-- dump date   	20140619_122445
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
695560000001	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
695560000002	DnaA N-terminal domain; Region: DnaA_N; pfam11638
695560000003	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
695560000004	Walker A motif; other site
695560000005	ATP binding site [chemical binding]; other site
695560000006	Walker B motif; other site
695560000007	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
695560000008	arginine finger; other site
695560000009	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
695560000010	DnaA box-binding interface [nucleotide binding]; other site
695560000011	DNA polymerase III subunit beta; Validated; Region: PRK05643
695560000012	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
695560000013	putative DNA binding surface [nucleotide binding]; other site
695560000014	dimer interface [polypeptide binding]; other site
695560000015	beta-clamp/clamp loader binding surface; other site
695560000016	beta-clamp/translesion DNA polymerase binding surface; other site
695560000017	S4 domain; Region: S4_2; pfam13275
695560000018	recombination protein F; Reviewed; Region: recF; PRK00064
695560000019	ATP-binding cassette domain of RecF; Region: ABC_RecF; cd03242
695560000020	Walker A/P-loop; other site
695560000021	ATP binding site [chemical binding]; other site
695560000022	Q-loop/lid; other site
695560000023	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
695560000024	ABC transporter signature motif; other site
695560000025	Walker B; other site
695560000026	D-loop; other site
695560000027	H-loop/switch region; other site
695560000028	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
695560000029	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
695560000030	Mg2+ binding site [ion binding]; other site
695560000031	G-X-G motif; other site
695560000032	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
695560000033	anchoring element; other site
695560000034	dimer interface [polypeptide binding]; other site
695560000035	ATP binding site [chemical binding]; other site
695560000036	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
695560000037	active site
695560000038	putative metal-binding site [ion binding]; other site
695560000039	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
695560000040	DNA gyrase subunit A; Validated; Region: PRK05560
695560000041	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
695560000042	CAP-like domain; other site
695560000043	active site
695560000044	primary dimer interface [polypeptide binding]; other site
695560000045	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
695560000046	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
695560000047	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
695560000048	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
695560000049	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
695560000050	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
695560000051	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
695560000052	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
695560000053	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
695560000054	dimer interface [polypeptide binding]; other site
695560000055	ssDNA binding site [nucleotide binding]; other site
695560000056	tetramer (dimer of dimers) interface [polypeptide binding]; other site
695560000057	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
695560000058	Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain [Signal transduction mechanisms]; Region: COG3887
695560000059	Class III nucleotidyl cyclases; Region: Nucleotidyl_cyc_III; cl11967
695560000060	DHH family; Region: DHH; pfam01368
695560000061	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
695560000062	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
695560000063	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
695560000064	replicative DNA helicase; Region: DnaB; TIGR00665
695560000065	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
695560000066	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
695560000067	Walker A motif; other site
695560000068	ATP binding site [chemical binding]; other site
695560000069	Walker B motif; other site
695560000070	DNA binding loops [nucleotide binding]
695560000071	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; pfam12974
695560000072	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
695560000073	substrate binding pocket [chemical binding]; other site
695560000074	membrane-bound complex binding site; other site
695560000075	hinge residues; other site
695560000076	EDD domain protein, DegV family; Region: DegV; TIGR00762
695560000077	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
695560000078	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
695560000079	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
695560000080	nucleotide binding site [chemical binding]; other site
695560000081	Predicted membrane protein [Function unknown]; Region: COG2261
695560000082	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
695560000083	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
695560000084	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
695560000085	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
695560000086	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
695560000087	non-specific DNA binding site [nucleotide binding]; other site
695560000088	salt bridge; other site
695560000089	sequence-specific DNA binding site [nucleotide binding]; other site
695560000090	Uncharacterized conserved protein [Function unknown]; Region: COG1944
695560000091	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
695560000092	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
695560000093	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
695560000094	Walker A/P-loop; other site
695560000095	ATP binding site [chemical binding]; other site
695560000096	Q-loop/lid; other site
695560000097	ABC transporter signature motif; other site
695560000098	Walker B; other site
695560000099	D-loop; other site
695560000100	H-loop/switch region; other site
695560000101	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
695560000102	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
695560000103	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
695560000104	Walker A/P-loop; other site
695560000105	ATP binding site [chemical binding]; other site
695560000106	Q-loop/lid; other site
695560000107	ABC transporter signature motif; other site
695560000108	Walker B; other site
695560000109	D-loop; other site
695560000110	H-loop/switch region; other site
695560000111	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
695560000112	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
695560000113	ABC transporter; Region: ABC_tran_2; pfam12848
695560000114	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
695560000115	lipoprotein releasing system, ATP-binding protein; Region: LolD_lipo_ex; TIGR02211
695560000116	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
695560000117	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
695560000118	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
695560000119	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
695560000120	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
695560000121	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
695560000122	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
695560000123	Protein of unknown function (DUF2974); Region: DUF2974; pfam11187
695560000124	putative Mg(2+) transport ATPase; Provisional; Region: PRK09977
695560000125	MgtC family; Region: MgtC; pfam02308
695560000126	Protein of unknown function (DUF3923); Region: DUF3923; pfam13061
695560000127	Aminoglycoside 3-N-acetyltransferase; Region: Antibiotic_NAT; pfam02522
695560000128	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
695560000129	putative trimer interface [polypeptide binding]; other site
695560000130	putative CoA binding site [chemical binding]; other site
695560000131	Restriction endonuclease; Region: Mrr_cat; pfam04471
695560000132	Peptidase family C69; Region: Peptidase_C69; pfam03577
695560000133	Gram positive anchor; Region: Gram_pos_anchor; pfam00746
695560000134	Predicted membrane protein [Function unknown]; Region: COG4905
695560000135	Protein of unknown function (DUF1113); Region: DUF1113; pfam06541
695560000136	Cobalamin adenosyltransferase; Region: Cob_adeno_trans; pfam01923
695560000137	ECF-type riboflavin transporter, S component; Region: ECF-ribofla_trS; cl17272
695560000138	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
695560000139	ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent; Region: RTPR; TIGR02505
695560000140	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
695560000141	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
695560000142	Domain of unknown function DUF20; Region: UPF0118; pfam01594
695560000143	Isoamyl-acetate hydrolyzing esterase-like proteins. SGNH_hydrolase subfamily similar to the Saccharomyces cerevisiae IAH1. IAH1 may be the major esterase that hydrolyses isoamyl acetate in sake mash.  The SGNH-family of hydrolases is a diverse family of...; Region: Isoamyl_acetate_hydrolase_like; cd01838
695560000144	catalytic triad [active]
695560000145	oxyanion hole [active]
695560000146	active site
695560000147	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
695560000148	putative substrate translocation pore; other site
695560000149	Major Facilitator Superfamily; Region: MFS_1; pfam07690
695560000150	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: PhnK; COG1101
695560000151	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
695560000152	Walker A/P-loop; other site
695560000153	ATP binding site [chemical binding]; other site
695560000154	Q-loop/lid; other site
695560000155	ABC transporter signature motif; other site
695560000156	Walker B; other site
695560000157	D-loop; other site
695560000158	H-loop/switch region; other site
695560000159	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cd06574
695560000160	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
695560000161	TM-ABC transporter signature motif; other site
695560000162	Type I periplasmic ligand-binding domain of uncharacterized ABC-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_uncharacterized_transporter; cd06325
695560000163	zinc binding site [ion binding]; other site
695560000164	putative ligand binding site [chemical binding]; other site
695560000165	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
695560000166	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
695560000167	motif II; other site
695560000168	Tet(M)-like family includes Tet(M), Tet(O), Tet(W), and OtrA, containing tetracycline resistant proteins; Region: TetM_like; cd04168
695560000169	Translation elongation factors (GTPases) [Translation, ribosomal structure and biogenesis]; Region: FusA; COG0480
695560000170	G1 box; other site
695560000171	putative GEF interaction site [polypeptide binding]; other site
695560000172	GTP/Mg2+ binding site [chemical binding]; other site
695560000173	Switch I region; other site
695560000174	G2 box; other site
695560000175	G3 box; other site
695560000176	Switch II region; other site
695560000177	G4 box; other site
695560000178	G5 box; other site
695560000179	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
695560000180	Elongation Factor G-like domain IV. This family includes the translational elongation factor termed EF-2 (for Archaea and Eukarya) and EF-G (for Bacteria), ribosomal protection proteins that mediate tetracycline resistance and, an evolutionarily...; Region: EFG_like_IV; cl02789
695560000181	Tet_C: C-terminus of ribosomal protection proteins Tet(M) and Tet(O). This domain has homology to the C terminal domains of the elongation factors EF-G and EF-2. Tet(M) and Tet(O) catalyze the release of tetracycline (Tc) from the ribosome in a...; Region: Tet_C; cd03711
695560000182	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
695560000183	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
695560000184	active site
695560000185	motif I; other site
695560000186	motif II; other site
695560000187	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
695560000188	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
695560000189	putative catalytic site [active]
695560000190	putative metal binding site [ion binding]; other site
695560000191	putative phosphate binding site [ion binding]; other site
695560000192	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
695560000193	catalytic core [active]
695560000194	D-lactate dehydrogenase; Validated; Region: PRK08605
695560000195	D-Lactate dehydrogenase and D-2-Hydroxyisocaproic acid dehydrogenase (D-HicDH), NAD-binding and catalytic domains; Region: LDH; cd12186
695560000196	homodimer interface [polypeptide binding]; other site
695560000197	ligand binding site [chemical binding]; other site
695560000198	NAD binding site [chemical binding]; other site
695560000199	catalytic site [active]
695560000200	Human Ape1-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Ape1-like_AP-endo; cd09087
695560000201	active site
695560000202	putative catalytic site [active]
695560000203	DNA binding site [nucleotide binding]
695560000204	putative phosphate binding site [ion binding]; other site
695560000205	metal binding site A [ion binding]; metal-binding site
695560000206	AP binding site [nucleotide binding]; other site
695560000207	metal binding site B [ion binding]; metal-binding site
695560000208	potential frameshift: common BLAST hit: gi|58336407|ref|YP_192992.1| glutamategamma-aminobutyrate antiporter
695560000209	potential frameshift: common BLAST hit: gi|295691917|ref|YP_003600527.1| Glutamate/gamma-aminobutyrate antiporter
695560000210	N-terminal putative catalytic domain of uncharacterized prokaryotic and archeal HKD family nucleases fused to a DEAD/DEAH box helicase domain; Region: PLDc_N_DEXD_b2; cd09204
695560000211	PLD-like domain; Region: PLDc_2; pfam13091
695560000212	putative homodimer interface [polypeptide binding]; other site
695560000213	putative active site [active]
695560000214	catalytic site [active]
695560000215	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
695560000216	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
695560000217	ATP binding site [chemical binding]; other site
695560000218	putative Mg++ binding site [ion binding]; other site
695560000219	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
695560000220	nucleotide binding region [chemical binding]; other site
695560000221	ATP-binding site [chemical binding]; other site
695560000222	Domain of unknown function (DUF3427); Region: DUF3427; pfam11907
695560000223	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
695560000224	Beta-lactamase; Region: Beta-lactamase; pfam00144
695560000225	Uncharacterized conserved protein (DUF2075); Region: DUF2075; pfam09848
695560000226	AAA ATPase domain; Region: AAA_16; pfam13191
695560000227	Uncharacterized conserved protein [Function unknown]; Region: COG3410
695560000228	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
695560000229	active site
695560000230	catalytic residues [active]
695560000231	metal binding site [ion binding]; metal-binding site
695560000232	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
695560000233	Transposase; Region: DDE_Tnp_ISL3; pfam01610
695560000234	Transcriptional regulator [Transcription]; Region: LysR; COG0583
695560000235	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
695560000236	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
695560000237	dimerization interface [polypeptide binding]; other site
695560000238	FMN-binding domain; Region: FMN_bind; pfam04205
695560000239	flavocytochrome c; Region: flavo_cyto_c; TIGR01813
695560000240	L-aspartate oxidase; Provisional; Region: PRK06175
695560000241	putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834
695560000242	Cytochrome b5-like Heme/Steroid binding domain; Region: Cyt-b5; cl02041
695560000243	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
695560000244	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
695560000245	putative acyl-acceptor binding pocket; other site
695560000246	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
695560000247	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
695560000248	Ligand binding site; other site
695560000249	metal-binding site
695560000250	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
695560000251	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
695560000252	Ligand binding site; other site
695560000253	metal-binding site
695560000254	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
695560000255	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
695560000256	active site
695560000257	Helix-turn-helix domain; Region: HTH_19; pfam12844
695560000258	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
695560000259	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
695560000260	non-specific DNA binding site [nucleotide binding]; other site
695560000261	salt bridge; other site
695560000262	sequence-specific DNA binding site [nucleotide binding]; other site
695560000263	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
695560000264	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
695560000265	putative acyl-acceptor binding pocket; other site
695560000266	transposase, putative, N-terminal domain; Region: tspaseT_teng_N; TIGR01765
695560000267	Probable transposase; Region: OrfB_IS605; pfam01385
695560000268	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
695560000269	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
695560000270	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
695560000271	Peptidase family M48; Region: Peptidase_M48; cl12018
695560000272	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
695560000273	non-specific DNA binding site [nucleotide binding]; other site
695560000274	salt bridge; other site
695560000275	sequence-specific DNA binding site [nucleotide binding]; other site
695560000276	Bacterial surface layer protein; Region: SLAP; pfam03217
695560000277	Peptidase family M48; Region: Peptidase_M48; cl12018
695560000278	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
695560000279	non-specific DNA binding site [nucleotide binding]; other site
695560000280	salt bridge; other site
695560000281	sequence-specific DNA binding site [nucleotide binding]; other site
695560000282	Bacterial surface layer protein; Region: SLAP; pfam03217
695560000283	Bacterial surface layer protein; Region: SLAP; pfam03217
695560000284	Bacterial surface layer protein; Region: SLAP; pfam03217
695560000285	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
695560000286	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
695560000287	active site
695560000288	phosphorylation site [posttranslational modification]
695560000289	intermolecular recognition site; other site
695560000290	dimerization interface [polypeptide binding]; other site
695560000291	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
695560000292	DNA binding site [nucleotide binding]
695560000293	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: VicK; COG5002
695560000294	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
695560000295	dimerization interface [polypeptide binding]; other site
695560000296	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
695560000297	putative active site [active]
695560000298	heme pocket [chemical binding]; other site
695560000299	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
695560000300	dimer interface [polypeptide binding]; other site
695560000301	phosphorylation site [posttranslational modification]
695560000302	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
695560000303	ATP binding site [chemical binding]; other site
695560000304	Mg2+ binding site [ion binding]; other site
695560000305	G-X-G motif; other site
695560000306	YycH protein; Region: YycH; pfam07435
695560000307	YycH protein; Region: YycI; pfam09648
695560000308	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
695560000309	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
695560000310	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
695560000311	protein binding site [polypeptide binding]; other site
695560000312	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
695560000313	galactoside O-acetyltransferase; Reviewed; Region: lacA; PRK09527
695560000314	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
695560000315	active site
695560000316	substrate binding site [chemical binding]; other site
695560000317	trimer interface [polypeptide binding]; other site
695560000318	CoA binding site [chemical binding]; other site
695560000319	proline-specific peptidase, Bacillus coagulans-type subfamily; Region: pro_imino_pep_2; TIGR01250
695560000320	Cobalt transport protein; Region: CbiQ; cl00463
695560000321	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
695560000322	Walker A/P-loop; other site
695560000323	ATP binding site [chemical binding]; other site
695560000324	ABC transporter; Region: ABC_tran; pfam00005
695560000325	Q-loop/lid; other site
695560000326	ABC transporter signature motif; other site
695560000327	Walker B; other site
695560000328	D-loop; other site
695560000329	H-loop/switch region; other site
695560000330	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
695560000331	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
695560000332	Walker A/P-loop; other site
695560000333	ATP binding site [chemical binding]; other site
695560000334	Q-loop/lid; other site
695560000335	ABC transporter signature motif; other site
695560000336	Walker B; other site
695560000337	D-loop; other site
695560000338	H-loop/switch region; other site
695560000339	Helix-turn-helix domain; Region: HTH_18; pfam12833
695560000340	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
695560000341	Transposase; Region: DEDD_Tnp_IS110; pfam01548
695560000342	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
695560000343	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
695560000344	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
695560000345	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
695560000346	Helix-turn-helix domain; Region: HTH_28; pfam13518
695560000347	putative transposase OrfB; Reviewed; Region: PHA02517
695560000348	HTH-like domain; Region: HTH_21; pfam13276
695560000349	Integrase core domain; Region: rve; pfam00665
695560000350	Integrase core domain; Region: rve_2; pfam13333
695560000351	heat shock protein HtpX; Provisional; Region: PRK04897
695560000352	Uncharacterized conserved protein [Function unknown]; Region: LemA; COG1704
695560000353	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
695560000354	transmembrane helices; other site
695560000355	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
695560000356	Membrane domain of glycerophosphoryl diester phosphodiesterase; Region: GPDPase_memb; pfam10110
695560000357	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
695560000358	Glycerophosphodiester phosphodiesterase domain of uncharacterized bacterial glycerophosphodiester phosphodiesterases; Region: GDPD_memb_like; cd08579
695560000359	putative active site [active]
695560000360	catalytic site [active]
695560000361	putative metal binding site [ion binding]; other site
695560000362	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
695560000363	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
695560000364	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
695560000365	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
695560000366	DXD motif; other site
695560000367	Glycosyl hydrolases family 8; Region: Glyco_hydro_8; cl01351
695560000368	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
695560000369	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
695560000370	putative substrate translocation pore; other site
695560000371	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
695560000372	Zn2+ binding site [ion binding]; other site
695560000373	Mg2+ binding site [ion binding]; other site
695560000374	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
695560000375	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
695560000376	active site
695560000377	Protein of unknown function (DUF805); Region: DUF805; pfam05656
695560000378	Protein of unknown function (DUF805); Region: DUF805; pfam05656
695560000379	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
695560000380	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
695560000381	Walker A/P-loop; other site
695560000382	ATP binding site [chemical binding]; other site
695560000383	Q-loop/lid; other site
695560000384	ABC transporter signature motif; other site
695560000385	Walker B; other site
695560000386	D-loop; other site
695560000387	H-loop/switch region; other site
695560000388	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
695560000389	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
695560000390	substrate binding pocket [chemical binding]; other site
695560000391	membrane-bound complex binding site; other site
695560000392	hinge residues; other site
695560000393	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
695560000394	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
695560000395	dimer interface [polypeptide binding]; other site
695560000396	conserved gate region; other site
695560000397	putative PBP binding loops; other site
695560000398	ABC-ATPase subunit interface; other site
695560000399	Alkyladenine DNA glycosylase catalyzes the first step in base excision repair; Region: AAG; cd00540
695560000400	active site
695560000401	DNA binding site [nucleotide binding]
695560000402	Uncharacterized conserved protein [Function unknown]; Region: COG3189
695560000403	integral membrane protein, YkoY family; Region: R_switched_YkoY; TIGR03716
695560000404	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
695560000405	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
695560000406	DNA binding site [nucleotide binding]
695560000407	active site
695560000408	NAD-dependent deacetylase; Provisional; Region: PRK00481
695560000409	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
695560000410	Zinc dependent phospholipase C/S1-P1 nuclease; Region: ZnPC_S1P1; cl16915
695560000411	cardiolipin synthase; Region: bac_cardiolipin; TIGR04265
695560000412	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
695560000413	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
695560000414	putative active site [active]
695560000415	catalytic site [active]
695560000416	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
695560000417	putative active site [active]
695560000418	catalytic site [active]
695560000419	Alpha/beta hydrolase of unknown function (DUF915); Region: DUF915; pfam06028
695560000420	Caulimovirus viroplasmin; Region: Cauli_VI; pfam01693
695560000421	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
695560000422	RNA/DNA hybrid binding site [nucleotide binding]; other site
695560000423	active site
695560000424	Predicted secreted protein [Function unknown]; Region: COG4086
695560000425	Protein of unknown function (DUF1002); Region: DUF1002; pfam06207
695560000426	putative glycosyl transferase; Provisional; Region: PRK10073
695560000427	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
695560000428	active site
695560000429	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
695560000430	alpha/beta hydrolase fold; Region: Abhydrolase_1; pfam00561
695560000431	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
695560000432	NADH(P)-binding; Region: NAD_binding_10; pfam13460
695560000433	NAD(P) binding site [chemical binding]; other site
695560000434	active site
695560000435	potential frameshift: common BLAST hit: gi|284047876|ref|YP_003398215.1| transcriptional regulator
695560000436	potential frameshift: common BLAST hit: gi|284047876|ref|YP_003398215.1| transcriptional regulator
695560000437	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
695560000438	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
695560000439	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
695560000440	active site
695560000441	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
695560000442	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
695560000443	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
695560000444	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
695560000445	substrate binding pocket [chemical binding]; other site
695560000446	membrane-bound complex binding site; other site
695560000447	hinge residues; other site
695560000448	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
695560000449	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
695560000450	dimer interface [polypeptide binding]; other site
695560000451	conserved gate region; other site
695560000452	putative PBP binding loops; other site
695560000453	ABC-ATPase subunit interface; other site
695560000454	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
695560000455	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
695560000456	Walker A/P-loop; other site
695560000457	ATP binding site [chemical binding]; other site
695560000458	Q-loop/lid; other site
695560000459	ABC transporter signature motif; other site
695560000460	Walker B; other site
695560000461	D-loop; other site
695560000462	H-loop/switch region; other site
695560000463	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
695560000464	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
695560000465	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
695560000466	ATP-grasp domain; Region: ATP-grasp_4; cl17255
695560000467	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
695560000468	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
695560000469	DNA binding residues [nucleotide binding]
695560000470	Bacterial protein of unknown function (DUF948); Region: DUF948; cl01972
695560000471	YibE/F-like protein; Region: YibE_F; pfam07907
695560000472	YibE/F-like protein; Region: YibE_F; pfam07907
695560000473	Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657
695560000474	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
695560000475	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
695560000476	The enzymes of glycosyl hydrolase family 31 (GH31) occur in prokaryotes, eukaryotes, and archaea with a wide range of hydrolytic activities, including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-xylosidase, 6-alpha-glucosyltransferase; Region: GH31; cl11402
695560000477	active site
695560000478	catalytic site [active]
695560000479	The enzymes of glycosyl hydrolase family 31 (GH31) occur in prokaryotes, eukaryotes, and archaea with a wide range of hydrolytic activities, including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-xylosidase, 6-alpha-glucosyltransferase; Region: GH31; cl11402
695560000480	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
695560000481	Interdomain contacts; other site
695560000482	Cytokine receptor motif; other site
695560000483	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
695560000484	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
695560000485	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
695560000486	active site
695560000487	dimer interface [polypeptide binding]; other site
695560000488	Nucleoside 2-deoxyribosyltransferase; Region: Nuc_deoxyrib_tr; pfam05014
695560000489	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
695560000490	active site
695560000491	phosphorylation site [posttranslational modification]
695560000492	Tyrosine phosphatase family; Region: Y_phosphatase3; pfam13350
695560000493	Tyrosine phosphatase family C-terminal region; Region: Y_phosphatase3C; pfam13348
695560000494	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
695560000495	Ligand Binding Site [chemical binding]; other site
695560000496	ABC-type phosphate/phosphonate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PhnD; COG3221
695560000497	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
695560000498	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
695560000499	membrane-bound complex binding site; other site
695560000500	hinge residues; other site
695560000501	ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: COG3638
695560000502	ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Region: ABC_PhnC_transporter; cd03256
695560000503	Walker A/P-loop; other site
695560000504	ATP binding site [chemical binding]; other site
695560000505	Q-loop/lid; other site
695560000506	ABC transporter signature motif; other site
695560000507	Walker B; other site
695560000508	D-loop; other site
695560000509	H-loop/switch region; other site
695560000510	phosphonate ABC transporter, permease protein PhnE; Region: PhnE; TIGR01097
695560000511	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
695560000512	dimer interface [polypeptide binding]; other site
695560000513	conserved gate region; other site
695560000514	putative PBP binding loops; other site
695560000515	ABC-ATPase subunit interface; other site
695560000516	phosphonate ABC transporter, permease protein PhnE; Region: PhnE; TIGR01097
695560000517	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
695560000518	dimer interface [polypeptide binding]; other site
695560000519	conserved gate region; other site
695560000520	putative PBP binding loops; other site
695560000521	ABC-ATPase subunit interface; other site
695560000522	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
695560000523	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
695560000524	active site
695560000525	metal binding site [ion binding]; metal-binding site
695560000526	exosortase A system-associated amidotransferase 1; Region: eps_aminotran_1; TIGR03108
695560000527	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
695560000528	active site
695560000529	dimer interface [polypeptide binding]; other site
695560000530	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
695560000531	Ligand Binding Site [chemical binding]; other site
695560000532	Molecular Tunnel; other site
695560000533	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
695560000534	Predicted ATP-grasp enzyme [General function prediction only]; Region: COG3919
695560000535	ATP-grasp domain; Region: ATP-grasp_4; cl17255
695560000536	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
695560000537	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
695560000538	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
695560000539	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
695560000540	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
695560000541	ATP cone domain; Region: ATP-cone; pfam03477
695560000542	Class III ribonucleotide reductase; Region: RNR_III; cd01675
695560000543	effector binding site; other site
695560000544	active site
695560000545	Zn binding site [ion binding]; other site
695560000546	glycine loop; other site
695560000547	anaerobic ribonucleotide reductase-activating protein; Provisional; Region: nrdG; cl15804
695560000548	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
695560000549	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
695560000550	Domain of unknown function (DUF1858); Region: DUF1858; pfam08984
695560000551	Uncharacterized conserved protein [Function unknown]; Region: COG2461
695560000552	Family of unknown function (DUF438); Region: DUF438; pfam04282
695560000553	Hemerythrin HHE cation binding domain; Region: Hemerythrin; pfam01814
695560000554	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
695560000555	Major Facilitator Superfamily; Region: MFS_1; pfam07690
695560000556	putative substrate translocation pore; other site
695560000557	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
695560000558	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
695560000559	active site
695560000560	Zn binding site [ion binding]; other site
695560000561	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
695560000562	Probable transposase; Region: OrfB_IS605; pfam01385
695560000563	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
695560000564	K+ potassium transporter; Region: K_trans; pfam02705
695560000565	RloB-like protein; Region: RloB; pfam13707
695560000566	Transposase IS200 like; Region: Y1_Tnp; pfam01797
695560000567	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
695560000568	Probable transposase; Region: OrfB_IS605; pfam01385
695560000569	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
695560000570	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
695560000571	AAA domain; Region: AAA_21; pfam13304
695560000572	Walker A/P-loop; other site
695560000573	ATP binding site [chemical binding]; other site
695560000574	Protein of unknown function (DUF2922); Region: DUF2922; pfam11148
695560000575	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
695560000576	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
695560000577	Bacterial surface layer protein; Region: SLAP; pfam03217
695560000578	Predicted membrane protein [Function unknown]; Region: COG4083; cl15694
695560000579	putative glycosyltransferase, exosortase G-associated; Region: glyc2_xrt_Gpos1; TIGR03111
695560000580	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
695560000581	DXD motif; other site
695560000582	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
695560000583	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
695560000584	AAA domain; Region: AAA_14; pfam13173
695560000585	Bacterial surface layer protein; Region: SLAP; pfam03217
695560000586	Protein of unknown function (DUF4065); Region: DUF4065; pfam13274
695560000587	Serine dehydratase alpha chain; Region: SDH_alpha; cl12120
695560000588	Bacterial surface layer protein; Region: SLAP; pfam03217
695560000589	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; cl17361
695560000590	Bacterial surface layer protein; Region: SLAP; pfam03217
695560000591	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
695560000592	amidase catalytic site [active]
695560000593	Zn binding residues [ion binding]; other site
695560000594	substrate binding site [chemical binding]; other site
695560000595	Bacterial surface layer protein; Region: SLAP; pfam03217
695560000596	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
695560000597	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
695560000598	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
695560000599	TrkA-N domain; Region: TrkA_N; pfam02254
695560000600	TrkA-C domain; Region: TrkA_C; pfam02080
695560000601	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
695560000602	AAA domain; Region: AAA_14; pfam13173
695560000603	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
695560000604	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
695560000605	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
695560000606	catalytic core [active]
695560000607	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
695560000608	Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I:  Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from...; Region: Peptidase_C15; cd00501
695560000609	putative substrate binding pocket [chemical binding]; other site
695560000610	AC domain interface; other site
695560000611	catalytic triad [active]
695560000612	AB domain interface; other site
695560000613	interchain disulfide; other site
695560000614	aldose 1-epimerase superfamily; Region: Aldose_epim; cl14648
695560000615	Cell envelope-related transcriptional attenuator domain; Region: LytR_cpsA_psr; cl00581
695560000616	membrane protein; Provisional; Region: PRK14411
695560000617	Sulfatase; Region: Sulfatase; cl17466
695560000618	tyrosyl-tRNA synthetase; Provisional; Region: PRK13354
695560000619	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
695560000620	active site
695560000621	HIGH motif; other site
695560000622	dimer interface [polypeptide binding]; other site
695560000623	KMSKS motif; other site
695560000624	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
695560000625	RNA binding surface [nucleotide binding]; other site
695560000626	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
695560000627	Probable transposase; Region: OrfB_IS605; pfam01385
695560000628	Helix-turn-helix domain; Region: HTH_38; pfam13936
695560000629	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
695560000630	DNA-binding interface [nucleotide binding]; DNA binding site
695560000631	Integrase core domain; Region: rve; pfam00665
695560000632	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
695560000633	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
695560000634	Sec23/Sec24 zinc finger; Region: zf-Sec23_Sec24; pfam04810
695560000635	Peptidase C1B subfamily (MEROPS database nomenclature); composed of eukaryotic bleomycin hydrolases (BH) and bacterial aminopeptidases C (pepC). The proteins of this subfamily contain a large insert relative to the C1A peptidase (papain) subfamily. BH is...; Region: Peptidase_C1B; cd00585
695560000636	trimer interface [polypeptide binding]; other site
695560000637	active site
695560000638	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
695560000639	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215
695560000640	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
695560000641	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
695560000642	peptide binding site [polypeptide binding]; other site
695560000643	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
695560000644	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
695560000645	peptide binding site [polypeptide binding]; other site
695560000646	inosine 5-monophosphate dehydrogenase; Validated; Region: PRK06843
695560000647	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
695560000648	active site
695560000649	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
695560000650	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
695560000651	dimer interface [polypeptide binding]; other site
695560000652	conserved gate region; other site
695560000653	putative PBP binding loops; other site
695560000654	ABC-ATPase subunit interface; other site
695560000655	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
695560000656	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
695560000657	dimer interface [polypeptide binding]; other site
695560000658	conserved gate region; other site
695560000659	putative PBP binding loops; other site
695560000660	ABC-ATPase subunit interface; other site
695560000661	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
695560000662	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
695560000663	Walker A/P-loop; other site
695560000664	ATP binding site [chemical binding]; other site
695560000665	Q-loop/lid; other site
695560000666	ABC transporter signature motif; other site
695560000667	Walker B; other site
695560000668	D-loop; other site
695560000669	H-loop/switch region; other site
695560000670	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
695560000671	ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; Region: AppF; COG4608
695560000672	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
695560000673	Walker A/P-loop; other site
695560000674	ATP binding site [chemical binding]; other site
695560000675	Q-loop/lid; other site
695560000676	ABC transporter signature motif; other site
695560000677	Walker B; other site
695560000678	D-loop; other site
695560000679	H-loop/switch region; other site
695560000680	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
695560000681	Peptidase C1B subfamily (MEROPS database nomenclature); composed of eukaryotic bleomycin hydrolases (BH) and bacterial aminopeptidases C (pepC). The proteins of this subfamily contain a large insert relative to the C1A peptidase (papain) subfamily. BH is...; Region: Peptidase_C1B; cd00585
695560000682	trimer interface [polypeptide binding]; other site
695560000683	active site
695560000684	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
695560000685	Group of bacterial proteins containing an alpha crystallin domain (ACD) similar to Lactobacillus plantarum (Lp) small heat shock proteins (sHsp) HSP 18.5, HSP 18.55 and HSP 19.3. sHsps are molecular chaperones that suppress protein aggregation and...; Region: ACD_LpsHSP_like; cd06471
695560000686	putative dimer interface [polypeptide binding]; other site
695560000687	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
695560000688	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
695560000689	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
695560000690	CAAX protease self-immunity; Region: Abi; pfam02517
695560000691	Uncharacterized ACR, COG2135; Region: DUF159; pfam02586
695560000692	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
695560000693	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
695560000694	active site
695560000695	HIGH motif; other site
695560000696	dimer interface [polypeptide binding]; other site
695560000697	KMSKS motif; other site
695560000698	Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286
695560000699	catalytic motif [active]
695560000700	Zn binding site [ion binding]; other site
695560000701	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
695560000702	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
695560000703	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
695560000704	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
695560000705	Soluble P-type ATPase [General function prediction only]; Region: COG4087
695560000706	methionyl-tRNA synthetase; Reviewed; Region: PRK12267
695560000707	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
695560000708	active site
695560000709	HIGH motif; other site
695560000710	KMSKS motif; other site
695560000711	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
695560000712	tRNA binding surface [nucleotide binding]; other site
695560000713	anticodon binding site; other site
695560000714	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
695560000715	dimer interface [polypeptide binding]; other site
695560000716	putative tRNA-binding site [nucleotide binding]; other site
695560000717	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
695560000718	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
695560000719	active site
695560000720	TOPRIM_ RNase M5_like: The topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain found in Ribonuclease M5: (RNase M5) and other small primase-like proteins from bacteria and archaea.  RNase M5 catalyzes the maturation of 5S rRNA in low...; Region: TOPRIM_RNase_M5_like; cd01027
695560000721	ribonuclease M5; Region: 5S_RNA_mat_M5; TIGR00334
695560000722	putative active site [active]
695560000723	putative metal binding site [ion binding]; other site
695560000724	Domain of unknown function (DUF4093); Region: DUF4093; pfam13331
695560000725	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
695560000726	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
695560000727	Protein of unknown function (DUF1021); Region: DUF1021; pfam06257
695560000728	pur operon repressor; Provisional; Region: PRK09213
695560000729	Bacterial purine repressor, N-terminal; Region: PuR_N; pfam09182
695560000730	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
695560000731	active site
695560000732	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14354
695560000733	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
695560000734	Substrate binding site; other site
695560000735	Mg++ binding site; other site
695560000736	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
695560000737	active site
695560000738	substrate binding site [chemical binding]; other site
695560000739	CoA binding site [chemical binding]; other site
695560000740	Bacterial surface layer protein; Region: SLAP; pfam03217
695560000741	Bacterial surface layer protein; Region: SLAP; pfam03217
695560000742	Bacterial surface layer protein; Region: SLAP; pfam03217
695560000743	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
695560000744	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
695560000745	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
695560000746	active site
695560000747	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
695560000748	potential frameshift: common BLAST hit: gi|58336568|ref|YP_193153.1| cellobiose-specific PTS IIC
695560000749	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
695560000750	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
695560000751	nucleotide binding site [chemical binding]; other site
695560000752	HD superfamily phosphohydrolases [General function prediction only]; Region: COG1078
695560000753	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
695560000754	Zn2+ binding site [ion binding]; other site
695560000755	Mg2+ binding site [ion binding]; other site
695560000756	Domain of unknown function (DUF1934); Region: DUF1934; pfam09148
695560000757	DNA-directed RNA polymerase delta subunit; Region: RNA_pol_delta; pfam05066
695560000758	CTP synthetase; Validated; Region: pyrG; PRK05380
695560000759	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
695560000760	Catalytic site [active]
695560000761	active site
695560000762	UTP binding site [chemical binding]; other site
695560000763	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
695560000764	active site
695560000765	putative oxyanion hole; other site
695560000766	catalytic triad [active]
695560000767	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
695560000768	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
695560000769	hinge; other site
695560000770	active site
695560000771	Peptidase family C69; Region: Peptidase_C69; pfam03577
695560000772	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
695560000773	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
695560000774	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
695560000775	Protein of unknown function (DUF1211); Region: DUF1211; cl01421
695560000776	xanthine permease; Region: pbuX; TIGR03173
695560000777	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
695560000778	active site
695560000779	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
695560000780	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
695560000781	non-specific DNA binding site [nucleotide binding]; other site
695560000782	salt bridge; other site
695560000783	sequence-specific DNA binding site [nucleotide binding]; other site
695560000784	GMP synthase; Reviewed; Region: guaA; PRK00074
695560000785	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
695560000786	AMP/PPi binding site [chemical binding]; other site
695560000787	candidate oxyanion hole; other site
695560000788	catalytic triad [active]
695560000789	potential glutamine specificity residues [chemical binding]; other site
695560000790	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
695560000791	ATP Binding subdomain [chemical binding]; other site
695560000792	Ligand Binding sites [chemical binding]; other site
695560000793	Dimerization subdomain; other site
695560000794	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
695560000795	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
695560000796	DNA binding site [nucleotide binding]
695560000797	active site
695560000798	polyphosphate:nucleotide phosphotransferase, PPK2 family; Region: PPK2_rel_1; TIGR03709
695560000799	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
695560000800	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
695560000801	Coenzyme A binding pocket [chemical binding]; other site
695560000802	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
695560000803	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
695560000804	dimer interface [polypeptide binding]; other site
695560000805	active site
695560000806	glycine-pyridoxal phosphate binding site [chemical binding]; other site
695560000807	folate binding site [chemical binding]; other site
695560000808	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
695560000809	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
695560000810	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
695560000811	potential frameshift: common BLAST hit: gi|295692129|ref|YP_003600739.1| alpha,alpha-phosphotrehalase
695560000812	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
695560000813	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
695560000814	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
695560000815	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
695560000816	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
695560000817	DEAD-like helicases superfamily; Region: DEXDc; smart00487
695560000818	ATP binding site [chemical binding]; other site
695560000819	Mg++ binding site [ion binding]; other site
695560000820	motif III; other site
695560000821	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
695560000822	nucleotide binding region [chemical binding]; other site
695560000823	ATP-binding site [chemical binding]; other site
695560000824	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
695560000825	alanine racemase; Reviewed; Region: alr; PRK00053
695560000826	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
695560000827	active site
695560000828	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
695560000829	dimer interface [polypeptide binding]; other site
695560000830	substrate binding site [chemical binding]; other site
695560000831	catalytic residues [active]
695560000832	FOG: CBS domain [General function prediction only]; Region: COG0517
695560000833	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
695560000834	L-lactate dehydrogenase; Reviewed; Region: ldh; PRK00066
695560000835	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
695560000836	tetramer (dimer of dimers) interface [polypeptide binding]; other site
695560000837	NAD binding site [chemical binding]; other site
695560000838	dimer interface [polypeptide binding]; other site
695560000839	substrate binding site [chemical binding]; other site
695560000840	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
695560000841	putative active site [active]
695560000842	catalytic residue [active]
695560000843	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
695560000844	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
695560000845	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
695560000846	ATP binding site [chemical binding]; other site
695560000847	putative Mg++ binding site [ion binding]; other site
695560000848	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
695560000849	nucleotide binding region [chemical binding]; other site
695560000850	ATP-binding site [chemical binding]; other site
695560000851	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
695560000852	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
695560000853	RNA binding surface [nucleotide binding]; other site
695560000854	Septum formation initiator; Region: DivIC; pfam04977
695560000855	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
695560000856	RNA binding site [nucleotide binding]; other site
695560000857	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
695560000858	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
695560000859	Ligand Binding Site [chemical binding]; other site
695560000860	FtsH Extracellular; Region: FtsH_ext; pfam06480
695560000861	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
695560000862	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
695560000863	Walker A motif; other site
695560000864	ATP binding site [chemical binding]; other site
695560000865	Walker B motif; other site
695560000866	arginine finger; other site
695560000867	Peptidase family M41; Region: Peptidase_M41; pfam01434
695560000868	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
695560000869	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
695560000870	dimerization interface [polypeptide binding]; other site
695560000871	domain crossover interface; other site
695560000872	redox-dependent activation switch; other site
695560000873	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
695560000874	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
695560000875	FMN binding site [chemical binding]; other site
695560000876	active site
695560000877	catalytic residues [active]
695560000878	substrate binding site [chemical binding]; other site
695560000879	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
695560000880	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
695560000881	dimer interface [polypeptide binding]; other site
695560000882	putative anticodon binding site; other site
695560000883	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
695560000884	motif 1; other site
695560000885	active site
695560000886	motif 2; other site
695560000887	motif 3; other site
695560000888	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
695560000889	Coenzyme A binding pocket [chemical binding]; other site
695560000890	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
695560000891	GAF domain; Region: GAF_2; pfam13185
695560000892	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
695560000893	Clp amino terminal domain; Region: Clp_N; pfam02861
695560000894	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
695560000895	Walker A motif; other site
695560000896	ATP binding site [chemical binding]; other site
695560000897	Walker B motif; other site
695560000898	arginine finger; other site
695560000899	UvrB/uvrC motif; Region: UVR; pfam02151
695560000900	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
695560000901	Walker A motif; other site
695560000902	ATP binding site [chemical binding]; other site
695560000903	Walker B motif; other site
695560000904	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
695560000905	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
695560000906	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
695560000907	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
695560000908	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
695560000909	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
695560000910	RPB1 interaction site [polypeptide binding]; other site
695560000911	RPB10 interaction site [polypeptide binding]; other site
695560000912	RPB11 interaction site [polypeptide binding]; other site
695560000913	RPB3 interaction site [polypeptide binding]; other site
695560000914	RPB12 interaction site [polypeptide binding]; other site
695560000915	DNA-directed RNA polymerase subunit beta'; Provisional; Region: PRK00566
695560000916	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
695560000917	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
695560000918	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
695560000919	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
695560000920	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
695560000921	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
695560000922	G-loop; other site
695560000923	DNA binding site [nucleotide binding]
695560000924	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
695560000925	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
695560000926	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
695560000927	S17 interaction site [polypeptide binding]; other site
695560000928	S8 interaction site; other site
695560000929	16S rRNA interaction site [nucleotide binding]; other site
695560000930	streptomycin interaction site [chemical binding]; other site
695560000931	23S rRNA interaction site [nucleotide binding]; other site
695560000932	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
695560000933	30S ribosomal protein S7; Validated; Region: PRK05302
695560000934	elongation factor G; Reviewed; Region: PRK12739
695560000935	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
695560000936	G1 box; other site
695560000937	putative GEF interaction site [polypeptide binding]; other site
695560000938	GTP/Mg2+ binding site [chemical binding]; other site
695560000939	Switch I region; other site
695560000940	G2 box; other site
695560000941	G3 box; other site
695560000942	Switch II region; other site
695560000943	G4 box; other site
695560000944	G5 box; other site
695560000945	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
695560000946	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
695560000947	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
695560000948	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
695560000949	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
695560000950	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
695560000951	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
695560000952	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
695560000953	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
695560000954	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
695560000955	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
695560000956	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
695560000957	putative translocon binding site; other site
695560000958	protein-rRNA interface [nucleotide binding]; other site
695560000959	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
695560000960	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
695560000961	G-X-X-G motif; other site
695560000962	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
695560000963	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
695560000964	23S rRNA interface [nucleotide binding]; other site
695560000965	5S rRNA interface [nucleotide binding]; other site
695560000966	putative antibiotic binding site [chemical binding]; other site
695560000967	L25 interface [polypeptide binding]; other site
695560000968	L27 interface [polypeptide binding]; other site
695560000969	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
695560000970	23S rRNA interface [nucleotide binding]; other site
695560000971	putative translocon interaction site; other site
695560000972	signal recognition particle (SRP54) interaction site; other site
695560000973	L23 interface [polypeptide binding]; other site
695560000974	trigger factor interaction site; other site
695560000975	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
695560000976	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
695560000977	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
695560000978	RNA binding site [nucleotide binding]; other site
695560000979	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
695560000980	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
695560000981	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
695560000982	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08061
695560000983	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
695560000984	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
695560000985	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
695560000986	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
695560000987	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
695560000988	5S rRNA interface [nucleotide binding]; other site
695560000989	23S rRNA interface [nucleotide binding]; other site
695560000990	L5 interface [polypeptide binding]; other site
695560000991	ribosomal protein S5, bacterial/organelle type; Region: rpsE_bact; TIGR01021
695560000992	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
695560000993	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
695560000994	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
695560000995	23S rRNA binding site [nucleotide binding]; other site
695560000996	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
695560000997	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
695560000998	SecY translocase; Region: SecY; pfam00344
695560000999	adenylate kinase; Reviewed; Region: adk; PRK00279
695560001000	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
695560001001	AMP-binding site [chemical binding]; other site
695560001002	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
695560001003	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
695560001004	rRNA binding site [nucleotide binding]; other site
695560001005	predicted 30S ribosome binding site; other site
695560001006	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
695560001007	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
695560001008	30S ribosomal protein S13; Region: bact_S13; TIGR03631
695560001009	30S ribosomal protein S11; Validated; Region: PRK05309
695560001010	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
695560001011	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
695560001012	alphaNTD homodimer interface [polypeptide binding]; other site
695560001013	alphaNTD - beta interaction site [polypeptide binding]; other site
695560001014	alphaNTD - beta' interaction site [polypeptide binding]; other site
695560001015	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
695560001016	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
695560001017	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13640
695560001018	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
695560001019	Walker A/P-loop; other site
695560001020	ATP binding site [chemical binding]; other site
695560001021	Q-loop/lid; other site
695560001022	ABC transporter signature motif; other site
695560001023	Walker B; other site
695560001024	D-loop; other site
695560001025	H-loop/switch region; other site
695560001026	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13641
695560001027	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
695560001028	Walker A/P-loop; other site
695560001029	ATP binding site [chemical binding]; other site
695560001030	Q-loop/lid; other site
695560001031	ABC transporter signature motif; other site
695560001032	Walker B; other site
695560001033	D-loop; other site
695560001034	H-loop/switch region; other site
695560001035	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
695560001036	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
695560001037	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
695560001038	dimerization interface 3.5A [polypeptide binding]; other site
695560001039	active site
695560001040	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
695560001041	23S rRNA interface [nucleotide binding]; other site
695560001042	L3 interface [polypeptide binding]; other site
695560001043	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
695560001044	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4619
695560001045	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
695560001046	Walker A/P-loop; other site
695560001047	ATP binding site [chemical binding]; other site
695560001048	Q-loop/lid; other site
695560001049	ABC transporter signature motif; other site
695560001050	Walker B; other site
695560001051	D-loop; other site
695560001052	H-loop/switch region; other site
695560001053	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG0390
695560001054	DJ-1 family protein; Region: not_thiJ; TIGR01383
695560001055	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
695560001056	conserved cys residue [active]
695560001057	haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E; Region: HAD-SF-IA-v1; TIGR01549
695560001058	REG-2-like, HAD superfamily (subfamily IA) hydrolase; Region: DREG-2; TIGR02252
695560001059	hypothetical protein; Provisional; Region: PRK10621
695560001060	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
695560001061	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
695560001062	catalytic core [active]
695560001063	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cl11399
695560001064	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
695560001065	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
695560001066	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
695560001067	catalytic core [active]
695560001068	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
695560001069	AAA domain; Region: AAA_33; pfam13671
695560001070	Peptidase C1B subfamily (MEROPS database nomenclature); composed of eukaryotic bleomycin hydrolases (BH) and bacterial aminopeptidases C (pepC). The proteins of this subfamily contain a large insert relative to the C1A peptidase (papain) subfamily. BH is...; Region: Peptidase_C1B; cd00585
695560001071	trimer interface [polypeptide binding]; other site
695560001072	active site
695560001073	G bulge; other site
695560001074	Predicted acetyltransferase [General function prediction only]; Region: COG2388
695560001075	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
695560001076	trimer interface [polypeptide binding]; other site
695560001077	active site
695560001078	DNA repair protein RadA; Provisional; Region: PRK11823
695560001079	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
695560001080	Walker A motif/ATP binding site; other site
695560001081	ATP binding site [chemical binding]; other site
695560001082	Walker B motif; other site
695560001083	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
695560001084	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
695560001085	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
695560001086	active site
695560001087	HIGH motif; other site
695560001088	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
695560001089	active site
695560001090	KMSKS motif; other site
695560001091	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
695560001092	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
695560001093	active site
695560001094	HIGH motif; other site
695560001095	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
695560001096	KMSKS motif; other site
695560001097	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
695560001098	tRNA binding surface [nucleotide binding]; other site
695560001099	anticodon binding site; other site
695560001100	Ribonuclease III family protein [Replication, recombination, and    repair]; Region: COG1939
695560001101	active site
695560001102	metal binding site [ion binding]; metal-binding site
695560001103	dimerization interface [polypeptide binding]; other site
695560001104	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
695560001105	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
695560001106	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
695560001107	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
695560001108	gluconate kinase, FGGY type; Region: gntK_FGGY; TIGR01314
695560001109	Gluconate kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_GntK; cd07770
695560001110	N- and C-terminal domain interface [polypeptide binding]; other site
695560001111	active site
695560001112	catalytic site [active]
695560001113	metal binding site [ion binding]; metal-binding site
695560001114	carbohydrate binding site [chemical binding]; other site
695560001115	ATP binding site [chemical binding]; other site
695560001116	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK12315
695560001117	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
695560001118	TPP-binding site; other site
695560001119	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
695560001120	PYR/PP interface [polypeptide binding]; other site
695560001121	dimer interface [polypeptide binding]; other site
695560001122	TPP binding site [chemical binding]; other site
695560001123	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
695560001124	50S ribosomal protein L33; Validated; Region: rpmG; PRK00504
695560001125	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK07597
695560001126	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
695560001127	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
695560001128	putative homodimer interface [polypeptide binding]; other site
695560001129	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
695560001130	heterodimer interface [polypeptide binding]; other site
695560001131	homodimer interface [polypeptide binding]; other site
695560001132	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
695560001133	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
695560001134	23S rRNA interface [nucleotide binding]; other site
695560001135	L7/L12 interface [polypeptide binding]; other site
695560001136	putative thiostrepton binding site; other site
695560001137	L25 interface [polypeptide binding]; other site
695560001138	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
695560001139	mRNA/rRNA interface [nucleotide binding]; other site
695560001140	potential frameshift: common BLAST hit: gi|58337731|ref|YP_194316.1| transposase
695560001141	PBP superfamily domain; Region: PBP_like_2; cl17296
695560001142	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
695560001143	phosphate ABC transporter, permease protein PstC; Region: phosphate_pstC; TIGR02138
695560001144	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
695560001145	dimer interface [polypeptide binding]; other site
695560001146	conserved gate region; other site
695560001147	putative PBP binding loops; other site
695560001148	ABC-ATPase subunit interface; other site
695560001149	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstA; COG0581
695560001150	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
695560001151	dimer interface [polypeptide binding]; other site
695560001152	conserved gate region; other site
695560001153	putative PBP binding loops; other site
695560001154	ABC-ATPase subunit interface; other site
695560001155	phosphate transporter ATP-binding protein; Provisional; Region: PRK14237
695560001156	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
695560001157	Walker A/P-loop; other site
695560001158	ATP binding site [chemical binding]; other site
695560001159	Q-loop/lid; other site
695560001160	ABC transporter signature motif; other site
695560001161	Walker B; other site
695560001162	D-loop; other site
695560001163	H-loop/switch region; other site
695560001164	phosphate ABC transporter ATP-binding protein; Provisional; Region: PRK14251
695560001165	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
695560001166	Walker A/P-loop; other site
695560001167	ATP binding site [chemical binding]; other site
695560001168	Q-loop/lid; other site
695560001169	ABC transporter signature motif; other site
695560001170	Walker B; other site
695560001171	D-loop; other site
695560001172	H-loop/switch region; other site
695560001173	phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135
695560001174	PhoU domain; Region: PhoU; pfam01895
695560001175	PhoU domain; Region: PhoU; pfam01895
695560001176	Membrane transport protein; Region: Mem_trans; cl09117
695560001177	Membrane transport protein; Region: Mem_trans; cl09117
695560001178	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
695560001179	23S rRNA interface [nucleotide binding]; other site
695560001180	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
695560001181	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
695560001182	core dimer interface [polypeptide binding]; other site
695560001183	peripheral dimer interface [polypeptide binding]; other site
695560001184	L10 interface [polypeptide binding]; other site
695560001185	L11 interface [polypeptide binding]; other site
695560001186	putative EF-Tu interaction site [polypeptide binding]; other site
695560001187	putative EF-G interaction site [polypeptide binding]; other site
695560001188	Ion channel; Region: Ion_trans_2; pfam07885
695560001189	Protein of unknown function (DUF904); Region: DUF904; pfam06005
695560001190	16S RNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; Region: RsmC; COG2813
695560001191	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
695560001192	S-adenosylmethionine binding site [chemical binding]; other site
695560001193	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
695560001194	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
695560001195	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
695560001196	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
695560001197	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
695560001198	nucleoside/Zn binding site; other site
695560001199	dimer interface [polypeptide binding]; other site
695560001200	catalytic motif [active]
695560001201	DNA polymerase III subunits gamma and tau; Validated; Region: PRK05563
695560001202	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
695560001203	Walker A motif; other site
695560001204	ATP binding site [chemical binding]; other site
695560001205	Walker B motif; other site
695560001206	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
695560001207	hypothetical protein; Validated; Region: PRK00153
695560001208	recombination protein RecR; Reviewed; Region: recR; PRK00076
695560001209	RecR protein; Region: RecR; pfam02132
695560001210	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
695560001211	putative active site [active]
695560001212	putative metal-binding site [ion binding]; other site
695560001213	tetramer interface [polypeptide binding]; other site
695560001214	Protein of unknown function (DUF2508); Region: DUF2508; pfam10704
695560001215	thymidylate kinase; Validated; Region: tmk; PRK00698
695560001216	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
695560001217	TMP-binding site; other site
695560001218	ATP-binding site [chemical binding]; other site
695560001219	Protein of unknown function (DUF970); Region: DUF970; cl17525
695560001220	DNA polymerase III, delta subunit; Region: DNA_pol3_delta2; pfam13177
695560001221	DNA polymerase III subunit delta'; Validated; Region: PRK08485
695560001222	DNA replication intiation control protein YabA; Reviewed; Region: PRK13169
695560001223	Predicted methyltransferases [General function prediction only]; Region: COG0313
695560001224	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
695560001225	putative SAM binding site [chemical binding]; other site
695560001226	putative homodimer interface [polypeptide binding]; other site
695560001227	Acyl-ACP thioesterase; Region: Acyl-ACP_TE; pfam01643
695560001228	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
695560001229	active site
695560001230	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
695560001231	active site 2 [active]
695560001232	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
695560001233	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
695560001234	Glycoprotease family; Region: Peptidase_M22; pfam00814
695560001235	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
695560001236	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
695560001237	Coenzyme A binding pocket [chemical binding]; other site
695560001238	UGMP family protein; Validated; Region: PRK09604
695560001239	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
695560001240	Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804
695560001241	CoA-transferase family III; Region: CoA_transf_3; pfam02515
695560001242	formyl-coenzyme A transferase; Provisional; Region: PRK05398
695560001243	CoA-transferase family III; Region: CoA_transf_3; pfam02515
695560001244	putative oxalyl-CoA decarboxylase; Validated; Region: PRK09259
695560001245	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
695560001246	PYR/PP interface [polypeptide binding]; other site
695560001247	dimer interface [polypeptide binding]; other site
695560001248	TPP binding site [chemical binding]; other site
695560001249	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
695560001250	Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of proteins similar to benzaldehyde lyase (BZL), oxalyl-CoA decarboxylase (OCoD) and 2-hydroxyphytanoyl-CoA lyase (2-HPCL). Pseudomonas fluorescens biovar I BZL...; Region: TPP_BZL_OCoD_HPCL; cd02004
695560001251	TPP-binding site; other site
695560001252	dimer interface [polypeptide binding]; other site
695560001253	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
695560001254	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
695560001255	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
695560001256	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
695560001257	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
695560001258	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
695560001259	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
695560001260	ABC transporter; Region: ABC_tran_2; pfam12848
695560001261	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
695560001262	redox-sensing transcriptional repressor Rex; Provisional; Region: PRK05472
695560001263	Putative DNA-binding protein N-terminus; Region: Put_DNA-bind_N; pfam06971
695560001264	CoA binding domain; Region: CoA_binding; pfam02629
695560001265	Transcriptional regulators [Transcription]; Region: PurR; COG1609
695560001266	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
695560001267	DNA binding site [nucleotide binding]
695560001268	domain linker motif; other site
695560001269	Ligand binding domain of the lacI-like transcription regulator from a novel metal-reducing bacterium Alkaliphilus Metalliredigens (strain Qymf) and its close homologs; Region: PBP1_Qymf_like; cd06291
695560001270	dimerization interface [polypeptide binding]; other site
695560001271	ligand binding site [chemical binding]; other site
695560001272	sodium binding site [ion binding]; other site
695560001273	sucrose-6-phosphate hydrolase; Region: scrB_fam; TIGR01322
695560001274	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
695560001275	substrate binding [chemical binding]; other site
695560001276	active site
695560001277	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
695560001278	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
695560001279	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
695560001280	active site turn [active]
695560001281	phosphorylation site [posttranslational modification]
695560001282	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
695560001283	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
695560001284	HPr interaction site; other site
695560001285	glycerol kinase (GK) interaction site [polypeptide binding]; other site
695560001286	active site
695560001287	phosphorylation site [posttranslational modification]
695560001288	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
695560001289	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
695560001290	non-specific DNA binding site [nucleotide binding]; other site
695560001291	salt bridge; other site
695560001292	sequence-specific DNA binding site [nucleotide binding]; other site
695560001293	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
695560001294	LytTr DNA-binding domain; Region: LytTR; smart00850
695560001295	The Tellurite-resistance/Dicarboxylate Transporter (TDT) family; Region: TDT; cl04176
695560001296	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
695560001297	oligomerisation interface [polypeptide binding]; other site
695560001298	mobile loop; other site
695560001299	roof hairpin; other site
695560001300	chaperonin GroL; Region: GroEL; TIGR02348
695560001301	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
695560001302	ring oligomerisation interface [polypeptide binding]; other site
695560001303	ATP/Mg binding site [chemical binding]; other site
695560001304	stacking interactions; other site
695560001305	hinge regions; other site
695560001306	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
695560001307	MutS domain I; Region: MutS_I; pfam01624
695560001308	MutS domain II; Region: MutS_II; pfam05188
695560001309	MutS domain III; Region: MutS_III; pfam05192
695560001310	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
695560001311	Walker A/P-loop; other site
695560001312	ATP binding site [chemical binding]; other site
695560001313	Q-loop/lid; other site
695560001314	ABC transporter signature motif; other site
695560001315	Walker B; other site
695560001316	D-loop; other site
695560001317	H-loop/switch region; other site
695560001318	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
695560001319	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
695560001320	ATP binding site [chemical binding]; other site
695560001321	Mg2+ binding site [ion binding]; other site
695560001322	G-X-G motif; other site
695560001323	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
695560001324	ATP binding site [chemical binding]; other site
695560001325	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
695560001326	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
695560001327	RuvA N terminal domain; Region: RuvA_N; pfam01330
695560001328	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
695560001329	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
695560001330	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
695560001331	Walker A motif; other site
695560001332	ATP binding site [chemical binding]; other site
695560001333	Walker B motif; other site
695560001334	arginine finger; other site
695560001335	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
695560001336	Preprotein translocase subunit; Region: YajC; pfam02699
695560001337	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
695560001338	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
695560001339	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
695560001340	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
695560001341	active site
695560001342	DNA polymerase IV; Validated; Region: PRK02406
695560001343	DNA binding site [nucleotide binding]
695560001344	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
695560001345	DHH family; Region: DHH; pfam01368
695560001346	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
695560001347	DEAD-like helicases superfamily; Region: DEXDc; smart00487
695560001348	ATP binding site [chemical binding]; other site
695560001349	putative Mg++ binding site [ion binding]; other site
695560001350	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
695560001351	nucleotide binding region [chemical binding]; other site
695560001352	ATP-binding site [chemical binding]; other site
695560001353	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
695560001354	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
695560001355	motif 1; other site
695560001356	active site
695560001357	motif 2; other site
695560001358	motif 3; other site
695560001359	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
695560001360	DHHA1 domain; Region: DHHA1; pfam02272
695560001361	hypothetical protein; Provisional; Region: PRK05473
695560001362	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
695560001363	hypothetical protein; Provisional; Region: PRK13678
695560001364	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
695560001365	MutS domain III; Region: MutS_III; pfam05192
695560001366	ATP-binding cassette domain of MutS2; Region: ABC_MutS2; cd03280
695560001367	Walker A/P-loop; other site
695560001368	ATP binding site [chemical binding]; other site
695560001369	Q-loop/lid; other site
695560001370	ABC transporter signature motif; other site
695560001371	Walker B; other site
695560001372	D-loop; other site
695560001373	H-loop/switch region; other site
695560001374	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
695560001375	Smr domain; Region: Smr; pfam01713
695560001376	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
695560001377	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
695560001378	catalytic residues [active]
695560001379	Transposase; Region: DEDD_Tnp_IS110; pfam01548
695560001380	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
695560001381	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
695560001382	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
695560001383	Gram-positive signal peptide, YSIRK family; Region: YSIRK_signal; TIGR01168
695560001384	MucBP domain; Region: MucBP; pfam06458
695560001385	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
695560001386	Transposase; Region: DEDD_Tnp_IS110; pfam01548
695560001387	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
695560001388	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
695560001389	potential frameshift: common BLAST hit: gi|313123705|ref|YP_004033964.1| transposase
695560001390	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
695560001391	Transposase; Region: DDE_Tnp_ISL3; pfam01610
695560001392	Helix-turn-helix domain of transposase family ISL3; Region: HTH_Tnp_ISL3; pfam13542
695560001393	Transposase; Region: DDE_Tnp_ISL3; pfam01610
695560001394	potential frameshift: common BLAST hit: gi|58337981|ref|YP_194566.1| transposase
695560001395	potential frameshift: common BLAST hit: gi|295693608|ref|YP_003602218.1| transposase
695560001396	large-conductance mechanosensitive channel; Provisional; Region: mscL; PRK13952
695560001397	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
695560001398	Protein of unknown function (DUF2507); Region: DUF2507; pfam10702
695560001399	glutamate racemase; Provisional; Region: PRK00865
695560001400	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
695560001401	active site
695560001402	dimerization interface [polypeptide binding]; other site
695560001403	Helix-turn-helix domain; Region: HTH_19; pfam12844
695560001404	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
695560001405	Mechanosensitive ion channel; Region: MS_channel; pfam00924
695560001406	Bacterial protein of unknown function (DUF948); Region: DUF948; pfam06103
695560001407	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
695560001408	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
695560001409	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
695560001410	active site
695560001411	catabolite control protein A; Region: ccpA; TIGR01481
695560001412	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
695560001413	DNA binding site [nucleotide binding]
695560001414	domain linker motif; other site
695560001415	Ligand-binding domain of the catabolite control protein A (CcpA), which functions as the major transcriptional regulator of carbon catabolite repression/regulation; Region: PBP1_CcpA_like; cd06298
695560001416	dimerization interface [polypeptide binding]; other site
695560001417	effector binding site; other site
695560001418	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
695560001419	Glycerophosphodiester phosphodiesterase domain as found in prokaryota and eukaryota, and similar proteins; Region: GDPD; cd08556
695560001420	active site
695560001421	catalytic site [active]
695560001422	metal binding site [ion binding]; metal-binding site
695560001423	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
695560001424	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
695560001425	active site
695560001426	metal binding site [ion binding]; metal-binding site
695560001427	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
695560001428	Protein of unknown function (DUF1027); Region: DUF1027; cl09961
695560001429	HAD-superfamily subfamily IIA hydrolase, TIGR01457; Region: HAD-SF-IIA-hyp2
695560001430	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
695560001431	active site
695560001432	motif I; other site
695560001433	motif II; other site
695560001434	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
695560001435	Protein of unknown function (DUF1461); Region: DUF1461; pfam07314
695560001436	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
695560001437	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
695560001438	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
695560001439	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
695560001440	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
695560001441	active site
695560001442	8-oxo-dGMP binding site [chemical binding]; other site
695560001443	nudix motif; other site
695560001444	metal binding site [ion binding]; metal-binding site
695560001445	potential protein location (hypothetical protein LA2_02350 [Lactobacillus amylovorus GRL 1112]) that overlaps RNA (tRNA-H)
695560001446	This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1; Region: GT1_UGDG_like; cd03817
695560001447	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
695560001448	putative ADP-binding pocket [chemical binding]; other site
695560001449	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
695560001450	Glycosyl transferase 4-like domain; Region: Glyco_trans_4_4; pfam13579
695560001451	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
695560001452	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
695560001453	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
695560001454	Polysaccharide biosynthesis protein; Region: Polysacc_synt_3; pfam13440
695560001455	Sulfatase; Region: Sulfatase; pfam00884
695560001456	preprotein translocase subunit SecG; Reviewed; Region: secG; PRK06870
695560001457	ribonuclease R; Region: RNase_R; TIGR02063
695560001458	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
695560001459	RNB domain; Region: RNB; pfam00773
695560001460	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
695560001461	RNA binding site [nucleotide binding]; other site
695560001462	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
695560001463	SmpB-tmRNA interface; other site
695560001464	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
695560001465	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
695560001466	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
695560001467	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
695560001468	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
695560001469	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
695560001470	active pocket/dimerization site; other site
695560001471	active site
695560001472	phosphorylation site [posttranslational modification]
695560001473	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
695560001474	active site
695560001475	phosphorylation site [posttranslational modification]
695560001476	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
695560001477	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
695560001478	Domain of unknown function (DUF956); Region: DUF956; pfam06115
695560001479	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
695560001480	Helix-turn-helix domain; Region: HTH_28; pfam13518
695560001481	putative transposase OrfB; Reviewed; Region: PHA02517
695560001482	HTH-like domain; Region: HTH_21; pfam13276
695560001483	Integrase core domain; Region: rve; pfam00665
695560001484	Integrase core domain; Region: rve_2; pfam13333
695560001485	Transcriptional regulator [Transcription]; Region: LysR; COG0583
695560001486	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
695560001487	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
695560001488	dimerization interface [polypeptide binding]; other site
695560001489	potential frameshift: common BLAST hit: gi|295692324|ref|YP_003600934.1| Maltose o-acetyltransferase
695560001490	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
695560001491	Spore germination protein; Region: Spore_permease; cl17796
695560001492	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
695560001493	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
695560001494	putative catalytic cysteine [active]
695560001495	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
695560001496	putative active site [active]
695560001497	metal binding site [ion binding]; metal-binding site
695560001498	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
695560001499	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
695560001500	glutaminase active site [active]
695560001501	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
695560001502	dimer interface [polypeptide binding]; other site
695560001503	active site
695560001504	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
695560001505	dimer interface [polypeptide binding]; other site
695560001506	active site
695560001507	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
695560001508	HTH domain; Region: HTH_11; pfam08279
695560001509	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
695560001510	active site
695560001511	P-loop; other site
695560001512	phosphorylation site [posttranslational modification]
695560001513	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cl00163
695560001514	Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism]; Region: MtlA; COG2213
695560001515	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
695560001516	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
695560001517	active site
695560001518	P-loop; other site
695560001519	phosphorylation site [posttranslational modification]
695560001520	PTS_IIB: subunit IIB of enzyme II (EII) is the central energy-coupling domain of the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In the multienzyme PTS complex, EII is a carbohydrate-specific permease consisting of two cytoplasmic...; Region: PTS_IIB; cl10014
695560001521	active site
695560001522	P-loop; other site
695560001523	phosphorylation site [posttranslational modification]
695560001524	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
695560001525	active site
695560001526	phosphorylation site [posttranslational modification]
695560001527	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
695560001528	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
695560001529	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
695560001530	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
695560001531	propionate/acetate kinase; Provisional; Region: PRK12379
695560001532	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
695560001533	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
695560001534	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Ap4A hydrolases are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_human_like; cd03428
695560001535	active site
695560001536	Ap4A binding cleft/pocket [chemical binding]; other site
695560001537	P4 phosphate binding site; other site
695560001538	nudix motif; other site
695560001539	putative P2/P3 phosphate binding site [ion binding]; other site
695560001540	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_HprK; cl00270
695560001541	active site
695560001542	metal-binding site [ion binding]
695560001543	nucleotide-binding site [chemical binding]; other site
695560001544	P-loop Domain of unknown function (DUF2791); Region: DUF2791; pfam10923
695560001545	AAA ATPase domain; Region: AAA_16; pfam13191
695560001546	DEAD-like helicases superfamily; Region: DEXDc; smart00487
695560001547	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
695560001548	ATP binding site [chemical binding]; other site
695560001549	putative Mg++ binding site [ion binding]; other site
695560001550	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
695560001551	nucleotide binding region [chemical binding]; other site
695560001552	ATP-binding site [chemical binding]; other site
695560001553	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK14481
695560001554	Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Region: DAK1; COG2376
695560001555	dihydroxyacetone kinase, phosphoprotein-dependent, L subunit; Region: dha_L_ycgS; TIGR02365
695560001556	phosphotransferase mannnose-specific family component IIA; Provisional; Region: PRK14484
695560001557	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
695560001558	amphipathic channel; other site
695560001559	Asn-Pro-Ala signature motifs; other site
695560001560	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
695560001561	dimer interface [polypeptide binding]; other site
695560001562	FMN binding site [chemical binding]; other site
695560001563	NADPH bind site [chemical binding]; other site
695560001564	putative monovalent cation/H+ antiporter subunit A; Reviewed; Region: PRK12648
695560001565	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
695560001566	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
695560001567	potential frameshift: common BLAST hit: gi|161507888|ref|YP_001577852.1| transposase
695560001568	Family 41 Carbohydrate-Binding Module from pullulanase-like enzymes; Region: CBM41_pullulanase; cd10315
695560001569	carbohydrate binding site [chemical binding]; other site
695560001570	pullulanase, type I; Region: pulA_typeI; TIGR02104
695560001571	Early set domain associated with the catalytic domain of pullulanase (also called dextrinase and alpha-dextrin endo-1,6-alpha glucosidase); Region: E_set_Pullulanase; cd02860
695560001572	Alpha amylase catalytic domain found in Pullulanase (also called dextrinase; alpha-dextrin endo-1,6-alpha glucosidase), limit dextrinase, and related proteins; Region: AmyAc_Pullulanase_LD-like; cd11341
695560001573	Ca binding site [ion binding]; other site
695560001574	active site
695560001575	catalytic site [active]
695560001576	Bacterial surface layer protein; Region: SLAP; pfam03217
695560001577	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
695560001578	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
695560001579	Ligand binding site; other site
695560001580	Putative Catalytic site; other site
695560001581	DXD motif; other site
695560001582	phosphoprotein phosphatases of the metallophosphatase superfamily, metallophosphatase domain; Region: MPP_PPP_family; cd00144
695560001583	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
695560001584	active site
695560001585	metal binding site [ion binding]; metal-binding site
695560001586	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
695560001587	Transposase; Region: DDE_Tnp_ISL3; pfam01610
695560001588	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; cl17295
695560001589	SEC10/PgrA surface exclusion domain; Region: Surf_Exclu_PgrA; TIGR04320
695560001590	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
695560001591	catalytic core [active]
695560001592	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
695560001593	catalytic core [active]
695560001594	Uncharacterized conserved protein [Function unknown]; Region: COG1359
695560001595	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
695560001596	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
695560001597	active site
695560001598	catalytic site [active]
695560001599	Helix-turn-helix domain; Region: HTH_38; pfam13936
695560001600	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
695560001601	DNA-binding interface [nucleotide binding]; DNA binding site
695560001602	Integrase core domain; Region: rve; pfam00665
695560001603	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
695560001604	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
695560001605	Transposase IS200 like; Region: Y1_Tnp; pfam01797
695560001606	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
695560001607	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
695560001608	Probable transposase; Region: OrfB_IS605; pfam01385
695560001609	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
695560001610	magnesium-transporting ATPase; Provisional; Region: PRK15122
695560001611	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
695560001612	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
695560001613	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
695560001614	Soluble P-type ATPase [General function prediction only]; Region: COG4087
695560001615	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
695560001616	Peptidase S8 family domain in Streptococcal C5a peptidases; Region: Peptidases_S8_C5a_Peptidase; cd07475
695560001617	catalytic triad [active]
695560001618	putative active site [active]
695560001619	Fn3-like domain (DUF1034); Region: DUF1034; pfam06280
695560001620	Bacterial surface layer protein; Region: SLAP; pfam03217
695560001621	Bacterial surface layer protein; Region: SLAP; pfam03217
695560001622	aromatic amino acid aminotransferase; Validated; Region: PRK07309
695560001623	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
695560001624	pyridoxal 5'-phosphate binding site [chemical binding]; other site
695560001625	homodimer interface [polypeptide binding]; other site
695560001626	catalytic residue [active]
695560001627	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
695560001628	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
695560001629	Predicted membrane protein, putative toxin regulator [General function prediction only]; Region: PfoR; COG3641
695560001630	Phosphotransferase system, EIIC; Region: PTS_EIIC_2; pfam13303
695560001631	Bacterial surface layer protein; Region: SLAP; pfam03217
695560001632	DNA polymerase IV; Reviewed; Region: PRK03103
695560001633	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
695560001634	active site
695560001635	DNA binding site [nucleotide binding]
695560001636	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
695560001637	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
695560001638	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
695560001639	Probable transposase; Region: OrfB_IS605; pfam01385
695560001640	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
695560001641	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
695560001642	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
695560001643	DNA-binding site [nucleotide binding]; DNA binding site
695560001644	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
695560001645	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
695560001646	dimerization interface [polypeptide binding]; other site
695560001647	putative DNA binding site [nucleotide binding]; other site
695560001648	putative Zn2+ binding site [ion binding]; other site
695560001649	Arsenite efflux pump ACR3 and related permeases [Inorganic ion transport and metabolism]; Region: ACR3; COG0798
695560001650	arsenical-resistance protein; Region: acr3; TIGR00832
695560001651	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
695560001652	Low molecular weight phosphatase family; Region: LMWPc; cd00115
695560001653	active site
695560001654	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
695560001655	Cytidylyltransferase; Region: CTP_transf_2; pfam01467
695560001656	active site
695560001657	nucleotide binding site [chemical binding]; other site
695560001658	HIGH motif; other site
695560001659	KMSKS motif; other site
695560001660	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
695560001661	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
695560001662	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
695560001663	This family is most closely related to the GT1 family of glycosyltransferases. wlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core; Region: GT1_wlbH_like; cd03798
695560001664	nicotinate phosphoribosyltransferase; Validated; Region: PRK09243
695560001665	Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction...; Region: NAPRTase_A; cd01570
695560001666	active site
695560001667	NAD synthetase; Reviewed; Region: nadE; PRK00768
695560001668	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
695560001669	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
695560001670	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
695560001671	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
695560001672	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
695560001673	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
695560001674	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
695560001675	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; Region: Glyphos_transf; pfam04464
695560001676	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
695560001677	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
695560001678	Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128
695560001679	Glycosyltransferase sugar-binding region containing DXD motif; Region: Gly_transf_sug; pfam04488
695560001680	hypothetical protein; Provisional; Region: PRK04351
695560001681	SprT homologues; Region: SprT; cl01182
695560001682	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
695560001683	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
695560001684	Part of AAA domain; Region: AAA_19; pfam13245
695560001685	Family description; Region: UvrD_C_2; pfam13538
695560001686	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
695560001687	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
695560001688	nucleotide binding pocket [chemical binding]; other site
695560001689	K-X-D-G motif; other site
695560001690	catalytic site [active]
695560001691	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
695560001692	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
695560001693	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
695560001694	Dimer interface [polypeptide binding]; other site
695560001695	N-terminal repeat domain of CamS sex pheromone cAM373 precursor; Region: CamS_repeat_1; cd13441
695560001696	putative dimer interface [polypeptide binding]; other site
695560001697	CamS sex pheromone cAM373 precursor; Region: CamS; pfam07537
695560001698	C-terminal repeat domain of CamS sex pheromone cAM373 precursor; Region: CamS_repeat_2; cd13440
695560001699	putative dimer interface [polypeptide binding]; other site
695560001700	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
695560001701	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
695560001702	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
695560001703	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
695560001704	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
695560001705	GatB domain; Region: GatB_Yqey; smart00845
695560001706	putative lipid kinase; Reviewed; Region: PRK13337
695560001707	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
695560001708	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
695560001709	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
695560001710	Na+/H+ antiporter NhaC; Region: antiport_nhaC; TIGR00931
695560001711	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
695560001712	Predicted RNA-binding protein, contains TRAM domain [General function prediction only]; Region: COG3269
695560001713	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
695560001714	S-adenosylmethionine binding site [chemical binding]; other site
695560001715	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
695560001716	Coenzyme A binding pocket [chemical binding]; other site
695560001717	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
695560001718	Major Facilitator Superfamily; Region: MFS_1; pfam07690
695560001719	putative substrate translocation pore; other site
695560001720	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
695560001721	potential frameshift: common BLAST hit: gi|295692419|ref|YP_003601029.1| transcriptional regulator
695560001722	myosin-cross-reactive antigen; Provisional; Region: PRK13977
695560001723	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
695560001724	Coenzyme A binding pocket [chemical binding]; other site
695560001725	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
695560001726	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
695560001727	non-specific DNA binding site [nucleotide binding]; other site
695560001728	salt bridge; other site
695560001729	sequence-specific DNA binding site [nucleotide binding]; other site
695560001730	Protein of unknown function (DUF3955); Region: DUF3955; pfam13127
695560001731	Helix-turn-helix domain; Region: HTH_19; pfam12844
695560001732	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
695560001733	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
695560001734	active site
695560001735	catalytic tetrad [active]
695560001736	uracil transporter; Provisional; Region: PRK10720
695560001737	Sulfate transporter family; Region: Sulfate_transp; pfam00916
695560001738	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
695560001739	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
695560001740	active site
695560001741	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
695560001742	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
695560001743	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
695560001744	Major Facilitator Superfamily; Region: MFS_1; pfam07690
695560001745	putative substrate translocation pore; other site
695560001746	drug efflux system protein MdtG; Provisional; Region: PRK09874
695560001747	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
695560001748	putative substrate translocation pore; other site
695560001749	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
695560001750	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
695560001751	oligomer interface [polypeptide binding]; other site
695560001752	active site
695560001753	metal binding site [ion binding]; metal-binding site
695560001754	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
695560001755	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
695560001756	Walker A/P-loop; other site
695560001757	ATP binding site [chemical binding]; other site
695560001758	Q-loop/lid; other site
695560001759	ABC transporter signature motif; other site
695560001760	Walker B; other site
695560001761	D-loop; other site
695560001762	H-loop/switch region; other site
695560001763	ABC transporter; Region: ABC_tran_2; pfam12848
695560001764	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
695560001765	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
695560001766	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
695560001767	active site
695560001768	catalytic tetrad [active]
695560001769	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
695560001770	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
695560001771	substrate binding pocket [chemical binding]; other site
695560001772	membrane-bound complex binding site; other site
695560001773	hinge residues; other site
695560001774	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
695560001775	Transcriptional regulators [Transcription]; Region: MarR; COG1846
695560001776	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
695560001777	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
695560001778	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
695560001779	Walker A/P-loop; other site
695560001780	ATP binding site [chemical binding]; other site
695560001781	Q-loop/lid; other site
695560001782	ABC transporter signature motif; other site
695560001783	Walker B; other site
695560001784	D-loop; other site
695560001785	H-loop/switch region; other site
695560001786	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
695560001787	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
695560001788	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
695560001789	Walker A/P-loop; other site
695560001790	ATP binding site [chemical binding]; other site
695560001791	Q-loop/lid; other site
695560001792	ABC transporter signature motif; other site
695560001793	Walker B; other site
695560001794	D-loop; other site
695560001795	H-loop/switch region; other site
695560001796	ABC-type cobalt transport system, permease component; Region: ABC_cobalt; pfam09819
695560001797	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
695560001798	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
695560001799	Sugar specificity; other site
695560001800	Pyrimidine base specificity; other site
695560001801	ATP-binding site [chemical binding]; other site
695560001802	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
695560001803	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
695560001804	Walker A/P-loop; other site
695560001805	ATP binding site [chemical binding]; other site
695560001806	Q-loop/lid; other site
695560001807	ABC transporter signature motif; other site
695560001808	Walker B; other site
695560001809	D-loop; other site
695560001810	H-loop/switch region; other site
695560001811	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
695560001812	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
695560001813	substrate binding pocket [chemical binding]; other site
695560001814	membrane-bound complex binding site; other site
695560001815	hinge residues; other site
695560001816	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
695560001817	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
695560001818	dimer interface [polypeptide binding]; other site
695560001819	conserved gate region; other site
695560001820	putative PBP binding loops; other site
695560001821	ABC-ATPase subunit interface; other site
695560001822	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
695560001823	dimer interface [polypeptide binding]; other site
695560001824	conserved gate region; other site
695560001825	putative PBP binding loops; other site
695560001826	ABC-ATPase subunit interface; other site
695560001827	Protein of unknown function (DUF2974); Region: DUF2974; pfam11187
695560001828	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
695560001829	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
695560001830	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
695560001831	HIT family: HIT (Histidine triad) proteins, named for a motif related to the sequence HxHxH/Qxx (x, a hydrophobic amino acid), are a superfamily of nucleotide hydrolases and transferases, which act on the alpha-phosphate of ribonucleotides. On the basis...; Region: HIT_like; cl00228
695560001832	nucleotide binding site/active site [active]
695560001833	HIT family signature motif; other site
695560001834	catalytic residue [active]
695560001835	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
695560001836	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
695560001837	substrate binding site [chemical binding]; other site
695560001838	dimer interface [polypeptide binding]; other site
695560001839	ATP binding site [chemical binding]; other site
695560001840	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
695560001841	tetramer (dimer of dimers) interface [polypeptide binding]; other site
695560001842	active site
695560001843	dimer interface [polypeptide binding]; other site
695560001844	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
695560001845	Helix-turn-helix domain; Region: HTH_38; pfam13936
695560001846	Integrase core domain; Region: rve; pfam00665
695560001847	K+ potassium transporter; Region: K_trans; pfam02705
695560001848	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
695560001849	active site
695560001850	tetramer interface [polypeptide binding]; other site
695560001851	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
695560001852	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
695560001853	DNA-binding site [nucleotide binding]; DNA binding site
695560001854	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
695560001855	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
695560001856	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
695560001857	Enterocin A Immunity; Region: EntA_Immun; pfam08951
695560001858	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
695560001859	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
695560001860	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
695560001861	putative phosphoketolase; Provisional; Region: PRK05261
695560001862	Thiamine pyrophosphate (TPP) family, Phosphoketolase (PK) subfamily, TPP-binding module; PK catalyzes the conversion of D-xylulose 5-phosphate and phosphate to acetyl phosphate, D-glyceraldehyde-3-phosphate and H2O. This enzyme requires divalent...; Region: TPP_PK; cd02011
695560001863	TPP-binding site; other site
695560001864	XFP C-terminal domain; Region: XFP_C; pfam09363
695560001865	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
695560001866	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
695560001867	active site
695560001868	nucleophile elbow; other site
695560001869	CAAX protease self-immunity; Region: Abi; cl00558
695560001870	PTS system, alpha-glucoside-specific IIBC component; Region: PTS-IIBC-alpha; TIGR02005
695560001871	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
695560001872	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
695560001873	active site turn [active]
695560001874	phosphorylation site [posttranslational modification]
695560001875	Phosphotransferase system IIB components [Carbohydrate transport and metabolism]; Region: PtsG; COG1264
695560001876	active site turn [active]
695560001877	phosphorylation site [posttranslational modification]
695560001878	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
695560001879	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
695560001880	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
695560001881	putative active site [active]
695560001882	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
695560001883	HPr interaction site; other site
695560001884	glycerol kinase (GK) interaction site [polypeptide binding]; other site
695560001885	active site
695560001886	phosphorylation site [posttranslational modification]
695560001887	IncA protein; Region: IncA; pfam04156
695560001888	Nitroreductase family. Members of this family utilize FMN as a cofactor and catalyze reduction of a variety of nitroaromatic compounds, including nitrofurans, nitrobenzens, nitrophenol, nitrobenzoate and quinones by using either NADH or NADPH as a source...; Region: Nitroreductase; cd02136
695560001889	putative FMN binding site [chemical binding]; other site
695560001890	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
695560001891	Domain of unknown function DUF21; Region: DUF21; pfam01595
695560001892	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
695560001893	Transporter associated domain; Region: CorC_HlyC; smart01091
695560001894	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
695560001895	active site
695560001896	Amino acid permease; Region: AA_permease_2; pfam13520
695560001897	Endo-N-acetylmuramidases (muramidases) are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues; Region: GH25_muramidase; cl10448
695560001898	active site
695560001899	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
695560001900	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
695560001901	DEAD-like helicases superfamily; Region: DEXDc; smart00487
695560001902	ATP binding site [chemical binding]; other site
695560001903	putative Mg++ binding site [ion binding]; other site
695560001904	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
695560001905	nucleotide binding region [chemical binding]; other site
695560001906	ATP-binding site [chemical binding]; other site
695560001907	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
695560001908	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
695560001909	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
695560001910	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
695560001911	active site
695560001912	homodimer interface [polypeptide binding]; other site
695560001913	Predicted membrane protein [Function unknown]; Region: COG2246
695560001914	GtrA-like protein; Region: GtrA; pfam04138
695560001915	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
695560001916	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
695560001917	methionine aminopeptidase; Provisional; Region: PRK08671
695560001918	active site
695560001919	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
695560001920	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
695560001921	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
695560001922	active site
695560001923	tetramer interface; other site
695560001924	putative acyltransferase; Provisional; Region: PRK05790
695560001925	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
695560001926	dimer interface [polypeptide binding]; other site
695560001927	active site
695560001928	Class II hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR); Region: HMG-CoA_reductase_classII; cd00644
695560001929	homodimer interface [polypeptide binding]; other site
695560001930	catalytic residues [active]
695560001931	NAD binding site [chemical binding]; other site
695560001932	substrate binding pocket [chemical binding]; other site
695560001933	flexible flap; other site
695560001934	3-hydroxy-3-methylglutaryl CoA synthase, prokaryotic clade; Region: HMG-CoA-S_prok; TIGR01835
695560001935	"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are...; Region: init_cond_enzymes; cd00827
695560001936	dimer interface [polypeptide binding]; other site
695560001937	active site
695560001938	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
695560001939	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
695560001940	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
695560001941	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
695560001942	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
695560001943	S-adenosylmethionine binding site [chemical binding]; other site
695560001944	recombination regulator RecX; Provisional; Region: recX; PRK14135
695560001945	Flavoprotein; Region: Flavoprotein; cl08021
695560001946	FOG: CBS domain [General function prediction only]; Region: COG0517
695560001947	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
695560001948	Transporter associated domain; Region: CorC_HlyC; pfam03471
695560001949	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
695560001950	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
695560001951	G1 box; other site
695560001952	putative GEF interaction site [polypeptide binding]; other site
695560001953	GTP/Mg2+ binding site [chemical binding]; other site
695560001954	Switch I region; other site
695560001955	G2 box; other site
695560001956	G3 box; other site
695560001957	Switch II region; other site
695560001958	G4 box; other site
695560001959	G5 box; other site
695560001960	Translation_Factor_II_like: Elongation factor Tu (EF-Tu) domain II-like proteins. Elongation factor Tu consists of three structural domains, this family represents the second domain. Domain II adopts a beta barrel structure and is involved in binding to...; Region: Translation_Factor_II_like; cl02787
695560001961	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
695560001962	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
695560001963	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
695560001964	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
695560001965	Domain of unknown function (DUF1827); Region: DUF1827; pfam08860
695560001966	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
695560001967	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
695560001968	Walker A motif; other site
695560001969	ATP binding site [chemical binding]; other site
695560001970	Walker B motif; other site
695560001971	arginine finger; other site
695560001972	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
695560001973	Walker A motif; other site
695560001974	ATP binding site [chemical binding]; other site
695560001975	Walker B motif; other site
695560001976	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
695560001977	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
695560001978	dimerization domain swap beta strand [polypeptide binding]; other site
695560001979	regulatory protein interface [polypeptide binding]; other site
695560001980	active site
695560001981	regulatory phosphorylation site [posttranslational modification]; other site
695560001982	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
695560001983	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
695560001984	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
695560001985	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
695560001986	Arsenate Reductase (ArsC) family, Spx subfamily; Spx is a unique RNA polymerase (RNAP)-binding protein present in bacilli and some mollicutes. It inhibits transcription by binding to the C-terminal domain of the alpha subunit of RNAP, disrupting complex...; Region: ArsC_Spx; cd03032
695560001987	ArsC family; Region: ArsC; pfam03960
695560001988	putative catalytic residues [active]
695560001989	thiol/disulfide switch; other site
695560001990	adaptor protein; Provisional; Region: PRK02315
695560001991	Competence protein CoiA-like family; Region: CoiA; cl11541
695560001992	Thioredoxin; Region: Thioredoxin_5; pfam13743
695560001993	Uncharacterized subgroup 1 of the CYTH-like superfamily; Region: CYTH-like_Pase_1; cd07762
695560001994	putative active site [active]
695560001995	putative metal binding residues [ion binding]; other site
695560001996	signature motif; other site
695560001997	putative triphosphate binding site [ion binding]; other site
695560001998	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
695560001999	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
695560002000	synthetase active site [active]
695560002001	NTP binding site [chemical binding]; other site
695560002002	metal binding site [ion binding]; metal-binding site
695560002003	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK04885
695560002004	ATP-NAD kinase; Region: NAD_kinase; pfam01513
695560002005	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
695560002006	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
695560002007	active site
695560002008	myosin-cross-reactive antigen; Provisional; Region: PRK13977
695560002009	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
695560002010	Lactonase, 7-bladed beta-propeller; Region: Lactonase; pfam10282
695560002011	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
695560002012	active site
695560002013	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
695560002014	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
695560002015	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
695560002016	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
695560002017	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
695560002018	active site
695560002019	motif I; other site
695560002020	motif II; other site
695560002021	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
695560002022	PTS system glucitol/sorbitol-specific IIA component; Region: PTSIIA_gutA; cl01516
695560002023	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
695560002024	Domain of unknown function DUF20; Region: UPF0118; pfam01594
695560002025	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
695560002026	Protein of unknown function (DUF1149); Region: DUF1149; cl11551
695560002027	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
695560002028	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
695560002029	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
695560002030	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
695560002031	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
695560002032	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
695560002033	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
695560002034	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
695560002035	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
695560002036	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
695560002037	classical (c) SDRs; Region: SDR_c; cd05233
695560002038	NAD(P) binding site [chemical binding]; other site
695560002039	active site
695560002040	Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown]; Region: COG1426
695560002041	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
695560002042	non-specific DNA binding site [nucleotide binding]; other site
695560002043	salt bridge; other site
695560002044	sequence-specific DNA binding site [nucleotide binding]; other site
695560002045	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
695560002046	recombinase A; Provisional; Region: recA; PRK09354
695560002047	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
695560002048	hexamer interface [polypeptide binding]; other site
695560002049	Walker A motif; other site
695560002050	ATP binding site [chemical binding]; other site
695560002051	Walker B motif; other site
695560002052	phosphodiesterase; Provisional; Region: PRK12704
695560002053	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
695560002054	Zn2+ binding site [ion binding]; other site
695560002055	Mg2+ binding site [ion binding]; other site
695560002056	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
695560002057	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
695560002058	Mg++ binding site [ion binding]; other site
695560002059	putative catalytic motif [active]
695560002060	substrate binding site [chemical binding]; other site
695560002061	Uncharacterized conserved protein [Function unknown]; Region: COG1739
695560002062	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
695560002063	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
695560002064	Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein) [DNA replication, recombination, and repair]; Region: comFA; COG4098
695560002065	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
695560002066	ATP binding site [chemical binding]; other site
695560002067	putative Mg++ binding site [ion binding]; other site
695560002068	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
695560002069	nucleotide binding region [chemical binding]; other site
695560002070	ATP-binding site [chemical binding]; other site
695560002071	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
695560002072	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
695560002073	active site
695560002074	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
695560002075	30S subunit binding site; other site
695560002076	preprotein translocase subunit SecA; Reviewed; Region: secA; PRK12906
695560002077	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
695560002078	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
695560002079	nucleotide binding region [chemical binding]; other site
695560002080	ATP-binding site [chemical binding]; other site
695560002081	peptide chain release factor 2; Provisional; Region: PRK05589
695560002082	This domain is found in peptide chain release factors; Region: PCRF; smart00937
695560002083	RF-1 domain; Region: RF-1; pfam00472
695560002084	HPr kinase/phosphorylase; Provisional; Region: PRK05428
695560002085	HPr Serine kinase N terminus; Region: Hpr_kinase_N; pfam02603
695560002086	HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent...; Region: HprK_C; cd01918
695560002087	Hpr binding site; other site
695560002088	active site
695560002089	homohexamer subunit interaction site [polypeptide binding]; other site
695560002090	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK12437
695560002091	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
695560002092	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
695560002093	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
695560002094	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
695560002095	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
695560002096	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
695560002097	glycogen branching enzyme; Provisional; Region: PRK12313
695560002098	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
695560002099	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
695560002100	active site
695560002101	catalytic site [active]
695560002102	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
695560002103	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK05293
695560002104	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
695560002105	ligand binding site; other site
695560002106	oligomer interface; other site
695560002107	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
695560002108	dimer interface [polypeptide binding]; other site
695560002109	N-terminal domain interface [polypeptide binding]; other site
695560002110	sulfate 1 binding site; other site
695560002111	glucose-1-phosphate adenylyltransferase, GlgD subunit; Region: glgD; TIGR02092
695560002112	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
695560002113	active site
695560002114	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
695560002115	dimer interface [polypeptide binding]; other site
695560002116	N-terminal domain interface [polypeptide binding]; other site
695560002117	sulfate 1 binding site; other site
695560002118	glycogen synthase; Provisional; Region: glgA; PRK00654
695560002119	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
695560002120	ADP-binding pocket [chemical binding]; other site
695560002121	homodimer interface [polypeptide binding]; other site
695560002122	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
695560002123	homodimer interface [polypeptide binding]; other site
695560002124	glycogen/starch/alpha-glucan phosphorylases; Region: P_ylase; TIGR02093
695560002125	active site pocket [active]
695560002126	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
695560002127	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
695560002128	active site
695560002129	homodimer interface [polypeptide binding]; other site
695560002130	catalytic site [active]
695560002131	phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150
695560002132	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
695560002133	active site
695560002134	substrate binding site [chemical binding]; other site
695560002135	metal binding site [ion binding]; metal-binding site
695560002136	excinuclease ABC subunit B; Provisional; Region: PRK05298
695560002137	Myosin and Kinesin motor domain. These ATPases belong to the P-loop NTPase family and provide the driving force in myosin and kinesin mediated processes; Region: Motor_domain; cl00286
695560002138	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
695560002139	ATP-binding site [chemical binding]; other site
695560002140	ATP binding site [chemical binding]; other site
695560002141	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
695560002142	nucleotide binding region [chemical binding]; other site
695560002143	ATP-binding site [chemical binding]; other site
695560002144	Ultra-violet resistance protein B; Region: UvrB; pfam12344
695560002145	UvrB/uvrC motif; Region: UVR; pfam02151
695560002146	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
695560002147	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
695560002148	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
695560002149	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
695560002150	Short repeat of unknown function (DUF308); Region: DUF308; cl15828
695560002151	glmZ(sRNA)-inactivating NTPase; Provisional; Region: PRK05416
695560002152	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
695560002153	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
695560002154	phosphate binding site [ion binding]; other site
695560002155	putative substrate binding pocket [chemical binding]; other site
695560002156	dimer interface [polypeptide binding]; other site
695560002157	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1481
695560002158	Sporulation Regulator WhiA N terminal; Region: WhiA_N; pfam10298
695560002159	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
695560002160	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
695560002161	oligomer interface [polypeptide binding]; other site
695560002162	active site residues [active]
695560002163	SH3-like domain; Region: SH3_8; pfam13457
695560002164	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
695560002165	inner membrane transporter YjeM; Provisional; Region: PRK15238
695560002166	Helix-turn-helix domain; Region: HTH_38; pfam13936
695560002167	Bacteriophage T4-like capsid assembly protein (Gp20); Region: Phage_T4_Gp20; pfam07230
695560002168	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
695560002169	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
695560002170	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
695560002171	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
695560002172	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
695560002173	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
695560002174	Phosphoglycerate kinase; Region: PGK; pfam00162
695560002175	substrate binding site [chemical binding]; other site
695560002176	hinge regions; other site
695560002177	ADP binding site [chemical binding]; other site
695560002178	catalytic site [active]
695560002179	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
695560002180	triosephosphate isomerase; Provisional; Region: PRK14567
695560002181	substrate binding site [chemical binding]; other site
695560002182	dimer interface [polypeptide binding]; other site
695560002183	catalytic triad [active]
695560002184	Transposase; Region: DEDD_Tnp_IS110; pfam01548
695560002185	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
695560002186	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
695560002187	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
695560002188	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
695560002189	active site
695560002190	motif I; other site
695560002191	motif II; other site
695560002192	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
695560002193	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
695560002194	ligand binding site [chemical binding]; other site
695560002195	active site
695560002196	UGI interface [polypeptide binding]; other site
695560002197	catalytic site [active]
695560002198	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
695560002199	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
695560002200	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
695560002201	Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; Region: PTPc; cl00053
695560002202	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
695560002203	Probable transposase; Region: OrfB_IS605; pfam01385
695560002204	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
695560002205	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
695560002206	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
695560002207	an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III; Region: DNA_pol_III_epsilon_like; cd06130
695560002208	active site
695560002209	catalytic site [active]
695560002210	substrate binding site [chemical binding]; other site
695560002211	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
695560002212	FAD binding domain; Region: FAD_binding_4; pfam01565
695560002213	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
695560002214	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
695560002215	ATP-binding cassette domain of the polyamine transporter; Region: ABC_PotA_N; cd03300
695560002216	Walker A/P-loop; other site
695560002217	ATP binding site [chemical binding]; other site
695560002218	Q-loop/lid; other site
695560002219	ABC transporter signature motif; other site
695560002220	Walker B; other site
695560002221	D-loop; other site
695560002222	H-loop/switch region; other site
695560002223	TOBE domain; Region: TOBE_2; pfam08402
695560002224	ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]; Region: UgpA; COG1175
695560002225	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
695560002226	putative PBP binding loops; other site
695560002227	ABC-ATPase subunit interface; other site
695560002228	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
695560002229	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
695560002230	dimer interface [polypeptide binding]; other site
695560002231	conserved gate region; other site
695560002232	putative PBP binding loops; other site
695560002233	ABC-ATPase subunit interface; other site
695560002234	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
695560002235	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
695560002236	Uncharacterized conserved protein [Function unknown]; Region: COG1624
695560002237	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
695560002238	YbbR-like protein; Region: YbbR; pfam07949
695560002239	YbbR-like protein; Region: YbbR; pfam07949
695560002240	YbbR-like protein; Region: YbbR; pfam07949
695560002241	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14316
695560002242	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
695560002243	active site
695560002244	substrate binding site [chemical binding]; other site
695560002245	metal binding site [ion binding]; metal-binding site
695560002246	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
695560002247	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
695560002248	active site
695560002249	motif I; other site
695560002250	motif II; other site
695560002251	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
695560002252	sugar phosphate phosphatase; Provisional; Region: PRK10513
695560002253	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
695560002254	active site
695560002255	motif I; other site
695560002256	motif II; other site
695560002257	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
695560002258	Low molecular weight phosphatase family; Region: LMWPc; cl00105
695560002259	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
695560002260	potential frameshift: common BLAST hit: gi|58337041|ref|YP_193626.1| transcription antiterminator
695560002261	potential frameshift: common BLAST hit: gi|58337042|ref|YP_193627.1| phosphotransferase system enzyme II
695560002262	potential frameshift: common BLAST hit: gi|58337042|ref|YP_193627.1| phosphotransferase system enzyme II
695560002263	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
695560002264	beta-galactosidase; Region: BGL; TIGR03356
695560002265	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
695560002266	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
695560002267	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
695560002268	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
695560002269	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
695560002270	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
695560002271	Amino acid permease; Region: AA_permease_2; pfam13520
695560002272	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08061
695560002273	VanZ like family; Region: VanZ; cl01971
695560002274	hypothetical protein; Validated; Region: PRK00110
695560002275	Type II/IV secretion system protein; Region: T2SE; pfam00437
695560002276	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
695560002277	Walker A motif; other site
695560002278	ATP binding site [chemical binding]; other site
695560002279	Walker B motif; other site
695560002280	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
695560002281	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
695560002282	Competence protein ComGC [Intracellular trafficking and secretion]; Region: ComGC; COG4537
695560002283	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827
695560002284	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
695560002285	S-adenosylmethionine binding site [chemical binding]; other site
695560002286	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
695560002287	propionate/acetate kinase; Provisional; Region: PRK12379
695560002288	Protein of unknown function (DUF3737); Region: DUF3737; pfam12541
695560002289	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
695560002290	Int/Topo IB signature motif; other site
695560002291	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
695560002292	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
695560002293	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
695560002294	non-specific DNA binding site [nucleotide binding]; other site
695560002295	salt bridge; other site
695560002296	sequence-specific DNA binding site [nucleotide binding]; other site
695560002297	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
695560002298	Helix-turn-helix domain; Region: HTH_17; pfam12728
695560002299	Helix-turn-helix domain; Region: HTH_36; pfam13730
695560002300	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
695560002301	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
695560002302	Walker A motif; other site
695560002303	ATP binding site [chemical binding]; other site
695560002304	Walker B motif; other site
695560002305	DEAD-like helicases superfamily; Region: DEXDc; smart00487
695560002306	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
695560002307	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
695560002308	ATP binding site [chemical binding]; other site
695560002309	putative Mg++ binding site [ion binding]; other site
695560002310	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
695560002311	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
695560002312	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
695560002313	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
695560002314	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
695560002315	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
695560002316	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
695560002317	Mrr N-terminal domain; Region: Mrr_N; pfam14338
695560002318	Restriction endonuclease; Region: Mrr_cat; pfam04471
695560002319	Protein of unknown function (DUF3737); Region: DUF3737; pfam12541
695560002320	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
695560002321	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
695560002322	pyridoxal 5'-phosphate binding site [chemical binding]; other site
695560002323	homodimer interface [polypeptide binding]; other site
695560002324	catalytic residue [active]
695560002325	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
695560002326	mannose-6-phosphate isomerase, class I; Region: manA; TIGR00218
695560002327	SdpI/YhfL protein family; Region: SdpI; pfam13630
695560002328	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
695560002329	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
695560002330	active site
695560002331	phosphorylation site [posttranslational modification]
695560002332	intermolecular recognition site; other site
695560002333	dimerization interface [polypeptide binding]; other site
695560002334	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
695560002335	DNA binding site [nucleotide binding]
695560002336	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
695560002337	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
695560002338	dimerization interface [polypeptide binding]; other site
695560002339	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
695560002340	dimer interface [polypeptide binding]; other site
695560002341	phosphorylation site [posttranslational modification]
695560002342	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
695560002343	ATP binding site [chemical binding]; other site
695560002344	Mg2+ binding site [ion binding]; other site
695560002345	G-X-G motif; other site
695560002346	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
695560002347	Sulfatase; Region: Sulfatase; pfam00884
695560002348	VanZ like family; Region: VanZ; pfam04892
695560002349	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14097
695560002350	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
695560002351	active site
695560002352	dimer interface [polypeptide binding]; other site
695560002353	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
695560002354	dimer interface [polypeptide binding]; other site
695560002355	active site
695560002356	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
695560002357	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
695560002358	putative substrate translocation pore; other site
695560002359	Beta-lactamase; Region: Beta-lactamase; pfam00144
695560002360	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
695560002361	UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurE; COG0769
695560002362	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
695560002363	Domain of unknown function (DUF1727); Region: DUF1727; pfam08353
695560002364	thymidine kinase; Provisional; Region: PRK04296
695560002365	peptide chain release factor 1; Validated; Region: prfA; PRK00591
695560002366	This domain is found in peptide chain release factors; Region: PCRF; smart00937
695560002367	RF-1 domain; Region: RF-1; pfam00472
695560002368	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
695560002369	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
695560002370	S-adenosylmethionine binding site [chemical binding]; other site
695560002371	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
695560002372	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
695560002373	Putative GTP-binding controlling metal-binding; Region: SUA5; pfam03481
695560002374	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
695560002375	active site
695560002376	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
695560002377	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
695560002378	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
695560002379	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
695560002380	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
695560002381	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
695560002382	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
695560002383	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
695560002384	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
695560002385	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
695560002386	beta subunit interaction interface [polypeptide binding]; other site
695560002387	Walker A motif; other site
695560002388	ATP binding site [chemical binding]; other site
695560002389	Walker B motif; other site
695560002390	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
695560002391	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
695560002392	core domain interface [polypeptide binding]; other site
695560002393	delta subunit interface [polypeptide binding]; other site
695560002394	epsilon subunit interface [polypeptide binding]; other site
695560002395	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
695560002396	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
695560002397	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
695560002398	alpha subunit interaction interface [polypeptide binding]; other site
695560002399	Walker A motif; other site
695560002400	ATP binding site [chemical binding]; other site
695560002401	Walker B motif; other site
695560002402	inhibitor binding site; inhibition site
695560002403	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
695560002404	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
695560002405	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
695560002406	gamma subunit interface [polypeptide binding]; other site
695560002407	epsilon subunit interface [polypeptide binding]; other site
695560002408	LBP interface [polypeptide binding]; other site
695560002409	Protein of unknown function (DUF1146); Region: DUF1146; cl11486
695560002410	rod shape-determining protein MreB; Provisional; Region: PRK13930
695560002411	MreB and similar proteins; Region: MreB_like; cd10225
695560002412	nucleotide binding site [chemical binding]; other site
695560002413	Mg binding site [ion binding]; other site
695560002414	putative protofilament interaction site [polypeptide binding]; other site
695560002415	RodZ interaction site [polypeptide binding]; other site
695560002416	hypothetical protein; Provisional; Region: PRK14379
695560002417	Protein of unknown function (DUF2969); Region: DUF2969; pfam11184
695560002418	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
695560002419	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
695560002420	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
695560002421	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
695560002422	Ligand Binding Site [chemical binding]; other site
695560002423	recombination factor protein RarA; Reviewed; Region: PRK13342
695560002424	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
695560002425	Walker A motif; other site
695560002426	ATP binding site [chemical binding]; other site
695560002427	Walker B motif; other site
695560002428	arginine finger; other site
695560002429	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
695560002430	Protein of unknown function (DUF1694); Region: DUF1694; pfam07997
695560002431	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
695560002432	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
695560002433	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
695560002434	RNA binding surface [nucleotide binding]; other site
695560002435	septation ring formation regulator EzrA; Provisional; Region: PRK04778
695560002436	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
695560002437	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
695560002438	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
695560002439	catalytic residue [active]
695560002440	thiamine biosynthesis protein ThiI; Provisional; Region: PRK01565
695560002441	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
695560002442	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
695560002443	Ligand Binding Site [chemical binding]; other site
695560002444	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
695560002445	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
695560002446	non-specific DNA binding site [nucleotide binding]; other site
695560002447	salt bridge; other site
695560002448	sequence-specific DNA binding site [nucleotide binding]; other site
695560002449	Transposase, Mutator family; Region: Transposase_mut; pfam00872
695560002450	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
695560002451	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
695560002452	RNA binding surface [nucleotide binding]; other site
695560002453	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
695560002454	active site
695560002455	uracil binding [chemical binding]; other site
695560002456	Predicted membrane protein [Function unknown]; Region: COG2246
695560002457	GtrA-like protein; Region: GtrA; pfam04138
695560002458	FMN-binding domain; Region: FMN_bind; pfam04205
695560002459	flavocytochrome c; Region: flavo_cyto_c; TIGR01813
695560002460	L-aspartate oxidase; Provisional; Region: PRK06175
695560002461	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
695560002462	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
695560002463	active site
695560002464	HIGH motif; other site
695560002465	nucleotide binding site [chemical binding]; other site
695560002466	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
695560002467	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
695560002468	active site
695560002469	KMSKS motif; other site
695560002470	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
695560002471	tRNA binding surface [nucleotide binding]; other site
695560002472	anticodon binding site; other site
695560002473	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
695560002474	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
695560002475	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
695560002476	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
695560002477	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
695560002478	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
695560002479	motif II; other site
695560002480	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
695560002481	MPN+ (JAMM) motif; other site
695560002482	Zinc-binding site [ion binding]; other site
695560002483	rod shape-determining protein MreB; Provisional; Region: PRK13927
695560002484	MreB and similar proteins; Region: MreB_like; cd10225
695560002485	nucleotide binding site [chemical binding]; other site
695560002486	Mg binding site [ion binding]; other site
695560002487	putative protofilament interaction site [polypeptide binding]; other site
695560002488	RodZ interaction site [polypeptide binding]; other site
695560002489	rod shape-determining protein MreC; Provisional; Region: PRK13922
695560002490	rod shape-determining protein MreC; Region: MreC; pfam04085
695560002491	rod shape-determining protein MreD; Region: shape_MreD; TIGR03426
695560002492	Protein of unknown function (DUF4044); Region: DUF4044; pfam13253
695560002493	Protein of unknown function (DUF3397); Region: DUF3397; pfam11877
695560002494	cell division protein MraZ; Reviewed; Region: PRK00326
695560002495	MraZ protein; Region: MraZ; pfam02381
695560002496	MraZ protein; Region: MraZ; pfam02381
695560002497	MraW methylase family; Region: Methyltransf_5; pfam01795
695560002498	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
695560002499	Cell division protein FtsL; Region: FtsL; cl11433
695560002500	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
695560002501	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
695560002502	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
695560002503	PASTA domain. This domain is found at the C-termini of several Penicillin-binding proteins (PBPs) and bacterial serine/threonine kinases. It is a small globular fold consisting of 3 beta-sheets and an alpha-helix. The name PASTA is derived from PBP and...; Region: PASTA; cl02768
695560002504	PASTA domain of PBP2x-like proteins, second repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_2; cd06575
695560002505	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
695560002506	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
695560002507	Mg++ binding site [ion binding]; other site
695560002508	putative catalytic motif [active]
695560002509	putative substrate binding site [chemical binding]; other site
695560002510	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK02472
695560002511	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
695560002512	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
695560002513	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
695560002514	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
695560002515	active site
695560002516	homodimer interface [polypeptide binding]; other site
695560002517	Cell division protein FtsQ; Region: FtsQ; pfam03799
695560002518	Cell division ATPase FtsA [Cell division and chromosome partitioning]; Region: ftsA; COG0849
695560002519	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
695560002520	nucleotide binding site [chemical binding]; other site
695560002521	Cell division protein FtsA; Region: FtsA; cl17206
695560002522	Cell division protein FtsA; Region: FtsA; pfam14450
695560002523	cell division protein FtsZ; Validated; Region: PRK09330
695560002524	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
695560002525	nucleotide binding site [chemical binding]; other site
695560002526	SulA interaction site; other site
695560002527	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1799
695560002528	YGGT family; Region: YGGT; pfam02325
695560002529	Uncharacterized conserved protein, contains S4-like domain [Function unknown]; Region: COG2302
695560002530	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
695560002531	RNA binding surface [nucleotide binding]; other site
695560002532	DivIVA protein; Region: DivIVA; pfam05103
695560002533	DivIVA domain; Region: DivI1A_domain; TIGR03544
695560002534	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
695560002535	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
695560002536	active site
695560002537	HIGH motif; other site
695560002538	nucleotide binding site [chemical binding]; other site
695560002539	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
695560002540	active site
695560002541	KMSKS motif; other site
695560002542	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
695560002543	tRNA binding surface [nucleotide binding]; other site
695560002544	anticodon binding site; other site
695560002545	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
695560002546	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
695560002547	DNA-binding site [nucleotide binding]; DNA binding site
695560002548	RNA-binding motif; other site
695560002549	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
695560002550	dimer interface [polypeptide binding]; other site
695560002551	ADP-ribose binding site [chemical binding]; other site
695560002552	active site
695560002553	nudix motif; other site
695560002554	metal binding site [ion binding]; metal-binding site
695560002555	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
695560002556	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
695560002557	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
695560002558	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
695560002559	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
695560002560	catalytic residue [active]
695560002561	Putative amino acid metabolism; Region: DUF1831; pfam08866
695560002562	tRNA methyl transferase; Region: tRNA_Me_trans; pfam03054
695560002563	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
695560002564	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
695560002565	catalytic core [active]
695560002566	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
695560002567	binding surface
695560002568	TPR motif; other site
695560002569	Anaphase-promoting complex, cyclosome, subunit 3; Region: Apc3; pfam12895
695560002570	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
695560002571	AAA domain; Region: AAA_30; pfam13604
695560002572	Family description; Region: UvrD_C_2; pfam13538
695560002573	Nuclease-related domain; Region: NERD; pfam08378
695560002574	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
695560002575	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
695560002576	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
695560002577	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
695560002578	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
695560002579	hypothetical protein; Provisional; Region: PRK13667
695560002580	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
695560002581	active site
695560002582	catalytic residues [active]
695560002583	metal binding site [ion binding]; metal-binding site
695560002584	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
695560002585	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
695560002586	G1 box; other site
695560002587	putative GEF interaction site [polypeptide binding]; other site
695560002588	GTP/Mg2+ binding site [chemical binding]; other site
695560002589	Switch I region; other site
695560002590	G2 box; other site
695560002591	G3 box; other site
695560002592	Switch II region; other site
695560002593	G4 box; other site
695560002594	G5 box; other site
695560002595	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
695560002596	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
695560002597	cell division protein FtsW; Region: ftsW; TIGR02614
695560002598	Uncharacterized protein conserved in bacteria (DUF2129); Region: DUF2129; pfam09902
695560002599	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
695560002600	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
695560002601	S-adenosylmethionine binding site [chemical binding]; other site
695560002602	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
695560002603	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
695560002604	active site
695560002605	(T/H)XGH motif; other site
695560002606	Predicted secreted protein containing a PDZ domain [Signal transduction mechanisms]; Region: SdrC; COG3480
695560002607	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
695560002608	SLBB domain; Region: SLBB; pfam10531
695560002609	comEA protein; Region: comE; TIGR01259
695560002610	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786
695560002611	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
695560002612	Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658
695560002613	Competence protein; Region: Competence; pfam03772
695560002614	Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333
695560002615	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
695560002616	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
695560002617	DNA polymerase III, delta subunit; Region: holA; TIGR01128
695560002618	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
695560002619	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
695560002620	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
695560002621	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
695560002622	16S/18S rRNA binding site [nucleotide binding]; other site
695560002623	S13e-L30e interaction site [polypeptide binding]; other site
695560002624	25S rRNA binding site [nucleotide binding]; other site
695560002625	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
695560002626	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
695560002627	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
695560002628	elongation factor Tu; Reviewed; Region: PRK00049
695560002629	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
695560002630	G1 box; other site
695560002631	GEF interaction site [polypeptide binding]; other site
695560002632	GTP/Mg2+ binding site [chemical binding]; other site
695560002633	Switch I region; other site
695560002634	G2 box; other site
695560002635	G3 box; other site
695560002636	Switch II region; other site
695560002637	G4 box; other site
695560002638	G5 box; other site
695560002639	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
695560002640	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
695560002641	Antibiotic Binding Site [chemical binding]; other site
695560002642	trigger factor; Provisional; Region: tig; PRK01490
695560002643	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
695560002644	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
695560002645	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
695560002646	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
695560002647	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
695560002648	Walker A motif; other site
695560002649	ATP binding site [chemical binding]; other site
695560002650	Walker B motif; other site
695560002651	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
695560002652	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
695560002653	G1 box; other site
695560002654	GTP/Mg2+ binding site [chemical binding]; other site
695560002655	Switch I region; other site
695560002656	G2 box; other site
695560002657	G3 box; other site
695560002658	Switch II region; other site
695560002659	G4 box; other site
695560002660	G5 box; other site
695560002661	inner membrane transporter YjeM; Provisional; Region: PRK15238
695560002662	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
695560002663	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
695560002664	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
695560002665	aspartate kinase; Reviewed; Region: PRK09034
695560002666	AAK_AKiii-YclM-BS: Amino Acid Kinase Superfamily (AAK), AKiii-YclM-BS; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII, a monofunctional class enzyme found in...; Region: AAK_AKiii-YclM-BS; cd04245
695560002667	putative catalytic residues [active]
695560002668	putative nucleotide binding site [chemical binding]; other site
695560002669	putative aspartate binding site [chemical binding]; other site
695560002670	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
695560002671	ACT domains located C-terminal to the catalytic domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-YclM-BS_2; cd04916
695560002672	diaminopimelate decarboxylase; Region: lysA; TIGR01048
695560002673	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
695560002674	active site
695560002675	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
695560002676	substrate binding site [chemical binding]; other site
695560002677	catalytic residues [active]
695560002678	dimer interface [polypeptide binding]; other site
695560002679	Tetrahydrodipicolinate succinyltransferase N-terminal; Region: DapH_N; pfam08503
695560002680	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Region: DapD_Ac; TIGR03532
695560002681	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
695560002682	active site
695560002683	trimer interface [polypeptide binding]; other site
695560002684	substrate binding site [chemical binding]; other site
695560002685	CoA binding site [chemical binding]; other site
695560002686	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
695560002687	M20 Peptidase Aminoacyclase-1 YkuR-like proteins, including YkuR and Ama/HipO/HyuC proteins; Region: M20_Acy1_YkuR_like; cd05670
695560002688	metal binding site [ion binding]; metal-binding site
695560002689	putative dimer interface [polypeptide binding]; other site
695560002690	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
695560002691	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
695560002692	dimer interface [polypeptide binding]; other site
695560002693	active site
695560002694	catalytic residue [active]
695560002695	dihydrodipicolinate reductase; Provisional; Region: PRK00048
695560002696	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
695560002697	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
695560002698	aromatic amino acid aminotransferase; Validated; Region: PRK07309
695560002699	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
695560002700	pyridoxal 5'-phosphate binding site [chemical binding]; other site
695560002701	homodimer interface [polypeptide binding]; other site
695560002702	catalytic residue [active]
695560002703	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
695560002704	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
695560002705	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
695560002706	Beta-lactamase; Region: Beta-lactamase; pfam00144
695560002707	potential frameshift: common BLAST hit: gi|58336922|ref|YP_193507.1| multidrug resistance ABC transporter ATP binding protein
695560002708	potential frameshift: common BLAST hit: gi|58336922|ref|YP_193507.1| multidrug resistance ABC transporter ATP binding protein
695560002709	Transcriptional regulators [Transcription]; Region: MarR; COG1846
695560002710	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
695560002711	putative DNA binding site [nucleotide binding]; other site
695560002712	putative Zn2+ binding site [ion binding]; other site
695560002713	Protein of unknown function (DUF2974); Region: DUF2974; pfam11187
695560002714	Short repeat of unknown function (DUF308); Region: DUF308; pfam03729
695560002715	FMN-binding domain; Region: FMN_bind; cl01081
695560002716	nuc_hydro_ TvIAG:  Nucleoside hydrolases similar to the Inosine-adenosine-guanosine-preferring nucleoside hydrolase from Trypanosoma vivax.   Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base; Region: nuc_hydro_TvIAG; cd02647
695560002717	active site
695560002718	dimerization interface [polypeptide binding]; other site
695560002719	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
695560002720	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
695560002721	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
695560002722	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
695560002723	Integrase core domain; Region: rve; pfam00665
695560002724	Cupin domain; Region: Cupin_2; cl17218
695560002725	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
695560002726	Zn-dependent alcohol dehydrogenases, class III [Energy production and conversion]; Region: AdhC; COG1062
695560002727	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
695560002728	NAD(P) binding site [chemical binding]; other site
695560002729	DNA alkylation repair enzyme; Region: DNA_alkylation; pfam08713
695560002730	A new structural DNA glycosylase containing HEAT-like repeats; Region: AlkD_like_1; cd07064
695560002731	active site
695560002732	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
695560002733	beta-galactosidase; Region: BGL; TIGR03356
695560002734	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
695560002735	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
695560002736	DNA-binding site [nucleotide binding]; DNA binding site
695560002737	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
695560002738	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
695560002739	active site
695560002740	P-loop; other site
695560002741	phosphorylation site [posttranslational modification]
695560002742	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
695560002743	active site
695560002744	methionine cluster; other site
695560002745	phosphorylation site [posttranslational modification]
695560002746	metal binding site [ion binding]; metal-binding site
695560002747	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
695560002748	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
695560002749	potential frameshift: common BLAST hit: gi|161508229|ref|YP_001576727.1| transposase ORF_C
695560002750	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
695560002751	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
695560002752	Domain of unknown function (DUF3284); Region: DUF3284; pfam11687
695560002753	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
695560002754	beta-galactosidase; Region: BGL; TIGR03356
695560002755	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
695560002756	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
695560002757	DNA-binding site [nucleotide binding]; DNA binding site
695560002758	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
695560002759	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
695560002760	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
695560002761	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
695560002762	beta-galactosidase; Region: BGL; TIGR03356
695560002763	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
695560002764	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
695560002765	nucleotide binding site [chemical binding]; other site
695560002766	enolase; Provisional; Region: eno; PRK00077
695560002767	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
695560002768	dimer interface [polypeptide binding]; other site
695560002769	metal binding site [ion binding]; metal-binding site
695560002770	substrate binding pocket [chemical binding]; other site
695560002771	EDD domain protein, DegV family; Region: DegV; TIGR00762
695560002772	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
695560002773	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
695560002774	active site
695560002775	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
695560002776	Linear amide C-N hydrolases, choloylglycine hydrolase family; Region: CBAH; pfam02275
695560002777	Penicillin V acylase (PVA), also known as conjugated bile salt acid hydrolase (CBAH), catalyzes the hydrolysis of penicillin V to yield 6-amino penicillanic acid (6-APA), an important key intermediate of semisynthetic penicillins.  PVA has an N-terminal...; Region: Ntn_PVA; cd00542
695560002778	active site
695560002779	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
695560002780	thymidylate synthase; Region: thym_sym; TIGR03284
695560002781	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
695560002782	dimerization interface [polypeptide binding]; other site
695560002783	active site
695560002784	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
695560002785	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
695560002786	folate binding site [chemical binding]; other site
695560002787	NADP+ binding site [chemical binding]; other site
695560002788	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
695560002789	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
695560002790	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
695560002791	motif I; other site
695560002792	motif II; other site
695560002793	DNA/RNA non-specific endonuclease; Region: Endonuclea_NS_2; pfam13930
695560002794	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
695560002795	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
695560002796	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
695560002797	ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism]; Region: AbcC; COG1135
695560002798	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
695560002799	Walker A/P-loop; other site
695560002800	ATP binding site [chemical binding]; other site
695560002801	Q-loop/lid; other site
695560002802	ABC transporter signature motif; other site
695560002803	Walker B; other site
695560002804	D-loop; other site
695560002805	H-loop/switch region; other site
695560002806	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
695560002807	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
695560002808	dimer interface [polypeptide binding]; other site
695560002809	conserved gate region; other site
695560002810	ABC-ATPase subunit interface; other site
695560002811	fumarate hydratase; Reviewed; Region: fumC; PRK00485
695560002812	Class II fumarases; Region: Fumarase_classII; cd01362
695560002813	active site
695560002814	tetramer interface [polypeptide binding]; other site
695560002815	L-aspartate oxidase; Provisional; Region: PRK06175
695560002816	flavocytochrome c; Region: flavo_cyto_c; TIGR01813
695560002817	Predicted oxidoreductase [General function prediction only]; Region: COG3573
695560002818	L-lactate dehydrogenase; Reviewed; Region: ldh; PRK00066
695560002819	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
695560002820	tetramer (dimer of dimers) interface [polypeptide binding]; other site
695560002821	NAD binding site [chemical binding]; other site
695560002822	dimer interface [polypeptide binding]; other site
695560002823	substrate binding site [chemical binding]; other site
695560002824	Peptidase C1B subfamily (MEROPS database nomenclature); composed of eukaryotic bleomycin hydrolases (BH) and bacterial aminopeptidases C (pepC). The proteins of this subfamily contain a large insert relative to the C1A peptidase (papain) subfamily. BH is...; Region: Peptidase_C1B; cd00585
695560002825	trimer interface [polypeptide binding]; other site
695560002826	active site
695560002827	G bulge; other site
695560002828	potential frameshift: common BLAST hit: gi|161507403|ref|YP_001577357.1| 2-oxoglutarate-malate translocator
695560002829	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
695560002830	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
695560002831	active site
695560002832	HIGH motif; other site
695560002833	nucleotide binding site [chemical binding]; other site
695560002834	choice-of-anchor A domain; Region: choice_anch_A; TIGR04215
695560002835	Protein of unknown function (DUF441); Region: DUF441; pfam04284
695560002836	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
695560002837	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
695560002838	Probable transposase; Region: OrfB_IS605; pfam01385
695560002839	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
695560002840	Protein of unknown function (DUF441); Region: DUF441; cl01041
695560002841	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
695560002842	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
695560002843	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
695560002844	Walker A/P-loop; other site
695560002845	ATP binding site [chemical binding]; other site
695560002846	Q-loop/lid; other site
695560002847	ABC transporter signature motif; other site
695560002848	Walker B; other site
695560002849	D-loop; other site
695560002850	H-loop/switch region; other site
695560002851	ATP-binding cassette cobalt transporter; Region: DUF3744; pfam12558
695560002852	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
695560002853	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
695560002854	Walker A/P-loop; other site
695560002855	ATP binding site [chemical binding]; other site
695560002856	Q-loop/lid; other site
695560002857	ABC transporter signature motif; other site
695560002858	Walker B; other site
695560002859	D-loop; other site
695560002860	H-loop/switch region; other site
695560002861	hypothetical protein; Provisional; Region: PRK13661
695560002862	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
695560002863	ApbE family; Region: ApbE; pfam02424
695560002864	Domain of unknown function DUF1828; Region: DUF1828; pfam08861
695560002865	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
695560002866	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
695560002867	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
695560002868	Protein of unknown function (DUF3815); Region: DUF3815; cl01118
695560002869	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
695560002870	putative deacylase active site [active]
695560002871	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
695560002872	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
695560002873	S-adenosylmethionine binding site [chemical binding]; other site
695560002874	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
695560002875	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
695560002876	Zn2+ binding site [ion binding]; other site
695560002877	Mg2+ binding site [ion binding]; other site
695560002878	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
695560002879	synthetase active site [active]
695560002880	NTP binding site [chemical binding]; other site
695560002881	metal binding site [ion binding]; metal-binding site
695560002882	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
695560002883	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
695560002884	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
695560002885	putative active site [active]
695560002886	dimerization interface [polypeptide binding]; other site
695560002887	putative tRNAtyr binding site [nucleotide binding]; other site
695560002888	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
695560002889	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
695560002890	dimer interface [polypeptide binding]; other site
695560002891	motif 1; other site
695560002892	active site
695560002893	motif 2; other site
695560002894	motif 3; other site
695560002895	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
695560002896	anticodon binding site; other site
695560002897	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
695560002898	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
695560002899	dimer interface [polypeptide binding]; other site
695560002900	anticodon binding site; other site
695560002901	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
695560002902	homodimer interface [polypeptide binding]; other site
695560002903	motif 1; other site
695560002904	active site
695560002905	motif 2; other site
695560002906	GAD domain; Region: GAD; pfam02938
695560002907	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
695560002908	active site
695560002909	motif 3; other site
695560002910	aromatic amino acid aminotransferase; Validated; Region: PRK07309
695560002911	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
695560002912	pyridoxal 5'-phosphate binding site [chemical binding]; other site
695560002913	homodimer interface [polypeptide binding]; other site
695560002914	catalytic residue [active]
695560002915	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
695560002916	Flavoprotein; Region: Flavoprotein; pfam02441
695560002917	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
695560002918	potential frameshift: common BLAST hit: gi|295692853|ref|YP_003601463.1| Oxidoreductase, aldo/keto reductase family protein
695560002919	potential frameshift: common BLAST hit: gi|295692853|ref|YP_003601463.1| Oxidoreductase, aldo/keto reductase family protein
695560002920	sugar phosphate phosphatase; Provisional; Region: PRK10513
695560002921	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
695560002922	active site
695560002923	motif I; other site
695560002924	motif II; other site
695560002925	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
695560002926	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
695560002927	Putative D-isomer specific 2-hydroxyacid dehydrogenases, NAD-binding and catalytic domains; Region: 2-Hacid_dh_13; cd12178
695560002928	putative ligand binding site [chemical binding]; other site
695560002929	putative NAD binding site [chemical binding]; other site
695560002930	catalytic site [active]
695560002931	amino acid transporter; Region: 2A0306; TIGR00909
695560002932	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
695560002933	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
695560002934	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
695560002935	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
695560002936	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
695560002937	GIY-YIG motif/motif A; other site
695560002938	active site
695560002939	catalytic site [active]
695560002940	putative DNA binding site [nucleotide binding]; other site
695560002941	metal binding site [ion binding]; metal-binding site
695560002942	UvrB/uvrC motif; Region: UVR; pfam02151
695560002943	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
695560002944	H3TH domains of structure-specific 5' nucleases (or flap endonuclease-1-like) involved in DNA replication, repair, and recombination; Region: H3TH_StructSpec-5'-nucleases; cl14815
695560002945	DNA binding site [nucleotide binding]
695560002946	GTPase CgtA; Reviewed; Region: obgE; PRK12297
695560002947	GTP1/OBG; Region: GTP1_OBG; pfam01018
695560002948	Obg GTPase; Region: Obg; cd01898
695560002949	G1 box; other site
695560002950	GTP/Mg2+ binding site [chemical binding]; other site
695560002951	Switch I region; other site
695560002952	G2 box; other site
695560002953	G3 box; other site
695560002954	Switch II region; other site
695560002955	G4 box; other site
695560002956	G5 box; other site
695560002957	Domain of unknown function (DUF1967); Region: DUF1967; pfam09269
695560002958	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
695560002959	yrhL-like subfamily of SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_yrhL_like; cd01840
695560002960	catalytic triad [active]
695560002961	catalytic triad [active]
695560002962	oxyanion hole [active]
695560002963	ribonuclease Z; Region: RNase_Z; TIGR02651
695560002964	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
695560002965	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
695560002966	NAD(P) binding site [chemical binding]; other site
695560002967	active site
695560002968	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
695560002969	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
695560002970	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
695560002971	active site
695560002972	metal binding site [ion binding]; metal-binding site
695560002973	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
695560002974	Protein of unknown function (DUF2929); Region: DUF2929; pfam11151
695560002975	DNA polymerase III, alpha subunit [DNA replication, recombination, and repair]; Region: DnaE; COG0587
695560002976	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III; Region: PHP_PolIIIA; cd07431
695560002977	active site
695560002978	PHP Thumb interface [polypeptide binding]; other site
695560002979	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
695560002980	generic binding surface I; other site
695560002981	generic binding surface II; other site
695560002982	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
695560002983	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
695560002984	active site
695560002985	ADP/pyrophosphate binding site [chemical binding]; other site
695560002986	dimerization interface [polypeptide binding]; other site
695560002987	allosteric effector site; other site
695560002988	fructose-1,6-bisphosphate binding site; other site
695560002989	pyruvate kinase; Provisional; Region: PRK06354
695560002990	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
695560002991	domain interfaces; other site
695560002992	active site
695560002993	Phosphohistidine swiveling domain [Signal transduction mechanisms]; Region: COG3848
695560002994	Predicted RNA-bindining protein (contains S1 and HTH domains) [General function prediction only]; Region: COG2996
695560002995	S1 domain; Region: S1_2; pfam13509
695560002996	MarR family; Region: MarR_2; pfam12802
695560002997	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
695560002998	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
695560002999	active site
695560003000	Int/Topo IB signature motif; other site
695560003001	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
695560003002	segregation and condensation protein A; Reviewed; Region: scpA; PRK00104
695560003003	segregation and condensation protein B; Reviewed; Region: scpB; PRK00135
695560003004	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
695560003005	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
695560003006	RNA binding surface [nucleotide binding]; other site
695560003007	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
695560003008	active site
695560003009	Predicted membrane protein [Function unknown]; Region: COG3601
695560003010	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
695560003011	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
695560003012	cytidylate kinase; Provisional; Region: cmk; PRK00023
695560003013	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
695560003014	CMP-binding site; other site
695560003015	The sites determining sugar specificity; other site
695560003016	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06676
695560003017	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
695560003018	RNA binding site [nucleotide binding]; other site
695560003019	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
695560003020	RNA binding site [nucleotide binding]; other site
695560003021	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
695560003022	RNA binding site [nucleotide binding]; other site
695560003023	S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692
695560003024	RNA binding site [nucleotide binding]; other site
695560003025	GTP-binding protein Der; Reviewed; Region: PRK00093
695560003026	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
695560003027	G1 box; other site
695560003028	GTP/Mg2+ binding site [chemical binding]; other site
695560003029	Switch I region; other site
695560003030	G2 box; other site
695560003031	Switch II region; other site
695560003032	G3 box; other site
695560003033	G4 box; other site
695560003034	G5 box; other site
695560003035	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
695560003036	G1 box; other site
695560003037	GTP/Mg2+ binding site [chemical binding]; other site
695560003038	Switch I region; other site
695560003039	G2 box; other site
695560003040	G3 box; other site
695560003041	Switch II region; other site
695560003042	G4 box; other site
695560003043	G5 box; other site
695560003044	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
695560003045	IHF dimer interface [polypeptide binding]; other site
695560003046	IHF - DNA interface [nucleotide binding]; other site
695560003047	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
695560003048	TPR motif; other site
695560003049	binding surface
695560003050	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
695560003051	binding surface
695560003052	TPR motif; other site
695560003053	Uncharacterized conserved protein [Function unknown]; Region: COG1284
695560003054	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
695560003055	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
695560003056	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
695560003057	tRNA CCA-pyrophosphorylase; Provisional; Region: PRK13299
695560003058	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
695560003059	active site
695560003060	NTP binding site [chemical binding]; other site
695560003061	metal binding triad [ion binding]; metal-binding site
695560003062	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
695560003063	tRNA nucleotidyltransferase domain 2 putative; Region: tRNA_NucTran2_2; pfam13735
695560003064	Predicted membrane protein, hemolysin III homolog [General function prediction only]; Region: COG1272
695560003065	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
695560003066	EDD domain protein, DegV family; Region: DegV; TIGR00762
695560003067	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
695560003068	hypothetical protein; Provisional; Region: PRK13672
695560003069	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
695560003070	ribosome biogenesis GTP-binding protein YlqF; Region: GTPase_YlqF; TIGR03596
695560003071	Circularly permuted YlqF GTPase; Region: YlqF; cd01856
695560003072	GTP/Mg2+ binding site [chemical binding]; other site
695560003073	G4 box; other site
695560003074	G5 box; other site
695560003075	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
695560003076	G1 box; other site
695560003077	G1 box; other site
695560003078	GTP/Mg2+ binding site [chemical binding]; other site
695560003079	Switch I region; other site
695560003080	G2 box; other site
695560003081	G2 box; other site
695560003082	G3 box; other site
695560003083	G3 box; other site
695560003084	Switch II region; other site
695560003085	Switch II region; other site
695560003086	G4 box; other site
695560003087	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
695560003088	RNA/DNA hybrid binding site [nucleotide binding]; other site
695560003089	active site
695560003090	DNA protecting protein DprA; Region: dprA; TIGR00732
695560003091	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
695560003092	DNA topoisomerase I; Validated; Region: PRK05582
695560003093	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
695560003094	active site
695560003095	interdomain interaction site; other site
695560003096	putative metal-binding site [ion binding]; other site
695560003097	nucleotide binding site [chemical binding]; other site
695560003098	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
695560003099	domain I; other site
695560003100	DNA binding groove [nucleotide binding]
695560003101	phosphate binding site [ion binding]; other site
695560003102	domain II; other site
695560003103	domain III; other site
695560003104	nucleotide binding site [chemical binding]; other site
695560003105	catalytic site [active]
695560003106	domain IV; other site
695560003107	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
695560003108	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
695560003109	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
695560003110	Glucose inhibited division protein A; Region: GIDA; pfam01134
695560003111	potential frameshift: common BLAST hit: gi|58337280|ref|YP_193865.1| integrase-recombinase
695560003112	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
695560003113	active site
695560003114	HslU subunit interaction site [polypeptide binding]; other site
695560003115	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
695560003116	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
695560003117	Walker A motif; other site
695560003118	ATP binding site [chemical binding]; other site
695560003119	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
695560003120	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
695560003121	Aldose 1-epimerase, similar to Lactococcus lactis lacX; Region: Aldose_epim_lacX; cd09024
695560003122	active site
695560003123	catalytic residues [active]
695560003124	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
695560003125	Alpha/beta hydrolase of unknown function (DUF915); Region: DUF915; pfam06028
695560003126	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
695560003127	Integral membrane protein possibly involved in chromosome condensation [Cell division and chromosome partitioning]; Region: CrcB; COG0239
695560003128	camphor resistance protein CrcB; Provisional; Region: PRK14220
695560003129	dipeptidase PepV; Reviewed; Region: PRK07318
695560003130	M20 Peptidase Xaa-His dipeptidase (PepV) degrades hydrophobic dipeptides; Region: M20_PepV; cd03888
695560003131	active site
695560003132	metal binding site [ion binding]; metal-binding site
695560003133	Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381
695560003134	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
695560003135	Helix-turn-helix domain; Region: HTH_28; pfam13518
695560003136	putative transposase OrfB; Reviewed; Region: PHA02517
695560003137	HTH-like domain; Region: HTH_21; pfam13276
695560003138	Integrase core domain; Region: rve; pfam00665
695560003139	Integrase core domain; Region: rve_2; pfam13333
695560003140	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
695560003141	Probable transposase; Region: OrfB_IS605; pfam01385
695560003142	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
695560003143	Amino acid permease; Region: AA_permease_2; pfam13520
695560003144	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
695560003145	putative ornithine decarboxylase; Region: lacto_ODC_hypo; TIGR04318
695560003146	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
695560003147	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
695560003148	catalytic residue [active]
695560003149	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
695560003150	Aluminium resistance protein; Region: Alum_res; pfam06838
695560003151	Cystathionine beta-lyase family protein involved in aluminum resistance [Inorganic ion transport and metabolism]; Region: COG4100
695560003152	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
695560003153	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
695560003154	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
695560003155	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
695560003156	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
695560003157	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
695560003158	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
695560003159	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
695560003160	TrkA-N domain; Region: TrkA_N; pfam02254
695560003161	TrkA-C domain; Region: TrkA_C; pfam02080
695560003162	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
695560003163	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
695560003164	Superfamily II DNA helicase [DNA replication, recombination, and repair]; Region: RecQ; COG0514
695560003165	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
695560003166	ATP binding site [chemical binding]; other site
695560003167	putative Mg++ binding site [ion binding]; other site
695560003168	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
695560003169	nucleotide binding region [chemical binding]; other site
695560003170	ATP-binding site [chemical binding]; other site
695560003171	RQC domain; Region: RQC; pfam09382
695560003172	HRDC domain; Region: HRDC; pfam00570
695560003173	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
695560003174	homocysteine methyltransferase; Provisional; Region: mmuM; PRK09485
695560003175	Homocysteine S-methyltransferase; Region: S-methyl_trans; pfam02574
695560003176	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
695560003177	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
695560003178	active site
695560003179	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
695560003180	Beta-lactamase; Region: Beta-lactamase; pfam00144
695560003181	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
695560003182	pyridoxal binding site [chemical binding]; other site
695560003183	dimer interface [polypeptide binding]; other site
695560003184	ATP binding site [chemical binding]; other site
695560003185	ECF-type riboflavin transporter, S component; Region: ECF-ribofla_trS; cl17272
695560003186	Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229
695560003187	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
695560003188	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
695560003189	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
695560003190	inner membrane transporter YjeM; Provisional; Region: PRK15238
695560003191	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
695560003192	Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which...; Region: ZnMc; cl00064
695560003193	active site
695560003194	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
695560003195	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
695560003196	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
695560003197	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
695560003198	putative acyl-acceptor binding pocket; other site
695560003199	YSIRK type signal peptide; Region: YSIRK_signal; pfam04650
695560003200	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
695560003201	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
695560003202	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
695560003203	Nitroreductase-like family 1. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_1; cd02137
695560003204	dimer interface [polypeptide binding]; other site
695560003205	FMN binding site [chemical binding]; other site
695560003206	AAA domain; Region: AAA_33; pfam13671
695560003207	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
695560003208	Walker A/P-loop; other site
695560003209	ATP binding site [chemical binding]; other site
695560003210	Q-loop/lid; other site
695560003211	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
695560003212	Interdomain contacts; other site
695560003213	Cytokine receptor motif; other site
695560003214	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
695560003215	Neutral/alkaline non-lysosomal ceramidase; Region: Ceramidase_alk; cl04712
695560003216	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
695560003217	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
695560003218	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
695560003219	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
695560003220	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
695560003221	putative active site [active]
695560003222	potential frameshift: common BLAST hit: gi|268319516|ref|YP_003293172.1| type I restriction-modification system restriction subunit
695560003223	HsdM N-terminal domain; Region: HsdM_N; pfam12161
695560003224	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
695560003225	Methyltransferase domain; Region: Methyltransf_26; pfam13659
695560003226	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
695560003227	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
695560003228	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
695560003229	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
695560003230	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
695560003231	Int/Topo IB signature motif; other site
695560003232	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
695560003233	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
695560003234	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
695560003235	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
695560003236	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
695560003237	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
695560003238	ATP binding site [chemical binding]; other site
695560003239	putative Mg++ binding site [ion binding]; other site
695560003240	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
695560003241	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
695560003242	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
695560003243	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
695560003244	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
695560003245	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
695560003246	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
695560003247	Protein of unknown function DUF262; Region: DUF262; pfam03235
695560003248	Uncharacterized conserved protein [Function unknown]; Region: COG1479
695560003249	Uncharacterized conserved protein [Function unknown]; Region: COG3472
695560003250	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
695560003251	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
695560003252	metal binding site [ion binding]; metal-binding site
695560003253	dimer interface [polypeptide binding]; other site
695560003254	Peptidase_C39 like family; Region: Peptidase_C39_2; pfam13529
695560003255	putative active site [active]
695560003256	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
695560003257	NlpC/P60 family; Region: NLPC_P60; cl17555
695560003258	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
695560003259	substrate binding site [chemical binding]; other site
695560003260	THF binding site; other site
695560003261	zinc-binding site [ion binding]; other site
695560003262	S-ribosylhomocysteinase; Provisional; Region: PRK02260
695560003263	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
695560003264	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
695560003265	active site
695560003266	motif I; other site
695560003267	motif II; other site
695560003268	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
695560003269	benzoate transport; Region: 2A0115; TIGR00895
695560003270	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
695560003271	putative substrate translocation pore; other site
695560003272	Predicted membrane protein [Function unknown]; Region: COG1288
695560003273	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
695560003274	Int/Topo IB signature motif; other site
695560003275	Domain of unknown function (DUF955); Region: DUF955; pfam06114
695560003276	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
695560003277	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
695560003278	non-specific DNA binding site [nucleotide binding]; other site
695560003279	salt bridge; other site
695560003280	sequence-specific DNA binding site [nucleotide binding]; other site
695560003281	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
695560003282	AntA/AntB antirepressor; Region: AntA; cl01430
695560003283	Phage antirepressor protein KilAC domain; Region: ANT; pfam03374
695560003284	Helix-turn-helix domain; Region: HTH_17; pfam12728
695560003285	Protein of unknown function (DUF1071); Region: DUF1071; pfam06378
695560003286	Helix-turn-helix domain; Region: HTH_36; pfam13730
695560003287	VRR-NUC domain; Region: VRR_NUC; pfam08774
695560003288	phage transcriptional regulator, ArpU family; Region: phage_arpU; TIGR01637
695560003289	Terminase small subunit; Region: Terminase_2; pfam03592
695560003290	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5410
695560003291	Terminase-like family; Region: Terminase_6; pfam03237
695560003292	Phage-related terminase [General function prediction only]; Region: COG5362; cl02216
695560003293	phage-related protein, HI1409 family; Region: phge_rel_HI1409; TIGR01555
695560003294	Protein of unknown function (DUF1073); Region: DUF1073; pfam06381
695560003295	Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072
695560003296	NUMOD4 motif; Region: NUMOD4; pfam07463
695560003297	HNH endonuclease; Region: HNH_3; pfam13392
695560003298	GIYX(10-11)YIG family of class I homing endonucleases C-terminus (GIY-YIG_Cterm). Homing endonucleases promote the mobility of intron or intein by recognizing and cleaving a homologous allele that lacks the sequence. They catalyze a double-strand break...; Region: GIY-YIG_Cterm; cl11508
695560003299	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
695560003300	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3566
695560003301	Uncharacterized protein conserved in bacteria (DUF2213); Region: DUF2213; pfam09979
695560003302	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4834
695560003303	Uncharacterized protein conserved in bacteria (DUF2184); Region: DUF2184; pfam09950
695560003304	Protein of unknown function (DUF4054); Region: DUF4054; pfam13262
695560003305	Protein of unknown function (DUF3383); Region: DUF3383; pfam11863
695560003306	Protein of unknown function (DUF3277); Region: DUF3277; pfam11681
695560003307	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
695560003308	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
695560003309	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
695560003310	NlpC/P60 family; Region: NLPC_P60; cl17555
695560003311	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
695560003312	Uncharacterized homolog of phage Mu protein gp47 [Function unknown]; Region: XkdT; COG3299
695560003313	Protein of unknown function (DUF2612); Region: DUF2612; pfam11041
695560003314	SH3 domain protein; Region: SH3_and_anchor; TIGR04211
695560003315	Endo-N-acetylmuramidases (muramidases) are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues; Region: GH25_muramidase; cl10448
695560003316	active site
695560003317	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
695560003318	Uncharacterized conserved protein [Function unknown]; Region: COG1359
695560003319	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
695560003320	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
695560003321	Coenzyme A binding pocket [chemical binding]; other site
695560003322	Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Energy production and conversion]; Region: Tas; COG0667
695560003323	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
695560003324	active site
695560003325	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
695560003326	Replication initiator protein A (RepA) N-terminus; Region: RepA_N; pfam06970
695560003327	Exopolyphosphatase [Nucleotide transport and metabolism / Inorganic ion transport and metabolism]; Region: GppA; COG0248
695560003328	polyphosphate kinase; Provisional; Region: PRK05443
695560003329	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
695560003330	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
695560003331	Catalytic C-terminal domain, first repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C1_like; cd09165
695560003332	putative domain interface [polypeptide binding]; other site
695560003333	putative active site [active]
695560003334	catalytic site [active]
695560003335	Catalytic C-terminal domain, second repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C2_like; cd09168
695560003336	putative domain interface [polypeptide binding]; other site
695560003337	putative active site [active]
695560003338	catalytic site [active]
695560003339	Uncharacterized protein conserved in bacteria (DUF2252); Region: DUF2252; pfam10009
695560003340	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4320
695560003341	exopolyphosphatase; Region: exo_poly_only; TIGR03706
695560003342	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
695560003343	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
695560003344	NADH(P)-binding; Region: NAD_binding_10; pfam13460
695560003345	NAD(P) binding site [chemical binding]; other site
695560003346	active site
695560003347	potential frameshift: common BLAST hit: gi|58337318|ref|YP_193903.1| oxidoreductase
695560003348	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
695560003349	homopentamer interface [polypeptide binding]; other site
695560003350	active site
695560003351	Protein of unknown function (DUF1211); Region: DUF1211; cl01421
695560003352	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
695560003353	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
695560003354	dimerization interface [polypeptide binding]; other site
695560003355	DPS ferroxidase diiron center [ion binding]; other site
695560003356	ion pore; other site
695560003357	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
695560003358	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
695560003359	active site
695560003360	catalytic tetrad [active]
695560003361	putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834
695560003362	Abi-like protein; Region: Abi_2; cl01988
695560003363	Abi-like protein; Region: Abi_2; pfam07751
695560003364	multicopper oxidase; Provisional; Region: PRK10965
695560003365	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
695560003366	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
695560003367	RelB antitoxin; Region: RelB; cl01171
695560003368	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041; cl17396
695560003369	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
695560003370	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
695560003371	ABC transporter signature motif; other site
695560003372	Walker B; other site
695560003373	D-loop; other site
695560003374	H-loop/switch region; other site
695560003375	potential frameshift: common BLAST hit: gi|58337338|ref|YP_193923.1| glutamine ABC transporter substrate-binding protein
695560003376	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
695560003377	catalytic core [active]
695560003378	GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518
695560003379	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
695560003380	catalytic triad [active]
695560003381	NAD kinase [Coenzyme metabolism]; Region: nadF; cl01255
695560003382	Linear amide C-N hydrolases, choloylglycine hydrolase family; Region: CBAH; pfam02275
695560003383	Penicillin V acylase (PVA), also known as conjugated bile salt acid hydrolase (CBAH), catalyzes the hydrolysis of penicillin V to yield 6-amino penicillanic acid (6-APA), an important key intermediate of semisynthetic penicillins.  PVA has an N-terminal...; Region: Ntn_PVA; cd00542
695560003384	active site
695560003385	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
695560003386	MarR family; Region: MarR_2; pfam12802
695560003387	potential frameshift: common BLAST hit: gi|116630050|ref|YP_815222.1| major facilitator superfamily permease
695560003388	Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376
695560003389	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
695560003390	putative fructoselysine transporter; Provisional; Region: frlA; PRK11357
695560003391	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
695560003392	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
695560003393	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
695560003394	Walker A/P-loop; other site
695560003395	ATP binding site [chemical binding]; other site
695560003396	Q-loop/lid; other site
695560003397	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
695560003398	ABC transporter signature motif; other site
695560003399	Walker B; other site
695560003400	D-loop; other site
695560003401	H-loop/switch region; other site
695560003402	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
695560003403	AAA domain; Region: AAA_21; pfam13304
695560003404	Walker A/P-loop; other site
695560003405	ATP binding site [chemical binding]; other site
695560003406	Q-loop/lid; other site
695560003407	ABC transporter signature motif; other site
695560003408	Walker B; other site
695560003409	D-loop; other site
695560003410	H-loop/switch region; other site
695560003411	Branched-chain amino acid transport protein; Region: Branch_AA_trans; cl00547
695560003412	RNA:NAD 2'-phosphotransferase [Translation, ribosomal structure and biogenesis]; Region: KptA; COG1859
695560003413	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
695560003414	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
695560003415	NAD(P) binding site [chemical binding]; other site
695560003416	potential frameshift: common BLAST hit: gi|116495676|ref|YP_807410.1| saccharopine dehydrogenase related protein
695560003417	Amino acid permease; Region: AA_permease_2; pfam13520
695560003418	Alpha/beta hydrolase of unknown function (DUF915); Region: DUF915; pfam06028
695560003419	Pyrroline-5-carboxylate reductase [Amino acid transport and metabolism]; Region: ProC; COG0345
695560003420	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
695560003421	Protein of unknown function (DUF3800); Region: DUF3800; pfam12686
695560003422	recombination factor protein RarA; Reviewed; Region: PRK13342
695560003423	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
695560003424	Walker A motif; other site
695560003425	ATP binding site [chemical binding]; other site
695560003426	Walker B motif; other site
695560003427	arginine finger; other site
695560003428	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
695560003429	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
695560003430	endonuclease III; Region: ENDO3c; smart00478
695560003431	minor groove reading motif; other site
695560003432	helix-hairpin-helix signature motif; other site
695560003433	substrate binding pocket [chemical binding]; other site
695560003434	active site
695560003435	Predicted membrane protein [Function unknown]; Region: COG2855
695560003436	Bacterial SNF2 helicase associated; Region: SNF2_assoc; pfam08455
695560003437	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
695560003438	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
695560003439	ATP binding site [chemical binding]; other site
695560003440	putative Mg++ binding site [ion binding]; other site
695560003441	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
695560003442	nucleotide binding region [chemical binding]; other site
695560003443	ATP-binding site [chemical binding]; other site
695560003444	Glycerol-3-phosphate acyltransferase; Region: G3P_acyltransf; cl00410
695560003445	DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559
695560003446	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
695560003447	Mg2+ binding site [ion binding]; other site
695560003448	G-X-G motif; other site
695560003449	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
695560003450	anchoring element; other site
695560003451	dimer interface [polypeptide binding]; other site
695560003452	ATP binding site [chemical binding]; other site
695560003453	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
695560003454	active site
695560003455	putative metal-binding site [ion binding]; other site
695560003456	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
695560003457	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
695560003458	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
695560003459	CAP-like domain; other site
695560003460	active site
695560003461	primary dimer interface [polypeptide binding]; other site
695560003462	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
695560003463	Transcriptional regulator [Transcription]; Region: LysR; COG0583
695560003464	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
695560003465	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
695560003466	dimerization interface [polypeptide binding]; other site
695560003467	putative manganese-dependent inorganic pyrophosphatase; Provisional; Region: PRK05427
695560003468	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
695560003469	DHHA2 domain; Region: DHHA2; pfam02833
695560003470	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
695560003471	active site
695560003472	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
695560003473	non-specific DNA binding site [nucleotide binding]; other site
695560003474	salt bridge; other site
695560003475	sequence-specific DNA binding site [nucleotide binding]; other site
695560003476	potential frameshift: common BLAST hit: gi|161508078|ref|YP_001578045.1| transposase
695560003477	Protein of unknown function (DUF1275); Region: DUF1275; pfam06912
695560003478	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
695560003479	Helix-turn-helix domain; Region: HTH_38; pfam13936
695560003480	Integrase core domain; Region: rve; pfam00665
695560003481	Transglycosylase associated protein; Region: Transgly_assoc; cl00978
695560003482	SnoaL-like domain; Region: SnoaL_2; pfam12680
695560003483	Protein of unknown function (DUF2785); Region: DUF2785; pfam10978
695560003484	Aminoglycoside 3-N-acetyltransferase; Region: Antibiotic_NAT; cl01051
695560003485	Fic/DOC family; Region: Fic; pfam02661
695560003486	Fic/DOC family; Region: Fic; cl00960
695560003487	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
695560003488	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
695560003489	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
695560003490	Walker A/P-loop; other site
695560003491	ATP binding site [chemical binding]; other site
695560003492	Q-loop/lid; other site
695560003493	ABC transporter signature motif; other site
695560003494	Walker B; other site
695560003495	D-loop; other site
695560003496	H-loop/switch region; other site
695560003497	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
695560003498	Walker A/P-loop; other site
695560003499	ATP binding site [chemical binding]; other site
695560003500	ABC transporter; Region: ABC_tran; pfam00005
695560003501	Q-loop/lid; other site
695560003502	ABC transporter signature motif; other site
695560003503	Walker B; other site
695560003504	D-loop; other site
695560003505	H+ Antiporter protein; Region: 2A0121; TIGR00900
695560003506	LytTr DNA-binding domain; Region: LytTR; cl04498
695560003507	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
695560003508	Protein of unknown function (DUF3021); Region: DUF3021; pfam11457
695560003509	potential frameshift: common BLAST hit: gi|295693382|ref|YP_003601992.1| ABC transporter, ATP-binding protein
695560003510	Alpha/beta hydrolase of unknown function (DUF915); Region: DUF915; pfam06028
695560003511	Cpl-1 lysin (also known as Cpl-9 lysozyme / muramidase) is a bacterial cell wall endolysin encoded by the pneumococcal bacteriophage Cp-1, which cleaves the glycosidic N-acetylmuramoyl-(beta1,4)-N-acetylglucosamine bonds of the pneumococcal glycan chain; Region: GH25_Cpl1-like; cd06415
695560003512	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
695560003513	active site
695560003514	Bacterial surface layer protein; Region: SLAP; pfam03217
695560003515	site-specific tyrosine recombinase XerS; Reviewed; Region: xerS; PRK05084
695560003516	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
695560003517	active site
695560003518	DNA binding site [nucleotide binding]
695560003519	Int/Topo IB signature motif; other site
695560003520	EDD domain protein, DegV family; Region: DegV; TIGR00762
695560003521	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
695560003522	Transcriptional regulators [Transcription]; Region: MarR; COG1846
695560003523	MarR family; Region: MarR_2; pfam12802
695560003524	Fibronectin-binding protein A N-terminus (FbpA); Region: FbpA; pfam05833
695560003525	Domain of unknown function (DUF814); Region: DUF814; pfam05670
695560003526	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK12815
695560003527	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
695560003528	ATP-grasp domain; Region: ATP-grasp_4; cl17255
695560003529	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
695560003530	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
695560003531	ATP-grasp domain; Region: ATP-grasp_4; cl17255
695560003532	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
695560003533	IMP binding site; other site
695560003534	dimer interface [polypeptide binding]; other site
695560003535	interdomain contacts; other site
695560003536	partial ornithine binding site; other site
695560003537	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12838
695560003538	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
695560003539	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
695560003540	catalytic site [active]
695560003541	subunit interface [polypeptide binding]; other site
695560003542	pseudouridine synthase, RluA family; Region: rluA_subfam; TIGR00005
695560003543	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
695560003544	RNA binding surface [nucleotide binding]; other site
695560003545	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
695560003546	active site
695560003547	lipoprotein signal peptidase; Provisional; Region: PRK14797
695560003548	lipoprotein signal peptidase; Provisional; Region: PRK14787
695560003549	formate--tetrahydrofolate ligase; Provisional; Region: PRK13505
695560003550	Formyltetrahydrofolate synthetase (FTHFS) catalyzes the ATP-dependent activation of formate ion via its addition to the N10 position of tetrahydrofolate. FTHFS is a highly expressed key enzyme in both the Wood-Ljungdahl pathway of autotrophic CO2...; Region: FTHFS; cd00477
695560003551	Potassium binding sites [ion binding]; other site
695560003552	Cesium cation binding sites [ion binding]; other site
695560003553	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
695560003554	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
695560003555	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
695560003556	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
695560003557	active site
695560003558	metal binding site [ion binding]; metal-binding site
695560003559	Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0116
695560003560	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
695560003561	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
695560003562	DivIVA protein; Region: DivIVA; pfam05103
695560003563	DivIVA domain; Region: DivI1A_domain; TIGR03544
695560003564	hypothetical protein; Provisional; Region: PRK13660
695560003565	Holliday junction-specific endonuclease; Reviewed; Region: recU; PRK02234
695560003566	Transglycosylase; Region: Transgly; pfam00912
695560003567	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
695560003568	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
695560003569	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
695560003570	endonuclease III; Region: ENDO3c; smart00478
695560003571	minor groove reading motif; other site
695560003572	helix-hairpin-helix signature motif; other site
695560003573	substrate binding pocket [chemical binding]; other site
695560003574	active site
695560003575	Helix-turn-helix domain; Region: HTH_36; pfam13730
695560003576	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
695560003577	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
695560003578	AsnRS_cyto_like_N: N-terminal, anticodon recognition domain of the type found in human and Saccharomyces cerevisiae cytoplasmic asparaginyl-tRNA synthetase (AsnRS), in Brugia malayai AsnRs and, in various putative bacterial AsnRSs.  This domain is a...; Region: AsnRS_cyto_like_N; cd04323
695560003579	putative dimer interface [polypeptide binding]; other site
695560003580	putative anticodon binding site; other site
695560003581	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
695560003582	homodimer interface [polypeptide binding]; other site
695560003583	motif 1; other site
695560003584	motif 2; other site
695560003585	active site
695560003586	motif 3; other site
695560003587	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5353
695560003588	DnaQ family exonuclease/DinG family helicase, putative; Region: dinG_rel; TIGR01407
695560003589	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
695560003590	active site
695560003591	catalytic site [active]
695560003592	substrate binding site [chemical binding]; other site
695560003593	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
695560003594	ATP binding site [chemical binding]; other site
695560003595	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
695560003596	helicase-exonuclease AddAB, AddA subunit, Firmicutes type; Region: addA_Gpos; TIGR02785
695560003597	Part of AAA domain; Region: AAA_19; pfam13245
695560003598	Family description; Region: UvrD_C_2; pfam13538
695560003599	potential frameshift: common BLAST hit: gi|161507625|ref|YP_001577579.1| ATP-dependent exonuclease subunit B
695560003600	mevalonate kinase; Region: mevalon_kin; TIGR00549
695560003601	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
695560003602	diphosphomevalonate decarboxylase; Region: PLN02407
695560003603	diphosphomevalonate decarboxylase; Region: mevDPdecarb; TIGR01240
695560003604	phosphomevalonate kinase, ERG8-type, Gram-positive branch; Region: Pmev_kin_Gr_pos; TIGR01220
695560003605	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
695560003606	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
695560003607	isopentenyl pyrophosphate isomerase; Provisional; Region: PRK05437
695560003608	Isopentenyl-diphosphate:dimethylallyl diphosphate isomerase type 2 (IDI-2) FMN-binding domain. Two types of IDIs have been characterized at present. The long known IDI-1 is only dependent on divalent metals for activity, whereas IDI-2 requires a metal; Region: IDI-2_FMN; cd02811
695560003609	homotetramer interface [polypeptide binding]; other site
695560003610	FMN binding site [chemical binding]; other site
695560003611	homodimer contacts [polypeptide binding]; other site
695560003612	putative active site [active]
695560003613	putative substrate binding site [chemical binding]; other site
695560003614	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
695560003615	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
695560003616	active site
695560003617	motif I; other site
695560003618	motif II; other site
695560003619	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
695560003620	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
695560003621	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
695560003622	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
695560003623	S-adenosylmethionine binding site [chemical binding]; other site
695560003624	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
695560003625	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
695560003626	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
695560003627	Catalytic site [active]
695560003628	potential frameshift: common BLAST hit: gi|161507635|ref|YP_001577589.1| recombination factor protein RarA
695560003629	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
695560003630	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
695560003631	Walker A/P-loop; other site
695560003632	ATP binding site [chemical binding]; other site
695560003633	Q-loop/lid; other site
695560003634	ABC transporter signature motif; other site
695560003635	Walker B; other site
695560003636	D-loop; other site
695560003637	H-loop/switch region; other site
695560003638	Predicted transcriptional regulators [Transcription]; Region: COG1725
695560003639	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
695560003640	DNA-binding site [nucleotide binding]; DNA binding site
695560003641	peptidase T; Region: peptidase-T; TIGR01882
695560003642	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
695560003643	metal binding site [ion binding]; metal-binding site
695560003644	dimer interface [polypeptide binding]; other site
695560003645	Uncharacterized conserved protein [Function unknown]; Region: COG0327
695560003646	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
695560003647	Predicted SAM-dependent methyltransferase [General function prediction only]; Region: COG2384
695560003648	Family of unknown function (DUF633); Region: DUF633; pfam04816
695560003649	MutT homolog-1 (MTH1) is a member of the Nudix hydrolase superfamily. MTH1, the mammalian counterpart of MutT, hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP and 2-hydroxy-ATP, to monophosphates, thereby preventing the...; Region: MTH1; cd03427
695560003650	putative active site [active]
695560003651	nucleotide binding site [chemical binding]; other site
695560003652	nudix motif; other site
695560003653	putative metal binding site [ion binding]; other site
695560003654	Peptidase family M23; Region: Peptidase_M23; pfam01551
695560003655	RNA polymerase sigma factor RpoD; Validated; Region: PRK09210
695560003656	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
695560003657	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
695560003658	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
695560003659	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
695560003660	DNA binding residues [nucleotide binding]
695560003661	DNA primase; Validated; Region: dnaG; PRK05667
695560003662	CHC2 zinc finger; Region: zf-CHC2; cl17510
695560003663	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
695560003664	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
695560003665	active site
695560003666	metal binding site [ion binding]; metal-binding site
695560003667	interdomain interaction site; other site
695560003668	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
695560003669	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
695560003670	DALR anticodon binding domain; Region: DALR_1; pfam05746
695560003671	glycyl-tRNA synthetase subunit alpha; Validated; Region: glyQ; PRK09348
695560003672	motif 1; other site
695560003673	dimer interface [polypeptide binding]; other site
695560003674	active site
695560003675	motif 2; other site
695560003676	motif 3; other site
695560003677	Recombination protein O N terminal; Region: RecO_N; pfam11967
695560003678	DNA repair protein RecO; Region: reco; TIGR00613
695560003679	Recombination protein O C terminal; Region: RecO_C; pfam02565
695560003680	GTPase Era; Reviewed; Region: era; PRK00089
695560003681	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
695560003682	G1 box; other site
695560003683	GTP/Mg2+ binding site [chemical binding]; other site
695560003684	Switch I region; other site
695560003685	G2 box; other site
695560003686	Switch II region; other site
695560003687	G3 box; other site
695560003688	G4 box; other site
695560003689	G5 box; other site
695560003690	metal-binding heat shock protein; Provisional; Region: PRK00016
695560003691	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
695560003692	PhoH-like protein; Region: PhoH; pfam02562
695560003693	Yqey-like protein; Region: YqeY; pfam09424
695560003694	potential frameshift: common BLAST hit: gi|42519070|ref|NP_965000.1| manganese transport protein MntH2
695560003695	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
695560003696	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
695560003697	Walker A/P-loop; other site
695560003698	ATP binding site [chemical binding]; other site
695560003699	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
695560003700	Kinase/pyrophosphorylase; Region: Kinase-PPPase; pfam03618
695560003701	Peptidase family M23; Region: Peptidase_M23; pfam01551
695560003702	Peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: MsrA; COG0225
695560003703	Uncharacterized conserved protein [Function unknown]; Region: COG1284
695560003704	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
695560003705	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
695560003706	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
695560003707	homoserine kinase; Provisional; Region: PRK01212
695560003708	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
695560003709	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
695560003710	potential frameshift: common BLAST hit: gi|58337494|ref|YP_194079.1| homoserine dehydrogenase Hdh
695560003711	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
695560003712	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
695560003713	pyridoxal 5'-phosphate binding site [chemical binding]; other site
695560003714	catalytic residue [active]
695560003715	potential frameshift: common BLAST hit: gi|295693096|ref|YP_003601706.1| Aspartokinase
695560003716	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
695560003717	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
695560003718	ligand binding site [chemical binding]; other site
695560003719	flexible hinge region; other site
695560003720	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
695560003721	putative switch regulator; other site
695560003722	non-specific DNA interactions [nucleotide binding]; other site
695560003723	DNA binding site [nucleotide binding]
695560003724	sequence specific DNA binding site [nucleotide binding]; other site
695560003725	putative cAMP binding site [chemical binding]; other site
695560003726	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
695560003727	metal-binding site [ion binding]
695560003728	heavy metal translocating P-type ATPase; Region: ATPase-IB_hvy; TIGR01525
695560003729	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
695560003730	Soluble P-type ATPase [General function prediction only]; Region: COG4087
695560003731	potential frameshift: common BLAST hit: gi|58337497|ref|YP_194082.1| pheromone-peptide binding protein
695560003732	MucBP domain; Region: MucBP; pfam06458
695560003733	pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK07251
695560003734	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
695560003735	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
695560003736	Branched-chain amino acid transport protein; Region: Branch_AA_trans; cl00547
695560003737	Antibiotic biosynthesis monooxygenase; Region: ABM; pfam03992
695560003738	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
695560003739	dimerization interface [polypeptide binding]; other site
695560003740	Predicted acetyltransferase involved in intracellular survival and related acetyltransferases [General function prediction only]; Region: Eis; COG4552
695560003741	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
695560003742	Coenzyme A binding pocket [chemical binding]; other site
695560003743	potential frameshift: common BLAST hit: gi|295693108|ref|YP_003601718.1| Apo-citrate lyase
695560003744	carbamate kinase; Reviewed; Region: PRK12686
695560003745	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
695560003746	putative substrate binding site [chemical binding]; other site
695560003747	nucleotide binding site [chemical binding]; other site
695560003748	nucleotide binding site [chemical binding]; other site
695560003749	homodimer interface [polypeptide binding]; other site
695560003750	ornithine carbamoyltransferase; Validated; Region: PRK02102
695560003751	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
695560003752	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
695560003753	arginine deiminase; Provisional; Region: PRK01388
695560003754	Transcriptional regulator [Transcription]; Region: LysR; COG0583
695560003755	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
695560003756	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
695560003757	dimerization interface [polypeptide binding]; other site
695560003758	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
695560003759	plasma-membrane proton-efflux P-type ATPase; Region: ATPase-IIIA_H; TIGR01647
695560003760	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
695560003761	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
695560003762	Bacterial surface layer protein; Region: SLAP; pfam03217
695560003763	cardiolipin synthase; Region: bac_cardiolipin; TIGR04265
695560003764	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
695560003765	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
695560003766	putative active site [active]
695560003767	catalytic site [active]
695560003768	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
695560003769	putative active site [active]
695560003770	catalytic site [active]
695560003771	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
695560003772	conserved cys residue [active]
695560003773	potential frameshift: common BLAST hit: gi|161507670|ref|YP_001577624.1| cysteine synthase
695560003774	potential frameshift: common BLAST hit: gi|295693119|ref|YP_003601729.1| Surface protein
695560003775	Transposase; Region: DEDD_Tnp_IS110; pfam01548
695560003776	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
695560003777	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
695560003778	Transposase; Region: DEDD_Tnp_IS110; pfam01548
695560003779	Gram-positive signal peptide, YSIRK family; Region: YSIRK_signal; TIGR01168
695560003780	Phage integrase, N-terminal SAM-like domain; Region: Phage_integr_N2; pfam13495
695560003781	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
695560003782	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
695560003783	active site
695560003784	DNA binding site [nucleotide binding]
695560003785	Int/Topo IB signature motif; other site
695560003786	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
695560003787	Transposase; Region: DDE_Tnp_ISL3; pfam01610
695560003788	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
695560003789	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
695560003790	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
695560003791	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
695560003792	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
695560003793	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
695560003794	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
695560003795	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
695560003796	active site
695560003797	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
695560003798	DHH family; Region: DHH; pfam01368
695560003799	DHHA1 domain; Region: DHHA1; pfam02272
695560003800	Single-strand DNA-specific exonuclease, C terminal domain; Region: ssDNA-exonuc_C; cl11538
695560003801	Sortase A (SrtA) or subfamily-1 sortases are cysteine transpeptidases found in gram-positive bacteria that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. They do so by catalyzing a transpeptidation reaction in which the...; Region: Sortase_A_1; cd06165
695560003802	active site
695560003803	catalytic site [active]
695560003804	GTP-binding protein LepA; Provisional; Region: PRK05433
695560003805	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
695560003806	G1 box; other site
695560003807	putative GEF interaction site [polypeptide binding]; other site
695560003808	GTP/Mg2+ binding site [chemical binding]; other site
695560003809	Switch I region; other site
695560003810	G2 box; other site
695560003811	G3 box; other site
695560003812	Switch II region; other site
695560003813	G4 box; other site
695560003814	G5 box; other site
695560003815	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
695560003816	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
695560003817	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
695560003818	chaperone protein DnaJ; Provisional; Region: PRK14276
695560003819	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
695560003820	HSP70 interaction site [polypeptide binding]; other site
695560003821	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
695560003822	substrate binding site [polypeptide binding]; other site
695560003823	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
695560003824	Zn binding sites [ion binding]; other site
695560003825	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
695560003826	dimer interface [polypeptide binding]; other site
695560003827	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
695560003828	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
695560003829	nucleotide binding site [chemical binding]; other site
695560003830	NEF interaction site [polypeptide binding]; other site
695560003831	SBD interface [polypeptide binding]; other site
695560003832	GrpE; Region: GrpE; pfam01025
695560003833	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
695560003834	dimer interface [polypeptide binding]; other site
695560003835	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
695560003836	heat-inducible transcription repressor; Provisional; Region: hrcA; PRK00082
695560003837	Winged helix-turn-helix transcription repressor, HrcA DNA-binding; Region: HrcA_DNA-bdg; pfam03444
695560003838	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
695560003839	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
695560003840	ABC transporter; Region: ABC_tran_2; pfam12848
695560003841	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
695560003842	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
695560003843	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
695560003844	active site
695560003845	Riboflavin kinase; Region: Flavokinase; pfam01687
695560003846	potential frameshift: common BLAST hit: gi|58337532|ref|YP_194117.1| tRNA pseudouridine synthase B
695560003847	Ribosome-binding factor A; Region: RBFA; cl00542
695560003848	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
695560003849	translation initiation factor IF-2; Validated; Region: infB; PRK05306
695560003850	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
695560003851	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
695560003852	G1 box; other site
695560003853	putative GEF interaction site [polypeptide binding]; other site
695560003854	GTP/Mg2+ binding site [chemical binding]; other site
695560003855	Switch I region; other site
695560003856	G2 box; other site
695560003857	G3 box; other site
695560003858	Switch II region; other site
695560003859	G4 box; other site
695560003860	G5 box; other site
695560003861	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
695560003862	Translation-initiation factor 2; Region: IF-2; pfam11987
695560003863	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
695560003864	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; Region: Ribosomal_L7Ae; cl00600
695560003865	Ylxr homologs; group of conserved hypothetical bacterial proteins of unknown function; structure revealed putative RNA binding cleft; proteins are encoded by an operon that includes other proteins involved in transcription and/or translation; Region: YlxR; cd00279
695560003866	putative RNA binding cleft [nucleotide binding]; other site
695560003867	transcription elongation factor NusA; Provisional; Region: nusA; PRK12327
695560003868	NusA N-terminal domain; Region: NusA_N; pfam08529
695560003869	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
695560003870	RNA binding site [nucleotide binding]; other site
695560003871	homodimer interface [polypeptide binding]; other site
695560003872	NusA-like KH domain; Region: KH_5; pfam13184
695560003873	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
695560003874	G-X-X-G motif; other site
695560003875	ribosome maturation protein RimP; Reviewed; Region: PRK00092
695560003876	Sm and related proteins; Region: Sm_like; cl00259
695560003877	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
695560003878	putative oligomer interface [polypeptide binding]; other site
695560003879	putative RNA binding site [nucleotide binding]; other site
695560003880	DNA polymerase III PolC; Validated; Region: polC; PRK00448
695560003881	DNA polymerase III polC-type N-terminus; Region: DNA_pol3_alph_N; pfam11490
695560003882	polC_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold nucleic acid binding domain of Bacillus subtilis type C replicative DNA polymerase III alpha subunit (polC). Replication in B. subtilis and Staphylococcus aureus requires two...; Region: polC_OBF; cd04484
695560003883	generic binding surface II; other site
695560003884	generic binding surface I; other site
695560003885	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
695560003886	active site
695560003887	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
695560003888	active site
695560003889	catalytic site [active]
695560003890	substrate binding site [chemical binding]; other site
695560003891	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III at PolC gene; Region: PHP_PolIIIA_POLC; cd07435
695560003892	prolyl-tRNA synthetase; Provisional; Region: PRK09194
695560003893	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
695560003894	dimer interface [polypeptide binding]; other site
695560003895	motif 1; other site
695560003896	active site
695560003897	motif 2; other site
695560003898	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
695560003899	putative deacylase active site [active]
695560003900	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
695560003901	active site
695560003902	motif 3; other site
695560003903	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
695560003904	anticodon binding site; other site
695560003905	RIP metalloprotease RseP; Region: TIGR00054
695560003906	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
695560003907	active site
695560003908	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
695560003909	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
695560003910	protein binding site [polypeptide binding]; other site
695560003911	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
695560003912	putative substrate binding region [chemical binding]; other site
695560003913	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
695560003914	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
695560003915	undecaprenyl pyrophosphate synthase; Provisional; Region: PRK14830
695560003916	Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255
695560003917	catalytic residue [active]
695560003918	putative FPP diphosphate  binding site; other site
695560003919	putative FPP binding hydrophobic cleft; other site
695560003920	dimer interface [polypeptide binding]; other site
695560003921	putative IPP diphosphate binding site; other site
695560003922	ribosome recycling factor; Reviewed; Region: frr; PRK00083
695560003923	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
695560003924	hinge region; other site
695560003925	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
695560003926	putative nucleotide binding site [chemical binding]; other site
695560003927	uridine monophosphate binding site [chemical binding]; other site
695560003928	homohexameric interface [polypeptide binding]; other site
695560003929	elongation factor Ts; Provisional; Region: tsf; PRK09377
695560003930	UBA/TS-N domain; Region: UBA; pfam00627
695560003931	Elongation factor TS; Region: EF_TS; pfam00889
695560003932	Elongation factor TS; Region: EF_TS; pfam00889
695560003933	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
695560003934	rRNA interaction site [nucleotide binding]; other site
695560003935	S8 interaction site; other site
695560003936	putative laminin-1 binding site; other site
695560003937	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
695560003938	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
695560003939	S-adenosylmethionine binding site [chemical binding]; other site
695560003940	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
695560003941	GIY-YIG motif/motif A; other site
695560003942	putative active site [active]
695560003943	putative metal binding site [ion binding]; other site
695560003944	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
695560003945	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
695560003946	putative acyl-acceptor binding pocket; other site
695560003947	Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane]; Region: Cfa; COG2230
695560003948	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
695560003949	S-adenosylmethionine binding site [chemical binding]; other site
695560003950	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
695560003951	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
695560003952	active site
695560003953	Zn binding site [ion binding]; other site
695560003954	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
695560003955	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
695560003956	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
695560003957	Walker A/P-loop; other site
695560003958	ATP binding site [chemical binding]; other site
695560003959	Q-loop/lid; other site
695560003960	ABC transporter signature motif; other site
695560003961	Walker B; other site
695560003962	D-loop; other site
695560003963	H-loop/switch region; other site
695560003964	potential frameshift: common BLAST hit: gi|58337553|ref|YP_194138.1| ABC transporter ATP binding and permease protein
695560003965	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3763
695560003966	Bacterial protein of unknown function (DUF896); Region: DUF896; pfam05979
695560003967	LexA repressor; Validated; Region: PRK00215
695560003968	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
695560003969	putative DNA binding site [nucleotide binding]; other site
695560003970	putative Zn2+ binding site [ion binding]; other site
695560003971	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
695560003972	Catalytic site [active]
695560003973	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
695560003974	active site
695560003975	catalytic triad [active]
695560003976	oxyanion hole [active]
695560003977	Family 4 Uracil-DNA glycosylase (UDG), found exclusively in thermophilic organisms; Region: UDG_F4_TTUDGA_like; cd10030
695560003978	active site
695560003979	Fe-S cluster binding site [ion binding]; other site
695560003980	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
695560003981	Bacterial low temperature requirement A protein (LtrA); Region: LtrA; cl01754
695560003982	Transposase IS200 like; Region: Y1_Tnp; pfam01797
695560003983	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
695560003984	Probable transposase; Region: OrfB_IS605; pfam01385
695560003985	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
695560003986	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
695560003987	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
695560003988	RimM N-terminal domain; Region: RimM; pfam01782
695560003989	PRC-barrel domain; Region: PRC; pfam05239
695560003990	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
695560003991	signal recognition particle protein; Provisional; Region: PRK10867
695560003992	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
695560003993	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
695560003994	P loop; other site
695560003995	GTP binding site [chemical binding]; other site
695560003996	Signal peptide binding domain; Region: SRP_SPB; pfam02978
695560003997	Putative helix-turn-helix protein, YlxM / p13 like; Region: UPF0122; pfam04297
695560003998	putative DNA-binding protein; Validated; Region: PRK00118
695560003999	Sugar transport protein; Region: Sugar_transport; pfam06800
695560004000	amino acid transporter; Region: 2A0306; TIGR00909
695560004001	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
695560004002	Peptidase family C69; Region: Peptidase_C69; pfam03577
695560004003	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
695560004004	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
695560004005	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
695560004006	P loop; other site
695560004007	GTP binding site [chemical binding]; other site
695560004008	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
695560004009	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
695560004010	Walker A/P-loop; other site
695560004011	ATP binding site [chemical binding]; other site
695560004012	Q-loop/lid; other site
695560004013	SMC proteins Flexible Hinge Domain; Region: SMC_hinge; smart00968
695560004014	Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly.  The complex contains two alpha and four beta subunits, the two subunits...; Region: Prefoldin; cl09111
695560004015	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
695560004016	ABC transporter signature motif; other site
695560004017	Walker B; other site
695560004018	D-loop; other site
695560004019	H-loop/switch region; other site
695560004020	ribonuclease III; Reviewed; Region: rnc; PRK00102
695560004021	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
695560004022	dimerization interface [polypeptide binding]; other site
695560004023	active site
695560004024	metal binding site [ion binding]; metal-binding site
695560004025	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
695560004026	The substrate binding component of an ABC-type lactococcal OppA-like transport system contains; Region: PBP2_Lactococcal_OppA_like; cd08510
695560004027	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
695560004028	peptide binding site [polypeptide binding]; other site
695560004029	The substrate binding component of an ABC-type lactococcal OppA-like transport system contains; Region: PBP2_Lactococcal_OppA_like; cd08510
695560004030	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
695560004031	peptide binding site [polypeptide binding]; other site
695560004032	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
695560004033	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
695560004034	dimer interface [polypeptide binding]; other site
695560004035	conserved gate region; other site
695560004036	putative PBP binding loops; other site
695560004037	ABC-ATPase subunit interface; other site
695560004038	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
695560004039	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
695560004040	dimer interface [polypeptide binding]; other site
695560004041	conserved gate region; other site
695560004042	putative PBP binding loops; other site
695560004043	ABC-ATPase subunit interface; other site
695560004044	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
695560004045	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
695560004046	Walker A/P-loop; other site
695560004047	ATP binding site [chemical binding]; other site
695560004048	Q-loop/lid; other site
695560004049	ABC transporter signature motif; other site
695560004050	Walker B; other site
695560004051	D-loop; other site
695560004052	H-loop/switch region; other site
695560004053	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
695560004054	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
695560004055	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
695560004056	Walker A/P-loop; other site
695560004057	ATP binding site [chemical binding]; other site
695560004058	Q-loop/lid; other site
695560004059	ABC transporter signature motif; other site
695560004060	Walker B; other site
695560004061	D-loop; other site
695560004062	H-loop/switch region; other site
695560004063	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
695560004064	acyl carrier protein; Provisional; Region: acpP; PRK00982
695560004065	putative phosphate acyltransferase; Provisional; Region: PRK05331
695560004066	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
695560004067	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
695560004068	ssDNA binding site; other site
695560004069	generic binding surface II; other site
695560004070	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
695560004071	ATP binding site [chemical binding]; other site
695560004072	putative Mg++ binding site [ion binding]; other site
695560004073	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
695560004074	nucleotide binding region [chemical binding]; other site
695560004075	ATP-binding site [chemical binding]; other site
695560004076	DAK2 domain fusion protein YloV; Region: YloV; TIGR03599
695560004077	DAK2 domain; Region: Dak2; pfam02734
695560004078	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1302
695560004079	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
695560004080	SOCS (suppressors of cytokine signaling) box. The SOCS box is found in the C-terminal region of CIS/SOCS family proteins (in combination with a SH2 domain), ASBs (ankyrin repeat-containing proteins with a SOCS box), SSBs (SPRY domain-containing proteins...; Region: SOCS; cl02533
695560004081	Thiamine pyrophosphokinase [Coenzyme metabolism]; Region: THI80; COG1564
695560004082	Thiamine pyrophosphokinase; Region: TPK; cd07995
695560004083	active site
695560004084	dimerization interface [polypeptide binding]; other site
695560004085	thiamine binding site [chemical binding]; other site
695560004086	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
695560004087	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
695560004088	substrate binding site [chemical binding]; other site
695560004089	hexamer interface [polypeptide binding]; other site
695560004090	metal binding site [ion binding]; metal-binding site
695560004091	GTPase RsgA; Reviewed; Region: PRK00098
695560004092	S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466
695560004093	RNA binding site [nucleotide binding]; other site
695560004094	homodimer interface [polypeptide binding]; other site
695560004095	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
695560004096	GTPase/Zn-binding domain interface [polypeptide binding]; other site
695560004097	GTP/Mg2+ binding site [chemical binding]; other site
695560004098	G4 box; other site
695560004099	G5 box; other site
695560004100	G1 box; other site
695560004101	Switch I region; other site
695560004102	G2 box; other site
695560004103	G3 box; other site
695560004104	Switch II region; other site
695560004105	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
695560004106	Catalytic domain of Protein Kinases; Region: PKc; cd00180
695560004107	active site
695560004108	ATP binding site [chemical binding]; other site
695560004109	substrate binding site [chemical binding]; other site
695560004110	activation loop (A-loop); other site
695560004111	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
695560004112	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2815
695560004113	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
695560004114	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
695560004115	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
695560004116	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
695560004117	active site
695560004118	16S rRNA methyltransferase B; Provisional; Region: PRK14902
695560004119	NusB family; Region: NusB; pfam01029
695560004120	putative RNA binding site [nucleotide binding]; other site
695560004121	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
695560004122	S-adenosylmethionine binding site [chemical binding]; other site
695560004123	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
695560004124	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
695560004125	putative active site [active]
695560004126	substrate binding site [chemical binding]; other site
695560004127	putative cosubstrate binding site; other site
695560004128	catalytic site [active]
695560004129	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
695560004130	substrate binding site [chemical binding]; other site
695560004131	Primosomal protein N' (replication factor Y) - superfamily II helicase [DNA replication, recombination, and repair]; Region: PriA; COG1198
695560004132	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
695560004133	ATP binding site [chemical binding]; other site
695560004134	putative Mg++ binding site [ion binding]; other site
695560004135	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
695560004136	nucleotide binding region [chemical binding]; other site
695560004137	ATP-binding site [chemical binding]; other site
695560004138	DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392
695560004139	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
695560004140	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
695560004141	catalytic site [active]
695560004142	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
695560004143	potential frameshift: common BLAST hit: gi|295693198|ref|YP_003601808.1| DNA repair protein RecN
695560004144	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
695560004145	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
695560004146	RNA binding surface [nucleotide binding]; other site
695560004147	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
695560004148	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
695560004149	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
695560004150	substrate binding pocket [chemical binding]; other site
695560004151	chain length determination region; other site
695560004152	substrate-Mg2+ binding site; other site
695560004153	catalytic residues [active]
695560004154	aspartate-rich region 1; other site
695560004155	active site lid residues [active]
695560004156	aspartate-rich region 2; other site
695560004157	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
695560004158	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
695560004159	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
695560004160	generic binding surface II; other site
695560004161	generic binding surface I; other site
695560004162	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14190
695560004163	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
695560004164	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
695560004165	homodimer interface [polypeptide binding]; other site
695560004166	NADP binding site [chemical binding]; other site
695560004167	substrate binding site [chemical binding]; other site
695560004168	transcription antitermination factor NusB; Region: nusB; TIGR01951
695560004169	putative RNA binding site [nucleotide binding]; other site
695560004170	Asp23 family; Region: Asp23; pfam03780
695560004171	elongation factor P; Validated; Region: PRK00529
695560004172	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
695560004173	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
695560004174	RNA binding site [nucleotide binding]; other site
695560004175	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
695560004176	RNA binding site [nucleotide binding]; other site
695560004177	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
695560004178	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
695560004179	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
695560004180	active site
695560004181	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
695560004182	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
695560004183	Uncharacterized protein conserved in bacteria (DUF2325); Region: DUF2325; pfam10087
695560004184	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
695560004185	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
695560004186	homodimer interface [polypeptide binding]; other site
695560004187	substrate-cofactor binding pocket; other site
695560004188	catalytic residue [active]
695560004189	4-oxalocrotonate tautomerase; Provisional; Region: PRK02220
695560004190	active site 1 [active]
695560004191	dimer interface [polypeptide binding]; other site
695560004192	hexamer interface [polypeptide binding]; other site
695560004193	active site 2 [active]
695560004194	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
695560004195	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
695560004196	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
695560004197	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
695560004198	Cpl-1 lysin (also known as Cpl-9 lysozyme / muramidase) is a bacterial cell wall endolysin encoded by the pneumococcal bacteriophage Cp-1, which cleaves the glycosidic N-acetylmuramoyl-(beta1,4)-N-acetylglucosamine bonds of the pneumococcal glycan chain; Region: GH25_Cpl1-like; cd06415
695560004199	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
695560004200	active site
695560004201	Bacterial surface layer protein; Region: SLAP; pfam03217
695560004202	Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX)...; Region: ArsC_like; cd03036
695560004203	ArsC family; Region: ArsC; pfam03960
695560004204	putative ArsC-like catalytic residues; other site
695560004205	putative TRX-like catalytic residues [active]
695560004206	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
695560004207	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
695560004208	substrate binding pocket [chemical binding]; other site
695560004209	Cpl-1 lysin (also known as Cpl-9 lysozyme / muramidase) is a bacterial cell wall endolysin encoded by the pneumococcal bacteriophage Cp-1, which cleaves the glycosidic N-acetylmuramoyl-(beta1,4)-N-acetylglucosamine bonds of the pneumococcal glycan chain; Region: GH25_Cpl1-like; cd06415
695560004210	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
695560004211	active site
695560004212	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
695560004213	Prophage endopeptidase tail; Region: Prophage_tail; cl12123
695560004214	Bacterial SH3 domain; Region: SH3_4; pfam06347
695560004215	Protein of unknown function (DUF1640); Region: DUF1640; pfam07798
695560004216	Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]; Region: COG1579
695560004217	tape measure domain; Region: tape_meas_nterm; TIGR02675
695560004218	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
695560004219	NlpC/P60 family; Region: NLPC_P60; cl17555
695560004220	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
695560004221	N-acetyl-D-glucosamine binding site [chemical binding]; other site
695560004222	catalytic residue [active]
695560004223	Bacteriophage Gp15 protein; Region: Phage_Gp15; pfam06854
695560004224	Minor capsid protein from bacteriophage; Region: Minor_capsid_3; pfam12691
695560004225	Minor capsid protein; Region: Minor_capsid_2; pfam11114
695560004226	Minor capsid protein; Region: Minor_capsid_1; pfam10665
695560004227	Phage minor structural protein GP20; Region: Phage_GP20; pfam06810
695560004228	Phage minor capsid protein 2; Region: Phage_min_cap2; pfam06152
695560004229	phage portal protein, putative, A118 family; Region: A118_put_portal; TIGR01542
695560004230	Phage portal protein, SPP1 Gp6-like; Region: Phage_prot_Gp6; pfam05133
695560004231	Phage terminase large subunit; Region: Terminase_3; cl12054
695560004232	Terminase-like family; Region: Terminase_6; pfam03237
695560004233	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
695560004234	ParB-like nuclease domain; Region: ParB; smart00470
695560004235	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
695560004236	Ligand Binding Site [chemical binding]; other site
695560004237	ASC-1 homology or ASCH domain, a small beta-barrel domain found in all three kingdoms of life. ASCH resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as an RNA-binding domain during coactivation; Region: ASCH; cl01020
695560004238	phage transcriptional regulator, ArpU family; Region: phage_arpU; TIGR01637
695560004239	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
695560004240	putative trifunctional 2-polyprenylphenol hydroxylase/glutamate synthase subunit beta/ferritin domain-containing protein; Provisional; Region: PRK12775
695560004241	DNA replication protein DnaC; Validated; Region: PRK07952
695560004242	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
695560004243	Walker A motif; other site
695560004244	ATP binding site [chemical binding]; other site
695560004245	Walker B motif; other site
695560004246	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
695560004247	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
695560004248	non-specific DNA binding site [nucleotide binding]; other site
695560004249	salt bridge; other site
695560004250	sequence-specific DNA binding site [nucleotide binding]; other site
695560004251	phage conserved hypothetical protein, C-terminal domain; Region: phg_TIGR02220
695560004252	Protein of unknown function (DUF1071); Region: DUF1071; pfam06378
695560004253	Domain of unknown function (DUF771); Region: DUF771; cl09962
695560004254	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
695560004255	ORF6C domain; Region: ORF6C; pfam10552
695560004256	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
695560004257	non-specific DNA binding site [nucleotide binding]; other site
695560004258	salt bridge; other site
695560004259	sequence-specific DNA binding site [nucleotide binding]; other site
695560004260	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
695560004261	sequence-specific DNA binding site [nucleotide binding]; other site
695560004262	salt bridge; other site
695560004263	Domain of unknown function (DUF955); Region: DUF955; pfam06114
695560004264	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
695560004265	Int/Topo IB signature motif; other site
695560004266	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydD; COG4988
695560004267	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
695560004268	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
695560004269	Walker A/P-loop; other site
695560004270	ATP binding site [chemical binding]; other site
695560004271	Q-loop/lid; other site
695560004272	ABC transporter signature motif; other site
695560004273	Walker B; other site
695560004274	D-loop; other site
695560004275	H-loop/switch region; other site
695560004276	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
695560004277	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
695560004278	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
695560004279	Walker A/P-loop; other site
695560004280	ATP binding site [chemical binding]; other site
695560004281	Q-loop/lid; other site
695560004282	ABC transporter signature motif; other site
695560004283	Walker B; other site
695560004284	D-loop; other site
695560004285	H-loop/switch region; other site
695560004286	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
695560004287	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
695560004288	active site
695560004289	motif I; other site
695560004290	motif II; other site
695560004291	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
695560004292	Short C-terminal domain; Region: SHOCT; pfam09851
695560004293	Uncharacterized protein conserved in bacteria (DUF2263); Region: DUF2263; pfam10021
695560004294	x-prolyl-dipeptidyl aminopeptidase; Provisional; Region: PRK05371
695560004295	X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal; Region: PepX_N; smart00940
695560004296	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; pfam08530
695560004297	methionine sulfoxide reductase B; Provisional; Region: PRK00222
695560004298	methionine sulfoxide reductase B; Provisional; Region: PRK05508
695560004299	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
695560004300	Probable transposase; Region: OrfB_IS605; pfam01385
695560004301	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
695560004302	Transposase IS200 like; Region: Y1_Tnp; pfam01797
695560004303	Sugar transport protein; Region: Sugar_transport; pfam06800
695560004304	YSIRK type signal peptide; Region: YSIRK_signal; pfam04650
695560004305	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
695560004306	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
695560004307	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
695560004308	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
695560004309	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
695560004310	ATP-grasp domain; Region: ATP-grasp_4; cl17255
695560004311	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
695560004312	IMP binding site; other site
695560004313	dimer interface [polypeptide binding]; other site
695560004314	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
695560004315	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; pfam00988
695560004316	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
695560004317	catalytic site [active]
695560004318	subunit interface [polypeptide binding]; other site
695560004319	dihydroorotase; Validated; Region: pyrC; PRK09357
695560004320	Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317
695560004321	active site
695560004322	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
695560004323	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
695560004324	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
695560004325	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
695560004326	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
695560004327	active site
695560004328	Dihydroorotate dehydrogenase (DHOD) class 1B FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine...; Region: DHOD_1B_like; cd04740
695560004329	dihydroorotate dehydrogenase (subfamily 1) family protein; Region: pyrD_sub1_fam; TIGR01037
695560004330	heterodimer interface [polypeptide binding]; other site
695560004331	active site
695560004332	FMN binding site [chemical binding]; other site
695560004333	homodimer interface [polypeptide binding]; other site
695560004334	substrate binding site [chemical binding]; other site
695560004335	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
695560004336	active site
695560004337	dimer interface [polypeptide binding]; other site
695560004338	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
695560004339	active site
695560004340	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
695560004341	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
695560004342	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
695560004343	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
695560004344	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
695560004345	motif II; other site
695560004346	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
695560004347	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
695560004348	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
695560004349	Cl- selectivity filter; other site
695560004350	Cl- binding residues [ion binding]; other site
695560004351	pore gating glutamate residue; other site
695560004352	dimer interface [polypeptide binding]; other site
695560004353	H+/Cl- coupling transport residue; other site
695560004354	Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which...; Region: ZnMc; cl00064
695560004355	Acetyltransferase (GNAT) domain; Region: Acetyltransf_8; pfam13523
695560004356	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
695560004357	Coenzyme A binding pocket [chemical binding]; other site
695560004358	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
695560004359	Serine dehydratase alpha chain; Region: SDH_alpha; cl12120
695560004360	L-serine deaminase [Amino acid transport and metabolism]; Region: SdaA; COG1760
695560004361	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
695560004362	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
695560004363	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
695560004364	substrate binding pocket [chemical binding]; other site
695560004365	membrane-bound complex binding site; other site
695560004366	hinge residues; other site
695560004367	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
695560004368	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
695560004369	Walker A/P-loop; other site
695560004370	ATP binding site [chemical binding]; other site
695560004371	Q-loop/lid; other site
695560004372	ABC transporter signature motif; other site
695560004373	Walker B; other site
695560004374	D-loop; other site
695560004375	H-loop/switch region; other site
695560004376	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
695560004377	dimer interface [polypeptide binding]; other site
695560004378	conserved gate region; other site
695560004379	putative PBP binding loops; other site
695560004380	ABC-ATPase subunit interface; other site
695560004381	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
695560004382	dimer interface [polypeptide binding]; other site
695560004383	conserved gate region; other site
695560004384	putative PBP binding loops; other site
695560004385	ABC-ATPase subunit interface; other site
695560004386	The substrate binding component of an ABC-type lactococcal OppA-like transport system contains; Region: PBP2_Lactococcal_OppA_like; cd08510
695560004387	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
695560004388	peptide binding site [polypeptide binding]; other site
695560004389	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
695560004390	Transposase; Region: HTH_Tnp_1; cl17663
695560004391	HTH-like domain; Region: HTH_21; pfam13276
695560004392	Integrase core domain; Region: rve; pfam00665
695560004393	Integrase core domain; Region: rve_2; pfam13333
695560004394	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
695560004395	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
695560004396	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
695560004397	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
695560004398	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
695560004399	active site
695560004400	ASC-1 homology or ASCH domain, a small beta-barrel domain found in all three kingdoms of life. ASCH resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as an RNA-binding domain during coactivation; Region: ASCH; cl01020
695560004401	Uncharacterized conserved protein [Function unknown]; Region: COG1479
695560004402	Protein of unknown function DUF262; Region: DUF262; pfam03235
695560004403	Protein of unknown function DUF262; Region: DUF262; pfam03235
695560004404	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
695560004405	Domain of unknown function (DUF4145); Region: DUF4145; pfam13643
695560004406	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: HsdR; COG4096
695560004407	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
695560004408	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
695560004409	ATP binding site [chemical binding]; other site
695560004410	putative Mg++ binding site [ion binding]; other site
695560004411	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
695560004412	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
695560004413	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
695560004414	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
695560004415	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
695560004416	active site
695560004417	DNA binding site [nucleotide binding]
695560004418	Int/Topo IB signature motif; other site
695560004419	HsdM N-terminal domain; Region: HsdM_N; pfam12161
695560004420	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
695560004421	Methyltransferase domain; Region: Methyltransf_26; pfam13659
695560004422	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
695560004423	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
695560004424	phosphate binding site [ion binding]; other site
695560004425	Helix-turn-helix domain of transposase family ISL3; Region: HTH_Tnp_ISL3; pfam13542
695560004426	Transposase; Region: DDE_Tnp_ISL3; pfam01610
695560004427	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
695560004428	potential frameshift: common BLAST hit: gi|58337695|ref|YP_194280.1| amino acid permease
695560004429	potential frameshift: common BLAST hit: gi|58337693|ref|YP_194278.1| pyrazinamidase-nicotinamidase
695560004430	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
695560004431	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
695560004432	Probable transposase; Region: OrfB_IS605; pfam01385
695560004433	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
695560004434	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cl00470
695560004435	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
695560004436	OsmC-like protein; Region: OsmC; pfam02566
695560004437	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
695560004438	putative substrate translocation pore; other site
695560004439	Major Facilitator Superfamily; Region: MFS_1; pfam07690
695560004440	potential frameshift: common BLAST hit: gi|58337702|ref|YP_194287.1| two-component response regulator
695560004441	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
695560004442	synthetase active site [active]
695560004443	NTP binding site [chemical binding]; other site
695560004444	metal binding site [ion binding]; metal-binding site
695560004445	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
695560004446	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
695560004447	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
695560004448	Major Facilitator Superfamily; Region: MFS_1; pfam07690
695560004449	putative substrate translocation pore; other site
695560004450	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
695560004451	potential frameshift: common BLAST hit: gi|268319942|ref|YP_003293598.1| Penicillin-binding protein
695560004452	Major Facilitator Superfamily; Region: MFS_1; pfam07690
695560004453	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
695560004454	putative substrate translocation pore; other site
695560004455	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
695560004456	Alpha amylase catalytic domain found in sucrose phosphorylase (also called sucrose glucosyltransferase, disaccharide glucosyltransferase, and sucrose-phosphate alpha-D glucosyltransferase); Region: AmyAc_Sucrose_phosphorylase; cd11355
695560004457	sucrose phosphorylase; Region: sucrose_gtfA; TIGR03852
695560004458	active site
695560004459	homodimer interface [polypeptide binding]; other site
695560004460	catalytic site [active]
695560004461	Alpha-galactosidase [Carbohydrate transport and metabolism]; Region: GalA; COG3345
695560004462	Melibiase; Region: Melibiase; pfam02065
695560004463	potential frameshift: common BLAST hit: gi|58337710|ref|YP_194295.1| ABC transporter nucleotide binding protein
695560004464	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
695560004465	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
695560004466	dimer interface [polypeptide binding]; other site
695560004467	conserved gate region; other site
695560004468	putative PBP binding loops; other site
695560004469	ABC-ATPase subunit interface; other site
695560004470	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
695560004471	dimer interface [polypeptide binding]; other site
695560004472	conserved gate region; other site
695560004473	putative PBP binding loops; other site
695560004474	ABC-ATPase subunit interface; other site
695560004475	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
695560004476	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
695560004477	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
695560004478	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
695560004479	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
695560004480	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
695560004481	active site
695560004482	catalytic residues [active]
695560004483	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK05270
695560004484	Galactose-1-phosphate uridyl transferase, N-terminal domain; Region: GalP_UDP_transf; pfam01087
695560004485	Galactose-1-phosphate uridyl transferase, C-terminal domain; Region: GalP_UDP_tr_C; pfam02744
695560004486	galactokinase; Provisional; Region: PRK05322
695560004487	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
695560004488	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
695560004489	Metallo-dependent hydrolases, subgroup A is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_A; cd01299
695560004490	Amidohydrolase; Region: Amidohydro_4; pfam13147
695560004491	active site
695560004492	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
695560004493	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
695560004494	peptide binding site [polypeptide binding]; other site
695560004495	Nitroreductase-like family 1. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_1; cd02137
695560004496	dimer interface [polypeptide binding]; other site
695560004497	FMN binding site [chemical binding]; other site
695560004498	Beta-galactosidase [Carbohydrate transport and metabolism]; Region: LacA; COG1874
695560004499	Beta-galactosidase; Region: Glyco_hydro_42; pfam02449
695560004500	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
695560004501	Beta-galactosidase C-terminal domain; Region: Glyco_hydro_42C; pfam08533
695560004502	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
695560004503	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
695560004504	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cl00162
695560004505	HPr interaction site; other site
695560004506	glycerol kinase (GK) interaction site [polypeptide binding]; other site
695560004507	active site
695560004508	phosphorylation site [posttranslational modification]
695560004509	Transcriptional regulators [Transcription]; Region: PurR; COG1609
695560004510	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
695560004511	DNA binding site [nucleotide binding]
695560004512	Ligand-binding domain of DNA transcription repressor GalR which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalR; cd01544
695560004513	putative dimerization interface [polypeptide binding]; other site
695560004514	putative ligand binding site [chemical binding]; other site
695560004515	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
695560004516	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
695560004517	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
695560004518	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
695560004519	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
695560004520	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
695560004521	NAD binding site [chemical binding]; other site
695560004522	homodimer interface [polypeptide binding]; other site
695560004523	active site
695560004524	substrate binding site [chemical binding]; other site
695560004525	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
695560004526	DNA binding site [nucleotide binding]
695560004527	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
695560004528	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
695560004529	Probable transposase; Region: OrfB_IS605; pfam01385
695560004530	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
695560004531	Transposase IS200 like; Region: Y1_Tnp; pfam01797
695560004532	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
695560004533	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
695560004534	Transcriptional regulators [Transcription]; Region: PurR; COG1609
695560004535	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
695560004536	putative substrate translocation pore; other site
695560004537	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
695560004538	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
695560004539	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
695560004540	Cystathionine beta-lyase family protein involved in aluminum resistance [Inorganic ion transport and metabolism]; Region: COG4100
695560004541	Aluminium resistance protein; Region: Alum_res; pfam06838
695560004542	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
695560004543	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
695560004544	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
695560004545	active site residue [active]
695560004546	Bacterial protein of unknown function (DUF910); Region: DUF910; pfam06014
695560004547	Rhomboid family; Region: Rhomboid; pfam01694
695560004548	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
695560004549	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
695560004550	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
695560004551	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
695560004552	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
695560004553	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
695560004554	Bacterial membrane protein YfhO; Region: YfhO; pfam09586
695560004555	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
695560004556	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
695560004557	nucleotide binding site [chemical binding]; other site
695560004558	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49); Region: G6PD_bact; pfam10786
695560004559	Bacterial low temperature requirement A protein (LtrA); Region: LtrA; cl01754
695560004560	Bacterial low temperature requirement A protein (LtrA); Region: LtrA; cl01754
695560004561	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
695560004562	peptidase T; Region: peptidase-T; TIGR01882
695560004563	metal binding site [ion binding]; metal-binding site
695560004564	dimer interface [polypeptide binding]; other site
695560004565	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
695560004566	tetramer (dimer of dimers) interface [polypeptide binding]; other site
695560004567	L-lactate dehydrogenase; Region: L-LDH-NAD; TIGR01771
695560004568	NAD binding site [chemical binding]; other site
695560004569	dimer interface [polypeptide binding]; other site
695560004570	substrate binding site [chemical binding]; other site
695560004571	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
695560004572	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
695560004573	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
695560004574	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
695560004575	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
695560004576	putative tRNA-binding site [nucleotide binding]; other site
695560004577	B3/4 domain; Region: B3_4; pfam03483
695560004578	tRNA synthetase B5 domain; Region: B5; smart00874
695560004579	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
695560004580	dimer interface [polypeptide binding]; other site
695560004581	motif 1; other site
695560004582	motif 3; other site
695560004583	motif 2; other site
695560004584	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
695560004585	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
695560004586	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
695560004587	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
695560004588	dimer interface [polypeptide binding]; other site
695560004589	motif 1; other site
695560004590	active site
695560004591	motif 2; other site
695560004592	motif 3; other site
695560004593	Predicted transcriptional regulators [Transcription]; Region: COG1733
695560004594	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
695560004595	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
695560004596	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
695560004597	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
695560004598	Acylphosphatase; Region: Acylphosphatase; pfam00708
695560004599	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
695560004600	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
695560004601	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
695560004602	dimerization interface [polypeptide binding]; other site
695560004603	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
695560004604	dimer interface [polypeptide binding]; other site
695560004605	phosphorylation site [posttranslational modification]
695560004606	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
695560004607	ATP binding site [chemical binding]; other site
695560004608	Mg2+ binding site [ion binding]; other site
695560004609	G-X-G motif; other site
695560004610	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
695560004611	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
695560004612	active site
695560004613	phosphorylation site [posttranslational modification]
695560004614	intermolecular recognition site; other site
695560004615	dimerization interface [polypeptide binding]; other site
695560004616	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
695560004617	DNA binding site [nucleotide binding]
695560004618	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
695560004619	Helix-turn-helix domain; Region: HTH_38; pfam13936
695560004620	Integrase core domain; Region: rve; pfam00665
695560004621	Uncharacterized ACR, COG1399; Region: DUF177; pfam02620
695560004622	hypothetical protein; Provisional; Region: PRK13670
695560004623	HIGH Nucleotidyl Transferase; Region: HIGH_NTase1; cl17673
695560004624	iojap-like ribosome-associated protein; Region: iojap_ybeB; TIGR00090
695560004625	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
695560004626	Zn2+ binding site [ion binding]; other site
695560004627	Mg2+ binding site [ion binding]; other site
695560004628	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
695560004629	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
695560004630	active site
695560004631	(T/H)XGH motif; other site
695560004632	GTPase YqeH; Provisional; Region: PRK13796
695560004633	Circularly permuted YqeH GTPase; Region: YqeH; cd01855
695560004634	GTP/Mg2+ binding site [chemical binding]; other site
695560004635	G4 box; other site
695560004636	G5 box; other site
695560004637	G1 box; other site
695560004638	Switch I region; other site
695560004639	G2 box; other site
695560004640	G3 box; other site
695560004641	Switch II region; other site
695560004642	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668; Region: YqeG_hyp_ppase
695560004643	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
695560004644	active site
695560004645	motif I; other site
695560004646	motif II; other site
695560004647	adenosine deaminase; Provisional; Region: PRK09358
695560004648	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
695560004649	active site
695560004650	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
695560004651	Transposase; Region: DDE_Tnp_ISL3; pfam01610
695560004652	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
695560004653	23S rRNA binding site [nucleotide binding]; other site
695560004654	L21 binding site [polypeptide binding]; other site
695560004655	L13 binding site [polypeptide binding]; other site
695560004656	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
695560004657	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
695560004658	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
695560004659	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
695560004660	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
695560004661	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
695560004662	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
695560004663	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
695560004664	active site
695560004665	dimer interface [polypeptide binding]; other site
695560004666	motif 1; other site
695560004667	motif 2; other site
695560004668	motif 3; other site
695560004669	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
695560004670	anticodon binding site; other site
695560004671	primosomal protein DnaI; Reviewed; Region: PRK08939
695560004672	Primosomal protein DnaI N-terminus; Region: DnaI_N; pfam07319
695560004673	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
695560004674	Walker A motif; other site
695560004675	ATP binding site [chemical binding]; other site
695560004676	Walker B motif; other site
695560004677	Replication initiation/membrane attachment protein [DNA replication, recombination, and repair]; Region: DnaB; COG3611
695560004678	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
695560004679	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
695560004680	ATP cone domain; Region: ATP-cone; pfam03477
695560004681	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
695560004682	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
695560004683	CoA-binding site [chemical binding]; other site
695560004684	ATP-binding [chemical binding]; other site
695560004685	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
695560004686	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
695560004687	DNA binding site [nucleotide binding]
695560004688	catalytic residue [active]
695560004689	H2TH interface [polypeptide binding]; other site
695560004690	putative catalytic residues [active]
695560004691	turnover-facilitating residue; other site
695560004692	intercalation triad [nucleotide binding]; other site
695560004693	8OG recognition residue [nucleotide binding]; other site
695560004694	putative reading head residues; other site
695560004695	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
695560004696	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
695560004697	DNA polymerase I; Provisional; Region: PRK05755
695560004698	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
695560004699	active site
695560004700	metal binding site 1 [ion binding]; metal-binding site
695560004701	putative 5' ssDNA interaction site; other site
695560004702	metal binding site 3; metal-binding site
695560004703	metal binding site 2 [ion binding]; metal-binding site
695560004704	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
695560004705	putative DNA binding site [nucleotide binding]; other site
695560004706	putative metal binding site [ion binding]; other site
695560004707	inactive DEDDy 3'-5' exonuclease domain of Bacillus stearothermophilus DNA polymerase I and similar family-A DNA polymerases; Region: DNA_polA_I_Bacillus_like_exo; cd06140
695560004708	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
695560004709	active site
695560004710	DNA binding site [nucleotide binding]
695560004711	catalytic site [active]
695560004712	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
695560004713	PTS system sorbose-specific iic component; Region: EII-Sor; pfam03609
695560004714	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cl00021
695560004715	active site
695560004716	phosphorylation site [posttranslational modification]
695560004717	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
695560004718	active pocket/dimerization site; other site
695560004719	active site
695560004720	phosphorylation site [posttranslational modification]
695560004721	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
695560004722	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
695560004723	ligand binding site [chemical binding]; other site
695560004724	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
695560004725	Histidine kinase; Region: HisKA_3; pfam07730
695560004726	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
695560004727	ATP binding site [chemical binding]; other site
695560004728	Mg2+ binding site [ion binding]; other site
695560004729	G-X-G motif; other site
695560004730	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
695560004731	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
695560004732	active site
695560004733	phosphorylation site [posttranslational modification]
695560004734	intermolecular recognition site; other site
695560004735	dimerization interface [polypeptide binding]; other site
695560004736	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
695560004737	DNA binding residues [nucleotide binding]
695560004738	dimerization interface [polypeptide binding]; other site
695560004739	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
695560004740	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
695560004741	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
695560004742	intersubunit interface [polypeptide binding]; other site
695560004743	active site
695560004744	catalytic residue [active]
695560004745	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
695560004746	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
695560004747	DNA-binding site [nucleotide binding]; DNA binding site
695560004748	UTRA domain; Region: UTRA; pfam07702
695560004749	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
695560004750	active site
695560004751	intersubunit interactions; other site
695560004752	catalytic residue [active]
695560004753	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
695560004754	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
695560004755	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
695560004756	Cadherin-like beta sandwich domain; Region: Cadherin-like; pfam12733
695560004757	Glycosyl hydrolases family 32; Region: Glyco_32; smart00640
695560004758	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
695560004759	substrate binding [chemical binding]; other site
695560004760	active site
695560004761	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
695560004762	Bacterial Ig-like domain (group 2); Region: Big_2; cl02708
695560004763	Bacterial surface layer protein; Region: SLAP; pfam03217
695560004764	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
695560004765	Helix-turn-helix domain; Region: HTH_38; pfam13936
695560004766	Integrase core domain; Region: rve; pfam00665
695560004767	Acetyltransferase (GNAT) domain; Region: Acetyltransf_8; pfam13523
695560004768	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
695560004769	Coenzyme A binding pocket [chemical binding]; other site
695560004770	RNAP_Rpb7_N_like: This conserved domain represents the N-terminal ribonucleoprotein (RNP) domain of the Rpb7 subunit of eukaryotic RNA polymerase (RNAP) II and its homologs, Rpa43 of eukaryotic RNAP I, Rpc25 of eukaryotic RNAP III, and RpoE (subunit E)...; Region: RNAP_Rpb7_N_like; cl04309
695560004771	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
695560004772	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
695560004773	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
695560004774	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
695560004775	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
695560004776	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
695560004777	purine monophosphate binding site [chemical binding]; other site
695560004778	dimer interface [polypeptide binding]; other site
695560004779	putative catalytic residues [active]
695560004780	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
695560004781	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
695560004782	Folate-dependent phosphoribosylglycinamide formyltransferase PurN [Nucleotide transport and metabolism]; Region: PurN; COG0299
695560004783	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
695560004784	active site
695560004785	substrate binding site [chemical binding]; other site
695560004786	cosubstrate binding site; other site
695560004787	catalytic site [active]
695560004788	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
695560004789	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
695560004790	dimerization interface [polypeptide binding]; other site
695560004791	putative ATP binding site [chemical binding]; other site
695560004792	amidophosphoribosyltransferase; Provisional; Region: PRK07272
695560004793	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
695560004794	active site
695560004795	tetramer interface [polypeptide binding]; other site
695560004796	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
695560004797	active site
695560004798	phosphoribosylformylglycinamidine synthase II; Provisional; Region: PRK01213
695560004799	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
695560004800	dimerization interface [polypeptide binding]; other site
695560004801	ATP binding site [chemical binding]; other site
695560004802	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
695560004803	dimerization interface [polypeptide binding]; other site
695560004804	ATP binding site [chemical binding]; other site
695560004805	phosphoribosylformylglycinamidine synthase I; Provisional; Region: PRK03619
695560004806	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
695560004807	putative active site [active]
695560004808	catalytic triad [active]
695560004809	Phosphoribosylformylglycinamidine (FGAM) synthase; Region: PurS; pfam02700
695560004810	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
695560004811	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
695560004812	ATP binding site [chemical binding]; other site
695560004813	active site
695560004814	substrate binding site [chemical binding]; other site
695560004815	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
695560004816	ATP-grasp domain; Region: ATP-grasp; pfam02222
695560004817	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
695560004818	formate--tetrahydrofolate ligase; Provisional; Region: PRK13505
695560004819	Formyltetrahydrofolate synthetase (FTHFS) catalyzes the ATP-dependent activation of formate ion via its addition to the N10 position of tetrahydrofolate. FTHFS is a highly expressed key enzyme in both the Wood-Ljungdahl pathway of autotrophic CO2...; Region: FTHFS; cd00477
695560004820	Potassium binding sites [ion binding]; other site
695560004821	Cesium cation binding sites [ion binding]; other site
695560004822	HflC protein; Region: hflC; TIGR01932
695560004823	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
695560004824	RelB antitoxin; Region: RelB; cl01171
695560004825	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
695560004826	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
695560004827	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
695560004828	Probable transposase; Region: OrfB_IS605; pfam01385
695560004829	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
695560004830	Peptidase M1 family containing bacterial Aminopeptidase N; Region: M1_APN_5; cd09604
695560004831	Zn binding site [ion binding]; other site
695560004832	amino-acid N-acetyltransferase; Region: PLN02825
695560004833	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
695560004834	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
695560004835	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
695560004836	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
695560004837	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
695560004838	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
695560004839	Bacterial surface layer protein; Region: SLAP; pfam03217
695560004840	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
695560004841	putative tRNA-binding site [nucleotide binding]; other site
695560004842	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
695560004843	catalytic residues [active]
695560004844	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
695560004845	S-adenosylmethionine binding site [chemical binding]; other site
695560004846	Bacterial ABC transporter protein EcsB; Region: EcsB; pfam05975
695560004847	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
695560004848	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
695560004849	Walker A/P-loop; other site
695560004850	ATP binding site [chemical binding]; other site
695560004851	Q-loop/lid; other site
695560004852	ABC transporter signature motif; other site
695560004853	Walker B; other site
695560004854	D-loop; other site
695560004855	H-loop/switch region; other site
695560004856	HINT (histidine triad nucleotide-binding protein) subgroup: Members of this CD belong to the superfamily of histidine triad hydrolases that act on alpha-phosphate of ribonucleotides. This subgroup includes members from all three forms of cellular life; Region: HINT_subgroup; cd01277
695560004857	HIT family signature motif; other site
695560004858	catalytic residue [active]
695560004859	peptidylprolyl isomerase; Provisional; Region: prsA; PRK04405
695560004860	SurA N-terminal domain; Region: SurA_N_3; cl07813
695560004861	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
695560004862	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
695560004863	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
695560004864	3'-5' exoribonuclease YhaM; Provisional; Region: PRK13480
695560004865	YhaM_OBF_like: A subfamily of OB folds similar to that found in Bacillus subtilis YhaM and Staphylococcus aureus cmp-binding factor-1 (SaCBF1). Both these proteins are 3'-to-5'exoribonucleases. YhaM requires Mn2+ or Co2+ for activity and is...; Region: YhaM_OBF_like; cd04492
695560004866	generic binding surface I; other site
695560004867	generic binding surface II; other site
695560004868	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
695560004869	Zn2+ binding site [ion binding]; other site
695560004870	Mg2+ binding site [ion binding]; other site
695560004871	P-loop containing region of AAA domain; Region: AAA_29; cl17516
695560004872	AAA domain; Region: AAA_23; pfam13476
695560004873	Protein of unknown function (DUF972); Region: DUF972; pfam06156
695560004874	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
695560004875	DNA repair exonuclease [DNA replication, recombination, and repair]; Region: SbcD; COG0420
695560004876	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
695560004877	active site
695560004878	metal binding site [ion binding]; metal-binding site
695560004879	DNA binding site [nucleotide binding]
695560004880	hypothetical protein; Provisional; Region: PRK13676
695560004881	Transglycosylase; Region: Transgly; pfam00912
695560004882	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
695560004883	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
695560004884	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
695560004885	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
695560004886	active site
695560004887	Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate...; Region: alpha_hydroxyacid_oxid_FMN; cd02809
695560004888	active site
695560004889	substrate binding site [chemical binding]; other site
695560004890	FMN-dependent dehydrogenase; Region: FMN_dh; pfam01070
695560004891	FMN binding site [chemical binding]; other site
695560004892	putative catalytic residues [active]
695560004893	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
695560004894	amphipathic channel; other site
695560004895	Asn-Pro-Ala signature motifs; other site
695560004896	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
695560004897	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
695560004898	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
695560004899	beta-galactosidase; Region: BGL; TIGR03356
695560004900	Acyl transferase domain; Region: Acyl_transf_1; cl08282
695560004901	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
695560004902	dimerization interface [polypeptide binding]; other site
695560004903	Acyltransferase family; Region: Acyl_transf_3; pfam01757
695560004904	Herpesvirus latent membrane protein 1 (LMP1); Region: Herpes_LMP1; pfam05297
695560004905	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
695560004906	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
695560004907	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
695560004908	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
695560004909	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
695560004910	putative active site [active]
695560004911	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
695560004912	Domain of unknown function (DUF1836); Region: DUF1836; pfam08876
695560004913	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
695560004914	Major Facilitator Superfamily; Region: MFS_1; pfam07690
695560004915	putative substrate translocation pore; other site
695560004916	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
695560004917	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
695560004918	ligand binding site [chemical binding]; other site
695560004919	flexible hinge region; other site
695560004920	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
695560004921	putative switch regulator; other site
695560004922	non-specific DNA interactions [nucleotide binding]; other site
695560004923	DNA binding site [nucleotide binding]
695560004924	sequence specific DNA binding site [nucleotide binding]; other site
695560004925	putative cAMP binding site [chemical binding]; other site
695560004926	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
695560004927	intersubunit interface [polypeptide binding]; other site
695560004928	active site
695560004929	zinc binding site [ion binding]; other site
695560004930	Na+ binding site [ion binding]; other site
695560004931	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
695560004932	arginyl-tRNA synthetase; Reviewed; Region: PRK12451
695560004933	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
695560004934	active site
695560004935	HIGH motif; other site
695560004936	KMSK motif region; other site
695560004937	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
695560004938	tRNA binding surface [nucleotide binding]; other site
695560004939	anticodon binding site; other site
695560004940	Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376
695560004941	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
695560004942	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
695560004943	putative substrate binding site [chemical binding]; other site
695560004944	putative ATP binding site [chemical binding]; other site
695560004945	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
695560004946	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
695560004947	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
695560004948	PspC domain; Region: PspC; pfam04024
695560004949	ADP-ribose pyrophosphatase [Nucleotide transport and metabolism]; Region: COG1051
695560004950	nudix motif; other site
695560004951	Uncharacterized conserved protein [General function prediction only]; Region: COG4111
695560004952	nicotinate phosphoribosyltransferase; Validated; Region: PRK09243
695560004953	Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction...; Region: NAPRTase_A; cd01570
695560004954	active site
695560004955	Isochorismatase family; Region: Isochorismatase; pfam00857
695560004956	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
695560004957	catalytic triad [active]
695560004958	conserved cis-peptide bond; other site
695560004959	Transposase, Mutator family; Region: Transposase_mut; pfam00872
695560004960	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
695560004961	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
695560004962	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
695560004963	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
695560004964	HIGH motif; other site
695560004965	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
695560004966	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
695560004967	active site
695560004968	KMSKS motif; other site
695560004969	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
695560004970	tRNA binding surface [nucleotide binding]; other site
695560004971	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
695560004972	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
695560004973	active site
695560004974	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
695560004975	Major Facilitator Superfamily; Region: MFS_1; pfam07690
695560004976	putative substrate translocation pore; other site
695560004977	S-adenosylmethionine synthetase; Validated; Region: PRK05250
695560004978	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
695560004979	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
695560004980	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
695560004981	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
695560004982	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
695560004983	intersubunit interface [polypeptide binding]; other site
695560004984	seryl-tRNA synthetase; Provisional; Region: PRK05431
695560004985	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
695560004986	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
695560004987	dimer interface [polypeptide binding]; other site
695560004988	active site
695560004989	motif 1; other site
695560004990	motif 2; other site
695560004991	motif 3; other site
695560004992	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
695560004993	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
695560004994	Uncharacterized conserved protein [Function unknown]; Region: COG0398
695560004995	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
695560004996	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
695560004997	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
695560004998	non-specific DNA binding site [nucleotide binding]; other site
695560004999	salt bridge; other site
695560005000	sequence-specific DNA binding site [nucleotide binding]; other site
695560005001	Nucleoside 2-deoxyribosyltransferase; Region: Nuc_deoxyrib_tr; pfam05014
695560005002	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
695560005003	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
695560005004	NAD(P) binding site [chemical binding]; other site
695560005005	catalytic residues [active]
695560005006	prokaryotic 3-carboxy-cis,cis-muconate cycloisomerase (CMLE)_like; Region: pCLME; cd01597
695560005007	Adenylosuccinate lyase [Nucleotide transport and metabolism]; Region: PurB; COG0015
695560005008	tetramer interface [polypeptide binding]; other site
695560005009	active site
695560005010	Transcriptional regulator [Transcription]; Region: LysR; COG0583
695560005011	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
695560005012	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
695560005013	Transcriptional regulator [Transcription]; Region: LysR; COG0583
695560005014	dimerization interface [polypeptide binding]; other site
695560005015	Gram-positive signal peptide, YSIRK family; Region: YSIRK_signal; TIGR01168
695560005016	Double zinc ribbon; Region: DZR; pfam12773
695560005017	zinc-ribbon domain; Region: zinc_ribbon_2; pfam13240
695560005018	MMPL family; Region: MMPL; pfam03176
695560005019	X-X-X-Leu-X-X-Gly heptad repeats; Region: xxxLxxG_by_4; TIGR03057
695560005020	X-X-X-Leu-X-X-Gly heptad repeats; Region: xxxLxxG_by_4; TIGR03057
695560005021	X-X-X-Leu-X-X-Gly heptad repeats; Region: xxxLxxG_by_4; TIGR03057
695560005022	Predicted drug exporters of the RND superfamily [General function prediction only]; Region: COG2409
695560005023	X-X-X-Leu-X-X-Gly heptad repeats; Region: xxxLxxG_by_4; TIGR03057
695560005024	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
695560005025	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
695560005026	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
695560005027	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
695560005028	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
695560005029	uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u2; cd12827
695560005030	Cl binding site [ion binding]; other site
695560005031	oligomer interface [polypeptide binding]; other site
695560005032	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
695560005033	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
695560005034	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
695560005035	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
695560005036	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
695560005037	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
695560005038	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
695560005039	dimer interface [polypeptide binding]; other site
695560005040	conserved gate region; other site
695560005041	ABC-ATPase subunit interface; other site
695560005042	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
695560005043	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
695560005044	dimer interface [polypeptide binding]; other site
695560005045	conserved gate region; other site
695560005046	putative PBP binding loops; other site
695560005047	ABC-ATPase subunit interface; other site
695560005048	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
695560005049	ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259
695560005050	Walker A/P-loop; other site
695560005051	ATP binding site [chemical binding]; other site
695560005052	Q-loop/lid; other site
695560005053	ABC transporter signature motif; other site
695560005054	Walker B; other site
695560005055	D-loop; other site
695560005056	H-loop/switch region; other site
695560005057	TOBE domain; Region: TOBE_2; pfam08402
695560005058	Peptidase family C69; Region: Peptidase_C69; pfam03577
695560005059	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
695560005060	DNA/RNA non-specific endonuclease; Region: Endonuclea_NS_2; cl17626
695560005061	DNA polymerase III subunit epsilon; Validated; Region: PRK06195
695560005062	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
695560005063	active site
695560005064	catalytic site [active]
695560005065	substrate binding site [chemical binding]; other site
695560005066	NAD-dependent protein deacetylases, SIR2 family [Transcription]; Region: SIR2; COG0846
695560005067	Predicted membrane protein [Function unknown]; Region: COG2323
695560005068	Protein of unknown function (DUF3290); Region: DUF3290; pfam11694
695560005069	Glucan-binding protein C; Region: GbpC; pfam08363
695560005070	MucBP domain; Region: MucBP; pfam06458
695560005071	MucBP domain; Region: MucBP; pfam06458
695560005072	Nicotinamide mononucleotide transporter; Region: NMN_transporter; pfam04973
695560005073	choice-of-anchor A domain; Region: choice_anch_A; TIGR04215
695560005074	PAS domain; Region: PAS_10; pfam13596
695560005075	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
695560005076	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
695560005077	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
695560005078	Walker A/P-loop; other site
695560005079	ATP binding site [chemical binding]; other site
695560005080	Q-loop/lid; other site
695560005081	ABC transporter signature motif; other site
695560005082	Walker B; other site
695560005083	D-loop; other site
695560005084	H-loop/switch region; other site
695560005085	proline-specific peptidase, Bacillus coagulans-type subfamily; Region: pro_imino_pep_2; TIGR01250
695560005086	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
695560005087	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
695560005088	active site
695560005089	phosphorylation site [posttranslational modification]
695560005090	intermolecular recognition site; other site
695560005091	dimerization interface [polypeptide binding]; other site
695560005092	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
695560005093	DNA binding site [nucleotide binding]
695560005094	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
695560005095	HAMP domain; Region: HAMP; pfam00672
695560005096	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
695560005097	dimer interface [polypeptide binding]; other site
695560005098	phosphorylation site [posttranslational modification]
695560005099	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
695560005100	ATP binding site [chemical binding]; other site
695560005101	Mg2+ binding site [ion binding]; other site
695560005102	G-X-G motif; other site
695560005103	Predicted membrane protein [Function unknown]; Region: COG3212
695560005104	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
695560005105	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
695560005106	Predicted membrane protein [Function unknown]; Region: COG3212
695560005107	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
695560005108	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
695560005109	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
695560005110	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
695560005111	Coenzyme A binding pocket [chemical binding]; other site
695560005112	Transcriptional regulators [Transcription]; Region: MarR; COG1846
695560005113	MarR family; Region: MarR; pfam01047
695560005114	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
695560005115	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
695560005116	peptide binding site [polypeptide binding]; other site
695560005117	Protein of unknown function (DUF1304); Region: DUF1304; pfam06993
695560005118	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
695560005119	elongation factor P; Validated; Region: PRK00529
695560005120	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
695560005121	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
695560005122	RNA binding site [nucleotide binding]; other site
695560005123	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
695560005124	RNA binding site [nucleotide binding]; other site
695560005125	pantothenate kinase; Provisional; Region: PRK05439
695560005126	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
695560005127	ATP-binding site [chemical binding]; other site
695560005128	CoA-binding site [chemical binding]; other site
695560005129	Mg2+-binding site [ion binding]; other site
695560005130	GDSL-like Lipase/Acylhydrolase family; Region: Lipase_GDSL_2; pfam13472
695560005131	active site
695560005132	catalytic triad [active]
695560005133	oxyanion hole [active]
695560005134	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
695560005135	Coenzyme A binding pocket [chemical binding]; other site
695560005136	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
695560005137	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
695560005138	substrate binding pocket [chemical binding]; other site
695560005139	membrane-bound complex binding site; other site
695560005140	hinge residues; other site
695560005141	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
695560005142	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
695560005143	Walker A/P-loop; other site
695560005144	ATP binding site [chemical binding]; other site
695560005145	Q-loop/lid; other site
695560005146	ABC transporter signature motif; other site
695560005147	Walker B; other site
695560005148	D-loop; other site
695560005149	H-loop/switch region; other site
695560005150	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
695560005151	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
695560005152	dimer interface [polypeptide binding]; other site
695560005153	conserved gate region; other site
695560005154	putative PBP binding loops; other site
695560005155	ABC-ATPase subunit interface; other site
695560005156	Superfamily I DNA and RNA helicases [General function prediction only]; Region: COG3973
695560005157	Part of AAA domain; Region: AAA_19; pfam13245
695560005158	Family description; Region: UvrD_C_2; pfam13538
695560005159	Zinc-dependent metalloprotease, MMP_like subfamily. This group contains matrix metalloproteinases (MMPs), serralysins, and the astacin_like family of proteases; Region: ZnMc_MMP_like; cd04268
695560005160	active site
695560005161	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
695560005162	catalytic core [active]
695560005163	FtsX-like permease family; Region: FtsX; pfam02687
695560005164	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
695560005165	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
695560005166	Walker A/P-loop; other site
695560005167	ATP binding site [chemical binding]; other site
695560005168	Q-loop/lid; other site
695560005169	ABC transporter signature motif; other site
695560005170	Walker B; other site
695560005171	D-loop; other site
695560005172	H-loop/switch region; other site
695560005173	Predicted membrane protein [Function unknown]; Region: COG4640
695560005174	type I restriction enzyme EcoKI subunit R; Provisional; Region: hsdR; PRK11448
695560005175	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
695560005176	active pocket/dimerization site; other site
695560005177	active site
695560005178	phosphorylation site [posttranslational modification]
695560005179	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
695560005180	active site
695560005181	homodimer interface [polypeptide binding]; other site
695560005182	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
695560005183	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
695560005184	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
695560005185	putative active site [active]
695560005186	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
695560005187	Glycoside Hydrolases Family 4; GlvA- and pagL-like glycosidases; Region: GH4_GlvA_pagL_like; cd05298
695560005188	NAD binding site [chemical binding]; other site
695560005189	sugar binding site [chemical binding]; other site
695560005190	divalent metal binding site [ion binding]; other site
695560005191	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
695560005192	dimer interface [polypeptide binding]; other site
695560005193	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
695560005194	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
695560005195	Coenzyme A binding pocket [chemical binding]; other site
695560005196	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
695560005197	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
695560005198	active site
695560005199	tetramer interface; other site
695560005200	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
695560005201	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
695560005202	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
695560005203	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
695560005204	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
695560005205	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
695560005206	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
695560005207	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
695560005208	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
695560005209	This family is most closely related to the GT1 family of glycosyltransferases. capH in Staphylococcus aureus has been shown to be required for the biosynthesis of the type 1 capsular polysaccharide (CP1); Region: GT1_CapH_like; cd03812
695560005210	putative ADP-binding pocket [chemical binding]; other site
695560005211	LicD family; Region: LicD; cl01378
695560005212	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
695560005213	Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128
695560005214	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
695560005215	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
695560005216	active site
695560005217	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
695560005218	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
695560005219	trimer interface [polypeptide binding]; other site
695560005220	CoA binding site [chemical binding]; other site
695560005221	active site
695560005222	putative glycosyl transferase; Provisional; Region: PRK10073
695560005223	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
695560005224	active site
695560005225	Capsular polysaccharide synthesis protein; Region: Caps_synth; pfam05704
695560005226	Glycosyltransferase family 28 C-terminal domain; Region: Glyco_tran_28_C; pfam04101
695560005227	Core-2/I-Branching enzyme; Region: Branch; pfam02485
695560005228	Oligosaccharide biosynthesis protein Alg14 like; Region: Alg14; pfam08660
695560005229	Bacterial sugar transferase; Region: Bac_transf; pfam02397
695560005230	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
695560005231	RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321
695560005232	NADP binding site [chemical binding]; other site
695560005233	active site
695560005234	putative substrate binding site [chemical binding]; other site
695560005235	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
695560005236	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
695560005237	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
695560005238	substrate binding site; other site
695560005239	tetramer interface; other site
695560005240	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
695560005241	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
695560005242	NAD binding site [chemical binding]; other site
695560005243	substrate binding site [chemical binding]; other site
695560005244	homodimer interface [polypeptide binding]; other site
695560005245	active site
695560005246	Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA; Region: HTH_TipAL-Mta; cd01106
695560005247	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
695560005248	DNA binding residues [nucleotide binding]
695560005249	dimer interface [polypeptide binding]; other site
695560005250	Methyltransferase domain; Region: Methyltransf_31; pfam13847
695560005251	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
695560005252	S-adenosylmethionine binding site [chemical binding]; other site
695560005253	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
695560005254	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
695560005255	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
695560005256	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
695560005257	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
695560005258	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
695560005259	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
695560005260	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
695560005261	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
695560005262	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
695560005263	Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128
695560005264	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
695560005265	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_d; cd04196
695560005266	Probable Catalytic site; other site
695560005267	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
695560005268	Helix-turn-helix domain; Region: HTH_38; pfam13936
695560005269	Integrase core domain; Region: rve; pfam00665
695560005270	potential frameshift: common BLAST hit: gi|302671772|ref|YP_003831732.1| glycosyl transferase GT2 family protein
695560005271	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
695560005272	L-rhamnosyltransferase; Region: rhamnosyltran; TIGR01556
695560005273	active site
695560005274	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
695560005275	active site
695560005276	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
695560005277	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
695560005278	L-rhamnosyltransferase; Region: rhamnosyltran; TIGR01556
695560005279	active site
695560005280	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
695560005281	This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808
695560005282	putative ADP-binding pocket [chemical binding]; other site
695560005283	Bacterial sugar transferase; Region: Bac_transf; pfam02397
695560005284	Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: CapC; COG4464
695560005285	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
695560005286	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
695560005287	Nucleotide binding site [chemical binding]; other site
695560005288	DTAP/Switch II; other site
695560005289	Switch I; other site
695560005290	Chain length determinant protein; Region: Wzz; cl15801
695560005291	Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane]; Region: COG3944
695560005292	Cell envelope-related transcriptional attenuator domain; Region: LytR_cpsA_psr; cl00581
695560005293	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
695560005294	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
695560005295	HflX GTPase family; Region: HflX; cd01878
695560005296	G1 box; other site
695560005297	GTP/Mg2+ binding site [chemical binding]; other site
695560005298	Switch I region; other site
695560005299	G2 box; other site
695560005300	G3 box; other site
695560005301	Switch II region; other site
695560005302	G4 box; other site
695560005303	G5 box; other site
695560005304	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
695560005305	Gram-positive signal peptide, YSIRK family; Region: YSIRK_signal; TIGR01168
695560005306	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
695560005307	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
695560005308	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
695560005309	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
695560005310	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
695560005311	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
695560005312	Type IV secretory pathway, VirD4 components [Intracellular trafficking and secretion]; Region: VirD4; COG3505
695560005313	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
695560005314	Walker A motif; other site
695560005315	ATP binding site [chemical binding]; other site
695560005316	RNase H is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a sequence non-specific manner; Region: RNase_H; cl14782
695560005317	RNA/DNA hybrid binding site [nucleotide binding]; other site
695560005318	active site
695560005319	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
695560005320	NlpC/P60 family; Region: NLPC_P60; pfam00877
695560005321	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
695560005322	NlpC/P60 family; Region: NLPC_P60; pfam00877
695560005323	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
695560005324	NlpC/P60 family; Region: NLPC_P60; pfam00877
695560005325	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
695560005326	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
695560005327	catalytic site [active]
695560005328	G-X2-G-X-G-K; other site
695560005329	Uncharacterized protein conserved in bacteria (DUF2187); Region: DUF2187; cl11556
695560005330	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39A; cd02549
695560005331	putative active site [active]
695560005332	Protein of unknown function (DUF3815); Region: DUF3815; pfam12821
695560005333	Uncharacterized conserved protein [Function unknown]; Region: COG2966
695560005334	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
695560005335	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
695560005336	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
695560005337	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
695560005338	Walker A/P-loop; other site
695560005339	ATP binding site [chemical binding]; other site
695560005340	Q-loop/lid; other site
695560005341	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
695560005342	ABC transporter signature motif; other site
695560005343	Walker B; other site
695560005344	D-loop; other site
695560005345	ABC transporter; Region: ABC_tran_2; pfam12848
695560005346	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
695560005347	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
695560005348	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
695560005349	Protein of unknown function (DUF554); Region: DUF554; pfam04474
695560005350	Cell envelope-related transcriptional attenuator domain; Region: LytR_cpsA_psr; cl00581
695560005351	oligoendopeptidase F; Region: pepF; TIGR00181
695560005352	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_3; cd09608
695560005353	active site
695560005354	Zn binding site [ion binding]; other site
695560005355	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
695560005356	CAAX protease self-immunity; Region: Abi; pfam02517
695560005357	L-lactate permease; Region: Lactate_perm; cl00701
695560005358	L-lactate permease [Energy production and conversion]; Region: LldP; COG1620
695560005359	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
695560005360	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
695560005361	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cl00462
695560005362	dimer interface [polypeptide binding]; other site
695560005363	putative PBP binding regions; other site
695560005364	ABC-ATPase subunit  interface; other site
695560005365	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
695560005366	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
695560005367	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
695560005368	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
695560005369	intersubunit interface [polypeptide binding]; other site
695560005370	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
695560005371	dimerization interface [polypeptide binding]; other site
695560005372	putative DNA binding site [nucleotide binding]; other site
695560005373	putative Zn2+ binding site [ion binding]; other site
695560005374	LytTr DNA-binding domain; Region: LytTR; pfam04397
695560005375	Protein of unknown function (DUF3021); Region: DUF3021; pfam11457
695560005376	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
695560005377	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
695560005378	active site
695560005379	phosphorylation site [posttranslational modification]
695560005380	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
695560005381	active site
695560005382	P-loop; other site
695560005383	phosphorylation site [posttranslational modification]
695560005384	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
695560005385	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
695560005386	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
695560005387	putative substrate binding site [chemical binding]; other site
695560005388	putative ATP binding site [chemical binding]; other site
695560005389	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
695560005390	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
695560005391	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
695560005392	potential frameshift: common BLAST hit: gi|213693252|ref|YP_002323838.1| filamentation induced by cAMP protein Fic
695560005393	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
695560005394	salt bridge; other site
695560005395	non-specific DNA binding site [nucleotide binding]; other site
695560005396	sequence-specific DNA binding site [nucleotide binding]; other site
695560005397	putative alpha-glucosidase; Provisional; Region: PRK10658
695560005398	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
695560005399	Alpha-glucosidase II (alpha-D-glucoside glucohydrolase) is a glycosyl hydrolase family 31 (GH31) enzyme, found in bacteria and plants, which has exo-alpha-1,4-glucosidase and oligo-1,6-glucosidase activities. Alpha-glucosidase II has been characterized...; Region: GH31_glucosidase_II_MalA; cd06604
695560005400	trimer interface [polypeptide binding]; other site
695560005401	active site
695560005402	homohexamer (dimer of homotrimer) interface [polypeptide binding]; other site
695560005403	catalytic site [active]
695560005404	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
695560005405	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
695560005406	Probable transposase; Region: OrfB_IS605; pfam01385
695560005407	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
695560005408	Sec23/Sec24 zinc finger; Region: zf-Sec23_Sec24; pfam04810
695560005409	Enterocin A Immunity; Region: EntA_Immun; pfam08951
695560005410	L-Lactate oxidase (LOX) FMN-binding domain. LOX is a member of the family of FMN-containing alpha-hydroxyacid oxidases and catalyzes the oxidation of l-lactate using molecular oxygen to generate pyruvate and H2O2.  This family occurs in both prokaryotes...; Region: LOX_like_FMN; cd04737
695560005411	teramer interface [polypeptide binding]; other site
695560005412	FMN-dependent dehydrogenase; Region: FMN_dh; pfam01070
695560005413	active site
695560005414	FMN binding site [chemical binding]; other site
695560005415	catalytic residues [active]
695560005416	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
695560005417	aspartate racemase; Region: asp_race; TIGR00035
695560005418	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
695560005419	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
695560005420	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
695560005421	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
695560005422	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
695560005423	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
695560005424	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
695560005425	dimer interface [polypeptide binding]; other site
695560005426	phosphorylation site [posttranslational modification]
695560005427	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
695560005428	ATP binding site [chemical binding]; other site
695560005429	Mg2+ binding site [ion binding]; other site
695560005430	G-X-G motif; other site
695560005431	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
695560005432	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
695560005433	active site
695560005434	phosphorylation site [posttranslational modification]
695560005435	intermolecular recognition site; other site
695560005436	dimerization interface [polypeptide binding]; other site
695560005437	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
695560005438	DNA binding site [nucleotide binding]
695560005439	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
695560005440	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
695560005441	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
695560005442	Walker A/P-loop; other site
695560005443	ATP binding site [chemical binding]; other site
695560005444	Q-loop/lid; other site
695560005445	ABC transporter signature motif; other site
695560005446	Walker B; other site
695560005447	D-loop; other site
695560005448	H-loop/switch region; other site
695560005449	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
695560005450	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
695560005451	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
695560005452	Walker A/P-loop; other site
695560005453	ATP binding site [chemical binding]; other site
695560005454	Q-loop/lid; other site
695560005455	ABC transporter signature motif; other site
695560005456	Walker B; other site
695560005457	D-loop; other site
695560005458	H-loop/switch region; other site
695560005459	Protein of unknown function (DUF1129); Region: DUF1129; pfam06570
695560005460	GTP-binding protein YchF; Reviewed; Region: PRK09601
695560005461	YchF GTPase; Region: YchF; cd01900
695560005462	G1 box; other site
695560005463	GTP/Mg2+ binding site [chemical binding]; other site
695560005464	Switch I region; other site
695560005465	G2 box; other site
695560005466	Switch II region; other site
695560005467	G3 box; other site
695560005468	G4 box; other site
695560005469	G5 box; other site
695560005470	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
695560005471	Bacterial protein of unknown function (DUF951); Region: DUF951; pfam06107
695560005472	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
695560005473	ParB-like nuclease domain; Region: ParB; smart00470
695560005474	Helix-turn-helix; Region: HTH_3; pfam01381
695560005475	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
695560005476	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
695560005477	nucleoid occlusion protein; Region: nucleoid_noc; TIGR04285
695560005478	ParB-like nuclease domain; Region: ParBc; pfam02195
695560005479	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
695560005480	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
695560005481	S-adenosylmethionine binding site [chemical binding]; other site
695560005482	Colicin V production protein; Region: Colicin_V; pfam02674
695560005483	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
695560005484	ApbE family; Region: ApbE; pfam02424
695560005485	Tyrosine phosphatase family; Region: Y_phosphatase3; pfam13350
695560005486	Tyrosine phosphatase family; Region: Y_phosphatase2; pfam03162
695560005487	Tyrosine phosphatase family C-terminal region; Region: Y_phosphatase3C; pfam13348
695560005488	Predicted flavoprotein [General function prediction only]; Region: COG0431
695560005489	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
695560005490	Predicted flavoprotein [General function prediction only]; Region: COG0431
695560005491	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
695560005492	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
695560005493	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
695560005494	WHG domain; Region: WHG; pfam13305
695560005495	Peptidase family C69; Region: Peptidase_C69; pfam03577
695560005496	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
695560005497	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
695560005498	Walker A/P-loop; other site
695560005499	ATP binding site [chemical binding]; other site
695560005500	Q-loop/lid; other site
695560005501	ABC transporter signature motif; other site
695560005502	Walker B; other site
695560005503	D-loop; other site
695560005504	H-loop/switch region; other site
695560005505	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
695560005506	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
695560005507	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
695560005508	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
695560005509	catalytic core [active]
695560005510	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
695560005511	Putative serine esterase (DUF676); Region: DUF676; pfam05057
695560005512	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
695560005513	hypothetical protein; Validated; Region: PRK02101
695560005514	HIT family: HIT (Histidine triad) proteins, named for a motif related to the sequence HxHxH/Qxx (x, a hydrophobic amino acid), are a superfamily of nucleotide hydrolases and transferases, which act on the alpha-phosphate of ribonucleotides. On the basis...; Region: HIT_like; cl00228
695560005515	nucleotide binding site/active site [active]
695560005516	HIT family signature motif; other site
695560005517	catalytic residue [active]
695560005518	Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229
695560005519	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
695560005520	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
695560005521	Probable transposase; Region: OrfB_IS605; pfam01385
695560005522	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
695560005523	Predicted membrane protein [Function unknown]; Region: COG2364
695560005524	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
695560005525	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
695560005526	putative substrate translocation pore; other site
695560005527	POT family; Region: PTR2; cl17359
695560005528	Peptidase family M1; Region: Peptidase_M1; pfam01433
695560005529	Peptidase M1 Aminopeptidase N family incudes tricorn interacting factor F3, Endoplasmic reticulum aminopeptidase 1 (ERAP1), Aminopeptidase Q (APQ); Region: M1_APN_2; cd09601
695560005530	Zn binding site [ion binding]; other site
695560005531	Domain of unknown function (DUF3358); Region: DUF3358; pfam11838
695560005532	potential frameshift: common BLAST hit: gi|268319421|ref|YP_003293077.1| ABC transporter ATPase and permease components
695560005533	drug efflux system protein MdtG; Provisional; Region: PRK09874
695560005534	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
695560005535	putative substrate translocation pore; other site
695560005536	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
695560005537	putative ADP-ribose binding site [chemical binding]; other site
695560005538	putative active site [active]
695560005539	Helix-turn-helix domain; Region: HTH_19; pfam12844
695560005540	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
695560005541	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
695560005542	Walker A/P-loop; other site
695560005543	ATP binding site [chemical binding]; other site
695560005544	Q-loop/lid; other site
695560005545	ABC transporter signature motif; other site
695560005546	Walker B; other site
695560005547	D-loop; other site
695560005548	H-loop/switch region; other site
695560005549	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
695560005550	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
695560005551	dimer interface [polypeptide binding]; other site
695560005552	conserved gate region; other site
695560005553	putative PBP binding loops; other site
695560005554	ABC-ATPase subunit interface; other site
695560005555	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
695560005556	dimer interface [polypeptide binding]; other site
695560005557	conserved gate region; other site
695560005558	ABC-ATPase subunit interface; other site
695560005559	Maltose-binding periplasmic proteins/domains [Carbohydrate transport and metabolism]; Region: MalE; COG2182
695560005560	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
695560005561	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
695560005562	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
695560005563	Walker A/P-loop; other site
695560005564	ATP binding site [chemical binding]; other site
695560005565	Q-loop/lid; other site
695560005566	ABC transporter signature motif; other site
695560005567	Walker B; other site
695560005568	D-loop; other site
695560005569	H-loop/switch region; other site
695560005570	TOBE domain; Region: TOBE_2; pfam08402
695560005571	beta-phosphoglucomutase; Region: bPGM; TIGR01990
695560005572	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
695560005573	motif II; other site
695560005574	maltose phosphorylase; Provisional; Region: PRK13807
695560005575	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
695560005576	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
695560005577	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
695560005578	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
695560005579	homodimer interface [polypeptide binding]; other site
695560005580	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
695560005581	active site
695560005582	homodimer interface [polypeptide binding]; other site
695560005583	catalytic site [active]
695560005584	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
695560005585	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
695560005586	Ca binding site [ion binding]; other site
695560005587	active site
695560005588	catalytic site [active]
695560005589	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
695560005590	propionate/acetate kinase; Provisional; Region: PRK12379
695560005591	Transcriptional regulators [Transcription]; Region: PurR; COG1609
695560005592	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
695560005593	DNA binding site [nucleotide binding]
695560005594	domain linker motif; other site
695560005595	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
695560005596	ligand binding site [chemical binding]; other site
695560005597	dimerization interface [polypeptide binding]; other site
695560005598	Tyrosine phosphatase family; Region: Y_phosphatase3; pfam13350
695560005599	Tyrosine phosphatase family C-terminal region; Region: Y_phosphatase3C; pfam13348
695560005600	glycerol kinase; Provisional; Region: glpK; PRK00047
695560005601	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
695560005602	N- and C-terminal domain interface [polypeptide binding]; other site
695560005603	active site
695560005604	MgATP binding site [chemical binding]; other site
695560005605	catalytic site [active]
695560005606	metal binding site [ion binding]; metal-binding site
695560005607	glycerol binding site [chemical binding]; other site
695560005608	homotetramer interface [polypeptide binding]; other site
695560005609	homodimer interface [polypeptide binding]; other site
695560005610	FBP binding site [chemical binding]; other site
695560005611	protein IIAGlc interface [polypeptide binding]; other site
695560005612	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
695560005613	dimer interface [polypeptide binding]; other site
695560005614	substrate binding site [chemical binding]; other site
695560005615	ATP binding site [chemical binding]; other site
695560005616	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
695560005617	AAA domain; Region: AAA_14; pfam13173
695560005618	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
695560005619	catalytic triad [active]
695560005620	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
695560005621	NlpC/P60 family; Region: NLPC_P60; pfam00877
695560005622	EamA-like transporter family; Region: EamA; pfam00892
695560005623	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
695560005624	EamA-like transporter family; Region: EamA; pfam00892
695560005625	EamA-like transporter family; Region: EamA; pfam00892
695560005626	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
695560005627	EamA-like transporter family; Region: EamA; pfam00892
695560005628	adenylosuccinate lyase; Provisional; Region: PRK07492
695560005629	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
695560005630	tetramer interface [polypeptide binding]; other site
695560005631	active site
695560005632	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
695560005633	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
695560005634	GDP-binding site [chemical binding]; other site
695560005635	ACT binding site; other site
695560005636	IMP binding site; other site
695560005637	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05458
695560005638	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
695560005639	active site
695560005640	Uncharacterized conserved protein [Function unknown]; Region: COG3589
695560005641	Bacterial protein of unknown function (DUF871); Region: DUF871; pfam05913
695560005642	asparagine synthetase A; Reviewed; Region: PRK06462
695560005643	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
695560005644	dimer interface [polypeptide binding]; other site
695560005645	active site
695560005646	Amino acid permease; Region: AA_permease_2; pfam13520
695560005647	Peptidase C26; Region: Peptidase_C26; pfam07722
695560005648	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
695560005649	catalytic triad [active]
695560005650	putative transport protein YifK; Provisional; Region: PRK10746
695560005651	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
695560005652	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
695560005653	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
695560005654	Catalytic site [active]
695560005655	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
695560005656	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
695560005657	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
695560005658	Walker A motif; other site
695560005659	ATP binding site [chemical binding]; other site
695560005660	Walker B motif; other site
695560005661	arginine finger; other site
695560005662	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
695560005663	Walker A motif; other site
695560005664	ATP binding site [chemical binding]; other site
695560005665	Walker B motif; other site
695560005666	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
695560005667	Alpha/beta hydrolase of unknown function (DUF915); Region: DUF915; pfam06028
695560005668	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
695560005669	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
695560005670	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
695560005671	Walker A/P-loop; other site
695560005672	ATP binding site [chemical binding]; other site
695560005673	Q-loop/lid; other site
695560005674	ABC transporter signature motif; other site
695560005675	Walker B; other site
695560005676	D-loop; other site
695560005677	H-loop/switch region; other site
695560005678	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
695560005679	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
695560005680	FtsX-like permease family; Region: FtsX; pfam02687
695560005681	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
695560005682	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
695560005683	FtsX-like permease family; Region: FtsX; pfam02687
695560005684	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
695560005685	Cpl-1 lysin (also known as Cpl-9 lysozyme / muramidase) is a bacterial cell wall endolysin encoded by the pneumococcal bacteriophage Cp-1, which cleaves the glycosidic N-acetylmuramoyl-(beta1,4)-N-acetylglucosamine bonds of the pneumococcal glycan chain; Region: GH25_Cpl1-like; cd06415
695560005686	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
695560005687	active site
695560005688	Bacterial surface layer protein; Region: SLAP; pfam03217
695560005689	Protein of unknown function (DUF975); Region: DUF975; cl10504
695560005690	YrhK-like protein; Region: YrhK; pfam14145
695560005691	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
695560005692	non-specific DNA binding site [nucleotide binding]; other site
695560005693	salt bridge; other site
695560005694	sequence-specific DNA binding site [nucleotide binding]; other site
695560005695	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
695560005696	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
695560005697	cobalt transport protein ATP-binding subunit; Region: cbiO; TIGR01166
695560005698	Walker A/P-loop; other site
695560005699	ATP binding site [chemical binding]; other site
695560005700	Q-loop/lid; other site
695560005701	ABC transporter signature motif; other site
695560005702	Walker B; other site
695560005703	D-loop; other site
695560005704	H-loop/switch region; other site
695560005705	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
695560005706	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
695560005707	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
695560005708	Walker A/P-loop; other site
695560005709	ATP binding site [chemical binding]; other site
695560005710	Q-loop/lid; other site
695560005711	ABC transporter signature motif; other site
695560005712	Walker B; other site
695560005713	D-loop; other site
695560005714	H-loop/switch region; other site
695560005715	Transposase, Mutator family; Region: Transposase_mut; pfam00872
695560005716	MULE transposase domain; Region: MULE; pfam10551
695560005717	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
695560005718	active site
695560005719	ATP binding site [chemical binding]; other site
695560005720	substrate binding site [chemical binding]; other site
695560005721	activation loop (A-loop); other site
695560005722	LanC-like proteins. LanC is the cyclase enzyme of the lanthionine synthetase. Lanthionine is a lantibiotic, a unique class of peptide antibiotics. They are ribosomally synthesized as a precursor peptide and then post-translationally modified to contain...; Region: LanC_like; cl04955
695560005723	active site
695560005724	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
695560005725	Beta-lactamase; Region: Beta-lactamase; pfam00144
695560005726	D-alanyl-lipoteichoic acid biosynthesis protein DltD; Region: LTA_DltD; TIGR04092
695560005727	DltD N-terminal region; Region: DltD_N; pfam04915
695560005728	DltD central region; Region: DltD_M; pfam04918
695560005729	DltD C-terminal region; Region: DltD_C; pfam04914
695560005730	D-alanine--poly(phosphoribitol) ligase subunit 2; Validated; Region: PRK05087
695560005731	D-alanyl-lipoteichoic acid biosynthesis protein DltB; Region: LTA_dltB; TIGR04091
695560005732	D-alanine--poly(phosphoribitol) ligase subunit 1; Provisional; Region: PRK04813
695560005733	D-alanine:D-alanyl carrier protein ligase (DltA); Region: DltA; cd05945
695560005734	acyl-activating enzyme (AAE) consensus motif; other site
695560005735	AMP binding site [chemical binding]; other site
695560005736	D-Ala-teichoic acid biosynthesis protein; Region: DUF3687; pfam12459
695560005737	FOG: CBS domain [General function prediction only]; Region: COG0517
695560005738	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_30; cd04643
695560005739	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
695560005740	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
695560005741	Soluble P-type ATPase [General function prediction only]; Region: COG4087
695560005742	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
695560005743	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
695560005744	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
695560005745	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
695560005746	Probable transposase; Region: OrfB_IS605; pfam01385
695560005747	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
695560005748	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
695560005749	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
695560005750	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
695560005751	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
695560005752	Walker A/P-loop; other site
695560005753	ATP binding site [chemical binding]; other site
695560005754	Q-loop/lid; other site
695560005755	ABC transporter signature motif; other site
695560005756	Walker B; other site
695560005757	D-loop; other site
695560005758	H-loop/switch region; other site
695560005759	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
695560005760	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
695560005761	non-specific DNA binding site [nucleotide binding]; other site
695560005762	salt bridge; other site
695560005763	sequence-specific DNA binding site [nucleotide binding]; other site
695560005764	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
695560005765	Bacteriophage peptidoglycan hydrolase; Region: Amidase_5; pfam05382
695560005766	CAAX protease self-immunity; Region: Abi; pfam02517
695560005767	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
695560005768	putative active site [active]
695560005769	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
695560005770	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
695560005771	Walker A/P-loop; other site
695560005772	ATP binding site [chemical binding]; other site
695560005773	Q-loop/lid; other site
695560005774	ABC transporter signature motif; other site
695560005775	Walker B; other site
695560005776	D-loop; other site
695560005777	H-loop/switch region; other site
695560005778	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
695560005779	FtsX-like permease family; Region: FtsX; pfam02687
695560005780	Predicted membrane protein [Function unknown]; Region: COG4684
695560005781	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
695560005782	Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein [General function prediction only]; Region: Med; COG1744
695560005783	Periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea; Region: PBP1_BmpA_PnrA_like; cd06354
695560005784	ligand binding site [chemical binding]; other site
695560005785	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
695560005786	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
695560005787	active site
695560005788	catalytic tetrad [active]
695560005789	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
695560005790	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
695560005791	active site
695560005792	trimer interface [polypeptide binding]; other site
695560005793	allosteric site; other site
695560005794	active site lid [active]
695560005795	hexamer (dimer of trimers) interface [polypeptide binding]; other site
695560005796	Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428
695560005797	Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1; Region: dNK; cd01673
695560005798	Substrate-binding site [chemical binding]; other site
695560005799	Substrate specificity [chemical binding]; other site
695560005800	Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428
695560005801	Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1; Region: dNK; cd01673
695560005802	Substrate-binding site [chemical binding]; other site
695560005803	Substrate specificity [chemical binding]; other site
695560005804	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
695560005805	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
695560005806	active site
695560005807	motif I; other site
695560005808	motif II; other site
695560005809	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
695560005810	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
695560005811	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
695560005812	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
695560005813	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
695560005814	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
695560005815	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
695560005816	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
695560005817	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
695560005818	Conjugative relaxosome accessory transposon protein; Region: TraH; cl05580
695560005819	YSIRK type signal peptide; Region: YSIRK_signal; cl04650
695560005820	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
695560005821	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
695560005822	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
695560005823	Transposase; Region: DDE_Tnp_ISL3; pfam01610
695560005824	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
695560005825	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
695560005826	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
695560005827	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
695560005828	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
695560005829	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
695560005830	peptide binding site [polypeptide binding]; other site
695560005831	CAAX protease self-immunity; Region: Abi; pfam02517
695560005832	copper transport repressor, CopY/TcrY family; Region: CopY_TcrY; TIGR02698
695560005833	Penicillinase repressor; Region: Pencillinase_R; pfam03965
695560005834	Cupredoxin-like domain; Region: Cupredoxin_1; pfam13473
695560005835	Cupredoxin-like domain; Region: Cupredoxin_1; pfam13473
695560005836	copper-(or silver)-translocating P-type ATPase; Region: ATPase-IB1_Cu; TIGR01511
695560005837	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
695560005838	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
695560005839	potential frameshift: common BLAST hit: gi|295693788|ref|YP_003602398.1| Membrane protein
695560005840	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
695560005841	global nitrogen regulator NtcA, cyanobacterial; Region: NtcA_cyano; TIGR03697
695560005842	ligand binding site [chemical binding]; other site
695560005843	flexible hinge region; other site
695560005844	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
695560005845	putative switch regulator; other site
695560005846	non-specific DNA interactions [nucleotide binding]; other site
695560005847	DNA binding site [nucleotide binding]
695560005848	sequence specific DNA binding site [nucleotide binding]; other site
695560005849	putative cAMP binding site [chemical binding]; other site
695560005850	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
695560005851	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
695560005852	Cl- selectivity filter; other site
695560005853	Cl- binding residues [ion binding]; other site
695560005854	pore gating glutamate residue; other site
695560005855	dimer interface [polypeptide binding]; other site
695560005856	H+/Cl- coupling transport residue; other site
695560005857	TrkA-C domain; Region: TrkA_C; pfam02080
695560005858	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
695560005859	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
695560005860	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
695560005861	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
695560005862	pyruvate oxidase; Region: pyruv_oxi_spxB; TIGR02720
695560005863	PYR/PP interface [polypeptide binding]; other site
695560005864	dimer interface [polypeptide binding]; other site
695560005865	tetramer interface [polypeptide binding]; other site
695560005866	TPP binding site [chemical binding]; other site
695560005867	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
695560005868	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
695560005869	TPP-binding site [chemical binding]; other site
695560005870	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
695560005871	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
695560005872	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
695560005873	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
695560005874	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
695560005875	trmE is a tRNA modification GTPase; Region: trmE; cd04164
695560005876	G1 box; other site
695560005877	GTP/Mg2+ binding site [chemical binding]; other site
695560005878	Switch I region; other site
695560005879	G2 box; other site
695560005880	Switch II region; other site
695560005881	G3 box; other site
695560005882	G4 box; other site
695560005883	G5 box; other site
695560005884	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
695560005885	Preprotein translocase subunit YidC [Intracellular trafficking and secretion]; Region: YidC; COG0706
695560005886	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
695560005887	ribonuclease P; Reviewed; Region: rnpA; PRK00499
695560005888	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
695560005889	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
695560005890	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
695560005891	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
695560005892	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
695560005893	Walker A/P-loop; other site
695560005894	Walker A/P-loop; other site
695560005895	ATP binding site [chemical binding]; other site
695560005896	ATP binding site [chemical binding]; other site
695560005897	Q-loop/lid; other site
695560005898	ABC transporter signature motif; other site
695560005899	Walker B; other site
695560005900	D-loop; other site
695560005901	H-loop/switch region; other site
695560005902	Integrase core domain; Region: rve; pfam00665
695560005903	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
695560005904	active site
695560005905	DNA binding site [nucleotide binding]
695560005906	Int/Topo IB signature motif; other site
695560005907	Domain of unknown function (DUF4379); Region: DUF4379; pfam14311
695560005908	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
695560005909	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
695560005910	Cupin domain; Region: Cupin_2; pfam07883
695560005911	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
695560005912	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
695560005913	nucleotide binding site [chemical binding]; other site
695560005914	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
695560005915	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; Region: MATE_yoeA_like; cd13138
695560005916	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_8; cd13134
695560005917	putative efflux protein, MATE family; Region: matE; TIGR00797
695560005918	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
695560005919	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
695560005920	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
695560005921	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
695560005922	P-loop; other site
695560005923	Magnesium ion binding site [ion binding]; other site
695560005924	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
695560005925	Magnesium ion binding site [ion binding]; other site
695560005926	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
695560005927	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
695560005928	Replication initiator protein A (RepA) N-terminus; Region: RepA_N; pfam06970
695560005929	PIF1-like helicase; Region: PIF1; pfam05970
695560005930	AAA domain; Region: AAA_30; pfam13604
695560005931	Family description; Region: UvrD_C_2; pfam13538
695560005932	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
695560005933	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
695560005934	This family is the oxydase domain of NRPS (non-ribosomal peptide synthetase) and other proteins that modify polypeptides by cyclizing a thioester to form a ring. These include epoB, part of the epothilone biosynthesis pathway; tubD, part of the tubulysin...; Region: mcbC-like_oxidoreductase; cd02142
695560005935	putative FMN binding site [chemical binding]; other site
695560005936	NADPH bind site [chemical binding]; other site
695560005937	YcaO-like family; Region: YcaO; pfam02624
695560005938	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
695560005939	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3421
695560005940	ATP binding site [chemical binding]; other site
695560005941	putative Mg++ binding site [ion binding]; other site
695560005942	Type III restriction/modification enzyme methylation subunit; Region: TypeIII_RM_meth; pfam12564
695560005943	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
695560005944	DNA methylase; Region: N6_N4_Mtase; pfam01555
695560005945	DNA methylase; Region: N6_N4_Mtase; pfam01555
695560005946	Protein of unknown function (DUF2922); Region: DUF2922; pfam11148
695560005947	YvrJ protein family; Region: YvrJ; pfam12841
695560005948	Phage integrase, N-terminal SAM-like domain; Region: Phage_integr_N; pfam02899
695560005949	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
695560005950	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
695560005951	active site
695560005952	catalytic residues [active]
695560005953	DNA binding site [nucleotide binding]
695560005954	Int/Topo IB signature motif; other site
695560005955	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
695560005956	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
695560005957	dimer interface [polypeptide binding]; other site
695560005958	ssDNA binding site [nucleotide binding]; other site
695560005959	tetramer (dimer of dimers) interface [polypeptide binding]; other site
695560005960	Replication initiation factor; Region: Rep_trans; pfam02486
695560005961	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
695560005962	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
695560005963	Bunyavirus glycoprotein G1; Region: Bunya_G1; pfam03557
695560005964	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
695560005965	DNA-methyltransferase (dcm); Region: dcm; TIGR00675
695560005966	cofactor binding site; other site
695560005967	DNA binding site [nucleotide binding]
695560005968	substrate interaction site [chemical binding]; other site
695560005969	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
695560005970	mismatch recognition site; other site
695560005971	additional DNA contacts [nucleotide binding]; other site
695560005972	active site
695560005973	zinc binding site [ion binding]; other site
695560005974	DNA intercalation site [nucleotide binding]; other site
695560005975	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
695560005976	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
695560005977	P-loop; other site
695560005978	Magnesium ion binding site [ion binding]; other site
695560005979	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
695560005980	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
695560005981	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
695560005982	active site
695560005983	Protein of unknown function (DUF2922); Region: DUF2922; pfam11148
695560005984	YvrJ protein family; Region: YvrJ; pfam12841
695560005985	Phage integrase, N-terminal SAM-like domain; Region: Phage_integr_N; pfam02899
695560005986	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
695560005987	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
695560005988	active site
695560005989	catalytic residues [active]
695560005990	DNA binding site [nucleotide binding]
695560005991	Int/Topo IB signature motif; other site
695560005992	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
695560005993	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
695560005994	dimer interface [polypeptide binding]; other site
695560005995	ssDNA binding site [nucleotide binding]; other site
695560005996	tetramer (dimer of dimers) interface [polypeptide binding]; other site
695560005997	potential frameshift: common BLAST hit: gi|269201747|ref|YP_003281016.1| replication initiation factor family protein