-- dump date   	20140619_123638
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
880633000001	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
880633000002	DnaA N-terminal domain; Region: DnaA_N; pfam11638
880633000003	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
880633000004	Walker A motif; other site
880633000005	ATP binding site [chemical binding]; other site
880633000006	Walker B motif; other site
880633000007	arginine finger; other site
880633000008	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
880633000009	DnaA box-binding interface [nucleotide binding]; other site
880633000010	DNA polymerase III subunit beta; Validated; Region: PRK05643
880633000011	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
880633000012	putative DNA binding surface [nucleotide binding]; other site
880633000013	dimer interface [polypeptide binding]; other site
880633000014	beta-clamp/clamp loader binding surface; other site
880633000015	beta-clamp/translesion DNA polymerase binding surface; other site
880633000016	S4 domain; Region: S4_2; pfam13275
880633000017	recombination protein F; Reviewed; Region: recF; PRK00064
880633000018	ATP-binding cassette domain of RecF; Region: ABC_RecF; cd03242
880633000019	Walker A/P-loop; other site
880633000020	ATP binding site [chemical binding]; other site
880633000021	Q-loop/lid; other site
880633000022	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
880633000023	ABC transporter signature motif; other site
880633000024	Walker B; other site
880633000025	D-loop; other site
880633000026	H-loop/switch region; other site
880633000027	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
880633000028	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
880633000029	Mg2+ binding site [ion binding]; other site
880633000030	G-X-G motif; other site
880633000031	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
880633000032	anchoring element; other site
880633000033	dimer interface [polypeptide binding]; other site
880633000034	ATP binding site [chemical binding]; other site
880633000035	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
880633000036	active site
880633000037	putative metal-binding site [ion binding]; other site
880633000038	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
880633000039	DNA gyrase subunit A; Validated; Region: PRK05560
880633000040	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
880633000041	CAP-like domain; other site
880633000042	active site
880633000043	primary dimer interface [polypeptide binding]; other site
880633000044	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
880633000045	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
880633000046	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
880633000047	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
880633000048	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
880633000049	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
880633000050	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
880633000051	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
880633000052	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
880633000053	dimer interface [polypeptide binding]; other site
880633000054	ssDNA binding site [nucleotide binding]; other site
880633000055	tetramer (dimer of dimers) interface [polypeptide binding]; other site
880633000056	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
880633000057	Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain [Signal transduction mechanisms]; Region: COG3887
880633000058	Class III nucleotidyl cyclases; Region: Nucleotidyl_cyc_III; cl11967
880633000059	DHH family; Region: DHH; pfam01368
880633000060	DHHA1 domain; Region: DHHA1; pfam02272
880633000061	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
880633000062	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
880633000063	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
880633000064	replicative DNA helicase; Region: DnaB; TIGR00665
880633000065	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
880633000066	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
880633000067	Walker A motif; other site
880633000068	ATP binding site [chemical binding]; other site
880633000069	Walker B motif; other site
880633000070	DNA binding loops [nucleotide binding]
880633000071	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; pfam12974
880633000072	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
880633000073	membrane-bound complex binding site; other site
880633000074	hinge residues; other site
880633000075	EDD domain protein, DegV family; Region: DegV; TIGR00762
880633000076	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
880633000077	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
880633000078	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
880633000079	nucleotide binding site [chemical binding]; other site
880633000080	potential frameshift: common BLAST hit: gi|336053313|ref|YP_004558005.1| putative integrase core domain-containing protein
880633000081	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
880633000082	Integrase core domain; Region: rve; pfam00665
880633000083	Uncharacterized protein family (UPF0236); Region: UPF0236; pfam06782
880633000084	Uncharacterized protein family (UPF0236); Region: UPF0236; pfam06782
880633000085	Predicted membrane protein [Function unknown]; Region: COG2261
880633000086	Protein of unknown function (DUF2974); Region: DUF2974; pfam11187
880633000087	MgtC family; Region: MgtC; pfam02308
880633000088	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
880633000089	Transposase, Mutator family; Region: Transposase_mut; pfam00872
880633000090	MULE transposase domain; Region: MULE; pfam10551
880633000091	Ubiquitin-like proteins; Region: UBQ; cl00155
880633000092	charged pocket; other site
880633000093	hydrophobic patch; other site
880633000094	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
880633000095	thiazole biosynthesis adenylyltransferase ThiF, E. coli subfamily; Region: adenyl_thiF; TIGR02356
880633000096	ATP binding site [chemical binding]; other site
880633000097	substrate interface [chemical binding]; other site
880633000098	potential frameshift: common BLAST hit: gi|296454078|ref|YP_003661221.1| major facilitator superfamily protein
880633000099	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
880633000100	Transposase; Region: DEDD_Tnp_IS110; pfam01548
880633000101	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
880633000102	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
880633000103	potential frameshift: common BLAST hit: gi|58336665|ref|YP_193250.1| replication protein
880633000104	potential frameshift: common BLAST hit: gi|58336814|ref|YP_193399.1| replication initiator protein
880633000105	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
880633000106	active site
880633000107	DNA binding site [nucleotide binding]
880633000108	Int/Topo IB signature motif; other site
880633000109	enolase; Provisional; Region: eno; PRK00077
880633000110	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
880633000111	dimer interface [polypeptide binding]; other site
880633000112	metal binding site [ion binding]; metal-binding site
880633000113	substrate binding pocket [chemical binding]; other site
880633000114	Protein of unknown function (DUF3278); Region: DUF3278; pfam11683
880633000115	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
880633000116	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
880633000117	non-specific DNA binding site [nucleotide binding]; other site
880633000118	salt bridge; other site
880633000119	sequence-specific DNA binding site [nucleotide binding]; other site
880633000120	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4619
880633000121	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
880633000122	Walker A/P-loop; other site
880633000123	ATP binding site [chemical binding]; other site
880633000124	Q-loop/lid; other site
880633000125	ABC transporter signature motif; other site
880633000126	Walker B; other site
880633000127	D-loop; other site
880633000128	H-loop/switch region; other site
880633000129	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG0390
880633000130	potential frameshift: common BLAST hit: gi|385812885|ref|YP_005849278.1| SIR2 family protein
880633000131	NAD-dependent protein deacetylases, SIR2 family [Transcription]; Region: SIR2; COG0846
880633000132	Restriction endonuclease; Region: Mrr_cat; pfam04471
880633000133	Peptidase family C69; Region: Peptidase_C69; cl17793
880633000134	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
880633000135	Probable transposase; Region: OrfB_IS605; pfam01385
880633000136	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
880633000137	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
880633000138	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
880633000139	Piccolo Zn-finger; Region: zf-piccolo; pfam05715
880633000140	Peptidase family C69; Region: Peptidase_C69; cl17793
880633000141	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
880633000142	Predicted membrane protein [Function unknown]; Region: COG4905
880633000143	Protein of unknown function (DUF1113); Region: DUF1113; pfam06541
880633000144	Cobalamin adenosyltransferase; Region: Cob_adeno_trans; pfam01923
880633000145	ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent; Region: RTPR; TIGR02505
880633000146	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
880633000147	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
880633000148	Isoamyl-acetate hydrolyzing esterase-like proteins. SGNH_hydrolase subfamily similar to the Saccharomyces cerevisiae IAH1. IAH1 may be the major esterase that hydrolyses isoamyl acetate in sake mash.  The SGNH-family of hydrolases is a diverse family of...; Region: Isoamyl_acetate_hydrolase_like; cd01838
880633000149	catalytic triad [active]
880633000150	oxyanion hole [active]
880633000151	active site
880633000152	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: PhnK; COG1101
880633000153	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
880633000154	Walker A/P-loop; other site
880633000155	ATP binding site [chemical binding]; other site
880633000156	Q-loop/lid; other site
880633000157	ABC transporter signature motif; other site
880633000158	Walker B; other site
880633000159	D-loop; other site
880633000160	H-loop/switch region; other site
880633000161	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cd06574
880633000162	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
880633000163	TM-ABC transporter signature motif; other site
880633000164	Type I periplasmic ligand-binding domain of uncharacterized ABC-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_uncharacterized_transporter; cd06325
880633000165	zinc binding site [ion binding]; other site
880633000166	putative ligand binding site [chemical binding]; other site
880633000167	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
880633000168	HAD superfamily (subfamily IA) hydrolase, TIGR02254; Region: YjjG/YfnB
880633000169	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
880633000170	active site
880633000171	motif I; other site
880633000172	motif II; other site
880633000173	Translation elongation factors (GTPases) [Translation, ribosomal structure and biogenesis]; Region: FusA; COG0480
880633000174	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
880633000175	G5 box; other site
880633000176	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
880633000177	Elongation Factor G-like domain IV. This family includes the translational elongation factor termed EF-2 (for Archaea and Eukarya) and EF-G (for Bacteria), ribosomal protection proteins that mediate tetracycline resistance and, an evolutionarily...; Region: EFG_like_IV; cl02789
880633000178	Tet_C: C-terminus of ribosomal protection proteins Tet(M) and Tet(O). This domain has homology to the C terminal domains of the elongation factors EF-G and EF-2. Tet(M) and Tet(O) catalyze the release of tetracycline (Tc) from the ribosome in a...; Region: Tet_C; cd03711
880633000179	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
880633000180	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
880633000181	active site
880633000182	motif I; other site
880633000183	motif II; other site
880633000184	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
880633000185	D-lactate dehydrogenase; Validated; Region: PRK08605
880633000186	D-Lactate dehydrogenase and D-2-Hydroxyisocaproic acid dehydrogenase (D-HicDH), NAD-binding and catalytic domains; Region: LDH; cd12186
880633000187	homodimer interface [polypeptide binding]; other site
880633000188	ligand binding site [chemical binding]; other site
880633000189	NAD binding site [chemical binding]; other site
880633000190	catalytic site [active]
880633000191	Fructosamine kinase; Region: Fructosamin_kin; cl17579
880633000192	Phosphotransferase enzyme family; Region: APH; pfam01636
880633000193	Human Ape1-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Ape1-like_AP-endo; cd09087
880633000194	active site
880633000195	putative catalytic site [active]
880633000196	DNA binding site [nucleotide binding]
880633000197	putative phosphate binding site [ion binding]; other site
880633000198	metal binding site A [ion binding]; metal-binding site
880633000199	AP binding site [nucleotide binding]; other site
880633000200	metal binding site B [ion binding]; metal-binding site
880633000201	potential frameshift: common BLAST hit: gi|385812913|ref|YP_005849306.1| APC family amino acid-polyamine-organocation transporter
880633000202	N-terminal putative catalytic domain of uncharacterized prokaryotic and archeal HKD family nucleases fused to a DEAD/DEAH box helicase domain; Region: PLDc_N_DEXD_b2; cd09204
880633000203	PLD-like domain; Region: PLDc_2; pfam13091
880633000204	putative homodimer interface [polypeptide binding]; other site
880633000205	putative active site [active]
880633000206	catalytic site [active]
880633000207	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
880633000208	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
880633000209	ATP binding site [chemical binding]; other site
880633000210	putative Mg++ binding site [ion binding]; other site
880633000211	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
880633000212	nucleotide binding region [chemical binding]; other site
880633000213	ATP-binding site [chemical binding]; other site
880633000214	Domain of unknown function (DUF3427); Region: DUF3427; pfam11907
880633000215	Beta-lactamase; Region: Beta-lactamase; pfam00144
880633000216	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
880633000217	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
880633000218	active site
880633000219	catalytic residues [active]
880633000220	metal binding site [ion binding]; metal-binding site
880633000221	Branched-chain amino acid transport protein; Region: Branch_AA_trans; cl00547
880633000222	potential frameshift: common BLAST hit: gi|325955775|ref|YP_004286385.1| transcriptional regulator
880633000223	Transcriptional regulator [Transcription]; Region: LysR; COG0583
880633000224	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
880633000225	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
880633000226	dimerization interface [polypeptide binding]; other site
880633000227	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
880633000228	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
880633000229	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
880633000230	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
880633000231	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
880633000232	putative acyl-acceptor binding pocket; other site
880633000233	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
880633000234	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
880633000235	Ligand binding site; other site
880633000236	metal-binding site
880633000237	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
880633000238	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
880633000239	Ligand binding site; other site
880633000240	metal-binding site
880633000241	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
880633000242	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
880633000243	active site
880633000244	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
880633000245	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cl17185
880633000246	putative acyl-acceptor binding pocket; other site
880633000247	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
880633000248	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
880633000249	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
880633000250	active site
880633000251	phosphorylation site [posttranslational modification]
880633000252	intermolecular recognition site; other site
880633000253	dimerization interface [polypeptide binding]; other site
880633000254	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
880633000255	DNA binding site [nucleotide binding]
880633000256	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: VicK; COG5002
880633000257	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
880633000258	dimerization interface [polypeptide binding]; other site
880633000259	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
880633000260	putative active site [active]
880633000261	heme pocket [chemical binding]; other site
880633000262	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
880633000263	dimer interface [polypeptide binding]; other site
880633000264	phosphorylation site [posttranslational modification]
880633000265	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
880633000266	ATP binding site [chemical binding]; other site
880633000267	Mg2+ binding site [ion binding]; other site
880633000268	G-X-G motif; other site
880633000269	YycH protein; Region: YycH; pfam07435
880633000270	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4863
880633000271	YycH protein; Region: YycI; pfam09648
880633000272	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
880633000273	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
880633000274	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
880633000275	protein binding site [polypeptide binding]; other site
880633000276	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
880633000277	Transposase; Region: DEDD_Tnp_IS110; pfam01548
880633000278	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
880633000279	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
880633000280	Transposase; Region: DEDD_Tnp_IS110; pfam01548
880633000281	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
880633000282	non-specific DNA binding site [nucleotide binding]; other site
880633000283	salt bridge; other site
880633000284	sequence-specific DNA binding site [nucleotide binding]; other site
880633000285	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
880633000286	Bacterial surface layer protein; Region: SLAP; pfam03217
880633000287	proline-specific peptidase, Bacillus coagulans-type subfamily; Region: pro_imino_pep_2; TIGR01250
880633000288	Cobalt transport protein; Region: CbiQ; cl00463
880633000289	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
880633000290	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
880633000291	Walker A/P-loop; other site
880633000292	ATP binding site [chemical binding]; other site
880633000293	Q-loop/lid; other site
880633000294	ABC transporter signature motif; other site
880633000295	Walker B; other site
880633000296	D-loop; other site
880633000297	H-loop/switch region; other site
880633000298	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
880633000299	Walker A/P-loop; other site
880633000300	ATP binding site [chemical binding]; other site
880633000301	ABC transporter; Region: ABC_tran; pfam00005
880633000302	Q-loop/lid; other site
880633000303	ABC transporter signature motif; other site
880633000304	Walker B; other site
880633000305	D-loop; other site
880633000306	H-loop/switch region; other site
880633000307	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
880633000308	Helix-turn-helix domain; Region: HTH_18; pfam12833
880633000309	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
880633000310	heat shock protein HtpX; Provisional; Region: PRK04897
880633000311	Uncharacterized conserved protein [Function unknown]; Region: LemA; COG1704
880633000312	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
880633000313	transmembrane helices; other site
880633000314	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
880633000315	Membrane domain of glycerophosphoryl diester phosphodiesterase; Region: GPDPase_memb; pfam10110
880633000316	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
880633000317	Glycerophosphodiester phosphodiesterase domain of uncharacterized bacterial glycerophosphodiester phosphodiesterases; Region: GDPD_memb_like; cd08579
880633000318	putative active site [active]
880633000319	catalytic site [active]
880633000320	putative metal binding site [ion binding]; other site
880633000321	Uncharacterized protein family (UPF0236); Region: UPF0236; pfam06782
880633000322	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
880633000323	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
880633000324	DXD motif; other site
880633000325	Glycosyl hydrolases family 8; Region: Glyco_hydro_8; cl01351
880633000326	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
880633000327	Zn2+ binding site [ion binding]; other site
880633000328	Mg2+ binding site [ion binding]; other site
880633000329	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
880633000330	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
880633000331	active site
880633000332	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
880633000333	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
880633000334	Walker A/P-loop; other site
880633000335	ATP binding site [chemical binding]; other site
880633000336	Q-loop/lid; other site
880633000337	ABC transporter signature motif; other site
880633000338	Walker B; other site
880633000339	D-loop; other site
880633000340	H-loop/switch region; other site
880633000341	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
880633000342	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
880633000343	substrate binding pocket [chemical binding]; other site
880633000344	membrane-bound complex binding site; other site
880633000345	hinge residues; other site
880633000346	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
880633000347	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
880633000348	dimer interface [polypeptide binding]; other site
880633000349	conserved gate region; other site
880633000350	putative PBP binding loops; other site
880633000351	ABC-ATPase subunit interface; other site
880633000352	Alkyladenine DNA glycosylase catalyzes the first step in base excision repair; Region: AAG; cd00540
880633000353	active site
880633000354	DNA binding site [nucleotide binding]
880633000355	Protein of unknown function, DUF488; Region: DUF488; cl01246
880633000356	integral membrane protein, YkoY family; Region: R_switched_YkoY; TIGR03716
880633000357	methylated-DNA--protein-cysteine methyltransferase; Provisional; Region: PRK00901
880633000358	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
880633000359	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
880633000360	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
880633000361	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
880633000362	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
880633000363	cardiolipin synthase; Region: bac_cardiolipin; TIGR04265
880633000364	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
880633000365	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
880633000366	putative active site [active]
880633000367	catalytic site [active]
880633000368	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
880633000369	putative active site [active]
880633000370	catalytic site [active]
880633000371	Alpha/beta hydrolase of unknown function (DUF915); Region: DUF915; pfam06028
880633000372	Caulimovirus viroplasmin; Region: Cauli_VI; pfam01693
880633000373	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
880633000374	RNA/DNA hybrid binding site [nucleotide binding]; other site
880633000375	active site
880633000376	Predicted secreted protein [Function unknown]; Region: COG4086
880633000377	Protein of unknown function (DUF1002); Region: DUF1002; pfam06207
880633000378	putative glycosyl transferase; Provisional; Region: PRK10073
880633000379	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
880633000380	active site
880633000381	alpha/beta hydrolase fold; Region: Abhydrolase_1; pfam00561
880633000382	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
880633000383	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
880633000384	NADH(P)-binding; Region: NAD_binding_10; pfam13460
880633000385	NAD(P) binding site [chemical binding]; other site
880633000386	active site
880633000387	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
880633000388	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
880633000389	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
880633000390	active site
880633000391	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
880633000392	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
880633000393	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
880633000394	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
880633000395	substrate binding pocket [chemical binding]; other site
880633000396	membrane-bound complex binding site; other site
880633000397	hinge residues; other site
880633000398	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
880633000399	dimer interface [polypeptide binding]; other site
880633000400	conserved gate region; other site
880633000401	putative PBP binding loops; other site
880633000402	ABC-ATPase subunit interface; other site
880633000403	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
880633000404	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
880633000405	Walker A/P-loop; other site
880633000406	ATP binding site [chemical binding]; other site
880633000407	Q-loop/lid; other site
880633000408	ABC transporter signature motif; other site
880633000409	Walker B; other site
880633000410	D-loop; other site
880633000411	H-loop/switch region; other site
880633000412	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
880633000413	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
880633000414	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
880633000415	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
880633000416	Bacterial protein of unknown function (DUF948); Region: DUF948; cl01972
880633000417	YibE/F-like protein; Region: YibE_F; pfam07907
880633000418	YibE/F-like protein; Region: YibE_F; pfam07907
880633000419	Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657
880633000420	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
880633000421	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
880633000422	The enzymes of glycosyl hydrolase family 31 (GH31) occur in prokaryotes, eukaryotes, and archaea with a wide range of hydrolytic activities, including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-xylosidase, 6-alpha-glucosyltransferase; Region: GH31; cl11402
880633000423	The enzymes of glycosyl hydrolase family 31 (GH31) occur in prokaryotes, eukaryotes, and archaea with a wide range of hydrolytic activities, including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-xylosidase, 6-alpha-glucosyltransferase; Region: GH31; cl11402
880633000424	active site
880633000425	catalytic site [active]
880633000426	The enzymes of glycosyl hydrolase family 31 (GH31) occur in prokaryotes, eukaryotes, and archaea with a wide range of hydrolytic activities, including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-xylosidase, 6-alpha-glucosyltransferase; Region: GH31; cl11402
880633000427	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
880633000428	Interdomain contacts; other site
880633000429	Cytokine receptor motif; other site
880633000430	Nucleoside 2-deoxyribosyltransferase; Region: Nuc_deoxyrib_tr; pfam05014
880633000431	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
880633000432	active site
880633000433	phosphorylation site [posttranslational modification]
880633000434	Tyrosine phosphatase family; Region: Y_phosphatase3; pfam13350
880633000435	Tyrosine phosphatase family C-terminal region; Region: Y_phosphatase3C; pfam13348
880633000436	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
880633000437	Ligand Binding Site [chemical binding]; other site
880633000438	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; pfam12974
880633000439	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
880633000440	membrane-bound complex binding site; other site
880633000441	ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: COG3638
880633000442	ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Region: ABC_PhnC_transporter; cd03256
880633000443	Walker A/P-loop; other site
880633000444	ATP binding site [chemical binding]; other site
880633000445	Q-loop/lid; other site
880633000446	ABC transporter signature motif; other site
880633000447	Walker B; other site
880633000448	D-loop; other site
880633000449	H-loop/switch region; other site
880633000450	phosphonate ABC transporter, permease protein PhnE; Region: PhnE; TIGR01097
880633000451	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
880633000452	dimer interface [polypeptide binding]; other site
880633000453	conserved gate region; other site
880633000454	putative PBP binding loops; other site
880633000455	ABC-ATPase subunit interface; other site
880633000456	phosphonate ABC transporter, permease protein PhnE; Region: PhnE; TIGR01097
880633000457	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
880633000458	dimer interface [polypeptide binding]; other site
880633000459	conserved gate region; other site
880633000460	putative PBP binding loops; other site
880633000461	ABC-ATPase subunit interface; other site
880633000462	potential frameshift: common BLAST hit: gi|385812992|ref|YP_005849385.1| DNA-3-methyladenine glycosylase I
880633000463	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
880633000464	active site
880633000465	metal binding site [ion binding]; metal-binding site
880633000466	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
880633000467	active site
880633000468	dimer interface [polypeptide binding]; other site
880633000469	Glutamine amidotransferase domain; Region: GATase_6; pfam13522
880633000470	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
880633000471	Ligand Binding Site [chemical binding]; other site
880633000472	Molecular Tunnel; other site
880633000473	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
880633000474	Predicted ATP-grasp enzyme [General function prediction only]; Region: COG3919
880633000475	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
880633000476	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
880633000477	ATP cone domain; Region: ATP-cone; pfam03477
880633000478	Class III ribonucleotide reductase; Region: RNR_III; cd01675
880633000479	effector binding site; other site
880633000480	active site
880633000481	Zn binding site [ion binding]; other site
880633000482	glycine loop; other site
880633000483	anaerobic ribonucleotide reductase-activating protein; Provisional; Region: nrdG; cl15804
880633000484	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
880633000485	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
880633000486	Domain of unknown function (DUF1858); Region: DUF1858; pfam08984
880633000487	Uncharacterized conserved protein [Function unknown]; Region: COG2461
880633000488	Family of unknown function (DUF438); Region: DUF438; pfam04282
880633000489	Hemerythrin HHE cation binding domain; Region: Hemerythrin; pfam01814
880633000490	Major Facilitator Superfamily; Region: MFS_1; pfam07690
880633000491	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
880633000492	putative substrate translocation pore; other site
880633000493	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
880633000494	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
880633000495	active site
880633000496	Zn binding site [ion binding]; other site
880633000497	Probable transposase; Region: OrfB_IS605; pfam01385
880633000498	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
880633000499	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
880633000500	Piccolo Zn-finger; Region: zf-piccolo; pfam05715
880633000501	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
880633000502	K+ potassium transporter; Region: K_trans; pfam02705
880633000503	Protein of unknown function (DUF2922); Region: DUF2922; pfam11148
880633000504	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
880633000505	Bacterial surface layer protein; Region: SLAP; pfam03217
880633000506	potential frameshift: common BLAST hit: gi|295692036|ref|YP_003600646.1| RNA polymerase sigma factor
880633000507	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; cl17361
880633000508	Bacterial surface layer protein; Region: SLAP; pfam03217
880633000509	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
880633000510	amidase catalytic site [active]
880633000511	Zn binding residues [ion binding]; other site
880633000512	substrate binding site [chemical binding]; other site
880633000513	Bacterial surface layer protein; Region: SLAP; pfam03217
880633000514	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
880633000515	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
880633000516	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
880633000517	TrkA-N domain; Region: TrkA_N; pfam02254
880633000518	TrkA-C domain; Region: TrkA_C; pfam02080
880633000519	potential frameshift: common BLAST hit: gi|161506780|ref|YP_001576734.1| Phage associated protein
880633000520	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
880633000521	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
880633000522	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
880633000523	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
880633000524	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
880633000525	Probable transposase; Region: OrfB_IS605; pfam01385
880633000526	Probable transposase; Region: OrfB_IS605; pfam01385
880633000527	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
880633000528	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
880633000529	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
880633000530	Piccolo Zn-finger; Region: zf-piccolo; pfam05715
880633000531	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
880633000532	catalytic core [active]
880633000533	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
880633000534	Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I:  Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from...; Region: Peptidase_C15; cd00501
880633000535	putative substrate binding pocket [chemical binding]; other site
880633000536	AC domain interface; other site
880633000537	catalytic triad [active]
880633000538	AB domain interface; other site
880633000539	interchain disulfide; other site
880633000540	potential frameshift: common BLAST hit: gi|161507702|ref|YP_001577658.1| transposase
880633000541	aldose 1-epimerase superfamily; Region: Aldose_epim; cl14648
880633000542	Cell envelope-related transcriptional attenuator domain; Region: LytR_cpsA_psr; cl00581
880633000543	Glycerol-3-phosphate acyltransferase; Region: G3P_acyltransf; cl00410
880633000544	Sulfatase; Region: Sulfatase; cl17466
880633000545	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
880633000546	Interdomain contacts; other site
880633000547	Cytokine receptor motif; other site
880633000548	tyrosyl-tRNA synthetase; Provisional; Region: PRK13354
880633000549	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
880633000550	active site
880633000551	HIGH motif; other site
880633000552	dimer interface [polypeptide binding]; other site
880633000553	KMSKS motif; other site
880633000554	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
880633000555	RNA binding surface [nucleotide binding]; other site
880633000556	Peptidase C1B subfamily (MEROPS database nomenclature); composed of eukaryotic bleomycin hydrolases (BH) and bacterial aminopeptidases C (pepC). The proteins of this subfamily contain a large insert relative to the C1A peptidase (papain) subfamily. BH is...; Region: Peptidase_C1B; cd00585
880633000557	trimer interface [polypeptide binding]; other site
880633000558	active site
880633000559	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
880633000560	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215
880633000561	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
880633000562	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
880633000563	peptide binding site [polypeptide binding]; other site
880633000564	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
880633000565	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
880633000566	peptide binding site [polypeptide binding]; other site
880633000567	inosine 5-monophosphate dehydrogenase; Validated; Region: PRK06843
880633000568	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
880633000569	active site
880633000570	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
880633000571	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
880633000572	dimer interface [polypeptide binding]; other site
880633000573	conserved gate region; other site
880633000574	putative PBP binding loops; other site
880633000575	ABC-ATPase subunit interface; other site
880633000576	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
880633000577	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
880633000578	dimer interface [polypeptide binding]; other site
880633000579	conserved gate region; other site
880633000580	putative PBP binding loops; other site
880633000581	ABC-ATPase subunit interface; other site
880633000582	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
880633000583	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
880633000584	Walker A/P-loop; other site
880633000585	ATP binding site [chemical binding]; other site
880633000586	Q-loop/lid; other site
880633000587	ABC transporter signature motif; other site
880633000588	Walker B; other site
880633000589	D-loop; other site
880633000590	H-loop/switch region; other site
880633000591	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
880633000592	ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; Region: AppF; COG4608
880633000593	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
880633000594	Walker A/P-loop; other site
880633000595	ATP binding site [chemical binding]; other site
880633000596	Q-loop/lid; other site
880633000597	ABC transporter signature motif; other site
880633000598	Walker B; other site
880633000599	D-loop; other site
880633000600	H-loop/switch region; other site
880633000601	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
880633000602	Peptidase C1B subfamily (MEROPS database nomenclature); composed of eukaryotic bleomycin hydrolases (BH) and bacterial aminopeptidases C (pepC). The proteins of this subfamily contain a large insert relative to the C1A peptidase (papain) subfamily. BH is...; Region: Peptidase_C1B; cd00585
880633000603	trimer interface [polypeptide binding]; other site
880633000604	active site
880633000605	Group of bacterial proteins containing an alpha crystallin domain (ACD) similar to Lactobacillus plantarum (Lp) small heat shock proteins (sHsp) HSP 18.5, HSP 18.55 and HSP 19.3. sHsps are molecular chaperones that suppress protein aggregation and...; Region: ACD_LpsHSP_like; cd06471
880633000606	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
880633000607	putative dimer interface [polypeptide binding]; other site
880633000608	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
880633000609	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
880633000610	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
880633000611	CAAX protease self-immunity; Region: Abi; pfam02517
880633000612	Uncharacterized ACR, COG2135; Region: DUF159; pfam02586
880633000613	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
880633000614	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
880633000615	active site
880633000616	HIGH motif; other site
880633000617	dimer interface [polypeptide binding]; other site
880633000618	KMSKS motif; other site
880633000619	Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286
880633000620	catalytic motif [active]
880633000621	Zn binding site [ion binding]; other site
880633000622	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
880633000623	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
880633000624	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
880633000625	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
880633000626	methionyl-tRNA synthetase; Reviewed; Region: PRK12267
880633000627	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
880633000628	active site
880633000629	HIGH motif; other site
880633000630	KMSKS motif; other site
880633000631	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
880633000632	tRNA binding surface [nucleotide binding]; other site
880633000633	anticodon binding site; other site
880633000634	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
880633000635	dimer interface [polypeptide binding]; other site
880633000636	putative tRNA-binding site [nucleotide binding]; other site
880633000637	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
880633000638	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
880633000639	active site
880633000640	TOPRIM_ RNase M5_like: The topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain found in Ribonuclease M5: (RNase M5) and other small primase-like proteins from bacteria and archaea.  RNase M5 catalyzes the maturation of 5S rRNA in low...; Region: TOPRIM_RNase_M5_like; cd01027
880633000641	ribonuclease M5; Region: 5S_RNA_mat_M5; TIGR00334
880633000642	putative active site [active]
880633000643	putative metal binding site [ion binding]; other site
880633000644	Domain of unknown function (DUF4093); Region: DUF4093; pfam13331
880633000645	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
880633000646	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
880633000647	potential frameshift: common BLAST hit: gi|161507702|ref|YP_001577658.1| transposase
880633000648	potential frameshift: common BLAST hit: gi|385813445|ref|YP_005849838.1| Transposase ISLhe15
880633000649	Protein of unknown function (DUF1021); Region: DUF1021; pfam06257
880633000650	pur operon repressor; Provisional; Region: PRK09213
880633000651	Bacterial purine repressor, N-terminal; Region: PuR_N; pfam09182
880633000652	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
880633000653	active site
880633000654	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14354
880633000655	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
880633000656	Substrate binding site; other site
880633000657	Mg++ binding site; other site
880633000658	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
880633000659	active site
880633000660	substrate binding site [chemical binding]; other site
880633000661	CoA binding site [chemical binding]; other site
880633000662	Bacterial surface layer protein; Region: SLAP; pfam03217
880633000663	Bacterial surface layer protein; Region: SLAP; pfam03217
880633000664	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
880633000665	Transposase; Region: DDE_Tnp_ISL3; pfam01610
880633000666	Bacterial surface layer protein; Region: SLAP; pfam03217
880633000667	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
880633000668	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
880633000669	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
880633000670	active site
880633000671	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
880633000672	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
880633000673	nucleotide binding site [chemical binding]; other site
880633000674	HD superfamily phosphohydrolases [General function prediction only]; Region: COG1078
880633000675	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
880633000676	Zn2+ binding site [ion binding]; other site
880633000677	Mg2+ binding site [ion binding]; other site
880633000678	Domain of unknown function (DUF1934); Region: DUF1934; pfam09148
880633000679	DNA-directed RNA polymerase delta subunit; Region: RNA_pol_delta; pfam05066
880633000680	CTP synthetase; Validated; Region: pyrG; PRK05380
880633000681	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
880633000682	Catalytic site [active]
880633000683	active site
880633000684	UTP binding site [chemical binding]; other site
880633000685	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
880633000686	active site
880633000687	putative oxyanion hole; other site
880633000688	catalytic triad [active]
880633000689	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
880633000690	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
880633000691	hinge; other site
880633000692	active site
880633000693	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
880633000694	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
880633000695	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
880633000696	motif II; other site
880633000697	Peptidase family C69; Region: Peptidase_C69; pfam03577
880633000698	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
880633000699	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
880633000700	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
880633000701	xanthine permease; Region: pbuX; TIGR03173
880633000702	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
880633000703	active site
880633000704	Uncharacterized protein family (UPF0236); Region: UPF0236; pfam06782
880633000705	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
880633000706	sequence-specific DNA binding site [nucleotide binding]; other site
880633000707	salt bridge; other site
880633000708	GMP synthase; Reviewed; Region: guaA; PRK00074
880633000709	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
880633000710	AMP/PPi binding site [chemical binding]; other site
880633000711	candidate oxyanion hole; other site
880633000712	catalytic triad [active]
880633000713	potential glutamine specificity residues [chemical binding]; other site
880633000714	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
880633000715	ATP Binding subdomain [chemical binding]; other site
880633000716	Ligand Binding sites [chemical binding]; other site
880633000717	Dimerization subdomain; other site
880633000718	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
880633000719	Probable transposase; Region: OrfB_IS605; pfam01385
880633000720	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
880633000721	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
880633000722	Piccolo Zn-finger; Region: zf-piccolo; pfam05715
880633000723	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
880633000724	potential frameshift: common BLAST hit: gi|336054615|ref|YP_004562902.1| transposase
880633000725	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
880633000726	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
880633000727	dimer interface [polypeptide binding]; other site
880633000728	active site
880633000729	glycine-pyridoxal phosphate binding site [chemical binding]; other site
880633000730	folate binding site [chemical binding]; other site
880633000731	Uncharacterized protein family (UPF0236); Region: UPF0236; pfam06782
880633000732	potential frameshift: common BLAST hit: gi|336055033|ref|YP_004563320.1| transposase
880633000733	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
880633000734	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
880633000735	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
880633000736	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
880633000737	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
880633000738	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
880633000739	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
880633000740	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
880633000741	DEAD-like helicases superfamily; Region: DEXDc; smart00487
880633000742	ATP binding site [chemical binding]; other site
880633000743	Mg++ binding site [ion binding]; other site
880633000744	motif III; other site
880633000745	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
880633000746	nucleotide binding region [chemical binding]; other site
880633000747	ATP-binding site [chemical binding]; other site
880633000748	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
880633000749	alanine racemase; Reviewed; Region: alr; PRK00053
880633000750	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
880633000751	active site
880633000752	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
880633000753	dimer interface [polypeptide binding]; other site
880633000754	substrate binding site [chemical binding]; other site
880633000755	catalytic residues [active]
880633000756	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
880633000757	FOG: CBS domain [General function prediction only]; Region: COG0517
880633000758	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
880633000759	L-lactate dehydrogenase; Reviewed; Region: ldh; PRK00066
880633000760	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
880633000761	tetramer (dimer of dimers) interface [polypeptide binding]; other site
880633000762	NAD binding site [chemical binding]; other site
880633000763	dimer interface [polypeptide binding]; other site
880633000764	substrate binding site [chemical binding]; other site
880633000765	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
880633000766	putative active site [active]
880633000767	catalytic residue [active]
880633000768	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
880633000769	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
880633000770	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
880633000771	ATP binding site [chemical binding]; other site
880633000772	putative Mg++ binding site [ion binding]; other site
880633000773	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
880633000774	nucleotide binding region [chemical binding]; other site
880633000775	ATP-binding site [chemical binding]; other site
880633000776	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
880633000777	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
880633000778	RNA binding surface [nucleotide binding]; other site
880633000779	Septum formation initiator; Region: DivIC; pfam04977
880633000780	Predicted RNA binding protein (contains ribosomal protein S1 domain) [Translation, ribosomal structure and biogenesis]; Region: VacB; COG1098
880633000781	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
880633000782	RNA binding site [nucleotide binding]; other site
880633000783	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
880633000784	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
880633000785	Ligand Binding Site [chemical binding]; other site
880633000786	FtsH Extracellular; Region: FtsH_ext; pfam06480
880633000787	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
880633000788	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
880633000789	Walker A motif; other site
880633000790	ATP binding site [chemical binding]; other site
880633000791	Walker B motif; other site
880633000792	arginine finger; other site
880633000793	Peptidase family M41; Region: Peptidase_M41; pfam01434
880633000794	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
880633000795	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
880633000796	dimerization interface [polypeptide binding]; other site
880633000797	domain crossover interface; other site
880633000798	redox-dependent activation switch; other site
880633000799	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
880633000800	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
880633000801	FMN binding site [chemical binding]; other site
880633000802	active site
880633000803	catalytic residues [active]
880633000804	substrate binding site [chemical binding]; other site
880633000805	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
880633000806	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
880633000807	dimer interface [polypeptide binding]; other site
880633000808	putative anticodon binding site; other site
880633000809	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
880633000810	motif 1; other site
880633000811	active site
880633000812	motif 2; other site
880633000813	motif 3; other site
880633000814	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
880633000815	GAF domain; Region: GAF_2; pfam13185
880633000816	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
880633000817	Clp amino terminal domain; Region: Clp_N; pfam02861
880633000818	Clp amino terminal domain; Region: Clp_N; pfam02861
880633000819	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
880633000820	Walker A motif; other site
880633000821	ATP binding site [chemical binding]; other site
880633000822	Walker B motif; other site
880633000823	arginine finger; other site
880633000824	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
880633000825	Walker A motif; other site
880633000826	ATP binding site [chemical binding]; other site
880633000827	Walker B motif; other site
880633000828	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
880633000829	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
880633000830	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
880633000831	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
880633000832	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
880633000833	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
880633000834	RPB1 interaction site [polypeptide binding]; other site
880633000835	RPB10 interaction site [polypeptide binding]; other site
880633000836	RPB11 interaction site [polypeptide binding]; other site
880633000837	RPB3 interaction site [polypeptide binding]; other site
880633000838	RPB12 interaction site [polypeptide binding]; other site
880633000839	DNA-directed RNA polymerase subunit beta'; Provisional; Region: PRK00566
880633000840	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
880633000841	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
880633000842	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
880633000843	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
880633000844	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
880633000845	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
880633000846	G-loop; other site
880633000847	DNA binding site [nucleotide binding]
880633000848	potential frameshift: common BLAST hit: gi|295693285|ref|YP_003601895.1| transposase
880633000849	potential frameshift: common BLAST hit: gi|385813433|ref|YP_005849826.1| Transposase domain protein
880633000850	potential frameshift: common BLAST hit: gi|315038223|ref|YP_004031791.1| transposase
880633000851	potential frameshift: common BLAST hit: gi|385813098|ref|YP_005849491.1| transposase
880633000852	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
880633000853	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
880633000854	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
880633000855	S17 interaction site [polypeptide binding]; other site
880633000856	S8 interaction site; other site
880633000857	16S rRNA interaction site [nucleotide binding]; other site
880633000858	streptomycin interaction site [chemical binding]; other site
880633000859	23S rRNA interaction site [nucleotide binding]; other site
880633000860	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
880633000861	30S ribosomal protein S7; Validated; Region: PRK05302
880633000862	elongation factor G; Reviewed; Region: PRK12739
880633000863	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
880633000864	G1 box; other site
880633000865	putative GEF interaction site [polypeptide binding]; other site
880633000866	GTP/Mg2+ binding site [chemical binding]; other site
880633000867	Switch I region; other site
880633000868	G2 box; other site
880633000869	G3 box; other site
880633000870	Switch II region; other site
880633000871	G4 box; other site
880633000872	G5 box; other site
880633000873	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
880633000874	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
880633000875	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
880633000876	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
880633000877	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
880633000878	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
880633000879	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
880633000880	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
880633000881	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
880633000882	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
880633000883	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
880633000884	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
880633000885	putative translocon binding site; other site
880633000886	protein-rRNA interface [nucleotide binding]; other site
880633000887	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
880633000888	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
880633000889	G-X-X-G motif; other site
880633000890	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
880633000891	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
880633000892	23S rRNA interface [nucleotide binding]; other site
880633000893	5S rRNA interface [nucleotide binding]; other site
880633000894	putative antibiotic binding site [chemical binding]; other site
880633000895	L25 interface [polypeptide binding]; other site
880633000896	L27 interface [polypeptide binding]; other site
880633000897	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
880633000898	23S rRNA interface [nucleotide binding]; other site
880633000899	putative translocon interaction site; other site
880633000900	signal recognition particle (SRP54) interaction site; other site
880633000901	L23 interface [polypeptide binding]; other site
880633000902	trigger factor interaction site; other site
880633000903	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
880633000904	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
880633000905	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
880633000906	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
880633000907	RNA binding site [nucleotide binding]; other site
880633000908	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
880633000909	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
880633000910	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
880633000911	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08061
880633000912	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
880633000913	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
880633000914	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
880633000915	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
880633000916	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
880633000917	23S rRNA interface [nucleotide binding]; other site
880633000918	L21e interface [polypeptide binding]; other site
880633000919	5S rRNA interface [nucleotide binding]; other site
880633000920	L27 interface [polypeptide binding]; other site
880633000921	L5 interface [polypeptide binding]; other site
880633000922	ribosomal protein S5, bacterial/organelle type; Region: rpsE_bact; TIGR01021
880633000923	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
880633000924	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
880633000925	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
880633000926	23S rRNA binding site [nucleotide binding]; other site
880633000927	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
880633000928	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
880633000929	SecY translocase; Region: SecY; pfam00344
880633000930	adenylate kinase; Reviewed; Region: adk; PRK00279
880633000931	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
880633000932	AMP-binding site [chemical binding]; other site
880633000933	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
880633000934	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
880633000935	rRNA binding site [nucleotide binding]; other site
880633000936	predicted 30S ribosome binding site; other site
880633000937	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
880633000938	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
880633000939	30S ribosomal protein S13; Region: bact_S13; TIGR03631
880633000940	30S ribosomal protein S11; Validated; Region: PRK05309
880633000941	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
880633000942	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
880633000943	alphaNTD homodimer interface [polypeptide binding]; other site
880633000944	alphaNTD - beta interaction site [polypeptide binding]; other site
880633000945	alphaNTD - beta' interaction site [polypeptide binding]; other site
880633000946	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
880633000947	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
880633000948	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13640
880633000949	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
880633000950	Walker A/P-loop; other site
880633000951	ATP binding site [chemical binding]; other site
880633000952	Q-loop/lid; other site
880633000953	ABC transporter signature motif; other site
880633000954	Walker B; other site
880633000955	D-loop; other site
880633000956	H-loop/switch region; other site
880633000957	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13641
880633000958	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
880633000959	Walker A/P-loop; other site
880633000960	ATP binding site [chemical binding]; other site
880633000961	Q-loop/lid; other site
880633000962	ABC transporter signature motif; other site
880633000963	Walker B; other site
880633000964	D-loop; other site
880633000965	H-loop/switch region; other site
880633000966	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
880633000967	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
880633000968	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
880633000969	dimerization interface 3.5A [polypeptide binding]; other site
880633000970	active site
880633000971	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
880633000972	23S rRNA interface [nucleotide binding]; other site
880633000973	L3 interface [polypeptide binding]; other site
880633000974	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
880633000975	Protein of unknown function (DUF805); Region: DUF805; pfam05656
880633000976	DJ-1 family protein; Region: not_thiJ; TIGR01383
880633000977	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
880633000978	conserved cys residue [active]
880633000979	HAD superfamily (subfamily IA) hydrolase, TIGR02254; Region: YjjG/YfnB
880633000980	hypothetical protein; Provisional; Region: PRK10621
880633000981	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
880633000982	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
880633000983	catalytic core [active]
880633000984	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
880633000985	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
880633000986	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
880633000987	catalytic core [active]
880633000988	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
880633000989	AAA domain; Region: AAA_33; pfam13671
880633000990	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
880633000991	Probable transposase; Region: OrfB_IS605; pfam01385
880633000992	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
880633000993	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
880633000994	Piccolo Zn-finger; Region: zf-piccolo; pfam05715
880633000995	magnesium-transporting ATPase; Provisional; Region: PRK15122
880633000996	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
880633000997	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
880633000998	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
880633000999	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
880633001000	motif II; other site
880633001001	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
880633001002	RhaT L-rhamnose-proton symporter family protein; Region: RhaT; TIGR00776
880633001003	Peptidase C1B subfamily (MEROPS database nomenclature); composed of eukaryotic bleomycin hydrolases (BH) and bacterial aminopeptidases C (pepC). The proteins of this subfamily contain a large insert relative to the C1A peptidase (papain) subfamily. BH is...; Region: Peptidase_C1B; cd00585
880633001004	trimer interface [polypeptide binding]; other site
880633001005	active site
880633001006	G bulge; other site
880633001007	Probable transposase; Region: OrfB_IS605; pfam01385
880633001008	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
880633001009	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
880633001010	Piccolo Zn-finger; Region: zf-piccolo; pfam05715
880633001011	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
880633001012	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
880633001013	trimer interface [polypeptide binding]; other site
880633001014	active site
880633001015	DNA repair protein RadA; Provisional; Region: PRK11823
880633001016	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
880633001017	Walker A motif/ATP binding site; other site
880633001018	ATP binding site [chemical binding]; other site
880633001019	Walker B motif; other site
880633001020	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
880633001021	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
880633001022	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
880633001023	active site
880633001024	HIGH motif; other site
880633001025	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
880633001026	active site
880633001027	KMSKS motif; other site
880633001028	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
880633001029	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
880633001030	active site
880633001031	HIGH motif; other site
880633001032	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
880633001033	KMSKS motif; other site
880633001034	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
880633001035	tRNA binding surface [nucleotide binding]; other site
880633001036	anticodon binding site; other site
880633001037	Ribonuclease III family protein [Replication, recombination, and    repair]; Region: COG1939
880633001038	active site
880633001039	metal binding site [ion binding]; metal-binding site
880633001040	dimerization interface [polypeptide binding]; other site
880633001041	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
880633001042	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
880633001043	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
880633001044	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
880633001045	gluconate kinase, FGGY type; Region: gntK_FGGY; TIGR01314
880633001046	Gluconate kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_GntK; cd07770
880633001047	N- and C-terminal domain interface [polypeptide binding]; other site
880633001048	active site
880633001049	catalytic site [active]
880633001050	metal binding site [ion binding]; metal-binding site
880633001051	carbohydrate binding site [chemical binding]; other site
880633001052	ATP binding site [chemical binding]; other site
880633001053	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK12315
880633001054	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
880633001055	TPP-binding site; other site
880633001056	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
880633001057	PYR/PP interface [polypeptide binding]; other site
880633001058	dimer interface [polypeptide binding]; other site
880633001059	TPP binding site [chemical binding]; other site
880633001060	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
880633001061	50S ribosomal protein L33; Validated; Region: rpmG; PRK00504
880633001062	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK07597
880633001063	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
880633001064	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
880633001065	putative homodimer interface [polypeptide binding]; other site
880633001066	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
880633001067	heterodimer interface [polypeptide binding]; other site
880633001068	homodimer interface [polypeptide binding]; other site
880633001069	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
880633001070	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
880633001071	23S rRNA interface [nucleotide binding]; other site
880633001072	L7/L12 interface [polypeptide binding]; other site
880633001073	putative thiostrepton binding site; other site
880633001074	L25 interface [polypeptide binding]; other site
880633001075	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
880633001076	mRNA/rRNA interface [nucleotide binding]; other site
880633001077	PBP superfamily domain; Region: PBP_like_2; cl17296
880633001078	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573
880633001079	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
880633001080	dimer interface [polypeptide binding]; other site
880633001081	conserved gate region; other site
880633001082	putative PBP binding loops; other site
880633001083	ABC-ATPase subunit interface; other site
880633001084	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstA; COG0581
880633001085	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
880633001086	dimer interface [polypeptide binding]; other site
880633001087	conserved gate region; other site
880633001088	putative PBP binding loops; other site
880633001089	ABC-ATPase subunit interface; other site
880633001090	phosphate transporter ATP-binding protein; Provisional; Region: PRK14237
880633001091	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
880633001092	Walker A/P-loop; other site
880633001093	ATP binding site [chemical binding]; other site
880633001094	Q-loop/lid; other site
880633001095	ABC transporter signature motif; other site
880633001096	Walker B; other site
880633001097	D-loop; other site
880633001098	H-loop/switch region; other site
880633001099	phosphate ABC transporter ATP-binding protein; Provisional; Region: PRK14251
880633001100	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
880633001101	Walker A/P-loop; other site
880633001102	ATP binding site [chemical binding]; other site
880633001103	Q-loop/lid; other site
880633001104	ABC transporter signature motif; other site
880633001105	Walker B; other site
880633001106	D-loop; other site
880633001107	H-loop/switch region; other site
880633001108	phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135
880633001109	PhoU domain; Region: PhoU; pfam01895
880633001110	PhoU domain; Region: PhoU; pfam01895
880633001111	potential frameshift: common BLAST hit: gi|385816957|ref|YP_005853347.1| receptor
880633001112	potential frameshift: common BLAST hit: gi|336053577|ref|YP_004561864.1| receptor
880633001113	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
880633001114	23S rRNA interface [nucleotide binding]; other site
880633001115	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
880633001116	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
880633001117	core dimer interface [polypeptide binding]; other site
880633001118	peripheral dimer interface [polypeptide binding]; other site
880633001119	L10 interface [polypeptide binding]; other site
880633001120	L11 interface [polypeptide binding]; other site
880633001121	putative EF-Tu interaction site [polypeptide binding]; other site
880633001122	putative EF-G interaction site [polypeptide binding]; other site
880633001123	potential frameshift: common BLAST hit: gi|295692234|ref|YP_003600844.1| k channel
880633001124	Methyltransferase domain; Region: Methyltransf_31; pfam13847
880633001125	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
880633001126	S-adenosylmethionine binding site [chemical binding]; other site
880633001127	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
880633001128	nucleoside/Zn binding site; other site
880633001129	dimer interface [polypeptide binding]; other site
880633001130	catalytic motif [active]
880633001131	DNA polymerase III subunits gamma and tau; Validated; Region: PRK05563
880633001132	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
880633001133	Walker A motif; other site
880633001134	ATP binding site [chemical binding]; other site
880633001135	Walker B motif; other site
880633001136	hypothetical protein; Validated; Region: PRK00153
880633001137	recombination protein RecR; Reviewed; Region: recR; PRK00076
880633001138	RecR protein; Region: RecR; pfam02132
880633001139	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
880633001140	putative active site [active]
880633001141	putative metal-binding site [ion binding]; other site
880633001142	tetramer interface [polypeptide binding]; other site
880633001143	Protein of unknown function (DUF2508); Region: DUF2508; pfam10704
880633001144	potential frameshift: common BLAST hit: gi|385813182|ref|YP_005849575.1| thymidylate kinase
880633001145	Protein of unknown function (DUF970); Region: DUF970; cl17525
880633001146	DNA polymerase III, delta subunit; Region: DNA_pol3_delta2; pfam13177
880633001147	DNA polymerase III subunit delta'; Validated; Region: PRK08485
880633001148	DNA replication intiation control protein YabA; Reviewed; Region: PRK13169
880633001149	Predicted methyltransferases [General function prediction only]; Region: COG0313
880633001150	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
880633001151	putative SAM binding site [chemical binding]; other site
880633001152	putative homodimer interface [polypeptide binding]; other site
880633001153	Acyl-ACP thioesterase; Region: Acyl-ACP_TE; pfam01643
880633001154	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
880633001155	active site
880633001156	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
880633001157	active site 2 [active]
880633001158	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
880633001159	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
880633001160	Glycoprotease family; Region: Peptidase_M22; pfam00814
880633001161	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
880633001162	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
880633001163	Coenzyme A binding pocket [chemical binding]; other site
880633001164	UGMP family protein; Validated; Region: PRK09604
880633001165	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
880633001166	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
880633001167	intersubunit interface [polypeptide binding]; other site
880633001168	active site
880633001169	catalytic residue [active]
880633001170	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
880633001171	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
880633001172	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
880633001173	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
880633001174	DNA-binding site [nucleotide binding]; DNA binding site
880633001175	UTRA domain; Region: UTRA; pfam07702
880633001176	Toxin ToxN, type III toxin-antitoxin system; Region: ToxN_toxin; pfam13958
880633001177	potential frameshift: common BLAST hit: gi|385813445|ref|YP_005849838.1| Transposase ISLhe15
880633001178	potential frameshift: common BLAST hit: gi|385816980|ref|YP_005853370.1| bile acid-inducible operon protein
880633001179	potential frameshift: common BLAST hit: gi|325956104|ref|YP_004286714.1| bile acid-inducible operon protein
880633001180	T-complex protein 11; Region: Tcp11; pfam05794
880633001181	CoA-transferase family III; Region: CoA_transf_3; pfam02515
880633001182	potential frameshift: common BLAST hit: gi|58336733|ref|YP_193318.1| oxalyl-CoA decarboxylase
880633001183	potential frameshift: common BLAST hit: gi|336053291|ref|YP_004557983.1| transposase
880633001184	potential frameshift: common BLAST hit: gi|336053291|ref|YP_004557983.1| transposase
880633001185	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
880633001186	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
880633001187	Transposase; Region: DEDD_Tnp_IS110; pfam01548
880633001188	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
880633001189	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
880633001190	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
880633001191	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
880633001192	ABC transporter; Region: ABC_tran_2; pfam12848
880633001193	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
880633001194	ABC transporter; Region: ABC_tran_2; pfam12848
880633001195	redox-sensing transcriptional repressor Rex; Provisional; Region: PRK05472
880633001196	Putative DNA-binding protein N-terminus; Region: Put_DNA-bind_N; pfam06971
880633001197	CoA binding domain; Region: CoA_binding; pfam02629
880633001198	LytTr DNA-binding domain; Region: LytTR; smart00850
880633001199	Uncharacterized protein family (UPF0182); Region: UPF0182; pfam03699
880633001200	Transcriptional regulators [Transcription]; Region: PurR; COG1609
880633001201	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
880633001202	DNA binding site [nucleotide binding]
880633001203	domain linker motif; other site
880633001204	Ligand binding domain of the lacI-like transcription regulator from a novel metal-reducing bacterium Alkaliphilus Metalliredigens (strain Qymf) and its close homologs; Region: PBP1_Qymf_like; cd06291
880633001205	dimerization interface [polypeptide binding]; other site
880633001206	ligand binding site [chemical binding]; other site
880633001207	sodium binding site [ion binding]; other site
880633001208	sucrose-6-phosphate hydrolase; Region: scrB_fam; TIGR01322
880633001209	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
880633001210	substrate binding [chemical binding]; other site
880633001211	active site
880633001212	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
880633001213	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
880633001214	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
880633001215	active site turn [active]
880633001216	phosphorylation site [posttranslational modification]
880633001217	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
880633001218	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
880633001219	HPr interaction site; other site
880633001220	glycerol kinase (GK) interaction site [polypeptide binding]; other site
880633001221	active site
880633001222	phosphorylation site [posttranslational modification]
880633001223	Transposase, Mutator family; Region: Transposase_mut; pfam00872
880633001224	MULE transposase domain; Region: MULE; pfam10551
880633001225	potential frameshift: common BLAST hit: gi|161507702|ref|YP_001577658.1| transposase
880633001226	potential frameshift: common BLAST hit: gi|385813445|ref|YP_005849838.1| Transposase ISLhe15
880633001227	flavocytochrome c; Region: flavo_cyto_c; TIGR01813
880633001228	potential frameshift: common BLAST hit: gi|104774648|ref|YP_619628.1| LysR family transcriptional regulator
880633001229	Abi-like protein; Region: Abi_2; pfam07751
880633001230	Abi-like protein; Region: Abi_2; cl01988
880633001231	L-aminoadipate-semialdehyde dehydrogenase; Region: alpha_am_amid; TIGR03443
880633001232	Abi-like protein; Region: Abi_2; pfam07751
880633001233	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
880633001234	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
880633001235	Peptidase S8 family domain in Streptococcal C5a peptidases; Region: Peptidases_S8_C5a_Peptidase; cd07475
880633001236	catalytic triad [active]
880633001237	putative active site [active]
880633001238	Fn3-like domain (DUF1034); Region: DUF1034; pfam06280
880633001239	Bacterial surface layer protein; Region: SLAP; pfam03217
880633001240	Bacterial surface layer protein; Region: SLAP; pfam03217
880633001241	potential frameshift: common BLAST hit: gi|161507038|ref|YP_001576992.1| transposase
880633001242	potential frameshift: common BLAST hit: gi|336054613|ref|YP_004562900.1| transposase
880633001243	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
880633001244	Int/Topo IB signature motif; other site
880633001245	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
880633001246	oligomerisation interface [polypeptide binding]; other site
880633001247	mobile loop; other site
880633001248	roof hairpin; other site
880633001249	chaperonin GroL; Region: GroEL; TIGR02348
880633001250	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
880633001251	ring oligomerisation interface [polypeptide binding]; other site
880633001252	ATP/Mg binding site [chemical binding]; other site
880633001253	stacking interactions; other site
880633001254	hinge regions; other site
880633001255	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
880633001256	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
880633001257	potential frameshift: common BLAST hit: gi|385826331|ref|YP_005862673.1| two-component system response regulator
880633001258	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
880633001259	Histidine kinase; Region: HisKA_3; pfam07730
880633001260	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
880633001261	potential frameshift: common BLAST hit: gi|385814378|ref|YP_005850771.1| Transposase, IS30 family
880633001262	potential frameshift: common BLAST hit: gi|385826329|ref|YP_005862671.1| putative ABC transporter
880633001263	Transposase, Mutator family; Region: Transposase_mut; pfam00872
880633001264	MULE transposase domain; Region: MULE; pfam10551
880633001265	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
880633001266	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
880633001267	active pocket/dimerization site; other site
880633001268	active site
880633001269	phosphorylation site [posttranslational modification]
880633001270	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cl00021
880633001271	active site
880633001272	phosphorylation site [posttranslational modification]
880633001273	PTS system sorbose-specific iic component; Region: EII-Sor; cl01506
880633001274	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
880633001275	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
880633001276	MutS domain I; Region: MutS_I; pfam01624
880633001277	MutS domain II; Region: MutS_II; pfam05188
880633001278	MutS domain III; Region: MutS_III; pfam05192
880633001279	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
880633001280	Walker A/P-loop; other site
880633001281	ATP binding site [chemical binding]; other site
880633001282	Q-loop/lid; other site
880633001283	ABC transporter signature motif; other site
880633001284	Walker B; other site
880633001285	D-loop; other site
880633001286	H-loop/switch region; other site
880633001287	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
880633001288	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
880633001289	ATP binding site [chemical binding]; other site
880633001290	Mg2+ binding site [ion binding]; other site
880633001291	G-X-G motif; other site
880633001292	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
880633001293	ATP binding site [chemical binding]; other site
880633001294	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
880633001295	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
880633001296	RuvA N terminal domain; Region: RuvA_N; pfam01330
880633001297	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
880633001298	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
880633001299	Walker A motif; other site
880633001300	ATP binding site [chemical binding]; other site
880633001301	Walker B motif; other site
880633001302	arginine finger; other site
880633001303	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
880633001304	Preprotein translocase subunit; Region: YajC; pfam02699
880633001305	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
880633001306	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
880633001307	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
880633001308	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
880633001309	active site
880633001310	DNA polymerase IV; Validated; Region: PRK02406
880633001311	DNA binding site [nucleotide binding]
880633001312	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
880633001313	DHH family; Region: DHH; pfam01368
880633001314	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
880633001315	DEAD-like helicases superfamily; Region: DEXDc; smart00487
880633001316	ATP binding site [chemical binding]; other site
880633001317	putative Mg++ binding site [ion binding]; other site
880633001318	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
880633001319	nucleotide binding region [chemical binding]; other site
880633001320	ATP-binding site [chemical binding]; other site
880633001321	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
880633001322	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
880633001323	motif 1; other site
880633001324	active site
880633001325	motif 2; other site
880633001326	motif 3; other site
880633001327	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
880633001328	DHHA1 domain; Region: DHHA1; pfam02272
880633001329	hypothetical protein; Provisional; Region: PRK05473
880633001330	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
880633001331	hypothetical protein; Provisional; Region: PRK13678
880633001332	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
880633001333	MutS domain III; Region: MutS_III; pfam05192
880633001334	ATP-binding cassette domain of MutS2; Region: ABC_MutS2; cd03280
880633001335	Walker A/P-loop; other site
880633001336	ATP binding site [chemical binding]; other site
880633001337	Q-loop/lid; other site
880633001338	ABC transporter signature motif; other site
880633001339	Walker B; other site
880633001340	D-loop; other site
880633001341	H-loop/switch region; other site
880633001342	Smr domain; Region: Smr; pfam01713
880633001343	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
880633001344	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
880633001345	catalytic residues [active]
880633001346	large-conductance mechanosensitive channel; Provisional; Region: mscL; PRK13952
880633001347	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
880633001348	Protein of unknown function (DUF2507); Region: DUF2507; pfam10702
880633001349	glutamate racemase; Provisional; Region: PRK00865
880633001350	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
880633001351	active site
880633001352	dimerization interface [polypeptide binding]; other site
880633001353	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
880633001354	Mechanosensitive ion channel; Region: MS_channel; pfam00924
880633001355	Bacterial protein of unknown function (DUF948); Region: DUF948; pfam06103
880633001356	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
880633001357	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
880633001358	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
880633001359	active site
880633001360	catabolite control protein A; Region: ccpA; TIGR01481
880633001361	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
880633001362	DNA binding site [nucleotide binding]
880633001363	domain linker motif; other site
880633001364	Ligand-binding domain of the catabolite control protein A (CcpA), which functions as the major transcriptional regulator of carbon catabolite repression/regulation; Region: PBP1_CcpA_like; cd06298
880633001365	dimerization interface [polypeptide binding]; other site
880633001366	effector binding site; other site
880633001367	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
880633001368	Glycerophosphodiester phosphodiesterase domain as found in prokaryota and eukaryota, and similar proteins; Region: GDPD; cd08556
880633001369	active site
880633001370	catalytic site [active]
880633001371	metal binding site [ion binding]; metal-binding site
880633001372	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
880633001373	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
880633001374	active site
880633001375	metal binding site [ion binding]; metal-binding site
880633001376	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
880633001377	Protein of unknown function (DUF1027); Region: DUF1027; cl09961
880633001378	HAD-superfamily subfamily IIA hydrolase, TIGR01457; Region: HAD-SF-IIA-hyp2
880633001379	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
880633001380	active site
880633001381	motif I; other site
880633001382	motif II; other site
880633001383	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
880633001384	Protein of unknown function (DUF1461); Region: DUF1461; pfam07314
880633001385	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
880633001386	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
880633001387	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
880633001388	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
880633001389	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
880633001390	potential frameshift: common BLAST hit: gi|161507702|ref|YP_001577658.1| transposase
880633001391	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
880633001392	This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1; Region: GT1_UGDG_like; cd03817
880633001393	putative ADP-binding pocket [chemical binding]; other site
880633001394	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
880633001395	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
880633001396	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
880633001397	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
880633001398	Sulfatase; Region: Sulfatase; pfam00884
880633001399	preprotein translocase subunit SecG; Reviewed; Region: secG; PRK06870
880633001400	ribonuclease R; Region: RNase_R; TIGR02063
880633001401	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
880633001402	RNB domain; Region: RNB; pfam00773
880633001403	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
880633001404	RNA binding site [nucleotide binding]; other site
880633001405	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
880633001406	SmpB-tmRNA interface; other site
880633001407	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
880633001408	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
880633001409	intersubunit interface [polypeptide binding]; other site
880633001410	potential protein location (hypothetical protein R0052_02690 [Lactobacillus helveticus R0052]) that overlaps RNA (tRNA-V)
880633001411	S-adenosylmethionine synthetase; Validated; Region: PRK05250
880633001412	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
880633001413	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
880633001414	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
880633001415	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
880633001416	Major Facilitator Superfamily; Region: MFS_1; pfam07690
880633001417	putative substrate translocation pore; other site
880633001418	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
880633001419	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
880633001420	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
880633001421	substrate binding pocket [chemical binding]; other site
880633001422	chain length determination region; other site
880633001423	substrate-Mg2+ binding site; other site
880633001424	catalytic residues [active]
880633001425	aspartate-rich region 1; other site
880633001426	active site lid residues [active]
880633001427	aspartate-rich region 2; other site
880633001428	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
880633001429	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
880633001430	active site
880633001431	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
880633001432	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
880633001433	HIGH motif; other site
880633001434	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
880633001435	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
880633001436	active site
880633001437	KMSKS motif; other site
880633001438	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
880633001439	tRNA binding surface [nucleotide binding]; other site
880633001440	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
880633001441	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
880633001442	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK14481
880633001443	Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Region: DAK1; COG2376
880633001444	DAK2 domain; Region: Dak2; cl03685
880633001445	Cupin domain; Region: Cupin_2; cl17218
880633001446	MucBP domain; Region: MucBP; pfam06458
880633001447	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
880633001448	catalytic residues [active]
880633001449	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
880633001450	dimerization interface [polypeptide binding]; other site
880633001451	putative DNA binding site [nucleotide binding]; other site
880633001452	putative Zn2+ binding site [ion binding]; other site
880633001453	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
880633001454	active site residue [active]
880633001455	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
880633001456	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
880633001457	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
880633001458	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
880633001459	DsbA family, FrnE subfamily; FrnE is a DsbA-like protein containing a CXXC motif. It is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the aromatic antibiotics frenolicin and nanaomycins; Region: DsbA_FrnE; cd03024
880633001460	Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FrnE; COG2761
880633001461	Uncharacterized protein family (UPF0236); Region: UPF0236; pfam06782
880633001462	Uncharacterized protein family (UPF0236); Region: UPF0236; pfam06782
880633001463	sugar phosphate phosphatase; Provisional; Region: PRK10513
880633001464	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
880633001465	active site
880633001466	motif I; other site
880633001467	motif II; other site
880633001468	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
880633001469	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
880633001470	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
880633001471	Piccolo Zn-finger; Region: zf-piccolo; pfam05715
880633001472	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
880633001473	Probable transposase; Region: OrfB_IS605; pfam01385
880633001474	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
880633001475	potential frameshift: common BLAST hit: gi|385813291|ref|YP_005849684.1| phosphatidylserine decarboxylase
880633001476	PspC domain; Region: PspC; pfam04024
880633001477	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
880633001478	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
880633001479	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
880633001480	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
880633001481	putative substrate binding site [chemical binding]; other site
880633001482	putative ATP binding site [chemical binding]; other site
880633001483	Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376
880633001484	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
880633001485	Predicted transcriptional regulators [Transcription]; Region: COG1695
880633001486	Transcriptional regulator PadR-like family; Region: PadR; cl17335
880633001487	Virulence activator alpha C-term; Region: Vir_act_alpha_C; pfam10400
880633001488	Phenolic acid decarboxylase (PAD); Region: PA_decarbox; cl01382
880633001489	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
880633001490	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
880633001491	arginyl-tRNA synthetase; Reviewed; Region: PRK12451
880633001492	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
880633001493	active site
880633001494	HIGH motif; other site
880633001495	KMSK motif region; other site
880633001496	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
880633001497	tRNA binding surface [nucleotide binding]; other site
880633001498	anticodon binding site; other site
880633001499	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
880633001500	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
880633001501	intersubunit interface [polypeptide binding]; other site
880633001502	active site
880633001503	zinc binding site [ion binding]; other site
880633001504	Na+ binding site [ion binding]; other site
880633001505	potential frameshift: common BLAST hit: gi|385813302|ref|YP_005849695.1| MutT/NUDIX family protein
880633001506	WbqC-like protein family; Region: WbqC; pfam08889
880633001507	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4586
880633001508	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
880633001509	Walker A/P-loop; other site
880633001510	ATP binding site [chemical binding]; other site
880633001511	Q-loop/lid; other site
880633001512	ABC transporter signature motif; other site
880633001513	Walker B; other site
880633001514	D-loop; other site
880633001515	H-loop/switch region; other site
880633001516	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
880633001517	potential frameshift: common BLAST hit: gi|385824975|ref|YP_005861317.1| putative transposase
880633001518	ABC-2 family transporter protein; Region: ABC2_membrane_6; cl01496
880633001519	ABC-2 family transporter protein; Region: ABC2_membrane_6; cl01496
880633001520	potential frameshift: common BLAST hit: gi|336054373|ref|YP_004562660.1| transposase
880633001521	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
880633001522	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
880633001523	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
880633001524	ligand binding site [chemical binding]; other site
880633001525	flexible hinge region; other site
880633001526	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
880633001527	putative switch regulator; other site
880633001528	non-specific DNA interactions [nucleotide binding]; other site
880633001529	DNA binding site [nucleotide binding]
880633001530	sequence specific DNA binding site [nucleotide binding]; other site
880633001531	putative cAMP binding site [chemical binding]; other site
880633001532	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
880633001533	potential frameshift: common BLAST hit: gi|385818136|ref|YP_005854526.1| Permease of the major facilitator superfamily protein
880633001534	Domain of unknown function (DUF1836); Region: DUF1836; pfam08876
880633001535	EDD domain protein, DegV family; Region: DegV; TIGR00762
880633001536	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
880633001537	Transposase, Mutator family; Region: Transposase_mut; pfam00872
880633001538	MULE transposase domain; Region: MULE; pfam10551
880633001539	Transposase, Mutator family; Region: Transposase_mut; pfam00872
880633001540	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
880633001541	Probable transposase; Region: OrfB_IS605; pfam01385
880633001542	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
880633001543	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
880633001544	Piccolo Zn-finger; Region: zf-piccolo; pfam05715
880633001545	triphosphoribosyl-dephospho-CoA synthase; Validated; Region: PRK01237
880633001546	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
880633001547	beta-galactosidase; Region: BGL; TIGR03356
880633001548	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
880633001549	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
880633001550	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
880633001551	putative active site [active]
880633001552	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
880633001553	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
880633001554	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
880633001555	amphipathic channel; other site
880633001556	Asn-Pro-Ala signature motifs; other site
880633001557	potential frameshift: common BLAST hit: gi|325956122|ref|YP_004286732.1| MgtC family protein
880633001558	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
880633001559	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
880633001560	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
880633001561	active site
880633001562	Transglycosylase; Region: Transgly; pfam00912
880633001563	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
880633001564	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
880633001565	hypothetical protein; Provisional; Region: PRK13676
880633001566	DNA repair exonuclease [DNA replication, recombination, and repair]; Region: SbcD; COG0420
880633001567	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
880633001568	active site
880633001569	metal binding site [ion binding]; metal-binding site
880633001570	DNA binding site [nucleotide binding]
880633001571	P-loop containing region of AAA domain; Region: AAA_29; cl17516
880633001572	AAA domain; Region: AAA_23; pfam13476
880633001573	3'-5' exoribonuclease YhaM; Provisional; Region: PRK13480
880633001574	YhaM_OBF_like: A subfamily of OB folds similar to that found in Bacillus subtilis YhaM and Staphylococcus aureus cmp-binding factor-1 (SaCBF1). Both these proteins are 3'-to-5'exoribonucleases. YhaM requires Mn2+ or Co2+ for activity and is...; Region: YhaM_OBF_like; cd04492
880633001575	generic binding surface I; other site
880633001576	generic binding surface II; other site
880633001577	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
880633001578	Zn2+ binding site [ion binding]; other site
880633001579	Mg2+ binding site [ion binding]; other site
880633001580	PAS domain; Region: PAS_10; pfam13596
880633001581	peptidylprolyl isomerase; Provisional; Region: prsA; PRK04405
880633001582	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
880633001583	YtxH-like protein; Region: YtxH; cl02079
880633001584	HINT (histidine triad nucleotide-binding protein) subgroup: Members of this CD belong to the superfamily of histidine triad hydrolases that act on alpha-phosphate of ribonucleotides. This subgroup includes members from all three forms of cellular life; Region: HINT_subgroup; cd01277
880633001585	HIT family signature motif; other site
880633001586	catalytic residue [active]
880633001587	Plasmid maintenance system killer protein; Region: Plasmid_killer; cl01422
880633001588	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
880633001589	non-specific DNA binding site [nucleotide binding]; other site
880633001590	salt bridge; other site
880633001591	sequence-specific DNA binding site [nucleotide binding]; other site
880633001592	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
880633001593	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
880633001594	Walker A/P-loop; other site
880633001595	ATP binding site [chemical binding]; other site
880633001596	Q-loop/lid; other site
880633001597	ABC transporter signature motif; other site
880633001598	Walker B; other site
880633001599	D-loop; other site
880633001600	H-loop/switch region; other site
880633001601	Bacterial ABC transporter protein EcsB; Region: EcsB; pfam05975
880633001602	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
880633001603	S-adenosylmethionine binding site [chemical binding]; other site
880633001604	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
880633001605	catalytic residues [active]
880633001606	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
880633001607	putative tRNA-binding site [nucleotide binding]; other site
880633001608	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
880633001609	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
880633001610	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
880633001611	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
880633001612	amino-acid N-acetyltransferase; Region: PLN02825
880633001613	potential frameshift: common BLAST hit: gi|161507881|ref|YP_001577845.1| aminopeptidase N
880633001614	potential frameshift: common BLAST hit: gi|161507881|ref|YP_001577845.1| aminopeptidase N
880633001615	RelB antitoxin; Region: RelB; cl01171
880633001616	HflC protein; Region: hflC; TIGR01932
880633001617	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
880633001618	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
880633001619	formate--tetrahydrofolate ligase; Provisional; Region: PRK13505
880633001620	Formyltetrahydrofolate synthetase (FTHFS) catalyzes the ATP-dependent activation of formate ion via its addition to the N10 position of tetrahydrofolate. FTHFS is a highly expressed key enzyme in both the Wood-Ljungdahl pathway of autotrophic CO2...; Region: FTHFS; cd00477
880633001621	Potassium binding sites [ion binding]; other site
880633001622	Cesium cation binding sites [ion binding]; other site
880633001623	AIR carboxylase; Region: AIRC; pfam00731
880633001624	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
880633001625	ATP-grasp domain; Region: ATP-grasp; pfam02222
880633001626	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
880633001627	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
880633001628	ATP binding site [chemical binding]; other site
880633001629	active site
880633001630	substrate binding site [chemical binding]; other site
880633001631	Phosphoribosylformylglycinamidine (FGAM) synthase; Region: PurS; pfam02700
880633001632	phosphoribosylformylglycinamidine synthase I; Provisional; Region: PRK03619
880633001633	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
880633001634	putative active site [active]
880633001635	catalytic triad [active]
880633001636	phosphoribosylformylglycinamidine synthase II; Provisional; Region: PRK01213
880633001637	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
880633001638	dimerization interface [polypeptide binding]; other site
880633001639	ATP binding site [chemical binding]; other site
880633001640	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
880633001641	dimerization interface [polypeptide binding]; other site
880633001642	ATP binding site [chemical binding]; other site
880633001643	amidophosphoribosyltransferase; Provisional; Region: PRK07272
880633001644	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
880633001645	active site
880633001646	tetramer interface [polypeptide binding]; other site
880633001647	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
880633001648	active site
880633001649	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
880633001650	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
880633001651	dimerization interface [polypeptide binding]; other site
880633001652	putative ATP binding site [chemical binding]; other site
880633001653	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
880633001654	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
880633001655	active site
880633001656	substrate binding site [chemical binding]; other site
880633001657	cosubstrate binding site; other site
880633001658	catalytic site [active]
880633001659	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
880633001660	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
880633001661	purine monophosphate binding site [chemical binding]; other site
880633001662	dimer interface [polypeptide binding]; other site
880633001663	putative catalytic residues [active]
880633001664	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
880633001665	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
880633001666	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
880633001667	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
880633001668	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
880633001669	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
880633001670	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
880633001671	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
880633001672	CRISPR-associated helicase Cas3; Region: cas3_core; TIGR01587
880633001673	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I-C; cd09651
880633001674	CRISPR-associated protein (Cas_Cas5); Region: Cas_Cas5d; pfam09704
880633001675	CRISPR/Cas system-associated protein Cas8c; Region: Cas8c_I-C; cl12004
880633001676	CRISPR/Cas system-associated RAMP superfamily protein Cas7; Region: Cas7_I-C; cl01465
880633001677	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cl00641
880633001678	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-II-III; cl00656
880633001679	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I_II_III; cd09725
880633001680	DNA polymerase I; Provisional; Region: PRK05755
880633001681	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
880633001682	active site
880633001683	metal binding site 1 [ion binding]; metal-binding site
880633001684	putative 5' ssDNA interaction site; other site
880633001685	metal binding site 3; metal-binding site
880633001686	metal binding site 2 [ion binding]; metal-binding site
880633001687	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
880633001688	putative DNA binding site [nucleotide binding]; other site
880633001689	putative metal binding site [ion binding]; other site
880633001690	inactive DEDDy 3'-5' exonuclease domain of Bacillus stearothermophilus DNA polymerase I and similar family-A DNA polymerases; Region: DNA_polA_I_Bacillus_like_exo; cd06140
880633001691	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
880633001692	active site
880633001693	DNA binding site [nucleotide binding]
880633001694	catalytic site [active]
880633001695	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
880633001696	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
880633001697	DNA binding site [nucleotide binding]
880633001698	catalytic residue [active]
880633001699	H2TH interface [polypeptide binding]; other site
880633001700	putative catalytic residues [active]
880633001701	turnover-facilitating residue; other site
880633001702	intercalation triad [nucleotide binding]; other site
880633001703	8OG recognition residue [nucleotide binding]; other site
880633001704	putative reading head residues; other site
880633001705	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
880633001706	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
880633001707	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
880633001708	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
880633001709	CoA-binding site [chemical binding]; other site
880633001710	ATP-binding [chemical binding]; other site
880633001711	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
880633001712	ATP cone domain; Region: ATP-cone; pfam03477
880633001713	Replication initiation/membrane attachment protein [DNA replication, recombination, and repair]; Region: DnaB; COG3611
880633001714	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
880633001715	primosomal protein DnaI; Reviewed; Region: PRK08939
880633001716	Primosomal protein DnaI N-terminus; Region: DnaI_N; pfam07319
880633001717	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
880633001718	Walker A motif; other site
880633001719	ATP binding site [chemical binding]; other site
880633001720	Walker B motif; other site
880633001721	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
880633001722	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
880633001723	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
880633001724	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
880633001725	active site
880633001726	dimer interface [polypeptide binding]; other site
880633001727	motif 1; other site
880633001728	motif 2; other site
880633001729	motif 3; other site
880633001730	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
880633001731	anticodon binding site; other site
880633001732	Uncharacterized conserved protein [Function unknown]; Region: COG3603
880633001733	Family description; Region: ACT_7; pfam13840
880633001734	Domain of unknown function (DUF389); Region: DUF389; pfam04087
880633001735	potential frameshift: common BLAST hit: gi|385818086|ref|YP_005854476.1| arylsulfate sulfotransferase
880633001736	potential frameshift: common BLAST hit: gi|385818086|ref|YP_005854476.1| arylsulfate sulfotransferase
880633001737	potential frameshift: common BLAST hit: gi|385818086|ref|YP_005854476.1| arylsulfate sulfotransferase
880633001738	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
880633001739	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
880633001740	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
880633001741	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
880633001742	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
880633001743	23S rRNA binding site [nucleotide binding]; other site
880633001744	L21 binding site [polypeptide binding]; other site
880633001745	L13 binding site [polypeptide binding]; other site
880633001746	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668; Region: YqeG_hyp_ppase
880633001747	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
880633001748	active site
880633001749	motif I; other site
880633001750	motif II; other site
880633001751	GTPase YqeH; Provisional; Region: PRK13796
880633001752	Circularly permuted YqeH GTPase; Region: YqeH; cd01855
880633001753	GTP/Mg2+ binding site [chemical binding]; other site
880633001754	G4 box; other site
880633001755	G5 box; other site
880633001756	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
880633001757	G1 box; other site
880633001758	G1 box; other site
880633001759	GTP/Mg2+ binding site [chemical binding]; other site
880633001760	G2 box; other site
880633001761	Switch I region; other site
880633001762	G2 box; other site
880633001763	Switch I region; other site
880633001764	G3 box; other site
880633001765	G3 box; other site
880633001766	Switch II region; other site
880633001767	Switch II region; other site
880633001768	G4 box; other site
880633001769	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
880633001770	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
880633001771	active site
880633001772	(T/H)XGH motif; other site
880633001773	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
880633001774	Zn2+ binding site [ion binding]; other site
880633001775	Mg2+ binding site [ion binding]; other site
880633001776	iojap-like ribosome-associated protein; Region: iojap_ybeB; TIGR00090
880633001777	hypothetical protein; Provisional; Region: PRK13670
880633001778	HIGH Nucleotidyl Transferase; Region: HIGH_NTase1; cl17673
880633001779	Uncharacterized ACR, COG1399; Region: DUF177; cl00616
880633001780	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
880633001781	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
880633001782	active site
880633001783	phosphorylation site [posttranslational modification]
880633001784	intermolecular recognition site; other site
880633001785	dimerization interface [polypeptide binding]; other site
880633001786	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
880633001787	DNA binding site [nucleotide binding]
880633001788	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
880633001789	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
880633001790	dimerization interface [polypeptide binding]; other site
880633001791	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
880633001792	dimer interface [polypeptide binding]; other site
880633001793	phosphorylation site [posttranslational modification]
880633001794	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
880633001795	ATP binding site [chemical binding]; other site
880633001796	Mg2+ binding site [ion binding]; other site
880633001797	G-X-G motif; other site
880633001798	YbaK-like.  The YbaK family of deacylase domains includes the INS amino acid-editing domain of  the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting homologs, YbaK, ProX, and PrdX. The primary function of INS is to hydrolyze...; Region: YbaK_like; cl00022
880633001799	putative deacylase active site [active]
880633001800	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
880633001801	Acylphosphatase; Region: Acylphosphatase; pfam00708
880633001802	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
880633001803	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
880633001804	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
880633001805	Predicted transcriptional regulators [Transcription]; Region: COG1733
880633001806	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
880633001807	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
880633001808	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
880633001809	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
880633001810	dimer interface [polypeptide binding]; other site
880633001811	motif 1; other site
880633001812	active site
880633001813	motif 2; other site
880633001814	motif 3; other site
880633001815	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
880633001816	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
880633001817	putative tRNA-binding site [nucleotide binding]; other site
880633001818	B3/4 domain; Region: B3_4; pfam03483
880633001819	tRNA synthetase B5 domain; Region: B5; smart00874
880633001820	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
880633001821	dimer interface [polypeptide binding]; other site
880633001822	motif 1; other site
880633001823	motif 3; other site
880633001824	motif 2; other site
880633001825	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
880633001826	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
880633001827	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
880633001828	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
880633001829	NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195
880633001830	Malate/lactate dehydrogenases [Energy production and conversion]; Region: Mdh; COG0039
880633001831	NAD(P) binding site [chemical binding]; other site
880633001832	LDH/MDH dimer interface [polypeptide binding]; other site
880633001833	substrate binding site [chemical binding]; other site
880633001834	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
880633001835	non-specific DNA binding site [nucleotide binding]; other site
880633001836	salt bridge; other site
880633001837	sequence-specific DNA binding site [nucleotide binding]; other site
880633001838	potential frameshift: common BLAST hit: gi|385813103|ref|YP_005849496.1| DNA integrase
880633001839	potential frameshift: common BLAST hit: gi|385813771|ref|YP_005850164.1| DNA integrase
880633001840	potential frameshift: common BLAST hit: gi|385825850|ref|YP_005862192.1| glycerate kinase
880633001841	PAS domain; Region: PAS_10; pfam13596
880633001842	Formate/nitrite transporter; Region: Form_Nir_trans; pfam01226
880633001843	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
880633001844	FAD binding domain; Region: FAD_binding_4; pfam01565
880633001845	Isochorismatase family; Region: Isochorismatase; pfam00857
880633001846	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
880633001847	catalytic triad [active]
880633001848	conserved cis-peptide bond; other site
880633001849	nicotinate phosphoribosyltransferase; Validated; Region: PRK09243
880633001850	Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction...; Region: NAPRTase_A; cd01570
880633001851	active site
880633001852	ADP-ribose pyrophosphatase [Nucleotide transport and metabolism]; Region: COG1051
880633001853	nudix motif; other site
880633001854	Uncharacterized conserved protein [General function prediction only]; Region: COG4111
880633001855	potential frameshift: common BLAST hit: gi|385814209|ref|YP_005850602.1| transposase
880633001856	potential frameshift: common BLAST hit: gi|385813975|ref|YP_005850368.1| transposase
880633001857	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
880633001858	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
880633001859	nucleotide binding site [chemical binding]; other site
880633001860	potential frameshift: common BLAST hit: gi|385813420|ref|YP_005849813.1| Putative ABC transporter
880633001861	potential frameshift: common BLAST hit: gi|385813420|ref|YP_005849813.1| Putative ABC transporter
880633001862	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
880633001863	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
880633001864	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
880633001865	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
880633001866	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
880633001867	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
880633001868	Rhomboid family; Region: Rhomboid; pfam01694
880633001869	Bacterial protein of unknown function (DUF910); Region: DUF910; pfam06014
880633001870	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
880633001871	active site residue [active]
880633001872	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
880633001873	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
880633001874	potential frameshift: common BLAST hit: gi|336053792|ref|YP_004562079.1| aluminum (al2+) resistance protein
880633001875	potential frameshift: common BLAST hit: gi|336053792|ref|YP_004562079.1| aluminum (al2+) resistance protein
880633001876	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
880633001877	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
880633001878	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
880633001879	potential frameshift: common BLAST hit: gi|385813433|ref|YP_005849826.1| Transposase domain protein
880633001880	potential frameshift: common BLAST hit: gi|385813433|ref|YP_005849826.1| Transposase domain protein
880633001881	potential frameshift: common BLAST hit: gi|58337981|ref|YP_194566.1| transposase
880633001882	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
880633001883	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
880633001884	NAD binding site [chemical binding]; other site
880633001885	homodimer interface [polypeptide binding]; other site
880633001886	active site
880633001887	substrate binding site [chemical binding]; other site
880633001888	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
880633001889	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
880633001890	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
880633001891	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
880633001892	Transcriptional regulators [Transcription]; Region: PurR; COG1609
880633001893	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
880633001894	DNA binding site [nucleotide binding]
880633001895	Ligand-binding domain of DNA transcription repressor GalR which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalR; cd01544
880633001896	putative dimerization interface [polypeptide binding]; other site
880633001897	putative ligand binding site [chemical binding]; other site
880633001898	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
880633001899	potential frameshift: common BLAST hit: gi|385826225|ref|YP_005862567.1| lactose permease
880633001900	potential frameshift: common BLAST hit: gi|385813439|ref|YP_005849832.1| Putative phosphotransferase enzyme IIA component
880633001901	potential frameshift: common BLAST hit: gi|58337730|ref|YP_194315.1| lactose permease
880633001902	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
880633001903	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
880633001904	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
880633001905	HPr interaction site; other site
880633001906	glycerol kinase (GK) interaction site [polypeptide binding]; other site
880633001907	active site
880633001908	phosphorylation site [posttranslational modification]
880633001909	potential frameshift: common BLAST hit: gi|336053806|ref|YP_004562093.1| beta-galactosidase
880633001910	Uncharacterized protein family (UPF0236); Region: UPF0236; pfam06782
880633001911	potential frameshift: common BLAST hit: gi|385813445|ref|YP_005849838.1| Transposase ISLhe15
880633001912	potential frameshift: common BLAST hit: gi|385813445|ref|YP_005849838.1| Transposase ISLhe15
880633001913	potential frameshift: common BLAST hit: gi|385813445|ref|YP_005849838.1| Transposase ISLhe15
880633001914	OsmC-like protein; Region: OsmC; cl00767
880633001915	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
880633001916	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_4; cd12162
880633001917	putative ligand binding site [chemical binding]; other site
880633001918	putative NAD binding site [chemical binding]; other site
880633001919	catalytic site [active]
880633001920	potential frameshift: common BLAST hit: gi|116630242|ref|YP_815414.1| N-acetylglucosamine and glucose PTS, EIICBA
880633001921	benzoate transport; Region: 2A0115; TIGR00895
880633001922	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
880633001923	putative substrate translocation pore; other site
880633001924	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
880633001925	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
880633001926	active site
880633001927	metal binding site [ion binding]; metal-binding site
880633001928	Protein of unknown function DUF137; Region: DUF137; cl03400
880633001929	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
880633001930	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
880633001931	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
880633001932	peptide binding site [polypeptide binding]; other site
880633001933	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
880633001934	Metallo-dependent hydrolases, subgroup A is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_A; cd01299
880633001935	Amidohydrolase; Region: Amidohydro_4; pfam13147
880633001936	active site
880633001937	phosphate-starvation-inducible protein PsiE; Provisional; Region: PRK02833
880633001938	galactokinase; Provisional; Region: PRK05322
880633001939	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
880633001940	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK05270
880633001941	Galactose-1-phosphate uridyl transferase, N-terminal domain; Region: GalP_UDP_transf; pfam01087
880633001942	Galactose-1-phosphate uridyl transferase, C-terminal domain; Region: GalP_UDP_tr_C; pfam02744
880633001943	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
880633001944	active site
880633001945	catalytic residues [active]
880633001946	potential frameshift: common BLAST hit: gi|385824975|ref|YP_005861317.1| putative transposase
880633001947	potential frameshift: common BLAST hit: gi|327399881|ref|YP_004340721.1| ABC transporter ATPase
880633001948	YcaO-like family; Region: YcaO; pfam02624
880633001949	This family is the oxydase domain of NRPS (non-ribosomal peptide synthetase) and other proteins that modify polypeptides by cyclizing a thioester to form a ring. These include epoB, part of the epothilone biosynthesis pathway; tubD, part of the tubulysin...; Region: mcbC-like_oxidoreductase; cd02142
880633001950	putative FMN binding site [chemical binding]; other site
880633001951	NADPH bind site [chemical binding]; other site
880633001952	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
880633001953	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
880633001954	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
880633001955	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
880633001956	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
880633001957	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
880633001958	intermolecular recognition site; other site
880633001959	active site
880633001960	dimerization interface [polypeptide binding]; other site
880633001961	Transcriptional regulatory protein, C terminal; Region: Trans_reg_C; smart00862
880633001962	DNA binding site [nucleotide binding]
880633001963	potential frameshift: common BLAST hit: gi|58337701|ref|YP_194286.1| histidine protein kinase
880633001964	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
880633001965	putative substrate translocation pore; other site
880633001966	Major Facilitator Superfamily; Region: MFS_1; pfam07690
880633001967	OsmC-like protein; Region: OsmC; pfam02566
880633001968	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cl00470
880633001969	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
880633001970	active site
880633001971	catalytic tetrad [active]
880633001972	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
880633001973	Double zinc ribbon; Region: DZR; pfam12773
880633001974	type I restriction enzyme EcoKI subunit R; Provisional; Region: hsdR; PRK11448
880633001975	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
880633001976	ATP binding site [chemical binding]; other site
880633001977	putative Mg++ binding site [ion binding]; other site
880633001978	potential frameshift: common BLAST hit: gi|385813474|ref|YP_005849867.1| Site-specific DNA-methyltransferase (Adenine-specific)
880633001979	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
880633001980	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
880633001981	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
880633001982	potential frameshift: common BLAST hit: gi|336054373|ref|YP_004562660.1| transposase
880633001983	Restriction endonuclease [Defense mechanisms]; Region: Mrr; COG1715
880633001984	Mrr N-terminal domain; Region: Mrr_N; pfam14338
880633001985	Restriction endonuclease; Region: Mrr_cat; pfam04471
880633001986	potential frameshift: common BLAST hit: gi|268319546|ref|YP_003293202.1| transposase
880633001987	potential frameshift: common BLAST hit: gi|315037659|ref|YP_004031227.1| transposase
880633001988	DNA methylase; Region: N6_N4_Mtase; pfam01555
880633001989	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
880633001990	legume lectins; Region: lectin_L-type; cd01951
880633001991	homotetramer interaction site [polypeptide binding]; other site
880633001992	carbohydrate binding site [chemical binding]; other site
880633001993	metal binding site [ion binding]; metal-binding site
880633001994	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
880633001995	MucBP domain; Region: MucBP; pfam06458
880633001996	MucBP domain; Region: MucBP; pfam06458
880633001997	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
880633001998	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
880633001999	potential frameshift: common BLAST hit: gi|161507568|ref|YP_001577522.1| transposase
880633002000	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
880633002001	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
880633002002	potential frameshift: common BLAST hit: gi|385817984|ref|YP_005854374.1| surface layer protein
880633002003	The substrate binding component of an ABC-type lactococcal OppA-like transport system contains; Region: PBP2_Lactococcal_OppA_like; cd08510
880633002004	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
880633002005	peptide binding site [polypeptide binding]; other site
880633002006	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
880633002007	dimer interface [polypeptide binding]; other site
880633002008	conserved gate region; other site
880633002009	putative PBP binding loops; other site
880633002010	ABC-ATPase subunit interface; other site
880633002011	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
880633002012	dimer interface [polypeptide binding]; other site
880633002013	conserved gate region; other site
880633002014	putative PBP binding loops; other site
880633002015	ABC-ATPase subunit interface; other site
880633002016	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
880633002017	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
880633002018	Walker A/P-loop; other site
880633002019	ATP binding site [chemical binding]; other site
880633002020	Q-loop/lid; other site
880633002021	ABC transporter signature motif; other site
880633002022	Walker B; other site
880633002023	D-loop; other site
880633002024	H-loop/switch region; other site
880633002025	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
880633002026	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
880633002027	substrate binding pocket [chemical binding]; other site
880633002028	membrane-bound complex binding site; other site
880633002029	hinge residues; other site
880633002030	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
880633002031	Serine dehydratase alpha chain; Region: SDH_alpha; cl12120
880633002032	L-serine deaminase [Amino acid transport and metabolism]; Region: SdaA; COG1760
880633002033	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
880633002034	Bacterial surface layer protein; Region: SLAP; pfam03217
880633002035	SCP: SCP-like extracellular protein domain, found in eukaryotes and prokaryotes. This family includes plant pathogenesis-related protein 1 (PR-1), which accumulates after infections with pathogens, and may act as an anti-fungal agent or be involved in...; Region: SCP; cl00133
880633002036	Major Facilitator Superfamily; Region: MFS_1; pfam07690
880633002037	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
880633002038	putative substrate translocation pore; other site
880633002039	Domain of unknown function (DUF4160); Region: DUF4160; pfam13711
880633002040	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
880633002041	Transposase; Region: DDE_Tnp_ISL3; pfam01610
880633002042	Helix-turn-helix domain of transposase family ISL3; Region: HTH_Tnp_ISL3; pfam13542
880633002043	Transposase; Region: DDE_Tnp_ISL3; pfam01610
880633002044	Zinc-dependent metalloprotease, MMP_like subfamily. This group contains matrix metalloproteinases (MMPs), serralysins, and the astacin_like family of proteases; Region: ZnMc_MMP_like; cd04268
880633002045	active site
880633002046	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
880633002047	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
880633002048	Cl- selectivity filter; other site
880633002049	Cl- binding residues [ion binding]; other site
880633002050	pore gating glutamate residue; other site
880633002051	dimer interface [polypeptide binding]; other site
880633002052	H+/Cl- coupling transport residue; other site
880633002053	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
880633002054	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
880633002055	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
880633002056	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
880633002057	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
880633002058	motif II; other site
880633002059	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
880633002060	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
880633002061	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
880633002062	Cl- selectivity filter; other site
880633002063	Cl- binding residues [ion binding]; other site
880633002064	pore gating glutamate residue; other site
880633002065	dimer interface [polypeptide binding]; other site
880633002066	H+/Cl- coupling transport residue; other site
880633002067	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
880633002068	active site
880633002069	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
880633002070	active site
880633002071	dimer interface [polypeptide binding]; other site
880633002072	Dihydroorotate dehydrogenase (DHOD) class 1B FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine...; Region: DHOD_1B_like; cd04740
880633002073	dihydroorotate dehydrogenase (subfamily 1) family protein; Region: pyrD_sub1_fam; TIGR01037
880633002074	heterodimer interface [polypeptide binding]; other site
880633002075	active site
880633002076	FMN binding site [chemical binding]; other site
880633002077	homodimer interface [polypeptide binding]; other site
880633002078	substrate binding site [chemical binding]; other site
880633002079	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
880633002080	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
880633002081	active site
880633002082	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
880633002083	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
880633002084	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
880633002085	dihydroorotase; Validated; Region: pyrC; PRK09357
880633002086	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
880633002087	Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317
880633002088	active site
880633002089	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
880633002090	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; pfam00988
880633002091	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
880633002092	catalytic site [active]
880633002093	subunit interface [polypeptide binding]; other site
880633002094	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
880633002095	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
880633002096	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
880633002097	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
880633002098	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
880633002099	ATP-grasp domain; Region: ATP-grasp_4; cl17255
880633002100	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
880633002101	IMP binding site; other site
880633002102	dimer interface [polypeptide binding]; other site
880633002103	YSIRK type signal peptide; Region: YSIRK_signal; pfam04650
880633002104	Sugar transport protein; Region: Sugar_transport; pfam06800
880633002105	methionine sulfoxide reductase B; Provisional; Region: PRK00222
880633002106	SelR domain; Region: SelR; pfam01641
880633002107	x-prolyl-dipeptidyl aminopeptidase; Provisional; Region: PRK05371
880633002108	X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal; Region: PepX_N; smart00940
880633002109	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; pfam08530
880633002110	Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX)...; Region: ArsC_like; cd03036
880633002111	ArsC family; Region: ArsC; pfam03960
880633002112	putative ArsC-like catalytic residues; other site
880633002113	putative TRX-like catalytic residues [active]
880633002114	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
880633002115	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
880633002116	substrate binding pocket [chemical binding]; other site
880633002117	Cpl-1 lysin (also known as Cpl-9 lysozyme / muramidase) is a bacterial cell wall endolysin encoded by the pneumococcal bacteriophage Cp-1, which cleaves the glycosidic N-acetylmuramoyl-(beta1,4)-N-acetylglucosamine bonds of the pneumococcal glycan chain; Region: GH25_Cpl1-like; cd06415
880633002118	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
880633002119	active site
880633002120	Bacterial surface layer protein; Region: SLAP; pfam03217
880633002121	Predicted membrane protein (DUF2207); Region: DUF2207; pfam09972
880633002122	4-oxalocrotonate tautomerase; Provisional; Region: PRK02220
880633002123	active site 1 [active]
880633002124	dimer interface [polypeptide binding]; other site
880633002125	hexamer interface [polypeptide binding]; other site
880633002126	active site 2 [active]
880633002127	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49); Region: G6PD_bact; pfam10786
880633002128	Helix-turn-helix domain of transposase family ISL3; Region: HTH_Tnp_ISL3; pfam13542
880633002129	Transposase; Region: DDE_Tnp_ISL3; pfam01610
880633002130	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
880633002131	Transposase; Region: DDE_Tnp_ISL3; pfam01610
880633002132	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
880633002133	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
880633002134	homodimer interface [polypeptide binding]; other site
880633002135	substrate-cofactor binding pocket; other site
880633002136	catalytic residue [active]
880633002137	Uncharacterized protein conserved in bacteria (DUF2325); Region: DUF2325; pfam10087
880633002138	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
880633002139	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
880633002140	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
880633002141	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
880633002142	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
880633002143	active site
880633002144	elongation factor P; Validated; Region: PRK00529
880633002145	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
880633002146	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
880633002147	RNA binding site [nucleotide binding]; other site
880633002148	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
880633002149	RNA binding site [nucleotide binding]; other site
880633002150	Asp23 family; Region: Asp23; pfam03780
880633002151	transcription antitermination factor NusB; Region: nusB; TIGR01951
880633002152	putative RNA binding site [nucleotide binding]; other site
880633002153	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14190
880633002154	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
880633002155	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
880633002156	homodimer interface [polypeptide binding]; other site
880633002157	NADP binding site [chemical binding]; other site
880633002158	substrate binding site [chemical binding]; other site
880633002159	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
880633002160	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
880633002161	generic binding surface II; other site
880633002162	generic binding surface I; other site
880633002163	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
880633002164	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
880633002165	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
880633002166	substrate binding pocket [chemical binding]; other site
880633002167	chain length determination region; other site
880633002168	substrate-Mg2+ binding site; other site
880633002169	catalytic residues [active]
880633002170	aspartate-rich region 1; other site
880633002171	active site lid residues [active]
880633002172	aspartate-rich region 2; other site
880633002173	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
880633002174	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
880633002175	RNA binding surface [nucleotide binding]; other site
880633002176	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
880633002177	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
880633002178	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
880633002179	Walker A/P-loop; other site
880633002180	ATP binding site [chemical binding]; other site
880633002181	Q-loop/lid; other site
880633002182	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
880633002183	ABC transporter signature motif; other site
880633002184	Walker B; other site
880633002185	D-loop; other site
880633002186	H-loop/switch region; other site
880633002187	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
880633002188	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
880633002189	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
880633002190	catalytic site [active]
880633002191	DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392
880633002192	Primosomal protein N' (replication factor Y) - superfamily II helicase [DNA replication, recombination, and repair]; Region: PriA; COG1198
880633002193	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
880633002194	ATP binding site [chemical binding]; other site
880633002195	putative Mg++ binding site [ion binding]; other site
880633002196	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
880633002197	nucleotide binding region [chemical binding]; other site
880633002198	ATP-binding site [chemical binding]; other site
880633002199	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
880633002200	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
880633002201	putative active site [active]
880633002202	substrate binding site [chemical binding]; other site
880633002203	putative cosubstrate binding site; other site
880633002204	catalytic site [active]
880633002205	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
880633002206	substrate binding site [chemical binding]; other site
880633002207	16S rRNA methyltransferase B; Provisional; Region: PRK14902
880633002208	NusB family; Region: NusB; pfam01029
880633002209	putative RNA binding site [nucleotide binding]; other site
880633002210	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
880633002211	S-adenosylmethionine binding site [chemical binding]; other site
880633002212	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
880633002213	Protein phosphatase 2C; Region: PP2C; pfam00481
880633002214	active site
880633002215	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
880633002216	Catalytic domain of Protein Kinases; Region: PKc; cd00180
880633002217	active site
880633002218	ATP binding site [chemical binding]; other site
880633002219	substrate binding site [chemical binding]; other site
880633002220	activation loop (A-loop); other site
880633002221	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
880633002222	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2815
880633002223	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
880633002224	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
880633002225	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
880633002226	GTPase RsgA; Reviewed; Region: PRK00098
880633002227	S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466
880633002228	RNA binding site [nucleotide binding]; other site
880633002229	homodimer interface [polypeptide binding]; other site
880633002230	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
880633002231	GTPase/Zn-binding domain interface [polypeptide binding]; other site
880633002232	GTP/Mg2+ binding site [chemical binding]; other site
880633002233	G4 box; other site
880633002234	G5 box; other site
880633002235	G1 box; other site
880633002236	Switch I region; other site
880633002237	G2 box; other site
880633002238	G3 box; other site
880633002239	Switch II region; other site
880633002240	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
880633002241	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
880633002242	substrate binding site [chemical binding]; other site
880633002243	hexamer interface [polypeptide binding]; other site
880633002244	metal binding site [ion binding]; metal-binding site
880633002245	Thiamine pyrophosphokinase; Region: TPK; cd07995
880633002246	thiamine pyrophosphokinase; Region: thi_PPkinase; TIGR01378
880633002247	active site
880633002248	dimerization interface [polypeptide binding]; other site
880633002249	thiamine binding site [chemical binding]; other site
880633002250	SOCS (suppressors of cytokine signaling) box. The SOCS box is found in the C-terminal region of CIS/SOCS family proteins (in combination with a SH2 domain), ASBs (ankyrin repeat-containing proteins with a SOCS box), SSBs (SPRY domain-containing proteins...; Region: SOCS; cl02533
880633002251	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
880633002252	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1302
880633002253	DAK2 domain fusion protein YloV; Region: YloV; TIGR03599
880633002254	DAK2 domain; Region: Dak2; pfam02734
880633002255	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
880633002256	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
880633002257	ssDNA binding site; other site
880633002258	generic binding surface II; other site
880633002259	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
880633002260	ATP binding site [chemical binding]; other site
880633002261	putative Mg++ binding site [ion binding]; other site
880633002262	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
880633002263	nucleotide binding region [chemical binding]; other site
880633002264	ATP-binding site [chemical binding]; other site
880633002265	putative phosphate acyltransferase; Provisional; Region: PRK05331
880633002266	acyl carrier protein; Provisional; Region: acpP; PRK00982
880633002267	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
880633002268	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
880633002269	Walker A/P-loop; other site
880633002270	ATP binding site [chemical binding]; other site
880633002271	Q-loop/lid; other site
880633002272	ABC transporter signature motif; other site
880633002273	Walker B; other site
880633002274	D-loop; other site
880633002275	H-loop/switch region; other site
880633002276	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
880633002277	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
880633002278	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
880633002279	Walker A/P-loop; other site
880633002280	ATP binding site [chemical binding]; other site
880633002281	Q-loop/lid; other site
880633002282	ABC transporter signature motif; other site
880633002283	Walker B; other site
880633002284	D-loop; other site
880633002285	H-loop/switch region; other site
880633002286	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
880633002287	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
880633002288	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
880633002289	dimer interface [polypeptide binding]; other site
880633002290	conserved gate region; other site
880633002291	putative PBP binding loops; other site
880633002292	ABC-ATPase subunit interface; other site
880633002293	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
880633002294	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
880633002295	dimer interface [polypeptide binding]; other site
880633002296	conserved gate region; other site
880633002297	putative PBP binding loops; other site
880633002298	ABC-ATPase subunit interface; other site
880633002299	The substrate binding component of an ABC-type lactococcal OppA-like transport system contains; Region: PBP2_Lactococcal_OppA_like; cd08510
880633002300	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
880633002301	peptide binding site [polypeptide binding]; other site
880633002302	The substrate binding component of an ABC-type lactococcal OppA-like transport system contains; Region: PBP2_Lactococcal_OppA_like; cd08510
880633002303	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
880633002304	peptide binding site [polypeptide binding]; other site
880633002305	ribonuclease III; Reviewed; Region: rnc; PRK00102
880633002306	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
880633002307	dimerization interface [polypeptide binding]; other site
880633002308	active site
880633002309	metal binding site [ion binding]; metal-binding site
880633002310	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
880633002311	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
880633002312	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
880633002313	Walker A/P-loop; other site
880633002314	ATP binding site [chemical binding]; other site
880633002315	Q-loop/lid; other site
880633002316	SMC proteins Flexible Hinge Domain; Region: SMC_hinge; smart00968
880633002317	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
880633002318	ABC transporter signature motif; other site
880633002319	Walker B; other site
880633002320	D-loop; other site
880633002321	H-loop/switch region; other site
880633002322	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
880633002323	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
880633002324	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
880633002325	P loop; other site
880633002326	GTP binding site [chemical binding]; other site
880633002327	Peptidase family C69; Region: Peptidase_C69; pfam03577
880633002328	Transcriptional regulators [Transcription]; Region: MarR; COG1846
880633002329	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
880633002330	Transposase; Region: DDE_Tnp_ISL3; pfam01610
880633002331	Transposase; Region: DEDD_Tnp_IS110; pfam01548
880633002332	Transposase; Region: DEDD_Tnp_IS110; pfam01548
880633002333	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
880633002334	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
880633002335	Transposase, Mutator family; Region: Transposase_mut; pfam00872
880633002336	MULE transposase domain; Region: MULE; pfam10551
880633002337	potential frameshift: common BLAST hit: gi|336053840|ref|YP_004562127.1| transposase
880633002338	amino acid transporter; Region: 2A0306; TIGR00909
880633002339	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
880633002340	putative DNA-binding protein; Validated; Region: PRK00118
880633002341	Putative helix-turn-helix protein, YlxM / p13 like; Region: UPF0122; pfam04297
880633002342	signal recognition particle protein; Provisional; Region: PRK10867
880633002343	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
880633002344	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
880633002345	P loop; other site
880633002346	GTP binding site [chemical binding]; other site
880633002347	Signal peptide binding domain; Region: SRP_SPB; pfam02978
880633002348	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
880633002349	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
880633002350	RimM N-terminal domain; Region: RimM; pfam01782
880633002351	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
880633002352	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
880633002353	Family 4 Uracil-DNA glycosylase (UDG), found exclusively in thermophilic organisms; Region: UDG_F4_TTUDGA_like; cd10030
880633002354	active site
880633002355	Fe-S cluster binding site [ion binding]; other site
880633002356	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
880633002357	active site
880633002358	catalytic triad [active]
880633002359	oxyanion hole [active]
880633002360	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
880633002361	putative DNA binding site [nucleotide binding]; other site
880633002362	LexA repressor; Validated; Region: PRK00215
880633002363	putative Zn2+ binding site [ion binding]; other site
880633002364	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
880633002365	Catalytic site [active]
880633002366	Bacterial protein of unknown function (DUF896); Region: DUF896; pfam05979
880633002367	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3763
880633002368	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
880633002369	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
880633002370	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
880633002371	Walker A/P-loop; other site
880633002372	ATP binding site [chemical binding]; other site
880633002373	Q-loop/lid; other site
880633002374	ABC transporter signature motif; other site
880633002375	Walker B; other site
880633002376	D-loop; other site
880633002377	H-loop/switch region; other site
880633002378	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
880633002379	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
880633002380	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
880633002381	Walker A/P-loop; other site
880633002382	ATP binding site [chemical binding]; other site
880633002383	Q-loop/lid; other site
880633002384	ABC transporter signature motif; other site
880633002385	Walker B; other site
880633002386	D-loop; other site
880633002387	H-loop/switch region; other site
880633002388	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
880633002389	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
880633002390	active site
880633002391	Zn binding site [ion binding]; other site
880633002392	Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane]; Region: Cfa; COG2230
880633002393	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
880633002394	S-adenosylmethionine binding site [chemical binding]; other site
880633002395	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
880633002396	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
880633002397	putative acyl-acceptor binding pocket; other site
880633002398	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
880633002399	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
880633002400	S-adenosylmethionine binding site [chemical binding]; other site
880633002401	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
880633002402	GIY-YIG motif/motif A; other site
880633002403	putative active site [active]
880633002404	putative metal binding site [ion binding]; other site
880633002405	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
880633002406	rRNA interaction site [nucleotide binding]; other site
880633002407	S8 interaction site; other site
880633002408	putative laminin-1 binding site; other site
880633002409	elongation factor Ts; Provisional; Region: tsf; PRK09377
880633002410	UBA/TS-N domain; Region: UBA; pfam00627
880633002411	Elongation factor TS; Region: EF_TS; pfam00889
880633002412	Elongation factor TS; Region: EF_TS; pfam00889
880633002413	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
880633002414	putative nucleotide binding site [chemical binding]; other site
880633002415	uridine monophosphate binding site [chemical binding]; other site
880633002416	homohexameric interface [polypeptide binding]; other site
880633002417	ribosome recycling factor; Reviewed; Region: frr; PRK00083
880633002418	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
880633002419	hinge region; other site
880633002420	undecaprenyl pyrophosphate synthase; Provisional; Region: PRK14830
880633002421	Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255
880633002422	catalytic residue [active]
880633002423	putative FPP diphosphate  binding site; other site
880633002424	putative FPP binding hydrophobic cleft; other site
880633002425	dimer interface [polypeptide binding]; other site
880633002426	putative IPP diphosphate binding site; other site
880633002427	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
880633002428	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
880633002429	RIP metalloprotease RseP; Region: TIGR00054
880633002430	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
880633002431	active site
880633002432	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
880633002433	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
880633002434	protein binding site [polypeptide binding]; other site
880633002435	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
880633002436	putative substrate binding region [chemical binding]; other site
880633002437	prolyl-tRNA synthetase; Provisional; Region: PRK09194
880633002438	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
880633002439	dimer interface [polypeptide binding]; other site
880633002440	motif 1; other site
880633002441	active site
880633002442	motif 2; other site
880633002443	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
880633002444	putative deacylase active site [active]
880633002445	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
880633002446	active site
880633002447	motif 3; other site
880633002448	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
880633002449	anticodon binding site; other site
880633002450	DNA polymerase III PolC; Validated; Region: polC; PRK00448
880633002451	DNA polymerase III polC-type N-terminus; Region: DNA_pol3_alph_N; pfam11490
880633002452	polC_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold nucleic acid binding domain of Bacillus subtilis type C replicative DNA polymerase III alpha subunit (polC). Replication in B. subtilis and Staphylococcus aureus requires two...; Region: polC_OBF; cd04484
880633002453	generic binding surface II; other site
880633002454	generic binding surface I; other site
880633002455	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
880633002456	active site
880633002457	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
880633002458	active site
880633002459	catalytic site [active]
880633002460	substrate binding site [chemical binding]; other site
880633002461	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III at PolC gene; Region: PHP_PolIIIA_POLC; cd07435
880633002462	potential frameshift: common BLAST hit: gi|161507702|ref|YP_001577658.1| transposase
880633002463	potential frameshift: common BLAST hit: gi|385813445|ref|YP_005849838.1| Transposase ISLhe15
880633002464	ribosome maturation protein RimP; Reviewed; Region: PRK00092
880633002465	Sm and related proteins; Region: Sm_like; cl00259
880633002466	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
880633002467	putative oligomer interface [polypeptide binding]; other site
880633002468	putative RNA binding site [nucleotide binding]; other site
880633002469	transcription elongation factor NusA; Provisional; Region: nusA; PRK12327
880633002470	NusA N-terminal domain; Region: NusA_N; pfam08529
880633002471	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
880633002472	RNA binding site [nucleotide binding]; other site
880633002473	homodimer interface [polypeptide binding]; other site
880633002474	NusA-like KH domain; Region: KH_5; pfam13184
880633002475	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
880633002476	G-X-X-G motif; other site
880633002477	Ylxr homologs; group of conserved hypothetical bacterial proteins of unknown function; structure revealed putative RNA binding cleft; proteins are encoded by an operon that includes other proteins involved in transcription and/or translation; Region: YlxR; cd00279
880633002478	putative RNA binding cleft [nucleotide binding]; other site
880633002479	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; Region: Ribosomal_L7Ae; cl00600
880633002480	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
880633002481	translation initiation factor IF-2; Region: IF-2; TIGR00487
880633002482	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
880633002483	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
880633002484	G1 box; other site
880633002485	putative GEF interaction site [polypeptide binding]; other site
880633002486	GTP/Mg2+ binding site [chemical binding]; other site
880633002487	Switch I region; other site
880633002488	G2 box; other site
880633002489	G3 box; other site
880633002490	Switch II region; other site
880633002491	G4 box; other site
880633002492	G5 box; other site
880633002493	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
880633002494	Translation-initiation factor 2; Region: IF-2; pfam11987
880633002495	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
880633002496	Ribosome-binding factor A; Region: RBFA; cl00542
880633002497	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK02484
880633002498	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
880633002499	RNA binding site [nucleotide binding]; other site
880633002500	active site
880633002501	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
880633002502	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
880633002503	active site
880633002504	Riboflavin kinase; Region: Flavokinase; pfam01687
880633002505	heat-inducible transcription repressor; Provisional; Region: hrcA; PRK00082
880633002506	Winged helix-turn-helix transcription repressor, HrcA DNA-binding; Region: HrcA_DNA-bdg; pfam03444
880633002507	GrpE; Region: GrpE; pfam01025
880633002508	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
880633002509	dimer interface [polypeptide binding]; other site
880633002510	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
880633002511	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
880633002512	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
880633002513	nucleotide binding site [chemical binding]; other site
880633002514	NEF interaction site [polypeptide binding]; other site
880633002515	SBD interface [polypeptide binding]; other site
880633002516	chaperone protein DnaJ; Provisional; Region: PRK14276
880633002517	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
880633002518	HSP70 interaction site [polypeptide binding]; other site
880633002519	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
880633002520	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
880633002521	dimer interface [polypeptide binding]; other site
880633002522	GTP-binding protein LepA; Provisional; Region: PRK05433
880633002523	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
880633002524	G1 box; other site
880633002525	putative GEF interaction site [polypeptide binding]; other site
880633002526	GTP/Mg2+ binding site [chemical binding]; other site
880633002527	Switch I region; other site
880633002528	G2 box; other site
880633002529	G3 box; other site
880633002530	Switch II region; other site
880633002531	G4 box; other site
880633002532	G5 box; other site
880633002533	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
880633002534	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
880633002535	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
880633002536	Sortase A (SrtA) or subfamily-1 sortases are cysteine transpeptidases found in gram-positive bacteria that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. They do so by catalyzing a transpeptidation reaction in which the...; Region: Sortase_A_1; cd06165
880633002537	active site
880633002538	catalytic site [active]
880633002539	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
880633002540	DHH family; Region: DHH; pfam01368
880633002541	DHHA1 domain; Region: DHHA1; pfam02272
880633002542	Single-strand DNA-specific exonuclease, C terminal domain; Region: ssDNA-exonuc_C; cl11538
880633002543	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
880633002544	active site
880633002545	potential frameshift: common BLAST hit: gi|161507670|ref|YP_001577624.1| cysteine synthase
880633002546	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
880633002547	conserved cys residue [active]
880633002548	potential frameshift: common BLAST hit: gi|161507668|ref|YP_001577622.1| cardiolipin synthase
880633002549	potential frameshift: common BLAST hit: gi|385813638|ref|YP_005850031.1| Cardiolipin synthetase
880633002550	Bacterial surface layer protein; Region: SLAP; pfam03217
880633002551	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
880633002552	plasma-membrane proton-efflux P-type ATPase; Region: ATPase-IIIA_H; TIGR01647
880633002553	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
880633002554	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
880633002555	motif II; other site
880633002556	Transcriptional regulator [Transcription]; Region: LysR; COG0583
880633002557	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
880633002558	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
880633002559	dimerization interface [polypeptide binding]; other site
880633002560	arginine deiminase; Provisional; Region: PRK01388
880633002561	ornithine carbamoyltransferase; Validated; Region: PRK02102
880633002562	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
880633002563	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
880633002564	carbamate kinase; Reviewed; Region: PRK12686
880633002565	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
880633002566	putative substrate binding site [chemical binding]; other site
880633002567	nucleotide binding site [chemical binding]; other site
880633002568	nucleotide binding site [chemical binding]; other site
880633002569	homodimer interface [polypeptide binding]; other site
880633002570	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase; Region: CitX; pfam03802
880633002571	Acetyltransferase (GNAT) domain; Region: Acetyltransf_9; pfam13527
880633002572	Sterol carrier protein domain; Region: SCP2_2; pfam13530
880633002573	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
880633002574	Transcriptional regulator [Transcription]; Region: LysR; COG0583
880633002575	dimerization interface [polypeptide binding]; other site
880633002576	potential frameshift: common BLAST hit: gi|385813651|ref|YP_005850044.1| Aspartokinase
880633002577	potential frameshift: common BLAST hit: gi|336053981|ref|YP_004562268.1| aspartokinase
880633002578	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
880633002579	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
880633002580	pyridoxal 5'-phosphate binding site [chemical binding]; other site
880633002581	catalytic residue [active]
880633002582	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
880633002583	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
880633002584	homoserine kinase; Provisional; Region: PRK01212
880633002585	potential frameshift: common BLAST hit: gi|385817789|ref|YP_005854179.1| homoserine kinase
880633002586	MuDR family transposase; Region: DBD_Tnp_Mut; pfam03108
880633002587	Uncharacterized conserved protein [Function unknown]; Region: COG1284
880633002588	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
880633002589	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
880633002590	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
880633002591	Peptidase family M23; Region: Peptidase_M23; pfam01551
880633002592	Kinase/pyrophosphorylase; Region: Kinase-PPPase; pfam03618
880633002593	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
880633002594	Yqey-like protein; Region: YqeY; pfam09424
880633002595	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
880633002596	PhoH-like protein; Region: PhoH; pfam02562
880633002597	metal-binding heat shock protein; Provisional; Region: PRK00016
880633002598	GTPase Era; Reviewed; Region: era; PRK00089
880633002599	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
880633002600	G1 box; other site
880633002601	GTP/Mg2+ binding site [chemical binding]; other site
880633002602	Switch I region; other site
880633002603	G2 box; other site
880633002604	Switch II region; other site
880633002605	G3 box; other site
880633002606	G4 box; other site
880633002607	G5 box; other site
880633002608	Recombination protein O N terminal; Region: RecO_N; pfam11967
880633002609	DNA repair protein RecO; Region: reco; TIGR00613
880633002610	Recombination protein O C terminal; Region: RecO_C; pfam02565
880633002611	glycyl-tRNA synthetase subunit alpha; Validated; Region: glyQ; PRK09348
880633002612	motif 1; other site
880633002613	dimer interface [polypeptide binding]; other site
880633002614	active site
880633002615	motif 2; other site
880633002616	motif 3; other site
880633002617	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
880633002618	DALR anticodon binding domain; Region: DALR_1; pfam05746
880633002619	DNA primase; Validated; Region: dnaG; PRK05667
880633002620	CHC2 zinc finger; Region: zf-CHC2; cl17510
880633002621	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
880633002622	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
880633002623	active site
880633002624	metal binding site [ion binding]; metal-binding site
880633002625	interdomain interaction site; other site
880633002626	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
880633002627	RNA polymerase sigma factor RpoD; Validated; Region: PRK09210
880633002628	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
880633002629	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
880633002630	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
880633002631	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
880633002632	DNA binding residues [nucleotide binding]
880633002633	Peptidase family M23; Region: Peptidase_M23; pfam01551
880633002634	MutT homolog-1 (MTH1) is a member of the Nudix hydrolase superfamily. MTH1, the mammalian counterpart of MutT, hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP and 2-hydroxy-ATP, to monophosphates, thereby preventing the...; Region: MTH1; cd03427
880633002635	putative active site [active]
880633002636	nucleotide binding site [chemical binding]; other site
880633002637	nudix motif; other site
880633002638	putative metal binding site [ion binding]; other site
880633002639	Predicted SAM-dependent methyltransferase [General function prediction only]; Region: COG2384
880633002640	Family of unknown function (DUF633); Region: DUF633; pfam04816
880633002641	Uncharacterized conserved protein [Function unknown]; Region: COG0327
880633002642	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
880633002643	peptidase T; Region: peptidase-T; TIGR01882
880633002644	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
880633002645	metal binding site [ion binding]; metal-binding site
880633002646	dimer interface [polypeptide binding]; other site
880633002647	Predicted transcriptional regulators [Transcription]; Region: COG1725
880633002648	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
880633002649	DNA-binding site [nucleotide binding]; DNA binding site
880633002650	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
880633002651	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
880633002652	Walker A/P-loop; other site
880633002653	ATP binding site [chemical binding]; other site
880633002654	Q-loop/lid; other site
880633002655	ABC transporter signature motif; other site
880633002656	Walker B; other site
880633002657	D-loop; other site
880633002658	H-loop/switch region; other site
880633002659	recombination factor protein RarA; Reviewed; Region: PRK13342
880633002660	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
880633002661	Walker A motif; other site
880633002662	ATP binding site [chemical binding]; other site
880633002663	Walker B motif; other site
880633002664	arginine finger; other site
880633002665	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
880633002666	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
880633002667	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
880633002668	Catalytic site [active]
880633002669	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
880633002670	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
880633002671	S-adenosylmethionine binding site [chemical binding]; other site
880633002672	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
880633002673	isopentenyl pyrophosphate isomerase; Provisional; Region: PRK05437
880633002674	Isopentenyl-diphosphate:dimethylallyl diphosphate isomerase type 2 (IDI-2) FMN-binding domain. Two types of IDIs have been characterized at present. The long known IDI-1 is only dependent on divalent metals for activity, whereas IDI-2 requires a metal; Region: IDI-2_FMN; cd02811
880633002675	homotetramer interface [polypeptide binding]; other site
880633002676	FMN binding site [chemical binding]; other site
880633002677	homodimer contacts [polypeptide binding]; other site
880633002678	putative active site [active]
880633002679	putative substrate binding site [chemical binding]; other site
880633002680	phosphomevalonate kinase, ERG8-type, Gram-positive branch; Region: Pmev_kin_Gr_pos; TIGR01220
880633002681	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
880633002682	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
880633002683	diphosphomevalonate decarboxylase; Region: PLN02407
880633002684	Mevalonate pyrophosphate decarboxylase [Lipid metabolism]; Region: MVD1; COG3407
880633002685	mevalonate kinase; Region: mevalon_kin; TIGR00549
880633002686	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
880633002687	helicase-exonuclease AddAB, AddB subunit; Region: addB_Gpos; TIGR02773
880633002688	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
880633002689	helicase-exonuclease AddAB, AddA subunit, Firmicutes type; Region: addA_Gpos; TIGR02785
880633002690	Part of AAA domain; Region: AAA_19; pfam13245
880633002691	Family description; Region: UvrD_C_2; pfam13538
880633002692	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cl00641
880633002693	bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated; Region: PRK08074
880633002694	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
880633002695	active site
880633002696	catalytic site [active]
880633002697	substrate binding site [chemical binding]; other site
880633002698	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
880633002699	ATP binding site [chemical binding]; other site
880633002700	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
880633002701	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5353
880633002702	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
880633002703	AsnRS_cyto_like_N: N-terminal, anticodon recognition domain of the type found in human and Saccharomyces cerevisiae cytoplasmic asparaginyl-tRNA synthetase (AsnRS), in Brugia malayai AsnRs and, in various putative bacterial AsnRSs.  This domain is a...; Region: AsnRS_cyto_like_N; cd04323
880633002704	putative dimer interface [polypeptide binding]; other site
880633002705	putative anticodon binding site; other site
880633002706	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
880633002707	homodimer interface [polypeptide binding]; other site
880633002708	motif 1; other site
880633002709	motif 2; other site
880633002710	active site
880633002711	motif 3; other site
880633002712	Helix-turn-helix domain; Region: HTH_36; pfam13730
880633002713	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
880633002714	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
880633002715	endonuclease III; Region: ENDO3c; smart00478
880633002716	minor groove reading motif; other site
880633002717	helix-hairpin-helix signature motif; other site
880633002718	substrate binding pocket [chemical binding]; other site
880633002719	active site
880633002720	Transglycosylase; Region: Transgly; pfam00912
880633002721	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
880633002722	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
880633002723	Holliday junction-specific endonuclease; Reviewed; Region: recU; PRK02234
880633002724	hypothetical protein; Provisional; Region: PRK13660
880633002725	DivIVA protein; Region: DivIVA; pfam05103
880633002726	DivIVA domain; Region: DivI1A_domain; TIGR03544
880633002727	Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0116
880633002728	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
880633002729	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
880633002730	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
880633002731	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
880633002732	active site
880633002733	metal binding site [ion binding]; metal-binding site
880633002734	Uncharacterized protein family (UPF0236); Region: UPF0236; pfam06782
880633002735	formate--tetrahydrofolate ligase; Provisional; Region: PRK13505
880633002736	Formyltetrahydrofolate synthetase (FTHFS) catalyzes the ATP-dependent activation of formate ion via its addition to the N10 position of tetrahydrofolate. FTHFS is a highly expressed key enzyme in both the Wood-Ljungdahl pathway of autotrophic CO2...; Region: FTHFS; cd00477
880633002737	Potassium binding sites [ion binding]; other site
880633002738	Cesium cation binding sites [ion binding]; other site
880633002739	lipoprotein signal peptidase; Provisional; Region: PRK14797
880633002740	lipoprotein signal peptidase; Provisional; Region: PRK14787
880633002741	pseudouridine synthase, RluA family; Region: rluA_subfam; TIGR00005
880633002742	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
880633002743	RNA binding surface [nucleotide binding]; other site
880633002744	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
880633002745	active site
880633002746	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12838
880633002747	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
880633002748	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
880633002749	catalytic site [active]
880633002750	subunit interface [polypeptide binding]; other site
880633002751	potential frameshift: common BLAST hit: gi|385813707|ref|YP_005850100.1| Carbamoyl-phosphate synthase large subunit
880633002752	Fibronectin-binding protein A N-terminus (FbpA); Region: FbpA; pfam05833
880633002753	Domain of unknown function (DUF814); Region: DUF814; pfam05670
880633002754	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
880633002755	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
880633002756	Transcriptional regulators [Transcription]; Region: MarR; COG1846
880633002757	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
880633002758	EDD domain protein, DegV family; Region: DegV; TIGR00762
880633002759	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
880633002760	site-specific tyrosine recombinase XerS; Reviewed; Region: xerS; PRK05084
880633002761	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
880633002762	active site
880633002763	DNA binding site [nucleotide binding]
880633002764	Int/Topo IB signature motif; other site
880633002765	potential frameshift: common BLAST hit: gi|385814641|ref|YP_005851034.1| Transposase IS1201
880633002766	Transposase, Mutator family; Region: Transposase_mut; pfam00872
880633002767	potential frameshift: common BLAST hit: gi|161508084|ref|YP_001578051.1| transposase IS1201
880633002768	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
880633002769	potential frameshift: common BLAST hit: gi|385813712|ref|YP_005850105.1| Putative adenylate kinase DNA topology modulator
880633002770	potential frameshift: common BLAST hit: gi|325956875|ref|YP_004292287.1| lysin
880633002771	Transposase, Mutator family; Region: Transposase_mut; pfam00872
880633002772	Transposase, Mutator family; Region: Transposase_mut; pfam00872
880633002773	MULE transposase domain; Region: MULE; pfam10551
880633002774	potential frameshift: common BLAST hit: gi|385817699|ref|YP_005854089.1| membrane protein
880633002775	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
880633002776	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
880633002777	non-specific DNA binding site [nucleotide binding]; other site
880633002778	salt bridge; other site
880633002779	sequence-specific DNA binding site [nucleotide binding]; other site
880633002780	GDA1/CD39 (nucleoside phosphatase) family; Region: GDA1_CD39; cl17763
880633002781	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family [Posttranslational modification, protein turnover, chaperones]; Region: PpiB; COG0652
880633002782	active site
880633002783	putative manganese-dependent inorganic pyrophosphatase; Provisional; Region: PRK05427
880633002784	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
880633002785	DHHA2 domain; Region: DHHA2; pfam02833
880633002786	Transcriptional regulator [Transcription]; Region: LysR; COG0583
880633002787	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
880633002788	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
880633002789	dimerization interface [polypeptide binding]; other site
880633002790	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
880633002791	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
880633002792	CAP-like domain; other site
880633002793	active site
880633002794	primary dimer interface [polypeptide binding]; other site
880633002795	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
880633002796	DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559
880633002797	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
880633002798	Mg2+ binding site [ion binding]; other site
880633002799	G-X-G motif; other site
880633002800	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
880633002801	anchoring element; other site
880633002802	dimer interface [polypeptide binding]; other site
880633002803	ATP binding site [chemical binding]; other site
880633002804	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
880633002805	active site
880633002806	putative metal-binding site [ion binding]; other site
880633002807	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
880633002808	Glycerol-3-phosphate acyltransferase; Region: G3P_acyltransf; cl00410
880633002809	potential frameshift: common BLAST hit: gi|295693012|ref|YP_003601622.1| non-specific serine/threonine protein kinase
880633002810	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
880633002811	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
880633002812	dimerization interface [polypeptide binding]; other site
880633002813	DPS ferroxidase diiron center [ion binding]; other site
880633002814	ion pore; other site
880633002815	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
880633002816	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
880633002817	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
880633002818	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
880633002819	Helix-turn-helix domain of transposase family ISL3; Region: HTH_Tnp_ISL3; pfam13542
880633002820	Transposase; Region: DDE_Tnp_ISL3; pfam01610
880633002821	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
880633002822	Transposase; Region: DDE_Tnp_ISL3; pfam01610
880633002823	Transposase; Region: DEDD_Tnp_IS110; pfam01548
880633002824	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
880633002825	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
880633002826	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
880633002827	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
880633002828	dimer interface [polypeptide binding]; other site
880633002829	FMN binding site [chemical binding]; other site
880633002830	NADPH bind site [chemical binding]; other site
880633002831	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
880633002832	Alpha/beta hydrolase of unknown function (DUF915); Region: DUF915; pfam06028
880633002833	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes [Energy production and conversion]; Region: Lpd; COG1249
880633002834	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
880633002835	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
880633002836	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
880633002837	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
880633002838	active site
880633002839	DNA binding site [nucleotide binding]
880633002840	Int/Topo IB signature motif; other site
880633002841	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
880633002842	Integrase core domain; Region: rve; pfam00665
880633002843	Uncharacterized protein family (UPF0236); Region: UPF0236; pfam06782
880633002844	HTH-like domain; Region: HTH_21; pfam13276
880633002845	potential frameshift: common BLAST hit: gi|385813799|ref|YP_005850192.1| transposase
880633002846	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
880633002847	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
880633002848	substrate binding pocket [chemical binding]; other site
880633002849	membrane-bound complex binding site; other site
880633002850	hinge residues; other site
880633002851	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
880633002852	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
880633002853	Walker A/P-loop; other site
880633002854	ATP binding site [chemical binding]; other site
880633002855	Q-loop/lid; other site
880633002856	ABC transporter signature motif; other site
880633002857	Walker B; other site
880633002858	D-loop; other site
880633002859	H-loop/switch region; other site
880633002860	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
880633002861	dimer interface [polypeptide binding]; other site
880633002862	conserved gate region; other site
880633002863	putative PBP binding loops; other site
880633002864	ABC-ATPase subunit interface; other site
880633002865	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
880633002866	dimer interface [polypeptide binding]; other site
880633002867	conserved gate region; other site
880633002868	putative PBP binding loops; other site
880633002869	ABC-ATPase subunit interface; other site
880633002870	potential frameshift: common BLAST hit: gi|385813748|ref|YP_005850141.1| MerR family transcriptional regulator
880633002871	Antibiotic biosynthesis monooxygenase; Region: ABM; cl10022
880633002872	maltose O-acetyltransferase; Provisional; Region: PRK10092
880633002873	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
880633002874	putative trimer interface [polypeptide binding]; other site
880633002875	putative CoA binding site [chemical binding]; other site
880633002876	potential frameshift: common BLAST hit: gi|385813752|ref|YP_005850145.1| aminocarboxymuconate-semialdehyde decarboxylase
880633002877	potential frameshift: common BLAST hit: gi|385813752|ref|YP_005850145.1| aminocarboxymuconate-semialdehyde decarboxylase
880633002878	Abi-like protein; Region: Abi_2; pfam07751
880633002879	potential frameshift: common BLAST hit: gi|385813755|ref|YP_005850148.1| RNA 2'-phosphotransferase
880633002880	putative enoyl-[acyl-carrier-protein] reductase II; Region: enACPred_II; TIGR03151
880633002881	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
880633002882	FMN binding site [chemical binding]; other site
880633002883	substrate binding site [chemical binding]; other site
880633002884	putative catalytic residue [active]
880633002885	recombination factor protein RarA; Reviewed; Region: PRK13342
880633002886	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
880633002887	Walker A motif; other site
880633002888	ATP binding site [chemical binding]; other site
880633002889	Walker B motif; other site
880633002890	arginine finger; other site
880633002891	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
880633002892	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
880633002893	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
880633002894	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
880633002895	sequence-specific DNA binding site [nucleotide binding]; other site
880633002896	salt bridge; other site
880633002897	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
880633002898	endonuclease III; Region: ENDO3c; smart00478
880633002899	minor groove reading motif; other site
880633002900	helix-hairpin-helix signature motif; other site
880633002901	substrate binding pocket [chemical binding]; other site
880633002902	active site
880633002903	potential frameshift: common BLAST hit: gi|315039225|ref|YP_004032793.1| transposase
880633002904	LytTr DNA-binding domain; Region: LytTR; smart00850
880633002905	Protein of unknown function (DUF3021); Region: DUF3021; pfam11457
880633002906	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
880633002907	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
880633002908	Coenzyme A binding pocket [chemical binding]; other site
880633002909	Transposase; Region: DEDD_Tnp_IS110; pfam01548
880633002910	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
880633002911	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
880633002912	Predicted transcriptional regulators [Transcription]; Region: COG1733
880633002913	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
880633002914	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
880633002915	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
880633002916	Beta-lactamase; Region: Beta-lactamase; pfam00144
880633002917	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
880633002918	dipeptidase PepV; Reviewed; Region: PRK07318
880633002919	M20 Peptidase Xaa-His dipeptidase (PepV) degrades hydrophobic dipeptides; Region: M20_PepV; cd03888
880633002920	active site
880633002921	metal binding site [ion binding]; metal-binding site
880633002922	potential frameshift: common BLAST hit: gi|295693693|ref|YP_003602303.1| glycolate oxidase
880633002923	potential frameshift: common BLAST hit: gi|295693693|ref|YP_003602303.1| glycolate oxidase
880633002924	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
880633002925	potential frameshift: common BLAST hit: gi|381335637|ref|YP_005202604.1| threonine dehydrogenase related Zn-dependent dehydrogenase
880633002926	hypothetical protein; Provisional; Region: PRK06194
880633002927	classical (c) SDRs; Region: SDR_c; cd05233
880633002928	NAD(P) binding site [chemical binding]; other site
880633002929	active site
880633002930	Nitroreductase-like family 1. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_1; cd02137
880633002931	dimer interface [polypeptide binding]; other site
880633002932	FMN binding site [chemical binding]; other site
880633002933	Transcriptional regulator [Transcription]; Region: LysR; COG0583
880633002934	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
880633002935	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
880633002936	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
880633002937	3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme metabolism]; Region: UbiX; COG0163
880633002938	Flavoprotein; Region: Flavoprotein; pfam02441
880633002939	potential frameshift: common BLAST hit: gi|385813775|ref|YP_005850168.1| 3-polyprenyl-4-hydroxybenzoate decarboxylase related decarboxylase
880633002940	potential frameshift: common BLAST hit: gi|389867622|ref|YP_006375045.1| integral membrane protein
880633002941	Branched-chain amino acid transport protein; Region: Branch_AA_trans; cl00547
880633002942	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
880633002943	pyridoxal 5'-phosphate binding site [chemical binding]; other site
880633002944	homodimer interface [polypeptide binding]; other site
880633002945	catalytic residue [active]
880633002946	Predicted membrane-bound metal-dependent hydrolase (DUF457); Region: DUF457; pfam04307
880633002947	Replication initiator protein A (RepA) N-terminus; Region: RepA_N; pfam06970
880633002948	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
880633002949	active site
880633002950	potential frameshift: common BLAST hit: gi|385813784|ref|YP_005850177.1| MFS superfamily major facilitator transporter
880633002951	potential frameshift: common BLAST hit: gi|385813784|ref|YP_005850177.1| MFS superfamily major facilitator transporter
880633002952	Bacterial surface layer protein; Region: SLAP; pfam03217
880633002953	pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK07251
880633002954	TrkA-N domain; Region: TrkA_N; pfam02254
880633002955	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
880633002956	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
880633002957	Uncharacterized conserved protein (DUF2075); Region: DUF2075; pfam09848
880633002958	AAA ATPase domain; Region: AAA_16; pfam13191
880633002959	Walker A motif; other site
880633002960	ATP binding site [chemical binding]; other site
880633002961	Walker B motif; other site
880633002962	Uncharacterized conserved protein [Function unknown]; Region: COG3410
880633002963	potential frameshift: common BLAST hit: gi|295692931|ref|YP_003601541.1| amino acid permease
880633002964	L-type amino acid transporter; Region: 2A0308; TIGR00911
880633002965	Amino acid transporters [Amino acid transport and metabolism]; Region: LysP; COG0833
880633002966	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
880633002967	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
880633002968	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
880633002969	active site
880633002970	Zn binding site [ion binding]; other site
880633002971	Acetokinase family; Region: Acetate_kinase; cl17229
880633002972	Regulator of G protein signaling (RGS) domain superfamily; Region: RGS; cl02565
880633002973	Transposase, Mutator family; Region: Transposase_mut; pfam00872
880633002974	Transposase, Mutator family; Region: Transposase_mut; pfam00872
880633002975	MULE transposase domain; Region: MULE; pfam10551
880633002976	daunorubicin resistance ABC transporter ATP-binding subunit; Region: drrA; TIGR01188
880633002977	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
880633002978	Walker A/P-loop; other site
880633002979	ATP binding site [chemical binding]; other site
880633002980	Q-loop/lid; other site
880633002981	ABC transporter signature motif; other site
880633002982	Walker B; other site
880633002983	D-loop; other site
880633002984	H-loop/switch region; other site
880633002985	thiazole/oxazole-forming peptide maturase, SagD family component; Region: TOMM_cyclo_SagD; TIGR03604
880633002986	potential frameshift: common BLAST hit: gi|161507599|ref|YP_001577553.1| transposase IS1201
880633002987	potential frameshift: common BLAST hit: gi|161508084|ref|YP_001578051.1| transposase IS1201
880633002988	YcaO-like family; Region: YcaO; pfam02624
880633002989	thiazole/oxazole-forming peptide maturase, SagC family component; Region: cyclo_dehy_ocin; TIGR03603
880633002990	This family is the oxydase domain of NRPS (non-ribosomal peptide synthetase) and other proteins that modify polypeptides by cyclizing a thioester to form a ring. These include epoB, part of the epothilone biosynthesis pathway; tubD, part of the tubulysin...; Region: mcbC-like_oxidoreductase; cd02142
880633002991	NADPH bind site [chemical binding]; other site
880633002992	putative FMN binding site [chemical binding]; other site
880633002993	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
880633002994	Bacillus subtilis YhcR endonuclease and related proteins, N-terminal metallophosphatase domain; Region: MPP_YhcR_N; cd07412
880633002995	putative active site [active]
880633002996	putative metal binding site [ion binding]; other site
880633002997	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
880633002998	Bacterial surface layer protein; Region: SLAP; pfam03217
880633002999	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
880633003000	DDE superfamily endonuclease; Region: DDE_5; cl17874
880633003001	Domain of unknown function (DUF4016); Region: DUF4016; pfam13208
880633003002	TIGR02687 family protein; Region: TIGR02687
880633003003	PglZ domain; Region: PglZ; pfam08665
880633003004	AAA ATPase domain; Region: AAA_16; pfam13191
880633003005	AAA domain; Region: AAA_22; pfam13401
880633003006	AAA domain; Region: AAA_14; pfam13173
880633003007	Domain of unknown function (DUF1788); Region: DUF1788; pfam08747
880633003008	Putative inner membrane protein (DUF1819); Region: DUF1819; pfam08849
880633003009	Uncharacterized conserved protein [Function unknown]; Region: COG1479
880633003010	Protein of unknown function DUF262; Region: DUF262; pfam03235
880633003011	Protein of unknown function DUF262; Region: DUF262; pfam03235
880633003012	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
880633003013	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
880633003014	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
880633003015	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
880633003016	ligand binding site [chemical binding]; other site
880633003017	flexible hinge region; other site
880633003018	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
880633003019	putative switch regulator; other site
880633003020	non-specific DNA interactions [nucleotide binding]; other site
880633003021	DNA binding site [nucleotide binding]
880633003022	sequence specific DNA binding site [nucleotide binding]; other site
880633003023	putative cAMP binding site [chemical binding]; other site
880633003024	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cl00264
880633003025	dinuclear metal binding motif [ion binding]; other site
880633003026	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
880633003027	metal-binding site [ion binding]
880633003028	heavy metal translocating P-type ATPase; Region: ATPase-IB_hvy; TIGR01525
880633003029	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
880633003030	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
880633003031	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
880633003032	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
880633003033	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
880633003034	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
880633003035	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
880633003036	Predicted transcriptional regulator [Transcription]; Region: COG2378
880633003037	HTH domain; Region: HTH_11; pfam08279
880633003038	WYL domain; Region: WYL; pfam13280
880633003039	Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381
880633003040	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_2; cd07253
880633003041	dimer interface [polypeptide binding]; other site
880633003042	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
880633003043	metal binding site [ion binding]; metal-binding site
880633003044	ASC-1 homology or ASCH domain, a small beta-barrel domain found in all three kingdoms of life. ASCH resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as an RNA-binding domain during coactivation; Region: ASCH; cl01020
880633003045	Peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: MsrA; COG0225
880633003046	SH3-like domain; Region: SH3_8; pfam13457
880633003047	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
880633003048	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
880633003049	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
880633003050	Ca binding site [ion binding]; other site
880633003051	active site
880633003052	catalytic site [active]
880633003053	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
880633003054	DNA-binding site [nucleotide binding]; DNA binding site
880633003055	trehalose operon repressor, B. subtilis-type; Region: trehalos_R_Bsub; TIGR02404
880633003056	UTRA domain; Region: UTRA; pfam07702
880633003057	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
880633003058	HPr interaction site; other site
880633003059	glycerol kinase (GK) interaction site [polypeptide binding]; other site
880633003060	active site
880633003061	phosphorylation site [posttranslational modification]
880633003062	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
880633003063	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
880633003064	active site turn [active]
880633003065	phosphorylation site [posttranslational modification]
880633003066	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
880633003067	potential frameshift: common BLAST hit: gi|385812926|ref|YP_005849319.1| Transposase, IS30 family
880633003068	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
880633003069	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
880633003070	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
880633003071	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
880633003072	Probable transposase; Region: OrfB_IS605; pfam01385
880633003073	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
880633003074	Predicted site-specific integrase-resolvase [DNA replication, recombination, and repair]; Region: COG2452
880633003075	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
880633003076	DNA binding residues [nucleotide binding]
880633003077	Serine Recombinase (SR) family, IS607-like transposase subfamily, catalytic domain; members contain a DNA binding domain with homology to MerR/SoxR located N-terminal to the catalytic domain. Serine recombinases catalyze site-specific recombination of...; Region: SR_IS607_transposase_like; cd03769
880633003078	catalytic residues [active]
880633003079	catalytic nucleophile [active]
880633003080	Protein of unknown function (DUF3021); Region: DUF3021; pfam11457
880633003081	LytTr DNA-binding domain; Region: LytTR; smart00850
880633003082	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
880633003083	active site
880633003084	dimerization interface [polypeptide binding]; other site
880633003085	Protein of unknown function (DUF3923); Region: DUF3923; pfam13061
880633003086	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
880633003087	Walker A/P-loop; other site
880633003088	ATP binding site [chemical binding]; other site
880633003089	Q-loop/lid; other site
880633003090	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
880633003091	ABC transporter signature motif; other site
880633003092	Walker B; other site
880633003093	D-loop; other site
880633003094	H-loop/switch region; other site
880633003095	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
880633003096	AAA domain; Region: AAA_21; pfam13304
880633003097	Walker A/P-loop; other site
880633003098	ATP binding site [chemical binding]; other site
880633003099	Q-loop/lid; other site
880633003100	ABC transporter signature motif; other site
880633003101	Walker B; other site
880633003102	D-loop; other site
880633003103	H-loop/switch region; other site
880633003104	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
880633003105	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
880633003106	Coenzyme A binding pocket [chemical binding]; other site
880633003107	Helix-Turn-Helix DNA binding domain of BmrR-like transcription regulators; Region: HTH_BmrR-like; cd04768
880633003108	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
880633003109	DNA binding residues [nucleotide binding]
880633003110	drug binding residues [chemical binding]; other site
880633003111	dimer interface [polypeptide binding]; other site
880633003112	Plasmid encoded toxin Txe; Region: Plasmid_Txe; cl17389
880633003113	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041; cl17396
880633003114	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
880633003115	potential frameshift: common BLAST hit: gi|385813975|ref|YP_005850368.1| transposase
880633003116	potential frameshift: common BLAST hit: gi|385813771|ref|YP_005850164.1| DNA integrase
880633003117	potential frameshift: common BLAST hit: gi|385813445|ref|YP_005849838.1| Transposase ISLhe15
880633003118	potential frameshift: common BLAST hit: gi|161507702|ref|YP_001577658.1| transposase
880633003119	Hydrolase of X-linked nucleoside diphosphate N terminal; Region: Nudix_N; pfam12535
880633003120	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_14; cd04672
880633003121	nudix motif; other site
880633003122	Phosphorylase superfamily; Region: PNP_UDP_1; pfam01048
880633003123	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
880633003124	active site
880633003125	catalytic motif [active]
880633003126	Zn binding site [ion binding]; other site
880633003127	potential frameshift: common BLAST hit: gi|315039225|ref|YP_004032793.1| transposase
880633003128	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
880633003129	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
880633003130	Coenzyme A binding pocket [chemical binding]; other site
880633003131	Probable transposase; Region: OrfB_IS605; pfam01385
880633003132	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
880633003133	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
880633003134	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
880633003135	H+ Antiporter protein; Region: 2A0121; TIGR00900
880633003136	putative substrate translocation pore; other site
880633003137	potential frameshift: common BLAST hit: gi|385813887|ref|YP_005850280.1| Filamentation induced by cAMP protein Fic
880633003138	potential frameshift: common BLAST hit: gi|336054613|ref|YP_004562900.1| transposase
880633003139	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
880633003140	Protein of unknown function (DUF1304); Region: DUF1304; pfam06993
880633003141	Domain of unknown function (DUF4097); Region: DUF4097; pfam13349
880633003142	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
880633003143	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
880633003144	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
880633003145	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
880633003146	Walker A/P-loop; other site
880633003147	ATP binding site [chemical binding]; other site
880633003148	Q-loop/lid; other site
880633003149	ABC transporter signature motif; other site
880633003150	Walker B; other site
880633003151	D-loop; other site
880633003152	H-loop/switch region; other site
880633003153	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
880633003154	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
880633003155	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
880633003156	Walker A/P-loop; other site
880633003157	ATP binding site [chemical binding]; other site
880633003158	Q-loop/lid; other site
880633003159	ABC transporter signature motif; other site
880633003160	Walker B; other site
880633003161	D-loop; other site
880633003162	H-loop/switch region; other site
880633003163	Fic/DOC family; Region: Fic; cl00960
880633003164	Fic/DOC family; Region: Fic; cl00960
880633003165	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
880633003166	peptidase T; Region: peptidase-T; TIGR01882
880633003167	metal binding site [ion binding]; metal-binding site
880633003168	dimer interface [polypeptide binding]; other site
880633003169	potential frameshift: common BLAST hit: gi|385813896|ref|YP_005850289.1| Membrane protein
880633003170	Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229
880633003171	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
880633003172	ECF-type riboflavin transporter, S component; Region: ECF-ribofla_trS; cl17272
880633003173	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
880633003174	pyridoxal binding site [chemical binding]; other site
880633003175	dimer interface [polypeptide binding]; other site
880633003176	ATP binding site [chemical binding]; other site
880633003177	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
880633003178	Beta-lactamase; Region: Beta-lactamase; pfam00144
880633003179	maltose O-acetyltransferase; Provisional; Region: PRK10092
880633003180	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
880633003181	active site
880633003182	substrate binding site [chemical binding]; other site
880633003183	trimer interface [polypeptide binding]; other site
880633003184	CoA binding site [chemical binding]; other site
880633003185	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
880633003186	active site
880633003187	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
880633003188	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
880633003189	ATP-dependent DNA helicase RecQ; Region: recQ; TIGR01389
880633003190	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
880633003191	ATP binding site [chemical binding]; other site
880633003192	putative Mg++ binding site [ion binding]; other site
880633003193	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
880633003194	nucleotide binding region [chemical binding]; other site
880633003195	ATP-binding site [chemical binding]; other site
880633003196	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
880633003197	HRDC domain; Region: HRDC; pfam00570
880633003198	Cation transport protein; Region: TrkH; cl17365
880633003199	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
880633003200	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
880633003201	Cation transport protein; Region: TrkH; cl17365
880633003202	potential frameshift: common BLAST hit: gi|58337294|ref|YP_193879.1| NAD+ binding protein for K+transport
880633003203	Cystathionine beta-lyase family protein involved in aluminum resistance [Inorganic ion transport and metabolism]; Region: COG4100
880633003204	Aluminium resistance protein; Region: Alum_res; pfam06838
880633003205	putative ornithine decarboxylase; Region: lacto_ODC_hypo; TIGR04318
880633003206	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
880633003207	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
880633003208	catalytic residue [active]
880633003209	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
880633003210	Amino acid permease; Region: AA_permease_2; pfam13520
880633003211	camphor resistance protein CrcB; Provisional; Region: PRK14220
880633003212	Integral membrane protein possibly involved in chromosome condensation [Cell division and chromosome partitioning]; Region: CrcB; COG0239
880633003213	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
880633003214	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
880633003215	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
880633003216	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
880633003217	potential frameshift: common BLAST hit: gi|315038560|ref|YP_004032128.1| transposase ORF_C
880633003218	potential frameshift: common BLAST hit: gi|315038560|ref|YP_004032128.1| transposase ORF_C
880633003219	potential frameshift: common BLAST hit: gi|315038558|ref|YP_004032126.1| transposase ORF_A
880633003220	Aldose 1-epimerase, similar to Lactococcus lactis lacX; Region: Aldose_epim_lacX; cd09024
880633003221	active site
880633003222	catalytic residues [active]
880633003223	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
880633003224	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
880633003225	Walker A motif; other site
880633003226	ATP binding site [chemical binding]; other site
880633003227	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
880633003228	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
880633003229	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
880633003230	active site
880633003231	HslU subunit interaction site [polypeptide binding]; other site
880633003232	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
880633003233	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
880633003234	active site
880633003235	DNA binding site [nucleotide binding]
880633003236	Int/Topo IB signature motif; other site
880633003237	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
880633003238	Glucose inhibited division protein A; Region: GIDA; pfam01134
880633003239	DNA topoisomerase I; Validated; Region: PRK05582
880633003240	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
880633003241	active site
880633003242	interdomain interaction site; other site
880633003243	putative metal-binding site [ion binding]; other site
880633003244	nucleotide binding site [chemical binding]; other site
880633003245	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
880633003246	domain I; other site
880633003247	DNA binding groove [nucleotide binding]
880633003248	phosphate binding site [ion binding]; other site
880633003249	domain II; other site
880633003250	domain III; other site
880633003251	nucleotide binding site [chemical binding]; other site
880633003252	catalytic site [active]
880633003253	domain IV; other site
880633003254	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
880633003255	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
880633003256	DNA protecting protein DprA; Region: dprA; TIGR00732
880633003257	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
880633003258	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
880633003259	RNA/DNA hybrid binding site [nucleotide binding]; other site
880633003260	active site
880633003261	ribosome biogenesis GTP-binding protein YlqF; Region: GTPase_YlqF; TIGR03596
880633003262	Circularly permuted YlqF GTPase; Region: YlqF; cd01856
880633003263	GTP/Mg2+ binding site [chemical binding]; other site
880633003264	G4 box; other site
880633003265	G5 box; other site
880633003266	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
880633003267	G1 box; other site
880633003268	G1 box; other site
880633003269	GTP/Mg2+ binding site [chemical binding]; other site
880633003270	Switch I region; other site
880633003271	G2 box; other site
880633003272	G2 box; other site
880633003273	Switch I region; other site
880633003274	G3 box; other site
880633003275	G3 box; other site
880633003276	Switch II region; other site
880633003277	Switch II region; other site
880633003278	G4 box; other site
880633003279	potential frameshift: common BLAST hit: gi|161507468|ref|YP_001577422.1| Na+/H+ antiporter
880633003280	hypothetical protein; Provisional; Region: PRK13672
880633003281	EDD domain protein, DegV family; Region: DegV; TIGR00762
880633003282	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
880633003283	Predicted membrane protein, hemolysin III homolog [General function prediction only]; Region: COG1272
880633003284	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
880633003285	tRNA CCA-pyrophosphorylase; Provisional; Region: PRK13299
880633003286	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
880633003287	active site
880633003288	NTP binding site [chemical binding]; other site
880633003289	metal binding triad [ion binding]; metal-binding site
880633003290	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
880633003291	tRNA nucleotidyltransferase domain 2 putative; Region: tRNA_NucTran2_2; pfam13735
880633003292	Uncharacterized conserved protein [Function unknown]; Region: COG1284
880633003293	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
880633003294	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
880633003295	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
880633003296	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
880633003297	binding surface
880633003298	TPR motif; other site
880633003299	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
880633003300	IHF dimer interface [polypeptide binding]; other site
880633003301	IHF - DNA interface [nucleotide binding]; other site
880633003302	GTP-binding protein Der; Reviewed; Region: PRK00093
880633003303	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
880633003304	G1 box; other site
880633003305	GTP/Mg2+ binding site [chemical binding]; other site
880633003306	Switch I region; other site
880633003307	G2 box; other site
880633003308	Switch II region; other site
880633003309	G3 box; other site
880633003310	G4 box; other site
880633003311	G5 box; other site
880633003312	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
880633003313	G1 box; other site
880633003314	GTP/Mg2+ binding site [chemical binding]; other site
880633003315	Switch I region; other site
880633003316	G2 box; other site
880633003317	G3 box; other site
880633003318	Switch II region; other site
880633003319	G4 box; other site
880633003320	G5 box; other site
880633003321	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06676
880633003322	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
880633003323	RNA binding site [nucleotide binding]; other site
880633003324	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
880633003325	RNA binding site [nucleotide binding]; other site
880633003326	S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692
880633003327	RNA binding site [nucleotide binding]; other site
880633003328	cytidylate kinase; Provisional; Region: cmk; PRK00023
880633003329	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
880633003330	CMP-binding site; other site
880633003331	The sites determining sugar specificity; other site
880633003332	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
880633003333	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
880633003334	Predicted membrane protein [Function unknown]; Region: COG3601
880633003335	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
880633003336	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
880633003337	RNA binding surface [nucleotide binding]; other site
880633003338	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
880633003339	active site
880633003340	segregation and condensation protein B; Reviewed; Region: scpB; PRK00135
880633003341	segregation and condensation protein A; Reviewed; Region: scpA; PRK00104
880633003342	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
880633003343	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
880633003344	active site
880633003345	Int/Topo IB signature motif; other site
880633003346	Predicted RNA-bindining protein (contains S1 and HTH domains) [General function prediction only]; Region: COG2996
880633003347	S1 domain; Region: S1_2; pfam13509
880633003348	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
880633003349	RNA binding site [nucleotide binding]; other site
880633003350	MarR family; Region: MarR_2; pfam12802
880633003351	pyruvate kinase; Provisional; Region: PRK06354
880633003352	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
880633003353	domain interfaces; other site
880633003354	active site
880633003355	Phosphohistidine swiveling domain [Signal transduction mechanisms]; Region: COG3848
880633003356	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
880633003357	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
880633003358	active site
880633003359	ADP/pyrophosphate binding site [chemical binding]; other site
880633003360	dimerization interface [polypeptide binding]; other site
880633003361	allosteric effector site; other site
880633003362	fructose-1,6-bisphosphate binding site; other site
880633003363	DNA polymerase III, alpha subunit [DNA replication, recombination, and repair]; Region: DnaE; COG0587
880633003364	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III; Region: PHP_PolIIIA; cd07431
880633003365	active site
880633003366	PHP Thumb interface [polypeptide binding]; other site
880633003367	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
880633003368	generic binding surface I; other site
880633003369	generic binding surface II; other site
880633003370	Protein of unknown function (DUF2929); Region: DUF2929; pfam11151
880633003371	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
880633003372	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
880633003373	active site
880633003374	metal binding site [ion binding]; metal-binding site
880633003375	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
880633003376	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
880633003377	Protein of unknown function (DUF1049); Region: DUF1049; cl01539
880633003378	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
880633003379	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
880633003380	NAD(P) binding site [chemical binding]; other site
880633003381	active site
880633003382	ribonuclease Z; Region: RNase_Z; TIGR02651
880633003383	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
880633003384	yrhL-like subfamily of SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_yrhL_like; cd01840
880633003385	catalytic triad [active]
880633003386	catalytic triad [active]
880633003387	oxyanion hole [active]
880633003388	GTPase CgtA; Reviewed; Region: obgE; PRK12297
880633003389	GTP1/OBG; Region: GTP1_OBG; pfam01018
880633003390	Obg GTPase; Region: Obg; cd01898
880633003391	G1 box; other site
880633003392	GTP/Mg2+ binding site [chemical binding]; other site
880633003393	Switch I region; other site
880633003394	G2 box; other site
880633003395	G3 box; other site
880633003396	Switch II region; other site
880633003397	G4 box; other site
880633003398	G5 box; other site
880633003399	Domain of unknown function (DUF1967); Region: DUF1967; pfam09269
880633003400	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
880633003401	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
880633003402	GIY-YIG motif/motif A; other site
880633003403	active site
880633003404	catalytic site [active]
880633003405	putative DNA binding site [nucleotide binding]; other site
880633003406	metal binding site [ion binding]; metal-binding site
880633003407	UvrB/uvrC motif; Region: UVR; pfam02151
880633003408	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
880633003409	H3TH domains of structure-specific 5' nucleases (or flap endonuclease-1-like) involved in DNA replication, repair, and recombination; Region: H3TH_StructSpec-5'-nucleases; cl14815
880633003410	DNA binding site [nucleotide binding]
880633003411	potential frameshift: common BLAST hit: gi|161507431|ref|YP_001577385.1| alkaline phosphatase
880633003412	amino acid transporter; Region: 2A0306; TIGR00909
880633003413	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
880633003414	potential frameshift: common BLAST hit: gi|315038174|ref|YP_004031742.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein
880633003415	sugar phosphate phosphatase; Provisional; Region: PRK10513
880633003416	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
880633003417	active site
880633003418	motif I; other site
880633003419	motif II; other site
880633003420	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
880633003421	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
880633003422	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
880633003423	active site
880633003424	catalytic tetrad [active]
880633003425	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
880633003426	MULE transposase domain; Region: MULE; pfam10551
880633003427	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
880633003428	Flavoprotein; Region: Flavoprotein; pfam02441
880633003429	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
880633003430	aromatic amino acid aminotransferase; Validated; Region: PRK07309
880633003431	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
880633003432	pyridoxal 5'-phosphate binding site [chemical binding]; other site
880633003433	homodimer interface [polypeptide binding]; other site
880633003434	catalytic residue [active]
880633003435	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
880633003436	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
880633003437	dimer interface [polypeptide binding]; other site
880633003438	anticodon binding site; other site
880633003439	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
880633003440	homodimer interface [polypeptide binding]; other site
880633003441	motif 1; other site
880633003442	active site
880633003443	motif 2; other site
880633003444	GAD domain; Region: GAD; pfam02938
880633003445	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
880633003446	active site
880633003447	motif 3; other site
880633003448	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
880633003449	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
880633003450	dimer interface [polypeptide binding]; other site
880633003451	motif 1; other site
880633003452	active site
880633003453	motif 2; other site
880633003454	motif 3; other site
880633003455	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
880633003456	anticodon binding site; other site
880633003457	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
880633003458	putative active site [active]
880633003459	dimerization interface [polypeptide binding]; other site
880633003460	putative tRNAtyr binding site [nucleotide binding]; other site
880633003461	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
880633003462	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
880633003463	Zn2+ binding site [ion binding]; other site
880633003464	Mg2+ binding site [ion binding]; other site
880633003465	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
880633003466	synthetase active site [active]
880633003467	NTP binding site [chemical binding]; other site
880633003468	metal binding site [ion binding]; metal-binding site
880633003469	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
880633003470	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
880633003471	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
880633003472	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
880633003473	S-adenosylmethionine binding site [chemical binding]; other site
880633003474	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
880633003475	putative deacylase active site [active]
880633003476	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
880633003477	substrate binding site [chemical binding]; other site
880633003478	Uncharacterized conserved protein [Function unknown]; Region: COG2966
880633003479	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
880633003480	Protein of unknown function (DUF3815); Region: DUF3815; pfam12821
880633003481	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
880633003482	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
880633003483	Domain of unknown function DUF1828; Region: DUF1828; pfam08861
880633003484	hypothetical protein; Provisional; Region: PRK13661
880633003485	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
880633003486	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
880633003487	Walker A/P-loop; other site
880633003488	ATP binding site [chemical binding]; other site
880633003489	Q-loop/lid; other site
880633003490	ABC transporter signature motif; other site
880633003491	Walker B; other site
880633003492	D-loop; other site
880633003493	H-loop/switch region; other site
880633003494	ATP-binding cassette cobalt transporter; Region: DUF3744; pfam12558
880633003495	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
880633003496	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
880633003497	Walker A/P-loop; other site
880633003498	ATP binding site [chemical binding]; other site
880633003499	Q-loop/lid; other site
880633003500	ABC transporter signature motif; other site
880633003501	Walker B; other site
880633003502	D-loop; other site
880633003503	H-loop/switch region; other site
880633003504	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
880633003505	Protein of unknown function (DUF441); Region: DUF441; pfam04284
880633003506	Transposase, Mutator family; Region: Transposase_mut; pfam00872
880633003507	MULE transposase domain; Region: MULE; pfam10551
880633003508	Protein of unknown function (DUF1706); Region: DUF1706; pfam08020
880633003509	choice-of-anchor A domain; Region: choice_anch_A; TIGR04215
880633003510	potential frameshift: common BLAST hit: gi|161508084|ref|YP_001578051.1| transposase IS1201
880633003511	potential frameshift: common BLAST hit: gi|161506703|ref|YP_001576653.1| transposase IS1201
880633003512	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
880633003513	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
880633003514	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
880633003515	citrate lyase subunit gamma; Provisional; Region: PRK13253
880633003516	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
880633003517	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
880633003518	putative active site [active]
880633003519	(T/H)XGH motif; other site
880633003520	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
880633003521	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
880633003522	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
880633003523	transmembrane helices; other site
880633003524	Peptidase C1B subfamily (MEROPS database nomenclature); composed of eukaryotic bleomycin hydrolases (BH) and bacterial aminopeptidases C (pepC). The proteins of this subfamily contain a large insert relative to the C1A peptidase (papain) subfamily. BH is...; Region: Peptidase_C1B; cd00585
880633003525	trimer interface [polypeptide binding]; other site
880633003526	active site
880633003527	G bulge; other site
880633003528	potential frameshift: common BLAST hit: gi|336054263|ref|YP_004562550.1| mucus binding protein
880633003529	Uncharacterized protein family (UPF0236); Region: UPF0236; pfam06782
880633003530	potential frameshift: common BLAST hit: gi|385813445|ref|YP_005849838.1| Transposase ISLhe15
880633003531	L-lactate dehydrogenase; Reviewed; Region: ldh; PRK00066
880633003532	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
880633003533	tetramer (dimer of dimers) interface [polypeptide binding]; other site
880633003534	NAD binding site [chemical binding]; other site
880633003535	dimer interface [polypeptide binding]; other site
880633003536	substrate binding site [chemical binding]; other site
880633003537	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
880633003538	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
880633003539	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
880633003540	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
880633003541	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
880633003542	L-aspartate oxidase; Provisional; Region: PRK06175
880633003543	flavocytochrome c; Region: flavo_cyto_c; TIGR01813
880633003544	Predicted oxidoreductase [General function prediction only]; Region: COG3573
880633003545	fumarate hydratase; Reviewed; Region: fumC; PRK00485
880633003546	Class II fumarases; Region: Fumarase_classII; cd01362
880633003547	active site
880633003548	tetramer interface [polypeptide binding]; other site
880633003549	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
880633003550	dimer interface [polypeptide binding]; other site
880633003551	conserved gate region; other site
880633003552	ABC-ATPase subunit interface; other site
880633003553	ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism]; Region: AbcC; COG1135
880633003554	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
880633003555	Walker A/P-loop; other site
880633003556	ATP binding site [chemical binding]; other site
880633003557	Q-loop/lid; other site
880633003558	ABC transporter signature motif; other site
880633003559	Walker B; other site
880633003560	D-loop; other site
880633003561	H-loop/switch region; other site
880633003562	NIL domain; Region: NIL; pfam09383
880633003563	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
880633003564	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
880633003565	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
880633003566	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
880633003567	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
880633003568	motif I; other site
880633003569	motif II; other site
880633003570	potential frameshift: common BLAST hit: gi|58337642|ref|YP_194227.1| transcriptional regulator phage-related
880633003571	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
880633003572	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
880633003573	folate binding site [chemical binding]; other site
880633003574	NADP+ binding site [chemical binding]; other site
880633003575	thymidylate synthase; Region: thym_sym; TIGR03284
880633003576	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
880633003577	dimerization interface [polypeptide binding]; other site
880633003578	active site
880633003579	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
880633003580	Uncharacterized protein family (UPF0150); Region: UPF0150; pfam03681
880633003581	potential frameshift: common BLAST hit: gi|385817471|ref|YP_005853861.1| choloylglycine hydrolase
880633003582	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
880633003583	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
880633003584	active site
880633003585	EDD domain protein, DegV family; Region: DegV; TIGR00762
880633003586	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
880633003587	enolase; Provisional; Region: eno; PRK00077
880633003588	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
880633003589	dimer interface [polypeptide binding]; other site
880633003590	metal binding site [ion binding]; metal-binding site
880633003591	substrate binding pocket [chemical binding]; other site
880633003592	Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer,  utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cd02062
880633003593	FMN binding site [chemical binding]; other site
880633003594	dimer interface [polypeptide binding]; other site
880633003595	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
880633003596	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
880633003597	DNA-binding site [nucleotide binding]; DNA binding site
880633003598	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
880633003599	potential frameshift: common BLAST hit: gi|315038123|ref|YP_004031691.1| 6-phospho-beta-glucosidase
880633003600	Domain of unknown function (DUF3284); Region: DUF3284; pfam11687
880633003601	Protein of unknown function (DUF4065); Region: DUF4065; pfam13274
880633003602	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
880633003603	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
880633003604	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
880633003605	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
880633003606	Transposase; Region: DEDD_Tnp_IS110; pfam01548
880633003607	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
880633003608	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
880633003609	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
880633003610	Transposase; Region: DDE_Tnp_ISL3; pfam01610
880633003611	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
880633003612	Transposase; Region: DDE_Tnp_ISL3; pfam01610
880633003613	Transposase; Region: DEDD_Tnp_IS110; pfam01548
880633003614	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
880633003615	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
880633003616	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
880633003617	active site
880633003618	methionine cluster; other site
880633003619	phosphorylation site [posttranslational modification]
880633003620	metal binding site [ion binding]; metal-binding site
880633003621	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
880633003622	active site
880633003623	P-loop; other site
880633003624	phosphorylation site [posttranslational modification]
880633003625	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
880633003626	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
880633003627	DNA-binding site [nucleotide binding]; DNA binding site
880633003628	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
880633003629	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
880633003630	beta-galactosidase; Region: BGL; TIGR03356
880633003631	potential frameshift: common BLAST hit: gi|295692434|ref|YP_003601044.1| oxidoreductase, aldo/keto reductase family
880633003632	potential frameshift: common BLAST hit: gi|295692434|ref|YP_003601044.1| oxidoreductase, aldo/keto reductase family
880633003633	potential frameshift: common BLAST hit: gi|385814031|ref|YP_005850424.1| Inosine-uridine preferring nucleoside hydrolase
880633003634	FMN-binding domain; Region: FMN_bind; cl01081
880633003635	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cd00741
880633003636	nucleophilic elbow; other site
880633003637	catalytic triad; other site
880633003638	Hydrolase of X-linked nucleoside diphosphate N terminal; Region: Nudix_N; pfam12535
880633003639	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_14; cd04672
880633003640	nudix motif; other site
880633003641	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
880633003642	Beta-lactamase; Region: Beta-lactamase; pfam00144
880633003643	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
880633003644	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
880633003645	aromatic amino acid aminotransferase; Validated; Region: PRK07309
880633003646	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
880633003647	pyridoxal 5'-phosphate binding site [chemical binding]; other site
880633003648	homodimer interface [polypeptide binding]; other site
880633003649	catalytic residue [active]
880633003650	dihydrodipicolinate reductase; Provisional; Region: PRK00048
880633003651	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
880633003652	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
880633003653	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
880633003654	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
880633003655	dimer interface [polypeptide binding]; other site
880633003656	active site
880633003657	catalytic residue [active]
880633003658	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
880633003659	M20 Peptidase Aminoacyclase-1 YkuR-like proteins, including YkuR and Ama/HipO/HyuC proteins; Region: M20_Acy1_YkuR_like; cd05670
880633003660	metal binding site [ion binding]; metal-binding site
880633003661	putative dimer interface [polypeptide binding]; other site
880633003662	Tetrahydrodipicolinate succinyltransferase N-terminal; Region: DapH_N; pfam08503
880633003663	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Region: DapD_Ac; TIGR03532
880633003664	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
880633003665	active site
880633003666	trimer interface [polypeptide binding]; other site
880633003667	substrate binding site [chemical binding]; other site
880633003668	CoA binding site [chemical binding]; other site
880633003669	diaminopimelate decarboxylase; Region: lysA; TIGR01048
880633003670	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
880633003671	active site
880633003672	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
880633003673	substrate binding site [chemical binding]; other site
880633003674	catalytic residues [active]
880633003675	dimer interface [polypeptide binding]; other site
880633003676	aspartate kinase; Reviewed; Region: PRK09034
880633003677	AAK_AKiii-YclM-BS: Amino Acid Kinase Superfamily (AAK), AKiii-YclM-BS; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII, a monofunctional class enzyme found in...; Region: AAK_AKiii-YclM-BS; cd04245
880633003678	putative catalytic residues [active]
880633003679	putative nucleotide binding site [chemical binding]; other site
880633003680	putative aspartate binding site [chemical binding]; other site
880633003681	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
880633003682	ACT domains located C-terminal to the catalytic domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-YclM-BS_2; cd04916
880633003683	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
880633003684	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
880633003685	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
880633003686	inner membrane transporter YjeM; Provisional; Region: PRK15238
880633003687	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
880633003688	G1 box; other site
880633003689	GTP/Mg2+ binding site [chemical binding]; other site
880633003690	Switch I region; other site
880633003691	G2 box; other site
880633003692	G3 box; other site
880633003693	Switch II region; other site
880633003694	G4 box; other site
880633003695	G5 box; other site
880633003696	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
880633003697	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
880633003698	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
880633003699	Walker A motif; other site
880633003700	ATP binding site [chemical binding]; other site
880633003701	Walker B motif; other site
880633003702	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
880633003703	trigger factor; Provisional; Region: tig; PRK01490
880633003704	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
880633003705	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
880633003706	elongation factor Tu; Reviewed; Region: PRK00049
880633003707	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
880633003708	G1 box; other site
880633003709	GEF interaction site [polypeptide binding]; other site
880633003710	GTP/Mg2+ binding site [chemical binding]; other site
880633003711	Switch I region; other site
880633003712	G2 box; other site
880633003713	G3 box; other site
880633003714	Switch II region; other site
880633003715	G4 box; other site
880633003716	G5 box; other site
880633003717	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
880633003718	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
880633003719	Antibiotic Binding Site [chemical binding]; other site
880633003720	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
880633003721	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
880633003722	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
880633003723	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
880633003724	16S/18S rRNA binding site [nucleotide binding]; other site
880633003725	S13e-L30e interaction site [polypeptide binding]; other site
880633003726	25S rRNA binding site [nucleotide binding]; other site
880633003727	Uncharacterized protein family (UPF0236); Region: UPF0236; pfam06782
880633003728	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
880633003729	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
880633003730	DNA polymerase III, delta subunit; Region: holA; TIGR01128
880633003731	Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658
880633003732	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
880633003733	Competence protein; Region: Competence; pfam03772
880633003734	Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333
880633003735	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
880633003736	SLBB domain; Region: SLBB; pfam10531
880633003737	comEA protein; Region: comE; TIGR01259
880633003738	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786
880633003739	Predicted secreted protein containing a PDZ domain [Signal transduction mechanisms]; Region: SdrC; COG3480
880633003740	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
880633003741	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
880633003742	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
880633003743	active site
880633003744	(T/H)XGH motif; other site
880633003745	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
880633003746	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
880633003747	S-adenosylmethionine binding site [chemical binding]; other site
880633003748	Uncharacterized protein conserved in bacteria (DUF2129); Region: DUF2129; pfam09902
880633003749	cell division protein FtsW; Region: ftsW; TIGR02614
880633003750	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
880633003751	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
880633003752	G1 box; other site
880633003753	putative GEF interaction site [polypeptide binding]; other site
880633003754	GTP/Mg2+ binding site [chemical binding]; other site
880633003755	Switch I region; other site
880633003756	G2 box; other site
880633003757	G3 box; other site
880633003758	Switch II region; other site
880633003759	G4 box; other site
880633003760	G5 box; other site
880633003761	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
880633003762	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
880633003763	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
880633003764	active site
880633003765	catalytic residues [active]
880633003766	metal binding site [ion binding]; metal-binding site
880633003767	hypothetical protein; Provisional; Region: PRK13667
880633003768	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
880633003769	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
880633003770	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
880633003771	potential frameshift: common BLAST hit: gi|325956522|ref|YP_004291934.1| transcriptional regulator
880633003772	Helix-turn-helix domain of transposase family ISL3; Region: HTH_Tnp_ISL3; pfam13542
880633003773	Transposase; Region: DDE_Tnp_ISL3; pfam01610
880633003774	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
880633003775	Transposase; Region: DDE_Tnp_ISL3; pfam01610
880633003776	Transposase; Region: DEDD_Tnp_IS110; pfam01548
880633003777	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
880633003778	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
880633003779	potential frameshift: common BLAST hit: gi|161507331|ref|YP_001577285.1| exodeoxyribonuclease V alpha chain
880633003780	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
880633003781	binding surface
880633003782	TPR motif; other site
880633003783	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
880633003784	catalytic core [active]
880633003785	tRNA methyl transferase; Region: tRNA_Me_trans; pfam03054
880633003786	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
880633003787	Putative amino acid metabolism; Region: DUF1831; pfam08866
880633003788	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
880633003789	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
880633003790	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
880633003791	catalytic residue [active]
880633003792	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
880633003793	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
880633003794	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
880633003795	dimer interface [polypeptide binding]; other site
880633003796	ADP-ribose binding site [chemical binding]; other site
880633003797	active site
880633003798	nudix motif; other site
880633003799	metal binding site [ion binding]; metal-binding site
880633003800	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
880633003801	DNA-binding site [nucleotide binding]; DNA binding site
880633003802	RNA-binding motif; other site
880633003803	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
880633003804	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
880633003805	active site
880633003806	HIGH motif; other site
880633003807	nucleotide binding site [chemical binding]; other site
880633003808	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
880633003809	active site
880633003810	KMSKS motif; other site
880633003811	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
880633003812	tRNA binding surface [nucleotide binding]; other site
880633003813	anticodon binding site; other site
880633003814	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
880633003815	DivIVA protein; Region: DivIVA; pfam05103
880633003816	DivIVA domain; Region: DivI1A_domain; TIGR03544
880633003817	Uncharacterized conserved protein, contains S4-like domain [Function unknown]; Region: COG2302
880633003818	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
880633003819	RNA binding surface [nucleotide binding]; other site
880633003820	YGGT family; Region: YGGT; pfam02325
880633003821	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1799
880633003822	cell division protein FtsZ; Validated; Region: PRK09330
880633003823	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
880633003824	nucleotide binding site [chemical binding]; other site
880633003825	SulA interaction site; other site
880633003826	Cell division ATPase FtsA [Cell division and chromosome partitioning]; Region: ftsA; COG0849
880633003827	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
880633003828	nucleotide binding site [chemical binding]; other site
880633003829	Cell division protein FtsA; Region: FtsA; cl17206
880633003830	Cell division protein FtsA; Region: FtsA; pfam14450
880633003831	Cell division protein FtsQ; Region: FtsQ; pfam03799
880633003832	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
880633003833	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
880633003834	active site
880633003835	homodimer interface [polypeptide binding]; other site
880633003836	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK02472
880633003837	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
880633003838	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
880633003839	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
880633003840	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
880633003841	Mg++ binding site [ion binding]; other site
880633003842	putative catalytic motif [active]
880633003843	putative substrate binding site [chemical binding]; other site
880633003844	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
880633003845	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
880633003846	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
880633003847	PASTA domain of PBP2x-like proteins, first repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_1; cd06576
880633003848	PASTA domain of PBP2x-like proteins, second repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_2; cd06575
880633003849	Cell division protein FtsL; Region: FtsL; cl11433
880633003850	MraW methylase family; Region: Methyltransf_5; pfam01795
880633003851	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
880633003852	cell division protein MraZ; Reviewed; Region: PRK00326
880633003853	MraZ protein; Region: MraZ; pfam02381
880633003854	MraZ protein; Region: MraZ; pfam02381
880633003855	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
880633003856	Protein of unknown function (DUF4044); Region: DUF4044; pfam13253
880633003857	rod shape-determining protein MreD; Region: shape_MreD; TIGR03426
880633003858	rod shape-determining protein MreC; Provisional; Region: PRK13922
880633003859	rod shape-determining protein MreC; Region: MreC; pfam04085
880633003860	rod shape-determining protein MreB; Provisional; Region: PRK13927
880633003861	MreB and similar proteins; Region: MreB_like; cd10225
880633003862	nucleotide binding site [chemical binding]; other site
880633003863	Mg binding site [ion binding]; other site
880633003864	putative protofilament interaction site [polypeptide binding]; other site
880633003865	RodZ interaction site [polypeptide binding]; other site
880633003866	DNA repair protein radc; Region: radc; TIGR00608
880633003867	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
880633003868	MPN+ (JAMM) motif; other site
880633003869	Zinc-binding site [ion binding]; other site
880633003870	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
880633003871	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
880633003872	motif II; other site
880633003873	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
880633003874	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
880633003875	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
880633003876	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
880633003877	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
880633003878	active site
880633003879	HIGH motif; other site
880633003880	nucleotide binding site [chemical binding]; other site
880633003881	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
880633003882	active site
880633003883	KMSKS motif; other site
880633003884	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
880633003885	tRNA binding surface [nucleotide binding]; other site
880633003886	anticodon binding site; other site
880633003887	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
880633003888	Toxin ToxN, type III toxin-antitoxin system; Region: ToxN_toxin; pfam13958
880633003889	potential frameshift: common BLAST hit: gi|336054366|ref|YP_004562653.1| cell division protein
880633003890	potential frameshift: common BLAST hit: gi|385814102|ref|YP_005850495.1| cell division protein
880633003891	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
880633003892	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
880633003893	Ligand binding site; other site
880633003894	Putative Catalytic site; other site
880633003895	DXD motif; other site
880633003896	Predicted membrane protein [Function unknown]; Region: COG2246
880633003897	GtrA-like protein; Region: GtrA; pfam04138
880633003898	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
880633003899	Glycerophosphodiester phosphodiesterase domain as found in prokaryota and eukaryota, and similar proteins; Region: GDPD; cd08556
880633003900	active site
880633003901	catalytic site [active]
880633003902	metal binding site [ion binding]; metal-binding site
880633003903	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
880633003904	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
880633003905	potential frameshift: common BLAST hit: gi|385814112|ref|YP_005850505.1| XRE family transcriptional regulator
880633003906	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
880633003907	salt bridge; other site
880633003908	non-specific DNA binding site [nucleotide binding]; other site
880633003909	sequence-specific DNA binding site [nucleotide binding]; other site
880633003910	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
880633003911	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
880633003912	RNA binding surface [nucleotide binding]; other site
880633003913	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
880633003914	active site
880633003915	uracil binding [chemical binding]; other site
880633003916	thiamine biosynthesis protein ThiI; Provisional; Region: PRK01565
880633003917	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
880633003918	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
880633003919	Ligand Binding Site [chemical binding]; other site
880633003920	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
880633003921	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
880633003922	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
880633003923	catalytic residue [active]
880633003924	septation ring formation regulator EzrA; Provisional; Region: PRK04778
880633003925	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
880633003926	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
880633003927	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
880633003928	RNA binding surface [nucleotide binding]; other site
880633003929	Protein of unknown function (DUF1694); Region: DUF1694; pfam07997
880633003930	recombination factor protein RarA; Reviewed; Region: PRK13342
880633003931	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
880633003932	Walker A motif; other site
880633003933	ATP binding site [chemical binding]; other site
880633003934	Walker B motif; other site
880633003935	arginine finger; other site
880633003936	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
880633003937	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
880633003938	Ligand Binding Site [chemical binding]; other site
880633003939	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
880633003940	Protein of unknown function (DUF2969); Region: DUF2969; pfam11184
880633003941	hypothetical protein; Provisional; Region: PRK14379
880633003942	rod shape-determining protein MreB; Provisional; Region: PRK13930
880633003943	MreB and similar proteins; Region: MreB_like; cd10225
880633003944	nucleotide binding site [chemical binding]; other site
880633003945	Mg binding site [ion binding]; other site
880633003946	putative protofilament interaction site [polypeptide binding]; other site
880633003947	RodZ interaction site [polypeptide binding]; other site
880633003948	Protein of unknown function (DUF1146); Region: DUF1146; cl11486
880633003949	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
880633003950	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
880633003951	gamma subunit interface [polypeptide binding]; other site
880633003952	epsilon subunit interface [polypeptide binding]; other site
880633003953	LBP interface [polypeptide binding]; other site
880633003954	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
880633003955	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
880633003956	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
880633003957	alpha subunit interaction interface [polypeptide binding]; other site
880633003958	Walker A motif; other site
880633003959	ATP binding site [chemical binding]; other site
880633003960	Walker B motif; other site
880633003961	inhibitor binding site; inhibition site
880633003962	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
880633003963	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
880633003964	core domain interface [polypeptide binding]; other site
880633003965	delta subunit interface [polypeptide binding]; other site
880633003966	epsilon subunit interface [polypeptide binding]; other site
880633003967	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
880633003968	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
880633003969	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
880633003970	beta subunit interaction interface [polypeptide binding]; other site
880633003971	Walker A motif; other site
880633003972	ATP binding site [chemical binding]; other site
880633003973	Walker B motif; other site
880633003974	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
880633003975	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
880633003976	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
880633003977	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
880633003978	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
880633003979	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
880633003980	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
880633003981	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
880633003982	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
880633003983	active site
880633003984	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
880633003985	Putative GTP-binding controlling metal-binding; Region: SUA5; pfam03481
880633003986	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
880633003987	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
880633003988	S-adenosylmethionine binding site [chemical binding]; other site
880633003989	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
880633003990	peptide chain release factor 1; Validated; Region: prfA; PRK00591
880633003991	This domain is found in peptide chain release factors; Region: PCRF; smart00937
880633003992	RF-1 domain; Region: RF-1; pfam00472
880633003993	thymidine kinase; Provisional; Region: PRK04296
880633003994	UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurE; COG0769
880633003995	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
880633003996	Domain of unknown function (DUF1727); Region: DUF1727; pfam08353
880633003997	Beta-lactamase; Region: Beta-lactamase; pfam00144
880633003998	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
880633003999	potential frameshift: common BLAST hit: gi|325956450|ref|YP_004291862.1| multi-drug-type permease
880633004000	potential frameshift: common BLAST hit: gi|385817340|ref|YP_005853730.1| multi-drug-type permease
880633004001	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14097
880633004002	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
880633004003	active site
880633004004	dimer interface [polypeptide binding]; other site
880633004005	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
880633004006	dimer interface [polypeptide binding]; other site
880633004007	active site
880633004008	VanZ like family; Region: VanZ; pfam04892
880633004009	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
880633004010	Sulfatase; Region: Sulfatase; pfam00884
880633004011	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
880633004012	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
880633004013	dimerization interface [polypeptide binding]; other site
880633004014	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
880633004015	dimer interface [polypeptide binding]; other site
880633004016	phosphorylation site [posttranslational modification]
880633004017	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
880633004018	ATP binding site [chemical binding]; other site
880633004019	Mg2+ binding site [ion binding]; other site
880633004020	G-X-G motif; other site
880633004021	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
880633004022	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
880633004023	active site
880633004024	phosphorylation site [posttranslational modification]
880633004025	intermolecular recognition site; other site
880633004026	dimerization interface [polypeptide binding]; other site
880633004027	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
880633004028	DNA binding site [nucleotide binding]
880633004029	SdpI/YhfL protein family; Region: SdpI; pfam13630
880633004030	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
880633004031	mannose-6-phosphate isomerase, class I; Region: manA; TIGR00218
880633004032	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
880633004033	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
880633004034	pyridoxal 5'-phosphate binding site [chemical binding]; other site
880633004035	homodimer interface [polypeptide binding]; other site
880633004036	catalytic residue [active]
880633004037	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
880633004038	propionate/acetate kinase; Provisional; Region: PRK12379
880633004039	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827
880633004040	Methyltransferase domain; Region: Methyltransf_26; pfam13659
880633004041	CobN/Magnesium Chelatase; Region: CobN-Mg_chel; pfam02514
880633004042	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
880633004043	Competence protein ComGC [Intracellular trafficking and secretion]; Region: ComGC; COG4537
880633004044	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
880633004045	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
880633004046	Type II/IV secretion system protein; Region: T2SE; pfam00437
880633004047	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
880633004048	Walker A motif; other site
880633004049	ATP binding site [chemical binding]; other site
880633004050	Walker B motif; other site
880633004051	hypothetical protein; Validated; Region: PRK00110
880633004052	Predicted integral membrane protein [Function unknown]; Region: COG5652
880633004053	Amino acid permease; Region: AA_permease_2; pfam13520
880633004054	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
880633004055	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
880633004056	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
880633004057	beta-galactosidase; Region: BGL; TIGR03356
880633004058	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
880633004059	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
880633004060	active site turn [active]
880633004061	phosphorylation site [posttranslational modification]
880633004062	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
880633004063	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
880633004064	HPr interaction site; other site
880633004065	glycerol kinase (GK) interaction site [polypeptide binding]; other site
880633004066	active site
880633004067	phosphorylation site [posttranslational modification]
880633004068	transcriptional antiterminator BglG; Provisional; Region: PRK09772
880633004069	CAT RNA binding domain; Region: CAT_RBD; smart01061
880633004070	PRD domain; Region: PRD; pfam00874
880633004071	PRD domain; Region: PRD; pfam00874
880633004072	glycerate kinase; Region: TIGR00045
880633004073	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
880633004074	Low molecular weight phosphatase family; Region: LMWPc; cd00115
880633004075	active site
880633004076	clostripain; Region: clostrip; TIGR02806
880633004077	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
880633004078	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
880633004079	active site
880633004080	motif I; other site
880633004081	motif II; other site
880633004082	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
880633004083	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
880633004084	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
880633004085	active site
880633004086	motif I; other site
880633004087	motif II; other site
880633004088	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
880633004089	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14316
880633004090	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
880633004091	active site
880633004092	substrate binding site [chemical binding]; other site
880633004093	metal binding site [ion binding]; metal-binding site
880633004094	YbbR-like protein; Region: YbbR; pfam07949
880633004095	YbbR-like protein; Region: YbbR; pfam07949
880633004096	YbbR-like protein; Region: YbbR; pfam07949
880633004097	Uncharacterized conserved protein [Function unknown]; Region: COG1624
880633004098	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
880633004099	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
880633004100	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
880633004101	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
880633004102	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
880633004103	dimer interface [polypeptide binding]; other site
880633004104	conserved gate region; other site
880633004105	putative PBP binding loops; other site
880633004106	ABC-ATPase subunit interface; other site
880633004107	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
880633004108	dimer interface [polypeptide binding]; other site
880633004109	conserved gate region; other site
880633004110	putative PBP binding loops; other site
880633004111	ABC-ATPase subunit interface; other site
880633004112	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
880633004113	ATP-binding cassette domain of the polyamine transporter; Region: ABC_PotA_N; cd03300
880633004114	Walker A/P-loop; other site
880633004115	ATP binding site [chemical binding]; other site
880633004116	Q-loop/lid; other site
880633004117	ABC transporter signature motif; other site
880633004118	Walker B; other site
880633004119	D-loop; other site
880633004120	H-loop/switch region; other site
880633004121	TOBE domain; Region: TOBE_2; pfam08402
880633004122	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
880633004123	FAD binding domain; Region: FAD_binding_4; pfam01565
880633004124	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
880633004125	an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III; Region: DNA_pol_III_epsilon_like; cd06130
880633004126	active site
880633004127	catalytic site [active]
880633004128	substrate binding site [chemical binding]; other site
880633004129	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
880633004130	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
880633004131	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
880633004132	ligand binding site [chemical binding]; other site
880633004133	active site
880633004134	UGI interface [polypeptide binding]; other site
880633004135	catalytic site [active]
880633004136	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
880633004137	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
880633004138	active site
880633004139	motif I; other site
880633004140	motif II; other site
880633004141	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
880633004142	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
880633004143	triosephosphate isomerase; Provisional; Region: PRK14567
880633004144	substrate binding site [chemical binding]; other site
880633004145	dimer interface [polypeptide binding]; other site
880633004146	catalytic triad [active]
880633004147	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
880633004148	Phosphoglycerate kinase; Region: PGK; pfam00162
880633004149	substrate binding site [chemical binding]; other site
880633004150	hinge regions; other site
880633004151	ADP binding site [chemical binding]; other site
880633004152	catalytic site [active]
880633004153	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
880633004154	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
880633004155	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
880633004156	Predicted transcriptional regulator [Transcription]; Region: COG3388
880633004157	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
880633004158	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
880633004159	potential frameshift: common BLAST hit: gi|295692567|ref|YP_003601177.1| conserved protein with bacterial ig-like domain
880633004160	potential frameshift: common BLAST hit: gi|295692567|ref|YP_003601177.1| conserved protein with bacterial ig-like domain
880633004161	inner membrane transporter YjeM; Provisional; Region: PRK15238
880633004162	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
880633004163	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
880633004164	active site
880633004165	motif I; other site
880633004166	motif II; other site
880633004167	SH3-like domain; Region: SH3_8; pfam13457
880633004168	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
880633004169	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
880633004170	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
880633004171	oligomer interface [polypeptide binding]; other site
880633004172	active site residues [active]
880633004173	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1481
880633004174	Sporulation Regulator WhiA N terminal; Region: WhiA_N; pfam10298
880633004175	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
880633004176	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
880633004177	putative substrate binding pocket [chemical binding]; other site
880633004178	dimer interface [polypeptide binding]; other site
880633004179	phosphate binding site [ion binding]; other site
880633004180	glmZ(sRNA)-inactivating NTPase; Provisional; Region: PRK05416
880633004181	Uncharacterized conserved protein [Function unknown]; Region: HdeD; COG3247
880633004182	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
880633004183	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
880633004184	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
880633004185	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
880633004186	excinuclease ABC subunit B; Provisional; Region: PRK05298
880633004187	Myosin and Kinesin motor domain. These ATPases belong to the P-loop NTPase family and provide the driving force in myosin and kinesin mediated processes; Region: Motor_domain; cl00286
880633004188	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
880633004189	ATP-binding site [chemical binding]; other site
880633004190	ATP binding site [chemical binding]; other site
880633004191	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
880633004192	nucleotide binding region [chemical binding]; other site
880633004193	ATP-binding site [chemical binding]; other site
880633004194	Ultra-violet resistance protein B; Region: UvrB; pfam12344
880633004195	UvrB/uvrC motif; Region: UVR; pfam02151
880633004196	phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150
880633004197	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
880633004198	active site
880633004199	substrate binding site [chemical binding]; other site
880633004200	metal binding site [ion binding]; metal-binding site
880633004201	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
880633004202	active site
880633004203	homodimer interface [polypeptide binding]; other site
880633004204	catalytic site [active]
880633004205	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
880633004206	glycogen/starch/alpha-glucan phosphorylases; Region: P_ylase; TIGR02093
880633004207	active site pocket [active]
880633004208	glycogen synthase; Provisional; Region: glgA; PRK00654
880633004209	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
880633004210	ADP-binding pocket [chemical binding]; other site
880633004211	homodimer interface [polypeptide binding]; other site
880633004212	glucose-1-phosphate adenylyltransferase, GlgD subunit; Region: glgD; TIGR02092
880633004213	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
880633004214	active site
880633004215	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
880633004216	dimer interface [polypeptide binding]; other site
880633004217	N-terminal domain interface [polypeptide binding]; other site
880633004218	sulfate 1 binding site; other site
880633004219	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK05293
880633004220	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
880633004221	ligand binding site; other site
880633004222	oligomer interface; other site
880633004223	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
880633004224	dimer interface [polypeptide binding]; other site
880633004225	N-terminal domain interface [polypeptide binding]; other site
880633004226	sulfate 1 binding site; other site
880633004227	glycogen branching enzyme; Provisional; Region: PRK12313
880633004228	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
880633004229	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
880633004230	active site
880633004231	catalytic site [active]
880633004232	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
880633004233	potential frameshift: common BLAST hit: gi|385812926|ref|YP_005849319.1| Transposase, IS30 family
880633004234	potential frameshift: common BLAST hit: gi|336053291|ref|YP_004557983.1| transposase
880633004235	Transposase; Region: DEDD_Tnp_IS110; pfam01548
880633004236	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
880633004237	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
880633004238	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
880633004239	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
880633004240	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
880633004241	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK12437
880633004242	HPr kinase/phosphorylase; Provisional; Region: PRK05428
880633004243	HPr Serine kinase N terminus; Region: Hpr_kinase_N; pfam02603
880633004244	HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent...; Region: HprK_C; cd01918
880633004245	Hpr binding site; other site
880633004246	active site
880633004247	homohexamer subunit interaction site [polypeptide binding]; other site
880633004248	peptide chain release factor 2; Provisional; Region: PRK05589
880633004249	This domain is found in peptide chain release factors; Region: PCRF; smart00937
880633004250	RF-1 domain; Region: RF-1; pfam00472
880633004251	preprotein translocase subunit SecA; Reviewed; Region: secA; PRK12906
880633004252	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
880633004253	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
880633004254	nucleotide binding region [chemical binding]; other site
880633004255	ATP-binding site [chemical binding]; other site
880633004256	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
880633004257	30S subunit binding site; other site
880633004258	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
880633004259	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
880633004260	active site
880633004261	DEAD-like helicases superfamily; Region: DEXDc; smart00487
880633004262	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
880633004263	ATP binding site [chemical binding]; other site
880633004264	putative Mg++ binding site [ion binding]; other site
880633004265	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
880633004266	nucleotide binding region [chemical binding]; other site
880633004267	ATP-binding site [chemical binding]; other site
880633004268	Uncharacterized conserved protein [Function unknown]; Region: COG1739
880633004269	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
880633004270	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
880633004271	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
880633004272	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
880633004273	Mg++ binding site [ion binding]; other site
880633004274	putative catalytic motif [active]
880633004275	substrate binding site [chemical binding]; other site
880633004276	Helix-turn-helix domain of transposase family ISL3; Region: HTH_Tnp_ISL3; pfam13542
880633004277	Transposase; Region: DDE_Tnp_ISL3; pfam01610
880633004278	potential frameshift: common BLAST hit: gi|161507783|ref|YP_001577747.1| transposase
880633004279	phosphodiesterase; Provisional; Region: PRK12704
880633004280	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
880633004281	Zn2+ binding site [ion binding]; other site
880633004282	Mg2+ binding site [ion binding]; other site
880633004283	recombinase A; Provisional; Region: recA; PRK09354
880633004284	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
880633004285	hexamer interface [polypeptide binding]; other site
880633004286	Walker A motif; other site
880633004287	ATP binding site [chemical binding]; other site
880633004288	Walker B motif; other site
880633004289	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
880633004290	Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown]; Region: COG1426
880633004291	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
880633004292	non-specific DNA binding site [nucleotide binding]; other site
880633004293	salt bridge; other site
880633004294	sequence-specific DNA binding site [nucleotide binding]; other site
880633004295	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
880633004296	classical (c) SDRs; Region: SDR_c; cd05233
880633004297	NAD(P) binding site [chemical binding]; other site
880633004298	active site
880633004299	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
880633004300	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
880633004301	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
880633004302	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
880633004303	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
880633004304	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
880633004305	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
880633004306	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
880633004307	Protein of unknown function (DUF1149); Region: DUF1149; cl11551
880633004308	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
880633004309	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
880633004310	Domain of unknown function DUF20; Region: UPF0118; pfam01594
880633004311	PTS system glucitol/sorbitol-specific IIA component; Region: PTSIIA_gutA; cl01516
880633004312	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
880633004313	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
880633004314	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
880633004315	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
880633004316	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
880633004317	motif II; other site
880633004318	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
880633004319	Lactonase, 7-bladed beta-propeller; Region: Lactonase; pfam10282
880633004320	myosin-cross-reactive antigen; Provisional; Region: PRK13977
880633004321	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
880633004322	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
880633004323	active site
880633004324	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK04885
880633004325	ATP-NAD kinase; Region: NAD_kinase; pfam01513
880633004326	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
880633004327	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
880633004328	synthetase active site [active]
880633004329	NTP binding site [chemical binding]; other site
880633004330	metal binding site [ion binding]; metal-binding site
880633004331	Uncharacterized subgroup 1 of the CYTH-like superfamily; Region: CYTH-like_Pase_1; cd07762
880633004332	putative active site [active]
880633004333	putative metal binding residues [ion binding]; other site
880633004334	signature motif; other site
880633004335	putative triphosphate binding site [ion binding]; other site
880633004336	Thioredoxin; Region: Thioredoxin_5; pfam13743
880633004337	Competence protein CoiA-like family; Region: CoiA; cl11541
880633004338	adaptor protein; Provisional; Region: PRK02315
880633004339	Arsenate Reductase (ArsC) family, Spx subfamily; Spx is a unique RNA polymerase (RNAP)-binding protein present in bacilli and some mollicutes. It inhibits transcription by binding to the C-terminal domain of the alpha subunit of RNAP, disrupting complex...; Region: ArsC_Spx; cd03032
880633004340	ArsC family; Region: ArsC; pfam03960
880633004341	putative catalytic residues [active]
880633004342	thiol/disulfide switch; other site
880633004343	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
880633004344	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
880633004345	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
880633004346	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
880633004347	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
880633004348	dimerization domain swap beta strand [polypeptide binding]; other site
880633004349	regulatory protein interface [polypeptide binding]; other site
880633004350	active site
880633004351	regulatory phosphorylation site [posttranslational modification]; other site
880633004352	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
880633004353	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
880633004354	Walker A motif; other site
880633004355	ATP binding site [chemical binding]; other site
880633004356	Walker B motif; other site
880633004357	arginine finger; other site
880633004358	UvrB/uvrC motif; Region: UVR; pfam02151
880633004359	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
880633004360	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
880633004361	Walker A motif; other site
880633004362	ATP binding site [chemical binding]; other site
880633004363	Walker B motif; other site
880633004364	arginine finger; other site
880633004365	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
880633004366	Domain of unknown function (DUF1827); Region: DUF1827; pfam08860
880633004367	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
880633004368	Transposase; Region: DDE_Tnp_ISL3; pfam01610
880633004369	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
880633004370	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
880633004371	G1 box; other site
880633004372	putative GEF interaction site [polypeptide binding]; other site
880633004373	GTP/Mg2+ binding site [chemical binding]; other site
880633004374	Switch I region; other site
880633004375	G2 box; other site
880633004376	G3 box; other site
880633004377	Switch II region; other site
880633004378	G4 box; other site
880633004379	G5 box; other site
880633004380	Translation_Factor_II_like: Elongation factor Tu (EF-Tu) domain II-like proteins. Elongation factor Tu consists of three structural domains, this family represents the second domain. Domain II adopts a beta barrel structure and is involved in binding to...; Region: Translation_Factor_II_like; cl02787
880633004381	Putative Mg2+ and Co2+ transporter CorC [Inorganic ion transport and metabolism]; Region: CorC; COG4535
880633004382	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
880633004383	Transporter associated domain; Region: CorC_HlyC; pfam03471
880633004384	Flavoprotein; Region: Flavoprotein; cl08021
880633004385	recombination regulator RecX; Provisional; Region: recX; PRK14135
880633004386	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
880633004387	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
880633004388	S-adenosylmethionine binding site [chemical binding]; other site
880633004389	potential frameshift: common BLAST hit: gi|315039225|ref|YP_004032793.1| transposase
880633004390	potential frameshift: common BLAST hit: gi|336055445|ref|YP_004563731.1| resolvase
880633004391	potential frameshift: common BLAST hit: gi|385814303|ref|YP_005850696.1| Transposase, IS4 family
880633004392	3-hydroxy-3-methylglutaryl CoA synthase, prokaryotic clade; Region: HMG-CoA-S_prok; TIGR01835
880633004393	"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are...; Region: init_cond_enzymes; cd00827
880633004394	dimer interface [polypeptide binding]; other site
880633004395	active site
880633004396	Class II hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR); Region: HMG-CoA_reductase_classII; cd00644
880633004397	homodimer interface [polypeptide binding]; other site
880633004398	catalytic residues [active]
880633004399	NAD binding site [chemical binding]; other site
880633004400	substrate binding pocket [chemical binding]; other site
880633004401	flexible flap; other site
880633004402	putative acyltransferase; Provisional; Region: PRK05790
880633004403	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
880633004404	dimer interface [polypeptide binding]; other site
880633004405	active site
880633004406	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
880633004407	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
880633004408	active site
880633004409	tetramer interface; other site
880633004410	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
880633004411	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
880633004412	methionine aminopeptidase; Provisional; Region: PRK08671
880633004413	active site
880633004414	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
880633004415	Predicted membrane protein [Function unknown]; Region: COG2246
880633004416	GtrA-like protein; Region: GtrA; pfam04138
880633004417	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
880633004418	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
880633004419	active site
880633004420	homodimer interface [polypeptide binding]; other site
880633004421	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
880633004422	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
880633004423	DEAD-like helicases superfamily; Region: DEXDc; smart00487
880633004424	DEAD/DEAH box helicase; Region: DEAD; pfam00270
880633004425	ATP binding site [chemical binding]; other site
880633004426	putative Mg++ binding site [ion binding]; other site
880633004427	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
880633004428	nucleotide binding region [chemical binding]; other site
880633004429	ATP-binding site [chemical binding]; other site
880633004430	Endo-N-acetylmuramidases (muramidases) are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues; Region: GH25_muramidase; cl10448
880633004431	active site
880633004432	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
880633004433	amino acid transporter; Region: 2A0306; TIGR00909
880633004434	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
880633004435	active site
880633004436	Domain of unknown function DUF21; Region: DUF21; pfam01595
880633004437	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
880633004438	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
880633004439	Transporter associated domain; Region: CorC_HlyC; smart01091
880633004440	potential frameshift: common BLAST hit: gi|58336936|ref|YP_193521.1| nitroreductase
880633004441	potential frameshift: common BLAST hit: gi|385817194|ref|YP_005853584.1| nitroreductase
880633004442	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
880633004443	HPr interaction site; other site
880633004444	glycerol kinase (GK) interaction site [polypeptide binding]; other site
880633004445	active site
880633004446	phosphorylation site [posttranslational modification]
880633004447	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
880633004448	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
880633004449	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
880633004450	putative active site [active]
880633004451	PTS system, alpha-glucoside-specific IIBC component; Region: PTS-IIBC-alpha; TIGR02005
880633004452	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
880633004453	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
880633004454	active site turn [active]
880633004455	phosphorylation site [posttranslational modification]
880633004456	Phosphotransferase system IIB components [Carbohydrate transport and metabolism]; Region: PtsG; COG1264
880633004457	active site turn [active]
880633004458	phosphorylation site [posttranslational modification]
880633004459	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
880633004460	active site
880633004461	motif I; other site
880633004462	motif II; other site
880633004463	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
880633004464	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
880633004465	active site
880633004466	nucleophile elbow; other site
880633004467	putative phosphoketolase; Provisional; Region: PRK05261
880633004468	XFP N-terminal domain; Region: XFP_N; pfam09364
880633004469	XFP C-terminal domain; Region: XFP_C; pfam09363
880633004470	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
880633004471	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
880633004472	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
880633004473	Enterocin A Immunity; Region: EntA_Immun; pfam08951
880633004474	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
880633004475	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814; cl03223
880633004476	FeS assembly protein SufB; Region: sufB; TIGR01980
880633004477	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
880633004478	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
880633004479	trimerization site [polypeptide binding]; other site
880633004480	active site
880633004481	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
880633004482	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
880633004483	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
880633004484	catalytic residue [active]
880633004485	Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]; Region: SufB; COG0719
880633004486	FeS assembly protein SufD; Region: sufD; TIGR01981
880633004487	FeS assembly ATPase SufC; Region: sufC; TIGR01978
880633004488	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
880633004489	Walker A/P-loop; other site
880633004490	ATP binding site [chemical binding]; other site
880633004491	Q-loop/lid; other site
880633004492	ABC transporter signature motif; other site
880633004493	Walker B; other site
880633004494	D-loop; other site
880633004495	H-loop/switch region; other site
880633004496	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
880633004497	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
880633004498	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
880633004499	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
880633004500	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
880633004501	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
880633004502	DNA-binding site [nucleotide binding]; DNA binding site
880633004503	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
880633004504	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
880633004505	active site
880633004506	tetramer interface [polypeptide binding]; other site
880633004507	K+ potassium transporter; Region: K_trans; pfam02705
880633004508	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
880633004509	tetramer (dimer of dimers) interface [polypeptide binding]; other site
880633004510	active site
880633004511	dimer interface [polypeptide binding]; other site
880633004512	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
880633004513	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
880633004514	substrate binding site [chemical binding]; other site
880633004515	dimer interface [polypeptide binding]; other site
880633004516	ATP binding site [chemical binding]; other site
880633004517	HIT family: HIT (Histidine triad) proteins, named for a motif related to the sequence HxHxH/Qxx (x, a hydrophobic amino acid), are a superfamily of nucleotide hydrolases and transferases, which act on the alpha-phosphate of ribonucleotides. On the basis...; Region: HIT_like; cl00228
880633004518	nucleotide binding site/active site [active]
880633004519	HIT family signature motif; other site
880633004520	catalytic residue [active]
880633004521	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
880633004522	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
880633004523	Protein of unknown function (DUF2974); Region: DUF2974; pfam11187
880633004524	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
880633004525	dimer interface [polypeptide binding]; other site
880633004526	conserved gate region; other site
880633004527	putative PBP binding loops; other site
880633004528	ABC-ATPase subunit interface; other site
880633004529	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
880633004530	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
880633004531	dimer interface [polypeptide binding]; other site
880633004532	conserved gate region; other site
880633004533	putative PBP binding loops; other site
880633004534	ABC-ATPase subunit interface; other site
880633004535	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
880633004536	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
880633004537	substrate binding pocket [chemical binding]; other site
880633004538	membrane-bound complex binding site; other site
880633004539	hinge residues; other site
880633004540	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
880633004541	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
880633004542	Walker A/P-loop; other site
880633004543	ATP binding site [chemical binding]; other site
880633004544	Q-loop/lid; other site
880633004545	ABC transporter signature motif; other site
880633004546	Walker B; other site
880633004547	D-loop; other site
880633004548	H-loop/switch region; other site
880633004549	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
880633004550	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
880633004551	Probable transposase; Region: OrfB_IS605; pfam01385
880633004552	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
880633004553	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
880633004554	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
880633004555	Sugar specificity; other site
880633004556	Pyrimidine base specificity; other site
880633004557	ATP-binding site [chemical binding]; other site
880633004558	MFS/sugar transport protein; Region: MFS_2; pfam13347
880633004559	ABC-type cobalt transport system, permease component; Region: ABC_cobalt; pfam09819
880633004560	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
880633004561	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
880633004562	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
880633004563	Walker A/P-loop; other site
880633004564	ATP binding site [chemical binding]; other site
880633004565	Q-loop/lid; other site
880633004566	ABC transporter signature motif; other site
880633004567	Walker B; other site
880633004568	D-loop; other site
880633004569	H-loop/switch region; other site
880633004570	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
880633004571	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
880633004572	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
880633004573	Walker A/P-loop; other site
880633004574	ATP binding site [chemical binding]; other site
880633004575	Q-loop/lid; other site
880633004576	ABC transporter signature motif; other site
880633004577	Walker B; other site
880633004578	D-loop; other site
880633004579	H-loop/switch region; other site
880633004580	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
880633004581	Transcriptional regulators [Transcription]; Region: MarR; COG1846
880633004582	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
880633004583	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
880633004584	substrate binding pocket [chemical binding]; other site
880633004585	membrane-bound complex binding site; other site
880633004586	hinge residues; other site
880633004587	GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518
880633004588	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
880633004589	catalytic triad [active]
880633004590	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
880633004591	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
880633004592	Walker A/P-loop; other site
880633004593	ATP binding site [chemical binding]; other site
880633004594	Q-loop/lid; other site
880633004595	ABC transporter signature motif; other site
880633004596	Walker B; other site
880633004597	D-loop; other site
880633004598	H-loop/switch region; other site
880633004599	ABC transporter; Region: ABC_tran_2; pfam12848
880633004600	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
880633004601	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
880633004602	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
880633004603	oligomer interface [polypeptide binding]; other site
880633004604	active site
880633004605	metal binding site [ion binding]; metal-binding site
880633004606	drug efflux system protein MdtG; Provisional; Region: PRK09874
880633004607	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
880633004608	putative substrate translocation pore; other site
880633004609	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
880633004610	Major Facilitator Superfamily; Region: MFS_1; pfam07690
880633004611	putative substrate translocation pore; other site
880633004612	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
880633004613	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
880633004614	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
880633004615	active site
880633004616	uracil transporter; Provisional; Region: PRK10720
880633004617	Sulfate transporter family; Region: Sulfate_transp; pfam00916
880633004618	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
880633004619	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
880633004620	active site
880633004621	catalytic tetrad [active]
880633004622	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
880633004623	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
880633004624	Probable transposase; Region: OrfB_IS605; pfam01385
880633004625	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
880633004626	Piccolo Zn-finger; Region: zf-piccolo; pfam05715
880633004627	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cl00470
880633004628	Bacterial surface layer protein; Region: SLAP; pfam03217
880633004629	potential frameshift: common BLAST hit: gi|385813070|ref|YP_005849463.1| Putative transcriptional regulator
880633004630	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
880633004631	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
880633004632	Coenzyme A binding pocket [chemical binding]; other site
880633004633	myosin-cross-reactive antigen; Provisional; Region: PRK13977
880633004634	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
880633004635	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
880633004636	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
880633004637	putative substrate translocation pore; other site
880633004638	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
880633004639	Coenzyme A binding pocket [chemical binding]; other site
880633004640	Phycobilisome Linker polypeptide; Region: PBS_linker_poly; pfam00427
880633004641	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
880633004642	DNA-binding site [nucleotide binding]; DNA binding site
880633004643	RNA-binding motif; other site
880633004644	TRAM domain; Region: TRAM; cl01282
880633004645	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
880633004646	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
880633004647	S-adenosylmethionine binding site [chemical binding]; other site
880633004648	Na+/H+ antiporter NhaC; Region: antiport_nhaC; TIGR00931
880633004649	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
880633004650	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
880633004651	putative lipid kinase; Reviewed; Region: PRK13337
880633004652	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
880633004653	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
880633004654	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
880633004655	GatB domain; Region: GatB_Yqey; pfam02637
880633004656	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
880633004657	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
880633004658	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
880633004659	N-terminal repeat domain of CamS sex pheromone cAM373 precursor; Region: CamS_repeat_1; cd13441
880633004660	putative dimer interface [polypeptide binding]; other site
880633004661	CamS sex pheromone cAM373 precursor; Region: CamS; pfam07537
880633004662	C-terminal repeat domain of CamS sex pheromone cAM373 precursor; Region: CamS_repeat_2; cd13440
880633004663	putative dimer interface [polypeptide binding]; other site
880633004664	potential frameshift: common BLAST hit: gi|161507068|ref|YP_001577022.1| DNA ligase
880633004665	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
880633004666	Part of AAA domain; Region: AAA_19; pfam13245
880633004667	Family description; Region: UvrD_C_2; pfam13538
880633004668	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
880633004669	hypothetical protein; Provisional; Region: PRK04351
880633004670	SprT homologues; Region: SprT; cl01182
880633004671	Glycosyltransferase sugar-binding region containing DXD motif; Region: Gly_transf_sug; pfam04488
880633004672	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
880633004673	Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128
880633004674	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; Region: Glyphos_transf; pfam04464
880633004675	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
880633004676	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
880633004677	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
880633004678	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
880633004679	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
880633004680	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
880633004681	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
880633004682	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
880633004683	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
880633004684	homodimer interface [polypeptide binding]; other site
880633004685	NAD binding pocket [chemical binding]; other site
880633004686	ATP binding pocket [chemical binding]; other site
880633004687	Mg binding site [ion binding]; other site
880633004688	active-site loop [active]
880633004689	nicotinate phosphoribosyltransferase; Validated; Region: PRK09243
880633004690	Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction...; Region: NAPRTase_A; cd01570
880633004691	active site
880633004692	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
880633004693	This family is most closely related to the GT1 family of glycosyltransferases. wlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core; Region: GT1_wlbH_like; cd03798
880633004694	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
880633004695	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
880633004696	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
880633004697	Probable transposase; Region: OrfB_IS605; pfam01385
880633004698	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
880633004699	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
880633004700	Piccolo Zn-finger; Region: zf-piccolo; pfam05715
880633004701	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
880633004702	active site
880633004703	nucleotide binding site [chemical binding]; other site
880633004704	HIGH motif; other site
880633004705	KMSKS motif; other site
880633004706	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
880633004707	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
880633004708	DNA-binding site [nucleotide binding]; DNA binding site
880633004709	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
880633004710	potential protein location (hypothetical protein R0052_09220 [Lactobacillus helveticus R0052]) that overlaps RNA (tRNA-Y)
880633004711	Helix-turn-helix domain of transposase family ISL3; Region: HTH_Tnp_ISL3; pfam13542
880633004712	potential frameshift: common BLAST hit: gi|58336839|ref|YP_193424.1| regulatory protein
880633004713	potential frameshift: common BLAST hit: gi|295692365|ref|YP_003600975.1| sucrose phosphorylase
880633004714	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
880633004715	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
880633004716	active site
880633004717	catalytic site [active]
880633004718	Uncharacterized conserved protein [Function unknown]; Region: COG1359
880633004719	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
880633004720	catalytic core [active]
880633004721	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
880633004722	catalytic core [active]
880633004723	SEC10/PgrA surface exclusion domain; Region: Surf_Exclu_PgrA; TIGR04320
880633004724	Uncharacterized protein family (UPF0236); Region: UPF0236; pfam06782
880633004725	phosphoprotein phosphatases of the metallophosphatase superfamily, metallophosphatase domain; Region: MPP_PPP_family; cd00144
880633004726	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
880633004727	active site
880633004728	metal binding site [ion binding]; metal-binding site
880633004729	potential frameshift: common BLAST hit: gi|385814532|ref|YP_005850925.1| Transposase IS607 family
880633004730	potential frameshift: common BLAST hit: gi|385814532|ref|YP_005850925.1| Transposase IS607 family
880633004731	potential frameshift: common BLAST hit: gi|385814532|ref|YP_005850925.1| Transposase IS607 family
880633004732	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
880633004733	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
880633004734	active site
880633004735	dimer interface [polypeptide binding]; other site
880633004736	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
880633004737	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
880633004738	DNA-binding site [nucleotide binding]; DNA binding site
880633004739	UTRA domain; Region: UTRA; pfam07702
880633004740	TIGR02452 family protein; Region: TIGR02452
880633004741	Uncharacterized protein conserved in bacteria (DUF2263); Region: DUF2263; pfam10021
880633004742	CRISPR-associated helicase Cas3, subtype CYANO; Region: cas3_cyano; TIGR03158
880633004743	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
880633004744	ATP binding site [chemical binding]; other site
880633004745	putative Mg++ binding site [ion binding]; other site
880633004746	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
880633004747	nucleotide binding region [chemical binding]; other site
880633004748	ATP-binding site [chemical binding]; other site
880633004749	P-loop Domain of unknown function (DUF2791); Region: DUF2791; pfam10923
880633004750	AAA ATPase domain; Region: AAA_16; pfam13191
880633004751	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_HprK; cl00270
880633004752	active site
880633004753	metal-binding site [ion binding]
880633004754	nucleotide-binding site [chemical binding]; other site
880633004755	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_HprK; cl00270
880633004756	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Ap4A hydrolases are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_human_like; cd03428
880633004757	active site
880633004758	Ap4A binding cleft/pocket [chemical binding]; other site
880633004759	P4 phosphate binding site; other site
880633004760	nudix motif; other site
880633004761	putative P2/P3 phosphate binding site [ion binding]; other site
880633004762	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
880633004763	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
880633004764	propionate/acetate kinase; Provisional; Region: PRK12379
880633004765	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
880633004766	potential frameshift: common BLAST hit: gi|116628821|ref|YP_813993.1| adhesion exoprotein
880633004767	Amino acid permease; Region: AA_permease_2; pfam13520
880633004768	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
880633004769	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
880633004770	glutaminase active site [active]
880633004771	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
880633004772	dimer interface [polypeptide binding]; other site
880633004773	active site
880633004774	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
880633004775	dimer interface [polypeptide binding]; other site
880633004776	active site
880633004777	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
880633004778	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
880633004779	putative catalytic cysteine [active]
880633004780	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
880633004781	putative active site [active]
880633004782	metal binding site [ion binding]; metal-binding site
880633004783	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
880633004784	Spore germination protein; Region: Spore_permease; cl17796
880633004785	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
880633004786	putative trimer interface [polypeptide binding]; other site
880633004787	putative CoA binding site [chemical binding]; other site
880633004788	potential frameshift: common BLAST hit: gi|58336791|ref|YP_193376.1| transcriptional regulator
880633004789	potential frameshift: common BLAST hit: gi|58336791|ref|YP_193376.1| transcriptional regulator
880633004790	Domain of unknown function (DUF956); Region: DUF956; pfam06115
880633004791	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
880633004792	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
880633004793	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
880633004794	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
880633004795	active pocket/dimerization site; other site
880633004796	active site
880633004797	phosphorylation site [posttranslational modification]
880633004798	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
880633004799	active site
880633004800	phosphorylation site [posttranslational modification]
880633004801	seryl-tRNA synthetase; Provisional; Region: PRK05431
880633004802	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
880633004803	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
880633004804	dimer interface [polypeptide binding]; other site
880633004805	active site
880633004806	motif 1; other site
880633004807	motif 2; other site
880633004808	motif 3; other site
880633004809	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
880633004810	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
880633004811	Uncharacterized conserved protein [Function unknown]; Region: COG0398
880633004812	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
880633004813	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
880633004814	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
880633004815	non-specific DNA binding site [nucleotide binding]; other site
880633004816	salt bridge; other site
880633004817	sequence-specific DNA binding site [nucleotide binding]; other site
880633004818	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
880633004819	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
880633004820	NAD(P) binding site [chemical binding]; other site
880633004821	catalytic residues [active]
880633004822	Double zinc ribbon; Region: DZR; pfam12773
880633004823	zinc-ribbon domain; Region: zinc_ribbon_2; pfam13240
880633004824	MMPL family; Region: MMPL; pfam03176
880633004825	X-X-X-Leu-X-X-Gly heptad repeats; Region: xxxLxxG_by_4; TIGR03057
880633004826	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
880633004827	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
880633004828	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
880633004829	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
880633004830	uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u2; cd12827
880633004831	Cl binding site [ion binding]; other site
880633004832	oligomer interface [polypeptide binding]; other site
880633004833	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
880633004834	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
880633004835	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
880633004836	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
880633004837	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
880633004838	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
880633004839	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
880633004840	dimer interface [polypeptide binding]; other site
880633004841	conserved gate region; other site
880633004842	ABC-ATPase subunit interface; other site
880633004843	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
880633004844	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
880633004845	dimer interface [polypeptide binding]; other site
880633004846	conserved gate region; other site
880633004847	putative PBP binding loops; other site
880633004848	ABC-ATPase subunit interface; other site
880633004849	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
880633004850	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
880633004851	Walker A/P-loop; other site
880633004852	ATP binding site [chemical binding]; other site
880633004853	Q-loop/lid; other site
880633004854	ABC transporter signature motif; other site
880633004855	Walker B; other site
880633004856	D-loop; other site
880633004857	H-loop/switch region; other site
880633004858	TOBE domain; Region: TOBE_2; pfam08402
880633004859	Peptidase family C69; Region: Peptidase_C69; pfam03577
880633004860	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
880633004861	DNA/RNA non-specific endonuclease; Region: Endonuclea_NS_2; cl17626
880633004862	DNA polymerase III subunit epsilon; Validated; Region: PRK06195
880633004863	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
880633004864	active site
880633004865	catalytic site [active]
880633004866	substrate binding site [chemical binding]; other site
880633004867	NAD-dependent protein deacetylases, SIR2 family [Transcription]; Region: SIR2; COG0846
880633004868	Predicted membrane protein [Function unknown]; Region: COG2323
880633004869	Protein of unknown function (DUF3290); Region: DUF3290; pfam11694
880633004870	Nicotinamide mononucleotide transporter; Region: NMN_transporter; pfam04973
880633004871	choice-of-anchor A domain; Region: choice_anch_A; TIGR04215
880633004872	PAS domain; Region: PAS_10; pfam13596
880633004873	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
880633004874	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
880633004875	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
880633004876	Walker A/P-loop; other site
880633004877	ATP binding site [chemical binding]; other site
880633004878	Q-loop/lid; other site
880633004879	ABC transporter signature motif; other site
880633004880	Walker B; other site
880633004881	D-loop; other site
880633004882	H-loop/switch region; other site
880633004883	proline-specific peptidase, Bacillus coagulans-type subfamily; Region: pro_imino_pep_2; TIGR01250
880633004884	adenosine deaminase; Provisional; Region: PRK09358
880633004885	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
880633004886	active site
880633004887	Nucleoside 2-deoxyribosyltransferase; Region: Nuc_deoxyrib_tr; pfam05014
880633004888	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
880633004889	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
880633004890	elongation factor P; Validated; Region: PRK00529
880633004891	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
880633004892	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
880633004893	RNA binding site [nucleotide binding]; other site
880633004894	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
880633004895	RNA binding site [nucleotide binding]; other site
880633004896	pantothenate kinase; Provisional; Region: PRK05439
880633004897	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
880633004898	ATP-binding site [chemical binding]; other site
880633004899	CoA-binding site [chemical binding]; other site
880633004900	Mg2+-binding site [ion binding]; other site
880633004901	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
880633004902	active site
880633004903	catalytic triad [active]
880633004904	oxyanion hole [active]
880633004905	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
880633004906	Coenzyme A binding pocket [chemical binding]; other site
880633004907	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
880633004908	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
880633004909	substrate binding pocket [chemical binding]; other site
880633004910	membrane-bound complex binding site; other site
880633004911	hinge residues; other site
880633004912	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
880633004913	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
880633004914	Walker A/P-loop; other site
880633004915	ATP binding site [chemical binding]; other site
880633004916	Q-loop/lid; other site
880633004917	ABC transporter signature motif; other site
880633004918	Walker B; other site
880633004919	D-loop; other site
880633004920	H-loop/switch region; other site
880633004921	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
880633004922	dimer interface [polypeptide binding]; other site
880633004923	conserved gate region; other site
880633004924	putative PBP binding loops; other site
880633004925	ABC-ATPase subunit interface; other site
880633004926	Superfamily I DNA and RNA helicases [General function prediction only]; Region: COG3973
880633004927	Part of AAA domain; Region: AAA_19; pfam13245
880633004928	Family description; Region: UvrD_C_2; pfam13538
880633004929	Zinc-dependent metalloprotease, MMP_like subfamily. This group contains matrix metalloproteinases (MMPs), serralysins, and the astacin_like family of proteases; Region: ZnMc_MMP_like; cd04268
880633004930	active site
880633004931	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
880633004932	catalytic core [active]
880633004933	aspartate racemase; Region: asp_race; TIGR00035
880633004934	Predicted membrane protein [Function unknown]; Region: COG4640
880633004935	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
880633004936	active site
880633004937	homodimer interface [polypeptide binding]; other site
880633004938	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
880633004939	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
880633004940	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
880633004941	putative active site [active]
880633004942	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
880633004943	Glycoside Hydrolases Family 4; GlvA- and pagL-like glycosidases; Region: GH4_GlvA_pagL_like; cd05298
880633004944	NAD binding site [chemical binding]; other site
880633004945	sugar binding site [chemical binding]; other site
880633004946	divalent metal binding site [ion binding]; other site
880633004947	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
880633004948	dimer interface [polypeptide binding]; other site
880633004949	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
880633004950	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
880633004951	Coenzyme A binding pocket [chemical binding]; other site
880633004952	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
880633004953	Beta-lactamase; Region: Beta-lactamase; pfam00144
880633004954	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
880633004955	Probable transposase; Region: OrfB_IS605; pfam01385
880633004956	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
880633004957	Piccolo Zn-finger; Region: zf-piccolo; pfam05715
880633004958	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
880633004959	Beta-lactamase; Region: Beta-lactamase; cl17358
880633004960	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
880633004961	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
880633004962	active site
880633004963	tetramer interface; other site
880633004964	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
880633004965	MULE transposase domain; Region: MULE; pfam10551
880633004966	Transposase, Mutator family; Region: Transposase_mut; pfam00872
880633004967	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: HicB; COG4226
880633004968	HicB family; Region: HicB; pfam05534
880633004969	potential frameshift: common BLAST hit: gi|336054613|ref|YP_004562900.1| transposase
880633004970	potential frameshift: common BLAST hit: gi|336053839|ref|YP_004562126.1| transposase
880633004971	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
880633004972	Divergent AAA domain; Region: AAA_4; pfam04326
880633004973	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
880633004974	potential frameshift: common BLAST hit: gi|385813014|ref|YP_005849407.1| Transposase ISLhe15
880633004975	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
880633004976	RT_Bac_retron_I: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA...; Region: RT_Bac_retron_I; cd01646
880633004977	putative active site [active]
880633004978	putative NTP binding site [chemical binding]; other site
880633004979	putative nucleic acid binding site [nucleotide binding]; other site
880633004980	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
880633004981	putative substrate binding site [chemical binding]; other site
880633004982	active site
880633004983	Abi-like protein; Region: Abi_2; pfam07751
880633004984	Domain of unknown function (DUF4393); Region: DUF4393; pfam14337
880633004985	potential frameshift: common BLAST hit: gi|385813071|ref|YP_005849464.1| Transposase IS1201
880633004986	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cl00251
880633004987	Transposase, Mutator family; Region: Transposase_mut; pfam00872
880633004988	MULE transposase domain; Region: MULE; pfam10551
880633004989	Transposase, Mutator family; Region: Transposase_mut; pfam00872
880633004990	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
880633004991	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dam; COG0338
880633004992	Transposase, Mutator family; Region: Transposase_mut; pfam00872
880633004993	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
880633004994	MULE transposase domain; Region: MULE; pfam10551
880633004995	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
880633004996	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
880633004997	AAA domain; Region: AAA_21; pfam13304
880633004998	Walker A/P-loop; other site
880633004999	ATP binding site [chemical binding]; other site
880633005000	Q-loop/lid; other site
880633005001	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
880633005002	Walker B; other site
880633005003	D-loop; other site
880633005004	H-loop/switch region; other site
880633005005	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
880633005006	RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321
880633005007	NADP binding site [chemical binding]; other site
880633005008	active site
880633005009	putative substrate binding site [chemical binding]; other site
880633005010	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
880633005011	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
880633005012	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
880633005013	substrate binding site; other site
880633005014	tetramer interface; other site
880633005015	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
880633005016	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
880633005017	NAD binding site [chemical binding]; other site
880633005018	substrate binding site [chemical binding]; other site
880633005019	homodimer interface [polypeptide binding]; other site
880633005020	active site
880633005021	Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA; Region: HTH_TipAL-Mta; cd01106
880633005022	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
880633005023	DNA binding residues [nucleotide binding]
880633005024	dimer interface [polypeptide binding]; other site
880633005025	Methyltransferase domain; Region: Methyltransf_31; pfam13847
880633005026	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
880633005027	S-adenosylmethionine binding site [chemical binding]; other site
880633005028	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
880633005029	Transposase, Mutator family; Region: Transposase_mut; pfam00872
880633005030	MULE transposase domain; Region: MULE; pfam10551
880633005031	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
880633005032	Transposase; Region: DDE_Tnp_ISL3; pfam01610
880633005033	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
880633005034	Domain of unknown function (DUF4422); Region: DUF4422; pfam14393
880633005035	Helix-turn-helix domain of transposase family ISL3; Region: HTH_Tnp_ISL3; pfam13542
880633005036	Transposase; Region: DDE_Tnp_ISL3; pfam01610
880633005037	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
880633005038	putative CoA binding site [chemical binding]; other site
880633005039	putative trimer interface [polypeptide binding]; other site
880633005040	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
880633005041	Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128
880633005042	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
880633005043	trimer interface [polypeptide binding]; other site
880633005044	active site
880633005045	substrate binding site [chemical binding]; other site
880633005046	CoA binding site [chemical binding]; other site
880633005047	Glycosyltransferase sugar-binding region containing DXD motif; Region: Gly_transf_sug; pfam04488
880633005048	Mannosyltransferase OCH1 and related enzymes [Cell envelope biogenesis, outer membrane]; Region: OCH1; COG3774
880633005049	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
880633005050	active site
880633005051	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
880633005052	This family is most closely related to the GT1 family of glycosyltransferases. capH in Staphylococcus aureus has been shown to be required for the biosynthesis of the type 1 capsular polysaccharide (CP1); Region: GT1_CapH_like; cd03812
880633005053	putative ADP-binding pocket [chemical binding]; other site
880633005054	potential frameshift: common BLAST hit: gi|386337604|ref|YP_006033773.1| glycosyl transferase family protein
880633005055	Glycosyltransferase family 28 C-terminal domain; Region: Glyco_tran_28_C; pfam04101
880633005056	Oligosaccharide biosynthesis protein Alg14 like; Region: Alg14; pfam08660
880633005057	Bacterial sugar transferase; Region: Bac_transf; pfam02397
880633005058	Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: CapC; COG4464
880633005059	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
880633005060	active site
880633005061	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
880633005062	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
880633005063	Chain length determinant protein; Region: Wzz; cl15801
880633005064	Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane]; Region: COG3944
880633005065	Cell envelope-related transcriptional attenuator domain; Region: LytR_cpsA_psr; cl00581
880633005066	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
880633005067	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
880633005068	HflX GTPase family; Region: HflX; cd01878
880633005069	G1 box; other site
880633005070	GTP/Mg2+ binding site [chemical binding]; other site
880633005071	Switch I region; other site
880633005072	G2 box; other site
880633005073	G3 box; other site
880633005074	Switch II region; other site
880633005075	G4 box; other site
880633005076	G5 box; other site
880633005077	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
880633005078	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
880633005079	NlpC/P60 family; Region: NLPC_P60; pfam00877
880633005080	Uncharacterized protein family (UPF0236); Region: UPF0236; pfam06782
880633005081	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
880633005082	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
880633005083	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
880633005084	Walker A/P-loop; other site
880633005085	ATP binding site [chemical binding]; other site
880633005086	Q-loop/lid; other site
880633005087	ABC transporter signature motif; other site
880633005088	Walker B; other site
880633005089	D-loop; other site
880633005090	H-loop/switch region; other site
880633005091	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
880633005092	Walker A/P-loop; other site
880633005093	ATP binding site [chemical binding]; other site
880633005094	Q-loop/lid; other site
880633005095	ABC transporter signature motif; other site
880633005096	Walker B; other site
880633005097	D-loop; other site
880633005098	H-loop/switch region; other site
880633005099	ECF-type riboflavin transporter, S component; Region: ECF-ribofla_trS; pfam07155
880633005100	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
880633005101	This group contains class II terpene cyclases, protein prenyltransferases beta subunit, two broadly specific proteinase inhibitors alpha2-macroglobulin (alpha (2)-M) and pregnancy zone protein (PZP) and, the C3 C4 and C5 components of vertebrate...; Region: ISOPREN_C2_like; cl08267
880633005102	Uncharacterized protein family (UPF0236); Region: UPF0236; pfam06782
880633005103	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
880633005104	active site
880633005105	metal binding site [ion binding]; metal-binding site
880633005106	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
880633005107	Uncharacterized proteins with similarity to Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL_like_DUF711; cd08025
880633005108	ACT domain proteins similar to the yet uncharacterized Streptococcus pneumoniae ACT domain protein; Region: ACT_1ZPV; cd04872
880633005109	Uncharacterized protein family (UPF0236); Region: UPF0236; pfam06782
880633005110	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
880633005111	NlpC/P60 family; Region: NLPC_P60; pfam00877
880633005112	Archaea bacterial proteins of unknown function; Region: DUF234; pfam03008
880633005113	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
880633005114	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
880633005115	TFIIB zinc-binding; Region: TF_Zn_Ribbon; pfam08271
880633005116	Predicted site-specific integrase-resolvase [DNA replication, recombination, and repair]; Region: COG2452
880633005117	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cd04761
880633005118	DNA binding residues [nucleotide binding]
880633005119	Serine Recombinase (SR) family, IS607-like transposase subfamily, catalytic domain; members contain a DNA binding domain with homology to MerR/SoxR located N-terminal to the catalytic domain. Serine recombinases catalyze site-specific recombination of...; Region: SR_IS607_transposase_like; cd03769
880633005120	catalytic residues [active]
880633005121	catalytic nucleophile [active]
880633005122	potential frameshift: common BLAST hit: gi|116514445|ref|YP_813351.1| ATPase
880633005123	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
880633005124	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
880633005125	Probable transposase; Region: OrfB_IS605; pfam01385
880633005126	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
880633005127	Piccolo Zn-finger; Region: zf-piccolo; pfam05715
880633005128	Archaeal ATPase; Region: Arch_ATPase; pfam01637
880633005129	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
880633005130	NlpC/P60 family; Region: NLPC_P60; pfam00877
880633005131	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
880633005132	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
880633005133	catalytic site [active]
880633005134	G-X2-G-X-G-K; other site
880633005135	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
880633005136	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
880633005137	Probable transposase; Region: OrfB_IS605; pfam01385
880633005138	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
880633005139	Piccolo Zn-finger; Region: zf-piccolo; pfam05715
880633005140	potential frameshift: common BLAST hit: gi|161506773|ref|YP_001576723.1| transposase IS607 family
880633005141	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39A; cd02549
880633005142	putative active site [active]
880633005143	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
880633005144	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
880633005145	Piccolo Zn-finger; Region: zf-piccolo; pfam05715
880633005146	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
880633005147	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
880633005148	Probable transposase; Region: OrfB_IS605; pfam01385
880633005149	Protein of unknown function (DUF3815); Region: DUF3815; pfam12821
880633005150	Uncharacterized conserved protein [Function unknown]; Region: COG2966
880633005151	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
880633005152	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
880633005153	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
880633005154	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
880633005155	Walker A/P-loop; other site
880633005156	ATP binding site [chemical binding]; other site
880633005157	Q-loop/lid; other site
880633005158	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
880633005159	ABC transporter signature motif; other site
880633005160	Walker B; other site
880633005161	D-loop; other site
880633005162	ABC transporter; Region: ABC_tran_2; pfam12848
880633005163	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
880633005164	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
880633005165	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
880633005166	potential frameshift: common BLAST hit: gi|295693649|ref|YP_003602259.1| transport protein
880633005167	Cell envelope-related transcriptional attenuator domain; Region: LytR_cpsA_psr; cl00581
880633005168	Oligoendopeptidase F [Amino acid transport and metabolism]; Region: COG1164
880633005169	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_3; cd09608
880633005170	active site
880633005171	Zn binding site [ion binding]; other site
880633005172	potential frameshift: common BLAST hit: gi|307069365|ref|YP_003877833.1| filamentation induced by cAMP protein
880633005173	Enterocin A Immunity; Region: EntA_Immun; pfam08951
880633005174	potential frameshift: common BLAST hit: gi|58338022|ref|YP_194607.1| lactate premease
880633005175	potential frameshift: common BLAST hit: gi|295693662|ref|YP_003602272.1| L-lactate permease
880633005176	potential frameshift: common BLAST hit: gi|295693662|ref|YP_003602272.1| L-lactate permease
880633005177	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
880633005178	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
880633005179	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
880633005180	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cl00462
880633005181	dimer interface [polypeptide binding]; other site
880633005182	putative PBP binding regions; other site
880633005183	ABC-ATPase subunit  interface; other site
880633005184	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
880633005185	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
880633005186	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
880633005187	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
880633005188	intersubunit interface [polypeptide binding]; other site
880633005189	Uncharacterized protein family (UPF0236); Region: UPF0236; pfam06782
880633005190	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
880633005191	dimerization interface [polypeptide binding]; other site
880633005192	putative DNA binding site [nucleotide binding]; other site
880633005193	putative Zn2+ binding site [ion binding]; other site
880633005194	potential frameshift: common BLAST hit: gi|161507783|ref|YP_001577747.1| transposase
880633005195	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
880633005196	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
880633005197	active site
880633005198	phosphorylation site [posttranslational modification]
880633005199	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
880633005200	active site
880633005201	P-loop; other site
880633005202	phosphorylation site [posttranslational modification]
880633005203	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
880633005204	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
880633005205	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
880633005206	putative substrate binding site [chemical binding]; other site
880633005207	putative ATP binding site [chemical binding]; other site
880633005208	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
880633005209	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
880633005210	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
880633005211	RelB antitoxin; Region: RelB; cl01171
880633005212	potential frameshift: common BLAST hit: gi|385813883|ref|YP_005850276.1| transposase
880633005213	putative alpha-glucosidase; Provisional; Region: PRK10658
880633005214	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
880633005215	Alpha-glucosidase II (alpha-D-glucoside glucohydrolase) is a glycosyl hydrolase family 31 (GH31) enzyme, found in bacteria and plants, which has exo-alpha-1,4-glucosidase and oligo-1,6-glucosidase activities. Alpha-glucosidase II has been characterized...; Region: GH31_glucosidase_II_MalA; cd06604
880633005216	trimer interface [polypeptide binding]; other site
880633005217	active site
880633005218	homohexamer (dimer of homotrimer) interface [polypeptide binding]; other site
880633005219	catalytic site [active]
880633005220	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
880633005221	salt bridge; other site
880633005222	non-specific DNA binding site [nucleotide binding]; other site
880633005223	sequence-specific DNA binding site [nucleotide binding]; other site
880633005224	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
880633005225	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
880633005226	Probable transposase; Region: OrfB_IS605; pfam01385
880633005227	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
880633005228	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
880633005229	Piccolo Zn-finger; Region: zf-piccolo; pfam05715
880633005230	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
880633005231	aspartate racemase; Region: asp_race; TIGR00035
880633005232	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
880633005233	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
880633005234	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
880633005235	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
880633005236	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
880633005237	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
880633005238	dimer interface [polypeptide binding]; other site
880633005239	phosphorylation site [posttranslational modification]
880633005240	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
880633005241	ATP binding site [chemical binding]; other site
880633005242	Mg2+ binding site [ion binding]; other site
880633005243	G-X-G motif; other site
880633005244	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
880633005245	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
880633005246	active site
880633005247	phosphorylation site [posttranslational modification]
880633005248	intermolecular recognition site; other site
880633005249	dimerization interface [polypeptide binding]; other site
880633005250	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
880633005251	DNA binding site [nucleotide binding]
880633005252	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
880633005253	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
880633005254	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
880633005255	Walker A/P-loop; other site
880633005256	ATP binding site [chemical binding]; other site
880633005257	Q-loop/lid; other site
880633005258	ABC transporter signature motif; other site
880633005259	Walker B; other site
880633005260	D-loop; other site
880633005261	H-loop/switch region; other site
880633005262	potential frameshift: common BLAST hit: gi|385814601|ref|YP_005850994.1| ABC-transporter, ATPase and permease components
880633005263	Protein of unknown function (DUF1129); Region: DUF1129; pfam06570
880633005264	GTP-binding protein YchF; Reviewed; Region: PRK09601
880633005265	YchF GTPase; Region: YchF; cd01900
880633005266	G1 box; other site
880633005267	GTP/Mg2+ binding site [chemical binding]; other site
880633005268	Switch I region; other site
880633005269	G2 box; other site
880633005270	Switch II region; other site
880633005271	G3 box; other site
880633005272	G4 box; other site
880633005273	G5 box; other site
880633005274	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
880633005275	Bacterial protein of unknown function (DUF951); Region: DUF951; pfam06107
880633005276	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
880633005277	ParB-like nuclease domain; Region: ParB; smart00470
880633005278	Helix-turn-helix; Region: HTH_3; pfam01381
880633005279	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
880633005280	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
880633005281	P-loop; other site
880633005282	Magnesium ion binding site [ion binding]; other site
880633005283	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
880633005284	Magnesium ion binding site [ion binding]; other site
880633005285	nucleoid occlusion protein; Region: nucleoid_noc; TIGR04285
880633005286	ParB-like nuclease domain; Region: ParB; smart00470
880633005287	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
880633005288	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
880633005289	S-adenosylmethionine binding site [chemical binding]; other site
880633005290	Colicin V production protein; Region: Colicin_V; pfam02674
880633005291	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
880633005292	ApbE family; Region: ApbE; pfam02424
880633005293	Tyrosine phosphatase family; Region: Y_phosphatase3; pfam13350
880633005294	Tyrosine phosphatase family C-terminal region; Region: Y_phosphatase3C; pfam13348
880633005295	Predicted flavoprotein [General function prediction only]; Region: COG0431
880633005296	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
880633005297	Predicted flavoprotein [General function prediction only]; Region: COG0431
880633005298	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
880633005299	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
880633005300	WHG domain; Region: WHG; pfam13305
880633005301	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
880633005302	MULE transposase domain; Region: MULE; pfam10551
880633005303	Transposase, Mutator family; Region: Transposase_mut; pfam00872
880633005304	Peptidase family C69; Region: Peptidase_C69; pfam03577
880633005305	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
880633005306	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
880633005307	Walker A/P-loop; other site
880633005308	ATP binding site [chemical binding]; other site
880633005309	Q-loop/lid; other site
880633005310	ABC transporter signature motif; other site
880633005311	Walker B; other site
880633005312	D-loop; other site
880633005313	H-loop/switch region; other site
880633005314	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
880633005315	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
880633005316	FtsX-like permease family; Region: FtsX; pfam02687
880633005317	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
880633005318	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
880633005319	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
880633005320	catalytic core [active]
880633005321	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
880633005322	hypothetical protein; Validated; Region: PRK02101
880633005323	Probable transposase; Region: OrfB_IS605; pfam01385
880633005324	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
880633005325	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
880633005326	Piccolo Zn-finger; Region: zf-piccolo; pfam05715
880633005327	Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229
880633005328	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
880633005329	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
880633005330	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
880633005331	putative substrate translocation pore; other site
880633005332	POT family; Region: PTR2; cl17359
880633005333	Peptidase family M1; Region: Peptidase_M1; pfam01433
880633005334	Peptidase M1 Aminopeptidase N family incudes tricorn interacting factor F3, Endoplasmic reticulum aminopeptidase 1 (ERAP1), Aminopeptidase Q (APQ); Region: M1_APN_2; cd09601
880633005335	Zn binding site [ion binding]; other site
880633005336	Domain of unknown function (DUF3358); Region: DUF3358; pfam11838
880633005337	drug efflux system protein MdtG; Provisional; Region: PRK09874
880633005338	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
880633005339	putative substrate translocation pore; other site
880633005340	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
880633005341	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
880633005342	non-specific DNA binding site [nucleotide binding]; other site
880633005343	salt bridge; other site
880633005344	sequence-specific DNA binding site [nucleotide binding]; other site
880633005345	H+ Antiporter protein; Region: 2A0121; TIGR00900
880633005346	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
880633005347	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
880633005348	non-specific DNA binding site [nucleotide binding]; other site
880633005349	salt bridge; other site
880633005350	sequence-specific DNA binding site [nucleotide binding]; other site
880633005351	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
880633005352	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
880633005353	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
880633005354	Piccolo Zn-finger; Region: zf-piccolo; pfam05715
880633005355	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
880633005356	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
880633005357	Probable transposase; Region: OrfB_IS605; pfam01385
880633005358	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
880633005359	Transposase, Mutator family; Region: Transposase_mut; pfam00872
880633005360	potential frameshift: common BLAST hit: gi|315039225|ref|YP_004032793.1| transposase
880633005361	Enterocin A Immunity; Region: EntA_Immun; pfam08951
880633005362	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK07187
880633005363	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
880633005364	Class I ribonucleotide reductase; Region: RNR_I; cd01679
880633005365	active site
880633005366	dimer interface [polypeptide binding]; other site
880633005367	catalytic residues [active]
880633005368	effector binding site; other site
880633005369	R2 peptide binding site; other site
880633005370	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
880633005371	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
880633005372	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
880633005373	dimer interface [polypeptide binding]; other site
880633005374	putative radical transfer pathway; other site
880633005375	diiron center [ion binding]; other site
880633005376	tyrosyl radical; other site
880633005377	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
880633005378	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
880633005379	NAD(P) binding site [chemical binding]; other site
880633005380	active site
880633005381	NLPA lipoprotein; Region: Lipoprotein_9; cl17547
880633005382	potential frameshift: common BLAST hit: gi|385813273|ref|YP_005849666.1| Transposase ISLhe15
880633005383	potential frameshift: common BLAST hit: gi|385813273|ref|YP_005849666.1| Transposase ISLhe15
880633005384	S-ribosylhomocysteinase; Provisional; Region: PRK02260
880633005385	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
880633005386	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
880633005387	THF binding site; other site
880633005388	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
880633005389	substrate binding site [chemical binding]; other site
880633005390	THF binding site; other site
880633005391	zinc-binding site [ion binding]; other site
880633005392	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
880633005393	FAD binding site [chemical binding]; other site
880633005394	Probable transposase; Region: OrfB_IS605; pfam01385
880633005395	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
880633005396	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
880633005397	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
880633005398	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
880633005399	Helix-turn-helix domain; Region: HTH_38; pfam13936
880633005400	Integrase core domain; Region: rve; pfam00665
880633005401	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
880633005402	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
880633005403	active site
880633005404	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
880633005405	Transposase; Region: DDE_Tnp_ISL3; pfam01610
880633005406	BioY family; Region: BioY; pfam02632
880633005407	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
880633005408	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
880633005409	putative DNA binding site [nucleotide binding]; other site
880633005410	putative Zn2+ binding site [ion binding]; other site
880633005411	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
880633005412	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
880633005413	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK06079
880633005414	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
880633005415	NAD binding site [chemical binding]; other site
880633005416	homotetramer interface [polypeptide binding]; other site
880633005417	homodimer interface [polypeptide binding]; other site
880633005418	substrate binding site [chemical binding]; other site
880633005419	active site
880633005420	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
880633005421	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
880633005422	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
880633005423	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
880633005424	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
880633005425	ATP-grasp domain; Region: ATP-grasp_4; cl17255
880633005426	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
880633005427	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
880633005428	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
880633005429	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
880633005430	carboxyltransferase (CT) interaction site; other site
880633005431	biotinylation site [posttranslational modification]; other site
880633005432	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
880633005433	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
880633005434	dimer interface [polypeptide binding]; other site
880633005435	active site
880633005436	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
880633005437	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
880633005438	NAD(P) binding site [chemical binding]; other site
880633005439	active site
880633005440	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
880633005441	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
880633005442	acyl carrier protein; Provisional; Region: acpP; PRK00982
880633005443	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
880633005444	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
880633005445	dimer interface [polypeptide binding]; other site
880633005446	active site
880633005447	CoA binding pocket [chemical binding]; other site
880633005448	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
880633005449	MarR family; Region: MarR_2; pfam12802
880633005450	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
880633005451	potential frameshift: common BLAST hit: gi|336055271|ref|YP_004563558.1| pyrimidine-nucleoside phosphorylase
880633005452	potential frameshift: common BLAST hit: gi|385814683|ref|YP_005851076.1| Sugar transporter superfamily protein YceI
880633005453	nicotinate-nucleotide pyrophosphorylase; Provisional; Region: PRK08072
880633005454	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
880633005455	dimerization interface [polypeptide binding]; other site
880633005456	active site
880633005457	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
880633005458	Transposase; Region: DDE_Tnp_ISL3; pfam01610
880633005459	Helix-turn-helix domain of transposase family ISL3; Region: HTH_Tnp_ISL3; pfam13542
880633005460	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
880633005461	Walker A/P-loop; other site
880633005462	ATP binding site [chemical binding]; other site
880633005463	Q-loop/lid; other site
880633005464	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
880633005465	ABC transporter signature motif; other site
880633005466	Walker B; other site
880633005467	D-loop; other site
880633005468	H-loop/switch region; other site
880633005469	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
880633005470	AAA domain; Region: AAA_21; pfam13304
880633005471	Walker A/P-loop; other site
880633005472	ATP binding site [chemical binding]; other site
880633005473	Q-loop/lid; other site
880633005474	ABC transporter signature motif; other site
880633005475	Walker B; other site
880633005476	D-loop; other site
880633005477	H-loop/switch region; other site
880633005478	Integrase core domain; Region: rve; pfam00665
880633005479	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
880633005480	Helix-turn-helix domain; Region: HTH_28; pfam13518
880633005481	Helix-turn-helix domain; Region: HTH_28; pfam13518
880633005482	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
880633005483	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
880633005484	pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK07251
880633005485	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
880633005486	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
880633005487	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
880633005488	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
880633005489	Transposase; Region: DDE_Tnp_ISL3; pfam01610
880633005490	nicotinate-nucleotide pyrophosphorylase; Provisional; Region: PRK08072
880633005491	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
880633005492	dimerization interface [polypeptide binding]; other site
880633005493	active site
880633005494	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
880633005495	putative substrate translocation pore; other site
880633005496	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
880633005497	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cl17393
880633005498	Integrase core domain; Region: rve_2; pfam13333
880633005499	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
880633005500	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
880633005501	putative substrate translocation pore; other site
880633005502	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
880633005503	Integrase core domain; Region: rve; pfam00665
880633005504	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
880633005505	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
880633005506	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
880633005507	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
880633005508	active site
880633005509	ribulose/triose binding site [chemical binding]; other site
880633005510	phosphate binding site [ion binding]; other site
880633005511	substrate (anthranilate) binding pocket [chemical binding]; other site
880633005512	product (indole) binding pocket [chemical binding]; other site
880633005513	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
880633005514	active site
880633005515	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
880633005516	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
880633005517	pyridoxal 5'-phosphate binding site [chemical binding]; other site
880633005518	catalytic residue [active]
880633005519	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
880633005520	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
880633005521	substrate binding site [chemical binding]; other site
880633005522	active site
880633005523	catalytic residues [active]
880633005524	heterodimer interface [polypeptide binding]; other site
880633005525	Transposase [DNA replication, recombination, and repair]; Region: COG5421
880633005526	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
880633005527	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
880633005528	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
880633005529	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
880633005530	dimer interface [polypeptide binding]; other site
880633005531	pyridoxal 5'-phosphate binding site [chemical binding]; other site
880633005532	catalytic residue [active]
880633005533	cystathionine beta-lyase; Provisional; Region: PRK07671
880633005534	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
880633005535	homodimer interface [polypeptide binding]; other site
880633005536	substrate-cofactor binding pocket; other site
880633005537	pyridoxal 5'-phosphate binding site [chemical binding]; other site
880633005538	catalytic residue [active]
880633005539	serine O-acetyltransferase; Region: cysE; TIGR01172
880633005540	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
880633005541	trimer interface [polypeptide binding]; other site
880633005542	active site
880633005543	substrate binding site [chemical binding]; other site
880633005544	CoA binding site [chemical binding]; other site
880633005545	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
880633005546	Transposase; Region: DEDD_Tnp_IS110; pfam01548
880633005547	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
880633005548	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4223
880633005549	choice-of-anchor A domain; Region: choice_anch_A; TIGR04215
880633005550	MucBP domain; Region: MucBP; pfam06458
880633005551	MucBP domain; Region: MucBP; pfam06458
880633005552	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
880633005553	KxYKxGKxW signal peptide; Region: KxYKxGKxW; TIGR03715
880633005554	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
880633005555	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
880633005556	catalytic residues [active]
880633005557	catalytic nucleophile [active]
880633005558	Macro domain, a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Some macro domains recognize poly...; Region: Macro; cl00019
880633005559	ADP-ribose binding site [chemical binding]; other site
880633005560	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
880633005561	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
880633005562	dimer interface [polypeptide binding]; other site
880633005563	conserved gate region; other site
880633005564	putative PBP binding loops; other site
880633005565	ABC-ATPase subunit interface; other site
880633005566	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
880633005567	dimer interface [polypeptide binding]; other site
880633005568	conserved gate region; other site
880633005569	ABC-ATPase subunit interface; other site
880633005570	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
880633005571	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
880633005572	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
880633005573	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
880633005574	Walker A/P-loop; other site
880633005575	ATP binding site [chemical binding]; other site
880633005576	Q-loop/lid; other site
880633005577	ABC transporter signature motif; other site
880633005578	Walker B; other site
880633005579	D-loop; other site
880633005580	H-loop/switch region; other site
880633005581	TOBE domain; Region: TOBE_2; pfam08402
880633005582	beta-phosphoglucomutase; Region: bPGM; TIGR01990
880633005583	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
880633005584	motif II; other site
880633005585	maltose phosphorylase; Provisional; Region: PRK13807
880633005586	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
880633005587	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
880633005588	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
880633005589	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
880633005590	homodimer interface [polypeptide binding]; other site
880633005591	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
880633005592	active site
880633005593	homodimer interface [polypeptide binding]; other site
880633005594	catalytic site [active]
880633005595	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
880633005596	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
880633005597	Ca binding site [ion binding]; other site
880633005598	active site
880633005599	catalytic site [active]
880633005600	Acetokinase family; Region: Acetate_kinase; cl17229
880633005601	potential frameshift: common BLAST hit: gi|385814532|ref|YP_005850925.1| Transposase IS607 family
880633005602	Acetokinase family; Region: Acetate_kinase; cl17229
880633005603	Transcriptional regulators [Transcription]; Region: PurR; COG1609
880633005604	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
880633005605	DNA binding site [nucleotide binding]
880633005606	domain linker motif; other site
880633005607	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
880633005608	ligand binding site [chemical binding]; other site
880633005609	dimerization interface [polypeptide binding]; other site
880633005610	Tyrosine phosphatase family; Region: Y_phosphatase3; pfam13350
880633005611	Tyrosine phosphatase family C-terminal region; Region: Y_phosphatase3C; pfam13348
880633005612	glycerol kinase; Provisional; Region: glpK; PRK00047
880633005613	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
880633005614	N- and C-terminal domain interface [polypeptide binding]; other site
880633005615	active site
880633005616	MgATP binding site [chemical binding]; other site
880633005617	catalytic site [active]
880633005618	metal binding site [ion binding]; metal-binding site
880633005619	glycerol binding site [chemical binding]; other site
880633005620	homotetramer interface [polypeptide binding]; other site
880633005621	homodimer interface [polypeptide binding]; other site
880633005622	FBP binding site [chemical binding]; other site
880633005623	protein IIAGlc interface [polypeptide binding]; other site
880633005624	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
880633005625	dimer interface [polypeptide binding]; other site
880633005626	substrate binding site [chemical binding]; other site
880633005627	ATP binding site [chemical binding]; other site
880633005628	RelB antitoxin; Region: RelB; cl01171
880633005629	Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016
880633005630	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
880633005631	catalytic triad [active]
880633005632	Integrase core domain; Region: rve_2; pfam13333
880633005633	Uncharacterized protein family (UPF0236); Region: UPF0236; pfam06782
880633005634	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
880633005635	Helix-turn-helix domain; Region: HTH_28; pfam13518
880633005636	HTH-like domain; Region: HTH_21; pfam13276
880633005637	Integrase core domain; Region: rve; pfam00665
880633005638	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
880633005639	NlpC/P60 family; Region: NLPC_P60; pfam00877
880633005640	EamA-like transporter family; Region: EamA; pfam00892
880633005641	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
880633005642	EamA-like transporter family; Region: EamA; pfam00892
880633005643	potential frameshift: common BLAST hit: gi|385814710|ref|YP_005851103.1| Membrane protein
880633005644	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
880633005645	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
880633005646	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
880633005647	Walker A/P-loop; other site
880633005648	ATP binding site [chemical binding]; other site
880633005649	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
880633005650	Adenylosuccinate lyase [Nucleotide transport and metabolism]; Region: PurB; COG0015
880633005651	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
880633005652	tetramer interface [polypeptide binding]; other site
880633005653	active site
880633005654	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
880633005655	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
880633005656	GDP-binding site [chemical binding]; other site
880633005657	ACT binding site; other site
880633005658	IMP binding site; other site
880633005659	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05458
880633005660	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
880633005661	active site
880633005662	Uncharacterized conserved protein [Function unknown]; Region: COG3589
880633005663	Bacterial protein of unknown function (DUF871); Region: DUF871; pfam05913
880633005664	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
880633005665	dimer interface [polypeptide binding]; other site
880633005666	active site
880633005667	Helix-turn-helix domain; Region: HTH_38; pfam13936
880633005668	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
880633005669	Integrase core domain; Region: rve; pfam00665
880633005670	potential frameshift: common BLAST hit: gi|385812926|ref|YP_005849319.1| Transposase, IS30 family
880633005671	thiazole/oxazole-forming peptide maturase, SagD family component; Region: TOMM_cyclo_SagD; TIGR03604
880633005672	YcaO-like family; Region: YcaO; pfam02624
880633005673	This family is the oxydase domain of NRPS (non-ribosomal peptide synthetase) and other proteins that modify polypeptides by cyclizing a thioester to form a ring. These include epoB, part of the epothilone biosynthesis pathway; tubD, part of the tubulysin...; Region: mcbC-like_oxidoreductase; cd02142
880633005674	putative FMN binding site [chemical binding]; other site
880633005675	NADPH bind site [chemical binding]; other site
880633005676	potential frameshift: common BLAST hit: gi|336054615|ref|YP_004562902.1| transposase
880633005677	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
880633005678	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
880633005679	Walker A/P-loop; other site
880633005680	ATP binding site [chemical binding]; other site
880633005681	Q-loop/lid; other site
880633005682	ABC transporter signature motif; other site
880633005683	Walker B; other site
880633005684	D-loop; other site
880633005685	H-loop/switch region; other site
880633005686	Transposase, Mutator family; Region: Transposase_mut; pfam00872
880633005687	MULE transposase domain; Region: MULE; pfam10551
880633005688	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
880633005689	Peptidase C26; Region: Peptidase_C26; pfam07722
880633005690	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
880633005691	catalytic triad [active]
880633005692	putative transport protein YifK; Provisional; Region: PRK10746
880633005693	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
880633005694	cAMP-dependent protein kinase catalytic subunit; Provisional; Region: PTZ00426
880633005695	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
880633005696	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
880633005697	Catalytic site [active]
880633005698	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
880633005699	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
880633005700	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
880633005701	Walker A motif; other site
880633005702	ATP binding site [chemical binding]; other site
880633005703	Walker B motif; other site
880633005704	arginine finger; other site
880633005705	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
880633005706	Walker A motif; other site
880633005707	ATP binding site [chemical binding]; other site
880633005708	Walker B motif; other site
880633005709	arginine finger; other site
880633005710	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
880633005711	Alpha/beta hydrolase of unknown function (DUF915); Region: DUF915; pfam06028
880633005712	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; cl17295
880633005713	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
880633005714	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
880633005715	Walker A/P-loop; other site
880633005716	ATP binding site [chemical binding]; other site
880633005717	Q-loop/lid; other site
880633005718	ABC transporter signature motif; other site
880633005719	Walker B; other site
880633005720	D-loop; other site
880633005721	H-loop/switch region; other site
880633005722	potential frameshift: common BLAST hit: gi|295693820|ref|YP_003602430.1| ABC transporter, permease protein
880633005723	potential frameshift: common BLAST hit: gi|385818397|ref|YP_005854787.1| ABC transporter permease
880633005724	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
880633005725	Cpl-1 lysin (also known as Cpl-9 lysozyme / muramidase) is a bacterial cell wall endolysin encoded by the pneumococcal bacteriophage Cp-1, which cleaves the glycosidic N-acetylmuramoyl-(beta1,4)-N-acetylglucosamine bonds of the pneumococcal glycan chain; Region: GH25_Cpl1-like; cd06415
880633005726	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
880633005727	active site
880633005728	Protein of unknown function (DUF975); Region: DUF975; cl10504
880633005729	CAAX protease self-immunity; Region: Abi; pfam02517
880633005730	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
880633005731	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
880633005732	non-specific DNA binding site [nucleotide binding]; other site
880633005733	salt bridge; other site
880633005734	sequence-specific DNA binding site [nucleotide binding]; other site
880633005735	Beta-lactamase; Region: Beta-lactamase; pfam00144
880633005736	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
880633005737	D-alanyl-lipoteichoic acid biosynthesis protein DltD; Region: LTA_DltD; TIGR04092
880633005738	DltD N-terminal region; Region: DltD_N; pfam04915
880633005739	DltD central region; Region: DltD_M; pfam04918
880633005740	DltD C-terminal region; Region: DltD_C; pfam04914
880633005741	D-alanine--poly(phosphoribitol) ligase subunit 2; Validated; Region: PRK05087
880633005742	D-alanyl-lipoteichoic acid biosynthesis protein DltB; Region: LTA_dltB; TIGR04091
880633005743	D-alanine--poly(phosphoribitol) ligase subunit 1; Provisional; Region: PRK04813
880633005744	D-alanine:D-alanyl carrier protein ligase (DltA); Region: DltA; cd05945
880633005745	acyl-activating enzyme (AAE) consensus motif; other site
880633005746	AMP binding site [chemical binding]; other site
880633005747	D-Ala-teichoic acid biosynthesis protein; Region: DUF3687; pfam12459
880633005748	PQQ-like domain; Region: PQQ_2; pfam13360
880633005749	FOG: CBS domain [General function prediction only]; Region: COG0517
880633005750	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_30; cd04643
880633005751	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
880633005752	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
880633005753	Soluble P-type ATPase [General function prediction only]; Region: COG4087
880633005754	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
880633005755	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
880633005756	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
880633005757	Plasmid encoded toxin Txe; Region: Plasmid_Txe; cl17389
880633005758	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
880633005759	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
880633005760	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
880633005761	Walker A/P-loop; other site
880633005762	ATP binding site [chemical binding]; other site
880633005763	Q-loop/lid; other site
880633005764	ABC transporter signature motif; other site
880633005765	Walker B; other site
880633005766	D-loop; other site
880633005767	H-loop/switch region; other site
880633005768	Domain of unknown function (DUF4097); Region: DUF4097; pfam13349
880633005769	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
880633005770	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
880633005771	non-specific DNA binding site [nucleotide binding]; other site
880633005772	salt bridge; other site
880633005773	sequence-specific DNA binding site [nucleotide binding]; other site
880633005774	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
880633005775	Helix-turn-helix domain of transposase family ISL3; Region: HTH_Tnp_ISL3; pfam13542
880633005776	Transposase; Region: DDE_Tnp_ISL3; pfam01610
880633005777	potential frameshift: common BLAST hit: gi|385814482|ref|YP_005850875.1| transposase
880633005778	Toxin Fst, type I toxin-antitoxin system; Region: Fst_toxin; pfam13955
880633005779	CAAX protease self-immunity; Region: Abi; pfam02517
880633005780	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
880633005781	putative active site [active]
880633005782	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
880633005783	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
880633005784	Walker A/P-loop; other site
880633005785	ATP binding site [chemical binding]; other site
880633005786	Q-loop/lid; other site
880633005787	ABC transporter signature motif; other site
880633005788	Walker B; other site
880633005789	D-loop; other site
880633005790	H-loop/switch region; other site
880633005791	FtsX-like permease family; Region: FtsX; pfam02687
880633005792	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
880633005793	Predicted membrane protein [Function unknown]; Region: COG4684
880633005794	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
880633005795	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
880633005796	active site
880633005797	catalytic tetrad [active]
880633005798	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
880633005799	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
880633005800	active site
880633005801	trimer interface [polypeptide binding]; other site
880633005802	allosteric site; other site
880633005803	active site lid [active]
880633005804	hexamer (dimer of trimers) interface [polypeptide binding]; other site
880633005805	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
880633005806	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
880633005807	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
880633005808	putative active site [active]
880633005809	Uncharacterized conserved protein [Function unknown]; Region: COG3589
880633005810	Bacterial protein of unknown function (DUF871); Region: DUF871; pfam05913
880633005811	Beta-lactamase; Region: Beta-lactamase; cl17358
880633005812	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
880633005813	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
880633005814	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
880633005815	putative active site [active]
880633005816	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
880633005817	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
880633005818	active site turn [active]
880633005819	phosphorylation site [posttranslational modification]
880633005820	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
880633005821	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
880633005822	HPr interaction site; other site
880633005823	glycerol kinase (GK) interaction site [polypeptide binding]; other site
880633005824	active site
880633005825	phosphorylation site [posttranslational modification]
880633005826	potential frameshift: common BLAST hit: gi|336054615|ref|YP_004562902.1| transposase
880633005827	Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428
880633005828	Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1; Region: dNK; cd01673
880633005829	Substrate-binding site [chemical binding]; other site
880633005830	Substrate specificity [chemical binding]; other site
880633005831	Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428
880633005832	Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1; Region: dNK; cd01673
880633005833	Substrate-binding site [chemical binding]; other site
880633005834	Substrate specificity [chemical binding]; other site
880633005835	potential frameshift: common BLAST hit: gi|385813500|ref|YP_005849893.1| transposase
880633005836	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
880633005837	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
880633005838	active site
880633005839	motif I; other site
880633005840	motif II; other site
880633005841	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
880633005842	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
880633005843	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
880633005844	AAA domain; Region: AAA_14; pfam13173
880633005845	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
880633005846	Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA; Region: HTH_TipAL-Mta; cd01106
880633005847	DNA binding residues [nucleotide binding]
880633005848	dimer interface [polypeptide binding]; other site
880633005849	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
880633005850	potential frameshift: common BLAST hit: gi|385813273|ref|YP_005849666.1| Transposase ISLhe15
880633005851	Ammonia permease [Inorganic ion transport and metabolism]; Region: AmtB; COG0004
880633005852	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
880633005853	copper transport repressor, CopY/TcrY family; Region: CopY_TcrY; TIGR02698
880633005854	Penicillinase repressor; Region: Pencillinase_R; pfam03965
880633005855	Cupredoxin-like domain; Region: Cupredoxin_1; pfam13473
880633005856	Cupredoxin-like domain; Region: Cupredoxin_1; pfam13473
880633005857	copper-(or silver)-translocating P-type ATPase; Region: ATPase-IB1_Cu; TIGR01511
880633005858	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
880633005859	Soluble P-type ATPase [General function prediction only]; Region: COG4087
880633005860	potential frameshift: common BLAST hit: gi|295693875|ref|YP_003602485.1| major facilitator superfamily permease
880633005861	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
880633005862	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
880633005863	Cl- selectivity filter; other site
880633005864	Cl- binding residues [ion binding]; other site
880633005865	pore gating glutamate residue; other site
880633005866	dimer interface [polypeptide binding]; other site
880633005867	H+/Cl- coupling transport residue; other site
880633005868	TrkA-C domain; Region: TrkA_C; pfam02080
880633005869	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
880633005870	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
880633005871	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
880633005872	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
880633005873	pyruvate oxidase; Region: pyruv_oxi_spxB; TIGR02720
880633005874	PYR/PP interface [polypeptide binding]; other site
880633005875	dimer interface [polypeptide binding]; other site
880633005876	tetramer interface [polypeptide binding]; other site
880633005877	TPP binding site [chemical binding]; other site
880633005878	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
880633005879	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
880633005880	TPP-binding site [chemical binding]; other site
880633005881	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
880633005882	tRNA:m(5)U-54 methyltransferase; Region: gid_trmFO; TIGR00137
880633005883	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
880633005884	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
880633005885	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
880633005886	trmE is a tRNA modification GTPase; Region: trmE; cd04164
880633005887	G1 box; other site
880633005888	GTP/Mg2+ binding site [chemical binding]; other site
880633005889	Switch I region; other site
880633005890	G2 box; other site
880633005891	Switch II region; other site
880633005892	G3 box; other site
880633005893	G4 box; other site
880633005894	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
880633005895	Preprotein translocase subunit YidC [Intracellular trafficking and secretion]; Region: YidC; COG0706
880633005896	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
880633005897	ribonuclease P; Reviewed; Region: rnpA; PRK00499
880633005898	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399