621 CDS YP_192946.1 58336361 3252918 8933..9229 1 NC_006814.3 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 9229 rpsF 3252918 rpsF Lactobacillus acidophilus NCFM 30S ribosomal protein S6 YP_192946.1 8933 D 272621 CDS YP_192947.1 58336362 3252118 9275..9793 1 NC_006814.3 COG0629 Single-stranded DNA-binding protein; single-stranded DNA-binding protein 9793 3252118 LBA0008 Lactobacillus acidophilus NCFM single-stranded DNA-binding protein YP_192947.1 9275 D 272621 CDS YP_192948.1 58336363 3252908 9822..10058 1 NC_006814.3 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 10058 rpsR 3252908 rpsR Lactobacillus acidophilus NCFM 30S ribosomal protein S18 YP_192948.1 9822 D 272621 CDS YP_192949.1 58336364 3252791 10237..12258 1 NC_006814.3 signaling protein 12258 3252791 LBA0011 Lactobacillus acidophilus NCFM signaling protein YP_192949.1 10237 D 272621 CDS YP_192950.1 58336365 3253111 12271..12726 1 NC_006814.3 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 12726 rplI 3253111 rplI Lactobacillus acidophilus NCFM 50S ribosomal protein L9 YP_192950.1 12271 D 272621 CDS YP_192951.1 58336366 3252785 12752..14146 1 NC_006814.3 COG0305 Replicative DNA helicase; replicative DNA helicase 14146 dnaB 3252785 dnaB Lactobacillus acidophilus NCFM replicative DNA helicase YP_192951.1 12752 D 272621 CDS YP_192952.1 58336367 3252865 14388..15329 1 NC_006814.3 alkylphosphonate ABC transporter 15329 3252865 LBA0014 Lactobacillus acidophilus NCFM alkylphosphonate ABC transporter YP_192952.1 14388 D 272621 CDS YP_192953.1 58336368 3252763 15433..16362 1 NC_006814.3 hypothetical protein 16362 3252763 LBA0015 Lactobacillus acidophilus NCFM hypothetical protein YP_192953.1 15433 D 272621 CDS YP_192954.1 58336369 3252120 16483..17361 1 NC_006814.3 COG1940 transcriptional regulator-sugar kinase; fructokinase 17361 3252120 LBA0016 Lactobacillus acidophilus NCFM fructokinase YP_192954.1 16483 D 272621 CDS YP_192955.1 58336370 3252563 17507..17695 1 NC_006814.3 COG3237 Uncharacterized protein conserved in bacteria; general stress response 17695 3252563 LBA0017 Lactobacillus acidophilus NCFM general stress response YP_192955.1 17507 D 272621 CDS YP_192956.3 596444058 3252210 complement(17752..18036) 1 NC_006814.3 membrane protein 18036 3252210 LBA0018 Lactobacillus acidophilus NCFM membrane protein YP_192956.3 17752 R 272621 CDS YP_192957.1 58336372 3252562 complement(18057..19283) 1 NC_006814.3 hypothetical protein 19283 3252562 LBA0019 Lactobacillus acidophilus NCFM hypothetical protein YP_192957.1 18057 R 272621 CDS YP_192958.1 58336373 3252806 19827..20474 1 NC_006814.3 CadD; cadmium resistance protein 20474 cadB 3252806 cadB Lactobacillus acidophilus NCFM cadmium resistance protein YP_192958.1 19827 D 272621 CDS YP_192959.1 58336374 3252138 20491..20844 1 NC_006814.3 cadmium resistance regulatory protein 20844 cadX 3252138 cadX Lactobacillus acidophilus NCFM cadmium resistance regulatory protein YP_192959.1 20491 D 272621 CDS YP_192960.1 58336375 3252838 complement(21324..22274) 1 NC_006814.3 NAD-dependent malic enzyme (malate oxidoreductase); hypothetical protein 22274 3252838 LBA0023 Lactobacillus acidophilus NCFM hypothetical protein YP_192960.1 21324 R 272621 CDS YP_192961.1 58336376 3252957 22411..22722 1 NC_006814.3 hypothetical protein 22722 3252957 LBA0024 Lactobacillus acidophilus NCFM hypothetical protein YP_192961.1 22411 D 272621 CDS YP_192962.1 58336377 3252740 22722..23798 1 NC_006814.3 FtsK; hypothetical protein; cell division protein 23798 ftsK 3252740 ftsK Lactobacillus acidophilus NCFM cell division protein YP_192962.1 22722 D 272621 CDS YP_192963.1 58336378 3252579 23795..24325 1 NC_006814.3 hypothetical protein 24325 3252579 LBA0026 Lactobacillus acidophilus NCFM hypothetical protein YP_192963.1 23795 D 272621 CDS YP_192964.1 58336379 3252985 24511..25452 1 NC_006814.3 replication initiator protein 25452 repB 3252985 repB Lactobacillus acidophilus NCFM replication initiator protein YP_192964.1 24511 D 272621 CDS YP_192965.1 58336380 3252460 25673..25864 1 NC_006814.3 VrlI protein; hypothetical protein 25864 3252460 LBA0028 Lactobacillus acidophilus NCFM hypothetical protein YP_192965.1 25673 D 272621 CDS YP_192966.1 58336381 3252861 25928..27163 1 NC_006814.3 hypothetical protein Ljo_1749; integrase 27163 3252861 LBA0029 Lactobacillus acidophilus NCFM integrase YP_192966.1 25928 D 272621 CDS YP_192967.1 58336382 3252302 27424..27639 1 NC_006814.3 COG1912 Uncharacterized conserved protein; hypothetical protein 27639 3252302 LBA0030 Lactobacillus acidophilus NCFM hypothetical protein YP_192967.1 27424 D 272621 CDS YP_192968.1 58336383 3252904 27643..28044 1 NC_006814.3 hypothetical protein 28044 3252904 LBA0031 Lactobacillus acidophilus NCFM hypothetical protein YP_192968.1 27643 D 272621 CDS YP_192969.1 58336384 3252558 28644..28952 1 NC_006814.3 hypothetical protein 28952 3252558 LBA0032 Lactobacillus acidophilus NCFM hypothetical protein YP_192969.1 28644 D 272621 CDS YP_192970.1 58336385 3253025 complement(29358..30182) 1 NC_006814.3 COG2746 Aminoglycoside N3'-acetyltransferase; aminoglycoside N3-acetyltransferase 30182 3253025 LBA0034 Lactobacillus acidophilus NCFM aminoglycoside N3-acetyltransferase YP_192970.1 29358 R 272621 CDS YP_192971.1 58336386 3252280 30348..31748 1 NC_006814.3 cytosol non-specific dipeptidase 31748 3252280 LBA0035 Lactobacillus acidophilus NCFM cytosol non-specific dipeptidase YP_192971.1 30348 D 272621 CDS YP_192972.1 58336387 3252273 31916..33223 1 NC_006814.3 collagen-binding protein Cne precursor; hypothetical protein 33223 3252273 LBA0036 Lactobacillus acidophilus NCFM hypothetical protein YP_192972.1 31916 D 272621 CDS YP_192973.1 58336388 3252141 33320..34117 1 NC_006814.3 COG4905 Predicted membrane protein; hypothetical protein 34117 3252141 LBA0037 Lactobacillus acidophilus NCFM hypothetical protein YP_192973.1 33320 D 272621 CDS YP_192974.1 58336389 3252897 complement(34136..34699) 1 NC_006814.3 COG2096 Uncharacterized conserved protein; cobalamin adenosyltransferase 34699 3252897 LBA0038 Lactobacillus acidophilus NCFM cobalamin adenosyltransferase YP_192974.1 34136 R 272621 CDS YP_192975.1 58336390 3252277 complement(34699..35223) 1 NC_006814.3 hypothetical protein 35223 3252277 LBA0039 Lactobacillus acidophilus NCFM hypothetical protein YP_192975.1 34699 R 272621 CDS YP_192977.1 58336392 3252771 complement(35642..37876) 1 NC_006814.3 ribonucleoside triphosphate reductase 37876 3252771 LBA0041 Lactobacillus acidophilus NCFM ribonucleoside triphosphate reductase YP_192977.1 35642 R 272621 CDS YP_192978.1 58336393 3252790 38124..39164 1 NC_006814.3 COG0628 Predicted permease; permease 39164 3252790 LBA0043 Lactobacillus acidophilus NCFM permease YP_192978.1 38124 D 272621 CDS YP_192979.1 58336394 3252888 39161..39733 1 NC_006814.3 esterase 39733 3252888 LBA0044 Lactobacillus acidophilus NCFM esterase YP_192979.1 39161 D 272621 CDS YP_192980.1 58336395 3252772 40163..41515 1 NC_006814.3 sugar transporter 41515 3252772 LBA0045 Lactobacillus acidophilus NCFM sugar transporter YP_192980.1 40163 D 272621 CDS YP_192981.1 58336396 3252550 complement(41634..41990) 1 NC_006814.3 isoleucyl-tRNA synthetase; hypothetical protein 41990 3252550 LBA0046 Lactobacillus acidophilus NCFM hypothetical protein YP_192981.1 41634 R 272621 CDS YP_192982.1 58336397 3252135 complement(42202..42963) 1 NC_006814.3 ABC transporter ATP-binding protein 42963 3252135 LBA0047 Lactobacillus acidophilus NCFM ABC transporter ATP-binding protein YP_192982.1 42202 R 272621 CDS YP_192983.1 58336398 3252849 complement(42960..43856) 1 NC_006814.3 ABC transporter membrane spanning permease 43856 3252849 LBA0048 Lactobacillus acidophilus NCFM ABC transporter membrane spanning permease YP_192983.1 42960 R 272621 CDS YP_192984.1 58336399 3252436 complement(43853..44845) 1 NC_006814.3 ABC transporter substrate binding protein 44845 3252436 LBA0049 Lactobacillus acidophilus NCFM ABC transporter substrate binding protein YP_192984.1 43853 R 272621 CDS YP_192985.1 58336400 3252503 45194..45907 1 NC_006814.3 hydrolase 45907 3252503 LBA0050 Lactobacillus acidophilus NCFM hydrolase YP_192985.1 45194 D 272621 CDS YP_192986.1 58336401 3252464 45976..47895 1 NC_006814.3 GTPase; translation elongation factors 47895 3252464 LBA0051 Lactobacillus acidophilus NCFM translation elongation factors YP_192986.1 45976 D 272621 CDS YP_192987.1 58336402 3252130 48016..48834 1 NC_006814.3 hydrolase 48834 3252130 LBA0052 Lactobacillus acidophilus NCFM hydrolase YP_192987.1 48016 D 272621 CDS YP_192988.1 58336403 3252898 complement(48869..49087) 1 NC_006814.3 hypothetical protein 49087 3252898 LBA0053 Lactobacillus acidophilus NCFM hypothetical protein YP_192988.1 48869 R 272621 CDS YP_192989.1 58336404 3252147 complement(49012..49725) 1 NC_006814.3 Endonuclease-Exonuclease-phosphatase; endonuclease-exonuclease-phosphatase 49725 3252147 LBA0054 Lactobacillus acidophilus NCFM endonuclease-exonuclease-phosphatase YP_192989.1 49012 R 272621 CDS YP_192990.1 58336405 3252750 complement(50079..51128) 1 NC_006814.3 D-lactate dehydrogenase 51128 ldhD 3252750 ldhD Lactobacillus acidophilus NCFM D-lactate dehydrogenase YP_192990.1 50079 R 272621 CDS YP_192991.1 58336406 3252049 51696..52523 1 NC_006814.3 COG0708 Exonuclease III; exodeoxyribonuclease A 52523 exoA 3252049 exoA Lactobacillus acidophilus NCFM exodeoxyribonuclease A YP_192991.1 51696 D 272621 CDS YP_192992.1 58336407 3252754 52583..54025 1 NC_006814.3 GadC; COG0531 Amino acid transporters; glutamategamma-aminobutyrate antiporter 54025 gadC 3252754 gadC Lactobacillus acidophilus NCFM glutamategamma-aminobutyrate antiporter YP_192992.1 52583 D 272621 CDS YP_192993.1 58336408 3252275 54086..56920 1 NC_006814.3 phage DEAD box family helicase 56920 3252275 LBA0058 Lactobacillus acidophilus NCFM phage DEAD box family helicase YP_192993.1 54086 D 272621 CDS YP_192994.1 58336409 3252674 complement(56949..58073) 1 NC_006814.3 PbpX; penicillin-binding protein 58073 pbpX 3252674 pbpX Lactobacillus acidophilus NCFM penicillin-binding protein YP_192994.1 56949 R 272621 CDS YP_192995.1 58336410 3252932 58261..58674 1 NC_006814.3 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 58674 3252932 LBA0060 Lactobacillus acidophilus NCFM peptide deformylase YP_192995.1 58261 D 272621 CDS YP_192996.1 58336411 3252936 65297..65641 1 NC_006814.3 hypothetical protein 65641 3252936 LBA0062 Lactobacillus acidophilus NCFM hypothetical protein YP_192996.1 65297 D 272621 CDS YP_192997.1 58336412 3252809 65668..65790 1 NC_006814.3 fumarate reductase flavoprotein subunit 65790 3252809 LBA0063 Lactobacillus acidophilus NCFM fumarate reductase flavoprotein subunit YP_192997.1 65668 D 272621 CDS YP_192998.1 58336413 3252948 65956..67146 1 NC_006814.3 fumarate reductase flavoprotein subunit 67146 3252948 LBA0064 Lactobacillus acidophilus NCFM fumarate reductase flavoprotein subunit YP_192998.1 65956 D 272621 CDS YP_192999.1 58336414 3252157 complement(67176..67817) 1 NC_006814.3 transcriptional regulator 67817 lysR 3252157 lysR Lactobacillus acidophilus NCFM transcriptional regulator YP_192999.1 67176 R 272621 CDS YP_193000.1 58336415 3252974 complement(67978..68208) 1 NC_006814.3 steroid binding protein 68208 3252974 LBA0066 Lactobacillus acidophilus NCFM steroid binding protein YP_193000.1 67978 R 272621 CDS YP_193001.1 58336416 3252920 complement(68304..69173) 1 NC_006814.3 phospho-beta-glycosidase 69173 arbZ 3252920 arbZ Lactobacillus acidophilus NCFM phospho-beta-glycosidase YP_193001.1 68304 R 272621 CDS YP_193002.1 58336417 3253018 complement(69170..70117) 1 NC_006814.3 potential frameshift to 69; glycosyl transferase family protein 70117 3253018 LBA0068 Lactobacillus acidophilus NCFM glycosyl transferase family protein YP_193002.1 69170 R 272621 CDS YP_193003.1 58336418 3252981 complement(70130..71086) 1 NC_006814.3 potential frameshift to 68; glucosyl transferase 71086 3252981 LBA0069 Lactobacillus acidophilus NCFM glucosyl transferase YP_193003.1 70130 R 272621 CDS YP_193004.1 58336419 3252885 complement(71116..71952) 1 NC_006814.3 glycosyl transferase family protein 71952 arbx 3252885 arbx Lactobacillus acidophilus NCFM glycosyl transferase family protein YP_193004.1 71116 R 272621 CDS YP_193005.1 58336420 3252152 complement(72186..72278) 1 NC_006814.3 hypothetical protein 72278 3252152 LBA0071 Lactobacillus acidophilus NCFM hypothetical protein YP_193005.1 72186 R 272621 CDS YP_193006.1 58336421 3252658 complement(72596..73354) 1 NC_006814.3 hypothetical protein 73354 3252658 LBA0072 Lactobacillus acidophilus NCFM hypothetical protein YP_193006.1 72596 R 272621 CDS YP_193007.1 58336422 3252964 73477..73941 1 NC_006814.3 OSJNBa0035I04.2; hypothetical protein 73941 3252964 LBA0073 Lactobacillus acidophilus NCFM hypothetical protein YP_193007.1 73477 D 272621 CDS YP_193008.1 58336423 3252925 74379..75971 1 NC_006814.3 ABC transporter bacteriocin 75971 3252925 LBA0074 Lactobacillus acidophilus NCFM ABC transporter bacteriocin YP_193008.1 74379 D 272621 CDS YP_193009.1 58336424 3252642 75973..77565 1 NC_006814.3 ABC transporter bacteriocin 77565 3252642 LBA0075 Lactobacillus acidophilus NCFM ABC transporter bacteriocin YP_193009.1 75973 D 272621 CDS YP_193010.1 58336425 3252810 complement(77542..79248) 1 NC_006814.3 transposase 79248 3252810 LBA0077 Lactobacillus acidophilus NCFM transposase YP_193010.1 77542 R 272621 CDS YP_193011.1 58336426 3252835 79913..80629 1 NC_006814.3 VicR; COG0745 Response regulators conserved isting of a CheY-like receiver domain and a winged-helix DNA-binding domain; response regulator 80629 3252835 LBA0078 Lactobacillus acidophilus NCFM response regulator YP_193011.1 79913 D 272621 CDS YP_193012.1 58336427 3252854 80698..82554 1 NC_006814.3 VicK; histidine kinase 82554 3252854 LBA0079 Lactobacillus acidophilus NCFM histidine kinase YP_193012.1 80698 D 272621 CDS YP_193013.1 58336428 3252866 82535..83893 1 NC_006814.3 hypothetical protein 83893 yycH 3252866 yycH Lactobacillus acidophilus NCFM hypothetical protein YP_193013.1 82535 D 272621 CDS YP_193014.1 58336429 3252219 83894..84718 1 NC_006814.3 hypothetical protein 84718 yycI 3252219 yycI Lactobacillus acidophilus NCFM hypothetical protein YP_193014.1 83894 D 272621 CDS YP_193015.1 58336430 3252993 84727..85524 1 NC_006814.3 hypothetical protein 85524 3252993 LBA0082 Lactobacillus acidophilus NCFM hypothetical protein YP_193015.1 84727 D 272621 CDS YP_193016.1 58336431 3252346 85570..86841 1 NC_006814.3 HtrA; Serine protease do-like HtrA; heat shock related serine protease 86841 htrA 3252346 htrA Lactobacillus acidophilus NCFM heat shock related serine protease YP_193016.1 85570 D 272621 CDS YP_193017.1 58336432 3252357 87312..87791 1 NC_006814.3 SPOUT methyltransferase; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 87791 3252357 LBA0084 Lactobacillus acidophilus NCFM rRNA large subunit methyltransferase YP_193017.1 87312 D 272621 CDS YP_193018.1 58336433 3252367 87843..88658 1 NC_006814.3 COG1396 Predicted transcriptional regulators; transcriptional regulator 88658 3252367 LBA0085 Lactobacillus acidophilus NCFM transcriptional regulator YP_193018.1 87843 D 272621 CDS YP_193019.1 58336434 3252373 88840..89115 1 NC_006814.3 membrane protein; hypothetical protein 89115 3252373 LBA0086 Lactobacillus acidophilus NCFM hypothetical protein YP_193019.1 88840 D 272621 CDS YP_193020.1 58336435 3252386 89158..90615 1 NC_006814.3 protease 90615 3252386 LBA0087 Lactobacillus acidophilus NCFM protease YP_193020.1 89158 D 272621 CDS YP_193021.1 58336436 3252393 90778..90882 1 NC_006814.3 hypothetical protein 90882 3252393 LBA0088 Lactobacillus acidophilus NCFM hypothetical protein YP_193021.1 90778 D 272621 CDS YP_193022.1 58336437 3252394 90994..91185 1 NC_006814.3 hypothetical protein 91185 3252394 LBA0089 Lactobacillus acidophilus NCFM hypothetical protein YP_193022.1 90994 D 272621 CDS YP_193023.1 58336438 3252417 91251..91940 1 NC_006814.3 hypothetical protein 91940 3252417 LBA0091 Lactobacillus acidophilus NCFM hypothetical protein YP_193023.1 91251 D 272621 CDS YP_193024.1 58336439 3252419 complement(91987..92868) 1 NC_006814.3 Proline iminopeptidase (PIP) (Prolyl aminopeptidase) (PAP); prolyl aminopeptidase 92868 3252419 LBA0092 Lactobacillus acidophilus NCFM prolyl aminopeptidase YP_193024.1 91987 R 272621 CDS YP_193025.1 58336440 3252427 complement(92877..93530) 1 NC_006814.3 ABC transporter permease 93530 3252427 LBA0093 Lactobacillus acidophilus NCFM ABC transporter permease YP_193025.1 92877 R 272621 CDS YP_193026.1 58336441 3252429 complement(93533..94882) 1 NC_006814.3 Binding; COG1122 ABC-type cobalt transport system ATPase component; ABC transporter ATP-binding protein 94882 3252429 LBA0094 Lactobacillus acidophilus NCFM ABC transporter ATP-binding protein YP_193026.1 93533 R 272621 CDS YP_193027.1 58336442 3252453 95028..95969 1 NC_006814.3 regulatory protein 95969 3252453 LBA0095 Lactobacillus acidophilus NCFM regulatory protein YP_193027.1 95028 D 272621 CDS YP_193028.1 58336443 3252455 complement(96007..96903) 1 NC_006814.3 metalloprotease; heat shock protein HtpX 96903 htpX 3252455 htpX Lactobacillus acidophilus NCFM heat shock protein HtpX YP_193028.1 96007 R 272621 CDS YP_193029.1 58336444 3252474 complement(96920..97480) 1 NC_006814.3 LemA; COG1704 Uncharacterized conserved protein; hypothetical protein 97480 lemA 3252474 lemA Lactobacillus acidophilus NCFM hypothetical protein YP_193029.1 96920 R 272621 CDS YP_193030.1 58336445 3252488 complement(97579..98685) 1 NC_006814.3 cation transporter 98685 3252488 LBA0098 Lactobacillus acidophilus NCFM cation transporter YP_193030.1 97579 R 272621 CDS YP_193031.1 58336446 3252500 98749..98841 1 NC_006814.3 hypothetical protein 98841 3252500 LBA0099 Lactobacillus acidophilus NCFM hypothetical protein YP_193031.1 98749 D 272621 CDS YP_193032.1 58336447 3252505 98869..99276 1 NC_006814.3 hypothetical protein 99276 3252505 LBA0100 Lactobacillus acidophilus NCFM hypothetical protein YP_193032.1 98869 D 272621 CDS YP_193033.1 58336448 3252515 99286..101043 1 NC_006814.3 glycerophosphodiester phosphodiesterase 101043 3252515 LBA0101 Lactobacillus acidophilus NCFM glycerophosphodiester phosphodiesterase YP_193033.1 99286 D 272621 CDS YP_193034.1 58336449 3252533 101104..101244 1 NC_006814.3 hypothetical protein 101244 3252533 LBA0102 Lactobacillus acidophilus NCFM hypothetical protein YP_193034.1 101104 D 272621 CDS YP_193035.1 58336450 3252536 101346..102206 1 NC_006814.3 hypothetical protein 102206 3252536 LBA0103 Lactobacillus acidophilus NCFM hypothetical protein YP_193035.1 101346 D 272621 CDS YP_193036.1 58336451 3252539 102190..102348 1 NC_006814.3 hypothetical protein 102348 3252539 LBA0104 Lactobacillus acidophilus NCFM hypothetical protein YP_193036.1 102190 D 272621 CDS YP_193039.1 58336454 3252548 103668..104792 1 NC_006814.3 COG3405 Endoglucanase Y; beta-glucanase 104792 3252548 LBA0107 Lactobacillus acidophilus NCFM beta-glucanase YP_193039.1 103668 D 272621 CDS YP_193040.1 58336455 3252554 104860..105507 1 NC_006814.3 hydrolase 105507 3252554 LBA0108 Lactobacillus acidophilus NCFM hydrolase YP_193040.1 104860 D 272621 CDS YP_193041.1 58336456 3252575 105508..106425 1 NC_006814.3 COG1403 Restriction endonuclease; hypothetical protein 106425 3252575 LBA0109 Lactobacillus acidophilus NCFM hypothetical protein YP_193041.1 105508 D 272621 CDS YP_193042.1 58336457 3252578 complement(106519..107448) 1 NC_006814.3 hypothetical protein 107448 3252578 LBA0110 Lactobacillus acidophilus NCFM hypothetical protein YP_193042.1 106519 R 272621 CDS YP_193043.1 58336458 3252587 complement(107525..108280) 1 NC_006814.3 glutamate ATP binding protein 108280 3252587 LBA0111 Lactobacillus acidophilus NCFM glutamate ATP binding protein YP_193043.1 107525 R 272621 CDS YP_193044.1 58336459 3252596 complement(108280..109893) 1 NC_006814.3 glutamine ABC transporter 109893 3252596 LBA0112 Lactobacillus acidophilus NCFM glutamine ABC transporter YP_193044.1 108280 R 272621 CDS YP_193045.1 58336460 3252623 complement(110225..110857) 1 NC_006814.3 COG2094 3-methyladenine DNA glycosylase; 3-methyladenine DNA glycosylase 110857 3252623 LBA0113 Lactobacillus acidophilus NCFM 3-methyladenine DNA glycosylase YP_193045.1 110225 R 272621 CDS YP_193046.1 58336461 3252640 110925..111284 1 NC_006814.3 COG3189 Uncharacterized conserved protein; hypothetical protein 111284 3252640 LBA0114 Lactobacillus acidophilus NCFM hypothetical protein YP_193046.1 110925 D 272621 CDS YP_193047.1 58336462 3252641 complement(111331..112119) 1 NC_006814.3 TerC; hypothetical protein 112119 terC 3252641 terC Lactobacillus acidophilus NCFM hypothetical protein YP_193047.1 111331 R 272621 CDS YP_193048.1 58336463 3252645 complement(112312..112482) 1 NC_006814.3 methyltransferase 112482 3252645 LBA0116 Lactobacillus acidophilus NCFM methyltransferase YP_193048.1 112312 R 272621 CDS YP_193049.1 58336464 3252648 complement(112683..113402) 1 NC_006814.3 Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase 113402 3252648 LBA0117 Lactobacillus acidophilus NCFM NAD-dependent deacetylase YP_193049.1 112683 R 272621 CDS YP_193050.1 58336465 3252661 113477..113956 1 NC_006814.3 hypothetical protein 113956 3252661 LBA0118 Lactobacillus acidophilus NCFM hypothetical protein YP_193050.1 113477 D 272621 CDS YP_193051.1 58336466 3252665 complement(113960..115417) 1 NC_006814.3 cardiolipin synthase 115417 3252665 LBA0119 Lactobacillus acidophilus NCFM cardiolipin synthase YP_193051.1 113960 R 272621 CDS YP_193052.1 58336467 3252675 complement(115439..116365) 1 NC_006814.3 hypothetical protein 116365 3252675 LBA0120 Lactobacillus acidophilus NCFM hypothetical protein YP_193052.1 115439 R 272621 CDS YP_193053.1 58336468 3252682 116459..117205 1 NC_006814.3 COG0328 Ribonuclease HI; ribonuclease H 117205 3252682 LBA0121 Lactobacillus acidophilus NCFM ribonuclease H YP_193053.1 116459 D 272621 CDS YP_193054.1 58336469 3252685 complement(117249..118190) 1 NC_006814.3 COG4086 Predicted secreted protein; hypothetical protein 118190 3252685 LBA0122 Lactobacillus acidophilus NCFM hypothetical protein YP_193054.1 117249 R 272621 CDS YP_193055.1 58336470 3252694 118380..119195 1 NC_006814.3 EpsV; polysaccharide biosynthesis protein 119195 epsV 3252694 epsV Lactobacillus acidophilus NCFM polysaccharide biosynthesis protein YP_193055.1 118380 D 272621 CDS YP_193056.1 58336471 3252715 119208..119864 1 NC_006814.3 oxidoreductase 119864 3252715 LBA0124 Lactobacillus acidophilus NCFM oxidoreductase YP_193056.1 119208 D 272621 CDS YP_193057.1 58336472 3252727 119982..120791 1 NC_006814.3 COG1396 Predicted transcriptional regulators; hypothetical protein 120791 3252727 LBA0125 Lactobacillus acidophilus NCFM hypothetical protein YP_193057.1 119982 D 272621 CDS YP_193058.1 58336473 3252732 120891..121307 1 NC_006814.3 membrane protein; hypothetical protein 121307 3252732 LBA0126 Lactobacillus acidophilus NCFM hypothetical protein YP_193058.1 120891 D 272621 CDS YP_193059.1 58336474 3252733 complement(121538..122779) 1 NC_006814.3 transposase 122779 3252733 LBA0127 Lactobacillus acidophilus NCFM transposase YP_193059.1 121538 R 272621 CDS YP_193060.1 58336475 3252742 122924..123202 1 NC_006814.3 COG2865 Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain; hypothetical protein 123202 3252742 LBA0128 Lactobacillus acidophilus NCFM hypothetical protein YP_193060.1 122924 D 272621 CDS YP_193063.1 58336478 3252778 124218..125204 1 NC_006814.3 COG0462 Phosphoribosylpyrophosphate synthetase; ribose-p pyrokinase 125204 3252778 LBA0131 Lactobacillus acidophilus NCFM ribose-p pyrokinase YP_193063.1 124218 D 272621 CDS YP_193064.1 58336479 3252788 125363..126046 1 NC_006814.3 COG1309 transcriptional regulator, TetR family; transcriptional regulator 126046 tetR 3252788 tetR Lactobacillus acidophilus NCFM transcriptional regulator YP_193064.1 125363 D 272621 CDS YP_193065.1 58336480 3252800 126059..126883 1 NC_006814.3 hypothetical protein 126883 3252800 LBA0133 Lactobacillus acidophilus NCFM hypothetical protein YP_193065.1 126059 D 272621 CDS YP_193066.1 58336481 3252817 127010..128485 1 NC_006814.3 GlnP; glutamine ABC transporter permease 128485 glnP 3252817 glnP Lactobacillus acidophilus NCFM glutamine ABC transporter permease YP_193066.1 127010 D 272621 CDS YP_193067.1 58336482 3252822 128478..129215 1 NC_006814.3 GlnQ; glutamine ABC transporter ATP-binding protein 129215 glnQ 3252822 glnQ Lactobacillus acidophilus NCFM glutamine ABC transporter ATP-binding protein YP_193067.1 128478 D 272621 CDS YP_193068.1 58336483 3252827 complement(129261..130499) 1 NC_006814.3 hypothetical protein 130499 3252827 LBA0136 Lactobacillus acidophilus NCFM hypothetical protein YP_193068.1 129261 R 272621 CDS YP_193069.1 58336484 3252845 130652..131734 1 NC_006814.3 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 131734 ddl 3252845 ddl Lactobacillus acidophilus NCFM D-alanyl-alanine synthetase A YP_193069.1 130652 D 272621 CDS YP_193070.1 58336485 3252629 131764..132504 1 NC_006814.3 hypothetical protein 132504 3252629 LBA0138 Lactobacillus acidophilus NCFM hypothetical protein YP_193070.1 131764 D 272621 CDS YP_193071.1 58336486 3252959 132595..133728 1 NC_006814.3 COG5438 Predicted multitransmembrane protein; hypothetical protein 133728 3252959 LBA0139 Lactobacillus acidophilus NCFM hypothetical protein YP_193071.1 132595 D 272621 CDS YP_193072.1 58336487 3252960 133725..134510 1 NC_006814.3 COG5438 Predicted multitransmembrane protein; hypothetical protein 134510 3252960 LBA0140 Lactobacillus acidophilus NCFM hypothetical protein YP_193072.1 133725 D 272621 CDS YP_193073.1 58336488 3252965 134482..135303 1 NC_006814.3 COG0657 Esterase-lipase; acetyl esterase 135303 3252965 LBA0141 Lactobacillus acidophilus NCFM acetyl esterase YP_193073.1 134482 D 272621 CDS YP_193074.1 58336489 3252975 135287..135460 1 NC_006814.3 hypothetical protein 135460 3252975 LBA0142 Lactobacillus acidophilus NCFM hypothetical protein YP_193074.1 135287 D 272621 CDS YP_193075.1 58336490 3252977 complement(135728..138742) 1 NC_006814.3 alpha-glucosidase 138742 3252977 LBA0143 Lactobacillus acidophilus NCFM alpha-glucosidase YP_193075.1 135728 R 272621 CDS YP_193076.1 58336491 3253011 138898..140052 1 NC_006814.3 COG1820 N-acetylglucosamine-6-phosphate deacetylase; n-acetylglucosamine-6-P deacetylase 140052 3253011 LBA0144 Lactobacillus acidophilus NCFM n-acetylglucosamine-6-P deacetylase YP_193076.1 138898 D 272621 CDS YP_193077.1 58336492 3253012 complement(140422..140901) 1 NC_006814.3 2-deoxyribosyltransferase 140901 3253012 LBA0145 Lactobacillus acidophilus NCFM 2-deoxyribosyltransferase YP_193077.1 140422 R 272621 CDS YP_193078.1 58336493 3253065 141014..141502 1 NC_006814.3 PTS system transporter subunit IIA 141502 3253065 LBA0146 Lactobacillus acidophilus NCFM PTS system transporter subunit IIA YP_193078.1 141014 D 272621 CDS YP_193079.1 58336494 3253081 complement(141523..142326) 1 NC_006814.3 COG2365 protein tyrosine-serine phosphatase; protein tyrosine phosphatase 142326 3253081 LBA0147 Lactobacillus acidophilus NCFM protein tyrosine phosphatase YP_193079.1 141523 R 272621 CDS YP_193080.1 58336495 3253096 142307..142435 1 NC_006814.3 hypothetical protein 142435 3253096 LBA0148 Lactobacillus acidophilus NCFM hypothetical protein YP_193080.1 142307 D 272621 CDS YP_193081.1 58336496 3252039 142476..142961 1 NC_006814.3 nucleotide-binding protein 142961 uspA 3252039 uspA Lactobacillus acidophilus NCFM nucleotide-binding protein YP_193081.1 142476 D 272621 CDS YP_193082.1 58336497 3253024 143090..143215 1 NC_006814.3 hypothetical protein 143215 3253024 LBA0150 Lactobacillus acidophilus NCFM hypothetical protein YP_193082.1 143090 D 272621 CDS YP_193083.1 58336498 3252310 143306..144235 1 NC_006814.3 alkylphosphonate ABC transporter 144235 3252310 LBA0151 Lactobacillus acidophilus NCFM alkylphosphonate ABC transporter YP_193083.1 143306 D 272621 CDS YP_193084.1 58336499 3252836 144261..145034 1 NC_006814.3 alkylphosphonate ABC transporter 145034 3252836 LBA0152 Lactobacillus acidophilus NCFM alkylphosphonate ABC transporter YP_193084.1 144261 D 272621 CDS YP_193085.1 58336500 3252880 145034..145831 1 NC_006814.3 alkylphosphonate ABC transporter 145831 3252880 LBA0153 Lactobacillus acidophilus NCFM alkylphosphonate ABC transporter YP_193085.1 145034 D 272621 CDS YP_193086.1 58336501 3251493 145831..146643 1 NC_006814.3 phosphonate ABC transporter 146643 3251493 LBA0154 Lactobacillus acidophilus NCFM phosphonate ABC transporter YP_193086.1 145831 D 272621 CDS YP_193087.1 58336502 3252833 complement(146691..147263) 1 NC_006814.3 DNA-3-methyladenine glycosidase 147263 3252833 LBA0155 Lactobacillus acidophilus NCFM DNA-3-methyladenine glycosidase YP_193087.1 146691 R 272621 CDS YP_193088.1 58336503 3252449 147414..147899 1 NC_006814.3 hypothetical protein 147899 3252449 LBA0156 Lactobacillus acidophilus NCFM hypothetical protein YP_193088.1 147414 D 272621 CDS YP_193089.1 58336504 3252586 147955..149352 1 NC_006814.3 hypothetical protein 149352 3252586 LBA0157 Lactobacillus acidophilus NCFM hypothetical protein YP_193089.1 147955 D 272621 CDS YP_193090.1 58336505 3252935 149468..151417 1 NC_006814.3 COG0367 Asparagine synthase (glutamine-hydrolyzing); asn synthetase 151417 asnH 3252935 asnH Lactobacillus acidophilus NCFM asn synthetase YP_193090.1 149468 D 272621 CDS YP_193091.1 58336506 3252813 151439..152707 1 NC_006814.3 COG3919 Predicted ATP-grasp enzyme; hypothetical protein 152707 3252813 LBA0159 Lactobacillus acidophilus NCFM hypothetical protein YP_193091.1 151439 D 272621 CDS YP_193092.1 58336507 3252314 152886..155081 1 NC_006814.3 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 155081 3252314 LBA0160 Lactobacillus acidophilus NCFM anaerobic ribonucleoside triphosphate reductase YP_193092.1 152886 D 272621 CDS YP_193093.1 58336508 3252123 155065..155778 1 NC_006814.3 anaerobic NTP reductase or activator protein 155778 3252123 LBA0161 Lactobacillus acidophilus NCFM anaerobic NTP reductase or activator protein YP_193093.1 155065 D 272621 CDS YP_193094.1 58336509 3252158 155835..156398 1 NC_006814.3 hypothetical protein 156398 3252158 LBA0162 Lactobacillus acidophilus NCFM hypothetical protein YP_193094.1 155835 D 272621 CDS YP_193095.1 58336510 3252832 156398..157609 1 NC_006814.3 COG2461 Uncharacterized conserved protein; hypothetical protein 157609 3252832 LBA0163 Lactobacillus acidophilus NCFM hypothetical protein YP_193095.1 156398 D 272621 CDS YP_193096.1 58336511 3253047 157716..158933 1 NC_006814.3 efflux permease; multidrug resistance protein 158933 3253047 LBA0164 Lactobacillus acidophilus NCFM multidrug resistance protein YP_193096.1 157716 D 272621 CDS YP_193097.1 58336512 3252650 159007..160959 1 NC_006814.3 PepO; COG3590 Predicted metalloendopeptidase; neutral endopeptidase 160959 pepO 3252650 pepO Lactobacillus acidophilus NCFM neutral endopeptidase YP_193097.1 159007 D 272621 CDS YP_193098.1 58336513 3252439 complement(161203..163053) 1 NC_006814.3 COG3158 K+ transporter; K+ uptake protein 163053 3252439 LBA0166 Lactobacillus acidophilus NCFM K+ uptake protein YP_193098.1 161203 R 272621 CDS YP_193099.1 58336514 3252271 complement(163671..164081) 1 NC_006814.3 hypothetical protein 164081 3252271 LBA0167 Lactobacillus acidophilus NCFM hypothetical protein YP_193099.1 163671 R 272621 CDS YP_193100.1 58336515 3253050 complement(164184..164633) 1 NC_006814.3 Spore germination protein GerIA; hypothetical protein 164633 3253050 LBA0168 Lactobacillus acidophilus NCFM hypothetical protein YP_193100.1 164184 R 272621 CDS YP_193101.1 58336516 3252774 165277..166611 1 NC_006814.3 SlpA; S-layer protein precursor (surface layer protein) (SA-protein); S-layer protein 166611 slpA 3252774 slpA Lactobacillus acidophilus NCFM S-layer protein YP_193101.1 165277 D 272621 CDS YP_193102.1 58336517 3253019 complement(166686..167051) 1 NC_006814.3 6-pyruvoyl tetrahydrobiopterin synthase 167051 3253019 LBA0170 Lactobacillus acidophilus NCFM 6-pyruvoyl tetrahydrobiopterin synthase YP_193102.1 166686 R 272621 CDS YP_193103.1 58336518 3252862 complement(167017..168378) 1 NC_006814.3 glycosyltransferase 168378 3252862 LBA0171 Lactobacillus acidophilus NCFM glycosyltransferase YP_193103.1 167017 R 272621 CDS YP_193104.1 58336519 3252792 complement(168378..169499) 1 NC_006814.3 Uncharacterized conserved membrane protein; hypothetical protein 169499 3252792 LBA0173 Lactobacillus acidophilus NCFM hypothetical protein YP_193104.1 168378 R 272621 CDS YP_193105.1 58336520 3252692 complement(169584..170957) 1 NC_006814.3 SlpB; conserved protein; S-layer protein 170957 slpB 3252692 slpB Lactobacillus acidophilus NCFM S-layer protein YP_193105.1 169584 R 272621 CDS YP_193106.1 58336521 3252343 171321..172550 1 NC_006814.3 N-acetylmuramidase 172550 3252343 LBA0176 Lactobacillus acidophilus NCFM N-acetylmuramidase YP_193106.1 171321 D 272621 CDS YP_193107.1 58336522 3252902 172569..173663 1 NC_006814.3 autolysin, amidase 173663 3252902 LBA0177 Lactobacillus acidophilus NCFM autolysin, amidase YP_193107.1 172569 D 272621 CDS YP_193108.1 58336523 3252600 173787..175622 1 NC_006814.3 Na+-H+ antiporter 175622 3252600 LBA0181 Lactobacillus acidophilus NCFM Na+-H+ antiporter YP_193108.1 173787 D 272621 CDS YP_193109.1 58336524 3252036 complement(175712..176677) 1 NC_006814.3 oxidoreductase 176677 3252036 LBA0182 Lactobacillus acidophilus NCFM oxidoreductase YP_193109.1 175712 R 272621 CDS YP_193110.1 58336525 3252984 complement(176689..177483) 1 NC_006814.3 GMP synthetase; DNA polymerase 177483 3252984 LBA0183 Lactobacillus acidophilus NCFM DNA polymerase YP_193110.1 176689 R 272621 CDS YP_193111.1 58336526 3252660 complement(177558..178319) 1 NC_006814.3 hypothetical protein 178319 3252660 LBA0184 Lactobacillus acidophilus NCFM hypothetical protein YP_193111.1 177558 R 272621 CDS YP_193112.1 58336527 3252143 178485..179177 1 NC_006814.3 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 179177 gpmA 3252143 gpmA Lactobacillus acidophilus NCFM phosphoglyceromutase YP_193112.1 178485 D 272621 CDS YP_193113.1 58336528 3253104 179395..179997 1 NC_006814.3 pyrrolidone carboxyl peptidase 179997 3253104 LBA0186 Lactobacillus acidophilus NCFM pyrrolidone carboxyl peptidase YP_193113.1 179395 D 272621 CDS YP_193114.1 58336529 3253071 180061..180621 1 NC_006814.3 hypothetical protein 180621 3253071 LBA0187 Lactobacillus acidophilus NCFM hypothetical protein YP_193114.1 180061 D 272621 CDS YP_193115.1 58336530 3252099 180723..181826 1 NC_006814.3 COG1316 transcriptional regulator; transcriptional regulator 181826 3252099 LBA0188 Lactobacillus acidophilus NCFM transcriptional regulator YP_193115.1 180723 D 272621 CDS YP_193116.1 58336531 3252085 181826..182443 1 NC_006814.3 COG0344 Predicted membrane protein; membrane protein 182443 3252085 LBA0189 Lactobacillus acidophilus NCFM membrane protein YP_193116.1 181826 D 272621 CDS YP_193117.1 58336532 3252057 182486..185476 1 NC_006814.3 glucan modification protein 185476 3252057 LBA0190 Lactobacillus acidophilus NCFM glucan modification protein YP_193117.1 182486 D 272621 CDS YP_193118.1 58336533 3251183 185577..186968 1 NC_006814.3 hypothetical protein CBG06205; fibronectin domain-containing protein 186968 3251183 LBA0191 Lactobacillus acidophilus NCFM fibronectin domain-containing protein YP_193118.1 185577 D 272621 CDS YP_193119.1 58336534 3252060 187222..188484 1 NC_006814.3 COG0162 Tyrosyl-tRNA synthetase; Tyr-tRNA synthetase 188484 3252060 LBA0192 Lactobacillus acidophilus NCFM Tyr-tRNA synthetase YP_193119.1 187222 D 272621 CDS YP_193120.1 58336535 3252048 188592..188948 1 NC_006814.3 ENSANGP00000002842; hypothetical protein 188948 3252048 LBA0193 Lactobacillus acidophilus NCFM hypothetical protein YP_193120.1 188592 D 272621 CDS YP_193121.1 58336536 3252046 189152..190465 1 NC_006814.3 endopeptidase E2; aminopeptidase 190465 pepG 3252046 pepG Lactobacillus acidophilus NCFM aminopeptidase YP_193121.1 189152 D 272621 CDS YP_193122.1 58336537 3252251 190465..191118 1 NC_006814.3 hydrolase 191118 3252251 LBA0196 Lactobacillus acidophilus NCFM hydrolase YP_193122.1 190465 D 272621 CDS YP_193123.1 58336538 3252244 191288..192913 1 NC_006814.3 ABC transporter; OppA; oligopeptide binding protein 192913 oppA 3252244 oppA Lactobacillus acidophilus NCFM oligopeptide binding protein YP_193123.1 191288 D 272621 CDS YP_193124.1 58336539 3252239 192993..194621 1 NC_006814.3 ABC transporter; OppA; peptide binding protein 194621 oppA 3252239 oppA Lactobacillus acidophilus NCFM peptide binding protein YP_193124.1 192993 D 272621 CDS YP_193125.1 58336540 3252230 194769..195911 1 NC_006814.3 inosine-5'-monophosphate dehydrogenase 195911 3252230 LBA0199 Lactobacillus acidophilus NCFM inosine-5'-monophosphate dehydrogenase YP_193125.1 194769 D 272621 CDS YP_193126.1 58336541 3252215 196073..197002 1 NC_006814.3 oligopeptide ABC transporter; permease 197002 oppB 3252215 oppB Lactobacillus acidophilus NCFM permease YP_193126.1 196073 D 272621 CDS YP_193127.1 58336542 3252204 197010..198041 1 NC_006814.3 OppC; permease ( oligopeptide ABC transporter) 198041 oppC 3252204 oppC Lactobacillus acidophilus NCFM permease ( oligopeptide ABC transporter) YP_193127.1 197010 D 272621 CDS YP_193128.1 58336543 3252202 198057..199115 1 NC_006814.3 oligopept. ABC transporter; ATP-binding protein 199115 oppD 3252202 oppD Lactobacillus acidophilus NCFM ATP-binding protein YP_193128.1 198057 D 272621 CDS YP_193129.1 58336544 3252178 199136..200080 1 NC_006814.3 OppF; ATP binding protein ( oligopeptide ABC transporter ) 200080 oppF 3252178 oppF Lactobacillus acidophilus NCFM ATP binding protein ( oligopeptide ABC transporter ) YP_193129.1 199136 D 272621 CDS YP_193130.1 58336545 3252177 complement(200133..201449) 1 NC_006814.3 Aminopeptidase E; aminopeptidase 201449 pepE 3252177 pepE Lactobacillus acidophilus NCFM aminopeptidase YP_193130.1 200133 R 272621 CDS YP_193131.1 58336546 3252171 complement(201593..202018) 1 NC_006814.3 heat shock low molecular weight 202018 3252171 LBA0205 Lactobacillus acidophilus NCFM heat shock low molecular weight YP_193131.1 201593 R 272621 CDS YP_193132.1 58336547 3252160 202233..202694 1 NC_006814.3 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 202694 greA 3252160 greA Lactobacillus acidophilus NCFM transcription elongation factor GreA YP_193132.1 202233 D 272621 CDS YP_193133.1 58336548 3252149 202772..203434 1 NC_006814.3 hypothetical protein 203434 3252149 LBA0207 Lactobacillus acidophilus NCFM hypothetical protein YP_193133.1 202772 D 272621 CDS YP_193134.1 58336549 3252146 complement(203601..204200) 1 NC_006814.3 COG2135 Uncharacterized conserved protein; hypothetical protein 204200 3252146 LBA0208 Lactobacillus acidophilus NCFM hypothetical protein YP_193134.1 203601 R 272621 CDS YP_193135.1 58336550 3252122 204306..205328 1 NC_006814.3 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase II 205328 3252122 LBA0209 Lactobacillus acidophilus NCFM tryptophanyl-tRNA synthetase II YP_193135.1 204306 D 272621 CDS YP_193136.1 58336551 3252124 205352..205831 1 NC_006814.3 COG2131 Deoxycytidylate deaminase; dCMP deaminase 205831 3252124 LBA0210 Lactobacillus acidophilus NCFM dCMP deaminase YP_193136.1 205352 D 272621 CDS YP_193137.1 58336552 3252125 205812..206429 1 NC_006814.3 hypothetical protein 206429 3252125 LBA0211 Lactobacillus acidophilus NCFM hypothetical protein YP_193137.1 205812 D 272621 CDS YP_193138.1 58336553 3252116 206719..209382 1 NC_006814.3 COG0474 Cation transport ATPase; cation transporter P-ATPase 209382 3252116 LBA0212 Lactobacillus acidophilus NCFM cation transporter P-ATPase YP_193138.1 206719 D 272621 CDS YP_193139.1 58336554 3251475 209479..211455 1 NC_006814.3 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 211455 3251475 LBA0213 Lactobacillus acidophilus NCFM methionyl-tRNA synthetase YP_193139.1 209479 D 272621 CDS YP_193140.1 58336555 3252102 211455..212222 1 NC_006814.3 COG0084 Mg-dependent DNAse; hypothetical protein 212222 3252102 LBA0214 Lactobacillus acidophilus NCFM hypothetical protein YP_193140.1 211455 D 272621 CDS YP_193141.1 58336556 3252091 212209..212796 1 NC_006814.3 primase like 212796 3252091 LBA0215 Lactobacillus acidophilus NCFM primase like YP_193141.1 212209 D 272621 CDS YP_193142.1 58336557 3252104 212786..213670 1 NC_006814.3 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 213670 ksgA 3252104 ksgA Lactobacillus acidophilus NCFM dimethyladenosine transferase YP_193142.1 212786 D 272621 CDS YP_193143.1 58336558 3252109 213732..213989 1 NC_006814.3 COG4466 Uncharacterized protein conserved in bacteria; hypothetical protein 213989 3252109 LBA0217 Lactobacillus acidophilus NCFM hypothetical protein YP_193143.1 213732 D 272621 CDS YP_193144.1 58336559 3252059 214093..214923 1 NC_006814.3 PurR; pur operon repressor 214923 purR 3252059 purR Lactobacillus acidophilus NCFM pur operon repressor YP_193144.1 214093 D 272621 CDS YP_193145.1 58336560 3252067 214971..216350 1 NC_006814.3 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 216350 glmU 3252067 glmU Lactobacillus acidophilus NCFM bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_193145.1 214971 D 272621 CDS YP_193146.1 58336561 3252081 216570..217088 1 NC_006814.3 potential frameshift to 221; S-layer protein 217088 3252081 LBA0220 Lactobacillus acidophilus NCFM S-layer protein YP_193146.1 216570 D 272621 CDS YP_193147.1 58336562 3251508 217122..217655 1 NC_006814.3 potential frameshift to 220; S-layer protein 217655 3251508 LBA0221 Lactobacillus acidophilus NCFM S-layer protein YP_193147.1 217122 D 272621 CDS YP_193148.1 58336563 3252093 217766..218614 1 NC_006814.3 chloroquine resistance marker protein; hypothetical protein 218614 3252093 LBA0222 Lactobacillus acidophilus NCFM hypothetical protein YP_193148.1 217766 D 272621 CDS YP_193149.1 58336564 3252068 218630..220429 1 NC_006814.3 CdpA; surface layer protein; cell separation protein 220429 cdpA 3252068 cdpA Lactobacillus acidophilus NCFM cell separation protein YP_193149.1 218630 D 272621 CDS YP_193150.1 58336565 3252108 220709..221683 1 NC_006814.3 COG0462 Phosphoribosylpyrophosphate synthetase; ribose-p-pyrophosphokinase 221683 prsA 3252108 prsA Lactobacillus acidophilus NCFM ribose-p-pyrophosphokinase YP_193150.1 220709 D 272621 CDS YP_193151.1 58336566 3252433 complement(221735..223162) 1 NC_006814.3 6-phospho-beta-glucosidase; 6-p-beta-glucosidase 223162 3252433 LBA0225 Lactobacillus acidophilus NCFM 6-p-beta-glucosidase YP_193151.1 221735 R 272621 CDS YP_193152.1 58336567 3252414 complement(223292..224008) 1 NC_006814.3 transcriptional regulator 224008 3252414 LBA0226 Lactobacillus acidophilus NCFM transcriptional regulator YP_193152.1 223292 R 272621 CDS YP_193153.1 58336568 3252384 224196..225521 1 NC_006814.3 PTS system, IIC component; PTS system cellobiose-specific transporter subunit IIC 225521 3252384 LBA0227 Lactobacillus acidophilus NCFM PTS system cellobiose-specific transporter subunit IIC YP_193153.1 224196 D 272621 CDS YP_193154.1 58336569 3252366 225591..226499 1 NC_006814.3 transcriptional regulator 226499 3252366 LBA0228 Lactobacillus acidophilus NCFM transcriptional regulator YP_193154.1 225591 D 272621 CDS YP_193155.1 58336570 3252356 complement(226549..226830) 1 NC_006814.3 hypothetical protein 226830 3252356 LBA0229 Lactobacillus acidophilus NCFM hypothetical protein YP_193155.1 226549 R 272621 CDS YP_193156.1 58336571 3252332 complement(226860..228224) 1 NC_006814.3 COG1078 HD family phosphohydrolases; hypothetical protein 228224 3252332 LBA0230 Lactobacillus acidophilus NCFM hypothetical protein YP_193156.1 226860 R 272621 CDS YP_193157.1 58336572 3252328 228340..228744 1 NC_006814.3 hypothetical protein 228744 3252328 LBA0231 Lactobacillus acidophilus NCFM hypothetical protein YP_193157.1 228340 D 272621 CDS YP_193158.1 58336573 3252312 228791..229345 1 NC_006814.3 participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; DNA-directed RNA polymerase subunit delta 229345 3252312 LBA0232 Lactobacillus acidophilus NCFM DNA-directed RNA polymerase subunit delta YP_193158.1 228791 D 272621 CDS YP_193159.1 58336574 3252279 229463..231082 1 NC_006814.3 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 231082 pyrG 3252279 pyrG Lactobacillus acidophilus NCFM CTP synthetase YP_193159.1 229463 D 272621 CDS YP_193160.1 58336575 3252287 231212..232507 1 NC_006814.3 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 232507 3252287 LBA0234 Lactobacillus acidophilus NCFM UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_193160.1 231212 D 272621 CDS YP_193163.1 58336578 3252274 complement(234089..234910) 1 NC_006814.3 raffinose operon transcriptional regulator protein RafR; transcriptional regulator raffinose operon 234910 3252274 LBA0237 Lactobacillus acidophilus NCFM transcriptional regulator raffinose operon YP_193163.1 234089 R 272621 CDS YP_193164.1 58336579 3252269 234961..235590 1 NC_006814.3 hypothetical protein 235590 3252269 LBA0238 Lactobacillus acidophilus NCFM hypothetical protein YP_193164.1 234961 D 272621 CDS YP_193165.1 58336580 3252222 complement(235684..236964) 1 NC_006814.3 xanthine permease 236964 3252222 LBA0239 Lactobacillus acidophilus NCFM xanthine permease YP_193165.1 235684 R 272621 CDS YP_193166.1 58336581 3252173 complement(236972..237550) 1 NC_006814.3 Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine; xanthine phosphoribosyltransferase 237550 3252173 LBA0240 Lactobacillus acidophilus NCFM xanthine phosphoribosyltransferase YP_193166.1 236972 R 272621 CDS YP_193167.1 58336582 3252159 complement(237782..238552) 1 NC_006814.3 hypothetical protein 238552 3252159 LBA0242 Lactobacillus acidophilus NCFM hypothetical protein YP_193167.1 237782 R 272621 CDS YP_193168.1 58336583 3252161 complement(238636..239601) 1 NC_006814.3 COG1396 Predicted transcriptional regulators; transcriptional regulator 239601 3252161 LBA0244 Lactobacillus acidophilus NCFM transcriptional regulator YP_193168.1 238636 R 272621 CDS YP_193169.1 58336584 3252155 239826..241376 1 NC_006814.3 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 241376 guaA 3252155 guaA Lactobacillus acidophilus NCFM GMP synthase YP_193169.1 239826 D 272621 CDS YP_193170.1 58336585 3252213 241930..242784 1 NC_006814.3 daunorubicin resistance protein 242784 3252213 LBA0246 Lactobacillus acidophilus NCFM daunorubicin resistance protein YP_193170.1 241930 D 272621 CDS YP_193171.1 58336586 3252223 242784..243650 1 NC_006814.3 ABC transporter 243650 3252223 LBA0247 Lactobacillus acidophilus NCFM ABC transporter YP_193171.1 242784 D 272621 CDS YP_193172.1 58336587 3252229 243640..244092 1 NC_006814.3 hypothetical protein 244092 3252229 LBA0248 Lactobacillus acidophilus NCFM hypothetical protein YP_193172.1 243640 D 272621 CDS YP_193173.1 58336588 3252235 244511..245014 1 NC_006814.3 acetyltransferase 245014 3252235 LBA0249 Lactobacillus acidophilus NCFM acetyltransferase YP_193173.1 244511 D 272621 CDS YP_193174.1 58336589 3252145 245348..246052 1 NC_006814.3 hypothetical protein 246052 3252145 LBA0250 Lactobacillus acidophilus NCFM hypothetical protein YP_193174.1 245348 D 272621 CDS YP_193175.1 58336590 3252259 246043..246603 1 NC_006814.3 potential frameshift to 252; similar to multidrug resistance protein B; multidrug resistance protein 246603 3252259 LBA0251 Lactobacillus acidophilus NCFM multidrug resistance protein YP_193175.1 246043 D 272621 CDS YP_193176.1 58336591 3252260 246763..247116 1 NC_006814.3 potential frameshift to 251; multidrug resistance protein 247116 3252260 LBA0252 Lactobacillus acidophilus NCFM multidrug resistance protein YP_193176.1 246763 D 272621 CDS YP_193177.1 58336592 3252257 247165..247425 1 NC_006814.3 potential frameshift to 251; multidrug resistance protein 247425 3252257 LBA0253 Lactobacillus acidophilus NCFM multidrug resistance protein YP_193177.1 247165 D 272621 CDS YP_193178.1 58336593 3252190 247510..247728 1 NC_006814.3 similar to turkey astrovirus protein; hypothetical protein 247728 3252190 LBA0254 Lactobacillus acidophilus NCFM hypothetical protein YP_193178.1 247510 D 272621 CDS YP_193179.1 58336594 3252144 247728..248189 1 NC_006814.3 S-methyltransferase 248189 3252144 LBA0255 Lactobacillus acidophilus NCFM S-methyltransferase YP_193179.1 247728 D 272621 CDS YP_193180.1 58336595 3252214 248261..248467 1 NC_006814.3 hypothetical protein 248467 3252214 LBA0256 Lactobacillus acidophilus NCFM hypothetical protein YP_193180.1 248261 D 272621 CDS YP_193181.1 58336596 3252256 248537..248731 1 NC_006814.3 hypothetical protein 248731 3252256 LBA0257 Lactobacillus acidophilus NCFM hypothetical protein YP_193181.1 248537 D 272621 CDS YP_193182.1 58336597 3252101 complement(248787..249374) 1 NC_006814.3 hypothetical protein 249374 3252101 LBA0258 Lactobacillus acidophilus NCFM hypothetical protein YP_193182.1 248787 R 272621 CDS YP_193183.1 58336598 3252168 complement(249429..249746) 1 NC_006814.3 TEP3 protein; hypothetical protein 249746 3252168 LBA0259 Lactobacillus acidophilus NCFM hypothetical protein YP_193183.1 249429 R 272621 CDS YP_193184.1 58336599 3252527 250073..250354 1 NC_006814.3 hypothetical protein 250354 3252527 LBA0260 Lactobacillus acidophilus NCFM hypothetical protein YP_193184.1 250073 D 272621 CDS YP_193185.1 58336600 3252509 250411..251646 1 NC_006814.3 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 251646 glyA 3252509 glyA Lactobacillus acidophilus NCFM serine hydroxymethyltransferase YP_193185.1 250411 D 272621 CDS YP_193186.1 58336601 3252487 251738..253330 1 NC_006814.3 COG0531 Amino acid transporters; aa transporter 253330 3252487 LBA0262 Lactobacillus acidophilus NCFM aa transporter YP_193186.1 251738 D 272621 CDS YP_193187.1 58336602 3252485 complement(253371..254219) 1 NC_006814.3 hypothetical protein 254219 3252485 LBA0263 Lactobacillus acidophilus NCFM hypothetical protein YP_193187.1 253371 R 272621 CDS YP_193188.1 58336603 3252454 254319..255938 1 NC_006814.3 COG0366 Glycosidases; glucan 1,6-alpha-glucosidase 255938 3252454 LBA0264 Lactobacillus acidophilus NCFM glucan 1,6-alpha-glucosidase YP_193188.1 254319 D 272621 CDS YP_193189.1 58336604 3252324 256048..256293 1 NC_006814.3 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 256293 rpmE2 3252324 rpmE2 Lactobacillus acidophilus NCFM 50S ribosomal protein L31 YP_193189.1 256048 D 272621 CDS YP_193190.1 58336605 3252331 256420..257787 1 NC_006814.3 COG0770 UDP-N-acetylmuramyl pentapeptide synthase; d-ala-d-ala adding enzyme 257787 3252331 LBA0266 Lactobacillus acidophilus NCFM d-ala-d-ala adding enzyme YP_193190.1 256420 D 272621 CDS YP_193191.1 58336606 3252339 257801..259288 1 NC_006814.3 YdbR; ATP-dependent RNA helicase-like protein 259288 3252339 LBA0267 Lactobacillus acidophilus NCFM ATP-dependent RNA helicase-like protein YP_193191.1 257801 D 272621 CDS YP_193192.1 58336607 3252299 259369..259725 1 NC_006814.3 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 259725 acpS 3252299 acpS Lactobacillus acidophilus NCFM 4'-phosphopantetheinyl transferase YP_193192.1 259369 D 272621 CDS YP_193193.1 58336608 3252362 259725..260855 1 NC_006814.3 alanine racemase; ala racemase 260855 3252362 LBA0269 Lactobacillus acidophilus NCFM ala racemase YP_193193.1 259725 D 272621 CDS YP_193194.1 58336609 3252364 complement(260916..261623) 1 NC_006814.3 COG0517 FOG CBS domain; hypothetical protein 261623 3252364 LBA0270 Lactobacillus acidophilus NCFM hypothetical protein YP_193194.1 260916 R 272621 CDS YP_193195.1 58336610 3252415 complement(261799..262770) 1 NC_006814.3 L-LDH 262770 3252415 LBA0271 Lactobacillus acidophilus NCFM L-LDH YP_193195.1 261799 R 272621 CDS YP_193196.1 58336611 3252428 262905..263462 1 NC_006814.3 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 263462 3252428 LBA0272 Lactobacillus acidophilus NCFM peptidyl-tRNA hydrolase YP_193196.1 262905 D 272621 CDS YP_193197.1 58336612 3252435 263464..266961 1 NC_006814.3 TrcF; transcriptional repair coupling factor 266961 trcF 3252435 trcF Lactobacillus acidophilus NCFM transcriptional repair coupling factor YP_193197.1 263464 D 272621 CDS YP_193198.1 58336613 3252350 266978..267220 1 NC_006814.3 COG1188 Ribosome-associated heat shock protein; hypothetical protein 267220 3252350 LBA0274 Lactobacillus acidophilus NCFM hypothetical protein YP_193198.1 266978 D 272621 CDS YP_193199.1 58336614 3252416 267305..267682 1 NC_006814.3 COG2919 Septum formation initiator; hypothetical protein 267682 3252416 LBA0275 Lactobacillus acidophilus NCFM hypothetical protein YP_193199.1 267305 D 272621 CDS YP_193200.1 58336615 3252448 267682..268044 1 NC_006814.3 30S ribosomal protein S1 268044 3252448 LBA0276 Lactobacillus acidophilus NCFM 30S ribosomal protein S1 YP_193200.1 267682 D 272621 CDS YP_193201.1 58336616 3252318 268072..269343 1 NC_006814.3 cell cycle 269343 3252318 LBA0277 Lactobacillus acidophilus NCFM cell cycle YP_193201.1 268072 D 272621 CDS YP_193202.1 58336617 3252438 269439..271595 1 NC_006814.3 FtsH; COG0465 ATP-dependent Zn proteases; cell division protein 271595 ftsH 3252438 ftsH Lactobacillus acidophilus NCFM cell division protein YP_193202.1 269439 D 272621 CDS YP_193203.1 58336618 3252368 271652..272542 1 NC_006814.3 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 272542 hslO 3252368 hslO Lactobacillus acidophilus NCFM Hsp33-like chaperonin YP_193203.1 271652 D 272621 CDS YP_193204.1 58336619 3252305 272619..273647 1 NC_006814.3 COG0042 tRNA-dihydrouridine synthase; transcriptional regulator 273647 3252305 LBA0280 Lactobacillus acidophilus NCFM transcriptional regulator YP_193204.1 272619 D 272621 CDS YP_193205.1 58336620 3252252 273663..275213 1 NC_006814.3 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 275213 lysS 3252252 lysS Lactobacillus acidophilus NCFM lysyl-tRNA synthetase YP_193205.1 273663 D 272621 CDS YP_193206.1 58336621 3252720 275807..276262 1 NC_006814.3 COG1956 GAF domain-containing protein; hypothetical protein 276262 3252720 LBA0282 Lactobacillus acidophilus NCFM hypothetical protein YP_193206.1 275807 D 272621 CDS YP_193207.1 58336622 3252699 276367..278844 1 NC_006814.3 ClpC; ATPase 278844 clpC 3252699 clpC Lactobacillus acidophilus NCFM ATPase YP_193207.1 276367 D 272621 CDS YP_193208.1 58336623 3252691 279065..282706 1 NC_006814.3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 282706 rpoB 3252691 rpoB Lactobacillus acidophilus NCFM DNA-directed RNA polymerase subunit beta YP_193208.1 279065 D 272621 CDS YP_193209.1 58336624 3252672 282722..286375 1 NC_006814.3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 286375 3252672 LBA0285 Lactobacillus acidophilus NCFM DNA-directed RNA polymerase subunit beta' YP_193209.1 282722 D 272621 CDS YP_193210.1 58336625 3252669 complement(286426..287115) 1 NC_006814.3 type 4 prepilin-like protein leader peptide processing enzyme; prepilin peptidase 287115 3252669 LBA0286 Lactobacillus acidophilus NCFM prepilin peptidase YP_193210.1 286426 R 272621 CDS YP_193211.1 58336626 3252631 287288..287695 1 NC_006814.3 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 287695 rpsL 3252631 rpsL Lactobacillus acidophilus NCFM 30S ribosomal protein S12 YP_193211.1 287288 D 272621 CDS YP_193212.1 58336627 3252622 287711..288181 1 NC_006814.3 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 288181 3252622 LBA0288 Lactobacillus acidophilus NCFM 30S ribosomal protein S7 YP_193212.1 287711 D 272621 CDS YP_193213.1 58336628 3252621 288215..290308 1 NC_006814.3 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 290308 fusA 3252621 fusA Lactobacillus acidophilus NCFM elongation factor G YP_193213.1 288215 D 272621 CDS YP_193214.1 58336629 3252597 290628..290936 1 NC_006814.3 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 290936 rpsJ 3252597 rpsJ Lactobacillus acidophilus NCFM 30S ribosomal protein S10 YP_193214.1 290628 D 272621 CDS YP_193215.1 58336630 3252588 290960..291598 1 NC_006814.3 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 291598 rplC 3252588 rplC Lactobacillus acidophilus NCFM 50S ribosomal protein L3 YP_193215.1 290960 D 272621 CDS YP_193216.1 58336631 3252553 291613..292230 1 NC_006814.3 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 292230 rplD 3252553 rplD Lactobacillus acidophilus NCFM 50S ribosomal protein L4 YP_193216.1 291613 D 272621 CDS YP_193217.1 58336632 3252549 292230..292532 1 NC_006814.3 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 292532 rplW 3252549 rplW Lactobacillus acidophilus NCFM 50S ribosomal protein L23 YP_193217.1 292230 D 272621 CDS YP_193218.1 58336633 3252537 292548..293384 1 NC_006814.3 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 293384 rplB 3252537 rplB Lactobacillus acidophilus NCFM 50S ribosomal protein L2 YP_193218.1 292548 D 272621 CDS YP_193220.1 58336635 3252516 293707..294060 1 NC_006814.3 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 294060 rplV 3252516 rplV Lactobacillus acidophilus NCFM 50S ribosomal protein L22 YP_193220.1 293707 D 272621 CDS YP_193221.1 58336636 3252523 294074..294748 1 NC_006814.3 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 294748 rpsC 3252523 rpsC Lactobacillus acidophilus NCFM 30S ribosomal protein S3 YP_193221.1 294074 D 272621 CDS YP_193222.1 58336637 3252473 294748..295188 1 NC_006814.3 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 295188 rplP 3252473 rplP Lactobacillus acidophilus NCFM 50S ribosomal protein L16 YP_193222.1 294748 D 272621 CDS YP_193223.1 58336638 3252463 295178..295375 1 NC_006814.3 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 295375 rpmC 3252463 rpmC Lactobacillus acidophilus NCFM 50S ribosomal protein L29 YP_193223.1 295178 D 272621 CDS YP_193224.1 58336639 3252482 295394..295660 1 NC_006814.3 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 295660 rpsQ 3252482 rpsQ Lactobacillus acidophilus NCFM 30S ribosomal protein S17 YP_193224.1 295394 D 272621 CDS YP_193225.1 58336640 3252542 295692..296060 1 NC_006814.3 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 296060 rplN 3252542 rplN Lactobacillus acidophilus NCFM 50S ribosomal protein L14 YP_193225.1 295692 D 272621 CDS YP_193226.1 58336641 3252543 296080..296313 1 NC_006814.3 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 296313 rplX 3252543 rplX Lactobacillus acidophilus NCFM 50S ribosomal protein L24 YP_193226.1 296080 D 272621 CDS YP_193227.1 58336642 3252447 296328..296870 1 NC_006814.3 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 296870 rplE 3252447 rplE Lactobacillus acidophilus NCFM 50S ribosomal protein L5 YP_193227.1 296328 D 272621 CDS YP_003864081.1 304650759 9714949 296883..297068 1 NC_006814.3 30S ribosomal protein S14 297068 9714949 LBA0303a Lactobacillus acidophilus NCFM 30S ribosomal protein S14 YP_003864081.1 296883 D 272621 CDS YP_193228.1 58336643 3252610 297094..297492 1 NC_006814.3 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 297492 rpsH 3252610 rpsH Lactobacillus acidophilus NCFM 30S ribosomal protein S8 YP_193228.1 297094 D 272621 CDS YP_193229.1 58336644 3252637 297517..298047 1 NC_006814.3 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 298047 rplF 3252637 rplF Lactobacillus acidophilus NCFM 50S ribosomal protein L6 YP_193229.1 297517 D 272621 CDS YP_193230.1 58336645 3252570 298074..298430 1 NC_006814.3 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 298430 rplR 3252570 rplR Lactobacillus acidophilus NCFM 50S ribosomal protein L18 YP_193230.1 298074 D 272621 CDS YP_193231.1 58336646 3252499 298448..298954 1 NC_006814.3 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 298954 rpsE 3252499 rpsE Lactobacillus acidophilus NCFM 30S ribosomal protein S5 YP_193231.1 298448 D 272621 CDS YP_193232.1 58336647 3252706 298972..299157 1 NC_006814.3 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 299157 rpmD 3252706 rpmD Lactobacillus acidophilus NCFM 50S ribosomal protein L30 YP_193232.1 298972 D 272621 CDS YP_193233.1 58336648 3252678 299181..299621 1 NC_006814.3 late assembly protein; 50S ribosomal protein L15 299621 rplO 3252678 rplO Lactobacillus acidophilus NCFM 50S ribosomal protein L15 YP_193233.1 299181 D 272621 CDS YP_193234.1 58336649 3252721 299621..300916 1 NC_006814.3 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 300916 secY 3252721 secY Lactobacillus acidophilus NCFM preprotein translocase subunit SecY YP_193234.1 299621 D 272621 CDS YP_193235.1 58336650 3252668 300928..301584 1 NC_006814.3 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 301584 adk 3252668 adk Lactobacillus acidophilus NCFM adenylate kinase YP_193235.1 300928 D 272621 CDS YP_193236.1 58336651 3252636 301656..301877 1 NC_006814.3 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 301877 infA 3252636 infA Lactobacillus acidophilus NCFM translation initiation factor IF-1 YP_193236.1 301656 D 272621 CDS YP_193237.1 58336652 3252701 301894..302010 1 NC_006814.3 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 302010 rpmJ 3252701 rpmJ Lactobacillus acidophilus NCFM 50S ribosomal protein L36 YP_193237.1 301894 D 272621 CDS YP_193238.1 58336653 3252526 302035..302385 1 NC_006814.3 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 302385 rpsM 3252526 rpsM Lactobacillus acidophilus NCFM 30S ribosomal protein S13 YP_193238.1 302035 D 272621 CDS YP_193239.1 58336654 3252501 302407..302799 1 NC_006814.3 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 302799 3252501 LBA0316 Lactobacillus acidophilus NCFM 30S ribosomal protein S11 YP_193239.1 302407 D 272621 CDS YP_193240.1 58336655 3252683 302848..303786 1 NC_006814.3 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 303786 3252683 LBA0317 Lactobacillus acidophilus NCFM DNA-directed RNA polymerase subunit alpha YP_193240.1 302848 D 272621 CDS YP_193241.1 58336656 3252653 303811..304194 1 NC_006814.3 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 304194 rplQ 3252653 rplQ Lactobacillus acidophilus NCFM 50S ribosomal protein L17 YP_193241.1 303811 D 272621 CDS YP_193242.1 58336657 3252591 304386..305237 1 NC_006814.3 with CbiNQ forms the ABC transporter for cobalt import; Lactobacillus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit 305237 cbiO 3252591 cbiO Lactobacillus acidophilus NCFM cobalt transporter ATP-binding subunit YP_193242.1 304386 D 272621 CDS YP_193243.1 58336658 3252585 305213..306070 1 NC_006814.3 with CbiNQ forms the ABC transporter for cobalt import; Lactobacillus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit 306070 cbiO 3252585 cbiO Lactobacillus acidophilus NCFM cobalt transporter ATP-binding subunit YP_193243.1 305213 D 272621 CDS YP_193244.1 58336659 3252710 306063..306860 1 NC_006814.3 ABC transporter permease 306860 3252710 LBA0321 Lactobacillus acidophilus NCFM ABC transporter permease YP_193244.1 306063 D 272621 CDS YP_193245.1 58336660 3252671 306863..307651 1 NC_006814.3 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 307651 truA 3252671 truA Lactobacillus acidophilus NCFM tRNA pseudouridine synthase A YP_193245.1 306863 D 272621 CDS YP_193246.1 58336661 3252726 307756..308199 1 NC_006814.3 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 308199 rplM 3252726 rplM Lactobacillus acidophilus NCFM 50S ribosomal protein L13 YP_193246.1 307756 D 272621 CDS YP_193247.1 58336662 3252743 308211..308606 1 NC_006814.3 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 308606 rpsI 3252743 rpsI Lactobacillus acidophilus NCFM 30S ribosomal protein S9 YP_193247.1 308211 D 272621 CDS YP_193248.1 58336663 3252744 complement(308676..309728) 1 NC_006814.3 integrase 309728 3252744 LBA0325 Lactobacillus acidophilus NCFM integrase YP_193248.1 308676 R 272621 CDS YP_193249.1 58336664 3252748 complement(309805..309993) 1 NC_006814.3 hypothetical protein 309993 3252748 LBA0326 Lactobacillus acidophilus NCFM hypothetical protein YP_193249.1 309805 R 272621 CDS YP_193250.1 58336665 3252752 complement(310053..311153) 1 NC_006814.3 RepA; replication initiator protein; replication protein 311153 3252752 LBA0327 Lactobacillus acidophilus NCFM replication protein YP_193250.1 310053 R 272621 CDS YP_193251.1 58336666 3252011 complement(311338..311868) 1 NC_006814.3 hypothetical protein 311868 3252011 LBA0328 Lactobacillus acidophilus NCFM hypothetical protein YP_193251.1 311338 R 272621 CDS YP_193252.1 58336667 3252760 complement(311865..312941) 1 NC_006814.3 FtsK; hypothetical protein; cell division protein 312941 ftsK 3252760 ftsK Lactobacillus acidophilus NCFM cell division protein YP_193252.1 311865 R 272621 CDS YP_193253.1 58336668 3252012 complement(312941..313252) 1 NC_006814.3 hypothetical protein 313252 3252012 LBA0330 Lactobacillus acidophilus NCFM hypothetical protein YP_193253.1 312941 R 272621 CDS YP_193254.1 58336669 3252013 313425..314309 1 NC_006814.3 hypothetical protein 314309 3252013 LBA0331 Lactobacillus acidophilus NCFM hypothetical protein YP_193254.1 313425 D 272621 CDS YP_193255.1 58336670 3252014 314359..317178 1 NC_006814.3 YeeA protein; methylase 317178 3252014 LBA0332 Lactobacillus acidophilus NCFM methylase YP_193255.1 314359 D 272621 CDS YP_193256.1 58336671 3252775 317178..317549 1 NC_006814.3 major head protein; hypothetical protein 317549 3252775 LBA0333 Lactobacillus acidophilus NCFM hypothetical protein YP_193256.1 317178 D 272621 CDS YP_193257.1 58336672 3252783 318099..318239 1 NC_006814.3 hypothetical protein 318239 3252783 LBA0334 Lactobacillus acidophilus NCFM hypothetical protein YP_193257.1 318099 D 272621 CDS YP_193258.1 58336673 3252780 318208..318369 1 NC_006814.3 hypothetical protein 318369 3252780 LBA0335 Lactobacillus acidophilus NCFM hypothetical protein YP_193258.1 318208 D 272621 CDS YP_193259.1 58336674 3252015 complement(318450..319034) 1 NC_006814.3 COG0693 intracellular protease-amidase; 4-methyl-5(beta-hydroxyethyl)-thiazole monophosphate synthesis protein 319034 3252015 LBA0336 Lactobacillus acidophilus NCFM 4-methyl-5(beta-hydroxyethyl)-thiazole monophosphate synthesis protein YP_193259.1 318450 R 272621 CDS YP_193260.1 58336675 3252796 complement(319080..319739) 1 NC_006814.3 2-haloalkanoic acid dehalogenase; hypothetical protein 319739 3252796 LBA0337 Lactobacillus acidophilus NCFM hypothetical protein YP_193260.1 319080 R 272621 CDS YP_193261.1 58336676 3252797 319813..320571 1 NC_006814.3 transport protein; hypothetical protein 320571 3252797 LBA0338 Lactobacillus acidophilus NCFM hypothetical protein YP_193261.1 319813 D 272621 CDS YP_193262.1 58336677 3252802 320611..321291 1 NC_006814.3 COG0406 Fructose-2,6-bisphosphatase; phosphoglycerate mutase 321291 3252802 LBA0339 Lactobacillus acidophilus NCFM phosphoglycerate mutase YP_193262.1 320611 D 272621 CDS YP_193263.1 58336678 3252807 321353..322252 1 NC_006814.3 cation efflux protein 322252 3252807 LBA0340 Lactobacillus acidophilus NCFM cation efflux protein YP_193263.1 321353 D 272621 CDS YP_193264.1 58336679 3252808 322682..323122 1 NC_006814.3 COG0588 Phosphoglycerate mutase 1; pga mutase 323122 3252808 LBA0341 Lactobacillus acidophilus NCFM pga mutase YP_193264.1 322682 D 272621 CDS YP_193265.1 58336680 3252811 323227..324162 1 NC_006814.3 2',3'-cyclic-nucleotide 2'-phosphodiesterase 324162 3252811 LBA0342 Lactobacillus acidophilus NCFM 2',3'-cyclic-nucleotide 2'-phosphodiesterase YP_193265.1 323227 D 272621 CDS YP_193266.1 58336681 3252016 complement(324213..325562) 1 NC_006814.3 Aminopeptidase C (Bleomycin hydrolase); aminopeptidase 325562 3252016 LBA0343 Lactobacillus acidophilus NCFM aminopeptidase YP_193266.1 324213 R 272621 CDS YP_193267.1 58336682 3252828 complement(325633..325959) 1 NC_006814.3 CG9391-PA; hypothetical protein 325959 3252828 LBA0344 Lactobacillus acidophilus NCFM hypothetical protein YP_193267.1 325633 R 272621 CDS YP_193268.1 58336683 3252839 326061..326612 1 NC_006814.3 phage related protein; dUTPase 326612 3252839 LBA0345 Lactobacillus acidophilus NCFM dUTPase YP_193268.1 326061 D 272621 CDS YP_193269.1 58336684 3252017 326612..327988 1 NC_006814.3 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 327988 radA 3252017 radA Lactobacillus acidophilus NCFM DNA repair protein RadA YP_193269.1 326612 D 272621 CDS YP_193270.1 58336685 3252843 328066..329565 1 NC_006814.3 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 329565 gltX 3252843 gltX Lactobacillus acidophilus NCFM glutamyl-tRNA synthetase YP_193270.1 328066 D 272621 CDS YP_193271.1 58336686 3252846 329663..331096 1 NC_006814.3 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 331096 cysS 3252846 cysS Lactobacillus acidophilus NCFM cysteinyl-tRNA synthetase YP_193271.1 329663 D 272621 CDS YP_193272.1 58336687 3252020 331089..331532 1 NC_006814.3 hypothetical protein 331532 3252020 LBA0349 Lactobacillus acidophilus NCFM hypothetical protein YP_193272.1 331089 D 272621 CDS YP_193273.1 58336688 3252021 331519..332271 1 NC_006814.3 COG0566 rRNA methylases; tRNA-rRNA methyltransferase 332271 3252021 LBA0350 Lactobacillus acidophilus NCFM tRNA-rRNA methyltransferase YP_193273.1 331519 D 272621 CDS YP_193274.1 58336689 3252022 332411..332947 1 NC_006814.3 sigma factor 30 RNA polymerase 332947 3252022 LBA0351 Lactobacillus acidophilus NCFM sigma factor 30 RNA polymerase YP_193274.1 332411 D 272621 CDS YP_193275.1 58336690 3252856 333046..333264 1 NC_006814.3 hypothetical protein 333264 3252856 LBA0352 Lactobacillus acidophilus NCFM hypothetical protein YP_193275.1 333046 D 272621 CDS YP_193276.1 58336691 3252996 333403..334011 1 NC_006814.3 CG1644-PA; hypothetical protein 334011 3252996 LBA0353 Lactobacillus acidophilus NCFM hypothetical protein YP_193276.1 333403 D 272621 CDS YP_193277.1 58336692 3252034 334013..335497 1 NC_006814.3 gluconate kinase 335497 3252034 LBA0354 Lactobacillus acidophilus NCFM gluconate kinase YP_193277.1 334013 D 272621 CDS YP_193278.1 58336693 3252033 complement(335494..336375) 1 NC_006814.3 predicted protein; transcriptional regulator 336375 3252033 LBA0355 Lactobacillus acidophilus NCFM transcriptional regulator YP_193278.1 335494 R 272621 CDS YP_193279.1 58336694 3252032 complement(336498..338240) 1 NC_006814.3 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 338240 3252032 LBA0356 Lactobacillus acidophilus NCFM 1-deoxy-D-xylulose-5-phosphate synthase YP_193279.1 336498 R 272621 CDS YP_008992037.1 568886573 18111633 338428..338577 1 NC_006814.3 50S ribosomal protein L33 338577 18111633 LBA0357b Lactobacillus acidophilus NCFM 50S ribosomal protein L33 YP_008992037.1 338428 D 272621 CDS YP_193280.1 58336695 3252983 338586..338753 1 NC_006814.3 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 338753 secE 3252983 secE Lactobacillus acidophilus NCFM preprotein translocase subunit SecE YP_193280.1 338586 D 272621 CDS YP_193281.1 58336696 3252979 338867..339424 1 NC_006814.3 NusG; COG0250 transcriptional antiterminator; transcriptional antiterminator 339424 nusG 3252979 nusG Lactobacillus acidophilus NCFM transcriptional antiterminator YP_193281.1 338867 D 272621 CDS YP_193282.1 58336697 3252978 339551..339976 1 NC_006814.3 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 339976 rplK 3252978 rplK Lactobacillus acidophilus NCFM 50S ribosomal protein L11 YP_193282.1 339551 D 272621 CDS YP_193283.1 58336698 3252031 340056..340748 1 NC_006814.3 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 340748 rplA 3252031 rplA Lactobacillus acidophilus NCFM 50S ribosomal protein L1 YP_193283.1 340056 D 272621 CDS YP_193284.1 58336699 3252973 340852..341718 1 NC_006814.3 substrate binding protein; phosphate-binding protein; ABC transporter 341718 3252973 LBA0361 Lactobacillus acidophilus NCFM ABC transporter YP_193284.1 340852 D 272621 CDS YP_193285.1 58336700 3252030 341722..342717 1 NC_006814.3 ABC transporter permease 342717 3252030 LBA0362 Lactobacillus acidophilus NCFM ABC transporter permease YP_193285.1 341722 D 272621 CDS YP_193286.1 58336701 3252029 342720..343607 1 NC_006814.3 ABC transporter permease 343607 3252029 LBA0363 Lactobacillus acidophilus NCFM ABC transporter permease YP_193286.1 342720 D 272621 CDS YP_193287.1 58336702 3252968 343613..344410 1 NC_006814.3 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 344410 3252968 LBA0364 Lactobacillus acidophilus NCFM phosphate transporter ATP-binding protein YP_193287.1 343613 D 272621 CDS YP_193288.1 58336703 3252028 344412..345167 1 NC_006814.3 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate ABC transporter ATP-binding protein 345167 3252028 LBA0365 Lactobacillus acidophilus NCFM phosphate ABC transporter ATP-binding protein YP_193288.1 344412 D 272621 CDS YP_193289.1 58336704 3252027 345184..345861 1 NC_006814.3 PhoU; phosphate uptake regulator 345861 phoU 3252027 phoU Lactobacillus acidophilus NCFM phosphate uptake regulator YP_193289.1 345184 D 272621 CDS YP_193290.1 58336705 3252962 346044..347225 1 NC_006814.3 COG0679 Predicted permeases; receptor 347225 3252962 LBA0367 Lactobacillus acidophilus NCFM receptor YP_193290.1 346044 D 272621 CDS YP_193292.1 58336707 3253107 347907..348419 1 NC_006814.3 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 348419 rplJ 3253107 rplJ Lactobacillus acidophilus NCFM 50S ribosomal protein L10 YP_193292.1 347907 D 272621 CDS YP_193293.1 58336708 3252045 348469..348831 1 NC_006814.3 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 348831 rplL 3252045 rplL Lactobacillus acidophilus NCFM 50S ribosomal protein L7/L12 YP_193293.1 348469 D 272621 CDS YP_193294.1 58336709 3253044 348905..349720 1 NC_006814.3 K+ channel 349720 3253044 LBA0371 Lactobacillus acidophilus NCFM K+ channel YP_193294.1 348905 D 272621 CDS YP_193295.1 58336710 3252044 349754..350374 1 NC_006814.3 hypothetical protein 350374 3252044 LBA0373 Lactobacillus acidophilus NCFM hypothetical protein YP_193295.1 349754 D 272621 CDS YP_193296.1 58336711 3253036 350491..350745 1 NC_006814.3 protein Hepatitis C virus; hypothetical protein 350745 3253036 LBA0374 Lactobacillus acidophilus NCFM hypothetical protein YP_193296.1 350491 D 272621 CDS YP_193297.1 58336712 3253031 350778..351284 1 NC_006814.3 COG0590 Cytosine-adenosine deaminases; cytidine-deoxycytidylate deaminase 351284 3253031 LBA0375 Lactobacillus acidophilus NCFM cytidine-deoxycytidylate deaminase YP_193297.1 350778 D 272621 CDS YP_193298.1 58336713 3253026 351479..353269 1 NC_006814.3 DNA polymerase III (DNA directed ) gamma-tau 353269 3253026 LBA0376 Lactobacillus acidophilus NCFM DNA polymerase III (DNA directed ) gamma-tau YP_193298.1 351479 D 272621 CDS YP_193299.1 58336714 3252043 353447..354604 1 NC_006814.3 is605tnpB family; transposase 354604 tnpB 3252043 tnpB Lactobacillus acidophilus NCFM transposase YP_193299.1 353447 D 272621 CDS YP_193300.1 58336715 3252042 354802..355137 1 NC_006814.3 hypothetical protein 355137 3252042 LBA0378 Lactobacillus acidophilus NCFM hypothetical protein YP_193300.1 354802 D 272621 CDS YP_193301.1 58336716 3253016 355138..355737 1 NC_006814.3 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 355737 recR 3253016 recR Lactobacillus acidophilus NCFM recombination protein RecR YP_193301.1 355138 D 272621 CDS YP_193302.1 58336717 3252041 355737..355976 1 NC_006814.3 hypothetical protein 355976 3252041 LBA0380 Lactobacillus acidophilus NCFM hypothetical protein YP_193302.1 355737 D 272621 CDS YP_193303.1 58336718 3252040 356078..356728 1 NC_006814.3 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 356728 tmk 3252040 tmk Lactobacillus acidophilus NCFM thymidylate kinase YP_193303.1 356078 D 272621 CDS YP_193304.1 58336719 3253007 356729..357049 1 NC_006814.3 conserved protein lin2840; hypothetical protein 357049 3253007 LBA0382 Lactobacillus acidophilus NCFM hypothetical protein YP_193304.1 356729 D 272621 CDS YP_193305.1 58336720 3253005 357050..357907 1 NC_006814.3 DNA polymerase III subunit delta 357907 3253005 LBA0383 Lactobacillus acidophilus NCFM DNA polymerase III subunit delta YP_193305.1 357050 D 272621 CDS YP_193306.1 58336721 3253003 357919..358269 1 NC_006814.3 in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA; DNA replication intiation control protein YabA 358269 3253003 LBA0384 Lactobacillus acidophilus NCFM DNA replication intiation control protein YabA YP_193306.1 357919 D 272621 CDS YP_193307.1 58336722 3252038 358269..359123 1 NC_006814.3 COG0313 Predicted methyltransferases; tetrapyrrole methylase 359123 3252038 LBA0385 Lactobacillus acidophilus NCFM tetrapyrrole methylase YP_193307.1 358269 D 272621 CDS YP_193308.1 58336723 3252037 359126..359863 1 NC_006814.3 COG3884 Acyl-ACP thioesterase; acyl-ACP thioesterase 359863 3252037 LBA0386 Lactobacillus acidophilus NCFM acyl-ACP thioesterase YP_193308.1 359126 D 272621 CDS YP_193309.1 58336724 3252035 359893..360429 1 NC_006814.3 hypothetical protein 360429 3252035 LBA0387 Lactobacillus acidophilus NCFM hypothetical protein YP_193309.1 359893 D 272621 CDS YP_193310.1 58336725 3252264 360457..361191 1 NC_006814.3 glycoprotein endopeptidase 361191 3252264 LBA0388 Lactobacillus acidophilus NCFM glycoprotein endopeptidase YP_193310.1 360457 D 272621 CDS YP_193311.1 58336726 3252127 361175..361747 1 NC_006814.3 COG0456 Acetyltransferases; ribosomal protein ala-acetyltransferase 361747 3252127 LBA0389 Lactobacillus acidophilus NCFM ribosomal protein ala-acetyltransferase YP_193311.1 361175 D 272621 CDS YP_193312.1 58336727 3252119 361744..362793 1 NC_006814.3 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 362793 3252119 LBA0390 Lactobacillus acidophilus NCFM DNA-binding/iron metalloprotein/AP endonuclease YP_193312.1 361744 D 272621 CDS YP_193313.1 58336728 3252207 362931..363644 1 NC_006814.3 deoxyribose-phosphate aldolase; deoxyribose-p aldolase 363644 3252207 LBA0391 Lactobacillus acidophilus NCFM deoxyribose-p aldolase YP_193313.1 362931 D 272621 CDS YP_193314.1 58336729 3252399 363654..364625 1 NC_006814.3 dehydrogenase 364625 3252399 LBA0392 Lactobacillus acidophilus NCFM dehydrogenase YP_193314.1 363654 D 272621 CDS YP_193315.1 58336730 3252388 364618..365328 1 NC_006814.3 transcriptional regulator 365328 gntR 3252388 gntR Lactobacillus acidophilus NCFM transcriptional regulator YP_193315.1 364618 D 272621 CDS YP_193316.1 58336731 3252390 complement(365377..366564) 1 NC_006814.3 bile acid-inducible operon protein 366564 3252390 LBA0394 Lactobacillus acidophilus NCFM bile acid-inducible operon protein YP_193316.1 365377 R 272621 CDS YP_193317.1 58336732 3252347 complement(366636..367973) 1 NC_006814.3 catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA; formyl-coenzyme A transferase 367973 3252347 LBA0395 Lactobacillus acidophilus NCFM formyl-coenzyme A transferase YP_193317.1 366636 R 272621 CDS YP_193318.1 58336733 3252330 complement(367973..369682) 1 NC_006814.3 catalyzes the formation of formyl-CoA from oxalyl-CoA; oxalyl-CoA decarboxylase 369682 3252330 LBA0396 Lactobacillus acidophilus NCFM oxalyl-CoA decarboxylase YP_193318.1 367973 R 272621 CDS YP_193319.1 58336734 3252313 complement(369862..371781) 1 NC_006814.3 ATP binding protein; ABC transporter 371781 3252313 LBA0397 Lactobacillus acidophilus NCFM ABC transporter YP_193319.1 369862 R 272621 CDS YP_193320.1 58336735 3252544 371965..372600 1 NC_006814.3 modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor Rex 372600 3252544 LBA0398 Lactobacillus acidophilus NCFM redox-sensing transcriptional repressor Rex YP_193320.1 371965 D 272621 CDS YP_193321.1 58336736 3252547 complement(372648..373634) 1 NC_006814.3 sucrose operon transcriptional repressor; sucrose operon repressor 373634 scrR 3252547 scrR Lactobacillus acidophilus NCFM sucrose operon repressor YP_193321.1 372648 R 272621 CDS YP_193322.1 58336737 3252514 complement(373651..375108) 1 NC_006814.3 ScrB; sucrose hydrolase; sucrose-6-p hydrolase 375108 scrB 3252514 scrB Lactobacillus acidophilus NCFM sucrose-6-p hydrolase YP_193322.1 373651 R 272621 CDS YP_193323.1 58336738 3252638 375343..377292 1 NC_006814.3 sucrose PTS transporter; PTS system sucrose transporter subunit IIBCA 377292 scrA 3252638 scrA Lactobacillus acidophilus NCFM PTS system sucrose transporter subunit IIBCA YP_193323.1 375343 D 272621 CDS YP_193324.1 58336739 3252654 377384..377911 1 NC_006814.3 Penicillin-binding protein; hypothetical protein 377911 3252654 LBA0402 Lactobacillus acidophilus NCFM hypothetical protein YP_193324.1 377384 D 272621 CDS YP_193325.1 58336740 3252704 378008..378472 1 NC_006814.3 hypothetical protein 378472 3252704 LBA0403 Lactobacillus acidophilus NCFM hypothetical protein YP_193325.1 378008 D 272621 CDS YP_193326.1 58336741 3253095 378472..379230 1 NC_006814.3 hypothetical protein 379230 3253095 LBA0404 Lactobacillus acidophilus NCFM hypothetical protein YP_193326.1 378472 D 272621 CDS YP_193327.1 58336742 3252023 379398..379682 1 NC_006814.3 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 379682 groES 3252023 groES Lactobacillus acidophilus NCFM co-chaperonin GroES YP_193327.1 379398 D 272621 CDS YP_193328.1 58336743 3252952 379705..381333 1 NC_006814.3 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 381333 groEL 3252952 groEL Lactobacillus acidophilus NCFM molecular chaperone GroEL YP_193328.1 379705 D 272621 CDS YP_193329.1 58336744 3252208 381372..381503 1 NC_006814.3 hypothetical protein 381503 3252208 LBA0407 Lactobacillus acidophilus NCFM hypothetical protein YP_193329.1 381372 D 272621 CDS YP_193330.1 58336745 3252166 381484..384054 1 NC_006814.3 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 384054 hexA 3252166 hexA Lactobacillus acidophilus NCFM DNA mismatch repair protein MutS YP_193330.1 381484 D 272621 CDS YP_193331.1 58336746 3252169 384057..385952 1 NC_006814.3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 385952 mutL 3252169 mutL Lactobacillus acidophilus NCFM DNA mismatch repair protein YP_193331.1 384057 D 272621 CDS YP_193332.1 58336747 3252276 385952..386539 1 NC_006814.3 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 386539 ruvA 3252276 ruvA Lactobacillus acidophilus NCFM Holliday junction DNA helicase RuvA YP_193332.1 385952 D 272621 CDS YP_193333.1 58336748 3252834 386551..387600 1 NC_006814.3 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 387600 ruvB 3252834 ruvB Lactobacillus acidophilus NCFM Holliday junction DNA helicase RuvB YP_193333.1 386551 D 272621 CDS YP_193334.1 58336749 3252572 387650..388060 1 NC_006814.3 protein translocase 388060 3252572 LBA0412 Lactobacillus acidophilus NCFM protein translocase YP_193334.1 387650 D 272621 CDS YP_193335.1 58336750 3252289 388167..389618 1 NC_006814.3 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 389618 3252289 LBA0413 Lactobacillus acidophilus NCFM glucose-6-phosphate 1-dehydrogenase YP_193335.1 388167 D 272621 CDS YP_193336.1 58336751 3252943 389494..390732 1 NC_006814.3 DNA-damage-inducible protein 390732 3252943 LBA0414 Lactobacillus acidophilus NCFM DNA-damage-inducible protein YP_193336.1 389494 D 272621 CDS YP_193337.1 58336752 3252098 390795..391751 1 NC_006814.3 COG0618 Exopolyphosphatase-related protein; hypothetical protein 391751 3252098 LBA0415 Lactobacillus acidophilus NCFM hypothetical protein YP_193337.1 390795 D 272621 CDS YP_193338.1 58336753 3252462 391744..393105 1 NC_006814.3 RNA helicase 393105 3252462 LBA0416 Lactobacillus acidophilus NCFM RNA helicase YP_193338.1 391744 D 272621 CDS YP_193339.1 58336754 3252894 393347..395986 1 NC_006814.3 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 395986 alaS 3252894 alaS Lactobacillus acidophilus NCFM alanyl-tRNA synthetase YP_193339.1 393347 D 272621 CDS YP_193340.1 58336755 3252840 396047..396304 1 NC_006814.3 COG4472 Uncharacterized protein conserved in bacteria; hypothetical protein 396304 3252840 LBA0418 Lactobacillus acidophilus NCFM hypothetical protein YP_193340.1 396047 D 272621 CDS YP_193341.1 58336756 3252950 396304..396732 1 NC_006814.3 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 396732 3252950 LBA0419 Lactobacillus acidophilus NCFM Holliday junction resolvase-like protein YP_193341.1 396304 D 272621 CDS YP_193342.1 58336757 3252741 396734..397045 1 NC_006814.3 hypothetical protein 397045 3252741 LBA0420 Lactobacillus acidophilus NCFM hypothetical protein YP_193342.1 396734 D 272621 CDS YP_193343.1 58336758 3252461 397104..399461 1 NC_006814.3 MutS; mismatch repair protein 399461 mutS 3252461 mutS Lactobacillus acidophilus NCFM mismatch repair protein YP_193343.1 397104 D 272621 CDS YP_193344.1 58336759 3252140 399539..399850 1 NC_006814.3 thioredoxin reductase 399850 3252140 LBA0422 Lactobacillus acidophilus NCFM thioredoxin reductase YP_193344.1 399539 D 272621 CDS YP_193345.1 58336760 3252980 complement(399894..400268) 1 NC_006814.3 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 400268 mscL 3252980 mscL Lactobacillus acidophilus NCFM large-conductance mechanosensitive channel YP_193345.1 399894 R 272621 CDS YP_193346.1 58336761 3252573 complement(400374..400796) 1 NC_006814.3 hypothetical protein 400796 3252573 LBA0424 Lactobacillus acidophilus NCFM hypothetical protein YP_193346.1 400374 R 272621 CDS YP_193347.1 58336762 3252051 400874..401677 1 NC_006814.3 COG0796 Glutamate racemase; gluracemase 401677 murI 3252051 murI Lactobacillus acidophilus NCFM gluracemase YP_193347.1 400874 D 272621 CDS YP_193348.1 58336763 3252582 401677..402285 1 NC_006814.3 hydrolyzes non-standard nucleotides such as xanthine and inosine; nucleoside-triphosphatase 402285 3252582 LBA0426 Lactobacillus acidophilus NCFM nucleoside-triphosphatase YP_193348.1 401677 D 272621 CDS YP_193350.1 58336765 3252025 403294..403719 1 NC_006814.3 COG4768 Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain; tropomyosin-related protein 403719 3252025 LBA0428 Lactobacillus acidophilus NCFM tropomyosin-related protein YP_193350.1 403294 D 272621 CDS YP_193351.1 58336766 3252747 403737..404105 1 NC_006814.3 hypothetical protein 404105 3252747 LBA0429 Lactobacillus acidophilus NCFM hypothetical protein YP_193351.1 403737 D 272621 CDS YP_193352.1 58336767 3252976 complement(404158..405264) 1 NC_006814.3 Xaa-Pro dipeptidase (X-Pro dipeptidase) (Proline dipeptidase) (Prolidase) (Imidodipeptidase); Xaa-Pro dipeptidase 405264 3252976 LBA0430 Lactobacillus acidophilus NCFM Xaa-Pro dipeptidase YP_193352.1 404158 R 272621 CDS YP_193353.1 58336768 3252456 405409..406410 1 NC_006814.3 pepR1; catabolite control protein A 406410 ccpA 3252456 ccpA Lactobacillus acidophilus NCFM catabolite control protein A YP_193353.1 405409 D 272621 CDS YP_193354.1 58336769 3252886 complement(406445..407812) 1 NC_006814.3 COG0584 Glycerophosphoryl diester phosphodiesterase; glycerophosphoryl diester phosphodiesterase 407812 3252886 LBA0432 Lactobacillus acidophilus NCFM glycerophosphoryl diester phosphodiesterase YP_193354.1 406445 R 272621 CDS YP_193355.1 58336770 3252793 407908..408231 1 NC_006814.3 hypothetical protein 408231 3252793 LBA0433 Lactobacillus acidophilus NCFM hypothetical protein YP_193355.1 407908 D 272621 CDS YP_193356.1 58336771 3252265 408247..409629 1 NC_006814.3 UDP-sugar hydrolase 409629 3252265 LBA0434 Lactobacillus acidophilus NCFM UDP-sugar hydrolase YP_193356.1 408247 D 272621 CDS YP_193357.1 58336772 3252457 409562..410230 1 NC_006814.3 hypothetical protein 410230 3252457 LBA0435 Lactobacillus acidophilus NCFM hypothetical protein YP_193357.1 409562 D 272621 CDS YP_193358.1 58336773 3252283 410230..411006 1 NC_006814.3 n-acetylglucosamine catabolic protein 411006 3252283 LBA0436 Lactobacillus acidophilus NCFM n-acetylglucosamine catabolic protein YP_193358.1 410230 D 272621 CDS YP_193359.1 58336774 3252452 411003..411611 1 NC_006814.3 COG4478 Predicted membrane protein; hypothetical protein 411611 3252452 LBA0437 Lactobacillus acidophilus NCFM hypothetical protein YP_193359.1 411003 D 272621 CDS YP_193360.1 58336775 3252294 complement(411621..412271) 1 NC_006814.3 DedA; COG0586 Uncharacterized membrane-associated protein; hypothetical protein 412271 dedA 3252294 dedA Lactobacillus acidophilus NCFM hypothetical protein YP_193360.1 411621 R 272621 CDS YP_193361.1 58336776 3252969 complement(412281..413165) 1 NC_006814.3 COG0492 Thioredoxin reductase; thioredoxin reductase 413165 3252969 LBA0439 Lactobacillus acidophilus NCFM thioredoxin reductase YP_193361.1 412281 R 272621 CDS YP_193362.1 58336777 3252304 420438..420860 1 NC_006814.3 MutT; mutator protein 420860 mutT 3252304 mutT Lactobacillus acidophilus NCFM mutator protein YP_193362.1 420438 D 272621 CDS YP_193363.1 58336778 3252293 420860..423454 1 NC_006814.3 phage related helicase 423454 3252293 LBA0442 Lactobacillus acidophilus NCFM phage related helicase YP_193363.1 420860 D 272621 CDS YP_193364.1 58336779 3252855 423467..423751 1 NC_006814.3 helicase; hypothetical protein 423751 3252855 LBA0443 Lactobacillus acidophilus NCFM hypothetical protein YP_193364.1 423467 D 272621 CDS YP_193365.1 58336780 3253035 425058..426221 1 NC_006814.3 COG0438 Glycosyltransferase; glycosyltransferase 426221 3253035 LBA0444 Lactobacillus acidophilus NCFM glycosyltransferase YP_193365.1 425058 D 272621 CDS YP_193366.1 58336781 3252306 426236..427279 1 NC_006814.3 COG0438 Glycosyltransferase; glycosyltransferase 427279 3252306 LBA0445 Lactobacillus acidophilus NCFM glycosyltransferase YP_193366.1 426236 D 272621 CDS YP_193367.1 58336782 3252933 427279..428304 1 NC_006814.3 hypothetical protein 428304 3252933 LBA0446 Lactobacillus acidophilus NCFM hypothetical protein YP_193367.1 427279 D 272621 CDS YP_193368.1 58336783 3252893 428376..430436 1 NC_006814.3 phosphoglycerol transferase 430436 3252893 LBA0447 Lactobacillus acidophilus NCFM phosphoglycerol transferase YP_193368.1 428376 D 272621 CDS YP_193369.1 58336784 3252890 430504..430737 1 NC_006814.3 protein translocase, SecG subunit; preprotein translocase subunit SecG 430737 secG 3252890 secG Lactobacillus acidophilus NCFM preprotein translocase subunit SecG YP_193369.1 430504 D 272621 CDS YP_193370.1 58336785 3252853 430808..433156 1 NC_006814.3 COG0557 Exoribonuclease R; ribonuclease R 433156 3252853 LBA0449 Lactobacillus acidophilus NCFM ribonuclease R YP_193370.1 430808 D 272621 CDS YP_193371.1 58336786 3252940 433168..433623 1 NC_006814.3 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 433623 smpB 3252940 smpB Lactobacillus acidophilus NCFM SsrA-binding protein YP_193371.1 433168 D 272621 CDS YP_193372.1 58336787 3252133 439492..440502 1 NC_006814.3 PTS system mannose-specific transporter subunit IIAB 440502 manL 3252133 manL Lactobacillus acidophilus NCFM PTS system mannose-specific transporter subunit IIAB YP_193372.1 439492 D 272621 CDS YP_193373.1 58336788 3252117 440521..441330 1 NC_006814.3 COG3715 Phosphotransferase system, mannose-fructose -N-acetylgalactosamine-specific; PTS system mannose-specific transporter subunit IIC 441330 manM 3252117 manM Lactobacillus acidophilus NCFM PTS system mannose-specific transporter subunit IIC YP_193373.1 440521 D 272621 CDS YP_193374.1 58336789 3252804 441359..442282 1 NC_006814.3 COG3716 Phosphotransferase system, mannose-fructose -N-acetylgalactosamine-specific; PTS system mannose-specific transporter subunit IID 442282 manN 3252804 manN Lactobacillus acidophilus NCFM PTS system mannose-specific transporter subunit IID YP_193374.1 441359 D 272621 CDS YP_193375.1 58336790 3252879 442289..442657 1 NC_006814.3 hypothetical protein 442657 3252879 LBA0457 Lactobacillus acidophilus NCFM hypothetical protein YP_193375.1 442289 D 272621 CDS YP_193376.1 58336791 3252814 complement(442703..443584) 1 NC_006814.3 transcriptional regulator 443584 lysR 3252814 lysR Lactobacillus acidophilus NCFM transcriptional regulator YP_193376.1 442703 R 272621 CDS YP_193377.1 58336792 3252881 443767..444219 1 NC_006814.3 similar to acetyltransferase; maltose O-acetyltransferase 444219 3252881 LBA0459 Lactobacillus acidophilus NCFM maltose O-acetyltransferase YP_193377.1 443767 D 272621 CDS YP_193378.1 58336793 3252842 complement(444247..445620) 1 NC_006814.3 amino acid permease 445620 3252842 LBA0460 Lactobacillus acidophilus NCFM amino acid permease YP_193378.1 444247 R 272621 CDS YP_193379.1 58336794 3252921 445913..448543 1 NC_006814.3 COG1012 NAD-dependent aldehyde dehydrogenases; bifunctional acetaldehyde-CoA/alcohol dehydrogenase 448543 adhE 3252921 adhE Lactobacillus acidophilus NCFM bifunctional acetaldehyde-CoA/alcohol dehydrogenase YP_193379.1 445913 D 272621 CDS YP_193380.1 58336795 3252858 448725..450536 1 NC_006814.3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 450536 glmS 3252858 glmS Lactobacillus acidophilus NCFM glucosamine--fructose-6-phosphate aminotransferase YP_193380.1 448725 D 272621 CDS YP_193381.1 58336796 3252580 450871..452064 1 NC_006814.3 COG0282 Acetate kinase; acetate kinase 452064 ackA 3252580 ackA Lactobacillus acidophilus NCFM acetate kinase YP_193381.1 450871 D 272621 CDS YP_193382.1 58336797 3252803 452165..452896 1 NC_006814.3 carboxymuconolactone decarboxylase 452896 3252803 LBA0464 Lactobacillus acidophilus NCFM carboxymuconolactone decarboxylase YP_193382.1 452165 D 272621 CDS YP_193383.1 58336798 3252751 453002..453412 1 NC_006814.3 MutT; nudix family protein 453412 mutT 3252751 mutT Lactobacillus acidophilus NCFM nudix family protein YP_193383.1 453002 D 272621 CDS YP_193384.1 58336799 3252961 complement(453492..455150) 1 NC_006814.3 hypothetical protein 455150 3252961 LBA0466 Lactobacillus acidophilus NCFM hypothetical protein YP_193384.1 453492 R 272621 CDS YP_193385.1 58336800 3252551 455358..457178 1 NC_006814.3 hypothetical protein 457178 3252551 LBA0468 Lactobacillus acidophilus NCFM hypothetical protein YP_193385.1 455358 D 272621 CDS YP_193386.1 58336801 3252713 457183..458511 1 NC_006814.3 hypothetical protein 458511 3252713 LBA0469 Lactobacillus acidophilus NCFM hypothetical protein YP_193386.1 457183 D 272621 CDS YP_193387.1 58336802 3253046 458523..460754 1 NC_006814.3 COG1201 Lhr-like helicases; ATP-dependent helicase 460754 3253046 LBA0470 Lactobacillus acidophilus NCFM ATP-dependent helicase YP_193387.1 458523 D 272621 CDS YP_193388.1 58336803 3252722 460761..461165 1 NC_006814.3 Cytochrome P450 71C1; hypothetical protein 461165 3252722 LBA0471 Lactobacillus acidophilus NCFM hypothetical protein YP_193388.1 460761 D 272621 CDS YP_193389.1 58336804 3252557 461384..462634 1 NC_006814.3 ammonium transport protein; ammonium transporter 462634 amtB 3252557 amtB Lactobacillus acidophilus NCFM ammonium transporter YP_193389.1 461384 D 272621 CDS YP_193390.1 58336805 3252054 462687..463445 1 NC_006814.3 nitroreductase; NADPH-flavin oxidoreductase 463445 3252054 LBA0474 Lactobacillus acidophilus NCFM NADPH-flavin oxidoreductase YP_193390.1 462687 D 272621 CDS YP_193391.1 58336806 3252142 463844..468349 1 NC_006814.3 restriction endonuclease 468349 3252142 LBA0475 Lactobacillus acidophilus NCFM restriction endonuclease YP_193391.1 463844 D 272621 CDS YP_193392.1 58336807 3252096 468352..470100 1 NC_006814.3 prophage Lp2 protein 4; hypothetical protein 470100 3252096 LBA0476 Lactobacillus acidophilus NCFM hypothetical protein YP_193392.1 468352 D 272621 CDS YP_193393.1 58336808 3252301 470105..470974 1 NC_006814.3 prophage Lp2 protein 3; DNA methyltransferase 470974 3252301 LBA0477 Lactobacillus acidophilus NCFM DNA methyltransferase YP_193393.1 470105 D 272621 CDS YP_193394.1 58336809 3252272 471076..471759 1 NC_006814.3 methylase 471759 3252272 LBA0478 Lactobacillus acidophilus NCFM methylase YP_193394.1 471076 D 272621 CDS YP_193395.1 58336810 3252992 complement(471808..472509) 1 NC_006814.3 hypothetical protein 472509 3252992 LBA0479 Lactobacillus acidophilus NCFM hypothetical protein YP_193395.1 471808 R 272621 CDS YP_193396.1 58336811 3252255 472744..473094 1 NC_006814.3 hypothetical protein 473094 3252255 LBA0480 Lactobacillus acidophilus NCFM hypothetical protein YP_193396.1 472744 D 272621 CDS YP_193397.1 58336812 3252971 473261..474388 1 NC_006814.3 FtsK; hypothetical protein; DNA segregation ATPase 474388 ftsK 3252971 ftsK Lactobacillus acidophilus NCFM DNA segregation ATPase YP_193397.1 473261 D 272621 CDS YP_193398.1 58336813 3252467 474519..474932 1 NC_006814.3 hypothetical protein 474932 3252467 LBA0482 Lactobacillus acidophilus NCFM hypothetical protein YP_193398.1 474519 D 272621 CDS YP_193399.1 58336814 3252878 475046..476128 1 NC_006814.3 replication initiator protein 476128 repB 3252878 repB Lactobacillus acidophilus NCFM replication initiator protein YP_193399.1 475046 D 272621 CDS YP_193400.1 58336815 3252292 476393..477595 1 NC_006814.3 integrase 477595 3252292 LBA0484 Lactobacillus acidophilus NCFM integrase YP_193400.1 476393 D 272621 CDS YP_193401.1 58336816 3252930 477674..477814 1 NC_006814.3 hypothetical protein 477814 3252930 LBA0485 Lactobacillus acidophilus NCFM hypothetical protein YP_193401.1 477674 D 272621 CDS YP_193402.1 58336817 3252705 complement(477764..478159) 1 NC_006814.3 hypothetical protein 478159 3252705 LBA0486 Lactobacillus acidophilus NCFM hypothetical protein YP_193402.1 477764 R 272621 CDS YP_193403.1 58336818 3252136 complement(478246..478461) 1 NC_006814.3 hypothetical protein 478461 3252136 LBA0487 Lactobacillus acidophilus NCFM hypothetical protein YP_193403.1 478246 R 272621 CDS YP_193404.1 58336819 3252278 478565..478951 1 NC_006814.3 protein kinase; hypothetical protein 478951 3252278 LBA0488 Lactobacillus acidophilus NCFM hypothetical protein YP_193404.1 478565 D 272621 CDS YP_193405.1 58336820 3252749 478997..479866 1 NC_006814.3 serine-threonine protein phosphatase 479866 3252749 LBA0489 Lactobacillus acidophilus NCFM serine-threonine protein phosphatase YP_193405.1 478997 D 272621 CDS YP_193406.1 58336821 3252458 complement(479955..480071) 1 NC_006814.3 hypothetical protein 480071 3252458 LBA0490 Lactobacillus acidophilus NCFM hypothetical protein YP_193406.1 479955 R 272621 CDS YP_193407.1 58336822 3252567 480310..481647 1 NC_006814.3 cellobiose PTS, EIIC; PTS system cellobiose-specific transporter subunit IIC 481647 celB 3252567 celB Lactobacillus acidophilus NCFM PTS system cellobiose-specific transporter subunit IIC YP_193407.1 480310 D 272621 CDS YP_193408.1 58336823 3252137 481647..482540 1 NC_006814.3 hypothetical protein 482540 3252137 LBA0492 Lactobacillus acidophilus NCFM hypothetical protein YP_193408.1 481647 D 272621 CDS YP_193409.1 58336824 3252926 482878..483573 1 NC_006814.3 aggregation promoting factor; aggregation promoting protein 483573 3252926 LBA0493 Lactobacillus acidophilus NCFM aggregation promoting protein YP_193409.1 482878 D 272621 CDS YP_193410.1 58336825 3252646 483725..484792 1 NC_006814.3 surface exclusion protein 484792 3252646 LBA0494 Lactobacillus acidophilus NCFM surface exclusion protein YP_193410.1 483725 D 272621 CDS YP_193411.1 58336826 3252779 484817..485398 1 NC_006814.3 phosphoglycerate mutase 485398 3252779 LBA0495 Lactobacillus acidophilus NCFM phosphoglycerate mutase YP_193411.1 484817 D 272621 CDS YP_193412.1 58336827 3252906 485399..485971 1 NC_006814.3 phosphoglycerate mutase 485971 3252906 LBA0496 Lactobacillus acidophilus NCFM phosphoglycerate mutase YP_193412.1 485399 D 272621 CDS YP_193413.1 58336828 3252267 486057..486716 1 NC_006814.3 hypothetical protein 486716 3252267 LBA0497 Lactobacillus acidophilus NCFM hypothetical protein YP_193413.1 486057 D 272621 CDS YP_193414.1 58336829 3252288 486725..487024 1 NC_006814.3 glycerophosphoryl diester phosphodiesterase 487024 3252288 LBA0498 Lactobacillus acidophilus NCFM glycerophosphoryl diester phosphodiesterase YP_193414.1 486725 D 272621 CDS YP_193415.1 58336830 3252821 487489..488493 1 NC_006814.3 transcriptional repressor MsmR; msm operon repressor 488493 msmR 3252821 msmR Lactobacillus acidophilus NCFM msm operon repressor YP_193415.1 487489 D 272621 CDS YP_193416.1 58336831 3252767 488692..489987 1 NC_006814.3 MsmE; sugar ABC transporter substrate-binding protein 489987 msmE 3252767 msmE Lactobacillus acidophilus NCFM sugar ABC transporter substrate-binding protein YP_193416.1 488692 D 272621 CDS YP_193417.1 58336832 3252847 490008..490892 1 NC_006814.3 MsmF; ABC transporter permease 490892 msmF 3252847 msmF Lactobacillus acidophilus NCFM ABC transporter permease YP_193417.1 490008 D 272621 CDS YP_193418.1 58336833 3252194 490885..491742 1 NC_006814.3 MsmG; ABC transporter permease 491742 msmG 3252194 msmG Lactobacillus acidophilus NCFM ABC transporter permease YP_193418.1 490885 D 272621 CDS YP_193419.1 58336834 3252258 491742..493034 1 NC_006814.3 BfrA; fructosidase 493034 bfrA 3252258 bfrA Lactobacillus acidophilus NCFM fructosidase YP_193419.1 491742 D 272621 CDS YP_193420.1 58336835 3252909 493046..494152 1 NC_006814.3 MsmK; ABC transporter nucleotide binding protein 494152 msmK 3252909 msmK Lactobacillus acidophilus NCFM ABC transporter nucleotide binding protein YP_193420.1 493046 D 272621 CDS YP_193421.1 58336836 3252697 494279..495721 1 NC_006814.3 GtfA; sucrose phosphorylase 495721 gtfA 3252697 gtfA Lactobacillus acidophilus NCFM sucrose phosphorylase YP_193421.1 494279 D 272621 CDS YP_193422.1 58336837 3252226 496300..496809 1 NC_006814.3 hypothetical protein 496809 3252226 LBA0508 Lactobacillus acidophilus NCFM hypothetical protein YP_193422.1 496300 D 272621 CDS YP_193423.1 58336838 3252056 496739..496885 1 NC_006814.3 hypothetical protein 496885 3252056 LBA0509 Lactobacillus acidophilus NCFM hypothetical protein YP_193423.1 496739 D 272621 CDS YP_193424.1 58336839 3252798 497648..498691 1 NC_006814.3 PfoR; regulatory protein 498691 pfoR 3252798 pfoR Lactobacillus acidophilus NCFM regulatory protein YP_193424.1 497648 D 272621 CDS YP_193425.2 124388247 3253051 498965..500464 1 NC_006814.3 SlpX protein 500464 slpX 3253051 slpX Lactobacillus acidophilus NCFM SlpX protein YP_193425.2 498965 D 272621 CDS YP_193428.1 58336843 3252451 500981..502096 1 NC_006814.3 hypothetical protein 502096 3252451 LBA0515 Lactobacillus acidophilus NCFM hypothetical protein YP_193428.1 500981 D 272621 CDS YP_193429.1 58336844 3252233 502190..502891 1 NC_006814.3 transcriptional regulator 502891 gntR 3252233 gntR Lactobacillus acidophilus NCFM transcriptional regulator YP_193429.1 502190 D 272621 CDS YP_193430.1 58336845 3252869 complement(502927..503313) 1 NC_006814.3 COG0615 Cytidylyltransferase; glycerol-3-phosphate cytidyltransferase 503313 tagD 3252869 tagD Lactobacillus acidophilus NCFM glycerol-3-phosphate cytidyltransferase YP_193430.1 502927 R 272621 CDS YP_193431.1 58336846 3252450 503443..504171 1 NC_006814.3 UDP-N-acetyl-D-mannosamine transferase 504171 tagA 3252450 tagA Lactobacillus acidophilus NCFM UDP-N-acetyl-D-mannosamine transferase YP_193431.1 503443 D 272621 CDS YP_193432.1 58336847 3252564 504181..505272 1 NC_006814.3 COG0438 Glycosyltransferase; galactosyltransferase 505272 3252564 LBA0520 Lactobacillus acidophilus NCFM galactosyltransferase YP_193432.1 504181 D 272621 CDS YP_193433.1 58336848 3252506 505364..506842 1 NC_006814.3 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 506842 nadC 3252506 nadC Lactobacillus acidophilus NCFM nicotinate phosphoribosyltransferase YP_193433.1 505364 D 272621 CDS YP_193434.1 58336849 3252216 506839..507669 1 NC_006814.3 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 507669 nadE 3252216 nadE Lactobacillus acidophilus NCFM NAD synthetase YP_193434.1 506839 D 272621 CDS YP_193435.1 58336850 3252850 507861..510533 1 NC_006814.3 COG0474 Cation transport ATPase; cation-transporting P-type ATPase 510533 pacL 3252850 pacL Lactobacillus acidophilus NCFM cation-transporting P-type ATPase YP_193435.1 507861 D 272621 CDS YP_193436.1 58336851 3252568 510624..511778 1 NC_006814.3 COG1887 glycosyl-glycerophosphate transferases involved in teichoic acid biosynthesis TagF-TagB-EpsJ-RodC; teichoic acid biosynthesis protein 511778 rodC 3252568 rodC Lactobacillus acidophilus NCFM teichoic acid biosynthesis protein YP_193436.1 510624 D 272621 CDS YP_193437.1 58336852 3252128 511783..513213 1 NC_006814.3 capsular polysaccharide synthesis protein 513213 epsU 3252128 epsU Lactobacillus acidophilus NCFM capsular polysaccharide synthesis protein YP_193437.1 511783 D 272621 CDS YP_193438.1 58336853 3252619 513216..513914 1 NC_006814.3 CpsIVN; glycosyltransferase 513914 3252619 LBA0526 Lactobacillus acidophilus NCFM glycosyltransferase YP_193438.1 513216 D 272621 CDS YP_193439.1 58336854 3252211 514617..515264 1 NC_006814.3 COG1705 Muramidase (flagellum-specific); N-acetylmuramidase 515264 acmA 3252211 acmA Lactobacillus acidophilus NCFM N-acetylmuramidase YP_193439.1 514617 D 272621 CDS YP_193440.1 58336855 3252189 515352..517592 1 NC_006814.3 ATP-dependent helicase 517592 pcrA 3252189 pcrA Lactobacillus acidophilus NCFM ATP-dependent helicase YP_193440.1 515352 D 272621 CDS YP_193441.1 58336856 3252290 517625..519631 1 NC_006814.3 DNA ligase 519631 dnlJ 3252290 dnlJ Lactobacillus acidophilus NCFM DNA ligase YP_193441.1 517625 D 272621 CDS YP_193442.1 58336857 3252912 519646..520794 1 NC_006814.3 hypothetical protein 520794 3252912 LBA0530 Lactobacillus acidophilus NCFM hypothetical protein YP_193442.1 519646 D 272621 CDS YP_193443.1 58336858 3252659 520806..521114 1 NC_006814.3 Glu-tRNA(Gln) amidotransferase subunit C 521114 gatC 3252659 gatC Lactobacillus acidophilus NCFM Glu-tRNA(Gln) amidotransferase subunit C YP_193443.1 520806 D 272621 CDS YP_193444.1 58336859 3252297 521114..522553 1 NC_006814.3 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 522553 gatA 3252297 gatA Lactobacillus acidophilus NCFM aspartyl/glutamyl-tRNA amidotransferase subunit A YP_193444.1 521114 D 272621 CDS YP_193445.1 58336860 3253001 522558..523988 1 NC_006814.3 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 523988 gatB 3253001 gatB Lactobacillus acidophilus NCFM aspartyl/glutamyl-tRNA amidotransferase subunit B YP_193445.1 522558 D 272621 CDS YP_193446.1 58336861 3252262 524014..524934 1 NC_006814.3 similar to YegS from E. coli; lipid kinase 524934 3252262 LBA0534 Lactobacillus acidophilus NCFM lipid kinase YP_193446.1 524014 D 272621 CDS YP_193449.1 58336864 3252739 525852..526193 1 NC_006814.3 serpin (40.6 kD) (srp-3); hypothetical protein 526193 3252739 LBA0537 Lactobacillus acidophilus NCFM hypothetical protein YP_193449.1 525852 D 272621 CDS YP_193450.1 58336865 3252201 complement(526229..527605) 1 NC_006814.3 Na(+)-H(+) antiporter; Na+-H+-exchanging protein 527605 3252201 LBA0538 Lactobacillus acidophilus NCFM Na+-H+-exchanging protein YP_193450.1 526229 R 272621 CDS YP_193451.1 58336866 3252768 527971..529323 1 NC_006814.3 RNA methyltransferase 529323 3252768 LBA0539 Lactobacillus acidophilus NCFM RNA methyltransferase YP_193451.1 527971 D 272621 CDS YP_193452.1 58336867 3252113 529805..530209 1 NC_006814.3 hypothetical protein 530209 3252113 LBA0540 Lactobacillus acidophilus NCFM hypothetical protein YP_193452.1 529805 D 272621 CDS YP_193453.1 58336868 3253034 530433..532334 1 NC_006814.3 potential frameshift to 542; CadA; COG2217 Cation transport ATPase; cadmium-transporting ATPase 532334 cadA 3253034 cadA Lactobacillus acidophilus NCFM cadmium-transporting ATPase YP_193453.1 530433 D 272621 CDS YP_193454.1 58336869 3252352 532360..532590 1 NC_006814.3 potential frameshift to 541; COG2608 Copper chaperone; heavy-metal-transporting ATPase 532590 3252352 LBA0542 Lactobacillus acidophilus NCFM heavy-metal-transporting ATPase YP_193454.1 532360 D 272621 CDS YP_193455.1 58336870 3253010 532590..533132 1 NC_006814.3 hypothetical protein 533132 3253010 LBA0543 Lactobacillus acidophilus NCFM hypothetical protein YP_193455.1 532590 D 272621 CDS YP_193456.1 58336871 3252395 533152..533787 1 NC_006814.3 COG0664 cAMP-binding protein -catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases; transcriptional regulator 533787 3252395 LBA0544 Lactobacillus acidophilus NCFM transcriptional regulator YP_193456.1 533152 D 272621 CDS YP_193457.1 58336872 3252053 533869..534456 1 NC_006814.3 COG1573 Uracil-DNA glycosylase; hypothetical protein 534456 3252053 LBA0545 Lactobacillus acidophilus NCFM hypothetical protein YP_193457.1 533869 D 272621 CDS YP_193459.1 58336874 3252851 complement(535200..536216) 1 NC_006814.3 potential frameshift to 548; site-specific recombinase 536216 3252851 LBA0547 Lactobacillus acidophilus NCFM site-specific recombinase YP_193459.1 535200 R 272621 CDS YP_193460.1 58336875 3252268 complement(536234..536767) 1 NC_006814.3 potential frameshift to 547; site-specific recombinase 536767 3252268 LBA0548 Lactobacillus acidophilus NCFM site-specific recombinase YP_193460.1 536234 R 272621 CDS YP_193461.1 58336876 3252737 complement(536760..537689) 1 NC_006814.3 potential frameshift to 548; site-specific recombinase 537689 3252737 LBA0549 Lactobacillus acidophilus NCFM site-specific recombinase YP_193461.1 536760 R 272621 CDS YP_193462.1 58336877 3252903 complement(537721..538053) 1 NC_006814.3 COG4695 Phage-related protein; portal protein 538053 3252903 LBA0550 Lactobacillus acidophilus NCFM portal protein YP_193462.1 537721 R 272621 CDS YP_193463.1 58336878 3252561 538338..538838 1 NC_006814.3 conserved hypothetical protein; acetyltransferase 538838 3252561 LBA0551 Lactobacillus acidophilus NCFM acetyltransferase YP_193463.1 538338 D 272621 CDS YP_193464.1 58336879 3252686 539329..540795 1 NC_006814.3 multidrug transporter 540795 3252686 LBA0552 Lactobacillus acidophilus NCFM multidrug transporter YP_193464.1 539329 D 272621 CDS YP_193465.1 58336880 3252831 complement(540836..541594) 1 NC_006814.3 PlnI; hypothetical protein 541594 plnI 3252831 plnI Lactobacillus acidophilus NCFM hypothetical protein YP_193465.1 540836 R 272621 CDS YP_193466.1 58336881 3253022 complement(541605..542117) 1 NC_006814.3 COG1309 transcriptional regulator; transcriptional regulator 542117 3253022 LBA0554 Lactobacillus acidophilus NCFM transcriptional regulator YP_193466.1 541605 R 272621 CDS YP_193467.1 58336882 3252089 542226..543998 1 NC_006814.3 in group A Streptococci this protein was found to cross react with anti myosin antibodies and may play a role in rheumatic fever; hypothetical protein 543998 3252089 LBA0555 Lactobacillus acidophilus NCFM hypothetical protein YP_193467.1 542226 D 272621 CDS YP_193468.1 58336883 3253039 544625..545062 1 NC_006814.3 potential frameshift to 557; hypothetical protein; acetyltransferase 545062 3253039 LBA0556 Lactobacillus acidophilus NCFM acetyltransferase YP_193468.1 544625 D 272621 CDS YP_193469.1 58336884 3252221 545031..545141 1 NC_006814.3 hypothetical protein 545141 3252221 LBA0557 Lactobacillus acidophilus NCFM hypothetical protein YP_193469.1 545031 D 272621 CDS YP_193470.1 58336885 3252873 545265..546101 1 NC_006814.3 aldehyde reductase 546101 3252873 LBA0558 Lactobacillus acidophilus NCFM aldehyde reductase YP_193470.1 545265 D 272621 CDS YP_193471.1 58336886 3253040 546284..546943 1 NC_006814.3 potential frameshift to 560; ABC transporter ATP-binding protein/permease component 546943 3253040 LBA0559 Lactobacillus acidophilus NCFM ABC transporter ATP-binding protein/permease component YP_193471.1 546284 D 272621 CDS YP_193472.1 58336887 3252577 546980..547714 1 NC_006814.3 potential frameshift to 559; ABC transporter ATP-binding protein/permease component 547714 3252577 LBA0560 Lactobacillus acidophilus NCFM ABC transporter ATP-binding protein/permease component YP_193472.1 546980 D 272621 CDS YP_193473.1 58336888 3252994 547777..547872 1 NC_006814.3 hypothetical protein 547872 3252994 LBA0561 Lactobacillus acidophilus NCFM hypothetical protein YP_193473.1 547777 D 272621 CDS YP_193474.1 58336889 3252947 complement(547922..549256) 1 NC_006814.3 COG2233 Xanthine-uracil permeases; uracil permease 549256 3252947 LBA0562 Lactobacillus acidophilus NCFM uracil permease YP_193474.1 547922 R 272621 CDS YP_193475.1 58336890 3252900 complement(549268..549798) 1 NC_006814.3 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase 549798 pyrR 3252900 pyrR Lactobacillus acidophilus NCFM bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase YP_193475.1 549268 R 272621 CDS YP_193476.1 58336891 3253032 complement(550000..550422) 1 NC_006814.3 potential frameshift to 565; HAD family hydrolase 550422 3253032 LBA0564 Lactobacillus acidophilus NCFM HAD family hydrolase YP_193476.1 550000 R 272621 CDS YP_193477.1 58336892 3252951 complement(550479..550790) 1 NC_006814.3 potential frameshift to 564; COG0561 Predicted hydrolases of the HAD superfamily; HAD family hydrolase 550790 3252951 LBA0565 Lactobacillus acidophilus NCFM HAD family hydrolase YP_193477.1 550479 R 272621 CDS YP_193478.1 58336893 3253037 550972..552387 1 NC_006814.3 multidrug transporter 552387 3253037 LBA0566 Lactobacillus acidophilus NCFM multidrug transporter YP_193478.1 550972 D 272621 CDS YP_193479.1 58336894 3252270 complement(552410..553615) 1 NC_006814.3 multidrug resistance efflux pump 553615 3252270 LBA0567 Lactobacillus acidophilus NCFM multidrug resistance efflux pump YP_193479.1 552410 R 272621 CDS YP_193480.1 58336895 3253038 553716..554654 1 NC_006814.3 COG0679 Predicted permeases; malate permease 554654 3253038 LBA0568 Lactobacillus acidophilus NCFM malate permease YP_193480.1 553716 D 272621 CDS YP_193481.1 58336896 3253042 554691..555773 1 NC_006814.3 peptidase, M42 family; aminopeptidase 555773 3253042 LBA0569 Lactobacillus acidophilus NCFM aminopeptidase YP_193481.1 554691 D 272621 CDS YP_193482.1 58336897 3252852 555867..557492 1 NC_006814.3 ABC transporter ATP-binding protein 557492 3252852 LBA0570 Lactobacillus acidophilus NCFM ABC transporter ATP-binding protein YP_193482.1 555867 D 272621 CDS YP_193483.1 58336898 3253021 557591..558367 1 NC_006814.3 Type II restriction enzyme HgiEI (Endonuclease HgiEI) (R.HgiEI); hypothetical protein 558367 3253021 LBA0571 Lactobacillus acidophilus NCFM hypothetical protein YP_193483.1 557591 D 272621 CDS YP_193484.1 58336899 3253023 complement(558432..559250) 1 NC_006814.3 glutaminebinding protein; glutamine ABC transporter 559250 glnH 3253023 glnH Lactobacillus acidophilus NCFM glutamine ABC transporter YP_193484.1 558432 R 272621 CDS YP_193485.1 58336900 3253033 559448..559891 1 NC_006814.3 transcriptional regulator 559891 3253033 LBA0573 Lactobacillus acidophilus NCFM transcriptional regulator YP_193485.1 559448 D 272621 CDS YP_193486.1 58336901 3253020 559891..561621 1 NC_006814.3 ABC transporter ATP-binding protein/permease 561621 3253020 LBA0574 Lactobacillus acidophilus NCFM ABC transporter ATP-binding protein/permease YP_193486.1 559891 D 272621 CDS YP_193487.1 58336902 3252990 561621..563390 1 NC_006814.3 ABC transporter ATP-binding protein/permease 563390 3252990 LBA0575 Lactobacillus acidophilus NCFM ABC transporter ATP-binding protein/permease YP_193487.1 561621 D 272621 CDS YP_193488.1 58336903 3252375 563558..564136 1 NC_006814.3 hypothetical protein 564136 3252375 LBA0576 Lactobacillus acidophilus NCFM hypothetical protein YP_193488.1 563558 D 272621 CDS YP_193489.1 58336904 3252867 complement(564181..564810) 1 NC_006814.3 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 564810 3252867 LBA0577 Lactobacillus acidophilus NCFM uridine kinase YP_193489.1 564181 R 272621 CDS YP_193490.1 58336905 3252870 565475..566215 1 NC_006814.3 GlnQ; glutamine ABC transporter ATP-binding protein 566215 glnQ 3252870 glnQ Lactobacillus acidophilus NCFM glutamine ABC transporter ATP-binding protein YP_193490.1 565475 D 272621 CDS YP_193491.1 58336906 3252954 566229..567047 1 NC_006814.3 GlnH; glutamine-binding protein 567047 glnH 3252954 glnH Lactobacillus acidophilus NCFM glutamine-binding protein YP_193491.1 566229 D 272621 CDS YP_193492.1 58336907 3252770 567047..567688 1 NC_006814.3 GlnM; glutamine ABC transporter permease 567688 glnM 3252770 glnM Lactobacillus acidophilus NCFM glutamine ABC transporter permease YP_193492.1 567047 D 272621 CDS YP_193493.1 58336908 3252345 567703..568359 1 NC_006814.3 GlnP; glutamine ABC transporter membrane protein 568359 glnP 3252345 glnP Lactobacillus acidophilus NCFM glutamine ABC transporter membrane protein YP_193493.1 567703 D 272621 CDS YP_193494.1 58336909 3252656 568438..569358 1 NC_006814.3 similar to lmo2804; hypothetical protein 569358 3252656 LBA0583 Lactobacillus acidophilus NCFM hypothetical protein YP_193494.1 568438 D 272621 CDS YP_193495.1 58336910 3252077 569355..569798 1 NC_006814.3 COG2966 Uncharacterized conserved protein; hypothetical protein 569798 3252077 LBA0584 Lactobacillus acidophilus NCFM hypothetical protein YP_193495.1 569355 D 272621 CDS YP_193496.1 58336911 3252466 complement(569961..571259) 1 NC_006814.3 glycerol-3-phosphate ABC transporter 571259 3252466 LBA0585 Lactobacillus acidophilus NCFM glycerol-3-phosphate ABC transporter YP_193496.1 569961 R 272621 CDS YP_193497.1 58336912 3252220 571419..572222 1 NC_006814.3 COG1085 Galactose-1-phosphate uridylyltransferase; galactose-1-phosphate uridylyltransferase 572222 3252220 LBA0586 Lactobacillus acidophilus NCFM galactose-1-phosphate uridylyltransferase YP_193497.1 571419 D 272621 CDS YP_193498.1 58336913 3252857 572309..573232 1 NC_006814.3 RbsK; ribokinase 573232 rbsK 3252857 rbsK Lactobacillus acidophilus NCFM ribokinase YP_193498.1 572309 D 272621 CDS YP_193499.1 58336914 3252540 573233..573925 1 NC_006814.3 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 573925 rpiA 3252540 rpiA Lactobacillus acidophilus NCFM ribose-5-phosphate isomerase A YP_193499.1 573233 D 272621 CDS YP_193500.1 58336915 3252078 574077..576092 1 NC_006814.3 COG3158 K+ transporter; potassium uptake protein Kup 576092 3252078 LBA0590 Lactobacillus acidophilus NCFM potassium uptake protein Kup YP_193500.1 574077 D 272621 CDS YP_193501.1 58336916 3252100 576206..577132 1 NC_006814.3 COG1957 Inosine-uridine nucleoside N-ribohydrolase; nucleoside hydrolase 577132 iunH 3252100 iunH Lactobacillus acidophilus NCFM nucleoside hydrolase YP_193501.1 576206 D 272621 CDS YP_193502.1 58336917 3252370 577135..577860 1 NC_006814.3 transcriptional regulator 577860 gntR 3252370 gntR Lactobacillus acidophilus NCFM transcriptional regulator YP_193502.1 577135 D 272621 CDS YP_193503.1 58336918 3252639 578166..578798 1 NC_006814.3 COG1396 Predicted transcriptional regulators; transcriptional regulator 578798 3252639 LBA0593 Lactobacillus acidophilus NCFM transcriptional regulator YP_193503.1 578166 D 272621 CDS YP_193504.1 58336919 3252361 578842..580458 1 NC_006814.3 ABC transporter ATP-binding protein 580458 3252361 LBA0594 Lactobacillus acidophilus NCFM ABC transporter ATP-binding protein YP_193504.1 578842 D 272621 CDS YP_193505.1 58336920 3252884 complement(580503..581321) 1 NC_006814.3 hypothetical protein 581321 3252884 LBA0595 Lactobacillus acidophilus NCFM hypothetical protein YP_193505.1 580503 R 272621 CDS YP_193506.1 58336921 3252584 581451..581891 1 NC_006814.3 COG1846 transcriptional regulators; transcriptional regulator 581891 marR 3252584 marR Lactobacillus acidophilus NCFM transcriptional regulator YP_193506.1 581451 D 272621 CDS YP_193507.1 58336922 3252555 581970..583727 1 NC_006814.3 multidrug resistance ABC transporter ATP binding protein 583727 3252555 LBA0597 Lactobacillus acidophilus NCFM multidrug resistance ABC transporter ATP binding protein YP_193507.1 581970 D 272621 CDS YP_193508.1 58336923 3252914 complement(583832..584188) 1 NC_006814.3 hypothetical protein 584188 3252914 LBA0598 Lactobacillus acidophilus NCFM hypothetical protein YP_193508.1 583832 R 272621 CDS YP_193509.1 58336924 3252709 complement(584194..584958) 1 NC_006814.3 transcriptional regulator 584958 3252709 LBA0599 Lactobacillus acidophilus NCFM transcriptional regulator YP_193509.1 584194 R 272621 CDS YP_193510.1 58336925 3253004 585252..587651 1 NC_006814.3 phosphoketolase 587651 3253004 LBA0600 Lactobacillus acidophilus NCFM phosphoketolase YP_193510.1 585252 D 272621 CDS YP_193511.1 58336926 3252379 587713..588561 1 NC_006814.3 serine protease 588561 3252379 LBA0601 Lactobacillus acidophilus NCFM serine protease YP_193511.1 587713 D 272621 CDS YP_193512.1 58336927 3252944 588692..589972 1 NC_006814.3 bacteriocin production-related histidine kinase 589972 3252944 LBA0602 Lactobacillus acidophilus NCFM bacteriocin production-related histidine kinase YP_193512.1 588692 D 272621 CDS YP_193513.1 58336928 3253043 589978..590775 1 NC_006814.3 AbpR; response regulator bacteriocinproduction-related 590775 3253043 LBA0603 Lactobacillus acidophilus NCFM response regulator bacteriocinproduction-related YP_193513.1 589978 D 272621 CDS YP_193514.1 58336929 3252795 590842..592050 1 NC_006814.3 PlnI; immunity protein 592050 plnI 3252795 plnI Lactobacillus acidophilus NCFM immunity protein YP_193514.1 590842 D 272621 CDS YP_193515.1 58336930 3252991 complement(592203..593012) 1 NC_006814.3 hydrolase 593012 3252991 LBA0605 Lactobacillus acidophilus NCFM hydrolase YP_193515.1 592203 R 272621 CDS YP_193516.1 58336931 3252644 593543..595423 1 NC_006814.3 PTS system arbutin-like transporter subunit IIBC 595423 3252644 LBA0606 Lactobacillus acidophilus NCFM PTS system arbutin-like transporter subunit IIBC YP_193516.1 593543 D 272621 CDS YP_193517.1 58336932 3252430 595485..596297 1 NC_006814.3 similar to hypothetical protein; transcriptional regulator 596297 3252430 LBA0607 Lactobacillus acidophilus NCFM transcriptional regulator YP_193517.1 595485 D 272621 CDS YP_193518.1 58336933 3252929 596281..596778 1 NC_006814.3 transporter accessory protein; hypothetical protein 596778 3252929 LBA0608 Lactobacillus acidophilus NCFM hypothetical protein YP_193518.1 596281 D 272621 CDS YP_193519.1 58336934 3252407 596799..597284 1 NC_006814.3 PTS system transporter subunit IIABC 597284 3252407 LBA0609 Lactobacillus acidophilus NCFM PTS system transporter subunit IIABC YP_193519.1 596799 D 272621 CDS YP_193520.1 58336935 3253052 597409..597675 1 NC_006814.3 hypothetical protein 597675 3253052 LBA0610 Lactobacillus acidophilus NCFM hypothetical protein YP_193520.1 597409 D 272621 CDS YP_193521.1 58336936 3253112 597710..598366 1 NC_006814.3 COG0778 Nitroreductase; nitroreductase 598366 3253112 LBA0611 Lactobacillus acidophilus NCFM nitroreductase YP_193521.1 597710 D 272621 CDS YP_193522.1 58336937 3253000 598461..599813 1 NC_006814.3 transporter 599813 3253000 LBA0612 Lactobacillus acidophilus NCFM transporter YP_193522.1 598461 D 272621 CDS YP_193523.1 58336938 3252891 599922..600491 1 NC_006814.3 COG0634 Hypoxanthine-guanine phosphoribosyltransferase; hypothetical protein 600491 hprT 3252891 hprT Lactobacillus acidophilus NCFM hypothetical protein YP_193523.1 599922 D 272621 CDS YP_193524.1 58336939 3252680 complement(600545..601927) 1 NC_006814.3 transposase 601927 3252680 LBA0614 Lactobacillus acidophilus NCFM transposase YP_193524.1 600545 R 272621 CDS YP_193525.1 58336940 3252738 complement(601981..603285) 1 NC_006814.3 COG0531 Amino acid transporters; amino acid permease 603285 3252738 LBA0615 Lactobacillus acidophilus NCFM amino acid permease YP_193525.1 601981 R 272621 CDS YP_193526.1 58336941 3252728 603391..604095 1 NC_006814.3 COG3757 Lyzozyme M1 (1,4-beta-N-acetylmuramidase); hypothetical protein 604095 3252728 LBA0616 Lactobacillus acidophilus NCFM hypothetical protein YP_193526.1 603391 D 272621 CDS YP_193527.1 58336942 3252298 604095..605333 1 NC_006814.3 ATP-dependent RNA helicase 605333 3252298 LBA0617 Lactobacillus acidophilus NCFM ATP-dependent RNA helicase YP_193527.1 604095 D 272621 CDS YP_193528.1 58336943 3252132 605330..606655 1 NC_006814.3 PTS system cellobiose-specific transporter subunit IIC 606655 ptcC 3252132 ptcC Lactobacillus acidophilus NCFM PTS system cellobiose-specific transporter subunit IIC YP_193528.1 605330 D 272621 CDS YP_193529.1 58336944 3252818 606973..607077 1 NC_006814.3 hypothetical protein 607077 3252818 LBA0619 Lactobacillus acidophilus NCFM hypothetical protein YP_193529.1 606973 D 272621 CDS YP_193530.1 58336945 3252445 607121..608263 1 NC_006814.3 potential frameshift to 619; UDP-N-acetylglucosamine 2-epimerase 608263 3252445 LBA0620 Lactobacillus acidophilus NCFM UDP-N-acetylglucosamine 2-epimerase YP_193530.1 607121 D 272621 CDS YP_193531.1 58336946 3252106 complement(608276..608800) 1 NC_006814.3 GtcA; cellwall teichoic acid glycosylation protein 608800 gtcA 3252106 gtcA Lactobacillus acidophilus NCFM cellwall teichoic acid glycosylation protein YP_193531.1 608276 R 272621 CDS YP_193532.1 58336947 3252815 complement(608793..609239) 1 NC_006814.3 COG0716 Flavodoxins; flavodoxin 609239 3252815 LBA0622 Lactobacillus acidophilus NCFM flavodoxin YP_193532.1 608793 R 272621 CDS YP_193533.1 58336948 3252504 609383..610210 1 NC_006814.3 AmpM; COG0024 Methionine aminopeptidase; methionine aminopeptidase 610210 ampM 3252504 ampM Lactobacillus acidophilus NCFM methionine aminopeptidase YP_193533.1 609383 D 272621 CDS YP_193534.1 58336949 3252062 610219..611145 1 NC_006814.3 COG1295 Predicted membrane protein; hypothetical protein 611145 3252062 LBA0624 Lactobacillus acidophilus NCFM hypothetical protein YP_193534.1 610219 D 272621 CDS YP_193535.1 58336950 3253049 611205..612107 1 NC_006814.3 COG1210 UDP-glucose pyrophosphorylase; UTP-glucose-1-phosphate uridylyltransferase 612107 3253049 LBA0625 Lactobacillus acidophilus NCFM UTP-glucose-1-phosphate uridylyltransferase YP_193535.1 611205 D 272621 CDS YP_193536.1 58336951 3252766 612217..613374 1 NC_006814.3 COG0183 Acetyl-CoA acetyltransferase; acetyl-CoA C-acetyltransferase thil 613374 thil 3252766 thil Lactobacillus acidophilus NCFM acetyl-CoA C-acetyltransferase thil YP_193536.1 612217 D 272621 CDS YP_193537.1 58336952 3252708 613374..614585 1 NC_006814.3 HmdH; COG1257 Hydroxymethylglutaryl-CoA reductase; hydroxymethylglutaryl-CoA reductase 614585 hmdH 3252708 hmdH Lactobacillus acidophilus NCFM hydroxymethylglutaryl-CoA reductase YP_193537.1 613374 D 272621 CDS YP_193538.1 58336953 3252698 614586..615749 1 NC_006814.3 HmcS; COG3425 3-hydroxy-3-methylglutaryl CoA synthase; hydroxymethylglutaryl-CoA synthase 615749 hmcS 3252698 hmcS Lactobacillus acidophilus NCFM hydroxymethylglutaryl-CoA synthase YP_193538.1 614586 D 272621 CDS YP_193539.1 58336954 3252756 complement(615784..616110) 1 NC_006814.3 GcpE protein; hypothetical protein 616110 3252756 LBA0629 Lactobacillus acidophilus NCFM hypothetical protein YP_193539.1 615784 R 272621 CDS YP_193540.1 58336955 3252777 616202..617119 1 NC_006814.3 hypothetical protein 617119 3252777 LBA0630 Lactobacillus acidophilus NCFM hypothetical protein YP_193540.1 616202 D 272621 CDS YP_193541.1 58336956 3252759 617353..617457 1 NC_006814.3 hypothetical protein 617457 3252759 LBA0631 Lactobacillus acidophilus NCFM hypothetical protein YP_193541.1 617353 D 272621 CDS YP_193542.1 58336957 3252468 complement(617543..618925) 1 NC_006814.3 TrmA; RNA methyltransferase 618925 3252468 LBA0632 Lactobacillus acidophilus NCFM RNA methyltransferase YP_193542.1 617543 R 272621 CDS YP_193543.1 58336958 3252162 619051..619863 1 NC_006814.3 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 619863 recX 3252162 recX Lactobacillus acidophilus NCFM recombination regulator RecX YP_193543.1 619051 D 272621 CDS YP_193544.1 58336959 3252892 619873..620349 1 NC_006814.3 hypothetical protein 620349 3252892 LBA0634 Lactobacillus acidophilus NCFM hypothetical protein YP_193544.1 619873 D 272621 CDS YP_193545.1 58336960 3252186 620918..621781 1 NC_006814.3 transporter protein - hemolysin 621781 3252186 LBA0635 Lactobacillus acidophilus NCFM transporter protein - hemolysin YP_193545.1 620918 D 272621 CDS YP_193546.1 58336961 3253098 621781..623352 1 NC_006814.3 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 623352 prfC 3253098 prfC Lactobacillus acidophilus NCFM peptide chain release factor 3 YP_193546.1 621781 D 272621 CDS YP_193547.1 58336962 3252824 complement(623417..623698) 1 NC_006814.3 hypothetical protein 623698 3252824 LBA0637 Lactobacillus acidophilus NCFM hypothetical protein YP_193547.1 623417 R 272621 CDS YP_193548.1 58336963 3252896 complement(623869..626055) 1 NC_006814.3 ClpE; ATP-dependent Clp protease, ATP-binding subunit 626055 clpE 3252896 clpE Lactobacillus acidophilus NCFM ATP-dependent Clp protease, ATP-binding subunit YP_193548.1 623869 R 272621 CDS YP_193549.1 58336964 3252285 626544..626810 1 NC_006814.3 PthP; COG1925 Phosphotransferase system, HPr-related protein; phosphocarrier protein HPr 626810 ptsH 3252285 ptsH Lactobacillus acidophilus NCFM phosphocarrier protein HPr YP_193549.1 626544 D 272621 CDS YP_193550.1 58336965 3252693 626810..628543 1 NC_006814.3 p-enolpyruvate-protein p-transferase PTSI 628543 ptsI 3252693 ptsI Lactobacillus acidophilus NCFM p-enolpyruvate-protein p-transferase PTSI YP_193550.1 626810 D 272621 CDS YP_193551.1 58336966 3252479 628754..629152 1 NC_006814.3 ArsC; arsenate reductase 629152 arsC 3252479 arsC Lactobacillus acidophilus NCFM arsenate reductase YP_193551.1 628754 D 272621 CDS YP_193552.1 58336967 3252391 629297..630037 1 NC_006814.3 enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence; adaptor protein 630037 mecA 3252391 mecA Lactobacillus acidophilus NCFM adaptor protein YP_193552.1 629297 D 272621 CDS YP_193553.1 58336968 3253027 630121..630984 1 NC_006814.3 CoiA; COG4469 Competence protein; competence protein 630984 coiA 3253027 coiA Lactobacillus acidophilus NCFM competence protein YP_193553.1 630121 D 272621 CDS YP_193554.1 58336969 3252241 complement(630981..631601) 1 NC_006814.3 hypothetical protein 631601 3252241 LBA0644 Lactobacillus acidophilus NCFM hypothetical protein YP_193554.1 630981 R 272621 CDS YP_193555.1 58336970 3252794 complement(631681..632295) 1 NC_006814.3 hypothetical protein 632295 3252794 LBA0645 Lactobacillus acidophilus NCFM hypothetical protein YP_193555.1 631681 R 272621 CDS YP_193556.1 58336971 3252716 632372..633004 1 NC_006814.3 GTP pyrophosphokinase 633004 3252716 LBA0646 Lactobacillus acidophilus NCFM GTP pyrophosphokinase YP_193556.1 632372 D 272621 CDS YP_193557.1 58336972 3252524 633001..633804 1 NC_006814.3 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 633804 ppnK 3252524 ppnK Lactobacillus acidophilus NCFM inorganic polyphosphate/ATP-NAD kinase YP_193557.1 633001 D 272621 CDS YP_193558.1 58336973 3252286 633797..634699 1 NC_006814.3 RluD; ribosomal large subunit pseudouridine synthase 634699 rluD 3252286 rluD Lactobacillus acidophilus NCFM ribosomal large subunit pseudouridine synthase YP_193558.1 633797 D 272621 CDS YP_193559.1 58336974 3252762 634806..636581 1 NC_006814.3 in group A Streptococci this protein was found to cross react with anti myosin antibodies and may play a role in rheumatic fever; hypothetical protein 636581 3252762 LBA0649 Lactobacillus acidophilus NCFM hypothetical protein YP_193559.1 634806 D 272621 CDS YP_193560.1 58336975 3252676 complement(636608..637300) 1 NC_006814.3 COG0398 Uncharacterized conserved protein; hypothetical protein 637300 3252676 LBA0650 Lactobacillus acidophilus NCFM hypothetical protein YP_193560.1 636608 R 272621 CDS YP_193561.1 58336976 3252121 complement(637393..638421) 1 NC_006814.3 COG2706 3-carboxymuconate cyclase; isomerase 638421 3252121 LBA0651 Lactobacillus acidophilus NCFM isomerase YP_193561.1 637393 R 272621 CDS YP_193562.1 58336977 3252423 638578..641337 1 NC_006814.3 PacL; COG0474 Cation transport ATPase; H+-K+-exchanging ATPase 641337 pacL 3252423 pacL Lactobacillus acidophilus NCFM H+-K+-exchanging ATPase YP_193562.1 638578 D 272621 CDS YP_193563.1 58336978 3253055 641407..641787 1 NC_006814.3 PthA; phosphotransferase system enzyme II 641787 pthA 3253055 pthA Lactobacillus acidophilus NCFM phosphotransferase system enzyme II YP_193563.1 641407 D 272621 CDS YP_193564.1 58336979 3252757 641803..642990 1 NC_006814.3 COG0628 Predicted permease; permease 642990 3252757 LBA0656 Lactobacillus acidophilus NCFM permease YP_193564.1 641803 D 272621 CDS YP_193565.1 58336980 3252163 643053..643607 1 NC_006814.3 rRNA methylase 643607 3252163 LBA0657 Lactobacillus acidophilus NCFM rRNA methylase YP_193565.1 643053 D 272621 CDS YP_193566.1 58336981 3252887 643609..643998 1 NC_006814.3 hypothetical protein 643998 3252887 LBA0658 Lactobacillus acidophilus NCFM hypothetical protein YP_193566.1 643609 D 272621 CDS YP_193567.1 58336982 3252018 644021..646456 1 NC_006814.3 SpoIIIe; DNA translocase FtsK 646456 3252018 LBA0659 Lactobacillus acidophilus NCFM DNA translocase FtsK YP_193567.1 644021 D 272621 CDS YP_193568.1 58336983 3252871 646443..647657 1 NC_006814.3 COG0612 Predicted Zn-dependent peptidases; protease 647657 3252871 LBA0660 Lactobacillus acidophilus NCFM protease YP_193568.1 646443 D 272621 CDS YP_193569.1 58336984 3251188 647654..648907 1 NC_006814.3 COG0612 Predicted Zn-dependent peptidases; protease 648907 3251188 LBA0661 Lactobacillus acidophilus NCFM protease YP_193569.1 647654 D 272621 CDS YP_193570.1 58336985 3251189 648912..649640 1 NC_006814.3 FabG; 3-oxoacyl-ACP reductase 649640 fabG 3251189 fabG Lactobacillus acidophilus NCFM 3-oxoacyl-ACP reductase YP_193570.1 648912 D 272621 CDS YP_193571.1 58336986 3251190 649708..650832 1 NC_006814.3 transcriptional regulator 650832 3251190 LBA0663 Lactobacillus acidophilus NCFM transcriptional regulator YP_193571.1 649708 D 272621 CDS YP_193572.1 58336987 3251191 650855..651415 1 NC_006814.3 PgsA; CDP-diacylglycerol- phosphatephosphatidyltransferase 651415 pgsA 3251191 pgsA Lactobacillus acidophilus NCFM CDP-diacylglycerol- phosphatephosphatidyltransferase YP_193572.1 650855 D 272621 CDS YP_193573.1 58336988 3251200 651592..652683 1 NC_006814.3 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 652683 recA 3251200 recA Lactobacillus acidophilus NCFM recombinase A YP_193573.1 651592 D 272621 CDS YP_193574.1 58336989 3251199 652801..654432 1 NC_006814.3 protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP; phosphodiesterase 654432 ymdA 3251199 ymdA Lactobacillus acidophilus NCFM phosphodiesterase YP_193574.1 652801 D 272621 CDS YP_193575.1 58336990 3251207 654533..655702 1 NC_006814.3 RgpG; undecaprenyl-phosphaten-acetyl- glucosaminyltransfera se 655702 3251207 LBA0668 Lactobacillus acidophilus NCFM undecaprenyl-phosphaten-acetyl- glucosaminyltransfera se YP_193575.1 654533 D 272621 CDS YP_193576.1 58336991 3251482 complement(655728..656390) 1 NC_006814.3 YvyE; hypothetical protein 656390 3251482 LBA0669 Lactobacillus acidophilus NCFM hypothetical protein YP_193576.1 655728 R 272621 CDS YP_193577.1 58336992 3251222 656433..657716 1 NC_006814.3 ComFA; ComF1; competence protein 657716 3251222 LBA0670 Lactobacillus acidophilus NCFM competence protein YP_193577.1 656433 D 272621 CDS YP_193578.1 58336993 3251221 657713..658408 1 NC_006814.3 ComFC; COG1040 Predicted amidophosphoribosyltransferases; competence protein 658408 3251221 LBA0671 Lactobacillus acidophilus NCFM competence protein YP_193578.1 657713 D 272621 CDS YP_193579.1 58336994 3251220 658491..659033 1 NC_006814.3 YvyD; phosphate starvation inducible protein stressrelated 659033 yvyD 3251220 yvyD Lactobacillus acidophilus NCFM phosphate starvation inducible protein stressrelated YP_193579.1 658491 D 272621 CDS YP_193580.1 58336995 3251228 659172..661571 1 NC_006814.3 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, there are paralogous proteins that have been found to be nonessential but do function in secretion of a subset of exported proteins; preprotein translocase subunit SecA 661571 secA 3251228 secA Lactobacillus acidophilus NCFM preprotein translocase subunit SecA YP_193580.1 659172 D 272621 CDS YP_193581.1 58336996 3251240 661748..662746 1 NC_006814.3 RF2; peptide chain release factor 2 662746 3251240 LBA0674 Lactobacillus acidophilus NCFM peptide chain release factor 2 YP_193581.1 661748 D 272621 CDS YP_193582.1 58336997 3251239 662754..663029 1 NC_006814.3 MP1; hypothetical protein 663029 3251239 LBA0675 Lactobacillus acidophilus NCFM hypothetical protein YP_193582.1 662754 D 272621 CDS YP_193583.1 58336998 3251241 663045..664013 1 NC_006814.3 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase 664013 ptsK 3251241 ptsK Lactobacillus acidophilus NCFM HPr kinase/phosphorylase YP_193583.1 663045 D 272621 CDS YP_193584.1 58336999 3251248 664003..664845 1 NC_006814.3 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 664845 3251248 LBA0677 Lactobacillus acidophilus NCFM prolipoprotein diacylglyceryl transferase YP_193584.1 664003 D 272621 CDS YP_193585.1 58337000 3251486 664885..665904 1 NC_006814.3 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 665904 gpsA 3251486 gpsA Lactobacillus acidophilus NCFM NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_193585.1 664885 D 272621 CDS YP_193586.1 58337001 3251218 665981..666907 1 NC_006814.3 TrxB; COG0492 Thioredoxin reductase; thioredoxin reductase 666907 trxB 3251218 trxB Lactobacillus acidophilus NCFM thioredoxin reductase YP_193586.1 665981 D 272621 CDS YP_193587.1 58337002 3251253 667085..669001 1 NC_006814.3 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein 669001 glgB 3251253 glgB Lactobacillus acidophilus NCFM glycogen branching protein YP_193587.1 667085 D 272621 CDS YP_193588.1 58337003 3251252 669017..670162 1 NC_006814.3 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 670162 glgC 3251252 glgC Lactobacillus acidophilus NCFM glucose-1-phosphate adenylyltransferase YP_193588.1 669017 D 272621 CDS YP_193589.1 58337004 3251257 670152..671294 1 NC_006814.3 GlgD; Required for glycogen biosynthesis; glucose-1-phosphate adenylyltransferase 671294 glgD 3251257 glgD Lactobacillus acidophilus NCFM glucose-1-phosphate adenylyltransferase YP_193589.1 670152 D 272621 CDS YP_193590.1 58337005 3251261 671304..672734 1 NC_006814.3 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 672734 glgA 3251261 glgA Lactobacillus acidophilus NCFM glycogen synthase YP_193590.1 671304 D 272621 CDS YP_193591.1 58337006 3251260 672753..675164 1 NC_006814.3 glycogen phosphorylase 675164 3251260 LBA0685 Lactobacillus acidophilus NCFM glycogen phosphorylase YP_193591.1 672753 D 272621 CDS YP_193592.1 58337007 3251263 675164..676933 1 NC_006814.3 amylopullulanase 676933 3251263 LBA0686 Lactobacillus acidophilus NCFM amylopullulanase YP_193592.1 675164 D 272621 CDS YP_193593.1 58337008 3251266 677052..678776 1 NC_006814.3 COG1109 Phosphomannomutase; phosphoglucomutase 678776 3251266 LBA0687 Lactobacillus acidophilus NCFM phosphoglucomutase YP_193593.1 677052 D 272621 CDS YP_193594.1 58337009 3251267 678879..680930 1 NC_006814.3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 680930 uvrB 3251267 uvrB Lactobacillus acidophilus NCFM excinuclease ABC subunit B YP_193594.1 678879 D 272621 CDS YP_193595.1 58337010 3251349 680917..683757 1 NC_006814.3 UvrA; excinuclease subunit A 683757 uvrA 3251349 uvrA Lactobacillus acidophilus NCFM excinuclease subunit A YP_193595.1 680917 D 272621 CDS YP_193596.1 58337011 3251270 683820..684362 1 NC_006814.3 COG3247 Uncharacterized conserved protein; hypothetical protein 684362 3251270 LBA0690 Lactobacillus acidophilus NCFM hypothetical protein YP_193596.1 683820 D 272621 CDS YP_193597.1 58337012 3251276 684444..685325 1 NC_006814.3 COG1660 Predicted P-loop-containing kinase; hypothetical protein 685325 3251276 LBA0691 Lactobacillus acidophilus NCFM hypothetical protein YP_193597.1 684444 D 272621 CDS YP_193598.1 58337013 3251278 685335..686378 1 NC_006814.3 COG0391 Uncharacterized conserved protein; hypothetical protein 686378 3251278 LBA0692 Lactobacillus acidophilus NCFM hypothetical protein YP_193598.1 685335 D 272621 CDS YP_193599.1 58337014 3251283 686371..687306 1 NC_006814.3 hypothetical protein 687306 3251283 LBA0693 Lactobacillus acidophilus NCFM hypothetical protein YP_193599.1 686371 D 272621 CDS YP_193600.1 58337015 3251282 complement(687346..687933) 1 NC_006814.3 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 687933 clpP 3251282 clpP Lactobacillus acidophilus NCFM ATP-dependent Clp protease proteolytic subunit YP_193600.1 687346 R 272621 CDS YP_193601.1 58337016 3251287 688100..689752 1 NC_006814.3 hypothetical protein 689752 3251287 LBA0695 Lactobacillus acidophilus NCFM hypothetical protein YP_193601.1 688100 D 272621 CDS YP_193602.1 58337017 3251288 complement(689813..691249) 1 NC_006814.3 amino acid transport protein; amino acid permease 691249 3251288 LBA0696 Lactobacillus acidophilus NCFM amino acid permease YP_193602.1 689813 R 272621 CDS YP_193603.1 58337018 3251296 691863..692894 1 NC_006814.3 transcriptional regulator 692894 3251296 LBA0697 Lactobacillus acidophilus NCFM transcriptional regulator YP_193603.1 691863 D 272621 CDS YP_193604.1 58337019 3251298 692948..693964 1 NC_006814.3 COG0057 Glyceraldehyde-3-phosphate dehydrogenase-erythrose-4-phosphate dehydrogenase; glyceraldehyde-3-p dehydrogenase 693964 3251298 LBA0698 Lactobacillus acidophilus NCFM glyceraldehyde-3-p dehydrogenase YP_193604.1 692948 D 272621 CDS YP_193605.1 58337020 3251301 694078..695289 1 NC_006814.3 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 695289 pgk 3251301 pgk Lactobacillus acidophilus NCFM phosphoglycerate kinase YP_193605.1 694078 D 272621 CDS YP_193606.1 58337021 3251300 695315..696073 1 NC_006814.3 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 696073 tpiA 3251300 tpiA Lactobacillus acidophilus NCFM triosephosphate isomerase YP_193606.1 695315 D 272621 CDS YP_193607.1 58337022 3251308 complement(696391..696912) 1 NC_006814.3 hypothetical protein 696912 3251308 LBA0701 Lactobacillus acidophilus NCFM hypothetical protein YP_193607.1 696391 R 272621 CDS YP_193608.1 58337023 3251309 complement(696925..697800) 1 NC_006814.3 HAD family phosphatase 697800 3251309 LBA0702 Lactobacillus acidophilus NCFM HAD family phosphatase YP_193608.1 696925 R 272621 CDS YP_193609.1 58337024 3251315 697868..698566 1 NC_006814.3 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 698566 3251315 LBA0703 Lactobacillus acidophilus NCFM uracil-DNA glycosylase YP_193609.1 697868 D 272621 CDS YP_193610.1 58337025 3251318 698578..699567 1 NC_006814.3 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase 699567 eutD 3251318 eutD Lactobacillus acidophilus NCFM phosphotransacetylase YP_193610.1 698578 D 272621 CDS YP_193611.1 58337026 3251319 699567..700046 1 NC_006814.3 hypothetical protein 700046 3251319 LBA0705 Lactobacillus acidophilus NCFM hypothetical protein YP_193611.1 699567 D 272621 CDS YP_193612.1 58337027 3251321 complement(700121..700654) 1 NC_006814.3 DNA polymerase III subunit alpha 700654 3251321 LBA0706 Lactobacillus acidophilus NCFM DNA polymerase III subunit alpha YP_193612.1 700121 R 272621 CDS YP_193613.1 58337028 3251327 700750..701646 1 NC_006814.3 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 701646 murB 3251327 murB Lactobacillus acidophilus NCFM UDP-N-acetylenolpyruvoylglucosamine reductase YP_193613.1 700750 D 272621 CDS YP_193614.1 58337029 3251329 701705..702802 1 NC_006814.3 PotA; spermidine and putrescine ABC transporter ATP-binding protein 702802 potA 3251329 potA Lactobacillus acidophilus NCFM spermidine and putrescine ABC transporter ATP-binding protein YP_193614.1 701705 D 272621 CDS YP_193615.1 58337030 3251333 702792..703604 1 NC_006814.3 PotB; spermidine-putrescine ABC transporter permease 703604 potB 3251333 potB Lactobacillus acidophilus NCFM spermidine-putrescine ABC transporter permease YP_193615.1 702792 D 272621 CDS YP_193616.1 58337031 3251332 703601..704416 1 NC_006814.3 PotC; spermidine and putrescine ABC transporter permease 704416 potC 3251332 potC Lactobacillus acidophilus NCFM spermidine and putrescine ABC transporter permease YP_193616.1 703601 D 272621 CDS YP_193617.1 58337032 3251334 704413..705486 1 NC_006814.3 PotD; spermidine and putrescine periplasmatic ABC transporter 705486 potD 3251334 potD Lactobacillus acidophilus NCFM spermidine and putrescine periplasmatic ABC transporter YP_193617.1 704413 D 272621 CDS YP_193618.1 58337033 3251346 705523..706365 1 NC_006814.3 COG1624 Uncharacterized conserved protein; hypothetical protein 706365 3251346 LBA0714 Lactobacillus acidophilus NCFM hypothetical protein YP_193618.1 705523 D 272621 CDS YP_193619.1 58337034 3251345 706362..707321 1 NC_006814.3 hypothetical protein 707321 3251345 LBA0715 Lactobacillus acidophilus NCFM hypothetical protein YP_193619.1 706362 D 272621 CDS YP_193620.1 58337035 3251353 707353..708711 1 NC_006814.3 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 708711 glmM 3251353 glmM Lactobacillus acidophilus NCFM phosphoglucosamine mutase YP_193620.1 707353 D 272621 CDS YP_193621.1 58337036 3251352 708811..709626 1 NC_006814.3 HAD superfamily hydrolase 709626 3251352 LBA0717 Lactobacillus acidophilus NCFM HAD superfamily hydrolase YP_193621.1 708811 D 272621 CDS YP_193622.1 58337037 3251357 709660..710445 1 NC_006814.3 HAD superfamily hydrolase 710445 3251357 LBA0718 Lactobacillus acidophilus NCFM HAD superfamily hydrolase YP_193622.1 709660 D 272621 CDS YP_193623.1 58337038 3251358 710539..711255 1 NC_006814.3 hypothetical protein 711255 3251358 LBA0720 Lactobacillus acidophilus NCFM hypothetical protein YP_193623.1 710539 D 272621 CDS YP_193624.1 58337039 3251359 711259..711717 1 NC_006814.3 phosphotyrosinase phosphatase; protein-tyrosine-phosphatase 711717 3251359 LBA0722 Lactobacillus acidophilus NCFM protein-tyrosine-phosphatase YP_193624.1 711259 D 272621 CDS YP_193625.1 58337040 3251362 complement(711741..712877) 1 NC_006814.3 glycerate kinase 712877 3251362 LBA0723 Lactobacillus acidophilus NCFM glycerate kinase YP_193625.1 711741 R 272621 CDS YP_193626.1 58337041 3251365 713104..713949 1 NC_006814.3 LicT; COG3711 transcriptional antiterminator; transcription antiterminator 713949 licT 3251365 licT Lactobacillus acidophilus NCFM transcription antiterminator YP_193626.1 713104 D 272621 CDS YP_193627.1 58337042 3251364 714074..716065 1 NC_006814.3 COG1263 Phosphotransferase system IIC components, glucose-maltose-N-acetylglucosamine-specific; phosphotransferase system enzyme II 716065 3251364 LBA0725 Lactobacillus acidophilus NCFM phosphotransferase system enzyme II YP_193627.1 714074 D 272621 CDS YP_193628.1 58337043 3251383 716147..717622 1 NC_006814.3 COG2723 Beta-glucosidase-6-phospho-beta-glucosidase -beta-galactosidase; phospho-beta-galactosidase II 717622 3251383 LBA0726 Lactobacillus acidophilus NCFM phospho-beta-galactosidase II YP_193628.1 716147 D 272621 CDS YP_193629.1 58337044 3251386 717751..718698 1 NC_006814.3 hypothetical protein 718698 3251386 LBA0728 Lactobacillus acidophilus NCFM hypothetical protein YP_193629.1 717751 D 272621 CDS YP_193630.1 58337045 3251385 complement(718753..720378) 1 NC_006814.3 COG0531 Amino acid transporters; amino acid permease 720378 3251385 LBA0729 Lactobacillus acidophilus NCFM amino acid permease YP_193630.1 718753 R 272621 CDS YP_193631.1 58337046 3251392 720642..720743 1 NC_006814.3 hypothetical protein 720743 3251392 LBA0730 Lactobacillus acidophilus NCFM hypothetical protein YP_193631.1 720642 D 272621 CDS YP_003864082.1 304650758 9714950 720753..720938 1 NC_006814.3 30S ribosomal protein S14 720938 9714950 LBA0730a Lactobacillus acidophilus NCFM 30S ribosomal protein S14 YP_003864082.1 720753 D 272621 CDS YP_193632.1 58337047 3251350 721103..721618 1 NC_006814.3 hypothetical protein 721618 3251350 LBA0732 Lactobacillus acidophilus NCFM hypothetical protein YP_193632.1 721103 D 272621 CDS YP_193633.1 58337048 3251398 721708..722436 1 NC_006814.3 COG0217 Uncharacterized conserved protein; hypothetical protein 722436 3251398 LBA0733 Lactobacillus acidophilus NCFM hypothetical protein YP_193633.1 721708 D 272621 CDS YP_193634.1 58337049 3251407 722562..723536 1 NC_006814.3 CglA; competence protein 723536 cglA 3251407 cglA Lactobacillus acidophilus NCFM competence protein YP_193634.1 722562 D 272621 CDS YP_193635.1 58337050 3251406 723502..724506 1 NC_006814.3 ComGB; competence protein 724506 3251406 LBA0735 Lactobacillus acidophilus NCFM competence protein YP_193635.1 723502 D 272621 CDS YP_193636.1 58337051 3251405 724519..724878 1 NC_006814.3 ComGC; COG4537 Competence protein ComGC; competence protein 724878 3251405 LBA0737 Lactobacillus acidophilus NCFM competence protein YP_193636.1 724519 D 272621 CDS YP_193637.1 58337052 3251432 724844..725272 1 NC_006814.3 hypothetical protein 725272 3251432 LBA0738 Lactobacillus acidophilus NCFM hypothetical protein YP_193637.1 724844 D 272621 CDS YP_193638.1 58337053 3251431 725459..726061 1 NC_006814.3 hypothetical protein 726061 3251431 LBA0739 Lactobacillus acidophilus NCFM hypothetical protein YP_193638.1 725459 D 272621 CDS YP_193639.1 58337054 3251430 726235..727236 1 NC_006814.3 COG0827 Adenine-specific DNA methylase; modification methylase 727236 3251430 LBA0740 Lactobacillus acidophilus NCFM modification methylase YP_193639.1 726235 D 272621 CDS YP_193640.1 58337055 3251371 727277..728461 1 NC_006814.3 AckB; acetate kinase 728461 ackB 3251371 ackB Lactobacillus acidophilus NCFM acetate kinase YP_193640.1 727277 D 272621 CDS YP_193641.1 58337056 3251370 729095..729985 1 NC_006814.3 hypothetical protein 729985 3251370 LBA0742 Lactobacillus acidophilus NCFM hypothetical protein YP_193641.1 729095 D 272621 CDS YP_193642.1 58337057 3251437 730074..730979 1 NC_006814.3 potential frameshift to 744; PLP-dependent aminotransferase 730979 3251437 LBA0743 Lactobacillus acidophilus NCFM PLP-dependent aminotransferase YP_193642.1 730074 D 272621 CDS YP_193643.1 58337058 3251438 730952..731155 1 NC_006814.3 potential frameshift to 743; PLP-dependent aminotransferase 731155 3251438 LBA0744 Lactobacillus acidophilus NCFM PLP-dependent aminotransferase YP_193643.1 730952 D 272621 CDS YP_193644.1 58337059 3251439 731224..732189 1 NC_006814.3 COG1482 Phosphomannose isomerase; mannose-6-phosphate isomerase 732189 3251439 LBA0745 Lactobacillus acidophilus NCFM mannose-6-phosphate isomerase YP_193644.1 731224 D 272621 CDS YP_193645.1 58337060 3251441 732616..733338 1 NC_006814.3 COG0745 Response regulators conserved isting of a CheY-like receiver domain and a winged-helix DNA-binding domain; response regulator 733338 3251441 LBA0746 Lactobacillus acidophilus NCFM response regulator YP_193645.1 732616 D 272621 CDS YP_193646.1 58337061 3251444 733341..734792 1 NC_006814.3 histidine kinase 734792 3251444 LBA0747 Lactobacillus acidophilus NCFM histidine kinase YP_193646.1 733341 D 272621 CDS YP_193647.1 58337062 3251447 734917..735291 1 NC_006814.3 potential frameshift to 749; oxidoreductase 735291 3251447 LBA0748 Lactobacillus acidophilus NCFM oxidoreductase YP_193647.1 734917 D 272621 CDS YP_193648.1 58337063 3251446 735327..735980 1 NC_006814.3 potential frameshift to 748; oxidoreductase 735980 3251446 LBA0749 Lactobacillus acidophilus NCFM oxidoreductase YP_193648.1 735327 D 272621 CDS YP_193649.1 58337064 3251560 complement(736014..738191) 1 NC_006814.3 alkaline phosphatase 738191 3251560 LBA0750 Lactobacillus acidophilus NCFM alkaline phosphatase YP_193649.1 736014 R 272621 CDS YP_193650.1 58337065 3251453 738333..738935 1 NC_006814.3 VanZ; hypothetical protein 738935 vanZ 3251453 vanZ Lactobacillus acidophilus NCFM hypothetical protein YP_193650.1 738333 D 272621 CDS YP_193651.1 58337066 3252080 739022..740359 1 NC_006814.3 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 740359 pgi 3252080 pgi Lactobacillus acidophilus NCFM glucose-6-phosphate isomerase YP_193651.1 739022 D 272621 CDS YP_193652.1 58337067 3252072 740473..741861 1 NC_006814.3 multi-drug-type permease 741861 3252072 LBA0753 Lactobacillus acidophilus NCFM multi-drug-type permease YP_193652.1 740473 D 272621 CDS YP_193653.1 58337068 3251465 complement(741942..742955) 1 NC_006814.3 b-lactamase; esterase 742955 3251465 LBA0754 Lactobacillus acidophilus NCFM esterase YP_193653.1 741942 R 272621 CDS YP_193654.1 58337069 3251494 743529..743900 1 NC_006814.3 COG3459 Cellobiose phosphorylase; hypothetical protein 743900 3251494 LBA0755 Lactobacillus acidophilus NCFM hypothetical protein YP_193654.1 743529 D 272621 CDS YP_193655.1 58337070 3251254 complement(745463..746965) 1 NC_006814.3 DNA primase 746965 3251254 LBA0757 Lactobacillus acidophilus NCFM DNA primase YP_193655.1 745463 R 272621 CDS YP_193656.1 58337071 3251480 complement(747077..747301) 1 NC_006814.3 conserved domain protein; prophage DNA packaging protein NU1 747301 3251480 LBA0758 Lactobacillus acidophilus NCFM prophage DNA packaging protein NU1 YP_193656.1 747077 R 272621 CDS YP_193657.1 58337072 3251478 complement(747374..747598) 1 NC_006814.3 hypothetical protein 747598 3251478 LBA0759 Lactobacillus acidophilus NCFM hypothetical protein YP_193657.1 747374 R 272621 CDS YP_193658.1 58337073 3251500 complement(747602..747985) 1 NC_006814.3 CGI-01 protein; hypothetical protein 747985 3251500 LBA0760 Lactobacillus acidophilus NCFM hypothetical protein YP_193658.1 747602 R 272621 CDS YP_193659.1 58337074 3251502 complement(747989..748207) 1 NC_006814.3 hypothetical protein 748207 3251502 LBA0761 Lactobacillus acidophilus NCFM hypothetical protein YP_193659.1 747989 R 272621 CDS YP_193660.1 58337075 3253045 complement(748200..748406) 1 NC_006814.3 prophage Lp3 protein 4; hypothetical protein 748406 3253045 LBA0762 Lactobacillus acidophilus NCFM hypothetical protein YP_193660.1 748200 R 272621 CDS YP_193661.1 58337076 3251412 748541..749092 1 NC_006814.3 similar to Orf32 Bacteriophage bIL309; hypothetical protein 749092 3251412 LBA0763 Lactobacillus acidophilus NCFM hypothetical protein YP_193661.1 748541 D 272621 CDS YP_193662.1 58337077 3251464 749258..750328 1 NC_006814.3 integrase 750328 3251464 LBA0764 Lactobacillus acidophilus NCFM integrase YP_193662.1 749258 D 272621 CDS YP_193663.1 58337078 3251507 complement(750576..751928) 1 NC_006814.3 COG0769 UDP-N-acetylmuramyl tripeptide synthase; UDP-N-acetylmuramyl tripeptide synthetase 751928 3251507 LBA0765 Lactobacillus acidophilus NCFM UDP-N-acetylmuramyl tripeptide synthetase YP_193663.1 750576 R 272621 CDS YP_193664.1 58337079 3251539 752052..752675 1 NC_006814.3 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 752675 3251539 LBA0766 Lactobacillus acidophilus NCFM thymidine kinase YP_193664.1 752052 D 272621 CDS YP_193665.1 58337080 3251514 752691..753776 1 NC_006814.3 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 753776 prfA 3251514 prfA Lactobacillus acidophilus NCFM peptide chain release factor 1 YP_193665.1 752691 D 272621 CDS YP_193666.1 58337081 3251513 753769..754611 1 NC_006814.3 HemK; protoporphyrinogen oxidase 754611 hemK 3251513 hemK Lactobacillus acidophilus NCFM protoporphyrinogen oxidase YP_193666.1 753769 D 272621 CDS YP_193667.1 58337082 3251512 754608..755612 1 NC_006814.3 Sua5 family translation factor 755612 3251512 LBA0769 Lactobacillus acidophilus NCFM Sua5 family translation factor YP_193667.1 754608 D 272621 CDS YP_193668.1 58337083 3251533 755699..756328 1 NC_006814.3 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 756328 upp 3251533 upp Lactobacillus acidophilus NCFM uracil phosphoribosyltransferase YP_193668.1 755699 D 272621 CDS YP_193669.1 58337084 3251532 756451..757164 1 NC_006814.3 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A 757164 3251532 LBA0772 Lactobacillus acidophilus NCFM ATP synthase F0F1 subunit A YP_193669.1 756451 D 272621 CDS YP_193670.1 58337085 3251546 757185..757418 1 NC_006814.3 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C 757418 3251546 LBA0773 Lactobacillus acidophilus NCFM ATP synthase F0F1 subunit C YP_193670.1 757185 D 272621 CDS YP_193671.1 58337086 3251547 757475..757984 1 NC_006814.3 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B 757984 3251547 LBA0774 Lactobacillus acidophilus NCFM ATP synthase F0F1 subunit B YP_193671.1 757475 D 272621 CDS YP_193672.1 58337087 3251545 757984..758532 1 NC_006814.3 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta 758532 3251545 LBA0775 Lactobacillus acidophilus NCFM ATP synthase F0F1 subunit delta YP_193672.1 757984 D 272621 CDS YP_193673.1 58337088 3251553 758547..760058 1 NC_006814.3 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha 760058 3251553 LBA0776 Lactobacillus acidophilus NCFM ATP synthase F0F1 subunit alpha YP_193673.1 758547 D 272621 CDS YP_193674.1 58337089 3251556 760069..761031 1 NC_006814.3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma 761031 3251556 LBA0777 Lactobacillus acidophilus NCFM ATP synthase F0F1 subunit gamma YP_193674.1 760069 D 272621 CDS YP_193675.1 58337090 3251562 761054..762493 1 NC_006814.3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta 762493 3251562 LBA0778 Lactobacillus acidophilus NCFM ATP synthase F0F1 subunit beta YP_193675.1 761054 D 272621 CDS YP_193676.1 58337091 3251564 762505..762945 1 NC_006814.3 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon 762945 atpC 3251564 atpC Lactobacillus acidophilus NCFM ATP synthase F0F1 subunit epsilon YP_193676.1 762505 D 272621 CDS YP_193677.1 58337092 3251566 763329..764318 1 NC_006814.3 MreB; rod shape-determining protein MreB 764318 mreB 3251566 mreB Lactobacillus acidophilus NCFM rod shape-determining protein MreB YP_193677.1 763329 D 272621 CDS YP_193678.1 58337093 3251569 764634..764861 1 NC_006814.3 hypothetical protein 764861 3251569 LBA0781 Lactobacillus acidophilus NCFM hypothetical protein YP_193678.1 764634 D 272621 CDS YP_193679.1 58337094 3251568 764883..766076 1 NC_006814.3 RodA; rod shape-determining protein 766076 rodA 3251568 rodA Lactobacillus acidophilus NCFM rod shape-determining protein YP_193679.1 764883 D 272621 CDS YP_193680.1 58337095 3251580 complement(766143..766607) 1 NC_006814.3 hypothetical protein 766607 3251580 LBA0783 Lactobacillus acidophilus NCFM hypothetical protein YP_193680.1 766143 R 272621 CDS YP_193681.1 58337096 3251581 complement(767249..768568) 1 NC_006814.3 recombination factor protein RarA 768568 3251581 LBA0784 Lactobacillus acidophilus NCFM recombination factor protein RarA YP_193681.1 767249 R 272621 CDS YP_193682.1 58337097 3251579 complement(768571..769038) 1 NC_006814.3 hypothetical protein 769038 3251579 LBA0785 Lactobacillus acidophilus NCFM hypothetical protein YP_193682.1 768571 R 272621 CDS YP_193683.1 58337098 3251582 complement(769129..769740) 1 NC_006814.3 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 769740 rpsD 3251582 rpsD Lactobacillus acidophilus NCFM 30S ribosomal protein S4 YP_193683.1 769129 R 272621 CDS YP_193684.1 58337099 3251586 770022..771734 1 NC_006814.3 acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation; septation ring formation regulator EzrA 771734 3251586 LBA0788 Lactobacillus acidophilus NCFM septation ring formation regulator EzrA YP_193684.1 770022 D 272621 CDS YP_193685.1 58337100 3251589 771822..772982 1 NC_006814.3 family; NifS; aminotransferase 772982 nifS 3251589 nifS Lactobacillus acidophilus NCFM aminotransferase YP_193685.1 771822 D 272621 CDS YP_193686.1 58337101 3251588 772982..774199 1 NC_006814.3 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 774199 thiI 3251588 thiI Lactobacillus acidophilus NCFM thiamine biosynthesis protein ThiI YP_193686.1 772982 D 272621 CDS YP_193687.1 58337102 3251591 774246..774956 1 NC_006814.3 16s pseudouridylate synthase 774956 3251591 LBA0791 Lactobacillus acidophilus NCFM 16s pseudouridylate synthase YP_193687.1 774246 D 272621 CDS YP_193688.1 58337103 3251596 775118..775270 1 NC_006814.3 hypothetical protein 775270 3251596 LBA0792 Lactobacillus acidophilus NCFM hypothetical protein YP_193688.1 775118 D 272621 CDS YP_193689.1 58337104 3251595 775697..775819 1 NC_006814.3 hypothetical protein 775819 3251595 LBA0793 Lactobacillus acidophilus NCFM hypothetical protein YP_193689.1 775697 D 272621 CDS YP_193690.1 58337105 3251600 776256..778895 1 NC_006814.3 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 778895 valS 3251600 valS Lactobacillus acidophilus NCFM valyl-tRNA synthetase YP_193690.1 776256 D 272621 CDS YP_193691.1 58337106 3251599 778896..780167 1 NC_006814.3 FolC; COG0285 Folylpolyglutamate synthase; folylpolyglutamate synthase 780167 folC 3251599 folC Lactobacillus acidophilus NCFM folylpolyglutamate synthase YP_193691.1 778896 D 272621 CDS YP_193692.1 58337107 3251603 780157..780834 1 NC_006814.3 COG0637 Predicted phosphatase-phosphohexomutase; hydrolase 780834 3251603 LBA0796 Lactobacillus acidophilus NCFM hydrolase YP_193692.1 780157 D 272621 CDS YP_193693.1 58337108 3251609 780871..781494 1 NC_006814.3 RadC; DNA repair protein RadC; DNA repair protein 781494 radC 3251609 radC Lactobacillus acidophilus NCFM DNA repair protein YP_193693.1 780871 D 272621 CDS YP_193694.1 58337109 3251611 781590..782594 1 NC_006814.3 functions in MreBCD complex in some organisms; rod shape-determining protein MreB 782594 mreB 3251611 mreB Lactobacillus acidophilus NCFM rod shape-determining protein MreB YP_193694.1 781590 D 272621 CDS YP_193695.1 58337110 3251614 782640..783491 1 NC_006814.3 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 783491 mreC 3251614 mreC Lactobacillus acidophilus NCFM rod shape-determining protein MreC YP_193695.1 782640 D 272621 CDS YP_193696.1 58337111 3251613 783491..784030 1 NC_006814.3 MreD; COG2891 Cell shape-determining protein; cell shape determining protein 784030 mreD 3251613 mreD Lactobacillus acidophilus NCFM cell shape determining protein YP_193696.1 783491 D 272621 CDS YP_193697.1 58337112 3251616 784295..784624 1 NC_006814.3 hypothetical protein 784624 3251616 LBA0802 Lactobacillus acidophilus NCFM hypothetical protein YP_193697.1 784295 D 272621 CDS YP_193698.1 58337113 3251619 785233..786180 1 NC_006814.3 MraW; S-adenosyl-methyltransferase MraW 786180 mraW 3251619 mraW Lactobacillus acidophilus NCFM S-adenosyl-methyltransferase MraW YP_193698.1 785233 D 272621 CDS YP_193699.1 58337114 3251621 786194..786556 1 NC_006814.3 FtsL; cell division protein 786556 ftsL 3251621 ftsL Lactobacillus acidophilus NCFM cell division protein YP_193699.1 786194 D 272621 CDS YP_193700.1 58337115 3251622 786556..788718 1 NC_006814.3 PBP2B; penicillin-binding protein 788718 3251622 LBA0805 Lactobacillus acidophilus NCFM penicillin-binding protein YP_193700.1 786556 D 272621 CDS YP_193701.1 58337116 3251626 788725..789693 1 NC_006814.3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 789693 mraY 3251626 mraY Lactobacillus acidophilus NCFM phospho-N-acetylmuramoyl-pentapeptide- transferase YP_193701.1 788725 D 272621 CDS YP_193702.1 58337117 3251625 789697..791076 1 NC_006814.3 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 791076 murD 3251625 murD Lactobacillus acidophilus NCFM UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_193702.1 789697 D 272621 CDS YP_193703.1 58337118 3251627 791079..792185 1 NC_006814.3 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 792185 murG 3251627 murG Lactobacillus acidophilus NCFM undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase YP_193703.1 791079 D 272621 CDS YP_193704.1 58337119 3251630 792203..793060 1 NC_006814.3 FtsQ; cell division protein 793060 ftsQ 3251630 ftsQ Lactobacillus acidophilus NCFM cell division protein YP_193704.1 792203 D 272621 CDS YP_193705.1 58337120 3251633 793121..794473 1 NC_006814.3 FtsA; cell division protein 794473 ftsA 3251633 ftsA Lactobacillus acidophilus NCFM cell division protein YP_193705.1 793121 D 272621 CDS YP_193706.1 58337121 3251637 794488..795846 1 NC_006814.3 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 795846 ftsZ 3251637 ftsZ Lactobacillus acidophilus NCFM cell division protein FtsZ YP_193706.1 794488 D 272621 CDS YP_193707.1 58337122 3251638 795865..796302 1 NC_006814.3 YlmF; cell division 796302 ylmF 3251638 ylmF Lactobacillus acidophilus NCFM cell division YP_193707.1 795865 D 272621 CDS YP_193708.1 58337123 3251642 796605..797405 1 NC_006814.3 YlmH; cell-division protein 797405 ylmH 3251642 ylmH Lactobacillus acidophilus NCFM cell-division protein YP_193708.1 796605 D 272621 CDS YP_193709.1 58337124 3251643 797381..798184 1 NC_006814.3 DivIVA; cell-division initiation protein 798184 3251643 LBA0816 Lactobacillus acidophilus NCFM cell-division initiation protein YP_193709.1 797381 D 272621 CDS YP_193710.1 58337125 3251646 798407..801190 1 NC_006814.3 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 801190 ileS 3251646 ileS Lactobacillus acidophilus NCFM isoleucyl-tRNA synthetase YP_193710.1 798407 D 272621 CDS YP_193711.1 58337126 3251648 801190..801393 1 NC_006814.3 COG1278 Cold shock protein; cold-shock protein 801393 3251648 LBA0818 Lactobacillus acidophilus NCFM cold-shock protein YP_193711.1 801190 D 272621 CDS YP_193712.1 58337127 3251650 801412..801981 1 NC_006814.3 MutT; ADP-ribose pyrophosphatase 801981 3251650 LBA0819 Lactobacillus acidophilus NCFM ADP-ribose pyrophosphatase YP_193712.1 801412 D 272621 CDS YP_193713.1 58337128 3251652 802317..803012 1 NC_006814.3 COG0775 Nucleoside phosphorylase; MTA-SAH nucleosidase 803012 3251652 LBA0820 Lactobacillus acidophilus NCFM MTA-SAH nucleosidase YP_193713.1 802317 D 272621 CDS YP_193714.1 58337129 3251655 803152..803493 1 NC_006814.3 hypothetical protein 803493 3251655 LBA0821 Lactobacillus acidophilus NCFM hypothetical protein YP_193714.1 803152 D 272621 CDS YP_193715.1 58337130 3251654 803501..804628 1 NC_006814.3 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 804628 mnmA 3251654 mnmA Lactobacillus acidophilus NCFM tRNA-specific 2-thiouridylase MnmA YP_193715.1 803501 D 272621 CDS YP_193716.1 58337131 3251658 804718..805377 1 NC_006814.3 COG0406 Fructose-2,6-bisphosphatase; phosphoglycerate mutase 805377 3251658 LBA0823 Lactobacillus acidophilus NCFM phosphoglycerate mutase YP_193716.1 804718 D 272621 CDS YP_193717.1 58337132 3251660 805377..806021 1 NC_006814.3 COG0457 FOG TPR repeat; hypothetical protein 806021 3251660 LBA0824 Lactobacillus acidophilus NCFM hypothetical protein YP_193717.1 805377 D 272621 CDS YP_193718.1 58337133 3251663 806021..808375 1 NC_006814.3 exodeoxyribonuclease V subunit alpha 808375 3251663 LBA0825 Lactobacillus acidophilus NCFM exodeoxyribonuclease V subunit alpha YP_193718.1 806021 D 272621 CDS YP_193719.1 58337134 3251666 808438..810117 1 NC_006814.3 hypothetical protein 810117 3251666 LBA0826 Lactobacillus acidophilus NCFM hypothetical protein YP_193719.1 808438 D 272621 CDS YP_193720.1 58337135 3251665 complement(810148..811095) 1 NC_006814.3 transcriptional regulator 811095 3251665 LBA0827 Lactobacillus acidophilus NCFM transcriptional regulator YP_193720.1 810148 R 272621 CDS YP_193721.1 58337136 3251671 complement(811148..812827) 1 NC_006814.3 metallo-b-lactamase superfamily protein 812827 3251671 LBA0828 Lactobacillus acidophilus NCFM metallo-b-lactamase superfamily protein YP_193721.1 811148 R 272621 CDS YP_193722.1 58337137 3251670 complement(812834..813055) 1 NC_006814.3 hypothetical protein 813055 3251670 LBA0829 Lactobacillus acidophilus NCFM hypothetical protein YP_193722.1 812834 R 272621 CDS YP_193723.1 58337138 3251675 complement(813398..813973) 1 NC_006814.3 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 813973 def 3251675 def Lactobacillus acidophilus NCFM peptide deformylase YP_193723.1 813398 R 272621 CDS YP_193724.1 58337139 3251677 814206..816050 1 NC_006814.3 TypA; BipAEFTU family GTPbinding protein 816050 bipA 3251677 bipA Lactobacillus acidophilus NCFM BipAEFTU family GTPbinding protein YP_193724.1 814206 D 272621 CDS YP_193725.1 58337140 3251680 816151..817335 1 NC_006814.3 FtsW; cell division protein 817335 ftsW 3251680 ftsW Lactobacillus acidophilus NCFM cell division protein YP_193725.1 816151 D 272621 CDS YP_193726.1 58337141 3251679 817332..817676 1 NC_006814.3 hypothetical protein 817676 3251679 LBA0834 Lactobacillus acidophilus NCFM hypothetical protein YP_193726.1 817332 D 272621 CDS YP_193727.1 58337142 3251685 817673..818224 1 NC_006814.3 COG0742 N6-adenine-specific methylase; hypothetical protein 818224 3251685 LBA0835 Lactobacillus acidophilus NCFM hypothetical protein YP_193727.1 817673 D 272621 CDS YP_193728.1 58337143 3251684 818224..818709 1 NC_006814.3 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 818709 coaD 3251684 coaD Lactobacillus acidophilus NCFM phosphopantetheine adenylyltransferase YP_193728.1 818224 D 272621 CDS YP_193729.1 58337144 3251690 818702..819742 1 NC_006814.3 hypothetical protein 819742 3251690 LBA0837 Lactobacillus acidophilus NCFM hypothetical protein YP_193729.1 818702 D 272621 CDS YP_193730.1 58337145 3251691 819798..820481 1 NC_006814.3 ComEA; competence protein 820481 3251691 LBA0838 Lactobacillus acidophilus NCFM competence protein YP_193730.1 819798 D 272621 CDS YP_193731.1 58337146 3251698 820450..822738 1 NC_006814.3 ComEC; competence protein 822738 3251698 LBA0839 Lactobacillus acidophilus NCFM competence protein YP_193731.1 820450 D 272621 CDS YP_193732.1 58337147 3251697 822735..823724 1 NC_006814.3 DNA polymerase III subunit delta 823724 3251697 LBA0840 Lactobacillus acidophilus NCFM DNA polymerase III subunit delta YP_193732.1 822735 D 272621 CDS YP_193733.1 58337148 3251699 complement(823785..824042) 1 NC_006814.3 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 824042 rpsT 3251699 rpsT Lactobacillus acidophilus NCFM 30S ribosomal protein S20 YP_193733.1 823785 R 272621 CDS YP_193734.1 58337149 3251710 824243..824389 1 NC_006814.3 RpsO; 30S ribosomal protein S15 824389 3251710 LBA0842 Lactobacillus acidophilus NCFM 30S ribosomal protein S15 YP_193734.1 824243 D 272621 CDS YP_193735.1 58337150 3251713 824655..826412 1 NC_006814.3 hypothetical protein 826412 3251713 LBA0843 Lactobacillus acidophilus NCFM hypothetical protein YP_193735.1 824655 D 272621 CDS YP_193736.1 58337151 3251712 826415..827248 1 NC_006814.3 hypothetical protein 827248 3251712 LBA0844 Lactobacillus acidophilus NCFM hypothetical protein YP_193736.1 826415 D 272621 CDS YP_193737.1 58337152 3251716 827438..828628 1 NC_006814.3 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 828628 tuf 3251716 tuf Lactobacillus acidophilus NCFM elongation factor Tu YP_193737.1 827438 D 272621 CDS YP_193738.1 58337153 3251719 828774..830102 1 NC_006814.3 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 830102 tig 3251719 tig Lactobacillus acidophilus NCFM trigger factor YP_193738.1 828774 D 272621 CDS YP_193739.1 58337154 3251727 830229..831491 1 NC_006814.3 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 831491 clpX 3251727 clpX Lactobacillus acidophilus NCFM ATP-dependent protease ATP-binding subunit ClpX YP_193739.1 830229 D 272621 CDS YP_193740.1 58337155 3251726 831481..832071 1 NC_006814.3 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 832071 engB 3251726 engB Lactobacillus acidophilus NCFM ribosome biogenesis GTP-binding protein YsxC YP_193740.1 831481 D 272621 CDS YP_193741.1 58337156 3251730 complement(832103..833107) 1 NC_006814.3 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 833107 dapF 3251730 dapF Lactobacillus acidophilus NCFM diaminopimelate epimerase YP_193741.1 832103 R 272621 CDS YP_193742.1 58337157 3251733 complement(833119..834474) 1 NC_006814.3 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; aspartate kinase 834474 3251733 LBA0850 Lactobacillus acidophilus NCFM aspartate kinase YP_193742.1 833119 R 272621 CDS YP_193743.1 58337158 3251735 834953..836260 1 NC_006814.3 diaminopimelate decarboxylase 836260 lysA 3251735 lysA Lactobacillus acidophilus NCFM diaminopimelate decarboxylase YP_193743.1 834953 D 272621 CDS YP_193744.1 58337159 3251737 836281..836991 1 NC_006814.3 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; tetrahydrodipicolinate succinylase 836991 dapD 3251737 dapD Lactobacillus acidophilus NCFM tetrahydrodipicolinate succinylase YP_193744.1 836281 D 272621 CDS YP_193745.1 58337160 3251741 836994..838145 1 NC_006814.3 amino acid amidohydrolase 838145 3251741 LBA0853 Lactobacillus acidophilus NCFM amino acid amidohydrolase YP_193745.1 836994 D 272621 CDS YP_193746.1 58337161 3251740 838151..839086 1 NC_006814.3 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 839086 3251740 LBA0854 Lactobacillus acidophilus NCFM dihydrodipicolinate synthase YP_193746.1 838151 D 272621 CDS YP_193747.1 58337162 3251743 839073..839858 1 NC_006814.3 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 839858 dapB 3251743 dapB Lactobacillus acidophilus NCFM dihydrodipicolinate reductase YP_193747.1 839073 D 272621 CDS YP_193748.1 58337163 3251746 839874..841049 1 NC_006814.3 COG0436 Aspartate-tyrosine-aromatic aminotransferase; aspartate aminotransferase 841049 3251746 LBA0856 Lactobacillus acidophilus NCFM aspartate aminotransferase YP_193748.1 839874 D 272621 CDS YP_193749.1 58337164 3251745 841049..842107 1 NC_006814.3 COG0136 Aspartate-semialdehyde dehydrogenase; aspartate-semialdehyde dehydrogenase 842107 3251745 LBA0857 Lactobacillus acidophilus NCFM aspartate-semialdehyde dehydrogenase YP_193749.1 841049 D 272621 CDS YP_193750.1 58337165 3251750 842198..843307 1 NC_006814.3 penicillin-binding protein 843307 3251750 LBA0858 Lactobacillus acidophilus NCFM penicillin-binding protein YP_193750.1 842198 D 272621 CDS YP_193751.1 58337166 3251751 complement(843344..844957) 1 NC_006814.3 hypothetical protein 844957 3251751 LBA0860 Lactobacillus acidophilus NCFM hypothetical protein YP_193751.1 843344 R 272621 CDS YP_193752.1 58337167 3251754 845299..845568 1 NC_006814.3 Polyferredoxin; polyferredoxin 845568 3251754 LBA0861 Lactobacillus acidophilus NCFM polyferredoxin YP_193752.1 845299 D 272621 CDS YP_193753.1 58337168 3251755 845582..846097 1 NC_006814.3 hypothetical protein 846097 3251755 LBA0863 Lactobacillus acidophilus NCFM hypothetical protein YP_193753.1 845582 D 272621 CDS YP_193754.1 58337169 3251757 846154..847647 1 NC_006814.3 hypothetical protein 847647 3251757 LBA0864 Lactobacillus acidophilus NCFM hypothetical protein YP_193754.1 846154 D 272621 CDS YP_193755.1 58337170 3251759 complement(847716..848642) 1 NC_006814.3 COG1957 Inosine-uridine nucleoside N-ribohydrolase; nucleoside hydrolase 848642 3251759 LBA0865 Lactobacillus acidophilus NCFM nucleoside hydrolase YP_193755.1 847716 R 272621 CDS YP_193756.1 58337171 3251761 848905..849060 1 NC_006814.3 aryl-alcohol dehydrogenase; dehydrogenase 849060 3251761 LBA0866 Lactobacillus acidophilus NCFM dehydrogenase YP_193756.1 848905 D 272621 CDS YP_193757.1 58337172 3251764 849280..850083 1 NC_006814.3 COG1396 Predicted transcriptional regulators; hypothetical protein 850083 3251764 LBA0867 Lactobacillus acidophilus NCFM hypothetical protein YP_193757.1 849280 D 272621 CDS YP_193758.1 58337173 3251766 850208..850678 1 NC_006814.3 hypothetical protein 850678 3251766 LBA0868 Lactobacillus acidophilus NCFM hypothetical protein YP_193758.1 850208 D 272621 CDS YP_193759.1 58337174 3251768 850705..850911 1 NC_006814.3 hypothetical protein 850911 3251768 LBA0869 Lactobacillus acidophilus NCFM hypothetical protein YP_193759.1 850705 D 272621 CDS YP_193762.1 58337177 3251416 complement(852052..852312) 1 NC_006814.3 COG2261 Predicted membrane protein; hypothetical protein 852312 3251416 LBA0872 Lactobacillus acidophilus NCFM hypothetical protein YP_193762.1 852052 R 272621 CDS YP_193763.1 58337178 3251772 complement(852324..852497) 1 NC_006814.3 COG3237 Uncharacterized protein conserved in bacteria; hypothetical protein 852497 3251772 LBA0873 Lactobacillus acidophilus NCFM hypothetical protein YP_193763.1 852324 R 272621 CDS YP_193764.1 58337179 3251774 complement(852717..854165) 1 NC_006814.3 phospho-beta-galactosidase I 854165 3251774 LBA0874 Lactobacillus acidophilus NCFM phospho-beta-galactosidase I YP_193764.1 852717 R 272621 CDS YP_193765.1 58337180 3251777 complement(854251..854955) 1 NC_006814.3 transcriptional regulator 854955 gntR 3251777 gntR Lactobacillus acidophilus NCFM transcriptional regulator YP_193765.1 854251 R 272621 CDS YP_193766.1 58337181 3251779 855310..855645 1 NC_006814.3 PTS system cellobiose-specific transporter subunit IIC 855645 3251779 LBA0876 Lactobacillus acidophilus NCFM PTS system cellobiose-specific transporter subunit IIC YP_193766.1 855310 D 272621 CDS YP_193767.1 58337182 3251781 855671..856042 1 NC_006814.3 cellobiose PTS, EIIA; PTS system cellobiose-specific transporter subunit IIA 856042 3251781 LBA0877 Lactobacillus acidophilus NCFM PTS system cellobiose-specific transporter subunit IIA YP_193767.1 855671 D 272621 CDS YP_193768.1 58337183 3251784 856152..856658 1 NC_006814.3 hypothetical protein 856658 3251784 LBA0878 Lactobacillus acidophilus NCFM hypothetical protein YP_193768.1 856152 D 272621 CDS YP_193769.1 58337184 3251786 857012..857782 1 NC_006814.3 PTS system cellobiose-specific transporter subunit IIC 857782 3251786 LBA0879 Lactobacillus acidophilus NCFM PTS system cellobiose-specific transporter subunit IIC YP_193769.1 857012 D 272621 CDS YP_193770.1 58337185 3251788 complement(857885..858295) 1 NC_006814.3 hypothetical protein 858295 3251788 LBA0880 Lactobacillus acidophilus NCFM hypothetical protein YP_193770.1 857885 R 272621 CDS YP_193771.1 58337186 3251790 complement(858384..859865) 1 NC_006814.3 COG2723 Beta-glucosidase-6-phospho-beta-glucosidase-beta- galactosidase; phospho-beta-glucosidase 859865 3251790 LBA0881 Lactobacillus acidophilus NCFM phospho-beta-glucosidase YP_193771.1 858384 R 272621 CDS YP_193772.1 58337187 3251794 complement(859875..860597) 1 NC_006814.3 transcriptional regulator 860597 gntR 3251794 gntR Lactobacillus acidophilus NCFM transcriptional regulator YP_193772.1 859875 R 272621 CDS YP_193773.1 58337188 3251793 complement(860739..860984) 1 NC_006814.3 reverse transcriptase homolog; hypothetical protein 860984 3251793 LBA0883 Lactobacillus acidophilus NCFM hypothetical protein YP_193773.1 860739 R 272621 CDS YP_193774.1 58337189 3251797 complement(861033..862460) 1 NC_006814.3 PTS system cellobiose-specific transporter subunit IIC 862460 3251797 LBA0884 Lactobacillus acidophilus NCFM PTS system cellobiose-specific transporter subunit IIC YP_193774.1 861033 R 272621 CDS YP_193775.1 58337190 3251796 complement(862460..863842) 1 NC_006814.3 COG2723 Beta-glucosidase-6-phospho-beta-glucosidase -beta-galactosidase; beta-glucosidase 863842 3251796 LBA0885 Lactobacillus acidophilus NCFM beta-glucosidase YP_193775.1 862460 R 272621 CDS YP_193776.1 58337191 3251799 complement(864028..864912) 1 NC_006814.3 COG1940 transcriptional regulator-sugar kinase; sugar kinase 864912 3251799 LBA0886 Lactobacillus acidophilus NCFM sugar kinase YP_193776.1 864028 R 272621 CDS YP_193777.1 58337192 3251800 865032..865520 1 NC_006814.3 hypothetical protein 865520 3251800 LBA0887 Lactobacillus acidophilus NCFM hypothetical protein YP_193777.1 865032 D 272621 CDS YP_193778.1 58337193 3251803 865595..866191 1 NC_006814.3 hypothetical protein 866191 3251803 LBA0888 Lactobacillus acidophilus NCFM hypothetical protein YP_193778.1 865595 D 272621 CDS YP_193779.1 58337194 3251804 complement(866241..867527) 1 NC_006814.3 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 867527 eno 3251804 eno Lactobacillus acidophilus NCFM phosphopyruvate hydratase YP_193779.1 866241 R 272621 CDS YP_193780.1 58337195 3251806 867753..868586 1 NC_006814.3 hypothetical protein 868586 3251806 LBA0890 Lactobacillus acidophilus NCFM hypothetical protein YP_193780.1 867753 D 272621 CDS YP_193781.1 58337196 3251808 complement(868637..869212) 1 NC_006814.3 COG0671 Membrane-associated phospholipid phosphatase; hypothetical protein 869212 3251808 LBA0891 Lactobacillus acidophilus NCFM hypothetical protein YP_193781.1 868637 R 272621 CDS YP_193782.1 58337197 3251811 complement(869317..870294) 1 NC_006814.3 bile salt hydrolase 870294 bshA 3251811 bshA Lactobacillus acidophilus NCFM bile salt hydrolase YP_193782.1 869317 R 272621 CDS YP_193783.1 58337198 3251813 complement(870710..871660) 1 NC_006814.3 phage related protein; integrase 871660 3251813 LBA0893 Lactobacillus acidophilus NCFM integrase YP_193783.1 870710 R 272621 CDS YP_193784.1 58337199 3251817 complement(871880..872080) 1 NC_006814.3 hypothetical protein 872080 3251817 LBA0894 Lactobacillus acidophilus NCFM hypothetical protein YP_193784.1 871880 R 272621 CDS YP_193785.1 58337200 3251820 complement(872083..872736) 1 NC_006814.3 potential frameshift to 894; capsid protein 872736 3251820 LBA0895 Lactobacillus acidophilus NCFM capsid protein YP_193785.1 872083 R 272621 CDS YP_193786.1 58337201 3251823 complement(873265..873603) 1 NC_006814.3 repressor; transcriptional regulator 873603 3251823 LBA0896 Lactobacillus acidophilus NCFM transcriptional regulator YP_193786.1 873265 R 272621 CDS YP_193787.1 58337202 3251825 873767..873970 1 NC_006814.3 Cro-like protein 873970 3251825 LBA0897 Lactobacillus acidophilus NCFM Cro-like protein YP_193787.1 873767 D 272621 CDS YP_193788.1 58337203 3251827 874230..875621 1 NC_006814.3 transporter protein 875621 3251827 LBA0899 Lactobacillus acidophilus NCFM transporter protein YP_193788.1 874230 D 272621 CDS YP_193789.1 58337204 3251830 875749..876705 1 NC_006814.3 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 876705 thyA 3251830 thyA Lactobacillus acidophilus NCFM thymidylate synthase YP_193789.1 875749 D 272621 CDS YP_193790.1 58337205 3251831 876715..877218 1 NC_006814.3 COG0262 Dihydrofolate reductase; dihydrofolate reductase 877218 dfrA 3251831 dfrA Lactobacillus acidophilus NCFM dihydrofolate reductase YP_193790.1 876715 D 272621 CDS YP_193791.1 58337206 3251833 877297..879717 1 NC_006814.3 COG0474 Cation transport ATPase; cation-transporting atpase 879717 3251833 LBA0903 Lactobacillus acidophilus NCFM cation-transporting atpase YP_193791.1 877297 D 272621 CDS YP_193792.1 58337207 3251835 880089..880943 1 NC_006814.3 OM lipoprotein 880943 3251835 LBA0904 Lactobacillus acidophilus NCFM OM lipoprotein YP_193792.1 880089 D 272621 CDS YP_193793.1 58337208 3251837 880958..882019 1 NC_006814.3 ABC transporter ATP-binding protein 882019 3251837 LBA0905 Lactobacillus acidophilus NCFM ABC transporter ATP-binding protein YP_193793.1 880958 D 272621 CDS YP_193794.1 58337209 3251840 882012..882713 1 NC_006814.3 ABC transporter -permease 882713 3251840 LBA0906 Lactobacillus acidophilus NCFM ABC transporter -permease YP_193794.1 882012 D 272621 CDS YP_193795.1 58337210 3251843 882913..884316 1 NC_006814.3 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 884316 fumC 3251843 fumC Lactobacillus acidophilus NCFM fumarate hydratase YP_193795.1 882913 D 272621 CDS YP_193796.1 58337211 3251845 884330..885712 1 NC_006814.3 fumarate reductase flavoprotein subunit 885712 3251845 LBA0908 Lactobacillus acidophilus NCFM fumarate reductase flavoprotein subunit YP_193796.1 884330 D 272621 CDS YP_193797.1 58337212 3251848 885868..887394 1 NC_006814.3 mucus binding protein 887394 3251848 LBA0909 Lactobacillus acidophilus NCFM mucus binding protein YP_193797.1 885868 D 272621 CDS YP_193798.1 58337213 3251850 887481..888407 1 NC_006814.3 Converts (S)-lactate and NAD(+) to pyruvate and NADH; L-lactate dehydrogenase 888407 ldh 3251850 ldh Lactobacillus acidophilus NCFM L-lactate dehydrogenase YP_193798.1 887481 D 272621 CDS YP_193799.1 58337214 3251853 888536..889849 1 NC_006814.3 COG3579 Aminopeptidase C; aminopeptidase 889849 3251853 LBA0911 Lactobacillus acidophilus NCFM aminopeptidase YP_193799.1 888536 D 272621 CDS YP_193800.1 58337215 3251856 890101..891567 1 NC_006814.3 cation transport protein; 2-oxoglutarate-malate translocator 891567 3251856 LBA0912 Lactobacillus acidophilus NCFM 2-oxoglutarate-malate translocator YP_193800.1 890101 D 272621 CDS YP_193801.1 58337216 3251858 891644..892435 1 NC_006814.3 halo peroxidase; hydrolase 892435 3251858 LBA0913 Lactobacillus acidophilus NCFM hydrolase YP_193801.1 891644 D 272621 CDS YP_193802.1 58337217 3251860 892525..893580 1 NC_006814.3 citrate (pro-3S)-lyase ligase; citrate lyase ligase 893580 citC 3251860 citC Lactobacillus acidophilus NCFM citrate lyase ligase YP_193802.1 892525 D 272621 CDS YP_193803.1 58337218 3251862 893570..893863 1 NC_006814.3 acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma 893863 citD 3251862 citD Lactobacillus acidophilus NCFM citrate lyase subunit gamma YP_193803.1 893570 D 272621 CDS YP_193804.1 58337219 3251864 893863..894777 1 NC_006814.3 citrate lyase subunit beta 894777 citE 3251864 citE Lactobacillus acidophilus NCFM citrate lyase subunit beta YP_193804.1 893863 D 272621 CDS YP_193805.1 58337220 3251866 894767..896308 1 NC_006814.3 citrate lyase, alpha chain; citrate lyase subunit alpha 896308 citF 3251866 citF Lactobacillus acidophilus NCFM citrate lyase subunit alpha YP_193805.1 894767 D 272621 CDS YP_193806.1 58337221 3251868 896280..896414 1 NC_006814.3 hypothetical protein 896414 citG 3251868 citG Lactobacillus acidophilus NCFM hypothetical protein YP_193806.1 896280 D 272621 CDS YP_193807.1 58337222 3251870 896551..897006 1 NC_006814.3 integral membrane protein; hypothetical protein 897006 3251870 LBA0919 Lactobacillus acidophilus NCFM hypothetical protein YP_193807.1 896551 D 272621 CDS YP_193808.1 58337223 3251872 complement(897211..898044) 1 NC_006814.3 ABC transporter permease 898044 3251872 LBA0920 Lactobacillus acidophilus NCFM ABC transporter permease YP_193808.1 897211 R 272621 CDS YP_193809.1 58337224 3251873 complement(898045..899745) 1 NC_006814.3 ABC transporter ATP-binding protein 899745 3251873 LBA0921 Lactobacillus acidophilus NCFM ABC transporter ATP-binding protein YP_193809.1 898045 R 272621 CDS YP_193810.1 58337225 3251876 complement(899757..900314) 1 NC_006814.3 COG4720 Predicted membrane protein; hypothetical protein 900314 3251876 LBA0922 Lactobacillus acidophilus NCFM hypothetical protein YP_193810.1 899757 R 272621 CDS YP_193811.1 58337226 3251880 900465..900836 1 NC_006814.3 hypothetical protein 900836 3251880 LBA0923 Lactobacillus acidophilus NCFM hypothetical protein YP_193811.1 900465 D 272621 CDS YP_193812.1 58337227 3251882 complement(900864..901196) 1 NC_006814.3 copper-transporting P-type ATPase; transporter protein 901196 3251882 LBA0924 Lactobacillus acidophilus NCFM transporter protein YP_193812.1 900864 R 272621 CDS YP_193813.1 58337228 3251884 complement(901252..902190) 1 NC_006814.3 citrate lyase regulator; transcriptional regulator 902190 3251884 LBA0925 Lactobacillus acidophilus NCFM transcriptional regulator YP_193813.1 901252 R 272621 CDS YP_193814.1 58337229 3251888 902369..903724 1 NC_006814.3 COG2966 Uncharacterized conserved protein; hypothetical protein 903724 3251888 LBA0927 Lactobacillus acidophilus NCFM hypothetical protein YP_193814.1 902369 D 272621 CDS YP_193815.1 58337230 3251889 complement(903774..903857) 1 NC_006814.3 hypothetical protein 903857 3251889 LBA0928 Lactobacillus acidophilus NCFM hypothetical protein YP_193815.1 903774 R 272621 CDS YP_193816.1 58337231 3251891 complement(903959..904468) 1 NC_006814.3 COG2606 Uncharacterized conserved protein; transcriptional regulator 904468 3251891 LBA0930 Lactobacillus acidophilus NCFM transcriptional regulator YP_193816.1 903959 R 272621 CDS YP_193817.1 58337232 3251895 904529..905473 1 NC_006814.3 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 905473 prmA 3251895 prmA Lactobacillus acidophilus NCFM 50S ribosomal protein L11 methyltransferase YP_193817.1 904529 D 272621 CDS YP_193818.1 58337233 3251898 905906..908146 1 NC_006814.3 RelA; COG0317 Guanosine polyphosphate pyrophosphohydrolases-synthetases; ppGpp synthetase 908146 relA 3251898 relA Lactobacillus acidophilus NCFM ppGpp synthetase YP_193818.1 905906 D 272621 CDS YP_193819.1 58337234 3251900 908146..908583 1 NC_006814.3 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 908583 3251900 LBA0933 Lactobacillus acidophilus NCFM D-tyrosyl-tRNA(Tyr) deacylase YP_193819.1 908146 D 272621 CDS YP_193820.1 58337235 3251902 908875..910161 1 NC_006814.3 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 910161 hisS 3251902 hisS Lactobacillus acidophilus NCFM histidyl-tRNA synthetase YP_193820.1 908875 D 272621 CDS YP_193821.1 58337236 3251904 910169..912013 1 NC_006814.3 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 912013 aspS 3251904 aspS Lactobacillus acidophilus NCFM aspartyl-tRNA synthetase YP_193821.1 910169 D 272621 CDS YP_193822.1 58337237 3251905 complement(912079..913263) 1 NC_006814.3 PLP-dependent aminotransferase; aromatic amino acid transferase 913263 3251905 LBA0937 Lactobacillus acidophilus NCFM aromatic amino acid transferase YP_193822.1 912079 R 272621 CDS YP_193823.1 58337238 3251909 913420..914613 1 NC_006814.3 COG0452 Phosphopantothenoylcysteine synthetase-decarboxylase; pantothenate metabolism flavoprotein-like protein 914613 3251909 LBA0939 Lactobacillus acidophilus NCFM pantothenate metabolism flavoprotein-like protein YP_193823.1 913420 D 272621 CDS YP_193824.1 58337239 3251911 914944..915759 1 NC_006814.3 oxidoreductase, aldo-keto reductase; reductase-dehydrogenase 915759 3251911 LBA0940 Lactobacillus acidophilus NCFM reductase-dehydrogenase YP_193824.1 914944 D 272621 CDS YP_193825.1 58337240 3251914 915811..916623 1 NC_006814.3 cof family protein 916623 3251914 LBA0941 Lactobacillus acidophilus NCFM cof family protein YP_193825.1 915811 D 272621 CDS YP_193826.1 58337241 3251916 916690..917655 1 NC_006814.3 glyoxylate reductase 917655 3251916 LBA0942 Lactobacillus acidophilus NCFM glyoxylate reductase YP_193826.1 916690 D 272621 CDS YP_193827.1 58337242 3251918 complement(917690..918886) 1 NC_006814.3 COG0531 Amino acid transporters; cationic amino acid transporter 918886 3251918 LBA0943 Lactobacillus acidophilus NCFM cationic amino acid transporter YP_193827.1 917690 R 272621 CDS YP_193828.1 58337243 3251920 complement(919173..919787) 1 NC_006814.3 COG0586 Uncharacterized membrane-associated protein; alkaline phosphatase 919787 3251920 LBA0945 Lactobacillus acidophilus NCFM alkaline phosphatase YP_193828.1 919173 R 272621 CDS YP_193829.1 58337244 3251923 919923..921725 1 NC_006814.3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 921725 uvrC 3251923 uvrC Lactobacillus acidophilus NCFM excinuclease ABC subunit C YP_193829.1 919923 D 272621 CDS YP_193830.1 58337245 3251926 921804..923105 1 NC_006814.3 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 923105 obgE 3251926 obgE Lactobacillus acidophilus NCFM GTPase ObgE YP_193830.1 921804 D 272621 CDS YP_193831.1 58337246 3251928 923251..925044 1 NC_006814.3 COG1835 Predicted acyltransferases; inner membrane trans-acylase 925044 3251928 LBA0948 Lactobacillus acidophilus NCFM inner membrane trans-acylase YP_193831.1 923251 D 272621 CDS YP_193832.1 58337247 3251931 925065..926003 1 NC_006814.3 metallo-beta-lactamase superfamily 926003 3251931 LBA0949 Lactobacillus acidophilus NCFM metallo-beta-lactamase superfamily YP_193832.1 925065 D 272621 CDS YP_193833.1 58337248 3251933 926000..926794 1 NC_006814.3 oxidoreductase 926794 3251933 LBA0950 Lactobacillus acidophilus NCFM oxidoreductase YP_193833.1 926000 D 272621 CDS YP_193834.1 58337249 3251934 926800..927045 1 NC_006814.3 hypothetical protein 927045 3251934 LBA0951 Lactobacillus acidophilus NCFM hypothetical protein YP_193834.1 926800 D 272621 CDS YP_193835.1 58337250 3251937 927150..927338 1 NC_006814.3 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 927338 rpmF 3251937 rpmF Lactobacillus acidophilus NCFM 50S ribosomal protein L32 YP_193835.1 927150 D 272621 CDS YP_193836.1 58337251 3251940 927396..928952 1 NC_006814.3 2',3'-cyclic-nucleotide 2'-phosphodiesterase 928952 yfkN 3251940 yfkN Lactobacillus acidophilus NCFM 2',3'-cyclic-nucleotide 2'-phosphodiesterase YP_193836.1 927396 D 272621 CDS YP_193837.1 58337252 3251941 complement(929014..929232) 1 NC_006814.3 integral membrane protein; hypothetical protein 929232 3251941 LBA0954 Lactobacillus acidophilus NCFM hypothetical protein YP_193837.1 929014 R 272621 CDS YP_193838.1 58337253 3251945 929349..932456 1 NC_006814.3 DNA polymerase III subunit alpha 932456 3251945 LBA0955 Lactobacillus acidophilus NCFM DNA polymerase III subunit alpha YP_193838.1 929349 D 272621 CDS YP_193839.1 58337254 3251947 932623..933585 1 NC_006814.3 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 933585 3251947 LBA0956 Lactobacillus acidophilus NCFM 6-phosphofructokinase YP_193839.1 932623 D 272621 CDS YP_193840.1 58337255 3251950 933614..935383 1 NC_006814.3 COG3848 Phosphohistidine swiveling domain; pyruvate kinase 935383 kpyK 3251950 kpyK Lactobacillus acidophilus NCFM pyruvate kinase YP_193840.1 933614 D 272621 CDS YP_193841.1 58337256 3251951 935507..936397 1 NC_006814.3 hypothetical protein 936397 3251951 LBA0958 Lactobacillus acidophilus NCFM hypothetical protein YP_193841.1 935507 D 272621 CDS YP_193842.1 58337257 3251953 936387..937292 1 NC_006814.3 XerD; COG4974 Site-specific recombinase XerD; integrase-recombinase 937292 xerD 3251953 xerD Lactobacillus acidophilus NCFM integrase-recombinase YP_193842.1 936387 D 272621 CDS YP_193843.1 58337258 3251955 937302..937664 1 NC_006814.3 RibT; hypothetical protein; reductase 937664 ribT 3251955 ribT Lactobacillus acidophilus NCFM reductase YP_193843.1 937302 D 272621 CDS YP_193844.1 58337259 3251957 937651..938391 1 NC_006814.3 COG1354 Uncharacterized conserved protein; hypothetical protein 938391 3251957 LBA0961 Lactobacillus acidophilus NCFM hypothetical protein YP_193844.1 937651 D 272621 CDS YP_193845.1 58337260 3251959 938381..938974 1 NC_006814.3 hypothetical protein 938974 3251959 LBA0962 Lactobacillus acidophilus NCFM hypothetical protein YP_193845.1 938381 D 272621 CDS YP_193846.1 58337261 3251961 938974..939690 1 NC_006814.3 ribosomal large subunit pseudouridine synthase B 939690 rluB 3251961 rluB Lactobacillus acidophilus NCFM ribosomal large subunit pseudouridine synthase B YP_193846.1 938974 D 272621 CDS YP_193847.1 58337262 3251964 939914..940603 1 NC_006814.3 COG3601 Predicted membrane protein; hypothetical protein 940603 3251964 LBA0965 Lactobacillus acidophilus NCFM hypothetical protein YP_193847.1 939914 D 272621 CDS YP_193848.1 58337263 3251966 940704..941165 1 NC_006814.3 N-acetylmuramidase 941165 3251966 LBA0966 Lactobacillus acidophilus NCFM N-acetylmuramidase YP_193848.1 940704 D 272621 CDS YP_193849.1 58337264 3251968 941216..941878 1 NC_006814.3 COG0283 Cytidylate kinase; cytidin monophosphate kinase 941878 3251968 LBA0967 Lactobacillus acidophilus NCFM cytidin monophosphate kinase YP_193849.1 941216 D 272621 CDS YP_193850.1 58337265 3251971 941963..943174 1 NC_006814.3 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 943174 rpsA 3251971 rpsA Lactobacillus acidophilus NCFM 30S ribosomal protein S1 YP_193850.1 941963 D 272621 CDS YP_193851.1 58337266 3251973 943260..944567 1 NC_006814.3 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 944567 engA 3251973 engA Lactobacillus acidophilus NCFM GTP-binding protein EngA YP_193851.1 943260 D 272621 CDS YP_193852.1 58337267 3251975 944731..945006 1 NC_006814.3 DNA-binding protein II HB 945006 3251975 LBA0970 Lactobacillus acidophilus NCFM DNA-binding protein II HB YP_193852.1 944731 D 272621 CDS YP_193853.1 58337268 3251978 945094..946341 1 NC_006814.3 GlcNAc; hypothetical protein; O-linked transferase 946341 3251978 LBA0971 Lactobacillus acidophilus NCFM O-linked transferase YP_193853.1 945094 D 272621 CDS YP_193854.1 58337269 3251979 complement(946374..947261) 1 NC_006814.3 COG1284 Uncharacterized conserved protein; hypothetical protein 947261 3251979 LBA0972 Lactobacillus acidophilus NCFM hypothetical protein YP_193854.1 946374 R 272621 CDS YP_193855.1 58337270 3251982 947345..948544 1 NC_006814.3 catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity; tRNA CCA-pyrophosphorylase 948544 3251982 LBA0973 Lactobacillus acidophilus NCFM tRNA CCA-pyrophosphorylase YP_193855.1 947345 D 272621 CDS YP_193856.1 58337271 3251984 complement(948584..949249) 1 NC_006814.3 channel-forming protein 949249 3251984 LBA0974 Lactobacillus acidophilus NCFM channel-forming protein YP_193856.1 948584 R 272621 CDS YP_193857.1 58337272 3251987 949369..950220 1 NC_006814.3 DegV; family protein 950220 3251987 LBA0975 Lactobacillus acidophilus NCFM family protein YP_193857.1 949369 D 272621 CDS YP_193858.1 58337273 3251989 950223..950453 1 NC_006814.3 COG4479 Uncharacterized protein conserved in bacteria; hypothetical protein 950453 3251989 LBA0976 Lactobacillus acidophilus NCFM hypothetical protein YP_193858.1 950223 D 272621 CDS YP_193859.1 58337274 3251991 950498..952099 1 NC_006814.3 Na(+)-H(+) antiporter; Na+-H+ antiporter 952099 3251991 LBA0977 Lactobacillus acidophilus NCFM Na+-H+ antiporter YP_193859.1 950498 D 272621 CDS YP_193860.1 58337275 3251993 952133..952987 1 NC_006814.3 COG1161 Predicted GTPases; GTP binding protein 952987 3251993 LBA0978 Lactobacillus acidophilus NCFM GTP binding protein YP_193860.1 952133 D 272621 CDS YP_193861.1 58337276 3251995 952977..953729 1 NC_006814.3 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 953729 rnhB 3251995 rnhB Lactobacillus acidophilus NCFM ribonuclease HII YP_193861.1 952977 D 272621 CDS YP_193862.1 58337277 3251997 953791..954648 1 NC_006814.3 SMF family; DNA processing protein subunit A 954648 3251997 LBA0980 Lactobacillus acidophilus NCFM DNA processing protein subunit A YP_193862.1 953791 D 272621 CDS YP_193863.1 58337278 3252000 954709..956826 1 NC_006814.3 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 956826 3252000 LBA0981 Lactobacillus acidophilus NCFM DNA topoisomerase I YP_193863.1 954709 D 272621 CDS YP_193864.1 58337279 3252002 956853..958169 1 NC_006814.3 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; tRNA (uracil-5-)-methyltransferase Gid 958169 gidA 3252002 gidA Lactobacillus acidophilus NCFM tRNA (uracil-5-)-methyltransferase Gid YP_193864.1 956853 D 272621 CDS YP_193865.1 58337280 3252004 958169..959077 1 NC_006814.3 XerC; COG4974 Site-specific recombinase XerD; integrase-recombinase 959077 xerC 3252004 xerC Lactobacillus acidophilus NCFM integrase-recombinase YP_193865.1 958169 D 272621 CDS YP_193866.1 58337281 3252005 959087..959611 1 NC_006814.3 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 959611 hslV 3252005 hslV Lactobacillus acidophilus NCFM ATP-dependent protease peptidase subunit YP_193866.1 959087 D 272621 CDS YP_193867.1 58337282 3252008 959623..961023 1 NC_006814.3 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 961023 hslU 3252008 hslU Lactobacillus acidophilus NCFM ATP-dependent protease ATP-binding subunit HslU YP_193867.1 959623 D 272621 CDS YP_193868.1 58337283 3252009 961181..962080 1 NC_006814.3 galactose mutarotase related enzyme 962080 3252009 LBA0986 Lactobacillus acidophilus NCFM galactose mutarotase related enzyme YP_193868.1 961181 D 272621 CDS YP_193869.1 58337284 3252010 complement(962250..962654) 1 NC_006814.3 hypothetical protein 962654 3252010 LBA0987 Lactobacillus acidophilus NCFM hypothetical protein YP_193869.1 962250 R 272621 CDS YP_193870.1 58337285 3252183 962839..964125 1 NC_006814.3 PTS system lactose-specific transporter subunit IIBC 964125 lacE 3252183 lacE Lactobacillus acidophilus NCFM PTS system lactose-specific transporter subunit IIBC YP_193870.1 962839 D 272621 CDS YP_193871.1 58337286 3252071 964122..964976 1 NC_006814.3 hydrolase 964976 3252071 LBA0990 Lactobacillus acidophilus NCFM hydrolase YP_193871.1 964122 D 272621 CDS YP_193872.1 58337287 3252074 complement(965003..965815) 1 NC_006814.3 XerD; hypothetical protein; integrase-recombinase 965815 xerD 3252074 xerD Lactobacillus acidophilus NCFM integrase-recombinase YP_193872.1 965003 R 272621 CDS YP_193873.1 58337288 3252061 966034..966423 1 NC_006814.3 CrcB; hypothetical protein 966423 crcB 3252061 crcB Lactobacillus acidophilus NCFM hypothetical protein YP_193873.1 966034 D 272621 CDS YP_193874.1 58337289 3252079 966425..966799 1 NC_006814.3 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 966799 crcB 3252079 crcB Lactobacillus acidophilus NCFM camphor resistance protein CrcB YP_193874.1 966425 D 272621 CDS YP_193875.1 58337290 3252090 complement(966844..968247) 1 NC_006814.3 divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases; dipeptidase PepV 968247 pepD 3252090 pepD Lactobacillus acidophilus NCFM dipeptidase PepV YP_193875.1 966844 R 272621 CDS YP_193876.1 58337291 3252082 complement(968367..969839) 1 NC_006814.3 COG0531 Amino acid transporters; amino acid permease 969839 3252082 LBA0995 Lactobacillus acidophilus NCFM amino acid permease YP_193876.1 968367 R 272621 CDS YP_193877.1 58337292 3252092 970077..972170 1 NC_006814.3 COG1982 Arginine-lysine-ornithine decarboxylases; ornithine decarboxylase subunit A 972170 3252092 LBA0996 Lactobacillus acidophilus NCFM ornithine decarboxylase subunit A YP_193877.1 970077 D 272621 CDS YP_193878.1 58337293 3252131 972197..973459 1 NC_006814.3 aluminum resistance protein 973459 3252131 LBA0997 Lactobacillus acidophilus NCFM aluminum resistance protein YP_193878.1 972197 D 272621 CDS YP_193879.1 58337294 3252174 complement(973896..974567) 1 NC_006814.3 NAD+ binding protein for K+transport 974567 3252174 LBA0998 Lactobacillus acidophilus NCFM NAD+ binding protein for K+transport YP_193879.1 973896 R 272621 CDS YP_193880.1 58337295 3252179 complement(974560..975900) 1 NC_006814.3 Na+-transporting ATP synthase 975900 3252179 LBA0999 Lactobacillus acidophilus NCFM Na+-transporting ATP synthase YP_193880.1 974560 R 272621 CDS YP_193881.1 58337296 3252199 976061..977833 1 NC_006814.3 RecQ; ATP-dependent DNA helicase 977833 recQ 3252199 recQ Lactobacillus acidophilus NCFM ATP-dependent DNA helicase YP_193881.1 976061 D 272621 CDS YP_193882.1 58337297 3252217 977918..978370 1 NC_006814.3 conserved hypothetical protein; trp repressor binding protein 978370 3252217 LBA1001 Lactobacillus acidophilus NCFM trp repressor binding protein YP_193882.1 977918 D 272621 CDS YP_193883.1 58337298 3252242 978443..980977 1 NC_006814.3 excinuclease subunit A 980977 3252242 LBA1002 Lactobacillus acidophilus NCFM excinuclease subunit A YP_193883.1 978443 D 272621 CDS YP_193884.1 58337299 3252151 981037..981969 1 NC_006814.3 converts homocysteine and S-adenosyl-methionine to methionine and S-adenosyl-homocysteine or S-methyl-methionine and homocysteine to two methionines; homocysteine methyltransferase 981969 mmuM 3252151 mmuM Lactobacillus acidophilus NCFM homocysteine methyltransferase YP_193884.1 981037 D 272621 CDS YP_193885.1 58337300 3252209 complement(982276..982908) 1 NC_006814.3 COG0671 Membrane-associated phospholipid phosphatase; hypothetical protein 982908 3252209 LBA1004 Lactobacillus acidophilus NCFM hypothetical protein YP_193885.1 982276 R 272621 CDS YP_193886.1 58337301 3252228 983001..983390 1 NC_006814.3 protein acetyltransferase; acetyltransferase 983390 3252228 LBA1005 Lactobacillus acidophilus NCFM acetyltransferase YP_193886.1 983001 D 272621 CDS YP_193887.1 58337302 3252237 983581..984675 1 NC_006814.3 penicillin-binding protein 984675 3252237 LBA1006 Lactobacillus acidophilus NCFM penicillin-binding protein YP_193887.1 983581 D 272621 CDS YP_193888.1 58337303 3252247 984730..985578 1 NC_006814.3 COG2240 Pyridoxal-pyridoxine-pyridoxamine kinase; pyridoxal kinase 985578 3252247 LBA1007 Lactobacillus acidophilus NCFM pyridoxal kinase YP_193888.1 984730 D 272621 CDS YP_193889.1 58337304 3252261 985592..986149 1 NC_006814.3 hypothetical protein 986149 3252261 LBA1008 Lactobacillus acidophilus NCFM hypothetical protein YP_193889.1 985592 D 272621 CDS YP_193890.1 58337305 3252254 986253..987458 1 NC_006814.3 hypothetical protein 987458 3252254 LBA1010 Lactobacillus acidophilus NCFM hypothetical protein YP_193890.1 986253 D 272621 CDS YP_193891.1 58337306 3252308 987582..988988 1 NC_006814.3 hypothetical protein 988988 3252308 LBA1011 Lactobacillus acidophilus NCFM hypothetical protein YP_193891.1 987582 D 272621 CDS YP_193892.1 58337307 3252320 complement(989171..991102) 1 NC_006814.3 COG1263 Phosphotransferase system IIC components, glucose-maltose-N-acetylglucosamine-specific; PTS system trehalose specific transporter subunit AIIBC 991102 treB 3252320 treB Lactobacillus acidophilus NCFM PTS system trehalose specific transporter subunit AIIBC YP_193892.1 989171 R 272621 CDS YP_193893.1 58337308 3252349 991285..992010 1 NC_006814.3 COG2188 transcriptional regulators; trehalose operon transcriptional repressor 992010 treR 3252349 treR Lactobacillus acidophilus NCFM trehalose operon transcriptional repressor YP_193893.1 991285 D 272621 CDS YP_193894.1 58337309 3252334 992021..993685 1 NC_006814.3 trehalose 6-P hydrolase 993685 treC 3252334 treC Lactobacillus acidophilus NCFM trehalose 6-P hydrolase YP_193894.1 992021 D 272621 CDS YP_193895.1 58337310 3252336 complement(993847..994587) 1 NC_006814.3 type 1 capsular polysaccharide biosynthesis protein 994587 3252336 LBA1015 Lactobacillus acidophilus NCFM type 1 capsular polysaccharide biosynthesis protein YP_193895.1 993847 R 272621 CDS YP_193896.1 58337311 3252341 995031..995588 1 NC_006814.3 potential frameshift to 1019; mucus binding protein 995588 3252341 LBA1016 Lactobacillus acidophilus NCFM mucus binding protein YP_193896.1 995031 D 272621 CDS YP_193897.1 58337312 3252348 995548..996432 1 NC_006814.3 potential frameshift to 1019; mucus binding protein 996432 3252348 LBA1017 Lactobacillus acidophilus NCFM mucus binding protein YP_193897.1 995548 D 272621 CDS YP_193898.1 58337313 3252351 997153..998193 1 NC_006814.3 potential frameshift to 1019; hypothetical protein; mucus binding protein 998193 3252351 LBA1018 Lactobacillus acidophilus NCFM mucus binding protein YP_193898.1 997153 D 272621 CDS YP_193899.1 58337314 3252337 998965..1006917 1 NC_006814.3 potential frameshift to 1016; mucus binding protein 1006917 3252337 LBA1019 Lactobacillus acidophilus NCFM mucus binding protein YP_193899.1 998965 D 272621 CDS YP_193900.1 58337315 3252355 1007250..1014182 1 NC_006814.3 mucus binding protein 1014182 3252355 LBA1020 Lactobacillus acidophilus NCFM mucus binding protein YP_193900.1 1007250 D 272621 CDS YP_193901.1 58337316 3252360 complement(1014163..1014354) 1 NC_006814.3 transcriptional regulator of multidrug-efflux transporter genes; transcriptional regulator 1014354 3252360 LBA1021 Lactobacillus acidophilus NCFM transcriptional regulator YP_193901.1 1014163 R 272621 CDS YP_193902.1 58337317 3252387 1014416..1015279 1 NC_006814.3 arginase 1015279 3252387 LBA1022 Lactobacillus acidophilus NCFM arginase YP_193902.1 1014416 D 272621 CDS YP_193903.1 58337318 3252389 1015365..1016003 1 NC_006814.3 COG0702 Predicted nucleoside-diphosphate-sugar epimerases; oxidoreductase 1016003 3252389 LBA1023 Lactobacillus acidophilus NCFM oxidoreductase YP_193903.1 1015365 D 272621 CDS YP_193904.1 58337319 3252369 complement(1016062..1016928) 1 NC_006814.3 transcriptional regulator 1016928 lysR 3252369 lysR Lactobacillus acidophilus NCFM transcriptional regulator YP_193904.1 1016062 R 272621 CDS YP_193905.1 58337320 3252404 1017041..1017901 1 NC_006814.3 aldo/keto reductase 1017901 3252404 LBA1025 Lactobacillus acidophilus NCFM aldo/keto reductase YP_193905.1 1017041 D 272621 CDS YP_193906.1 58337321 3252422 1017922..1018791 1 NC_006814.3 aldo/keto reductase 1018791 3252422 LBA1026 Lactobacillus acidophilus NCFM aldo/keto reductase YP_193906.1 1017922 D 272621 CDS YP_193907.1 58337322 3252431 1019042..1019899 1 NC_006814.3 oxidoreductase 1019899 3252431 LBA1027 Lactobacillus acidophilus NCFM oxidoreductase YP_193907.1 1019042 D 272621 CDS YP_193908.1 58337323 3252402 1020160..1021317 1 NC_006814.3 surface layer protein 1021317 3252402 LBA1029 Lactobacillus acidophilus NCFM surface layer protein YP_193908.1 1020160 D 272621 CDS YP_193909.1 58337324 3252441 1021535..1022068 1 NC_006814.3 acetyl transferase; streptothricine-acetyl-transferase 1022068 3252441 LBA1030 Lactobacillus acidophilus NCFM streptothricine-acetyl-transferase YP_193909.1 1021535 D 272621 CDS YP_193910.1 58337325 3252469 1022290..1022883 1 NC_006814.3 serine-specific protein kinase 1022883 3252469 LBA1031 Lactobacillus acidophilus NCFM serine-specific protein kinase YP_193910.1 1022290 D 272621 CDS YP_193911.1 58337326 3252475 1022922..1023332 1 NC_006814.3 hypothetical protein 1023332 3252475 LBA1032 Lactobacillus acidophilus NCFM hypothetical protein YP_193911.1 1022922 D 272621 CDS YP_193912.1 58337327 3252472 1023482..1024054 1 NC_006814.3 conserved domain protein; hypothetical protein 1024054 3252472 LBA1033 Lactobacillus acidophilus NCFM hypothetical protein YP_193912.1 1023482 D 272621 CDS YP_193913.1 58337328 3252481 1024067..1024528 1 NC_006814.3 COG1959 Predicted transcriptional regulator; hypothetical protein 1024528 3252481 LBA1034 Lactobacillus acidophilus NCFM hypothetical protein YP_193913.1 1024067 D 272621 CDS YP_193914.1 58337329 3252486 complement(1024525..1024728) 1 NC_006814.3 transcriptional regulator; hypothetical protein 1024728 3252486 LBA1035 Lactobacillus acidophilus NCFM hypothetical protein YP_193914.1 1024525 R 272621 CDS YP_193915.1 58337330 3252490 1025436..1026806 1 NC_006814.3 branched-chain amino acid transporter 1026806 3252490 LBA1036 Lactobacillus acidophilus NCFM branched-chain amino acid transporter YP_193915.1 1025436 D 272621 CDS YP_193916.1 58337331 3252491 1026949..1027815 1 NC_006814.3 aldo-keto reductase; aldose reductase 1027815 3252491 LBA1037 Lactobacillus acidophilus NCFM aldose reductase YP_193916.1 1026949 D 272621 CDS YP_193917.1 58337332 3252497 complement(1028114..1029013) 1 NC_006814.3 cell surface protein precursor; hypothetical protein 1029013 3252497 LBA1038 Lactobacillus acidophilus NCFM hypothetical protein YP_193917.1 1028114 R 272621 CDS YP_193918.1 58337333 3252513 complement(1029495..1029788) 1 NC_006814.3 transcriptional regulator 1029788 lysR 3252513 lysR Lactobacillus acidophilus NCFM transcriptional regulator YP_193918.1 1029495 R 272621 CDS YP_193919.1 58337334 3252359 1029787..1029930 1 NC_006814.3 hydrolase 1029930 3252359 LBA1040 Lactobacillus acidophilus NCFM hydrolase YP_193919.1 1029787 D 272621 CDS YP_193920.1 58337335 3252531 1030269..1030928 1 NC_006814.3 glutamine ABC transporter membrane spanning permease 1030928 3252531 LBA1042 Lactobacillus acidophilus NCFM glutamine ABC transporter membrane spanning permease YP_193920.1 1030269 D 272621 CDS YP_193921.1 58337336 3252534 1030909..1031583 1 NC_006814.3 ABC transporter 1031583 3252534 LBA1044 Lactobacillus acidophilus NCFM ABC transporter YP_193921.1 1030909 D 272621 CDS YP_193922.1 58337337 3252529 1031592..1032332 1 NC_006814.3 glutamine ABC transporter ATP-binding protein 1032332 3252529 LBA1045 Lactobacillus acidophilus NCFM glutamine ABC transporter ATP-binding protein YP_193922.1 1031592 D 272621 CDS YP_193923.1 58337338 3252538 1032346..1033206 1 NC_006814.3 ATP-binding cassette transport system similar to substrate binding protein and to components of ABC transporter ORF J; glutamine ABC transporter substrate-binding protein 1033206 3252538 LBA1046 Lactobacillus acidophilus NCFM glutamine ABC transporter substrate-binding protein YP_193923.1 1032346 D 272621 CDS YP_193924.1 58337339 3252392 complement(1033490..1033984) 1 NC_006814.3 COG2077 Peroxiredoxin; thiol peroxidase Tpx 1033984 3252392 LBA1047 Lactobacillus acidophilus NCFM thiol peroxidase Tpx YP_193924.1 1033490 R 272621 CDS YP_193925.1 58337340 3252528 1034166..1034768 1 NC_006814.3 phosphoglycerate mutase 1034768 3252528 LBA1048 Lactobacillus acidophilus NCFM phosphoglycerate mutase YP_193925.1 1034166 D 272621 CDS YP_193926.1 58337341 3252565 1034781..1035695 1 NC_006814.3 4-oxalomesaconate hydratase 1035695 3252565 LBA1049 Lactobacillus acidophilus NCFM 4-oxalomesaconate hydratase YP_193926.1 1034781 D 272621 CDS YP_193927.1 58337342 3252569 complement(1036228..1036830) 1 NC_006814.3 hypothetical protein 1036830 3252569 LBA1050 Lactobacillus acidophilus NCFM hypothetical protein YP_193927.1 1036228 R 272621 CDS YP_193928.1 58337343 3252598 complement(1036850..1037464) 1 NC_006814.3 unknown hydrophobic protein; hydrophobic protein 1037464 3252598 LBA1051 Lactobacillus acidophilus NCFM hydrophobic protein YP_193928.1 1036850 R 272621 CDS YP_193929.1 58337344 3252566 1037523..1038191 1 NC_006814.3 glutamine amidotransferase 1038191 3252566 LBA1052 Lactobacillus acidophilus NCFM glutamine amidotransferase YP_193929.1 1037523 D 272621 CDS YP_193930.1 58337345 3252634 complement(1038259..1039452) 1 NC_006814.3 antibiotic resistance protein; membrane protein 1039452 3252634 LBA1053 Lactobacillus acidophilus NCFM membrane protein YP_193930.1 1038259 R 272621 CDS YP_193931.1 58337346 3252625 complement(1039552..1040388) 1 NC_006814.3 transcriptional regulator 1040388 lysR 3252625 lysR Lactobacillus acidophilus NCFM transcriptional regulator YP_193931.1 1039552 R 272621 CDS YP_193932.1 58337347 3252502 1040439..1041062 1 NC_006814.3 MutT; mutator protein 1041062 mutT 3252502 mutT Lactobacillus acidophilus NCFM mutator protein YP_193932.1 1040439 D 272621 CDS YP_193933.1 58337348 3252666 complement(1041197..1041652) 1 NC_006814.3 cation efflux system (zinc-cadmium); hypothetical protein 1041652 3252666 LBA1056 Lactobacillus acidophilus NCFM hypothetical protein YP_193933.1 1041197 R 272621 CDS YP_193934.1 58337349 3252663 1041828..1042295 1 NC_006814.3 HIT-like protein 1042295 3252663 LBA1057 Lactobacillus acidophilus NCFM HIT-like protein YP_193934.1 1041828 D 272621 CDS YP_193935.1 58337350 3252681 1042316..1042675 1 NC_006814.3 hypothetical protein 1042675 3252681 LBA1058 Lactobacillus acidophilus NCFM hypothetical protein YP_193935.1 1042316 D 272621 CDS YP_193936.1 58337351 3252684 1042681..1043196 1 NC_006814.3 ribosomal-protein-serine N-acetyltransferase 1043196 3252684 LBA1059 Lactobacillus acidophilus NCFM ribosomal-protein-serine N-acetyltransferase YP_193936.1 1042681 D 272621 CDS YP_193938.1 58337353 3252589 1044025..1044621 1 NC_006814.3 phosphate transporter related protein 1044621 3252589 LBA1061 Lactobacillus acidophilus NCFM phosphate transporter related protein YP_193938.1 1044025 D 272621 CDS YP_193939.1 58337354 3252723 1044704..1045225 1 NC_006814.3 multidrug efflux permease 1045225 3252723 LBA1062 Lactobacillus acidophilus NCFM multidrug efflux permease YP_193939.1 1044704 D 272621 CDS YP_193940.1 58337355 3252611 1045370..1045573 1 NC_006814.3 hypothetical protein 1045573 3252611 LBA1063 Lactobacillus acidophilus NCFM hypothetical protein YP_193940.1 1045370 D 272621 CDS YP_193941.1 58337356 3252604 1045679..1046440 1 NC_006814.3 COG2820 Uridine phosphorylase; phosphorylase 1046440 3252604 LBA1064 Lactobacillus acidophilus NCFM phosphorylase YP_193941.1 1045679 D 272621 CDS YP_193942.1 58337357 3252711 1046468..1047064 1 NC_006814.3 Phosphoglycerate mutase; phosphoglycerate mutase 1047064 3252711 LBA1065 Lactobacillus acidophilus NCFM phosphoglycerate mutase YP_193942.1 1046468 D 272621 CDS YP_193943.1 58337358 3252745 1047092..1047862 1 NC_006814.3 COG2820 Uridine phosphorylase; phosphorylase 1047862 3252745 LBA1066 Lactobacillus acidophilus NCFM phosphorylase YP_193943.1 1047092 D 272621 CDS YP_193944.1 58337359 3252746 1047879..1048640 1 NC_006814.3 COG2820 Uridine phosphorylase; phosphorylase 1048640 3252746 LBA1067 Lactobacillus acidophilus NCFM phosphorylase YP_193944.1 1047879 D 272621 CDS YP_193945.1 58337360 3252789 1048680..1049282 1 NC_006814.3 HAD superfamily hydrolase 1049282 3252789 LBA1068 Lactobacillus acidophilus NCFM HAD superfamily hydrolase YP_193945.1 1048680 D 272621 CDS YP_193946.1 58337361 3252799 1049388..1049495 1 NC_006814.3 hypothetical protein 1049495 3252799 LBA1069 Lactobacillus acidophilus NCFM hypothetical protein YP_193946.1 1049388 D 272621 CDS YP_193947.1 58337362 3252841 complement(1049615..1049848) 1 NC_006814.3 hypothetical protein 1049848 3252841 LBA1070 Lactobacillus acidophilus NCFM hypothetical protein YP_193947.1 1049615 R 272621 CDS YP_008992038.1 568886572 18111640 1050230..1050619 1 NC_006814.3 malate transporter; hypothetical protein 1050619 18111640 LBA1070b Lactobacillus acidophilus NCFM hypothetical protein YP_008992038.1 1050230 D 272621 CDS YP_193948.1 58337363 3252837 1051871..1052524 1 NC_006814.3 hypothetical protein 1052524 3252837 LBA1071 Lactobacillus acidophilus NCFM hypothetical protein YP_193948.1 1051871 D 272621 CDS YP_193949.1 58337364 3252889 1052545..1052790 1 NC_006814.3 hypothetical protein 1052790 3252889 LBA1072 Lactobacillus acidophilus NCFM hypothetical protein YP_193949.1 1052545 D 272621 CDS YP_193950.1 58337365 3252883 complement(1053480..1054394) 1 NC_006814.3 malolactic regulator 1054394 lysR 3252883 lysR Lactobacillus acidophilus NCFM malolactic regulator YP_193950.1 1053480 R 272621 CDS YP_193951.1 58337366 3252907 1054523..1056148 1 NC_006814.3 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase 1056148 3252907 LBA1075 Lactobacillus acidophilus NCFM malate dehydrogenase YP_193951.1 1054523 D 272621 CDS YP_193952.1 58337367 3252910 complement(1056215..1056802) 1 NC_006814.3 COG4292 Predicted membrane protein; hypothetical protein 1056802 ltrA 3252910 ltrA Lactobacillus acidophilus NCFM hypothetical protein YP_193952.1 1056215 R 272621 CDS YP_193953.1 58337368 3252923 1056906..1058195 1 NC_006814.3 recombination factor protein RarA 1058195 3252923 LBA1077 Lactobacillus acidophilus NCFM recombination factor protein RarA YP_193953.1 1056906 D 272621 CDS YP_193954.1 58337369 3252955 1058279..1059256 1 NC_006814.3 bile salt hydrolase 1059256 bshB 3252955 bshB Lactobacillus acidophilus NCFM bile salt hydrolase YP_193954.1 1058279 D 272621 CDS YP_193955.1 58337370 3252972 1059602..1060210 1 NC_006814.3 cell surface protein 1060210 3252972 LBA1079 Lactobacillus acidophilus NCFM cell surface protein YP_193955.1 1059602 D 272621 CDS YP_193956.1 58337371 3252988 1060637..1061755 1 NC_006814.3 MetE; methionine synthase 1061755 metK 3252988 metK Lactobacillus acidophilus NCFM methionine synthase YP_193956.1 1060637 D 272621 CDS YP_193957.1 58337372 3253048 1061945..1062418 1 NC_006814.3 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 1062418 luxS 3253048 luxS Lactobacillus acidophilus NCFM S-ribosylhomocysteinase YP_193957.1 1061945 D 272621 CDS YP_193958.1 58337373 3253073 1062581..1063261 1 NC_006814.3 hypothetical protein 1063261 3253073 LBA1082 Lactobacillus acidophilus NCFM hypothetical protein YP_193958.1 1062581 D 272621 CDS YP_193959.1 58337374 3252826 1063261..1064106 1 NC_006814.3 membrane nuclease 1064106 3252826 LBA1083 Lactobacillus acidophilus NCFM membrane nuclease YP_193959.1 1063261 D 272621 CDS YP_193960.1 58337375 3252823 1064205..1064849 1 NC_006814.3 COG2910 NADH-flavin reductase; NADH-flavin reductase 1064849 3252823 LBA1084 Lactobacillus acidophilus NCFM NADH-flavin reductase YP_193960.1 1064205 D 272621 CDS YP_193961.1 58337376 3253074 complement(1064914..1066239) 1 NC_006814.3 amino acid transport protein; amino acid permease 1066239 3253074 LBA1086 Lactobacillus acidophilus NCFM amino acid permease YP_193961.1 1064914 R 272621 CDS YP_193962.1 58337377 3253075 1066779..1067366 1 NC_006814.3 potential frameshift to 1088; cysteine synthase 1067366 3253075 LBA1087 Lactobacillus acidophilus NCFM cysteine synthase YP_193962.1 1066779 D 272621 CDS YP_193963.1 58337378 3253084 1067600..1067710 1 NC_006814.3 potential frameshift to 1087; COG0031 Cysteine synthase; cysteine synthase 1067710 3253084 LBA1088 Lactobacillus acidophilus NCFM cysteine synthase YP_193963.1 1067600 D 272621 CDS YP_193964.1 58337379 3253089 1067892..1068149 1 NC_006814.3 potential frameshift to 1090; cystathionine beta-lyase 1068149 3253089 LBA1089 Lactobacillus acidophilus NCFM cystathionine beta-lyase YP_193964.1 1067892 D 272621 CDS YP_193965.1 58337380 3253077 1068231..1069037 1 NC_006814.3 potential frameshift to 1089; MetC; cystathionine beta-lyase 1069037 metC 3253077 metC Lactobacillus acidophilus NCFM cystathionine beta-lyase YP_193965.1 1068231 D 272621 CDS YP_193966.1 58337381 3253108 1069236..1069463 1 NC_006814.3 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 1069463 luxS 3253108 luxS Lactobacillus acidophilus NCFM S-ribosylhomocysteinase YP_193966.1 1069236 D 272621 CDS YP_193967.1 58337382 3253079 complement(1069606..1072344) 1 NC_006814.3 catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 1072344 3253079 LBA1092 Lactobacillus acidophilus NCFM phosphoenolpyruvate carboxylase YP_193967.1 1069606 R 272621 CDS YP_193968.1 58337383 3252874 1072591..1076307 1 NC_006814.3 conserved hypothetical protein; helicase 1076307 3252874 LBA1093 Lactobacillus acidophilus NCFM helicase YP_193968.1 1072591 D 272621 CDS YP_193969.1 58337384 3253017 1076307..1078367 1 NC_006814.3 ATPase 1078367 3253017 LBA1094 Lactobacillus acidophilus NCFM ATPase YP_193969.1 1076307 D 272621 CDS YP_193970.1 58337385 3252126 1078370..1078528 1 NC_006814.3 phosphotransferase 1078528 3252126 LBA1095 Lactobacillus acidophilus NCFM phosphotransferase YP_193970.1 1078370 D 272621 CDS YP_193971.1 58337386 3252927 complement(1078674..1079603) 1 NC_006814.3 COG2378 Predicted transcriptional regulator; repressor protein 1079603 3252927 LBA1096 Lactobacillus acidophilus NCFM repressor protein YP_193971.1 1078674 R 272621 CDS YP_193972.1 58337387 3252134 1079691..1080149 1 NC_006814.3 hypothetical protein 1080149 3252134 LBA1097 Lactobacillus acidophilus NCFM hypothetical protein YP_193972.1 1079691 D 272621 CDS YP_193973.1 58337388 3252319 1080285..1081073 1 NC_006814.3 Converts glucose to D-glucono-1,5 lactone; glucose-1-dehydrogenase 1081073 3252319 LBA1098 Lactobacillus acidophilus NCFM glucose-1-dehydrogenase YP_193973.1 1080285 D 272621 CDS YP_193974.1 58337389 3252928 complement(1081344..1081655) 1 NC_006814.3 phosphinothricin N-acetyltransferase 1081655 3252928 LBA1099 Lactobacillus acidophilus NCFM phosphinothricin N-acetyltransferase YP_193974.1 1081344 R 272621 CDS YP_193975.1 58337390 3252311 1081847..1082470 1 NC_006814.3 potential frameshift to 1101; aldo/keto reductase 1082470 3252311 LBA1100 Lactobacillus acidophilus NCFM aldo/keto reductase YP_193975.1 1081847 D 272621 CDS YP_193976.1 58337391 3252476 1082486..1082845 1 NC_006814.3 potential frameshift to 1100; oxidoreductase 1082845 3252476 LBA1101 Lactobacillus acidophilus NCFM oxidoreductase YP_193976.1 1082486 D 272621 CDS YP_193977.1 58337392 3252478 1083164..1084006 1 NC_006814.3 transmembrane protein 1084006 3252478 LBA1102 Lactobacillus acidophilus NCFM transmembrane protein YP_193977.1 1083164 D 272621 CDS YP_193978.1 58337393 3252507 1084245..1084520 1 NC_006814.3 potential frameshift to 1105; Flavodoxin; flavodoxin 1084520 3252507 LBA1103 Lactobacillus acidophilus NCFM flavodoxin YP_193978.1 1084245 D 272621 CDS YP_193979.1 58337394 3252729 1084547..1084645 1 NC_006814.3 hypothetical protein 1084645 3252729 LBA1104 Lactobacillus acidophilus NCFM hypothetical protein YP_193979.1 1084547 D 272621 CDS YP_193980.1 58337395 3252782 1084690..1085301 1 NC_006814.3 potential frameshift to 1103; COG0716 Flavodoxins; flavodoxin 1085301 3252782 LBA1105 Lactobacillus acidophilus NCFM flavodoxin YP_193980.1 1084690 D 272621 CDS YP_193981.1 58337396 3252200 1085327..1085890 1 NC_006814.3 COG3693 Beta-1,4-xylanase; hypothetical protein 1085890 3252200 LBA1106 Lactobacillus acidophilus NCFM hypothetical protein YP_193981.1 1085327 D 272621 CDS YP_193982.1 58337397 3252805 1086025..1087356 1 NC_006814.3 COG1249 Pyruvate-2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component; glutathione reductase 1087356 3252805 LBA1107 Lactobacillus acidophilus NCFM glutathione reductase YP_193982.1 1086025 D 272621 CDS YP_193983.1 58337398 3252400 1087523..1087702 1 NC_006814.3 hypothetical protein 1087702 3252400 LBA1108 Lactobacillus acidophilus NCFM hypothetical protein YP_193983.1 1087523 D 272621 CDS YP_193984.1 58337399 3252863 1087895..1088659 1 NC_006814.3 flavodoxin; hypothetical protein 1088659 3252863 LBA1109 Lactobacillus acidophilus NCFM hypothetical protein YP_193984.1 1087895 D 272621 CDS YP_193985.1 58337400 3252495 1088788..1089342 1 NC_006814.3 hypothetical protein 1089342 3252495 LBA1110 Lactobacillus acidophilus NCFM hypothetical protein YP_193985.1 1088788 D 272621 CDS YP_193986.1 58337401 3253028 1089457..1089804 1 NC_006814.3 potential frameshift to 1112; COG0716 Flavodoxins; flavodoxin 1089804 3253028 LBA1111 Lactobacillus acidophilus NCFM flavodoxin YP_193986.1 1089457 D 272621 CDS YP_193987.1 58337402 3252931 1089741..1089959 1 NC_006814.3 potential frameshift to 1111; flavodoxin 1089959 3252931 LBA1112 Lactobacillus acidophilus NCFM flavodoxin YP_193987.1 1089741 D 272621 CDS YP_193988.1 58337403 3252307 1089959..1090774 1 NC_006814.3 potential frameshift to 1114; ferric reductase 1090774 3252307 LBA1113 Lactobacillus acidophilus NCFM ferric reductase YP_193988.1 1089959 D 272621 CDS YP_193989.1 58337404 3252844 1090774..1091223 1 NC_006814.3 potential frameshift to 1113; alcohol dehydrogenase, zinc-containing; alcohol dehydrogenase 1091223 3252844 LBA1114 Lactobacillus acidophilus NCFM alcohol dehydrogenase YP_193989.1 1090774 D 272621 CDS YP_193990.1 58337405 3252381 1091686..1093056 1 NC_006814.3 COG0531 Amino acid transporters; amino acid permease 1093056 3252381 LBA1115 Lactobacillus acidophilus NCFM amino acid permease YP_193990.1 1091686 D 272621 CDS YP_193991.1 58337406 3252938 complement(1093461..1093736) 1 NC_006814.3 potential frameshift to 1117; pyrroline-5-carboxylate reductase 1093736 3252938 LBA1116 Lactobacillus acidophilus NCFM pyrroline-5-carboxylate reductase YP_193991.1 1093461 R 272621 CDS YP_193992.1 58337407 3252695 complement(1093723..1094010) 1 NC_006814.3 potential frameshift to 1116; pyrroline reductase 1094010 3252695 LBA1117 Lactobacillus acidophilus NCFM pyrroline reductase YP_193992.1 1093723 R 272621 CDS YP_193993.1 58337408 3252560 complement(1094257..1094481) 1 NC_006814.3 hypothetical protein 1094481 3252560 LBA1118 Lactobacillus acidophilus NCFM hypothetical protein YP_193993.1 1094257 R 272621 CDS YP_193994.1 58337409 3252206 1094914..1095900 1 NC_006814.3 COG2855 Predicted membrane protein; hypothetical protein 1095900 3252206 LBA1119 Lactobacillus acidophilus NCFM hypothetical protein YP_193994.1 1094914 D 272621 CDS YP_193995.1 58337410 3252197 complement(1096118..1096687) 1 NC_006814.3 UDP-glycosyltransferase 37b1 CG9481-PA; hypothetical protein 1096687 3252197 LBA1120 Lactobacillus acidophilus NCFM hypothetical protein YP_193995.1 1096118 R 272621 CDS YP_193996.1 58337411 3252196 complement(1096921..1097556) 1 NC_006814.3 COG0344 Predicted membrane protein; hypothetical protein 1097556 3252196 LBA1121 Lactobacillus acidophilus NCFM hypothetical protein YP_193996.1 1096921 R 272621 CDS YP_193997.1 58337412 3252374 1097653..1099599 1 NC_006814.3 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 1099599 3252374 LBA1122 Lactobacillus acidophilus NCFM DNA topoisomerase IV subunit B YP_193997.1 1097653 D 272621 CDS YP_193998.1 58337413 3252652 1099628..1102078 1 NC_006814.3 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 1102078 3252652 LBA1123 Lactobacillus acidophilus NCFM DNA topoisomerase IV subunit A YP_193998.1 1099628 D 272621 CDS YP_193999.1 58337414 3252736 1102215..1103186 1 NC_006814.3 transcriptional regulator 1103186 lysR 3252736 lysR Lactobacillus acidophilus NCFM transcriptional regulator YP_193999.1 1102215 D 272621 CDS YP_194000.1 58337415 3252945 1103207..1104142 1 NC_006814.3 catalyzes the hydrolysis of pyrophosphate to phosphate; manganese-dependent inorganic pyrophosphatase 1104142 3252945 LBA1125 Lactobacillus acidophilus NCFM manganese-dependent inorganic pyrophosphatase YP_194000.1 1103207 D 272621 CDS YP_194001.1 58337416 3252714 1104280..1104879 1 NC_006814.3 peptidyl-prolyl cis-trans isomerase 1104879 3252714 LBA1126 Lactobacillus acidophilus NCFM peptidyl-prolyl cis-trans isomerase YP_194001.1 1104280 D 272621 CDS YP_194003.1 58337418 3252956 1105576..1106295 1 NC_006814.3 COG3619 Predicted membrane protein; hypothetical protein 1106295 3252956 LBA1128 Lactobacillus acidophilus NCFM hypothetical protein YP_194003.1 1105576 D 272621 CDS YP_194004.1 58337419 3252372 complement(1107612..1107986) 1 NC_006814.3 cell division protein 1107986 3252372 LBA1129 Lactobacillus acidophilus NCFM cell division protein YP_194004.1 1107612 R 272621 CDS YP_194005.1 58337420 3252019 complement(1108657..1110240) 1 NC_006814.3 ABC transporter ATP-binding protein/permease 1110240 3252019 LBA1131 Lactobacillus acidophilus NCFM ABC transporter ATP-binding protein/permease YP_194005.1 1108657 R 272621 CDS YP_194006.1 58337421 3252442 complement(1110237..1111826) 1 NC_006814.3 lactococcin A ABC transporter ATP binding protein 1111826 3252442 LBA1132 Lactobacillus acidophilus NCFM lactococcin A ABC transporter ATP binding protein YP_194006.1 1110237 R 272621 CDS YP_194007.1 58337422 3252583 1112206..1113423 1 NC_006814.3 Macrolide-efflux protein; macrolide efflux protein 1113423 3252583 LBA1135 Lactobacillus acidophilus NCFM macrolide efflux protein YP_194007.1 1112206 D 272621 CDS YP_194008.1 58337423 3252250 complement(1113652..1114158) 1 NC_006814.3 transcriptional regulator 1114158 3252250 LBA1136 Lactobacillus acidophilus NCFM transcriptional regulator YP_194008.1 1113652 R 272621 CDS YP_194009.1 58337424 3252418 complement(1114189..1114527) 1 NC_006814.3 ACP phosphodieterase 1114527 acpD 3252418 acpD Lactobacillus acidophilus NCFM ACP phosphodieterase YP_194009.1 1114189 R 272621 CDS YP_194010.1 58337425 3252403 complement(1114553..1114645) 1 NC_006814.3 acyl carrier protein phosphodiesterase; hypothetical protein 1114645 3252403 LBA1138 Lactobacillus acidophilus NCFM hypothetical protein YP_194010.1 1114553 R 272621 CDS YP_194011.1 58337426 3252986 1115108..1116256 1 NC_006814.3 COG3757 Lyzozyme M1 (1,4-beta-N-acetylmuramidase); lysin 1116256 3252986 LBA1140 Lactobacillus acidophilus NCFM lysin YP_194011.1 1115108 D 272621 CDS YP_194012.1 58337427 3252673 1116352..1116960 1 NC_006814.3 membrane protein; diaphanous-like protein 1116960 3252673 LBA1142 Lactobacillus acidophilus NCFM diaphanous-like protein YP_194012.1 1116352 D 272621 CDS YP_194013.1 58337428 3252594 complement(1116997..1117488) 1 NC_006814.3 FlaR; adenylate kinase 1117488 flaR 3252594 flaR Lactobacillus acidophilus NCFM adenylate kinase YP_194013.1 1116997 R 272621 CDS YP_194014.1 58337429 3252690 complement(1117490..1117939) 1 NC_006814.3 harderin; hypothetical protein 1117939 3252690 LBA1144 Lactobacillus acidophilus NCFM hypothetical protein YP_194014.1 1117490 R 272621 CDS YP_194015.1 58337430 3252440 1118473..1119501 1 NC_006814.3 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerS; site-specific tyrosine recombinase XerS 1119501 xerS 3252440 xerS Lactobacillus acidophilus NCFM site-specific tyrosine recombinase XerS YP_194015.1 1118473 D 272621 CDS YP_194016.1 58337431 3252129 complement(1119559..1120440) 1 NC_006814.3 DegV; family protein 1120440 3252129 LBA1146 Lactobacillus acidophilus NCFM family protein YP_194016.1 1119559 R 272621 CDS YP_194017.1 58337432 3252353 complement(1120518..1120928) 1 NC_006814.3 l-fucose operon 1120928 3252353 LBA1147 Lactobacillus acidophilus NCFM l-fucose operon YP_194017.1 1120518 R 272621 CDS YP_194018.1 58337433 3252354 1121171..1122862 1 NC_006814.3 fibronectin-binding protein 1122862 3252354 LBA1148 Lactobacillus acidophilus NCFM fibronectin-binding protein YP_194018.1 1121171 D 272621 CDS YP_194019.1 58337434 3252942 complement(1122934..1126119) 1 NC_006814.3 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 1126119 carB 3252942 carB Lactobacillus acidophilus NCFM carbamoyl phosphate synthase large subunit YP_194019.1 1122934 R 272621 CDS YP_194020.1 58337435 3252378 complement(1126123..1127178) 1 NC_006814.3 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 1127178 3252378 LBA1150 Lactobacillus acidophilus NCFM carbamoyl phosphate synthase small subunit YP_194020.1 1126123 R 272621 CDS YP_194021.1 58337436 3252496 complement(1127183..1128091) 1 NC_006814.3 pseudouridine synthase 1128091 3252496 LBA1151 Lactobacillus acidophilus NCFM pseudouridine synthase YP_194021.1 1127183 R 272621 CDS YP_194022.1 58337437 3252195 complement(1128084..1128587) 1 NC_006814.3 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 1128587 lspA 3252195 lspA Lactobacillus acidophilus NCFM lipoprotein signal peptidase YP_194022.1 1128084 R 272621 CDS YP_194023.1 58337438 3252922 complement(1128559..1130235) 1 NC_006814.3 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase 1130235 purU 3252922 purU Lactobacillus acidophilus NCFM formate--tetrahydrofolate ligase YP_194023.1 1128559 R 272621 CDS YP_194024.1 58337439 3253088 complement(1130733..1131965) 1 NC_006814.3 CpdA; COG1409 Predicted phosphohydrolases; 3',5'-cyclic-nucleotide phosphodiesterase 1131965 cpdA 3253088 cpdA Lactobacillus acidophilus NCFM 3',5'-cyclic-nucleotide phosphodiesterase YP_194024.1 1130733 R 272621 CDS YP_194025.1 58337440 3253083 complement(1131968..1133092) 1 NC_006814.3 hypothetical protein 1133092 3253083 LBA1155 Lactobacillus acidophilus NCFM hypothetical protein YP_194025.1 1131968 R 272621 CDS YP_194026.1 58337441 3253076 complement(1133557..1133970) 1 NC_006814.3 hypothetical protein 1133970 3253076 LBA1156 Lactobacillus acidophilus NCFM hypothetical protein YP_194026.1 1133557 R 272621 CDS YP_194027.1 58337442 3253094 complement(1134066..1134629) 1 NC_006814.3 hypothetical protein 1134629 3253094 LBA1157 Lactobacillus acidophilus NCFM hypothetical protein YP_194027.1 1134066 R 272621 CDS YP_194028.1 58337443 3253087 1134698..1135333 1 NC_006814.3 functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC; Holliday junction-specific endonuclease 1135333 recU 3253087 recU Lactobacillus acidophilus NCFM Holliday junction-specific endonuclease YP_194028.1 1134698 D 272621 CDS YP_194029.1 58337444 3253082 1135333..1137663 1 NC_006814.3 Pbp1; penicillin binding protein 1A 1137663 3253082 LBA1159 Lactobacillus acidophilus NCFM penicillin binding protein 1A YP_194029.1 1135333 D 272621 CDS YP_194030.1 58337445 3253093 complement(1137842..1138471) 1 NC_006814.3 End3; COG0177 Predicted EndoIII-related endonuclease; endonuclease III 1138471 3253093 LBA1160 Lactobacillus acidophilus NCFM endonuclease III YP_194030.1 1137842 R 272621 CDS YP_194031.1 58337446 3253061 complement(1138473..1139117) 1 NC_006814.3 DnaD; initiation of chromosome replication protein 1139117 dnaD 3253061 dnaD Lactobacillus acidophilus NCFM initiation of chromosome replication protein YP_194031.1 1138473 R 272621 CDS YP_194032.1 58337447 3253101 complement(1139255..1140499) 1 NC_006814.3 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 1140499 asnC 3253101 asnC Lactobacillus acidophilus NCFM asparaginyl-tRNA synthetase YP_194032.1 1139255 R 272621 CDS YP_194033.1 58337448 3253103 complement(1140554..1141051) 1 NC_006814.3 hypothetical protein 1141051 3253103 LBA1163 Lactobacillus acidophilus NCFM hypothetical protein YP_194033.1 1140554 R 272621 CDS YP_194034.1 58337449 3253070 complement(1141054..1143837) 1 NC_006814.3 DinG; ATP-dependent DNA helicase 1143837 dinG 3253070 dinG Lactobacillus acidophilus NCFM ATP-dependent DNA helicase YP_194034.1 1141054 R 272621 CDS YP_194035.1 58337450 3253086 complement(1143861..1147484) 1 NC_006814.3 AddA; COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); ATP-dependent exonuclease subunit A 1147484 addA 3253086 addA Lactobacillus acidophilus NCFM ATP-dependent exonuclease subunit A YP_194035.1 1143861 R 272621 CDS YP_194036.1 58337451 3253068 complement(1147487..1150969) 1 NC_006814.3 AddB; ATP-dependent exonuclease subunit B 1150969 addB 3253068 addB Lactobacillus acidophilus NCFM ATP-dependent exonuclease subunit B YP_194036.1 1147487 R 272621 CDS YP_194037.1 58337452 3253078 1151051..1151959 1 NC_006814.3 mevalonate kinase 1151959 mvaK 3253078 mvaK Lactobacillus acidophilus NCFM mevalonate kinase YP_194037.1 1151051 D 272621 CDS YP_194038.1 58337453 3253057 1151965..1152927 1 NC_006814.3 mevalonate diphosphate decarboxylase 1152927 mvaD 3253057 mvaD Lactobacillus acidophilus NCFM mevalonate diphosphate decarboxylase YP_194038.1 1151965 D 272621 CDS YP_194039.1 58337454 3253097 1152971..1154053 1 NC_006814.3 phosphomevalonate kinase 1154053 3253097 LBA1169 Lactobacillus acidophilus NCFM phosphomevalonate kinase YP_194039.1 1152971 D 272621 CDS YP_194040.1 58337455 3253102 1154066..1155085 1 NC_006814.3 catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate; isopentenyl pyrophosphate isomerase 1155085 3253102 LBA1171 Lactobacillus acidophilus NCFM isopentenyl pyrophosphate isomerase YP_194040.1 1154066 D 272621 CDS YP_194041.1 58337456 3253067 complement(1155137..1155976) 1 NC_006814.3 COG1737 transcriptional regulators; transcriptional regulator 1155976 3253067 LBA1172 Lactobacillus acidophilus NCFM transcriptional regulator YP_194041.1 1155137 R 272621 CDS YP_194042.1 58337457 3253085 1156105..1156287 1 NC_006814.3 hypothetical protein 1156287 3253085 LBA1173 Lactobacillus acidophilus NCFM hypothetical protein YP_194042.1 1156105 D 272621 CDS YP_194043.1 58337458 3253060 1156265..1156735 1 NC_006814.3 ribose 5-phosphate 1156735 3253060 LBA1174 Lactobacillus acidophilus NCFM ribose 5-phosphate YP_194043.1 1156265 D 272621 CDS YP_194044.1 58337459 3253099 1156797..1157372 1 NC_006814.3 potential frameshift to 1176; dehydrogenase 1157372 3253099 LBA1175 Lactobacillus acidophilus NCFM dehydrogenase YP_194044.1 1156797 D 272621 CDS YP_194045.1 58337460 3253072 1157429..1157776 1 NC_006814.3 potential frameshift to 1175; dehydrogenase 1157776 3253072 LBA1176 Lactobacillus acidophilus NCFM dehydrogenase YP_194045.1 1157429 D 272621 CDS YP_194046.1 58337461 3253106 complement(1157833..1158984) 1 NC_006814.3 YrvO; cysteine desulfurase; iron-sulfur cofactor synthesis protein 1158984 3253106 LBA1177 Lactobacillus acidophilus NCFM iron-sulfur cofactor synthesis protein YP_194046.1 1157833 R 272621 CDS YP_194047.1 58337462 3253110 complement(1159102..1160487) 1 NC_006814.3 hypothetical protein 1160487 3253110 LBA1178 Lactobacillus acidophilus NCFM hypothetical protein YP_194047.1 1159102 R 272621 CDS YP_194048.1 58337463 3253059 complement(1160468..1161445) 1 NC_006814.3 hypothetical protein 1161445 3253059 LBA1180 Lactobacillus acidophilus NCFM hypothetical protein YP_194048.1 1160468 R 272621 CDS YP_194049.1 58337464 3253100 complement(1161435..1162187) 1 NC_006814.3 hypothetical protein 1162187 3253100 LBA1181 Lactobacillus acidophilus NCFM hypothetical protein YP_194049.1 1161435 R 272621 CDS YP_194050.1 58337465 3252114 1162274..1162516 1 NC_006814.3 COG0681 Signal peptidase I; signal peptidase 1162516 3252114 LBA1182 Lactobacillus acidophilus NCFM signal peptidase YP_194050.1 1162274 D 272621 CDS YP_194051.1 58337466 3253105 1162917..1163105 1 NC_006814.3 hypothetical protein 1163105 3253105 LBA1183 Lactobacillus acidophilus NCFM hypothetical protein YP_194051.1 1162917 D 272621 CDS YP_194052.1 58337467 3252176 complement(1163164..1163940) 1 NC_006814.3 hypothetical protein 1163940 3252176 LBA1184 Lactobacillus acidophilus NCFM hypothetical protein YP_194052.1 1163164 R 272621 CDS YP_194053.1 58337468 3252153 complement(1163959..1164792) 1 NC_006814.3 hypothetical protein 1164792 3252153 LBA1186 Lactobacillus acidophilus NCFM hypothetical protein YP_194053.1 1163959 R 272621 CDS YP_194054.1 58337469 3252047 complement(1164811..1165641) 1 NC_006814.3 hypothetical protein 1165641 3252047 LBA1187 Lactobacillus acidophilus NCFM hypothetical protein YP_194054.1 1164811 R 272621 CDS YP_194055.1 58337470 3252050 complement(1165641..1166348) 1 NC_006814.3 ABC transporter ATP-binding protein 1166348 3252050 LBA1188 Lactobacillus acidophilus NCFM ABC transporter ATP-binding protein YP_194055.1 1165641 R 272621 CDS YP_194056.1 58337471 3252075 complement(1166341..1166715) 1 NC_006814.3 GntR; transcriptional regulator 1166715 gntR 3252075 gntR Lactobacillus acidophilus NCFM transcriptional regulator YP_194056.1 1166341 R 272621 CDS YP_194057.1 58337472 3252073 complement(1167013..1168260) 1 NC_006814.3 catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 1168260 pepT 3252073 pepT Lactobacillus acidophilus NCFM peptidase T YP_194057.1 1167013 R 272621 CDS YP_194058.1 58337473 3252107 complement(1168287..1169084) 1 NC_006814.3 hypothetical protein 1169084 3252107 LBA1191 Lactobacillus acidophilus NCFM hypothetical protein YP_194058.1 1168287 R 272621 CDS YP_194059.1 58337474 3252112 complement(1169077..1169763) 1 NC_006814.3 COG2384 Predicted SAM-dependent methyltransferase; methyltransferase 1169763 3252112 LBA1192 Lactobacillus acidophilus NCFM methyltransferase YP_194059.1 1169077 R 272621 CDS YP_194060.1 58337475 3252086 1169862..1170302 1 NC_006814.3 MutT; mutator protein 1170302 mutT 3252086 mutT Lactobacillus acidophilus NCFM mutator protein YP_194060.1 1169862 D 272621 CDS YP_194061.1 58337476 3252103 1170302..1170967 1 NC_006814.3 potential frameshift to 1195; enterolysin A 1170967 3252103 LBA1194 Lactobacillus acidophilus NCFM enterolysin A YP_194061.1 1170302 D 272621 CDS YP_194062.1 58337477 3251542 1170939..1171031 1 NC_006814.3 potential frameshift to 1194; hypothetical protein; enterolysin A 1171031 3251542 LBA1195 Lactobacillus acidophilus NCFM enterolysin A YP_194062.1 1170939 D 272621 CDS YP_194063.1 58337478 3252069 complement(1171021..1172091) 1 NC_006814.3 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium; RNA polymerase sigma factor RpoD 1172091 rpoD 3252069 rpoD Lactobacillus acidophilus NCFM RNA polymerase sigma factor RpoD YP_194063.1 1171021 R 272621 CDS YP_194064.1 58337479 3251181 complement(1172133..1173983) 1 NC_006814.3 DNA primase 1173983 3251181 LBA1197 Lactobacillus acidophilus NCFM DNA primase YP_194064.1 1172133 R 272621 CDS YP_194065.1 58337480 3252088 complement(1174006..1176069) 1 NC_006814.3 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 1176069 glyS 3252088 glyS Lactobacillus acidophilus NCFM glycyl-tRNA synthetase subunit beta YP_194065.1 1174006 R 272621 CDS YP_194066.1 58337481 3252087 complement(1176062..1176979) 1 NC_006814.3 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 1176979 glyQ 3252087 glyQ Lactobacillus acidophilus NCFM glycyl-tRNA synthetase subunit alpha YP_194066.1 1176062 R 272621 CDS YP_194067.1 58337482 3251182 complement(1177238..1177990) 1 NC_006814.3 RecO; DNA repair protein 1177990 recO 3251182 recO Lactobacillus acidophilus NCFM DNA repair protein YP_194067.1 1177238 R 272621 CDS YP_194068.1 58337483 3251203 complement(1178087..1178992) 1 NC_006814.3 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 1178992 era 3251203 era Lactobacillus acidophilus NCFM GTP-binding protein Era YP_194068.1 1178087 R 272621 CDS YP_194069.1 58337484 3252070 complement(1178994..1179518) 1 NC_006814.3 COG0319 Predicted metal-dependent hydrolase; hypothetical protein 1179518 3252070 LBA1202 Lactobacillus acidophilus NCFM hypothetical protein YP_194069.1 1178994 R 272621 CDS YP_194070.1 58337485 3252058 complement(1179521..1180480) 1 NC_006814.3 PhoH; PhoH family phosphate starvation-induced protein 1180480 phoH 3252058 phoH Lactobacillus acidophilus NCFM PhoH family phosphate starvation-induced protein YP_194070.1 1179521 R 272621 CDS YP_194071.1 58337486 3252064 complement(1180505..1180948) 1 NC_006814.3 hypothetical protein 1180948 3252064 LBA1204 Lactobacillus acidophilus NCFM hypothetical protein YP_194071.1 1180505 R 272621 CDS YP_194072.1 58337487 3252115 complement(1181214..1181390) 1 NC_006814.3 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 1181390 rpsU 3252115 rpsU Lactobacillus acidophilus NCFM 30S ribosomal protein S21 YP_194072.1 1181214 R 272621 CDS YP_194073.1 58337488 3252066 1181656..1182492 1 NC_006814.3 hypothetical protein 1182492 3252066 LBA1206 Lactobacillus acidophilus NCFM hypothetical protein YP_194073.1 1181656 D 272621 CDS YP_194074.1 58337489 3252094 1182662..1183303 1 NC_006814.3 enterolysin A 1183303 3252094 LBA1207 Lactobacillus acidophilus NCFM enterolysin A YP_194074.1 1182662 D 272621 CDS YP_194075.1 58337490 3252084 1183428..1183997 1 NC_006814.3 MsrA; peptide methionine sulfoxide reductase 1183997 msrA 3252084 msrA Lactobacillus acidophilus NCFM peptide methionine sulfoxide reductase YP_194075.1 1183428 D 272621 CDS YP_194076.1 58337491 3252105 1184082..1184960 1 NC_006814.3 COG1284 Uncharacterized conserved protein; hypothetical protein 1184960 3252105 LBA1209 Lactobacillus acidophilus NCFM hypothetical protein YP_194076.1 1184082 D 272621 CDS YP_194077.1 58337492 3252083 1185188..1185832 1 NC_006814.3 RepA; metalloprotease, insulinase; temperature-sensitive replication protein 1185832 repA 3252083 repA Lactobacillus acidophilus NCFM temperature-sensitive replication protein YP_194077.1 1185188 D 272621 CDS YP_194078.1 58337493 3251487 complement(1185863..1186726) 1 NC_006814.3 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 1186726 thrB 3251487 thrB Lactobacillus acidophilus NCFM homoserine kinase YP_194078.1 1185863 R 272621 CDS YP_194079.1 58337494 3252097 complement(1186751..1187983) 1 NC_006814.3 homoserine dehydrogenase Hdh 1187983 3252097 LBA1212 Lactobacillus acidophilus NCFM homoserine dehydrogenase Hdh YP_194079.1 1186751 R 272621 CDS YP_194080.1 58337495 3252065 1188099..1189589 1 NC_006814.3 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 1189589 thrC 3252065 thrC Lactobacillus acidophilus NCFM threonine synthase YP_194080.1 1188099 D 272621 CDS YP_194081.1 58337496 3252266 1189606..1190967 1 NC_006814.3 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; aspartate kinase 1190967 3252266 LBA1215 Lactobacillus acidophilus NCFM aspartate kinase YP_194081.1 1189606 D 272621 CDS YP_194082.1 58337497 3252282 complement(1191339..1192964) 1 NC_006814.3 pheromone-peptide binding protein 1192964 3252282 LBA1216 Lactobacillus acidophilus NCFM pheromone-peptide binding protein YP_194082.1 1191339 R 272621 CDS YP_194083.1 58337498 3252110 1194082..1194696 1 NC_006814.3 acetyltransferase 1194696 3252110 LBA1217 Lactobacillus acidophilus NCFM acetyltransferase YP_194083.1 1194082 D 272621 CDS YP_194084.1 58337499 3252111 complement(1195048..1197141) 1 NC_006814.3 mucus binding protein 1197141 3252111 LBA1218 Lactobacillus acidophilus NCFM mucus binding protein YP_194084.1 1195048 R 272621 CDS YP_194085.1 58337500 3252076 complement(1197150..1198427) 1 NC_006814.3 lipase 1198427 3252076 LBA1219 Lactobacillus acidophilus NCFM lipase YP_194085.1 1197150 R 272621 CDS YP_194086.1 58337501 3252327 1198571..1199896 1 NC_006814.3 COG1249 Pyruvate-2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component; pyridine mercuric reductase 1199896 3252327 LBA1220 Lactobacillus acidophilus NCFM pyridine mercuric reductase YP_194086.1 1198571 D 272621 CDS YP_194087.1 58337502 3252325 complement(1200080..1200181) 1 NC_006814.3 hypothetical protein 1200181 3252325 LBA1221 Lactobacillus acidophilus NCFM hypothetical protein YP_194087.1 1200080 R 272621 CDS YP_194090.1 58337505 3252150 complement(1201704..1203209) 1 NC_006814.3 hypothetical protein 1203209 3252150 LBA1225 Lactobacillus acidophilus NCFM hypothetical protein YP_194090.1 1201704 R 272621 CDS YP_194091.1 58337506 3252181 complement(1203279..1203947) 1 NC_006814.3 hypothetical Cytosolic protein; hypothetical protein 1203947 3252181 LBA1226 Lactobacillus acidophilus NCFM hypothetical protein YP_194091.1 1203279 R 272621 CDS YP_194092.1 58337507 3252185 complement(1204051..1204599) 1 NC_006814.3 similar to complement component C7 precursor; hypothetical protein 1204599 3252185 LBA1227 Lactobacillus acidophilus NCFM hypothetical protein YP_194092.1 1204051 R 272621 CDS YP_194093.1 58337508 3252182 complement(1204689..1205309) 1 NC_006814.3 transcriptional regulator; hypothetical protein 1205309 3252182 LBA1229 Lactobacillus acidophilus NCFM hypothetical protein YP_194093.1 1204689 R 272621 CDS YP_194094.1 58337509 3252172 complement(1205299..1205460) 1 NC_006814.3 hypothetical protein 1205460 3252172 LBA1230 Lactobacillus acidophilus NCFM hypothetical protein YP_194094.1 1205299 R 272621 CDS YP_194095.1 58337510 3252175 complement(1205481..1206647) 1 NC_006814.3 hypothetical protein 1206647 3252175 LBA1231 Lactobacillus acidophilus NCFM hypothetical protein YP_194095.1 1205481 R 272621 CDS YP_194096.1 58337511 3252243 complement(1206717..1207259) 1 NC_006814.3 apo-citrate lyase 1207259 citX 3252243 citX Lactobacillus acidophilus NCFM apo-citrate lyase YP_194096.1 1206717 R 272621 CDS YP_194097.1 58337512 3252170 complement(1207292..1208143) 1 NC_006814.3 transcriptional regulator 1208143 lysR 3252170 lysR Lactobacillus acidophilus NCFM transcriptional regulator YP_194097.1 1207292 R 272621 CDS YP_194098.1 58337513 3252156 1208271..1210544 1 NC_006814.3 cation-transporting ATPase 1210544 3252156 LBA1234 Lactobacillus acidophilus NCFM cation-transporting ATPase YP_194098.1 1208271 D 272621 CDS YP_194099.1 58337514 3252167 complement(1210589..1211131) 1 NC_006814.3 cell envelope-associated protein PrtH; lactocepin S-layer protein 1211131 3252167 LBA1235 Lactobacillus acidophilus NCFM lactocepin S-layer protein YP_194099.1 1210589 R 272621 CDS YP_194100.1 58337515 3252218 1211227..1212717 1 NC_006814.3 cardiolipin synthase Cls 1212717 3252218 LBA1236 Lactobacillus acidophilus NCFM cardiolipin synthase Cls YP_194100.1 1211227 D 272621 CDS YP_194101.1 58337516 3252180 1212837..1213625 1 NC_006814.3 MetA; homoserine O-succinyltransferase 1213625 metA 3252180 metA Lactobacillus acidophilus NCFM homoserine O-succinyltransferase YP_194101.1 1212837 D 272621 CDS YP_194102.1 58337517 3252198 1213638..1214567 1 NC_006814.3 cysteine synthase 1214567 3252198 LBA1238 Lactobacillus acidophilus NCFM cysteine synthase YP_194102.1 1213638 D 272621 CDS YP_194103.1 58337518 3252203 1214682..1215773 1 NC_006814.3 hypothetical protein 1215773 3252203 LBA1239 Lactobacillus acidophilus NCFM hypothetical protein YP_194103.1 1214682 D 272621 CDS YP_194104.1 58337519 3252148 complement(1215819..1216634) 1 NC_006814.3 catalyzes the reversible formation of 2'-(5''-triphosphoribosyl)-3'dephospho-CoA from 3-dephospho-CoA; triphosphoribosyl-dephospho-CoA synthase 1216634 citG 3252148 citG Lactobacillus acidophilus NCFM triphosphoribosyl-dephospho-CoA synthase YP_194104.1 1215819 R 272621 CDS YP_194105.1 58337520 3252184 complement(1217331..1217777) 1 NC_006814.3 hypothetical protein 1217777 3252184 LBA1241 Lactobacillus acidophilus NCFM hypothetical protein YP_194105.1 1217331 R 272621 CDS YP_194106.1 58337521 3252225 complement(1217850..1218377) 1 NC_006814.3 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 1218377 aprT 3252225 aprT Lactobacillus acidophilus NCFM adenine phosphoribosyltransferase YP_194106.1 1217850 R 272621 CDS YP_194107.1 58337522 3252232 complement(1218482..1220755) 1 NC_006814.3 RecJ; COG0608 Single-stranded DNA-specific exonuclease; single-stranded-DNA-specific exonuclease 1220755 recJ 3252232 recJ Lactobacillus acidophilus NCFM single-stranded-DNA-specific exonuclease YP_194107.1 1218482 R 272621 CDS YP_194108.1 58337523 3252234 complement(1220877..1221566) 1 NC_006814.3 SrtA; sortase 1221566 srtA 3252234 srtA Lactobacillus acidophilus NCFM sortase YP_194108.1 1220877 R 272621 CDS YP_194109.1 58337524 3252191 complement(1221739..1223577) 1 NC_006814.3 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 1223577 lepA 3252191 lepA Lactobacillus acidophilus NCFM GTP-binding protein LepA YP_194109.1 1221739 R 272621 CDS YP_194110.1 58337525 3252245 complement(1223713..1224867) 1 NC_006814.3 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 1224867 dnaJ 3252245 dnaJ Lactobacillus acidophilus NCFM molecular chaperone DnaJ YP_194110.1 1223713 R 272621 CDS YP_194111.1 58337526 3252240 complement(1224951..1226795) 1 NC_006814.3 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 1226795 dnaK 3252240 dnaK Lactobacillus acidophilus NCFM molecular chaperone DnaK YP_194111.1 1224951 R 272621 CDS YP_194112.1 58337527 3252164 complement(1226811..1227395) 1 NC_006814.3 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 1227395 grpE 3252164 grpE Lactobacillus acidophilus NCFM heat shock protein GrpE YP_194112.1 1226811 R 272621 CDS YP_194113.1 58337528 3252236 complement(1227408..1228457) 1 NC_006814.3 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 1228457 hrcA 3252236 hrcA Lactobacillus acidophilus NCFM heat-inducible transcription repressor YP_194113.1 1227408 R 272621 CDS YP_194114.1 58337529 3252238 complement(1228557..1230068) 1 NC_006814.3 ABC transporter ATP-binding protein 1230068 3252238 LBA1250 Lactobacillus acidophilus NCFM ABC transporter ATP-binding protein YP_194114.1 1228557 R 272621 CDS YP_194115.1 58337530 3252063 1230067..1230279 1 NC_006814.3 hypothetical protein 1230279 3252063 LBA1251 Lactobacillus acidophilus NCFM hypothetical protein YP_194115.1 1230067 D 272621 CDS YP_194116.1 58337531 3252231 complement(1230319..1231248) 1 NC_006814.3 COG0196 FAD synthase; riboflavin kinase 1231248 ribC 3252231 ribC Lactobacillus acidophilus NCFM riboflavin kinase YP_194116.1 1230319 R 272621 CDS YP_194117.1 58337532 3252227 complement(1231269..1232162) 1 NC_006814.3 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 1232162 truB 3252227 truB Lactobacillus acidophilus NCFM tRNA pseudouridine synthase B YP_194117.1 1231269 R 272621 CDS YP_194118.1 58337533 3252193 complement(1232213..1232578) 1 NC_006814.3 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 1232578 rbfA 3252193 rbfA Lactobacillus acidophilus NCFM ribosome-binding factor A YP_194118.1 1232213 R 272621 CDS YP_194119.1 58337534 3252165 complement(1232598..1235231) 1 NC_006814.3 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 1235231 infB 3252165 infB Lactobacillus acidophilus NCFM translation initiation factor IF-2 YP_194119.1 1232598 R 272621 CDS YP_194120.1 58337535 3252205 complement(1235236..1235547) 1 NC_006814.3 L7A family ribosomal protein 1235547 3252205 LBA1256 Lactobacillus acidophilus NCFM L7A family ribosomal protein YP_194120.1 1235236 R 272621 CDS YP_194121.1 58337536 3252224 complement(1235550..1235846) 1 NC_006814.3 COG2740 Predicted nucleic-acid-binding protein; hypothetical protein 1235846 3252224 LBA1258 Lactobacillus acidophilus NCFM hypothetical protein YP_194121.1 1235550 R 272621 CDS YP_194122.1 58337537 3252246 complement(1235855..1237024) 1 NC_006814.3 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 1237024 nusA 3252246 nusA Lactobacillus acidophilus NCFM transcription elongation factor NusA YP_194122.1 1235855 R 272621 CDS YP_194123.1 58337538 3252443 complement(1237044..1237520) 1 NC_006814.3 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 1237520 3252443 LBA1260 Lactobacillus acidophilus NCFM hypothetical protein YP_194123.1 1237044 R 272621 CDS YP_194124.1 58337539 3252248 complement(1237623..1241936) 1 NC_006814.3 DNA polymerase III subunit alpha 1241936 3252248 LBA1261 Lactobacillus acidophilus NCFM DNA polymerase III subunit alpha YP_194124.1 1237623 R 272621 CDS YP_194125.1 58337540 3252263 complement(1241942..1243639) 1 NC_006814.3 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 1243639 3252263 LBA1262 Lactobacillus acidophilus NCFM prolyl-tRNA synthetase YP_194125.1 1241942 R 272621 CDS YP_194126.1 58337541 3252212 complement(1243681..1244937) 1 NC_006814.3 enhanced expression of pheromone protein eep 1244937 3252212 LBA1263 Lactobacillus acidophilus NCFM enhanced expression of pheromone protein eep YP_194126.1 1243681 R 272621 CDS YP_194127.1 58337542 3252253 complement(1244949..1245764) 1 NC_006814.3 CdsA; COG0575 CDP-diglyceride synthetase; phosphatidate cytidylyltransferase 1245764 cdsA 3252253 cdsA Lactobacillus acidophilus NCFM phosphatidate cytidylyltransferase YP_194127.1 1244949 R 272621 CDS YP_194128.1 58337543 3252315 complement(1245766..1246500) 1 NC_006814.3 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 1246500 3252315 LBA1266 Lactobacillus acidophilus NCFM undecaprenyl pyrophosphate synthase YP_194128.1 1245766 R 272621 CDS YP_194129.1 58337544 3252333 complement(1246567..1247061) 1 NC_006814.3 COG0233 Ribosome recycling factor; ribosome recycling factor Rrf 1247061 3252333 LBA1267 Lactobacillus acidophilus NCFM ribosome recycling factor Rrf YP_194129.1 1246567 R 272621 CDS YP_194130.1 58337545 3252326 complement(1247061..1247786) 1 NC_006814.3 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 1247786 pyrH 3252326 pyrH Lactobacillus acidophilus NCFM uridylate kinase YP_194130.1 1247061 R 272621 CDS YP_194131.1 58337546 3253109 complement(1247957..1248982) 1 NC_006814.3 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 1248982 tsf 3253109 tsf Lactobacillus acidophilus NCFM elongation factor Ts YP_194131.1 1247957 R 272621 CDS YP_194132.1 58337547 3252335 complement(1249022..1249798) 1 NC_006814.3 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 1249798 rpsB 3252335 rpsB Lactobacillus acidophilus NCFM 30S ribosomal protein S2 YP_194132.1 1249022 R 272621 CDS YP_194133.1 58337548 3252296 complement(1249962..1250993) 1 NC_006814.3 COG4123 Predicted O-methyltransferase; hypothetical protein 1250993 3252296 LBA1271 Lactobacillus acidophilus NCFM hypothetical protein YP_194133.1 1249962 R 272621 CDS YP_194134.1 58337549 3252342 1251057..1251671 1 NC_006814.3 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; acyltransferase 1251671 3252342 LBA1272 Lactobacillus acidophilus NCFM acyltransferase YP_194134.1 1251057 D 272621 CDS YP_194135.1 58337550 3252316 1251773..1252954 1 NC_006814.3 cyclopropane-fatty-acyl-phospholipid synthase 1252954 3252316 LBA1274 Lactobacillus acidophilus NCFM cyclopropane-fatty-acyl-phospholipid synthase YP_194135.1 1251773 D 272621 CDS YP_194136.1 58337551 3252249 complement(1253002..1254945) 1 NC_006814.3 PepO; Neutral endopeptidase (PepO); neutral endopeptidase 1254945 pepO 3252249 pepO Lactobacillus acidophilus NCFM neutral endopeptidase YP_194136.1 1253002 R 272621 CDS YP_194137.1 58337552 3252338 complement(1255032..1256726) 1 NC_006814.3 ABC transporter ATP-binding protein/permease 1256726 3252338 LBA1276 Lactobacillus acidophilus NCFM ABC transporter ATP-binding protein/permease YP_194137.1 1255032 R 272621 CDS YP_194138.1 58337553 3252322 complement(1256827..1258593) 1 NC_006814.3 ABC transporter ATP-binding protein/permease 1258593 3252322 LBA1277 Lactobacillus acidophilus NCFM ABC transporter ATP-binding protein/permease YP_194138.1 1256827 R 272621 CDS YP_194139.1 58337554 3252317 complement(1258677..1258895) 1 NC_006814.3 hypothetical protein 1258895 3252317 LBA1278 Lactobacillus acidophilus NCFM hypothetical protein YP_194139.1 1258677 R 272621 CDS YP_194140.1 58337555 3252321 complement(1258961..1259221) 1 NC_006814.3 COG4224 Uncharacterized protein conserved in bacteria; hypothetical protein 1259221 3252321 LBA1279 Lactobacillus acidophilus NCFM hypothetical protein YP_194140.1 1258961 R 272621 CDS YP_194141.1 58337556 3252363 1259370..1259996 1 NC_006814.3 Represses a number of genes involved in the response to DNA damage; LexA repressor 1259996 lexA 3252363 lexA Lactobacillus acidophilus NCFM LexA repressor YP_194141.1 1259370 D 272621 CDS YP_194142.1 58337557 3252329 complement(1260043..1260801) 1 NC_006814.3 acyl-CoA thioesterase 1260801 3252329 LBA1281 Lactobacillus acidophilus NCFM acyl-CoA thioesterase YP_194142.1 1260043 R 272621 CDS YP_194143.1 58337558 3252323 complement(1260794..1261453) 1 NC_006814.3 phage related; COG1573 Uracil-DNA glycosylase; DNA polymerase 1261453 3252323 LBA1282 Lactobacillus acidophilus NCFM DNA polymerase YP_194143.1 1260794 R 272621 CDS YP_194144.1 58337559 3252358 complement(1261749..1262681) 1 NC_006814.3 glycosyl transferase 1262681 3252358 LBA1283 Lactobacillus acidophilus NCFM glycosyl transferase YP_194144.1 1261749 R 272621 CDS YP_194145.1 58337560 3252383 complement(1262683..1264431) 1 NC_006814.3 cell division protein 1264431 3252383 LBA1284 Lactobacillus acidophilus NCFM cell division protein YP_194145.1 1262683 R 272621 CDS YP_194146.1 58337561 3252344 complement(1264465..1264893) 1 NC_006814.3 hypothetical protein 1264893 3252344 LBA1285 Lactobacillus acidophilus NCFM hypothetical protein YP_194146.1 1264465 R 272621 CDS YP_194147.1 58337562 3252396 complement(1265100..1265447) 1 NC_006814.3 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1265447 rplS 3252396 rplS Lactobacillus acidophilus NCFM 50S ribosomal protein L19 YP_194147.1 1265100 R 272621 CDS YP_194148.1 58337563 3252426 complement(1265581..1266309) 1 NC_006814.3 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 1266309 trmD 3252426 trmD Lactobacillus acidophilus NCFM tRNA (guanine-N(1)-)-methyltransferase YP_194148.1 1265581 R 272621 CDS YP_194149.1 58337564 3252376 complement(1266299..1266814) 1 NC_006814.3 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 1266814 rimM 3252376 rimM Lactobacillus acidophilus NCFM 16S rRNA-processing protein RimM YP_194149.1 1266299 R 272621 CDS YP_194150.1 58337565 3252411 complement(1266886..1267158) 1 NC_006814.3 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 1267158 rpsP 3252411 rpsP Lactobacillus acidophilus NCFM 30S ribosomal protein S16 YP_194150.1 1266886 R 272621 CDS YP_194151.1 58337566 3252420 complement(1267248..1268678) 1 NC_006814.3 signal recognition protein Ffh 1268678 3252420 LBA1290 Lactobacillus acidophilus NCFM signal recognition protein Ffh YP_194151.1 1267248 R 272621 CDS YP_194152.1 58337567 3252398 complement(1268682..1269023) 1 NC_006814.3 hypothetical protein 1269023 3252398 LBA1291 Lactobacillus acidophilus NCFM hypothetical protein YP_194152.1 1268682 R 272621 CDS YP_194153.1 58337568 3252371 1269216..1270643 1 NC_006814.3 aa transporter 1270643 3252371 LBA1292 Lactobacillus acidophilus NCFM aa transporter YP_194153.1 1269216 D 272621 CDS YP_194154.1 58337569 3252397 complement(1270706..1271113) 1 NC_006814.3 transcriptional regulator 1271113 3252397 LBA1293 Lactobacillus acidophilus NCFM transcriptional regulator YP_194154.1 1270706 R 272621 CDS YP_194155.1 58337570 3252382 complement(1271180..1272601) 1 NC_006814.3 COG4690 Dipeptidase; dipeptidase 1272601 3252382 LBA1294 Lactobacillus acidophilus NCFM dipeptidase YP_194155.1 1271180 R 272621 CDS YP_194156.1 58337571 3252432 complement(1272643..1273938) 1 NC_006814.3 FtsY; cell division protein 1273938 ftsY 3252432 ftsY Lactobacillus acidophilus NCFM cell division protein YP_194156.1 1272643 R 272621 CDS YP_194157.1 58337572 3252377 complement(1273939..1277508) 1 NC_006814.3 COG1196 Chromosome segregation ATPases; chromosome segregation protein Smc 1277508 3252377 LBA1296 Lactobacillus acidophilus NCFM chromosome segregation protein Smc YP_194157.1 1273939 R 272621 CDS YP_194158.1 58337573 3252409 complement(1277521..1278207) 1 NC_006814.3 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 1278207 rnc 3252409 rnc Lactobacillus acidophilus NCFM ribonuclease III YP_194158.1 1277521 R 272621 CDS YP_194159.1 58337574 3252437 1278259..1278360 1 NC_006814.3 hypothetical protein 1278360 3252437 LBA1298 Lactobacillus acidophilus NCFM hypothetical protein YP_194159.1 1278259 D 272621 CDS YP_194160.1 58337575 3252425 1278329..1279711 1 NC_006814.3 transposase 1279711 3252425 LBA1299 Lactobacillus acidophilus NCFM transposase YP_194160.1 1278329 D 272621 CDS YP_194161.1 58337576 3252424 complement(1279788..1281545) 1 NC_006814.3 OppA; oligopeptide ABC transporter substrate binding protein 1281545 oppA 3252424 oppA Lactobacillus acidophilus NCFM oligopeptide ABC transporter substrate binding protein YP_194161.1 1279788 R 272621 CDS YP_194162.1 58337577 3252444 complement(1281747..1283516) 1 NC_006814.3 OppA; oligopeptide ABC transporter substrate binding protein 1283516 oppA 3252444 oppA Lactobacillus acidophilus NCFM oligopeptide ABC transporter substrate binding protein YP_194162.1 1281747 R 272621 CDS YP_194163.1 58337578 3252406 complement(1283728..1284657) 1 NC_006814.3 OppC; oligopeptide ABC transporter permease 1284657 oppC 3252406 oppC Lactobacillus acidophilus NCFM oligopeptide ABC transporter permease YP_194163.1 1283728 R 272621 CDS YP_194164.1 58337579 3252412 complement(1284672..1285631) 1 NC_006814.3 OppB; oligopeptide transport protein 1285631 oppB 3252412 oppB Lactobacillus acidophilus NCFM oligopeptide transport protein YP_194164.1 1284672 R 272621 CDS YP_194165.1 58337580 3252408 complement(1285634..1286620) 1 NC_006814.3 OppF; oligopeptide ABC transporter ATP-binding protein 1286620 oppF 3252408 oppF Lactobacillus acidophilus NCFM oligopeptide ABC transporter ATP-binding protein YP_194165.1 1285634 R 272621 CDS YP_194166.1 58337581 3252410 complement(1286624..1287655) 1 NC_006814.3 OppD; oligopeptide ABC transporter ATP-binding protein 1287655 oppD 3252410 oppD Lactobacillus acidophilus NCFM oligopeptide ABC transporter ATP-binding protein YP_194166.1 1286624 R 272621 CDS YP_194167.1 58337582 3252380 complement(1287772..1288014) 1 NC_006814.3 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1288014 acpP 3252380 acpP Lactobacillus acidophilus NCFM acyl carrier protein YP_194167.1 1287772 R 272621 CDS YP_194168.1 58337583 3252552 complement(1288047..1289048) 1 NC_006814.3 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 1289048 plsX 3252552 plsX Lactobacillus acidophilus NCFM glycerol-3-phosphate acyltransferase PlsX YP_194168.1 1288047 R 272621 CDS YP_194169.1 58337584 3252556 complement(1289068..1291104) 1 NC_006814.3 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 1291104 recG 3252556 recG Lactobacillus acidophilus NCFM ATP-dependent DNA helicase RecG YP_194169.1 1289068 R 272621 CDS YP_194170.1 58337585 3252616 complement(1291109..1292770) 1 NC_006814.3 dihydroacetone kinase 1292770 3252616 LBA1310 Lactobacillus acidophilus NCFM dihydroacetone kinase YP_194170.1 1291109 R 272621 CDS YP_194171.1 58337586 3252595 complement(1292792..1293154) 1 NC_006814.3 conserved hypothetical protein; alkaline shock protein 1293154 3252595 LBA1311 Lactobacillus acidophilus NCFM alkaline shock protein YP_194171.1 1292792 R 272621 CDS YP_194172.1 58337587 3252446 1293322..1293507 1 NC_006814.3 required for 70S ribosome assembly; 50S ribosomal protein L28 1293507 rpmB 3252446 rpmB Lactobacillus acidophilus NCFM 50S ribosomal protein L28 YP_194172.1 1293322 D 272621 CDS YP_194173.1 58337588 3252365 complement(1293618..1293923) 1 NC_006814.3 ATP-dependent Lon protease; hypothetical protein 1293923 3252365 LBA1313 Lactobacillus acidophilus NCFM hypothetical protein YP_194173.1 1293618 R 272621 CDS YP_194174.1 58337589 3252518 complement(1293970..1294656) 1 NC_006814.3 COG1564 Thiamine pyrophosphokinase; pyrophosphokinase 1294656 3252518 LBA1314 Lactobacillus acidophilus NCFM pyrophosphokinase YP_194174.1 1293970 R 272621 CDS YP_194175.1 58337590 3252508 complement(1294656..1295306) 1 NC_006814.3 ribulose-5-phosphate 3-epimerase; ribulose-phosphate 3-epimerase 1295306 3252508 LBA1315 Lactobacillus acidophilus NCFM ribulose-phosphate 3-epimerase YP_194175.1 1294656 R 272621 CDS YP_194176.1 58337591 3252521 complement(1295317..1296207) 1 NC_006814.3 COG1162 Predicted GTPases; hypothetical protein 1296207 3252521 LBA1316 Lactobacillus acidophilus NCFM hypothetical protein YP_194176.1 1295317 R 272621 CDS YP_194177.1 58337592 3252519 complement(1296209..1298233) 1 NC_006814.3 serine-threonine protein kinase 1298233 3252519 LBA1317 Lactobacillus acidophilus NCFM serine-threonine protein kinase YP_194177.1 1296209 R 272621 CDS YP_194178.1 58337593 3252494 complement(1298223..1298978) 1 NC_006814.3 COG0631 Serine-threonine protein phosphatase; protein serine-threonine phosphatase 1298978 3252494 LBA1318 Lactobacillus acidophilus NCFM protein serine-threonine phosphatase YP_194178.1 1298223 R 272621 CDS YP_194179.1 58337594 3252512 complement(1298983..1300350) 1 NC_006814.3 rRNA methylase 1300350 3252512 LBA1319 Lactobacillus acidophilus NCFM rRNA methylase YP_194179.1 1298983 R 272621 CDS YP_194180.1 58337595 3252525 complement(1300301..1301245) 1 NC_006814.3 COG0223 Methionyl-tRNA formyltransferase; methionyl-tRNA formyltransferase FMT 1301245 3252525 LBA1321 Lactobacillus acidophilus NCFM methionyl-tRNA formyltransferase FMT YP_194180.1 1300301 R 272621 CDS YP_194181.1 58337596 3252510 complement(1301258..1303657) 1 NC_006814.3 PriA; primosomal replication factor 1303657 priA 3252510 priA Lactobacillus acidophilus NCFM primosomal replication factor YP_194181.1 1301258 R 272621 CDS YP_194182.1 58337597 3252522 complement(1303708..1303932) 1 NC_006814.3 RpoZ; COG1758 DNA-directed RNA polymerase, subunit K-omega; DNA-directed RNA polymerase subunit omega 1303932 rpoZ 3252522 rpoZ Lactobacillus acidophilus NCFM DNA-directed RNA polymerase subunit omega YP_194182.1 1303708 R 272621 CDS YP_194183.1 58337598 3252535 complement(1303935..1304549) 1 NC_006814.3 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 1304549 gmk 3252535 gmk Lactobacillus acidophilus NCFM guanylate kinase YP_194183.1 1303935 R 272621 CDS YP_194184.1 58337599 3252480 complement(1304660..1305097) 1 NC_006814.3 hypothetical protein 1305097 3252480 LBA1326 Lactobacillus acidophilus NCFM hypothetical protein YP_194184.1 1304660 R 272621 CDS YP_194185.1 58337600 3252511 complement(1305090..1306772) 1 NC_006814.3 RecN; DNA repair protein 1306772 recN 3252511 recN Lactobacillus acidophilus NCFM DNA repair protein YP_194185.1 1305090 R 272621 CDS YP_194186.1 58337601 3252493 complement(1306783..1307595) 1 NC_006814.3 COG1189 Predicted rRNA methylase; hemolysin-like protein 1307595 3252493 LBA1328 Lactobacillus acidophilus NCFM hemolysin-like protein YP_194186.1 1306783 R 272621 CDS YP_194187.1 58337602 3252489 complement(1307596..1308465) 1 NC_006814.3 COG0142 Geranylgeranyl pyrophosphate synthase; geranylgeranyl diphosphate (GGPP) synthase 1308465 3252489 LBA1329 Lactobacillus acidophilus NCFM geranylgeranyl diphosphate (GGPP) synthase YP_194187.1 1307596 R 272621 CDS YP_194188.1 58337603 3252530 complement(1308468..1308710) 1 NC_006814.3 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 1308710 xseB 3252530 xseB Lactobacillus acidophilus NCFM exodeoxyribonuclease VII small subunit YP_194188.1 1308468 R 272621 CDS YP_194189.1 58337604 3252477 complement(1308691..1310058) 1 NC_006814.3 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 1310058 xseA 3252477 xseA Lactobacillus acidophilus NCFM exodeoxyribonuclease VII large subunit YP_194189.1 1308691 R 272621 CDS YP_194190.1 58337605 3252498 complement(1310045..1310896) 1 NC_006814.3 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 1310896 folD 3252498 folD Lactobacillus acidophilus NCFM bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_194190.1 1310045 R 272621 CDS YP_194191.1 58337606 3252517 complement(1311190..1311582) 1 NC_006814.3 NusB; COG0781 transcriptional termination factor; transcriptional termination factor 1311582 nusB 3252517 nusB Lactobacillus acidophilus NCFM transcriptional termination factor YP_194191.1 1311190 R 272621 CDS YP_194192.1 58337607 3252483 complement(1311582..1312016) 1 NC_006814.3 alkaline shock protein 1312016 3252483 LBA1334 Lactobacillus acidophilus NCFM alkaline shock protein YP_194192.1 1311582 R 272621 CDS YP_194193.1 58337608 3252470 complement(1312035..1312604) 1 NC_006814.3 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 1312604 3252470 LBA1335 Lactobacillus acidophilus NCFM elongation factor P YP_194193.1 1312035 R 272621 CDS YP_194194.1 58337609 3252520 complement(1312685..1313794) 1 NC_006814.3 COG0006 Xaa-Pro aminopeptidase; X-Pro dipeptidase 1313794 pepP 3252520 pepP Lactobacillus acidophilus NCFM X-Pro dipeptidase YP_194194.1 1312685 R 272621 CDS YP_194195.1 58337610 3252421 complement(1313919..1314209) 1 NC_006814.3 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 1314209 rpmA 3252421 rpmA Lactobacillus acidophilus NCFM 50S ribosomal protein L27 YP_194195.1 1313919 R 272621 CDS YP_194196.1 58337611 3252385 complement(1314228..1314539) 1 NC_006814.3 50S ribosomal protein L21 1314539 rplU 3252385 rplU Lactobacillus acidophilus NCFM 50S ribosomal protein L21 YP_194196.1 1314228 R 272621 CDS YP_194197.1 58337612 3252613 complement(1314706..1315542) 1 NC_006814.3 COG1284 Uncharacterized conserved protein; hypothetical protein 1315542 3252613 LBA1339 Lactobacillus acidophilus NCFM hypothetical protein YP_194197.1 1314706 R 272621 CDS YP_194198.1 58337613 3252532 complement(1315629..1317002) 1 NC_006814.3 V-type sodium ATP synthase subunit 1317002 3252532 LBA1340 Lactobacillus acidophilus NCFM V-type sodium ATP synthase subunit YP_194198.1 1315629 R 272621 CDS YP_194199.1 58337614 3252630 1317133..1318158 1 NC_006814.3 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 1318158 ilvE 3252630 ilvE Lactobacillus acidophilus NCFM branched-chain amino acid aminotransferase YP_194199.1 1317133 D 272621 CDS YP_194200.1 58337615 3252651 complement(1318209..1318388) 1 NC_006814.3 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown; 4-oxalocrotonate tautomerase 1318388 xlyH 3252651 xlyH Lactobacillus acidophilus NCFM 4-oxalocrotonate tautomerase YP_194200.1 1318209 R 272621 CDS YP_194201.1 58337616 3252657 complement(1318462..1319043) 1 NC_006814.3 potential frameshift to 1344; protein PepQ 1319043 3252657 LBA1343 Lactobacillus acidophilus NCFM protein PepQ YP_194201.1 1318462 R 272621 CDS YP_194202.1 58337617 3252635 complement(1319080..1319661) 1 NC_006814.3 potential frameshift to 1343; hypothetical protein; protein PepQ 1319661 3252635 LBA1344 Lactobacillus acidophilus NCFM protein PepQ YP_194202.1 1319080 R 272621 CDS YP_194203.1 58337618 3252696 complement(1319724..1319993) 1 NC_006814.3 potential frameshift to 1346; OppA; oligopeptide ABC transporter substrate bindingprotein 1319993 3252696 LBA1345 Lactobacillus acidophilus NCFM oligopeptide ABC transporter substrate bindingprotein YP_194203.1 1319724 R 272621 CDS YP_194204.1 58337619 3252702 complement(1319987..1320358) 1 NC_006814.3 potential frameshift to 1345; OppA; oligopeptide ABC transporter substrate binding protein 1320358 oppA 3252702 oppA Lactobacillus acidophilus NCFM oligopeptide ABC transporter substrate binding protein YP_194204.1 1319987 R 272621 CDS YP_194205.1 58337620 3252627 complement(1320683..1321237) 1 NC_006814.3 potential frameshift to 1345; OppA; peptide binding protein 1321237 oppA 3252627 oppA Lactobacillus acidophilus NCFM peptide binding protein YP_194205.1 1320683 R 272621 CDS YP_194206.1 58337621 3252618 complement(1321637..1322419) 1 NC_006814.3 COG3231 Aminoglycoside phosphotransferase; kanamycin kinase 1322419 3252618 LBA1348 Lactobacillus acidophilus NCFM kanamycin kinase YP_194206.1 1321637 R 272621 CDS YP_194207.1 58337622 3252606 complement(1322428..1324224) 1 NC_006814.3 COG4907 Predicted membrane protein; hypothetical protein 1324224 3252606 LBA1349 Lactobacillus acidophilus NCFM hypothetical protein YP_194207.1 1322428 R 272621 CDS YP_194208.1 58337623 3252617 complement(1324235..1325134) 1 NC_006814.3 CinII; alpha/beta hydrolase 1325134 3252617 LBA1350 Lactobacillus acidophilus NCFM alpha/beta hydrolase YP_194208.1 1324235 R 272621 CDS YP_194211.1 58337626 3252626 1326922..1327950 1 NC_006814.3 COG2364 Predicted membrane protein; hypothetical protein 1327950 3252626 LBA1353 Lactobacillus acidophilus NCFM hypothetical protein YP_194211.1 1326922 D 272621 CDS YP_194212.1 58337627 3252700 complement(1328010..1328114) 1 NC_006814.3 hypothetical protein 1328114 3252700 LBA1354 Lactobacillus acidophilus NCFM hypothetical protein YP_194212.1 1328010 R 272621 CDS YP_194213.1 58337628 3252703 1328354..1329250 1 NC_006814.3 COG0657 Esterase-lipase; lipase 1329250 lipA 3252703 lipA Lactobacillus acidophilus NCFM lipase YP_194213.1 1328354 D 272621 CDS YP_194214.1 58337629 3252724 1329261..1329620 1 NC_006814.3 Arsenate reductase; arsenate reductase 1329620 3252724 LBA1356 Lactobacillus acidophilus NCFM arsenate reductase YP_194214.1 1329261 D 272621 CDS YP_194215.1 58337630 3252730 complement(1329655..1331238) 1 NC_006814.3 ABC transporter ATP-binding protein/permease 1331238 3252730 LBA1357 Lactobacillus acidophilus NCFM ABC transporter ATP-binding protein/permease YP_194215.1 1329655 R 272621 CDS YP_194216.1 58337631 3252712 complement(1331238..1332815) 1 NC_006814.3 ABC transporter ATP-binding protein/permease 1332815 3252712 LBA1358 Lactobacillus acidophilus NCFM ABC transporter ATP-binding protein/permease YP_194216.1 1331238 R 272621 CDS YP_194217.1 58337632 3252718 complement(1333148..1333963) 1 NC_006814.3 hypothetical protein 1333963 3252718 LBA1359 Lactobacillus acidophilus NCFM hypothetical protein YP_194217.1 1333148 R 272621 CDS YP_194220.1 58337635 3252620 complement(1336153..1338195) 1 NC_006814.3 beta-galactosidase 1338195 lacA 3252620 lacA Lactobacillus acidophilus NCFM beta-galactosidase YP_194220.1 1336153 R 272621 CDS YP_194221.1 58337636 3252679 complement(1338209..1340488) 1 NC_006814.3 catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides; alpha-xylosidase 1340488 3252679 LBA1365 Lactobacillus acidophilus NCFM alpha-xylosidase YP_194221.1 1338209 R 272621 CDS YP_194222.1 58337637 3252609 complement(1340493..1341983) 1 NC_006814.3 Beta-glucosidase; beta-glucosidase 1341983 3252609 LBA1366 Lactobacillus acidophilus NCFM beta-glucosidase YP_194222.1 1340493 R 272621 CDS YP_194223.1 58337638 3252687 complement(1341973..1342857) 1 NC_006814.3 transcriptional regulator, glucose kinase 1342857 3252687 LBA1367 Lactobacillus acidophilus NCFM transcriptional regulator, glucose kinase YP_194223.1 1341973 R 272621 CDS YP_194224.1 58337639 3252612 1342995..1344140 1 NC_006814.3 xylose operon regulator; transcriptional xylose repressor 1344140 xylR 3252612 xylR Lactobacillus acidophilus NCFM transcriptional xylose repressor YP_194224.1 1342995 D 272621 CDS YP_194225.1 58337640 3252689 1344271..1345524 1 NC_006814.3 PTS system cellobiose-specific transporter subunit IIC 1345524 celB 3252689 celB Lactobacillus acidophilus NCFM PTS system cellobiose-specific transporter subunit IIC YP_194225.1 1344271 D 272621 CDS YP_194226.1 58337641 3252601 complement(1345644..1346255) 1 NC_006814.3 phage-related hypothetical protein; bacteriophage-like protein 1346255 3252601 LBA1370 Lactobacillus acidophilus NCFM bacteriophage-like protein YP_194226.1 1345644 R 272621 CDS YP_194227.1 58337642 3252662 complement(1346635..1347018) 1 NC_006814.3 prophage ps3 protein 01; transcriptional regulator phage-related 1347018 3252662 LBA1371 Lactobacillus acidophilus NCFM transcriptional regulator phage-related YP_194227.1 1346635 R 272621 CDS YP_194228.1 58337643 3252735 complement(1347029..1347322) 1 NC_006814.3 similar to Orf20 Bacteriophage bIL311; bacteriophage-like protein 1347322 3252735 LBA1372 Lactobacillus acidophilus NCFM bacteriophage-like protein YP_194228.1 1347029 R 272621 CDS YP_194229.1 58337644 3252734 1347552..1349933 1 NC_006814.3 catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue; x-prolyl-dipeptidyl aminopeptidase 1349933 pepX 3252734 pepX Lactobacillus acidophilus NCFM x-prolyl-dipeptidyl aminopeptidase YP_194229.1 1347552 D 272621 CDS YP_194230.1 58337645 3252731 complement(1349997..1350434) 1 NC_006814.3 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 1350434 msrA 3252731 msrA Lactobacillus acidophilus NCFM methionine sulfoxide reductase B YP_194230.1 1349997 R 272621 CDS YP_194231.1 58337646 3252670 complement(1350487..1350879) 1 NC_006814.3 hypothetical protein 1350879 3252670 LBA1375 Lactobacillus acidophilus NCFM hypothetical protein YP_194231.1 1350487 R 272621 CDS YP_194232.1 58337647 3252719 complement(1350888..1351751) 1 NC_006814.3 transmembrane protein 1351751 3252719 LBA1376 Lactobacillus acidophilus NCFM transmembrane protein YP_194232.1 1350888 R 272621 CDS YP_194233.1 58337648 3252628 complement(1352001..1355054) 1 NC_006814.3 mucus binding protein 1355054 3252628 LBA1377 Lactobacillus acidophilus NCFM mucus binding protein YP_194233.1 1352001 R 272621 CDS YP_194234.1 58337649 3252647 complement(1355660..1355860) 1 NC_006814.3 biofilm-associated surface protein 1355860 3252647 LBA1378 Lactobacillus acidophilus NCFM biofilm-associated surface protein YP_194234.1 1355660 R 272621 CDS YP_194235.1 58337650 3252607 complement(1356204..1359392) 1 NC_006814.3 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 1359392 carB 3252607 carB Lactobacillus acidophilus NCFM carbamoyl phosphate synthase large subunit YP_194235.1 1356204 R 272621 CDS YP_194236.1 58337651 3252649 complement(1359385..1360470) 1 NC_006814.3 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 1360470 carA 3252649 carA Lactobacillus acidophilus NCFM carbamoyl phosphate synthase small subunit YP_194236.1 1359385 R 272621 CDS YP_194237.1 58337652 3252590 complement(1360471..1361748) 1 NC_006814.3 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 1361748 pyrC 3252590 pyrC Lactobacillus acidophilus NCFM dihydroorotase YP_194237.1 1360471 R 272621 CDS YP_194238.1 58337653 3252677 complement(1361748..1362704) 1 NC_006814.3 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase 1362704 pyrB 3252677 pyrB Lactobacillus acidophilus NCFM aspartate carbamoyltransferase YP_194238.1 1361748 R 272621 CDS YP_194239.1 58337654 3252655 complement(1362845..1363387) 1 NC_006814.3 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase 1363387 pyrR 3252655 pyrR Lactobacillus acidophilus NCFM bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase YP_194239.1 1362845 R 272621 CDS YP_194240.1 58337655 3252605 complement(1363564..1364487) 1 NC_006814.3 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits, similar to the PyrDA subunits and two PyrK subunits; dihydroorotate dehydrogenase 1B 1364487 pyrD 3252605 pyrD Lactobacillus acidophilus NCFM dihydroorotate dehydrogenase 1B YP_194240.1 1363564 R 272621 CDS YP_194241.1 58337656 3252545 1364502..1364594 1 NC_006814.3 hypothetical protein 1364594 3252545 LBA1385 Lactobacillus acidophilus NCFM hypothetical protein YP_194241.1 1364502 D 272621 CDS YP_194242.1 58337657 3252592 1364740..1365447 1 NC_006814.3 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1365447 pyrF 3252592 pyrF Lactobacillus acidophilus NCFM orotidine 5'-phosphate decarboxylase YP_194242.1 1364740 D 272621 CDS YP_194243.1 58337658 3252688 1365447..1366085 1 NC_006814.3 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 1366085 pyrE 3252688 pyrE Lactobacillus acidophilus NCFM orotate phosphoribosyltransferase YP_194243.1 1365447 D 272621 CDS YP_194244.1 58337659 3252602 complement(1366155..1366802) 1 NC_006814.3 COG0702 Predicted nucleoside-diphosphate-sugar epimerases; hypothetical protein 1366802 3252602 LBA1388 Lactobacillus acidophilus NCFM hypothetical protein YP_194244.1 1366155 R 272621 CDS YP_194245.1 58337660 3252599 1367232..1369859 1 NC_006814.3 COG0474 Cation transport ATPase; cation-transporting ATPase 1369859 3252599 LBA1389 Lactobacillus acidophilus NCFM cation-transporting ATPase YP_194245.1 1367232 D 272621 CDS YP_194246.1 58337661 3252593 1369943..1371289 1 NC_006814.3 cloride channel-like protein 1371289 3252593 LBA1390 Lactobacillus acidophilus NCFM cloride channel-like protein YP_194246.1 1369943 D 272621 CDS YP_194247.1 58337662 3252643 1371412..1372080 1 NC_006814.3 hypothetical protein 1372080 3252643 LBA1391 Lactobacillus acidophilus NCFM hypothetical protein YP_194247.1 1371412 D 272621 CDS YP_194248.1 58337663 3252633 complement(1372196..1385176) 1 NC_006814.3 mucus binding protein precursor Mub 1385176 3252633 LBA1392 Lactobacillus acidophilus NCFM mucus binding protein precursor Mub YP_194248.1 1372196 R 272621 CDS YP_194249.1 58337664 3252614 complement(1385479..1385991) 1 NC_006814.3 acetyltransferase 1385991 3252614 LBA1393 Lactobacillus acidophilus NCFM acetyltransferase YP_194249.1 1385479 R 272621 CDS YP_194250.1 58337665 3252717 complement(1386063..1386359) 1 NC_006814.3 GLP_703_9564_7504; hypothetical protein 1386359 3252717 LBA1394 Lactobacillus acidophilus NCFM hypothetical protein YP_194250.1 1386063 R 272621 CDS YP_194251.1 58337666 3252624 1386774..1387625 1 NC_006814.3 outer membrane lipoprotein 1387625 3252624 LBA1395 Lactobacillus acidophilus NCFM outer membrane lipoprotein YP_194251.1 1386774 D 272621 CDS YP_194252.1 58337667 3252765 complement(1387663..1387956) 1 NC_006814.3 conserved domain protein; hypothetical protein 1387956 3252765 LBA1396 Lactobacillus acidophilus NCFM hypothetical protein YP_194252.1 1387663 R 272621 CDS YP_194253.1 58337668 3253056 1388134..1388796 1 NC_006814.3 L-serine dehydratase subunit beta 1388796 sdhB 3253056 sdhB Lactobacillus acidophilus NCFM L-serine dehydratase subunit beta YP_194253.1 1388134 D 272621 CDS YP_194254.1 58337669 3253054 1388810..1389691 1 NC_006814.3 L-serine dehydratase subunit alpha 1389691 sdhA 3253054 sdhA Lactobacillus acidophilus NCFM L-serine dehydratase subunit alpha YP_194254.1 1388810 D 272621 CDS YP_194255.1 58337670 3252755 1389701..1390015 1 NC_006814.3 hypothetical protein 1390015 3252755 LBA1399 Lactobacillus acidophilus NCFM hypothetical protein YP_194255.1 1389701 D 272621 CDS YP_194256.1 58337671 3252764 complement(1390329..1392074) 1 NC_006814.3 OppA; oligopeptide ABC transporter substrate binding protein 1392074 oppA 3252764 oppA Lactobacillus acidophilus NCFM oligopeptide ABC transporter substrate binding protein YP_194256.1 1390329 R 272621 CDS YP_194257.1 58337672 3253053 complement(1392344..1393708) 1 NC_006814.3 Nadh; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; peroxidase (Npx) 1393708 3253053 LBA1401 Lactobacillus acidophilus NCFM peroxidase (Npx) YP_194257.1 1392344 R 272621 CDS YP_194258.1 58337673 3252776 complement(1393975..1394322) 1 NC_006814.3 hypothetical protein 1394322 3252776 LBA1402 Lactobacillus acidophilus NCFM hypothetical protein YP_194258.1 1393975 R 272621 CDS YP_194259.1 58337674 3252773 complement(1394322..1394600) 1 NC_006814.3 hypothetical protein 1394600 3252773 LBA1403 Lactobacillus acidophilus NCFM hypothetical protein YP_194259.1 1394322 R 272621 CDS YP_194260.1 58337675 3253058 complement(1394671..1395309) 1 NC_006814.3 COG0702 Predicted nucleoside-diphosphate-sugar epimerases; oxidoreductase 1395309 3253058 LBA1404 Lactobacillus acidophilus NCFM oxidoreductase YP_194260.1 1394671 R 272621 CDS YP_194261.1 58337676 3252769 complement(1395543..1395884) 1 NC_006814.3 ChpA; ppGpp-regulated growth inhibitor 1395884 chpA 3252769 chpA Lactobacillus acidophilus NCFM ppGpp-regulated growth inhibitor YP_194261.1 1395543 R 272621 CDS YP_194262.1 58337677 3252784 complement(1395995..1396120) 1 NC_006814.3 hypothetical protein 1396120 3252784 LBA1406 Lactobacillus acidophilus NCFM hypothetical protein YP_194262.1 1395995 R 272621 CDS YP_194263.1 58337678 3253063 complement(1396186..1396557) 1 NC_006814.3 hypothetical protein 1396557 3253063 LBA1407 Lactobacillus acidophilus NCFM hypothetical protein YP_194263.1 1396186 R 272621 CDS YP_194264.1 58337679 3253064 complement(1396577..1397203) 1 NC_006814.3 COG4832 Uncharacterized conserved protein; hypothetical protein 1397203 3253064 LBA1408 Lactobacillus acidophilus NCFM hypothetical protein YP_194264.1 1396577 R 272621 CDS YP_194265.1 58337680 3253062 complement(1397386..1398174) 1 NC_006814.3 hypothetical protein 1398174 3253062 LBA1409 Lactobacillus acidophilus NCFM hypothetical protein YP_194265.1 1397386 R 272621 CDS YP_194266.1 58337681 3252787 complement(1398292..1399146) 1 NC_006814.3 transcriptional regulator 1399146 lysR 3252787 lysR Lactobacillus acidophilus NCFM transcriptional regulator YP_194266.1 1398292 R 272621 CDS YP_194267.1 58337682 3252786 1399255..1401369 1 NC_006814.3 fumarate reductase flavoprotein subunit 1401369 3252786 LBA1411 Lactobacillus acidophilus NCFM fumarate reductase flavoprotein subunit YP_194267.1 1399255 D 272621 CDS YP_194268.1 58337683 3252825 complement(1401616..1401771) 1 NC_006814.3 hypothetical protein 1401771 3252825 LBA1412 Lactobacillus acidophilus NCFM hypothetical protein YP_194268.1 1401616 R 272621 CDS YP_194269.1 58337684 3252819 1402240..1403343 1 NC_006814.3 COG2199 FOG GGDEF domain; regulator components 1403343 3252819 LBA1413 Lactobacillus acidophilus NCFM regulator components YP_194269.1 1402240 D 272621 CDS YP_194270.1 58337685 3253066 1403474..1404169 1 NC_006814.3 COG2200 FOG EAL domain; hypothetical protein 1404169 3253066 LBA1414 Lactobacillus acidophilus NCFM hypothetical protein YP_194270.1 1403474 D 272621 CDS YP_194271.1 58337686 3252812 complement(1404207..1405010) 1 NC_006814.3 hypothetical protein 1405010 3252812 LBA1415 Lactobacillus acidophilus NCFM hypothetical protein YP_194271.1 1404207 R 272621 CDS YP_194272.1 58337687 3252816 complement(1405010..1406287) 1 NC_006814.3 glycosyl transferase family protein 1406287 3252816 LBA1416 Lactobacillus acidophilus NCFM glycosyl transferase family protein YP_194272.1 1405010 R 272621 CDS YP_194273.1 58337688 3252820 complement(1406284..1406796) 1 NC_006814.3 hypothetical protein 1406796 3252820 LBA1417 Lactobacillus acidophilus NCFM hypothetical protein YP_194273.1 1406284 R 272621 CDS YP_194274.1 58337689 3252829 complement(1406954..1407874) 1 NC_006814.3 NADH-dependent oxidoreductase 1407874 3252829 LBA1418 Lactobacillus acidophilus NCFM NADH-dependent oxidoreductase YP_194274.1 1406954 R 272621 CDS YP_194275.1 58337690 3252830 1408156..1408302 1 NC_006814.3 hypothetical protein 1408302 3252830 LBA1419 Lactobacillus acidophilus NCFM hypothetical protein YP_194275.1 1408156 D 272621 CDS YP_194276.1 58337691 3253080 1408342..1409505 1 NC_006814.3 transposase 1409505 3253080 LBA1420 Lactobacillus acidophilus NCFM transposase YP_194276.1 1408342 D 272621 CDS YP_194277.1 58337692 3252872 complement(1409744..1409917) 1 NC_006814.3 COG1902 NADHflavin oxidoreductases, Old Yellow Enzyme family; NADH-dependent oxidoreductase 1409917 3252872 LBA1421 Lactobacillus acidophilus NCFM NADH-dependent oxidoreductase YP_194277.1 1409744 R 272621 CDS YP_194278.1 58337693 3252868 complement(1410032..1410586) 1 NC_006814.3 pyrazinamidase-nicotinamidase 1410586 pxnC 3252868 pxnC Lactobacillus acidophilus NCFM pyrazinamidase-nicotinamidase YP_194278.1 1410032 R 272621 CDS YP_194279.1 58337694 3252882 complement(1410679..1410813) 1 NC_006814.3 hypothetical protein 1410813 3252882 LBA1423 Lactobacillus acidophilus NCFM hypothetical protein YP_194279.1 1410679 R 272621 CDS YP_194280.1 58337695 3252901 complement(1410890..1412386) 1 NC_006814.3 COG0531 Amino acid transporters; amino acid permease 1412386 3252901 LBA1424 Lactobacillus acidophilus NCFM amino acid permease YP_194280.1 1410890 R 272621 CDS YP_194281.1 58337696 3252899 complement(1412518..1413213) 1 NC_006814.3 cell surface hydrolase; hypothetical protein 1413213 3252899 LBA1425 Lactobacillus acidophilus NCFM hypothetical protein YP_194281.1 1412518 R 272621 CDS YP_194282.1 58337697 3253090 complement(1413555..1414313) 1 NC_006814.3 hypothetical protein 1414313 3253090 LBA1426 Lactobacillus acidophilus NCFM hypothetical protein YP_194282.1 1413555 R 272621 CDS YP_194283.1 58337698 3252895 complement(1414413..1415105) 1 NC_006814.3 oxidoreductase 1415105 3252895 LBA1427 Lactobacillus acidophilus NCFM oxidoreductase YP_194283.1 1414413 R 272621 CDS YP_194284.1 58337699 3253091 complement(1415117..1415524) 1 NC_006814.3 hypothetical protein 1415524 3253091 LBA1428 Lactobacillus acidophilus NCFM hypothetical protein YP_194284.1 1415117 R 272621 CDS YP_194285.1 58337700 3253092 complement(1415542..1416720) 1 NC_006814.3 transporter-membrane protein 1416720 3253092 LBA1429 Lactobacillus acidophilus NCFM transporter-membrane protein YP_194285.1 1415542 R 272621 CDS YP_194286.1 58337701 3252905 complement(1416769..1418043) 1 NC_006814.3 histidine protein kinase 1418043 3252905 LBA1430 Lactobacillus acidophilus NCFM histidine protein kinase YP_194286.1 1416769 R 272621 CDS YP_194287.1 58337702 3252949 complement(1418053..1418718) 1 NC_006814.3 COG0745 Response regulators conserved isting of a CheY-like receiver domain and a winged-helix DNA-binding domain; two-component response regulator 1418718 3252949 LBA1431 Lactobacillus acidophilus NCFM two-component response regulator YP_194287.1 1418053 R 272621 CDS YP_194288.1 58337703 3252946 complement(1418726..1419340) 1 NC_006814.3 hypothetical protein 1419340 3252946 LBA1432 Lactobacillus acidophilus NCFM hypothetical protein YP_194288.1 1418726 R 272621 CDS YP_194289.1 58337704 3252939 1419565..1420560 1 NC_006814.3 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK 1420560 3252939 LBA1433 Lactobacillus acidophilus NCFM dihydroxyacetone kinase subunit DhaK YP_194289.1 1419565 D 272621 CDS YP_194290.1 58337705 3252937 1420573..1421157 1 NC_006814.3 dihydroxyacetone kinase 1421157 3252937 LBA1434 Lactobacillus acidophilus NCFM dihydroxyacetone kinase YP_194290.1 1420573 D 272621 CDS YP_194291.1 58337706 3252913 1421154..1421525 1 NC_006814.3 hypothetical protein 1421525 3252913 LBA1435 Lactobacillus acidophilus NCFM hypothetical protein YP_194291.1 1421154 D 272621 CDS YP_194292.1 58337707 3252917 1421543..1422250 1 NC_006814.3 GlpF; glycerol uptake facilitator protein 1422250 glpF 3252917 glpF Lactobacillus acidophilus NCFM glycerol uptake facilitator protein YP_194292.1 1421543 D 272621 CDS YP_194293.1 58337708 3252916 complement(1422499..1423941) 1 NC_006814.3 sucrose phosphorylase 1423941 3252916 LBA1437 Lactobacillus acidophilus NCFM sucrose phosphorylase YP_194293.1 1422499 R 272621 CDS YP_194294.1 58337709 3252915 complement(1423951..1426149) 1 NC_006814.3 alpha-galactosidase 1426149 melA 3252915 melA Lactobacillus acidophilus NCFM alpha-galactosidase YP_194294.1 1423951 R 272621 CDS YP_194295.1 58337710 3252934 complement(1426161..1427273) 1 NC_006814.3 MsmKII; ABC transporter nucleotide binding protein 1427273 3252934 LBA1439 Lactobacillus acidophilus NCFM ABC transporter nucleotide binding protein YP_194295.1 1426161 R 272621 CDS YP_194296.1 58337711 3252970 complement(1427305..1428138) 1 NC_006814.3 MsmGII; ABC transporter permease 1428138 3252970 LBA1440 Lactobacillus acidophilus NCFM ABC transporter permease YP_194296.1 1427305 R 272621 CDS YP_194297.1 58337712 3252966 complement(1428151..1429026) 1 NC_006814.3 MsmFII; ABC transporter permease 1429026 3252966 LBA1441 Lactobacillus acidophilus NCFM ABC transporter permease YP_194297.1 1428151 R 272621 CDS YP_194298.1 58337713 3252953 complement(1429040..1430296) 1 NC_006814.3 MsmEII; sugar ABC transporter substrate-binding protein 1430296 3252953 LBA1442 Lactobacillus acidophilus NCFM sugar ABC transporter substrate-binding protein YP_194298.1 1429040 R 272621 CDS YP_194299.1 58337714 3253014 1430540..1431379 1 NC_006814.3 MsmRII; msm operon regulatory protein 1431379 3253014 LBA1443 Lactobacillus acidophilus NCFM msm operon regulatory protein YP_194299.1 1430540 D 272621 CDS YP_194300.1 58337715 3253009 complement(1431437..1431871) 1 NC_006814.3 MerR; transcriptional regulator family protein 1431871 3253009 LBA1444 Lactobacillus acidophilus NCFM transcriptional regulator family protein YP_194300.1 1431437 R 272621 CDS YP_194301.1 58337716 3252999 1432032..1433504 1 NC_006814.3 multidrug resistance protein 1433504 3252999 LBA1446 Lactobacillus acidophilus NCFM multidrug resistance protein YP_194301.1 1432032 D 272621 CDS YP_194302.1 58337717 3253002 1433504..1434085 1 NC_006814.3 hypothetical protein 1434085 3253002 LBA1447 Lactobacillus acidophilus NCFM hypothetical protein YP_194302.1 1433504 D 272621 CDS YP_194303.1 58337718 3253008 complement(1434024..1434212) 1 NC_006814.3 alpha-galactosidase 1 (melibiase); alpha-galactosidase 1434212 3253008 LBA1448 Lactobacillus acidophilus NCFM alpha-galactosidase YP_194303.1 1434024 R 272621 CDS YP_194304.1 58337719 3252998 complement(1434317..1434631) 1 NC_006814.3 hypothetical protein 1434631 3252998 LBA1449 Lactobacillus acidophilus NCFM hypothetical protein YP_194304.1 1434317 R 272621 CDS YP_194305.1 58337720 3252982 complement(1434603..1434878) 1 NC_006814.3 hypothetical protein 1434878 3252982 LBA1450 Lactobacillus acidophilus NCFM hypothetical protein YP_194305.1 1434603 R 272621 CDS YP_194306.1 58337721 3252989 complement(1435001..1435681) 1 NC_006814.3 phage D3 terminase-like protein; hypothetical protein 1435681 3252989 LBA1452 Lactobacillus acidophilus NCFM hypothetical protein YP_194306.1 1435001 R 272621 CDS YP_194307.1 58337722 3252987 complement(1435904..1436146) 1 NC_006814.3 hypothetical protein 1436146 3252987 LBA1454 Lactobacillus acidophilus NCFM hypothetical protein YP_194307.1 1435904 R 272621 CDS YP_194308.1 58337723 3252997 complement(1436319..1437203) 1 NC_006814.3 N-acetylgalactosamine-4-sulfatase precursor; surface layer protein 1437203 3252997 LBA1455 Lactobacillus acidophilus NCFM surface layer protein YP_194308.1 1436319 R 272621 CDS YP_194309.1 58337724 3253030 complement(1437361..1438347) 1 NC_006814.3 mutarotase; galactose-1-epimerase 1438347 galM 3253030 galM Lactobacillus acidophilus NCFM galactose-1-epimerase YP_194309.1 1437361 R 272621 CDS YP_194310.1 58337725 3253041 complement(1438349..1439812) 1 NC_006814.3 catalyzes the formation of alpha-D-glucose 1-phosphate and UDP-galactose from UDP-glucose and alpha-D-galactose 1-phosphate in galactose metabolism; galactose-1-phosphate uridylyltransferase 1439812 galT 3253041 galT Lactobacillus acidophilus NCFM galactose-1-phosphate uridylyltransferase YP_194310.1 1438349 R 272621 CDS YP_194311.1 58337726 3253029 complement(1439832..1440995) 1 NC_006814.3 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 1440995 galK 3253029 galK Lactobacillus acidophilus NCFM galactokinase YP_194311.1 1439832 R 272621 CDS YP_194312.1 58337727 3253069 complement(1441212..1442231) 1 NC_006814.3 cell surface protein precursor; mucus binding protein 1442231 3253069 LBA1460 Lactobacillus acidophilus NCFM mucus binding protein YP_194312.1 1441212 R 272621 CDS YP_194313.1 58337728 3251246 complement(1442396..1443025) 1 NC_006814.3 regulator 1443025 3251246 LBA1461 Lactobacillus acidophilus NCFM regulator YP_194313.1 1442396 R 272621 CDS YP_194314.1 58337729 3251504 complement(1443147..1445150) 1 NC_006814.3 beta-D-galactosidase; beta-galactosidase 1445150 lacZ 3251504 lacZ Lactobacillus acidophilus NCFM beta-galactosidase YP_194314.1 1443147 R 272621 CDS YP_194315.1 58337730 3251415 complement(1445161..1447080) 1 NC_006814.3 lactose permease 1447080 lacS 3251415 lacS Lactobacillus acidophilus NCFM lactose permease YP_194315.1 1445161 R 272621 CDS YP_194316.1 58337731 3251180 complement(1447277..1448434) 1 NC_006814.3 is605tnpb family; transposase 1448434 3251180 LBA1464 Lactobacillus acidophilus NCFM transposase YP_194316.1 1447277 R 272621 CDS YP_194317.1 58337732 3251540 complement(1448787..1449794) 1 NC_006814.3 lactose transcriptional regulator; transcription repressor of beta-galactosidasegene 1449794 lacR 3251540 lacR Lactobacillus acidophilus NCFM transcription repressor of beta-galactosidasegene YP_194317.1 1448787 R 272621 CDS YP_194318.1 58337733 3251483 1450020..1451906 1 NC_006814.3 beta-galactosidase large subunit (lactase) 1451906 lacL 3251483 lacL Lactobacillus acidophilus NCFM beta-galactosidase large subunit (lactase) YP_194318.1 1450020 D 272621 CDS YP_194319.1 58337734 3251495 1451890..1452840 1 NC_006814.3 beta-galactosidase small subunit 1452840 lacM 3251495 lacM Lactobacillus acidophilus NCFM beta-galactosidase small subunit YP_194319.1 1451890 D 272621 CDS YP_194320.1 58337735 3251215 1452922..1453914 1 NC_006814.3 UDP-galactose 4-epimerase; udp-glucose 4-epimerase 1453914 galE 3251215 galE Lactobacillus acidophilus NCFM udp-glucose 4-epimerase YP_194320.1 1452922 D 272621 CDS YP_194321.1 58337736 3251471 complement(1454020..1455552) 1 NC_006814.3 hypothetical protein 1455552 3251471 LBA1470 Lactobacillus acidophilus NCFM hypothetical protein YP_194321.1 1454020 R 272621 CDS YP_194322.1 58337737 3251247 complement(1455570..1456793) 1 NC_006814.3 multidrug efflux permease 1456793 3251247 LBA1471 Lactobacillus acidophilus NCFM multidrug efflux permease YP_194322.1 1455570 R 272621 CDS YP_194323.1 58337738 3251214 1456970..1457929 1 NC_006814.3 Ribose operon repressor; ribose operon repressor 1457929 rbsR 3251214 rbsR Lactobacillus acidophilus NCFM ribose operon repressor YP_194323.1 1456970 D 272621 CDS YP_194324.1 58337739 3251470 complement(1457907..1460696) 1 NC_006814.3 alfa-L-rhamnosidase; alfa-l-rhamnosidase 1460696 3251470 LBA1473 Lactobacillus acidophilus NCFM alfa-l-rhamnosidase YP_194324.1 1457907 R 272621 CDS YP_194325.1 58337740 3251457 complement(1460705..1461049) 1 NC_006814.3 hypothetical protein 1461049 3251457 LBA1474 Lactobacillus acidophilus NCFM hypothetical protein YP_194325.1 1460705 R 272621 CDS YP_194326.1 58337741 3251496 1461091..1462332 1 NC_006814.3 transposase 1462332 3251496 LBA1475 Lactobacillus acidophilus NCFM transposase YP_194326.1 1461091 D 272621 CDS YP_194327.1 58337742 3251469 complement(1462502..1462948) 1 NC_006814.3 cellobiose phosphotransferase 1462948 3251469 LBA1476 Lactobacillus acidophilus NCFM cellobiose phosphotransferase YP_194327.1 1462502 R 272621 CDS YP_194328.1 58337743 3251485 complement(1463005..1463913) 1 NC_006814.3 sugar hydrolase 1463913 3251485 LBA1477 Lactobacillus acidophilus NCFM sugar hydrolase YP_194328.1 1463005 R 272621 CDS YP_194329.1 58337744 3251213 complement(1463916..1466120) 1 NC_006814.3 PTS systen transporter subunit IIABC 1466120 3251213 LBA1478 Lactobacillus acidophilus NCFM PTS systen transporter subunit IIABC YP_194329.1 1463916 R 272621 CDS YP_194330.1 58337745 3251413 complement(1466113..1466967) 1 NC_006814.3 transcriptional antiterminator LicT; beta-glucoside transcriptional antiterminator 1466967 licT 3251413 licT Lactobacillus acidophilus NCFM beta-glucoside transcriptional antiterminator YP_194330.1 1466113 R 272621 CDS YP_194331.1 58337746 3251474 complement(1467158..1468438) 1 NC_006814.3 beta-glucosidase 1468438 3251474 LBA1480 Lactobacillus acidophilus NCFM beta-glucosidase YP_194331.1 1467158 R 272621 CDS YP_194332.1 58337747 3251391 complement(1468571..1469557) 1 NC_006814.3 RbsB; D-ribose-binding protein 1469557 rbsB 3251391 rbsB Lactobacillus acidophilus NCFM D-ribose-binding protein YP_194332.1 1468571 R 272621 CDS YP_194333.1 58337748 3251479 complement(1469587..1470444) 1 NC_006814.3 RbsC; ribose ABC transporter 1470444 rbsC 3251479 rbsC Lactobacillus acidophilus NCFM ribose ABC transporter YP_194333.1 1469587 R 272621 CDS YP_194334.1 58337749 3251305 complement(1470552..1472030) 1 NC_006814.3 RbsA; ribose ABC transporter ATP binding protein 1472030 rbsA 3251305 rbsA Lactobacillus acidophilus NCFM ribose ABC transporter ATP binding protein YP_194334.1 1470552 R 272621 CDS YP_194335.1 58337750 3251184 complement(1472046..1472441) 1 NC_006814.3 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 1472441 rbsD 3251184 rbsD Lactobacillus acidophilus NCFM D-ribose pyranase YP_194335.1 1472046 R 272621 CDS YP_194336.1 58337751 3251205 complement(1472443..1473369) 1 NC_006814.3 RbsK; ribokinase 1473369 rbsK 3251205 rbsK Lactobacillus acidophilus NCFM ribokinase YP_194336.1 1472443 R 272621 CDS YP_194337.1 58337752 3251488 complement(1473607..1475052) 1 NC_006814.3 similar to hypothetical protein; L-fucose isomerase 1475052 3251488 LBA1486 Lactobacillus acidophilus NCFM L-fucose isomerase YP_194337.1 1473607 R 272621 CDS YP_194338.1 58337753 3251481 complement(1475249..1476406) 1 NC_006814.3 transposase, is605-tnpb 1476406 3251481 LBA1487 Lactobacillus acidophilus NCFM transposase, is605-tnpb YP_194338.1 1475249 R 272621 CDS YP_194339.1 58337754 3251503 complement(1476678..1477691) 1 NC_006814.3 RbsR; ribose operon repressor 1477691 rbsR 3251503 rbsR Lactobacillus acidophilus NCFM ribose operon repressor YP_194339.1 1476678 R 272621 CDS YP_194340.1 58337755 3251204 1477821..1478654 1 NC_006814.3 similar to transketolase; transketolase 1478654 3251204 LBA1489 Lactobacillus acidophilus NCFM transketolase YP_194340.1 1477821 D 272621 CDS YP_194341.1 58337756 3251499 1478647..1479588 1 NC_006814.3 similar to transketolase; transketolase 1479588 3251499 LBA1490 Lactobacillus acidophilus NCFM transketolase YP_194341.1 1478647 D 272621 CDS YP_194342.1 58337757 3251196 1479603..1481054 1 NC_006814.3 GlpK; glycerol kinase 1481054 glpK 3251196 glpK Lactobacillus acidophilus NCFM glycerol kinase YP_194342.1 1479603 D 272621 CDS YP_194343.1 58337758 3251343 1481085..1482293 1 NC_006814.3 AckB; acetate kinase 1482293 ackB 3251343 ackB Lactobacillus acidophilus NCFM acetate kinase YP_194343.1 1481085 D 272621 CDS YP_194344.1 58337759 3251393 complement(1482352..1483761) 1 NC_006814.3 LmrB; drug-export protein; lincomycin-resistance protein 1483761 lmrB 3251393 lmrB Lactobacillus acidophilus NCFM lincomycin-resistance protein YP_194344.1 1482352 R 272621 CDS YP_194345.1 58337760 3251238 1483972..1484766 1 NC_006814.3 bone protein protein; fibrinogen-binding protein 1484766 3251238 LBA1495 Lactobacillus acidophilus NCFM fibrinogen-binding protein YP_194345.1 1483972 D 272621 CDS YP_194346.1 58337761 3251498 1484754..1487729 1 NC_006814.3 cell surface protein precursor; fibrinogen-binding protein 1487729 3251498 LBA1496 Lactobacillus acidophilus NCFM fibrinogen-binding protein YP_194346.1 1484754 D 272621 CDS YP_194347.1 58337762 3251206 complement(1487831..1488841) 1 NC_006814.3 hypothetical protein 1488841 3251206 LBA1497 Lactobacillus acidophilus NCFM hypothetical protein YP_194347.1 1487831 R 272621 CDS YP_194348.1 58337763 3251210 complement(1488945..1489850) 1 NC_006814.3 ABC transporter 1489850 3251210 LBA1498 Lactobacillus acidophilus NCFM ABC transporter YP_194348.1 1488945 R 272621 CDS YP_194349.1 58337764 3251175 1490044..1490700 1 NC_006814.3 potential frameshift to 1500; ABC transporter 1490700 3251175 LBA1499 Lactobacillus acidophilus NCFM ABC transporter YP_194349.1 1490044 D 272621 CDS YP_194350.1 58337765 3251176 1490681..1491445 1 NC_006814.3 potential frameshift to 1499; ABC transporter 1491445 3251176 LBA1500 Lactobacillus acidophilus NCFM ABC transporter YP_194350.1 1490681 D 272621 CDS YP_194351.1 58337766 3251394 complement(1491498..1492835) 1 NC_006814.3 GlnA; COG0174 Glutamine synthetase; glutamine synthetase 1492835 glnA 3251394 glnA Lactobacillus acidophilus NCFM glutamine synthetase YP_194351.1 1491498 R 272621 CDS YP_194352.1 58337767 3251484 complement(1492973..1494223) 1 NC_006814.3 aluminum resistance protein 1494223 3251484 LBA1502 Lactobacillus acidophilus NCFM aluminum resistance protein YP_194352.1 1492973 R 272621 CDS YP_194353.1 58337768 3251419 complement(1494216..1495136) 1 NC_006814.3 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 1495136 miaA 3251419 miaA Lactobacillus acidophilus NCFM tRNA delta(2)-isopentenylpyrophosphate transferase YP_194353.1 1494216 R 272621 CDS YP_194354.1 58337769 3251195 complement(1495208..1495609) 1 NC_006814.3 COG0607 Rhodanese-related sulfurtransferase; rhodanese-related sulfurtransferase 1495609 3251195 LBA1504 Lactobacillus acidophilus NCFM rhodanese-related sulfurtransferase YP_194354.1 1495208 R 272621 CDS YP_194355.1 58337770 3251417 complement(1495668..1495886) 1 NC_006814.3 hypothetical protein 1495886 3251417 LBA1505 Lactobacillus acidophilus NCFM hypothetical protein YP_194355.1 1495668 R 272621 CDS YP_194356.1 58337771 3251418 complement(1495886..1496566) 1 NC_006814.3 hypothetical protein 1496566 3251418 LBA1506 Lactobacillus acidophilus NCFM hypothetical protein YP_194356.1 1495886 R 272621 CDS YP_194357.1 58337772 3251543 complement(1496601..1497164) 1 NC_006814.3 COG0212 5-formyltetrahydrofolate cyclo-ligase; 5-formyltetrahydrofolate cyclo-ligase 1497164 3251543 LBA1507 Lactobacillus acidophilus NCFM 5-formyltetrahydrofolate cyclo-ligase YP_194357.1 1496601 R 272621 CDS YP_194358.1 58337773 3251468 complement(1497218..1497367) 1 NC_006814.3 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 1497367 rpmG 3251468 rpmG Lactobacillus acidophilus NCFM 50S ribosomal protein L33 YP_194358.1 1497218 R 272621 CDS YP_194359.1 58337774 3251216 complement(1497444..1499552) 1 NC_006814.3 penicillin-binding protein 1499552 3251216 LBA1509 Lactobacillus acidophilus NCFM penicillin-binding protein YP_194359.1 1497444 R 272621 CDS YP_194360.1 58337775 3251467 1499643..1502222 1 NC_006814.3 ABC transporter permease 1502222 3251467 LBA1510 Lactobacillus acidophilus NCFM ABC transporter permease YP_194360.1 1499643 D 272621 CDS YP_194361.1 58337776 3251313 1502338..1503261 1 NC_006814.3 COG2971 Predicted N-acetylglucosamine kinase; N-acetylglucosamine kinase 1503261 3251313 LBA1511 Lactobacillus acidophilus NCFM N-acetylglucosamine kinase YP_194361.1 1502338 D 272621 CDS YP_194362.1 58337777 3251212 complement(1503341..1508224) 1 NC_006814.3 cell envelope-associated protein PrtR; PrtP 1508224 3251212 LBA1512 Lactobacillus acidophilus NCFM PrtP YP_194362.1 1503341 R 272621 CDS YP_194363.1 58337778 3251211 complement(1508687..1509013) 1 NC_006814.3 potential frameshift to 1514; COG4292 Predicted membrane protein; low temperature requirement A protein 1509013 3251211 LBA1513 Lactobacillus acidophilus NCFM low temperature requirement A protein YP_194363.1 1508687 R 272621 CDS YP_194364.1 58337779 3251208 complement(1509236..1509373) 1 NC_006814.3 potential frameshift to 1513; COG4292 Predicted membrane protein; low temperature requirement A protein 1509373 3251208 LBA1514 Lactobacillus acidophilus NCFM low temperature requirement A protein YP_194364.1 1509236 R 272621 CDS YP_194365.1 58337780 3251209 complement(1509394..1510677) 1 NC_006814.3 catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 1510677 pepT 3251209 pepT Lactobacillus acidophilus NCFM peptidase T YP_194365.1 1509394 R 272621 CDS YP_194366.1 58337781 3251342 complement(1510792..1511706) 1 NC_006814.3 COG0039 Malate-lactate dehydrogenases; L-LDH 1511706 3251342 LBA1516 Lactobacillus acidophilus NCFM L-LDH YP_194366.1 1510792 R 272621 CDS YP_194367.1 58337782 3251472 complement(1511767..1512243) 1 NC_006814.3 GreA; transcriptional elongation factor 1512243 greA 3251472 greA Lactobacillus acidophilus NCFM transcriptional elongation factor YP_194367.1 1511767 R 272621 CDS YP_194368.1 58337783 3251477 complement(1512319..1514733) 1 NC_006814.3 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 1514733 pheT 3251477 pheT Lactobacillus acidophilus NCFM phenylalanyl-tRNA synthetase subunit beta YP_194368.1 1512319 R 272621 CDS YP_194369.1 58337784 3251492 complement(1514737..1515786) 1 NC_006814.3 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 1515786 pheS 3251492 pheS Lactobacillus acidophilus NCFM phenylalanyl-tRNA synthetase subunit alpha YP_194369.1 1514737 R 272621 CDS YP_194370.1 58337785 3251476 complement(1516069..1516419) 1 NC_006814.3 COG1733 Predicted transcriptional regulators; transcriptional regulator 1516419 3251476 LBA1520 Lactobacillus acidophilus NCFM transcriptional regulator YP_194370.1 1516069 R 272621 CDS YP_194371.1 58337786 3251501 complement(1516522..1517289) 1 NC_006814.3 COG0566 rRNA methylases; rRNA methylase 1517289 3251501 LBA1521 Lactobacillus acidophilus NCFM rRNA methylase YP_194371.1 1516522 R 272621 CDS YP_194372.1 58337787 3251541 1517415..1517687 1 NC_006814.3 AcyP; COG1254 Acylphosphatases; acylphosphatase 1517687 acyP 3251541 acyP Lactobacillus acidophilus NCFM acylphosphatase YP_194372.1 1517415 D 272621 CDS YP_194373.1 58337788 3251414 1517729..1518697 1 NC_006814.3 SpoIIIJ; family protein 1518697 3251414 LBA1523 Lactobacillus acidophilus NCFM family protein YP_194373.1 1517729 D 272621 CDS YP_194374.1 58337789 3251506 complement(1518733..1520310) 1 NC_006814.3 two-component sensor histidine kinase 1520310 lisK 3251506 lisK Lactobacillus acidophilus NCFM two-component sensor histidine kinase YP_194374.1 1518733 R 272621 CDS YP_194375.1 58337790 3251505 complement(1520288..1521004) 1 NC_006814.3 COG0745 Response regulators conserved isting of a CheY-like receiver domain and a winged-helix DNA-binding domain; two-component system regulator 1521004 lisR 3251505 lisR Lactobacillus acidophilus NCFM two-component system regulator YP_194375.1 1520288 R 272621 CDS YP_194376.1 58337791 3251473 complement(1521168..1521716) 1 NC_006814.3 hypothetical protein 1521716 3251473 LBA1526 Lactobacillus acidophilus NCFM hypothetical protein YP_194376.1 1521168 R 272621 CDS YP_194377.1 58337792 3251497 complement(1521718..1522869) 1 NC_006814.3 COG1323 Predicted nucleotidyltransferase; hypothetical protein 1522869 3251497 LBA1527 Lactobacillus acidophilus NCFM hypothetical protein YP_194377.1 1521718 R 272621 CDS YP_194378.1 58337793 3251179 complement(1522876..1523223) 1 NC_006814.3 hypothetical protein 1523223 3251179 LBA1528 Lactobacillus acidophilus NCFM hypothetical protein YP_194378.1 1522876 R 272621 CDS YP_194379.1 58337794 3251178 complement(1523238..1523837) 1 NC_006814.3 hypothetical protein 1523837 3251178 LBA1529 Lactobacillus acidophilus NCFM hypothetical protein YP_194379.1 1523238 R 272621 CDS YP_194380.1 58337795 3251401 complement(1523818..1524474) 1 NC_006814.3 NadD; nicotinate-nucleotide adenyltransferase 1524474 nadD 3251401 nadD Lactobacillus acidophilus NCFM nicotinate-nucleotide adenyltransferase YP_194380.1 1523818 R 272621 CDS YP_194381.1 58337796 3251344 complement(1524485..1525594) 1 NC_006814.3 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis; GTP-binding protein YqeH 1525594 3251344 LBA1531 Lactobacillus acidophilus NCFM GTP-binding protein YqeH YP_194381.1 1524485 R 272621 CDS YP_194382.1 58337797 3251177 complement(1525587..1526111) 1 NC_006814.3 hypothetical protein 1526111 3251177 LBA1532 Lactobacillus acidophilus NCFM hypothetical protein YP_194382.1 1525587 R 272621 CDS YP_194385.1 58337800 3251237 1527704..1528705 1 NC_006814.3 catalyzes the formation of inosine from adenosine; adenosine deaminase 1528705 3251237 LBA1535 Lactobacillus acidophilus NCFM adenosine deaminase YP_194385.1 1527704 D 272621 CDS YP_194386.1 58337801 3251516 complement(1528755..1529111) 1 NC_006814.3 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 1529111 rplT 3251516 rplT Lactobacillus acidophilus NCFM 50S ribosomal protein L20 YP_194386.1 1528755 R 272621 CDS YP_194387.1 58337802 3251517 complement(1529153..1529353) 1 NC_006814.3 50S ribosomal protein L35 1529353 rpmI 3251517 rpmI Lactobacillus acidophilus NCFM 50S ribosomal protein L35 YP_194387.1 1529153 R 272621 CDS YP_194388.1 58337803 3251390 complement(1529375..1529827) 1 NC_006814.3 translation initiation factor IF-3; translational initiation factor IF3 1529827 infC 3251390 infC Lactobacillus acidophilus NCFM translational initiation factor IF3 YP_194388.1 1529375 R 272621 CDS YP_194389.1 58337804 3251550 complement(1530119..1530634) 1 NC_006814.3 hypothetical protein 1530634 3251550 LBA1539 Lactobacillus acidophilus NCFM hypothetical protein YP_194389.1 1530119 R 272621 CDS YP_194390.1 58337805 3251551 complement(1530776..1531201) 1 NC_006814.3 hypothetical protein 1531201 3251551 LBA1541 Lactobacillus acidophilus NCFM hypothetical protein YP_194390.1 1530776 R 272621 CDS YP_194391.1 58337806 3251256 complement(1531198..1531632) 1 NC_006814.3 hypothetical protein 1531632 3251256 LBA1542 Lactobacillus acidophilus NCFM hypothetical protein YP_194391.1 1531198 R 272621 CDS YP_194392.1 58337807 3251306 complement(1531790..1533724) 1 NC_006814.3 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 1533724 thrS 3251306 thrS Lactobacillus acidophilus NCFM threonyl-tRNA synthetase YP_194392.1 1531790 R 272621 CDS YP_194393.1 58337808 3251255 complement(1534005..1534913) 1 NC_006814.3 Primosomal protein that may act to load helicase DnaC during DNA replication; primosomal protein DnaI 1534913 dnaI 3251255 dnaI Lactobacillus acidophilus NCFM primosomal protein DnaI YP_194393.1 1534005 R 272621 CDS YP_194394.1 58337809 3251509 complement(1534923..1536263) 1 NC_006814.3 DnaB; chromosome replication initiation 1536263 dnaB 3251509 dnaB Lactobacillus acidophilus NCFM chromosome replication initiation YP_194394.1 1534923 R 272621 CDS YP_194395.1 58337810 3251491 complement(1536266..1536733) 1 NC_006814.3 transcriptional regulator NrdR 1536733 nrdR 3251491 nrdR Lactobacillus acidophilus NCFM transcriptional regulator NrdR YP_194395.1 1536266 R 272621 CDS YP_194396.1 58337811 3251490 complement(1536736..1537338) 1 NC_006814.3 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 1537338 coaE 3251490 coaE Lactobacillus acidophilus NCFM dephospho-CoA kinase YP_194396.1 1536736 R 272621 CDS YP_194397.1 58337812 3251489 complement(1537335..1538165) 1 NC_006814.3 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 1538165 mutM 3251489 mutM Lactobacillus acidophilus NCFM formamidopyrimidine-DNA glycosylase YP_194397.1 1537335 R 272621 CDS YP_194398.1 58337813 3251511 complement(1538174..1540834) 1 NC_006814.3 DpoI; DNA polymerase I 1540834 polA 3251511 polA Lactobacillus acidophilus NCFM DNA polymerase I YP_194398.1 1538174 R 272621 CDS YP_194399.1 58337814 3251510 complement(1543233..1544504) 1 NC_006814.3 PurD; phosphoribosylamine--glycine ligase 1544504 purD 3251510 purD Lactobacillus acidophilus NCFM phosphoribosylamine--glycine ligase YP_194399.1 1543233 R 272621 CDS YP_194400.1 58337815 3251379 complement(1544517..1546058) 1 NC_006814.3 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 1546058 purH 3251379 purH Lactobacillus acidophilus NCFM bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_194400.1 1544517 R 272621 CDS YP_194401.1 58337816 3251378 complement(1546055..1546657) 1 NC_006814.3 PurN; phosphoribosyl glycinamide formyltransferase 1546657 purN 3251378 purN Lactobacillus acidophilus NCFM phosphoribosyl glycinamide formyltransferase YP_194401.1 1546055 R 272621 CDS YP_194402.1 58337817 3251376 complement(1546667..1547704) 1 NC_006814.3 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 1547704 purM 3251376 purM Lactobacillus acidophilus NCFM phosphoribosylaminoimidazole synthetase YP_194402.1 1546667 R 272621 CDS YP_194403.1 58337818 3251374 complement(1547707..1549173) 1 NC_006814.3 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 1549173 purL 3251374 purL Lactobacillus acidophilus NCFM amidophosphoribosyltransferase YP_194403.1 1547707 R 272621 CDS YP_194404.1 58337819 3251375 complement(1549131..1551359) 1 NC_006814.3 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase II 1551359 purL 3251375 purL Lactobacillus acidophilus NCFM phosphoribosylformylglycinamidine synthase II YP_194404.1 1549131 R 272621 CDS YP_194405.1 58337820 3251377 complement(1551356..1552027) 1 NC_006814.3 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase I 1552027 purQ 3251377 purQ Lactobacillus acidophilus NCFM phosphoribosylformylglycinamidine synthase I YP_194405.1 1551356 R 272621 CDS YP_194406.1 58337821 3251373 complement(1552024..1552278) 1 NC_006814.3 PurS; hypothetical protein; phosphoribosylformylglycinamidine (FGAM) synthase 1552278 purS 3251373 purS Lactobacillus acidophilus NCFM phosphoribosylformylglycinamidine (FGAM) synthase YP_194406.1 1552024 R 272621 CDS YP_194407.1 58337822 3251515 complement(1552279..1552995) 1 NC_006814.3 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazolesuccinocarboxamide synthase 1552995 purC 3251515 purC Lactobacillus acidophilus NCFM phosphoribosylaminoimidazolesuccinocarboxamide synthase YP_194407.1 1552279 R 272621 CDS YP_194408.1 58337823 3251372 complement(1553200..1554279) 1 NC_006814.3 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 1554279 purK 3251372 purK Lactobacillus acidophilus NCFM phosphoribosylaminoimidazole carboxylase ATPase subunit YP_194408.1 1553200 R 272621 CDS YP_194409.1 58337824 3251187 complement(1554341..1554826) 1 NC_006814.3 PurE; phosphoribosylaminoimidazole carboxylase I; phosphoribosylaminoimidazole carboxylase 1554826 purE 3251187 purE Lactobacillus acidophilus NCFM phosphoribosylaminoimidazole carboxylase YP_194409.1 1554341 R 272621 CDS YP_194410.1 58337825 3251186 complement(1554844..1556505) 1 NC_006814.3 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase 1556505 3251186 LBA1562 Lactobacillus acidophilus NCFM formate--tetrahydrofolate ligase YP_194410.1 1554844 R 272621 CDS YP_194411.1 58337826 3251185 complement(1556692..1557366) 1 NC_006814.3 COG0716 Flavodoxins; flavodoxin 1557366 3251185 LBA1563 Lactobacillus acidophilus NCFM flavodoxin YP_194411.1 1556692 R 272621 CDS YP_194412.1 58337827 3251552 complement(1557513..1558394) 1 NC_006814.3 hypothetical protein 1558394 3251552 LBA1564 Lactobacillus acidophilus NCFM hypothetical protein YP_194412.1 1557513 R 272621 CDS YP_194413.1 58337828 3251197 complement(1558412..1558720) 1 NC_006814.3 COG3077 DNA-damage-inducible protein J; DNA-damage-inducible protein J 1558720 3251197 LBA1565 Lactobacillus acidophilus NCFM DNA-damage-inducible protein J YP_194413.1 1558412 R 272621 CDS YP_194414.1 58337829 3251538 complement(1558847..1559824) 1 NC_006814.3 bacteriocin helveticin J 1559824 3251538 LBA1566 Lactobacillus acidophilus NCFM bacteriocin helveticin J YP_194414.1 1558847 R 272621 CDS YP_194415.1 58337830 3251537 1559967..1561484 1 NC_006814.3 Aminopeptidase N; aminopeptidase 1561484 3251537 LBA1567 Lactobacillus acidophilus NCFM aminopeptidase YP_194415.1 1559967 D 272621 CDS YP_194416.1 58337831 3251198 1561505..1562566 1 NC_006814.3 surface protein 1562566 3251198 LBA1568 Lactobacillus acidophilus NCFM surface protein YP_194416.1 1561505 D 272621 CDS YP_194419.1 58337834 3251202 1564186..1565520 1 NC_006814.3 cation efflux protein; membrane protein 1565520 3251202 LBA1571 Lactobacillus acidophilus NCFM membrane protein YP_194419.1 1564186 D 272621 CDS YP_194420.1 58337835 3251201 complement(1565616..1566488) 1 NC_006814.3 arginase 1566488 3251201 LBA1572 Lactobacillus acidophilus NCFM arginase YP_194420.1 1565616 R 272621 CDS YP_194421.1 58337836 3251429 complement(1566514..1567152) 1 NC_006814.3 COG2364 Predicted membrane protein; hypothetical protein 1567152 3251429 LBA1573 Lactobacillus acidophilus NCFM hypothetical protein YP_194421.1 1566514 R 272621 CDS YP_194422.1 58337837 3251428 complement(1567115..1568557) 1 NC_006814.3 BglH; similar to phospho-beta-glucosidase; beta-glucosidase 1568557 bglH 3251428 bglH Lactobacillus acidophilus NCFM beta-glucosidase YP_194422.1 1567115 R 272621 CDS YP_194423.1 58337838 3251427 complement(1568559..1570241) 1 NC_006814.3 potential frameshift to 1576; beta-glucoside-specific enzyme II 1570241 3251427 LBA1575 Lactobacillus acidophilus NCFM beta-glucoside-specific enzyme II YP_194423.1 1568559 R 272621 CDS YP_194424.1 58337839 3251426 complement(1570231..1570434) 1 NC_006814.3 potential frameshift to 1575; phosphotransferase system (PTS) beta-glucoside-specific enzyme; beta-glucoside-specific enzyme II 1570434 3251426 LBA1576 Lactobacillus acidophilus NCFM beta-glucoside-specific enzyme II YP_194424.1 1570231 R 272621 CDS YP_194425.1 58337840 3251522 complement(1570615..1571448) 1 NC_006814.3 transcriptional regulator 1571448 3251522 LBA1577 Lactobacillus acidophilus NCFM transcriptional regulator YP_194425.1 1570615 R 272621 CDS YP_194426.1 58337841 3251521 complement(1571570..1573654) 1 NC_006814.3 integral membrane protein; serine protease 1573654 3251521 LBA1578 Lactobacillus acidophilus NCFM serine protease YP_194426.1 1571570 R 272621 CDS YP_194427.1 58337842 3251519 complement(1573756..1575069) 1 NC_006814.3 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 1575069 murC 3251519 murC Lactobacillus acidophilus NCFM UDP-N-acetylmuramate--L-alanine ligase YP_194427.1 1573756 R 272621 CDS YP_194428.1 58337843 3251520 complement(1575171..1575818) 1 NC_006814.3 PheT; COG0073 EMAP domain; phenylalanyl-tRNA synthetase subunit beta 1575818 pheT 3251520 pheT Lactobacillus acidophilus NCFM phenylalanyl-tRNA synthetase subunit beta YP_194428.1 1575171 R 272621 CDS YP_194429.1 58337844 3251518 complement(1575838..1576158) 1 NC_006814.3 thioredoxin 1576158 3251518 LBA1581 Lactobacillus acidophilus NCFM thioredoxin YP_194429.1 1575838 R 272621 CDS YP_194430.1 58337845 3251544 complement(1576224..1576880) 1 NC_006814.3 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 1576880 trmB 3251544 trmB Lactobacillus acidophilus NCFM tRNA (guanine-N(7)-)-methyltransferase YP_194430.1 1576224 R 272621 CDS YP_194431.1 58337846 3251523 complement(1576890..1578101) 1 NC_006814.3 ABC transporter permease 1578101 3251523 LBA1584 Lactobacillus acidophilus NCFM ABC transporter permease YP_194431.1 1576890 R 272621 CDS YP_194432.1 58337847 3251524 complement(1578088..1578831) 1 NC_006814.3 ABC transporter ATP-binding protein 1578831 3251524 LBA1585 Lactobacillus acidophilus NCFM ABC transporter ATP-binding protein YP_194432.1 1578088 R 272621 CDS YP_194433.1 58337848 3251549 1578925..1579356 1 NC_006814.3 histidine triad HIT family protein 1579356 3251549 LBA1586 Lactobacillus acidophilus NCFM histidine triad HIT family protein YP_194433.1 1578925 D 272621 CDS YP_194434.1 58337849 3251548 1579368..1579703 1 NC_006814.3 hypothetical protein FLJ25124; tropomyosin 1579703 3251548 LBA1587 Lactobacillus acidophilus NCFM tropomyosin YP_194434.1 1579368 D 272621 CDS YP_194435.1 58337850 3251227 1579821..1580723 1 NC_006814.3 cis/trans isomerase of peptidylprolyl; PPIase; membrane-bound lipoprotein; peptidyl-prolyl isomerase 1580723 prsA 3251227 prsA Lactobacillus acidophilus NCFM peptidyl-prolyl isomerase YP_194435.1 1579821 D 272621 CDS YP_194436.1 58337851 3251225 complement(1580793..1581770) 1 NC_006814.3 COG3481 Predicted family hydrolase; CMP-binding factor 1581770 3251225 LBA1589 Lactobacillus acidophilus NCFM CMP-binding factor YP_194436.1 1580793 R 272621 CDS YP_194437.1 58337852 3251226 complement(1581763..1584261) 1 NC_006814.3 COG4717 Uncharacterized conserved protein; hypothetical protein 1584261 3251226 LBA1590 Lactobacillus acidophilus NCFM hypothetical protein YP_194437.1 1581763 R 272621 CDS YP_194438.1 58337853 3251229 complement(1584242..1585453) 1 NC_006814.3 COG0420 DNA repair exonuclease; phosphoesterase 1585453 3251229 LBA1591 Lactobacillus acidophilus NCFM phosphoesterase YP_194438.1 1584242 R 272621 CDS YP_194439.1 58337854 3251230 complement(1585462..1585812) 1 NC_006814.3 COG3679 Uncharacterized conserved protein; hypothetical protein 1585812 3251230 LBA1592 Lactobacillus acidophilus NCFM hypothetical protein YP_194439.1 1585462 R 272621 CDS YP_194440.1 58337855 3251307 complement(1585828..1587885) 1 NC_006814.3 penicillin-binding protein 1587885 pbpF 3251307 pbpF Lactobacillus acidophilus NCFM penicillin-binding protein YP_194440.1 1585828 R 272621 CDS YP_194441.1 58337856 3251311 1587975..1588820 1 NC_006814.3 ribosomal large subunit pseudouridine synthase 1588820 3251311 LBA1594 Lactobacillus acidophilus NCFM ribosomal large subunit pseudouridine synthase YP_194441.1 1587975 D 272621 CDS YP_194442.1 58337857 3251310 1588954..1589706 1 NC_006814.3 GlpF; glycerol uptake facilitator protein 1589706 glpF 3251310 glpF Lactobacillus acidophilus NCFM glycerol uptake facilitator protein YP_194442.1 1588954 D 272621 CDS YP_194443.1 58337858 3251219 1589864..1590544 1 NC_006814.3 hypothetical protein 1590544 3251219 LBA1597 Lactobacillus acidophilus NCFM hypothetical protein YP_194443.1 1589864 D 272621 CDS YP_194444.1 58337859 3251312 complement(1590585..1591607) 1 NC_006814.3 L-lactate dehydrogenase, cytochrome-type (lldD); glycolate oxidase 1591607 3251312 LBA1598 Lactobacillus acidophilus NCFM glycolate oxidase YP_194444.1 1590585 R 272621 CDS YP_194445.1 58337860 3251224 complement(1591738..1592649) 1 NC_006814.3 COG0191 Fructose-tagatose bisphosphate aldolase; fructose-bisphosphate aldolase 1592649 fbaA 3251224 fbaA Lactobacillus acidophilus NCFM fructose-bisphosphate aldolase YP_194445.1 1591738 R 272621 CDS YP_194446.1 58337861 3251223 complement(1592758..1594443) 1 NC_006814.3 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 1594443 argS 3251223 argS Lactobacillus acidophilus NCFM arginyl-tRNA synthetase YP_194446.1 1592758 R 272621 CDS YP_194447.1 58337862 3251452 complement(1594716..1595405) 1 NC_006814.3 cell surface protein 1595405 3251452 LBA1601 Lactobacillus acidophilus NCFM cell surface protein YP_194447.1 1594716 R 272621 CDS YP_194448.1 58337863 3251455 complement(1595505..1596353) 1 NC_006814.3 COG0063 Predicted sugar kinase; P-loop ATPase superfamily sugar kinase 1596353 3251455 LBA1602 Lactobacillus acidophilus NCFM P-loop ATPase superfamily sugar kinase YP_194448.1 1595505 R 272621 CDS YP_194449.1 58337864 3251454 complement(1596356..1597654) 1 NC_006814.3 serine-type D-Ala-D-Ala carboxypeptidase; d-alanyl-d-alanine carboxypeptidase 1597654 vanY 3251454 vanY Lactobacillus acidophilus NCFM d-alanyl-d-alanine carboxypeptidase YP_194449.1 1596356 R 272621 CDS YP_194450.1 58337865 3251193 1597914..1598243 1 NC_006814.3 hypothetical protein 1598243 3251193 LBA1604 Lactobacillus acidophilus NCFM hypothetical protein YP_194450.1 1597914 D 272621 CDS YP_194451.1 58337866 3251192 complement(1598295..1599326) 1 NC_006814.3 penicillin-binding protein 1599326 pbpX 3251192 pbpX Lactobacillus acidophilus NCFM penicillin-binding protein YP_194451.1 1598295 R 272621 CDS YP_194452.1 58337867 3251194 complement(1599383..1599733) 1 NC_006814.3 integral membrane protein; hypothetical protein 1599733 3251194 LBA1606 Lactobacillus acidophilus NCFM hypothetical protein YP_194452.1 1599383 R 272621 CDS YP_194453.1 58337868 3251347 complement(1599787..1601076) 1 NC_006814.3 phosphatidylserine decarboxylase 1601076 3251347 LBA1607 Lactobacillus acidophilus NCFM phosphatidylserine decarboxylase YP_194453.1 1599787 R 272621 CDS YP_194454.1 58337869 3251348 complement(1601137..1601394) 1 NC_006814.3 hypothetical protein 1601394 3251348 LBA1608 Lactobacillus acidophilus NCFM hypothetical protein YP_194454.1 1601137 R 272621 CDS YP_194455.1 58337870 3251402 complement(1601504..1603435) 1 NC_006814.3 mucus binding protein 1603435 3251402 LBA1609 Lactobacillus acidophilus NCFM mucus binding protein YP_194455.1 1601504 R 272621 CDS YP_194456.1 58337871 3251272 complement(1603630..1604043) 1 NC_006814.3 4-carboxymuconolactone decarboxylase; hypothetical protein 1604043 3251272 LBA1610 Lactobacillus acidophilus NCFM hypothetical protein YP_194456.1 1603630 R 272621 CDS YP_194457.1 58337872 3251268 complement(1604586..1612205) 1 NC_006814.3 FmtB; FmtB protein; surface protein 1612205 fmtB 3251268 fmtB Lactobacillus acidophilus NCFM surface protein YP_194457.1 1604586 R 272621 CDS YP_194458.1 58337873 3251269 complement(1612418..1615138) 1 NC_006814.3 fibrinogen-binding protein 1615138 3251269 LBA1612 Lactobacillus acidophilus NCFM fibrinogen-binding protein YP_194458.1 1612418 R 272621 CDS YP_194459.1 58337874 3251271 complement(1615464..1615691) 1 NC_006814.3 hypothetical protein 1615691 3251271 LBA1613 Lactobacillus acidophilus NCFM hypothetical protein YP_194459.1 1615464 R 272621 CDS YP_194460.1 58337875 3251404 complement(1615692..1616108) 1 NC_006814.3 transcriptional regulator 1616108 3251404 LBA1614 Lactobacillus acidophilus NCFM transcriptional regulator YP_194460.1 1615692 R 272621 CDS YP_194461.1 58337876 3251403 complement(1616846..1618492) 1 NC_006814.3 polysaccharide transporter 1618492 3251403 LBA1616 Lactobacillus acidophilus NCFM polysaccharide transporter YP_194461.1 1616846 R 272621 CDS YP_194462.1 58337877 3251380 complement(1618587..1621001) 1 NC_006814.3 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 1621001 leuS 3251380 leuS Lactobacillus acidophilus NCFM leucyl-tRNA synthetase YP_194462.1 1618587 R 272621 CDS YP_194463.1 58337878 3251382 1621292..1621951 1 NC_006814.3 COG0671 Membrane-associated phospholipid phosphatase; hypothetical protein 1621951 3251382 LBA1618 Lactobacillus acidophilus NCFM hypothetical protein YP_194463.1 1621292 D 272621 CDS YP_194464.1 58337879 3251381 complement(1621989..1622489) 1 NC_006814.3 potential frameshift to 1620; oxidoreductase, pyridine nucleotide-disulfide family; NADH dehydrogenase 1622489 3251381 LBA1619 Lactobacillus acidophilus NCFM NADH dehydrogenase YP_194464.1 1621989 R 272621 CDS YP_194465.1 58337880 3251330 complement(1622542..1623195) 1 NC_006814.3 potential frameshift to 1619; NADH dehydrogenase 1623195 3251330 LBA1620 Lactobacillus acidophilus NCFM NADH dehydrogenase YP_194465.1 1622542 R 272621 CDS YP_194466.1 58337881 3251384 complement(1623770..1625227) 1 NC_006814.3 multidrug transporter 1625227 3251384 LBA1621 Lactobacillus acidophilus NCFM multidrug transporter YP_194466.1 1623770 R 272621 CDS YP_194467.1 58337882 3251331 complement(1625250..1626449) 1 NC_006814.3 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 1626449 metK 3251331 metK Lactobacillus acidophilus NCFM S-adenosylmethionine synthetase YP_194467.1 1625250 R 272621 CDS YP_194468.1 58337883 3251281 complement(1627192..1627344) 1 NC_006814.3 potential frameshift to 1624; transporter 1627344 3251281 LBA1623 Lactobacillus acidophilus NCFM transporter YP_194468.1 1627192 R 272621 CDS YP_194469.1 58337884 3251280 complement(1627314..1627451) 1 NC_006814.3 potential frameshift to 1623; transporter 1627451 3251280 LBA1624 Lactobacillus acidophilus NCFM transporter YP_194469.1 1627314 R 272621 CDS YP_194470.1 58337885 3251289 complement(1634900..1636207) 1 NC_006814.3 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 1636207 3251289 LBA1626 Lactobacillus acidophilus NCFM seryl-tRNA synthetase YP_194470.1 1634900 R 272621 CDS YP_194471.1 58337886 3251290 complement(1636434..1636985) 1 NC_006814.3 ribosomal-protein-alanine N-acetyltransferase 1636985 3251290 LBA1627 Lactobacillus acidophilus NCFM ribosomal-protein-alanine N-acetyltransferase YP_194471.1 1636434 R 272621 CDS YP_194472.1 58337887 3251458 complement(1636985..1637593) 1 NC_006814.3 COG0398 Uncharacterized conserved protein; hypothetical protein 1637593 3251458 LBA1628 Lactobacillus acidophilus NCFM hypothetical protein YP_194472.1 1636985 R 272621 CDS YP_194473.1 58337888 3251463 1637755..1638549 1 NC_006814.3 COG0657 Esterase-lipase; esterase 1638549 3251463 LBA1629 Lactobacillus acidophilus NCFM esterase YP_194473.1 1637755 D 272621 CDS YP_194474.1 58337889 3251461 1638552..1639409 1 NC_006814.3 PlcR; hypothetical protein; regulator 1639409 plcR 3251461 plcR Lactobacillus acidophilus NCFM regulator YP_194474.1 1638552 D 272621 CDS YP_194475.1 58337890 3251462 complement(1639447..1639950) 1 NC_006814.3 purine trans deoxyribosylase; deoxyribosyltransferase 1639950 3251462 LBA1631 Lactobacillus acidophilus NCFM deoxyribosyltransferase YP_194475.1 1639447 R 272621 CDS YP_194476.1 58337891 3251449 1640119..1641501 1 NC_006814.3 SsdH; COG1012 NAD-dependent aldehyde dehydrogenases; NAD-dependent aldehyde dehydrogenase 1641501 ssdh 3251449 ssdh Lactobacillus acidophilus NCFM NAD-dependent aldehyde dehydrogenase YP_194476.1 1640119 D 272621 CDS YP_194477.1 58337892 3251448 complement(1641635..1646614) 1 NC_006814.3 surface protein 1646614 3251448 LBA1633 Lactobacillus acidophilus NCFM surface protein YP_194477.1 1641635 R 272621 CDS YP_194478.1 58337893 3251304 complement(1647109..1652883) 1 NC_006814.3 Rlp; surface protein 1652883 3251304 LBA1634 Lactobacillus acidophilus NCFM surface protein YP_194478.1 1647109 R 272621 CDS YP_194479.1 58337894 3251302 complement(1653262..1654305) 1 NC_006814.3 hypothetical protein 1654305 3251302 LBA1636 Lactobacillus acidophilus NCFM hypothetical protein YP_194479.1 1653262 R 272621 CDS YP_194480.1 58337895 3251303 complement(1654420..1658133) 1 NC_006814.3 membrane protein 1658133 3251303 LBA1637 Lactobacillus acidophilus NCFM membrane protein YP_194480.1 1654420 R 272621 CDS YP_194481.1 58337896 3251451 complement(1658149..1658712) 1 NC_006814.3 COG1309 transcriptional regulator, TetR family; transcriptional regulator 1658712 tetR 3251451 tetR Lactobacillus acidophilus NCFM transcriptional regulator YP_194481.1 1658149 R 272621 CDS YP_194482.1 58337897 3251450 complement(1658853..1659809) 1 NC_006814.3 COG2367 Beta-lactamase class A; beta-lactamase 1659809 3251450 LBA1639 Lactobacillus acidophilus NCFM beta-lactamase YP_194482.1 1658853 R 272621 CDS YP_194483.1 58337898 3251337 complement(1659826..1660785) 1 NC_006814.3 CorA family cationic transporter 1660785 corA 3251337 corA Lactobacillus acidophilus NCFM CorA family cationic transporter YP_194483.1 1659826 R 272621 CDS YP_194484.1 58337899 3251388 complement(1660864..1662165) 1 NC_006814.3 glycerol-3-phosphate ABC transporter 1662165 3251388 LBA1641 Lactobacillus acidophilus NCFM glycerol-3-phosphate ABC transporter YP_194484.1 1660864 R 272621 CDS YP_194485.1 58337900 3251387 complement(1662219..1663514) 1 NC_006814.3 hypothetical protein 1663514 3251387 LBA1642 Lactobacillus acidophilus NCFM hypothetical protein YP_194485.1 1662219 R 272621 CDS YP_194486.1 58337901 3251389 complement(1663498..1664322) 1 NC_006814.3 sugar ABC transporter 1664322 3251389 LBA1643 Lactobacillus acidophilus NCFM sugar ABC transporter YP_194486.1 1663498 R 272621 CDS YP_194487.1 58337902 3251341 complement(1664354..1665193) 1 NC_006814.3 sugar ABC transporter permease 1665193 3251341 LBA1644 Lactobacillus acidophilus NCFM sugar ABC transporter permease YP_194487.1 1664354 R 272621 CDS YP_194488.1 58337903 3251338 complement(1665193..1666278) 1 NC_006814.3 multiple sugar-binding ABC-transporter ATPase 1666278 3251338 LBA1645 Lactobacillus acidophilus NCFM multiple sugar-binding ABC-transporter ATPase YP_194488.1 1665193 R 272621 CDS YP_194489.1 58337904 3251339 complement(1666539..1667966) 1 NC_006814.3 COG4690 Dipeptidase; dipeptidase 1667966 3251339 LBA1646 Lactobacillus acidophilus NCFM dipeptidase YP_194489.1 1666539 R 272621 CDS YP_194490.1 58337905 3251340 complement(1668009..1668866) 1 NC_006814.3 DNA nuclease 1668866 3251340 LBA1647 Lactobacillus acidophilus NCFM DNA nuclease YP_194490.1 1668009 R 272621 CDS YP_194491.1 58337906 3251572 complement(1668876..1669832) 1 NC_006814.3 DNA polymerase III 1669832 3251572 LBA1648 Lactobacillus acidophilus NCFM DNA polymerase III YP_194491.1 1668876 R 272621 CDS YP_194492.1 58337907 3251571 complement(1669840..1670640) 1 NC_006814.3 hypothetical protein 1670640 3251571 LBA1649 Lactobacillus acidophilus NCFM hypothetical protein YP_194492.1 1669840 R 272621 CDS YP_194493.1 58337908 3251570 complement(1670659..1671297) 1 NC_006814.3 COG2323 Predicted membrane protein; hypothetical protein 1671297 3251570 LBA1650 Lactobacillus acidophilus NCFM hypothetical protein YP_194493.1 1670659 R 272621 CDS YP_194494.1 58337909 3251531 complement(1671300..1671749) 1 NC_006814.3 hypothetical protein 1671749 3251531 LBA1651 Lactobacillus acidophilus NCFM hypothetical protein YP_194494.1 1671300 R 272621 CDS YP_194495.1 58337910 3251534 complement(1671822..1675346) 1 NC_006814.3 cell surface protein precursor; mucus binding protein precursor Mub 1675346 3251534 LBA1652 Lactobacillus acidophilus NCFM mucus binding protein precursor Mub YP_194495.1 1671822 R 272621 CDS YP_194496.1 58337911 3251409 complement(1675689..1676426) 1 NC_006814.3 COG3201 Nicotinamide mononucleotide transporter; nicotinamide mononucleotide 1676426 3251409 LBA1653 Lactobacillus acidophilus NCFM nicotinamide mononucleotide YP_194496.1 1675689 R 272621 CDS YP_194497.1 58337912 3251408 1676702..1678759 1 NC_006814.3 surface protein PspC; surface protein 1678759 pspC 3251408 pspC Lactobacillus acidophilus NCFM surface protein YP_194497.1 1676702 D 272621 CDS YP_194498.1 58337913 3251535 1678847..1679137 1 NC_006814.3 RecA protein (Recombinase A); hypothetical protein 1679137 3251535 LBA1655 Lactobacillus acidophilus NCFM hypothetical protein YP_194498.1 1678847 D 272621 CDS YP_194499.1 58337914 3251536 complement(1679199..1679942) 1 NC_006814.3 COG2461 Uncharacterized conserved protein; hypothetical protein 1679942 3251536 LBA1656 Lactobacillus acidophilus NCFM hypothetical protein YP_194499.1 1679199 R 272621 CDS YP_194500.1 58337915 3251411 complement(1680127..1681731) 1 NC_006814.3 ABC transporter 1681731 3251411 LBA1657 Lactobacillus acidophilus NCFM ABC transporter YP_194500.1 1680127 R 272621 CDS YP_194501.1 58337916 3251410 1681849..1682766 1 NC_006814.3 prolinase; prolyl aminopeptidase 1682766 3251410 LBA1658 Lactobacillus acidophilus NCFM prolyl aminopeptidase YP_194501.1 1681849 D 272621 CDS YP_194502.1 58337917 3251249 1682825..1683526 1 NC_006814.3 response regulator 1683526 3251249 LBA1659 Lactobacillus acidophilus NCFM response regulator YP_194502.1 1682825 D 272621 CDS YP_194503.1 58337918 3251584 1683528..1684853 1 NC_006814.3 sensor protein 1684853 3251584 LBA1660 Lactobacillus acidophilus NCFM sensor protein YP_194503.1 1683528 D 272621 CDS YP_194504.1 58337919 3251583 1684971..1685513 1 NC_006814.3 COG3212 Predicted membrane protein; hypothetical protein 1685513 3251583 LBA1661 Lactobacillus acidophilus NCFM hypothetical protein YP_194504.1 1684971 D 272621 CDS YP_194505.1 58337920 3251251 1685532..1686140 1 NC_006814.3 COG3212 Predicted membrane protein; hypothetical protein 1686140 3251251 LBA1662 Lactobacillus acidophilus NCFM hypothetical protein YP_194505.1 1685532 D 272621 CDS YP_194506.1 58337921 3251250 1686227..1686682 1 NC_006814.3 transcriptional regulator 1686682 marR 3251250 marR Lactobacillus acidophilus NCFM transcriptional regulator YP_194506.1 1686227 D 272621 CDS YP_194507.1 58337922 3251422 1686682..1687197 1 NC_006814.3 acetyltransferase 1687197 3251422 LBA1664 Lactobacillus acidophilus NCFM acetyltransferase YP_194507.1 1686682 D 272621 CDS YP_194508.1 58337923 3251421 complement(1687261..1688901) 1 NC_006814.3 OppA; oligopeptide ABC transporter substrate binding protein 1688901 oppA 3251421 oppA Lactobacillus acidophilus NCFM oligopeptide ABC transporter substrate binding protein YP_194508.1 1687261 R 272621 CDS YP_194509.1 58337924 3251420 1689221..1689583 1 NC_006814.3 COG3759 Predicted membrane protein; hypothetical protein 1689583 3251420 LBA1666 Lactobacillus acidophilus NCFM hypothetical protein YP_194509.1 1689221 D 272621 CDS YP_194510.1 58337925 3251397 1689708..1690289 1 NC_006814.3 hypothetical protein 1690289 3251397 LBA1667 Lactobacillus acidophilus NCFM hypothetical protein YP_194510.1 1689708 D 272621 CDS YP_194511.1 58337926 3251395 complement(1690349..1690924) 1 NC_006814.3 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 1690924 3251395 LBA1668 Lactobacillus acidophilus NCFM elongation factor P YP_194511.1 1690349 R 272621 CDS YP_194512.1 58337927 3251423 complement(1691048..1691962) 1 NC_006814.3 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 1691962 coaA 3251423 coaA Lactobacillus acidophilus NCFM pantothenate kinase YP_194512.1 1691048 R 272621 CDS YP_194513.1 58337928 3251396 1692019..1692579 1 NC_006814.3 arylesterase 1692579 3251396 LBA1670 Lactobacillus acidophilus NCFM arylesterase YP_194513.1 1692019 D 272621 CDS YP_194514.1 58337929 3251233 complement(1692576..1693028) 1 NC_006814.3 acetyltransferase 1693028 3251233 LBA1671 Lactobacillus acidophilus NCFM acetyltransferase YP_194514.1 1692576 R 272621 CDS YP_194515.1 58337930 3251232 complement(1693031..1693849) 1 NC_006814.3 amino acid ABC transporter 1693849 3251232 LBA1672 Lactobacillus acidophilus NCFM amino acid ABC transporter YP_194515.1 1693031 R 272621 CDS YP_194516.1 58337931 3251399 complement(1693853..1694473) 1 NC_006814.3 GlnQ; glutamine ABC transporter 1694473 glnQ 3251399 glnQ Lactobacillus acidophilus NCFM glutamine ABC transporter YP_194516.1 1693853 R 272621 CDS YP_194517.1 58337932 3251231 complement(1694487..1695134) 1 NC_006814.3 amino acid ABC transporter permease 1695134 3251231 LBA1674 Lactobacillus acidophilus NCFM amino acid ABC transporter permease YP_194517.1 1694487 R 272621 CDS YP_194518.1 58337933 3251236 complement(1695566..1695772) 1 NC_006814.3 hypothetical protein 1695772 3251236 LBA1675 Lactobacillus acidophilus NCFM hypothetical protein YP_194518.1 1695566 R 272621 CDS YP_194519.1 58337934 3251234 complement(1695808..1697871) 1 NC_006814.3 ATP-dependent helicase 1697871 3251234 LBA1676 Lactobacillus acidophilus NCFM ATP-dependent helicase YP_194519.1 1695808 R 272621 CDS YP_194520.1 58337935 3251235 1698026..1698709 1 NC_006814.3 hypothetical protein 1698709 3251235 LBA1677 Lactobacillus acidophilus NCFM hypothetical protein YP_194520.1 1698026 D 272621 CDS YP_194521.1 58337936 3251245 1698772..1699422 1 NC_006814.3 COG0406 Fructose-2,6-bisphosphatase; phosphoglycerate mutase 1699422 3251245 LBA1678 Lactobacillus acidophilus NCFM phosphoglycerate mutase YP_194521.1 1698772 D 272621 CDS YP_194522.1 58337937 3251244 complement(1699455..1701257) 1 NC_006814.3 ABC transporter permease 1701257 3251244 LBA1679 Lactobacillus acidophilus NCFM ABC transporter permease YP_194522.1 1699455 R 272621 CDS YP_194523.1 58337938 3251243 complement(1701268..1702017) 1 NC_006814.3 ABC transporter ATP-binding protein 1702017 3251243 LBA1680 Lactobacillus acidophilus NCFM ABC transporter ATP-binding protein YP_194523.1 1701268 R 272621 CDS YP_194524.1 58337939 3251242 complement(1702166..1703437) 1 NC_006814.3 hypothetical protein 1703437 3251242 LBA1681 Lactobacillus acidophilus NCFM hypothetical protein YP_194524.1 1702166 R 272621 CDS YP_194525.1 58337940 3251355 1703533..1704219 1 NC_006814.3 similar to ORF1 TT-virus; hypothetical protein 1704219 3251355 LBA1682 Lactobacillus acidophilus NCFM hypothetical protein YP_194525.1 1703533 D 272621 CDS YP_194526.1 58337941 3251351 complement(1704232..1706871) 1 NC_006814.3 Calcium-transporting ATPase; cation-transporting ATPase 1706871 pacL 3251351 pacL Lactobacillus acidophilus NCFM cation-transporting ATPase YP_194526.1 1704232 R 272621 CDS YP_194527.1 58337942 3251576 complement(1707045..1707437) 1 NC_006814.3 COG2893 Phosphotransferase system, mannose-fructose-specific component IIA; PTS system transporter subunit IIA 1707437 3251576 LBA1684 Lactobacillus acidophilus NCFM PTS system transporter subunit IIA YP_194527.1 1707045 R 272621 CDS YP_194528.1 58337943 3251575 complement(1707586..1707885) 1 NC_006814.3 hypothetical protein 1707885 3251575 LBA1685 Lactobacillus acidophilus NCFM hypothetical protein YP_194528.1 1707586 R 272621 CDS YP_194529.1 58337944 3251574 complement(1707963..1708100) 1 NC_006814.3 hypothetical protein 1708100 3251574 LBA1686 Lactobacillus acidophilus NCFM hypothetical protein YP_194529.1 1707963 R 272621 CDS YP_194530.1 58337945 3251354 complement(1708198..1709190) 1 NC_006814.3 l-asparaginase 1709190 ansA 3251354 ansA Lactobacillus acidophilus NCFM l-asparaginase YP_194530.1 1708198 R 272621 CDS YP_194531.1 58337946 3251356 complement(1709200..1709982) 1 NC_006814.3 family; RpiR; similar to hypothetical protein; transcriptional regulator 1709982 rpiR 3251356 rpiR Lactobacillus acidophilus NCFM transcriptional regulator YP_194531.1 1709200 R 272621 CDS YP_194532.1 58337947 3251573 complement(1710079..1711416) 1 NC_006814.3 Maltose-6'-phosphate glucosidase (6-phospho-alpha-D-glucosidase); maltose-6'-phosphate glucosidase 1711416 malH 3251573 malH Lactobacillus acidophilus NCFM maltose-6'-phosphate glucosidase YP_194532.1 1710079 R 272621 CDS YP_194533.1 58337948 3251578 1712129..1712971 1 NC_006814.3 surface exclusion protein; hypothetical protein 1712971 3251578 LBA1690 Lactobacillus acidophilus NCFM hypothetical protein YP_194533.1 1712129 D 272621 CDS YP_194534.1 58337949 3251577 1713450..1713950 1 NC_006814.3 transcriptional regulator 1713950 3251577 LBA1691 Lactobacillus acidophilus NCFM transcriptional regulator YP_194534.1 1713450 D 272621 CDS YP_194535.1 58337950 3251367 complement(1713978..1714541) 1 NC_006814.3 GNAT family; acetyltransferase 1714541 3251367 LBA1692 Lactobacillus acidophilus NCFM acetyltransferase YP_194535.1 1713978 R 272621 CDS YP_194536.1 58337951 3251366 complement(1714691..1714810) 1 NC_006814.3 hypothetical protein 1714810 3251366 LBA1693 Lactobacillus acidophilus NCFM hypothetical protein YP_194536.1 1714691 R 272621 CDS YP_194537.1 58337952 3251369 complement(1715173..1715301) 1 NC_006814.3 hypothetical protein 1715301 3251369 LBA1694 Lactobacillus acidophilus NCFM hypothetical protein YP_194537.1 1715173 R 272621 CDS YP_194538.1 58337953 3251368 1715785..1717383 1 NC_006814.3 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 1717383 3251368 LBA1695 Lactobacillus acidophilus NCFM aspartate aminotransferase YP_194538.1 1715785 D 272621 CDS YP_194539.1 58337954 3251434 1717399..1719057 1 NC_006814.3 aspartate alanine antiporter 1719057 3251434 LBA1696 Lactobacillus acidophilus NCFM aspartate alanine antiporter YP_194539.1 1717399 D 272621 CDS YP_194540.1 58337955 3251433 complement(1719195..1720205) 1 NC_006814.3 hypothetical protein 1720205 3251433 LBA1697 Lactobacillus acidophilus NCFM hypothetical protein YP_194540.1 1719195 R 272621 CDS YP_194541.1 58337956 3251436 complement(1720218..1721282) 1 NC_006814.3 protein; prophage related protein 1721282 3251436 LBA1698 Lactobacillus acidophilus NCFM prophage related protein YP_194541.1 1720218 R 272621 CDS YP_194542.1 58337957 3251435 complement(1721383..1722144) 1 NC_006814.3 COG0708 Exonuclease III; exodeoxyribonuclease 1722144 exoA 3251435 exoA Lactobacillus acidophilus NCFM exodeoxyribonuclease YP_194542.1 1721383 R 272621 CDS YP_194543.1 58337958 3251529 complement(1722309..1723388) 1 NC_006814.3 AraC; transcriptional regulator -type 1723388 3251529 LBA1700 Lactobacillus acidophilus NCFM transcriptional regulator -type YP_194543.1 1722309 R 272621 CDS YP_194544.1 58337959 3251527 complement(1723898..1724914) 1 NC_006814.3 transcriptional regulator, AraC family; melibiose operon regulatory protein 1724914 3251527 LBA1701 Lactobacillus acidophilus NCFM melibiose operon regulatory protein YP_194544.1 1723898 R 272621 CDS YP_194545.1 58337960 3251525 complement(1726886..1727740) 1 NC_006814.3 family; RpiR; transcriptional regulator 1727740 rpiR 3251525 rpiR Lactobacillus acidophilus NCFM transcriptional regulator YP_194545.1 1726886 R 272621 CDS YP_194546.1 58337961 3251526 complement(1727750..1728811) 1 NC_006814.3 hypothetical protein 1728811 3251526 LBA1703 Lactobacillus acidophilus NCFM hypothetical protein YP_194546.1 1727750 R 272621 CDS YP_194547.1 58337962 3251528 complement(1728870..1729766) 1 NC_006814.3 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid 6-phosphate etherase 1729766 murQ 3251528 murQ Lactobacillus acidophilus NCFM N-acetylmuramic acid 6-phosphate etherase YP_194547.1 1728870 R 272621 CDS YP_194548.1 58337963 3251530 complement(1729778..1731769) 1 NC_006814.3 sucrose PTS, EIIBC; PTS system transporter subunit IIBC 1731769 3251530 LBA1705 Lactobacillus acidophilus NCFM PTS system transporter subunit IIBC YP_194548.1 1729778 R 272621 CDS YP_194549.1 58337964 3251293 complement(1732095..1733576) 1 NC_006814.3 COG2723 Beta-glucosidase-6-phospho-beta-glucosidase -beta-galactosidase; 6-phospho-beta-glucosidase 1733576 3251293 LBA1706 Lactobacillus acidophilus NCFM 6-phospho-beta-glucosidase YP_194549.1 1732095 R 272621 CDS YP_194550.1 58337965 3251295 complement(1733589..1735466) 1 NC_006814.3 beta-glucoside permease 1735466 3251295 LBA1707 Lactobacillus acidophilus NCFM beta-glucoside permease YP_194550.1 1733589 R 272621 CDS YP_194551.1 58337966 3251294 complement(1735463..1736317) 1 NC_006814.3 COG3711 transcriptional antiterminator; transcriptional antiterminator 1736317 licT 3251294 licT Lactobacillus acidophilus NCFM transcriptional antiterminator YP_194551.1 1735463 R 272621 CDS YP_194552.1 58337967 3251297 complement(1736469..1740095) 1 NC_006814.3 mucus binding protein precursor Mub 1740095 3251297 LBA1709 Lactobacillus acidophilus NCFM mucus binding protein precursor Mub YP_194552.1 1736469 R 272621 CDS YP_194553.1 58337968 3251299 complement(1740378..1743935) 1 NC_006814.3 pullulanase; thermostable pullulanase 1743935 amyX 3251299 amyX Lactobacillus acidophilus NCFM thermostable pullulanase YP_194553.1 1740378 R 272621 CDS YP_194554.1 58337969 3251554 complement(1744176..1744685) 1 NC_006814.3 sulfotransferase; hypothetical protein 1744685 3251554 LBA1711 Lactobacillus acidophilus NCFM hypothetical protein YP_194554.1 1744176 R 272621 CDS YP_194555.1 58337970 3251555 complement(1744723..1745667) 1 NC_006814.3 pneumococcal surface protein A; hypothetical protein 1745667 3251555 LBA1712 Lactobacillus acidophilus NCFM hypothetical protein YP_194555.1 1744723 R 272621 CDS YP_194556.1 58337971 3251557 complement(1745938..1747656) 1 NC_006814.3 hypothetical protein 1747656 3251557 LBA1713 Lactobacillus acidophilus NCFM hypothetical protein YP_194556.1 1745938 R 272621 CDS YP_194557.1 58337972 3251558 complement(1747869..1748459) 1 NC_006814.3 hypothetical protein 1748459 3251558 LBA1714 Lactobacillus acidophilus NCFM hypothetical protein YP_194557.1 1747869 R 272621 CDS YP_194558.1 58337973 3251559 complement(1748452..1748634) 1 NC_006814.3 hypothetical protein 1748634 3251559 LBA1715 Lactobacillus acidophilus NCFM hypothetical protein YP_194558.1 1748452 R 272621 CDS YP_194559.1 58337974 3251325 complement(1750130..1751326) 1 NC_006814.3 GLP_178_26121_9007; hypothetical protein 1751326 3251325 LBA1716 Lactobacillus acidophilus NCFM hypothetical protein YP_194559.1 1750130 R 272621 CDS YP_194560.1 58337975 3251326 complement(1752104..1753225) 1 NC_006814.3 mutant sensor protein 1753225 agrC 3251326 agrC Lactobacillus acidophilus NCFM mutant sensor protein YP_194560.1 1752104 R 272621 CDS YP_194561.1 58337976 3251320 complement(1753493..1754275) 1 NC_006814.3 hypothetical protein 1754275 3251320 LBA1718 Lactobacillus acidophilus NCFM hypothetical protein YP_194561.1 1753493 R 272621 CDS YP_194562.1 58337977 3251328 complement(1754392..1755276) 1 NC_006814.3 COG1210 UDP-glucose pyrophosphorylase; UTP-glucose-1-phosphate uridylyltransferase 1755276 3251328 LBA1719 Lactobacillus acidophilus NCFM UTP-glucose-1-phosphate uridylyltransferase YP_194562.1 1754392 R 272621 CDS YP_194563.1 58337978 3251323 1755431..1756573 1 NC_006814.3 COG0381 UDP-N-acetylglucosamine 2-epimerase; UDP-N-acetyl glucosamine-2-epimerase 1756573 3251323 LBA1720 Lactobacillus acidophilus NCFM UDP-N-acetyl glucosamine-2-epimerase YP_194563.1 1755431 D 272621 CDS YP_194564.1 58337979 3251322 complement(1756648..1757007) 1 NC_006814.3 potential frameshift to 1722; transposase 1757007 3251322 LBA1721 Lactobacillus acidophilus NCFM transposase YP_194564.1 1756648 R 272621 CDS YP_194565.1 58337980 3251324 complement(1756970..1757710) 1 NC_006814.3 potential frameshift to 1721; transposase 1757710 3251324 LBA1722 Lactobacillus acidophilus NCFM transposase YP_194565.1 1756970 R 272621 CDS YP_194566.1 58337981 3251360 1757980..1759206 1 NC_006814.3 transposase 1759206 3251360 LBA1723 Lactobacillus acidophilus NCFM transposase YP_194566.1 1757980 D 272621 CDS YP_194567.1 58337982 3251361 complement(1759462..1760895) 1 NC_006814.3 oligosaccharide repeat-containing polymerase 1760895 epsI 3251361 epsI Lactobacillus acidophilus NCFM oligosaccharide repeat-containing polymerase YP_194567.1 1759462 R 272621 CDS YP_194568.1 58337983 3251363 complement(1760901..1761413) 1 NC_006814.3 COG0562 UDP-galactopyranose mutase; UDP-galactopyranose mutase 1761413 epsJ 3251363 epsJ Lactobacillus acidophilus NCFM UDP-galactopyranose mutase YP_194568.1 1760901 R 272621 CDS YP_194569.1 58337984 3251258 complement(1761612..1762013) 1 NC_006814.3 potential frameshift to 1725; UDP-galactopyranose mutase; udpgalactopyranose mutase 1762013 3251258 LBA1726 Lactobacillus acidophilus NCFM udpgalactopyranose mutase YP_194569.1 1761612 R 272621 CDS YP_194570.1 58337985 3251259 complement(1762010..1763305) 1 NC_006814.3 polysaccharide polymerase 1763305 3251259 LBA1727 Lactobacillus acidophilus NCFM polysaccharide polymerase YP_194570.1 1762010 R 272621 CDS YP_194571.1 58337986 3251262 complement(1763330..1764370) 1 NC_006814.3 glycosyl transferase family protein 1764370 3251262 LBA1728 Lactobacillus acidophilus NCFM glycosyl transferase family protein YP_194571.1 1763330 R 272621 CDS YP_194572.1 58337987 3251264 complement(1764367..1765023) 1 NC_006814.3 hypothetical protein 1765023 3251264 LBA1729 Lactobacillus acidophilus NCFM hypothetical protein YP_194572.1 1764367 R 272621 CDS YP_194573.1 58337988 3251265 complement(1764992..1765513) 1 NC_006814.3 COG0058 Glucan phosphorylase; hypothetical protein 1765513 3251265 LBA1730 Lactobacillus acidophilus NCFM hypothetical protein YP_194573.1 1764992 R 272621 CDS YP_194574.1 58337989 3251274 complement(1765526..1766407) 1 NC_006814.3 COG1216 Predicted glycosyltransferases; glycosyltransferase 1766407 3251274 LBA1731 Lactobacillus acidophilus NCFM glycosyltransferase YP_194574.1 1765526 R 272621 CDS YP_194575.1 58337990 3251273 complement(1766424..1767197) 1 NC_006814.3 glycosyltransferase; galactosyl transferase 1767197 epsF 3251273 epsF Lactobacillus acidophilus NCFM galactosyl transferase YP_194575.1 1766424 R 272621 CDS YP_194576.1 58337991 3251275 complement(1767206..1767859) 1 NC_006814.3 EpsE; phospho-glucosyltransferase 1767859 epsE 3251275 epsE Lactobacillus acidophilus NCFM phospho-glucosyltransferase YP_194576.1 1767206 R 272621 CDS YP_194577.1 58337992 3251277 complement(1767949..1768719) 1 NC_006814.3 EpsD; exopolysaccharide biosynthesis protein 1768719 epsD 3251277 epsD Lactobacillus acidophilus NCFM exopolysaccharide biosynthesis protein YP_194577.1 1767949 R 272621 CDS YP_194578.1 58337993 3251279 complement(1768722..1769504) 1 NC_006814.3 EpsC; exopolysaccharide biosynthesis protein 1769504 epsC 3251279 epsC Lactobacillus acidophilus NCFM exopolysaccharide biosynthesis protein YP_194578.1 1768722 R 272621 CDS YP_194579.1 58337994 3251442 complement(1769520..1770395) 1 NC_006814.3 EpsB; exopolysaccharide biosynthesis protein 1770395 epsB 3251442 epsB Lactobacillus acidophilus NCFM exopolysaccharide biosynthesis protein YP_194579.1 1769520 R 272621 CDS YP_194580.1 58337995 3251440 complement(1770417..1771472) 1 NC_006814.3 EpsA; exopolysaccharide biosynthesis protein 1771472 epsA 3251440 epsA Lactobacillus acidophilus NCFM exopolysaccharide biosynthesis protein YP_194580.1 1770417 R 272621 CDS YP_194581.1 58337996 3251443 1771638..1772903 1 NC_006814.3 HflX; COG2262 GTPases; GTP-binding protein 1772903 hflX 3251443 hflX Lactobacillus acidophilus NCFM GTP-binding protein YP_194581.1 1771638 D 272621 CDS YP_194582.1 58337997 3251445 1772919..1773929 1 NC_006814.3 hypothetical protein 1773929 3251445 LBA1739 Lactobacillus acidophilus NCFM hypothetical protein YP_194582.1 1772919 D 272621 CDS YP_194583.1 58337998 3251561 complement(1774540..1778670) 1 NC_006814.3 hypothetical protein 1778670 3251561 LBA1740 Lactobacillus acidophilus NCFM hypothetical protein YP_194583.1 1774540 R 272621 CDS YP_194584.1 58337999 3251565 complement(1778856..1779755) 1 NC_006814.3 cell wall-associated hydrolase 1779755 3251565 LBA1741 Lactobacillus acidophilus NCFM cell wall-associated hydrolase YP_194584.1 1778856 R 272621 CDS YP_194585.1 58338000 3251563 complement(1779910..1780698) 1 NC_006814.3 COG3942 Surface antigen; cell wall-associated hydrolase 1780698 3251563 LBA1743 Lactobacillus acidophilus NCFM cell wall-associated hydrolase YP_194585.1 1779910 R 272621 CDS YP_194586.1 58338001 3251567 complement(1780996..1781550) 1 NC_006814.3 COG3942 Surface antigen; glycosidase 1781550 3251567 LBA1744 Lactobacillus acidophilus NCFM glycosidase YP_194586.1 1780996 R 272621 CDS YP_194587.1 58338002 3251585 complement(1781744..1782193) 1 NC_006814.3 COG0194 Guanylate kinase; guanylate kinase 1782193 3251585 LBA1745 Lactobacillus acidophilus NCFM guanylate kinase YP_194587.1 1781744 R 272621 CDS YP_194588.1 58338003 3251587 1782390..1782689 1 NC_006814.3 hypothetical protein 1782689 3251587 LBA1746 Lactobacillus acidophilus NCFM hypothetical protein YP_194588.1 1782390 D 272621 CDS YP_194589.1 58338004 3251590 1782779..1784290 1 NC_006814.3 hypothetical protein 1784290 3251590 LBA1747 Lactobacillus acidophilus NCFM hypothetical protein YP_194589.1 1782779 D 272621 CDS YP_194590.1 58338005 3251593 complement(1784323..1784943) 1 NC_006814.3 hypothetical protein 1784943 3251593 LBA1748 Lactobacillus acidophilus NCFM hypothetical protein YP_194590.1 1784323 R 272621 CDS YP_194591.1 58338006 3251592 1785067..1785513 1 NC_006814.3 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 1785513 nrdI 3251592 nrdI Lactobacillus acidophilus NCFM ribonucleotide reductase stimulatory protein YP_194591.1 1785067 D 272621 CDS YP_194592.1 58338007 3251594 1785516..1786451 1 NC_006814.3 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 1786451 nrdF 3251594 nrdF Lactobacillus acidophilus NCFM ribonucleotide-diphosphate reductase subunit beta YP_194592.1 1785516 D 272621 CDS YP_194593.1 58338008 3251597 complement(1786486..1787019) 1 NC_006814.3 hypothetical protein 1787019 3251597 LBA1751 Lactobacillus acidophilus NCFM hypothetical protein YP_194593.1 1786486 R 272621 CDS YP_194594.1 58338009 3251598 1787128..1787850 1 NC_006814.3 hypothetical protein 1787850 3251598 LBA1752 Lactobacillus acidophilus NCFM hypothetical protein YP_194594.1 1787128 D 272621 CDS YP_194595.1 58338010 3251601 complement(1787856..1788173) 1 NC_006814.3 hypothetical protein 1788173 3251601 LBA1753 Lactobacillus acidophilus NCFM hypothetical protein YP_194595.1 1787856 R 272621 CDS YP_194596.1 58338011 3251602 complement(1788170..1788466) 1 NC_006814.3 hypothetical protein 1788466 3251602 LBA1754 Lactobacillus acidophilus NCFM hypothetical protein YP_194596.1 1788170 R 272621 CDS YP_194597.1 58338012 3251607 complement(1788447..1788677) 1 NC_006814.3 ABC transporter ATP-binding protein 1788677 3251607 LBA1755 Lactobacillus acidophilus NCFM ABC transporter ATP-binding protein YP_194597.1 1788447 R 272621 CDS YP_194598.1 58338013 3251604 complement(1788750..1788908) 1 NC_006814.3 hypothetical protein 1788908 3251604 LBA1756 Lactobacillus acidophilus NCFM hypothetical protein YP_194598.1 1788750 R 272621 CDS YP_194599.1 58338014 3251605 complement(1788984..1789469) 1 NC_006814.3 COG3610 Uncharacterized conserved protein; hypothetical protein 1789469 3251605 LBA1757 Lactobacillus acidophilus NCFM hypothetical protein YP_194599.1 1788984 R 272621 CDS YP_194600.1 58338015 3251606 complement(1789472..1790242) 1 NC_006814.3 COG2966 Uncharacterized conserved protein; hypothetical protein 1790242 3251606 LBA1758 Lactobacillus acidophilus NCFM hypothetical protein YP_194600.1 1789472 R 272621 CDS YP_194601.1 58338016 3251608 complement(1790253..1791794) 1 NC_006814.3 ABC transporter ATPase 1791794 3251608 LBA1759 Lactobacillus acidophilus NCFM ABC transporter ATPase YP_194601.1 1790253 R 272621 CDS YP_194602.1 58338017 3251610 complement(1791803..1792177) 1 NC_006814.3 hypothetical protein 1792177 3251610 LBA1760 Lactobacillus acidophilus NCFM hypothetical protein YP_194602.1 1791803 R 272621 CDS YP_194604.1 58338019 3251615 complement(1792877..1794151) 1 NC_006814.3 LytR; COG1316 transcriptional regulator; transcriptional regulator 1794151 lytR 3251615 lytR Lactobacillus acidophilus NCFM transcriptional regulator YP_194604.1 1792877 R 272621 CDS YP_194605.1 58338020 3251617 1794320..1796116 1 NC_006814.3 endopeptidase F; oligopeptidase 1796116 pepF 3251617 pepF Lactobacillus acidophilus NCFM oligopeptidase YP_194605.1 1794320 D 272621 CDS YP_194606.1 58338021 3251618 1796193..1796474 1 NC_006814.3 hypothetical protein 1796474 3251618 LBA1765 Lactobacillus acidophilus NCFM hypothetical protein YP_194606.1 1796193 D 272621 CDS YP_194607.1 58338022 3251620 complement(1796807..1798321) 1 NC_006814.3 LctP; COG1620 L-lactate permease; lactate premease 1798321 lctP 3251620 lctP Lactobacillus acidophilus NCFM lactate premease YP_194607.1 1796807 R 272621 CDS YP_194608.1 58338023 3251623 1798726..1799091 1 NC_006814.3 COG3576 Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase; hypothetical protein 1799091 3251623 LBA1769 Lactobacillus acidophilus NCFM hypothetical protein YP_194608.1 1798726 D 272621 CDS YP_194609.1 58338024 3251624 complement(1799140..1799937) 1 NC_006814.3 ABC transporter permease 1799937 3251624 LBA1771 Lactobacillus acidophilus NCFM ABC transporter permease YP_194609.1 1799140 R 272621 CDS YP_194610.1 58338025 3251628 complement(1799934..1800581) 1 NC_006814.3 zinc ABC transporter ATPase 1800581 3251628 LBA1772 Lactobacillus acidophilus NCFM zinc ABC transporter ATPase YP_194610.1 1799934 R 272621 CDS YP_194611.1 58338026 3251629 complement(1800619..1801515) 1 NC_006814.3 PsaA; ABC transporter periplasmatic component 1801515 psaA 3251629 psaA Lactobacillus acidophilus NCFM ABC transporter periplasmatic component YP_194611.1 1800619 R 272621 CDS YP_194612.1 58338027 3251631 complement(1801745..1802023) 1 NC_006814.3 COG0640 Predicted transcriptional regulators; transcriptional regulator 1802023 3251631 LBA1774 Lactobacillus acidophilus NCFM transcriptional regulator YP_194612.1 1801745 R 272621 CDS YP_194613.1 58338028 3251632 1802166..1802603 1 NC_006814.3 hypothetical protein 1802603 3251632 LBA1775 Lactobacillus acidophilus NCFM hypothetical protein YP_194613.1 1802166 D 272621 CDS YP_194614.1 58338029 3251635 1802605..1803018 1 NC_006814.3 hypothetical protein 1803018 3251635 LBA1776 Lactobacillus acidophilus NCFM hypothetical protein YP_194614.1 1802605 D 272621 CDS YP_194615.1 58338030 3251634 complement(1803211..1805208) 1 NC_006814.3 PTS system fructose-specific transporter subunit II 1805208 fruA 3251634 fruA Lactobacillus acidophilus NCFM PTS system fructose-specific transporter subunit II YP_194615.1 1803211 R 272621 CDS YP_194616.1 58338031 3251636 complement(1805232..1806146) 1 NC_006814.3 FruK; fructose-1-phosphate kinase 1806146 fruK 3251636 fruK Lactobacillus acidophilus NCFM fructose-1-phosphate kinase YP_194616.1 1805232 R 272621 CDS YP_194617.1 58338032 3251639 complement(1806148..1806903) 1 NC_006814.3 FruR; repressor of fructose operon 1806903 fruR 3251639 fruR Lactobacillus acidophilus NCFM repressor of fructose operon YP_194617.1 1806148 R 272621 CDS YP_194618.1 58338033 3251640 complement(1807106..1808161) 1 NC_006814.3 hypothetical protein 1808161 3251640 LBA1780 Lactobacillus acidophilus NCFM hypothetical protein YP_194618.1 1807106 R 272621 CDS YP_194619.1 58338034 3251641 complement(1808316..1809536) 1 NC_006814.3 ABC transporter permease 1809536 3251641 LBA1782 Lactobacillus acidophilus NCFM ABC transporter permease YP_194619.1 1808316 R 272621 CDS YP_194620.1 58338035 3251644 complement(1809520..1810416) 1 NC_006814.3 ABC transporter ATP-binding protein 1810416 3251644 LBA1783 Lactobacillus acidophilus NCFM ABC transporter ATP-binding protein YP_194620.1 1809520 R 272621 CDS YP_194621.1 58338036 3251645 complement(1810842..1810943) 1 NC_006814.3 hypothetical protein 1810943 3251645 LBA1784 Lactobacillus acidophilus NCFM hypothetical protein YP_194621.1 1810842 R 272621 CDS YP_194622.1 58338037 3251647 complement(1810962..1811384) 1 NC_006814.3 chloride channel protein; hypothetical protein 1811384 3251647 LBA1786 Lactobacillus acidophilus NCFM hypothetical protein YP_194622.1 1810962 R 272621 CDS YP_194623.1 58338038 3251649 complement(1811418..1811612) 1 NC_006814.3 hypothetical protein 1811612 3251649 LBA1787 Lactobacillus acidophilus NCFM hypothetical protein YP_194623.1 1811418 R 272621 CDS YP_194624.1 58338039 3251651 complement(1811745..1811954) 1 NC_006814.3 transcriptional regulator 1811954 3251651 LBA1788 Lactobacillus acidophilus NCFM transcriptional regulator YP_194624.1 1811745 R 272621 CDS YP_194625.1 58338040 3251653 complement(1811969..1812508) 1 NC_006814.3 vasotocin VT1 receptor; hypothetical protein 1812508 3251653 LBA1789 Lactobacillus acidophilus NCFM hypothetical protein YP_194625.1 1811969 R 272621 CDS YP_194626.1 58338041 3251656 complement(1812513..1812695) 1 NC_006814.3 vacuolar sorting receptor protein homolog PV72 -cucur bit; hypothetical protein 1812695 3251656 LBA1790 Lactobacillus acidophilus NCFM hypothetical protein YP_194626.1 1812513 R 272621 CDS YP_194627.1 58338042 3251657 complement(1813284..1813478) 1 NC_006814.3 hypothetical protein 1813478 3251657 LBA1791 Lactobacillus acidophilus NCFM hypothetical protein YP_194627.1 1813284 R 272621 CDS YP_194628.1 58338043 3251659 complement(1813644..1813835) 1 NC_006814.3 assimilatory nitrate reductase (electron transfer subunit); hypothetical protein 1813835 3251659 LBA1792 Lactobacillus acidophilus NCFM hypothetical protein YP_194628.1 1813644 R 272621 CDS YP_194629.1 58338044 3251661 complement(1813836..1815152) 1 NC_006814.3 hypothetical protein 1815152 3251661 LBA1793 Lactobacillus acidophilus NCFM hypothetical protein YP_194629.1 1813836 R 272621 CDS YP_194630.1 58338045 3251662 complement(1815318..1815908) 1 NC_006814.3 gassericin K7 B accessory protein 1815908 3251662 LBA1794 Lactobacillus acidophilus NCFM gassericin K7 B accessory protein YP_194630.1 1815318 R 272621 CDS YP_194631.1 58338046 3251664 complement(1815919..1818081) 1 NC_006814.3 PlnG; ABC transporter 1818081 plnG 3251664 plnG Lactobacillus acidophilus NCFM ABC transporter YP_194631.1 1815919 R 272621 CDS YP_194632.1 58338047 3251668 complement(1818712..1818963) 1 NC_006814.3 hypothetical protein 1818963 3251668 LBA1797 Lactobacillus acidophilus NCFM hypothetical protein YP_194632.1 1818712 R 272621 CDS YP_194633.1 58338048 3251667 complement(1819156..1819980) 1 NC_006814.3 AbpR; response regulator 1819980 3251667 LBA1798 Lactobacillus acidophilus NCFM response regulator YP_194633.1 1819156 R 272621 CDS YP_194634.1 58338049 3251669 complement(1819949..1821271) 1 NC_006814.3 AbpK; histidine kinase 1821271 3251669 LBA1799 Lactobacillus acidophilus NCFM histidine kinase YP_194634.1 1819949 R 272621 CDS YP_194635.1 58338050 3251672 complement(1821278..1821421) 1 NC_006814.3 hypothetical protein 1821421 3251672 LBA1800 Lactobacillus acidophilus NCFM hypothetical protein YP_194635.1 1821278 R 272621 CDS YP_194636.1 58338051 3251674 complement(1821476..1821592) 1 NC_006814.3 hypothetical protein 1821592 3251674 LBA1801 Lactobacillus acidophilus NCFM hypothetical protein YP_194636.1 1821476 R 272621 CDS YP_194637.1 58338052 3251673 complement(1821552..1821743) 1 NC_006814.3 hypothetical protein 1821743 3251673 LBA1802 Lactobacillus acidophilus NCFM hypothetical protein YP_194637.1 1821552 R 272621 CDS YP_194638.1 58338053 3251676 complement(1821856..1822017) 1 NC_006814.3 hypothetical protein 1822017 3251676 LBA1803 Lactobacillus acidophilus NCFM hypothetical protein YP_194638.1 1821856 R 272621 CDS YP_194639.1 58338054 3251678 complement(1822189..1822815) 1 NC_006814.3 hypothetical protein 1822815 3251678 LBA1804 Lactobacillus acidophilus NCFM hypothetical protein YP_194639.1 1822189 R 272621 CDS YP_194640.1 58338055 3251682 complement(1822871..1823047) 1 NC_006814.3 bHLH transcriptional factor; hypothetical protein 1823047 3251682 LBA1805 Lactobacillus acidophilus NCFM hypothetical protein YP_194640.1 1822871 R 272621 CDS YP_194643.1 58338058 3251686 complement(1824505..1825701) 1 NC_006814.3 hypothetical protein 1825701 3251686 LBA1810 Lactobacillus acidophilus NCFM hypothetical protein YP_194643.1 1824505 R 272621 CDS YP_194644.1 58338059 3251687 complement(1826360..1826671) 1 NC_006814.3 hypothetical protein 1826671 3251687 LBA1811 Lactobacillus acidophilus NCFM hypothetical protein YP_194644.1 1826360 R 272621 CDS YP_194645.1 58338060 3251688 complement(1827103..1829406) 1 NC_006814.3 alpha-glucosidase 1829406 3251688 LBA1812 Lactobacillus acidophilus NCFM alpha-glucosidase YP_194645.1 1827103 R 272621 CDS YP_194646.1 58338061 3251689 complement(1829512..1829703) 1 NC_006814.3 hypothetical protein 1829703 3251689 LBA1813 Lactobacillus acidophilus NCFM hypothetical protein YP_194646.1 1829512 R 272621 CDS YP_194647.1 58338062 3251692 complement(1829782..1830009) 1 NC_006814.3 hypothetical protein 1830009 3251692 LBA1814 Lactobacillus acidophilus NCFM hypothetical protein YP_194647.1 1829782 R 272621 CDS YP_194648.1 58338063 3251693 complement(1830083..1830406) 1 NC_006814.3 hypothetical protein 1830406 3251693 LBA1815 Lactobacillus acidophilus NCFM hypothetical protein YP_194648.1 1830083 R 272621 CDS YP_194649.1 58338064 3251695 complement(1830489..1830842) 1 NC_006814.3 hypothetical protein 1830842 3251695 LBA1816 Lactobacillus acidophilus NCFM hypothetical protein YP_194649.1 1830489 R 272621 CDS YP_194650.1 58338065 3251694 complement(1830853..1831602) 1 NC_006814.3 COG1794 Aspartate racemase; aspartate racemase 1831602 3251694 LBA1817 Lactobacillus acidophilus NCFM aspartate racemase YP_194650.1 1830853 R 272621 CDS YP_194651.1 58338066 3251696 complement(1831613..1833184) 1 NC_006814.3 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 1833184 murE 3251696 murE Lactobacillus acidophilus NCFM UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_194651.1 1831613 R 272621 CDS YP_194652.1 58338067 3251700 complement(1833240..1834385) 1 NC_006814.3 VanS; two-component sensor histidine kinase-like protein 1834385 3251700 LBA1819 Lactobacillus acidophilus NCFM two-component sensor histidine kinase-like protein YP_194652.1 1833240 R 272621 CDS YP_194653.1 58338068 3251702 complement(1834387..1835073) 1 NC_006814.3 COG0745 Response regulators conserved isting of a CheY-like receiver domain and a winged-helix DNA-binding domain; two-component response regulator 1835073 3251702 LBA1820 Lactobacillus acidophilus NCFM two-component response regulator YP_194653.1 1834387 R 272621 CDS YP_194654.1 58338069 3251701 complement(1835222..1837087) 1 NC_006814.3 ABC transporter ATPase 1837087 3251701 LBA1821 Lactobacillus acidophilus NCFM ABC transporter ATPase YP_194654.1 1835222 R 272621 CDS YP_194655.1 58338070 3251704 complement(1837089..1838819) 1 NC_006814.3 ABC transporter ATPase 1838819 3251704 LBA1822 Lactobacillus acidophilus NCFM ABC transporter ATPase YP_194655.1 1837089 R 272621 CDS YP_194656.1 58338071 3251703 complement(1838935..1839717) 1 NC_006814.3 hypothetical protein 1839717 3251703 LBA1823 Lactobacillus acidophilus NCFM hypothetical protein YP_194656.1 1838935 R 272621 CDS YP_194657.1 58338072 3251707 complement(1839727..1840827) 1 NC_006814.3 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 1840827 ychF 3251707 ychF Lactobacillus acidophilus NCFM GTP-dependent nucleic acid-binding protein EngD YP_194657.1 1839727 R 272621 CDS YP_194658.1 58338073 3251705 complement(1840884..1841147) 1 NC_006814.3 hypothetical protein 1841147 3251705 LBA1825 Lactobacillus acidophilus NCFM hypothetical protein YP_194658.1 1840884 R 272621 CDS YP_194659.1 58338074 3251706 complement(1841140..1842024) 1 NC_006814.3 COG1475 Predicted transcriptional regulators; chromosome partitioning protein 1842024 parB 3251706 parB Lactobacillus acidophilus NCFM chromosome partitioning protein YP_194659.1 1841140 R 272621 CDS YP_194660.1 58338075 3251708 complement(1842002..1842781) 1 NC_006814.3 chromosome partitioning protein 1842781 parA 3251708 parA Lactobacillus acidophilus NCFM chromosome partitioning protein YP_194660.1 1842002 R 272621 CDS YP_194661.1 58338076 3251709 complement(1842797..1843627) 1 NC_006814.3 COG1475 Predicted transcriptional regulators; chromosome partitioning protein 1843627 parB 3251709 parB Lactobacillus acidophilus NCFM chromosome partitioning protein YP_194661.1 1842797 R 272621 CDS YP_194662.1 58338077 3251711 complement(1843645..1844367) 1 NC_006814.3 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 1844367 gidB 3251711 gidB Lactobacillus acidophilus NCFM 16S rRNA methyltransferase GidB YP_194662.1 1843645 R 272621 CDS YP_194663.1 58338078 3251714 1844552..1845088 1 NC_006814.3 hypothetical protein 1845088 3251714 LBA1830 Lactobacillus acidophilus NCFM hypothetical protein YP_194663.1 1844552 D 272621 CDS YP_194664.1 58338079 3251715 complement(1845121..1846050) 1 NC_006814.3 ApbE; thiamine biosynthesis lipoprotein 1846050 apbE 3251715 apbE Lactobacillus acidophilus NCFM thiamine biosynthesis lipoprotein YP_194664.1 1845121 R 272621 CDS YP_194665.1 58338080 3251718 complement(1846054..1846845) 1 NC_006814.3 COG2365 protein tyrosine-serine phosphatase; protein-tyrosine-phosphatase 1846845 3251718 LBA1832 Lactobacillus acidophilus NCFM protein-tyrosine-phosphatase YP_194665.1 1846054 R 272621 CDS YP_194666.1 58338081 3251717 complement(1846932..1847480) 1 NC_006814.3 COG0431 Predicted protein; oxidoreductase 1847480 3251717 LBA1833 Lactobacillus acidophilus NCFM oxidoreductase YP_194666.1 1846932 R 272621 CDS YP_194667.1 58338082 3251724 complement(1847492..1848031) 1 NC_006814.3 COG0431 Predicted protein; oxidoreductase 1848031 3251724 LBA1834 Lactobacillus acidophilus NCFM oxidoreductase YP_194667.1 1847492 R 272621 CDS YP_194668.1 58338083 3251720 complement(1848184..1848807) 1 NC_006814.3 transcriptional regulator 1848807 3251720 LBA1835 Lactobacillus acidophilus NCFM transcriptional regulator YP_194668.1 1848184 R 272621 CDS YP_194669.1 58338084 3251721 complement(1849012..1849164) 1 NC_006814.3 hypothetical protein 1849164 3251721 LBA1836 Lactobacillus acidophilus NCFM hypothetical protein YP_194669.1 1849012 R 272621 CDS YP_194670.1 58338085 3251722 1849260..1850672 1 NC_006814.3 COG4690 Dipeptidase; cytosol non-specific dipeptidase 1850672 3251722 LBA1837 Lactobacillus acidophilus NCFM cytosol non-specific dipeptidase YP_194670.1 1849260 D 272621 CDS YP_194671.1 58338086 3251723 complement(1850711..1851385) 1 NC_006814.3 ABC transporter ATP-binding protein 1851385 3251723 LBA1838 Lactobacillus acidophilus NCFM ABC transporter ATP-binding protein YP_194671.1 1850711 R 272621 CDS YP_194672.1 58338087 3251725 complement(1851387..1852448) 1 NC_006814.3 ABC transporter permease 1852448 3251725 LBA1839 Lactobacillus acidophilus NCFM ABC transporter permease YP_194672.1 1851387 R 272621 CDS YP_194673.1 58338088 3251728 complement(1852449..1852976) 1 NC_006814.3 family; TetRAcrR; transcriptional regulator 1852976 3251728 LBA1840 Lactobacillus acidophilus NCFM transcriptional regulator YP_194673.1 1852449 R 272621 CDS YP_194674.1 58338089 3251729 complement(1853095..1853694) 1 NC_006814.3 COG0406 Fructose-2,6-bisphosphatase; phosphoglycerate mutase 1853694 3251729 LBA1841 Lactobacillus acidophilus NCFM phosphoglycerate mutase YP_194674.1 1853095 R 272621 CDS YP_194675.1 58338090 3251731 1853837..1854580 1 NC_006814.3 alpha/beta hydrolase 1854580 3251731 LBA1842 Lactobacillus acidophilus NCFM alpha/beta hydrolase YP_194675.1 1853837 D 272621 CDS YP_194676.1 58338091 3251732 complement(1854577..1855338) 1 NC_006814.3 hypothetical protein 1855338 3251732 LBA1843 Lactobacillus acidophilus NCFM hypothetical protein YP_194676.1 1854577 R 272621 CDS YP_194677.1 58338092 3251734 1855396..1856037 1 NC_006814.3 hypothetical protein 1856037 3251734 LBA1844 Lactobacillus acidophilus NCFM hypothetical protein YP_194677.1 1855396 D 272621 CDS YP_194678.1 58338093 3251736 complement(1856066..1856860) 1 NC_006814.3 COG1085 Galactose-1-phosphate uridylyltransferase; di-tripeptide transporter 1856860 3251736 LBA1845 Lactobacillus acidophilus NCFM di-tripeptide transporter YP_194678.1 1856066 R 272621 CDS YP_194679.1 58338094 3251738 1857013..1858221 1 NC_006814.3 hypothetical protein 1858221 3251738 LBA1846 Lactobacillus acidophilus NCFM hypothetical protein YP_194679.1 1857013 D 272621 CDS YP_194680.1 58338095 3251739 1858310..1858507 1 NC_006814.3 CG7497-PA; hypothetical protein 1858507 3251739 LBA1847 Lactobacillus acidophilus NCFM hypothetical protein YP_194680.1 1858310 D 272621 CDS YP_194681.1 58338096 3251742 complement(1858540..1860033) 1 NC_006814.3 di-tripeptide transport protein; di-tripeptide transporter 1860033 dtpT 3251742 dtpT Lactobacillus acidophilus NCFM di-tripeptide transporter YP_194681.1 1858540 R 272621 CDS YP_194682.1 58338097 3251744 complement(1860145..1862679) 1 NC_006814.3 aminopeptidase 1862679 pepN 3251744 pepN Lactobacillus acidophilus NCFM aminopeptidase YP_194682.1 1860145 R 272621 CDS YP_194683.1 58338098 3251747 1862891..1863253 1 NC_006814.3 LysM; extracellular protein; aggregation promoting protein 1863253 lysM 3251747 lysM Lactobacillus acidophilus NCFM aggregation promoting protein YP_194683.1 1862891 D 272621 CDS YP_194684.1 58338099 3251749 complement(1863331..1863426) 1 NC_006814.3 hypothetical protein 1863426 3251749 LBA1851 Lactobacillus acidophilus NCFM hypothetical protein YP_194684.1 1863331 R 272621 CDS YP_194685.1 58338100 3251748 complement(1863401..1864384) 1 NC_006814.3 d-ala,d-ala ligase 1864384 3251748 LBA1852 Lactobacillus acidophilus NCFM d-ala,d-ala ligase YP_194685.1 1863401 R 272621 CDS YP_194688.1 58338103 3251756 1866260..1867381 1 NC_006814.3 integral membrane protein; hypothetical protein 1867381 3251756 LBA1857 Lactobacillus acidophilus NCFM hypothetical protein YP_194688.1 1866260 D 272621 CDS YP_194689.1 58338104 3251758 complement(1867402..1867908) 1 NC_006814.3 hypothetical protein 1867908 3251758 LBA1858 Lactobacillus acidophilus NCFM hypothetical protein YP_194689.1 1867402 R 272621 CDS YP_194690.1 58338105 3251760 complement(1868004..1869767) 1 NC_006814.3 nisin transport protein 1869767 nisT 3251760 nisT Lactobacillus acidophilus NCFM nisin transport protein YP_194690.1 1868004 R 272621 CDS YP_194691.1 58338106 3251762 complement(1869803..1870012) 1 NC_006814.3 UTP-glucose-1-phosphate uridyltransferase; hypothetical protein 1870012 3251762 LBA1860 Lactobacillus acidophilus NCFM hypothetical protein YP_194691.1 1869803 R 272621 CDS YP_194692.1 58338107 3251763 complement(1870301..1870426) 1 NC_006814.3 hypothetical protein 1870426 3251763 LBA1861 Lactobacillus acidophilus NCFM hypothetical protein YP_194692.1 1870301 R 272621 CDS YP_194693.1 58338108 3251765 complement(1870586..1871404) 1 NC_006814.3 COG1396 Predicted transcriptional regulators; hypothetical protein 1871404 3251765 LBA1862 Lactobacillus acidophilus NCFM hypothetical protein YP_194693.1 1870586 R 272621 CDS YP_194694.1 58338109 3251767 complement(1871837..1872328) 1 NC_006814.3 COG1396 Predicted transcriptional regulators; transcriptional regulator 1872328 3251767 LBA1863 Lactobacillus acidophilus NCFM transcriptional regulator YP_194694.1 1871837 R 272621 CDS YP_194695.1 58338110 3251771 complement(1872452..1873309) 1 NC_006814.3 maltose ABC transporter permease 1873309 3251771 LBA1864 Lactobacillus acidophilus NCFM maltose ABC transporter permease YP_194695.1 1872452 R 272621 CDS YP_194696.1 58338111 3251773 complement(1873312..1874670) 1 NC_006814.3 maltose ABC transporter permease 1874670 3251773 LBA1865 Lactobacillus acidophilus NCFM maltose ABC transporter permease YP_194696.1 1873312 R 272621 CDS YP_194697.1 58338112 3251775 complement(1874741..1875967) 1 NC_006814.3 maltose ABC transporter permease 1875967 3251775 LBA1866 Lactobacillus acidophilus NCFM maltose ABC transporter permease YP_194697.1 1874741 R 272621 CDS YP_194698.1 58338113 3251776 complement(1876054..1877160) 1 NC_006814.3 MsmK; multiple sugar-binding ABC transport system 1877160 msmK 3251776 msmK Lactobacillus acidophilus NCFM multiple sugar-binding ABC transport system YP_194698.1 1876054 R 272621 CDS YP_194699.1 58338114 3251778 1877209..1878591 1 NC_006814.3 transposase 1878591 3251778 LBA1868 Lactobacillus acidophilus NCFM transposase YP_194699.1 1877209 D 272621 CDS YP_194700.1 58338115 3251780 complement(1878649..1879314) 1 NC_006814.3 COG0637 Predicted phosphatase-phosphohexomutase; beta-phosphoglucomutase 1879314 pgmB 3251780 pgmB Lactobacillus acidophilus NCFM beta-phosphoglucomutase YP_194700.1 1878649 R 272621 CDS YP_194701.1 58338116 3251782 complement(1879299..1881569) 1 NC_006814.3 maltose phosphorylase 1881569 3251782 LBA1870 Lactobacillus acidophilus NCFM maltose phosphorylase YP_194701.1 1879299 R 272621 CDS YP_194702.1 58338117 3251783 complement(1881740..1883461) 1 NC_006814.3 COG0366 Glycosidases; neopullulanase 1883461 3251783 LBA1871 Lactobacillus acidophilus NCFM neopullulanase YP_194702.1 1881740 R 272621 CDS YP_194703.1 58338118 3251785 complement(1883465..1885120) 1 NC_006814.3 COG0366 Glycosidases; oligo-1,6-glucosidase 1885120 3251785 LBA1872 Lactobacillus acidophilus NCFM oligo-1,6-glucosidase YP_194703.1 1883465 R 272621 CDS YP_194704.1 58338119 3251787 complement(1885232..1886407) 1 NC_006814.3 COG0282 Acetate kinase; acetate kinase 1886407 ackA 3251787 ackA Lactobacillus acidophilus NCFM acetate kinase YP_194704.1 1885232 R 272621 CDS YP_194705.1 58338120 3251789 complement(1886548..1887498) 1 NC_006814.3 LacI; COG1609 transcriptional regulators; transcriptional regulator family protein 1887498 3251789 LBA1874 Lactobacillus acidophilus NCFM transcriptional regulator family protein YP_194705.1 1886548 R 272621 CDS YP_194706.1 58338121 3251791 complement(1887507..1888280) 1 NC_006814.3 COG2365 protein tyrosine-serine phosphatase; protein-tyrosine-phosphatase 1888280 3251791 LBA1875 Lactobacillus acidophilus NCFM protein-tyrosine-phosphatase YP_194706.1 1887507 R 272621 CDS YP_194707.1 58338122 3251792 complement(1888369..1889949) 1 NC_006814.3 ABC transporter ATP-binding protein 1889949 3251792 LBA1876 Lactobacillus acidophilus NCFM ABC transporter ATP-binding protein YP_194707.1 1888369 R 272621 CDS YP_194708.1 58338123 3251795 complement(1890173..1890607) 1 NC_006814.3 COG1396 Predicted transcriptional regulators; hypothetical protein 1890607 3251795 LBA1877 Lactobacillus acidophilus NCFM hypothetical protein YP_194708.1 1890173 R 272621 CDS YP_194709.1 58338124 3251798 complement(1890996..1892498) 1 NC_006814.3 Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 1892498 glpK 3251798 glpK Lactobacillus acidophilus NCFM glycerol kinase YP_194709.1 1890996 R 272621 CDS YP_194710.1 58338125 3251801 1892629..1893447 1 NC_006814.3 phosphomethylpyrimidine kinase 1893447 thiD 3251801 thiD Lactobacillus acidophilus NCFM phosphomethylpyrimidine kinase YP_194710.1 1892629 D 272621 CDS YP_194711.1 58338126 3251802 complement(1893511..1893903) 1 NC_006814.3 hypothetical protein 1893903 3251802 LBA1880 Lactobacillus acidophilus NCFM hypothetical protein YP_194711.1 1893511 R 272621 CDS YP_194712.1 58338127 3251805 1894064..1894957 1 NC_006814.3 transposase 1894957 3251805 LBA1881 Lactobacillus acidophilus NCFM transposase YP_194712.1 1894064 D 272621 CDS YP_194713.1 58338128 3251807 1895242..1895928 1 NC_006814.3 CobQ; COG3442 Predicted glutamine amidotransferase; cobyric acid synthase 1895928 cobQ 3251807 cobQ Lactobacillus acidophilus NCFM cobyric acid synthase YP_194713.1 1895242 D 272621 CDS YP_194714.1 58338129 3251809 complement(1895988..1896470) 1 NC_006814.3 conserved hypothetical protein; NLP-P60 family secreted protein 1896470 3251809 LBA1883 Lactobacillus acidophilus NCFM NLP-P60 family secreted protein YP_194714.1 1895988 R 272621 CDS YP_194715.1 58338130 3251810 complement(1896636..1897556) 1 NC_006814.3 permease 1897556 3251810 LBA1884 Lactobacillus acidophilus NCFM permease YP_194715.1 1896636 R 272621 CDS YP_194716.1 58338131 3251812 complement(1897537..1898466) 1 NC_006814.3 permease 1898466 3251812 LBA1885 Lactobacillus acidophilus NCFM permease YP_194716.1 1897537 R 272621 CDS YP_194717.1 58338132 3251815 complement(1898545..1899447) 1 NC_006814.3 transport protein; permease 1899447 3251815 LBA1887 Lactobacillus acidophilus NCFM permease YP_194717.1 1898545 R 272621 CDS YP_194718.1 58338133 3251816 complement(1899519..1900160) 1 NC_006814.3 hypothetical protein 1900160 3251816 LBA1889 Lactobacillus acidophilus NCFM hypothetical protein YP_194718.1 1899519 R 272621 CDS YP_194719.1 58338134 3251818 complement(1900276..1900635) 1 NC_006814.3 COG0845 Membrane-fusion protein; hypothetical protein 1900635 3251818 LBA1890 Lactobacillus acidophilus NCFM hypothetical protein YP_194719.1 1900276 R 272621 CDS YP_194720.1 58338135 3251819 complement(1900707..1902002) 1 NC_006814.3 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 1902002 purB 3251819 purB Lactobacillus acidophilus NCFM adenylosuccinate lyase YP_194720.1 1900707 R 272621 CDS YP_194721.1 58338136 3251821 complement(1902006..1903295) 1 NC_006814.3 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 1903295 purA 3251821 purA Lactobacillus acidophilus NCFM adenylosuccinate synthetase YP_194721.1 1902006 R 272621 CDS YP_194722.1 58338137 3251822 1903494..1904486 1 NC_006814.3 COG0516 IMP dehydrogenase-GMP reductase; guanosine 5'-monophosphate oxidoreductase 1904486 3251822 LBA1893 Lactobacillus acidophilus NCFM guanosine 5'-monophosphate oxidoreductase YP_194722.1 1903494 D 272621 CDS YP_194723.1 58338138 3251824 complement(1904521..1904622) 1 NC_006814.3 hypothetical protein 1904622 3251824 LBA1894 Lactobacillus acidophilus NCFM hypothetical protein YP_194723.1 1904521 R 272621 CDS YP_194724.1 58338139 3251829 complement(1904930..1905988) 1 NC_006814.3 hypothetical protein 1905988 3251829 LBA1895 Lactobacillus acidophilus NCFM hypothetical protein YP_194724.1 1904930 R 272621 CDS YP_194725.1 58338140 3251832 1906422..1907432 1 NC_006814.3 catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 1907432 asnA 3251832 asnA Lactobacillus acidophilus NCFM asparagine synthetase AsnA YP_194725.1 1906422 D 272621 CDS YP_194726.1 58338141 3251834 complement(1907591..1908244) 1 NC_006814.3 FrnE; protein-disulfide isomerase 1908244 frnE 3251834 frnE Lactobacillus acidophilus NCFM protein-disulfide isomerase YP_194726.1 1907591 R 272621 CDS YP_194727.1 58338142 3251836 complement(1908267..1909199) 1 NC_006814.3 thioredoxin reductase 1909199 trxR 3251836 trxR Lactobacillus acidophilus NCFM thioredoxin reductase YP_194727.1 1908267 R 272621 CDS YP_194728.1 58338143 3251838 complement(1909222..1909884) 1 NC_006814.3 family; ArsR; COG0607 Rhodanese-related sulfurtransferase; transcriptional regulator 1909884 3251838 LBA1899 Lactobacillus acidophilus NCFM transcriptional regulator YP_194728.1 1909222 R 272621 CDS YP_194729.1 58338144 3251839 complement(1909868..1910011) 1 NC_006814.3 hypothetical protein 1910011 3251839 LBA1900 Lactobacillus acidophilus NCFM hypothetical protein YP_194729.1 1909868 R 272621 CDS YP_194730.1 58338145 3251841 complement(1910004..1910315) 1 NC_006814.3 thioredoxin 2; thioredoxin 1910315 3251841 LBA1901 Lactobacillus acidophilus NCFM thioredoxin YP_194730.1 1910004 R 272621 CDS YP_194731.1 58338146 3251842 complement(1910472..1911863) 1 NC_006814.3 COG0531 Amino acid transporters; amino acid permease 1911863 3251842 LBA1902 Lactobacillus acidophilus NCFM amino acid permease YP_194731.1 1910472 R 272621 CDS YP_194732.1 58338147 3251844 complement(1911877..1912605) 1 NC_006814.3 COG2071 Predicted glutamine amidotransferases; glutamine amidotransferase 1912605 3251844 LBA1903 Lactobacillus acidophilus NCFM glutamine amidotransferase YP_194732.1 1911877 R 272621 CDS YP_194733.1 58338148 3251846 complement(1912824..1914197) 1 NC_006814.3 YifK; amino acid permease 1914197 yifK 3251846 yifK Lactobacillus acidophilus NCFM amino acid permease YP_194733.1 1912824 R 272621 CDS YP_194734.1 58338149 3251847 complement(1914241..1915590) 1 NC_006814.3 AapA; amino acid permease 1915590 aapA 3251847 aapA Lactobacillus acidophilus NCFM amino acid permease YP_194734.1 1914241 R 272621 CDS YP_194735.1 58338150 3251849 complement(1915704..1916570) 1 NC_006814.3 hypothetical protein 1916570 3251849 LBA1906 Lactobacillus acidophilus NCFM hypothetical protein YP_194735.1 1915704 R 272621 CDS YP_194736.1 58338151 3251851 1916650..1918158 1 NC_006814.3 transposase 1918158 3251851 LBA1907 Lactobacillus acidophilus NCFM transposase YP_194736.1 1916650 D 272621 CDS YP_194737.1 58338152 3251852 1918204..1918314 1 NC_006814.3 hypothetical protein 1918314 3251852 LBA1908 Lactobacillus acidophilus NCFM hypothetical protein YP_194737.1 1918204 D 272621 CDS YP_194738.1 58338153 3251854 complement(1918337..1918969) 1 NC_006814.3 COG0681 Signal peptidase I; signal peptidase I 1918969 3251854 LBA1909 Lactobacillus acidophilus NCFM signal peptidase I YP_194738.1 1918337 R 272621 CDS YP_194739.1 58338154 3251855 complement(1919088..1921217) 1 NC_006814.3 ClpE; ATP-dependent protease 1921217 clpE 3251855 clpE Lactobacillus acidophilus NCFM ATP-dependent protease YP_194739.1 1919088 R 272621 CDS YP_194740.1 58338155 3251857 complement(1921535..1922446) 1 NC_006814.3 cell surface hydrolase 1922446 3251857 LBA1911 Lactobacillus acidophilus NCFM cell surface hydrolase YP_194740.1 1921535 R 272621 CDS YP_194741.1 58338156 3251859 complement(1922427..1923737) 1 NC_006814.3 PTS system cellobiose-specific transporter subunit IIC 1923737 3251859 LBA1912 Lactobacillus acidophilus NCFM PTS system cellobiose-specific transporter subunit IIC YP_194741.1 1922427 R 272621 CDS YP_194742.1 58338157 3251861 1923826..1924527 1 NC_006814.3 ABC transporter ATPase 1924527 3251861 LBA1913 Lactobacillus acidophilus NCFM ABC transporter ATPase YP_194742.1 1923826 D 272621 CDS YP_194743.1 58338158 3251863 1924528..1927068 1 NC_006814.3 ABC transporter permease 1927068 3251863 LBA1914 Lactobacillus acidophilus NCFM ABC transporter permease YP_194743.1 1924528 D 272621 CDS YP_194744.1 58338159 3251865 1927105..1927341 1 NC_006814.3 hypothetical protein 1927341 3251865 LBA1915 Lactobacillus acidophilus NCFM hypothetical protein YP_194744.1 1927105 D 272621 CDS YP_194745.1 58338160 3251867 complement(1927385..1929001) 1 NC_006814.3 polysaccharide biosynthesis family protein; polysaccharide transporter 1929001 3251867 LBA1917 Lactobacillus acidophilus NCFM polysaccharide transporter YP_194745.1 1927385 R 272621 CDS YP_194746.1 58338161 3251869 1929296..1930267 1 NC_006814.3 LysA; lysin; lysin 1930267 lysA 3251869 lysA Lactobacillus acidophilus NCFM lysin YP_194746.1 1929296 D 272621 CDS YP_194747.1 58338162 3251871 complement(1930324..1931001) 1 NC_006814.3 hypothetical protein 1931001 3251871 LBA1919 Lactobacillus acidophilus NCFM hypothetical protein YP_194747.1 1930324 R 272621 CDS YP_194748.1 58338163 3251874 complement(1931444..1931632) 1 NC_006814.3 hypothetical protein 1931632 3251874 LBA1920 Lactobacillus acidophilus NCFM hypothetical protein YP_194748.1 1931444 R 272621 CDS YP_194749.1 58338164 3251875 complement(1931692..1932063) 1 NC_006814.3 COG3247 Uncharacterized conserved protein; hypothetical protein 1932063 3251875 LBA1921 Lactobacillus acidophilus NCFM hypothetical protein YP_194749.1 1931692 R 272621 CDS YP_194750.1 58338165 3251877 complement(1932187..1933128) 1 NC_006814.3 penicillin-binding protein 1933128 3251877 LBA1922 Lactobacillus acidophilus NCFM penicillin-binding protein YP_194750.1 1932187 R 272621 CDS YP_194751.1 58338166 3251878 complement(1933128..1934414) 1 NC_006814.3 DltD; COG3966 protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid; hypothetical protein 1934414 dltD 3251878 dltD Lactobacillus acidophilus NCFM hypothetical protein YP_194751.1 1933128 R 272621 CDS YP_194752.1 58338167 3251879 complement(1934407..1934646) 1 NC_006814.3 D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 2 1934646 dltC 3251879 dltC Lactobacillus acidophilus NCFM D-alanine--poly(phosphoribitol) ligase subunit 2 YP_194752.1 1934407 R 272621 CDS YP_194753.1 58338168 3251314 complement(1934681..1935919) 1 NC_006814.3 DltB; membrane protein 1935919 dltB 3251314 dltB Lactobacillus acidophilus NCFM membrane protein YP_194753.1 1934681 R 272621 CDS YP_194754.1 58338169 3251316 complement(1935919..1937433) 1 NC_006814.3 transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 1 1937433 dltA 3251316 dltA Lactobacillus acidophilus NCFM D-alanine--poly(phosphoribitol) ligase subunit 1 YP_194754.1 1935919 R 272621 CDS YP_194755.1 58338170 3251317 complement(1938062..1939198) 1 NC_006814.3 hypothetical protein 1939198 3251317 LBA1927 Lactobacillus acidophilus NCFM hypothetical protein YP_194755.1 1938062 R 272621 CDS YP_194756.1 58338171 3251881 1939798..1940274 1 NC_006814.3 COG0517 FOG CBS domain; hypothetical protein 1940274 3251881 LBA1928 Lactobacillus acidophilus NCFM hypothetical protein YP_194756.1 1939798 D 272621 CDS YP_194757.1 58338172 3251883 1940395..1942251 1 NC_006814.3 COG2217 Cation transport ATPase; cadmium efflux ATPase 1942251 3251883 LBA1929 Lactobacillus acidophilus NCFM cadmium efflux ATPase YP_194757.1 1940395 D 272621 CDS YP_194758.1 58338173 3251885 1942398..1943567 1 NC_006814.3 Na-H antiporter 1943567 3251885 LBA1931 Lactobacillus acidophilus NCFM Na-H antiporter YP_194758.1 1942398 D 272621 CDS YP_194759.1 58338174 3251886 complement(1943856..1944503) 1 NC_006814.3 COG3595 Uncharacterized conserved protein; hypothetical protein 1944503 3251886 LBA1932 Lactobacillus acidophilus NCFM hypothetical protein YP_194759.1 1943856 R 272621 CDS YP_194760.1 58338175 3251887 complement(1944559..1946121) 1 NC_006814.3 MutT; ABC transporter ATP-binding protein/permease 1946121 mutT 3251887 mutT Lactobacillus acidophilus NCFM ABC transporter ATP-binding protein/permease YP_194760.1 1944559 R 272621 CDS YP_194761.1 58338176 3251890 1946226..1947074 1 NC_006814.3 MutR; hypothetical protein; transcriptional regulator 1947074 mutR 3251890 mutR Lactobacillus acidophilus NCFM transcriptional regulator YP_194761.1 1946226 D 272621 CDS YP_194762.1 58338177 3251892 1947131..1947745 1 NC_006814.3 phage capsid protein 1947745 3251892 LBA1935 Lactobacillus acidophilus NCFM phage capsid protein YP_194762.1 1947131 D 272621 CDS YP_194763.1 58338178 3251893 1947726..1948250 1 NC_006814.3 COG1396 Predicted transcriptional regulators; hypothetical protein 1948250 3251893 LBA1936 Lactobacillus acidophilus NCFM hypothetical protein YP_194763.1 1947726 D 272621 CDS YP_194764.1 58338179 3251894 complement(1948290..1948943) 1 NC_006814.3 hypothetical protein 1948943 3251894 LBA1937 Lactobacillus acidophilus NCFM hypothetical protein YP_194764.1 1948290 R 272621 CDS YP_194765.1 58338180 3251896 1949031..1950134 1 NC_006814.3 COG1434 Uncharacterized conserved protein; hypothetical protein 1950134 3251896 LBA1938 Lactobacillus acidophilus NCFM hypothetical protein YP_194765.1 1949031 D 272621 CDS YP_194766.1 58338181 3251897 1950153..1952492 1 NC_006814.3 ABC transporter ATP-binding protein 1952492 3251897 LBA1939 Lactobacillus acidophilus NCFM ABC transporter ATP-binding protein YP_194766.1 1950153 D 272621 CDS YP_194767.1 58338182 3251899 complement(1952531..1953136) 1 NC_006814.3 COG4684 Predicted membrane protein; hypothetical protein 1953136 3251899 LBA1940 Lactobacillus acidophilus NCFM hypothetical protein YP_194767.1 1952531 R 272621 CDS YP_194768.1 58338183 3251901 1953232..1954293 1 NC_006814.3 hypothetical protein 1954293 3251901 LBA1942 Lactobacillus acidophilus NCFM hypothetical protein YP_194768.1 1953232 D 272621 CDS YP_194769.1 58338184 3251903 1954506..1955591 1 NC_006814.3 lipoprotein 1955591 3251903 LBA1943 Lactobacillus acidophilus NCFM lipoprotein YP_194769.1 1954506 D 272621 CDS YP_194770.1 58338185 3251906 1955658..1957196 1 NC_006814.3 sugar ABC transporter ATP binding protein 1957196 3251906 LBA1944 Lactobacillus acidophilus NCFM sugar ABC transporter ATP binding protein YP_194770.1 1955658 D 272621 CDS YP_194771.1 58338186 3251907 1957189..1958340 1 NC_006814.3 sugar ABC transporter permease 1958340 3251907 LBA1945 Lactobacillus acidophilus NCFM sugar ABC transporter permease YP_194771.1 1957189 D 272621 CDS YP_194772.1 58338187 3251908 1958341..1959297 1 NC_006814.3 sugar ABC transporter permease 1959297 3251908 LBA1946 Lactobacillus acidophilus NCFM sugar ABC transporter permease YP_194772.1 1958341 D 272621 CDS YP_194773.1 58338188 3251910 complement(1959404..1960231) 1 NC_006814.3 aldehyde reductase 1960231 3251910 LBA1947 Lactobacillus acidophilus NCFM aldehyde reductase YP_194773.1 1959404 R 272621 CDS YP_194774.1 58338189 3251912 1960351..1961070 1 NC_006814.3 glucosamine-6-phosphate isomerase 1961070 3251912 LBA1948 Lactobacillus acidophilus NCFM glucosamine-6-phosphate isomerase YP_194774.1 1960351 D 272621 CDS YP_194775.1 58338190 3251913 1961249..1961896 1 NC_006814.3 COG1428 Deoxynucleoside kinases; deoxyadenosine kinase 1961896 3251913 LBA1949 Lactobacillus acidophilus NCFM deoxyadenosine kinase YP_194775.1 1961249 D 272621 CDS YP_194776.1 58338191 3251915 1961922..1962608 1 NC_006814.3 COG1428 Deoxynucleoside kinases; deoxyguanosine kinase 1962608 3251915 LBA1950 Lactobacillus acidophilus NCFM deoxyguanosine kinase YP_194776.1 1961922 D 272621 CDS YP_194777.1 58338192 3251917 complement(1962667..1963467) 1 NC_006814.3 hypothetical protein 1963467 3251917 LBA1951 Lactobacillus acidophilus NCFM hypothetical protein YP_194777.1 1962667 R 272621 CDS YP_194778.1 58338193 3251919 1963692..1964999 1 NC_006814.3 xanthine-uracil permeases family protein; xanthine-uracil permeases 1964999 3251919 LBA1952 Lactobacillus acidophilus NCFM xanthine-uracil permeases YP_194778.1 1963692 D 272621 CDS YP_194779.1 58338194 3251921 1965072..1966097 1 NC_006814.3 transposase 1966097 3251921 LBA1954 Lactobacillus acidophilus NCFM transposase YP_194779.1 1965072 D 272621 CDS YP_194780.1 58338195 3251922 complement(1966662..1967393) 1 NC_006814.3 MerR; transcriptional activator; transcriptional regulator family protein 1967393 3251922 LBA1955 Lactobacillus acidophilus NCFM transcriptional regulator family protein YP_194780.1 1966662 R 272621 CDS YP_194781.1 58338196 3251924 1967573..1968829 1 NC_006814.3 COG2252 Permeases; xanthine-uracil permeases family protein 1968829 3251924 LBA1956 Lactobacillus acidophilus NCFM xanthine-uracil permeases family protein YP_194781.1 1967573 D 272621 CDS YP_194782.1 58338197 3251925 1969365..1970264 1 NC_006814.3 prolyl aminopeptidase 1970264 pepL 3251925 pepL Lactobacillus acidophilus NCFM prolyl aminopeptidase YP_194782.1 1969365 D 272621 CDS YP_194783.1 58338198 3251927 1970268..1971893 1 NC_006814.3 OppA; oligopeptide ABC transporter substrate binding protein 1971893 oppA 3251927 oppA Lactobacillus acidophilus NCFM oligopeptide ABC transporter substrate binding protein YP_194783.1 1970268 D 272621 CDS YP_194786.1 58338201 3251932 1974129..1975757 1 NC_006814.3 oligopeptide ABC transporter substrate binding protein 1975757 oppA 3251932 oppA Lactobacillus acidophilus NCFM oligopeptide ABC transporter substrate binding protein YP_194786.1 1974129 D 272621 CDS YP_194787.1 58338202 3251935 1975860..1976300 1 NC_006814.3 the negative regulator of copYZAB operon 1976300 atkY 3251935 atkY Lactobacillus acidophilus NCFM the negative regulator of copYZAB operon YP_194787.1 1975860 D 272621 CDS YP_194788.1 58338203 3251936 1976310..1976687 1 NC_006814.3 hypothetical protein 1976687 3251936 LBA1964 Lactobacillus acidophilus NCFM hypothetical protein YP_194788.1 1976310 D 272621 CDS YP_194789.1 58338204 3251938 1976687..1976974 1 NC_006814.3 COG4633 Uncharacterized protein conserved in bacteria; hypothetical protein 1976974 3251938 LBA1965 Lactobacillus acidophilus NCFM hypothetical protein YP_194789.1 1976687 D 272621 CDS YP_194790.1 58338205 3251939 1976974..1978899 1 NC_006814.3 COG2217 Cation transport ATPase; copper-transporting ATPase 1978899 copA 3251939 copA Lactobacillus acidophilus NCFM copper-transporting ATPase YP_194790.1 1976974 D 272621 CDS YP_194791.1 58338206 3251942 1978991..1980043 1 NC_006814.3 COG1434 Uncharacterized conserved protein; hypothetical protein 1980043 gdmH 3251942 gdmH Lactobacillus acidophilus NCFM hypothetical protein YP_194791.1 1978991 D 272621 CDS YP_194792.1 58338207 3251943 complement(1980045..1980758) 1 NC_006814.3 hypothetical protein 1980758 3251943 LBA1968 Lactobacillus acidophilus NCFM hypothetical protein YP_194792.1 1980045 R 272621 CDS YP_194793.1 58338208 3251944 complement(1980774..1981427) 1 NC_006814.3 FlpA; COG0664 cAMP-binding protein -catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases; FNR-like transcriptional regulator 1981427 flpA 3251944 flpA Lactobacillus acidophilus NCFM FNR-like transcriptional regulator YP_194793.1 1980774 R 272621 CDS YP_194794.1 58338209 3251946 complement(1981490..1981639) 1 NC_006814.3 hypothetical protein 1981639 3251946 LBA1970 Lactobacillus acidophilus NCFM hypothetical protein YP_194794.1 1981490 R 272621 CDS YP_194795.1 58338210 3251948 complement(1981700..1982803) 1 NC_006814.3 COG0498 Threonine synthase; hypothetical protein 1982803 3251948 LBA1971 Lactobacillus acidophilus NCFM hypothetical protein YP_194795.1 1981700 R 272621 CDS YP_194796.1 58338211 3251949 complement(1982831..1984390) 1 NC_006814.3 voltage-gated chloride channel family protein 1984390 yadQ 3251949 yadQ Lactobacillus acidophilus NCFM voltage-gated chloride channel family protein YP_194796.1 1982831 R 272621 CDS YP_194797.1 58338212 3251952 complement(1984485..1985888) 1 NC_006814.3 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 1985888 3251952 LBA1973 Lactobacillus acidophilus NCFM 6-phosphogluconate dehydrogenase YP_194797.1 1984485 R 272621 CDS YP_194798.1 58338213 3251954 complement(1986105..1987910) 1 NC_006814.3 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome); pyruvate oxidase 1987910 poxB 3251954 poxB Lactobacillus acidophilus NCFM pyruvate oxidase YP_194798.1 1986105 R 272621 CDS YP_194799.1 58338214 3251956 complement(1988269..1990167) 1 NC_006814.3 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 1990167 gidA 3251956 gidA Lactobacillus acidophilus NCFM tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_194799.1 1988269 R 272621 CDS YP_194800.1 58338215 3251958 complement(1990180..1991565) 1 NC_006814.3 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 1991565 trmE 3251958 trmE Lactobacillus acidophilus NCFM tRNA modification GTPase TrmE YP_194800.1 1990180 R 272621 CDS YP_194801.1 58338216 3251960 complement(1991677..1992552) 1 NC_006814.3 stage III sporulation protein J 1992552 3251960 LBA1977 Lactobacillus acidophilus NCFM stage III sporulation protein J YP_194801.1 1991677 R 272621 CDS YP_194802.1 58338217 3251962 complement(1992554..1992922) 1 NC_006814.3 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 1992922 rnpA 3251962 rnpA Lactobacillus acidophilus NCFM ribonuclease P YP_194802.1 1992554 R 272621 CDS YP_194803.1 58338218 3251963 complement(1992974..1993114) 1 NC_006814.3 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 1993114 rpmH 3251963 rpmH Lactobacillus acidophilus NCFM 50S ribosomal protein L34 YP_194803.1 1992974 R 272621 CDS