-- dump date   	20140619_124558
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1088720000001	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
1088720000002	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1088720000003	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1088720000004	Walker A motif; other site
1088720000005	ATP binding site [chemical binding]; other site
1088720000006	Walker B motif; other site
1088720000007	arginine finger; other site
1088720000008	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1088720000009	DnaA box-binding interface [nucleotide binding]; other site
1088720000010	DNA polymerase III subunit beta; Validated; Region: PRK05643
1088720000011	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1088720000012	putative DNA binding surface [nucleotide binding]; other site
1088720000013	dimer interface [polypeptide binding]; other site
1088720000014	beta-clamp/clamp loader binding surface; other site
1088720000015	beta-clamp/translesion DNA polymerase binding surface; other site
1088720000016	S4-like RNA binding protein [Replication, recombination, and repair]; Region: COG2501
1088720000017	recombination protein F; Reviewed; Region: recF; PRK00064
1088720000018	ATP-binding cassette domain of RecF; Region: ABC_RecF; cd03242
1088720000019	Walker A/P-loop; other site
1088720000020	ATP binding site [chemical binding]; other site
1088720000021	Q-loop/lid; other site
1088720000022	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720000023	ABC transporter signature motif; other site
1088720000024	Walker B; other site
1088720000025	D-loop; other site
1088720000026	H-loop/switch region; other site
1088720000027	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
1088720000028	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1088720000029	Mg2+ binding site [ion binding]; other site
1088720000030	G-X-G motif; other site
1088720000031	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1088720000032	anchoring element; other site
1088720000033	dimer interface [polypeptide binding]; other site
1088720000034	ATP binding site [chemical binding]; other site
1088720000035	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1088720000036	active site
1088720000037	metal binding site [ion binding]; metal-binding site
1088720000038	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1088720000039	DNA gyrase subunit A; Validated; Region: PRK05560
1088720000040	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1088720000041	CAP-like domain; other site
1088720000042	active site
1088720000043	primary dimer interface [polypeptide binding]; other site
1088720000044	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1088720000045	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1088720000046	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1088720000047	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1088720000048	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1088720000049	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1088720000050	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
1088720000051	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1088720000052	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1088720000053	dimer interface [polypeptide binding]; other site
1088720000054	ssDNA binding site [nucleotide binding]; other site
1088720000055	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1088720000056	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1088720000057	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1088720000058	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1088720000059	dimer interface [polypeptide binding]; other site
1088720000060	ssDNA binding site [nucleotide binding]; other site
1088720000061	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1088720000062	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1088720000063	intracellular protease, PfpI family; Region: PfpI; TIGR01382
1088720000064	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
1088720000065	proposed catalytic triad [active]
1088720000066	conserved cys residue [active]
1088720000067	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
1088720000068	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1088720000069	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
1088720000070	CAAX protease self-immunity; Region: Abi; pfam02517
1088720000071	ABC-2 type transporter; Region: ABC2_membrane; cl17235
1088720000072	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1088720000073	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1088720000074	Walker A/P-loop; other site
1088720000075	ATP binding site [chemical binding]; other site
1088720000076	Q-loop/lid; other site
1088720000077	ABC transporter signature motif; other site
1088720000078	Walker B; other site
1088720000079	D-loop; other site
1088720000080	H-loop/switch region; other site
1088720000081	Ammonium Transporter Family; Region: Ammonium_transp; cl03012
1088720000082	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_3; pfam13738
1088720000083	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883
1088720000084	CHAP domain; Region: CHAP; pfam05257
1088720000085	Surface antigen [General function prediction only]; Region: COG3942
1088720000086	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1088720000087	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1088720000088	FtsX-like permease family; Region: FtsX; pfam02687
1088720000089	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1088720000090	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1088720000091	Walker A/P-loop; other site
1088720000092	ATP binding site [chemical binding]; other site
1088720000093	Q-loop/lid; other site
1088720000094	ABC transporter signature motif; other site
1088720000095	Walker B; other site
1088720000096	D-loop; other site
1088720000097	H-loop/switch region; other site
1088720000098	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1088720000099	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1088720000100	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
1088720000101	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1088720000102	active site
1088720000103	motif I; other site
1088720000104	motif II; other site
1088720000105	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1088720000106	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1088720000107	Protein of unknown function (DUF1211); Region: DUF1211; cl01421
1088720000108	galactoside O-acetyltransferase; Reviewed; Region: lacA; PRK09527
1088720000109	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
1088720000110	active site
1088720000111	substrate binding site [chemical binding]; other site
1088720000112	trimer interface [polypeptide binding]; other site
1088720000113	CoA binding site [chemical binding]; other site
1088720000114	Peptidase family C69; Region: Peptidase_C69; pfam03577
1088720000115	Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane]; Region: COG3409
1088720000116	BacA is a bacterial lysin from Enterococcus faecalis that degrades bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues. BacA is homologous to the YbfG and YkuG lysins of...; Region: GH25_BacA-like; cd06418
1088720000117	active site
1088720000118	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
1088720000119	Predicted membrane protein [Function unknown]; Region: COG4392
1088720000120	beta-D-glucuronidase; Provisional; Region: PRK10150
1088720000121	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1088720000122	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1088720000123	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1088720000124	Glycosyl hydrolase family 59; Region: Glyco_hydro_59; pfam02057
1088720000125	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
1088720000126	2-keto-3-deoxy-6-phosphogluconate aldolase [Carbohydrate transport and metabolism]; Region: Eda; COG0800
1088720000127	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1088720000128	active site
1088720000129	intersubunit interface [polypeptide binding]; other site
1088720000130	catalytic residue [active]
1088720000131	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1088720000132	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1088720000133	substrate binding site [chemical binding]; other site
1088720000134	ATP binding site [chemical binding]; other site
1088720000135	Glucuronate isomerase; Region: UxaC; pfam02614
1088720000136	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
1088720000137	mannonate dehydratase; Region: uxuA; TIGR00695
1088720000138	mannonate dehydratase; Provisional; Region: PRK03906
1088720000139	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
1088720000140	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1088720000141	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1088720000142	O-Glycosyl hydrolase family 30; Region: Glyco_hydro_30; pfam02055
1088720000143	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720000144	putative substrate translocation pore; other site
1088720000145	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1088720000146	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1088720000147	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1088720000148	DNA-binding site [nucleotide binding]; DNA binding site
1088720000149	FCD domain; Region: FCD; pfam07729
1088720000150	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1088720000151	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1088720000152	substrate binding site [chemical binding]; other site
1088720000153	ATP binding site [chemical binding]; other site
1088720000154	Glycosyl hydrolase family 59; Region: Glyco_hydro_59; pfam02057
1088720000155	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
1088720000156	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720000157	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1088720000158	putative substrate translocation pore; other site
1088720000159	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720000160	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1088720000161	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1088720000162	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1088720000163	MMPL family; Region: MMPL; pfam03176
1088720000164	X-X-X-Leu-X-X-Gly heptad repeats; Region: xxxLxxG_by_4; TIGR03057
1088720000165	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1088720000166	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1088720000167	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1088720000168	N-ethylammeline chlorohydrolase; Provisional; Region: PRK07228
1088720000169	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1088720000170	active site
1088720000171	putative diguanylate cyclase; Provisional; Region: PRK09776
1088720000172	Protein of unknown function (DUF3100); Region: DUF3100; pfam11299
1088720000173	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1088720000174	dimer interface [polypeptide binding]; other site
1088720000175	conserved gate region; other site
1088720000176	putative PBP binding loops; other site
1088720000177	ABC-ATPase subunit interface; other site
1088720000178	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1088720000179	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1088720000180	dimer interface [polypeptide binding]; other site
1088720000181	conserved gate region; other site
1088720000182	putative PBP binding loops; other site
1088720000183	ABC-ATPase subunit interface; other site
1088720000184	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
1088720000185	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
1088720000186	Walker A/P-loop; other site
1088720000187	ATP binding site [chemical binding]; other site
1088720000188	Q-loop/lid; other site
1088720000189	ABC transporter signature motif; other site
1088720000190	Walker B; other site
1088720000191	D-loop; other site
1088720000192	H-loop/switch region; other site
1088720000193	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
1088720000194	heavy metal translocating P-type ATPase; Region: ATPase-IB_hvy; TIGR01525
1088720000195	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1088720000196	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1088720000197	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1088720000198	metal-binding site [ion binding]
1088720000199	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cl00264
1088720000200	dinuclear metal binding motif [ion binding]; other site
1088720000201	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1088720000202	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1088720000203	ligand binding site [chemical binding]; other site
1088720000204	flexible hinge region; other site
1088720000205	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1088720000206	putative switch regulator; other site
1088720000207	non-specific DNA interactions [nucleotide binding]; other site
1088720000208	DNA binding site [nucleotide binding]
1088720000209	sequence specific DNA binding site [nucleotide binding]; other site
1088720000210	putative cAMP binding site [chemical binding]; other site
1088720000211	CAAX protease self-immunity; Region: Abi; pfam02517
1088720000212	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1088720000213	active site
1088720000214	P-loop; other site
1088720000215	phosphorylation site [posttranslational modification]
1088720000216	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1088720000217	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1088720000218	active site
1088720000219	phosphorylation site [posttranslational modification]
1088720000220	alpha-mannosidase; Provisional; Region: PRK09819
1088720000221	N-terminal catalytic domain of Escherichia coli alpha-mannosidase MngB and its bacterial homologs; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_EcMngB_like; cd10815
1088720000222	active site
1088720000223	metal binding site [ion binding]; metal-binding site
1088720000224	catalytic site [active]
1088720000225	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; cl08536
1088720000226	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1088720000227	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1088720000228	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1088720000229	putative active site [active]
1088720000230	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1088720000231	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1088720000232	nucleotide binding site [chemical binding]; other site
1088720000233	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
1088720000234	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
1088720000235	substrate binding site [chemical binding]; other site
1088720000236	active site
1088720000237	catalytic residues [active]
1088720000238	heterodimer interface [polypeptide binding]; other site
1088720000239	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
1088720000240	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
1088720000241	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1088720000242	catalytic residue [active]
1088720000243	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
1088720000244	active site
1088720000245	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
1088720000246	active site
1088720000247	ribulose/triose binding site [chemical binding]; other site
1088720000248	phosphate binding site [ion binding]; other site
1088720000249	substrate (anthranilate) binding pocket [chemical binding]; other site
1088720000250	product (indole) binding pocket [chemical binding]; other site
1088720000251	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
1088720000252	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1088720000253	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1088720000254	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720000255	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1088720000256	putative substrate translocation pore; other site
1088720000257	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720000258	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1088720000259	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1088720000260	Catalytic domain of glycoside hydrolase (GH) families 38 and 57, lactam utilization protein LamB/YcsF family proteins, YdjC-family proteins, and similar proteins; Region: GH38-57_N_LamB_YdjC_SF; cl17191
1088720000261	Class I aldolases; Region: Aldolase_Class_I; cl17187
1088720000262	gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Region: galliderm_ABC; TIGR03740
1088720000263	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1088720000264	Walker A/P-loop; other site
1088720000265	ATP binding site [chemical binding]; other site
1088720000266	Q-loop/lid; other site
1088720000267	ABC transporter signature motif; other site
1088720000268	Walker B; other site
1088720000269	D-loop; other site
1088720000270	H-loop/switch region; other site
1088720000271	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1088720000272	non-specific DNA binding site [nucleotide binding]; other site
1088720000273	salt bridge; other site
1088720000274	sequence-specific DNA binding site [nucleotide binding]; other site
1088720000275	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
1088720000276	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; cl17405
1088720000277	dihydrodipicolinate reductase; Provisional; Region: PRK00048
1088720000278	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1088720000279	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1088720000280	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1088720000281	dihydrodipicolinate synthase; Region: dapA; TIGR00674
1088720000282	dimer interface [polypeptide binding]; other site
1088720000283	active site
1088720000284	catalytic residue [active]
1088720000285	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1088720000286	M20 Peptidase Aminoacyclase-1 YkuR-like proteins, including YkuR and Ama/HipO/HyuC proteins; Region: M20_Acy1_YkuR_like; cd05670
1088720000287	metal binding site [ion binding]; metal-binding site
1088720000288	putative dimer interface [polypeptide binding]; other site
1088720000289	Tetrahydrodipicolinate succinyltransferase N-terminal; Region: DapH_N; pfam08503
1088720000290	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Region: DapD_Ac; TIGR03532
1088720000291	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1088720000292	putative trimer interface [polypeptide binding]; other site
1088720000293	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1088720000294	putative CoA binding site [chemical binding]; other site
1088720000295	putative trimer interface [polypeptide binding]; other site
1088720000296	putative CoA binding site [chemical binding]; other site
1088720000297	diaminopimelate decarboxylase; Region: lysA; TIGR01048
1088720000298	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
1088720000299	active site
1088720000300	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1088720000301	substrate binding site [chemical binding]; other site
1088720000302	catalytic residues [active]
1088720000303	dimer interface [polypeptide binding]; other site
1088720000304	aspartate kinase; Reviewed; Region: PRK09034
1088720000305	AAK_AKiii-YclM-BS: Amino Acid Kinase Superfamily (AAK), AKiii-YclM-BS; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII, a monofunctional class enzyme found in...; Region: AAK_AKiii-YclM-BS; cd04245
1088720000306	putative catalytic residues [active]
1088720000307	putative nucleotide binding site [chemical binding]; other site
1088720000308	putative aspartate binding site [chemical binding]; other site
1088720000309	ACT domains located C-terminal to the catalytic domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-YclM-BS_1; cd04911
1088720000310	allosteric regulatory residue; other site
1088720000311	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1088720000312	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
1088720000313	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1088720000314	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1088720000315	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
1088720000316	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1088720000317	Peptidase M15; Region: Peptidase_M15_3; cl01194
1088720000318	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
1088720000319	nudix motif; other site
1088720000320	EamA-like transporter family; Region: EamA; pfam00892
1088720000321	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1088720000322	tetracycline repressor protein TetR; Provisional; Region: PRK13756
1088720000323	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1088720000324	Tetracyclin repressor, C-terminal all-alpha domain; Region: TetR_C; pfam02909
1088720000325	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1088720000326	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
1088720000327	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1088720000328	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1088720000329	Walker A/P-loop; other site
1088720000330	ATP binding site [chemical binding]; other site
1088720000331	Q-loop/lid; other site
1088720000332	ABC transporter signature motif; other site
1088720000333	Walker B; other site
1088720000334	D-loop; other site
1088720000335	H-loop/switch region; other site
1088720000336	Class III nucleotidyl cyclases; Region: Nucleotidyl_cyc_III; cl11967
1088720000337	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
1088720000338	DHH family; Region: DHH; pfam01368
1088720000339	DHHA1 domain; Region: DHHA1; pfam02272
1088720000340	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1088720000341	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1088720000342	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1088720000343	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1088720000344	replicative DNA helicase; Provisional; Region: PRK05748
1088720000345	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1088720000346	Walker A motif; other site
1088720000347	ATP binding site [chemical binding]; other site
1088720000348	Walker B motif; other site
1088720000349	DNA binding loops [nucleotide binding]
1088720000350	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
1088720000351	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1088720000352	active site turn [active]
1088720000353	phosphorylation site [posttranslational modification]
1088720000354	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1088720000355	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
1088720000356	HPr interaction site; other site
1088720000357	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1088720000358	active site
1088720000359	phosphorylation site [posttranslational modification]
1088720000360	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
1088720000361	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
1088720000362	putative active site [active]
1088720000363	Uncharacterized conserved protein [Function unknown]; Region: COG3589
1088720000364	Bacterial protein of unknown function (DUF871); Region: DUF871; pfam05913
1088720000365	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1088720000366	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1088720000367	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1088720000368	putative active site [active]
1088720000369	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1088720000370	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1088720000371	Transcriptional regulator C-terminal region; Region: TetR_C_8; pfam14278
1088720000372	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1088720000373	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1088720000374	Walker A/P-loop; other site
1088720000375	ATP binding site [chemical binding]; other site
1088720000376	Q-loop/lid; other site
1088720000377	ABC transporter signature motif; other site
1088720000378	Walker B; other site
1088720000379	D-loop; other site
1088720000380	H-loop/switch region; other site
1088720000381	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1088720000382	FtsX-like permease family; Region: FtsX; pfam02687
1088720000383	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1088720000384	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1088720000385	FtsX-like permease family; Region: FtsX; pfam02687
1088720000386	Amidohydrolase; Region: Amidohydro_2; pfam04909
1088720000387	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
1088720000388	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
1088720000389	GDP-binding site [chemical binding]; other site
1088720000390	ACT binding site; other site
1088720000391	IMP binding site; other site
1088720000392	heavy metal translocating P-type ATPase; Region: ATPase-IB_hvy; TIGR01525
1088720000393	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1088720000394	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
1088720000395	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1088720000396	dimerization interface [polypeptide binding]; other site
1088720000397	putative DNA binding site [nucleotide binding]; other site
1088720000398	putative Zn2+ binding site [ion binding]; other site
1088720000399	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1088720000400	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1088720000401	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1088720000402	non-specific DNA binding site [nucleotide binding]; other site
1088720000403	salt bridge; other site
1088720000404	sequence-specific DNA binding site [nucleotide binding]; other site
1088720000405	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1088720000406	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720000407	Walker A/P-loop; other site
1088720000408	ATP binding site [chemical binding]; other site
1088720000409	Q-loop/lid; other site
1088720000410	ABC transporter signature motif; other site
1088720000411	Walker B; other site
1088720000412	D-loop; other site
1088720000413	H-loop/switch region; other site
1088720000414	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
1088720000415	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
1088720000416	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
1088720000417	ATP cone domain; Region: ATP-cone; pfam03477
1088720000418	Class III ribonucleotide reductase; Region: RNR_III; cd01675
1088720000419	effector binding site; other site
1088720000420	active site
1088720000421	Zn binding site [ion binding]; other site
1088720000422	glycine loop; other site
1088720000423	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1088720000424	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1088720000425	non-specific DNA binding site [nucleotide binding]; other site
1088720000426	salt bridge; other site
1088720000427	sequence-specific DNA binding site [nucleotide binding]; other site
1088720000428	PAP2_like_6 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which mainly contains bacterial proteins, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_6; cd03396
1088720000429	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1088720000430	active site
1088720000431	Microcin C7 self-immunity protein determines resistance to exogenous microcin C7; Region: Peptidase_S66_mccF_like; cd07062
1088720000432	putative dimer interface [polypeptide binding]; other site
1088720000433	catalytic triad [active]
1088720000434	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
1088720000435	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1088720000436	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1088720000437	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1088720000438	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720000439	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1088720000440	HAMP domain; Region: HAMP; pfam00672
1088720000441	dimerization interface [polypeptide binding]; other site
1088720000442	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1088720000443	dimer interface [polypeptide binding]; other site
1088720000444	phosphorylation site [posttranslational modification]
1088720000445	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1088720000446	ATP binding site [chemical binding]; other site
1088720000447	Mg2+ binding site [ion binding]; other site
1088720000448	G-X-G motif; other site
1088720000449	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1088720000450	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1088720000451	active site
1088720000452	phosphorylation site [posttranslational modification]
1088720000453	intermolecular recognition site; other site
1088720000454	dimerization interface [polypeptide binding]; other site
1088720000455	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1088720000456	DNA binding site [nucleotide binding]
1088720000457	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1088720000458	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1088720000459	DNA binding site [nucleotide binding]
1088720000460	active site
1088720000461	D-Lactate dehydrogenase and D-2-Hydroxyisocaproic acid dehydrogenase (D-HicDH), NAD-binding and catalytic domains; Region: LDH; cd12186
1088720000462	D-lactate dehydrogenase; Validated; Region: PRK08605
1088720000463	homodimer interface [polypeptide binding]; other site
1088720000464	ligand binding site [chemical binding]; other site
1088720000465	NAD binding site [chemical binding]; other site
1088720000466	catalytic site [active]
1088720000467	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1088720000468	active site
1088720000469	P-loop; other site
1088720000470	phosphorylation site [posttranslational modification]
1088720000471	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1088720000472	active site
1088720000473	methionine cluster; other site
1088720000474	phosphorylation site [posttranslational modification]
1088720000475	metal binding site [ion binding]; metal-binding site
1088720000476	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1088720000477	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1088720000478	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
1088720000479	beta-galactosidase; Region: BGL; TIGR03356
1088720000480	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1088720000481	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1088720000482	DNA-binding site [nucleotide binding]; DNA binding site
1088720000483	UTRA domain; Region: UTRA; pfam07702
1088720000484	Protein of unknown function (DUF1304); Region: DUF1304; pfam06993
1088720000485	Protein of unknown function (DUF1516); Region: DUF1516; pfam07457
1088720000486	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1088720000487	DsrE/DsrF-like family; Region: DrsE; cl00672
1088720000488	N-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_N_like; cd08346
1088720000489	Zn binding site [ion binding]; other site
1088720000490	C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_C_like; cd08347
1088720000491	Zn binding site [ion binding]; other site
1088720000492	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1088720000493	WxL domain surface cell wall-binding; Region: WxL; pfam13731
1088720000494	Bacterial protein of unknown function (DUF916); Region: DUF916; pfam06030
1088720000495	Protein of unknown function C-terminal (DUF3324); Region: DUF3324; pfam11797
1088720000496	Mga helix-turn-helix domain; Region: Mga; pfam05043
1088720000497	Protein of unknown function (DUF805); Region: DUF805; pfam05656
1088720000498	Protein of unknown function (DUF805); Region: DUF805; pfam05656
1088720000499	recombination factor protein RarA; Reviewed; Region: PRK13342
1088720000500	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1088720000501	Walker A motif; other site
1088720000502	ATP binding site [chemical binding]; other site
1088720000503	Walker B motif; other site
1088720000504	arginine finger; other site
1088720000505	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
1088720000506	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
1088720000507	propionate/acetate kinase; Provisional; Region: PRK12379
1088720000508	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1088720000509	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
1088720000510	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1088720000511	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
1088720000512	FGGY family of carbohydrate kinases; Region: FGGY; cd00366
1088720000513	N- and C-terminal domain interface [polypeptide binding]; other site
1088720000514	active site
1088720000515	MgATP binding site [chemical binding]; other site
1088720000516	catalytic site [active]
1088720000517	metal binding site [ion binding]; metal-binding site
1088720000518	carbohydrate binding site [chemical binding]; other site
1088720000519	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1088720000520	intersubunit interface [polypeptide binding]; other site
1088720000521	active site
1088720000522	zinc binding site [ion binding]; other site
1088720000523	Na+ binding site [ion binding]; other site
1088720000524	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK09410
1088720000525	phosphoprotein phosphatases of the metallophosphatase superfamily, metallophosphatase domain; Region: MPP_PPP_family; cd00144
1088720000526	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1088720000527	active site
1088720000528	metal binding site [ion binding]; metal-binding site
1088720000529	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1088720000530	endonuclease III; Region: ENDO3c; smart00478
1088720000531	minor groove reading motif; other site
1088720000532	helix-hairpin-helix signature motif; other site
1088720000533	substrate binding pocket [chemical binding]; other site
1088720000534	active site
1088720000535	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720000536	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1088720000537	putative substrate translocation pore; other site
1088720000538	gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Region: galliderm_ABC; TIGR03740
1088720000539	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720000540	Walker A/P-loop; other site
1088720000541	ATP binding site [chemical binding]; other site
1088720000542	Q-loop/lid; other site
1088720000543	ABC transporter signature motif; other site
1088720000544	Walker B; other site
1088720000545	D-loop; other site
1088720000546	H-loop/switch region; other site
1088720000547	putative phosphoketolase; Provisional; Region: PRK05261
1088720000548	Thiamine pyrophosphate (TPP) family, Phosphoketolase (PK) subfamily, TPP-binding module; PK catalyzes the conversion of D-xylulose 5-phosphate and phosphate to acetyl phosphate, D-glyceraldehyde-3-phosphate and H2O. This enzyme requires divalent...; Region: TPP_PK; cd02011
1088720000549	TPP-binding site; other site
1088720000550	XFP C-terminal domain; Region: XFP_C; pfam09363
1088720000551	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1088720000552	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1088720000553	peptide binding site [polypeptide binding]; other site
1088720000554	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720000555	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1088720000556	Walker A/P-loop; other site
1088720000557	ATP binding site [chemical binding]; other site
1088720000558	Q-loop/lid; other site
1088720000559	ABC transporter signature motif; other site
1088720000560	Walker B; other site
1088720000561	D-loop; other site
1088720000562	H-loop/switch region; other site
1088720000563	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
1088720000564	nudix motif; other site
1088720000565	FAD-NAD(P)-binding; Region: NAD_binding_9; pfam13454
1088720000566	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
1088720000567	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1088720000568	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1088720000569	Repair protein; Region: Repair_PSII; pfam04536
1088720000570	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1088720000571	Protein of unknown function (DUF1634); Region: DUF1634; pfam07843
1088720000572	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1088720000573	Putative D-isomer specific 2-hydroxyacid dehydrogenases, NAD-binding and catalytic domains; Region: 2-Hacid_dh_13; cd12178
1088720000574	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
1088720000575	putative ligand binding site [chemical binding]; other site
1088720000576	putative NAD binding site [chemical binding]; other site
1088720000577	catalytic site [active]
1088720000578	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
1088720000579	Transglycosylase associated protein; Region: Transgly_assoc; cl00978
1088720000580	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
1088720000581	Small integral membrane protein (DUF2273); Region: DUF2273; pfam10031
1088720000582	Asp23 family; Region: Asp23; pfam03780
1088720000583	Asp23 family; Region: Asp23; pfam03780
1088720000584	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG1011
1088720000585	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1088720000586	motif II; other site
1088720000587	Protein of unknown function (DUF969); Region: DUF969; pfam06149
1088720000588	Predicted membrane protein [Function unknown]; Region: COG3817
1088720000589	Protein of unknown function (DUF979); Region: DUF979; pfam06166
1088720000590	Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I:  Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from...; Region: Peptidase_C15; cd00501
1088720000591	putative substrate binding pocket [chemical binding]; other site
1088720000592	AC domain interface; other site
1088720000593	catalytic triad [active]
1088720000594	AB domain interface; other site
1088720000595	interchain disulfide; other site
1088720000596	Predicted dinucleotide-binding enzymes [General function prediction only]; Region: COG2085
1088720000597	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; pfam03807
1088720000598	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
1088720000599	catalytic triad [active]
1088720000600	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
1088720000601	16S rRNA methyltransferase GidB; Reviewed; Region: gidB; PRK00107
1088720000602	nucleoid occlusion protein; Region: nucleoid_noc; TIGR04285
1088720000603	ParB-like nuclease domain; Region: ParBc; pfam02195
1088720000604	KorB domain; Region: KorB; pfam08535
1088720000605	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1088720000606	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1088720000607	P-loop; other site
1088720000608	Magnesium ion binding site [ion binding]; other site
1088720000609	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1088720000610	Magnesium ion binding site [ion binding]; other site
1088720000611	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
1088720000612	ParB-like nuclease domain; Region: ParB; smart00470
1088720000613	KorB domain; Region: KorB; pfam08535
1088720000614	Bacterial protein of unknown function (DUF951); Region: DUF951; pfam06107
1088720000615	GTP-binding protein YchF; Reviewed; Region: PRK09601
1088720000616	YchF GTPase; Region: YchF; cd01900
1088720000617	G1 box; other site
1088720000618	GTP/Mg2+ binding site [chemical binding]; other site
1088720000619	Switch I region; other site
1088720000620	G2 box; other site
1088720000621	Switch II region; other site
1088720000622	G3 box; other site
1088720000623	G4 box; other site
1088720000624	G5 box; other site
1088720000625	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1088720000626	Protein of unknown function (DUF1129); Region: DUF1129; pfam06570
1088720000627	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
1088720000628	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1088720000629	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
1088720000630	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1088720000631	active site
1088720000632	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1088720000633	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1088720000634	active site
1088720000635	phosphorylation site [posttranslational modification]
1088720000636	intermolecular recognition site; other site
1088720000637	dimerization interface [polypeptide binding]; other site
1088720000638	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1088720000639	DNA binding site [nucleotide binding]
1088720000640	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1088720000641	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1088720000642	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1088720000643	dimer interface [polypeptide binding]; other site
1088720000644	phosphorylation site [posttranslational modification]
1088720000645	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1088720000646	ATP binding site [chemical binding]; other site
1088720000647	Mg2+ binding site [ion binding]; other site
1088720000648	G-X-G motif; other site
1088720000649	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
1088720000650	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1088720000651	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; cl06814
1088720000652	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1088720000653	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1088720000654	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1088720000655	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1088720000656	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1088720000657	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1088720000658	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1088720000659	aspartate racemase; Region: asp_race; TIGR00035
1088720000660	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
1088720000661	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1088720000662	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1088720000663	active site
1088720000664	catalytic tetrad [active]
1088720000665	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1088720000666	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
1088720000667	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1088720000668	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
1088720000669	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720000670	putative substrate translocation pore; other site
1088720000671	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720000672	Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2; Region: ALDH_F6_MMSDH; cd07085
1088720000673	methylmalonic acid semialdehyde dehydrogenase; Region: MMSDH; TIGR01722
1088720000674	tetrameric interface [polypeptide binding]; other site
1088720000675	NAD binding site [chemical binding]; other site
1088720000676	catalytic residues [active]
1088720000677	Uncharacterized enzyme involved in inositol metabolism [Carbohydrate transport and metabolism]; Region: IolB; COG3718
1088720000678	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1088720000679	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1088720000680	substrate binding site [chemical binding]; other site
1088720000681	ATP binding site [chemical binding]; other site
1088720000682	Acetolactate synthase [Amino acid transport and metabolism]; Region: COG3962
1088720000683	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1088720000684	PYR/PP interface [polypeptide binding]; other site
1088720000685	dimer interface [polypeptide binding]; other site
1088720000686	TPP binding site [chemical binding]; other site
1088720000687	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1088720000688	Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins similar to Rhizobium leguminosarum bv. viciae IolD. IolD plays an important role in myo-inositol catabolism; Region: TPP_IolD; cd02003
1088720000689	TPP-binding site; other site
1088720000690	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1088720000691	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1088720000692	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1088720000693	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1088720000694	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1088720000695	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1088720000696	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1088720000697	intersubunit interface [polypeptide binding]; other site
1088720000698	active site
1088720000699	zinc binding site [ion binding]; other site
1088720000700	Na+ binding site [ion binding]; other site
1088720000701	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235
1088720000702	Predicted sugar epimerase [Carbohydrate transport and metabolism]; Region: COG4130
1088720000703	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1088720000704	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1088720000705	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1088720000706	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1088720000707	putative active site [active]
1088720000708	Predicted 6-phosphogluconate dehydrogenase [Carbohydrate transport and metabolism]; Region: Gnd; COG1023
1088720000709	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1088720000710	gluconate kinase, FGGY type; Region: gntK_FGGY; TIGR01314
1088720000711	Gluconate kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_GntK; cd07770
1088720000712	N- and C-terminal domain interface [polypeptide binding]; other site
1088720000713	active site
1088720000714	catalytic site [active]
1088720000715	metal binding site [ion binding]; metal-binding site
1088720000716	carbohydrate binding site [chemical binding]; other site
1088720000717	ATP binding site [chemical binding]; other site
1088720000718	GntP family permease; Region: GntP_permease; pfam02447
1088720000719	fructuronate transporter; Provisional; Region: PRK10034; cl15264
1088720000720	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1088720000721	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1088720000722	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1088720000723	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cl00462
1088720000724	putative PBP binding regions; other site
1088720000725	ABC-ATPase subunit  interface; other site
1088720000726	Calcineurin-like phosphoesterase superfamily domain; Region: Metallophos_2; pfam12850
1088720000727	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1088720000728	active site
1088720000729	metal binding site [ion binding]; metal-binding site
1088720000730	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
1088720000731	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1088720000732	oligoendopeptidase F; Region: pepF; TIGR00181
1088720000733	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_3; cd09608
1088720000734	active site
1088720000735	Zn binding site [ion binding]; other site
1088720000736	Cell envelope-related transcriptional attenuator domain; Region: LytR_cpsA_psr; cl00581
1088720000737	Branched-chain amino acid transport protein; Region: Branch_AA_trans; cl00547
1088720000738	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1088720000739	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1088720000740	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1088720000741	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1088720000742	active site
1088720000743	Protein of unknown function (DUF975); Region: DUF975; cl10504
1088720000744	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
1088720000745	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1088720000746	Catalytic site [active]
1088720000747	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1088720000748	ADP-ribosylglycohydrolase; Region: ADP_ribosyl_GH; pfam03747
1088720000749	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1088720000750	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1088720000751	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1088720000752	ABC transporter; Region: ABC_tran_2; pfam12848
1088720000753	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1088720000754	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1088720000755	S-adenosylmethionine binding site [chemical binding]; other site
1088720000756	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1088720000757	Uncharacterized conserved protein [Function unknown]; Region: COG2966
1088720000758	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
1088720000759	Protein of unknown function (DUF3815); Region: DUF3815; pfam12821
1088720000760	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1088720000761	Type I periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_ligand_binding_like_12; cd06347
1088720000762	putative ligand binding site [chemical binding]; other site
1088720000763	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1088720000764	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
1088720000765	TM-ABC transporter signature motif; other site
1088720000766	ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177
1088720000767	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
1088720000768	TM-ABC transporter signature motif; other site
1088720000769	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
1088720000770	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
1088720000771	Walker A/P-loop; other site
1088720000772	ATP binding site [chemical binding]; other site
1088720000773	Q-loop/lid; other site
1088720000774	ABC transporter signature motif; other site
1088720000775	Walker B; other site
1088720000776	D-loop; other site
1088720000777	H-loop/switch region; other site
1088720000778	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
1088720000779	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
1088720000780	Walker A/P-loop; other site
1088720000781	ATP binding site [chemical binding]; other site
1088720000782	Q-loop/lid; other site
1088720000783	ABC transporter signature motif; other site
1088720000784	Walker B; other site
1088720000785	D-loop; other site
1088720000786	H-loop/switch region; other site
1088720000787	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain superfamily; Region: NTP-PPase; cd11523
1088720000788	metal binding site [ion binding]; metal-binding site
1088720000789	Alpha/beta hydrolase of unknown function (DUF915); Region: DUF915; pfam06028
1088720000790	PGAP1-like protein; Region: PGAP1; pfam07819
1088720000791	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1088720000792	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
1088720000793	intersubunit interface [polypeptide binding]; other site
1088720000794	active site
1088720000795	catalytic residue [active]
1088720000796	phosphopentomutase; Provisional; Region: PRK05362
1088720000797	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
1088720000798	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
1088720000799	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1088720000800	NlpC/P60 family; Region: NLPC_P60; pfam00877
1088720000801	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
1088720000802	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1088720000803	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; cl17295
1088720000804	PTS_IIB_lactose: subunit IIB of enzyme II (EII) of the lactose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS) found in Firmicutes as well as Actinobacteria. In this system, EII is a lactose-specific permease with two...; Region: PTS_IIB_lactose; cd05565
1088720000805	active site
1088720000806	P-loop; other site
1088720000807	phosphorylation site [posttranslational modification]
1088720000808	transcriptional antiterminator BglG; Provisional; Region: PRK09772
1088720000809	CAT RNA binding domain; Region: CAT_RBD; pfam03123
1088720000810	PRD domain; Region: PRD; pfam00874
1088720000811	PRD domain; Region: PRD; pfam00874
1088720000812	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1088720000813	methionine cluster; other site
1088720000814	active site
1088720000815	phosphorylation site [posttranslational modification]
1088720000816	metal binding site [ion binding]; metal-binding site
1088720000817	6-phospho-beta-galactosidase; Provisional; Region: PRK13511
1088720000818	beta-galactosidase; Region: BGL; TIGR03356
1088720000819	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
1088720000820	DEAD/DEAH box helicase; Region: DEAD; pfam00270
1088720000821	DEAD_2; Region: DEAD_2; pfam06733
1088720000822	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1088720000823	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1088720000824	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1088720000825	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1088720000826	M protein trans-acting positive regulator (MGA) HTH domain; Region: HTH_Mga; pfam08280
1088720000827	HTH domain; Region: HTH_11; cl17392
1088720000828	PRD domain; Region: PRD; pfam00874
1088720000829	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1088720000830	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1088720000831	active site
1088720000832	phosphorylation site [posttranslational modification]
1088720000833	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1088720000834	active site
1088720000835	phosphorylation site [posttranslational modification]
1088720000836	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1088720000837	putative PTS system  transporter subunits IIBC; Provisional; Region: PRK11404
1088720000838	active site
1088720000839	P-loop; other site
1088720000840	phosphorylation site [posttranslational modification]
1088720000841	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1088720000842	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
1088720000843	mannose-6-phosphate isomerase, class I; Region: manA; TIGR00218
1088720000844	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1088720000845	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1088720000846	DNA-binding site [nucleotide binding]; DNA binding site
1088720000847	UTRA domain; Region: UTRA; pfam07702
1088720000848	putative sugar isomerase, AgaS family; Region: agaS_fam; TIGR02815
1088720000849	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1088720000850	dimer interface [polypeptide binding]; other site
1088720000851	active site
1088720000852	AgaS-like protein. AgaS contains a SIS (Sugar ISomerase) domain which is found in many phosphosugar isomerases and phosphosugar binding proteins. AgaS is a putative isomerase in Escherichia coli. It is similar to the glucosamine-6-phosphate synthases; Region: SIS_AgaS_like; cd05010
1088720000853	putative active site [active]
1088720000854	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
1088720000855	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
1088720000856	active site
1088720000857	dimer interface [polypeptide binding]; other site
1088720000858	Glycosyl hydrolases family 35; Region: Glyco_hydro_35; pfam01301
1088720000859	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1088720000860	active site
1088720000861	phosphorylation site [posttranslational modification]
1088720000862	PTS system sorbose-specific iic component; Region: EII-Sor; pfam03609
1088720000863	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
1088720000864	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1088720000865	active pocket/dimerization site; other site
1088720000866	active site
1088720000867	phosphorylation site [posttranslational modification]
1088720000868	Domain of unknown function (DUF1975); Region: DUF1975; pfam09318
1088720000869	This family is most closely related to the GT1 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding.  In...; Region: GT1_gtfA_like; cd04949
1088720000870	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1088720000871	Domain of unknown function (DUF1975); Region: DUF1975; pfam09318
1088720000872	This family is most closely related to the GT1 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding.  In...; Region: GT1_gtfA_like; cd04949
1088720000873	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1088720000874	Rap/ran-GAP; Region: Rap_GAP; pfam02145
1088720000875	Uncharacterized protein conserved in bacteria (DUF2325); Region: DUF2325; pfam10087
1088720000876	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
1088720000877	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1088720000878	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1088720000879	homodimer interface [polypeptide binding]; other site
1088720000880	catalytic residue [active]
1088720000881	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1088720000882	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
1088720000883	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
1088720000884	active site
1088720000885	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1088720000886	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1088720000887	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1088720000888	active site
1088720000889	P-loop; other site
1088720000890	phosphorylation site [posttranslational modification]
1088720000891	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1088720000892	active site
1088720000893	methionine cluster; other site
1088720000894	phosphorylation site [posttranslational modification]
1088720000895	metal binding site [ion binding]; metal-binding site
1088720000896	exoaminopeptidase; Provisional; Region: PRK09961
1088720000897	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
1088720000898	oligomer interface [polypeptide binding]; other site
1088720000899	active site
1088720000900	metal binding site [ion binding]; metal-binding site
1088720000901	HTH domain; Region: HTH_11; pfam08279
1088720000902	PRD domain; Region: PRD; pfam00874
1088720000903	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1088720000904	active site
1088720000905	P-loop; other site
1088720000906	phosphorylation site [posttranslational modification]
1088720000907	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1088720000908	active site
1088720000909	phosphorylation site [posttranslational modification]
1088720000910	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
1088720000911	peptidase T; Region: peptidase-T; TIGR01882
1088720000912	metal binding site [ion binding]; metal-binding site
1088720000913	dimer interface [polypeptide binding]; other site
1088720000914	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1088720000915	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1088720000916	peptide binding site [polypeptide binding]; other site
1088720000917	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1088720000918	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1088720000919	Coenzyme A binding pocket [chemical binding]; other site
1088720000920	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720000921	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1088720000922	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1088720000923	Walker A/P-loop; other site
1088720000924	ATP binding site [chemical binding]; other site
1088720000925	Q-loop/lid; other site
1088720000926	ABC transporter signature motif; other site
1088720000927	Rhomboid family; Region: Rhomboid; cl11446
1088720000928	Rhomboid family; Region: Rhomboid; cl11446
1088720000929	ABC-type cobalt transport system, permease component; Region: ABC_cobalt; cl01943
1088720000930	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1088720000931	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1088720000932	Walker A/P-loop; other site
1088720000933	ATP binding site [chemical binding]; other site
1088720000934	Q-loop/lid; other site
1088720000935	ABC transporter signature motif; other site
1088720000936	Walker B; other site
1088720000937	D-loop; other site
1088720000938	H-loop/switch region; other site
1088720000939	ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones]; Region: CcmA; COG4133
1088720000940	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1088720000941	Walker A/P-loop; other site
1088720000942	ATP binding site [chemical binding]; other site
1088720000943	Q-loop/lid; other site
1088720000944	ABC transporter signature motif; other site
1088720000945	Walker B; other site
1088720000946	D-loop; other site
1088720000947	H-loop/switch region; other site
1088720000948	Putative transcription activator [Transcription]; Region: TenA; COG0819
1088720000949	Thiamine-precursor transporter protein (ThiW); Region: ThiW; pfam09512
1088720000950	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
1088720000951	substrate binding site [chemical binding]; other site
1088720000952	multimerization interface [polypeptide binding]; other site
1088720000953	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
1088720000954	ATP binding site [chemical binding]; other site
1088720000955	substrate binding site [chemical binding]; other site
1088720000956	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1088720000957	thiamine phosphate binding site [chemical binding]; other site
1088720000958	active site
1088720000959	pyrophosphate binding site [ion binding]; other site
1088720000960	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
1088720000961	dimer interface [polypeptide binding]; other site
1088720000962	substrate binding site [chemical binding]; other site
1088720000963	ATP binding site [chemical binding]; other site
1088720000964	Amino acid permease; Region: AA_permease_2; pfam13520
1088720000965	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1088720000966	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1088720000967	DNA binding site [nucleotide binding]
1088720000968	domain linker motif; other site
1088720000969	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1088720000970	ligand binding site [chemical binding]; other site
1088720000971	dimerization interface [polypeptide binding]; other site
1088720000972	D-ribose pyranase; Provisional; Region: PRK11797
1088720000973	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1088720000974	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1088720000975	Walker A/P-loop; other site
1088720000976	ATP binding site [chemical binding]; other site
1088720000977	Q-loop/lid; other site
1088720000978	ABC transporter signature motif; other site
1088720000979	Walker B; other site
1088720000980	D-loop; other site
1088720000981	H-loop/switch region; other site
1088720000982	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1088720000983	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1088720000984	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1088720000985	TM-ABC transporter signature motif; other site
1088720000986	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
1088720000987	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
1088720000988	ligand binding site [chemical binding]; other site
1088720000989	dimerization interface [polypeptide binding]; other site
1088720000990	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1088720000991	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1088720000992	substrate binding site [chemical binding]; other site
1088720000993	dimer interface [polypeptide binding]; other site
1088720000994	ATP binding site [chemical binding]; other site
1088720000995	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1088720000996	salt bridge; other site
1088720000997	non-specific DNA binding site [nucleotide binding]; other site
1088720000998	sequence-specific DNA binding site [nucleotide binding]; other site
1088720000999	Rhomboid family; Region: Rhomboid; cl11446
1088720001000	Protein of unknown function (DUF2785); Region: DUF2785; pfam10978
1088720001001	NTF2-like N-terminal transpeptidase domain; Region: MecA_N; pfam05223
1088720001002	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1088720001003	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1088720001004	gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Region: galliderm_ABC; TIGR03740
1088720001005	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720001006	Walker A/P-loop; other site
1088720001007	ATP binding site [chemical binding]; other site
1088720001008	Q-loop/lid; other site
1088720001009	ABC transporter signature motif; other site
1088720001010	Walker B; other site
1088720001011	D-loop; other site
1088720001012	H-loop/switch region; other site
1088720001013	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1088720001014	MarR family; Region: MarR_2; pfam12802
1088720001015	MarR family; Region: MarR_2; cl17246
1088720001016	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1088720001017	PRD domain; Region: PRD; pfam00874
1088720001018	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1088720001019	active site
1088720001020	P-loop; other site
1088720001021	phosphorylation site [posttranslational modification]
1088720001022	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1088720001023	active site
1088720001024	phosphorylation site [posttranslational modification]
1088720001025	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1088720001026	active site
1088720001027	P-loop; other site
1088720001028	phosphorylation site [posttranslational modification]
1088720001029	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: PRK12997
1088720001030	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1088720001031	intersubunit interface [polypeptide binding]; other site
1088720001032	active site
1088720001033	zinc binding site [ion binding]; other site
1088720001034	Na+ binding site [ion binding]; other site
1088720001035	AAA domain; Region: AAA_18; pfam13238
1088720001036	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1088720001037	Walker A motif; other site
1088720001038	ATP binding site [chemical binding]; other site
1088720001039	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
1088720001040	active site
1088720001041	tetramer interface [polypeptide binding]; other site
1088720001042	C4-dicarboxylate transporter [Energy production and conversion]; Region: DcuC; COG3069
1088720001043	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1088720001044	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1088720001045	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1088720001046	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1088720001047	DNA-binding site [nucleotide binding]; DNA binding site
1088720001048	DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes [Carbohydrate transport and metabolism]; Region: FbaB; COG1830
1088720001049	Class I aldolases; Region: Aldolase_Class_I; cl17187
1088720001050	catalytic residue [active]
1088720001051	Glycerol-3-phosphate responsive antiterminator; Region: G3P_antiterm; cl00852
1088720001052	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
1088720001053	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
1088720001054	putative N- and C-terminal domain interface [polypeptide binding]; other site
1088720001055	putative active site [active]
1088720001056	MgATP binding site [chemical binding]; other site
1088720001057	catalytic site [active]
1088720001058	metal binding site [ion binding]; metal-binding site
1088720001059	putative xylulose binding site [chemical binding]; other site
1088720001060	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1088720001061	classical (c) SDRs; Region: SDR_c; cd05233
1088720001062	NAD(P) binding site [chemical binding]; other site
1088720001063	active site
1088720001064	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_10; cd12171
1088720001065	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
1088720001066	putative ligand binding site [chemical binding]; other site
1088720001067	putative NAD binding site [chemical binding]; other site
1088720001068	catalytic site [active]
1088720001069	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
1088720001070	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1088720001071	HTH domain; Region: HTH_11; cl17392
1088720001072	PRD domain; Region: PRD; pfam00874
1088720001073	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cl00163
1088720001074	active site
1088720001075	phosphorylation site [posttranslational modification]
1088720001076	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1088720001077	intersubunit interface [polypeptide binding]; other site
1088720001078	active site
1088720001079	zinc binding site [ion binding]; other site
1088720001080	Na+ binding site [ion binding]; other site
1088720001081	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
1088720001082	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1088720001083	active site
1088720001084	phosphorylation site [posttranslational modification]
1088720001085	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1088720001086	active site
1088720001087	P-loop; other site
1088720001088	phosphorylation site [posttranslational modification]
1088720001089	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1088720001090	L-sorbose-1-phosphate reductase; Region: sorbose_phosphate_red; cd08238
1088720001091	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1088720001092	putative NAD(P) binding site [chemical binding]; other site
1088720001093	catalytic Zn binding site [ion binding]; other site
1088720001094	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
1088720001095	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
1088720001096	sorbitol-6-phosphate 2-dehydrogenase; Provisional; Region: PRK06171
1088720001097	classical (c) SDRs; Region: SDR_c; cd05233
1088720001098	NAD(P) binding site [chemical binding]; other site
1088720001099	active site
1088720001100	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1088720001101	active pocket/dimerization site; other site
1088720001102	active site
1088720001103	phosphorylation site [posttranslational modification]
1088720001104	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1088720001105	active site
1088720001106	phosphorylation site [posttranslational modification]
1088720001107	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
1088720001108	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; cl01507
1088720001109	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1088720001110	intersubunit interface [polypeptide binding]; other site
1088720001111	active site
1088720001112	zinc binding site [ion binding]; other site
1088720001113	Na+ binding site [ion binding]; other site
1088720001114	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1088720001115	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
1088720001116	transmembrane helices; other site
1088720001117	FAD dependent oxidoreductase; Region: FAD_oxidored; pfam12831
1088720001118	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1088720001119	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1088720001120	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1088720001121	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1088720001122	dimerization interface [polypeptide binding]; other site
1088720001123	Uncharacterized conserved protein [Function unknown]; Region: COG1912
1088720001124	hypothetical protein; Provisional; Region: PRK13661
1088720001125	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1088720001126	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1088720001127	Walker A/P-loop; other site
1088720001128	ATP binding site [chemical binding]; other site
1088720001129	Q-loop/lid; other site
1088720001130	ABC transporter signature motif; other site
1088720001131	Walker B; other site
1088720001132	D-loop; other site
1088720001133	H-loop/switch region; other site
1088720001134	ATP-binding cassette cobalt transporter; Region: DUF3744; pfam12558
1088720001135	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1088720001136	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1088720001137	Walker A/P-loop; other site
1088720001138	ATP binding site [chemical binding]; other site
1088720001139	Q-loop/lid; other site
1088720001140	ABC transporter signature motif; other site
1088720001141	Walker B; other site
1088720001142	D-loop; other site
1088720001143	H-loop/switch region; other site
1088720001144	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
1088720001145	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1088720001146	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1088720001147	DNA binding site [nucleotide binding]
1088720001148	domain linker motif; other site
1088720001149	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1088720001150	dimerization interface [polypeptide binding]; other site
1088720001151	ligand binding site [chemical binding]; other site
1088720001152	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1088720001153	Ca binding site [ion binding]; other site
1088720001154	active site
1088720001155	catalytic site [active]
1088720001156	fumarate reductase flavoprotein subunit; Validated; Region: PRK06481
1088720001157	L-aspartate oxidase; Provisional; Region: PRK06175
1088720001158	Predicted oxidoreductase [General function prediction only]; Region: COG3573
1088720001159	hypothetical protein; Provisional; Region: PRK06357
1088720001160	active site
1088720001161	intersubunit interface [polypeptide binding]; other site
1088720001162	Zn2+ binding site [ion binding]; other site
1088720001163	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
1088720001164	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
1088720001165	PTS_IIB: subunit IIB of enzyme II (EII) is the central energy-coupling domain of the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In the multienzyme PTS complex, EII is a carbohydrate-specific permease consisting of two cytoplasmic...; Region: PTS_IIB; cl10014
1088720001166	active site
1088720001167	P-loop; other site
1088720001168	phosphorylation site [posttranslational modification]
1088720001169	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1088720001170	active site
1088720001171	phosphorylation site [posttranslational modification]
1088720001172	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1088720001173	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1088720001174	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1088720001175	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
1088720001176	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1088720001177	putative substrate binding site [chemical binding]; other site
1088720001178	putative ATP binding site [chemical binding]; other site
1088720001179	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1088720001180	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1088720001181	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1088720001182	putative active site [active]
1088720001183	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1088720001184	active site
1088720001185	phosphorylation site [posttranslational modification]
1088720001186	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
1088720001187	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1088720001188	active site
1088720001189	P-loop; other site
1088720001190	phosphorylation site [posttranslational modification]
1088720001191	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
1088720001192	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1088720001193	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1088720001194	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1088720001195	active site
1088720001196	motif I; other site
1088720001197	motif II; other site
1088720001198	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1088720001199	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
1088720001200	Glycoside Hydrolases Family 4; GlvA- and pagL-like glycosidases; Region: GH4_GlvA_pagL_like; cd05298
1088720001201	NAD binding site [chemical binding]; other site
1088720001202	sugar binding site [chemical binding]; other site
1088720001203	divalent metal binding site [ion binding]; other site
1088720001204	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
1088720001205	dimer interface [polypeptide binding]; other site
1088720001206	PTS system, alpha-glucoside-specific IIBC component; Region: PTS-IIBC-alpha; TIGR02005
1088720001207	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1088720001208	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1088720001209	active site turn [active]
1088720001210	phosphorylation site [posttranslational modification]
1088720001211	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1088720001212	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1088720001213	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1088720001214	putative active site [active]
1088720001215	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1088720001216	active site turn [active]
1088720001217	phosphorylation site [posttranslational modification]
1088720001218	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
1088720001219	HPr interaction site; other site
1088720001220	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1088720001221	active site
1088720001222	phosphorylation site [posttranslational modification]
1088720001223	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
1088720001224	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1088720001225	motif II; other site
1088720001226	HAD-hyrolase-like; Region: Hydrolase_like; pfam13242
1088720001227	transcriptional antiterminator BglG; Provisional; Region: PRK09772
1088720001228	CAT RNA binding domain; Region: CAT_RBD; pfam03123
1088720001229	PRD domain; Region: PRD; pfam00874
1088720001230	PRD domain; Region: PRD; pfam00874
1088720001231	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
1088720001232	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1088720001233	active site turn [active]
1088720001234	phosphorylation site [posttranslational modification]
1088720001235	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1088720001236	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1088720001237	HPr interaction site; other site
1088720001238	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1088720001239	active site
1088720001240	phosphorylation site [posttranslational modification]
1088720001241	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
1088720001242	beta-galactosidase; Region: BGL; TIGR03356
1088720001243	HTH domain; Region: HTH_11; pfam08279
1088720001244	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1088720001245	Mga helix-turn-helix domain; Region: Mga; pfam05043
1088720001246	PRD domain; Region: PRD; pfam00874
1088720001247	PRD domain; Region: PRD; pfam00874
1088720001248	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1088720001249	active site
1088720001250	P-loop; other site
1088720001251	phosphorylation site [posttranslational modification]
1088720001252	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cl00163
1088720001253	active site
1088720001254	phosphorylation site [posttranslational modification]
1088720001255	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1088720001256	intersubunit interface [polypeptide binding]; other site
1088720001257	active site
1088720001258	zinc binding site [ion binding]; other site
1088720001259	Na+ binding site [ion binding]; other site
1088720001260	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1088720001261	active site
1088720001262	phosphorylation site [posttranslational modification]
1088720001263	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1088720001264	active site
1088720001265	P-loop; other site
1088720001266	phosphorylation site [posttranslational modification]
1088720001267	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1088720001268	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
1088720001269	Aldose 1-epimerase, similar to Escherichia coli c4013; Region: Aldose_epim_Ec_c4013; cd09023
1088720001270	active site
1088720001271	catalytic residues [active]
1088720001272	Protein of unknown function (DUF1498); Region: DUF1498; cl17840
1088720001273	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
1088720001274	N- and C-terminal domain interface [polypeptide binding]; other site
1088720001275	D-xylulose kinase; Region: XylB; TIGR01312
1088720001276	active site
1088720001277	MgATP binding site [chemical binding]; other site
1088720001278	catalytic site [active]
1088720001279	metal binding site [ion binding]; metal-binding site
1088720001280	xylulose binding site [chemical binding]; other site
1088720001281	homodimer interface [polypeptide binding]; other site
1088720001282	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
1088720001283	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1088720001284	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1088720001285	active site turn [active]
1088720001286	phosphorylation site [posttranslational modification]
1088720001287	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
1088720001288	putative active site [active]
1088720001289	YdjC motif; other site
1088720001290	Mg binding site [ion binding]; other site
1088720001291	putative homodimer interface [polypeptide binding]; other site
1088720001292	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
1088720001293	NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195
1088720001294	NAD(P) binding site [chemical binding]; other site
1088720001295	LDH/MDH dimer interface [polypeptide binding]; other site
1088720001296	substrate binding site [chemical binding]; other site
1088720001297	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1088720001298	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1088720001299	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1088720001300	putative active site [active]
1088720001301	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1088720001302	active site
1088720001303	phosphorylation site [posttranslational modification]
1088720001304	putative PTS system  transporter subunits IIBC; Provisional; Region: PRK11404
1088720001305	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1088720001306	active site
1088720001307	P-loop; other site
1088720001308	phosphorylation site [posttranslational modification]
1088720001309	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1088720001310	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
1088720001311	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1088720001312	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1088720001313	homodimer interface [polypeptide binding]; other site
1088720001314	catalytic residue [active]
1088720001315	putative frv operon regulatory protein; Provisional; Region: PRK09863
1088720001316	HTH domain; Region: HTH_11; pfam08279
1088720001317	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cl00163
1088720001318	active site
1088720001319	phosphorylation site [posttranslational modification]
1088720001320	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1088720001321	putative active site [active]
1088720001322	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1088720001323	active site
1088720001324	phosphorylation site [posttranslational modification]
1088720001325	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1088720001326	active site
1088720001327	P-loop; other site
1088720001328	phosphorylation site [posttranslational modification]
1088720001329	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: PRK12997
1088720001330	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1088720001331	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
1088720001332	inhibitor site; inhibition site
1088720001333	active site
1088720001334	dimer interface [polypeptide binding]; other site
1088720001335	catalytic residue [active]
1088720001336	2-keto-3-deoxy-6-phosphogluconate aldolase [Carbohydrate transport and metabolism]; Region: Eda; COG0800
1088720001337	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1088720001338	active site
1088720001339	intersubunit interface [polypeptide binding]; other site
1088720001340	catalytic residue [active]
1088720001341	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1088720001342	Mga helix-turn-helix domain; Region: Mga; pfam05043
1088720001343	PRD domain; Region: PRD; pfam00874
1088720001344	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1088720001345	active site
1088720001346	P-loop; other site
1088720001347	phosphorylation site [posttranslational modification]
1088720001348	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1088720001349	active site
1088720001350	phosphorylation site [posttranslational modification]
1088720001351	Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer,  utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cl00514
1088720001352	FMN binding site [chemical binding]; other site
1088720001353	dimer interface [polypeptide binding]; other site
1088720001354	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1088720001355	helix_turn_helix, Lux Regulon; Region: HTH_LUXR; smart00421
1088720001356	DNA binding residues [nucleotide binding]
1088720001357	dimerization interface [polypeptide binding]; other site
1088720001358	YvrJ protein family; Region: YvrJ; pfam12841
1088720001359	AtlA is an autolysin found in Gram-positive lactic acid bacteria that degrades bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues. This family includes the AtlA and Aml...; Region: GH25_AtlA-like; cd06522
1088720001360	active site
1088720001361	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
1088720001362	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1088720001363	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1088720001364	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1088720001365	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1088720001366	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1088720001367	FtsX-like permease family; Region: FtsX; pfam02687
1088720001368	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1088720001369	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1088720001370	Walker A/P-loop; other site
1088720001371	ATP binding site [chemical binding]; other site
1088720001372	Q-loop/lid; other site
1088720001373	ABC transporter signature motif; other site
1088720001374	Walker B; other site
1088720001375	D-loop; other site
1088720001376	H-loop/switch region; other site
1088720001377	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
1088720001378	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1088720001379	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1088720001380	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1088720001381	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1088720001382	active site
1088720001383	motif I; other site
1088720001384	motif II; other site
1088720001385	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1088720001386	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041; cl17396
1088720001387	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1088720001388	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1088720001389	DNA binding site [nucleotide binding]
1088720001390	domain linker motif; other site
1088720001391	Ligand-binding domain of a novel transcription factor implicated in catabolite repression in Bacillus and Clostridium species; Region: PBP1_CcpB_like; cd06286
1088720001392	putative dimerization interface [polypeptide binding]; other site
1088720001393	putative ligand binding site [chemical binding]; other site
1088720001394	PTS system sorbose subfamily IIB component; Region: PTSIIB_sorb; pfam03830
1088720001395	active site
1088720001396	phosphorylation site [posttranslational modification]
1088720001397	PTS system sorbose-specific iic component; Region: EII-Sor; pfam03609
1088720001398	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
1088720001399	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
1088720001400	This family represents an uncharacterized glycosyl hydrolase family 31 (GH31) enzyme found in bacteria and eukaryotes that is related to the XylS xylosidase of Sulfolobus solfataricus. Alpha-xylosidases catalyze the release of an alpha-xylose residue...; Region: GH31_xylosidase_XylS-like; cd06595
1088720001401	putative active site [active]
1088720001402	putative catalytic site [active]
1088720001403	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
1088720001404	active pocket/dimerization site; other site
1088720001405	active site
1088720001406	phosphorylation site [posttranslational modification]
1088720001407	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
1088720001408	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1088720001409	Ca binding site [ion binding]; other site
1088720001410	active site
1088720001411	catalytic site [active]
1088720001412	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
1088720001413	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
1088720001414	active site
1088720001415	NTP binding site [chemical binding]; other site
1088720001416	metal binding triad [ion binding]; metal-binding site
1088720001417	Domain of unknown function (DUF4111); Region: DUF4111; pfam13427
1088720001418	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1088720001419	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
1088720001420	Linear amide C-N hydrolases, choloylglycine hydrolase family; Region: CBAH; pfam02275
1088720001421	active site
1088720001422	myosin-cross-reactive antigen; Provisional; Region: PRK13977
1088720001423	probable dihydroxyacetone kinase regulator; Region: DHAK_reg; TIGR02366
1088720001424	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1088720001425	phosphotransferase mannnose-specific family component IIA; Provisional; Region: PRK14484
1088720001426	DAK2 domain; Region: Dak2; cl03685
1088720001427	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK14481
1088720001428	Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Region: DAK1; COG2376
1088720001429	OsmC-like protein; Region: OsmC; cl00767
1088720001430	Rhomboid family; Region: Rhomboid; cl11446
1088720001431	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
1088720001432	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1088720001433	active site
1088720001434	catalytic site [active]
1088720001435	substrate binding site [chemical binding]; other site
1088720001436	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041; cl17396
1088720001437	RelB antitoxin; Region: RelB; cl01171
1088720001438	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1088720001439	dimerization interface [polypeptide binding]; other site
1088720001440	putative DNA binding site [nucleotide binding]; other site
1088720001441	putative Zn2+ binding site [ion binding]; other site
1088720001442	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720001443	benzoate transport; Region: 2A0115; TIGR00895
1088720001444	putative substrate translocation pore; other site
1088720001445	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
1088720001446	Predicted site-specific integrase-resolvase [DNA replication, recombination, and repair]; Region: COG2452
1088720001447	Helix-Turn-Helix DNA binding domain of truncated MerR-like proteins; Region: HTH_MerR-trunc; cd04762
1088720001448	DNA binding residues [nucleotide binding]
1088720001449	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cl02788
1088720001450	catalytic residues [active]
1088720001451	catalytic nucleophile [active]
1088720001452	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
1088720001453	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
1088720001454	Probable transposase; Region: OrfB_IS605; pfam01385
1088720001455	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
1088720001456	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1088720001457	intersubunit interface [polypeptide binding]; other site
1088720001458	active site
1088720001459	zinc binding site [ion binding]; other site
1088720001460	Na+ binding site [ion binding]; other site
1088720001461	pyruvate oxidase; Provisional; Region: PRK08611
1088720001462	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
1088720001463	PYR/PP interface [polypeptide binding]; other site
1088720001464	dimer interface [polypeptide binding]; other site
1088720001465	tetramer interface [polypeptide binding]; other site
1088720001466	TPP binding site [chemical binding]; other site
1088720001467	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1088720001468	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
1088720001469	TPP-binding site [chemical binding]; other site
1088720001470	Beta-lactamase; Region: Beta-lactamase; pfam00144
1088720001471	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1088720001472	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
1088720001473	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
1088720001474	active site
1088720001475	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1088720001476	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1088720001477	S-adenosylmethionine binding site [chemical binding]; other site
1088720001478	Predicted glutamine amidotransferases [General function prediction only]; Region: COG2071
1088720001479	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
1088720001480	catalytic triad [active]
1088720001481	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
1088720001482	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
1088720001483	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
1088720001484	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1088720001485	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1088720001486	Amino acid permease; Region: AA_permease_2; pfam13520
1088720001487	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1088720001488	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
1088720001489	DNA binding residues [nucleotide binding]
1088720001490	putative dimer interface [polypeptide binding]; other site
1088720001491	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1088720001492	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1088720001493	active site
1088720001494	catalytic tetrad [active]
1088720001495	Arginate lyase and other MDR family members; Region: AL_MDR; cd08252
1088720001496	zinc-binding alcohol dehydrogenase family protein; Region: adh_fam_1; TIGR02817
1088720001497	putative NAD(P) binding site [chemical binding]; other site
1088720001498	dimer interface [polypeptide binding]; other site
1088720001499	Predicted transcriptional regulators [Transcription]; Region: COG1733
1088720001500	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1088720001501	hypothetical protein; Provisional; Region: PRK10621
1088720001502	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1088720001503	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1088720001504	gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Region: galliderm_ABC; TIGR03740
1088720001505	Walker A/P-loop; other site
1088720001506	ATP binding site [chemical binding]; other site
1088720001507	Q-loop/lid; other site
1088720001508	ABC transporter signature motif; other site
1088720001509	Walker B; other site
1088720001510	D-loop; other site
1088720001511	H-loop/switch region; other site
1088720001512	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1088720001513	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1088720001514	active site
1088720001515	phosphorylation site [posttranslational modification]
1088720001516	intermolecular recognition site; other site
1088720001517	dimerization interface [polypeptide binding]; other site
1088720001518	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1088720001519	DNA binding site [nucleotide binding]
1088720001520	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1088720001521	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1088720001522	dimerization interface [polypeptide binding]; other site
1088720001523	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1088720001524	dimer interface [polypeptide binding]; other site
1088720001525	phosphorylation site [posttranslational modification]
1088720001526	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1088720001527	ATP binding site [chemical binding]; other site
1088720001528	Mg2+ binding site [ion binding]; other site
1088720001529	G-X-G motif; other site
1088720001530	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1088720001531	ABC-type multidrug transport system, ATPase component; Region: ABC_drug_resistance_like; cd03264
1088720001532	Walker A/P-loop; other site
1088720001533	ATP binding site [chemical binding]; other site
1088720001534	Q-loop/lid; other site
1088720001535	ABC transporter signature motif; other site
1088720001536	Walker B; other site
1088720001537	D-loop; other site
1088720001538	H-loop/switch region; other site
1088720001539	Aminopeptidase N [Amino acid transport and metabolism]; Region: PepN; COG0308
1088720001540	Peptidase M1 Aminopeptidase N family incudes tricorn interacting factor F3, Endoplasmic reticulum aminopeptidase 1 (ERAP1), Aminopeptidase Q (APQ); Region: M1_APN_2; cd09601
1088720001541	Zn binding site [ion binding]; other site
1088720001542	inner membrane transporter YjeM; Provisional; Region: PRK15238
1088720001543	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1088720001544	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
1088720001545	Protein of unknown function (DUF1440); Region: DUF1440; pfam07274
1088720001546	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
1088720001547	proposed active site lysine [active]
1088720001548	conserved cys residue [active]
1088720001549	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1088720001550	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1088720001551	dimer interface [polypeptide binding]; other site
1088720001552	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1088720001553	catalytic residue [active]
1088720001554	Cys/Met metabolism PLP-dependent enzyme; Region: Cys_Met_Meta_PP; pfam01053
1088720001555	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1088720001556	homodimer interface [polypeptide binding]; other site
1088720001557	substrate-cofactor binding pocket; other site
1088720001558	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1088720001559	catalytic residue [active]
1088720001560	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1088720001561	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1088720001562	dimer interface [polypeptide binding]; other site
1088720001563	conserved gate region; other site
1088720001564	putative PBP binding loops; other site
1088720001565	ABC-ATPase subunit interface; other site
1088720001566	Branched-chain amino acid transport protein; Region: Branch_AA_trans; cl00547
1088720001567	WxL domain surface cell wall-binding; Region: WxL; pfam13731
1088720001568	Bacterial protein of unknown function (DUF916); Region: DUF916; pfam06030
1088720001569	Protein of unknown function C-terminal (DUF3324); Region: DUF3324; pfam11797
1088720001570	legume lectins; Region: lectin_L-type; cd01951
1088720001571	homotetramer interaction site [polypeptide binding]; other site
1088720001572	carbohydrate binding site [chemical binding]; other site
1088720001573	metal binding site [ion binding]; metal-binding site
1088720001574	WxL domain surface cell wall-binding; Region: WxL; pfam13731
1088720001575	WxL domain surface cell wall-binding; Region: WxL; pfam13731
1088720001576	WxL domain surface cell wall-binding; Region: WxL; pfam13731
1088720001577	legume lectins; Region: lectin_L-type; cd01951
1088720001578	homotetramer interaction site [polypeptide binding]; other site
1088720001579	carbohydrate binding site [chemical binding]; other site
1088720001580	metal binding site [ion binding]; metal-binding site
1088720001581	WxL domain surface cell wall-binding; Region: WxL; pfam13731
1088720001582	EamA-like transporter family; Region: EamA; pfam00892
1088720001583	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1088720001584	EamA-like transporter family; Region: EamA; pfam00892
1088720001585	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
1088720001586	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1088720001587	Walker A/P-loop; other site
1088720001588	ATP binding site [chemical binding]; other site
1088720001589	Q-loop/lid; other site
1088720001590	ABC transporter signature motif; other site
1088720001591	Walker B; other site
1088720001592	D-loop; other site
1088720001593	H-loop/switch region; other site
1088720001594	ECF-type riboflavin transporter, S component; Region: ECF-ribofla_trS; cl17272
1088720001595	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
1088720001596	substrate binding site [chemical binding]; other site
1088720001597	ATP binding site [chemical binding]; other site
1088720001598	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
1088720001599	FAD binding site [chemical binding]; other site
1088720001600	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
1088720001601	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
1088720001602	THF binding site; other site
1088720001603	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1088720001604	substrate binding site [chemical binding]; other site
1088720001605	THF binding site; other site
1088720001606	zinc-binding site [ion binding]; other site
1088720001607	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1088720001608	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1088720001609	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720001610	Walker A/P-loop; other site
1088720001611	ATP binding site [chemical binding]; other site
1088720001612	Q-loop/lid; other site
1088720001613	ABC transporter signature motif; other site
1088720001614	Walker B; other site
1088720001615	D-loop; other site
1088720001616	H-loop/switch region; other site
1088720001617	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1088720001618	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1088720001619	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1088720001620	Walker A/P-loop; other site
1088720001621	ATP binding site [chemical binding]; other site
1088720001622	Q-loop/lid; other site
1088720001623	ABC transporter signature motif; other site
1088720001624	Walker B; other site
1088720001625	D-loop; other site
1088720001626	H-loop/switch region; other site
1088720001627	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
1088720001628	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720001629	putative substrate translocation pore; other site
1088720001630	trehalose operon repressor, B. subtilis-type; Region: trehalos_R_Bsub; TIGR02404
1088720001631	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1088720001632	DNA-binding site [nucleotide binding]; DNA binding site
1088720001633	UTRA domain; Region: UTRA; pfam07702
1088720001634	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
1088720001635	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1088720001636	Ca binding site [ion binding]; other site
1088720001637	active site
1088720001638	catalytic site [active]
1088720001639	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
1088720001640	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
1088720001641	HPr interaction site; other site
1088720001642	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1088720001643	active site
1088720001644	phosphorylation site [posttranslational modification]
1088720001645	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
1088720001646	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1088720001647	active site turn [active]
1088720001648	phosphorylation site [posttranslational modification]
1088720001649	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1088720001650	serine/threonine transporter SstT; Provisional; Region: PRK13628
1088720001651	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1088720001652	amino acid transporter; Region: 2A0306; TIGR00909
1088720001653	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
1088720001654	L-lactate dehydrogenase; Reviewed; Region: ldh; PRK00066
1088720001655	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
1088720001656	NAD binding site [chemical binding]; other site
1088720001657	dimer interface [polypeptide binding]; other site
1088720001658	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1088720001659	substrate binding site [chemical binding]; other site
1088720001660	glutamate dehydrogenase; Provisional; Region: PRK09414
1088720001661	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1088720001662	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
1088720001663	NAD(P) binding site [chemical binding]; other site
1088720001664	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1088720001665	DNA-binding site [nucleotide binding]; DNA binding site
1088720001666	RNA-binding motif; other site
1088720001667	Protein of unknown function (DUF3036); Region: DUF3036; pfam11234
1088720001668	OsmC-like protein; Region: OsmC; pfam02566
1088720001669	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1088720001670	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1088720001671	ABC transporter; Region: ABC_tran_2; pfam12848
1088720001672	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1088720001673	atypical (a) SDRs, subgroup 5; Region: SDR_a5; cd05243
1088720001674	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1088720001675	NAD(P) binding site [chemical binding]; other site
1088720001676	putative active site [active]
1088720001677	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1088720001678	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1088720001679	active site
1088720001680	catalytic tetrad [active]
1088720001681	putative transport protein YifK; Provisional; Region: PRK10746
1088720001682	Protein of unknown function (DUF3800); Region: DUF3800; pfam12686
1088720001683	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
1088720001684	Protein of unknown function (DUF3021); Region: DUF3021; pfam11457
1088720001685	LytTr DNA-binding domain; Region: LytTR; smart00850
1088720001686	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1088720001687	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720001688	Walker A/P-loop; other site
1088720001689	ATP binding site [chemical binding]; other site
1088720001690	Q-loop/lid; other site
1088720001691	ABC transporter signature motif; other site
1088720001692	Walker B; other site
1088720001693	D-loop; other site
1088720001694	H-loop/switch region; other site
1088720001695	Alpha/beta hydrolase of unknown function (DUF915); Region: DUF915; pfam06028
1088720001696	Carbonic anhydrase alpha, prokaryotic-like subfamily. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon...; Region: alpha_CA_prokaryotic_like; cd03124
1088720001697	active site
1088720001698	zinc binding site [ion binding]; other site
1088720001699	hypothetical protein; Provisional; Region: PRK00967
1088720001700	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
1088720001701	nudix motif; other site
1088720001702	alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases; Region: MDR_like_2; cd05289
1088720001703	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
1088720001704	putative NAD(P) binding site [chemical binding]; other site
1088720001705	Ammonia permease [Inorganic ion transport and metabolism]; Region: AmtB; COG0004
1088720001706	Dyp-type peroxidase family; Region: Dyp_perox; cl01067
1088720001707	Uncharacterized membrane protein [Function unknown]; Region: SapB; COG1285
1088720001708	MgtC family; Region: MgtC; pfam02308
1088720001709	DNA/RNA non-specific endonuclease; Region: Endonuclea_NS_2; pfam13930
1088720001710	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
1088720001711	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720001712	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
1088720001713	Walker A/P-loop; other site
1088720001714	ATP binding site [chemical binding]; other site
1088720001715	Q-loop/lid; other site
1088720001716	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1088720001717	ABC transporter; Region: ABC_tran_2; pfam12848
1088720001718	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1088720001719	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720001720	Walker A/P-loop; other site
1088720001721	ATP binding site [chemical binding]; other site
1088720001722	Q-loop/lid; other site
1088720001723	ABC transporter signature motif; other site
1088720001724	Walker B; other site
1088720001725	D-loop; other site
1088720001726	H-loop/switch region; other site
1088720001727	Uncharacterized subfamily of Uracil-DNA glycosylases; Region: UDG_like_1; cd10033
1088720001728	putative uracil binding site [chemical binding]; other site
1088720001729	putative active site [active]
1088720001730	Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism]; Region: GlpF; COG0580
1088720001731	amphipathic channel; other site
1088720001732	Asn-Pro-Ala signature motifs; other site
1088720001733	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GlpA; COG0578
1088720001734	glycerol kinase; Provisional; Region: glpK; PRK00047
1088720001735	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
1088720001736	N- and C-terminal domain interface [polypeptide binding]; other site
1088720001737	active site
1088720001738	MgATP binding site [chemical binding]; other site
1088720001739	catalytic site [active]
1088720001740	metal binding site [ion binding]; metal-binding site
1088720001741	glycerol binding site [chemical binding]; other site
1088720001742	homotetramer interface [polypeptide binding]; other site
1088720001743	homodimer interface [polypeptide binding]; other site
1088720001744	FBP binding site [chemical binding]; other site
1088720001745	protein IIAGlc interface [polypeptide binding]; other site
1088720001746	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1088720001747	active site
1088720001748	CAT RNA binding domain; Region: CAT_RBD; pfam03123
1088720001749	transcriptional antiterminator BglG; Provisional; Region: PRK09772
1088720001750	PRD domain; Region: PRD; pfam00874
1088720001751	PRD domain; Region: PRD; pfam00874
1088720001752	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; cl17295
1088720001753	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
1088720001754	PTS_IIB_lactose: subunit IIB of enzyme II (EII) of the lactose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS) found in Firmicutes as well as Actinobacteria. In this system, EII is a lactose-specific permease with two...; Region: PTS_IIB_lactose; cd05565
1088720001755	active site
1088720001756	P-loop; other site
1088720001757	phosphorylation site [posttranslational modification]
1088720001758	6-phospho-beta-galactosidase; Provisional; Region: PRK13511
1088720001759	beta-galactosidase; Region: BGL; TIGR03356
1088720001760	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cl00166
1088720001761	methionine cluster; other site
1088720001762	active site
1088720001763	phosphorylation site [posttranslational modification]
1088720001764	metal binding site [ion binding]; metal-binding site
1088720001765	galactokinase; Provisional; Region: PRK05322
1088720001766	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
1088720001767	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1088720001768	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1088720001769	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
1088720001770	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1088720001771	NAD binding site [chemical binding]; other site
1088720001772	homodimer interface [polypeptide binding]; other site
1088720001773	active site
1088720001774	substrate binding site [chemical binding]; other site
1088720001775	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK05270
1088720001776	Galactose-1-phosphate uridyl transferase, N-terminal domain; Region: GalP_UDP_transf; pfam01087
1088720001777	Galactose-1-phosphate uridyl transferase, C-terminal domain; Region: GalP_UDP_tr_C; pfam02744
1088720001778	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1088720001779	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1088720001780	DNA binding site [nucleotide binding]
1088720001781	domain linker motif; other site
1088720001782	Ligand-binding domain of DNA transcription repressor GalR which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalR; cd01544
1088720001783	putative dimerization interface [polypeptide binding]; other site
1088720001784	putative ligand binding site [chemical binding]; other site
1088720001785	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
1088720001786	active site
1088720001787	catalytic residues [active]
1088720001788	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1088720001789	active site
1088720001790	phosphorylation site [posttranslational modification]
1088720001791	Phosphotransferase system, galactitol-specific IIB component [Carbohydrate transport and metabolism]; Region: SgaB; COG3414
1088720001792	active site
1088720001793	P-loop; other site
1088720001794	phosphorylation site [posttranslational modification]
1088720001795	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
1088720001796	PTS system sugar-specific permease component; Region: EIIC-GAT; pfam03611
1088720001797	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1088720001798	Beta-lactamase; Region: Beta-lactamase; pfam00144
1088720001799	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1088720001800	tagatose-6-phosphate kinase; Region: lacC; TIGR01231
1088720001801	putative substrate binding site [chemical binding]; other site
1088720001802	putative ATP binding site [chemical binding]; other site
1088720001803	tagatose 1,6-diphosphate aldolase; Reviewed; Region: PRK12399
1088720001804	galactose-6-phosphate isomerase subunit LacB; Reviewed; Region: PRK08622
1088720001805	galactose-6-phosphate isomerase subunit LacA; Reviewed; Region: PRK08621
1088720001806	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1088720001807	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1088720001808	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1088720001809	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
1088720001810	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1088720001811	active site
1088720001812	motif I; other site
1088720001813	motif II; other site
1088720001814	DNA repair exonuclease [DNA replication, recombination, and repair]; Region: SbcD; COG0420
1088720001815	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
1088720001816	active site
1088720001817	metal binding site [ion binding]; metal-binding site
1088720001818	DNA binding site [nucleotide binding]
1088720001819	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
1088720001820	ATP-binding cassette domain of sbcCD; Region: ABC_sbcCD; cd03279
1088720001821	AAA domain; Region: AAA_23; pfam13476
1088720001822	Walker A/P-loop; other site
1088720001823	ATP binding site [chemical binding]; other site
1088720001824	Q-loop/lid; other site
1088720001825	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: SbcC; COG0419
1088720001826	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720001827	ABC transporter signature motif; other site
1088720001828	Walker B; other site
1088720001829	D-loop; other site
1088720001830	H-loop/switch region; other site
1088720001831	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1088720001832	Group of bacterial proteins containing an alpha crystallin domain (ACD) similar to Lactobacillus plantarum (Lp) small heat shock proteins (sHsp) HSP 18.5, HSP 18.55 and HSP 19.3. sHsps are molecular chaperones that suppress protein aggregation and...; Region: ACD_LpsHSP_like; cd06471
1088720001833	putative dimer interface [polypeptide binding]; other site
1088720001834	A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; Region: MutY; COG1194
1088720001835	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1088720001836	minor groove reading motif; other site
1088720001837	helix-hairpin-helix signature motif; other site
1088720001838	substrate binding pocket [chemical binding]; other site
1088720001839	active site
1088720001840	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
1088720001841	DNA binding and oxoG recognition site [nucleotide binding]
1088720001842	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1088720001843	Flavodoxin-like fold; Region: Flavodoxin_2; pfam02525
1088720001844	Short repeat of unknown function (DUF308); Region: DUF308; pfam03729
1088720001845	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
1088720001846	dimer interface [polypeptide binding]; other site
1088720001847	substrate binding site [chemical binding]; other site
1088720001848	ATP binding site [chemical binding]; other site
1088720001849	biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs; Region: BVR-B_like_SDR_a; cd05244
1088720001850	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1088720001851	NAD binding site [chemical binding]; other site
1088720001852	substrate binding site [chemical binding]; other site
1088720001853	putative active site [active]
1088720001854	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1088720001855	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1088720001856	Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915
1088720001857	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1088720001858	Type I periplasmic ligand-binding domain of uncharacterized ABC-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_uncharacterized_transporter; cd06325
1088720001859	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1088720001860	zinc binding site [ion binding]; other site
1088720001861	putative ligand binding site [chemical binding]; other site
1088720001862	Type I periplasmic ligand-binding domain of uncharacterized ABC-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_uncharacterized_transporter; cd06325
1088720001863	zinc binding site [ion binding]; other site
1088720001864	putative ligand binding site [chemical binding]; other site
1088720001865	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1088720001866	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cd06574
1088720001867	TM-ABC transporter signature motif; other site
1088720001868	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: PhnK; COG1101
1088720001869	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720001870	Walker A/P-loop; other site
1088720001871	ATP binding site [chemical binding]; other site
1088720001872	Q-loop/lid; other site
1088720001873	ABC transporter signature motif; other site
1088720001874	Walker B; other site
1088720001875	D-loop; other site
1088720001876	H-loop/switch region; other site
1088720001877	Yhdh and yhfp-like putative quinone oxidoreductases; Region: MDR_yhdh_yhfp; cd05280
1088720001878	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
1088720001879	NADP binding site [chemical binding]; other site
1088720001880	dimer interface [polypeptide binding]; other site
1088720001881	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
1088720001882	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
1088720001883	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1088720001884	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1088720001885	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1088720001886	motif II; other site
1088720001887	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1088720001888	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
1088720001889	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1088720001890	Ligand binding site; other site
1088720001891	Putative Catalytic site; other site
1088720001892	DXD motif; other site
1088720001893	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
1088720001894	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
1088720001895	Predicted membrane protein [Function unknown]; Region: COG2246
1088720001896	GtrA-like protein; Region: GtrA; pfam04138
1088720001897	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1088720001898	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1088720001899	active site
1088720001900	phosphorylation site [posttranslational modification]
1088720001901	intermolecular recognition site; other site
1088720001902	dimerization interface [polypeptide binding]; other site
1088720001903	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1088720001904	DNA binding site [nucleotide binding]
1088720001905	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1088720001906	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1088720001907	dimer interface [polypeptide binding]; other site
1088720001908	phosphorylation site [posttranslational modification]
1088720001909	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1088720001910	ATP binding site [chemical binding]; other site
1088720001911	Mg2+ binding site [ion binding]; other site
1088720001912	G-X-G motif; other site
1088720001913	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4918
1088720001914	Nitroreductase-like family 1. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_1; cd02137
1088720001915	dimer interface [polypeptide binding]; other site
1088720001916	FMN binding site [chemical binding]; other site
1088720001917	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1088720001918	FMN-dependent dehydrogenase; Region: FMN_dh; pfam01070
1088720001919	phosphate binding site [ion binding]; other site
1088720001920	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
1088720001921	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1088720001922	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1088720001923	non-specific DNA binding site [nucleotide binding]; other site
1088720001924	salt bridge; other site
1088720001925	sequence-specific DNA binding site [nucleotide binding]; other site
1088720001926	Helix-turn-helix domain; Region: HTH_19; pfam12844
1088720001927	Predicted transcriptional regulators [Transcription]; Region: COG1695
1088720001928	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1088720001929	Sugar efflux transporter for intercellular exchange; Region: MtN3_slv; pfam03083
1088720001930	zinc-binding alcohol dehydrogenase family protein; Region: adh_fam_1; TIGR02817
1088720001931	Arginate lyase and other MDR family members; Region: AL_MDR; cd08252
1088720001932	putative NAD(P) binding site [chemical binding]; other site
1088720001933	dimer interface [polypeptide binding]; other site
1088720001934	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1088720001935	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1088720001936	LexA repressor; Validated; Region: PRK00215
1088720001937	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
1088720001938	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1088720001939	Catalytic site [active]
1088720001940	Membrane transport protein; Region: Mem_trans; pfam03547
1088720001941	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
1088720001942	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
1088720001943	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
1088720001944	Uncharacterized conserved protein [Function unknown]; Region: COG3189
1088720001945	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
1088720001946	uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u2; cd12827
1088720001947	Cl binding site [ion binding]; other site
1088720001948	oligomer interface [polypeptide binding]; other site
1088720001949	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1088720001950	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1088720001951	The substrate binding domain of LysR-type transcriptional regulator MleR which required for malolactic fermentation, contains type 2 periplasmic binidning fold; Region: PBP2_MleR; cd08437
1088720001952	putative dimerization interface [polypeptide binding]; other site
1088720001953	malate dehydrogenase; Provisional; Region: PRK13529
1088720001954	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1088720001955	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
1088720001956	NAD(P) binding site [chemical binding]; other site
1088720001957	Membrane transport protein; Region: Mem_trans; cl09117
1088720001958	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
1088720001959	dimer interface [polypeptide binding]; other site
1088720001960	catalytic triad [active]
1088720001961	peroxidatic and resolving cysteines [active]
1088720001962	Flavodoxin domain; Region: Flavodoxin_5; cl17428
1088720001963	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1088720001964	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1088720001965	non-specific DNA binding site [nucleotide binding]; other site
1088720001966	salt bridge; other site
1088720001967	sequence-specific DNA binding site [nucleotide binding]; other site
1088720001968	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
1088720001969	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1088720001970	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1088720001971	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1088720001972	Walker A/P-loop; other site
1088720001973	ATP binding site [chemical binding]; other site
1088720001974	Q-loop/lid; other site
1088720001975	ABC transporter signature motif; other site
1088720001976	Walker B; other site
1088720001977	D-loop; other site
1088720001978	H-loop/switch region; other site
1088720001979	oligoendopeptidase F; Region: pepF; TIGR00181
1088720001980	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_4; cd09609
1088720001981	active site
1088720001982	Zn binding site [ion binding]; other site
1088720001983	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
1088720001984	active site
1088720001985	multimer interface [polypeptide binding]; other site
1088720001986	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1088720001987	ATPase, P-type (transporting), HAD superfamily, subfamily IC; Region: ATPase_P-type; TIGR01494
1088720001988	proline-specific peptidase, Bacillus coagulans-type subfamily; Region: pro_imino_pep_2; TIGR01250
1088720001989	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
1088720001990	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
1088720001991	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
1088720001992	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1088720001993	motif II; other site
1088720001994	HAD-hyrolase-like; Region: Hydrolase_like; pfam13242
1088720001995	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1088720001996	MarR family; Region: MarR_2; pfam12802
1088720001997	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1088720001998	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
1088720001999	flavoprotein NrdI; Provisional; Region: PRK02551
1088720002000	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1088720002001	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1088720002002	active site
1088720002003	catalytic tetrad [active]
1088720002004	Alpha/beta hydrolase of unknown function (DUF915); Region: DUF915; pfam06028
1088720002005	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1088720002006	Predicted membrane protein [Function unknown]; Region: COG2323
1088720002007	Protein of unknown function (DUF3290); Region: DUF3290; pfam11694
1088720002008	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1088720002009	substrate binding site [chemical binding]; other site
1088720002010	zinc-binding site [ion binding]; other site
1088720002011	S-ribosylhomocysteinase; Provisional; Region: PRK02260
1088720002012	Uncharacterized conserved protein [Function unknown]; Region: COG0398
1088720002013	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1088720002014	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
1088720002015	RuvA N terminal domain; Region: RuvA_N; pfam01330
1088720002016	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
1088720002017	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1088720002018	Walker A motif; other site
1088720002019	ATP binding site [chemical binding]; other site
1088720002020	Walker B motif; other site
1088720002021	arginine finger; other site
1088720002022	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1088720002023	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
1088720002024	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1088720002025	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1088720002026	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
1088720002027	Preprotein translocase subunit; Region: YajC; pfam02699
1088720002028	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
1088720002029	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
1088720002030	putative catalytic cysteine [active]
1088720002031	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
1088720002032	putative active site [active]
1088720002033	metal binding site [ion binding]; metal-binding site
1088720002034	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
1088720002035	Helix-turn-helix diphteria tox regulatory element; Region: HTH_DTXR; smart00529
1088720002036	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
1088720002037	FeoA domain; Region: FeoA; pfam04023
1088720002038	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
1088720002039	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
1088720002040	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
1088720002041	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
1088720002042	active site
1088720002043	DNA polymerase IV; Validated; Region: PRK02406
1088720002044	DNA binding site [nucleotide binding]
1088720002045	Predicted transcriptional regulator containing CBS domains [Transcription]; Region: COG4109
1088720002046	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1088720002047	DNA-binding site [nucleotide binding]; DNA binding site
1088720002048	DRTGG domain; Region: DRTGG; pfam07085
1088720002049	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
1088720002050	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
1088720002051	DHH family; Region: DHH; pfam01368
1088720002052	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
1088720002053	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1088720002054	ATP binding site [chemical binding]; other site
1088720002055	Mg++ binding site [ion binding]; other site
1088720002056	motif III; other site
1088720002057	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1088720002058	nucleotide binding region [chemical binding]; other site
1088720002059	ATP-binding site [chemical binding]; other site
1088720002060	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1088720002061	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1088720002062	motif 1; other site
1088720002063	active site
1088720002064	motif 2; other site
1088720002065	motif 3; other site
1088720002066	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1088720002067	hypothetical protein; Provisional; Region: PRK05473
1088720002068	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
1088720002069	hypothetical protein; Provisional; Region: PRK13678
1088720002070	Cell division protein ZapA; Region: ZapA; pfam05164
1088720002071	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
1088720002072	Colicin V production protein; Region: Colicin_V; pfam02674
1088720002073	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
1088720002074	MutS domain III; Region: MutS_III; pfam05192
1088720002075	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720002076	Walker A/P-loop; other site
1088720002077	ATP binding site [chemical binding]; other site
1088720002078	Q-loop/lid; other site
1088720002079	ABC transporter signature motif; other site
1088720002080	Walker B; other site
1088720002081	D-loop; other site
1088720002082	H-loop/switch region; other site
1088720002083	Smr domain; Region: Smr; pfam01713
1088720002084	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1088720002085	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1088720002086	catalytic residues [active]
1088720002087	D-Ala-teichoic acid biosynthesis protein; Region: DUF3687; pfam12459
1088720002088	D-alanine--poly(phosphoribitol) ligase, subunit 1; Region: D-ala-DACP-lig; TIGR01734
1088720002089	D-alanine:D-alanyl carrier protein ligase (DltA); Region: DltA; cd05945
1088720002090	acyl-activating enzyme (AAE) consensus motif; other site
1088720002091	AMP binding site [chemical binding]; other site
1088720002092	D-alanyl-lipoteichoic acid biosynthesis protein DltB; Region: LTA_dltB; TIGR04091
1088720002093	D-alanine--poly(phosphoribitol) ligase subunit 2; Validated; Region: PRK05087
1088720002094	D-alanyl-lipoteichoic acid biosynthesis protein DltD; Region: LTA_DltD; TIGR04092
1088720002095	DltD N-terminal region; Region: DltD_N; pfam04915
1088720002096	DltD central region; Region: DltD_M; pfam04918
1088720002097	DltD C-terminal region; Region: DltD_C; pfam04914
1088720002098	Protein of unknown function (DUF2507); Region: DUF2507; pfam10702
1088720002099	glutamate racemase; Provisional; Region: PRK00865
1088720002100	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
1088720002101	active site
1088720002102	dimerization interface [polypeptide binding]; other site
1088720002103	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
1088720002104	active site
1088720002105	metal binding site [ion binding]; metal-binding site
1088720002106	homotetramer interface [polypeptide binding]; other site
1088720002107	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_30; cd04643
1088720002108	FOG: CBS domain [General function prediction only]; Region: COG0517
1088720002109	Domain of unknown function (DUF368); Region: DUF368; pfam04018
1088720002110	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1088720002111	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1088720002112	Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain [General function prediction only]; Region: COG4768
1088720002113	YtxH-like protein; Region: YtxH; pfam12732
1088720002114	Predicted small molecule binding protein (contains 3H domain) [General function prediction only]; Region: COG1827
1088720002115	HTH domain; Region: HTH_11; pfam08279
1088720002116	3H domain; Region: 3H; pfam02829
1088720002117	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
1088720002118	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1088720002119	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
1088720002120	active site
1088720002121	catabolite control protein A; Region: ccpA; TIGR01481
1088720002122	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1088720002123	DNA binding site [nucleotide binding]
1088720002124	domain linker motif; other site
1088720002125	Ligand-binding domain of the catabolite control protein A (CcpA), which functions as the major transcriptional regulator of carbon catabolite repression/regulation; Region: PBP1_CcpA_like; cd06298
1088720002126	dimerization interface [polypeptide binding]; other site
1088720002127	effector binding site; other site
1088720002128	Transglycosylase; Region: Transgly; pfam00912
1088720002129	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
1088720002130	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1088720002131	HAD superfamily (subfamily IA) hydrolase, TIGR02254; Region: YjjG/YfnB
1088720002132	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1088720002133	motif II; other site
1088720002134	birA, biotin-[acetyl-CoA-carboxylase] ligase region; Region: birA_ligase; TIGR00121
1088720002135	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
1088720002136	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
1088720002137	dipeptidase PepV; Reviewed; Region: PRK07318
1088720002138	M20 Peptidase Xaa-His dipeptidase (PepV) degrades hydrophobic dipeptides; Region: M20_PepV; cd03888
1088720002139	active site
1088720002140	metal binding site [ion binding]; metal-binding site
1088720002141	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
1088720002142	Glycerophosphodiester phosphodiesterase domain as found in prokaryota and eukaryota, and similar proteins; Region: GDPD; cd08556
1088720002143	active site
1088720002144	catalytic site [active]
1088720002145	metal binding site [ion binding]; metal-binding site
1088720002146	YibE/F-like protein; Region: YibE_F; pfam07907
1088720002147	YibE/F-like protein; Region: YibE_F; cl02259
1088720002148	Aquifex aeolicus AQ1575 and related proteins, metallophosphatase domain; Region: MPP_AQ1575; cd07390
1088720002149	putative active site [active]
1088720002150	putative metal binding site [ion binding]; other site
1088720002151	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
1088720002152	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1088720002153	active site
1088720002154	metal binding site [ion binding]; metal-binding site
1088720002155	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1088720002156	Protein of unknown function (DUF1027); Region: DUF1027; pfam06265
1088720002157	HAD-superfamily subfamily IIA hydrolase, TIGR01457; Region: HAD-SF-IIA-hyp2
1088720002158	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1088720002159	active site
1088720002160	motif I; other site
1088720002161	motif II; other site
1088720002162	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1088720002163	Protein of unknown function (DUF1461); Region: DUF1461; pfam07314
1088720002164	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1088720002165	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1088720002166	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
1088720002167	tetramer interfaces [polypeptide binding]; other site
1088720002168	binuclear metal-binding site [ion binding]; other site
1088720002169	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
1088720002170	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1088720002171	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1088720002172	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cl00197
1088720002173	active site
1088720002174	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cd00164
1088720002175	RNA binding site [nucleotide binding]; other site
1088720002176	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1088720002177	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1088720002178	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1088720002179	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1088720002180	This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1; Region: GT1_UGDG_like; cd03817
1088720002181	putative ADP-binding pocket [chemical binding]; other site
1088720002182	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1088720002183	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1088720002184	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
1088720002185	aromatic amino acid aminotransferase; Validated; Region: PRK07309
1088720002186	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1088720002187	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1088720002188	homodimer interface [polypeptide binding]; other site
1088720002189	catalytic residue [active]
1088720002190	Protein of unknown function (DUF1797); Region: DUF1797; pfam08796
1088720002191	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
1088720002192	Sulfatase; Region: Sulfatase; pfam00884
1088720002193	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1088720002194	metal binding site 2 [ion binding]; metal-binding site
1088720002195	putative DNA binding helix; other site
1088720002196	metal binding site 1 [ion binding]; metal-binding site
1088720002197	dimer interface [polypeptide binding]; other site
1088720002198	structural Zn2+ binding site [ion binding]; other site
1088720002199	S-adenosylmethionine synthetase; Validated; Region: PRK05250
1088720002200	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
1088720002201	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
1088720002202	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
1088720002203	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720002204	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1088720002205	putative substrate translocation pore; other site
1088720002206	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720002207	Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators; Region: HTH_GlnR-like; cd01105
1088720002208	DNA binding residues [nucleotide binding]
1088720002209	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1088720002210	putative dimer interface [polypeptide binding]; other site
1088720002211	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1088720002212	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720002213	putative substrate translocation pore; other site
1088720002214	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720002215	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
1088720002216	active site
1088720002217	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
1088720002218	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1088720002219	HIGH motif; other site
1088720002220	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1088720002221	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1088720002222	active site
1088720002223	KMSKS motif; other site
1088720002224	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
1088720002225	tRNA binding surface [nucleotide binding]; other site
1088720002226	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1088720002227	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
1088720002228	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
1088720002229	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1088720002230	RNA binding surface [nucleotide binding]; other site
1088720002231	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
1088720002232	active site
1088720002233	uracil binding [chemical binding]; other site
1088720002234	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082); Region: DUF2082; pfam09855
1088720002235	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
1088720002236	putative substrate binding site [chemical binding]; other site
1088720002237	putative ATP binding site [chemical binding]; other site
1088720002238	Contains a crystal structure of the Nudix hydrolase from Enterococcus faecalis, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_25; cd04684
1088720002239	nudix motif; other site
1088720002240	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
1088720002241	catalytic residues [active]
1088720002242	dimer interface [polypeptide binding]; other site
1088720002243	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
1088720002244	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1088720002245	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1088720002246	homodimer interface [polypeptide binding]; other site
1088720002247	catalytic residue [active]
1088720002248	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1088720002249	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
1088720002250	active site
1088720002251	metal binding site [ion binding]; metal-binding site
1088720002252	ACT domain proteins similar to the yet uncharacterized Streptococcus pneumoniae ACT domain protein; Region: ACT_1ZPV; cd04872
1088720002253	Uncharacterized proteins with similarity to Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL_like_DUF711; cd08025
1088720002254	Competence protein CoiA-like family; Region: CoiA; cl11541
1088720002255	Thioredoxin; Region: Thioredoxin_5; pfam13743
1088720002256	Uncharacterized subgroup 1 of the CYTH-like superfamily; Region: CYTH-like_Pase_1; cd07762
1088720002257	putative active site [active]
1088720002258	putative metal binding residues [ion binding]; other site
1088720002259	signature motif; other site
1088720002260	putative triphosphate binding site [ion binding]; other site
1088720002261	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1088720002262	synthetase active site [active]
1088720002263	NTP binding site [chemical binding]; other site
1088720002264	metal binding site [ion binding]; metal-binding site
1088720002265	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK04885
1088720002266	ATP-NAD kinase; Region: NAD_kinase; pfam01513
1088720002267	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1088720002268	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1088720002269	RNA binding surface [nucleotide binding]; other site
1088720002270	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1088720002271	active site
1088720002272	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
1088720002273	ApbE family; Region: ApbE; pfam02424
1088720002274	Uncharacterized protein involved in copper resistance [Inorganic ion transport and metabolism]; Region: CutC; COG3142
1088720002275	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
1088720002276	Lactonase, 7-bladed beta-propeller; Region: Lactonase; pfam10282
1088720002277	PTS system glucitol/sorbitol-specific IIA component; Region: PTSIIA_gutA; cl01516
1088720002278	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
1088720002279	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05458
1088720002280	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1088720002281	active site
1088720002282	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1088720002283	uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u2; cd12827
1088720002284	Cl binding site [ion binding]; other site
1088720002285	oligomer interface [polypeptide binding]; other site
1088720002286	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
1088720002287	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1088720002288	S-adenosylmethionine binding site [chemical binding]; other site
1088720002289	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
1088720002290	Protein of unknown function (DUF1149); Region: DUF1149; pfam06619
1088720002291	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1088720002292	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1088720002293	This domain directs oriented DNA translocation and forms a winged helix structure; Region: Ftsk_gamma; smart00843
1088720002294	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1088720002295	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1088720002296	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1088720002297	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1088720002298	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1088720002299	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
1088720002300	classical (c) SDRs; Region: SDR_c; cd05233
1088720002301	NAD(P) binding site [chemical binding]; other site
1088720002302	active site
1088720002303	Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown]; Region: COG1426
1088720002304	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1088720002305	non-specific DNA binding site [nucleotide binding]; other site
1088720002306	salt bridge; other site
1088720002307	sequence-specific DNA binding site [nucleotide binding]; other site
1088720002308	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
1088720002309	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
1088720002310	competence damage-inducible protein A; Provisional; Region: PRK00549
1088720002311	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
1088720002312	putative MPT binding site; other site
1088720002313	Uncharacterized protein (competence- and mitomycin-induced) [General function prediction only]; Region: CinA; COG1546
1088720002314	recombinase A; Provisional; Region: recA; PRK09354
1088720002315	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1088720002316	hexamer interface [polypeptide binding]; other site
1088720002317	Walker A motif; other site
1088720002318	ATP binding site [chemical binding]; other site
1088720002319	Walker B motif; other site
1088720002320	ribonuclease Y; Region: RNase_Y; TIGR03319
1088720002321	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1088720002322	Zn2+ binding site [ion binding]; other site
1088720002323	Mg2+ binding site [ion binding]; other site
1088720002324	Uncharacterized conserved protein [Function unknown]; Region: COG1739
1088720002325	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
1088720002326	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
1088720002327	Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein) [DNA replication, recombination, and repair]; Region: comFA; COG4098
1088720002328	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1088720002329	ATP binding site [chemical binding]; other site
1088720002330	putative Mg++ binding site [ion binding]; other site
1088720002331	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1088720002332	nucleotide binding region [chemical binding]; other site
1088720002333	ATP-binding site [chemical binding]; other site
1088720002334	comF family protein; Region: comF; TIGR00201
1088720002335	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1088720002336	30S subunit binding site; other site
1088720002337	preprotein translocase subunit SecA; Reviewed; Region: secA; PRK12906
1088720002338	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1088720002339	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1088720002340	nucleotide binding region [chemical binding]; other site
1088720002341	ATP-binding site [chemical binding]; other site
1088720002342	peptide chain release factor 2; Provisional; Region: PRK05589
1088720002343	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1088720002344	RF-1 domain; Region: RF-1; pfam00472
1088720002345	Predicted ATPase involved in cell division [Cell division and chromosome partitioning]; Region: FtsE; COG2884
1088720002346	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720002347	Walker A/P-loop; other site
1088720002348	ATP binding site [chemical binding]; other site
1088720002349	Q-loop/lid; other site
1088720002350	ABC transporter signature motif; other site
1088720002351	Walker B; other site
1088720002352	D-loop; other site
1088720002353	H-loop/switch region; other site
1088720002354	Cell division protein [Cell division and chromosome partitioning]; Region: FtsX; COG2177
1088720002355	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
1088720002356	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1088720002357	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1088720002358	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1088720002359	active site
1088720002360	phosphorylation site [posttranslational modification]
1088720002361	intermolecular recognition site; other site
1088720002362	dimerization interface [polypeptide binding]; other site
1088720002363	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1088720002364	DNA binding site [nucleotide binding]
1088720002365	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: VicK; COG5002
1088720002366	PAS domain; Region: PAS_8; pfam13188
1088720002367	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1088720002368	dimer interface [polypeptide binding]; other site
1088720002369	phosphorylation site [posttranslational modification]
1088720002370	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1088720002371	ATP binding site [chemical binding]; other site
1088720002372	Mg2+ binding site [ion binding]; other site
1088720002373	G-X-G motif; other site
1088720002374	PBP superfamily domain; Region: PBP_like_2; cl17296
1088720002375	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1088720002376	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573
1088720002377	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1088720002378	dimer interface [polypeptide binding]; other site
1088720002379	conserved gate region; other site
1088720002380	putative PBP binding loops; other site
1088720002381	ABC-ATPase subunit interface; other site
1088720002382	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstA; COG0581
1088720002383	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1088720002384	dimer interface [polypeptide binding]; other site
1088720002385	conserved gate region; other site
1088720002386	putative PBP binding loops; other site
1088720002387	ABC-ATPase subunit interface; other site
1088720002388	phosphate transporter ATP-binding protein; Provisional; Region: PRK14237
1088720002389	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1088720002390	Walker A/P-loop; other site
1088720002391	ATP binding site [chemical binding]; other site
1088720002392	Q-loop/lid; other site
1088720002393	ABC transporter signature motif; other site
1088720002394	Walker B; other site
1088720002395	D-loop; other site
1088720002396	H-loop/switch region; other site
1088720002397	phosphate ABC transporter ATP-binding protein; Provisional; Region: PRK14255
1088720002398	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1088720002399	Walker A/P-loop; other site
1088720002400	ATP binding site [chemical binding]; other site
1088720002401	Q-loop/lid; other site
1088720002402	ABC transporter signature motif; other site
1088720002403	Walker B; other site
1088720002404	D-loop; other site
1088720002405	H-loop/switch region; other site
1088720002406	phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135
1088720002407	PhoU domain; Region: PhoU; pfam01895
1088720002408	PhoU domain; Region: PhoU; pfam01895
1088720002409	Uncharacterized conserved protein [Function unknown]; Region: COG3595
1088720002410	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
1088720002411	Membrane protein of unknown function; Region: DUF360; pfam04020
1088720002412	HPr kinase/phosphorylase; Provisional; Region: PRK05428
1088720002413	HPr Serine kinase N terminus; Region: Hpr_kinase_N; pfam02603
1088720002414	HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent...; Region: HprK_C; cd01918
1088720002415	Hpr binding site; other site
1088720002416	active site
1088720002417	homohexamer subunit interaction site [polypeptide binding]; other site
1088720002418	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK12437
1088720002419	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
1088720002420	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1088720002421	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1088720002422	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
1088720002423	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1088720002424	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1088720002425	phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150
1088720002426	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
1088720002427	active site
1088720002428	substrate binding site [chemical binding]; other site
1088720002429	metal binding site [ion binding]; metal-binding site
1088720002430	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1088720002431	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1088720002432	active site
1088720002433	phosphorylation site [posttranslational modification]
1088720002434	intermolecular recognition site; other site
1088720002435	dimerization interface [polypeptide binding]; other site
1088720002436	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1088720002437	DNA binding site [nucleotide binding]
1088720002438	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1088720002439	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
1088720002440	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1088720002441	Mg2+ binding site [ion binding]; other site
1088720002442	G-X-G motif; other site
1088720002443	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1088720002444	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1088720002445	Walker A/P-loop; other site
1088720002446	ATP binding site [chemical binding]; other site
1088720002447	Q-loop/lid; other site
1088720002448	ABC transporter signature motif; other site
1088720002449	Walker B; other site
1088720002450	D-loop; other site
1088720002451	H-loop/switch region; other site
1088720002452	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1088720002453	Zn2+ binding site [ion binding]; other site
1088720002454	Mg2+ binding site [ion binding]; other site
1088720002455	excinuclease ABC subunit B; Provisional; Region: PRK05298
1088720002456	Myosin and Kinesin motor domain. These ATPases belong to the P-loop NTPase family and provide the driving force in myosin and kinesin mediated processes; Region: Motor_domain; cl00286
1088720002457	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1088720002458	ATP-binding site [chemical binding]; other site
1088720002459	ATP binding site [chemical binding]; other site
1088720002460	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1088720002461	nucleotide binding region [chemical binding]; other site
1088720002462	ATP-binding site [chemical binding]; other site
1088720002463	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1088720002464	UvrB/uvrC motif; Region: UVR; pfam02151
1088720002465	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1088720002466	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1088720002467	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1088720002468	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1088720002469	Short repeat of unknown function (DUF308); Region: DUF308; cl15828
1088720002470	glmZ(sRNA)-inactivating NTPase; Provisional; Region: PRK05416
1088720002471	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
1088720002472	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
1088720002473	phosphate binding site [ion binding]; other site
1088720002474	putative substrate binding pocket [chemical binding]; other site
1088720002475	dimer interface [polypeptide binding]; other site
1088720002476	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1481
1088720002477	Sporulation Regulator WhiA N terminal; Region: WhiA_N; pfam10298
1088720002478	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1088720002479	MarR family; Region: MarR; pfam01047
1088720002480	Clp protease; Region: CLP_protease; pfam00574
1088720002481	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1088720002482	oligomer interface [polypeptide binding]; other site
1088720002483	active site residues [active]
1088720002484	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
1088720002485	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1088720002486	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
1088720002487	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1088720002488	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
1088720002489	Phosphoglycerate kinase; Region: PGK; pfam00162
1088720002490	substrate binding site [chemical binding]; other site
1088720002491	hinge regions; other site
1088720002492	ADP binding site [chemical binding]; other site
1088720002493	catalytic site [active]
1088720002494	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1088720002495	triosephosphate isomerase; Provisional; Region: PRK14567
1088720002496	substrate binding site [chemical binding]; other site
1088720002497	dimer interface [polypeptide binding]; other site
1088720002498	catalytic triad [active]
1088720002499	enolase; Provisional; Region: eno; PRK00077
1088720002500	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
1088720002501	dimer interface [polypeptide binding]; other site
1088720002502	metal binding site [ion binding]; metal-binding site
1088720002503	substrate binding pocket [chemical binding]; other site
1088720002504	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
1088720002505	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1088720002506	Cl- selectivity filter; other site
1088720002507	Cl- binding residues [ion binding]; other site
1088720002508	pore gating glutamate residue; other site
1088720002509	dimer interface [polypeptide binding]; other site
1088720002510	H+/Cl- coupling transport residue; other site
1088720002511	TrkA-C domain; Region: TrkA_C; pfam02080
1088720002512	preprotein translocase subunit SecG; Reviewed; Region: secG; PRK06870
1088720002513	Esterase/lipase [General function prediction only]; Region: COG1647
1088720002514	ribonuclease R; Region: RNase_R; TIGR02063
1088720002515	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1088720002516	RNB domain; Region: RNB; pfam00773
1088720002517	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
1088720002518	RNA binding site [nucleotide binding]; other site
1088720002519	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1088720002520	SmpB-tmRNA interface; other site
1088720002521	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
1088720002522	homodimer interface [polypeptide binding]; other site
1088720002523	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
1088720002524	active site
1088720002525	homodimer interface [polypeptide binding]; other site
1088720002526	catalytic site [active]
1088720002527	maltose phosphorylase; Provisional; Region: PRK13807
1088720002528	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
1088720002529	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
1088720002530	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
1088720002531	beta-phosphoglucomutase; Region: bPGM; TIGR01990
1088720002532	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1088720002533	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1088720002534	motif II; other site
1088720002535	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1088720002536	sequence-specific DNA binding site [nucleotide binding]; other site
1088720002537	salt bridge; other site
1088720002538	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
1088720002539	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1088720002540	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
1088720002541	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1088720002542	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1088720002543	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1088720002544	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1088720002545	dimer interface [polypeptide binding]; other site
1088720002546	conserved gate region; other site
1088720002547	putative PBP binding loops; other site
1088720002548	ABC-ATPase subunit interface; other site
1088720002549	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1088720002550	dimer interface [polypeptide binding]; other site
1088720002551	conserved gate region; other site
1088720002552	putative PBP binding loops; other site
1088720002553	ABC-ATPase subunit interface; other site
1088720002554	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720002555	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
1088720002556	Walker A/P-loop; other site
1088720002557	ATP binding site [chemical binding]; other site
1088720002558	Q-loop/lid; other site
1088720002559	ABC transporter signature motif; other site
1088720002560	Walker B; other site
1088720002561	D-loop; other site
1088720002562	H-loop/switch region; other site
1088720002563	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1088720002564	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1088720002565	Coenzyme A binding pocket [chemical binding]; other site
1088720002566	Tubby C 2; Region: Tub_2; cl02043
1088720002567	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1088720002568	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1088720002569	active site
1088720002570	motif I; other site
1088720002571	motif II; other site
1088720002572	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
1088720002573	ligand binding site [chemical binding]; other site
1088720002574	active site
1088720002575	UGI interface [polypeptide binding]; other site
1088720002576	catalytic site [active]
1088720002577	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
1088720002578	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
1088720002579	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4152
1088720002580	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720002581	Walker A/P-loop; other site
1088720002582	ATP binding site [chemical binding]; other site
1088720002583	Q-loop/lid; other site
1088720002584	ABC transporter signature motif; other site
1088720002585	Walker B; other site
1088720002586	D-loop; other site
1088720002587	H-loop/switch region; other site
1088720002588	Domain of unknown function (DUF4162); Region: DUF4162; pfam13732
1088720002589	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
1088720002590	an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III; Region: DNA_pol_III_epsilon_like; cd06130
1088720002591	active site
1088720002592	catalytic site [active]
1088720002593	substrate binding site [chemical binding]; other site
1088720002594	Human Ape1-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Ape1-like_AP-endo; cd09087
1088720002595	active site
1088720002596	putative catalytic site [active]
1088720002597	DNA binding site [nucleotide binding]
1088720002598	putative phosphate binding site [ion binding]; other site
1088720002599	metal binding site A [ion binding]; metal-binding site
1088720002600	AP binding site [nucleotide binding]; other site
1088720002601	metal binding site B [ion binding]; metal-binding site
1088720002602	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
1088720002603	FAD binding domain; Region: FAD_binding_4; pfam01565
1088720002604	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1088720002605	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
1088720002606	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1088720002607	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1088720002608	non-specific DNA binding site [nucleotide binding]; other site
1088720002609	salt bridge; other site
1088720002610	sequence-specific DNA binding site [nucleotide binding]; other site
1088720002611	Cupin domain; Region: Cupin_2; pfam07883
1088720002612	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
1088720002613	ATP-binding cassette domain of the polyamine transporter; Region: ABC_PotA_N; cd03300
1088720002614	Walker A/P-loop; other site
1088720002615	ATP binding site [chemical binding]; other site
1088720002616	Q-loop/lid; other site
1088720002617	ABC transporter signature motif; other site
1088720002618	Walker B; other site
1088720002619	D-loop; other site
1088720002620	H-loop/switch region; other site
1088720002621	TOBE domain; Region: TOBE_2; pfam08402
1088720002622	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1088720002623	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1088720002624	dimer interface [polypeptide binding]; other site
1088720002625	conserved gate region; other site
1088720002626	putative PBP binding loops; other site
1088720002627	ABC-ATPase subunit interface; other site
1088720002628	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1088720002629	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1088720002630	dimer interface [polypeptide binding]; other site
1088720002631	conserved gate region; other site
1088720002632	putative PBP binding loops; other site
1088720002633	ABC-ATPase subunit interface; other site
1088720002634	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
1088720002635	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1088720002636	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
1088720002637	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
1088720002638	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1088720002639	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1088720002640	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1088720002641	motif II; other site
1088720002642	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1088720002643	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1088720002644	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1088720002645	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
1088720002646	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1088720002647	ABC-2 type transporter; Region: ABC2_membrane; cl17235
1088720002648	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1088720002649	ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system; Region: PQQ_ABC_ATP; TIGR03864
1088720002650	Walker A/P-loop; other site
1088720002651	ATP binding site [chemical binding]; other site
1088720002652	Q-loop/lid; other site
1088720002653	ABC transporter signature motif; other site
1088720002654	Walker B; other site
1088720002655	D-loop; other site
1088720002656	H-loop/switch region; other site
1088720002657	Uncharacterized conserved protein [Function unknown]; Region: COG1624
1088720002658	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
1088720002659	YbbR-like protein; Region: YbbR; pfam07949
1088720002660	YbbR-like protein; Region: YbbR; pfam07949
1088720002661	YbbR-like protein; Region: YbbR; pfam07949
1088720002662	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14316
1088720002663	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
1088720002664	active site
1088720002665	substrate binding site [chemical binding]; other site
1088720002666	metal binding site [ion binding]; metal-binding site
1088720002667	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
1088720002668	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
1088720002669	glutaminase active site [active]
1088720002670	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1088720002671	dimer interface [polypeptide binding]; other site
1088720002672	active site
1088720002673	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1088720002674	dimer interface [polypeptide binding]; other site
1088720002675	active site
1088720002676	oligoendopeptidase, pepF/M3 family; Region: M3_fam_3; TIGR02290
1088720002677	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_2; cd09607
1088720002678	active site
1088720002679	Zn binding site [ion binding]; other site
1088720002680	Predicted integral membrane protein [Function unknown]; Region: COG5652
1088720002681	hypothetical protein; Validated; Region: PRK00110
1088720002682	Type II/IV secretion system protein; Region: T2SE; pfam00437
1088720002683	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1088720002684	Walker A motif; other site
1088720002685	ATP binding site [chemical binding]; other site
1088720002686	Walker B motif; other site
1088720002687	Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459
1088720002688	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1088720002689	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
1088720002690	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827
1088720002691	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1088720002692	S-adenosylmethionine binding site [chemical binding]; other site
1088720002693	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
1088720002694	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1088720002695	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cl17185
1088720002696	putative acyl-acceptor binding pocket; other site
1088720002697	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1088720002698	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
1088720002699	active site
1088720002700	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
1088720002701	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
1088720002702	Ligand binding site; other site
1088720002703	metal-binding site
1088720002704	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1088720002705	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1088720002706	putative acyl-acceptor binding pocket; other site
1088720002707	Alpha-galactosidase [Carbohydrate transport and metabolism]; Region: GalA; COG3345
1088720002708	Melibiase; Region: Melibiase; pfam02065
1088720002709	SdpI/YhfL protein family; Region: SdpI; pfam13630
1088720002710	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1088720002711	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1088720002712	active site
1088720002713	phosphorylation site [posttranslational modification]
1088720002714	intermolecular recognition site; other site
1088720002715	dimerization interface [polypeptide binding]; other site
1088720002716	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1088720002717	DNA binding site [nucleotide binding]
1088720002718	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1088720002719	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1088720002720	dimerization interface [polypeptide binding]; other site
1088720002721	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1088720002722	dimer interface [polypeptide binding]; other site
1088720002723	phosphorylation site [posttranslational modification]
1088720002724	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1088720002725	ATP binding site [chemical binding]; other site
1088720002726	Mg2+ binding site [ion binding]; other site
1088720002727	G-X-G motif; other site
1088720002728	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1088720002729	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1088720002730	Coenzyme A binding pocket [chemical binding]; other site
1088720002731	hypothetical protein; Provisional; Region: PRK04435
1088720002732	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cl17393
1088720002733	DNA-binding interface [nucleotide binding]; DNA binding site
1088720002734	C-terminal ACT domain of a small (; 147 a.a.) putative phenylalanine biosynthetic pathway protein described in Bacillus subtilis (BS) PheB (PheB-BS) and related domains; Region: ACT_PheB-BS; cd04888
1088720002735	DNA polymerase IV; Reviewed; Region: PRK03103
1088720002736	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
1088720002737	active site
1088720002738	DNA binding site [nucleotide binding]
1088720002739	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1088720002740	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
1088720002741	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
1088720002742	active site
1088720002743	catalytic triad [active]
1088720002744	oxyanion hole [active]
1088720002745	Bacterial protein of unknown function (DUF898); Region: DUF898; cl01738
1088720002746	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
1088720002747	Part of AAA domain; Region: AAA_19; pfam13245
1088720002748	Family description; Region: UvrD_C_2; pfam13538
1088720002749	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
1088720002750	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
1088720002751	nucleotide binding pocket [chemical binding]; other site
1088720002752	K-X-D-G motif; other site
1088720002753	catalytic site [active]
1088720002754	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1088720002755	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
1088720002756	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1088720002757	Dimer interface [polypeptide binding]; other site
1088720002758	BRCT sequence motif; other site
1088720002759	N-terminal repeat domain of CamS sex pheromone cAM373 precursor; Region: CamS_repeat_1; cd13441
1088720002760	putative dimer interface [polypeptide binding]; other site
1088720002761	CamS sex pheromone cAM373 precursor; Region: CamS; pfam07537
1088720002762	C-terminal repeat domain of CamS sex pheromone cAM373 precursor; Region: CamS_repeat_2; cd13440
1088720002763	putative dimer interface [polypeptide binding]; other site
1088720002764	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
1088720002765	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
1088720002766	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
1088720002767	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
1088720002768	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
1088720002769	GatB domain; Region: GatB_Yqey; smart00845
1088720002770	putative lipid kinase; Reviewed; Region: PRK13055
1088720002771	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
1088720002772	TRAM domain; Region: TRAM; pfam01938
1088720002773	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
1088720002774	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1088720002775	S-adenosylmethionine binding site [chemical binding]; other site
1088720002776	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720002777	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1088720002778	putative substrate translocation pore; other site
1088720002779	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1088720002780	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1088720002781	active site
1088720002782	motif I; other site
1088720002783	motif II; other site
1088720002784	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1088720002785	polyphosphate:nucleotide phosphotransferase, PPK2 family; Region: PPK2_rel_1; TIGR03709
1088720002786	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
1088720002787	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
1088720002788	active site
1088720002789	Zn binding site [ion binding]; other site
1088720002790	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1088720002791	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1088720002792	Coenzyme A binding pocket [chemical binding]; other site
1088720002793	EDD domain protein, DegV family; Region: DegV; TIGR00762
1088720002794	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
1088720002795	HflC protein; Region: hflC; TIGR01932
1088720002796	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
1088720002797	Uncharacterized bacterial muramidase containing a glycosyl hydrolase family 25 (GH25) catalytic domain. Endo-N-acetylmuramidases are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis...; Region: GH25_muramidase_2; cd06419
1088720002798	active site
1088720002799	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
1088720002800	Protein of unknown function (DUF1093); Region: DUF1093; cl02185
1088720002801	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1088720002802	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1088720002803	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1088720002804	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1088720002805	ATP binding site [chemical binding]; other site
1088720002806	putative Mg++ binding site [ion binding]; other site
1088720002807	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1088720002808	nucleotide binding region [chemical binding]; other site
1088720002809	ATP-binding site [chemical binding]; other site
1088720002810	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cl00166
1088720002811	active site
1088720002812	methionine cluster; other site
1088720002813	phosphorylation site [posttranslational modification]
1088720002814	metal binding site [ion binding]; metal-binding site
1088720002815	Domain of unknown function (DUF3284); Region: DUF3284; pfam11687
1088720002816	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
1088720002817	active site
1088720002818	ATP-dependent DNA helicase RecQ; Region: recQ; TIGR01389
1088720002819	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1088720002820	ATP binding site [chemical binding]; other site
1088720002821	putative Mg++ binding site [ion binding]; other site
1088720002822	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1088720002823	nucleotide binding region [chemical binding]; other site
1088720002824	ATP-binding site [chemical binding]; other site
1088720002825	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
1088720002826	HRDC domain; Region: HRDC; pfam00570
1088720002827	Thermophilic metalloprotease (M29); Region: Peptidase_M29; pfam02073
1088720002828	Leucyl aminopeptidase (aminopeptidase T) [Amino acid transport and metabolism]; Region: AmpS; COG2309
1088720002829	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1088720002830	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1088720002831	WHG domain; Region: WHG; pfam13305
1088720002832	Uncharacterized protein conserved in bacteria (DUF2252); Region: DUF2252; pfam10009
1088720002833	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4320
1088720002834	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
1088720002835	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1088720002836	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1088720002837	active site
1088720002838	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1088720002839	active site
1088720002840	Protein of unknown function (DUF2922); Region: DUF2922; pfam11148
1088720002841	Citrate synthase (CS), citryl-CoA lyase (CCL), the C-terminal portion of the single-subunit type ATP-citrate lyase (ACL) and the C-terminal portion of the large subunit of the two-subunit type ACL. CS catalyzes the condensation of acetyl coenzyme A; Region: CS_ACL-C_CCL; cl00416
1088720002842	phosphomevalonate kinase, ERG8-type, Gram-positive branch; Region: Pmev_kin_Gr_pos; TIGR01220
1088720002843	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1088720002844	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1088720002845	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1088720002846	active site
1088720002847	tetramer interface; other site
1088720002848	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1088720002849	active site
1088720002850	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
1088720002851	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1088720002852	active site
1088720002853	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
1088720002854	beta-1,6-galactofuranosyltransferase; Provisional; Region: PRK09814
1088720002855	SecA DEAD-like domain; Region: SecA_DEAD; smart00957
1088720002856	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1088720002857	ATP binding site [chemical binding]; other site
1088720002858	SecA preprotein cross-linking domain; Region: SecA_PP_bind; cl03078
1088720002859	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1088720002860	beta-galactosidase; Region: BGL; TIGR03356
1088720002861	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1088720002862	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
1088720002863	active site turn [active]
1088720002864	phosphorylation site [posttranslational modification]
1088720002865	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1088720002866	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
1088720002867	HPr interaction site; other site
1088720002868	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1088720002869	active site
1088720002870	phosphorylation site [posttranslational modification]
1088720002871	Bacterial membrane protein YfhO; Region: YfhO; pfam09586
1088720002872	Bacterial membrane protein YfhO; Region: YfhO; pfam09586
1088720002873	Fic/DOC family; Region: Fic; pfam02661
1088720002874	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
1088720002875	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1088720002876	Ligand binding site; other site
1088720002877	Putative Catalytic site; other site
1088720002878	DXD motif; other site
1088720002879	Predicted membrane protein [Function unknown]; Region: COG4129
1088720002880	Bacterial protein of unknown function (DUF939); Region: DUF939; pfam06081
1088720002881	DUF939 C-terminal domain; Region: DUF939_C; pfam11728
1088720002882	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1088720002883	DNA-binding site [nucleotide binding]; DNA binding site
1088720002884	RNA-binding motif; other site
1088720002885	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1088720002886	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
1088720002887	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1088720002888	active site
1088720002889	xanthine permease; Region: pbuX; TIGR03173
1088720002890	phosphoribosylaminoimidazole carboxylase, PurK protein; Region: purK; TIGR01161
1088720002891	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1088720002892	adenylosuccinate lyase; Provisional; Region: PRK07492
1088720002893	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
1088720002894	tetramer interface [polypeptide binding]; other site
1088720002895	active site
1088720002896	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
1088720002897	Sulfatase; Region: Sulfatase; pfam00884
1088720002898	Glycopeptide antibiotics resistance protein [Defense mechanisms]; Region: VanZ; COG4767
1088720002899	Sugar transport protein; Region: Sugar_transport; pfam06800
1088720002900	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14097
1088720002901	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
1088720002902	active site
1088720002903	dimer interface [polypeptide binding]; other site
1088720002904	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
1088720002905	dimer interface [polypeptide binding]; other site
1088720002906	active site
1088720002907	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1088720002908	DNA/RNA non-specific endonuclease; Region: Endonuclea_NS_2; cl17626
1088720002909	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
1088720002910	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1088720002911	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1088720002912	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1088720002913	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1088720002914	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1088720002915	nucleoside/Zn binding site; other site
1088720002916	dimer interface [polypeptide binding]; other site
1088720002917	catalytic motif [active]
1088720002918	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1088720002919	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720002920	Peptidase family C69; Region: Peptidase_C69; pfam03577
1088720002921	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1088720002922	catalytic core [active]
1088720002923	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1088720002924	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1088720002925	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1088720002926	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1088720002927	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720002928	Walker A/P-loop; other site
1088720002929	ATP binding site [chemical binding]; other site
1088720002930	Q-loop/lid; other site
1088720002931	ABC transporter signature motif; other site
1088720002932	Walker B; other site
1088720002933	D-loop; other site
1088720002934	H-loop/switch region; other site
1088720002935	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1088720002936	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1088720002937	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
1088720002938	Walker A/P-loop; other site
1088720002939	ATP binding site [chemical binding]; other site
1088720002940	Q-loop/lid; other site
1088720002941	ABC transporter signature motif; other site
1088720002942	Walker B; other site
1088720002943	D-loop; other site
1088720002944	H-loop/switch region; other site
1088720002945	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
1088720002946	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1088720002947	Predicted ring-cleavage extradiol dioxygenase [General function prediction only]; Region: COG2514
1088720002948	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
1088720002949	active site
1088720002950	metal binding site [ion binding]; metal-binding site
1088720002951	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
1088720002952	active site
1088720002953	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1088720002954	Beta-lactamase; Region: Beta-lactamase; pfam00144
1088720002955	UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurE; COG0769
1088720002956	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1088720002957	Domain of unknown function (DUF1727); Region: DUF1727; pfam08353
1088720002958	thymidine kinase; Provisional; Region: PRK04296
1088720002959	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1088720002960	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1088720002961	RF-1 domain; Region: RF-1; pfam00472
1088720002962	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
1088720002963	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1088720002964	S-adenosylmethionine binding site [chemical binding]; other site
1088720002965	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
1088720002966	Putative GTP-binding controlling metal-binding; Region: SUA5; pfam03481
1088720002967	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
1088720002968	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1088720002969	dimer interface [polypeptide binding]; other site
1088720002970	active site
1088720002971	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1088720002972	folate binding site [chemical binding]; other site
1088720002973	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1088720002974	active site
1088720002975	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
1088720002976	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
1088720002977	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
1088720002978	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
1088720002979	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
1088720002980	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
1088720002981	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
1088720002982	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
1088720002983	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1088720002984	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
1088720002985	beta subunit interaction interface [polypeptide binding]; other site
1088720002986	Walker A motif; other site
1088720002987	ATP binding site [chemical binding]; other site
1088720002988	Walker B motif; other site
1088720002989	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1088720002990	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1088720002991	core domain interface [polypeptide binding]; other site
1088720002992	delta subunit interface [polypeptide binding]; other site
1088720002993	epsilon subunit interface [polypeptide binding]; other site
1088720002994	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
1088720002995	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1088720002996	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1088720002997	alpha subunit interaction interface [polypeptide binding]; other site
1088720002998	Walker A motif; other site
1088720002999	ATP binding site [chemical binding]; other site
1088720003000	Walker B motif; other site
1088720003001	inhibitor binding site; inhibition site
1088720003002	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1088720003003	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
1088720003004	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
1088720003005	gamma subunit interface [polypeptide binding]; other site
1088720003006	epsilon subunit interface [polypeptide binding]; other site
1088720003007	LBP interface [polypeptide binding]; other site
1088720003008	Protein of unknown function (DUF1146); Region: DUF1146; cl11486
1088720003009	rod shape-determining protein MreB; Provisional; Region: PRK13930
1088720003010	MreB and similar proteins; Region: MreB_like; cd10225
1088720003011	nucleotide binding site [chemical binding]; other site
1088720003012	Mg binding site [ion binding]; other site
1088720003013	putative protofilament interaction site [polypeptide binding]; other site
1088720003014	RodZ interaction site [polypeptide binding]; other site
1088720003015	DNA-directed RNA polymerase subunit beta; Region: EpuA; pfam11772
1088720003016	Haemolytic domain; Region: Haemolytic; cl00506
1088720003017	Protein of unknown function (DUF2969); Region: DUF2969; pfam11184
1088720003018	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
1088720003019	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
1088720003020	lipoyl attachment site [posttranslational modification]; other site
1088720003021	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK08588
1088720003022	Peptidase M20 acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase (ArgE/DapE)-like; Region: M20_ArgE_DapE_like; cd08659
1088720003023	metal binding site [ion binding]; metal-binding site
1088720003024	dimer interface [polypeptide binding]; other site
1088720003025	cytoplasmic membrane lipoprotein-28; Provisional; Region: PRK09861
1088720003026	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1088720003027	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1088720003028	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1088720003029	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
1088720003030	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1088720003031	Walker A/P-loop; other site
1088720003032	ATP binding site [chemical binding]; other site
1088720003033	Q-loop/lid; other site
1088720003034	ABC transporter signature motif; other site
1088720003035	Walker B; other site
1088720003036	D-loop; other site
1088720003037	H-loop/switch region; other site
1088720003038	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
1088720003039	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1088720003040	dimer interface [polypeptide binding]; other site
1088720003041	conserved gate region; other site
1088720003042	ABC-ATPase subunit interface; other site
1088720003043	Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones]; Region: sufC; COG0396
1088720003044	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
1088720003045	Walker A/P-loop; other site
1088720003046	ATP binding site [chemical binding]; other site
1088720003047	Q-loop/lid; other site
1088720003048	ABC transporter signature motif; other site
1088720003049	Walker B; other site
1088720003050	D-loop; other site
1088720003051	H-loop/switch region; other site
1088720003052	Uncharacterized protein family (UPF0051); Region: UPF0051; pfam01458
1088720003053	FeS assembly protein SufD; Region: sufD; TIGR01981
1088720003054	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1088720003055	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1088720003056	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1088720003057	catalytic residue [active]
1088720003058	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
1088720003059	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
1088720003060	trimerization site [polypeptide binding]; other site
1088720003061	active site
1088720003062	FeS assembly protein SufB; Region: sufB; TIGR01980
1088720003063	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814; cl03223
1088720003064	Protein of unknown function (DUF1694); Region: DUF1694; pfam07997
1088720003065	Protein of unknown function (DUF2785); Region: DUF2785; pfam10978
1088720003066	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1088720003067	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1088720003068	non-specific DNA binding site [nucleotide binding]; other site
1088720003069	salt bridge; other site
1088720003070	sequence-specific DNA binding site [nucleotide binding]; other site
1088720003071	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1088720003072	Ligand Binding Site [chemical binding]; other site
1088720003073	recombination factor protein RarA; Reviewed; Region: PRK13342
1088720003074	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1088720003075	Walker A motif; other site
1088720003076	ATP binding site [chemical binding]; other site
1088720003077	Walker B motif; other site
1088720003078	arginine finger; other site
1088720003079	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
1088720003080	bifunctional glutamate--cysteine ligase/glutathione synthetase; Provisional; Region: PRK02471
1088720003081	Protein of unknown function (DUF1694); Region: DUF1694; pfam07997
1088720003082	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4493
1088720003083	Protein of unknown function (DUF1054); Region: DUF1054; pfam06335
1088720003084	L-serine dehydratase, iron-sulfur-dependent, beta subunit; Region: sda_beta; TIGR00719
1088720003085	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1088720003086	C-terminal ACT domain of the L-serine dehydratase (LSD), iron-sulfur-dependent, beta subunit; Region: ACT_LSD; cd04903
1088720003087	putative L-serine binding site [chemical binding]; other site
1088720003088	Serine dehydratase alpha chain; Region: SDH_alpha; cl12120
1088720003089	L-serine deaminase [Amino acid transport and metabolism]; Region: SdaA; COG1760
1088720003090	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1088720003091	bifunctional RNase H/acid phosphatase; Provisional; Region: PRK07238
1088720003092	catalytic core [active]
1088720003093	Enterocin A Immunity; Region: EntA_Immun; pfam08951
1088720003094	methionine sulfoxide reductase A; Provisional; Region: PRK14054
1088720003095	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1088720003096	NAD(P) binding site [chemical binding]; other site
1088720003097	active site
1088720003098	Nicotinamide mononucleotide transporter; Region: NMN_transporter; pfam04973
1088720003099	Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428
1088720003100	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
1088720003101	active site
1088720003102	hypothetical protein; Provisional; Region: PRK07329
1088720003103	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
1088720003104	active site
1088720003105	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1088720003106	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1088720003107	peptide binding site [polypeptide binding]; other site
1088720003108	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1088720003109	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1088720003110	dimer interface [polypeptide binding]; other site
1088720003111	phosphorylation site [posttranslational modification]
1088720003112	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1088720003113	ATP binding site [chemical binding]; other site
1088720003114	Mg2+ binding site [ion binding]; other site
1088720003115	G-X-G motif; other site
1088720003116	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1088720003117	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1088720003118	active site
1088720003119	phosphorylation site [posttranslational modification]
1088720003120	intermolecular recognition site; other site
1088720003121	dimerization interface [polypeptide binding]; other site
1088720003122	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1088720003123	DNA binding site [nucleotide binding]
1088720003124	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1088720003125	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720003126	Walker A/P-loop; other site
1088720003127	ATP binding site [chemical binding]; other site
1088720003128	Q-loop/lid; other site
1088720003129	ABC transporter signature motif; other site
1088720003130	Walker B; other site
1088720003131	D-loop; other site
1088720003132	H-loop/switch region; other site
1088720003133	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1088720003134	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1088720003135	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1088720003136	dimerization interface [polypeptide binding]; other site
1088720003137	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
1088720003138	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
1088720003139	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1088720003140	Coenzyme A binding pocket [chemical binding]; other site
1088720003141	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1088720003142	Coenzyme A binding pocket [chemical binding]; other site
1088720003143	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1088720003144	Coenzyme A binding pocket [chemical binding]; other site
1088720003145	EDD domain protein, DegV family; Region: DegV; TIGR00762
1088720003146	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
1088720003147	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1088720003148	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1088720003149	active site
1088720003150	phosphorylation site [posttranslational modification]
1088720003151	intermolecular recognition site; other site
1088720003152	dimerization interface [polypeptide binding]; other site
1088720003153	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1088720003154	DNA binding residues [nucleotide binding]
1088720003155	dimerization interface [polypeptide binding]; other site
1088720003156	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1088720003157	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1088720003158	Walker A/P-loop; other site
1088720003159	ATP binding site [chemical binding]; other site
1088720003160	Q-loop/lid; other site
1088720003161	ABC transporter signature motif; other site
1088720003162	Walker B; other site
1088720003163	D-loop; other site
1088720003164	H-loop/switch region; other site
1088720003165	Protein of unknown function C-terminus (DUF2399); Region: DUF2399; pfam09664
1088720003166	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1088720003167	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
1088720003168	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
1088720003169	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
1088720003170	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
1088720003171	RNA binding site [nucleotide binding]; other site
1088720003172	Predicted glutamine amidotransferases [General function prediction only]; Region: COG2071
1088720003173	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
1088720003174	catalytic triad [active]
1088720003175	amino acid transporter; Region: 2A0306; TIGR00909
1088720003176	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
1088720003177	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1088720003178	cofactor binding site; other site
1088720003179	DNA binding site [nucleotide binding]
1088720003180	substrate interaction site [chemical binding]; other site
1088720003181	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1088720003182	Domain of unknown function (DUF1998); Region: DUF1998; pfam09369
1088720003183	DEAD/DEAH box helicase; Region: DEAD; pfam00270
1088720003184	Helicase conserved C-terminal domain; Region: Helicase_C; pfam00271
1088720003185	ATP-binding site [chemical binding]; other site
1088720003186	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1088720003187	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1088720003188	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1088720003189	RNA binding surface [nucleotide binding]; other site
1088720003190	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
1088720003191	GAF domain; Region: GAF_2; pfam13185
1088720003192	septation ring formation regulator EzrA; Provisional; Region: PRK04778
1088720003193	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
1088720003194	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1088720003195	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1088720003196	catalytic residue [active]
1088720003197	thiamine biosynthesis protein ThiI; Provisional; Region: PRK01565
1088720003198	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
1088720003199	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
1088720003200	Ligand Binding Site [chemical binding]; other site
1088720003201	redox-sensing transcriptional repressor Rex; Provisional; Region: PRK05472
1088720003202	Putative DNA-binding protein N-terminus; Region: Put_DNA-bind_N; pfam06971
1088720003203	CoA binding domain; Region: CoA_binding; pfam02629
1088720003204	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
1088720003205	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1088720003206	active site
1088720003207	HIGH motif; other site
1088720003208	nucleotide binding site [chemical binding]; other site
1088720003209	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1088720003210	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1088720003211	active site
1088720003212	KMSKS motif; other site
1088720003213	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1088720003214	tRNA binding surface [nucleotide binding]; other site
1088720003215	anticodon binding site; other site
1088720003216	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
1088720003217	folylpolyglutamate synthase/dihydrofolate synthase; Region: folC; TIGR01499
1088720003218	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1088720003219	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
1088720003220	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1088720003221	motif II; other site
1088720003222	hypothetical protein; Reviewed; Region: PRK00024
1088720003223	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1088720003224	MPN+ (JAMM) motif; other site
1088720003225	Zinc-binding site [ion binding]; other site
1088720003226	rod shape-determining protein MreB; Provisional; Region: PRK13927
1088720003227	MreB and similar proteins; Region: MreB_like; cd10225
1088720003228	nucleotide binding site [chemical binding]; other site
1088720003229	Mg binding site [ion binding]; other site
1088720003230	putative protofilament interaction site [polypeptide binding]; other site
1088720003231	RodZ interaction site [polypeptide binding]; other site
1088720003232	rod shape-determining protein MreC; Provisional; Region: PRK13922
1088720003233	Protein of unknown function (DUF904); Region: DUF904; pfam06005
1088720003234	rod shape-determining protein MreC; Region: MreC; pfam04085
1088720003235	rod shape-determining protein MreD; Region: shape_MreD; TIGR03426
1088720003236	septum formation inhibitor; Reviewed; Region: minC; PRK00513
1088720003237	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
1088720003238	Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning]; Region: MinD; COG2894
1088720003239	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
1088720003240	Switch I; other site
1088720003241	Switch II; other site
1088720003242	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1088720003243	dimer interface [polypeptide binding]; other site
1088720003244	conserved gate region; other site
1088720003245	putative PBP binding loops; other site
1088720003246	ABC-ATPase subunit interface; other site
1088720003247	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1088720003248	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720003249	Walker A/P-loop; other site
1088720003250	ATP binding site [chemical binding]; other site
1088720003251	Q-loop/lid; other site
1088720003252	ABC transporter signature motif; other site
1088720003253	Walker B; other site
1088720003254	D-loop; other site
1088720003255	H-loop/switch region; other site
1088720003256	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1088720003257	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1088720003258	substrate binding pocket [chemical binding]; other site
1088720003259	membrane-bound complex binding site; other site
1088720003260	hinge residues; other site
1088720003261	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
1088720003262	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
1088720003263	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
1088720003264	putative active site [active]
1088720003265	catalytic site [active]
1088720003266	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
1088720003267	putative active site [active]
1088720003268	catalytic site [active]
1088720003269	cell division protein MraZ; Reviewed; Region: PRK00326
1088720003270	MraZ protein; Region: MraZ; pfam02381
1088720003271	MraZ protein; Region: MraZ; pfam02381
1088720003272	MraW methylase family; Region: Methyltransf_5; pfam01795
1088720003273	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
1088720003274	Cell division protein FtsL; Region: FtsL; cl11433
1088720003275	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
1088720003276	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1088720003277	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1088720003278	PASTA domain of PBP2x-like proteins, first repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_1; cd06576
1088720003279	PASTA domain of PBP2x-like proteins, second repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_2; cd06575
1088720003280	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
1088720003281	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1088720003282	Mg++ binding site [ion binding]; other site
1088720003283	putative catalytic motif [active]
1088720003284	putative substrate binding site [chemical binding]; other site
1088720003285	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK02472
1088720003286	Alanine dehydrogenase/PNT, C-terminal domain; Region: AlaDh_PNT_C; smart01002
1088720003287	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1088720003288	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1088720003289	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
1088720003290	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1088720003291	active site
1088720003292	homodimer interface [polypeptide binding]; other site
1088720003293	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
1088720003294	Cell division protein FtsQ; Region: FtsQ; pfam03799
1088720003295	Cell division ATPase FtsA [Cell division and chromosome partitioning]; Region: ftsA; COG0849
1088720003296	Cell division protein FtsA; Region: FtsA; smart00842
1088720003297	Cell division protein FtsA; Region: FtsA; pfam14450
1088720003298	cell division protein FtsZ; Validated; Region: PRK09330
1088720003299	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1088720003300	nucleotide binding site [chemical binding]; other site
1088720003301	SulA interaction site; other site
1088720003302	Protein of unknown function (DUF552); Region: DUF552; pfam04472
1088720003303	YGGT family; Region: YGGT; pfam02325
1088720003304	Uncharacterized conserved protein, contains S4-like domain [Function unknown]; Region: COG2302
1088720003305	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1088720003306	RNA binding surface [nucleotide binding]; other site
1088720003307	DivIVA protein; Region: DivIVA; pfam05103
1088720003308	DivIVA domain; Region: DivI1A_domain; TIGR03544
1088720003309	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
1088720003310	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
1088720003311	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1088720003312	active site
1088720003313	HIGH motif; other site
1088720003314	nucleotide binding site [chemical binding]; other site
1088720003315	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1088720003316	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1088720003317	active site
1088720003318	KMSKS motif; other site
1088720003319	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
1088720003320	tRNA binding surface [nucleotide binding]; other site
1088720003321	anticodon binding site; other site
1088720003322	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1088720003323	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1088720003324	DNA-binding site [nucleotide binding]; DNA binding site
1088720003325	RNA-binding motif; other site
1088720003326	PBP superfamily domain; Region: PBP_like_2; cl17296
1088720003327	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1088720003328	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720003329	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1088720003330	putative substrate translocation pore; other site
1088720003331	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720003332	Toxic anion resistance protein (TelA); Region: TelA; pfam05816
1088720003333	5-bromo-4-chloroindolyl phosphate hydrolysis protein; Region: Halogen_Hydrol; pfam10112
1088720003334	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1088720003335	dimer interface [polypeptide binding]; other site
1088720003336	ADP-ribose binding site [chemical binding]; other site
1088720003337	active site
1088720003338	nudix motif; other site
1088720003339	metal binding site [ion binding]; metal-binding site
1088720003340	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
1088720003341	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
1088720003342	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1088720003343	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
1088720003344	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1088720003345	catalytic residue [active]
1088720003346	Putative amino acid metabolism; Region: DUF1831; pfam08866
1088720003347	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720003348	Excinuclease ATPase subunit [DNA replication, recombination, and repair]; Region: UvrA; COG0178
1088720003349	Walker A/P-loop; other site
1088720003350	ATP binding site [chemical binding]; other site
1088720003351	Q-loop/lid; other site
1088720003352	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720003353	ABC transporter signature motif; other site
1088720003354	Walker B; other site
1088720003355	D-loop; other site
1088720003356	H-loop/switch region; other site
1088720003357	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720003358	Walker A/P-loop; other site
1088720003359	ATP binding site [chemical binding]; other site
1088720003360	Q-loop/lid; other site
1088720003361	ABC transporter signature motif; other site
1088720003362	Walker B; other site
1088720003363	D-loop; other site
1088720003364	H-loop/switch region; other site
1088720003365	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
1088720003366	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1088720003367	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1088720003368	catalytic core [active]
1088720003369	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1088720003370	TPR motif; other site
1088720003371	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
1088720003372	H3TH domains of structure-specific 5' nucleases (or flap endonuclease-1-like) involved in DNA replication, repair, and recombination; Region: H3TH_StructSpec-5'-nucleases; cl14815
1088720003373	AAA domain; Region: AAA_30; pfam13604
1088720003374	Family description; Region: UvrD_C_2; pfam13538
1088720003375	Acetyltransferase (GNAT) domain; Region: Acetyltransf_9; pfam13527
1088720003376	Sterol carrier protein domain; Region: SCP2_2; pfam13530
1088720003377	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
1088720003378	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
1088720003379	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
1088720003380	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
1088720003381	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
1088720003382	hypothetical protein; Provisional; Region: PRK13667
1088720003383	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1088720003384	active site
1088720003385	catalytic residues [active]
1088720003386	metal binding site [ion binding]; metal-binding site
1088720003387	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1088720003388	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_x; TIGR03181
1088720003389	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
1088720003390	TPP-binding site [chemical binding]; other site
1088720003391	tetramer interface [polypeptide binding]; other site
1088720003392	heterodimer interface [polypeptide binding]; other site
1088720003393	phosphorylation loop region [posttranslational modification]
1088720003394	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
1088720003395	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
1088720003396	alpha subunit interface [polypeptide binding]; other site
1088720003397	TPP binding site [chemical binding]; other site
1088720003398	heterodimer interface [polypeptide binding]; other site
1088720003399	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1088720003400	dihydrolipoamide acetyltransferase; Reviewed; Region: PRK11855
1088720003401	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1088720003402	E3 interaction surface; other site
1088720003403	lipoyl attachment site [posttranslational modification]; other site
1088720003404	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1088720003405	E3 interaction surface; other site
1088720003406	lipoyl attachment site [posttranslational modification]; other site
1088720003407	e3 binding domain; Region: E3_binding; pfam02817
1088720003408	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1088720003409	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06416
1088720003410	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1088720003411	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1088720003412	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1088720003413	NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195
1088720003414	substrate binding site [chemical binding]; other site
1088720003415	Uncharacterized protein family (UPF0223); Region: UPF0223; pfam05256
1088720003416	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1088720003417	Inositol-monophosphatase-like domains. This family of phosphatases is dependent on bivalent metal ions such as Mg++, and many members are inhibited by Li+ (which is thought to displace a bivalent ion in the active site). Substrates include fructose-1; Region: IMPase_like; cd01637
1088720003418	active site
1088720003419	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
1088720003420	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
1088720003421	G1 box; other site
1088720003422	putative GEF interaction site [polypeptide binding]; other site
1088720003423	GTP/Mg2+ binding site [chemical binding]; other site
1088720003424	Switch I region; other site
1088720003425	G2 box; other site
1088720003426	G3 box; other site
1088720003427	Switch II region; other site
1088720003428	G4 box; other site
1088720003429	G5 box; other site
1088720003430	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
1088720003431	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
1088720003432	cell division protein FtsW; Region: ftsW; TIGR02614
1088720003433	pyruvate carboxylase; Reviewed; Region: PRK12999
1088720003434	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1088720003435	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1088720003436	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1088720003437	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
1088720003438	active site
1088720003439	catalytic residues [active]
1088720003440	metal binding site [ion binding]; metal-binding site
1088720003441	homodimer binding site [polypeptide binding]; other site
1088720003442	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1088720003443	carboxyltransferase (CT) interaction site; other site
1088720003444	biotinylation site [posttranslational modification]; other site
1088720003445	Uncharacterized protein conserved in bacteria (DUF2129); Region: DUF2129; pfam09902
1088720003446	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
1088720003447	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1088720003448	S-adenosylmethionine binding site [chemical binding]; other site
1088720003449	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
1088720003450	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
1088720003451	active site
1088720003452	(T/H)XGH motif; other site
1088720003453	Predicted secreted protein containing a PDZ domain [Signal transduction mechanisms]; Region: SdrC; COG3480
1088720003454	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
1088720003455	protein binding site [polypeptide binding]; other site
1088720003456	SLBB domain; Region: SLBB; pfam10531
1088720003457	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
1088720003458	Helix-hairpin-helix motif; Region: HHH; pfam00633
1088720003459	Competence protein; Region: Competence; pfam03772
1088720003460	Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658
1088720003461	Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333
1088720003462	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1088720003463	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
1088720003464	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
1088720003465	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1088720003466	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1088720003467	16S/18S rRNA binding site [nucleotide binding]; other site
1088720003468	S13e-L30e interaction site [polypeptide binding]; other site
1088720003469	25S rRNA binding site [nucleotide binding]; other site
1088720003470	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
1088720003471	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1088720003472	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
1088720003473	elongation factor Tu; Reviewed; Region: PRK00049
1088720003474	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1088720003475	G1 box; other site
1088720003476	GEF interaction site [polypeptide binding]; other site
1088720003477	GTP/Mg2+ binding site [chemical binding]; other site
1088720003478	Switch I region; other site
1088720003479	G2 box; other site
1088720003480	G3 box; other site
1088720003481	Switch II region; other site
1088720003482	G4 box; other site
1088720003483	G5 box; other site
1088720003484	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1088720003485	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1088720003486	Antibiotic Binding Site [chemical binding]; other site
1088720003487	Protein of unknown function (DUF3737); Region: DUF3737; pfam12541
1088720003488	NAD-dependent deacetylase; Provisional; Region: PRK00481
1088720003489	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
1088720003490	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
1088720003491	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
1088720003492	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1088720003493	DNA binding residues [nucleotide binding]
1088720003494	putative dimer interface [polypeptide binding]; other site
1088720003495	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1088720003496	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1088720003497	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1088720003498	Walker A/P-loop; other site
1088720003499	ATP binding site [chemical binding]; other site
1088720003500	Q-loop/lid; other site
1088720003501	ABC transporter signature motif; other site
1088720003502	Walker B; other site
1088720003503	D-loop; other site
1088720003504	H-loop/switch region; other site
1088720003505	trigger factor; Provisional; Region: tig; PRK01490
1088720003506	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1088720003507	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1088720003508	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1088720003509	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
1088720003510	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1088720003511	Walker A motif; other site
1088720003512	ATP binding site [chemical binding]; other site
1088720003513	Walker B motif; other site
1088720003514	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1088720003515	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
1088720003516	Elongation factor Tu GTP binding domain; Region: GTP_EFTU; pfam00009
1088720003517	G1 box; other site
1088720003518	GTP/Mg2+ binding site [chemical binding]; other site
1088720003519	Switch I region; other site
1088720003520	G2 box; other site
1088720003521	G3 box; other site
1088720003522	Switch II region; other site
1088720003523	G4 box; other site
1088720003524	G5 box; other site
1088720003525	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in a group of uncharacterized proteins from bacteria and archaea; Region: NTP-PPase_u4; cd11541
1088720003526	putative metal binding site [ion binding]; other site
1088720003527	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1088720003528	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1088720003529	substrate binding pocket [chemical binding]; other site
1088720003530	membrane-bound complex binding site; other site
1088720003531	hinge residues; other site
1088720003532	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1088720003533	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1088720003534	dimer interface [polypeptide binding]; other site
1088720003535	conserved gate region; other site
1088720003536	putative PBP binding loops; other site
1088720003537	ABC-ATPase subunit interface; other site
1088720003538	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1088720003539	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1088720003540	Walker A/P-loop; other site
1088720003541	ATP binding site [chemical binding]; other site
1088720003542	Q-loop/lid; other site
1088720003543	ABC transporter signature motif; other site
1088720003544	Walker B; other site
1088720003545	D-loop; other site
1088720003546	H-loop/switch region; other site
1088720003547	Pleckstrin homology-like domain; Region: PH-like; cl17171
1088720003548	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
1088720003549	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1088720003550	GIY-YIG motif/motif A; other site
1088720003551	active site
1088720003552	catalytic site [active]
1088720003553	putative DNA binding site [nucleotide binding]; other site
1088720003554	metal binding site [ion binding]; metal-binding site
1088720003555	UvrB/uvrC motif; Region: UVR; pfam02151
1088720003556	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1088720003557	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
1088720003558	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1088720003559	active site
1088720003560	phosphorylation site [posttranslational modification]
1088720003561	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1088720003562	active site
1088720003563	P-loop; other site
1088720003564	phosphorylation site [posttranslational modification]
1088720003565	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1088720003566	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
1088720003567	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1088720003568	putative substrate binding site [chemical binding]; other site
1088720003569	putative ATP binding site [chemical binding]; other site
1088720003570	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1088720003571	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1088720003572	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1088720003573	GTPase CgtA; Reviewed; Region: obgE; PRK12297
1088720003574	GTP1/OBG; Region: GTP1_OBG; pfam01018
1088720003575	Obg GTPase; Region: Obg; cd01898
1088720003576	G1 box; other site
1088720003577	GTP/Mg2+ binding site [chemical binding]; other site
1088720003578	Switch I region; other site
1088720003579	G2 box; other site
1088720003580	G3 box; other site
1088720003581	Switch II region; other site
1088720003582	G4 box; other site
1088720003583	G5 box; other site
1088720003584	Domain of unknown function (DUF1967); Region: DUF1967; pfam09269
1088720003585	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1088720003586	yrhL-like subfamily of SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_yrhL_like; cd01840
1088720003587	catalytic triad [active]
1088720003588	catalytic triad [active]
1088720003589	oxyanion hole [active]
1088720003590	ribonuclease Z; Region: RNase_Z; TIGR02651
1088720003591	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
1088720003592	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1088720003593	NAD(P) binding site [chemical binding]; other site
1088720003594	active site
1088720003595	Protein of unknown function (DUF1049); Region: DUF1049; pfam06305
1088720003596	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
1088720003597	Clp amino terminal domain; Region: Clp_N; pfam02861
1088720003598	Clp amino terminal domain; Region: Clp_N; pfam02861
1088720003599	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1088720003600	Walker A motif; other site
1088720003601	ATP binding site [chemical binding]; other site
1088720003602	Walker B motif; other site
1088720003603	arginine finger; other site
1088720003604	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1088720003605	Walker A motif; other site
1088720003606	ATP binding site [chemical binding]; other site
1088720003607	Walker B motif; other site
1088720003608	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1088720003609	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
1088720003610	Domain of unknown function (DUF1836); Region: DUF1836; pfam08876
1088720003611	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
1088720003612	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
1088720003613	active site
1088720003614	metal binding site [ion binding]; metal-binding site
1088720003615	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1088720003616	Protein of unknown function (DUF2929); Region: DUF2929; pfam11151
1088720003617	DNA polymerase III, alpha subunit [DNA replication, recombination, and repair]; Region: DnaE; COG0587
1088720003618	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III; Region: PHP_PolIIIA; cd07431
1088720003619	active site
1088720003620	PHP Thumb interface [polypeptide binding]; other site
1088720003621	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
1088720003622	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1088720003623	generic binding surface I; other site
1088720003624	generic binding surface II; other site
1088720003625	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
1088720003626	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
1088720003627	active site
1088720003628	ADP/pyrophosphate binding site [chemical binding]; other site
1088720003629	dimerization interface [polypeptide binding]; other site
1088720003630	allosteric effector site; other site
1088720003631	fructose-1,6-bisphosphate binding site; other site
1088720003632	pyruvate kinase; Provisional; Region: PRK06354
1088720003633	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
1088720003634	domain interfaces; other site
1088720003635	active site
1088720003636	Phosphohistidine swiveling domain [Signal transduction mechanisms]; Region: COG3848
1088720003637	Protein of unknown function (DUF441); Region: DUF441; pfam04284
1088720003638	Predicted RNA-bindining protein (contains S1 and HTH domains) [General function prediction only]; Region: COG2996
1088720003639	S1 domain; Region: S1_2; pfam13509
1088720003640	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1088720003641	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
1088720003642	active site
1088720003643	Int/Topo IB signature motif; other site
1088720003644	segregation and condensation protein A; Reviewed; Region: scpA; PRK00104
1088720003645	segregation and condensation protein B; Reviewed; Region: scpB; PRK00135
1088720003646	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
1088720003647	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1088720003648	RNA binding surface [nucleotide binding]; other site
1088720003649	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
1088720003650	active site
1088720003651	4Fe-4S single cluster domain; Region: Fer4_13; pfam13370
1088720003652	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4955
1088720003653	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1088720003654	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1088720003655	ATP binding site [chemical binding]; other site
1088720003656	putative Mg++ binding site [ion binding]; other site
1088720003657	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1088720003658	nucleotide binding region [chemical binding]; other site
1088720003659	ATP-binding site [chemical binding]; other site
1088720003660	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1088720003661	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1088720003662	cytidylate kinase; Provisional; Region: cmk; PRK00023
1088720003663	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
1088720003664	CMP-binding site; other site
1088720003665	The sites determining sugar specificity; other site
1088720003666	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06676
1088720003667	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
1088720003668	RNA binding site [nucleotide binding]; other site
1088720003669	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1088720003670	RNA binding site [nucleotide binding]; other site
1088720003671	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
1088720003672	RNA binding site [nucleotide binding]; other site
1088720003673	S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692
1088720003674	RNA binding site [nucleotide binding]; other site
1088720003675	GTP-binding protein Der; Reviewed; Region: PRK00093
1088720003676	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1088720003677	G1 box; other site
1088720003678	GTP/Mg2+ binding site [chemical binding]; other site
1088720003679	Switch I region; other site
1088720003680	G2 box; other site
1088720003681	Switch II region; other site
1088720003682	G3 box; other site
1088720003683	G4 box; other site
1088720003684	G5 box; other site
1088720003685	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1088720003686	G1 box; other site
1088720003687	GTP/Mg2+ binding site [chemical binding]; other site
1088720003688	Switch I region; other site
1088720003689	G2 box; other site
1088720003690	G3 box; other site
1088720003691	Switch II region; other site
1088720003692	G4 box; other site
1088720003693	G5 box; other site
1088720003694	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1088720003695	IHF dimer interface [polypeptide binding]; other site
1088720003696	IHF - DNA interface [nucleotide binding]; other site
1088720003697	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1088720003698	binding surface
1088720003699	TPR motif; other site
1088720003700	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1088720003701	binding surface
1088720003702	TPR repeat; Region: TPR_11; pfam13414
1088720003703	TPR motif; other site
1088720003704	TPR repeat; Region: TPR_11; pfam13414
1088720003705	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1088720003706	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1088720003707	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1088720003708	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1088720003709	tRNA CCA-pyrophosphorylase; Provisional; Region: PRK13299
1088720003710	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1088720003711	active site
1088720003712	NTP binding site [chemical binding]; other site
1088720003713	metal binding triad [ion binding]; metal-binding site
1088720003714	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1088720003715	tRNA nucleotidyltransferase domain 2 putative; Region: tRNA_NucTran2_2; pfam13735
1088720003716	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1088720003717	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1088720003718	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1088720003719	ABC transporter; Region: ABC_tran_2; pfam12848
1088720003720	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1088720003721	thymidylate synthase; Region: thym_sym; TIGR03284
1088720003722	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
1088720003723	dimerization interface [polypeptide binding]; other site
1088720003724	active site
1088720003725	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1088720003726	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
1088720003727	folate binding site [chemical binding]; other site
1088720003728	NADP+ binding site [chemical binding]; other site
1088720003729	Predicted membrane protein, hemolysin III homolog [General function prediction only]; Region: COG1272
1088720003730	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
1088720003731	EDD domain protein, DegV family; Region: DegV; TIGR00762
1088720003732	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
1088720003733	Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_YpmR_like; cd04506
1088720003734	active site
1088720003735	catalytic triad [active]
1088720003736	oxyanion hole [active]
1088720003737	Uncharacterized protein conserved in bacteria (DUF2140); Region: DUF2140; pfam09911
1088720003738	methionine sulfoxide reductase A; Provisional; Region: PRK14054
1088720003739	hypothetical protein; Provisional; Region: PRK13672
1088720003740	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
1088720003741	C-terminal peptidase (prc); Region: prc; TIGR00225
1088720003742	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1088720003743	protein binding site [polypeptide binding]; other site
1088720003744	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1088720003745	Catalytic dyad [active]
1088720003746	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1088720003747	ribosome biogenesis GTP-binding protein YlqF; Region: GTPase_YlqF; TIGR03596
1088720003748	Circularly permuted YlqF GTPase; Region: YlqF; cd01856
1088720003749	GTP/Mg2+ binding site [chemical binding]; other site
1088720003750	G4 box; other site
1088720003751	G5 box; other site
1088720003752	G1 box; other site
1088720003753	Switch I region; other site
1088720003754	G2 box; other site
1088720003755	G3 box; other site
1088720003756	Switch II region; other site
1088720003757	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
1088720003758	RNA/DNA hybrid binding site [nucleotide binding]; other site
1088720003759	active site
1088720003760	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
1088720003761	DNA protecting protein DprA; Region: dprA; TIGR00732
1088720003762	DNA topoisomerase I; Validated; Region: PRK05582
1088720003763	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
1088720003764	active site
1088720003765	interdomain interaction site; other site
1088720003766	putative metal-binding site [ion binding]; other site
1088720003767	nucleotide binding site [chemical binding]; other site
1088720003768	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1088720003769	domain I; other site
1088720003770	DNA binding groove [nucleotide binding]
1088720003771	phosphate binding site [ion binding]; other site
1088720003772	domain II; other site
1088720003773	domain III; other site
1088720003774	nucleotide binding site [chemical binding]; other site
1088720003775	catalytic site [active]
1088720003776	domain IV; other site
1088720003777	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1088720003778	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1088720003779	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
1088720003780	Glucose inhibited division protein A; Region: GIDA; pfam01134
1088720003781	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1088720003782	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
1088720003783	active site
1088720003784	Int/Topo IB signature motif; other site
1088720003785	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
1088720003786	active site
1088720003787	HslU subunit interaction site [polypeptide binding]; other site
1088720003788	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
1088720003789	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1088720003790	Walker A motif; other site
1088720003791	ATP binding site [chemical binding]; other site
1088720003792	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
1088720003793	Walker B motif; other site
1088720003794	arginine finger; other site
1088720003795	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1088720003796	Aldose 1-epimerase, similar to Lactococcus lactis lacX; Region: Aldose_epim_lacX; cd09024
1088720003797	active site
1088720003798	catalytic residues [active]
1088720003799	membrane protein; Provisional; Region: PRK14392
1088720003800	DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559
1088720003801	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1088720003802	Mg2+ binding site [ion binding]; other site
1088720003803	G-X-G motif; other site
1088720003804	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1088720003805	anchoring element; other site
1088720003806	dimer interface [polypeptide binding]; other site
1088720003807	ATP binding site [chemical binding]; other site
1088720003808	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1088720003809	active site
1088720003810	putative metal-binding site [ion binding]; other site
1088720003811	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1088720003812	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
1088720003813	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1088720003814	CAP-like domain; other site
1088720003815	active site
1088720003816	primary dimer interface [polypeptide binding]; other site
1088720003817	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1088720003818	pyruvate formate-lyase 1-activating enzyme; Region: PFLA; TIGR02493
1088720003819	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1088720003820	FeS/SAM binding site; other site
1088720003821	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1088720003822	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1088720003823	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1088720003824	dimerization interface [polypeptide binding]; other site
1088720003825	putative manganese-dependent inorganic pyrophosphatase; Provisional; Region: PRK05427
1088720003826	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
1088720003827	DHHA2 domain; Region: DHHA2; pfam02833
1088720003828	site-specific tyrosine recombinase XerS; Reviewed; Region: xerS; PRK05084
1088720003829	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1088720003830	active site
1088720003831	DNA binding site [nucleotide binding]
1088720003832	Int/Topo IB signature motif; other site
1088720003833	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1088720003834	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1088720003835	Walker A/P-loop; other site
1088720003836	ATP binding site [chemical binding]; other site
1088720003837	Q-loop/lid; other site
1088720003838	ABC transporter signature motif; other site
1088720003839	Walker B; other site
1088720003840	D-loop; other site
1088720003841	H-loop/switch region; other site
1088720003842	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1088720003843	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1088720003844	ATP binding site [chemical binding]; other site
1088720003845	Mg2+ binding site [ion binding]; other site
1088720003846	G-X-G motif; other site
1088720003847	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1088720003848	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1088720003849	active site
1088720003850	phosphorylation site [posttranslational modification]
1088720003851	intermolecular recognition site; other site
1088720003852	dimerization interface [polypeptide binding]; other site
1088720003853	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1088720003854	DNA binding site [nucleotide binding]
1088720003855	H+ Antiporter protein; Region: 2A0121; TIGR00900
1088720003856	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720003857	putative substrate translocation pore; other site
1088720003858	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1088720003859	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1088720003860	Coenzyme A binding pocket [chemical binding]; other site
1088720003861	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1088720003862	Coenzyme A binding pocket [chemical binding]; other site
1088720003863	Nitroreductase-like family 1. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_1; cd02137
1088720003864	dimer interface [polypeptide binding]; other site
1088720003865	FMN binding site [chemical binding]; other site
1088720003866	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1088720003867	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1088720003868	histidinol-phosphate aminotransferase; Provisional; Region: PRK03158
1088720003869	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1088720003870	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1088720003871	homodimer interface [polypeptide binding]; other site
1088720003872	catalytic residue [active]
1088720003873	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
1088720003874	metal binding site [ion binding]; metal-binding site
1088720003875	phosphoribosyl-AMP cyclohydrolase; Reviewed; Region: hisI; PRK00051
1088720003876	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
1088720003877	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
1088720003878	substrate binding site [chemical binding]; other site
1088720003879	glutamase interaction surface [polypeptide binding]; other site
1088720003880	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
1088720003881	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
1088720003882	catalytic residues [active]
1088720003883	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13141
1088720003884	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
1088720003885	putative active site [active]
1088720003886	oxyanion strand; other site
1088720003887	catalytic triad [active]
1088720003888	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
1088720003889	4-fold oligomerization interface [polypeptide binding]; other site
1088720003890	putative active site pocket [active]
1088720003891	metal binding residues [ion binding]; metal-binding site
1088720003892	3-fold/trimer interface [polypeptide binding]; other site
1088720003893	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
1088720003894	histidinol dehydrogenase; Region: hisD; TIGR00069
1088720003895	NAD binding site [chemical binding]; other site
1088720003896	dimerization interface [polypeptide binding]; other site
1088720003897	product binding site; other site
1088720003898	substrate binding site [chemical binding]; other site
1088720003899	zinc binding site [ion binding]; other site
1088720003900	catalytic residues [active]
1088720003901	ATP phosphoribosyltransferase catalytic subunit; Reviewed; Region: hisG; PRK01686
1088720003902	ATP phosphoribosyltransferase [Amino acid transport and metabolism]; Region: HisG; COG0040
1088720003903	ATP phosphoribosyltransferase, regulatory subunit; Region: hisZ_biosyn_reg; TIGR00443
1088720003904	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1088720003905	dimer interface [polypeptide binding]; other site
1088720003906	motif 1; other site
1088720003907	active site
1088720003908	motif 2; other site
1088720003909	motif 3; other site
1088720003910	histidinol-phosphate aminotransferase; Provisional; Region: PRK03158
1088720003911	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1088720003912	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1088720003913	homodimer interface [polypeptide binding]; other site
1088720003914	catalytic residue [active]
1088720003915	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1088720003916	dimer interface [polypeptide binding]; other site
1088720003917	ADP-ribose binding site [chemical binding]; other site
1088720003918	active site
1088720003919	nudix motif; other site
1088720003920	metal binding site [ion binding]; metal-binding site
1088720003921	EDD domain protein, DegV family; Region: DegV; TIGR00762
1088720003922	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
1088720003923	Fibronectin-binding protein A N-terminus (FbpA); Region: FbpA; pfam05833
1088720003924	Domain of unknown function (DUF814); Region: DUF814; pfam05670
1088720003925	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Sulfolobus solfataricus (Ss) and its homologs from archaea and bacteria; Region: NTP-PPase_SsMazG; cd11535
1088720003926	metal binding site [ion binding]; metal-binding site
1088720003927	Predicted membrane protein, putative toxin regulator [General function prediction only]; Region: PfoR; COG3641
1088720003928	Phosphotransferase system, EIIC; Region: PTS_EIIC_2; pfam13303
1088720003929	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1088720003930	active site
1088720003931	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
1088720003932	active site
1088720003933	dimer interface [polypeptide binding]; other site
1088720003934	Dihydroorotate dehydrogenase (DHOD) class 1B FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine...; Region: DHOD_1B_like; cd04740
1088720003935	dihydroorotate dehydrogenase (subfamily 1) family protein; Region: pyrD_sub1_fam; TIGR01037
1088720003936	heterodimer interface [polypeptide binding]; other site
1088720003937	active site
1088720003938	FMN binding site [chemical binding]; other site
1088720003939	homodimer interface [polypeptide binding]; other site
1088720003940	substrate binding site [chemical binding]; other site
1088720003941	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
1088720003942	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1088720003943	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1088720003944	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
1088720003945	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1088720003946	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1088720003947	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
1088720003948	IMP binding site; other site
1088720003949	dimer interface [polypeptide binding]; other site
1088720003950	interdomain contacts; other site
1088720003951	partial ornithine binding site; other site
1088720003952	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
1088720003953	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
1088720003954	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
1088720003955	catalytic site [active]
1088720003956	subunit interface [polypeptide binding]; other site
1088720003957	dihydroorotase; Validated; Region: pyrC; PRK09357
1088720003958	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1088720003959	Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317
1088720003960	active site
1088720003961	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
1088720003962	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1088720003963	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1088720003964	uracil transporter; Provisional; Region: PRK10720
1088720003965	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
1088720003966	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1088720003967	active site
1088720003968	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1088720003969	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1088720003970	RNA binding surface [nucleotide binding]; other site
1088720003971	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1088720003972	active site
1088720003973	lipoprotein signal peptidase; Provisional; Region: PRK14797
1088720003974	lipoprotein signal peptidase; Provisional; Region: PRK14787
1088720003975	formate--tetrahydrofolate ligase; Provisional; Region: PRK13505
1088720003976	Formyltetrahydrofolate synthetase (FTHFS) catalyzes the ATP-dependent activation of formate ion via its addition to the N10 position of tetrahydrofolate. FTHFS is a highly expressed key enzyme in both the Wood-Ljungdahl pathway of autotrophic CO2...; Region: FTHFS; cd00477
1088720003977	Potassium binding sites [ion binding]; other site
1088720003978	Cesium cation binding sites [ion binding]; other site
1088720003979	RNAse HI family that includes Archaeal RNase HI; Region: RNase_HI_archaeal_like; cd09279
1088720003980	RNA/DNA hybrid binding site [nucleotide binding]; other site
1088720003981	active site
1088720003982	Nitroreductase-like family 4.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_4; cd02140
1088720003983	dimer interface [polypeptide binding]; other site
1088720003984	FMN binding site [chemical binding]; other site
1088720003985	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
1088720003986	cardiolipin synthase; Region: bac_cardiolipin; TIGR04265
1088720003987	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
1088720003988	putative active site [active]
1088720003989	catalytic site [active]
1088720003990	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
1088720003991	putative active site [active]
1088720003992	catalytic site [active]
1088720003993	Mga helix-turn-helix domain; Region: Mga; pfam05043
1088720003994	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
1088720003995	catalytic residues [active]
1088720003996	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK07306
1088720003997	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
1088720003998	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1088720003999	active site
1088720004000	dimer interface [polypeptide binding]; other site
1088720004001	catalytic residues [active]
1088720004002	effector binding site; other site
1088720004003	R2 peptide binding site; other site
1088720004004	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
1088720004005	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1088720004006	dimer interface [polypeptide binding]; other site
1088720004007	putative radical transfer pathway; other site
1088720004008	diiron center [ion binding]; other site
1088720004009	tyrosyl radical; other site
1088720004010	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1088720004011	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1088720004012	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1088720004013	dimerization interface [polypeptide binding]; other site
1088720004014	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
1088720004015	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
1088720004016	active site
1088720004017	Zn binding site [ion binding]; other site
1088720004018	lipoyltransferase and lipoate-protein ligase; Region: lipoyltrans; TIGR00545
1088720004019	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
1088720004020	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
1088720004021	Phosphoglycerate Dehydrogenase, 2-hydroxyacid dehydrogenase family; Region: PGDH_1; cd12155
1088720004022	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
1088720004023	putative ligand binding site [chemical binding]; other site
1088720004024	NAD binding site [chemical binding]; other site
1088720004025	catalytic site [active]
1088720004026	Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0116
1088720004027	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
1088720004028	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1088720004029	cell division protein GpsB; Provisional; Region: PRK14127
1088720004030	DivIVA domain; Region: DivI1A_domain; TIGR03544
1088720004031	hypothetical protein; Provisional; Region: PRK13660
1088720004032	Holliday junction-specific endonuclease; Reviewed; Region: recU; PRK02234
1088720004033	Transglycosylase; Region: Transgly; pfam00912
1088720004034	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
1088720004035	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1088720004036	Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286
1088720004037	catalytic motif [active]
1088720004038	Zn binding site [ion binding]; other site
1088720004039	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
1088720004040	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1088720004041	minor groove reading motif; other site
1088720004042	helix-hairpin-helix signature motif; other site
1088720004043	substrate binding pocket [chemical binding]; other site
1088720004044	active site
1088720004045	Putative primosome component and related proteins [DNA replication, recombination, and repair]; Region: DnaD; COG3935
1088720004046	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
1088720004047	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
1088720004048	AsnRS_cyto_like_N: N-terminal, anticodon recognition domain of the type found in human and Saccharomyces cerevisiae cytoplasmic asparaginyl-tRNA synthetase (AsnRS), in Brugia malayai AsnRs and, in various putative bacterial AsnRSs.  This domain is a...; Region: AsnRS_cyto_like_N; cd04323
1088720004049	putative dimer interface [polypeptide binding]; other site
1088720004050	putative anticodon binding site; other site
1088720004051	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
1088720004052	homodimer interface [polypeptide binding]; other site
1088720004053	motif 1; other site
1088720004054	motif 2; other site
1088720004055	active site
1088720004056	motif 3; other site
1088720004057	aspartate aminotransferase; Provisional; Region: PRK05764
1088720004058	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1088720004059	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1088720004060	homodimer interface [polypeptide binding]; other site
1088720004061	catalytic residue [active]
1088720004062	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5353
1088720004063	DnaQ family exonuclease/DinG family helicase, putative; Region: dinG_rel; TIGR01407
1088720004064	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1088720004065	active site
1088720004066	catalytic site [active]
1088720004067	substrate binding site [chemical binding]; other site
1088720004068	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1088720004069	helicase-exonuclease AddAB, AddA subunit, Firmicutes type; Region: addA_Gpos; TIGR02785
1088720004070	DEAD/DEAH box helicase; Region: DEAD; pfam00270
1088720004071	ATP binding site [chemical binding]; other site
1088720004072	Family description; Region: UvrD_C_2; pfam13538
1088720004073	helicase-exonuclease AddAB, AddB subunit; Region: addB_Gpos; TIGR02773
1088720004074	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
1088720004075	Mevalonate kinase [Lipid metabolism]; Region: ERG12; COG1577
1088720004076	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1088720004077	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1088720004078	diphosphomevalonate decarboxylase; Region: PLN02407
1088720004079	diphosphomevalonate decarboxylase; Region: mevDPdecarb; TIGR01240
1088720004080	isopentenyl pyrophosphate isomerase; Provisional; Region: PRK05437
1088720004081	Isopentenyl-diphosphate:dimethylallyl diphosphate isomerase type 2 (IDI-2) FMN-binding domain. Two types of IDIs have been characterized at present. The long known IDI-1 is only dependent on divalent metals for activity, whereas IDI-2 requires a metal; Region: IDI-2_FMN; cd02811
1088720004082	homotetramer interface [polypeptide binding]; other site
1088720004083	FMN binding site [chemical binding]; other site
1088720004084	homodimer contacts [polypeptide binding]; other site
1088720004085	putative active site [active]
1088720004086	putative substrate binding site [chemical binding]; other site
1088720004087	tRNA and rRNA cytosine-C5-methylases [Translation, ribosomal structure and biogenesis]; Region: Sun; COG0144
1088720004088	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1088720004089	S-adenosylmethionine binding site [chemical binding]; other site
1088720004090	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
1088720004091	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
1088720004092	4-oxalocrotonate tautomerase; Provisional; Region: PRK02220
1088720004093	active site 1 [active]
1088720004094	dimer interface [polypeptide binding]; other site
1088720004095	hexamer interface [polypeptide binding]; other site
1088720004096	active site 2 [active]
1088720004097	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1088720004098	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1088720004099	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720004100	Walker A/P-loop; other site
1088720004101	ATP binding site [chemical binding]; other site
1088720004102	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1088720004103	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720004104	Walker A/P-loop; other site
1088720004105	ATP binding site [chemical binding]; other site
1088720004106	Q-loop/lid; other site
1088720004107	ABC transporter signature motif; other site
1088720004108	Walker B; other site
1088720004109	D-loop; other site
1088720004110	H-loop/switch region; other site
1088720004111	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1088720004112	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
1088720004113	Predicted SAM-dependent methyltransferase [General function prediction only]; Region: COG2384
1088720004114	Family of unknown function (DUF633); Region: DUF633; pfam04816
1088720004115	RNA polymerase sigma factor RpoD; Validated; Region: PRK09210
1088720004116	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1088720004117	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1088720004118	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1088720004119	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1088720004120	DNA binding residues [nucleotide binding]
1088720004121	DNA primase; Validated; Region: dnaG; PRK05667
1088720004122	CHC2 zinc finger; Region: zf-CHC2; pfam01807
1088720004123	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1088720004124	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1088720004125	active site
1088720004126	metal binding site [ion binding]; metal-binding site
1088720004127	interdomain interaction site; other site
1088720004128	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
1088720004129	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
1088720004130	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1088720004131	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
1088720004132	dimer interface [polypeptide binding]; other site
1088720004133	motif 1; other site
1088720004134	active site
1088720004135	motif 2; other site
1088720004136	motif 3; other site
1088720004137	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1088720004138	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1088720004139	ABC-2 family transporter protein; Region: ABC2_membrane_5; pfam13346
1088720004140	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1088720004141	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1088720004142	Walker A/P-loop; other site
1088720004143	ATP binding site [chemical binding]; other site
1088720004144	Q-loop/lid; other site
1088720004145	ABC transporter signature motif; other site
1088720004146	Walker B; other site
1088720004147	D-loop; other site
1088720004148	H-loop/switch region; other site
1088720004149	Recombination protein O N terminal; Region: RecO_N; pfam11967
1088720004150	DNA repair protein RecO; Region: reco; TIGR00613
1088720004151	Recombination protein O C terminal; Region: RecO_C; pfam02565
1088720004152	GTPase Era; Reviewed; Region: era; PRK00089
1088720004153	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
1088720004154	G1 box; other site
1088720004155	GTP/Mg2+ binding site [chemical binding]; other site
1088720004156	Switch I region; other site
1088720004157	G2 box; other site
1088720004158	Switch II region; other site
1088720004159	G3 box; other site
1088720004160	G4 box; other site
1088720004161	G5 box; other site
1088720004162	KH domain; Region: KH_2; pfam07650
1088720004163	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1088720004164	active site
1088720004165	catalytic motif [active]
1088720004166	Zn binding site [ion binding]; other site
1088720004167	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
1088720004168	metal-binding heat shock protein; Provisional; Region: PRK00016
1088720004169	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1088720004170	PhoH-like protein; Region: PhoH; pfam02562
1088720004171	Yqey-like protein; Region: YqeY; pfam09424
1088720004172	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
1088720004173	Kinase/pyrophosphorylase; Region: Kinase-PPPase; pfam03618
1088720004174	endonuclease IV; Provisional; Region: PRK01060
1088720004175	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1088720004176	AP (apurinic/apyrimidinic) site pocket; other site
1088720004177	DNA interaction; other site
1088720004178	Metal-binding active site; metal-binding site
1088720004179	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1088720004180	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1088720004181	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1088720004182	methionine sulfoxide reductase B; Provisional; Region: PRK00222
1088720004183	SelR domain; Region: SelR; pfam01641
1088720004184	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1088720004185	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1088720004186	dimer interface [polypeptide binding]; other site
1088720004187	anticodon binding site; other site
1088720004188	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1088720004189	homodimer interface [polypeptide binding]; other site
1088720004190	motif 1; other site
1088720004191	active site
1088720004192	motif 2; other site
1088720004193	GAD domain; Region: GAD; pfam02938
1088720004194	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1088720004195	motif 3; other site
1088720004196	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
1088720004197	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1088720004198	dimer interface [polypeptide binding]; other site
1088720004199	motif 1; other site
1088720004200	active site
1088720004201	motif 2; other site
1088720004202	motif 3; other site
1088720004203	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1088720004204	anticodon binding site; other site
1088720004205	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1088720004206	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720004207	Walker A/P-loop; other site
1088720004208	ATP binding site [chemical binding]; other site
1088720004209	Q-loop/lid; other site
1088720004210	ABC transporter signature motif; other site
1088720004211	Walker B; other site
1088720004212	D-loop; other site
1088720004213	H-loop/switch region; other site
1088720004214	HIT family: HIT (Histidine triad) proteins, named for a motif related to the sequence HxHxH/Qxx (x, a hydrophobic amino acid), are a superfamily of nucleotide hydrolases and transferases, which act on the alpha-phosphate of ribonucleotides. On the basis...; Region: HIT_like; cl00228
1088720004215	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3807
1088720004216	Bacterial SH3 domain; Region: SH3_3; pfam08239
1088720004217	Bacterial SH3 domain; Region: SH3_3; pfam08239
1088720004218	Bacterial SH3 domain; Region: SH3_3; pfam08239
1088720004219	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1088720004220	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1088720004221	active site
1088720004222	metal binding site [ion binding]; metal-binding site
1088720004223	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
1088720004224	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1088720004225	motif II; other site
1088720004226	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
1088720004227	putative active site [active]
1088720004228	dimerization interface [polypeptide binding]; other site
1088720004229	putative tRNAtyr binding site [nucleotide binding]; other site
1088720004230	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1088720004231	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1088720004232	Zn2+ binding site [ion binding]; other site
1088720004233	Mg2+ binding site [ion binding]; other site
1088720004234	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1088720004235	synthetase active site [active]
1088720004236	NTP binding site [chemical binding]; other site
1088720004237	metal binding site [ion binding]; metal-binding site
1088720004238	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1088720004239	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1088720004240	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
1088720004241	RNA methyltransferase, RsmE family; Region: TIGR00046
1088720004242	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
1088720004243	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1088720004244	S-adenosylmethionine binding site [chemical binding]; other site
1088720004245	Protein of unknown function (DUF3013); Region: DUF3013; pfam11217
1088720004246	Alkyladenine DNA glycosylase catalyzes the first step in base excision repair; Region: AAG; cd00540
1088720004247	active site
1088720004248	DNA binding site [nucleotide binding]
1088720004249	Protein of unknown function (DUF1093); Region: DUF1093; cl02185
1088720004250	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1088720004251	Flavodoxin-like fold; Region: Flavodoxin_2; pfam02525
1088720004252	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1088720004253	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1088720004254	WHG domain; Region: WHG; pfam13305
1088720004255	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1088720004256	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1088720004257	accessory Sec system glycosylation protein GtfA; Region: TIGR02918
1088720004258	This family is most closely related to the GT1 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding.  In...; Region: GT1_gtfA_like; cd04949
1088720004259	Domain of unknown function (DUF1975); Region: DUF1975; pfam09318
1088720004260	This family is most closely related to the GT1 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding.  In...; Region: GT1_gtfA_like; cd04949
1088720004261	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1088720004262	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
1088720004263	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
1088720004264	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
1088720004265	SCP: SCP-like extracellular protein domain, found in eukaryotes and prokaryotes. This family includes plant pathogenesis-related protein 1 (PR-1), which accumulates after infections with pathogens, and may act as an anti-fungal agent or be involved in...; Region: SCP; cl00133
1088720004266	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
1088720004267	KxYKxGKxW signal peptide; Region: KxYKxGKxW; TIGR03715
1088720004268	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
1088720004269	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
1088720004270	KxYKxGKxW signal peptide; Region: KxYKxGKxW; TIGR03715
1088720004271	surface protein repeat Ser-Ala-175; Region: SerAla_Lrha_rpt; TIGR04319
1088720004272	N-formylglutamate amidohydrolase; Region: FGase; pfam05013
1088720004273	Staphylococcal protein of unknown function (DUF960); Region: DUF960; pfam06124
1088720004274	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
1088720004275	putative deacylase active site [active]
1088720004276	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1088720004277	active site
1088720004278	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
1088720004279	DHH family; Region: DHH; pfam01368
1088720004280	Single-strand DNA-specific exonuclease, C terminal domain; Region: ssDNA-exonuc_C; cl11538
1088720004281	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
1088720004282	GTP-binding protein LepA; Provisional; Region: PRK05433
1088720004283	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1088720004284	G1 box; other site
1088720004285	putative GEF interaction site [polypeptide binding]; other site
1088720004286	GTP/Mg2+ binding site [chemical binding]; other site
1088720004287	Switch I region; other site
1088720004288	G2 box; other site
1088720004289	G3 box; other site
1088720004290	Switch II region; other site
1088720004291	G4 box; other site
1088720004292	G5 box; other site
1088720004293	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
1088720004294	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1088720004295	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1088720004296	chaperone protein DnaJ; Provisional; Region: PRK14276
1088720004297	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1088720004298	HSP70 interaction site [polypeptide binding]; other site
1088720004299	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
1088720004300	substrate binding site [polypeptide binding]; other site
1088720004301	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1088720004302	Zn binding sites [ion binding]; other site
1088720004303	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1088720004304	dimer interface [polypeptide binding]; other site
1088720004305	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1088720004306	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
1088720004307	nucleotide binding site [chemical binding]; other site
1088720004308	NEF interaction site [polypeptide binding]; other site
1088720004309	SBD interface [polypeptide binding]; other site
1088720004310	GrpE; Region: GrpE; pfam01025
1088720004311	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1088720004312	dimer interface [polypeptide binding]; other site
1088720004313	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1088720004314	heat-inducible transcription repressor; Provisional; Region: hrcA; PRK00082
1088720004315	HTH domain; Region: HTH_11; pfam08279
1088720004316	coproporphyrinogen III oxidase; Provisional; Region: PRK08599
1088720004317	HemN C-terminal domain; Region: HemN_C; pfam06969
1088720004318	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
1088720004319	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
1088720004320	active site
1088720004321	Riboflavin kinase; Region: Flavokinase; smart00904
1088720004322	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK02484
1088720004323	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
1088720004324	RNA binding site [nucleotide binding]; other site
1088720004325	active site
1088720004326	integral membrane protein, YkoY family; Region: R_switched_YkoY; TIGR03716
1088720004327	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
1088720004328	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1088720004329	translation initiation factor IF-2; Region: IF-2; TIGR00487
1088720004330	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1088720004331	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1088720004332	G1 box; other site
1088720004333	putative GEF interaction site [polypeptide binding]; other site
1088720004334	GTP/Mg2+ binding site [chemical binding]; other site
1088720004335	Switch I region; other site
1088720004336	G2 box; other site
1088720004337	G3 box; other site
1088720004338	Switch II region; other site
1088720004339	G4 box; other site
1088720004340	G5 box; other site
1088720004341	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1088720004342	Translation-initiation factor 2; Region: IF-2; pfam11987
1088720004343	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1088720004344	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; Region: Ribosomal_L7Ae; cl00600
1088720004345	Ylxr homologs; group of conserved hypothetical bacterial proteins of unknown function; structure revealed putative RNA binding cleft; proteins are encoded by an operon that includes other proteins involved in transcription and/or translation; Region: YlxR; cd00279
1088720004346	putative RNA binding cleft [nucleotide binding]; other site
1088720004347	transcription elongation factor NusA; Provisional; Region: nusA; PRK12327
1088720004348	NusA N-terminal domain; Region: NusA_N; pfam08529
1088720004349	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
1088720004350	RNA binding site [nucleotide binding]; other site
1088720004351	homodimer interface [polypeptide binding]; other site
1088720004352	NusA-like KH domain; Region: KH_5; pfam13184
1088720004353	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1088720004354	G-X-X-G motif; other site
1088720004355	ribosome maturation protein RimP; Reviewed; Region: PRK00092
1088720004356	Sm and related proteins; Region: Sm_like; cl00259
1088720004357	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
1088720004358	putative oligomer interface [polypeptide binding]; other site
1088720004359	putative RNA binding site [nucleotide binding]; other site
1088720004360	DNA polymerase III PolC; Validated; Region: polC; PRK00448
1088720004361	DNA polymerase III polC-type N-terminus; Region: DNA_pol3_alph_N; pfam11490
1088720004362	polC_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold nucleic acid binding domain of Bacillus subtilis type C replicative DNA polymerase III alpha subunit (polC). Replication in B. subtilis and Staphylococcus aureus requires two...; Region: polC_OBF; cd04484
1088720004363	generic binding surface II; other site
1088720004364	generic binding surface I; other site
1088720004365	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
1088720004366	active site
1088720004367	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1088720004368	active site
1088720004369	catalytic site [active]
1088720004370	substrate binding site [chemical binding]; other site
1088720004371	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III at PolC gene; Region: PHP_PolIIIA_POLC; cd07435
1088720004372	prolyl-tRNA synthetase; Provisional; Region: PRK09194
1088720004373	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
1088720004374	dimer interface [polypeptide binding]; other site
1088720004375	motif 1; other site
1088720004376	active site
1088720004377	motif 2; other site
1088720004378	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
1088720004379	putative deacylase active site [active]
1088720004380	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1088720004381	active site
1088720004382	motif 3; other site
1088720004383	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
1088720004384	anticodon binding site; other site
1088720004385	RIP metalloprotease RseP; Region: TIGR00054
1088720004386	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1088720004387	active site
1088720004388	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
1088720004389	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1088720004390	protein binding site [polypeptide binding]; other site
1088720004391	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
1088720004392	putative substrate binding region [chemical binding]; other site
1088720004393	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1088720004394	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
1088720004395	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
1088720004396	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
1088720004397	catalytic residue [active]
1088720004398	putative FPP diphosphate  binding site; other site
1088720004399	putative FPP binding hydrophobic cleft; other site
1088720004400	dimer interface [polypeptide binding]; other site
1088720004401	putative IPP diphosphate binding site; other site
1088720004402	ribosome recycling factor; Reviewed; Region: frr; PRK00083
1088720004403	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1088720004404	hinge region; other site
1088720004405	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1088720004406	putative nucleotide binding site [chemical binding]; other site
1088720004407	uridine monophosphate binding site [chemical binding]; other site
1088720004408	homohexameric interface [polypeptide binding]; other site
1088720004409	elongation factor Ts; Provisional; Region: tsf; PRK09377
1088720004410	UBA/TS-N domain; Region: UBA; pfam00627
1088720004411	Elongation factor TS; Region: EF_TS; pfam00889
1088720004412	Elongation factor TS; Region: EF_TS; pfam00889
1088720004413	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1088720004414	rRNA interaction site [nucleotide binding]; other site
1088720004415	S8 interaction site; other site
1088720004416	putative laminin-1 binding site; other site
1088720004417	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
1088720004418	GIY-YIG motif/motif A; other site
1088720004419	putative active site [active]
1088720004420	putative metal binding site [ion binding]; other site
1088720004421	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
1088720004422	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1088720004423	S-adenosylmethionine binding site [chemical binding]; other site
1088720004424	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1088720004425	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1088720004426	putative acyl-acceptor binding pocket; other site
1088720004427	amino acid transporter; Region: 2A0306; TIGR00909
1088720004428	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
1088720004429	Protein of unknown function (DUF1003); Region: DUF1003; pfam06210
1088720004430	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1088720004431	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1088720004432	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
1088720004433	Walker A/P-loop; other site
1088720004434	ATP binding site [chemical binding]; other site
1088720004435	Q-loop/lid; other site
1088720004436	ABC transporter signature motif; other site
1088720004437	Walker B; other site
1088720004438	D-loop; other site
1088720004439	H-loop/switch region; other site
1088720004440	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
1088720004441	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1088720004442	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720004443	Walker A/P-loop; other site
1088720004444	ATP binding site [chemical binding]; other site
1088720004445	Q-loop/lid; other site
1088720004446	ABC transporter signature motif; other site
1088720004447	Walker B; other site
1088720004448	D-loop; other site
1088720004449	H-loop/switch region; other site
1088720004450	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3763
1088720004451	Bacterial protein of unknown function (DUF896); Region: DUF896; pfam05979
1088720004452	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1088720004453	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
1088720004454	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
1088720004455	RimM N-terminal domain; Region: RimM; pfam01782
1088720004456	PRC-barrel domain; Region: PRC; pfam05239
1088720004457	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
1088720004458	KH domain; Region: KH_4; pfam13083
1088720004459	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
1088720004460	signal recognition particle protein; Provisional; Region: PRK10867
1088720004461	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
1088720004462	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1088720004463	P loop; other site
1088720004464	GTP binding site [chemical binding]; other site
1088720004465	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1088720004466	Putative helix-turn-helix protein, YlxM / p13 like; Region: UPF0122; pfam04297
1088720004467	putative DNA-binding protein; Validated; Region: PRK00118
1088720004468	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
1088720004469	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
1088720004470	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1088720004471	P loop; other site
1088720004472	GTP binding site [chemical binding]; other site
1088720004473	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
1088720004474	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
1088720004475	Walker A/P-loop; other site
1088720004476	ATP binding site [chemical binding]; other site
1088720004477	Q-loop/lid; other site
1088720004478	SMC proteins Flexible Hinge Domain; Region: SMC_hinge; smart00968
1088720004479	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
1088720004480	ABC transporter signature motif; other site
1088720004481	Walker B; other site
1088720004482	D-loop; other site
1088720004483	H-loop/switch region; other site
1088720004484	ribonuclease III, bacterial; Region: RNaseIII; TIGR02191
1088720004485	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1088720004486	dimerization interface [polypeptide binding]; other site
1088720004487	active site
1088720004488	metal binding site [ion binding]; metal-binding site
1088720004489	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1088720004490	The substrate binding component of an ABC-type lactococcal OppA-like transport system contains; Region: PBP2_Lactococcal_OppA_like; cd08510
1088720004491	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
1088720004492	peptide binding site [polypeptide binding]; other site
1088720004493	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1088720004494	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1088720004495	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1088720004496	dimer interface [polypeptide binding]; other site
1088720004497	conserved gate region; other site
1088720004498	putative PBP binding loops; other site
1088720004499	ABC-ATPase subunit interface; other site
1088720004500	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1088720004501	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1088720004502	dimer interface [polypeptide binding]; other site
1088720004503	conserved gate region; other site
1088720004504	putative PBP binding loops; other site
1088720004505	ABC-ATPase subunit interface; other site
1088720004506	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1088720004507	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1088720004508	Walker A/P-loop; other site
1088720004509	ATP binding site [chemical binding]; other site
1088720004510	Q-loop/lid; other site
1088720004511	ABC transporter signature motif; other site
1088720004512	Walker B; other site
1088720004513	D-loop; other site
1088720004514	H-loop/switch region; other site
1088720004515	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1088720004516	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1088720004517	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1088720004518	Walker A/P-loop; other site
1088720004519	ATP binding site [chemical binding]; other site
1088720004520	Q-loop/lid; other site
1088720004521	ABC transporter signature motif; other site
1088720004522	Walker B; other site
1088720004523	D-loop; other site
1088720004524	H-loop/switch region; other site
1088720004525	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1088720004526	acyl carrier protein; Provisional; Region: acpP; PRK00982
1088720004527	putative phosphate acyltransferase; Provisional; Region: PRK05331
1088720004528	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
1088720004529	Y-family of DNA polymerases; Region: PolY; cl12025
1088720004530	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
1088720004531	generic binding surface II; other site
1088720004532	ssDNA binding site; other site
1088720004533	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1088720004534	ATP binding site [chemical binding]; other site
1088720004535	putative Mg++ binding site [ion binding]; other site
1088720004536	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1088720004537	nucleotide binding region [chemical binding]; other site
1088720004538	ATP-binding site [chemical binding]; other site
1088720004539	DAK2 domain fusion protein YloV; Region: YloV; TIGR03599
1088720004540	DAK2 domain; Region: Dak2; pfam02734
1088720004541	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1302
1088720004542	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
1088720004543	Thiamine pyrophosphokinase; Region: TPK; cd07995
1088720004544	thiamine pyrophosphokinase; Region: thi_PPkinase; TIGR01378
1088720004545	active site
1088720004546	dimerization interface [polypeptide binding]; other site
1088720004547	thiamine binding site [chemical binding]; other site
1088720004548	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1088720004549	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1088720004550	substrate binding site [chemical binding]; other site
1088720004551	hexamer interface [polypeptide binding]; other site
1088720004552	metal binding site [ion binding]; metal-binding site
1088720004553	GTPase RsgA; Reviewed; Region: PRK00098
1088720004554	S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466
1088720004555	RNA binding site [nucleotide binding]; other site
1088720004556	homodimer interface [polypeptide binding]; other site
1088720004557	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
1088720004558	GTPase/Zn-binding domain interface [polypeptide binding]; other site
1088720004559	GTP/Mg2+ binding site [chemical binding]; other site
1088720004560	G4 box; other site
1088720004561	G5 box; other site
1088720004562	G1 box; other site
1088720004563	Switch I region; other site
1088720004564	G2 box; other site
1088720004565	G3 box; other site
1088720004566	Switch II region; other site
1088720004567	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
1088720004568	Catalytic domain of Protein Kinases; Region: PKc; cd00180
1088720004569	active site
1088720004570	ATP binding site [chemical binding]; other site
1088720004571	substrate binding site [chemical binding]; other site
1088720004572	activation loop (A-loop); other site
1088720004573	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2815
1088720004574	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
1088720004575	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
1088720004576	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
1088720004577	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
1088720004578	active site
1088720004579	16S rRNA methyltransferase B; Provisional; Region: PRK14902
1088720004580	NusB family; Region: NusB; pfam01029
1088720004581	putative RNA binding site [nucleotide binding]; other site
1088720004582	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1088720004583	S-adenosylmethionine binding site [chemical binding]; other site
1088720004584	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
1088720004585	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
1088720004586	putative active site [active]
1088720004587	substrate binding site [chemical binding]; other site
1088720004588	putative cosubstrate binding site; other site
1088720004589	catalytic site [active]
1088720004590	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1088720004591	substrate binding site [chemical binding]; other site
1088720004592	Primosomal protein N' (replication factor Y) - superfamily II helicase [DNA replication, recombination, and repair]; Region: PriA; COG1198
1088720004593	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1088720004594	ATP binding site [chemical binding]; other site
1088720004595	putative Mg++ binding site [ion binding]; other site
1088720004596	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1088720004597	nucleotide binding region [chemical binding]; other site
1088720004598	ATP-binding site [chemical binding]; other site
1088720004599	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
1088720004600	Flavoprotein; Region: Flavoprotein; pfam02441
1088720004601	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
1088720004602	DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392
1088720004603	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
1088720004604	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1088720004605	catalytic site [active]
1088720004606	G-X2-G-X-G-K; other site
1088720004607	Hypothetical patatin similar to Z1214 protein of Escherichia coli; Region: Pat_hypo_Ecoli_Z1214_like; cd07209
1088720004608	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
1088720004609	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1088720004610	Walker A/P-loop; other site
1088720004611	ATP binding site [chemical binding]; other site
1088720004612	Q-loop/lid; other site
1088720004613	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1088720004614	ABC transporter signature motif; other site
1088720004615	Walker B; other site
1088720004616	D-loop; other site
1088720004617	H-loop/switch region; other site
1088720004618	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
1088720004619	arginine repressor; Provisional; Region: PRK04280
1088720004620	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
1088720004621	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
1088720004622	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1088720004623	RNA binding surface [nucleotide binding]; other site
1088720004624	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1088720004625	S-adenosylmethionine binding site [chemical binding]; other site
1088720004626	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1088720004627	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1088720004628	substrate binding pocket [chemical binding]; other site
1088720004629	chain length determination region; other site
1088720004630	substrate-Mg2+ binding site; other site
1088720004631	catalytic residues [active]
1088720004632	aspartate-rich region 1; other site
1088720004633	active site lid residues [active]
1088720004634	aspartate-rich region 2; other site
1088720004635	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
1088720004636	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
1088720004637	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
1088720004638	generic binding surface II; other site
1088720004639	generic binding surface I; other site
1088720004640	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14169
1088720004641	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1088720004642	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1088720004643	homodimer interface [polypeptide binding]; other site
1088720004644	NADP binding site [chemical binding]; other site
1088720004645	substrate binding site [chemical binding]; other site
1088720004646	transcription antitermination protein NusB; Reviewed; Region: nusB; PRK00202
1088720004647	Asp23 family; Region: Asp23; pfam03780
1088720004648	elongation factor P; Validated; Region: PRK00529
1088720004649	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1088720004650	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1088720004651	RNA binding site [nucleotide binding]; other site
1088720004652	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1088720004653	RNA binding site [nucleotide binding]; other site
1088720004654	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
1088720004655	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1088720004656	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
1088720004657	active site
1088720004658	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1088720004659	Protein of unknown function (DUF464); Region: DUF464; pfam04327
1088720004660	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
1088720004661	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1088720004662	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1088720004663	Walker A/P-loop; other site
1088720004664	ATP binding site [chemical binding]; other site
1088720004665	Q-loop/lid; other site
1088720004666	ABC transporter signature motif; other site
1088720004667	Walker B; other site
1088720004668	D-loop; other site
1088720004669	H-loop/switch region; other site
1088720004670	x-prolyl-dipeptidyl aminopeptidase; Provisional; Region: PRK05371
1088720004671	X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal; Region: PepX_N; pfam09168
1088720004672	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; pfam08530
1088720004673	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
1088720004674	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
1088720004675	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1088720004676	Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators; Region: HTH_GlnR-like; cd01105
1088720004677	DNA binding residues [nucleotide binding]
1088720004678	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1088720004679	putative dimer interface [polypeptide binding]; other site
1088720004680	putative ornithine decarboxylase; Region: lacto_ODC_hypo; TIGR04318
1088720004681	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1088720004682	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1088720004683	catalytic residue [active]
1088720004684	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1088720004685	Aluminium resistance protein; Region: Alum_res; pfam06838
1088720004686	Cystathionine beta-lyase family protein involved in aluminum resistance [Inorganic ion transport and metabolism]; Region: COG4100
1088720004687	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
1088720004688	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1088720004689	Protein of unknown function (DUF3042); Region: DUF3042; pfam11240
1088720004690	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1088720004691	active site residue [active]
1088720004692	ROK family protein (putative glucokinase); Region: ROK_glcA_fam; TIGR00744
1088720004693	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1088720004694	nucleotide binding site [chemical binding]; other site
1088720004695	Bacterial protein of unknown function (DUF910); Region: DUF910; pfam06014
1088720004696	Rhomboid family; Region: Rhomboid; pfam01694
1088720004697	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
1088720004698	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1088720004699	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1088720004700	Bacterial membrane protein YfhO; Region: YfhO; pfam09586
1088720004701	Iron-sulphur cluster biosynthesis; Region: Fe-S_biosyn; cl00400
1088720004702	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1088720004703	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1088720004704	active site
1088720004705	phosphorylation site [posttranslational modification]
1088720004706	intermolecular recognition site; other site
1088720004707	dimerization interface [polypeptide binding]; other site
1088720004708	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1088720004709	DNA binding residues [nucleotide binding]
1088720004710	dimerization interface [polypeptide binding]; other site
1088720004711	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1088720004712	Histidine kinase; Region: HisKA_3; pfam07730
1088720004713	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1088720004714	ATP binding site [chemical binding]; other site
1088720004715	Mg2+ binding site [ion binding]; other site
1088720004716	G-X-G motif; other site
1088720004717	Predicted membrane protein [Function unknown]; Region: COG4758
1088720004718	Cell wall-active antibiotics response protein (DUF2154); Region: DUF2154; pfam09922
1088720004719	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1088720004720	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1088720004721	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1088720004722	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
1088720004723	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
1088720004724	ATP-binding site [chemical binding]; other site
1088720004725	Sugar specificity; other site
1088720004726	Pyrimidine base specificity; other site
1088720004727	YceG-like family; Region: YceG; pfam02618
1088720004728	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
1088720004729	dimerization interface [polypeptide binding]; other site
1088720004730	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
1088720004731	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1088720004732	putative tRNA-binding site [nucleotide binding]; other site
1088720004733	B3/4 domain; Region: B3_4; pfam03483
1088720004734	tRNA synthetase B5 domain; Region: B5; smart00874
1088720004735	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
1088720004736	dimer interface [polypeptide binding]; other site
1088720004737	motif 1; other site
1088720004738	motif 3; other site
1088720004739	motif 2; other site
1088720004740	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
1088720004741	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1088720004742	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1088720004743	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1088720004744	dimer interface [polypeptide binding]; other site
1088720004745	motif 1; other site
1088720004746	active site
1088720004747	motif 2; other site
1088720004748	motif 3; other site
1088720004749	Predicted transcriptional regulators [Transcription]; Region: COG1733
1088720004750	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1088720004751	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1088720004752	Zn2+ binding site [ion binding]; other site
1088720004753	Mg2+ binding site [ion binding]; other site
1088720004754	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
1088720004755	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
1088720004756	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1088720004757	Acylphosphatase; Region: Acylphosphatase; pfam00708
1088720004758	OxaA-like protein precursor; Provisional; Region: PRK02463
1088720004759	60Kd inner membrane protein; Region: 60KD_IMP; cl00489
1088720004760	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1088720004761	HAMP domain; Region: HAMP; pfam00672
1088720004762	dimerization interface [polypeptide binding]; other site
1088720004763	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1088720004764	dimer interface [polypeptide binding]; other site
1088720004765	phosphorylation site [posttranslational modification]
1088720004766	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1088720004767	ATP binding site [chemical binding]; other site
1088720004768	Mg2+ binding site [ion binding]; other site
1088720004769	G-X-G motif; other site
1088720004770	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1088720004771	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1088720004772	active site
1088720004773	phosphorylation site [posttranslational modification]
1088720004774	intermolecular recognition site; other site
1088720004775	dimerization interface [polypeptide binding]; other site
1088720004776	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1088720004777	DNA binding site [nucleotide binding]
1088720004778	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1088720004779	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
1088720004780	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
1088720004781	Uncharacterized ACR, COG1399; Region: DUF177; cl00616
1088720004782	hypothetical protein; Provisional; Region: PRK13670
1088720004783	HIGH Nucleotidyl Transferase; Region: HIGH_NTase1; cl17673
1088720004784	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1088720004785	S-adenosylmethionine binding site [chemical binding]; other site
1088720004786	Uncharacterized homolog of plant Iojap protein [Function unknown]; Region: COG0799
1088720004787	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1088720004788	Zn2+ binding site [ion binding]; other site
1088720004789	Mg2+ binding site [ion binding]; other site
1088720004790	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
1088720004791	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
1088720004792	active site
1088720004793	(T/H)XGH motif; other site
1088720004794	Predicted RNA-binding protein containing KH domain, possibly ribosomal protein [Translation, ribosomal structure and biogenesis]; Region: COG1534
1088720004795	GTPase YqeH; Provisional; Region: PRK13796
1088720004796	Circularly permuted YqeH GTPase; Region: YqeH; cd01855
1088720004797	GTP/Mg2+ binding site [chemical binding]; other site
1088720004798	G4 box; other site
1088720004799	G5 box; other site
1088720004800	G1 box; other site
1088720004801	Switch I region; other site
1088720004802	G2 box; other site
1088720004803	G3 box; other site
1088720004804	Switch II region; other site
1088720004805	Predicted hydrolase of the HAD superfamily [General function prediction only]; Region: COG2179
1088720004806	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1088720004807	active site
1088720004808	motif I; other site
1088720004809	motif II; other site
1088720004810	N-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_N_like; cd08346
1088720004811	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1088720004812	Zn binding site [ion binding]; other site
1088720004813	C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_C_like; cd08347
1088720004814	Zn binding site [ion binding]; other site
1088720004815	N-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_N_like; cd08346
1088720004816	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1088720004817	Zn binding site [ion binding]; other site
1088720004818	C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_C_like; cd08347
1088720004819	Zn binding site [ion binding]; other site
1088720004820	putative hydrolase; Provisional; Region: PRK11460
1088720004821	Predicted esterase [General function prediction only]; Region: COG0400
1088720004822	alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases; Region: MDR_like_2; cd05289
1088720004823	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
1088720004824	putative NAD(P) binding site [chemical binding]; other site
1088720004825	Possible lysine decarboxylase; Region: Lysine_decarbox; cl00695
1088720004826	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1088720004827	23S rRNA binding site [nucleotide binding]; other site
1088720004828	L21 binding site [polypeptide binding]; other site
1088720004829	L13 binding site [polypeptide binding]; other site
1088720004830	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
1088720004831	translation initiation factor IF-3; Region: infC; TIGR00168
1088720004832	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
1088720004833	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1088720004834	stage V sporulation protein K; Region: spore_V_K; TIGR02881
1088720004835	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1088720004836	Walker A motif; other site
1088720004837	ATP binding site [chemical binding]; other site
1088720004838	Walker B motif; other site
1088720004839	arginine finger; other site
1088720004840	stage V sporulation protein K; Region: spore_V_K; TIGR02881
1088720004841	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1088720004842	Walker A motif; other site
1088720004843	ATP binding site [chemical binding]; other site
1088720004844	Walker B motif; other site
1088720004845	arginine finger; other site
1088720004846	WYL domain; Region: WYL; pfam13280
1088720004847	SseB protein; Region: SseB; cl06279
1088720004848	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
1088720004849	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
1088720004850	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1088720004851	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1088720004852	active site
1088720004853	dimer interface [polypeptide binding]; other site
1088720004854	motif 1; other site
1088720004855	motif 2; other site
1088720004856	motif 3; other site
1088720004857	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1088720004858	anticodon binding site; other site
1088720004859	primosomal protein DnaI; Reviewed; Region: PRK08939
1088720004860	Primosomal protein DnaI N-terminus; Region: DnaI_N; pfam07319
1088720004861	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1088720004862	Walker A motif; other site
1088720004863	ATP binding site [chemical binding]; other site
1088720004864	Walker B motif; other site
1088720004865	Replication initiation/membrane attachment protein [DNA replication, recombination, and repair]; Region: DnaB; COG3611
1088720004866	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
1088720004867	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
1088720004868	ATP cone domain; Region: ATP-cone; pfam03477
1088720004869	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
1088720004870	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1088720004871	CoA-binding site [chemical binding]; other site
1088720004872	ATP-binding [chemical binding]; other site
1088720004873	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
1088720004874	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
1088720004875	DNA binding site [nucleotide binding]
1088720004876	catalytic residue [active]
1088720004877	H2TH interface [polypeptide binding]; other site
1088720004878	putative catalytic residues [active]
1088720004879	turnover-facilitating residue; other site
1088720004880	intercalation triad [nucleotide binding]; other site
1088720004881	8OG recognition residue [nucleotide binding]; other site
1088720004882	putative reading head residues; other site
1088720004883	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1088720004884	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1088720004885	DNA polymerase I; Provisional; Region: PRK05755
1088720004886	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1088720004887	active site
1088720004888	metal binding site 1 [ion binding]; metal-binding site
1088720004889	putative 5' ssDNA interaction site; other site
1088720004890	metal binding site 3; metal-binding site
1088720004891	metal binding site 2 [ion binding]; metal-binding site
1088720004892	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1088720004893	putative DNA binding site [nucleotide binding]; other site
1088720004894	putative metal binding site [ion binding]; other site
1088720004895	inactive DEDDy 3'-5' exonuclease domain of Bacillus stearothermophilus DNA polymerase I and similar family-A DNA polymerases; Region: DNA_polA_I_Bacillus_like_exo; cd06140
1088720004896	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
1088720004897	active site
1088720004898	DNA binding site [nucleotide binding]
1088720004899	catalytic site [active]
1088720004900	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1088720004901	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1088720004902	Bacterial protein of unknown function (DUF916); Region: DUF916; pfam06030
1088720004903	Protein of unknown function C-terminal (DUF3324); Region: DUF3324; pfam11797
1088720004904	WxL domain surface cell wall-binding; Region: WxL; pfam13731
1088720004905	Mga helix-turn-helix domain; Region: Mga; pfam05043
1088720004906	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
1088720004907	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1088720004908	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1088720004909	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1088720004910	This domain directs oriented DNA translocation and forms a winged helix structure; Region: Ftsk_gamma; smart00843
1088720004911	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1088720004912	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1088720004913	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1088720004914	putative tRNA-binding site [nucleotide binding]; other site
1088720004915	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1088720004916	catalytic residues [active]
1088720004917	Predicted small secreted protein [Function unknown]; Region: COG5584
1088720004918	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1088720004919	S-adenosylmethionine binding site [chemical binding]; other site
1088720004920	Thiamine kinase and related kinases [Coenzyme transport and metabolism]; Region: ycfN; COG0510
1088720004921	Phosphotransferase enzyme family; Region: APH; pfam01636
1088720004922	active site
1088720004923	substrate binding site [chemical binding]; other site
1088720004924	ATP binding site [chemical binding]; other site
1088720004925	Bacterial ABC transporter protein EcsB; Region: EcsB; pfam05975
1088720004926	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
1088720004927	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1088720004928	Walker A/P-loop; other site
1088720004929	ATP binding site [chemical binding]; other site
1088720004930	Q-loop/lid; other site
1088720004931	ABC transporter signature motif; other site
1088720004932	Walker B; other site
1088720004933	D-loop; other site
1088720004934	H-loop/switch region; other site
1088720004935	HINT (histidine triad nucleotide-binding protein) subgroup: Members of this CD belong to the superfamily of histidine triad hydrolases that act on alpha-phosphate of ribonucleotides. This subgroup includes members from all three forms of cellular life; Region: HINT_subgroup; cd01277
1088720004936	HIT family signature motif; other site
1088720004937	catalytic residue [active]
1088720004938	YtxH-like protein; Region: YtxH; pfam12732
1088720004939	peptidylprolyl isomerase; Provisional; Region: prsA; PRK04405
1088720004940	SurA N-terminal domain; Region: SurA_N_3; cl07813
1088720004941	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1088720004942	3'-5' exoribonuclease YhaM; Provisional; Region: PRK13480
1088720004943	YhaM_OBF_like: A subfamily of OB folds similar to that found in Bacillus subtilis YhaM and Staphylococcus aureus cmp-binding factor-1 (SaCBF1). Both these proteins are 3'-to-5'exoribonucleases. YhaM requires Mn2+ or Co2+ for activity and is...; Region: YhaM_OBF_like; cd04492
1088720004944	generic binding surface I; other site
1088720004945	generic binding surface II; other site
1088720004946	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1088720004947	Zn2+ binding site [ion binding]; other site
1088720004948	Mg2+ binding site [ion binding]; other site
1088720004949	Protein of unknown function (DUF964); Region: DUF964; cl01483
1088720004950	Transglycosylase; Region: Transgly; pfam00912
1088720004951	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
1088720004952	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1088720004953	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1088720004954	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1088720004955	active site
1088720004956	Arginine repressor [Transcription]; Region: ArgR; COG1438
1088720004957	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
1088720004958	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
1088720004959	arginyl-tRNA synthetase; Reviewed; Region: PRK12451
1088720004960	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
1088720004961	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
1088720004962	active site
1088720004963	HIGH motif; other site
1088720004964	KMSK motif region; other site
1088720004965	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
1088720004966	tRNA binding surface [nucleotide binding]; other site
1088720004967	anticodon binding site; other site
1088720004968	dihydroorotate dehydrogenase (subfamily 1) family protein; Region: pyrD_sub1_fam; TIGR01037
1088720004969	Dihydroorotate dehydrogenase (DHOD) class 1A FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine...; Region: DHOD_1A_like; cd04741
1088720004970	active site
1088720004971	FMN binding site [chemical binding]; other site
1088720004972	substrate binding site [chemical binding]; other site
1088720004973	catalytic residues [active]
1088720004974	homodimer interface [polypeptide binding]; other site
1088720004975	Membrane domain of glycerophosphoryl diester phosphodiesterase; Region: GPDPase_memb; pfam10110
1088720004976	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
1088720004977	Glycerophosphodiester phosphodiesterase domain of uncharacterized bacterial glycerophosphodiester phosphodiesterases; Region: GDPD_memb_like; cd08579
1088720004978	putative active site [active]
1088720004979	catalytic site [active]
1088720004980	putative metal binding site [ion binding]; other site
1088720004981	adaptor protein; Provisional; Region: PRK02315
1088720004982	Arsenate Reductase (ArsC) family, Spx subfamily; Spx is a unique RNA polymerase (RNAP)-binding protein present in bacilli and some mollicutes. It inhibits transcription by binding to the C-terminal domain of the alpha subunit of RNAP, disrupting complex...; Region: ArsC_Spx; cd03032
1088720004983	ArsC family; Region: ArsC; pfam03960
1088720004984	putative catalytic residues [active]
1088720004985	thiol/disulfide switch; other site
1088720004986	Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only]; Region: ElaC; COG1234
1088720004987	FtsX-like permease family; Region: FtsX; pfam02687
1088720004988	FtsX-like permease family; Region: FtsX; pfam02687
1088720004989	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1088720004990	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1088720004991	Walker A/P-loop; other site
1088720004992	ATP binding site [chemical binding]; other site
1088720004993	Q-loop/lid; other site
1088720004994	ABC transporter signature motif; other site
1088720004995	Walker B; other site
1088720004996	D-loop; other site
1088720004997	H-loop/switch region; other site
1088720004998	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1088720004999	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1088720005000	active site
1088720005001	phosphorylation site [posttranslational modification]
1088720005002	intermolecular recognition site; other site
1088720005003	dimerization interface [polypeptide binding]; other site
1088720005004	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1088720005005	DNA binding site [nucleotide binding]
1088720005006	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1088720005007	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
1088720005008	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1088720005009	ATP binding site [chemical binding]; other site
1088720005010	Mg2+ binding site [ion binding]; other site
1088720005011	G-X-G motif; other site
1088720005012	anaerobic ribonucleotide reductase-activating protein; Provisional; Region: nrdG; cl15804
1088720005013	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
1088720005014	copper-(or silver)-translocating P-type ATPase; Region: ATPase-IB1_Cu; TIGR01511
1088720005015	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1088720005016	copper transport repressor, CopY/TcrY family; Region: CopY_TcrY; TIGR02698
1088720005017	Penicillinase repressor; Region: Pencillinase_R; pfam03965
1088720005018	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
1088720005019	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
1088720005020	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1088720005021	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
1088720005022	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
1088720005023	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
1088720005024	purine monophosphate binding site [chemical binding]; other site
1088720005025	dimer interface [polypeptide binding]; other site
1088720005026	putative catalytic residues [active]
1088720005027	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
1088720005028	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
1088720005029	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
1088720005030	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
1088720005031	active site
1088720005032	substrate binding site [chemical binding]; other site
1088720005033	cosubstrate binding site; other site
1088720005034	catalytic site [active]
1088720005035	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
1088720005036	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
1088720005037	dimerization interface [polypeptide binding]; other site
1088720005038	putative ATP binding site [chemical binding]; other site
1088720005039	amidophosphoribosyltransferase; Provisional; Region: PRK07272
1088720005040	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
1088720005041	active site
1088720005042	tetramer interface [polypeptide binding]; other site
1088720005043	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1088720005044	active site
1088720005045	phosphoribosylformylglycinamidine synthase II; Provisional; Region: PRK01213
1088720005046	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
1088720005047	dimerization interface [polypeptide binding]; other site
1088720005048	ATP binding site [chemical binding]; other site
1088720005049	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
1088720005050	dimerization interface [polypeptide binding]; other site
1088720005051	ATP binding site [chemical binding]; other site
1088720005052	phosphoribosylformylglycinamidine synthase I; Provisional; Region: PRK03619
1088720005053	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
1088720005054	putative active site [active]
1088720005055	catalytic triad [active]
1088720005056	Phosphoribosylformylglycinamidine (FGAM) synthase; Region: PurS; pfam02700
1088720005057	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
1088720005058	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
1088720005059	ATP binding site [chemical binding]; other site
1088720005060	active site
1088720005061	substrate binding site [chemical binding]; other site
1088720005062	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
1088720005063	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
1088720005064	NAD binding site [chemical binding]; other site
1088720005065	ATP-grasp domain; Region: ATP-grasp; pfam02222
1088720005066	AIR carboxylase; Region: AIRC; pfam00731
1088720005067	Thiamine transporter protein (Thia_YuaJ); Region: Thia_YuaJ; pfam09515
1088720005068	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
1088720005069	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720005070	putative substrate translocation pore; other site
1088720005071	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720005072	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
1088720005073	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1088720005074	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1088720005075	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1088720005076	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1088720005077	dimerization domain swap beta strand [polypeptide binding]; other site
1088720005078	regulatory protein interface [polypeptide binding]; other site
1088720005079	active site
1088720005080	regulatory phosphorylation site [posttranslational modification]; other site
1088720005081	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1088720005082	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1088720005083	Walker A motif; other site
1088720005084	ATP binding site [chemical binding]; other site
1088720005085	Walker B motif; other site
1088720005086	arginine finger; other site
1088720005087	UvrB/uvrC motif; Region: UVR; pfam02151
1088720005088	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1088720005089	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1088720005090	Walker A motif; other site
1088720005091	ATP binding site [chemical binding]; other site
1088720005092	Walker B motif; other site
1088720005093	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1088720005094	Domain of unknown function (DUF1827); Region: DUF1827; pfam08860
1088720005095	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
1088720005096	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
1088720005097	G1 box; other site
1088720005098	putative GEF interaction site [polypeptide binding]; other site
1088720005099	GTP/Mg2+ binding site [chemical binding]; other site
1088720005100	Switch I region; other site
1088720005101	G2 box; other site
1088720005102	G3 box; other site
1088720005103	Switch II region; other site
1088720005104	G4 box; other site
1088720005105	G5 box; other site
1088720005106	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
1088720005107	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1088720005108	Domain of unknown function DUF21; Region: DUF21; pfam01595
1088720005109	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1088720005110	Transporter associated domain; Region: CorC_HlyC; pfam03471
1088720005111	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1088720005112	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1088720005113	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1088720005114	Coenzyme A binding pocket [chemical binding]; other site
1088720005115	hypothetical protein; Provisional; Region: PRK13662
1088720005116	RecX family; Region: RecX; cl00936
1088720005117	Mga helix-turn-helix domain; Region: Mga; pfam05043
1088720005118	TRAM domain; Region: TRAM; pfam01938
1088720005119	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
1088720005120	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1088720005121	S-adenosylmethionine binding site [chemical binding]; other site
1088720005122	Nucleoside 2-deoxyribosyltransferase; Region: Nuc_deoxyrib_tr; pfam05014
1088720005123	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
1088720005124	pyruvate oxidase; Region: pyruv_oxi_spxB; TIGR02720
1088720005125	PYR/PP interface [polypeptide binding]; other site
1088720005126	dimer interface [polypeptide binding]; other site
1088720005127	tetramer interface [polypeptide binding]; other site
1088720005128	TPP binding site [chemical binding]; other site
1088720005129	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1088720005130	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
1088720005131	TPP-binding site [chemical binding]; other site
1088720005132	"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are...; Region: init_cond_enzymes; cd00827
1088720005133	3-hydroxy-3-methylglutaryl CoA synthase, prokaryotic clade; Region: HMG-CoA-S_prok; TIGR01835
1088720005134	dimer interface [polypeptide binding]; other site
1088720005135	active site
1088720005136	Hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR); Region: HMG-CoA_reductase; cl00205
1088720005137	helix swapped region; other site
1088720005138	homodimer interface [polypeptide binding]; other site
1088720005139	substrate binding pocket [chemical binding]; other site
1088720005140	catalytic residues [active]
1088720005141	NADH/NADPH cofactor binding site [chemical binding]; other site
1088720005142	putative acyltransferase; Provisional; Region: PRK05790
1088720005143	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1088720005144	dimer interface [polypeptide binding]; other site
1088720005145	active site
1088720005146	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1088720005147	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
1088720005148	Metal-binding active site; metal-binding site
1088720005149	Restriction endonuclease; Region: Mrr_cat; pfam04471
1088720005150	aldose 1-epimerase superfamily; Region: Aldose_epim; cl14648
1088720005151	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK08588
1088720005152	Peptidase M20 acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase (ArgE/DapE)-like; Region: M20_ArgE_DapE_like; cd08659
1088720005153	metal binding site [ion binding]; metal-binding site
1088720005154	dimer interface [polypeptide binding]; other site
1088720005155	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
1088720005156	Predicted membrane protein [Function unknown]; Region: COG4684
1088720005157	potential protein location (hypothetical protein LRHK_1824 [Lactobacillus rhamnosus ATCC 8530]) that overlaps RNA (tRNA-L)
1088720005158	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1088720005159	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1088720005160	Coenzyme A binding pocket [chemical binding]; other site
1088720005161	SprT homologues; Region: SprT; cl01182
1088720005162	SprT-like family; Region: SprT-like; pfam10263
1088720005163	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: PhnK; COG1101
1088720005164	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720005165	Walker A/P-loop; other site
1088720005166	ATP binding site [chemical binding]; other site
1088720005167	Q-loop/lid; other site
1088720005168	ABC transporter signature motif; other site
1088720005169	Walker B; other site
1088720005170	D-loop; other site
1088720005171	H-loop/switch region; other site
1088720005172	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cd06574
1088720005173	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1088720005174	TM-ABC transporter signature motif; other site
1088720005175	Type I periplasmic ligand-binding domain of uncharacterized ABC-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_uncharacterized_transporter; cd06325
1088720005176	zinc binding site [ion binding]; other site
1088720005177	putative ligand binding site [chemical binding]; other site
1088720005178	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
1088720005179	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
1088720005180	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1088720005181	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1088720005182	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1088720005183	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1088720005184	Beta-lactamase; Region: Beta-lactamase; pfam00144
1088720005185	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1088720005186	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
1088720005187	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
1088720005188	homodimer interface [polypeptide binding]; other site
1088720005189	NAD binding pocket [chemical binding]; other site
1088720005190	ATP binding pocket [chemical binding]; other site
1088720005191	Mg binding site [ion binding]; other site
1088720005192	active-site loop [active]
1088720005193	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1088720005194	Beta-lactamase; Region: Beta-lactamase; pfam00144
1088720005195	nicotinate phosphoribosyltransferase; Validated; Region: PRK09243
1088720005196	Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction...; Region: NAPRTase_A; cd01570
1088720005197	active site
1088720005198	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1088720005199	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1088720005200	DNA-binding site [nucleotide binding]; DNA binding site
1088720005201	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
1088720005202	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
1088720005203	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
1088720005204	active site
1088720005205	dimer interface [polypeptide binding]; other site
1088720005206	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
1088720005207	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
1088720005208	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
1088720005209	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1088720005210	Domain of Unknown Function (DUF1542); Region: DUF1542; pfam07564
1088720005211	Mga helix-turn-helix domain; Region: Mga; pfam05043
1088720005212	putative phosphoesterase; Region: acc_ester; TIGR03729
1088720005213	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1088720005214	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720005215	putative substrate translocation pore; other site
1088720005216	POT family; Region: PTR2; pfam00854
1088720005217	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1088720005218	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1088720005219	Walker A/P-loop; other site
1088720005220	ATP binding site [chemical binding]; other site
1088720005221	Q-loop/lid; other site
1088720005222	ABC transporter signature motif; other site
1088720005223	Walker B; other site
1088720005224	D-loop; other site
1088720005225	H-loop/switch region; other site
1088720005226	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1088720005227	FtsX-like permease family; Region: FtsX; pfam02687
1088720005228	MFS/sugar transport protein; Region: MFS_2; pfam13347
1088720005229	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1088720005230	Alpha-L-fucosidase; Region: Alpha_L_fucos; cl12119
1088720005231	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
1088720005232	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1088720005233	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_HprK; cl00270
1088720005234	active site
1088720005235	nucleotide-binding site [chemical binding]; other site
1088720005236	Virus attachment protein p12 family; Region: P12; pfam12669
1088720005237	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
1088720005238	Nucleoside recognition; Region: Gate; pfam07670
1088720005239	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
1088720005240	Nucleoside recognition; Region: Gate; pfam07670
1088720005241	Ferrous iron transport protein B; Region: FeoB_N; pfam02421
1088720005242	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
1088720005243	G1 box; other site
1088720005244	GTP/Mg2+ binding site [chemical binding]; other site
1088720005245	Switch I region; other site
1088720005246	G2 box; other site
1088720005247	G3 box; other site
1088720005248	Switch II region; other site
1088720005249	G4 box; other site
1088720005250	G5 box; other site
1088720005251	FeoA domain; Region: FeoA; pfam04023
1088720005252	Fe2+ transport system protein A [Inorganic ion transport and metabolism]; Region: FeoA; COG1918
1088720005253	yrhL-like subfamily of SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_yrhL_like; cd01840
1088720005254	catalytic triad [active]
1088720005255	catalytic triad [active]
1088720005256	oxyanion hole [active]
1088720005257	AAA domain; Region: AAA_18; pfam13238
1088720005258	biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs; Region: BVR-B_like_SDR_a; cd05244
1088720005259	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1088720005260	NAD binding site [chemical binding]; other site
1088720005261	substrate binding site [chemical binding]; other site
1088720005262	putative active site [active]
1088720005263	seryl-tRNA synthetase; Provisional; Region: PRK05431
1088720005264	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1088720005265	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1088720005266	dimer interface [polypeptide binding]; other site
1088720005267	active site
1088720005268	motif 1; other site
1088720005269	motif 2; other site
1088720005270	motif 3; other site
1088720005271	Mga helix-turn-helix domain; Region: Mga; pfam05043
1088720005272	Mga helix-turn-helix domain; Region: Mga; pfam05043
1088720005273	lysine transporter; Provisional; Region: PRK10836
1088720005274	Alpha-acetolactate decarboxylase; Region: AAL_decarboxy; pfam03306
1088720005275	acetolactate synthase; Reviewed; Region: PRK08617
1088720005276	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1088720005277	PYR/PP interface [polypeptide binding]; other site
1088720005278	dimer interface [polypeptide binding]; other site
1088720005279	TPP binding site [chemical binding]; other site
1088720005280	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1088720005281	Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; composed of proteins similar to Klebsiella pneumoniae ALS, a catabolic enzyme required for butanediol fermentation. ALS catalyzes the conversion of 2...; Region: TPP_ALS; cd02010
1088720005282	TPP-binding site [chemical binding]; other site
1088720005283	dimer interface [polypeptide binding]; other site
1088720005284	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1088720005285	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1088720005286	Bacterial protein of unknown function (DUF916); Region: DUF916; pfam06030
1088720005287	Protein of unknown function C-terminal (DUF3324); Region: DUF3324; pfam11797
1088720005288	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
1088720005289	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1088720005290	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1088720005291	active site
1088720005292	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1088720005293	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1088720005294	ATP:dephospho-CoA triphosphoribosyl transferase; Region: CitG; cl00768
1088720005295	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1088720005296	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1088720005297	DNA-binding site [nucleotide binding]; DNA binding site
1088720005298	FCD domain; Region: FCD; pfam07729
1088720005299	oxaloacetate decarboxylase; Provisional; Region: PRK12331
1088720005300	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
1088720005301	active site
1088720005302	catalytic residues [active]
1088720005303	metal binding site [ion binding]; metal-binding site
1088720005304	homodimer binding site [polypeptide binding]; other site
1088720005305	2'-(5''-triphosphoribosyl)-3'- dephospho-CoA:apo-citrate lyase; Reviewed; Region: citX; PRK01392
1088720005306	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
1088720005307	Coenzyme A transferase; Region: CoA_trans; cl17247
1088720005308	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
1088720005309	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
1088720005310	citrate lyase subunit gamma; Provisional; Region: PRK13253
1088720005311	[citrate (pro-3S)-lyase] ligase; Region: cit_ly_ligase; TIGR00124
1088720005312	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1088720005313	active site
1088720005314	nucleotide binding site [chemical binding]; other site
1088720005315	HIGH motif; other site
1088720005316	KMSKS motif; other site
1088720005317	Oxaloacetate decarboxylase, gamma chain; Region: OAD_gamma; pfam04277
1088720005318	Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit [Energy production and conversion]; Region: OadB; COG1883
1088720005319	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06549
1088720005320	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1088720005321	carboxyltransferase (CT) interaction site; other site
1088720005322	biotinylation site [posttranslational modification]; other site
1088720005323	H+/citrate symporter [Energy production and conversion]; Region: CitM; COG2851
1088720005324	Citrate transporter; Region: CitMHS; pfam03600
1088720005325	RNA 2'-phosphotransferase; Reviewed; Region: PRK00819
1088720005326	RNA:NAD 2'-phosphotransferase [Translation, ribosomal structure and biogenesis]; Region: KptA; COG1859
1088720005327	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1088720005328	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1088720005329	Coenzyme A binding pocket [chemical binding]; other site
1088720005330	Predicted dinucleotide-binding enzymes [General function prediction only]; Region: COG2085
1088720005331	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; pfam03807
1088720005332	Predicted transcriptional regulators [Transcription]; Region: COG1695
1088720005333	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1088720005334	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
1088720005335	dimer interface [polypeptide binding]; other site
1088720005336	FMN binding site [chemical binding]; other site
1088720005337	NADPH bind site [chemical binding]; other site
1088720005338	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1088720005339	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1088720005340	Walker A/P-loop; other site
1088720005341	ATP binding site [chemical binding]; other site
1088720005342	Q-loop/lid; other site
1088720005343	ABC transporter signature motif; other site
1088720005344	Walker B; other site
1088720005345	D-loop; other site
1088720005346	H-loop/switch region; other site
1088720005347	Putative exporter of polyketide antibiotics [Cell envelope biogenesis, outer membrane]; Region: TnrB3; COG3559
1088720005348	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1088720005349	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1088720005350	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720005351	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1088720005352	putative substrate translocation pore; other site
1088720005353	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720005354	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1088720005355	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1088720005356	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1088720005357	non-specific DNA binding site [nucleotide binding]; other site
1088720005358	salt bridge; other site
1088720005359	sequence-specific DNA binding site [nucleotide binding]; other site
1088720005360	Alpha/beta hydrolase of unknown function (DUF915); Region: DUF915; pfam06028
1088720005361	Predicted transcriptional regulators [Transcription]; Region: COG1725
1088720005362	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1088720005363	DNA-binding site [nucleotide binding]; DNA binding site
1088720005364	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1088720005365	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720005366	Walker A/P-loop; other site
1088720005367	ATP binding site [chemical binding]; other site
1088720005368	Q-loop/lid; other site
1088720005369	ABC transporter signature motif; other site
1088720005370	Walker B; other site
1088720005371	D-loop; other site
1088720005372	H-loop/switch region; other site
1088720005373	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1088720005374	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1088720005375	Walker A/P-loop; other site
1088720005376	ATP binding site [chemical binding]; other site
1088720005377	Q-loop/lid; other site
1088720005378	ABC transporter signature motif; other site
1088720005379	Walker B; other site
1088720005380	D-loop; other site
1088720005381	H-loop/switch region; other site
1088720005382	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1088720005383	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1088720005384	Walker A/P-loop; other site
1088720005385	ATP binding site [chemical binding]; other site
1088720005386	Q-loop/lid; other site
1088720005387	ABC transporter signature motif; other site
1088720005388	Walker B; other site
1088720005389	D-loop; other site
1088720005390	H-loop/switch region; other site
1088720005391	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1088720005392	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1088720005393	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1088720005394	Walker A/P-loop; other site
1088720005395	ATP binding site [chemical binding]; other site
1088720005396	Q-loop/lid; other site
1088720005397	ABC transporter signature motif; other site
1088720005398	Walker B; other site
1088720005399	D-loop; other site
1088720005400	H-loop/switch region; other site
1088720005401	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1088720005402	nickel ABC transporter, permease subunit NikC; Region: nickel_nikC; TIGR02790
1088720005403	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1088720005404	dimer interface [polypeptide binding]; other site
1088720005405	conserved gate region; other site
1088720005406	putative PBP binding loops; other site
1088720005407	ABC-ATPase subunit interface; other site
1088720005408	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1088720005409	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1088720005410	dimer interface [polypeptide binding]; other site
1088720005411	conserved gate region; other site
1088720005412	putative PBP binding loops; other site
1088720005413	ABC-ATPase subunit interface; other site
1088720005414	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1088720005415	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1088720005416	peptide binding site [polypeptide binding]; other site
1088720005417	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1088720005418	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1088720005419	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720005420	Walker A/P-loop; other site
1088720005421	ATP binding site [chemical binding]; other site
1088720005422	Q-loop/lid; other site
1088720005423	ABC transporter signature motif; other site
1088720005424	Walker B; other site
1088720005425	D-loop; other site
1088720005426	H-loop/switch region; other site
1088720005427	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1088720005428	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1088720005429	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1088720005430	Walker A/P-loop; other site
1088720005431	ATP binding site [chemical binding]; other site
1088720005432	Q-loop/lid; other site
1088720005433	ABC transporter signature motif; other site
1088720005434	Walker B; other site
1088720005435	D-loop; other site
1088720005436	H-loop/switch region; other site
1088720005437	Phosphotransferase enzyme family; Region: APH; pfam01636
1088720005438	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1088720005439	substrate binding site [chemical binding]; other site
1088720005440	Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which...; Region: ZnMc; cl00064
1088720005441	active site
1088720005442	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1088720005443	non-specific DNA binding site [nucleotide binding]; other site
1088720005444	salt bridge; other site
1088720005445	sequence-specific DNA binding site [nucleotide binding]; other site
1088720005446	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1088720005447	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1088720005448	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1088720005449	non-specific DNA binding site [nucleotide binding]; other site
1088720005450	salt bridge; other site
1088720005451	sequence-specific DNA binding site [nucleotide binding]; other site
1088720005452	Mrr N-terminal domain; Region: Mrr_N; pfam14338
1088720005453	Restriction endonuclease; Region: Mrr_cat; pfam04471
1088720005454	Plasmid pRiA4b ORF-3-like protein; Region: PRiA4_ORF3; pfam07929
1088720005455	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1088720005456	Divergent AAA domain; Region: AAA_4; pfam04326
1088720005457	Abortive infection C-terminus; Region: Abi_C; pfam14355
1088720005458	GMP synthase; Reviewed; Region: guaA; PRK00074
1088720005459	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
1088720005460	AMP/PPi binding site [chemical binding]; other site
1088720005461	candidate oxyanion hole; other site
1088720005462	catalytic triad [active]
1088720005463	potential glutamine specificity residues [chemical binding]; other site
1088720005464	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
1088720005465	ATP Binding subdomain [chemical binding]; other site
1088720005466	Dimerization subdomain; other site
1088720005467	pantothenate kinase; Provisional; Region: PRK05439
1088720005468	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
1088720005469	ATP-binding site [chemical binding]; other site
1088720005470	CoA-binding site [chemical binding]; other site
1088720005471	Mg2+-binding site [ion binding]; other site
1088720005472	Peptidase family C69; Region: Peptidase_C69; pfam03577
1088720005473	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
1088720005474	Superfamily I DNA and RNA helicases [General function prediction only]; Region: COG3973
1088720005475	Part of AAA domain; Region: AAA_19; pfam13245
1088720005476	Family description; Region: UvrD_C_2; pfam13538
1088720005477	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
1088720005478	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
1088720005479	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
1088720005480	TrkA-C domain; Region: TrkA_C; pfam02080
1088720005481	proline-specific peptidase, Bacillus coagulans-type subfamily; Region: pro_imino_pep_2; TIGR01250
1088720005482	manganese transport protein MntH; Reviewed; Region: PRK00701
1088720005483	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
1088720005484	Ferrochelatase; Region: Ferrochelatase; pfam00762
1088720005485	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
1088720005486	C-terminal domain interface [polypeptide binding]; other site
1088720005487	active site
1088720005488	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
1088720005489	active site
1088720005490	N-terminal domain interface [polypeptide binding]; other site
1088720005491	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1088720005492	catalytic core [active]
1088720005493	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1088720005494	rhamnulose-1-phosphate aldolase; Provisional; Region: PRK03634
1088720005495	intersubunit interface [polypeptide binding]; other site
1088720005496	active site
1088720005497	Zn2+ binding site [ion binding]; other site
1088720005498	FtsX-like permease family; Region: FtsX; pfam02687
1088720005499	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1088720005500	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1088720005501	Walker A/P-loop; other site
1088720005502	ATP binding site [chemical binding]; other site
1088720005503	Q-loop/lid; other site
1088720005504	ABC transporter signature motif; other site
1088720005505	Walker B; other site
1088720005506	D-loop; other site
1088720005507	H-loop/switch region; other site
1088720005508	Amino acid permease; Region: AA_permease_2; pfam13520
1088720005509	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
1088720005510	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
1088720005511	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
1088720005512	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
1088720005513	HflX GTPase family; Region: HflX; cd01878
1088720005514	G1 box; other site
1088720005515	GTP/Mg2+ binding site [chemical binding]; other site
1088720005516	Switch I region; other site
1088720005517	G2 box; other site
1088720005518	G3 box; other site
1088720005519	Switch II region; other site
1088720005520	G4 box; other site
1088720005521	G5 box; other site
1088720005522	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1088720005523	Catalytic NodB homology domain of Streptococcus mutans polysaccharide deacetylase PgdA, Bacillus subtilis YheN, and similar proteins; Region: CE4_SmPgdA_like; cd10944
1088720005524	NodB motif; other site
1088720005525	active site
1088720005526	catalytic site [active]
1088720005527	Zn binding site [ion binding]; other site
1088720005528	NADH-ubiquinone/plastoquinone oxidoreductase chain 6; Region: Oxidored_q3; pfam00499
1088720005529	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
1088720005530	Sulfatase; Region: Sulfatase; cl17466
1088720005531	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
1088720005532	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1088720005533	Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane]; Region: COG3944
1088720005534	Chain length determinant protein; Region: Wzz; cl15801
1088720005535	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1088720005536	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1088720005537	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1088720005538	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1088720005539	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1088720005540	active site
1088720005541	Domain of unknown function (DUF3367); Region: DUF3367; pfam11847
1088720005542	AtlA is an autolysin found in Gram-positive lactic acid bacteria that degrades bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues. This family includes the AtlA and Aml...; Region: GH25_AtlA-like; cd06522
1088720005543	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
1088720005544	active site
1088720005545	SH3-like domain; Region: SH3_8; pfam13457
1088720005546	SH3-like domain; Region: SH3_8; pfam13457
1088720005547	SH3-like domain; Region: SH3_8; pfam13457
1088720005548	SH3-like domain; Region: SH3_8; pfam13457
1088720005549	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1088720005550	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
1088720005551	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1088720005552	Ligand binding site; other site
1088720005553	Putative Catalytic site; other site
1088720005554	DXD motif; other site
1088720005555	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
1088720005556	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1088720005557	active site
1088720005558	homodimer interface [polypeptide binding]; other site
1088720005559	exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025
1088720005560	Bacterial sugar transferase; Region: Bac_transf; pfam02397
1088720005561	Glycosyltransferase sugar-binding region containing DXD motif; Region: Gly_transf_sug; pfam04488
1088720005562	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1088720005563	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1088720005564	active site
1088720005565	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1088720005566	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
1088720005567	NAD(P) binding site [chemical binding]; other site
1088720005568	active site
1088720005569	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1088720005570	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1088720005571	dimer interface [polypeptide binding]; other site
1088720005572	conserved gate region; other site
1088720005573	putative PBP binding loops; other site
1088720005574	ABC-ATPase subunit interface; other site
1088720005575	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1088720005576	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1088720005577	dimer interface [polypeptide binding]; other site
1088720005578	conserved gate region; other site
1088720005579	putative PBP binding loops; other site
1088720005580	ABC-ATPase subunit interface; other site
1088720005581	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1088720005582	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1088720005583	substrate binding pocket [chemical binding]; other site
1088720005584	membrane-bound complex binding site; other site
1088720005585	hinge residues; other site
1088720005586	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1088720005587	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1088720005588	Walker A/P-loop; other site
1088720005589	ATP binding site [chemical binding]; other site
1088720005590	Q-loop/lid; other site
1088720005591	ABC transporter signature motif; other site
1088720005592	Walker B; other site
1088720005593	D-loop; other site
1088720005594	H-loop/switch region; other site
1088720005595	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1088720005596	metal binding site 2 [ion binding]; metal-binding site
1088720005597	putative DNA binding helix; other site
1088720005598	metal binding site 1 [ion binding]; metal-binding site
1088720005599	dimer interface [polypeptide binding]; other site
1088720005600	structural Zn2+ binding site [ion binding]; other site
1088720005601	Guanylate kinase; Region: Guanylate_kin; pfam00625
1088720005602	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1088720005603	catalytic site [active]
1088720005604	G-X2-G-X-G-K; other site
1088720005605	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1088720005606	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1088720005607	Coenzyme A binding pocket [chemical binding]; other site
1088720005608	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883
1088720005609	The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; Region: BAR; cl12013
1088720005610	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1088720005611	NlpC/P60 family; Region: NLPC_P60; pfam00877
1088720005612	tyrosyl-tRNA synthetase; Provisional; Region: PRK13354
1088720005613	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1088720005614	active site
1088720005615	HIGH motif; other site
1088720005616	dimer interface [polypeptide binding]; other site
1088720005617	KMSKS motif; other site
1088720005618	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1088720005619	RNA binding surface [nucleotide binding]; other site
1088720005620	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1088720005621	Cation efflux family; Region: Cation_efflux; cl00316
1088720005622	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1088720005623	dimerization interface [polypeptide binding]; other site
1088720005624	putative DNA binding site [nucleotide binding]; other site
1088720005625	putative Zn2+ binding site [ion binding]; other site
1088720005626	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
1088720005627	ApbE family; Region: ApbE; pfam02424
1088720005628	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
1088720005629	active site
1088720005630	homodimer interface [polypeptide binding]; other site
1088720005631	catalytic site [active]
1088720005632	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
1088720005633	homodimer interface [polypeptide binding]; other site
1088720005634	glycogen/starch/alpha-glucan phosphorylases; Region: P_ylase; TIGR02093
1088720005635	active site pocket [active]
1088720005636	glycogen synthase; Provisional; Region: glgA; PRK00654
1088720005637	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
1088720005638	ADP-binding pocket [chemical binding]; other site
1088720005639	homodimer interface [polypeptide binding]; other site
1088720005640	glucose-1-phosphate adenylyltransferase, GlgD subunit; Region: glgD; TIGR02092
1088720005641	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1088720005642	active site
1088720005643	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
1088720005644	dimer interface [polypeptide binding]; other site
1088720005645	N-terminal domain interface [polypeptide binding]; other site
1088720005646	sulfate 1 binding site; other site
1088720005647	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK05293
1088720005648	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
1088720005649	ligand binding site; other site
1088720005650	oligomer interface; other site
1088720005651	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
1088720005652	dimer interface [polypeptide binding]; other site
1088720005653	N-terminal domain interface [polypeptide binding]; other site
1088720005654	sulfate 1 binding site; other site
1088720005655	glycogen branching enzyme; Provisional; Region: PRK12313
1088720005656	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
1088720005657	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
1088720005658	active site
1088720005659	catalytic site [active]
1088720005660	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
1088720005661	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
1088720005662	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
1088720005663	homodimer interface [polypeptide binding]; other site
1088720005664	substrate-cofactor binding pocket; other site
1088720005665	catalytic residue [active]
1088720005666	Sortase family; Region: Sortase; pfam04203
1088720005667	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1088720005668	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1088720005669	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1088720005670	Firmicute fructose-1,6-bisphosphatase; Region: FBPase_2; pfam06874
1088720005671	Arsenate Reductase (ArsC) family, Spx subfamily; Spx is a unique RNA polymerase (RNAP)-binding protein present in bacilli and some mollicutes. It inhibits transcription by binding to the C-terminal domain of the alpha subunit of RNAP, disrupting complex...; Region: ArsC_Spx; cd03032
1088720005672	ArsC family; Region: ArsC; pfam03960
1088720005673	putative catalytic residues [active]
1088720005674	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1088720005675	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1088720005676	Walker A motif; other site
1088720005677	ATP binding site [chemical binding]; other site
1088720005678	Walker B motif; other site
1088720005679	arginine finger; other site
1088720005680	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1088720005681	Walker A motif; other site
1088720005682	ATP binding site [chemical binding]; other site
1088720005683	Walker B motif; other site
1088720005684	arginine finger; other site
1088720005685	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1088720005686	UDP-galactopyranose mutase [Cell envelope biogenesis, outer membrane]; Region: Glf; COG0562
1088720005687	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1088720005688	UDP-galactopyranose mutase; Region: GLF; pfam03275
1088720005689	Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: CapC; COG4464
1088720005690	Cell envelope-related transcriptional attenuator domain; Region: LytR_cpsA_psr; cl00581
1088720005691	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
1088720005692	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1088720005693	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1088720005694	Bacterial sugar transferase; Region: Bac_transf; pfam02397
1088720005695	Domain of unknown function (DUF4422); Region: DUF4422; pfam14393
1088720005696	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1088720005697	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1088720005698	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; pfam04230
1088720005699	putative glycosyl transferase; Provisional; Region: PRK10073
1088720005700	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1088720005701	active site
1088720005702	UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase; Provisional; Region: PRK09922
1088720005703	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
1088720005704	putative ADP-binding pocket [chemical binding]; other site
1088720005705	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1088720005706	active site
1088720005707	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1088720005708	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1088720005709	active site
1088720005710	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
1088720005711	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1088720005712	Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane]; Region: COG3944
1088720005713	Chain length determinant protein; Region: Wzz; cl15801
1088720005714	yrhL-like subfamily of SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_yrhL_like; cd01840
1088720005715	catalytic triad [active]
1088720005716	catalytic triad [active]
1088720005717	oxyanion hole [active]
1088720005718	QueT transporter; Region: QueT; pfam06177
1088720005719	classical (c) SDRs; Region: SDR_c; cd05233
1088720005720	NAD(P) binding site [chemical binding]; other site
1088720005721	active site
1088720005722	Protein of unknown function (DUF2829); Region: DUF2829; pfam11195
1088720005723	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1088720005724	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1088720005725	non-specific DNA binding site [nucleotide binding]; other site
1088720005726	salt bridge; other site
1088720005727	sequence-specific DNA binding site [nucleotide binding]; other site
1088720005728	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1088720005729	catalytic core [active]
1088720005730	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1088720005731	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1088720005732	Walker A/P-loop; other site
1088720005733	ATP binding site [chemical binding]; other site
1088720005734	Q-loop/lid; other site
1088720005735	ABC transporter signature motif; other site
1088720005736	Walker B; other site
1088720005737	D-loop; other site
1088720005738	H-loop/switch region; other site
1088720005739	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1088720005740	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1088720005741	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1088720005742	Walker A/P-loop; other site
1088720005743	ATP binding site [chemical binding]; other site
1088720005744	Q-loop/lid; other site
1088720005745	ABC transporter signature motif; other site
1088720005746	Walker B; other site
1088720005747	D-loop; other site
1088720005748	H-loop/switch region; other site
1088720005749	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1088720005750	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1088720005751	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1088720005752	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1088720005753	dimer interface [polypeptide binding]; other site
1088720005754	conserved gate region; other site
1088720005755	putative PBP binding loops; other site
1088720005756	ABC-ATPase subunit interface; other site
1088720005757	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1088720005758	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1088720005759	dimer interface [polypeptide binding]; other site
1088720005760	conserved gate region; other site
1088720005761	putative PBP binding loops; other site
1088720005762	ABC-ATPase subunit interface; other site
1088720005763	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1088720005764	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1088720005765	peptide binding site [polypeptide binding]; other site
1088720005766	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720005767	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1088720005768	putative substrate translocation pore; other site
1088720005769	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720005770	elongation factor P; Validated; Region: PRK00529
1088720005771	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1088720005772	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1088720005773	RNA binding site [nucleotide binding]; other site
1088720005774	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1088720005775	RNA binding site [nucleotide binding]; other site
1088720005776	Uncharacterized conserved protein [Function unknown]; Region: COG1556
1088720005777	Uncharacterized conserved protein containing a ferredoxin-like domain [Energy production and conversion]; Region: COG1139
1088720005778	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
1088720005779	4Fe-4S binding domain; Region: Fer4; pfam00037
1088720005780	CoB--CoM heterodisulfide reductase, subunit B; Region: CoB_CoM_SS_B; TIGR03288
1088720005781	Cysteine-rich domain; Region: CCG; pfam02754
1088720005782	Cysteine-rich domain; Region: CCG; pfam02754
1088720005783	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1088720005784	active site
1088720005785	methionine cluster; other site
1088720005786	phosphorylation site [posttranslational modification]
1088720005787	metal binding site [ion binding]; metal-binding site
1088720005788	Uncharacterized conserved protein [Function unknown]; Region: COG3589
1088720005789	Bacterial protein of unknown function (DUF871); Region: DUF871; pfam05913
1088720005790	Domain of unknown function (DUF3284); Region: DUF3284; pfam11687
1088720005791	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1088720005792	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1088720005793	Alpha-galactosidase [Carbohydrate transport and metabolism]; Region: GalA; COG3345
1088720005794	Melibiase; Region: Melibiase; pfam02065
1088720005795	hypothetical protein; Validated; Region: PRK02101
1088720005796	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1088720005797	DNA binding residues [nucleotide binding]
1088720005798	Winged helix-turn helix; Region: HTH_29; pfam13551
1088720005799	Uncharacterized protein conserved in bacteria (DUF2087); Region: DUF2087; pfam09860
1088720005800	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
1088720005801	AAA domain; Region: AAA_30; pfam13604
1088720005802	Family description; Region: UvrD_C_2; pfam13538
1088720005803	WxL domain surface cell wall-binding; Region: WxL; pfam13731
1088720005804	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1088720005805	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
1088720005806	substrate binding site [chemical binding]; other site
1088720005807	ATP binding site [chemical binding]; other site
1088720005808	N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuA; COG0145
1088720005809	Hydantoinase/oxoprolinase N-terminal region; Region: Hydant_A_N; pfam05378
1088720005810	Hydantoinase/oxoprolinase; Region: Hydantoinase_A; pfam01968
1088720005811	Uncharacterized conserved protein [Function unknown]; Region: COG3535
1088720005812	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
1088720005813	Na binding site [ion binding]; other site
1088720005814	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1088720005815	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1088720005816	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1088720005817	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
1088720005818	Int/Topo IB signature motif; other site
1088720005819	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1088720005820	HsdM N-terminal domain; Region: HsdM_N; pfam12161
1088720005821	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
1088720005822	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1088720005823	type I site-specific deoxyribonuclease, HsdR family; Region: hsdR; TIGR00348
1088720005824	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
1088720005825	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1088720005826	ATP binding site [chemical binding]; other site
1088720005827	putative Mg++ binding site [ion binding]; other site
1088720005828	Type I restriction and modification enzyme - subunit R C terminal; Region: EcoR124_C; pfam12008
1088720005829	looped-hinge helix DNA binding domain, AbrB family; Region: lp_hng_hel_AbrB; TIGR01439
1088720005830	Protein of unknown function (DUF998); Region: DUF998; pfam06197
1088720005831	Predicted membrane protein [Function unknown]; Region: COG1511
1088720005832	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
1088720005833	YhgE/Pip C-terminal domain; Region: pip_yhgE_Cterm; TIGR03062
1088720005834	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
1088720005835	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1088720005836	active site turn [active]
1088720005837	phosphorylation site [posttranslational modification]
1088720005838	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1088720005839	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
1088720005840	HPr interaction site; other site
1088720005841	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1088720005842	active site
1088720005843	phosphorylation site [posttranslational modification]
1088720005844	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
1088720005845	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1088720005846	Ca binding site [ion binding]; other site
1088720005847	active site
1088720005848	catalytic site [active]
1088720005849	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1088720005850	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1088720005851	DNA binding site [nucleotide binding]
1088720005852	domain linker motif; other site
1088720005853	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1088720005854	sucrose-6-phosphate hydrolase; Region: scrB_fam; TIGR01322
1088720005855	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
1088720005856	substrate binding [chemical binding]; other site
1088720005857	active site
1088720005858	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
1088720005859	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
1088720005860	NmrA-like family; Region: NmrA; pfam05368
1088720005861	NADP binding site [chemical binding]; other site
1088720005862	Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane]; Region: Cfa; COG2230
1088720005863	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1088720005864	S-adenosylmethionine binding site [chemical binding]; other site
1088720005865	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
1088720005866	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
1088720005867	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
1088720005868	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
1088720005869	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1088720005870	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1088720005871	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1088720005872	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1088720005873	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1088720005874	carboxyltransferase (CT) interaction site; other site
1088720005875	biotinylation site [posttranslational modification]; other site
1088720005876	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
1088720005877	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1088720005878	dimer interface [polypeptide binding]; other site
1088720005879	active site
1088720005880	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1088720005881	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
1088720005882	NAD(P) binding site [chemical binding]; other site
1088720005883	homotetramer interface [polypeptide binding]; other site
1088720005884	homodimer interface [polypeptide binding]; other site
1088720005885	active site
1088720005886	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1088720005887	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1088720005888	putative enoyl-[acyl-carrier-protein] reductase II; Region: enACPred_II; TIGR03151
1088720005889	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
1088720005890	FMN binding site [chemical binding]; other site
1088720005891	substrate binding site [chemical binding]; other site
1088720005892	putative catalytic residue [active]
1088720005893	acyl carrier protein; Provisional; Region: acpP; PRK00982
1088720005894	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1088720005895	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
1088720005896	dimer interface [polypeptide binding]; other site
1088720005897	active site
1088720005898	CoA binding pocket [chemical binding]; other site
1088720005899	MarR family; Region: MarR; pfam01047
1088720005900	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1088720005901	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1088720005902	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
1088720005903	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
1088720005904	dimer interface [polypeptide binding]; other site
1088720005905	active site
1088720005906	metal binding site [ion binding]; metal-binding site
1088720005907	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
1088720005908	active site residue [active]
1088720005909	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1088720005910	MarR family; Region: MarR_2; pfam12802
1088720005911	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1088720005912	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1088720005913	I-site; other site
1088720005914	Bacterial cellulose synthase subunit; Region: BcsB; cl15851
1088720005915	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
1088720005916	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1088720005917	DXD motif; other site
1088720005918	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1088720005919	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1088720005920	metal binding site [ion binding]; metal-binding site
1088720005921	active site
1088720005922	I-site; other site
1088720005923	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
1088720005924	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1088720005925	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1088720005926	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1088720005927	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1088720005928	MarR family; Region: MarR_2; pfam12802
1088720005929	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
1088720005930	Double zinc ribbon; Region: DZR; pfam12773
1088720005931	Putative esterase; Region: Esterase; pfam00756
1088720005932	S-formylglutathione hydrolase; Region: PLN02442
1088720005933	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
1088720005934	Double zinc ribbon; Region: DZR; pfam12773
1088720005935	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1088720005936	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1088720005937	putative Zn2+ binding site [ion binding]; other site
1088720005938	putative DNA binding site [nucleotide binding]; other site
1088720005939	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_18; cd04677
1088720005940	nudix motif; other site
1088720005941	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1088720005942	catalytic core [active]
1088720005943	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1088720005944	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1088720005945	Beta-lactamase; Region: Beta-lactamase; pfam00144
1088720005946	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1088720005947	Sortase A (SrtA) or subfamily-1 sortases are cysteine transpeptidases found in gram-positive bacteria that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. They do so by catalyzing a transpeptidation reaction in which the...; Region: Sortase_A_1; cd06165
1088720005948	active site
1088720005949	catalytic site [active]
1088720005950	Predicted membrane protein [Function unknown]; Region: COG2246
1088720005951	GtrA-like protein; Region: GtrA; pfam04138
1088720005952	pyruvate oxidase; Region: pyruv_oxi_spxB; TIGR02720
1088720005953	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
1088720005954	PYR/PP interface [polypeptide binding]; other site
1088720005955	tetramer interface [polypeptide binding]; other site
1088720005956	dimer interface [polypeptide binding]; other site
1088720005957	TPP binding site [chemical binding]; other site
1088720005958	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1088720005959	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
1088720005960	TPP-binding site [chemical binding]; other site
1088720005961	ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; cl17891
1088720005962	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1088720005963	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1088720005964	glycine betaine transporter membrane protein; Provisional; Region: PRK10952
1088720005965	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1088720005966	dimer interface [polypeptide binding]; other site
1088720005967	conserved gate region; other site
1088720005968	putative PBP binding loops; other site
1088720005969	ABC-ATPase subunit interface; other site
1088720005970	ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism]; Region: ProV; COG4175
1088720005971	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
1088720005972	Walker A/P-loop; other site
1088720005973	ATP binding site [chemical binding]; other site
1088720005974	Q-loop/lid; other site
1088720005975	ABC transporter signature motif; other site
1088720005976	Walker B; other site
1088720005977	D-loop; other site
1088720005978	H-loop/switch region; other site
1088720005979	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
1088720005980	Sugar fermentation stimulation protein; Region: SfsA; cl00647
1088720005981	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1088720005982	Ligand Binding Site [chemical binding]; other site
1088720005983	Predicted ATP-grasp enzyme [General function prediction only]; Region: COG3919
1088720005984	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
1088720005985	homoserine kinase; Provisional; Region: PRK01212
1088720005986	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1088720005987	threonine synthase; Validated; Region: PRK09225
1088720005988	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
1088720005989	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1088720005990	catalytic residue [active]
1088720005991	Homoserine dehydrogenase [Amino acid transport and metabolism]; Region: ThrA; COG0460
1088720005992	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1088720005993	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1088720005994	aspartate kinase; Reviewed; Region: PRK09034
1088720005995	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
1088720005996	nucleotide binding site [chemical binding]; other site
1088720005997	substrate binding site [chemical binding]; other site
1088720005998	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1088720005999	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1088720006000	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
1088720006001	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
1088720006002	Predicted membrane protein, putative toxin regulator [General function prediction only]; Region: PfoR; COG3641
1088720006003	Phosphotransferase system, EIIC; Region: PTS_EIIC_2; pfam13303
1088720006004	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
1088720006005	D-Lactate dehydrogenase and D-2-Hydroxyisocaproic acid dehydrogenase (D-HicDH), NAD-binding and catalytic domains; Region: LDH; cd12186
1088720006006	homodimer interface [polypeptide binding]; other site
1088720006007	ligand binding site [chemical binding]; other site
1088720006008	NAD binding site [chemical binding]; other site
1088720006009	catalytic site [active]
1088720006010	aromatic amino acid aminotransferase; Validated; Region: PRK07309
1088720006011	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1088720006012	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1088720006013	homodimer interface [polypeptide binding]; other site
1088720006014	catalytic residue [active]
1088720006015	Mitochondrial biogenesis AIM24; Region: AIM24; pfam01987
1088720006016	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1088720006017	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1088720006018	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1088720006019	Transcriptional regulator C-terminal region; Region: TetR_C_8; pfam14278
1088720006020	Predicted membrane protein [Function unknown]; Region: COG1511
1088720006021	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
1088720006022	YhgE/Pip C-terminal domain; Region: pip_yhgE_Cterm; TIGR03062
1088720006023	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1088720006024	Cation efflux family; Region: Cation_efflux; pfam01545
1088720006025	Asparagine synthase (glutamine-hydrolyzing) [Amino acid transport and metabolism]; Region: AsnB; COG0367
1088720006026	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
1088720006027	active site
1088720006028	dimer interface [polypeptide binding]; other site
1088720006029	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
1088720006030	Ligand Binding Site [chemical binding]; other site
1088720006031	Molecular Tunnel; other site
1088720006032	Predicted phosphohydrolases [General function prediction only]; Region: Icc; COG1409
1088720006033	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
1088720006034	active site
1088720006035	metal binding site [ion binding]; metal-binding site
1088720006036	1,4-dihydroxy-2-naphthoate octaprenyltransferase [Coenzyme metabolism]; Region: MenA; cl17224
1088720006037	UbiA prenyltransferase family; Region: UbiA; pfam01040
1088720006038	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1088720006039	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1088720006040	substrate binding pocket [chemical binding]; other site
1088720006041	chain length determination region; other site
1088720006042	substrate-Mg2+ binding site; other site
1088720006043	catalytic residues [active]
1088720006044	aspartate-rich region 1; other site
1088720006045	active site lid residues [active]
1088720006046	aspartate-rich region 2; other site
1088720006047	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
1088720006048	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4152
1088720006049	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720006050	Walker A/P-loop; other site
1088720006051	ATP binding site [chemical binding]; other site
1088720006052	Q-loop/lid; other site
1088720006053	ABC transporter signature motif; other site
1088720006054	Walker B; other site
1088720006055	D-loop; other site
1088720006056	H-loop/switch region; other site
1088720006057	Domain of unknown function (DUF4162); Region: DUF4162; pfam13732
1088720006058	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
1088720006059	Predicted transcriptional regulators [Transcription]; Region: COG1725
1088720006060	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1088720006061	DNA-binding site [nucleotide binding]; DNA binding site
1088720006062	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1088720006063	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1088720006064	Walker A/P-loop; other site
1088720006065	ATP binding site [chemical binding]; other site
1088720006066	Q-loop/lid; other site
1088720006067	ABC transporter signature motif; other site
1088720006068	Walker B; other site
1088720006069	D-loop; other site
1088720006070	H-loop/switch region; other site
1088720006071	glucose-1-dehydrogenase; Provisional; Region: PRK08936
1088720006072	glucose 1 dehydrogenase (GlcDH), classical (c) SDRs; Region: GlcDH_SDR_c; cd05358
1088720006073	NAD binding site [chemical binding]; other site
1088720006074	homodimer interface [polypeptide binding]; other site
1088720006075	active site
1088720006076	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
1088720006077	beta-galactosidase; Region: BGL; TIGR03356
1088720006078	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1088720006079	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
1088720006080	active site turn [active]
1088720006081	phosphorylation site [posttranslational modification]
1088720006082	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1088720006083	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1088720006084	HPr interaction site; other site
1088720006085	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1088720006086	active site
1088720006087	phosphorylation site [posttranslational modification]
1088720006088	transcriptional antiterminator BglG; Provisional; Region: PRK09772
1088720006089	CAT RNA binding domain; Region: CAT_RBD; smart01061
1088720006090	PRD domain; Region: PRD; pfam00874
1088720006091	PRD domain; Region: PRD; pfam00874
1088720006092	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1088720006093	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1088720006094	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1088720006095	Walker A/P-loop; other site
1088720006096	ATP binding site [chemical binding]; other site
1088720006097	Q-loop/lid; other site
1088720006098	ABC transporter signature motif; other site
1088720006099	Walker B; other site
1088720006100	D-loop; other site
1088720006101	H-loop/switch region; other site
1088720006102	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydD; COG4988
1088720006103	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1088720006104	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720006105	Walker A/P-loop; other site
1088720006106	ATP binding site [chemical binding]; other site
1088720006107	Q-loop/lid; other site
1088720006108	ABC transporter signature motif; other site
1088720006109	Walker B; other site
1088720006110	D-loop; other site
1088720006111	H-loop/switch region; other site
1088720006112	Listerrria innocua Lin0431  is similar to the N-Utilization Substance G (NusG) N terminal (NGN) insert (DII); Region: Lin0431_like; cd09911
1088720006113	trimer interface [polypeptide binding]; other site
1088720006114	ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydC; COG4987
1088720006115	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1088720006116	ATP-binding cassette domain of CydCD, subfamily C; Region: ABCC_cytochrome_bd; cd03247
1088720006117	Walker A/P-loop; other site
1088720006118	ATP binding site [chemical binding]; other site
1088720006119	Q-loop/lid; other site
1088720006120	ABC transporter signature motif; other site
1088720006121	Walker B; other site
1088720006122	D-loop; other site
1088720006123	H-loop/switch region; other site
1088720006124	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydD; COG4988
1088720006125	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1088720006126	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720006127	Walker A/P-loop; other site
1088720006128	ATP binding site [chemical binding]; other site
1088720006129	Q-loop/lid; other site
1088720006130	ABC transporter signature motif; other site
1088720006131	Walker B; other site
1088720006132	D-loop; other site
1088720006133	H-loop/switch region; other site
1088720006134	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1088720006135	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
1088720006136	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
1088720006137	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
1088720006138	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1088720006139	pyrimidine-nucleoside phosphorylase; Region: Y_phosphoryl; TIGR02644
1088720006140	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1088720006141	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; smart00941
1088720006142	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1088720006143	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
1088720006144	active site
1088720006145	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1088720006146	EamA-like transporter family; Region: EamA; pfam00892
1088720006147	EamA-like transporter family; Region: EamA; pfam00892
1088720006148	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
1088720006149	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1088720006150	Ligand Binding Site [chemical binding]; other site
1088720006151	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1088720006152	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1088720006153	non-specific DNA binding site [nucleotide binding]; other site
1088720006154	salt bridge; other site
1088720006155	sequence-specific DNA binding site [nucleotide binding]; other site
1088720006156	Tyrosine phosphatase family; Region: Y_phosphatase3; pfam13350
1088720006157	Tyrosine phosphatase family C-terminal region; Region: Y_phosphatase3C; pfam13348
1088720006158	epoxyqueuosine reductase; Region: TIGR00276
1088720006159	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
1088720006160	Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; Region: ARM; cl02500
1088720006161	protein binding surface [polypeptide binding]; other site
1088720006162	BioY family; Region: BioY; pfam02632
1088720006163	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1088720006164	S-adenosylmethionine binding site [chemical binding]; other site
1088720006165	GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518
1088720006166	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
1088720006167	catalytic triad [active]
1088720006168	Uncharacterized protein conserved in bacteria (DUF2263); Region: DUF2263; pfam10021
1088720006169	Macro domain, a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Some macro domains recognize poly...; Region: Macro; cl00019
1088720006170	Alpha/beta hydrolase of unknown function (DUF915); Region: DUF915; pfam06028
1088720006171	Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism]; Region: NolL; COG3594
1088720006172	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1088720006173	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720006174	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1088720006175	Maf-like protein; Region: Maf; pfam02545
1088720006176	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1088720006177	active site
1088720006178	dimer interface [polypeptide binding]; other site
1088720006179	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
1088720006180	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1088720006181	ATP binding site [chemical binding]; other site
1088720006182	Mg2+ binding site [ion binding]; other site
1088720006183	G-X-G motif; other site
1088720006184	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
1088720006185	ATP binding site [chemical binding]; other site
1088720006186	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
1088720006187	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
1088720006188	MutS domain I; Region: MutS_I; pfam01624
1088720006189	MutS domain II; Region: MutS_II; pfam05188
1088720006190	MutS domain III; Region: MutS_III; pfam05192
1088720006191	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
1088720006192	Walker A/P-loop; other site
1088720006193	ATP binding site [chemical binding]; other site
1088720006194	Q-loop/lid; other site
1088720006195	ABC transporter signature motif; other site
1088720006196	Walker B; other site
1088720006197	D-loop; other site
1088720006198	H-loop/switch region; other site
1088720006199	Amino acid permease; Region: AA_permease_2; pfam13520
1088720006200	Domain of unknown function (DUF1827); Region: DUF1827; pfam08860
1088720006201	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
1088720006202	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1088720006203	ring oligomerisation interface [polypeptide binding]; other site
1088720006204	ATP/Mg binding site [chemical binding]; other site
1088720006205	stacking interactions; other site
1088720006206	hinge regions; other site
1088720006207	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1088720006208	oligomerisation interface [polypeptide binding]; other site
1088720006209	mobile loop; other site
1088720006210	roof hairpin; other site
1088720006211	CAAX protease self-immunity; Region: Abi; pfam02517
1088720006212	Cell envelope-related transcriptional attenuator domain; Region: LytR_cpsA_psr; cl00581
1088720006213	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1088720006214	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1088720006215	Walker A/P-loop; other site
1088720006216	ATP binding site [chemical binding]; other site
1088720006217	Q-loop/lid; other site
1088720006218	ABC transporter signature motif; other site
1088720006219	Walker B; other site
1088720006220	D-loop; other site
1088720006221	H-loop/switch region; other site
1088720006222	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1088720006223	DNA-binding site [nucleotide binding]; DNA binding site
1088720006224	redox-sensing transcriptional repressor Rex; Provisional; Region: PRK05472
1088720006225	Putative DNA-binding protein N-terminus; Region: Put_DNA-bind_N; pfam06971
1088720006226	CoA binding domain; Region: CoA_binding; pfam02629
1088720006227	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1088720006228	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720006229	Walker A/P-loop; other site
1088720006230	ATP binding site [chemical binding]; other site
1088720006231	Q-loop/lid; other site
1088720006232	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1088720006233	ABC transporter signature motif; other site
1088720006234	Walker B; other site
1088720006235	D-loop; other site
1088720006236	ABC transporter; Region: ABC_tran_2; pfam12848
1088720006237	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1088720006238	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1088720006239	active site
1088720006240	P-loop; other site
1088720006241	phosphorylation site [posttranslational modification]
1088720006242	UGMP family protein; Validated; Region: PRK09604
1088720006243	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
1088720006244	Carbamoyltransferase; Region: CmcH_NodU; pfam02543
1088720006245	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
1088720006246	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1088720006247	Coenzyme A binding pocket [chemical binding]; other site
1088720006248	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
1088720006249	Glycoprotease family; Region: Peptidase_M22; pfam00814
1088720006250	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
1088720006251	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
1088720006252	active site
1088720006253	homodimer interface [polypeptide binding]; other site
1088720006254	homotetramer interface [polypeptide binding]; other site
1088720006255	Acyl-ACP thioesterase; Region: Acyl-ACP_TE; pfam01643
1088720006256	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1088720006257	active site
1088720006258	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
1088720006259	active site 2 [active]
1088720006260	active site 1 [active]
1088720006261	Predicted methyltransferases [General function prediction only]; Region: COG0313
1088720006262	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1088720006263	putative SAM binding site [chemical binding]; other site
1088720006264	putative homodimer interface [polypeptide binding]; other site
1088720006265	Protein of unknown function (DUF972); Region: DUF972; pfam06156
1088720006266	DNA polymerase III subunit delta'; Validated; Region: PRK08058
1088720006267	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1088720006268	Protein of unknown function (DUF970); Region: DUF970; pfam06153
1088720006269	thymidylate kinase; Validated; Region: tmk; PRK00698
1088720006270	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1088720006271	TMP-binding site; other site
1088720006272	ATP-binding site [chemical binding]; other site
1088720006273	Protein of unknown function (DUF2508); Region: DUF2508; pfam10704
1088720006274	recombination protein RecR; Reviewed; Region: recR; PRK00076
1088720006275	RecR protein; Region: RecR; pfam02132
1088720006276	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
1088720006277	putative active site [active]
1088720006278	putative metal-binding site [ion binding]; other site
1088720006279	tetramer interface [polypeptide binding]; other site
1088720006280	hypothetical protein; Validated; Region: PRK00153
1088720006281	DNA polymerase III subunits gamma and tau; Validated; Region: PRK05563
1088720006282	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1088720006283	Walker A motif; other site
1088720006284	ATP binding site [chemical binding]; other site
1088720006285	Walker B motif; other site
1088720006286	arginine finger; other site
1088720006287	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
1088720006288	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1088720006289	nucleoside/Zn binding site; other site
1088720006290	dimer interface [polypeptide binding]; other site
1088720006291	catalytic motif [active]
1088720006292	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1088720006293	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1088720006294	S-adenosylmethionine binding site [chemical binding]; other site
1088720006295	Predicted integral membrane protein [Function unknown]; Region: COG0392
1088720006296	Uncharacterized conserved protein [Function unknown]; Region: COG2898
1088720006297	Uncharacterized conserved protein (DUF2156); Region: DUF2156; pfam09924
1088720006298	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cl02788
1088720006299	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
1088720006300	Probable transposase; Region: OrfB_IS605; pfam01385
1088720006301	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
1088720006302	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
1088720006303	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1088720006304	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1088720006305	DNA binding site [nucleotide binding]
1088720006306	domain linker motif; other site
1088720006307	Ligand-binding domain of a novel transcription factor implicated in catabolite repression in Bacillus and Clostridium species; Region: PBP1_CcpB_like; cd06286
1088720006308	putative dimerization interface [polypeptide binding]; other site
1088720006309	putative ligand binding site [chemical binding]; other site
1088720006310	Peptidase S8 family domain in Streptococcal C5a peptidases; Region: Peptidases_S8_C5a_Peptidase; cd07475
1088720006311	putative active site [active]
1088720006312	catalytic triad [active]
1088720006313	Peptidase S8 family domain in Streptococcal C5a peptidases; Region: Peptidases_S8_C5a_Peptidase; cd07475
1088720006314	putative active site [active]
1088720006315	Fn3-like domain (DUF1034); Region: DUF1034; pfam06280
1088720006316	peptidylprolyl isomerase; Provisional; Region: prsA; PRK04405
1088720006317	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1088720006318	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1088720006319	core dimer interface [polypeptide binding]; other site
1088720006320	peripheral dimer interface [polypeptide binding]; other site
1088720006321	L10 interface [polypeptide binding]; other site
1088720006322	L11 interface [polypeptide binding]; other site
1088720006323	putative EF-Tu interaction site [polypeptide binding]; other site
1088720006324	putative EF-G interaction site [polypeptide binding]; other site
1088720006325	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1088720006326	23S rRNA interface [nucleotide binding]; other site
1088720006327	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1088720006328	drug efflux system protein MdtG; Provisional; Region: PRK09874
1088720006329	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720006330	putative substrate translocation pore; other site
1088720006331	benzoate transport; Region: 2A0115; TIGR00895
1088720006332	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720006333	putative substrate translocation pore; other site
1088720006334	Domain of unknown function (DUF1975); Region: DUF1975; pfam09318
1088720006335	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1088720006336	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1088720006337	Domain of unknown function (DUF1975); Region: DUF1975; pfam09318
1088720006338	This family is most closely related to the GT1 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding.  In...; Region: GT1_gtfA_like; cd04949
1088720006339	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1088720006340	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1088720006341	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
1088720006342	NAD(P) binding site [chemical binding]; other site
1088720006343	catalytic residues [active]
1088720006344	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1088720006345	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1088720006346	Coenzyme A binding pocket [chemical binding]; other site
1088720006347	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1088720006348	mRNA/rRNA interface [nucleotide binding]; other site
1088720006349	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1088720006350	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1088720006351	23S rRNA interface [nucleotide binding]; other site
1088720006352	L7/L12 interface [polypeptide binding]; other site
1088720006353	putative thiostrepton binding site; other site
1088720006354	L25 interface [polypeptide binding]; other site
1088720006355	magnesium-transporting ATPase; Provisional; Region: PRK15122
1088720006356	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
1088720006357	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1088720006358	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1088720006359	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1088720006360	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1088720006361	amidase; Provisional; Region: PRK06529
1088720006362	Amidase; Region: Amidase; cl11426
1088720006363	Cobalamin adenosyltransferase; Region: Cob_adeno_trans; pfam01923
1088720006364	ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent; Region: RTPR; TIGR02505
1088720006365	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
1088720006366	Nucleoside 2-deoxyribosyltransferase; Region: Nuc_deoxyrib_tr; pfam05014
1088720006367	Alpha/beta hydrolase of unknown function (DUF915); Region: DUF915; pfam06028
1088720006368	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1088720006369	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1088720006370	putative homodimer interface [polypeptide binding]; other site
1088720006371	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1088720006372	heterodimer interface [polypeptide binding]; other site
1088720006373	homodimer interface [polypeptide binding]; other site
1088720006374	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK07597
1088720006375	1,4-dihydroxy-2-naphthoate octaprenyltransferase [Coenzyme metabolism]; Region: MenA; cl17224
1088720006376	1,4-dihydroxy-2-naphthoate octaprenyltransferase [Coenzyme metabolism]; Region: MenA; cl17224
1088720006377	UbiA prenyltransferase family; Region: UbiA; pfam01040
1088720006378	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
1088720006379	ApbE family; Region: ApbE; pfam02424
1088720006380	Probable transposase; Region: OrfB_IS605; pfam01385
1088720006381	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
1088720006382	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
1088720006383	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
1088720006384	This conserved region includes the FMN-binding site of the NqrC protein as well as the NosR and NirI regulatory proteins; Region: FMN_bind; smart00900
1088720006385	This conserved region includes the FMN-binding site of the NqrC protein as well as the NosR and NirI regulatory proteins; Region: FMN_bind; smart00900
1088720006386	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
1088720006387	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1088720006388	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1088720006389	Listerrria innocua Lin0431  is similar to the N-Utilization Substance G (NusG) N terminal (NGN) insert (DII); Region: Lin0431_like; cd09911
1088720006390	trimer interface [polypeptide binding]; other site
1088720006391	Heptaprenyl diphosphate synthase component I; Region: Hpre_diP_synt_I; pfam07456
1088720006392	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1088720006393	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1088720006394	substrate binding pocket [chemical binding]; other site
1088720006395	chain length determination region; other site
1088720006396	substrate-Mg2+ binding site; other site
1088720006397	catalytic residues [active]
1088720006398	aspartate-rich region 1; other site
1088720006399	active site lid residues [active]
1088720006400	aspartate-rich region 2; other site
1088720006401	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1088720006402	Calcineurin-like phosphoesterase superfamily domain; Region: Metallophos_2; pfam12850
1088720006403	active site
1088720006404	metal binding site [ion binding]; metal-binding site
1088720006405	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
1088720006406	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1088720006407	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1088720006408	Walker A/P-loop; other site
1088720006409	ATP binding site [chemical binding]; other site
1088720006410	Q-loop/lid; other site
1088720006411	ABC transporter signature motif; other site
1088720006412	Walker B; other site
1088720006413	D-loop; other site
1088720006414	H-loop/switch region; other site
1088720006415	Predicted dinucleotide-binding enzymes [General function prediction only]; Region: COG2085
1088720006416	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; pfam03807
1088720006417	probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858
1088720006418	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Energy production and conversion]; Region: COG2141
1088720006419	YacP-like NYN domain; Region: NYN_YacP; pfam05991
1088720006420	rRNA methylase, putative, group 3; Region: rRNA_methyl_3; TIGR00186
1088720006421	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
1088720006422	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1088720006423	Ribonuclease III family protein [Replication, recombination, and    repair]; Region: COG1939
1088720006424	active site
1088720006425	metal binding site [ion binding]; metal-binding site
1088720006426	dimerization interface [polypeptide binding]; other site
1088720006427	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1088720006428	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1088720006429	active site
1088720006430	HIGH motif; other site
1088720006431	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1088720006432	KMSKS motif; other site
1088720006433	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1088720006434	tRNA binding surface [nucleotide binding]; other site
1088720006435	anticodon binding site; other site
1088720006436	FAD binding domain; Region: FAD_binding_4; pfam01565
1088720006437	glycolate oxidase, subunit GlcD; Region: glcD; TIGR00387
1088720006438	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
1088720006439	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1088720006440	active site
1088720006441	HIGH motif; other site
1088720006442	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1088720006443	active site
1088720006444	KMSKS motif; other site
1088720006445	Putative membrane peptidase family (DUF2324); Region: DUF2324; pfam10086
1088720006446	Predicted membrane protein [General function prediction only]; Region: COG4194
1088720006447	Predicted transcriptional regulators [Transcription]; Region: COG1725
1088720006448	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1088720006449	DNA-binding site [nucleotide binding]; DNA binding site
1088720006450	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
1088720006451	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720006452	Walker A/P-loop; other site
1088720006453	ATP binding site [chemical binding]; other site
1088720006454	Q-loop/lid; other site
1088720006455	ABC transporter signature motif; other site
1088720006456	Walker B; other site
1088720006457	D-loop; other site
1088720006458	H-loop/switch region; other site
1088720006459	KxYKxGKxW signal peptide; Region: KxYKxGKxW; TIGR03715
1088720006460	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1088720006461	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1088720006462	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1088720006463	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1088720006464	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
1088720006465	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
1088720006466	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1088720006467	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720006468	Walker A/P-loop; other site
1088720006469	ATP binding site [chemical binding]; other site
1088720006470	Q-loop/lid; other site
1088720006471	ABC transporter signature motif; other site
1088720006472	Walker B; other site
1088720006473	D-loop; other site
1088720006474	H-loop/switch region; other site
1088720006475	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1088720006476	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1088720006477	non-specific DNA binding site [nucleotide binding]; other site
1088720006478	salt bridge; other site
1088720006479	sequence-specific DNA binding site [nucleotide binding]; other site
1088720006480	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
1088720006481	Integral membrane protein (PIN domain superfamily) [General function prediction only]; Region: COG4956
1088720006482	PIN domain of Thermus Thermophilus Hb8, uncharacterized Bacillus subtilis YacL, and other bacterial homologs; Region: PIN_YacL; cd09877
1088720006483	putative active site [active]
1088720006484	DNA repair protein RadA; Provisional; Region: PRK11823
1088720006485	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
1088720006486	Walker A motif/ATP binding site; other site
1088720006487	ATP binding site [chemical binding]; other site
1088720006488	Walker B motif; other site
1088720006489	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1088720006490	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1088720006491	trimer interface [polypeptide binding]; other site
1088720006492	active site
1088720006493	Predicted acetyltransferase [General function prediction only]; Region: COG2388
1088720006494	Peptidase C1B subfamily (MEROPS database nomenclature); composed of eukaryotic bleomycin hydrolases (BH) and bacterial aminopeptidases C (pepC). The proteins of this subfamily contain a large insert relative to the C1A peptidase (papain) subfamily. BH is...; Region: Peptidase_C1B; cd00585
1088720006495	trimer interface [polypeptide binding]; other site
1088720006496	active site
1088720006497	Peptidase C1B subfamily (MEROPS database nomenclature); composed of eukaryotic bleomycin hydrolases (BH) and bacterial aminopeptidases C (pepC). The proteins of this subfamily contain a large insert relative to the C1A peptidase (papain) subfamily. BH is...; Region: Peptidase_C1B; cd00585
1088720006498	trimer interface [polypeptide binding]; other site
1088720006499	active site
1088720006500	G bulge; other site
1088720006501	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
1088720006502	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1088720006503	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1088720006504	Walker A/P-loop; other site
1088720006505	ATP binding site [chemical binding]; other site
1088720006506	Q-loop/lid; other site
1088720006507	ABC transporter signature motif; other site
1088720006508	Walker B; other site
1088720006509	D-loop; other site
1088720006510	H-loop/switch region; other site
1088720006511	K+ potassium transporter; Region: K_trans; pfam02705
1088720006512	pyruvate phosphate dikinase; Provisional; Region: PRK09279
1088720006513	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
1088720006514	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1088720006515	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1088720006516	HTH domain; Region: HTH_11; pfam08279
1088720006517	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
1088720006518	FOG: CBS domain [General function prediction only]; Region: COG0517
1088720006519	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1088720006520	catalytic core [active]
1088720006521	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1088720006522	Bacterial low temperature requirement A protein (LtrA); Region: LtrA; cl01754
1088720006523	L-lactate oxidase; Region: L_lactate_ox; TIGR02708
1088720006524	L-Lactate oxidase (LOX) FMN-binding domain. LOX is a member of the family of FMN-containing alpha-hydroxyacid oxidases and catalyzes the oxidation of l-lactate using molecular oxygen to generate pyruvate and H2O2.  This family occurs in both prokaryotes...; Region: LOX_like_FMN; cd04737
1088720006525	teramer interface [polypeptide binding]; other site
1088720006526	active site
1088720006527	FMN binding site [chemical binding]; other site
1088720006528	catalytic residues [active]
1088720006529	CsbD-like; Region: CsbD; pfam05532
1088720006530	phosphopentomutase; Provisional; Region: PRK05362
1088720006531	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
1088720006532	benzoate transport; Region: 2A0115; TIGR00895
1088720006533	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720006534	putative substrate translocation pore; other site
1088720006535	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
1088720006536	benzoate transport; Region: 2A0115; TIGR00895
1088720006537	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720006538	putative substrate translocation pore; other site
1088720006539	Purine catabolism regulatory protein-like family; Region: PucR; pfam07905
1088720006540	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1088720006541	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720006542	H+ Antiporter protein; Region: 2A0121; TIGR00900
1088720006543	putative substrate translocation pore; other site
1088720006544	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
1088720006545	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
1088720006546	putative catalytic cysteine [active]
1088720006547	gamma-glutamyl kinase; Provisional; Region: PRK05429
1088720006548	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
1088720006549	nucleotide binding site [chemical binding]; other site
1088720006550	homotetrameric interface [polypeptide binding]; other site
1088720006551	putative phosphate binding site [ion binding]; other site
1088720006552	putative allosteric binding site; other site
1088720006553	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1088720006554	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1088720006555	FtsX-like permease family; Region: FtsX; pfam02687
1088720006556	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1088720006557	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1088720006558	Walker A/P-loop; other site
1088720006559	ATP binding site [chemical binding]; other site
1088720006560	Q-loop/lid; other site
1088720006561	ABC transporter signature motif; other site
1088720006562	Walker B; other site
1088720006563	D-loop; other site
1088720006564	H-loop/switch region; other site
1088720006565	Sortase C (SrtC) or subfamily-3 sortases are membrane cysteine transpeptidases found in Gram-positive bacteria that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. This involves a transpeptidation reaction in which the...; Region: Sortase_C_3; cd05827
1088720006566	active site
1088720006567	catalytic site [active]
1088720006568	fimbrial isopeptide formation D2 domain; Region: RrgB_K2N_iso_D2; TIGR04226
1088720006569	Cna protein B-type domain; Region: Cna_B; pfam05738
1088720006570	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1088720006571	Cna protein B-type domain; Region: Cna_B; pfam05738
1088720006572	Uncharacterized conserved protein (DUF2075); Region: DUF2075; pfam09848
1088720006573	Uncharacterized conserved protein [Function unknown]; Region: COG3410
1088720006574	Protein of unknown function (DUF2974); Region: DUF2974; pfam11187
1088720006575	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1088720006576	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1088720006577	non-specific DNA binding site [nucleotide binding]; other site
1088720006578	salt bridge; other site
1088720006579	sequence-specific DNA binding site [nucleotide binding]; other site
1088720006580	Predicted transcriptional regulators [Transcription]; Region: COG1695
1088720006581	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1088720006582	hypothetical protein; Validated; Region: PRK07668
1088720006583	hypothetical protein; Validated; Region: PRK07668
1088720006584	Enterocin A Immunity; Region: EntA_Immun; pfam08951
1088720006585	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1088720006586	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1088720006587	active site
1088720006588	catalytic tetrad [active]
1088720006589	Uncharacterized conserved protein [Function unknown]; Region: COG2966
1088720006590	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
1088720006591	Protein of unknown function (DUF3815); Region: DUF3815; pfam12821
1088720006592	bacteriocin secretion accessory protein; Region: bacteriocin_acc; TIGR01000
1088720006593	HlyD family secretion protein; Region: HlyD_3; pfam13437
1088720006594	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39B; cd02418
1088720006595	ABC-type bacteriocin transporter; Region: bacteriocin_ABC; TIGR01193
1088720006596	putative active site [active]
1088720006597	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1088720006598	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720006599	Walker A/P-loop; other site
1088720006600	ATP binding site [chemical binding]; other site
1088720006601	Q-loop/lid; other site
1088720006602	ABC transporter signature motif; other site
1088720006603	Walker B; other site
1088720006604	D-loop; other site
1088720006605	H-loop/switch region; other site
1088720006606	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1088720006607	ATP binding site [chemical binding]; other site
1088720006608	Mg2+ binding site [ion binding]; other site
1088720006609	G-X-G motif; other site
1088720006610	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1088720006611	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl17736
1088720006612	phosphorylation site [posttranslational modification]
1088720006613	intermolecular recognition site; other site
1088720006614	LytTr DNA-binding domain; Region: LytTR; pfam04397
1088720006615	CAAX protease self-immunity; Region: Abi; pfam02517
1088720006616	Rrf2 family protein; Region: rrf2_super; TIGR00738
1088720006617	Transcriptional regulator; Region: Rrf2; pfam02082
1088720006618	Transcriptional regulator; Region: Rrf2; cl17282
1088720006619	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720006620	putative substrate translocation pore; other site
1088720006621	Enterocin A Immunity; Region: EntA_Immun; pfam08951
1088720006622	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1088720006623	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1088720006624	active site
1088720006625	catalytic tetrad [active]
1088720006626	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
1088720006627	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1088720006628	NAD(P) binding site [chemical binding]; other site
1088720006629	active site
1088720006630	Old yellow enzyme (OYE)-related FMN binding domain, group 4.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as...; Region: OYE_like_4_FMN; cd04735
1088720006631	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1088720006632	putative active site [active]
1088720006633	putative FMN binding site [chemical binding]; other site
1088720006634	putative substrate binding site [chemical binding]; other site
1088720006635	putative catalytic residue [active]
1088720006636	Short C-terminal domain; Region: SHOCT; pfam09851
1088720006637	fumarate hydratase; Reviewed; Region: fumC; PRK00485
1088720006638	Class II fumarases; Region: Fumarase_classII; cd01362
1088720006639	active site
1088720006640	tetramer interface [polypeptide binding]; other site
1088720006641	manganese transport protein MntH; Reviewed; Region: PRK00701
1088720006642	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
1088720006643	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
1088720006644	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
1088720006645	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1088720006646	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1088720006647	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1088720006648	motif II; other site
1088720006649	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1088720006650	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720006651	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1088720006652	putative substrate translocation pore; other site
1088720006653	multicopper oxidase; Provisional; Region: PRK10965
1088720006654	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1088720006655	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
1088720006656	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1088720006657	Cation efflux family; Region: Cation_efflux; cl00316
1088720006658	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1088720006659	dimerization interface [polypeptide binding]; other site
1088720006660	putative DNA binding site [nucleotide binding]; other site
1088720006661	putative Zn2+ binding site [ion binding]; other site
1088720006662	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
1088720006663	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
1088720006664	metal binding site [ion binding]; metal-binding site
1088720006665	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1088720006666	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1088720006667	ABC-ATPase subunit  interface; other site
1088720006668	dimer interface [polypeptide binding]; other site
1088720006669	putative PBP binding regions; other site
1088720006670	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
1088720006671	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1088720006672	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
1088720006673	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1088720006674	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
1088720006675	intersubunit interface [polypeptide binding]; other site
1088720006676	atypical (a) SDRs, subgroup 6; Region: SDR_a6; cd05267
1088720006677	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1088720006678	putative NAD(P) binding site [chemical binding]; other site
1088720006679	Metal binding protein TroA_b.  These proteins are predicted to function as initial receptors in ABC transport of metal ions.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding...; Region: TroA_b; cd01020
1088720006680	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
1088720006681	metal binding site [ion binding]; metal-binding site
1088720006682	CrcB-like protein; Region: CRCB; cl09114
1088720006683	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1088720006684	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720006685	Alpha-L-rhamnosidase N-terminal domain; Region: Bac_rhamnosid_N; pfam08531
1088720006686	Bacterial alpha-L-rhamnosidase; Region: Bac_rhamnosid; pfam05592
1088720006687	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
1088720006688	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1088720006689	substrate binding pocket [chemical binding]; other site
1088720006690	membrane-bound complex binding site; other site
1088720006691	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
1088720006692	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1088720006693	Subfamily of fatty acid CoA ligase (FACL) similar to Fum10p of Gibberella moniliformis; Region: FACL_fum10p_like; cd05926
1088720006694	acyl-activating enzyme (AAE) consensus motif; other site
1088720006695	acyl-activating enzyme (AAE) consensus motif; other site
1088720006696	putative AMP binding site [chemical binding]; other site
1088720006697	putative active site [active]
1088720006698	putative CoA binding site [chemical binding]; other site
1088720006699	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1088720006700	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720006701	aliphatic sulfonates transport ATP-binding subunit; Provisional; Region: ssuB; PRK11247
1088720006702	Walker A/P-loop; other site
1088720006703	ATP binding site [chemical binding]; other site
1088720006704	Q-loop/lid; other site
1088720006705	ABC transporter signature motif; other site
1088720006706	Walker B; other site
1088720006707	D-loop; other site
1088720006708	H-loop/switch region; other site
1088720006709	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1088720006710	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1088720006711	putative PBP binding loops; other site
1088720006712	dimer interface [polypeptide binding]; other site
1088720006713	ABC-ATPase subunit interface; other site
1088720006714	Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only]; Region: COG3382
1088720006715	B3/4 domain; Region: B3_4; pfam03483
1088720006716	PemK-like protein; Region: PemK; pfam02452
1088720006717	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1088720006718	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720006719	Walker A/P-loop; other site
1088720006720	ATP binding site [chemical binding]; other site
1088720006721	Q-loop/lid; other site
1088720006722	ABC transporter signature motif; other site
1088720006723	Walker B; other site
1088720006724	D-loop; other site
1088720006725	H-loop/switch region; other site
1088720006726	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1088720006727	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720006728	Walker A/P-loop; other site
1088720006729	ATP binding site [chemical binding]; other site
1088720006730	Q-loop/lid; other site
1088720006731	ABC transporter signature motif; other site
1088720006732	Walker B; other site
1088720006733	D-loop; other site
1088720006734	H-loop/switch region; other site
1088720006735	H+ Antiporter protein; Region: 2A0121; TIGR00900
1088720006736	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720006737	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1088720006738	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1088720006739	23S rRNA interface [nucleotide binding]; other site
1088720006740	L3 interface [polypeptide binding]; other site
1088720006741	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1088720006742	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1088720006743	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1088720006744	FtsX-like permease family; Region: FtsX; pfam02687
1088720006745	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1088720006746	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1088720006747	Walker A/P-loop; other site
1088720006748	ATP binding site [chemical binding]; other site
1088720006749	Q-loop/lid; other site
1088720006750	ABC transporter signature motif; other site
1088720006751	Walker B; other site
1088720006752	D-loop; other site
1088720006753	H-loop/switch region; other site
1088720006754	Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA; Region: HTH_TipAL-Mta; cd01106
1088720006755	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1088720006756	DNA binding residues [nucleotide binding]
1088720006757	dimer interface [polypeptide binding]; other site
1088720006758	TipAS antibiotic-recognition domain; Region: TipAS; pfam07739
1088720006759	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
1088720006760	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1088720006761	dimerization interface 3.5A [polypeptide binding]; other site
1088720006762	active site
1088720006763	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
1088720006764	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13634
1088720006765	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1088720006766	Walker A/P-loop; other site
1088720006767	ATP binding site [chemical binding]; other site
1088720006768	Q-loop/lid; other site
1088720006769	ABC transporter signature motif; other site
1088720006770	Walker B; other site
1088720006771	D-loop; other site
1088720006772	H-loop/switch region; other site
1088720006773	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13635
1088720006774	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1088720006775	Walker A/P-loop; other site
1088720006776	ATP binding site [chemical binding]; other site
1088720006777	Q-loop/lid; other site
1088720006778	ABC transporter signature motif; other site
1088720006779	Walker B; other site
1088720006780	D-loop; other site
1088720006781	H-loop/switch region; other site
1088720006782	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
1088720006783	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
1088720006784	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1088720006785	alphaNTD homodimer interface [polypeptide binding]; other site
1088720006786	alphaNTD - beta interaction site [polypeptide binding]; other site
1088720006787	alphaNTD - beta' interaction site [polypeptide binding]; other site
1088720006788	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1088720006789	30S ribosomal protein S11; Validated; Region: PRK05309
1088720006790	Ribosomal protein S13 [Translation, ribosomal structure and biogenesis]; Region: RpsM; COG0099
1088720006791	30S ribosomal protein S13; Region: bact_S13; TIGR03631
1088720006792	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1088720006793	rRNA binding site [nucleotide binding]; other site
1088720006794	predicted 30S ribosome binding site; other site
1088720006795	adenylate kinase; Reviewed; Region: adk; PRK00279
1088720006796	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1088720006797	AMP-binding site [chemical binding]; other site
1088720006798	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1088720006799	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1088720006800	SecY translocase; Region: SecY; pfam00344
1088720006801	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1088720006802	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
1088720006803	23S rRNA binding site [nucleotide binding]; other site
1088720006804	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
1088720006805	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1088720006806	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1088720006807	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1088720006808	5S rRNA interface [nucleotide binding]; other site
1088720006809	L27 interface [polypeptide binding]; other site
1088720006810	23S rRNA interface [nucleotide binding]; other site
1088720006811	L5 interface [polypeptide binding]; other site
1088720006812	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1088720006813	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1088720006814	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1088720006815	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1088720006816	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1088720006817	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1088720006818	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1088720006819	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
1088720006820	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1088720006821	RNA binding site [nucleotide binding]; other site
1088720006822	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
1088720006823	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1088720006824	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1088720006825	23S rRNA interface [nucleotide binding]; other site
1088720006826	putative translocon interaction site; other site
1088720006827	signal recognition particle (SRP54) interaction site; other site
1088720006828	L23 interface [polypeptide binding]; other site
1088720006829	trigger factor interaction site; other site
1088720006830	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1088720006831	23S rRNA interface [nucleotide binding]; other site
1088720006832	5S rRNA interface [nucleotide binding]; other site
1088720006833	putative antibiotic binding site [chemical binding]; other site
1088720006834	L25 interface [polypeptide binding]; other site
1088720006835	L27 interface [polypeptide binding]; other site
1088720006836	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1088720006837	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1088720006838	G-X-X-G motif; other site
1088720006839	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1088720006840	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1088720006841	putative translocon binding site; other site
1088720006842	protein-rRNA interface [nucleotide binding]; other site
1088720006843	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
1088720006844	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1088720006845	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1088720006846	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1088720006847	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1088720006848	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1088720006849	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
1088720006850	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1088720006851	phosphate-starvation-inducible protein PsiE; Provisional; Region: PRK02833
1088720006852	peroxiredoxin; Region: AhpC; TIGR03137
1088720006853	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1088720006854	dimer interface [polypeptide binding]; other site
1088720006855	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1088720006856	catalytic triad [active]
1088720006857	peroxidatic and resolving cysteines [active]
1088720006858	Predicted transcriptional regulator [Transcription]; Region: COG2378
1088720006859	WYL domain; Region: WYL; pfam13280
1088720006860	elongation factor G; Reviewed; Region: PRK12739
1088720006861	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1088720006862	G1 box; other site
1088720006863	putative GEF interaction site [polypeptide binding]; other site
1088720006864	GTP/Mg2+ binding site [chemical binding]; other site
1088720006865	Switch I region; other site
1088720006866	G2 box; other site
1088720006867	G3 box; other site
1088720006868	Switch II region; other site
1088720006869	G4 box; other site
1088720006870	G5 box; other site
1088720006871	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1088720006872	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1088720006873	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1088720006874	30S ribosomal protein S7; Validated; Region: PRK05302
1088720006875	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
1088720006876	S17 interaction site [polypeptide binding]; other site
1088720006877	S8 interaction site; other site
1088720006878	16S rRNA interaction site [nucleotide binding]; other site
1088720006879	streptomycin interaction site [chemical binding]; other site
1088720006880	23S rRNA interaction site [nucleotide binding]; other site
1088720006881	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
1088720006882	DNA-directed RNA polymerase subunit beta'; Provisional; Region: PRK00566
1088720006883	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
1088720006884	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
1088720006885	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
1088720006886	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
1088720006887	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1088720006888	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1088720006889	DNA binding site [nucleotide binding]
1088720006890	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1088720006891	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
1088720006892	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1088720006893	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
1088720006894	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1088720006895	RPB1 interaction site [polypeptide binding]; other site
1088720006896	RPB10 interaction site [polypeptide binding]; other site
1088720006897	RPB11 interaction site [polypeptide binding]; other site
1088720006898	RPB3 interaction site [polypeptide binding]; other site
1088720006899	RPB12 interaction site [polypeptide binding]; other site
1088720006900	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
1088720006901	Clp amino terminal domain; Region: Clp_N; pfam02861
1088720006902	Clp amino terminal domain; Region: Clp_N; pfam02861
1088720006903	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1088720006904	Walker A motif; other site
1088720006905	ATP binding site [chemical binding]; other site
1088720006906	Walker B motif; other site
1088720006907	arginine finger; other site
1088720006908	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1088720006909	Walker A motif; other site
1088720006910	ATP binding site [chemical binding]; other site
1088720006911	Walker B motif; other site
1088720006912	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1088720006913	Firmicute transcriptional repressor of class III stress genes (CtsR); Region: CtsR; pfam05848
1088720006914	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
1088720006915	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1088720006916	dimer interface [polypeptide binding]; other site
1088720006917	putative anticodon binding site; other site
1088720006918	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1088720006919	motif 1; other site
1088720006920	active site
1088720006921	motif 2; other site
1088720006922	motif 3; other site
1088720006923	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
1088720006924	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1088720006925	FMN binding site [chemical binding]; other site
1088720006926	active site
1088720006927	catalytic residues [active]
1088720006928	substrate binding site [chemical binding]; other site
1088720006929	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
1088720006930	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
1088720006931	dimerization interface [polypeptide binding]; other site
1088720006932	domain crossover interface; other site
1088720006933	redox-dependent activation switch; other site
1088720006934	Protein of unknown function (DUF3139); Region: DUF3139; pfam11337
1088720006935	FtsH Extracellular; Region: FtsH_ext; pfam06480
1088720006936	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
1088720006937	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1088720006938	Walker A motif; other site
1088720006939	ATP binding site [chemical binding]; other site
1088720006940	Walker B motif; other site
1088720006941	arginine finger; other site
1088720006942	Peptidase family M41; Region: Peptidase_M41; pfam01434
1088720006943	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
1088720006944	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1088720006945	active site
1088720006946	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
1088720006947	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1088720006948	Ligand Binding Site [chemical binding]; other site
1088720006949	TilS substrate C-terminal domain; Region: TilS_C; smart00977
1088720006950	hypothetical protein; Provisional; Region: PRK08582
1088720006951	S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692
1088720006952	RNA binding site [nucleotide binding]; other site
1088720006953	Septum formation initiator; Region: DivIC; pfam04977
1088720006954	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1088720006955	RNA binding surface [nucleotide binding]; other site
1088720006956	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1088720006957	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
1088720006958	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
1088720006959	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
1088720006960	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1088720006961	ATP binding site [chemical binding]; other site
1088720006962	putative Mg++ binding site [ion binding]; other site
1088720006963	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1088720006964	nucleotide binding region [chemical binding]; other site
1088720006965	ATP-binding site [chemical binding]; other site
1088720006966	TRCF domain; Region: TRCF; pfam03461
1088720006967	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1088720006968	putative active site [active]
1088720006969	catalytic residue [active]
1088720006970	L-lactate dehydrogenase; Reviewed; Region: ldh; PRK00066
1088720006971	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
1088720006972	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1088720006973	NAD binding site [chemical binding]; other site
1088720006974	dimer interface [polypeptide binding]; other site
1088720006975	substrate binding site [chemical binding]; other site
1088720006976	Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229
1088720006977	Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229
1088720006978	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1088720006979	Predicted transcriptional regulators [Transcription]; Region: COG1695
1088720006980	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1088720006981	Predicted membrane protein [Function unknown]; Region: COG1511
1088720006982	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
1088720006983	YhgE/Pip C-terminal domain; Region: pip_yhgE_Cterm; TIGR03062
1088720006984	Flavodoxin-like fold; Region: Flavodoxin_2; pfam02525
1088720006985	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1088720006986	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
1088720006987	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1088720006988	Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376
1088720006989	glutamate synthase subunit beta; Reviewed; Region: gltD; PRK12810
1088720006990	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1088720006991	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
1088720006992	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
1088720006993	active site
1088720006994	dimer interface [polypeptide binding]; other site
1088720006995	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
1088720006996	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
1088720006997	active site
1088720006998	FMN binding site [chemical binding]; other site
1088720006999	substrate binding site [chemical binding]; other site
1088720007000	3Fe-4S cluster binding site [ion binding]; other site
1088720007001	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
1088720007002	domain interface; other site
1088720007003	QueT transporter; Region: QueT; pfam06177
1088720007004	PemK-like protein; Region: PemK; pfam02452
1088720007005	hypothetical protein; Region: PHA01623
1088720007006	alanine racemase; Reviewed; Region: alr; PRK00053
1088720007007	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
1088720007008	active site
1088720007009	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1088720007010	dimer interface [polypeptide binding]; other site
1088720007011	substrate binding site [chemical binding]; other site
1088720007012	catalytic residues [active]
1088720007013	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
1088720007014	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1088720007015	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1088720007016	ATP binding site [chemical binding]; other site
1088720007017	Mg++ binding site [ion binding]; other site
1088720007018	motif III; other site
1088720007019	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1088720007020	nucleotide binding region [chemical binding]; other site
1088720007021	ATP-binding site [chemical binding]; other site
1088720007022	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
1088720007023	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1088720007024	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1088720007025	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1088720007026	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
1088720007027	Glycosyl hydrolase family 53; Region: Glyco_hydro_53; cl06672
1088720007028	Cna protein B-type domain; Region: Cna_B; pfam05738
1088720007029	Cna protein B-type domain; Region: Cna_B; pfam05738
1088720007030	Cna protein B-type domain; Region: Cna_B; pfam05738
1088720007031	Cna protein B-type domain; Region: Cna_B; pfam05738
1088720007032	Cna protein B-type domain; Region: Cna_B; pfam05738
1088720007033	Cna protein B-type domain; Region: Cna_B; pfam05738
1088720007034	Bacterial protein of unknown function (DUF961); Region: DUF961; pfam06125
1088720007035	Bacterial protein of unknown function (DUF961); Region: DUF961; pfam06125
1088720007036	radical SAM methylthiotransferase, MiaB/RimO family; Region: TIGR00089
1088720007037	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1088720007038	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1088720007039	Walker A motif; other site
1088720007040	ATP binding site [chemical binding]; other site
1088720007041	Walker B motif; other site
1088720007042	arginine finger; other site
1088720007043	Peptidase S8 family domain in Subtilisin-like proteins; Region: Peptidases_S8_Subtilisin_like_2; cd04847
1088720007044	active site
1088720007045	catalytic triad [active]
1088720007046	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1088720007047	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1088720007048	PHP domain; Region: PHP; pfam02811
1088720007049	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
1088720007050	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720007051	Walker A/P-loop; other site
1088720007052	ATP binding site [chemical binding]; other site
1088720007053	AAA domain; Region: AAA_21; pfam13304
1088720007054	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720007055	ABC transporter signature motif; other site
1088720007056	Walker B; other site
1088720007057	D-loop; other site
1088720007058	H-loop/switch region; other site
1088720007059	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1088720007060	non-specific DNA binding site [nucleotide binding]; other site
1088720007061	salt bridge; other site
1088720007062	sequence-specific DNA binding site [nucleotide binding]; other site
1088720007063	Replication initiation factor; Region: Rep_trans; pfam02486
1088720007064	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1088720007065	DNA methylase; Region: N6_N4_Mtase; pfam01555
1088720007066	Antirestriction protein (ArdA); Region: ArdA; cl01953
1088720007067	TcpE family; Region: TcpE; pfam12648
1088720007068	AAA-like domain; Region: AAA_10; pfam12846
1088720007069	NADH dehydrogenase subunit 6; Provisional; Region: ND6; cl17624
1088720007070	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1088720007071	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1088720007072	catalytic residue [active]
1088720007073	NlpC/P60 family; Region: NLPC_P60; pfam00877
1088720007074	Conjugative transposon protein TcpC; Region: TpcC; pfam12642
1088720007075	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
1088720007076	Helix-turn-helix domain; Region: HTH_38; pfam13936
1088720007077	Integrase core domain; Region: rve; pfam00665
1088720007078	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1088720007079	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
1088720007080	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1088720007081	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1088720007082	peptide binding site [polypeptide binding]; other site
1088720007083	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
1088720007084	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
1088720007085	oligomer interface [polypeptide binding]; other site
1088720007086	active site
1088720007087	metal binding site [ion binding]; metal-binding site
1088720007088	potential frameshift: common BLAST hit: gi|191638904|ref|YP_001988070.1| D-aminopeptidase
1088720007089	Peptidase M55, D-aminopeptidase dipeptide-binding protein family; Region: DAP_dppA; cl01007
1088720007090	SxDxEG motif; other site
1088720007091	Peptidase M55, D-aminopeptidase dipeptide-binding protein family; Region: DAP_dppA; cl01007
1088720007092	active site
1088720007093	metal binding site [ion binding]; metal-binding site
1088720007094	homopentamer interface [polypeptide binding]; other site
1088720007095	proline-specific peptidase, Bacillus coagulans-type subfamily; Region: pro_imino_pep_2; TIGR01250
1088720007096	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1088720007097	Protein of unknown function (DUF969); Region: DUF969; pfam06149
1088720007098	Predicted membrane protein [Function unknown]; Region: COG3817
1088720007099	Protein of unknown function (DUF979); Region: DUF979; pfam06166
1088720007100	Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I:  Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from...; Region: Peptidase_C15; cd00501
1088720007101	putative substrate binding pocket [chemical binding]; other site
1088720007102	AC domain interface; other site
1088720007103	catalytic triad [active]
1088720007104	AB domain interface; other site
1088720007105	interchain disulfide; other site
1088720007106	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
1088720007107	Integrase core domain; Region: rve; pfam00665
1088720007108	hypothetical protein; Provisional; Region: PRK10621
1088720007109	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1088720007110	Protein of unknown function (DUF1211); Region: DUF1211; pfam06736
1088720007111	Transposase; Region: HTH_Tnp_1; pfam01527
1088720007112	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1088720007113	HTH domain; Region: HTH_11; pfam08279
1088720007114	Transposase, Mutator family; Region: Transposase_mut; pfam00872
1088720007115	MULE transposase domain; Region: MULE; pfam10551
1088720007116	serine O-acetyltransferase; Region: cysE; TIGR01172
1088720007117	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1088720007118	trimer interface [polypeptide binding]; other site
1088720007119	active site
1088720007120	substrate binding site [chemical binding]; other site
1088720007121	CoA binding site [chemical binding]; other site
1088720007122	cystathionine beta-lyase; Provisional; Region: PRK07671
1088720007123	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1088720007124	homodimer interface [polypeptide binding]; other site
1088720007125	substrate-cofactor binding pocket; other site
1088720007126	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1088720007127	catalytic residue [active]
1088720007128	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1088720007129	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1088720007130	dimer interface [polypeptide binding]; other site
1088720007131	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1088720007132	catalytic residue [active]
1088720007133	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
1088720007134	Helix-turn-helix domain; Region: HTH_38; pfam13936
1088720007135	Integrase core domain; Region: rve; pfam00665
1088720007136	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3316
1088720007137	Integrase core domain; Region: rve; pfam00665
1088720007138	heavy metal translocating P-type ATPase; Region: ATPase-IB_hvy; TIGR01525
1088720007139	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1088720007140	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1088720007141	motif II; other site
1088720007142	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1088720007143	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1088720007144	catalytic residues [active]
1088720007145	Uncharacterized protein YrkD from Bacillus subtilis and related domains; this domain superfamily was previously known as part of DUF156; Region: BsYrkD-like_DUF156; cd10155
1088720007146	putative homodimer interface [polypeptide binding]; other site
1088720007147	putative homotetramer interface [polypeptide binding]; other site
1088720007148	putative metal binding site [ion binding]; other site
1088720007149	putative homodimer-homodimer interface [polypeptide binding]; other site
1088720007150	putative allosteric switch controlling residues; other site
1088720007151	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
1088720007152	Ferritin-like domain; Region: Ferritin; pfam00210
1088720007153	dimerization interface [polypeptide binding]; other site
1088720007154	DPS ferroxidase diiron center [ion binding]; other site
1088720007155	ion pore; other site
1088720007156	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1088720007157	metal-binding site [ion binding]
1088720007158	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
1088720007159	Helix-turn-helix domain; Region: HTH_38; pfam13936
1088720007160	Integrase core domain; Region: rve; pfam00665
1088720007161	asparagine synthetase B; Provisional; Region: asnB; PRK09431
1088720007162	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
1088720007163	active site
1088720007164	dimer interface [polypeptide binding]; other site
1088720007165	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
1088720007166	Ligand Binding Site [chemical binding]; other site
1088720007167	Molecular Tunnel; other site
1088720007168	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3316
1088720007169	Integrase core domain; Region: rve; pfam00665
1088720007170	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1088720007171	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1088720007172	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1088720007173	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1088720007174	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1088720007175	ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system; Region: PQQ_ABC_ATP; TIGR03864
1088720007176	Walker A/P-loop; other site
1088720007177	ATP binding site [chemical binding]; other site
1088720007178	Q-loop/lid; other site
1088720007179	ABC transporter signature motif; other site
1088720007180	Walker B; other site
1088720007181	D-loop; other site
1088720007182	H-loop/switch region; other site
1088720007183	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
1088720007184	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1088720007185	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
1088720007186	Predicted flavoprotein [General function prediction only]; Region: COG0431
1088720007187	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1088720007188	Predicted flavoprotein [General function prediction only]; Region: COG0431
1088720007189	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1088720007190	PAS domain; Region: PAS_10; pfam13596
1088720007191	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
1088720007192	Transposase; Region: DDE_Tnp_ISL3; pfam01610
1088720007193	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1088720007194	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
1088720007195	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
1088720007196	GTPase SAR1 and related small G proteins [General function prediction only]; Region: COG1100
1088720007197	GTP/Mg2+ binding site [chemical binding]; other site
1088720007198	G1 box; other site
1088720007199	G2 box; other site
1088720007200	Switch I region; other site
1088720007201	G3 box; other site
1088720007202	Switch II region; other site
1088720007203	G4 box; other site
1088720007204	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
1088720007205	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
1088720007206	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3316
1088720007207	Integrase core domain; Region: rve; pfam00665
1088720007208	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1088720007209	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cl17257
1088720007210	Helix-turn-helix domain; Region: HTH_17; pfam12728
1088720007211	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1088720007212	active site
1088720007213	DNA binding site [nucleotide binding]
1088720007214	Int/Topo IB signature motif; other site
1088720007215	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
1088720007216	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1088720007217	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1088720007218	hinge; other site
1088720007219	active site
1088720007220	CTP synthetase; Validated; Region: pyrG; PRK05380
1088720007221	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
1088720007222	Catalytic site [active]
1088720007223	active site
1088720007224	UTP binding site [chemical binding]; other site
1088720007225	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
1088720007226	active site
1088720007227	putative oxyanion hole; other site
1088720007228	catalytic triad [active]
1088720007229	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
1088720007230	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1088720007231	Protein of unknown function (DUF1211); Region: DUF1211; cl01421
1088720007232	DNA-directed RNA polymerase delta subunit; Region: RNA_pol_delta; pfam05066
1088720007233	Domain of unknown function (DUF1934); Region: DUF1934; pfam09148
1088720007234	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
1088720007235	HD superfamily phosphohydrolases [General function prediction only]; Region: COG1078
1088720007236	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1088720007237	Zn2+ binding site [ion binding]; other site
1088720007238	Mg2+ binding site [ion binding]; other site
1088720007239	Contains a crystal structure of the Nudix hydrolase from Enterococcus faecalis, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_25; cd04684
1088720007240	nudix motif; other site
1088720007241	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1088720007242	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1088720007243	putative active site [active]
1088720007244	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
1088720007245	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
1088720007246	ASC-1 homology domain, subfamily similar to Pyrococcus furiosus Pf0470. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_PF0470_like; cd06555
1088720007247	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
1088720007248	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1088720007249	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1088720007250	active site
1088720007251	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14354
1088720007252	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
1088720007253	Substrate binding site; other site
1088720007254	Mg++ binding site; other site
1088720007255	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
1088720007256	active site
1088720007257	substrate binding site [chemical binding]; other site
1088720007258	CoA binding site [chemical binding]; other site
1088720007259	VanZ like family; Region: VanZ; pfam04892
1088720007260	RDD family; Region: RDD; pfam06271
1088720007261	pur operon repressor; Provisional; Region: PRK09213
1088720007262	Bacterial purine repressor, N-terminal; Region: PuR_N; pfam09182
1088720007263	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1088720007264	active site
1088720007265	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4619
1088720007266	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720007267	Walker A/P-loop; other site
1088720007268	ATP binding site [chemical binding]; other site
1088720007269	Q-loop/lid; other site
1088720007270	ABC transporter signature motif; other site
1088720007271	Walker B; other site
1088720007272	D-loop; other site
1088720007273	H-loop/switch region; other site
1088720007274	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG0390
1088720007275	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
1088720007276	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1088720007277	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00128
1088720007278	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1088720007279	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1088720007280	Protein of unknown function (DUF1021); Region: DUF1021; pfam06257
1088720007281	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1088720007282	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1088720007283	S-adenosylmethionine binding site [chemical binding]; other site
1088720007284	ribonuclease M5; Region: 5S_RNA_mat_M5; TIGR00334
1088720007285	TOPRIM_ RNase M5_like: The topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain found in Ribonuclease M5: (RNase M5) and other small primase-like proteins from bacteria and archaea.  RNase M5 catalyzes the maturation of 5S rRNA in low...; Region: TOPRIM_RNase_M5_like; cd01027
1088720007286	putative active site [active]
1088720007287	putative metal binding site [ion binding]; other site
1088720007288	Domain of unknown function (DUF4093); Region: DUF4093; pfam13331
1088720007289	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1088720007290	active site
1088720007291	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cl00163
1088720007292	active site
1088720007293	phosphorylation site [posttranslational modification]
1088720007294	Class I aldolases; Region: Aldolase_Class_I; cl17187
1088720007295	Aldose 1-epimerase, similar to Lactococcus lactis lacX; Region: Aldose_epim_lacX; cd09024
1088720007296	active site
1088720007297	catalytic residues [active]
1088720007298	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1088720007299	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1088720007300	active site
1088720007301	phosphorylation site [posttranslational modification]
1088720007302	intermolecular recognition site; other site
1088720007303	dimerization interface [polypeptide binding]; other site
1088720007304	LytTr DNA-binding domain; Region: LytTR; pfam04397
1088720007305	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
1088720007306	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
1088720007307	ATP binding site [chemical binding]; other site
1088720007308	Mg2+ binding site [ion binding]; other site
1088720007309	G-X-G motif; other site
1088720007310	Transmembrane protein 231; Region: TM231; pfam10149
1088720007311	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720007312	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1088720007313	Walker A/P-loop; other site
1088720007314	ATP binding site [chemical binding]; other site
1088720007315	Q-loop/lid; other site
1088720007316	ABC transporter signature motif; other site
1088720007317	Walker B; other site
1088720007318	D-loop; other site
1088720007319	H-loop/switch region; other site
1088720007320	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1088720007321	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720007322	Walker A/P-loop; other site
1088720007323	ATP binding site [chemical binding]; other site
1088720007324	Q-loop/lid; other site
1088720007325	ABC transporter signature motif; other site
1088720007326	Walker B; other site
1088720007327	D-loop; other site
1088720007328	H-loop/switch region; other site
1088720007329	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1088720007330	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1088720007331	non-specific DNA binding site [nucleotide binding]; other site
1088720007332	salt bridge; other site
1088720007333	sequence-specific DNA binding site [nucleotide binding]; other site
1088720007334	methionyl-tRNA synthetase; Reviewed; Region: PRK12267
1088720007335	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
1088720007336	active site
1088720007337	HIGH motif; other site
1088720007338	KMSKS motif; other site
1088720007339	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1088720007340	tRNA binding surface [nucleotide binding]; other site
1088720007341	anticodon binding site; other site
1088720007342	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
1088720007343	dimer interface [polypeptide binding]; other site
1088720007344	putative tRNA-binding site [nucleotide binding]; other site
1088720007345	proline-specific peptidase, Bacillus coagulans-type subfamily; Region: pro_imino_pep_2; TIGR01250
1088720007346	Protein of unknown function DUF72; Region: DUF72; pfam01904
1088720007347	MutT homolog-1 (MTH1) is a member of the Nudix hydrolase superfamily. MTH1, the mammalian counterpart of MutT, hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP and 2-hydroxy-ATP, to monophosphates, thereby preventing the...; Region: MTH1; cd03427
1088720007348	putative active site [active]
1088720007349	nucleotide binding site [chemical binding]; other site
1088720007350	nudix motif; other site
1088720007351	putative metal binding site [ion binding]; other site
1088720007352	NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195
1088720007353	L-lactate dehydrogenase; Region: L-LDH-NAD; TIGR01771
1088720007354	LDH/MDH dimer interface [polypeptide binding]; other site
1088720007355	NAD(P) binding site [chemical binding]; other site
1088720007356	substrate binding site [chemical binding]; other site
1088720007357	Protein of unknown function (DUF1211); Region: DUF1211; cl01421
1088720007358	NAD-dependent deacetylase; Provisional; Region: PRK00481
1088720007359	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
1088720007360	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
1088720007361	substrate binding site [chemical binding]; other site
1088720007362	Predicted secreted protein [Function unknown]; Region: COG4086
1088720007363	Protein of unknown function (DUF1002); Region: DUF1002; pfam06207
1088720007364	exopolyphosphatase; Region: exo_poly_only; TIGR03706
1088720007365	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1088720007366	polyphosphate kinase; Provisional; Region: PRK05443
1088720007367	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
1088720007368	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
1088720007369	Catalytic C-terminal domain, first repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C1_like; cd09165
1088720007370	putative domain interface [polypeptide binding]; other site
1088720007371	putative active site [active]
1088720007372	catalytic site [active]
1088720007373	Catalytic C-terminal domain, second repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C2_like; cd09168
1088720007374	putative domain interface [polypeptide binding]; other site
1088720007375	putative active site [active]
1088720007376	catalytic site [active]
1088720007377	exopolyphosphatase; Region: exo_poly_only; TIGR03706
1088720007378	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1088720007379	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1088720007380	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1088720007381	active site
1088720007382	catalytic tetrad [active]
1088720007383	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1088720007384	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1088720007385	S-adenosylmethionine binding site [chemical binding]; other site
1088720007386	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1088720007387	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1088720007388	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1088720007389	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; Region: MATE_yoeA_like; cd13138
1088720007390	Repair protein; Region: Repair_PSII; pfam04536
1088720007391	Uncharacterized conserved protein [Function unknown]; Region: LemA; COG1704
1088720007392	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1088720007393	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1088720007394	active site
1088720007395	HIGH motif; other site
1088720007396	dimer interface [polypeptide binding]; other site
1088720007397	KMSKS motif; other site
1088720007398	H+ Antiporter protein; Region: 2A0121; TIGR00900
1088720007399	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes [Energy production and conversion]; Region: Lpd; COG1249
1088720007400	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1088720007401	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1088720007402	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
1088720007403	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720007404	Walker A/P-loop; other site
1088720007405	ATP binding site [chemical binding]; other site
1088720007406	Q-loop/lid; other site
1088720007407	ABC transporter signature motif; other site
1088720007408	Walker B; other site
1088720007409	D-loop; other site
1088720007410	H-loop/switch region; other site
1088720007411	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1088720007412	dimer interface [polypeptide binding]; other site
1088720007413	conserved gate region; other site
1088720007414	ABC-ATPase subunit interface; other site
1088720007415	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
1088720007416	Superfamily I DNA and RNA helicases [General function prediction only]; Region: COG3973
1088720007417	Part of AAA domain; Region: AAA_19; pfam13245
1088720007418	Family description; Region: UvrD_C_2; pfam13538
1088720007419	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1088720007420	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1088720007421	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1088720007422	dimerization interface [polypeptide binding]; other site
1088720007423	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
1088720007424	C4-dicarboxylate transporters of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family; Region: TDT_C4-dicarb_trans; cd09325
1088720007425	gating phenylalanine in ion channel; other site
1088720007426	ABC-2 type transporter; Region: ABC2_membrane; cl17235
1088720007427	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
1088720007428	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720007429	Walker A/P-loop; other site
1088720007430	ATP binding site [chemical binding]; other site
1088720007431	Q-loop/lid; other site
1088720007432	ABC transporter signature motif; other site
1088720007433	Walker B; other site
1088720007434	D-loop; other site
1088720007435	H-loop/switch region; other site
1088720007436	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1088720007437	putative DNA binding site [nucleotide binding]; other site
1088720007438	dimerization interface [polypeptide binding]; other site
1088720007439	putative Zn2+ binding site [ion binding]; other site
1088720007440	CAAX protease self-immunity; Region: Abi; pfam02517
1088720007441	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1088720007442	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1088720007443	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1088720007444	Walker A/P-loop; other site
1088720007445	ATP binding site [chemical binding]; other site
1088720007446	Q-loop/lid; other site
1088720007447	ABC transporter signature motif; other site
1088720007448	Walker B; other site
1088720007449	D-loop; other site
1088720007450	H-loop/switch region; other site
1088720007451	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
1088720007452	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215
1088720007453	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1088720007454	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
1088720007455	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720007456	Walker A/P-loop; other site
1088720007457	ATP binding site [chemical binding]; other site
1088720007458	Q-loop/lid; other site
1088720007459	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1088720007460	Excinuclease ATPase subunit [DNA replication, recombination, and repair]; Region: UvrA; COG0178
1088720007461	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720007462	ABC transporter signature motif; other site
1088720007463	Walker B; other site
1088720007464	D-loop; other site
1088720007465	H-loop/switch region; other site
1088720007466	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720007467	Walker A/P-loop; other site
1088720007468	ATP binding site [chemical binding]; other site
1088720007469	Q-loop/lid; other site
1088720007470	ABC transporter signature motif; other site
1088720007471	Walker B; other site
1088720007472	D-loop; other site
1088720007473	H-loop/switch region; other site
1088720007474	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1088720007475	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1088720007476	active site
1088720007477	catalytic tetrad [active]
1088720007478	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
1088720007479	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1088720007480	active site
1088720007481	motif I; other site
1088720007482	motif II; other site
1088720007483	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1088720007484	Protein of unknown function (DUF1275); Region: DUF1275; pfam06912
1088720007485	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1088720007486	catalytic core [active]
1088720007487	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cl11399
1088720007488	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1088720007489	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1088720007490	active site
1088720007491	motif I; other site
1088720007492	motif II; other site
1088720007493	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1088720007494	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
1088720007495	RNA/DNA hybrid binding site [nucleotide binding]; other site
1088720007496	active site
1088720007497	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1088720007498	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1088720007499	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1088720007500	dimerization interface [polypeptide binding]; other site
1088720007501	Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436
1088720007502	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1088720007503	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1088720007504	homodimer interface [polypeptide binding]; other site
1088720007505	catalytic residue [active]
1088720007506	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1088720007507	recombinase A; Provisional; Region: recA; PRK09354
1088720007508	hexamer interface [polypeptide binding]; other site
1088720007509	Walker A motif; other site
1088720007510	ATP binding site [chemical binding]; other site
1088720007511	Walker B motif; other site
1088720007512	Protein of unknown function (DUF554); Region: DUF554; pfam04474
1088720007513	putative PTS system  transporter subunits IIBC; Provisional; Region: PRK11404
1088720007514	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1088720007515	active site
1088720007516	P-loop; other site
1088720007517	phosphorylation site [posttranslational modification]
1088720007518	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1088720007519	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1088720007520	active site
1088720007521	phosphorylation site [posttranslational modification]
1088720007522	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
1088720007523	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1088720007524	putative substrate binding site [chemical binding]; other site
1088720007525	putative ATP binding site [chemical binding]; other site
1088720007526	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1088720007527	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1088720007528	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1088720007529	putative active site [active]
1088720007530	glycerol kinase; Provisional; Region: glpK; PRK00047
1088720007531	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
1088720007532	N- and C-terminal domain interface [polypeptide binding]; other site
1088720007533	active site
1088720007534	MgATP binding site [chemical binding]; other site
1088720007535	catalytic site [active]
1088720007536	metal binding site [ion binding]; metal-binding site
1088720007537	glycerol binding site [chemical binding]; other site
1088720007538	homotetramer interface [polypeptide binding]; other site
1088720007539	homodimer interface [polypeptide binding]; other site
1088720007540	FBP binding site [chemical binding]; other site
1088720007541	protein IIAGlc interface [polypeptide binding]; other site
1088720007542	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; pfam01977
1088720007543	3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme metabolism]; Region: UbiX; COG0163
1088720007544	Flavoprotein; Region: Flavoprotein; pfam02441
1088720007545	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1088720007546	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
1088720007547	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1088720007548	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1088720007549	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1088720007550	dimerization interface [polypeptide binding]; other site
1088720007551	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1088720007552	MarR family; Region: MarR_2; pfam12802
1088720007553	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720007554	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1088720007555	putative substrate translocation pore; other site
1088720007556	hypothetical protein; Provisional; Region: PRK06357
1088720007557	intersubunit interface [polypeptide binding]; other site
1088720007558	active site
1088720007559	Zn2+ binding site [ion binding]; other site
1088720007560	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
1088720007561	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
1088720007562	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
1088720007563	active site
1088720007564	P-loop; other site
1088720007565	phosphorylation site [posttranslational modification]
1088720007566	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1088720007567	active site
1088720007568	phosphorylation site [posttranslational modification]
1088720007569	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1088720007570	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1088720007571	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1088720007572	rhamnulose-1-phosphate aldolase; Provisional; Region: PRK03634
1088720007573	intersubunit interface [polypeptide binding]; other site
1088720007574	active site
1088720007575	Zn2+ binding site [ion binding]; other site
1088720007576	L-rhamnose isomerase; Provisional; Region: PRK01076
1088720007577	Domain of unknown function (DUF718); Region: DUF718; cl01281
1088720007578	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
1088720007579	N- and C-terminal domain interface [polypeptide binding]; other site
1088720007580	rhamnulokinase; Region: rhamnulo_kin; TIGR02627
1088720007581	active site
1088720007582	putative catalytic site [active]
1088720007583	metal binding site [ion binding]; metal-binding site
1088720007584	ATP binding site [chemical binding]; other site
1088720007585	carbohydrate binding site [chemical binding]; other site
1088720007586	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720007587	putative substrate translocation pore; other site
1088720007588	Cupin domain; Region: Cupin_2; pfam07883
1088720007589	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1088720007590	Zn-dependent alcohol dehydrogenases, class III [Energy production and conversion]; Region: AdhC; COG1062
1088720007591	Benzyl alcohol dehydrogenase; Region: benzyl_alcohol_DH; cd08278
1088720007592	catalytic Zn binding site [ion binding]; other site
1088720007593	NAD binding site [chemical binding]; other site
1088720007594	structural Zn binding site [ion binding]; other site
1088720007595	Protein of unknown function (DUF1093); Region: DUF1093; pfam06486
1088720007596	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
1088720007597	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1088720007598	Ca binding site [ion binding]; other site
1088720007599	active site
1088720007600	catalytic site [active]
1088720007601	Right handed beta helix region; Region: Beta_helix; pfam13229
1088720007602	Heparinase II/III-like protein; Region: Hepar_II_III; pfam07940
1088720007603	Preprotein translocase subunit; Region: YajC; pfam02699
1088720007604	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
1088720007605	active pocket/dimerization site; other site
1088720007606	active site
1088720007607	phosphorylation site [posttranslational modification]
1088720007608	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
1088720007609	PTS system sorbose-specific iic component; Region: EII-Sor; pfam03609
1088720007610	PTS system sorbose subfamily IIB component; Region: PTSIIB_sorb; pfam03830
1088720007611	active site
1088720007612	phosphorylation site [posttranslational modification]
1088720007613	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
1088720007614	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1088720007615	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1088720007616	Bacterial transcriptional regulator; Region: IclR; pfam01614
1088720007617	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
1088720007618	2-deoxy-D-gluconate 3-dehydrogenase; Provisional; Region: PRK06935
1088720007619	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1088720007620	NADP binding site [chemical binding]; other site
1088720007621	homodimer interface [polypeptide binding]; other site
1088720007622	active site
1088720007623	2-keto-3-deoxy-6-phosphogluconate aldolase [Carbohydrate transport and metabolism]; Region: Eda; COG0800
1088720007624	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1088720007625	active site
1088720007626	intersubunit interface [polypeptide binding]; other site
1088720007627	catalytic residue [active]
1088720007628	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1088720007629	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1088720007630	substrate binding site [chemical binding]; other site
1088720007631	ATP binding site [chemical binding]; other site
1088720007632	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
1088720007633	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1088720007634	active site
1088720007635	dimer interface [polypeptide binding]; other site
1088720007636	Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues; Region: GAG_Lyase; cd01083
1088720007637	substrate binding site [chemical binding]; other site
1088720007638	catalytic residues [active]
1088720007639	Melibiase; Region: Melibiase; pfam02065
1088720007640	PTS system sorbose subfamily IIB component; Region: PTSIIB_sorb; pfam03830
1088720007641	phosphorylation site [posttranslational modification]
1088720007642	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
1088720007643	PTS system sorbose-specific iic component; Region: EII-Sor; pfam03609
1088720007644	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
1088720007645	active pocket/dimerization site; other site
1088720007646	active site
1088720007647	phosphorylation site [posttranslational modification]
1088720007648	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1088720007649	DNA-binding site [nucleotide binding]; DNA binding site
1088720007650	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1088720007651	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1088720007652	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1088720007653	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
1088720007654	Glycoside Hydrolases Family 4; GlvA- and pagL-like glycosidases; Region: GH4_GlvA_pagL_like; cd05298
1088720007655	NAD binding site [chemical binding]; other site
1088720007656	sugar binding site [chemical binding]; other site
1088720007657	divalent metal binding site [ion binding]; other site
1088720007658	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
1088720007659	dimer interface [polypeptide binding]; other site
1088720007660	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
1088720007661	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1088720007662	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1088720007663	active site turn [active]
1088720007664	phosphorylation site [posttranslational modification]
1088720007665	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1088720007666	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1088720007667	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1088720007668	Walker A/P-loop; other site
1088720007669	ATP binding site [chemical binding]; other site
1088720007670	Q-loop/lid; other site
1088720007671	ABC transporter signature motif; other site
1088720007672	Walker B; other site
1088720007673	D-loop; other site
1088720007674	H-loop/switch region; other site
1088720007675	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1088720007676	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1088720007677	non-specific DNA binding site [nucleotide binding]; other site
1088720007678	salt bridge; other site
1088720007679	sequence-specific DNA binding site [nucleotide binding]; other site
1088720007680	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
1088720007681	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1088720007682	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1088720007683	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1088720007684	putative active site [active]
1088720007685	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
1088720007686	HPr interaction site; other site
1088720007687	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1088720007688	active site
1088720007689	phosphorylation site [posttranslational modification]
1088720007690	Protein of unknown function (DUF1341); Region: DUF1341; pfam07071
1088720007691	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1088720007692	dihydroorotase; Provisional; Region: PRK09237
1088720007693	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1088720007694	active site
1088720007695	Domain of unknown function (DUF4310); Region: DUF4310; pfam14187
1088720007696	Domain of unknown function (DUF4311); Region: DUF4311; cl11919
1088720007697	Domain of unknown function (DUF4312); Region: DUF4312; cl11917
1088720007698	Glycine-rich SFCGS; Region: Gly_rich_SFCGS; pfam14272
1088720007699	PRD domain protein EF_0829/AHA_3910; Region: EF_0829; TIGR03582
1088720007700	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1088720007701	HTH domain; Region: HTH_11; pfam08279
1088720007702	HTH domain; Region: HTH_11; pfam08279
1088720007703	PRD domain; Region: PRD; pfam00874
1088720007704	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1088720007705	active site
1088720007706	P-loop; other site
1088720007707	phosphorylation site [posttranslational modification]
1088720007708	Class I aldolases; Region: Aldolase_Class_I; cl17187
1088720007709	catalytic residue [active]
1088720007710	PTS system glucitol/sorbitol-specific IIA component; Region: PTSIIA_gutA; pfam03829
1088720007711	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
1088720007712	PTS system, glucitol/sorbitol-specific, IIBC component; Region: EIIBC-GUT; TIGR00825
1088720007713	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
1088720007714	PTS system enzyme II sorbitol-specific factor; Region: EII-GUT; pfam03608
1088720007715	Glucitol operon activator protein (GutM); Region: GutM; pfam06923
1088720007716	M protein trans-acting positive regulator (MGA) HTH domain; Region: HTH_Mga; pfam08280
1088720007717	HTH domain; Region: HTH_11; pfam08279
1088720007718	PRD domain; Region: PRD; pfam00874
1088720007719	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cl00163
1088720007720	active site
1088720007721	phosphorylation site [posttranslational modification]
1088720007722	sorbitol-6-phosphate 2-dehydrogenase; Provisional; Region: PRK06171
1088720007723	classical (c) SDRs; Region: SDR_c; cd05233
1088720007724	NAD(P) binding site [chemical binding]; other site
1088720007725	active site
1088720007726	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
1088720007727	Plasmid encoded toxin Txe; Region: Plasmid_Txe; cl17389
1088720007728	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1088720007729	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1088720007730	intersubunit interface [polypeptide binding]; other site
1088720007731	active site
1088720007732	Zn2+ binding site [ion binding]; other site
1088720007733	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1088720007734	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1088720007735	active site
1088720007736	motif I; other site
1088720007737	motif II; other site
1088720007738	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1088720007739	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
1088720007740	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
1088720007741	AP (apurinic/apyrimidinic) site pocket; other site
1088720007742	DNA interaction; other site
1088720007743	Metal-binding active site; metal-binding site
1088720007744	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1088720007745	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
1088720007746	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1088720007747	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
1088720007748	active site
1088720007749	dimer interface [polypeptide binding]; other site
1088720007750	magnesium binding site [ion binding]; other site
1088720007751	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1088720007752	active site
1088720007753	P-loop; other site
1088720007754	phosphorylation site [posttranslational modification]
1088720007755	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: PRK12997
1088720007756	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1088720007757	active site
1088720007758	phosphorylation site [posttranslational modification]
1088720007759	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
1088720007760	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1088720007761	KxYKxGKxW signal peptide; Region: KxYKxGKxW; TIGR03715
1088720007762	Peptidase S8 family domain in Streptococcal C5a peptidases; Region: Peptidases_S8_C5a_Peptidase; cd07475
1088720007763	catalytic triad [active]
1088720007764	putative active site [active]
1088720007765	Fn3-like domain (DUF1034); Region: DUF1034; pfam06280
1088720007766	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1088720007767	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1088720007768	nucleotide binding site [chemical binding]; other site
1088720007769	Peptidase family M54, also called archaemetzincins or archaelysins; Region: Peptidase_M54; cl17349
1088720007770	Glycosylasparaginase catalyzes the hydrolysis of the glycosylamide bond of asparagine-linked glycoproteins. This enzyme is an amidase located inside lysosomes. Mutation of this gene in humans causes a genetic disorder known as aspartylglycosaminuria (AGU)...; Region: Glycosylasparaginase; cd04513
1088720007771	active site
1088720007772	dimer interface [polypeptide binding]; other site
1088720007773	catalytic nucleophile [active]
1088720007774	M20 Peptidase Xaa-His dipeptidase (PepV) degrades hydrophobic dipeptides; Region: M20_PepV; cd03888
1088720007775	dipeptidase, putative; Region: dipeptidaselike; TIGR01887
1088720007776	active site
1088720007777	metal binding site [ion binding]; metal-binding site
1088720007778	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1088720007779	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1088720007780	DNA-binding site [nucleotide binding]; DNA binding site
1088720007781	UTRA domain; Region: UTRA; pfam07702
1088720007782	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720007783	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1088720007784	putative substrate translocation pore; other site
1088720007785	Alpha-L-fucosidase; Region: Alpha_L_fucos; cl12119
1088720007786	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
1088720007787	Histone acetyltransferase HPA2 and related acetyltransferases [Transcription / General function prediction only]; Region: WecD; COG0454
1088720007788	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1088720007789	Coenzyme A binding pocket [chemical binding]; other site
1088720007790	Hydrolase of X-linked nucleoside diphosphate N terminal; Region: Nudix_N; pfam12535
1088720007791	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_14; cd04672
1088720007792	nudix motif; other site
1088720007793	Protein of unknown function (DUF3923); Region: DUF3923; pfam13061
1088720007794	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1088720007795	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1088720007796	non-specific DNA binding site [nucleotide binding]; other site
1088720007797	salt bridge; other site
1088720007798	sequence-specific DNA binding site [nucleotide binding]; other site
1088720007799	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
1088720007800	The enzymes of glycosyl hydrolase family 31 (GH31) occur in prokaryotes, eukaryotes, and archaea with a wide range of hydrolytic activities, including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-xylosidase, 6-alpha-glucosyltransferase; Region: GH31; cl11402
1088720007801	active site
1088720007802	catalytic site [active]
1088720007803	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
1088720007804	sugar binding site [chemical binding]; other site
1088720007805	Cohesin domain, interaction partner of dockerin; Region: Type_III_cohesin_like; cd08759
1088720007806	putative dockerin binding interface; other site
1088720007807	ADP-ribose pyrophosphatase [Nucleotide transport and metabolism]; Region: COG1051
1088720007808	nudix motif; other site
1088720007809	Uncharacterized conserved protein [General function prediction only]; Region: COG4111
1088720007810	Isochorismatase family; Region: Isochorismatase; pfam00857
1088720007811	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1088720007812	catalytic triad [active]
1088720007813	conserved cis-peptide bond; other site
1088720007814	nicotinate phosphoribosyltransferase; Validated; Region: PRK09243
1088720007815	Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction...; Region: NAPRTase_A; cd01570
1088720007816	active site
1088720007817	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
1088720007818	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
1088720007819	active site
1088720007820	catalytic site [active]
1088720007821	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
1088720007822	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1088720007823	active site
1088720007824	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1088720007825	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1088720007826	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1088720007827	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1088720007828	dimer interface [polypeptide binding]; other site
1088720007829	conserved gate region; other site
1088720007830	putative PBP binding loops; other site
1088720007831	ABC-ATPase subunit interface; other site
1088720007832	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1088720007833	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1088720007834	dimer interface [polypeptide binding]; other site
1088720007835	conserved gate region; other site
1088720007836	putative PBP binding loops; other site
1088720007837	ABC-ATPase subunit interface; other site
1088720007838	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
1088720007839	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720007840	Walker A/P-loop; other site
1088720007841	ATP binding site [chemical binding]; other site
1088720007842	Q-loop/lid; other site
1088720007843	ABC transporter signature motif; other site
1088720007844	Walker B; other site
1088720007845	D-loop; other site
1088720007846	H-loop/switch region; other site
1088720007847	TOBE domain; Region: TOBE_2; pfam08402
1088720007848	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1088720007849	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
1088720007850	Beta-lactamase; Region: Beta-lactamase; pfam00144
1088720007851	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1088720007852	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
1088720007853	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
1088720007854	putative active site [active]
1088720007855	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1088720007856	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1088720007857	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1088720007858	putative active site [active]
1088720007859	PTS system sorbose subfamily IIB component; Region: PTSIIB_sorb; pfam03830
1088720007860	active site
1088720007861	phosphorylation site [posttranslational modification]
1088720007862	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
1088720007863	PTS system sorbose-specific iic component; Region: EII-Sor; pfam03609
1088720007864	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
1088720007865	putative catalytic site [active]
1088720007866	putative metal binding site [ion binding]; other site
1088720007867	putative phosphate binding site [ion binding]; other site
1088720007868	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
1088720007869	DHH family; Region: DHH; pfam01368
1088720007870	DHHA1 domain; Region: DHHA1; pfam02272
1088720007871	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1088720007872	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1088720007873	active site
1088720007874	catalytic tetrad [active]
1088720007875	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1088720007876	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
1088720007877	DNA binding residues [nucleotide binding]
1088720007878	putative dimer interface [polypeptide binding]; other site
1088720007879	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
1088720007880	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1088720007881	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1088720007882	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1088720007883	Walker A/P-loop; other site
1088720007884	ATP binding site [chemical binding]; other site
1088720007885	Q-loop/lid; other site
1088720007886	ABC transporter signature motif; other site
1088720007887	Walker B; other site
1088720007888	D-loop; other site
1088720007889	H-loop/switch region; other site
1088720007890	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1088720007891	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1088720007892	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1088720007893	Coenzyme A binding pocket [chemical binding]; other site
1088720007894	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1088720007895	D,D-heptose 1,7-bisphosphate phosphatase; Validated; Region: PRK08942
1088720007896	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1088720007897	active site
1088720007898	motif I; other site
1088720007899	motif II; other site
1088720007900	Tyrosine phosphatase family; Region: Y_phosphatase3; pfam13350
1088720007901	Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; Region: PTPc; cl00053
1088720007902	Tyrosine phosphatase family C-terminal region; Region: Y_phosphatase3C; pfam13348
1088720007903	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1088720007904	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1088720007905	Coenzyme A binding pocket [chemical binding]; other site
1088720007906	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
1088720007907	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
1088720007908	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1088720007909	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
1088720007910	transmembrane helices; other site
1088720007911	hypothetical protein; Provisional; Region: PRK11281
1088720007912	Uncharacterized M20 Dipeptidases; Region: M20_dipept_like_4; cd05681
1088720007913	hypothetical protein; Provisional; Region: PRK06446
1088720007914	metal binding site [ion binding]; metal-binding site
1088720007915	dimer interface [polypeptide binding]; other site
1088720007916	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1088720007917	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1088720007918	peptide binding site [polypeptide binding]; other site
1088720007919	Glycosyl hydrolase family 43; Region: GH43_6; cd08985
1088720007920	active site
1088720007921	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1088720007922	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1088720007923	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1088720007924	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1088720007925	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720007926	putative substrate translocation pore; other site
1088720007927	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
1088720007928	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1088720007929	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1088720007930	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1088720007931	Group of bacterial proteins containing an alpha crystallin domain (ACD) similar to Lactobacillus plantarum (Lp) small heat shock proteins (sHsp) HSP 18.5, HSP 18.55 and HSP 19.3. sHsps are molecular chaperones that suppress protein aggregation and...; Region: ACD_LpsHSP_like; cd06471
1088720007932	putative dimer interface [polypeptide binding]; other site
1088720007933	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
1088720007934	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1088720007935	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1088720007936	protein binding site [polypeptide binding]; other site
1088720007937	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
1088720007938	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1088720007939	YycH protein; Region: YycI; pfam09648
1088720007940	YycH protein; Region: YycH; pfam07435
1088720007941	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4863
1088720007942	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: VicK; COG5002
1088720007943	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1088720007944	dimerization interface [polypeptide binding]; other site
1088720007945	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1088720007946	putative active site [active]
1088720007947	heme pocket [chemical binding]; other site
1088720007948	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1088720007949	dimer interface [polypeptide binding]; other site
1088720007950	phosphorylation site [posttranslational modification]
1088720007951	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1088720007952	ATP binding site [chemical binding]; other site
1088720007953	Mg2+ binding site [ion binding]; other site
1088720007954	G-X-G motif; other site
1088720007955	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1088720007956	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1088720007957	active site
1088720007958	phosphorylation site [posttranslational modification]
1088720007959	intermolecular recognition site; other site
1088720007960	dimerization interface [polypeptide binding]; other site
1088720007961	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1088720007962	DNA binding site [nucleotide binding]
1088720007963	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1088720007964	Novel bacterial esterase that cleaves esters on halogenated cyclic compounds; Region: Esterase_713_like; cl17303
1088720007965	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1088720007966	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1088720007967	substrate binding pocket [chemical binding]; other site
1088720007968	membrane-bound complex binding site; other site
1088720007969	hinge residues; other site
1088720007970	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1088720007971	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1088720007972	dimer interface [polypeptide binding]; other site
1088720007973	conserved gate region; other site
1088720007974	putative PBP binding loops; other site
1088720007975	ABC-ATPase subunit interface; other site
1088720007976	argininosuccinate synthase; Provisional; Region: PRK13820
1088720007977	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
1088720007978	ANP binding site [chemical binding]; other site
1088720007979	Substrate Binding Site II [chemical binding]; other site
1088720007980	Substrate Binding Site I [chemical binding]; other site
1088720007981	argininosuccinate lyase; Provisional; Region: PRK00855
1088720007982	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
1088720007983	active sites [active]
1088720007984	tetramer interface [polypeptide binding]; other site
1088720007985	Uncharacterized conserved protein [Function unknown]; Region: COG3589
1088720007986	Bacterial protein of unknown function (DUF871); Region: DUF871; pfam05913
1088720007987	Domain of unknown function (DUF3284); Region: DUF3284; pfam11687
1088720007988	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1088720007989	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1088720007990	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1088720007991	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1088720007992	DNA-binding site [nucleotide binding]; DNA binding site
1088720007993	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
1088720007994	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1088720007995	active site
1088720007996	P-loop; other site
1088720007997	phosphorylation site [posttranslational modification]
1088720007998	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1088720007999	active site
1088720008000	methionine cluster; other site
1088720008001	phosphorylation site [posttranslational modification]
1088720008002	metal binding site [ion binding]; metal-binding site
1088720008003	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1088720008004	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1088720008005	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_18; cd04677
1088720008006	nudix motif; other site
1088720008007	hypothetical protein; Provisional; Region: PRK06762
1088720008008	AAA domain; Region: AAA_33; pfam13671
1088720008009	Isochorismatase family; Region: Isochorismatase; pfam00857
1088720008010	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
1088720008011	catalytic triad [active]
1088720008012	dimer interface [polypeptide binding]; other site
1088720008013	conserved cis-peptide bond; other site
1088720008014	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1088720008015	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720008016	putative substrate translocation pore; other site
1088720008017	Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807
1088720008018	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1088720008019	putative substrate translocation pore; other site
1088720008020	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1088720008021	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1088720008022	active site
1088720008023	catalytic tetrad [active]
1088720008024	Domain of unknown function (DUF956); Region: DUF956; pfam06115
1088720008025	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
1088720008026	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
1088720008027	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
1088720008028	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1088720008029	active pocket/dimerization site; other site
1088720008030	active site
1088720008031	phosphorylation site [posttranslational modification]
1088720008032	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1088720008033	active site
1088720008034	phosphorylation site [posttranslational modification]
1088720008035	H+ Antiporter protein; Region: 2A0121; TIGR00900
1088720008036	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1088720008037	non-specific DNA binding site [nucleotide binding]; other site
1088720008038	salt bridge; other site
1088720008039	sequence-specific DNA binding site [nucleotide binding]; other site
1088720008040	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
1088720008041	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1088720008042	non-specific DNA binding site [nucleotide binding]; other site
1088720008043	salt bridge; other site
1088720008044	sequence-specific DNA binding site [nucleotide binding]; other site
1088720008045	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
1088720008046	BacA is a bacterial lysin from Enterococcus faecalis that degrades bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues. BacA is homologous to the YbfG and YkuG lysins of...; Region: GH25_BacA-like; cd06418
1088720008047	active site
1088720008048	F420-dependent oxidoreductase, CPS_4043 family; Region: F420_CPS_4043; TIGR03842
1088720008049	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1088720008050	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1088720008051	substrate binding pocket [chemical binding]; other site
1088720008052	membrane-bound complex binding site; other site
1088720008053	hinge residues; other site
1088720008054	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1088720008055	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1088720008056	dimer interface [polypeptide binding]; other site
1088720008057	conserved gate region; other site
1088720008058	putative PBP binding loops; other site
1088720008059	ABC-ATPase subunit interface; other site
1088720008060	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1088720008061	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1088720008062	Walker A/P-loop; other site
1088720008063	ATP binding site [chemical binding]; other site
1088720008064	Q-loop/lid; other site
1088720008065	ABC transporter signature motif; other site
1088720008066	Walker B; other site
1088720008067	D-loop; other site
1088720008068	H-loop/switch region; other site
1088720008069	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1088720008070	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1088720008071	Protein of unknown function (DUF975); Region: DUF975; cl10504
1088720008072	Uncharacterized conserved protein [Function unknown]; Region: COG3402
1088720008073	Predicted membrane protein [Function unknown]; Region: COG3428
1088720008074	Bacterial PH domain; Region: DUF304; pfam03703
1088720008075	Bacterial PH domain; Region: DUF304; pfam03703
1088720008076	Predicted ATPase [General function prediction only]; Region: COG3910
1088720008077	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
1088720008078	Walker A/P-loop; other site
1088720008079	ATP binding site [chemical binding]; other site
1088720008080	Q-loop/lid; other site
1088720008081	ABC transporter signature motif; other site
1088720008082	Walker B; other site
1088720008083	D-loop; other site
1088720008084	H-loop/switch region; other site
1088720008085	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3001
1088720008086	Phosphotransferase enzyme family; Region: APH; pfam01636
1088720008087	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1088720008088	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1088720008089	Walker A/P-loop; other site
1088720008090	ATP binding site [chemical binding]; other site
1088720008091	Q-loop/lid; other site
1088720008092	ABC transporter signature motif; other site
1088720008093	Walker B; other site
1088720008094	D-loop; other site
1088720008095	H-loop/switch region; other site
1088720008096	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1088720008097	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1088720008098	substrate binding pocket [chemical binding]; other site
1088720008099	membrane-bound complex binding site; other site
1088720008100	hinge residues; other site
1088720008101	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1088720008102	dimer interface [polypeptide binding]; other site
1088720008103	conserved gate region; other site
1088720008104	putative PBP binding loops; other site
1088720008105	ABC-ATPase subunit interface; other site
1088720008106	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1088720008107	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1088720008108	substrate binding pocket [chemical binding]; other site
1088720008109	membrane-bound complex binding site; other site
1088720008110	hinge residues; other site
1088720008111	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1088720008112	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1088720008113	dimer interface [polypeptide binding]; other site
1088720008114	conserved gate region; other site
1088720008115	putative PBP binding loops; other site
1088720008116	ABC-ATPase subunit interface; other site
1088720008117	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1088720008118	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1088720008119	Integral membrane protein DUF95; Region: DUF95; pfam01944
1088720008120	MoxR-like ATPases [General function prediction only]; Region: COG0714
1088720008121	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1088720008122	Walker A motif; other site
1088720008123	ATP binding site [chemical binding]; other site
1088720008124	Walker B motif; other site
1088720008125	arginine finger; other site
1088720008126	Protein of unknown function DUF58; Region: DUF58; pfam01882
1088720008127	This family is most closely related to the GT1 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be...; Region: GT1_amsD_like; cd03820
1088720008128	putative ADP-binding pocket [chemical binding]; other site
1088720008129	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1088720008130	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
1088720008131	Aspartase; Region: Aspartase; cd01357
1088720008132	active sites [active]
1088720008133	tetramer interface [polypeptide binding]; other site
1088720008134	Malic enzyme [Energy production and conversion]; Region: SfcA; COG0281
1088720008135	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1088720008136	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
1088720008137	putative NAD(P) binding site [chemical binding]; other site
1088720008138	2-hydroxycarboxylate transporter family; Region: 2HCT; pfam03390
1088720008139	PAS domain S-box; Region: sensory_box; TIGR00229
1088720008140	PAS domain; Region: PAS; smart00091
1088720008141	putative active site [active]
1088720008142	heme pocket [chemical binding]; other site
1088720008143	Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms]; Region: CitB; COG4565
1088720008144	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1088720008145	active site
1088720008146	phosphorylation site [posttranslational modification]
1088720008147	intermolecular recognition site; other site
1088720008148	dimerization interface [polypeptide binding]; other site
1088720008149	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
1088720008150	Herpesviridae UL52/UL70 DNA primase; Region: Herpes_UL52; cl17300
1088720008151	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
1088720008152	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_4; cd12162
1088720008153	putative ligand binding site [chemical binding]; other site
1088720008154	putative NAD binding site [chemical binding]; other site
1088720008155	catalytic site [active]
1088720008156	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1088720008157	NAD binding domain of 6-phosphogluconate dehydrogenase; Region: NAD_binding_2; pfam03446
1088720008158	GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518
1088720008159	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
1088720008160	catalytic triad [active]
1088720008161	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
1088720008162	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1088720008163	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1088720008164	active site
1088720008165	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1088720008166	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
1088720008167	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1088720008168	Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657
1088720008169	substrate binding pocket [chemical binding]; other site
1088720008170	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1088720008171	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
1088720008172	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1088720008173	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1088720008174	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1088720008175	active site
1088720008176	phosphorylation site [posttranslational modification]
1088720008177	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1088720008178	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1088720008179	DNA-binding interface [nucleotide binding]; DNA binding site
1088720008180	PRD domain; Region: PRD; pfam00874
1088720008181	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1088720008182	active site
1088720008183	P-loop; other site
1088720008184	phosphorylation site [posttranslational modification]
1088720008185	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cl00163
1088720008186	active site
1088720008187	phosphorylation site [posttranslational modification]
1088720008188	Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism]; Region: MtlA; COG2213
1088720008189	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
1088720008190	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
1088720008191	active site
1088720008192	P-loop; other site
1088720008193	phosphorylation site [posttranslational modification]
1088720008194	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
1088720008195	active site
1088720008196	P-loop; other site
1088720008197	phosphorylation site [posttranslational modification]
1088720008198	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1088720008199	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1088720008200	active site
1088720008201	trimer interface [polypeptide binding]; other site
1088720008202	allosteric site; other site
1088720008203	active site lid [active]
1088720008204	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1088720008205	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1088720008206	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1088720008207	active site
1088720008208	motif I; other site
1088720008209	motif II; other site
1088720008210	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1088720008211	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1088720008212	non-specific DNA binding site [nucleotide binding]; other site
1088720008213	salt bridge; other site
1088720008214	sequence-specific DNA binding site [nucleotide binding]; other site
1088720008215	Predicted Zn peptidase [Amino acid transport and metabolism]; Region: COG2856
1088720008216	HlyD family secretion protein; Region: HlyD_2; pfam12700
1088720008217	HlyD family secretion protein; Region: HlyD_3; pfam13437
1088720008218	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1088720008219	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1088720008220	Walker A/P-loop; other site
1088720008221	ATP binding site [chemical binding]; other site
1088720008222	Q-loop/lid; other site
1088720008223	ABC transporter signature motif; other site
1088720008224	Walker B; other site
1088720008225	D-loop; other site
1088720008226	H-loop/switch region; other site
1088720008227	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1088720008228	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1088720008229	FtsX-like permease family; Region: FtsX; pfam02687
1088720008230	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
1088720008231	alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases; Region: MDR_like_2; cd05289
1088720008232	putative NAD(P) binding site [chemical binding]; other site
1088720008233	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1088720008234	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1088720008235	non-specific DNA binding site [nucleotide binding]; other site
1088720008236	salt bridge; other site
1088720008237	sequence-specific DNA binding site [nucleotide binding]; other site
1088720008238	Polyketide cyclase / dehydrase and lipid transport; Region: Polyketide_cyc2; pfam10604
1088720008239	hydrophobic ligand binding site; other site
1088720008240	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
1088720008241	KxYKxGKxW signal peptide; Region: KxYKxGKxW; TIGR03715
1088720008242	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
1088720008243	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
1088720008244	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
1088720008245	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
1088720008246	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
1088720008247	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
1088720008248	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
1088720008249	transaminase; Reviewed; Region: PRK08068
1088720008250	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1088720008251	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1088720008252	homodimer interface [polypeptide binding]; other site
1088720008253	catalytic residue [active]
1088720008254	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1088720008255	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_5; cd07583
1088720008256	putative active site [active]
1088720008257	catalytic triad [active]
1088720008258	putative dimer interface [polypeptide binding]; other site
1088720008259	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1088720008260	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1088720008261	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
1088720008262	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1088720008263	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
1088720008264	putative active site [active]
1088720008265	metal binding site [ion binding]; metal-binding site
1088720008266	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1088720008267	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
1088720008268	metal binding site [ion binding]; metal-binding site
1088720008269	dimer interface [polypeptide binding]; other site
1088720008270	Protein of unknown function (DUF3815); Region: DUF3815; pfam12821
1088720008271	Uncharacterized conserved protein [Function unknown]; Region: COG2966
1088720008272	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
1088720008273	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
1088720008274	tRNA:m(5)U-54 methyltransferase; Region: gid_trmFO; TIGR00137
1088720008275	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1088720008276	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
1088720008277	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1088720008278	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1088720008279	G1 box; other site
1088720008280	GTP/Mg2+ binding site [chemical binding]; other site
1088720008281	Switch I region; other site
1088720008282	G2 box; other site
1088720008283	Switch II region; other site
1088720008284	G3 box; other site
1088720008285	G4 box; other site
1088720008286	G5 box; other site
1088720008287	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
1088720008288	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
1088720008289	jag_K homology RNA-binding domain. The KH domain is found in proteins homologous to the Bacillus subtilis protein Jag, which is associated with SpoIIIJ and is necessary for the third stage of sporulation.  The KH motif is a beta-alpha-alpha-beta-beta...; Region: jag_KH; cd02414
1088720008290	G-X-X-G motif; other site
1088720008291	R3H domain found in proteins homologous to Bacillus subtilus Jag, which is associated with SpoIIIJ. SpoIIIJ is necessary for the third stage of sporulation. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine...; Region: R3H_jag; cd02644
1088720008292	RxxxH motif; other site
1088720008293	Preprotein translocase subunit YidC [Intracellular trafficking and secretion]; Region: YidC; COG0706
1088720008294	60Kd inner membrane protein; Region: 60KD_IMP; cl00489
1088720008295	ribonuclease P; Reviewed; Region: rnpA; PRK00499
1088720008296	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399