-- dump date   	20140619_124747
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
568704000001	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
568704000002	DnaA N-terminal domain; Region: DnaA_N; pfam11638
568704000003	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568704000004	Walker A motif; other site
568704000005	ATP binding site [chemical binding]; other site
568704000006	Walker B motif; other site
568704000007	arginine finger; other site
568704000008	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
568704000009	DnaA box-binding interface [nucleotide binding]; other site
568704000010	DNA polymerase III subunit beta; Validated; Region: PRK05643
568704000011	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
568704000012	putative DNA binding surface [nucleotide binding]; other site
568704000013	dimer interface [polypeptide binding]; other site
568704000014	beta-clamp/clamp loader binding surface; other site
568704000015	beta-clamp/translesion DNA polymerase binding surface; other site
568704000016	S4-like RNA binding protein [Replication, recombination, and repair]; Region: COG2501
568704000017	recombination protein F; Reviewed; Region: recF; PRK00064
568704000018	ATP-binding cassette domain of RecF; Region: ABC_RecF; cd03242
568704000019	Walker A/P-loop; other site
568704000020	ATP binding site [chemical binding]; other site
568704000021	Q-loop/lid; other site
568704000022	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704000023	ABC transporter signature motif; other site
568704000024	Walker B; other site
568704000025	D-loop; other site
568704000026	H-loop/switch region; other site
568704000027	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
568704000028	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568704000029	Mg2+ binding site [ion binding]; other site
568704000030	G-X-G motif; other site
568704000031	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
568704000032	anchoring element; other site
568704000033	dimer interface [polypeptide binding]; other site
568704000034	ATP binding site [chemical binding]; other site
568704000035	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
568704000036	active site
568704000037	metal binding site [ion binding]; metal-binding site
568704000038	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
568704000039	DNA gyrase subunit A; Validated; Region: PRK05560
568704000040	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
568704000041	CAP-like domain; other site
568704000042	active site
568704000043	primary dimer interface [polypeptide binding]; other site
568704000044	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
568704000045	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
568704000046	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
568704000047	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
568704000048	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
568704000049	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
568704000050	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
568704000051	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
568704000052	catalytic residues [active]
568704000053	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
568704000054	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
568704000055	dimer interface [polypeptide binding]; other site
568704000056	ssDNA binding site [nucleotide binding]; other site
568704000057	tetramer (dimer of dimers) interface [polypeptide binding]; other site
568704000058	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
568704000059	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
568704000060	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
568704000061	dimer interface [polypeptide binding]; other site
568704000062	ssDNA binding site [nucleotide binding]; other site
568704000063	tetramer (dimer of dimers) interface [polypeptide binding]; other site
568704000064	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
568704000065	intracellular protease, PfpI family; Region: PfpI; TIGR01382
568704000066	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
568704000067	proposed catalytic triad [active]
568704000068	conserved cys residue [active]
568704000069	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
568704000070	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
568704000071	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
568704000072	CAAX protease self-immunity; Region: Abi; pfam02517
568704000073	ABC-2 type transporter; Region: ABC2_membrane; cl17235
568704000074	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
568704000075	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
568704000076	Walker A/P-loop; other site
568704000077	ATP binding site [chemical binding]; other site
568704000078	Q-loop/lid; other site
568704000079	ABC transporter signature motif; other site
568704000080	Walker B; other site
568704000081	D-loop; other site
568704000082	H-loop/switch region; other site
568704000083	Ammonium Transporter Family; Region: Ammonium_transp; cl03012
568704000084	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_3; pfam13738
568704000085	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883
568704000086	CHAP domain; Region: CHAP; pfam05257
568704000087	Surface antigen [General function prediction only]; Region: COG3942
568704000088	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
568704000089	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
568704000090	FtsX-like permease family; Region: FtsX; pfam02687
568704000091	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
568704000092	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
568704000093	Walker A/P-loop; other site
568704000094	ATP binding site [chemical binding]; other site
568704000095	Q-loop/lid; other site
568704000096	ABC transporter signature motif; other site
568704000097	Walker B; other site
568704000098	D-loop; other site
568704000099	H-loop/switch region; other site
568704000100	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
568704000101	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
568704000102	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
568704000103	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
568704000104	active site
568704000105	motif I; other site
568704000106	motif II; other site
568704000107	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
568704000108	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
568704000109	Protein of unknown function (DUF1211); Region: DUF1211; cl01421
568704000110	galactoside O-acetyltransferase; Reviewed; Region: lacA; PRK09527
568704000111	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
568704000112	active site
568704000113	substrate binding site [chemical binding]; other site
568704000114	trimer interface [polypeptide binding]; other site
568704000115	CoA binding site [chemical binding]; other site
568704000116	Peptidase family C69; Region: Peptidase_C69; pfam03577
568704000117	Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane]; Region: COG3409
568704000118	BacA is a bacterial lysin from Enterococcus faecalis that degrades bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues. BacA is homologous to the YbfG and YkuG lysins of...; Region: GH25_BacA-like; cd06418
568704000119	active site
568704000120	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
568704000121	Predicted membrane protein [Function unknown]; Region: COG4392
568704000122	beta-D-glucuronidase; Provisional; Region: PRK10150
568704000123	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
568704000124	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
568704000125	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
568704000126	Glycosyl hydrolase family 59; Region: Glyco_hydro_59; pfam02057
568704000127	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
568704000128	2-keto-3-deoxy-6-phosphogluconate aldolase [Carbohydrate transport and metabolism]; Region: Eda; COG0800
568704000129	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
568704000130	active site
568704000131	intersubunit interface [polypeptide binding]; other site
568704000132	catalytic residue [active]
568704000133	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
568704000134	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
568704000135	substrate binding site [chemical binding]; other site
568704000136	ATP binding site [chemical binding]; other site
568704000137	Glucuronate isomerase; Region: UxaC; pfam02614
568704000138	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
568704000139	mannonate dehydratase; Region: uxuA; TIGR00695
568704000140	mannonate dehydratase; Provisional; Region: PRK03906
568704000141	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
568704000142	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
568704000143	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
568704000144	O-Glycosyl hydrolase family 30; Region: Glyco_hydro_30; pfam02055
568704000145	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704000146	putative substrate translocation pore; other site
568704000147	Major Facilitator Superfamily; Region: MFS_1; pfam07690
568704000148	Transcriptional regulators [Transcription]; Region: GntR; COG1802
568704000149	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568704000150	DNA-binding site [nucleotide binding]; DNA binding site
568704000151	FCD domain; Region: FCD; pfam07729
568704000152	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
568704000153	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
568704000154	substrate binding site [chemical binding]; other site
568704000155	ATP binding site [chemical binding]; other site
568704000156	Glycosyl hydrolase family 59; Region: Glyco_hydro_59; pfam02057
568704000157	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
568704000158	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704000159	Major Facilitator Superfamily; Region: MFS_1; pfam07690
568704000160	putative substrate translocation pore; other site
568704000161	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704000162	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
568704000163	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
568704000164	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
568704000165	MMPL family; Region: MMPL; pfam03176
568704000166	X-X-X-Leu-X-X-Gly heptad repeats; Region: xxxLxxG_by_4; TIGR03057
568704000167	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
568704000168	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
568704000169	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
568704000170	N-ethylammeline chlorohydrolase; Provisional; Region: PRK07228
568704000171	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
568704000172	active site
568704000173	putative diguanylate cyclase; Provisional; Region: PRK09776
568704000174	Protein of unknown function (DUF3100); Region: DUF3100; pfam11299
568704000175	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568704000176	dimer interface [polypeptide binding]; other site
568704000177	conserved gate region; other site
568704000178	putative PBP binding loops; other site
568704000179	ABC-ATPase subunit interface; other site
568704000180	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
568704000181	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568704000182	dimer interface [polypeptide binding]; other site
568704000183	conserved gate region; other site
568704000184	putative PBP binding loops; other site
568704000185	ABC-ATPase subunit interface; other site
568704000186	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
568704000187	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
568704000188	Walker A/P-loop; other site
568704000189	ATP binding site [chemical binding]; other site
568704000190	Q-loop/lid; other site
568704000191	ABC transporter signature motif; other site
568704000192	Walker B; other site
568704000193	D-loop; other site
568704000194	H-loop/switch region; other site
568704000195	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
568704000196	heavy metal translocating P-type ATPase; Region: ATPase-IB_hvy; TIGR01525
568704000197	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
568704000198	Soluble P-type ATPase [General function prediction only]; Region: COG4087
568704000199	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
568704000200	metal-binding site [ion binding]
568704000201	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cl00264
568704000202	dinuclear metal binding motif [ion binding]; other site
568704000203	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
568704000204	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
568704000205	ligand binding site [chemical binding]; other site
568704000206	flexible hinge region; other site
568704000207	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
568704000208	putative switch regulator; other site
568704000209	non-specific DNA interactions [nucleotide binding]; other site
568704000210	DNA binding site [nucleotide binding]
568704000211	sequence specific DNA binding site [nucleotide binding]; other site
568704000212	putative cAMP binding site [chemical binding]; other site
568704000213	CAAX protease self-immunity; Region: Abi; pfam02517
568704000214	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
568704000215	active site
568704000216	P-loop; other site
568704000217	phosphorylation site [posttranslational modification]
568704000218	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
568704000219	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
568704000220	active site
568704000221	phosphorylation site [posttranslational modification]
568704000222	alpha-mannosidase; Provisional; Region: PRK09819
568704000223	N-terminal catalytic domain of Escherichia coli alpha-mannosidase MngB and its bacterial homologs; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_EcMngB_like; cd10815
568704000224	active site
568704000225	metal binding site [ion binding]; metal-binding site
568704000226	catalytic site [active]
568704000227	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; cl08536
568704000228	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
568704000229	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
568704000230	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
568704000231	putative active site [active]
568704000232	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
568704000233	beta-galactosidase; Region: BGL; TIGR03356
568704000234	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
568704000235	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
568704000236	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
568704000237	nucleotide binding site [chemical binding]; other site
568704000238	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
568704000239	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
568704000240	substrate binding site [chemical binding]; other site
568704000241	active site
568704000242	catalytic residues [active]
568704000243	heterodimer interface [polypeptide binding]; other site
568704000244	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
568704000245	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
568704000246	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568704000247	catalytic residue [active]
568704000248	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
568704000249	active site
568704000250	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
568704000251	active site
568704000252	ribulose/triose binding site [chemical binding]; other site
568704000253	phosphate binding site [ion binding]; other site
568704000254	substrate (anthranilate) binding pocket [chemical binding]; other site
568704000255	product (indole) binding pocket [chemical binding]; other site
568704000256	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
568704000257	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
568704000258	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
568704000259	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704000260	Major Facilitator Superfamily; Region: MFS_1; pfam07690
568704000261	putative substrate translocation pore; other site
568704000262	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704000263	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
568704000264	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
568704000265	Catalytic domain of glycoside hydrolase (GH) families 38 and 57, lactam utilization protein LamB/YcsF family proteins, YdjC-family proteins, and similar proteins; Region: GH38-57_N_LamB_YdjC_SF; cl17191
568704000266	Class I aldolases; Region: Aldolase_Class_I; cl17187
568704000267	gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Region: galliderm_ABC; TIGR03740
568704000268	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
568704000269	Walker A/P-loop; other site
568704000270	ATP binding site [chemical binding]; other site
568704000271	Q-loop/lid; other site
568704000272	ABC transporter signature motif; other site
568704000273	Walker B; other site
568704000274	D-loop; other site
568704000275	H-loop/switch region; other site
568704000276	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568704000277	non-specific DNA binding site [nucleotide binding]; other site
568704000278	salt bridge; other site
568704000279	sequence-specific DNA binding site [nucleotide binding]; other site
568704000280	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
568704000281	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; cl17405
568704000282	dihydrodipicolinate reductase; Provisional; Region: PRK00048
568704000283	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
568704000284	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
568704000285	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
568704000286	dihydrodipicolinate synthase; Region: dapA; TIGR00674
568704000287	dimer interface [polypeptide binding]; other site
568704000288	active site
568704000289	catalytic residue [active]
568704000290	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
568704000291	M20 Peptidase Aminoacyclase-1 YkuR-like proteins, including YkuR and Ama/HipO/HyuC proteins; Region: M20_Acy1_YkuR_like; cd05670
568704000292	metal binding site [ion binding]; metal-binding site
568704000293	putative dimer interface [polypeptide binding]; other site
568704000294	Tetrahydrodipicolinate succinyltransferase N-terminal; Region: DapH_N; pfam08503
568704000295	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Region: DapD_Ac; TIGR03532
568704000296	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
568704000297	putative trimer interface [polypeptide binding]; other site
568704000298	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
568704000299	putative CoA binding site [chemical binding]; other site
568704000300	putative trimer interface [polypeptide binding]; other site
568704000301	putative CoA binding site [chemical binding]; other site
568704000302	diaminopimelate decarboxylase; Region: lysA; TIGR01048
568704000303	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
568704000304	active site
568704000305	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
568704000306	substrate binding site [chemical binding]; other site
568704000307	catalytic residues [active]
568704000308	dimer interface [polypeptide binding]; other site
568704000309	aspartate kinase; Reviewed; Region: PRK09034
568704000310	AAK_AKiii-YclM-BS: Amino Acid Kinase Superfamily (AAK), AKiii-YclM-BS; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII, a monofunctional class enzyme found in...; Region: AAK_AKiii-YclM-BS; cd04245
568704000311	putative catalytic residues [active]
568704000312	putative nucleotide binding site [chemical binding]; other site
568704000313	putative aspartate binding site [chemical binding]; other site
568704000314	ACT domains located C-terminal to the catalytic domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-YclM-BS_1; cd04911
568704000315	allosteric regulatory residue; other site
568704000316	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
568704000317	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
568704000318	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
568704000319	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
568704000320	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
568704000321	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
568704000322	Peptidase M15; Region: Peptidase_M15_3; cl01194
568704000323	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_8; cd04665
568704000324	nudix motif; other site
568704000325	EamA-like transporter family; Region: EamA; pfam00892
568704000326	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
568704000327	tetracycline repressor protein TetR; Provisional; Region: PRK13756
568704000328	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
568704000329	Tetracyclin repressor, C-terminal all-alpha domain; Region: TetR_C; pfam02909
568704000330	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
568704000331	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
568704000332	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
568704000333	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
568704000334	Walker A/P-loop; other site
568704000335	ATP binding site [chemical binding]; other site
568704000336	Q-loop/lid; other site
568704000337	ABC transporter signature motif; other site
568704000338	Walker B; other site
568704000339	D-loop; other site
568704000340	H-loop/switch region; other site
568704000341	Class III nucleotidyl cyclases; Region: Nucleotidyl_cyc_III; cl11967
568704000342	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
568704000343	DHH family; Region: DHH; pfam01368
568704000344	DHHA1 domain; Region: DHHA1; pfam02272
568704000345	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
568704000346	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
568704000347	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
568704000348	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
568704000349	replicative DNA helicase; Provisional; Region: PRK05748
568704000350	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
568704000351	Walker A motif; other site
568704000352	ATP binding site [chemical binding]; other site
568704000353	Walker B motif; other site
568704000354	DNA binding loops [nucleotide binding]
568704000355	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
568704000356	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
568704000357	active site turn [active]
568704000358	phosphorylation site [posttranslational modification]
568704000359	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
568704000360	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
568704000361	HPr interaction site; other site
568704000362	glycerol kinase (GK) interaction site [polypeptide binding]; other site
568704000363	active site
568704000364	phosphorylation site [posttranslational modification]
568704000365	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
568704000366	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
568704000367	putative active site [active]
568704000368	Uncharacterized conserved protein [Function unknown]; Region: COG3589
568704000369	Bacterial protein of unknown function (DUF871); Region: DUF871; pfam05913
568704000370	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
568704000371	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
568704000372	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
568704000373	putative active site [active]
568704000374	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
568704000375	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
568704000376	Transcriptional regulator C-terminal region; Region: TetR_C_8; pfam14278
568704000377	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
568704000378	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
568704000379	Walker A/P-loop; other site
568704000380	ATP binding site [chemical binding]; other site
568704000381	Q-loop/lid; other site
568704000382	ABC transporter signature motif; other site
568704000383	Walker B; other site
568704000384	D-loop; other site
568704000385	H-loop/switch region; other site
568704000386	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
568704000387	FtsX-like permease family; Region: FtsX; pfam02687
568704000388	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
568704000389	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
568704000390	FtsX-like permease family; Region: FtsX; pfam02687
568704000391	Amidohydrolase; Region: Amidohydro_2; pfam04909
568704000392	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
568704000393	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
568704000394	GDP-binding site [chemical binding]; other site
568704000395	ACT binding site; other site
568704000396	IMP binding site; other site
568704000397	heavy metal translocating P-type ATPase; Region: ATPase-IB_hvy; TIGR01525
568704000398	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
568704000399	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
568704000400	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
568704000401	dimerization interface [polypeptide binding]; other site
568704000402	putative DNA binding site [nucleotide binding]; other site
568704000403	putative Zn2+ binding site [ion binding]; other site
568704000404	Major Facilitator Superfamily; Region: MFS_1; pfam07690
568704000405	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
568704000406	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568704000407	non-specific DNA binding site [nucleotide binding]; other site
568704000408	salt bridge; other site
568704000409	sequence-specific DNA binding site [nucleotide binding]; other site
568704000410	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
568704000411	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704000412	Walker A/P-loop; other site
568704000413	ATP binding site [chemical binding]; other site
568704000414	Q-loop/lid; other site
568704000415	ABC transporter signature motif; other site
568704000416	Walker B; other site
568704000417	D-loop; other site
568704000418	H-loop/switch region; other site
568704000419	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
568704000420	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
568704000421	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
568704000422	ATP cone domain; Region: ATP-cone; pfam03477
568704000423	Class III ribonucleotide reductase; Region: RNR_III; cd01675
568704000424	effector binding site; other site
568704000425	active site
568704000426	Zn binding site [ion binding]; other site
568704000427	glycine loop; other site
568704000428	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
568704000429	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568704000430	non-specific DNA binding site [nucleotide binding]; other site
568704000431	salt bridge; other site
568704000432	sequence-specific DNA binding site [nucleotide binding]; other site
568704000433	PAP2_like_6 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which mainly contains bacterial proteins, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_6; cd03396
568704000434	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
568704000435	active site
568704000436	Microcin C7 self-immunity protein determines resistance to exogenous microcin C7; Region: Peptidase_S66_mccF_like; cd07062
568704000437	putative dimer interface [polypeptide binding]; other site
568704000438	catalytic triad [active]
568704000439	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
568704000440	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
568704000441	ATP-grasp domain; Region: ATP-grasp_4; cl17255
568704000442	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
568704000443	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704000444	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
568704000445	HAMP domain; Region: HAMP; pfam00672
568704000446	dimerization interface [polypeptide binding]; other site
568704000447	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
568704000448	dimer interface [polypeptide binding]; other site
568704000449	phosphorylation site [posttranslational modification]
568704000450	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568704000451	ATP binding site [chemical binding]; other site
568704000452	Mg2+ binding site [ion binding]; other site
568704000453	G-X-G motif; other site
568704000454	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
568704000455	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568704000456	active site
568704000457	phosphorylation site [posttranslational modification]
568704000458	intermolecular recognition site; other site
568704000459	dimerization interface [polypeptide binding]; other site
568704000460	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
568704000461	DNA binding site [nucleotide binding]
568704000462	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
568704000463	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
568704000464	DNA binding site [nucleotide binding]
568704000465	active site
568704000466	D-Lactate dehydrogenase and D-2-Hydroxyisocaproic acid dehydrogenase (D-HicDH), NAD-binding and catalytic domains; Region: LDH; cd12186
568704000467	D-lactate dehydrogenase; Validated; Region: PRK08605
568704000468	homodimer interface [polypeptide binding]; other site
568704000469	ligand binding site [chemical binding]; other site
568704000470	NAD binding site [chemical binding]; other site
568704000471	catalytic site [active]
568704000472	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
568704000473	active site
568704000474	P-loop; other site
568704000475	phosphorylation site [posttranslational modification]
568704000476	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
568704000477	active site
568704000478	methionine cluster; other site
568704000479	phosphorylation site [posttranslational modification]
568704000480	metal binding site [ion binding]; metal-binding site
568704000481	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
568704000482	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
568704000483	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
568704000484	beta-galactosidase; Region: BGL; TIGR03356
568704000485	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568704000486	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
568704000487	DNA-binding site [nucleotide binding]; DNA binding site
568704000488	UTRA domain; Region: UTRA; pfam07702
568704000489	Protein of unknown function (DUF1304); Region: DUF1304; pfam06993
568704000490	Protein of unknown function (DUF1516); Region: DUF1516; pfam07457
568704000491	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
568704000492	DsrE/DsrF-like family; Region: DrsE; cl00672
568704000493	N-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_N_like; cd08346
568704000494	Zn binding site [ion binding]; other site
568704000495	C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_C_like; cd08347
568704000496	Zn binding site [ion binding]; other site
568704000497	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
568704000498	WxL domain surface cell wall-binding; Region: WxL; pfam13731
568704000499	Bacterial protein of unknown function (DUF916); Region: DUF916; pfam06030
568704000500	Protein of unknown function C-terminal (DUF3324); Region: DUF3324; pfam11797
568704000501	Mga helix-turn-helix domain; Region: Mga; pfam05043
568704000502	Protein of unknown function (DUF805); Region: DUF805; pfam05656
568704000503	Protein of unknown function (DUF805); Region: DUF805; pfam05656
568704000504	recombination factor protein RarA; Reviewed; Region: PRK13342
568704000505	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568704000506	Walker A motif; other site
568704000507	ATP binding site [chemical binding]; other site
568704000508	Walker B motif; other site
568704000509	arginine finger; other site
568704000510	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
568704000511	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
568704000512	propionate/acetate kinase; Provisional; Region: PRK12379
568704000513	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
568704000514	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
568704000515	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
568704000516	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
568704000517	FGGY family of carbohydrate kinases; Region: FGGY; cd00366
568704000518	N- and C-terminal domain interface [polypeptide binding]; other site
568704000519	active site
568704000520	MgATP binding site [chemical binding]; other site
568704000521	catalytic site [active]
568704000522	metal binding site [ion binding]; metal-binding site
568704000523	carbohydrate binding site [chemical binding]; other site
568704000524	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
568704000525	intersubunit interface [polypeptide binding]; other site
568704000526	active site
568704000527	zinc binding site [ion binding]; other site
568704000528	Na+ binding site [ion binding]; other site
568704000529	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK09410
568704000530	phosphoprotein phosphatases of the metallophosphatase superfamily, metallophosphatase domain; Region: MPP_PPP_family; cd00144
568704000531	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
568704000532	active site
568704000533	metal binding site [ion binding]; metal-binding site
568704000534	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
568704000535	endonuclease III; Region: ENDO3c; smart00478
568704000536	minor groove reading motif; other site
568704000537	helix-hairpin-helix signature motif; other site
568704000538	substrate binding pocket [chemical binding]; other site
568704000539	active site
568704000540	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704000541	Major Facilitator Superfamily; Region: MFS_1; pfam07690
568704000542	putative substrate translocation pore; other site
568704000543	gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Region: galliderm_ABC; TIGR03740
568704000544	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704000545	Walker A/P-loop; other site
568704000546	ATP binding site [chemical binding]; other site
568704000547	Q-loop/lid; other site
568704000548	ABC transporter signature motif; other site
568704000549	Walker B; other site
568704000550	D-loop; other site
568704000551	H-loop/switch region; other site
568704000552	putative phosphoketolase; Provisional; Region: PRK05261
568704000553	Thiamine pyrophosphate (TPP) family, Phosphoketolase (PK) subfamily, TPP-binding module; PK catalyzes the conversion of D-xylulose 5-phosphate and phosphate to acetyl phosphate, D-glyceraldehyde-3-phosphate and H2O. This enzyme requires divalent...; Region: TPP_PK; cd02011
568704000554	TPP-binding site; other site
568704000555	XFP C-terminal domain; Region: XFP_C; pfam09363
568704000556	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
568704000557	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
568704000558	peptide binding site [polypeptide binding]; other site
568704000559	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704000560	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
568704000561	Walker A/P-loop; other site
568704000562	ATP binding site [chemical binding]; other site
568704000563	Q-loop/lid; other site
568704000564	ABC transporter signature motif; other site
568704000565	Walker B; other site
568704000566	D-loop; other site
568704000567	H-loop/switch region; other site
568704000568	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
568704000569	nudix motif; other site
568704000570	FAD-NAD(P)-binding; Region: NAD_binding_9; pfam13454
568704000571	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
568704000572	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
568704000573	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
568704000574	Repair protein; Region: Repair_PSII; pfam04536
568704000575	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
568704000576	Protein of unknown function (DUF1634); Region: DUF1634; pfam07843
568704000577	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
568704000578	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
568704000579	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
568704000580	NAD binding site [chemical binding]; other site
568704000581	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
568704000582	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
568704000583	Transglycosylase associated protein; Region: Transgly_assoc; cl00978
568704000584	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
568704000585	Small integral membrane protein (DUF2273); Region: DUF2273; pfam10031
568704000586	Asp23 family; Region: Asp23; pfam03780
568704000587	Asp23 family; Region: Asp23; pfam03780
568704000588	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG1011
568704000589	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568704000590	motif II; other site
568704000591	Protein of unknown function (DUF969); Region: DUF969; pfam06149
568704000592	Predicted membrane protein [Function unknown]; Region: COG3817
568704000593	Protein of unknown function (DUF979); Region: DUF979; pfam06166
568704000594	Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I:  Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from...; Region: Peptidase_C15; cd00501
568704000595	putative substrate binding pocket [chemical binding]; other site
568704000596	AC domain interface; other site
568704000597	catalytic triad [active]
568704000598	AB domain interface; other site
568704000599	interchain disulfide; other site
568704000600	Predicted dinucleotide-binding enzymes [General function prediction only]; Region: COG2085
568704000601	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; pfam03807
568704000602	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
568704000603	catalytic triad [active]
568704000604	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
568704000605	16S rRNA methyltransferase GidB; Reviewed; Region: gidB; PRK00107
568704000606	nucleoid occlusion protein; Region: nucleoid_noc; TIGR04285
568704000607	ParB-like nuclease domain; Region: ParBc; pfam02195
568704000608	KorB domain; Region: KorB; pfam08535
568704000609	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
568704000610	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
568704000611	P-loop; other site
568704000612	Magnesium ion binding site [ion binding]; other site
568704000613	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
568704000614	Magnesium ion binding site [ion binding]; other site
568704000615	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
568704000616	ParB-like nuclease domain; Region: ParB; smart00470
568704000617	KorB domain; Region: KorB; pfam08535
568704000618	Bacterial protein of unknown function (DUF951); Region: DUF951; pfam06107
568704000619	GTP-binding protein YchF; Reviewed; Region: PRK09601
568704000620	YchF GTPase; Region: YchF; cd01900
568704000621	G1 box; other site
568704000622	GTP/Mg2+ binding site [chemical binding]; other site
568704000623	Switch I region; other site
568704000624	G2 box; other site
568704000625	Switch II region; other site
568704000626	G3 box; other site
568704000627	G4 box; other site
568704000628	G5 box; other site
568704000629	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
568704000630	Protein of unknown function (DUF1129); Region: DUF1129; pfam06570
568704000631	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
568704000632	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
568704000633	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
568704000634	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
568704000635	active site
568704000636	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
568704000637	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568704000638	active site
568704000639	phosphorylation site [posttranslational modification]
568704000640	intermolecular recognition site; other site
568704000641	dimerization interface [polypeptide binding]; other site
568704000642	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
568704000643	DNA binding site [nucleotide binding]
568704000644	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
568704000645	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
568704000646	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
568704000647	dimer interface [polypeptide binding]; other site
568704000648	phosphorylation site [posttranslational modification]
568704000649	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568704000650	ATP binding site [chemical binding]; other site
568704000651	Mg2+ binding site [ion binding]; other site
568704000652	G-X-G motif; other site
568704000653	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
568704000654	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
568704000655	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; cl06814
568704000656	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
568704000657	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
568704000658	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
568704000659	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
568704000660	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
568704000661	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
568704000662	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
568704000663	aspartate racemase; Region: asp_race; TIGR00035
568704000664	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
568704000665	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
568704000666	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
568704000667	active site
568704000668	catalytic tetrad [active]
568704000669	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
568704000670	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
568704000671	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
568704000672	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
568704000673	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704000674	putative substrate translocation pore; other site
568704000675	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704000676	Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2; Region: ALDH_F6_MMSDH; cd07085
568704000677	methylmalonic acid semialdehyde dehydrogenase; Region: MMSDH; TIGR01722
568704000678	tetrameric interface [polypeptide binding]; other site
568704000679	NAD binding site [chemical binding]; other site
568704000680	catalytic residues [active]
568704000681	Uncharacterized enzyme involved in inositol metabolism [Carbohydrate transport and metabolism]; Region: IolB; COG3718
568704000682	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
568704000683	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
568704000684	substrate binding site [chemical binding]; other site
568704000685	ATP binding site [chemical binding]; other site
568704000686	Acetolactate synthase [Amino acid transport and metabolism]; Region: COG3962
568704000687	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
568704000688	PYR/PP interface [polypeptide binding]; other site
568704000689	dimer interface [polypeptide binding]; other site
568704000690	TPP binding site [chemical binding]; other site
568704000691	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
568704000692	Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins similar to Rhizobium leguminosarum bv. viciae IolD. IolD plays an important role in myo-inositol catabolism; Region: TPP_IolD; cd02003
568704000693	TPP-binding site; other site
568704000694	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
568704000695	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
568704000696	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
568704000697	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
568704000698	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
568704000699	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
568704000700	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
568704000701	intersubunit interface [polypeptide binding]; other site
568704000702	active site
568704000703	zinc binding site [ion binding]; other site
568704000704	Na+ binding site [ion binding]; other site
568704000705	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235
568704000706	Predicted sugar epimerase [Carbohydrate transport and metabolism]; Region: COG4130
568704000707	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
568704000708	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
568704000709	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
568704000710	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
568704000711	putative active site [active]
568704000712	Predicted 6-phosphogluconate dehydrogenase [Carbohydrate transport and metabolism]; Region: Gnd; COG1023
568704000713	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
568704000714	gluconate kinase, FGGY type; Region: gntK_FGGY; TIGR01314
568704000715	Gluconate kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_GntK; cd07770
568704000716	N- and C-terminal domain interface [polypeptide binding]; other site
568704000717	active site
568704000718	catalytic site [active]
568704000719	metal binding site [ion binding]; metal-binding site
568704000720	carbohydrate binding site [chemical binding]; other site
568704000721	ATP binding site [chemical binding]; other site
568704000722	fructuronate transporter; Provisional; Region: PRK10034; cl15264
568704000723	Citrate transporter; Region: CitMHS; pfam03600
568704000724	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
568704000725	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
568704000726	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
568704000727	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cl00462
568704000728	putative PBP binding regions; other site
568704000729	ABC-ATPase subunit  interface; other site
568704000730	Calcineurin-like phosphoesterase superfamily domain; Region: Metallophos_2; pfam12850
568704000731	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
568704000732	active site
568704000733	metal binding site [ion binding]; metal-binding site
568704000734	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
568704000735	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
568704000736	oligoendopeptidase F; Region: pepF; TIGR00181
568704000737	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_3; cd09608
568704000738	active site
568704000739	Zn binding site [ion binding]; other site
568704000740	Cell envelope-related transcriptional attenuator domain; Region: LytR_cpsA_psr; cl00581
568704000741	Branched-chain amino acid transport protein; Region: Branch_AA_trans; cl00547
568704000742	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
568704000743	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
568704000744	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
568704000745	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
568704000746	active site
568704000747	Protein of unknown function (DUF975); Region: DUF975; cl10504
568704000748	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
568704000749	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
568704000750	Catalytic site [active]
568704000751	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
568704000752	ADP-ribosylglycohydrolase; Region: ADP_ribosyl_GH; pfam03747
568704000753	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
568704000754	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
568704000755	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
568704000756	ABC transporter; Region: ABC_tran_2; pfam12848
568704000757	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
568704000758	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568704000759	S-adenosylmethionine binding site [chemical binding]; other site
568704000760	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
568704000761	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
568704000762	catalytic residues [active]
568704000763	Uncharacterized conserved protein [Function unknown]; Region: COG2966
568704000764	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
568704000765	Protein of unknown function (DUF3815); Region: DUF3815; pfam12821
568704000766	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
568704000767	Type I periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_ligand_binding_like_12; cd06347
568704000768	putative ligand binding site [chemical binding]; other site
568704000769	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
568704000770	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
568704000771	TM-ABC transporter signature motif; other site
568704000772	ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177
568704000773	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
568704000774	TM-ABC transporter signature motif; other site
568704000775	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
568704000776	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
568704000777	Walker A/P-loop; other site
568704000778	ATP binding site [chemical binding]; other site
568704000779	Q-loop/lid; other site
568704000780	ABC transporter signature motif; other site
568704000781	Walker B; other site
568704000782	D-loop; other site
568704000783	H-loop/switch region; other site
568704000784	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
568704000785	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
568704000786	Walker A/P-loop; other site
568704000787	ATP binding site [chemical binding]; other site
568704000788	Q-loop/lid; other site
568704000789	ABC transporter signature motif; other site
568704000790	Walker B; other site
568704000791	D-loop; other site
568704000792	H-loop/switch region; other site
568704000793	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain superfamily; Region: NTP-PPase; cd11523
568704000794	metal binding site [ion binding]; metal-binding site
568704000795	Alpha/beta hydrolase of unknown function (DUF915); Region: DUF915; pfam06028
568704000796	PGAP1-like protein; Region: PGAP1; pfam07819
568704000797	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
568704000798	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
568704000799	intersubunit interface [polypeptide binding]; other site
568704000800	active site
568704000801	catalytic residue [active]
568704000802	phosphopentomutase; Provisional; Region: PRK05362
568704000803	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
568704000804	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
568704000805	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
568704000806	NlpC/P60 family; Region: NLPC_P60; pfam00877
568704000807	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
568704000808	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
568704000809	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; cl17295
568704000810	PTS_IIB_lactose: subunit IIB of enzyme II (EII) of the lactose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS) found in Firmicutes as well as Actinobacteria. In this system, EII is a lactose-specific permease with two...; Region: PTS_IIB_lactose; cd05565
568704000811	active site
568704000812	P-loop; other site
568704000813	phosphorylation site [posttranslational modification]
568704000814	transcriptional antiterminator BglG; Provisional; Region: PRK09772
568704000815	CAT RNA binding domain; Region: CAT_RBD; pfam03123
568704000816	PRD domain; Region: PRD; pfam00874
568704000817	PRD domain; Region: PRD; pfam00874
568704000818	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
568704000819	methionine cluster; other site
568704000820	active site
568704000821	phosphorylation site [posttranslational modification]
568704000822	metal binding site [ion binding]; metal-binding site
568704000823	6-phospho-beta-galactosidase; Provisional; Region: PRK13511
568704000824	beta-galactosidase; Region: BGL; TIGR03356
568704000825	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
568704000826	DEAD/DEAH box helicase; Region: DEAD; pfam00270
568704000827	DEAD_2; Region: DEAD_2; pfam06733
568704000828	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
568704000829	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
568704000830	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
568704000831	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
568704000832	M protein trans-acting positive regulator (MGA) HTH domain; Region: HTH_Mga; pfam08280
568704000833	HTH domain; Region: HTH_11; cl17392
568704000834	PRD domain; Region: PRD; pfam00874
568704000835	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
568704000836	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
568704000837	active site
568704000838	phosphorylation site [posttranslational modification]
568704000839	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
568704000840	active site
568704000841	phosphorylation site [posttranslational modification]
568704000842	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
568704000843	putative PTS system  transporter subunits IIBC; Provisional; Region: PRK11404
568704000844	active site
568704000845	P-loop; other site
568704000846	phosphorylation site [posttranslational modification]
568704000847	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
568704000848	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
568704000849	mannose-6-phosphate isomerase, class I; Region: manA; TIGR00218
568704000850	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
568704000851	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568704000852	DNA-binding site [nucleotide binding]; DNA binding site
568704000853	UTRA domain; Region: UTRA; pfam07702
568704000854	putative sugar isomerase, AgaS family; Region: agaS_fam; TIGR02815
568704000855	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
568704000856	dimer interface [polypeptide binding]; other site
568704000857	active site
568704000858	AgaS-like protein. AgaS contains a SIS (Sugar ISomerase) domain which is found in many phosphosugar isomerases and phosphosugar binding proteins. AgaS is a putative isomerase in Escherichia coli. It is similar to the glucosamine-6-phosphate synthases; Region: SIS_AgaS_like; cd05010
568704000859	putative active site [active]
568704000860	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
568704000861	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
568704000862	active site
568704000863	dimer interface [polypeptide binding]; other site
568704000864	Glycosyl hydrolases family 35; Region: Glyco_hydro_35; pfam01301
568704000865	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
568704000866	active site
568704000867	phosphorylation site [posttranslational modification]
568704000868	PTS system sorbose-specific iic component; Region: EII-Sor; pfam03609
568704000869	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
568704000870	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
568704000871	active pocket/dimerization site; other site
568704000872	active site
568704000873	phosphorylation site [posttranslational modification]
568704000874	Domain of unknown function (DUF1975); Region: DUF1975; pfam09318
568704000875	This family is most closely related to the GT1 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding.  In...; Region: GT1_gtfA_like; cd04949
568704000876	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
568704000877	Domain of unknown function (DUF1975); Region: DUF1975; pfam09318
568704000878	This family is most closely related to the GT1 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding.  In...; Region: GT1_gtfA_like; cd04949
568704000879	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
568704000880	Rap/ran-GAP; Region: Rap_GAP; pfam02145
568704000881	Uncharacterized protein conserved in bacteria (DUF2325); Region: DUF2325; pfam10087
568704000882	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
568704000883	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
568704000884	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568704000885	homodimer interface [polypeptide binding]; other site
568704000886	catalytic residue [active]
568704000887	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
568704000888	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
568704000889	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
568704000890	active site
568704000891	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
568704000892	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
568704000893	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
568704000894	active site
568704000895	P-loop; other site
568704000896	phosphorylation site [posttranslational modification]
568704000897	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
568704000898	active site
568704000899	methionine cluster; other site
568704000900	phosphorylation site [posttranslational modification]
568704000901	metal binding site [ion binding]; metal-binding site
568704000902	exoaminopeptidase; Provisional; Region: PRK09961
568704000903	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
568704000904	oligomer interface [polypeptide binding]; other site
568704000905	active site
568704000906	metal binding site [ion binding]; metal-binding site
568704000907	HTH domain; Region: HTH_11; pfam08279
568704000908	PRD domain; Region: PRD; pfam00874
568704000909	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
568704000910	active site
568704000911	P-loop; other site
568704000912	phosphorylation site [posttranslational modification]
568704000913	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
568704000914	active site
568704000915	phosphorylation site [posttranslational modification]
568704000916	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
568704000917	peptidase T; Region: peptidase-T; TIGR01882
568704000918	metal binding site [ion binding]; metal-binding site
568704000919	dimer interface [polypeptide binding]; other site
568704000920	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
568704000921	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
568704000922	peptide binding site [polypeptide binding]; other site
568704000923	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
568704000924	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568704000925	Coenzyme A binding pocket [chemical binding]; other site
568704000926	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704000927	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
568704000928	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
568704000929	Walker A/P-loop; other site
568704000930	ATP binding site [chemical binding]; other site
568704000931	Q-loop/lid; other site
568704000932	ABC transporter signature motif; other site
568704000933	Rhomboid family; Region: Rhomboid; cl11446
568704000934	Rhomboid family; Region: Rhomboid; cl11446
568704000935	ABC-type cobalt transport system, permease component; Region: ABC_cobalt; cl01943
568704000936	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
568704000937	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
568704000938	Walker A/P-loop; other site
568704000939	ATP binding site [chemical binding]; other site
568704000940	Q-loop/lid; other site
568704000941	ABC transporter signature motif; other site
568704000942	Walker B; other site
568704000943	D-loop; other site
568704000944	H-loop/switch region; other site
568704000945	ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones]; Region: CcmA; COG4133
568704000946	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
568704000947	Walker A/P-loop; other site
568704000948	ATP binding site [chemical binding]; other site
568704000949	Q-loop/lid; other site
568704000950	ABC transporter signature motif; other site
568704000951	Walker B; other site
568704000952	D-loop; other site
568704000953	H-loop/switch region; other site
568704000954	Putative transcription activator [Transcription]; Region: TenA; COG0819
568704000955	Thiamine-precursor transporter protein (ThiW); Region: ThiW; pfam09512
568704000956	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
568704000957	substrate binding site [chemical binding]; other site
568704000958	multimerization interface [polypeptide binding]; other site
568704000959	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
568704000960	ATP binding site [chemical binding]; other site
568704000961	substrate binding site [chemical binding]; other site
568704000962	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
568704000963	thiamine phosphate binding site [chemical binding]; other site
568704000964	active site
568704000965	pyrophosphate binding site [ion binding]; other site
568704000966	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
568704000967	dimer interface [polypeptide binding]; other site
568704000968	substrate binding site [chemical binding]; other site
568704000969	ATP binding site [chemical binding]; other site
568704000970	Amino acid permease; Region: AA_permease_2; pfam13520
568704000971	Transcriptional regulators [Transcription]; Region: PurR; COG1609
568704000972	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
568704000973	DNA binding site [nucleotide binding]
568704000974	domain linker motif; other site
568704000975	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
568704000976	ligand binding site [chemical binding]; other site
568704000977	dimerization interface [polypeptide binding]; other site
568704000978	D-ribose pyranase; Provisional; Region: PRK11797
568704000979	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
568704000980	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
568704000981	Walker A/P-loop; other site
568704000982	ATP binding site [chemical binding]; other site
568704000983	Q-loop/lid; other site
568704000984	ABC transporter signature motif; other site
568704000985	Walker B; other site
568704000986	D-loop; other site
568704000987	H-loop/switch region; other site
568704000988	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
568704000989	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
568704000990	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
568704000991	TM-ABC transporter signature motif; other site
568704000992	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
568704000993	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
568704000994	ligand binding site [chemical binding]; other site
568704000995	dimerization interface [polypeptide binding]; other site
568704000996	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
568704000997	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
568704000998	substrate binding site [chemical binding]; other site
568704000999	dimer interface [polypeptide binding]; other site
568704001000	ATP binding site [chemical binding]; other site
568704001001	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568704001002	salt bridge; other site
568704001003	non-specific DNA binding site [nucleotide binding]; other site
568704001004	sequence-specific DNA binding site [nucleotide binding]; other site
568704001005	Rhomboid family; Region: Rhomboid; cl11446
568704001006	Protein of unknown function (DUF2785); Region: DUF2785; pfam10978
568704001007	NTF2-like N-terminal transpeptidase domain; Region: MecA_N; pfam05223
568704001008	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
568704001009	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
568704001010	gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Region: galliderm_ABC; TIGR03740
568704001011	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704001012	Walker A/P-loop; other site
568704001013	ATP binding site [chemical binding]; other site
568704001014	Q-loop/lid; other site
568704001015	ABC transporter signature motif; other site
568704001016	Walker B; other site
568704001017	D-loop; other site
568704001018	H-loop/switch region; other site
568704001019	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704001020	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704001021	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
568704001022	MarR family; Region: MarR_2; pfam12802
568704001023	MarR family; Region: MarR_2; cl17246
568704001024	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
568704001025	PRD domain; Region: PRD; pfam00874
568704001026	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
568704001027	active site
568704001028	P-loop; other site
568704001029	phosphorylation site [posttranslational modification]
568704001030	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
568704001031	active site
568704001032	phosphorylation site [posttranslational modification]
568704001033	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
568704001034	active site
568704001035	P-loop; other site
568704001036	phosphorylation site [posttranslational modification]
568704001037	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: PRK12997
568704001038	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
568704001039	intersubunit interface [polypeptide binding]; other site
568704001040	active site
568704001041	zinc binding site [ion binding]; other site
568704001042	Na+ binding site [ion binding]; other site
568704001043	AAA domain; Region: AAA_18; pfam13238
568704001044	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
568704001045	Walker A motif; other site
568704001046	ATP binding site [chemical binding]; other site
568704001047	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
568704001048	active site
568704001049	tetramer interface [polypeptide binding]; other site
568704001050	C4-dicarboxylate transporter [Energy production and conversion]; Region: DcuC; COG3069
568704001051	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
568704001052	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
568704001053	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
568704001054	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568704001055	DNA-binding site [nucleotide binding]; DNA binding site
568704001056	DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes [Carbohydrate transport and metabolism]; Region: FbaB; COG1830
568704001057	Class I aldolases; Region: Aldolase_Class_I; cl17187
568704001058	catalytic residue [active]
568704001059	Glycerol-3-phosphate responsive antiterminator; Region: G3P_antiterm; cl00852
568704001060	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
568704001061	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
568704001062	putative N- and C-terminal domain interface [polypeptide binding]; other site
568704001063	putative active site [active]
568704001064	MgATP binding site [chemical binding]; other site
568704001065	catalytic site [active]
568704001066	metal binding site [ion binding]; metal-binding site
568704001067	putative xylulose binding site [chemical binding]; other site
568704001068	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
568704001069	classical (c) SDRs; Region: SDR_c; cd05233
568704001070	NAD(P) binding site [chemical binding]; other site
568704001071	active site
568704001072	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_10; cd12171
568704001073	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
568704001074	putative ligand binding site [chemical binding]; other site
568704001075	putative NAD binding site [chemical binding]; other site
568704001076	catalytic site [active]
568704001077	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
568704001078	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
568704001079	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
568704001080	HTH domain; Region: HTH_11; cl17392
568704001081	PRD domain; Region: PRD; pfam00874
568704001082	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cl00163
568704001083	active site
568704001084	phosphorylation site [posttranslational modification]
568704001085	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
568704001086	intersubunit interface [polypeptide binding]; other site
568704001087	active site
568704001088	zinc binding site [ion binding]; other site
568704001089	Na+ binding site [ion binding]; other site
568704001090	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
568704001091	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
568704001092	active site
568704001093	phosphorylation site [posttranslational modification]
568704001094	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
568704001095	active site
568704001096	P-loop; other site
568704001097	phosphorylation site [posttranslational modification]
568704001098	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
568704001099	L-sorbose-1-phosphate reductase; Region: sorbose_phosphate_red; cd08238
568704001100	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
568704001101	putative NAD(P) binding site [chemical binding]; other site
568704001102	catalytic Zn binding site [ion binding]; other site
568704001103	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
568704001104	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
568704001105	sorbitol-6-phosphate 2-dehydrogenase; Provisional; Region: PRK06171
568704001106	classical (c) SDRs; Region: SDR_c; cd05233
568704001107	NAD(P) binding site [chemical binding]; other site
568704001108	active site
568704001109	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
568704001110	active pocket/dimerization site; other site
568704001111	active site
568704001112	phosphorylation site [posttranslational modification]
568704001113	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
568704001114	active site
568704001115	phosphorylation site [posttranslational modification]
568704001116	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
568704001117	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; cl01507
568704001118	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
568704001119	intersubunit interface [polypeptide binding]; other site
568704001120	active site
568704001121	zinc binding site [ion binding]; other site
568704001122	Na+ binding site [ion binding]; other site
568704001123	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
568704001124	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
568704001125	transmembrane helices; other site
568704001126	FAD dependent oxidoreductase; Region: FAD_oxidored; pfam12831
568704001127	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
568704001128	Transcriptional regulator [Transcription]; Region: LysR; COG0583
568704001129	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568704001130	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
568704001131	dimerization interface [polypeptide binding]; other site
568704001132	Uncharacterized conserved protein [Function unknown]; Region: COG1912
568704001133	hypothetical protein; Provisional; Region: PRK13661
568704001134	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
568704001135	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
568704001136	Walker A/P-loop; other site
568704001137	ATP binding site [chemical binding]; other site
568704001138	Q-loop/lid; other site
568704001139	ABC transporter signature motif; other site
568704001140	Walker B; other site
568704001141	D-loop; other site
568704001142	H-loop/switch region; other site
568704001143	ATP-binding cassette cobalt transporter; Region: DUF3744; pfam12558
568704001144	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
568704001145	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
568704001146	Walker A/P-loop; other site
568704001147	ATP binding site [chemical binding]; other site
568704001148	Q-loop/lid; other site
568704001149	ABC transporter signature motif; other site
568704001150	Walker B; other site
568704001151	D-loop; other site
568704001152	H-loop/switch region; other site
568704001153	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
568704001154	Transcriptional regulators [Transcription]; Region: PurR; COG1609
568704001155	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
568704001156	DNA binding site [nucleotide binding]
568704001157	domain linker motif; other site
568704001158	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
568704001159	dimerization interface [polypeptide binding]; other site
568704001160	ligand binding site [chemical binding]; other site
568704001161	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704001162	putative substrate translocation pore; other site
568704001163	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
568704001164	Beta-galactosidase C-terminal domain; Region: Glyco_hydro_42C; pfam08533
568704001165	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
568704001166	Ca binding site [ion binding]; other site
568704001167	active site
568704001168	catalytic site [active]
568704001169	fumarate reductase flavoprotein subunit; Validated; Region: PRK06481
568704001170	L-aspartate oxidase; Provisional; Region: PRK06175
568704001171	Predicted oxidoreductase [General function prediction only]; Region: COG3573
568704001172	hypothetical protein; Provisional; Region: PRK06357
568704001173	active site
568704001174	intersubunit interface [polypeptide binding]; other site
568704001175	Zn2+ binding site [ion binding]; other site
568704001176	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
568704001177	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
568704001178	PTS_IIB: subunit IIB of enzyme II (EII) is the central energy-coupling domain of the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In the multienzyme PTS complex, EII is a carbohydrate-specific permease consisting of two cytoplasmic...; Region: PTS_IIB; cl10014
568704001179	active site
568704001180	P-loop; other site
568704001181	phosphorylation site [posttranslational modification]
568704001182	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
568704001183	active site
568704001184	phosphorylation site [posttranslational modification]
568704001185	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
568704001186	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
568704001187	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
568704001188	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
568704001189	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
568704001190	putative substrate binding site [chemical binding]; other site
568704001191	putative ATP binding site [chemical binding]; other site
568704001192	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
568704001193	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
568704001194	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
568704001195	putative active site [active]
568704001196	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
568704001197	active site
568704001198	phosphorylation site [posttranslational modification]
568704001199	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
568704001200	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
568704001201	active site
568704001202	P-loop; other site
568704001203	phosphorylation site [posttranslational modification]
568704001204	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
568704001205	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
568704001206	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568704001207	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
568704001208	active site
568704001209	motif I; other site
568704001210	motif II; other site
568704001211	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568704001212	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
568704001213	Glycoside Hydrolases Family 4; GlvA- and pagL-like glycosidases; Region: GH4_GlvA_pagL_like; cd05298
568704001214	NAD binding site [chemical binding]; other site
568704001215	sugar binding site [chemical binding]; other site
568704001216	divalent metal binding site [ion binding]; other site
568704001217	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
568704001218	dimer interface [polypeptide binding]; other site
568704001219	PTS system, alpha-glucoside-specific IIBC component; Region: PTS-IIBC-alpha; TIGR02005
568704001220	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
568704001221	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
568704001222	active site turn [active]
568704001223	phosphorylation site [posttranslational modification]
568704001224	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
568704001225	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
568704001226	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
568704001227	putative active site [active]
568704001228	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
568704001229	active site turn [active]
568704001230	phosphorylation site [posttranslational modification]
568704001231	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
568704001232	HPr interaction site; other site
568704001233	glycerol kinase (GK) interaction site [polypeptide binding]; other site
568704001234	active site
568704001235	phosphorylation site [posttranslational modification]
568704001236	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
568704001237	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568704001238	motif II; other site
568704001239	HAD-hyrolase-like; Region: Hydrolase_like; pfam13242
568704001240	transcriptional antiterminator BglG; Provisional; Region: PRK09772
568704001241	CAT RNA binding domain; Region: CAT_RBD; pfam03123
568704001242	PRD domain; Region: PRD; pfam00874
568704001243	PRD domain; Region: PRD; pfam00874
568704001244	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
568704001245	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
568704001246	active site turn [active]
568704001247	phosphorylation site [posttranslational modification]
568704001248	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
568704001249	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
568704001250	HPr interaction site; other site
568704001251	glycerol kinase (GK) interaction site [polypeptide binding]; other site
568704001252	active site
568704001253	phosphorylation site [posttranslational modification]
568704001254	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
568704001255	beta-galactosidase; Region: BGL; TIGR03356
568704001256	HTH domain; Region: HTH_11; pfam08279
568704001257	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
568704001258	Mga helix-turn-helix domain; Region: Mga; pfam05043
568704001259	PRD domain; Region: PRD; pfam00874
568704001260	PRD domain; Region: PRD; pfam00874
568704001261	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
568704001262	active site
568704001263	P-loop; other site
568704001264	phosphorylation site [posttranslational modification]
568704001265	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cl00163
568704001266	active site
568704001267	phosphorylation site [posttranslational modification]
568704001268	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
568704001269	intersubunit interface [polypeptide binding]; other site
568704001270	active site
568704001271	zinc binding site [ion binding]; other site
568704001272	Na+ binding site [ion binding]; other site
568704001273	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
568704001274	active site
568704001275	phosphorylation site [posttranslational modification]
568704001276	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
568704001277	active site
568704001278	P-loop; other site
568704001279	phosphorylation site [posttranslational modification]
568704001280	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
568704001281	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
568704001282	Aldose 1-epimerase, similar to Escherichia coli c4013; Region: Aldose_epim_Ec_c4013; cd09023
568704001283	active site
568704001284	catalytic residues [active]
568704001285	Protein of unknown function (DUF1498); Region: DUF1498; cl17840
568704001286	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
568704001287	N- and C-terminal domain interface [polypeptide binding]; other site
568704001288	D-xylulose kinase; Region: XylB; TIGR01312
568704001289	active site
568704001290	MgATP binding site [chemical binding]; other site
568704001291	catalytic site [active]
568704001292	metal binding site [ion binding]; metal-binding site
568704001293	xylulose binding site [chemical binding]; other site
568704001294	homodimer interface [polypeptide binding]; other site
568704001295	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
568704001296	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
568704001297	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
568704001298	active site turn [active]
568704001299	phosphorylation site [posttranslational modification]
568704001300	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
568704001301	putative active site [active]
568704001302	YdjC motif; other site
568704001303	Mg binding site [ion binding]; other site
568704001304	putative homodimer interface [polypeptide binding]; other site
568704001305	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
568704001306	NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195
568704001307	NAD(P) binding site [chemical binding]; other site
568704001308	LDH/MDH dimer interface [polypeptide binding]; other site
568704001309	substrate binding site [chemical binding]; other site
568704001310	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
568704001311	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
568704001312	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
568704001313	putative active site [active]
568704001314	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
568704001315	active site
568704001316	phosphorylation site [posttranslational modification]
568704001317	putative PTS system  transporter subunits IIBC; Provisional; Region: PRK11404
568704001318	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
568704001319	active site
568704001320	P-loop; other site
568704001321	phosphorylation site [posttranslational modification]
568704001322	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
568704001323	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
568704001324	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
568704001325	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568704001326	homodimer interface [polypeptide binding]; other site
568704001327	catalytic residue [active]
568704001328	putative frv operon regulatory protein; Provisional; Region: PRK09863
568704001329	HTH domain; Region: HTH_11; pfam08279
568704001330	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cl00163
568704001331	active site
568704001332	phosphorylation site [posttranslational modification]
568704001333	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
568704001334	putative active site [active]
568704001335	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
568704001336	active site
568704001337	phosphorylation site [posttranslational modification]
568704001338	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
568704001339	active site
568704001340	P-loop; other site
568704001341	phosphorylation site [posttranslational modification]
568704001342	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: PRK12997
568704001343	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
568704001344	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
568704001345	inhibitor site; inhibition site
568704001346	active site
568704001347	dimer interface [polypeptide binding]; other site
568704001348	catalytic residue [active]
568704001349	2-keto-3-deoxy-6-phosphogluconate aldolase [Carbohydrate transport and metabolism]; Region: Eda; COG0800
568704001350	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
568704001351	active site
568704001352	intersubunit interface [polypeptide binding]; other site
568704001353	catalytic residue [active]
568704001354	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
568704001355	Mga helix-turn-helix domain; Region: Mga; pfam05043
568704001356	PRD domain; Region: PRD; pfam00874
568704001357	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
568704001358	active site
568704001359	P-loop; other site
568704001360	phosphorylation site [posttranslational modification]
568704001361	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
568704001362	active site
568704001363	phosphorylation site [posttranslational modification]
568704001364	Predicted transcriptional regulators [Transcription]; Region: COG1733
568704001365	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
568704001366	Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer,  utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cl00514
568704001367	FMN binding site [chemical binding]; other site
568704001368	dimer interface [polypeptide binding]; other site
568704001369	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
568704001370	helix_turn_helix, Lux Regulon; Region: HTH_LUXR; smart00421
568704001371	DNA binding residues [nucleotide binding]
568704001372	dimerization interface [polypeptide binding]; other site
568704001373	YvrJ protein family; Region: YvrJ; pfam12841
568704001374	AtlA is an autolysin found in Gram-positive lactic acid bacteria that degrades bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues. This family includes the AtlA and Aml...; Region: GH25_AtlA-like; cd06522
568704001375	active site
568704001376	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
568704001377	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
568704001378	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
568704001379	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
568704001380	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
568704001381	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
568704001382	FtsX-like permease family; Region: FtsX; pfam02687
568704001383	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
568704001384	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
568704001385	Walker A/P-loop; other site
568704001386	ATP binding site [chemical binding]; other site
568704001387	Q-loop/lid; other site
568704001388	ABC transporter signature motif; other site
568704001389	Walker B; other site
568704001390	D-loop; other site
568704001391	H-loop/switch region; other site
568704001392	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
568704001393	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
568704001394	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
568704001395	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568704001396	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
568704001397	active site
568704001398	motif I; other site
568704001399	motif II; other site
568704001400	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
568704001401	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041; cl17396
568704001402	Transcriptional regulators [Transcription]; Region: PurR; COG1609
568704001403	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
568704001404	DNA binding site [nucleotide binding]
568704001405	domain linker motif; other site
568704001406	Ligand-binding domain of a novel transcription factor implicated in catabolite repression in Bacillus and Clostridium species; Region: PBP1_CcpB_like; cd06286
568704001407	putative dimerization interface [polypeptide binding]; other site
568704001408	putative ligand binding site [chemical binding]; other site
568704001409	PTS system sorbose subfamily IIB component; Region: PTSIIB_sorb; pfam03830
568704001410	active site
568704001411	phosphorylation site [posttranslational modification]
568704001412	PTS system sorbose-specific iic component; Region: EII-Sor; pfam03609
568704001413	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
568704001414	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
568704001415	This family represents an uncharacterized glycosyl hydrolase family 31 (GH31) enzyme found in bacteria and eukaryotes that is related to the XylS xylosidase of Sulfolobus solfataricus. Alpha-xylosidases catalyze the release of an alpha-xylose residue...; Region: GH31_xylosidase_XylS-like; cd06595
568704001416	putative active site [active]
568704001417	putative catalytic site [active]
568704001418	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
568704001419	active pocket/dimerization site; other site
568704001420	active site
568704001421	phosphorylation site [posttranslational modification]
568704001422	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
568704001423	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
568704001424	Ca binding site [ion binding]; other site
568704001425	active site
568704001426	catalytic site [active]
568704001427	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
568704001428	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
568704001429	active site
568704001430	NTP binding site [chemical binding]; other site
568704001431	metal binding triad [ion binding]; metal-binding site
568704001432	Domain of unknown function (DUF4111); Region: DUF4111; pfam13427
568704001433	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
568704001434	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
568704001435	Linear amide C-N hydrolases, choloylglycine hydrolase family; Region: CBAH; pfam02275
568704001436	active site
568704001437	myosin-cross-reactive antigen; Provisional; Region: PRK13977
568704001438	probable dihydroxyacetone kinase regulator; Region: DHAK_reg; TIGR02366
568704001439	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
568704001440	phosphotransferase mannnose-specific family component IIA; Provisional; Region: PRK14484
568704001441	DAK2 domain; Region: Dak2; cl03685
568704001442	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK14481
568704001443	Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Region: DAK1; COG2376
568704001444	OsmC-like protein; Region: OsmC; cl00767
568704001445	Rhomboid family; Region: Rhomboid; cl11446
568704001446	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
568704001447	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
568704001448	active site
568704001449	catalytic site [active]
568704001450	substrate binding site [chemical binding]; other site
568704001451	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041; cl17396
568704001452	RelB antitoxin; Region: RelB; cl01171
568704001453	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
568704001454	dimerization interface [polypeptide binding]; other site
568704001455	putative DNA binding site [nucleotide binding]; other site
568704001456	putative Zn2+ binding site [ion binding]; other site
568704001457	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704001458	benzoate transport; Region: 2A0115; TIGR00895
568704001459	putative substrate translocation pore; other site
568704001460	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
568704001461	Predicted site-specific integrase-resolvase [DNA replication, recombination, and repair]; Region: COG2452
568704001462	Helix-Turn-Helix DNA binding domain of truncated MerR-like proteins; Region: HTH_MerR-trunc; cd04762
568704001463	DNA binding residues [nucleotide binding]
568704001464	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cl02788
568704001465	catalytic residues [active]
568704001466	catalytic nucleophile [active]
568704001467	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
568704001468	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
568704001469	Probable transposase; Region: OrfB_IS605; pfam01385
568704001470	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
568704001471	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
568704001472	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
568704001473	intersubunit interface [polypeptide binding]; other site
568704001474	active site
568704001475	zinc binding site [ion binding]; other site
568704001476	Na+ binding site [ion binding]; other site
568704001477	pyruvate oxidase; Provisional; Region: PRK08611
568704001478	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
568704001479	PYR/PP interface [polypeptide binding]; other site
568704001480	dimer interface [polypeptide binding]; other site
568704001481	tetramer interface [polypeptide binding]; other site
568704001482	TPP binding site [chemical binding]; other site
568704001483	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
568704001484	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
568704001485	TPP-binding site [chemical binding]; other site
568704001486	Beta-lactamase; Region: Beta-lactamase; pfam00144
568704001487	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
568704001488	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
568704001489	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
568704001490	active site
568704001491	Methyltransferase domain; Region: Methyltransf_31; pfam13847
568704001492	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568704001493	S-adenosylmethionine binding site [chemical binding]; other site
568704001494	Predicted glutamine amidotransferases [General function prediction only]; Region: COG2071
568704001495	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
568704001496	catalytic triad [active]
568704001497	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
568704001498	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
568704001499	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
568704001500	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
568704001501	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
568704001502	Amino acid permease; Region: AA_permease_2; pfam13520
568704001503	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
568704001504	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
568704001505	DNA binding residues [nucleotide binding]
568704001506	putative dimer interface [polypeptide binding]; other site
568704001507	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
568704001508	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
568704001509	active site
568704001510	catalytic tetrad [active]
568704001511	Arginate lyase and other MDR family members; Region: AL_MDR; cd08252
568704001512	zinc-binding alcohol dehydrogenase family protein; Region: adh_fam_1; TIGR02817
568704001513	putative NAD(P) binding site [chemical binding]; other site
568704001514	dimer interface [polypeptide binding]; other site
568704001515	Predicted transcriptional regulators [Transcription]; Region: COG1733
568704001516	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
568704001517	hypothetical protein; Provisional; Region: PRK10621
568704001518	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
568704001519	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
568704001520	gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Region: galliderm_ABC; TIGR03740
568704001521	Walker A/P-loop; other site
568704001522	ATP binding site [chemical binding]; other site
568704001523	Q-loop/lid; other site
568704001524	ABC transporter signature motif; other site
568704001525	Walker B; other site
568704001526	D-loop; other site
568704001527	H-loop/switch region; other site
568704001528	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
568704001529	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568704001530	active site
568704001531	phosphorylation site [posttranslational modification]
568704001532	intermolecular recognition site; other site
568704001533	dimerization interface [polypeptide binding]; other site
568704001534	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
568704001535	DNA binding site [nucleotide binding]
568704001536	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
568704001537	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
568704001538	dimerization interface [polypeptide binding]; other site
568704001539	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
568704001540	dimer interface [polypeptide binding]; other site
568704001541	phosphorylation site [posttranslational modification]
568704001542	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568704001543	ATP binding site [chemical binding]; other site
568704001544	Mg2+ binding site [ion binding]; other site
568704001545	G-X-G motif; other site
568704001546	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
568704001547	ABC-type multidrug transport system, ATPase component; Region: ABC_drug_resistance_like; cd03264
568704001548	Walker A/P-loop; other site
568704001549	ATP binding site [chemical binding]; other site
568704001550	Q-loop/lid; other site
568704001551	ABC transporter signature motif; other site
568704001552	Walker B; other site
568704001553	D-loop; other site
568704001554	H-loop/switch region; other site
568704001555	Aminopeptidase N [Amino acid transport and metabolism]; Region: PepN; COG0308
568704001556	Peptidase M1 Aminopeptidase N family incudes tricorn interacting factor F3, Endoplasmic reticulum aminopeptidase 1 (ERAP1), Aminopeptidase Q (APQ); Region: M1_APN_2; cd09601
568704001557	Zn binding site [ion binding]; other site
568704001558	inner membrane transporter YjeM; Provisional; Region: PRK15238
568704001559	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
568704001560	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
568704001561	Protein of unknown function (DUF1440); Region: DUF1440; pfam07274
568704001562	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
568704001563	proposed active site lysine [active]
568704001564	conserved cys residue [active]
568704001565	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
568704001566	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
568704001567	dimer interface [polypeptide binding]; other site
568704001568	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568704001569	catalytic residue [active]
568704001570	Cys/Met metabolism PLP-dependent enzyme; Region: Cys_Met_Meta_PP; pfam01053
568704001571	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
568704001572	homodimer interface [polypeptide binding]; other site
568704001573	substrate-cofactor binding pocket; other site
568704001574	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568704001575	catalytic residue [active]
568704001576	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
568704001577	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
568704001578	substrate binding pocket [chemical binding]; other site
568704001579	membrane-bound complex binding site; other site
568704001580	hinge residues; other site
568704001581	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
568704001582	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568704001583	dimer interface [polypeptide binding]; other site
568704001584	conserved gate region; other site
568704001585	putative PBP binding loops; other site
568704001586	ABC-ATPase subunit interface; other site
568704001587	Branched-chain amino acid transport protein; Region: Branch_AA_trans; cl00547
568704001588	WxL domain surface cell wall-binding; Region: WxL; pfam13731
568704001589	Bacterial protein of unknown function (DUF916); Region: DUF916; pfam06030
568704001590	Protein of unknown function C-terminal (DUF3324); Region: DUF3324; pfam11797
568704001591	legume lectins; Region: lectin_L-type; cd01951
568704001592	homotetramer interaction site [polypeptide binding]; other site
568704001593	carbohydrate binding site [chemical binding]; other site
568704001594	metal binding site [ion binding]; metal-binding site
568704001595	WxL domain surface cell wall-binding; Region: WxL; pfam13731
568704001596	WxL domain surface cell wall-binding; Region: WxL; pfam13731
568704001597	WxL domain surface cell wall-binding; Region: WxL; pfam13731
568704001598	legume lectins; Region: lectin_L-type; cd01951
568704001599	homotetramer interaction site [polypeptide binding]; other site
568704001600	carbohydrate binding site [chemical binding]; other site
568704001601	metal binding site [ion binding]; metal-binding site
568704001602	WxL domain surface cell wall-binding; Region: WxL; pfam13731
568704001603	EamA-like transporter family; Region: EamA; pfam00892
568704001604	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
568704001605	EamA-like transporter family; Region: EamA; pfam00892
568704001606	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
568704001607	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
568704001608	Walker A/P-loop; other site
568704001609	ATP binding site [chemical binding]; other site
568704001610	Q-loop/lid; other site
568704001611	ABC transporter signature motif; other site
568704001612	Walker B; other site
568704001613	D-loop; other site
568704001614	H-loop/switch region; other site
568704001615	ECF-type riboflavin transporter, S component; Region: ECF-ribofla_trS; cl17272
568704001616	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
568704001617	substrate binding site [chemical binding]; other site
568704001618	ATP binding site [chemical binding]; other site
568704001619	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
568704001620	FAD binding site [chemical binding]; other site
568704001621	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
568704001622	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
568704001623	THF binding site; other site
568704001624	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
568704001625	substrate binding site [chemical binding]; other site
568704001626	THF binding site; other site
568704001627	zinc-binding site [ion binding]; other site
568704001628	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
568704001629	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
568704001630	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
568704001631	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704001632	Walker A/P-loop; other site
568704001633	ATP binding site [chemical binding]; other site
568704001634	Q-loop/lid; other site
568704001635	ABC transporter signature motif; other site
568704001636	Walker B; other site
568704001637	D-loop; other site
568704001638	H-loop/switch region; other site
568704001639	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
568704001640	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
568704001641	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
568704001642	Walker A/P-loop; other site
568704001643	ATP binding site [chemical binding]; other site
568704001644	Q-loop/lid; other site
568704001645	ABC transporter signature motif; other site
568704001646	Walker B; other site
568704001647	D-loop; other site
568704001648	H-loop/switch region; other site
568704001649	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
568704001650	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704001651	putative substrate translocation pore; other site
568704001652	trehalose operon repressor, B. subtilis-type; Region: trehalos_R_Bsub; TIGR02404
568704001653	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568704001654	DNA-binding site [nucleotide binding]; DNA binding site
568704001655	UTRA domain; Region: UTRA; pfam07702
568704001656	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
568704001657	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
568704001658	Ca binding site [ion binding]; other site
568704001659	active site
568704001660	catalytic site [active]
568704001661	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
568704001662	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
568704001663	HPr interaction site; other site
568704001664	glycerol kinase (GK) interaction site [polypeptide binding]; other site
568704001665	active site
568704001666	phosphorylation site [posttranslational modification]
568704001667	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
568704001668	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
568704001669	active site turn [active]
568704001670	phosphorylation site [posttranslational modification]
568704001671	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
568704001672	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
568704001673	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
568704001674	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
568704001675	amino acid transporter; Region: 2A0306; TIGR00909
568704001676	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
568704001677	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
568704001678	NAD binding site [chemical binding]; other site
568704001679	dimer interface [polypeptide binding]; other site
568704001680	tetramer (dimer of dimers) interface [polypeptide binding]; other site
568704001681	substrate binding site [chemical binding]; other site
568704001682	glutamate dehydrogenase; Provisional; Region: PRK09414
568704001683	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
568704001684	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
568704001685	NAD(P) binding site [chemical binding]; other site
568704001686	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
568704001687	DNA-binding site [nucleotide binding]; DNA binding site
568704001688	RNA-binding motif; other site
568704001689	Transposase; Region: DEDD_Tnp_IS110; pfam01548
568704001690	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
568704001691	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
568704001692	Protein of unknown function (DUF3036); Region: DUF3036; pfam11234
568704001693	OsmC-like protein; Region: OsmC; pfam02566
568704001694	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
568704001695	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
568704001696	ABC transporter; Region: ABC_tran_2; pfam12848
568704001697	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
568704001698	atypical (a) SDRs, subgroup 5; Region: SDR_a5; cd05243
568704001699	NADH(P)-binding; Region: NAD_binding_10; pfam13460
568704001700	NAD(P) binding site [chemical binding]; other site
568704001701	putative active site [active]
568704001702	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
568704001703	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
568704001704	active site
568704001705	catalytic tetrad [active]
568704001706	putative transport protein YifK; Provisional; Region: PRK10746
568704001707	Protein of unknown function (DUF3800); Region: DUF3800; pfam12686
568704001708	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
568704001709	Protein of unknown function (DUF3021); Region: DUF3021; pfam11457
568704001710	LytTr DNA-binding domain; Region: LytTR; smart00850
568704001711	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
568704001712	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704001713	Walker A/P-loop; other site
568704001714	ATP binding site [chemical binding]; other site
568704001715	Q-loop/lid; other site
568704001716	ABC transporter signature motif; other site
568704001717	Walker B; other site
568704001718	D-loop; other site
568704001719	H-loop/switch region; other site
568704001720	Alpha/beta hydrolase of unknown function (DUF915); Region: DUF915; pfam06028
568704001721	Carbonic anhydrase alpha, prokaryotic-like subfamily. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon...; Region: alpha_CA_prokaryotic_like; cd03124
568704001722	active site
568704001723	zinc binding site [ion binding]; other site
568704001724	hypothetical protein; Provisional; Region: PRK00967
568704001725	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
568704001726	nudix motif; other site
568704001727	alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases; Region: MDR_like_2; cd05289
568704001728	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
568704001729	putative NAD(P) binding site [chemical binding]; other site
568704001730	Ammonia permease [Inorganic ion transport and metabolism]; Region: AmtB; COG0004
568704001731	Dyp-type peroxidase family; Region: Dyp_perox; cl01067
568704001732	Uncharacterized membrane protein [Function unknown]; Region: SapB; COG1285
568704001733	MgtC family; Region: MgtC; pfam02308
568704001734	DNA/RNA non-specific endonuclease; Region: Endonuclea_NS_2; pfam13930
568704001735	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
568704001736	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704001737	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
568704001738	Walker A/P-loop; other site
568704001739	ATP binding site [chemical binding]; other site
568704001740	Q-loop/lid; other site
568704001741	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
568704001742	ABC transporter; Region: ABC_tran_2; pfam12848
568704001743	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
568704001744	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704001745	Walker A/P-loop; other site
568704001746	ATP binding site [chemical binding]; other site
568704001747	Q-loop/lid; other site
568704001748	ABC transporter signature motif; other site
568704001749	Walker B; other site
568704001750	D-loop; other site
568704001751	H-loop/switch region; other site
568704001752	Uncharacterized subfamily of Uracil-DNA glycosylases; Region: UDG_like_1; cd10033
568704001753	putative uracil binding site [chemical binding]; other site
568704001754	putative active site [active]
568704001755	Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism]; Region: GlpF; COG0580
568704001756	amphipathic channel; other site
568704001757	Asn-Pro-Ala signature motifs; other site
568704001758	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GlpA; COG0578
568704001759	glycerol kinase; Provisional; Region: glpK; PRK00047
568704001760	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
568704001761	N- and C-terminal domain interface [polypeptide binding]; other site
568704001762	active site
568704001763	MgATP binding site [chemical binding]; other site
568704001764	catalytic site [active]
568704001765	metal binding site [ion binding]; metal-binding site
568704001766	glycerol binding site [chemical binding]; other site
568704001767	homotetramer interface [polypeptide binding]; other site
568704001768	homodimer interface [polypeptide binding]; other site
568704001769	FBP binding site [chemical binding]; other site
568704001770	protein IIAGlc interface [polypeptide binding]; other site
568704001771	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
568704001772	active site
568704001773	CAT RNA binding domain; Region: CAT_RBD; pfam03123
568704001774	transcriptional antiterminator BglG; Provisional; Region: PRK09772
568704001775	PRD domain; Region: PRD; pfam00874
568704001776	PRD domain; Region: PRD; pfam00874
568704001777	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; cl17295
568704001778	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
568704001779	PTS_IIB_lactose: subunit IIB of enzyme II (EII) of the lactose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS) found in Firmicutes as well as Actinobacteria. In this system, EII is a lactose-specific permease with two...; Region: PTS_IIB_lactose; cd05565
568704001780	active site
568704001781	P-loop; other site
568704001782	phosphorylation site [posttranslational modification]
568704001783	6-phospho-beta-galactosidase; Provisional; Region: PRK13511
568704001784	beta-galactosidase; Region: BGL; TIGR03356
568704001785	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cl00166
568704001786	methionine cluster; other site
568704001787	active site
568704001788	phosphorylation site [posttranslational modification]
568704001789	metal binding site [ion binding]; metal-binding site
568704001790	galactokinase; Provisional; Region: PRK05322
568704001791	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
568704001792	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
568704001793	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
568704001794	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
568704001795	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
568704001796	NAD binding site [chemical binding]; other site
568704001797	homodimer interface [polypeptide binding]; other site
568704001798	active site
568704001799	substrate binding site [chemical binding]; other site
568704001800	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK05270
568704001801	Galactose-1-phosphate uridyl transferase, N-terminal domain; Region: GalP_UDP_transf; pfam01087
568704001802	Galactose-1-phosphate uridyl transferase, C-terminal domain; Region: GalP_UDP_tr_C; pfam02744
568704001803	Transcriptional regulators [Transcription]; Region: PurR; COG1609
568704001804	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
568704001805	DNA binding site [nucleotide binding]
568704001806	domain linker motif; other site
568704001807	Ligand-binding domain of DNA transcription repressor GalR which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalR; cd01544
568704001808	putative dimerization interface [polypeptide binding]; other site
568704001809	putative ligand binding site [chemical binding]; other site
568704001810	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
568704001811	active site
568704001812	catalytic residues [active]
568704001813	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
568704001814	active site
568704001815	phosphorylation site [posttranslational modification]
568704001816	Phosphotransferase system, galactitol-specific IIB component [Carbohydrate transport and metabolism]; Region: SgaB; COG3414
568704001817	active site
568704001818	P-loop; other site
568704001819	phosphorylation site [posttranslational modification]
568704001820	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
568704001821	PTS system sugar-specific permease component; Region: EIIC-GAT; pfam03611
568704001822	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
568704001823	Beta-lactamase; Region: Beta-lactamase; pfam00144
568704001824	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
568704001825	tagatose-6-phosphate kinase; Region: lacC; TIGR01231
568704001826	putative substrate binding site [chemical binding]; other site
568704001827	putative ATP binding site [chemical binding]; other site
568704001828	tagatose 1,6-diphosphate aldolase; Reviewed; Region: PRK12399
568704001829	galactose-6-phosphate isomerase subunit LacB; Reviewed; Region: PRK08622
568704001830	galactose-6-phosphate isomerase subunit LacA; Reviewed; Region: PRK08621
568704001831	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
568704001832	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
568704001833	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
568704001834	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
568704001835	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568704001836	active site
568704001837	motif I; other site
568704001838	motif II; other site
568704001839	DNA repair exonuclease [DNA replication, recombination, and repair]; Region: SbcD; COG0420
568704001840	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
568704001841	active site
568704001842	metal binding site [ion binding]; metal-binding site
568704001843	DNA binding site [nucleotide binding]
568704001844	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
568704001845	ATP-binding cassette domain of sbcCD; Region: ABC_sbcCD; cd03279
568704001846	AAA domain; Region: AAA_23; pfam13476
568704001847	Walker A/P-loop; other site
568704001848	ATP binding site [chemical binding]; other site
568704001849	Q-loop/lid; other site
568704001850	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: SbcC; COG0419
568704001851	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704001852	ABC transporter signature motif; other site
568704001853	Walker B; other site
568704001854	D-loop; other site
568704001855	H-loop/switch region; other site
568704001856	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
568704001857	Group of bacterial proteins containing an alpha crystallin domain (ACD) similar to Lactobacillus plantarum (Lp) small heat shock proteins (sHsp) HSP 18.5, HSP 18.55 and HSP 19.3. sHsps are molecular chaperones that suppress protein aggregation and...; Region: ACD_LpsHSP_like; cd06471
568704001858	putative dimer interface [polypeptide binding]; other site
568704001859	A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; Region: MutY; COG1194
568704001860	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
568704001861	minor groove reading motif; other site
568704001862	helix-hairpin-helix signature motif; other site
568704001863	substrate binding pocket [chemical binding]; other site
568704001864	active site
568704001865	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
568704001866	DNA binding and oxoG recognition site [nucleotide binding]
568704001867	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
568704001868	Flavodoxin-like fold; Region: Flavodoxin_2; pfam02525
568704001869	Short repeat of unknown function (DUF308); Region: DUF308; pfam03729
568704001870	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
568704001871	dimer interface [polypeptide binding]; other site
568704001872	substrate binding site [chemical binding]; other site
568704001873	ATP binding site [chemical binding]; other site
568704001874	biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs; Region: BVR-B_like_SDR_a; cd05244
568704001875	NADH(P)-binding; Region: NAD_binding_10; pfam13460
568704001876	NAD binding site [chemical binding]; other site
568704001877	substrate binding site [chemical binding]; other site
568704001878	putative active site [active]
568704001879	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
568704001880	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
568704001881	Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915
568704001882	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
568704001883	Type I periplasmic ligand-binding domain of uncharacterized ABC-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_uncharacterized_transporter; cd06325
568704001884	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
568704001885	zinc binding site [ion binding]; other site
568704001886	putative ligand binding site [chemical binding]; other site
568704001887	Type I periplasmic ligand-binding domain of uncharacterized ABC-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_uncharacterized_transporter; cd06325
568704001888	zinc binding site [ion binding]; other site
568704001889	putative ligand binding site [chemical binding]; other site
568704001890	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
568704001891	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cd06574
568704001892	TM-ABC transporter signature motif; other site
568704001893	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: PhnK; COG1101
568704001894	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704001895	Walker A/P-loop; other site
568704001896	ATP binding site [chemical binding]; other site
568704001897	Q-loop/lid; other site
568704001898	ABC transporter signature motif; other site
568704001899	Walker B; other site
568704001900	D-loop; other site
568704001901	H-loop/switch region; other site
568704001902	Yhdh and yhfp-like putative quinone oxidoreductases; Region: MDR_yhdh_yhfp; cd05280
568704001903	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
568704001904	NADP binding site [chemical binding]; other site
568704001905	dimer interface [polypeptide binding]; other site
568704001906	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
568704001907	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
568704001908	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
568704001909	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
568704001910	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568704001911	motif II; other site
568704001912	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
568704001913	Transposase; Region: DEDD_Tnp_IS110; pfam01548
568704001914	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
568704001915	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
568704001916	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
568704001917	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
568704001918	Ligand binding site; other site
568704001919	Putative Catalytic site; other site
568704001920	DXD motif; other site
568704001921	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
568704001922	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
568704001923	Predicted membrane protein [Function unknown]; Region: COG2246
568704001924	GtrA-like protein; Region: GtrA; pfam04138
568704001925	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
568704001926	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568704001927	active site
568704001928	phosphorylation site [posttranslational modification]
568704001929	intermolecular recognition site; other site
568704001930	dimerization interface [polypeptide binding]; other site
568704001931	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
568704001932	DNA binding site [nucleotide binding]
568704001933	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
568704001934	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
568704001935	dimer interface [polypeptide binding]; other site
568704001936	phosphorylation site [posttranslational modification]
568704001937	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568704001938	ATP binding site [chemical binding]; other site
568704001939	Mg2+ binding site [ion binding]; other site
568704001940	G-X-G motif; other site
568704001941	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4918
568704001942	Nitroreductase-like family 1. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_1; cd02137
568704001943	dimer interface [polypeptide binding]; other site
568704001944	FMN binding site [chemical binding]; other site
568704001945	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
568704001946	FMN-dependent dehydrogenase; Region: FMN_dh; pfam01070
568704001947	phosphate binding site [ion binding]; other site
568704001948	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
568704001949	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
568704001950	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
568704001951	Int/Topo IB signature motif; other site
568704001952	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568704001953	non-specific DNA binding site [nucleotide binding]; other site
568704001954	salt bridge; other site
568704001955	sequence-specific DNA binding site [nucleotide binding]; other site
568704001956	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568704001957	non-specific DNA binding site [nucleotide binding]; other site
568704001958	salt bridge; other site
568704001959	sequence-specific DNA binding site [nucleotide binding]; other site
568704001960	Helix-turn-helix domain; Region: HTH_17; pfam12728
568704001961	Prim_Pol: Primase-polymerase (primpol) domain of the type found in bifunctional replicases from archaeal plasmids, including ORF904 protein of the crenarchaeal plasmid pRN1 from Sulfolobus islandicus (pRN1 primpol). These primpol domains belong to the...; Region: Prim_Pol; cd04859
568704001962	polymerase nucleotide-binding site; other site
568704001963	DNA-binding residues [nucleotide binding]; DNA binding site
568704001964	nucleotide binding site [chemical binding]; other site
568704001965	primase nucleotide-binding site [nucleotide binding]; other site
568704001966	Primase C terminal 1 (PriCT-1); Region: PriCT_1; smart00942
568704001967	Virulence-associated protein E; Region: VirE; pfam05272
568704001968	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
568704001969	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
568704001970	active site
568704001971	Phage terminase, small subunit; Region: Terminase_4; pfam05119
568704001972	Phage Terminase; Region: Terminase_1; pfam03354
568704001973	Phage portal protein; Region: Phage_portal; pfam04860
568704001974	Phage-related protein [Function unknown]; Region: COG4695; cl01923
568704001975	Caudovirus prohead protease; Region: Peptidase_U35; pfam04586
568704001976	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
568704001977	Phage capsid family; Region: Phage_capsid; pfam05065
568704001978	Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; Region: gp6; cd08054
568704001979	oligomerization interface [polypeptide binding]; other site
568704001980	Phage head-tail joining protein; Region: Phage_H_T_join; cl11461
568704001981	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
568704001982	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568704001983	non-specific DNA binding site [nucleotide binding]; other site
568704001984	salt bridge; other site
568704001985	sequence-specific DNA binding site [nucleotide binding]; other site
568704001986	Helix-turn-helix domain; Region: HTH_19; pfam12844
568704001987	Predicted transcriptional regulators [Transcription]; Region: COG1695
568704001988	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
568704001989	Sugar efflux transporter for intercellular exchange; Region: MtN3_slv; pfam03083
568704001990	zinc-binding alcohol dehydrogenase family protein; Region: adh_fam_1; TIGR02817
568704001991	Arginate lyase and other MDR family members; Region: AL_MDR; cd08252
568704001992	putative NAD(P) binding site [chemical binding]; other site
568704001993	dimer interface [polypeptide binding]; other site
568704001994	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
568704001995	Domain of unknown function DUF20; Region: UPF0118; pfam01594
568704001996	LexA repressor; Validated; Region: PRK00215
568704001997	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
568704001998	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
568704001999	Catalytic site [active]
568704002000	Membrane transport protein; Region: Mem_trans; pfam03547
568704002001	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
568704002002	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
568704002003	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
568704002004	Uncharacterized conserved protein [Function unknown]; Region: COG3189
568704002005	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
568704002006	uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u2; cd12827
568704002007	Cl binding site [ion binding]; other site
568704002008	oligomer interface [polypeptide binding]; other site
568704002009	Transcriptional regulator [Transcription]; Region: LysR; COG0583
568704002010	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568704002011	The substrate binding domain of LysR-type transcriptional regulator MleR which required for malolactic fermentation, contains type 2 periplasmic binidning fold; Region: PBP2_MleR; cd08437
568704002012	putative dimerization interface [polypeptide binding]; other site
568704002013	malate dehydrogenase; Provisional; Region: PRK13529
568704002014	Malic enzyme, N-terminal domain; Region: malic; pfam00390
568704002015	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
568704002016	NAD(P) binding site [chemical binding]; other site
568704002017	Membrane transport protein; Region: Mem_trans; cl09117
568704002018	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
568704002019	dimer interface [polypeptide binding]; other site
568704002020	catalytic triad [active]
568704002021	peroxidatic and resolving cysteines [active]
568704002022	Flavodoxin domain; Region: Flavodoxin_5; cl17428
568704002023	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
568704002024	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568704002025	non-specific DNA binding site [nucleotide binding]; other site
568704002026	salt bridge; other site
568704002027	sequence-specific DNA binding site [nucleotide binding]; other site
568704002028	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
568704002029	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
568704002030	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
568704002031	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
568704002032	Walker A/P-loop; other site
568704002033	ATP binding site [chemical binding]; other site
568704002034	Q-loop/lid; other site
568704002035	ABC transporter signature motif; other site
568704002036	Walker B; other site
568704002037	D-loop; other site
568704002038	H-loop/switch region; other site
568704002039	oligoendopeptidase F; Region: pepF; TIGR00181
568704002040	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_4; cd09609
568704002041	active site
568704002042	Zn binding site [ion binding]; other site
568704002043	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
568704002044	active site
568704002045	multimer interface [polypeptide binding]; other site
568704002046	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
568704002047	ATPase, P-type (transporting), HAD superfamily, subfamily IC; Region: ATPase_P-type; TIGR01494
568704002048	proline-specific peptidase, Bacillus coagulans-type subfamily; Region: pro_imino_pep_2; TIGR01250
568704002049	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
568704002050	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
568704002051	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
568704002052	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568704002053	motif II; other site
568704002054	HAD-hyrolase-like; Region: Hydrolase_like; pfam13242
568704002055	Transcriptional regulators [Transcription]; Region: MarR; COG1846
568704002056	MarR family; Region: MarR_2; pfam12802
568704002057	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
568704002058	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
568704002059	flavoprotein NrdI; Provisional; Region: PRK02551
568704002060	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
568704002061	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
568704002062	active site
568704002063	catalytic tetrad [active]
568704002064	Alpha/beta hydrolase of unknown function (DUF915); Region: DUF915; pfam06028
568704002065	Predicted membrane protein [Function unknown]; Region: COG2323
568704002066	Protein of unknown function (DUF3290); Region: DUF3290; pfam11694
568704002067	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
568704002068	substrate binding site [chemical binding]; other site
568704002069	zinc-binding site [ion binding]; other site
568704002070	S-ribosylhomocysteinase; Provisional; Region: PRK02260
568704002071	Uncharacterized conserved protein [Function unknown]; Region: COG0398
568704002072	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
568704002073	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
568704002074	RuvA N terminal domain; Region: RuvA_N; pfam01330
568704002075	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
568704002076	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568704002077	Walker A motif; other site
568704002078	ATP binding site [chemical binding]; other site
568704002079	Walker B motif; other site
568704002080	arginine finger; other site
568704002081	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
568704002082	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
568704002083	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
568704002084	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
568704002085	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
568704002086	Preprotein translocase subunit; Region: YajC; pfam02699
568704002087	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
568704002088	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
568704002089	putative catalytic cysteine [active]
568704002090	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
568704002091	putative active site [active]
568704002092	metal binding site [ion binding]; metal-binding site
568704002093	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
568704002094	Helix-turn-helix diphteria tox regulatory element; Region: HTH_DTXR; smart00529
568704002095	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
568704002096	FeoA domain; Region: FeoA; pfam04023
568704002097	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
568704002098	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
568704002099	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
568704002100	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
568704002101	active site
568704002102	DNA polymerase IV; Validated; Region: PRK02406
568704002103	DNA binding site [nucleotide binding]
568704002104	Predicted transcriptional regulator containing CBS domains [Transcription]; Region: COG4109
568704002105	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568704002106	DNA-binding site [nucleotide binding]; DNA binding site
568704002107	DRTGG domain; Region: DRTGG; pfam07085
568704002108	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
568704002109	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
568704002110	DHH family; Region: DHH; pfam01368
568704002111	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
568704002112	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
568704002113	ATP binding site [chemical binding]; other site
568704002114	Mg++ binding site [ion binding]; other site
568704002115	motif III; other site
568704002116	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
568704002117	nucleotide binding region [chemical binding]; other site
568704002118	ATP-binding site [chemical binding]; other site
568704002119	tRNA synthetases class II (A); Region: tRNA-synt_2c; pfam01411
568704002120	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
568704002121	motif 1; other site
568704002122	active site
568704002123	motif 2; other site
568704002124	motif 3; other site
568704002125	alanine-tRNA ligase; Region: PLN02961
568704002126	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
568704002127	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
568704002128	hypothetical protein; Provisional; Region: PRK05473
568704002129	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
568704002130	hypothetical protein; Provisional; Region: PRK13678
568704002131	Cell division protein ZapA; Region: ZapA; pfam05164
568704002132	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
568704002133	Colicin V production protein; Region: Colicin_V; pfam02674
568704002134	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
568704002135	MutS domain III; Region: MutS_III; pfam05192
568704002136	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704002137	Walker A/P-loop; other site
568704002138	ATP binding site [chemical binding]; other site
568704002139	Q-loop/lid; other site
568704002140	ABC transporter signature motif; other site
568704002141	Walker B; other site
568704002142	D-loop; other site
568704002143	H-loop/switch region; other site
568704002144	Smr domain; Region: Smr; pfam01713
568704002145	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
568704002146	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
568704002147	catalytic residues [active]
568704002148	D-Ala-teichoic acid biosynthesis protein; Region: DUF3687; pfam12459
568704002149	D-alanine--poly(phosphoribitol) ligase, subunit 1; Region: D-ala-DACP-lig; TIGR01734
568704002150	D-alanine:D-alanyl carrier protein ligase (DltA); Region: DltA; cd05945
568704002151	acyl-activating enzyme (AAE) consensus motif; other site
568704002152	AMP binding site [chemical binding]; other site
568704002153	D-alanyl-lipoteichoic acid biosynthesis protein DltB; Region: LTA_dltB; TIGR04091
568704002154	D-alanine--poly(phosphoribitol) ligase subunit 2; Validated; Region: PRK05087
568704002155	D-alanyl-lipoteichoic acid biosynthesis protein DltD; Region: LTA_DltD; TIGR04092
568704002156	DltD N-terminal region; Region: DltD_N; pfam04915
568704002157	DltD central region; Region: DltD_M; pfam04918
568704002158	DltD C-terminal region; Region: DltD_C; pfam04914
568704002159	Protein of unknown function (DUF2507); Region: DUF2507; pfam10702
568704002160	glutamate racemase; Provisional; Region: PRK00865
568704002161	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
568704002162	active site
568704002163	dimerization interface [polypeptide binding]; other site
568704002164	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
568704002165	active site
568704002166	metal binding site [ion binding]; metal-binding site
568704002167	homotetramer interface [polypeptide binding]; other site
568704002168	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
568704002169	amphipathic channel; other site
568704002170	Asn-Pro-Ala signature motifs; other site
568704002171	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_30; cd04643
568704002172	FOG: CBS domain [General function prediction only]; Region: COG0517
568704002173	Domain of unknown function (DUF368); Region: DUF368; pfam04018
568704002174	Mechanosensitive ion channel; Region: MS_channel; pfam00924
568704002175	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
568704002176	Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain [General function prediction only]; Region: COG4768
568704002177	YtxH-like protein; Region: YtxH; pfam12732
568704002178	Predicted small molecule binding protein (contains 3H domain) [General function prediction only]; Region: COG1827
568704002179	HTH domain; Region: HTH_11; pfam08279
568704002180	3H domain; Region: 3H; pfam02829
568704002181	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
568704002182	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
568704002183	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
568704002184	active site
568704002185	catabolite control protein A; Region: ccpA; TIGR01481
568704002186	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
568704002187	DNA binding site [nucleotide binding]
568704002188	domain linker motif; other site
568704002189	Ligand-binding domain of the catabolite control protein A (CcpA), which functions as the major transcriptional regulator of carbon catabolite repression/regulation; Region: PBP1_CcpA_like; cd06298
568704002190	dimerization interface [polypeptide binding]; other site
568704002191	effector binding site; other site
568704002192	Transglycosylase; Region: Transgly; pfam00912
568704002193	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
568704002194	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
568704002195	HAD superfamily (subfamily IA) hydrolase, TIGR02254; Region: YjjG/YfnB
568704002196	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568704002197	motif II; other site
568704002198	birA, biotin-[acetyl-CoA-carboxylase] ligase region; Region: birA_ligase; TIGR00121
568704002199	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
568704002200	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
568704002201	dipeptidase PepV; Reviewed; Region: PRK07318
568704002202	M20 Peptidase Xaa-His dipeptidase (PepV) degrades hydrophobic dipeptides; Region: M20_PepV; cd03888
568704002203	active site
568704002204	metal binding site [ion binding]; metal-binding site
568704002205	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
568704002206	Glycerophosphodiester phosphodiesterase domain as found in prokaryota and eukaryota, and similar proteins; Region: GDPD; cd08556
568704002207	active site
568704002208	catalytic site [active]
568704002209	metal binding site [ion binding]; metal-binding site
568704002210	YibE/F-like protein; Region: YibE_F; pfam07907
568704002211	YibE/F-like protein; Region: YibE_F; cl02259
568704002212	Aquifex aeolicus AQ1575 and related proteins, metallophosphatase domain; Region: MPP_AQ1575; cd07390
568704002213	putative active site [active]
568704002214	putative metal binding site [ion binding]; other site
568704002215	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
568704002216	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
568704002217	active site
568704002218	metal binding site [ion binding]; metal-binding site
568704002219	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
568704002220	Protein of unknown function (DUF1027); Region: DUF1027; pfam06265
568704002221	HAD-superfamily subfamily IIA hydrolase, TIGR01457; Region: HAD-SF-IIA-hyp2
568704002222	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568704002223	active site
568704002224	motif I; other site
568704002225	motif II; other site
568704002226	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568704002227	Protein of unknown function (DUF1461); Region: DUF1461; pfam07314
568704002228	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
568704002229	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
568704002230	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
568704002231	tetramer interfaces [polypeptide binding]; other site
568704002232	binuclear metal-binding site [ion binding]; other site
568704002233	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
568704002234	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
568704002235	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
568704002236	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cl00197
568704002237	active site
568704002238	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cd00164
568704002239	RNA binding site [nucleotide binding]; other site
568704002240	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
568704002241	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
568704002242	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
568704002243	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
568704002244	This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1; Region: GT1_UGDG_like; cd03817
568704002245	putative ADP-binding pocket [chemical binding]; other site
568704002246	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
568704002247	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
568704002248	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
568704002249	aromatic amino acid aminotransferase; Validated; Region: PRK07309
568704002250	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
568704002251	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568704002252	homodimer interface [polypeptide binding]; other site
568704002253	catalytic residue [active]
568704002254	Protein of unknown function (DUF1797); Region: DUF1797; pfam08796
568704002255	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
568704002256	Sulfatase; Region: Sulfatase; pfam00884
568704002257	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
568704002258	metal binding site 2 [ion binding]; metal-binding site
568704002259	putative DNA binding helix; other site
568704002260	metal binding site 1 [ion binding]; metal-binding site
568704002261	dimer interface [polypeptide binding]; other site
568704002262	structural Zn2+ binding site [ion binding]; other site
568704002263	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
568704002264	Int/Topo IB signature motif; other site
568704002265	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
568704002266	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
568704002267	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
568704002268	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
568704002269	Catalytic site [active]
568704002270	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
568704002271	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568704002272	non-specific DNA binding site [nucleotide binding]; other site
568704002273	salt bridge; other site
568704002274	sequence-specific DNA binding site [nucleotide binding]; other site
568704002275	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
568704002276	Catalytic site [active]
568704002277	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
568704002278	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568704002279	non-specific DNA binding site [nucleotide binding]; other site
568704002280	salt bridge; other site
568704002281	sequence-specific DNA binding site [nucleotide binding]; other site
568704002282	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
568704002283	Phage antirepressor protein KilAC domain; Region: ANT; pfam03374
568704002284	Domain of unknown function (DUF771); Region: DUF771; pfam05595
568704002285	RecT family; Region: RecT; pfam03837
568704002286	PDDEXK-like domain of unknown function (DUF3799); Region: DUF3799; pfam12684
568704002287	DnaD and phage-associated domain; Region: DnaD_dom; TIGR01446
568704002288	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
568704002289	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
568704002290	dimer interface [polypeptide binding]; other site
568704002291	ssDNA binding site [nucleotide binding]; other site
568704002292	tetramer (dimer of dimers) interface [polypeptide binding]; other site
568704002293	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
568704002294	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568704002295	non-specific DNA binding site [nucleotide binding]; other site
568704002296	salt bridge; other site
568704002297	sequence-specific DNA binding site [nucleotide binding]; other site
568704002298	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568704002299	non-specific DNA binding site [nucleotide binding]; other site
568704002300	salt bridge; other site
568704002301	sequence-specific DNA binding site [nucleotide binding]; other site
568704002302	Protein of unknown function (DUF1642); Region: DUF1642; pfam07852
568704002303	YopX protein; Region: YopX; pfam09643
568704002304	GcrA cell cycle regulator; Region: GcrA; cl11564
568704002305	NUMOD4 motif; Region: NUMOD4; pfam07463
568704002306	HNH endonuclease; Region: HNH_3; pfam13392
568704002307	GIYX(10-11)YIG family of class I homing endonucleases C-terminus (GIY-YIG_Cterm). Homing endonucleases promote the mobility of intron or intein by recognizing and cleaving a homologous allele that lacks the sequence. They catalyze a double-strand break...; Region: GIY-YIG_Cterm; cl11508
568704002308	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
568704002309	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
568704002310	active site
568704002311	AAA domain; Region: AAA_33; pfam13671
568704002312	AAA domain; Region: AAA_17; pfam13207
568704002313	Phage terminase, small subunit; Region: Terminase_4; pfam05119
568704002314	Phage Terminase; Region: Terminase_1; pfam03354
568704002315	phage portal protein, HK97 family; Region: portal_HK97; TIGR01537
568704002316	Phage-related protein [Function unknown]; Region: COG4695; cl01923
568704002317	Caudovirus prohead protease; Region: Peptidase_U35; pfam04586
568704002318	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
568704002319	Phage capsid family; Region: Phage_capsid; pfam05065
568704002320	Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; Region: gp6; cd08054
568704002321	oligomerization interface [polypeptide binding]; other site
568704002322	Phage head-tail joining protein; Region: Phage_H_T_join; pfam05521
568704002323	phage protein, HK97 gp10 family; Region: phge_HK97_gp10; TIGR01725
568704002324	phage major tail protein, phi13 family; Region: maj_tail_phi13; TIGR01603
568704002325	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
568704002326	putative phage tail component, N-terminal domain; Region: phi3626_gp14_N; TIGR01633
568704002327	Phage tail protein; Region: Sipho_tail; cl17486
568704002328	Phage tail protein; Region: Sipho_tail; cl17486
568704002329	Bacteriophage holin; Region: Phage_holin_1; pfam04531
568704002330	Endo-N-acetylmuramidases (muramidases) are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues; Region: GH25_muramidase; cl10448
568704002331	active site
568704002332	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
568704002333	Bacterial SH3 domain; Region: SH3_5; pfam08460
568704002334	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
568704002335	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
568704002336	S-adenosylmethionine synthetase; Validated; Region: PRK05250
568704002337	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
568704002338	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
568704002339	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
568704002340	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704002341	Major Facilitator Superfamily; Region: MFS_1; pfam07690
568704002342	putative substrate translocation pore; other site
568704002343	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704002344	Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators; Region: HTH_GlnR-like; cd01105
568704002345	DNA binding residues [nucleotide binding]
568704002346	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
568704002347	putative dimer interface [polypeptide binding]; other site
568704002348	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
568704002349	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704002350	putative substrate translocation pore; other site
568704002351	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704002352	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
568704002353	active site
568704002354	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
568704002355	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
568704002356	HIGH motif; other site
568704002357	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
568704002358	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
568704002359	active site
568704002360	KMSKS motif; other site
568704002361	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
568704002362	tRNA binding surface [nucleotide binding]; other site
568704002363	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
568704002364	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
568704002365	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
568704002366	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
568704002367	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
568704002368	RNA binding surface [nucleotide binding]; other site
568704002369	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
568704002370	active site
568704002371	uracil binding [chemical binding]; other site
568704002372	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082); Region: DUF2082; pfam09855
568704002373	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
568704002374	putative substrate binding site [chemical binding]; other site
568704002375	putative ATP binding site [chemical binding]; other site
568704002376	Contains a crystal structure of the Nudix hydrolase from Enterococcus faecalis, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_25; cd04684
568704002377	nudix motif; other site
568704002378	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
568704002379	catalytic residues [active]
568704002380	dimer interface [polypeptide binding]; other site
568704002381	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
568704002382	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
568704002383	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568704002384	homodimer interface [polypeptide binding]; other site
568704002385	catalytic residue [active]
568704002386	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
568704002387	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
568704002388	active site
568704002389	metal binding site [ion binding]; metal-binding site
568704002390	ACT domain proteins similar to the yet uncharacterized Streptococcus pneumoniae ACT domain protein; Region: ACT_1ZPV; cd04872
568704002391	Uncharacterized proteins with similarity to Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL_like_DUF711; cd08025
568704002392	Competence protein CoiA-like family; Region: CoiA; cl11541
568704002393	Thioredoxin; Region: Thioredoxin_5; pfam13743
568704002394	Uncharacterized subgroup 1 of the CYTH-like superfamily; Region: CYTH-like_Pase_1; cd07762
568704002395	putative active site [active]
568704002396	putative metal binding residues [ion binding]; other site
568704002397	signature motif; other site
568704002398	putative triphosphate binding site [ion binding]; other site
568704002399	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
568704002400	synthetase active site [active]
568704002401	NTP binding site [chemical binding]; other site
568704002402	metal binding site [ion binding]; metal-binding site
568704002403	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK04885
568704002404	ATP-NAD kinase; Region: NAD_kinase; pfam01513
568704002405	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
568704002406	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
568704002407	RNA binding surface [nucleotide binding]; other site
568704002408	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
568704002409	active site
568704002410	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
568704002411	ApbE family; Region: ApbE; pfam02424
568704002412	Uncharacterized protein involved in copper resistance [Inorganic ion transport and metabolism]; Region: CutC; COG3142
568704002413	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
568704002414	Lactonase, 7-bladed beta-propeller; Region: Lactonase; pfam10282
568704002415	PTS system glucitol/sorbitol-specific IIA component; Region: PTSIIA_gutA; cl01516
568704002416	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
568704002417	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05458
568704002418	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
568704002419	active site
568704002420	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
568704002421	metal ion transporter CorA-like divalent cation transporter superfamily; Region: MIT_CorA-like; cl00459
568704002422	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
568704002423	uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u2; cd12827
568704002424	Cl binding site [ion binding]; other site
568704002425	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
568704002426	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568704002427	S-adenosylmethionine binding site [chemical binding]; other site
568704002428	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
568704002429	Protein of unknown function (DUF1149); Region: DUF1149; pfam06619
568704002430	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
568704002431	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
568704002432	This domain directs oriented DNA translocation and forms a winged helix structure; Region: Ftsk_gamma; smart00843
568704002433	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
568704002434	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
568704002435	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
568704002436	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
568704002437	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
568704002438	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
568704002439	classical (c) SDRs; Region: SDR_c; cd05233
568704002440	NAD(P) binding site [chemical binding]; other site
568704002441	active site
568704002442	Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown]; Region: COG1426
568704002443	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568704002444	non-specific DNA binding site [nucleotide binding]; other site
568704002445	salt bridge; other site
568704002446	sequence-specific DNA binding site [nucleotide binding]; other site
568704002447	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
568704002448	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
568704002449	competence damage-inducible protein A; Provisional; Region: PRK00549
568704002450	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
568704002451	putative MPT binding site; other site
568704002452	Uncharacterized protein (competence- and mitomycin-induced) [General function prediction only]; Region: CinA; COG1546
568704002453	recombinase A; Provisional; Region: recA; PRK09354
568704002454	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
568704002455	hexamer interface [polypeptide binding]; other site
568704002456	Walker A motif; other site
568704002457	ATP binding site [chemical binding]; other site
568704002458	Walker B motif; other site
568704002459	ribonuclease Y; Region: RNase_Y; TIGR03319
568704002460	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
568704002461	Zn2+ binding site [ion binding]; other site
568704002462	Mg2+ binding site [ion binding]; other site
568704002463	Uncharacterized conserved protein [Function unknown]; Region: COG1739
568704002464	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
568704002465	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
568704002466	Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein) [DNA replication, recombination, and repair]; Region: comFA; COG4098
568704002467	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
568704002468	ATP binding site [chemical binding]; other site
568704002469	putative Mg++ binding site [ion binding]; other site
568704002470	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
568704002471	nucleotide binding region [chemical binding]; other site
568704002472	ATP-binding site [chemical binding]; other site
568704002473	comF family protein; Region: comF; TIGR00201
568704002474	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
568704002475	30S subunit binding site; other site
568704002476	preprotein translocase subunit SecA; Reviewed; Region: secA; PRK12906
568704002477	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
568704002478	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
568704002479	nucleotide binding region [chemical binding]; other site
568704002480	ATP-binding site [chemical binding]; other site
568704002481	peptide chain release factor 2; Provisional; Region: PRK05589
568704002482	This domain is found in peptide chain release factors; Region: PCRF; smart00937
568704002483	RF-1 domain; Region: RF-1; pfam00472
568704002484	Predicted ATPase involved in cell division [Cell division and chromosome partitioning]; Region: FtsE; COG2884
568704002485	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704002486	Walker A/P-loop; other site
568704002487	ATP binding site [chemical binding]; other site
568704002488	Q-loop/lid; other site
568704002489	ABC transporter signature motif; other site
568704002490	Walker B; other site
568704002491	D-loop; other site
568704002492	H-loop/switch region; other site
568704002493	Cell division protein [Cell division and chromosome partitioning]; Region: FtsX; COG2177
568704002494	Cell division protein [Cell division and chromosome partitioning]; Region: FtsX; COG2177
568704002495	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
568704002496	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
568704002497	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
568704002498	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568704002499	active site
568704002500	phosphorylation site [posttranslational modification]
568704002501	intermolecular recognition site; other site
568704002502	dimerization interface [polypeptide binding]; other site
568704002503	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
568704002504	DNA binding site [nucleotide binding]
568704002505	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: VicK; COG5002
568704002506	PAS domain; Region: PAS_8; pfam13188
568704002507	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
568704002508	dimer interface [polypeptide binding]; other site
568704002509	phosphorylation site [posttranslational modification]
568704002510	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568704002511	ATP binding site [chemical binding]; other site
568704002512	Mg2+ binding site [ion binding]; other site
568704002513	G-X-G motif; other site
568704002514	PBP superfamily domain; Region: PBP_like_2; cl17296
568704002515	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
568704002516	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573
568704002517	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568704002518	dimer interface [polypeptide binding]; other site
568704002519	conserved gate region; other site
568704002520	putative PBP binding loops; other site
568704002521	ABC-ATPase subunit interface; other site
568704002522	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstA; COG0581
568704002523	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568704002524	dimer interface [polypeptide binding]; other site
568704002525	conserved gate region; other site
568704002526	putative PBP binding loops; other site
568704002527	ABC-ATPase subunit interface; other site
568704002528	phosphate transporter ATP-binding protein; Provisional; Region: PRK14237
568704002529	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
568704002530	Walker A/P-loop; other site
568704002531	ATP binding site [chemical binding]; other site
568704002532	Q-loop/lid; other site
568704002533	ABC transporter signature motif; other site
568704002534	Walker B; other site
568704002535	D-loop; other site
568704002536	H-loop/switch region; other site
568704002537	phosphate ABC transporter ATP-binding protein; Provisional; Region: PRK14255
568704002538	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
568704002539	Walker A/P-loop; other site
568704002540	ATP binding site [chemical binding]; other site
568704002541	Q-loop/lid; other site
568704002542	ABC transporter signature motif; other site
568704002543	Walker B; other site
568704002544	D-loop; other site
568704002545	H-loop/switch region; other site
568704002546	phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135
568704002547	PhoU domain; Region: PhoU; pfam01895
568704002548	PhoU domain; Region: PhoU; pfam01895
568704002549	Uncharacterized conserved protein [Function unknown]; Region: COG3595
568704002550	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
568704002551	Membrane protein of unknown function; Region: DUF360; pfam04020
568704002552	HPr kinase/phosphorylase; Provisional; Region: PRK05428
568704002553	HPr Serine kinase N terminus; Region: Hpr_kinase_N; pfam02603
568704002554	HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent...; Region: HprK_C; cd01918
568704002555	Hpr binding site; other site
568704002556	active site
568704002557	homohexamer subunit interaction site [polypeptide binding]; other site
568704002558	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK12437
568704002559	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
568704002560	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
568704002561	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
568704002562	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
568704002563	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
568704002564	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
568704002565	phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150
568704002566	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
568704002567	active site
568704002568	substrate binding site [chemical binding]; other site
568704002569	metal binding site [ion binding]; metal-binding site
568704002570	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
568704002571	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568704002572	active site
568704002573	phosphorylation site [posttranslational modification]
568704002574	intermolecular recognition site; other site
568704002575	dimerization interface [polypeptide binding]; other site
568704002576	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
568704002577	DNA binding site [nucleotide binding]
568704002578	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
568704002579	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
568704002580	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568704002581	Mg2+ binding site [ion binding]; other site
568704002582	G-X-G motif; other site
568704002583	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
568704002584	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
568704002585	Walker A/P-loop; other site
568704002586	ATP binding site [chemical binding]; other site
568704002587	Q-loop/lid; other site
568704002588	ABC transporter signature motif; other site
568704002589	Walker B; other site
568704002590	D-loop; other site
568704002591	H-loop/switch region; other site
568704002592	FtsX-like permease family; Region: FtsX; pfam02687
568704002593	FtsX-like permease family; Region: FtsX; pfam02687
568704002594	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
568704002595	FtsX-like permease family; Region: FtsX; pfam02687
568704002596	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
568704002597	Zn2+ binding site [ion binding]; other site
568704002598	Mg2+ binding site [ion binding]; other site
568704002599	excinuclease ABC subunit B; Provisional; Region: PRK05298
568704002600	Myosin and Kinesin motor domain. These ATPases belong to the P-loop NTPase family and provide the driving force in myosin and kinesin mediated processes; Region: Motor_domain; cl00286
568704002601	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
568704002602	ATP-binding site [chemical binding]; other site
568704002603	ATP binding site [chemical binding]; other site
568704002604	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
568704002605	nucleotide binding region [chemical binding]; other site
568704002606	ATP-binding site [chemical binding]; other site
568704002607	Ultra-violet resistance protein B; Region: UvrB; pfam12344
568704002608	UvrB/uvrC motif; Region: UVR; pfam02151
568704002609	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
568704002610	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
568704002611	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
568704002612	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
568704002613	Short repeat of unknown function (DUF308); Region: DUF308; cl15828
568704002614	glmZ(sRNA)-inactivating NTPase; Provisional; Region: PRK05416
568704002615	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
568704002616	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
568704002617	phosphate binding site [ion binding]; other site
568704002618	putative substrate binding pocket [chemical binding]; other site
568704002619	dimer interface [polypeptide binding]; other site
568704002620	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1481
568704002621	Sporulation Regulator WhiA N terminal; Region: WhiA_N; pfam10298
568704002622	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
568704002623	MarR family; Region: MarR; pfam01047
568704002624	Clp protease; Region: CLP_protease; pfam00574
568704002625	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
568704002626	oligomer interface [polypeptide binding]; other site
568704002627	active site residues [active]
568704002628	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
568704002629	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
568704002630	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
568704002631	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
568704002632	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
568704002633	Phosphoglycerate kinase; Region: PGK; pfam00162
568704002634	substrate binding site [chemical binding]; other site
568704002635	hinge regions; other site
568704002636	ADP binding site [chemical binding]; other site
568704002637	catalytic site [active]
568704002638	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
568704002639	triosephosphate isomerase; Provisional; Region: PRK14567
568704002640	substrate binding site [chemical binding]; other site
568704002641	dimer interface [polypeptide binding]; other site
568704002642	catalytic triad [active]
568704002643	enolase; Provisional; Region: eno; PRK00077
568704002644	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
568704002645	dimer interface [polypeptide binding]; other site
568704002646	metal binding site [ion binding]; metal-binding site
568704002647	substrate binding pocket [chemical binding]; other site
568704002648	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
568704002649	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
568704002650	Cl- selectivity filter; other site
568704002651	Cl- binding residues [ion binding]; other site
568704002652	pore gating glutamate residue; other site
568704002653	dimer interface [polypeptide binding]; other site
568704002654	H+/Cl- coupling transport residue; other site
568704002655	TrkA-C domain; Region: TrkA_C; pfam02080
568704002656	preprotein translocase subunit SecG; Reviewed; Region: secG; PRK06870
568704002657	Esterase/lipase [General function prediction only]; Region: COG1647
568704002658	Esterase/lipase [General function prediction only]; Region: COG1647
568704002659	Esterase/lipase [General function prediction only]; Region: COG1647
568704002660	ribonuclease R; Region: RNase_R; TIGR02063
568704002661	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
568704002662	RNB domain; Region: RNB; pfam00773
568704002663	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
568704002664	RNA binding site [nucleotide binding]; other site
568704002665	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
568704002666	SmpB-tmRNA interface; other site
568704002667	Transposase; Region: DEDD_Tnp_IS110; pfam01548
568704002668	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
568704002669	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
568704002670	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
568704002671	homodimer interface [polypeptide binding]; other site
568704002672	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
568704002673	active site
568704002674	homodimer interface [polypeptide binding]; other site
568704002675	catalytic site [active]
568704002676	maltose phosphorylase; Provisional; Region: PRK13807
568704002677	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
568704002678	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
568704002679	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
568704002680	beta-phosphoglucomutase; Region: bPGM; TIGR01990
568704002681	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
568704002682	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568704002683	motif II; other site
568704002684	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568704002685	sequence-specific DNA binding site [nucleotide binding]; other site
568704002686	salt bridge; other site
568704002687	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
568704002688	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
568704002689	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
568704002690	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
568704002691	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
568704002692	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
568704002693	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568704002694	dimer interface [polypeptide binding]; other site
568704002695	conserved gate region; other site
568704002696	putative PBP binding loops; other site
568704002697	ABC-ATPase subunit interface; other site
568704002698	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568704002699	dimer interface [polypeptide binding]; other site
568704002700	conserved gate region; other site
568704002701	putative PBP binding loops; other site
568704002702	ABC-ATPase subunit interface; other site
568704002703	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
568704002704	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704002705	Walker A/P-loop; other site
568704002706	ATP binding site [chemical binding]; other site
568704002707	Q-loop/lid; other site
568704002708	ABC transporter signature motif; other site
568704002709	Walker B; other site
568704002710	D-loop; other site
568704002711	H-loop/switch region; other site
568704002712	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568704002713	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
568704002714	Coenzyme A binding pocket [chemical binding]; other site
568704002715	Tubby C 2; Region: Tub_2; cl02043
568704002716	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568704002717	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
568704002718	active site
568704002719	motif I; other site
568704002720	motif II; other site
568704002721	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
568704002722	ligand binding site [chemical binding]; other site
568704002723	active site
568704002724	UGI interface [polypeptide binding]; other site
568704002725	catalytic site [active]
568704002726	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
568704002727	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
568704002728	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4152
568704002729	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704002730	Walker A/P-loop; other site
568704002731	ATP binding site [chemical binding]; other site
568704002732	Q-loop/lid; other site
568704002733	ABC transporter signature motif; other site
568704002734	Walker B; other site
568704002735	D-loop; other site
568704002736	H-loop/switch region; other site
568704002737	Domain of unknown function (DUF4162); Region: DUF4162; pfam13732
568704002738	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
568704002739	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
568704002740	an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III; Region: DNA_pol_III_epsilon_like; cd06130
568704002741	active site
568704002742	catalytic site [active]
568704002743	substrate binding site [chemical binding]; other site
568704002744	Human Ape1-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Ape1-like_AP-endo; cd09087
568704002745	active site
568704002746	putative catalytic site [active]
568704002747	DNA binding site [nucleotide binding]
568704002748	putative phosphate binding site [ion binding]; other site
568704002749	metal binding site A [ion binding]; metal-binding site
568704002750	AP binding site [nucleotide binding]; other site
568704002751	metal binding site B [ion binding]; metal-binding site
568704002752	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
568704002753	FAD binding domain; Region: FAD_binding_4; pfam01565
568704002754	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
568704002755	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
568704002756	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
568704002757	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568704002758	non-specific DNA binding site [nucleotide binding]; other site
568704002759	salt bridge; other site
568704002760	sequence-specific DNA binding site [nucleotide binding]; other site
568704002761	Cupin domain; Region: Cupin_2; pfam07883
568704002762	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
568704002763	ATP-binding cassette domain of the polyamine transporter; Region: ABC_PotA_N; cd03300
568704002764	Walker A/P-loop; other site
568704002765	ATP binding site [chemical binding]; other site
568704002766	Q-loop/lid; other site
568704002767	ABC transporter signature motif; other site
568704002768	Walker B; other site
568704002769	D-loop; other site
568704002770	H-loop/switch region; other site
568704002771	TOBE domain; Region: TOBE_2; pfam08402
568704002772	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
568704002773	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568704002774	dimer interface [polypeptide binding]; other site
568704002775	conserved gate region; other site
568704002776	putative PBP binding loops; other site
568704002777	ABC-ATPase subunit interface; other site
568704002778	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
568704002779	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568704002780	dimer interface [polypeptide binding]; other site
568704002781	conserved gate region; other site
568704002782	putative PBP binding loops; other site
568704002783	ABC-ATPase subunit interface; other site
568704002784	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
568704002785	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
568704002786	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
568704002787	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
568704002788	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
568704002789	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
568704002790	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568704002791	motif II; other site
568704002792	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
568704002793	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
568704002794	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
568704002795	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
568704002796	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
568704002797	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
568704002798	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
568704002799	ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system; Region: PQQ_ABC_ATP; TIGR03864
568704002800	Walker A/P-loop; other site
568704002801	ATP binding site [chemical binding]; other site
568704002802	Q-loop/lid; other site
568704002803	ABC transporter signature motif; other site
568704002804	Walker B; other site
568704002805	D-loop; other site
568704002806	H-loop/switch region; other site
568704002807	Uncharacterized conserved protein [Function unknown]; Region: COG1624
568704002808	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
568704002809	YbbR-like protein; Region: YbbR; pfam07949
568704002810	YbbR-like protein; Region: YbbR; pfam07949
568704002811	YbbR-like protein; Region: YbbR; pfam07949
568704002812	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14316
568704002813	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
568704002814	active site
568704002815	substrate binding site [chemical binding]; other site
568704002816	metal binding site [ion binding]; metal-binding site
568704002817	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
568704002818	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
568704002819	glutaminase active site [active]
568704002820	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
568704002821	dimer interface [polypeptide binding]; other site
568704002822	active site
568704002823	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
568704002824	dimer interface [polypeptide binding]; other site
568704002825	active site
568704002826	oligoendopeptidase, pepF/M3 family; Region: M3_fam_3; TIGR02290
568704002827	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_2; cd09607
568704002828	active site
568704002829	Zn binding site [ion binding]; other site
568704002830	Predicted integral membrane protein [Function unknown]; Region: COG5652
568704002831	hypothetical protein; Validated; Region: PRK00110
568704002832	Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459
568704002833	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
568704002834	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
568704002835	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827
568704002836	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568704002837	S-adenosylmethionine binding site [chemical binding]; other site
568704002838	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
568704002839	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
568704002840	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cl17185
568704002841	putative acyl-acceptor binding pocket; other site
568704002842	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
568704002843	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
568704002844	active site
568704002845	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
568704002846	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
568704002847	Ligand binding site; other site
568704002848	metal-binding site
568704002849	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
568704002850	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
568704002851	putative acyl-acceptor binding pocket; other site
568704002852	Alpha-galactosidase [Carbohydrate transport and metabolism]; Region: GalA; COG3345
568704002853	Melibiase; Region: Melibiase; pfam02065
568704002854	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
568704002855	Int/Topo IB signature motif; other site
568704002856	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
568704002857	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568704002858	non-specific DNA binding site [nucleotide binding]; other site
568704002859	salt bridge; other site
568704002860	sequence-specific DNA binding site [nucleotide binding]; other site
568704002861	Helix-turn-helix domain; Region: HTH_17; pfam12728
568704002862	Prim_Pol: Primase-polymerase (primpol) domain of the type found in bifunctional replicases from archaeal plasmids, including ORF904 protein of the crenarchaeal plasmid pRN1 from Sulfolobus islandicus (pRN1 primpol). These primpol domains belong to the...; Region: Prim_Pol; cd04859
568704002863	polymerase nucleotide-binding site; other site
568704002864	DNA-binding residues [nucleotide binding]; DNA binding site
568704002865	nucleotide binding site [chemical binding]; other site
568704002866	primase nucleotide-binding site [nucleotide binding]; other site
568704002867	Primase C terminal 1 (PriCT-1); Region: PriCT_1; smart00942
568704002868	Virulence-associated protein E; Region: VirE; pfam05272
568704002869	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
568704002870	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
568704002871	active site
568704002872	Phage terminase, small subunit; Region: Terminase_4; pfam05119
568704002873	Phage Terminase; Region: Terminase_1; pfam03354
568704002874	Phage portal protein; Region: Phage_portal; pfam04860
568704002875	Phage-related protein [Function unknown]; Region: COG4695; cl01923
568704002876	Caudovirus prohead protease; Region: Peptidase_U35; pfam04586
568704002877	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
568704002878	Phage capsid family; Region: Phage_capsid; pfam05065
568704002879	Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; Region: gp6; cd08054
568704002880	oligomerization interface [polypeptide binding]; other site
568704002881	Predicted membrane protein [Function unknown]; Region: COG2261
568704002882	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
568704002883	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
568704002884	SdpI/YhfL protein family; Region: SdpI; pfam13630
568704002885	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
568704002886	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568704002887	active site
568704002888	phosphorylation site [posttranslational modification]
568704002889	intermolecular recognition site; other site
568704002890	dimerization interface [polypeptide binding]; other site
568704002891	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
568704002892	DNA binding site [nucleotide binding]
568704002893	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
568704002894	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
568704002895	dimerization interface [polypeptide binding]; other site
568704002896	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
568704002897	dimer interface [polypeptide binding]; other site
568704002898	phosphorylation site [posttranslational modification]
568704002899	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568704002900	ATP binding site [chemical binding]; other site
568704002901	Mg2+ binding site [ion binding]; other site
568704002902	G-X-G motif; other site
568704002903	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
568704002904	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568704002905	Coenzyme A binding pocket [chemical binding]; other site
568704002906	hypothetical protein; Provisional; Region: PRK04435
568704002907	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cl17393
568704002908	DNA-binding interface [nucleotide binding]; DNA binding site
568704002909	C-terminal ACT domain of a small (; 147 a.a.) putative phenylalanine biosynthetic pathway protein described in Bacillus subtilis (BS) PheB (PheB-BS) and related domains; Region: ACT_PheB-BS; cd04888
568704002910	DNA polymerase IV; Reviewed; Region: PRK03103
568704002911	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
568704002912	active site
568704002913	DNA binding site [nucleotide binding]
568704002914	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
568704002915	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
568704002916	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
568704002917	active site
568704002918	catalytic triad [active]
568704002919	oxyanion hole [active]
568704002920	Bacterial protein of unknown function (DUF898); Region: DUF898; cl01738
568704002921	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
568704002922	Part of AAA domain; Region: AAA_19; pfam13245
568704002923	Family description; Region: UvrD_C_2; pfam13538
568704002924	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
568704002925	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
568704002926	nucleotide binding pocket [chemical binding]; other site
568704002927	K-X-D-G motif; other site
568704002928	catalytic site [active]
568704002929	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
568704002930	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
568704002931	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
568704002932	Dimer interface [polypeptide binding]; other site
568704002933	BRCT sequence motif; other site
568704002934	N-terminal repeat domain of CamS sex pheromone cAM373 precursor; Region: CamS_repeat_1; cd13441
568704002935	putative dimer interface [polypeptide binding]; other site
568704002936	CamS sex pheromone cAM373 precursor; Region: CamS; pfam07537
568704002937	C-terminal repeat domain of CamS sex pheromone cAM373 precursor; Region: CamS_repeat_2; cd13440
568704002938	putative dimer interface [polypeptide binding]; other site
568704002939	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
568704002940	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
568704002941	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
568704002942	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
568704002943	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
568704002944	GatB domain; Region: GatB_Yqey; smart00845
568704002945	putative lipid kinase; Reviewed; Region: PRK13055
568704002946	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
568704002947	TRAM domain; Region: TRAM; pfam01938
568704002948	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
568704002949	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568704002950	S-adenosylmethionine binding site [chemical binding]; other site
568704002951	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704002952	Major Facilitator Superfamily; Region: MFS_1; pfam07690
568704002953	putative substrate translocation pore; other site
568704002954	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568704002955	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
568704002956	active site
568704002957	motif I; other site
568704002958	motif II; other site
568704002959	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
568704002960	polyphosphate:nucleotide phosphotransferase, PPK2 family; Region: PPK2_rel_1; TIGR03709
568704002961	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
568704002962	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
568704002963	active site
568704002964	Zn binding site [ion binding]; other site
568704002965	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
568704002966	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568704002967	Coenzyme A binding pocket [chemical binding]; other site
568704002968	EDD domain protein, DegV family; Region: DegV; TIGR00762
568704002969	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
568704002970	HflC protein; Region: hflC; TIGR01932
568704002971	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
568704002972	Uncharacterized bacterial muramidase containing a glycosyl hydrolase family 25 (GH25) catalytic domain. Endo-N-acetylmuramidases are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis...; Region: GH25_muramidase_2; cd06419
568704002973	active site
568704002974	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
568704002975	Protein of unknown function (DUF1093); Region: DUF1093; cl02185
568704002976	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
568704002977	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
568704002978	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
568704002979	DEAD-like helicases superfamily; Region: DEXDc; smart00487
568704002980	ATP binding site [chemical binding]; other site
568704002981	putative Mg++ binding site [ion binding]; other site
568704002982	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
568704002983	nucleotide binding region [chemical binding]; other site
568704002984	ATP-binding site [chemical binding]; other site
568704002985	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cl00166
568704002986	active site
568704002987	methionine cluster; other site
568704002988	phosphorylation site [posttranslational modification]
568704002989	metal binding site [ion binding]; metal-binding site
568704002990	Domain of unknown function (DUF3284); Region: DUF3284; pfam11687
568704002991	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
568704002992	active site
568704002993	ATP-dependent DNA helicase RecQ; Region: recQ; TIGR01389
568704002994	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
568704002995	ATP binding site [chemical binding]; other site
568704002996	putative Mg++ binding site [ion binding]; other site
568704002997	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
568704002998	nucleotide binding region [chemical binding]; other site
568704002999	ATP-binding site [chemical binding]; other site
568704003000	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
568704003001	HRDC domain; Region: HRDC; pfam00570
568704003002	Thermophilic metalloprotease (M29); Region: Peptidase_M29; pfam02073
568704003003	Leucyl aminopeptidase (aminopeptidase T) [Amino acid transport and metabolism]; Region: AmpS; COG2309
568704003004	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
568704003005	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
568704003006	WHG domain; Region: WHG; pfam13305
568704003007	Uncharacterized protein conserved in bacteria (DUF2252); Region: DUF2252; pfam10009
568704003008	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4320
568704003009	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
568704003010	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
568704003011	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
568704003012	active site
568704003013	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
568704003014	active site
568704003015	Protein of unknown function (DUF2922); Region: DUF2922; pfam11148
568704003016	Citrate synthase (CS), citryl-CoA lyase (CCL), the C-terminal portion of the single-subunit type ATP-citrate lyase (ACL) and the C-terminal portion of the large subunit of the two-subunit type ACL. CS catalyzes the condensation of acetyl coenzyme A; Region: CS_ACL-C_CCL; cl00416
568704003017	phosphomevalonate kinase, ERG8-type, Gram-positive branch; Region: Pmev_kin_Gr_pos; TIGR01220
568704003018	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
568704003019	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
568704003020	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
568704003021	active site
568704003022	tetramer interface; other site
568704003023	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
568704003024	active site
568704003025	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
568704003026	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
568704003027	active site
568704003028	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
568704003029	beta-1,6-galactofuranosyltransferase; Provisional; Region: PRK09814
568704003030	SecA DEAD-like domain; Region: SecA_DEAD; smart00957
568704003031	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
568704003032	ATP binding site [chemical binding]; other site
568704003033	SecA preprotein cross-linking domain; Region: SecA_PP_bind; cl03078
568704003034	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
568704003035	beta-galactosidase; Region: BGL; TIGR03356
568704003036	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
568704003037	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
568704003038	active site turn [active]
568704003039	phosphorylation site [posttranslational modification]
568704003040	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
568704003041	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
568704003042	HPr interaction site; other site
568704003043	glycerol kinase (GK) interaction site [polypeptide binding]; other site
568704003044	active site
568704003045	phosphorylation site [posttranslational modification]
568704003046	Bacterial membrane protein YfhO; Region: YfhO; pfam09586
568704003047	Bacterial membrane protein YfhO; Region: YfhO; pfam09586
568704003048	Fic/DOC family; Region: Fic; cl00960
568704003049	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
568704003050	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
568704003051	Ligand binding site; other site
568704003052	Putative Catalytic site; other site
568704003053	DXD motif; other site
568704003054	Predicted membrane protein [Function unknown]; Region: COG4129
568704003055	Bacterial protein of unknown function (DUF939); Region: DUF939; pfam06081
568704003056	DUF939 C-terminal domain; Region: DUF939_C; pfam11728
568704003057	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
568704003058	DNA-binding site [nucleotide binding]; DNA binding site
568704003059	RNA-binding motif; other site
568704003060	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
568704003061	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
568704003062	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
568704003063	active site
568704003064	xanthine permease; Region: pbuX; TIGR03173
568704003065	phosphoribosylaminoimidazole carboxylase, PurK protein; Region: purK; TIGR01161
568704003066	ATP-grasp domain; Region: ATP-grasp_4; cl17255
568704003067	adenylosuccinate lyase; Provisional; Region: PRK07492
568704003068	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
568704003069	tetramer interface [polypeptide binding]; other site
568704003070	active site
568704003071	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
568704003072	Sulfatase; Region: Sulfatase; pfam00884
568704003073	Glycopeptide antibiotics resistance protein [Defense mechanisms]; Region: VanZ; COG4767
568704003074	Sugar transport protein; Region: Sugar_transport; pfam06800
568704003075	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14097
568704003076	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
568704003077	active site
568704003078	dimer interface [polypeptide binding]; other site
568704003079	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
568704003080	dimer interface [polypeptide binding]; other site
568704003081	active site
568704003082	Uncharacterized conserved protein [Function unknown]; Region: COG1359
568704003083	DNA/RNA non-specific endonuclease; Region: Endonuclea_NS_2; pfam13930
568704003084	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
568704003085	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
568704003086	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
568704003087	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
568704003088	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
568704003089	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
568704003090	nucleoside/Zn binding site; other site
568704003091	dimer interface [polypeptide binding]; other site
568704003092	catalytic motif [active]
568704003093	Major Facilitator Superfamily; Region: MFS_1; pfam07690
568704003094	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704003095	Peptidase family C69; Region: Peptidase_C69; pfam03577
568704003096	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
568704003097	catalytic core [active]
568704003098	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
568704003099	catalytic core [active]
568704003100	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
568704003101	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
568704003102	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
568704003103	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
568704003104	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704003105	Walker A/P-loop; other site
568704003106	ATP binding site [chemical binding]; other site
568704003107	Q-loop/lid; other site
568704003108	ABC transporter signature motif; other site
568704003109	Walker B; other site
568704003110	D-loop; other site
568704003111	H-loop/switch region; other site
568704003112	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
568704003113	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
568704003114	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
568704003115	Walker A/P-loop; other site
568704003116	ATP binding site [chemical binding]; other site
568704003117	Q-loop/lid; other site
568704003118	ABC transporter signature motif; other site
568704003119	Walker B; other site
568704003120	D-loop; other site
568704003121	H-loop/switch region; other site
568704003122	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
568704003123	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
568704003124	Predicted ring-cleavage extradiol dioxygenase [General function prediction only]; Region: COG2514
568704003125	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
568704003126	active site
568704003127	metal binding site [ion binding]; metal-binding site
568704003128	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
568704003129	active site
568704003130	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
568704003131	Beta-lactamase; Region: Beta-lactamase; pfam00144
568704003132	UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurE; COG0769
568704003133	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
568704003134	Domain of unknown function (DUF1727); Region: DUF1727; pfam08353
568704003135	thymidine kinase; Provisional; Region: PRK04296
568704003136	peptide chain release factor 1; Validated; Region: prfA; PRK00591
568704003137	This domain is found in peptide chain release factors; Region: PCRF; smart00937
568704003138	RF-1 domain; Region: RF-1; pfam00472
568704003139	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
568704003140	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568704003141	S-adenosylmethionine binding site [chemical binding]; other site
568704003142	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
568704003143	Putative GTP-binding controlling metal-binding; Region: SUA5; pfam03481
568704003144	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
568704003145	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
568704003146	dimer interface [polypeptide binding]; other site
568704003147	active site
568704003148	glycine-pyridoxal phosphate binding site [chemical binding]; other site
568704003149	folate binding site [chemical binding]; other site
568704003150	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
568704003151	active site
568704003152	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
568704003153	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
568704003154	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
568704003155	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
568704003156	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
568704003157	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
568704003158	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
568704003159	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
568704003160	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
568704003161	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
568704003162	beta subunit interaction interface [polypeptide binding]; other site
568704003163	Walker A motif; other site
568704003164	ATP binding site [chemical binding]; other site
568704003165	Walker B motif; other site
568704003166	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
568704003167	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
568704003168	core domain interface [polypeptide binding]; other site
568704003169	delta subunit interface [polypeptide binding]; other site
568704003170	epsilon subunit interface [polypeptide binding]; other site
568704003171	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
568704003172	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
568704003173	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
568704003174	alpha subunit interaction interface [polypeptide binding]; other site
568704003175	Walker A motif; other site
568704003176	ATP binding site [chemical binding]; other site
568704003177	Walker B motif; other site
568704003178	inhibitor binding site; inhibition site
568704003179	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
568704003180	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
568704003181	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
568704003182	gamma subunit interface [polypeptide binding]; other site
568704003183	epsilon subunit interface [polypeptide binding]; other site
568704003184	LBP interface [polypeptide binding]; other site
568704003185	Protein of unknown function (DUF1146); Region: DUF1146; cl11486
568704003186	rod shape-determining protein MreB; Provisional; Region: PRK13930
568704003187	MreB and similar proteins; Region: MreB_like; cd10225
568704003188	nucleotide binding site [chemical binding]; other site
568704003189	Mg binding site [ion binding]; other site
568704003190	putative protofilament interaction site [polypeptide binding]; other site
568704003191	RodZ interaction site [polypeptide binding]; other site
568704003192	DNA-directed RNA polymerase subunit beta; Region: EpuA; pfam11772
568704003193	Haemolytic domain; Region: Haemolytic; cl00506
568704003194	Protein of unknown function (DUF2969); Region: DUF2969; pfam11184
568704003195	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
568704003196	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
568704003197	lipoyl attachment site [posttranslational modification]; other site
568704003198	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK08588
568704003199	Peptidase M20 acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase (ArgE/DapE)-like; Region: M20_ArgE_DapE_like; cd08659
568704003200	metal binding site [ion binding]; metal-binding site
568704003201	dimer interface [polypeptide binding]; other site
568704003202	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
568704003203	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
568704003204	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
568704003205	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
568704003206	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
568704003207	Walker A/P-loop; other site
568704003208	ATP binding site [chemical binding]; other site
568704003209	Q-loop/lid; other site
568704003210	ABC transporter signature motif; other site
568704003211	Walker B; other site
568704003212	D-loop; other site
568704003213	H-loop/switch region; other site
568704003214	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
568704003215	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568704003216	dimer interface [polypeptide binding]; other site
568704003217	conserved gate region; other site
568704003218	ABC-ATPase subunit interface; other site
568704003219	Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones]; Region: sufC; COG0396
568704003220	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
568704003221	Walker A/P-loop; other site
568704003222	ATP binding site [chemical binding]; other site
568704003223	Q-loop/lid; other site
568704003224	ABC transporter signature motif; other site
568704003225	Walker B; other site
568704003226	D-loop; other site
568704003227	H-loop/switch region; other site
568704003228	Uncharacterized protein family (UPF0051); Region: UPF0051; pfam01458
568704003229	FeS assembly protein SufD; Region: sufD; TIGR01981
568704003230	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
568704003231	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
568704003232	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
568704003233	catalytic residue [active]
568704003234	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
568704003235	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
568704003236	trimerization site [polypeptide binding]; other site
568704003237	active site
568704003238	FeS assembly protein SufB; Region: sufB; TIGR01980
568704003239	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814; cl03223
568704003240	Protein of unknown function (DUF1694); Region: DUF1694; pfam07997
568704003241	Protein of unknown function (DUF2785); Region: DUF2785; pfam10978
568704003242	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
568704003243	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568704003244	non-specific DNA binding site [nucleotide binding]; other site
568704003245	salt bridge; other site
568704003246	sequence-specific DNA binding site [nucleotide binding]; other site
568704003247	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
568704003248	Ligand Binding Site [chemical binding]; other site
568704003249	recombination factor protein RarA; Reviewed; Region: PRK13342
568704003250	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568704003251	Walker A motif; other site
568704003252	ATP binding site [chemical binding]; other site
568704003253	Walker B motif; other site
568704003254	arginine finger; other site
568704003255	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
568704003256	bifunctional glutamate--cysteine ligase/glutathione synthetase; Provisional; Region: PRK02471
568704003257	Protein of unknown function (DUF1694); Region: DUF1694; pfam07997
568704003258	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4493
568704003259	Protein of unknown function (DUF1054); Region: DUF1054; pfam06335
568704003260	L-serine dehydratase, iron-sulfur-dependent, beta subunit; Region: sda_beta; TIGR00719
568704003261	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
568704003262	C-terminal ACT domain of the L-serine dehydratase (LSD), iron-sulfur-dependent, beta subunit; Region: ACT_LSD; cd04903
568704003263	putative L-serine binding site [chemical binding]; other site
568704003264	Serine dehydratase alpha chain; Region: SDH_alpha; cl12120
568704003265	L-serine deaminase [Amino acid transport and metabolism]; Region: SdaA; COG1760
568704003266	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
568704003267	bifunctional RNase H/acid phosphatase; Provisional; Region: PRK07238
568704003268	catalytic core [active]
568704003269	Enterocin A Immunity; Region: EntA_Immun; pfam08951
568704003270	methionine sulfoxide reductase A; Provisional; Region: PRK14054
568704003271	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
568704003272	NAD(P) binding site [chemical binding]; other site
568704003273	active site
568704003274	Nicotinamide mononucleotide transporter; Region: NMN_transporter; pfam04973
568704003275	Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428
568704003276	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
568704003277	active site
568704003278	hypothetical protein; Provisional; Region: PRK07329
568704003279	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
568704003280	active site
568704003281	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
568704003282	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
568704003283	peptide binding site [polypeptide binding]; other site
568704003284	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
568704003285	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
568704003286	dimer interface [polypeptide binding]; other site
568704003287	phosphorylation site [posttranslational modification]
568704003288	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568704003289	ATP binding site [chemical binding]; other site
568704003290	Mg2+ binding site [ion binding]; other site
568704003291	G-X-G motif; other site
568704003292	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
568704003293	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568704003294	active site
568704003295	phosphorylation site [posttranslational modification]
568704003296	intermolecular recognition site; other site
568704003297	dimerization interface [polypeptide binding]; other site
568704003298	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
568704003299	DNA binding site [nucleotide binding]
568704003300	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
568704003301	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704003302	Walker A/P-loop; other site
568704003303	ATP binding site [chemical binding]; other site
568704003304	Q-loop/lid; other site
568704003305	ABC transporter signature motif; other site
568704003306	Walker B; other site
568704003307	D-loop; other site
568704003308	H-loop/switch region; other site
568704003309	Transcriptional regulator [Transcription]; Region: LysR; COG0583
568704003310	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568704003311	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
568704003312	dimerization interface [polypeptide binding]; other site
568704003313	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
568704003314	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
568704003315	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568704003316	Coenzyme A binding pocket [chemical binding]; other site
568704003317	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568704003318	Coenzyme A binding pocket [chemical binding]; other site
568704003319	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568704003320	Coenzyme A binding pocket [chemical binding]; other site
568704003321	EDD domain protein, DegV family; Region: DegV; TIGR00762
568704003322	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
568704003323	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
568704003324	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568704003325	active site
568704003326	phosphorylation site [posttranslational modification]
568704003327	intermolecular recognition site; other site
568704003328	dimerization interface [polypeptide binding]; other site
568704003329	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
568704003330	DNA binding residues [nucleotide binding]
568704003331	dimerization interface [polypeptide binding]; other site
568704003332	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
568704003333	Histidine kinase; Region: HisKA_3; pfam07730
568704003334	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568704003335	ATP binding site [chemical binding]; other site
568704003336	Mg2+ binding site [ion binding]; other site
568704003337	G-X-G motif; other site
568704003338	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
568704003339	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
568704003340	Walker A/P-loop; other site
568704003341	ATP binding site [chemical binding]; other site
568704003342	Q-loop/lid; other site
568704003343	ABC transporter signature motif; other site
568704003344	Walker B; other site
568704003345	D-loop; other site
568704003346	H-loop/switch region; other site
568704003347	Protein of unknown function C-terminus (DUF2399); Region: DUF2399; pfam09664
568704003348	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
568704003349	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
568704003350	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
568704003351	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
568704003352	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
568704003353	RNA binding site [nucleotide binding]; other site
568704003354	Predicted glutamine amidotransferases [General function prediction only]; Region: COG2071
568704003355	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
568704003356	catalytic triad [active]
568704003357	amino acid transporter; Region: 2A0306; TIGR00909
568704003358	amino acid transporter; Region: 2A0306; TIGR00909
568704003359	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
568704003360	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
568704003361	cofactor binding site; other site
568704003362	DNA binding site [nucleotide binding]
568704003363	substrate interaction site [chemical binding]; other site
568704003364	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
568704003365	Domain of unknown function (DUF1998); Region: DUF1998; pfam09369
568704003366	DEAD/DEAH box helicase; Region: DEAD; pfam00270
568704003367	Helicase conserved C-terminal domain; Region: Helicase_C; pfam00271
568704003368	ATP-binding site [chemical binding]; other site
568704003369	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
568704003370	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
568704003371	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
568704003372	RNA binding surface [nucleotide binding]; other site
568704003373	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
568704003374	GAF domain; Region: GAF_2; pfam13185
568704003375	septation ring formation regulator EzrA; Provisional; Region: PRK04778
568704003376	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
568704003377	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
568704003378	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
568704003379	catalytic residue [active]
568704003380	thiamine biosynthesis protein ThiI; Provisional; Region: PRK01565
568704003381	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
568704003382	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
568704003383	Ligand Binding Site [chemical binding]; other site
568704003384	redox-sensing transcriptional repressor Rex; Provisional; Region: PRK05472
568704003385	Putative DNA-binding protein N-terminus; Region: Put_DNA-bind_N; pfam06971
568704003386	CoA binding domain; Region: CoA_binding; pfam02629
568704003387	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
568704003388	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
568704003389	active site
568704003390	HIGH motif; other site
568704003391	nucleotide binding site [chemical binding]; other site
568704003392	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
568704003393	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
568704003394	active site
568704003395	KMSKS motif; other site
568704003396	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
568704003397	tRNA binding surface [nucleotide binding]; other site
568704003398	anticodon binding site; other site
568704003399	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
568704003400	folylpolyglutamate synthase/dihydrofolate synthase; Region: folC; TIGR01499
568704003401	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
568704003402	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
568704003403	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568704003404	motif II; other site
568704003405	hypothetical protein; Reviewed; Region: PRK00024
568704003406	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
568704003407	MPN+ (JAMM) motif; other site
568704003408	Zinc-binding site [ion binding]; other site
568704003409	rod shape-determining protein MreB; Provisional; Region: PRK13927
568704003410	MreB and similar proteins; Region: MreB_like; cd10225
568704003411	nucleotide binding site [chemical binding]; other site
568704003412	Mg binding site [ion binding]; other site
568704003413	putative protofilament interaction site [polypeptide binding]; other site
568704003414	RodZ interaction site [polypeptide binding]; other site
568704003415	rod shape-determining protein MreC; Provisional; Region: PRK13922
568704003416	Protein of unknown function (DUF904); Region: DUF904; pfam06005
568704003417	rod shape-determining protein MreC; Region: MreC; pfam04085
568704003418	rod shape-determining protein MreD; Region: shape_MreD; TIGR03426
568704003419	septum formation inhibitor; Reviewed; Region: minC; PRK00513
568704003420	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
568704003421	Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning]; Region: MinD; COG2894
568704003422	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
568704003423	Switch I; other site
568704003424	Switch II; other site
568704003425	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568704003426	dimer interface [polypeptide binding]; other site
568704003427	conserved gate region; other site
568704003428	putative PBP binding loops; other site
568704003429	ABC-ATPase subunit interface; other site
568704003430	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
568704003431	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704003432	Walker A/P-loop; other site
568704003433	ATP binding site [chemical binding]; other site
568704003434	Q-loop/lid; other site
568704003435	ABC transporter signature motif; other site
568704003436	Walker B; other site
568704003437	D-loop; other site
568704003438	H-loop/switch region; other site
568704003439	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
568704003440	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
568704003441	substrate binding pocket [chemical binding]; other site
568704003442	membrane-bound complex binding site; other site
568704003443	hinge residues; other site
568704003444	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
568704003445	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
568704003446	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
568704003447	putative active site [active]
568704003448	catalytic site [active]
568704003449	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
568704003450	putative active site [active]
568704003451	catalytic site [active]
568704003452	cell division protein MraZ; Reviewed; Region: PRK00326
568704003453	MraZ protein; Region: MraZ; pfam02381
568704003454	MraZ protein; Region: MraZ; pfam02381
568704003455	MraW methylase family; Region: Methyltransf_5; cl17771
568704003456	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
568704003457	MraW methylase family; Region: Methyltransf_5; cl17771
568704003458	Cell division protein FtsL; Region: FtsL; cl11433
568704003459	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
568704003460	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
568704003461	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
568704003462	PASTA domain of PBP2x-like proteins, first repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_1; cd06576
568704003463	PASTA domain of PBP2x-like proteins, second repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_2; cd06575
568704003464	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
568704003465	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
568704003466	Mg++ binding site [ion binding]; other site
568704003467	putative catalytic motif [active]
568704003468	putative substrate binding site [chemical binding]; other site
568704003469	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK02472
568704003470	Alanine dehydrogenase/PNT, C-terminal domain; Region: AlaDh_PNT_C; smart01002
568704003471	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
568704003472	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
568704003473	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
568704003474	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
568704003475	active site
568704003476	homodimer interface [polypeptide binding]; other site
568704003477	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
568704003478	Cell division protein FtsQ; Region: FtsQ; pfam03799
568704003479	Cell division ATPase FtsA [Cell division and chromosome partitioning]; Region: ftsA; COG0849
568704003480	Cell division protein FtsA; Region: FtsA; smart00842
568704003481	Cell division protein FtsA; Region: FtsA; pfam14450
568704003482	cell division protein FtsZ; Validated; Region: PRK09330
568704003483	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
568704003484	nucleotide binding site [chemical binding]; other site
568704003485	SulA interaction site; other site
568704003486	Protein of unknown function (DUF552); Region: DUF552; pfam04472
568704003487	YGGT family; Region: YGGT; pfam02325
568704003488	Uncharacterized conserved protein, contains S4-like domain [Function unknown]; Region: COG2302
568704003489	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
568704003490	RNA binding surface [nucleotide binding]; other site
568704003491	DivIVA protein; Region: DivIVA; pfam05103
568704003492	DivIVA domain; Region: DivI1A_domain; TIGR03544
568704003493	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
568704003494	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
568704003495	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
568704003496	active site
568704003497	HIGH motif; other site
568704003498	nucleotide binding site [chemical binding]; other site
568704003499	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
568704003500	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
568704003501	active site
568704003502	KMSKS motif; other site
568704003503	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
568704003504	tRNA binding surface [nucleotide binding]; other site
568704003505	anticodon binding site; other site
568704003506	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
568704003507	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
568704003508	DNA-binding site [nucleotide binding]; DNA binding site
568704003509	RNA-binding motif; other site
568704003510	PBP superfamily domain; Region: PBP_like_2; cl17296
568704003511	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
568704003512	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704003513	putative substrate translocation pore; other site
568704003514	nitrite extrusion protein (nitrite facilitator); Region: 2A0108; TIGR00886
568704003515	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704003516	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704003517	Toxic anion resistance protein (TelA); Region: TelA; pfam05816
568704003518	5-bromo-4-chloroindolyl phosphate hydrolysis protein; Region: Halogen_Hydrol; pfam10112
568704003519	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
568704003520	dimer interface [polypeptide binding]; other site
568704003521	ADP-ribose binding site [chemical binding]; other site
568704003522	active site
568704003523	nudix motif; other site
568704003524	metal binding site [ion binding]; metal-binding site
568704003525	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
568704003526	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
568704003527	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
568704003528	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
568704003529	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
568704003530	catalytic residue [active]
568704003531	Putative amino acid metabolism; Region: DUF1831; pfam08866
568704003532	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704003533	Excinuclease ATPase subunit [DNA replication, recombination, and repair]; Region: UvrA; COG0178
568704003534	Walker A/P-loop; other site
568704003535	ATP binding site [chemical binding]; other site
568704003536	Q-loop/lid; other site
568704003537	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704003538	ABC transporter signature motif; other site
568704003539	Walker B; other site
568704003540	D-loop; other site
568704003541	H-loop/switch region; other site
568704003542	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704003543	Walker A/P-loop; other site
568704003544	ATP binding site [chemical binding]; other site
568704003545	Q-loop/lid; other site
568704003546	ABC transporter signature motif; other site
568704003547	Walker B; other site
568704003548	D-loop; other site
568704003549	H-loop/switch region; other site
568704003550	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
568704003551	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
568704003552	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
568704003553	catalytic core [active]
568704003554	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
568704003555	TPR motif; other site
568704003556	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
568704003557	H3TH domains of structure-specific 5' nucleases (or flap endonuclease-1-like) involved in DNA replication, repair, and recombination; Region: H3TH_StructSpec-5'-nucleases; cl14815
568704003558	AAA domain; Region: AAA_30; pfam13604
568704003559	Family description; Region: UvrD_C_2; pfam13538
568704003560	Acetyltransferase (GNAT) domain; Region: Acetyltransf_9; pfam13527
568704003561	Sterol carrier protein domain; Region: SCP2_2; pfam13530
568704003562	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
568704003563	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
568704003564	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
568704003565	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
568704003566	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
568704003567	hypothetical protein; Provisional; Region: PRK13667
568704003568	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
568704003569	active site
568704003570	catalytic residues [active]
568704003571	metal binding site [ion binding]; metal-binding site
568704003572	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
568704003573	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_x; TIGR03181
568704003574	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
568704003575	TPP-binding site [chemical binding]; other site
568704003576	tetramer interface [polypeptide binding]; other site
568704003577	heterodimer interface [polypeptide binding]; other site
568704003578	phosphorylation loop region [posttranslational modification]
568704003579	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
568704003580	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
568704003581	alpha subunit interface [polypeptide binding]; other site
568704003582	TPP binding site [chemical binding]; other site
568704003583	heterodimer interface [polypeptide binding]; other site
568704003584	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
568704003585	dihydrolipoamide acetyltransferase; Reviewed; Region: PRK11855
568704003586	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
568704003587	E3 interaction surface; other site
568704003588	lipoyl attachment site [posttranslational modification]; other site
568704003589	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
568704003590	E3 interaction surface; other site
568704003591	lipoyl attachment site [posttranslational modification]; other site
568704003592	e3 binding domain; Region: E3_binding; pfam02817
568704003593	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
568704003594	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06416
568704003595	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
568704003596	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
568704003597	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
568704003598	NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195
568704003599	substrate binding site [chemical binding]; other site
568704003600	Uncharacterized protein family (UPF0223); Region: UPF0223; pfam05256
568704003601	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
568704003602	Inositol-monophosphatase-like domains. This family of phosphatases is dependent on bivalent metal ions such as Mg++, and many members are inhibited by Li+ (which is thought to displace a bivalent ion in the active site). Substrates include fructose-1; Region: IMPase_like; cd01637
568704003603	active site
568704003604	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
568704003605	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
568704003606	G1 box; other site
568704003607	putative GEF interaction site [polypeptide binding]; other site
568704003608	GTP/Mg2+ binding site [chemical binding]; other site
568704003609	Switch I region; other site
568704003610	G2 box; other site
568704003611	G3 box; other site
568704003612	Switch II region; other site
568704003613	G4 box; other site
568704003614	G5 box; other site
568704003615	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
568704003616	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
568704003617	cell division protein FtsW; Region: ftsW; TIGR02614
568704003618	pyruvate carboxylase; Reviewed; Region: PRK12999
568704003619	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
568704003620	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
568704003621	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
568704003622	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
568704003623	active site
568704003624	catalytic residues [active]
568704003625	metal binding site [ion binding]; metal-binding site
568704003626	homodimer binding site [polypeptide binding]; other site
568704003627	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
568704003628	carboxyltransferase (CT) interaction site; other site
568704003629	biotinylation site [posttranslational modification]; other site
568704003630	Uncharacterized protein conserved in bacteria (DUF2129); Region: DUF2129; pfam09902
568704003631	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
568704003632	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568704003633	S-adenosylmethionine binding site [chemical binding]; other site
568704003634	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
568704003635	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
568704003636	active site
568704003637	(T/H)XGH motif; other site
568704003638	Predicted secreted protein containing a PDZ domain [Signal transduction mechanisms]; Region: SdrC; COG3480
568704003639	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
568704003640	protein binding site [polypeptide binding]; other site
568704003641	SLBB domain; Region: SLBB; pfam10531
568704003642	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
568704003643	Helix-hairpin-helix motif; Region: HHH; pfam00633
568704003644	Competence protein; Region: Competence; pfam03772
568704003645	Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658
568704003646	Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333
568704003647	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
568704003648	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
568704003649	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
568704003650	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
568704003651	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
568704003652	16S/18S rRNA binding site [nucleotide binding]; other site
568704003653	S13e-L30e interaction site [polypeptide binding]; other site
568704003654	25S rRNA binding site [nucleotide binding]; other site
568704003655	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
568704003656	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
568704003657	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
568704003658	elongation factor Tu; Reviewed; Region: PRK00049
568704003659	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
568704003660	G1 box; other site
568704003661	GEF interaction site [polypeptide binding]; other site
568704003662	GTP/Mg2+ binding site [chemical binding]; other site
568704003663	Switch I region; other site
568704003664	G2 box; other site
568704003665	G3 box; other site
568704003666	Switch II region; other site
568704003667	G4 box; other site
568704003668	G5 box; other site
568704003669	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
568704003670	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
568704003671	Antibiotic Binding Site [chemical binding]; other site
568704003672	Protein of unknown function (DUF3737); Region: DUF3737; pfam12541
568704003673	NAD-dependent deacetylase; Provisional; Region: PRK00481
568704003674	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
568704003675	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
568704003676	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
568704003677	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
568704003678	DNA binding residues [nucleotide binding]
568704003679	putative dimer interface [polypeptide binding]; other site
568704003680	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
568704003681	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
568704003682	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
568704003683	Walker A/P-loop; other site
568704003684	ATP binding site [chemical binding]; other site
568704003685	Q-loop/lid; other site
568704003686	ABC transporter signature motif; other site
568704003687	Walker B; other site
568704003688	D-loop; other site
568704003689	H-loop/switch region; other site
568704003690	trigger factor; Provisional; Region: tig; PRK01490
568704003691	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
568704003692	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
568704003693	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
568704003694	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
568704003695	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568704003696	Walker A motif; other site
568704003697	ATP binding site [chemical binding]; other site
568704003698	Walker B motif; other site
568704003699	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
568704003700	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
568704003701	Elongation factor Tu GTP binding domain; Region: GTP_EFTU; pfam00009
568704003702	G1 box; other site
568704003703	GTP/Mg2+ binding site [chemical binding]; other site
568704003704	Switch I region; other site
568704003705	G2 box; other site
568704003706	G3 box; other site
568704003707	Switch II region; other site
568704003708	G4 box; other site
568704003709	G5 box; other site
568704003710	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in a group of uncharacterized proteins from bacteria and archaea; Region: NTP-PPase_u4; cd11541
568704003711	putative metal binding site [ion binding]; other site
568704003712	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
568704003713	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
568704003714	substrate binding pocket [chemical binding]; other site
568704003715	membrane-bound complex binding site; other site
568704003716	hinge residues; other site
568704003717	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
568704003718	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568704003719	dimer interface [polypeptide binding]; other site
568704003720	conserved gate region; other site
568704003721	putative PBP binding loops; other site
568704003722	ABC-ATPase subunit interface; other site
568704003723	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
568704003724	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
568704003725	Walker A/P-loop; other site
568704003726	ATP binding site [chemical binding]; other site
568704003727	Q-loop/lid; other site
568704003728	ABC transporter signature motif; other site
568704003729	Walker B; other site
568704003730	D-loop; other site
568704003731	H-loop/switch region; other site
568704003732	Pleckstrin homology-like domain; Region: PH-like; cl17171
568704003733	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
568704003734	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
568704003735	GIY-YIG motif/motif A; other site
568704003736	active site
568704003737	catalytic site [active]
568704003738	putative DNA binding site [nucleotide binding]; other site
568704003739	metal binding site [ion binding]; metal-binding site
568704003740	UvrB/uvrC motif; Region: UVR; pfam02151
568704003741	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
568704003742	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
568704003743	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
568704003744	active site
568704003745	phosphorylation site [posttranslational modification]
568704003746	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
568704003747	active site
568704003748	P-loop; other site
568704003749	phosphorylation site [posttranslational modification]
568704003750	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
568704003751	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
568704003752	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
568704003753	putative substrate binding site [chemical binding]; other site
568704003754	putative ATP binding site [chemical binding]; other site
568704003755	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
568704003756	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
568704003757	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
568704003758	GTPase CgtA; Reviewed; Region: obgE; PRK12297
568704003759	GTP1/OBG; Region: GTP1_OBG; pfam01018
568704003760	Obg GTPase; Region: Obg; cd01898
568704003761	G1 box; other site
568704003762	GTP/Mg2+ binding site [chemical binding]; other site
568704003763	Switch I region; other site
568704003764	G2 box; other site
568704003765	G3 box; other site
568704003766	Switch II region; other site
568704003767	G4 box; other site
568704003768	G5 box; other site
568704003769	Domain of unknown function (DUF1967); Region: DUF1967; pfam09269
568704003770	Acyltransferase family; Region: Acyl_transf_3; pfam01757
568704003771	yrhL-like subfamily of SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_yrhL_like; cd01840
568704003772	catalytic triad [active]
568704003773	catalytic triad [active]
568704003774	oxyanion hole [active]
568704003775	ribonuclease Z; Region: RNase_Z; TIGR02651
568704003776	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
568704003777	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
568704003778	NAD(P) binding site [chemical binding]; other site
568704003779	active site
568704003780	Protein of unknown function (DUF1049); Region: DUF1049; pfam06305
568704003781	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
568704003782	Clp amino terminal domain; Region: Clp_N; pfam02861
568704003783	Clp amino terminal domain; Region: Clp_N; pfam02861
568704003784	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568704003785	Walker A motif; other site
568704003786	ATP binding site [chemical binding]; other site
568704003787	Walker B motif; other site
568704003788	arginine finger; other site
568704003789	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568704003790	Walker A motif; other site
568704003791	ATP binding site [chemical binding]; other site
568704003792	Walker B motif; other site
568704003793	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
568704003794	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
568704003795	Domain of unknown function (DUF1836); Region: DUF1836; pfam08876
568704003796	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
568704003797	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
568704003798	active site
568704003799	metal binding site [ion binding]; metal-binding site
568704003800	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
568704003801	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
568704003802	Protein of unknown function (DUF2929); Region: DUF2929; pfam11151
568704003803	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III; Region: PHP_PolIIIA; cd07431
568704003804	DNA polymerase alpha chain like domain; Region: POLIIIAc; smart00481
568704003805	active site
568704003806	PHP Thumb interface [polypeptide binding]; other site
568704003807	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
568704003808	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
568704003809	generic binding surface I; other site
568704003810	generic binding surface II; other site
568704003811	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
568704003812	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
568704003813	active site
568704003814	ADP/pyrophosphate binding site [chemical binding]; other site
568704003815	dimerization interface [polypeptide binding]; other site
568704003816	allosteric effector site; other site
568704003817	fructose-1,6-bisphosphate binding site; other site
568704003818	pyruvate kinase; Provisional; Region: PRK06354
568704003819	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
568704003820	domain interfaces; other site
568704003821	active site
568704003822	Phosphohistidine swiveling domain [Signal transduction mechanisms]; Region: COG3848
568704003823	Protein of unknown function (DUF441); Region: DUF441; pfam04284
568704003824	Predicted RNA-bindining protein (contains S1 and HTH domains) [General function prediction only]; Region: COG2996
568704003825	S1 domain; Region: S1_2; pfam13509
568704003826	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
568704003827	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
568704003828	active site
568704003829	Int/Topo IB signature motif; other site
568704003830	segregation and condensation protein A; Reviewed; Region: scpA; PRK00104
568704003831	segregation and condensation protein B; Reviewed; Region: scpB; PRK00135
568704003832	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
568704003833	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
568704003834	RNA binding surface [nucleotide binding]; other site
568704003835	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
568704003836	active site
568704003837	Predicted membrane protein [Function unknown]; Region: COG3601
568704003838	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
568704003839	4Fe-4S single cluster domain; Region: Fer4_13; pfam13370
568704003840	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4955
568704003841	DEAD-like helicases superfamily; Region: DEXDc; smart00487
568704003842	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
568704003843	ATP binding site [chemical binding]; other site
568704003844	putative Mg++ binding site [ion binding]; other site
568704003845	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
568704003846	nucleotide binding region [chemical binding]; other site
568704003847	ATP-binding site [chemical binding]; other site
568704003848	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
568704003849	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
568704003850	cytidylate kinase; Provisional; Region: cmk; PRK00023
568704003851	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
568704003852	CMP-binding site; other site
568704003853	The sites determining sugar specificity; other site
568704003854	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06676
568704003855	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
568704003856	RNA binding site [nucleotide binding]; other site
568704003857	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
568704003858	RNA binding site [nucleotide binding]; other site
568704003859	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
568704003860	RNA binding site [nucleotide binding]; other site
568704003861	S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692
568704003862	RNA binding site [nucleotide binding]; other site
568704003863	GTP-binding protein Der; Reviewed; Region: PRK00093
568704003864	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
568704003865	G1 box; other site
568704003866	GTP/Mg2+ binding site [chemical binding]; other site
568704003867	Switch I region; other site
568704003868	G2 box; other site
568704003869	Switch II region; other site
568704003870	G3 box; other site
568704003871	G4 box; other site
568704003872	G5 box; other site
568704003873	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
568704003874	G1 box; other site
568704003875	GTP/Mg2+ binding site [chemical binding]; other site
568704003876	Switch I region; other site
568704003877	G2 box; other site
568704003878	G3 box; other site
568704003879	Switch II region; other site
568704003880	G4 box; other site
568704003881	G5 box; other site
568704003882	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
568704003883	IHF dimer interface [polypeptide binding]; other site
568704003884	IHF - DNA interface [nucleotide binding]; other site
568704003885	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
568704003886	binding surface
568704003887	TPR motif; other site
568704003888	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
568704003889	binding surface
568704003890	TPR repeat; Region: TPR_11; pfam13414
568704003891	TPR motif; other site
568704003892	TPR repeat; Region: TPR_11; pfam13414
568704003893	Uncharacterized conserved protein [Function unknown]; Region: COG1284
568704003894	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
568704003895	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
568704003896	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
568704003897	tRNA CCA-pyrophosphorylase; Provisional; Region: PRK13299
568704003898	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
568704003899	active site
568704003900	NTP binding site [chemical binding]; other site
568704003901	metal binding triad [ion binding]; metal-binding site
568704003902	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
568704003903	tRNA nucleotidyltransferase domain 2 putative; Region: tRNA_NucTran2_2; pfam13735
568704003904	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
568704003905	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
568704003906	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
568704003907	ABC transporter; Region: ABC_tran_2; pfam12848
568704003908	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
568704003909	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
568704003910	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
568704003911	active site
568704003912	dimerization interface [polypeptide binding]; other site
568704003913	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
568704003914	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
568704003915	folate binding site [chemical binding]; other site
568704003916	NADP+ binding site [chemical binding]; other site
568704003917	Haemolysin-III related; Region: HlyIII; cl03831
568704003918	EDD domain protein, DegV family; Region: DegV; TIGR00762
568704003919	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
568704003920	Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_YpmR_like; cd04506
568704003921	active site
568704003922	catalytic triad [active]
568704003923	oxyanion hole [active]
568704003924	Uncharacterized protein conserved in bacteria (DUF2140); Region: DUF2140; pfam09911
568704003925	methionine sulfoxide reductase A; Provisional; Region: PRK14054
568704003926	hypothetical protein; Provisional; Region: PRK13672
568704003927	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
568704003928	C-terminal peptidase (prc); Region: prc; TIGR00225
568704003929	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
568704003930	protein binding site [polypeptide binding]; other site
568704003931	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
568704003932	Catalytic dyad [active]
568704003933	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
568704003934	ribosome biogenesis GTP-binding protein YlqF; Region: GTPase_YlqF; TIGR03596
568704003935	Circularly permuted YlqF GTPase; Region: YlqF; cd01856
568704003936	GTP/Mg2+ binding site [chemical binding]; other site
568704003937	G4 box; other site
568704003938	G5 box; other site
568704003939	G1 box; other site
568704003940	Switch I region; other site
568704003941	G2 box; other site
568704003942	G3 box; other site
568704003943	Switch II region; other site
568704003944	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
568704003945	RNA/DNA hybrid binding site [nucleotide binding]; other site
568704003946	active site
568704003947	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
568704003948	DNA protecting protein DprA; Region: dprA; TIGR00732
568704003949	DNA topoisomerase I; Validated; Region: PRK05582
568704003950	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
568704003951	active site
568704003952	interdomain interaction site; other site
568704003953	putative metal-binding site [ion binding]; other site
568704003954	nucleotide binding site [chemical binding]; other site
568704003955	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
568704003956	domain I; other site
568704003957	DNA binding groove [nucleotide binding]
568704003958	phosphate binding site [ion binding]; other site
568704003959	domain II; other site
568704003960	domain III; other site
568704003961	nucleotide binding site [chemical binding]; other site
568704003962	catalytic site [active]
568704003963	domain IV; other site
568704003964	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
568704003965	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
568704003966	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
568704003967	Glucose inhibited division protein A; Region: GIDA; pfam01134
568704003968	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
568704003969	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
568704003970	active site
568704003971	Int/Topo IB signature motif; other site
568704003972	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
568704003973	active site
568704003974	HslU subunit interaction site [polypeptide binding]; other site
568704003975	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
568704003976	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568704003977	Walker A motif; other site
568704003978	ATP binding site [chemical binding]; other site
568704003979	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
568704003980	Walker B motif; other site
568704003981	arginine finger; other site
568704003982	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
568704003983	Aldose 1-epimerase, similar to Lactococcus lactis lacX; Region: Aldose_epim_lacX; cd09024
568704003984	active site
568704003985	catalytic residues [active]
568704003986	membrane protein; Provisional; Region: PRK14392
568704003987	DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559
568704003988	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568704003989	Mg2+ binding site [ion binding]; other site
568704003990	G-X-G motif; other site
568704003991	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
568704003992	anchoring element; other site
568704003993	dimer interface [polypeptide binding]; other site
568704003994	ATP binding site [chemical binding]; other site
568704003995	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
568704003996	active site
568704003997	putative metal-binding site [ion binding]; other site
568704003998	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
568704003999	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
568704004000	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
568704004001	CAP-like domain; other site
568704004002	active site
568704004003	primary dimer interface [polypeptide binding]; other site
568704004004	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
568704004005	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
568704004006	Pyruvate formate lyase 1; Region: PFL1; cd01678
568704004007	coenzyme A binding site [chemical binding]; other site
568704004008	active site
568704004009	catalytic residues [active]
568704004010	glycine loop; other site
568704004011	pyruvate formate-lyase 1-activating enzyme; Region: PFLA; TIGR02493
568704004012	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
568704004013	FeS/SAM binding site; other site
568704004014	Transcriptional regulator [Transcription]; Region: LysR; COG0583
568704004015	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568704004016	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
568704004017	dimerization interface [polypeptide binding]; other site
568704004018	putative manganese-dependent inorganic pyrophosphatase; Provisional; Region: PRK05427
568704004019	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
568704004020	DHHA2 domain; Region: DHHA2; pfam02833
568704004021	site-specific tyrosine recombinase XerS; Reviewed; Region: xerS; PRK05084
568704004022	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
568704004023	active site
568704004024	DNA binding site [nucleotide binding]
568704004025	Int/Topo IB signature motif; other site
568704004026	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
568704004027	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
568704004028	Walker A/P-loop; other site
568704004029	ATP binding site [chemical binding]; other site
568704004030	Q-loop/lid; other site
568704004031	ABC transporter signature motif; other site
568704004032	Walker B; other site
568704004033	D-loop; other site
568704004034	H-loop/switch region; other site
568704004035	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
568704004036	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568704004037	ATP binding site [chemical binding]; other site
568704004038	Mg2+ binding site [ion binding]; other site
568704004039	G-X-G motif; other site
568704004040	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
568704004041	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568704004042	active site
568704004043	phosphorylation site [posttranslational modification]
568704004044	intermolecular recognition site; other site
568704004045	dimerization interface [polypeptide binding]; other site
568704004046	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
568704004047	DNA binding site [nucleotide binding]
568704004048	H+ Antiporter protein; Region: 2A0121; TIGR00900
568704004049	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704004050	putative substrate translocation pore; other site
568704004051	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568704004052	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
568704004053	Coenzyme A binding pocket [chemical binding]; other site
568704004054	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568704004055	Coenzyme A binding pocket [chemical binding]; other site
568704004056	Nitroreductase-like family 1. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_1; cd02137
568704004057	dimer interface [polypeptide binding]; other site
568704004058	FMN binding site [chemical binding]; other site
568704004059	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
568704004060	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
568704004061	histidinol-phosphate aminotransferase; Provisional; Region: PRK03158
568704004062	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
568704004063	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568704004064	homodimer interface [polypeptide binding]; other site
568704004065	catalytic residue [active]
568704004066	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
568704004067	metal binding site [ion binding]; metal-binding site
568704004068	phosphoribosyl-AMP cyclohydrolase; Reviewed; Region: hisI; PRK00051
568704004069	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
568704004070	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
568704004071	substrate binding site [chemical binding]; other site
568704004072	glutamase interaction surface [polypeptide binding]; other site
568704004073	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
568704004074	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
568704004075	catalytic residues [active]
568704004076	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13141
568704004077	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
568704004078	putative active site [active]
568704004079	oxyanion strand; other site
568704004080	catalytic triad [active]
568704004081	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
568704004082	4-fold oligomerization interface [polypeptide binding]; other site
568704004083	putative active site pocket [active]
568704004084	metal binding residues [ion binding]; metal-binding site
568704004085	3-fold/trimer interface [polypeptide binding]; other site
568704004086	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
568704004087	histidinol dehydrogenase; Region: hisD; TIGR00069
568704004088	NAD binding site [chemical binding]; other site
568704004089	dimerization interface [polypeptide binding]; other site
568704004090	product binding site; other site
568704004091	substrate binding site [chemical binding]; other site
568704004092	zinc binding site [ion binding]; other site
568704004093	catalytic residues [active]
568704004094	ATP phosphoribosyltransferase catalytic subunit; Reviewed; Region: hisG; PRK01686
568704004095	ATP phosphoribosyltransferase [Amino acid transport and metabolism]; Region: HisG; COG0040
568704004096	ATP phosphoribosyltransferase, regulatory subunit; Region: hisZ_biosyn_reg; TIGR00443
568704004097	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
568704004098	dimer interface [polypeptide binding]; other site
568704004099	motif 1; other site
568704004100	active site
568704004101	motif 2; other site
568704004102	motif 3; other site
568704004103	histidinol-phosphate aminotransferase; Provisional; Region: PRK03158
568704004104	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
568704004105	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568704004106	homodimer interface [polypeptide binding]; other site
568704004107	catalytic residue [active]
568704004108	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
568704004109	dimer interface [polypeptide binding]; other site
568704004110	ADP-ribose binding site [chemical binding]; other site
568704004111	active site
568704004112	nudix motif; other site
568704004113	metal binding site [ion binding]; metal-binding site
568704004114	EDD domain protein, DegV family; Region: DegV; TIGR00762
568704004115	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
568704004116	Fibronectin-binding protein A N-terminus (FbpA); Region: FbpA; pfam05833
568704004117	Domain of unknown function (DUF814); Region: DUF814; pfam05670
568704004118	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Sulfolobus solfataricus (Ss) and its homologs from archaea and bacteria; Region: NTP-PPase_SsMazG; cd11535
568704004119	metal binding site [ion binding]; metal-binding site
568704004120	Predicted membrane protein, putative toxin regulator [General function prediction only]; Region: PfoR; COG3641
568704004121	Phosphotransferase system, EIIC; Region: PTS_EIIC_2; pfam13303
568704004122	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
568704004123	active site
568704004124	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
568704004125	active site
568704004126	dimer interface [polypeptide binding]; other site
568704004127	Dihydroorotate dehydrogenase (DHOD) class 1B FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine...; Region: DHOD_1B_like; cd04740
568704004128	dihydroorotate dehydrogenase (subfamily 1) family protein; Region: pyrD_sub1_fam; TIGR01037
568704004129	heterodimer interface [polypeptide binding]; other site
568704004130	active site
568704004131	FMN binding site [chemical binding]; other site
568704004132	homodimer interface [polypeptide binding]; other site
568704004133	substrate binding site [chemical binding]; other site
568704004134	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
568704004135	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
568704004136	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
568704004137	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
568704004138	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
568704004139	ATP-grasp domain; Region: ATP-grasp_4; cl17255
568704004140	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
568704004141	IMP binding site; other site
568704004142	dimer interface [polypeptide binding]; other site
568704004143	interdomain contacts; other site
568704004144	partial ornithine binding site; other site
568704004145	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
568704004146	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
568704004147	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
568704004148	catalytic site [active]
568704004149	subunit interface [polypeptide binding]; other site
568704004150	dihydroorotase; Validated; Region: pyrC; PRK09357
568704004151	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
568704004152	Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317
568704004153	active site
568704004154	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
568704004155	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
568704004156	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
568704004157	uracil transporter; Provisional; Region: PRK10720
568704004158	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
568704004159	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
568704004160	active site
568704004161	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
568704004162	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
568704004163	RNA binding surface [nucleotide binding]; other site
568704004164	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
568704004165	active site
568704004166	lipoprotein signal peptidase; Provisional; Region: PRK14797
568704004167	lipoprotein signal peptidase; Provisional; Region: PRK14787
568704004168	formate--tetrahydrofolate ligase; Provisional; Region: PRK13505
568704004169	Formyltetrahydrofolate synthetase (FTHFS) catalyzes the ATP-dependent activation of formate ion via its addition to the N10 position of tetrahydrofolate. FTHFS is a highly expressed key enzyme in both the Wood-Ljungdahl pathway of autotrophic CO2...; Region: FTHFS; cd00477
568704004170	Potassium binding sites [ion binding]; other site
568704004171	Cesium cation binding sites [ion binding]; other site
568704004172	RNAse HI family that includes Archaeal RNase HI; Region: RNase_HI_archaeal_like; cd09279
568704004173	RNA/DNA hybrid binding site [nucleotide binding]; other site
568704004174	active site
568704004175	Nitroreductase-like family 4.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_4; cd02140
568704004176	dimer interface [polypeptide binding]; other site
568704004177	FMN binding site [chemical binding]; other site
568704004178	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
568704004179	cardiolipin synthase; Region: bac_cardiolipin; TIGR04265
568704004180	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
568704004181	putative active site [active]
568704004182	catalytic site [active]
568704004183	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
568704004184	putative active site [active]
568704004185	catalytic site [active]
568704004186	Mga helix-turn-helix domain; Region: Mga; pfam05043
568704004187	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
568704004188	catalytic residues [active]
568704004189	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK07306
568704004190	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
568704004191	Class I ribonucleotide reductase; Region: RNR_I; cd01679
568704004192	active site
568704004193	dimer interface [polypeptide binding]; other site
568704004194	catalytic residues [active]
568704004195	effector binding site; other site
568704004196	R2 peptide binding site; other site
568704004197	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
568704004198	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
568704004199	dimer interface [polypeptide binding]; other site
568704004200	putative radical transfer pathway; other site
568704004201	diiron center [ion binding]; other site
568704004202	tyrosyl radical; other site
568704004203	Transcriptional regulator [Transcription]; Region: LysR; COG0583
568704004204	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568704004205	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
568704004206	dimerization interface [polypeptide binding]; other site
568704004207	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
568704004208	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
568704004209	active site
568704004210	Zn binding site [ion binding]; other site
568704004211	lipoyltransferase and lipoate-protein ligase; Region: lipoyltrans; TIGR00545
568704004212	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
568704004213	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
568704004214	Phosphoglycerate Dehydrogenase, 2-hydroxyacid dehydrogenase family; Region: PGDH_1; cd12155
568704004215	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
568704004216	putative ligand binding site [chemical binding]; other site
568704004217	NAD binding site [chemical binding]; other site
568704004218	catalytic site [active]
568704004219	Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0116
568704004220	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
568704004221	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
568704004222	cell division protein GpsB; Provisional; Region: PRK14127
568704004223	DivIVA domain; Region: DivI1A_domain; TIGR03544
568704004224	hypothetical protein; Provisional; Region: PRK13660
568704004225	Holliday junction-specific endonuclease; Reviewed; Region: recU; PRK02234
568704004226	Transglycosylase; Region: Transgly; pfam00912
568704004227	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
568704004228	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
568704004229	Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286
568704004230	catalytic motif [active]
568704004231	Zn binding site [ion binding]; other site
568704004232	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
568704004233	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
568704004234	minor groove reading motif; other site
568704004235	helix-hairpin-helix signature motif; other site
568704004236	substrate binding pocket [chemical binding]; other site
568704004237	active site
568704004238	Putative primosome component and related proteins [DNA replication, recombination, and repair]; Region: DnaD; COG3935
568704004239	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
568704004240	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
568704004241	AsnRS_cyto_like_N: N-terminal, anticodon recognition domain of the type found in human and Saccharomyces cerevisiae cytoplasmic asparaginyl-tRNA synthetase (AsnRS), in Brugia malayai AsnRs and, in various putative bacterial AsnRSs.  This domain is a...; Region: AsnRS_cyto_like_N; cd04323
568704004242	putative dimer interface [polypeptide binding]; other site
568704004243	putative anticodon binding site; other site
568704004244	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
568704004245	homodimer interface [polypeptide binding]; other site
568704004246	motif 1; other site
568704004247	motif 2; other site
568704004248	active site
568704004249	motif 3; other site
568704004250	aspartate aminotransferase; Provisional; Region: PRK05764
568704004251	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
568704004252	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568704004253	homodimer interface [polypeptide binding]; other site
568704004254	catalytic residue [active]
568704004255	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5353
568704004256	DnaQ family exonuclease/DinG family helicase, putative; Region: dinG_rel; TIGR01407
568704004257	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
568704004258	active site
568704004259	catalytic site [active]
568704004260	substrate binding site [chemical binding]; other site
568704004261	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
568704004262	helicase-exonuclease AddAB, AddA subunit, Firmicutes type; Region: addA_Gpos; TIGR02785
568704004263	DEAD/DEAH box helicase; Region: DEAD; pfam00270
568704004264	ATP binding site [chemical binding]; other site
568704004265	Family description; Region: UvrD_C_2; pfam13538
568704004266	helicase-exonuclease AddAB, AddB subunit; Region: addB_Gpos; TIGR02773
568704004267	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
568704004268	Mevalonate kinase [Lipid metabolism]; Region: ERG12; COG1577
568704004269	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
568704004270	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
568704004271	diphosphomevalonate decarboxylase; Region: PLN02407
568704004272	diphosphomevalonate decarboxylase; Region: mevDPdecarb; TIGR01240
568704004273	isopentenyl pyrophosphate isomerase; Provisional; Region: PRK05437
568704004274	Isopentenyl-diphosphate:dimethylallyl diphosphate isomerase type 2 (IDI-2) FMN-binding domain. Two types of IDIs have been characterized at present. The long known IDI-1 is only dependent on divalent metals for activity, whereas IDI-2 requires a metal; Region: IDI-2_FMN; cd02811
568704004275	homotetramer interface [polypeptide binding]; other site
568704004276	FMN binding site [chemical binding]; other site
568704004277	homodimer contacts [polypeptide binding]; other site
568704004278	putative active site [active]
568704004279	putative substrate binding site [chemical binding]; other site
568704004280	tRNA and rRNA cytosine-C5-methylases [Translation, ribosomal structure and biogenesis]; Region: Sun; COG0144
568704004281	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568704004282	S-adenosylmethionine binding site [chemical binding]; other site
568704004283	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
568704004284	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
568704004285	4-oxalocrotonate tautomerase; Provisional; Region: PRK02220
568704004286	active site 1 [active]
568704004287	dimer interface [polypeptide binding]; other site
568704004288	hexamer interface [polypeptide binding]; other site
568704004289	active site 2 [active]
568704004290	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
568704004291	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
568704004292	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704004293	Walker A/P-loop; other site
568704004294	ATP binding site [chemical binding]; other site
568704004295	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
568704004296	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704004297	Walker A/P-loop; other site
568704004298	ATP binding site [chemical binding]; other site
568704004299	Q-loop/lid; other site
568704004300	ABC transporter signature motif; other site
568704004301	Walker B; other site
568704004302	D-loop; other site
568704004303	H-loop/switch region; other site
568704004304	Uncharacterized conserved protein [Function unknown]; Region: COG0327
568704004305	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
568704004306	Predicted SAM-dependent methyltransferase [General function prediction only]; Region: COG2384
568704004307	Family of unknown function (DUF633); Region: DUF633; pfam04816
568704004308	RNA polymerase sigma factor RpoD; Validated; Region: PRK09210
568704004309	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
568704004310	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
568704004311	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
568704004312	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
568704004313	DNA binding residues [nucleotide binding]
568704004314	DNA primase; Validated; Region: dnaG; PRK05667
568704004315	CHC2 zinc finger; Region: zf-CHC2; pfam01807
568704004316	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
568704004317	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
568704004318	active site
568704004319	metal binding site [ion binding]; metal-binding site
568704004320	interdomain interaction site; other site
568704004321	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
568704004322	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
568704004323	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
568704004324	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
568704004325	dimer interface [polypeptide binding]; other site
568704004326	motif 1; other site
568704004327	active site
568704004328	motif 2; other site
568704004329	motif 3; other site
568704004330	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
568704004331	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
568704004332	ABC-2 family transporter protein; Region: ABC2_membrane_5; pfam13346
568704004333	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
568704004334	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
568704004335	Walker A/P-loop; other site
568704004336	ATP binding site [chemical binding]; other site
568704004337	Q-loop/lid; other site
568704004338	ABC transporter signature motif; other site
568704004339	Walker B; other site
568704004340	D-loop; other site
568704004341	H-loop/switch region; other site
568704004342	Recombination protein O N terminal; Region: RecO_N; pfam11967
568704004343	DNA repair protein RecO; Region: reco; TIGR00613
568704004344	Recombination protein O C terminal; Region: RecO_C; pfam02565
568704004345	GTPase Era; Reviewed; Region: era; PRK00089
568704004346	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
568704004347	G1 box; other site
568704004348	GTP/Mg2+ binding site [chemical binding]; other site
568704004349	Switch I region; other site
568704004350	G2 box; other site
568704004351	Switch II region; other site
568704004352	G3 box; other site
568704004353	G4 box; other site
568704004354	G5 box; other site
568704004355	KH domain; Region: KH_2; pfam07650
568704004356	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
568704004357	active site
568704004358	catalytic motif [active]
568704004359	Zn binding site [ion binding]; other site
568704004360	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
568704004361	metal-binding heat shock protein; Provisional; Region: PRK00016
568704004362	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
568704004363	PhoH-like protein; Region: PhoH; pfam02562
568704004364	Yqey-like protein; Region: YqeY; pfam09424
568704004365	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
568704004366	Kinase/pyrophosphorylase; Region: Kinase-PPPase; pfam03618
568704004367	endonuclease IV; Provisional; Region: PRK01060
568704004368	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
568704004369	AP (apurinic/apyrimidinic) site pocket; other site
568704004370	DNA interaction; other site
568704004371	Metal-binding active site; metal-binding site
568704004372	Uncharacterized conserved protein [Function unknown]; Region: COG1284
568704004373	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
568704004374	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
568704004375	methionine sulfoxide reductase B; Provisional; Region: PRK00222
568704004376	SelR domain; Region: SelR; pfam01641
568704004377	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
568704004378	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
568704004379	dimer interface [polypeptide binding]; other site
568704004380	anticodon binding site; other site
568704004381	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
568704004382	homodimer interface [polypeptide binding]; other site
568704004383	motif 1; other site
568704004384	active site
568704004385	motif 2; other site
568704004386	GAD domain; Region: GAD; pfam02938
568704004387	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
568704004388	motif 3; other site
568704004389	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
568704004390	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
568704004391	dimer interface [polypeptide binding]; other site
568704004392	motif 1; other site
568704004393	active site
568704004394	motif 2; other site
568704004395	motif 3; other site
568704004396	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
568704004397	anticodon binding site; other site
568704004398	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
568704004399	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704004400	Walker A/P-loop; other site
568704004401	ATP binding site [chemical binding]; other site
568704004402	Q-loop/lid; other site
568704004403	ABC transporter signature motif; other site
568704004404	Walker B; other site
568704004405	D-loop; other site
568704004406	H-loop/switch region; other site
568704004407	HIT family: HIT (Histidine triad) proteins, named for a motif related to the sequence HxHxH/Qxx (x, a hydrophobic amino acid), are a superfamily of nucleotide hydrolases and transferases, which act on the alpha-phosphate of ribonucleotides. On the basis...; Region: HIT_like; cl00228
568704004408	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3807
568704004409	Bacterial SH3 domain; Region: SH3_3; pfam08239
568704004410	Bacterial SH3 domain; Region: SH3_3; pfam08239
568704004411	Bacterial SH3 domain; Region: SH3_3; pfam08239
568704004412	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
568704004413	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
568704004414	active site
568704004415	metal binding site [ion binding]; metal-binding site
568704004416	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
568704004417	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568704004418	motif II; other site
568704004419	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
568704004420	putative active site [active]
568704004421	dimerization interface [polypeptide binding]; other site
568704004422	putative tRNAtyr binding site [nucleotide binding]; other site
568704004423	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
568704004424	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
568704004425	Zn2+ binding site [ion binding]; other site
568704004426	Mg2+ binding site [ion binding]; other site
568704004427	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
568704004428	synthetase active site [active]
568704004429	NTP binding site [chemical binding]; other site
568704004430	metal binding site [ion binding]; metal-binding site
568704004431	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
568704004432	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
568704004433	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
568704004434	RNA methyltransferase, RsmE family; Region: TIGR00046
568704004435	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
568704004436	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568704004437	S-adenosylmethionine binding site [chemical binding]; other site
568704004438	Protein of unknown function (DUF3013); Region: DUF3013; pfam11217
568704004439	Alkyladenine DNA glycosylase catalyzes the first step in base excision repair; Region: AAG; cd00540
568704004440	active site
568704004441	DNA binding site [nucleotide binding]
568704004442	Protein of unknown function (DUF1093); Region: DUF1093; cl02185
568704004443	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
568704004444	Flavodoxin-like fold; Region: Flavodoxin_2; pfam02525
568704004445	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
568704004446	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
568704004447	WHG domain; Region: WHG; pfam13305
568704004448	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
568704004449	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
568704004450	accessory Sec system glycosylation protein GtfA; Region: TIGR02918
568704004451	This family is most closely related to the GT1 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding.  In...; Region: GT1_gtfA_like; cd04949
568704004452	Domain of unknown function (DUF1975); Region: DUF1975; pfam09318
568704004453	This family is most closely related to the GT1 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding.  In...; Region: GT1_gtfA_like; cd04949
568704004454	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
568704004455	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
568704004456	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
568704004457	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
568704004458	SCP: SCP-like extracellular protein domain, found in eukaryotes and prokaryotes. This family includes plant pathogenesis-related protein 1 (PR-1), which accumulates after infections with pathogens, and may act as an anti-fungal agent or be involved in...; Region: SCP; cl00133
568704004459	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
568704004460	KxYKxGKxW signal peptide; Region: KxYKxGKxW; TIGR03715
568704004461	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
568704004462	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
568704004463	KxYKxGKxW signal peptide; Region: KxYKxGKxW; TIGR03715
568704004464	surface protein repeat Ser-Ala-175; Region: SerAla_Lrha_rpt; TIGR04319
568704004465	N-formylglutamate amidohydrolase; Region: FGase; pfam05013
568704004466	Staphylococcal protein of unknown function (DUF960); Region: DUF960; pfam06124
568704004467	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
568704004468	putative deacylase active site [active]
568704004469	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
568704004470	active site
568704004471	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
568704004472	DHH family; Region: DHH; pfam01368
568704004473	Single-strand DNA-specific exonuclease, C terminal domain; Region: ssDNA-exonuc_C; cl11538
568704004474	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
568704004475	GTP-binding protein LepA; Provisional; Region: PRK05433
568704004476	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
568704004477	G1 box; other site
568704004478	putative GEF interaction site [polypeptide binding]; other site
568704004479	GTP/Mg2+ binding site [chemical binding]; other site
568704004480	Switch I region; other site
568704004481	G2 box; other site
568704004482	G3 box; other site
568704004483	Switch II region; other site
568704004484	G4 box; other site
568704004485	G5 box; other site
568704004486	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
568704004487	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
568704004488	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
568704004489	chaperone protein DnaJ; Provisional; Region: PRK14276
568704004490	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
568704004491	HSP70 interaction site [polypeptide binding]; other site
568704004492	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
568704004493	substrate binding site [polypeptide binding]; other site
568704004494	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
568704004495	Zn binding sites [ion binding]; other site
568704004496	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
568704004497	dimer interface [polypeptide binding]; other site
568704004498	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
568704004499	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
568704004500	nucleotide binding site [chemical binding]; other site
568704004501	NEF interaction site [polypeptide binding]; other site
568704004502	SBD interface [polypeptide binding]; other site
568704004503	GrpE; Region: GrpE; pfam01025
568704004504	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
568704004505	dimer interface [polypeptide binding]; other site
568704004506	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
568704004507	heat-inducible transcription repressor; Provisional; Region: hrcA; PRK00082
568704004508	HTH domain; Region: HTH_11; pfam08279
568704004509	coproporphyrinogen III oxidase; Provisional; Region: PRK08599
568704004510	HemN C-terminal domain; Region: HemN_C; pfam06969
568704004511	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
568704004512	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
568704004513	active site
568704004514	Riboflavin kinase; Region: Flavokinase; smart00904
568704004515	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK02484
568704004516	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
568704004517	RNA binding site [nucleotide binding]; other site
568704004518	active site
568704004519	integral membrane protein, YkoY family; Region: R_switched_YkoY; TIGR03716
568704004520	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
568704004521	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
568704004522	translation initiation factor IF-2; Region: IF-2; TIGR00487
568704004523	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
568704004524	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
568704004525	G1 box; other site
568704004526	putative GEF interaction site [polypeptide binding]; other site
568704004527	GTP/Mg2+ binding site [chemical binding]; other site
568704004528	Switch I region; other site
568704004529	G2 box; other site
568704004530	G3 box; other site
568704004531	Switch II region; other site
568704004532	G4 box; other site
568704004533	G5 box; other site
568704004534	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
568704004535	Translation-initiation factor 2; Region: IF-2; pfam11987
568704004536	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
568704004537	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; Region: Ribosomal_L7Ae; cl00600
568704004538	Ylxr homologs; group of conserved hypothetical bacterial proteins of unknown function; structure revealed putative RNA binding cleft; proteins are encoded by an operon that includes other proteins involved in transcription and/or translation; Region: YlxR; cd00279
568704004539	putative RNA binding cleft [nucleotide binding]; other site
568704004540	transcription elongation factor NusA; Provisional; Region: nusA; PRK12327
568704004541	NusA N-terminal domain; Region: NusA_N; pfam08529
568704004542	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
568704004543	RNA binding site [nucleotide binding]; other site
568704004544	homodimer interface [polypeptide binding]; other site
568704004545	NusA-like KH domain; Region: KH_5; pfam13184
568704004546	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
568704004547	G-X-X-G motif; other site
568704004548	ribosome maturation protein RimP; Reviewed; Region: PRK00092
568704004549	Sm and related proteins; Region: Sm_like; cl00259
568704004550	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
568704004551	putative oligomer interface [polypeptide binding]; other site
568704004552	putative RNA binding site [nucleotide binding]; other site
568704004553	DNA polymerase III PolC; Validated; Region: polC; PRK00448
568704004554	DNA polymerase III polC-type N-terminus; Region: DNA_pol3_alph_N; pfam11490
568704004555	polC_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold nucleic acid binding domain of Bacillus subtilis type C replicative DNA polymerase III alpha subunit (polC). Replication in B. subtilis and Staphylococcus aureus requires two...; Region: polC_OBF; cd04484
568704004556	generic binding surface II; other site
568704004557	generic binding surface I; other site
568704004558	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
568704004559	active site
568704004560	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
568704004561	active site
568704004562	catalytic site [active]
568704004563	substrate binding site [chemical binding]; other site
568704004564	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III at PolC gene; Region: PHP_PolIIIA_POLC; cd07435
568704004565	prolyl-tRNA synthetase; Provisional; Region: PRK09194
568704004566	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
568704004567	dimer interface [polypeptide binding]; other site
568704004568	motif 1; other site
568704004569	active site
568704004570	motif 2; other site
568704004571	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
568704004572	putative deacylase active site [active]
568704004573	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
568704004574	active site
568704004575	motif 3; other site
568704004576	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
568704004577	anticodon binding site; other site
568704004578	RIP metalloprotease RseP; Region: TIGR00054
568704004579	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
568704004580	active site
568704004581	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
568704004582	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
568704004583	protein binding site [polypeptide binding]; other site
568704004584	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
568704004585	putative substrate binding region [chemical binding]; other site
568704004586	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
568704004587	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
568704004588	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
568704004589	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
568704004590	catalytic residue [active]
568704004591	putative FPP diphosphate  binding site; other site
568704004592	putative FPP binding hydrophobic cleft; other site
568704004593	dimer interface [polypeptide binding]; other site
568704004594	putative IPP diphosphate binding site; other site
568704004595	ribosome recycling factor; Reviewed; Region: frr; PRK00083
568704004596	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
568704004597	hinge region; other site
568704004598	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
568704004599	putative nucleotide binding site [chemical binding]; other site
568704004600	uridine monophosphate binding site [chemical binding]; other site
568704004601	homohexameric interface [polypeptide binding]; other site
568704004602	elongation factor Ts; Provisional; Region: tsf; PRK09377
568704004603	UBA/TS-N domain; Region: UBA; pfam00627
568704004604	Elongation factor TS; Region: EF_TS; pfam00889
568704004605	Elongation factor TS; Region: EF_TS; pfam00889
568704004606	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
568704004607	rRNA interaction site [nucleotide binding]; other site
568704004608	S8 interaction site; other site
568704004609	putative laminin-1 binding site; other site
568704004610	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
568704004611	GIY-YIG motif/motif A; other site
568704004612	putative active site [active]
568704004613	putative metal binding site [ion binding]; other site
568704004614	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
568704004615	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568704004616	S-adenosylmethionine binding site [chemical binding]; other site
568704004617	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
568704004618	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
568704004619	putative acyl-acceptor binding pocket; other site
568704004620	amino acid transporter; Region: 2A0306; TIGR00909
568704004621	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
568704004622	Protein of unknown function (DUF1003); Region: DUF1003; pfam06210
568704004623	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
568704004624	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
568704004625	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
568704004626	Walker A/P-loop; other site
568704004627	ATP binding site [chemical binding]; other site
568704004628	Q-loop/lid; other site
568704004629	ABC transporter signature motif; other site
568704004630	Walker B; other site
568704004631	D-loop; other site
568704004632	H-loop/switch region; other site
568704004633	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
568704004634	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
568704004635	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704004636	Walker A/P-loop; other site
568704004637	ATP binding site [chemical binding]; other site
568704004638	Q-loop/lid; other site
568704004639	ABC transporter signature motif; other site
568704004640	Walker B; other site
568704004641	D-loop; other site
568704004642	H-loop/switch region; other site
568704004643	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3763
568704004644	Bacterial protein of unknown function (DUF896); Region: DUF896; pfam05979
568704004645	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
568704004646	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
568704004647	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
568704004648	RimM N-terminal domain; Region: RimM; pfam01782
568704004649	PRC-barrel domain; Region: PRC; pfam05239
568704004650	KH domain; Region: KH_4; pfam13083
568704004651	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
568704004652	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
568704004653	signal recognition particle protein; Provisional; Region: PRK10867
568704004654	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
568704004655	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
568704004656	P loop; other site
568704004657	GTP binding site [chemical binding]; other site
568704004658	Signal peptide binding domain; Region: SRP_SPB; pfam02978
568704004659	Putative helix-turn-helix protein, YlxM / p13 like; Region: UPF0122; pfam04297
568704004660	putative DNA-binding protein; Validated; Region: PRK00118
568704004661	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
568704004662	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
568704004663	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
568704004664	P loop; other site
568704004665	GTP binding site [chemical binding]; other site
568704004666	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
568704004667	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
568704004668	Walker A/P-loop; other site
568704004669	ATP binding site [chemical binding]; other site
568704004670	Q-loop/lid; other site
568704004671	SMC proteins Flexible Hinge Domain; Region: SMC_hinge; smart00968
568704004672	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
568704004673	ABC transporter signature motif; other site
568704004674	Walker B; other site
568704004675	D-loop; other site
568704004676	H-loop/switch region; other site
568704004677	ribonuclease III, bacterial; Region: RNaseIII; TIGR02191
568704004678	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
568704004679	dimerization interface [polypeptide binding]; other site
568704004680	active site
568704004681	metal binding site [ion binding]; metal-binding site
568704004682	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
568704004683	The substrate binding component of an ABC-type lactococcal OppA-like transport system contains; Region: PBP2_Lactococcal_OppA_like; cd08510
568704004684	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
568704004685	peptide binding site [polypeptide binding]; other site
568704004686	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
568704004687	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
568704004688	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568704004689	dimer interface [polypeptide binding]; other site
568704004690	conserved gate region; other site
568704004691	putative PBP binding loops; other site
568704004692	ABC-ATPase subunit interface; other site
568704004693	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
568704004694	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568704004695	dimer interface [polypeptide binding]; other site
568704004696	conserved gate region; other site
568704004697	putative PBP binding loops; other site
568704004698	ABC-ATPase subunit interface; other site
568704004699	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
568704004700	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
568704004701	Walker A/P-loop; other site
568704004702	ATP binding site [chemical binding]; other site
568704004703	Q-loop/lid; other site
568704004704	ABC transporter signature motif; other site
568704004705	Walker B; other site
568704004706	D-loop; other site
568704004707	H-loop/switch region; other site
568704004708	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
568704004709	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
568704004710	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
568704004711	Walker A/P-loop; other site
568704004712	ATP binding site [chemical binding]; other site
568704004713	Q-loop/lid; other site
568704004714	ABC transporter signature motif; other site
568704004715	Walker B; other site
568704004716	D-loop; other site
568704004717	H-loop/switch region; other site
568704004718	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
568704004719	acyl carrier protein; Provisional; Region: acpP; PRK00982
568704004720	putative phosphate acyltransferase; Provisional; Region: PRK05331
568704004721	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
568704004722	Y-family of DNA polymerases; Region: PolY; cl12025
568704004723	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
568704004724	generic binding surface II; other site
568704004725	ssDNA binding site; other site
568704004726	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
568704004727	ATP binding site [chemical binding]; other site
568704004728	putative Mg++ binding site [ion binding]; other site
568704004729	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
568704004730	nucleotide binding region [chemical binding]; other site
568704004731	ATP-binding site [chemical binding]; other site
568704004732	DAK2 domain fusion protein YloV; Region: YloV; TIGR03599
568704004733	DAK2 domain; Region: Dak2; pfam02734
568704004734	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1302
568704004735	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
568704004736	Thiamine pyrophosphokinase; Region: TPK; cd07995
568704004737	thiamine pyrophosphokinase; Region: thi_PPkinase; TIGR01378
568704004738	active site
568704004739	dimerization interface [polypeptide binding]; other site
568704004740	thiamine binding site [chemical binding]; other site
568704004741	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
568704004742	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
568704004743	substrate binding site [chemical binding]; other site
568704004744	hexamer interface [polypeptide binding]; other site
568704004745	metal binding site [ion binding]; metal-binding site
568704004746	GTPase RsgA; Reviewed; Region: PRK00098
568704004747	S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466
568704004748	RNA binding site [nucleotide binding]; other site
568704004749	homodimer interface [polypeptide binding]; other site
568704004750	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
568704004751	GTPase/Zn-binding domain interface [polypeptide binding]; other site
568704004752	GTP/Mg2+ binding site [chemical binding]; other site
568704004753	G4 box; other site
568704004754	G5 box; other site
568704004755	G1 box; other site
568704004756	Switch I region; other site
568704004757	G2 box; other site
568704004758	G3 box; other site
568704004759	Switch II region; other site
568704004760	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
568704004761	Catalytic domain of Protein Kinases; Region: PKc; cd00180
568704004762	active site
568704004763	ATP binding site [chemical binding]; other site
568704004764	substrate binding site [chemical binding]; other site
568704004765	activation loop (A-loop); other site
568704004766	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2815
568704004767	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
568704004768	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
568704004769	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
568704004770	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
568704004771	active site
568704004772	16S rRNA methyltransferase B; Provisional; Region: PRK14902
568704004773	NusB family; Region: NusB; pfam01029
568704004774	putative RNA binding site [nucleotide binding]; other site
568704004775	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568704004776	S-adenosylmethionine binding site [chemical binding]; other site
568704004777	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
568704004778	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
568704004779	putative active site [active]
568704004780	substrate binding site [chemical binding]; other site
568704004781	putative cosubstrate binding site; other site
568704004782	catalytic site [active]
568704004783	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
568704004784	substrate binding site [chemical binding]; other site
568704004785	Primosomal protein N' (replication factor Y) - superfamily II helicase [DNA replication, recombination, and repair]; Region: PriA; COG1198
568704004786	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
568704004787	ATP binding site [chemical binding]; other site
568704004788	putative Mg++ binding site [ion binding]; other site
568704004789	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
568704004790	nucleotide binding region [chemical binding]; other site
568704004791	ATP-binding site [chemical binding]; other site
568704004792	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
568704004793	Flavoprotein; Region: Flavoprotein; pfam02441
568704004794	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
568704004795	DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392
568704004796	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
568704004797	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
568704004798	catalytic site [active]
568704004799	G-X2-G-X-G-K; other site
568704004800	Hypothetical patatin similar to Z1214 protein of Escherichia coli; Region: Pat_hypo_Ecoli_Z1214_like; cd07209
568704004801	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
568704004802	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
568704004803	Walker A/P-loop; other site
568704004804	ATP binding site [chemical binding]; other site
568704004805	Q-loop/lid; other site
568704004806	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
568704004807	ABC transporter signature motif; other site
568704004808	Walker B; other site
568704004809	D-loop; other site
568704004810	H-loop/switch region; other site
568704004811	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
568704004812	arginine repressor; Provisional; Region: PRK04280
568704004813	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
568704004814	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
568704004815	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
568704004816	RNA binding surface [nucleotide binding]; other site
568704004817	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568704004818	S-adenosylmethionine binding site [chemical binding]; other site
568704004819	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
568704004820	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
568704004821	substrate binding pocket [chemical binding]; other site
568704004822	chain length determination region; other site
568704004823	substrate-Mg2+ binding site; other site
568704004824	catalytic residues [active]
568704004825	aspartate-rich region 1; other site
568704004826	active site lid residues [active]
568704004827	aspartate-rich region 2; other site
568704004828	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
568704004829	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
568704004830	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
568704004831	generic binding surface II; other site
568704004832	generic binding surface I; other site
568704004833	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14169
568704004834	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
568704004835	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
568704004836	homodimer interface [polypeptide binding]; other site
568704004837	NADP binding site [chemical binding]; other site
568704004838	substrate binding site [chemical binding]; other site
568704004839	transcription antitermination protein NusB; Reviewed; Region: nusB; PRK00202
568704004840	Asp23 family; Region: Asp23; pfam03780
568704004841	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
568704004842	RNA binding site [nucleotide binding]; other site
568704004843	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
568704004844	RNA binding site [nucleotide binding]; other site
568704004845	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
568704004846	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
568704004847	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
568704004848	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
568704004849	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
568704004850	active site
568704004851	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
568704004852	Protein of unknown function (DUF464); Region: DUF464; pfam04327
568704004853	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
568704004854	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
568704004855	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
568704004856	Walker A/P-loop; other site
568704004857	ATP binding site [chemical binding]; other site
568704004858	Q-loop/lid; other site
568704004859	ABC transporter signature motif; other site
568704004860	Walker B; other site
568704004861	D-loop; other site
568704004862	H-loop/switch region; other site
568704004863	x-prolyl-dipeptidyl aminopeptidase; Provisional; Region: PRK05371
568704004864	X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal; Region: PepX_N; pfam09168
568704004865	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; pfam08530
568704004866	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
568704004867	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
568704004868	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
568704004869	Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators; Region: HTH_GlnR-like; cd01105
568704004870	DNA binding residues [nucleotide binding]
568704004871	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
568704004872	putative dimer interface [polypeptide binding]; other site
568704004873	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
568704004874	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
568704004875	catalytic residue [active]
568704004876	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
568704004877	Aluminium resistance protein; Region: Alum_res; pfam06838
568704004878	Cystathionine beta-lyase family protein involved in aluminum resistance [Inorganic ion transport and metabolism]; Region: COG4100
568704004879	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
568704004880	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
568704004881	Protein of unknown function (DUF3042); Region: DUF3042; pfam11240
568704004882	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
568704004883	active site residue [active]
568704004884	ROK family protein (putative glucokinase); Region: ROK_glcA_fam; TIGR00744
568704004885	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
568704004886	nucleotide binding site [chemical binding]; other site
568704004887	Bacterial protein of unknown function (DUF910); Region: DUF910; pfam06014
568704004888	Rhomboid family; Region: Rhomboid; pfam01694
568704004889	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
568704004890	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
568704004891	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
568704004892	Bacterial membrane protein YfhO; Region: YfhO; pfam09586
568704004893	Iron-sulphur cluster biosynthesis; Region: Fe-S_biosyn; cl00400
568704004894	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
568704004895	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568704004896	active site
568704004897	phosphorylation site [posttranslational modification]
568704004898	intermolecular recognition site; other site
568704004899	dimerization interface [polypeptide binding]; other site
568704004900	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
568704004901	DNA binding residues [nucleotide binding]
568704004902	dimerization interface [polypeptide binding]; other site
568704004903	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
568704004904	Histidine kinase; Region: HisKA_3; pfam07730
568704004905	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568704004906	ATP binding site [chemical binding]; other site
568704004907	Mg2+ binding site [ion binding]; other site
568704004908	G-X-G motif; other site
568704004909	Predicted membrane protein [Function unknown]; Region: COG4758
568704004910	Cell wall-active antibiotics response protein (DUF2154); Region: DUF2154; pfam09922
568704004911	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
568704004912	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
568704004913	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
568704004914	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
568704004915	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
568704004916	Sugar specificity; other site
568704004917	Pyrimidine base specificity; other site
568704004918	ATP-binding site [chemical binding]; other site
568704004919	YceG-like family; Region: YceG; pfam02618
568704004920	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
568704004921	dimerization interface [polypeptide binding]; other site
568704004922	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
568704004923	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
568704004924	putative tRNA-binding site [nucleotide binding]; other site
568704004925	B3/4 domain; Region: B3_4; pfam03483
568704004926	tRNA synthetase B5 domain; Region: B5; smart00874
568704004927	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
568704004928	dimer interface [polypeptide binding]; other site
568704004929	motif 1; other site
568704004930	motif 3; other site
568704004931	motif 2; other site
568704004932	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
568704004933	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
568704004934	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
568704004935	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
568704004936	dimer interface [polypeptide binding]; other site
568704004937	motif 1; other site
568704004938	active site
568704004939	motif 2; other site
568704004940	motif 3; other site
568704004941	Predicted transcriptional regulators [Transcription]; Region: COG1733
568704004942	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
568704004943	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215
568704004944	Zn2+ binding site [ion binding]; other site
568704004945	Mg2+ binding site [ion binding]; other site
568704004946	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
568704004947	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
568704004948	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
568704004949	Acylphosphatase; Region: Acylphosphatase; pfam00708
568704004950	OxaA-like protein precursor; Provisional; Region: PRK02463
568704004951	60Kd inner membrane protein; Region: 60KD_IMP; cl00489
568704004952	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
568704004953	HAMP domain; Region: HAMP; pfam00672
568704004954	dimerization interface [polypeptide binding]; other site
568704004955	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
568704004956	dimer interface [polypeptide binding]; other site
568704004957	phosphorylation site [posttranslational modification]
568704004958	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568704004959	ATP binding site [chemical binding]; other site
568704004960	Mg2+ binding site [ion binding]; other site
568704004961	G-X-G motif; other site
568704004962	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
568704004963	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568704004964	active site
568704004965	phosphorylation site [posttranslational modification]
568704004966	intermolecular recognition site; other site
568704004967	dimerization interface [polypeptide binding]; other site
568704004968	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
568704004969	DNA binding site [nucleotide binding]
568704004970	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
568704004971	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
568704004972	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
568704004973	Uncharacterized ACR, COG1399; Region: DUF177; cl00616
568704004974	hypothetical protein; Provisional; Region: PRK13670
568704004975	HIGH Nucleotidyl Transferase; Region: HIGH_NTase1; cl17673
568704004976	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568704004977	S-adenosylmethionine binding site [chemical binding]; other site
568704004978	Uncharacterized homolog of plant Iojap protein [Function unknown]; Region: COG0799
568704004979	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
568704004980	Zn2+ binding site [ion binding]; other site
568704004981	Mg2+ binding site [ion binding]; other site
568704004982	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
568704004983	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
568704004984	active site
568704004985	(T/H)XGH motif; other site
568704004986	Predicted RNA-binding protein containing KH domain, possibly ribosomal protein [Translation, ribosomal structure and biogenesis]; Region: COG1534
568704004987	GTPase YqeH; Provisional; Region: PRK13796
568704004988	Circularly permuted YqeH GTPase; Region: YqeH; cd01855
568704004989	GTP/Mg2+ binding site [chemical binding]; other site
568704004990	G4 box; other site
568704004991	G5 box; other site
568704004992	G1 box; other site
568704004993	Switch I region; other site
568704004994	G2 box; other site
568704004995	G3 box; other site
568704004996	Switch II region; other site
568704004997	Predicted hydrolase of the HAD superfamily [General function prediction only]; Region: COG2179
568704004998	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568704004999	active site
568704005000	motif I; other site
568704005001	motif II; other site
568704005002	N-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_N_like; cd08346
568704005003	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
568704005004	Zn binding site [ion binding]; other site
568704005005	C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_C_like; cd08347
568704005006	Zn binding site [ion binding]; other site
568704005007	N-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_N_like; cd08346
568704005008	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
568704005009	Zn binding site [ion binding]; other site
568704005010	C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_C_like; cd08347
568704005011	Zn binding site [ion binding]; other site
568704005012	putative hydrolase; Provisional; Region: PRK11460
568704005013	Predicted esterase [General function prediction only]; Region: COG0400
568704005014	alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases; Region: MDR_like_2; cd05289
568704005015	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
568704005016	putative NAD(P) binding site [chemical binding]; other site
568704005017	Possible lysine decarboxylase; Region: Lysine_decarbox; cl00695
568704005018	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
568704005019	23S rRNA binding site [nucleotide binding]; other site
568704005020	L21 binding site [polypeptide binding]; other site
568704005021	L13 binding site [polypeptide binding]; other site
568704005022	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
568704005023	translation initiation factor IF-3; Region: infC; TIGR00168
568704005024	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
568704005025	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
568704005026	stage V sporulation protein K; Region: spore_V_K; TIGR02881
568704005027	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568704005028	Walker A motif; other site
568704005029	ATP binding site [chemical binding]; other site
568704005030	Walker B motif; other site
568704005031	arginine finger; other site
568704005032	stage V sporulation protein K; Region: spore_V_K; TIGR02881
568704005033	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568704005034	Walker A motif; other site
568704005035	ATP binding site [chemical binding]; other site
568704005036	Walker B motif; other site
568704005037	arginine finger; other site
568704005038	WYL domain; Region: WYL; pfam13280
568704005039	SseB protein; Region: SseB; cl06279
568704005040	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
568704005041	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
568704005042	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
568704005043	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
568704005044	active site
568704005045	dimer interface [polypeptide binding]; other site
568704005046	motif 1; other site
568704005047	motif 2; other site
568704005048	motif 3; other site
568704005049	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
568704005050	anticodon binding site; other site
568704005051	primosomal protein DnaI; Reviewed; Region: PRK08939
568704005052	Primosomal protein DnaI N-terminus; Region: DnaI_N; pfam07319
568704005053	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568704005054	Walker A motif; other site
568704005055	ATP binding site [chemical binding]; other site
568704005056	Walker B motif; other site
568704005057	Replication initiation/membrane attachment protein [DNA replication, recombination, and repair]; Region: DnaB; COG3611
568704005058	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
568704005059	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
568704005060	ATP cone domain; Region: ATP-cone; pfam03477
568704005061	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
568704005062	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
568704005063	CoA-binding site [chemical binding]; other site
568704005064	ATP-binding [chemical binding]; other site
568704005065	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
568704005066	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
568704005067	DNA binding site [nucleotide binding]
568704005068	catalytic residue [active]
568704005069	H2TH interface [polypeptide binding]; other site
568704005070	putative catalytic residues [active]
568704005071	turnover-facilitating residue; other site
568704005072	intercalation triad [nucleotide binding]; other site
568704005073	8OG recognition residue [nucleotide binding]; other site
568704005074	putative reading head residues; other site
568704005075	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
568704005076	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
568704005077	Family A polymerase primarily fills DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A; cl02626
568704005078	5'-3' exonuclease; Region: 53EXOc; smart00475
568704005079	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
568704005080	active site
568704005081	metal binding site 1 [ion binding]; metal-binding site
568704005082	putative 5' ssDNA interaction site; other site
568704005083	metal binding site 3; metal-binding site
568704005084	metal binding site 2 [ion binding]; metal-binding site
568704005085	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
568704005086	putative DNA binding site [nucleotide binding]; other site
568704005087	putative metal binding site [ion binding]; other site
568704005088	inactive DEDDy 3'-5' exonuclease domain of Bacillus stearothermophilus DNA polymerase I and similar family-A DNA polymerases; Region: DNA_polA_I_Bacillus_like_exo; cd06140
568704005089	Family A polymerase primarily fills DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A; cl02626
568704005090	active site
568704005091	DNA binding site [nucleotide binding]
568704005092	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
568704005093	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
568704005094	Bacterial protein of unknown function (DUF916); Region: DUF916; pfam06030
568704005095	Protein of unknown function C-terminal (DUF3324); Region: DUF3324; pfam11797
568704005096	WxL domain surface cell wall-binding; Region: WxL; pfam13731
568704005097	Mga helix-turn-helix domain; Region: Mga; pfam05043
568704005098	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
568704005099	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
568704005100	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
568704005101	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
568704005102	This domain directs oriented DNA translocation and forms a winged helix structure; Region: Ftsk_gamma; smart00843
568704005103	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
568704005104	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
568704005105	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
568704005106	catalytic residues [active]
568704005107	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
568704005108	putative tRNA-binding site [nucleotide binding]; other site
568704005109	Predicted small secreted protein [Function unknown]; Region: COG5584
568704005110	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568704005111	S-adenosylmethionine binding site [chemical binding]; other site
568704005112	Thiamine kinase and related kinases [Coenzyme transport and metabolism]; Region: ycfN; COG0510
568704005113	Phosphotransferase enzyme family; Region: APH; pfam01636
568704005114	active site
568704005115	substrate binding site [chemical binding]; other site
568704005116	ATP binding site [chemical binding]; other site
568704005117	Bacterial ABC transporter protein EcsB; Region: EcsB; pfam05975
568704005118	Bacterial ABC transporter protein EcsB; Region: EcsB; pfam05975
568704005119	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
568704005120	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
568704005121	Walker A/P-loop; other site
568704005122	ATP binding site [chemical binding]; other site
568704005123	Q-loop/lid; other site
568704005124	ABC transporter signature motif; other site
568704005125	Walker B; other site
568704005126	D-loop; other site
568704005127	H-loop/switch region; other site
568704005128	HINT (histidine triad nucleotide-binding protein) subgroup: Members of this CD belong to the superfamily of histidine triad hydrolases that act on alpha-phosphate of ribonucleotides. This subgroup includes members from all three forms of cellular life; Region: HINT_subgroup; cd01277
568704005129	HIT family signature motif; other site
568704005130	catalytic residue [active]
568704005131	YtxH-like protein; Region: YtxH; pfam12732
568704005132	peptidylprolyl isomerase; Provisional; Region: prsA; PRK04405
568704005133	SurA N-terminal domain; Region: SurA_N_3; cl07813
568704005134	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
568704005135	3'-5' exoribonuclease YhaM; Provisional; Region: PRK13480
568704005136	YhaM_OBF_like: A subfamily of OB folds similar to that found in Bacillus subtilis YhaM and Staphylococcus aureus cmp-binding factor-1 (SaCBF1). Both these proteins are 3'-to-5'exoribonucleases. YhaM requires Mn2+ or Co2+ for activity and is...; Region: YhaM_OBF_like; cd04492
568704005137	generic binding surface I; other site
568704005138	generic binding surface II; other site
568704005139	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
568704005140	Zn2+ binding site [ion binding]; other site
568704005141	Mg2+ binding site [ion binding]; other site
568704005142	Protein of unknown function (DUF964); Region: DUF964; cl01483
568704005143	Transglycosylase; Region: Transgly; pfam00912
568704005144	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
568704005145	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
568704005146	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
568704005147	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
568704005148	active site
568704005149	Arginine repressor [Transcription]; Region: ArgR; COG1438
568704005150	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
568704005151	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
568704005152	arginyl-tRNA synthetase; Reviewed; Region: PRK12451
568704005153	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
568704005154	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
568704005155	active site
568704005156	HIGH motif; other site
568704005157	KMSK motif region; other site
568704005158	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
568704005159	tRNA binding surface [nucleotide binding]; other site
568704005160	anticodon binding site; other site
568704005161	dihydroorotate dehydrogenase (subfamily 1) family protein; Region: pyrD_sub1_fam; TIGR01037
568704005162	Dihydroorotate dehydrogenase (DHOD) class 1A FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine...; Region: DHOD_1A_like; cd04741
568704005163	active site
568704005164	FMN binding site [chemical binding]; other site
568704005165	substrate binding site [chemical binding]; other site
568704005166	catalytic residues [active]
568704005167	homodimer interface [polypeptide binding]; other site
568704005168	Membrane domain of glycerophosphoryl diester phosphodiesterase; Region: GPDPase_memb; pfam10110
568704005169	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
568704005170	Glycerophosphodiester phosphodiesterase domain of uncharacterized bacterial glycerophosphodiester phosphodiesterases; Region: GDPD_memb_like; cd08579
568704005171	putative active site [active]
568704005172	catalytic site [active]
568704005173	putative metal binding site [ion binding]; other site
568704005174	adaptor protein; Provisional; Region: PRK02315
568704005175	Arsenate Reductase (ArsC) family, Spx subfamily; Spx is a unique RNA polymerase (RNAP)-binding protein present in bacilli and some mollicutes. It inhibits transcription by binding to the C-terminal domain of the alpha subunit of RNAP, disrupting complex...; Region: ArsC_Spx; cd03032
568704005176	ArsC family; Region: ArsC; pfam03960
568704005177	putative catalytic residues [active]
568704005178	thiol/disulfide switch; other site
568704005179	Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only]; Region: ElaC; COG1234
568704005180	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
568704005181	FtsX-like permease family; Region: FtsX; pfam02687
568704005182	FtsX-like permease family; Region: FtsX; pfam02687
568704005183	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
568704005184	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
568704005185	Walker A/P-loop; other site
568704005186	ATP binding site [chemical binding]; other site
568704005187	Q-loop/lid; other site
568704005188	ABC transporter signature motif; other site
568704005189	Walker B; other site
568704005190	D-loop; other site
568704005191	H-loop/switch region; other site
568704005192	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
568704005193	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568704005194	active site
568704005195	phosphorylation site [posttranslational modification]
568704005196	intermolecular recognition site; other site
568704005197	dimerization interface [polypeptide binding]; other site
568704005198	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
568704005199	DNA binding site [nucleotide binding]
568704005200	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
568704005201	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
568704005202	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568704005203	ATP binding site [chemical binding]; other site
568704005204	Mg2+ binding site [ion binding]; other site
568704005205	G-X-G motif; other site
568704005206	anaerobic ribonucleotide reductase-activating protein; Provisional; Region: nrdG; cl15804
568704005207	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
568704005208	copper-(or silver)-translocating P-type ATPase; Region: ATPase-IB1_Cu; TIGR01511
568704005209	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
568704005210	copper transport repressor, CopY/TcrY family; Region: CopY_TcrY; TIGR02698
568704005211	Penicillinase repressor; Region: Pencillinase_R; pfam03965
568704005212	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
568704005213	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
568704005214	ATP-grasp domain; Region: ATP-grasp_4; cl17255
568704005215	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
568704005216	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
568704005217	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
568704005218	purine monophosphate binding site [chemical binding]; other site
568704005219	dimer interface [polypeptide binding]; other site
568704005220	putative catalytic residues [active]
568704005221	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
568704005222	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
568704005223	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
568704005224	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
568704005225	active site
568704005226	substrate binding site [chemical binding]; other site
568704005227	cosubstrate binding site; other site
568704005228	catalytic site [active]
568704005229	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
568704005230	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
568704005231	putative ATP binding site [chemical binding]; other site
568704005232	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
568704005233	dimerization interface [polypeptide binding]; other site
568704005234	amidophosphoribosyltransferase; Provisional; Region: PRK07272
568704005235	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
568704005236	active site
568704005237	tetramer interface [polypeptide binding]; other site
568704005238	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
568704005239	active site
568704005240	phosphoribosylformylglycinamidine synthase II; Provisional; Region: PRK01213
568704005241	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
568704005242	dimerization interface [polypeptide binding]; other site
568704005243	ATP binding site [chemical binding]; other site
568704005244	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
568704005245	dimerization interface [polypeptide binding]; other site
568704005246	ATP binding site [chemical binding]; other site
568704005247	phosphoribosylformylglycinamidine synthase I; Provisional; Region: PRK03619
568704005248	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
568704005249	putative active site [active]
568704005250	catalytic triad [active]
568704005251	Phosphoribosylformylglycinamidine (FGAM) synthase; Region: PurS; pfam02700
568704005252	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
568704005253	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
568704005254	ATP binding site [chemical binding]; other site
568704005255	active site
568704005256	substrate binding site [chemical binding]; other site
568704005257	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
568704005258	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
568704005259	NAD binding site [chemical binding]; other site
568704005260	ATP-grasp domain; Region: ATP-grasp; pfam02222
568704005261	AIR carboxylase; Region: AIRC; pfam00731
568704005262	Thiamine transporter protein (Thia_YuaJ); Region: Thia_YuaJ; pfam09515
568704005263	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
568704005264	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704005265	putative substrate translocation pore; other site
568704005266	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704005267	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
568704005268	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
568704005269	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
568704005270	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
568704005271	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
568704005272	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
568704005273	dimerization domain swap beta strand [polypeptide binding]; other site
568704005274	regulatory protein interface [polypeptide binding]; other site
568704005275	active site
568704005276	regulatory phosphorylation site [posttranslational modification]; other site
568704005277	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568704005278	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
568704005279	Walker A motif; other site
568704005280	ATP binding site [chemical binding]; other site
568704005281	Walker B motif; other site
568704005282	arginine finger; other site
568704005283	UvrB/uvrC motif; Region: UVR; pfam02151
568704005284	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568704005285	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
568704005286	Walker A motif; other site
568704005287	ATP binding site [chemical binding]; other site
568704005288	Walker B motif; other site
568704005289	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
568704005290	Domain of unknown function (DUF1827); Region: DUF1827; pfam08860
568704005291	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
568704005292	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
568704005293	G1 box; other site
568704005294	putative GEF interaction site [polypeptide binding]; other site
568704005295	GTP/Mg2+ binding site [chemical binding]; other site
568704005296	Switch I region; other site
568704005297	G2 box; other site
568704005298	G3 box; other site
568704005299	Switch II region; other site
568704005300	G4 box; other site
568704005301	G5 box; other site
568704005302	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
568704005303	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
568704005304	Domain of unknown function DUF21; Region: DUF21; pfam01595
568704005305	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
568704005306	Transporter associated domain; Region: CorC_HlyC; pfam03471
568704005307	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
568704005308	Domain of unknown function DUF20; Region: UPF0118; pfam01594
568704005309	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568704005310	Coenzyme A binding pocket [chemical binding]; other site
568704005311	hypothetical protein; Provisional; Region: PRK13662
568704005312	RecX family; Region: RecX; cl00936
568704005313	Mga helix-turn-helix domain; Region: Mga; pfam05043
568704005314	TRAM domain; Region: TRAM; pfam01938
568704005315	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
568704005316	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568704005317	S-adenosylmethionine binding site [chemical binding]; other site
568704005318	Nucleoside 2-deoxyribosyltransferase; Region: Nuc_deoxyrib_tr; pfam05014
568704005319	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
568704005320	pyruvate oxidase; Region: pyruv_oxi_spxB; TIGR02720
568704005321	PYR/PP interface [polypeptide binding]; other site
568704005322	dimer interface [polypeptide binding]; other site
568704005323	tetramer interface [polypeptide binding]; other site
568704005324	TPP binding site [chemical binding]; other site
568704005325	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
568704005326	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
568704005327	TPP-binding site [chemical binding]; other site
568704005328	"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are...; Region: init_cond_enzymes; cd00827
568704005329	3-hydroxy-3-methylglutaryl CoA synthase, prokaryotic clade; Region: HMG-CoA-S_prok; TIGR01835
568704005330	dimer interface [polypeptide binding]; other site
568704005331	active site
568704005332	Hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR); Region: HMG-CoA_reductase; cl00205
568704005333	helix swapped region; other site
568704005334	homodimer interface [polypeptide binding]; other site
568704005335	substrate binding pocket [chemical binding]; other site
568704005336	catalytic residues [active]
568704005337	NADH/NADPH cofactor binding site [chemical binding]; other site
568704005338	putative acyltransferase; Provisional; Region: PRK05790
568704005339	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
568704005340	dimer interface [polypeptide binding]; other site
568704005341	active site
568704005342	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
568704005343	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
568704005344	Metal-binding active site; metal-binding site
568704005345	Restriction endonuclease; Region: Mrr_cat; pfam04471
568704005346	aldose 1-epimerase superfamily; Region: Aldose_epim; cl14648
568704005347	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK08588
568704005348	Peptidase M20 acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase (ArgE/DapE)-like; Region: M20_ArgE_DapE_like; cd08659
568704005349	metal binding site [ion binding]; metal-binding site
568704005350	dimer interface [polypeptide binding]; other site
568704005351	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
568704005352	Predicted membrane protein [Function unknown]; Region: COG4684
568704005353	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
568704005354	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568704005355	Coenzyme A binding pocket [chemical binding]; other site
568704005356	hypothetical protein; Provisional; Region: PRK04351
568704005357	SprT homologues; Region: SprT; cl01182
568704005358	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: PhnK; COG1101
568704005359	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704005360	Walker A/P-loop; other site
568704005361	ATP binding site [chemical binding]; other site
568704005362	Q-loop/lid; other site
568704005363	ABC transporter signature motif; other site
568704005364	Walker B; other site
568704005365	D-loop; other site
568704005366	H-loop/switch region; other site
568704005367	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cd06574
568704005368	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
568704005369	TM-ABC transporter signature motif; other site
568704005370	Type I periplasmic ligand-binding domain of uncharacterized ABC-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_uncharacterized_transporter; cd06325
568704005371	zinc binding site [ion binding]; other site
568704005372	putative ligand binding site [chemical binding]; other site
568704005373	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
568704005374	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
568704005375	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
568704005376	ATPase, P-type (transporting), HAD superfamily, subfamily IC; Region: ATPase_P-type; TIGR01494
568704005377	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
568704005378	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
568704005379	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
568704005380	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
568704005381	Beta-lactamase; Region: Beta-lactamase; pfam00144
568704005382	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
568704005383	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
568704005384	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
568704005385	homodimer interface [polypeptide binding]; other site
568704005386	NAD binding pocket [chemical binding]; other site
568704005387	ATP binding pocket [chemical binding]; other site
568704005388	Mg binding site [ion binding]; other site
568704005389	active-site loop [active]
568704005390	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
568704005391	Beta-lactamase; Region: Beta-lactamase; pfam00144
568704005392	nicotinate phosphoribosyltransferase; Validated; Region: PRK09243
568704005393	Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction...; Region: NAPRTase_A; cd01570
568704005394	active site
568704005395	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
568704005396	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568704005397	DNA-binding site [nucleotide binding]; DNA binding site
568704005398	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
568704005399	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
568704005400	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
568704005401	active site
568704005402	dimer interface [polypeptide binding]; other site
568704005403	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
568704005404	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
568704005405	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
568704005406	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
568704005407	Domain of Unknown Function (DUF1542); Region: DUF1542; pfam07564
568704005408	Mga helix-turn-helix domain; Region: Mga; pfam05043
568704005409	putative phosphoesterase; Region: acc_ester; TIGR03729
568704005410	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
568704005411	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704005412	putative substrate translocation pore; other site
568704005413	POT family; Region: PTR2; pfam00854
568704005414	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
568704005415	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
568704005416	Walker A/P-loop; other site
568704005417	ATP binding site [chemical binding]; other site
568704005418	Q-loop/lid; other site
568704005419	ABC transporter signature motif; other site
568704005420	Walker B; other site
568704005421	D-loop; other site
568704005422	H-loop/switch region; other site
568704005423	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
568704005424	FtsX-like permease family; Region: FtsX; pfam02687
568704005425	MFS/sugar transport protein; Region: MFS_2; pfam13347
568704005426	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
568704005427	Alpha-L-fucosidase; Region: Alpha_L_fucos; cl12119
568704005428	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
568704005429	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
568704005430	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_HprK; cl00270
568704005431	active site
568704005432	nucleotide-binding site [chemical binding]; other site
568704005433	Virus attachment protein p12 family; Region: P12; pfam12669
568704005434	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
568704005435	Nucleoside recognition; Region: Gate; pfam07670
568704005436	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
568704005437	Nucleoside recognition; Region: Gate; pfam07670
568704005438	Ferrous iron transport protein B; Region: FeoB_N; pfam02421
568704005439	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
568704005440	G1 box; other site
568704005441	GTP/Mg2+ binding site [chemical binding]; other site
568704005442	Switch I region; other site
568704005443	G2 box; other site
568704005444	G3 box; other site
568704005445	Switch II region; other site
568704005446	G4 box; other site
568704005447	G5 box; other site
568704005448	FeoA domain; Region: FeoA; pfam04023
568704005449	Fe2+ transport system protein A [Inorganic ion transport and metabolism]; Region: FeoA; COG1918
568704005450	yrhL-like subfamily of SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_yrhL_like; cd01840
568704005451	catalytic triad [active]
568704005452	catalytic triad [active]
568704005453	oxyanion hole [active]
568704005454	AAA domain; Region: AAA_17; cl17253
568704005455	AAA domain; Region: AAA_18; pfam13238
568704005456	biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs; Region: BVR-B_like_SDR_a; cd05244
568704005457	NADH(P)-binding; Region: NAD_binding_10; pfam13460
568704005458	NAD binding site [chemical binding]; other site
568704005459	substrate binding site [chemical binding]; other site
568704005460	putative active site [active]
568704005461	seryl-tRNA synthetase; Provisional; Region: PRK05431
568704005462	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
568704005463	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
568704005464	dimer interface [polypeptide binding]; other site
568704005465	active site
568704005466	motif 1; other site
568704005467	motif 2; other site
568704005468	motif 3; other site
568704005469	Mga helix-turn-helix domain; Region: Mga; pfam05043
568704005470	Mga helix-turn-helix domain; Region: Mga; pfam05043
568704005471	lysine transporter; Provisional; Region: PRK10836
568704005472	Alpha-acetolactate decarboxylase; Region: AAL_decarboxy; pfam03306
568704005473	acetolactate synthase; Reviewed; Region: PRK08617
568704005474	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
568704005475	PYR/PP interface [polypeptide binding]; other site
568704005476	dimer interface [polypeptide binding]; other site
568704005477	TPP binding site [chemical binding]; other site
568704005478	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
568704005479	Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; composed of proteins similar to Klebsiella pneumoniae ALS, a catabolic enzyme required for butanediol fermentation. ALS catalyzes the conversion of 2...; Region: TPP_ALS; cd02010
568704005480	TPP-binding site [chemical binding]; other site
568704005481	dimer interface [polypeptide binding]; other site
568704005482	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
568704005483	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
568704005484	Bacterial protein of unknown function (DUF916); Region: DUF916; pfam06030
568704005485	Protein of unknown function C-terminal (DUF3324); Region: DUF3324; pfam11797
568704005486	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
568704005487	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
568704005488	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
568704005489	active site
568704005490	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
568704005491	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
568704005492	ATP:dephospho-CoA triphosphoribosyl transferase; Region: CitG; cl00768
568704005493	Transcriptional regulators [Transcription]; Region: GntR; COG1802
568704005494	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568704005495	DNA-binding site [nucleotide binding]; DNA binding site
568704005496	FCD domain; Region: FCD; pfam07729
568704005497	oxaloacetate decarboxylase; Provisional; Region: PRK12331
568704005498	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
568704005499	active site
568704005500	catalytic residues [active]
568704005501	metal binding site [ion binding]; metal-binding site
568704005502	homodimer binding site [polypeptide binding]; other site
568704005503	2'-(5''-triphosphoribosyl)-3'- dephospho-CoA:apo-citrate lyase; Reviewed; Region: citX; PRK01392
568704005504	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
568704005505	Coenzyme A transferase; Region: CoA_trans; cl17247
568704005506	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
568704005507	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
568704005508	citrate lyase subunit gamma; Provisional; Region: PRK13253
568704005509	[citrate (pro-3S)-lyase] ligase; Region: cit_ly_ligase; TIGR00124
568704005510	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
568704005511	active site
568704005512	nucleotide binding site [chemical binding]; other site
568704005513	HIGH motif; other site
568704005514	KMSKS motif; other site
568704005515	Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit [Energy production and conversion]; Region: OadB; COG1883
568704005516	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06549
568704005517	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
568704005518	carboxyltransferase (CT) interaction site; other site
568704005519	biotinylation site [posttranslational modification]; other site
568704005520	H+/citrate symporter [Energy production and conversion]; Region: CitM; COG2851
568704005521	Citrate transporter; Region: CitMHS; pfam03600
568704005522	RNA 2'-phosphotransferase; Reviewed; Region: PRK00819
568704005523	RNA:NAD 2'-phosphotransferase [Translation, ribosomal structure and biogenesis]; Region: KptA; COG1859
568704005524	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
568704005525	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568704005526	Coenzyme A binding pocket [chemical binding]; other site
568704005527	Predicted dinucleotide-binding enzymes [General function prediction only]; Region: COG2085
568704005528	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; pfam03807
568704005529	Predicted transcriptional regulators [Transcription]; Region: COG1695
568704005530	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
568704005531	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
568704005532	dimer interface [polypeptide binding]; other site
568704005533	FMN binding site [chemical binding]; other site
568704005534	NADPH bind site [chemical binding]; other site
568704005535	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
568704005536	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
568704005537	Walker A/P-loop; other site
568704005538	ATP binding site [chemical binding]; other site
568704005539	Q-loop/lid; other site
568704005540	ABC transporter signature motif; other site
568704005541	Walker B; other site
568704005542	D-loop; other site
568704005543	H-loop/switch region; other site
568704005544	Putative exporter of polyketide antibiotics [Cell envelope biogenesis, outer membrane]; Region: TnrB3; COG3559
568704005545	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
568704005546	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
568704005547	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704005548	Major Facilitator Superfamily; Region: MFS_1; pfam07690
568704005549	putative substrate translocation pore; other site
568704005550	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704005551	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
568704005552	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
568704005553	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568704005554	non-specific DNA binding site [nucleotide binding]; other site
568704005555	salt bridge; other site
568704005556	sequence-specific DNA binding site [nucleotide binding]; other site
568704005557	Alpha/beta hydrolase of unknown function (DUF915); Region: DUF915; pfam06028
568704005558	Predicted transcriptional regulators [Transcription]; Region: COG1725
568704005559	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568704005560	DNA-binding site [nucleotide binding]; DNA binding site
568704005561	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
568704005562	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704005563	Walker A/P-loop; other site
568704005564	ATP binding site [chemical binding]; other site
568704005565	Q-loop/lid; other site
568704005566	ABC transporter signature motif; other site
568704005567	Walker B; other site
568704005568	D-loop; other site
568704005569	H-loop/switch region; other site
568704005570	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
568704005571	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
568704005572	Walker A/P-loop; other site
568704005573	ATP binding site [chemical binding]; other site
568704005574	Q-loop/lid; other site
568704005575	ABC transporter signature motif; other site
568704005576	Walker B; other site
568704005577	D-loop; other site
568704005578	H-loop/switch region; other site
568704005579	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
568704005580	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
568704005581	Walker A/P-loop; other site
568704005582	ATP binding site [chemical binding]; other site
568704005583	Q-loop/lid; other site
568704005584	ABC transporter signature motif; other site
568704005585	Walker B; other site
568704005586	D-loop; other site
568704005587	H-loop/switch region; other site
568704005588	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
568704005589	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
568704005590	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
568704005591	Walker A/P-loop; other site
568704005592	ATP binding site [chemical binding]; other site
568704005593	Q-loop/lid; other site
568704005594	ABC transporter signature motif; other site
568704005595	Walker B; other site
568704005596	D-loop; other site
568704005597	H-loop/switch region; other site
568704005598	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
568704005599	nickel ABC transporter, permease subunit NikC; Region: nickel_nikC; TIGR02790
568704005600	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568704005601	dimer interface [polypeptide binding]; other site
568704005602	conserved gate region; other site
568704005603	putative PBP binding loops; other site
568704005604	ABC-ATPase subunit interface; other site
568704005605	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
568704005606	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568704005607	dimer interface [polypeptide binding]; other site
568704005608	conserved gate region; other site
568704005609	putative PBP binding loops; other site
568704005610	ABC-ATPase subunit interface; other site
568704005611	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
568704005612	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
568704005613	peptide binding site [polypeptide binding]; other site
568704005614	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06676
568704005615	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
568704005616	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
568704005617	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704005618	Walker A/P-loop; other site
568704005619	ATP binding site [chemical binding]; other site
568704005620	Q-loop/lid; other site
568704005621	ABC transporter signature motif; other site
568704005622	Walker B; other site
568704005623	D-loop; other site
568704005624	H-loop/switch region; other site
568704005625	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
568704005626	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
568704005627	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
568704005628	Walker A/P-loop; other site
568704005629	ATP binding site [chemical binding]; other site
568704005630	Q-loop/lid; other site
568704005631	ABC transporter signature motif; other site
568704005632	Walker B; other site
568704005633	D-loop; other site
568704005634	H-loop/switch region; other site
568704005635	Phosphotransferase enzyme family; Region: APH; pfam01636
568704005636	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
568704005637	substrate binding site [chemical binding]; other site
568704005638	Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which...; Region: ZnMc; cl00064
568704005639	active site
568704005640	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568704005641	non-specific DNA binding site [nucleotide binding]; other site
568704005642	salt bridge; other site
568704005643	sequence-specific DNA binding site [nucleotide binding]; other site
568704005644	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
568704005645	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
568704005646	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568704005647	non-specific DNA binding site [nucleotide binding]; other site
568704005648	salt bridge; other site
568704005649	sequence-specific DNA binding site [nucleotide binding]; other site
568704005650	Mrr N-terminal domain; Region: Mrr_N; pfam14338
568704005651	Restriction endonuclease; Region: Mrr_cat; pfam04471
568704005652	Plasmid pRiA4b ORF-3-like protein; Region: PRiA4_ORF3; pfam07929
568704005653	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568704005654	non-specific DNA binding site [nucleotide binding]; other site
568704005655	salt bridge; other site
568704005656	sequence-specific DNA binding site [nucleotide binding]; other site
568704005657	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
568704005658	Divergent AAA domain; Region: AAA_4; pfam04326
568704005659	Abortive infection C-terminus; Region: Abi_C; pfam14355
568704005660	GMP synthase; Reviewed; Region: guaA; PRK00074
568704005661	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
568704005662	AMP/PPi binding site [chemical binding]; other site
568704005663	candidate oxyanion hole; other site
568704005664	catalytic triad [active]
568704005665	potential glutamine specificity residues [chemical binding]; other site
568704005666	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
568704005667	ATP Binding subdomain [chemical binding]; other site
568704005668	Dimerization subdomain; other site
568704005669	pantothenate kinase; Provisional; Region: PRK05439
568704005670	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
568704005671	ATP-binding site [chemical binding]; other site
568704005672	CoA-binding site [chemical binding]; other site
568704005673	Mg2+-binding site [ion binding]; other site
568704005674	Peptidase family C69; Region: Peptidase_C69; pfam03577
568704005675	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
568704005676	Superfamily I DNA and RNA helicases [General function prediction only]; Region: COG3973
568704005677	Part of AAA domain; Region: AAA_19; pfam13245
568704005678	Family description; Region: UvrD_C_2; pfam13538
568704005679	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
568704005680	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
568704005681	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
568704005682	TrkA-C domain; Region: TrkA_C; pfam02080
568704005683	proline-specific peptidase, Bacillus coagulans-type subfamily; Region: pro_imino_pep_2; TIGR01250
568704005684	manganese transport protein MntH; Reviewed; Region: PRK00701
568704005685	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
568704005686	Ferrochelatase; Region: Ferrochelatase; pfam00762
568704005687	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
568704005688	C-terminal domain interface [polypeptide binding]; other site
568704005689	active site
568704005690	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
568704005691	active site
568704005692	N-terminal domain interface [polypeptide binding]; other site
568704005693	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
568704005694	catalytic core [active]
568704005695	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
568704005696	rhamnulose-1-phosphate aldolase; Provisional; Region: PRK03634
568704005697	intersubunit interface [polypeptide binding]; other site
568704005698	active site
568704005699	Zn2+ binding site [ion binding]; other site
568704005700	FtsX-like permease family; Region: FtsX; pfam02687
568704005701	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704005702	ABC transporter signature motif; other site
568704005703	Walker B; other site
568704005704	D-loop; other site
568704005705	H-loop/switch region; other site
568704005706	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
568704005707	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704005708	Walker A/P-loop; other site
568704005709	ATP binding site [chemical binding]; other site
568704005710	Q-loop/lid; other site
568704005711	Amino acid permease; Region: AA_permease_2; pfam13520
568704005712	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
568704005713	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
568704005714	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
568704005715	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
568704005716	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
568704005717	HflX GTPase family; Region: HflX; cd01878
568704005718	G1 box; other site
568704005719	GTP/Mg2+ binding site [chemical binding]; other site
568704005720	Switch I region; other site
568704005721	G2 box; other site
568704005722	G3 box; other site
568704005723	Switch II region; other site
568704005724	G4 box; other site
568704005725	G5 box; other site
568704005726	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
568704005727	Catalytic NodB homology domain of Streptococcus mutans polysaccharide deacetylase PgdA, Bacillus subtilis YheN, and similar proteins; Region: CE4_SmPgdA_like; cd10944
568704005728	NodB motif; other site
568704005729	active site
568704005730	catalytic site [active]
568704005731	Zn binding site [ion binding]; other site
568704005732	NADH-ubiquinone/plastoquinone oxidoreductase chain 6; Region: Oxidored_q3; pfam00499
568704005733	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
568704005734	Sulfatase; Region: Sulfatase; cl17466
568704005735	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
568704005736	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
568704005737	Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane]; Region: COG3944
568704005738	Chain length determinant protein; Region: Wzz; cl15801
568704005739	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
568704005740	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
568704005741	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
568704005742	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
568704005743	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
568704005744	active site
568704005745	Domain of unknown function (DUF3367); Region: DUF3367; pfam11847
568704005746	AtlA is an autolysin found in Gram-positive lactic acid bacteria that degrades bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues. This family includes the AtlA and Aml...; Region: GH25_AtlA-like; cd06522
568704005747	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
568704005748	active site
568704005749	SH3-like domain; Region: SH3_8; pfam13457
568704005750	SH3-like domain; Region: SH3_8; pfam13457
568704005751	SH3-like domain; Region: SH3_8; pfam13457
568704005752	SH3-like domain; Region: SH3_8; pfam13457
568704005753	Acyltransferase family; Region: Acyl_transf_3; pfam01757
568704005754	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
568704005755	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
568704005756	Ligand binding site; other site
568704005757	Putative Catalytic site; other site
568704005758	DXD motif; other site
568704005759	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
568704005760	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
568704005761	active site
568704005762	homodimer interface [polypeptide binding]; other site
568704005763	exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025
568704005764	Bacterial sugar transferase; Region: Bac_transf; pfam02397
568704005765	Glycosyltransferase sugar-binding region containing DXD motif; Region: Gly_transf_sug; pfam04488
568704005766	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
568704005767	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
568704005768	active site
568704005769	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
568704005770	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
568704005771	NAD(P) binding site [chemical binding]; other site
568704005772	active site
568704005773	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
568704005774	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568704005775	dimer interface [polypeptide binding]; other site
568704005776	conserved gate region; other site
568704005777	putative PBP binding loops; other site
568704005778	ABC-ATPase subunit interface; other site
568704005779	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
568704005780	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568704005781	dimer interface [polypeptide binding]; other site
568704005782	conserved gate region; other site
568704005783	putative PBP binding loops; other site
568704005784	ABC-ATPase subunit interface; other site
568704005785	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
568704005786	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
568704005787	substrate binding pocket [chemical binding]; other site
568704005788	membrane-bound complex binding site; other site
568704005789	hinge residues; other site
568704005790	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
568704005791	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
568704005792	Walker A/P-loop; other site
568704005793	ATP binding site [chemical binding]; other site
568704005794	Q-loop/lid; other site
568704005795	ABC transporter signature motif; other site
568704005796	Walker B; other site
568704005797	D-loop; other site
568704005798	H-loop/switch region; other site
568704005799	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
568704005800	metal binding site 2 [ion binding]; metal-binding site
568704005801	putative DNA binding helix; other site
568704005802	metal binding site 1 [ion binding]; metal-binding site
568704005803	dimer interface [polypeptide binding]; other site
568704005804	structural Zn2+ binding site [ion binding]; other site
568704005805	Guanylate kinase; Region: Guanylate_kin; pfam00625
568704005806	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
568704005807	catalytic site [active]
568704005808	G-X2-G-X-G-K; other site
568704005809	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
568704005810	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568704005811	Coenzyme A binding pocket [chemical binding]; other site
568704005812	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
568704005813	NlpC/P60 family; Region: NLPC_P60; pfam00877
568704005814	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883
568704005815	tyrosyl-tRNA synthetase; Provisional; Region: PRK13354
568704005816	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
568704005817	active site
568704005818	HIGH motif; other site
568704005819	dimer interface [polypeptide binding]; other site
568704005820	KMSKS motif; other site
568704005821	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
568704005822	RNA binding surface [nucleotide binding]; other site
568704005823	Cation efflux family; Region: Cation_efflux; pfam01545
568704005824	Cation efflux family; Region: Cation_efflux; cl00316
568704005825	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
568704005826	dimerization interface [polypeptide binding]; other site
568704005827	putative DNA binding site [nucleotide binding]; other site
568704005828	putative Zn2+ binding site [ion binding]; other site
568704005829	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
568704005830	ApbE family; Region: ApbE; pfam02424
568704005831	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
568704005832	active site
568704005833	homodimer interface [polypeptide binding]; other site
568704005834	catalytic site [active]
568704005835	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
568704005836	homodimer interface [polypeptide binding]; other site
568704005837	glycogen/starch/alpha-glucan phosphorylases; Region: P_ylase; TIGR02093
568704005838	active site pocket [active]
568704005839	glycogen synthase; Provisional; Region: glgA; PRK00654
568704005840	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
568704005841	ADP-binding pocket [chemical binding]; other site
568704005842	homodimer interface [polypeptide binding]; other site
568704005843	glucose-1-phosphate adenylyltransferase, GlgD subunit; Region: glgD; TIGR02092
568704005844	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
568704005845	active site
568704005846	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
568704005847	dimer interface [polypeptide binding]; other site
568704005848	N-terminal domain interface [polypeptide binding]; other site
568704005849	sulfate 1 binding site; other site
568704005850	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK05293
568704005851	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
568704005852	ligand binding site; other site
568704005853	oligomer interface; other site
568704005854	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
568704005855	dimer interface [polypeptide binding]; other site
568704005856	N-terminal domain interface [polypeptide binding]; other site
568704005857	sulfate 1 binding site; other site
568704005858	glycogen branching enzyme; Provisional; Region: PRK12313
568704005859	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
568704005860	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
568704005861	active site
568704005862	catalytic site [active]
568704005863	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
568704005864	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
568704005865	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
568704005866	homodimer interface [polypeptide binding]; other site
568704005867	substrate-cofactor binding pocket; other site
568704005868	catalytic residue [active]
568704005869	Sortase family; Region: Sortase; pfam04203
568704005870	Uncharacterized conserved protein [Function unknown]; Region: COG1284
568704005871	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
568704005872	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
568704005873	Firmicute fructose-1,6-bisphosphatase; Region: FBPase_2; pfam06874
568704005874	Arsenate Reductase (ArsC) family, Spx subfamily; Spx is a unique RNA polymerase (RNAP)-binding protein present in bacilli and some mollicutes. It inhibits transcription by binding to the C-terminal domain of the alpha subunit of RNAP, disrupting complex...; Region: ArsC_Spx; cd03032
568704005875	ArsC family; Region: ArsC; pfam03960
568704005876	putative catalytic residues [active]
568704005877	thiol/disulfide switch; other site
568704005878	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568704005879	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
568704005880	Walker A motif; other site
568704005881	ATP binding site [chemical binding]; other site
568704005882	Walker B motif; other site
568704005883	arginine finger; other site
568704005884	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568704005885	Walker A motif; other site
568704005886	ATP binding site [chemical binding]; other site
568704005887	Walker B motif; other site
568704005888	arginine finger; other site
568704005889	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
568704005890	Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: CapC; COG4464
568704005891	Cell envelope-related transcriptional attenuator domain; Region: LytR_cpsA_psr; cl00581
568704005892	Bacterial sugar transferase; Region: Bac_transf; pfam02397
568704005893	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
568704005894	RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321
568704005895	NADP binding site [chemical binding]; other site
568704005896	active site
568704005897	putative substrate binding site [chemical binding]; other site
568704005898	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
568704005899	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
568704005900	NAD binding site [chemical binding]; other site
568704005901	substrate binding site [chemical binding]; other site
568704005902	homodimer interface [polypeptide binding]; other site
568704005903	active site
568704005904	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
568704005905	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
568704005906	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
568704005907	substrate binding site; other site
568704005908	tetramer interface; other site
568704005909	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; pfam04230
568704005910	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
568704005911	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
568704005912	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
568704005913	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_d; cd04196
568704005914	Probable Catalytic site; other site
568704005915	RfbF is a putative dTDP-rhamnosyl transferase; Region: GT2_RfbF_like; cd02526
568704005916	L-rhamnosyltransferase; Region: rhamnosyltran; TIGR01556
568704005917	Ligand binding site; other site
568704005918	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
568704005919	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
568704005920	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
568704005921	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
568704005922	active site
568704005923	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
568704005924	Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128
568704005925	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
568704005926	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
568704005927	Chain length determinant protein; Region: Wzz; cl15801
568704005928	yrhL-like subfamily of SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_yrhL_like; cd01840
568704005929	catalytic triad [active]
568704005930	catalytic triad [active]
568704005931	oxyanion hole [active]
568704005932	QueT transporter; Region: QueT; pfam06177
568704005933	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK06550
568704005934	classical (c) SDRs; Region: SDR_c; cd05233
568704005935	NAD(P) binding site [chemical binding]; other site
568704005936	active site
568704005937	Protein of unknown function (DUF2829); Region: DUF2829; pfam11195
568704005938	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
568704005939	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568704005940	non-specific DNA binding site [nucleotide binding]; other site
568704005941	salt bridge; other site
568704005942	sequence-specific DNA binding site [nucleotide binding]; other site
568704005943	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
568704005944	catalytic core [active]
568704005945	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
568704005946	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
568704005947	Walker A/P-loop; other site
568704005948	ATP binding site [chemical binding]; other site
568704005949	Q-loop/lid; other site
568704005950	ABC transporter signature motif; other site
568704005951	Walker B; other site
568704005952	D-loop; other site
568704005953	H-loop/switch region; other site
568704005954	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
568704005955	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
568704005956	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
568704005957	Walker A/P-loop; other site
568704005958	ATP binding site [chemical binding]; other site
568704005959	Q-loop/lid; other site
568704005960	ABC transporter signature motif; other site
568704005961	Walker B; other site
568704005962	D-loop; other site
568704005963	H-loop/switch region; other site
568704005964	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
568704005965	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
568704005966	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
568704005967	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568704005968	dimer interface [polypeptide binding]; other site
568704005969	conserved gate region; other site
568704005970	putative PBP binding loops; other site
568704005971	ABC-ATPase subunit interface; other site
568704005972	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
568704005973	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568704005974	dimer interface [polypeptide binding]; other site
568704005975	conserved gate region; other site
568704005976	putative PBP binding loops; other site
568704005977	ABC-ATPase subunit interface; other site
568704005978	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
568704005979	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
568704005980	peptide binding site [polypeptide binding]; other site
568704005981	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704005982	Major Facilitator Superfamily; Region: MFS_1; pfam07690
568704005983	putative substrate translocation pore; other site
568704005984	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704005985	elongation factor P; Validated; Region: PRK00529
568704005986	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
568704005987	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
568704005988	RNA binding site [nucleotide binding]; other site
568704005989	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
568704005990	RNA binding site [nucleotide binding]; other site
568704005991	Uncharacterized conserved protein [Function unknown]; Region: COG1556
568704005992	Uncharacterized conserved protein containing a ferredoxin-like domain [Energy production and conversion]; Region: COG1139
568704005993	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
568704005994	4Fe-4S binding domain; Region: Fer4; pfam00037
568704005995	CoB--CoM heterodisulfide reductase, subunit B; Region: CoB_CoM_SS_B; TIGR03288
568704005996	Cysteine-rich domain; Region: CCG; pfam02754
568704005997	Cysteine-rich domain; Region: CCG; pfam02754
568704005998	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
568704005999	active site
568704006000	methionine cluster; other site
568704006001	phosphorylation site [posttranslational modification]
568704006002	metal binding site [ion binding]; metal-binding site
568704006003	Uncharacterized conserved protein [Function unknown]; Region: COG3589
568704006004	Bacterial protein of unknown function (DUF871); Region: DUF871; pfam05913
568704006005	Domain of unknown function (DUF3284); Region: DUF3284; pfam11687
568704006006	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
568704006007	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
568704006008	Alpha-galactosidase [Carbohydrate transport and metabolism]; Region: GalA; COG3345
568704006009	Melibiase; Region: Melibiase; pfam02065
568704006010	hypothetical protein; Validated; Region: PRK02101
568704006011	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
568704006012	DNA binding residues [nucleotide binding]
568704006013	Winged helix-turn helix; Region: HTH_29; pfam13551
568704006014	Uncharacterized protein conserved in bacteria (DUF2087); Region: DUF2087; pfam09860
568704006015	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
568704006016	AAA domain; Region: AAA_30; pfam13604
568704006017	WxL domain surface cell wall-binding; Region: WxL; pfam13731
568704006018	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
568704006019	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
568704006020	substrate binding site [chemical binding]; other site
568704006021	ATP binding site [chemical binding]; other site
568704006022	Predicted periplasmic protein [Function unknown]; Region: COG3698
568704006023	Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992
568704006024	N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuA; COG0145
568704006025	Hydantoinase/oxoprolinase N-terminal region; Region: Hydant_A_N; pfam05378
568704006026	Hydantoinase/oxoprolinase; Region: Hydantoinase_A; pfam01968
568704006027	Uncharacterized conserved protein [Function unknown]; Region: COG3535
568704006028	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
568704006029	Na binding site [ion binding]; other site
568704006030	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
568704006031	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
568704006032	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
568704006033	Int/Topo IB signature motif; other site
568704006034	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
568704006035	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
568704006036	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
568704006037	HsdM N-terminal domain; Region: HsdM_N; pfam12161
568704006038	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
568704006039	Methyltransferase domain; Region: Methyltransf_26; pfam13659
568704006040	type I site-specific deoxyribonuclease, HsdR family; Region: hsdR; TIGR00348
568704006041	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
568704006042	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
568704006043	ATP binding site [chemical binding]; other site
568704006044	putative Mg++ binding site [ion binding]; other site
568704006045	Type I restriction and modification enzyme - subunit R C terminal; Region: EcoR124_C; pfam12008
568704006046	looped-hinge helix DNA binding domain, AbrB family; Region: lp_hng_hel_AbrB; TIGR01439
568704006047	Protein of unknown function (DUF998); Region: DUF998; pfam06197
568704006048	YhgE/Pip C-terminal domain; Region: pip_yhgE_Cterm; TIGR03062
568704006049	Predicted membrane protein [Function unknown]; Region: COG1511
568704006050	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
568704006051	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
568704006052	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
568704006053	HPr interaction site; other site
568704006054	glycerol kinase (GK) interaction site [polypeptide binding]; other site
568704006055	active site
568704006056	phosphorylation site [posttranslational modification]
568704006057	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
568704006058	active site turn [active]
568704006059	phosphorylation site [posttranslational modification]
568704006060	PTS system, glucose-like IIB component; Region: EIIB_glc; TIGR00826
568704006061	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
568704006062	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
568704006063	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
568704006064	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
568704006065	Ca binding site [ion binding]; other site
568704006066	active site
568704006067	catalytic site [active]
568704006068	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
568704006069	Transcriptional regulators [Transcription]; Region: PurR; COG1609
568704006070	Transcriptional regulators [Transcription]; Region: PurR; COG1609
568704006071	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
568704006072	DNA binding site [nucleotide binding]
568704006073	domain linker motif; other site
568704006074	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
568704006075	sucrose-6-phosphate hydrolase; Region: scrB_fam; TIGR01322
568704006076	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
568704006077	substrate binding [chemical binding]; other site
568704006078	active site
568704006079	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
568704006080	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
568704006081	NmrA-like family; Region: NmrA; pfam05368
568704006082	NADP binding site [chemical binding]; other site
568704006083	Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane]; Region: Cfa; COG2230
568704006084	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568704006085	S-adenosylmethionine binding site [chemical binding]; other site
568704006086	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
568704006087	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
568704006088	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
568704006089	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
568704006090	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
568704006091	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
568704006092	ATP-grasp domain; Region: ATP-grasp_4; cl17255
568704006093	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
568704006094	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
568704006095	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
568704006096	carboxyltransferase (CT) interaction site; other site
568704006097	biotinylation site [posttranslational modification]; other site
568704006098	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
568704006099	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
568704006100	dimer interface [polypeptide binding]; other site
568704006101	active site
568704006102	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
568704006103	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
568704006104	NAD(P) binding site [chemical binding]; other site
568704006105	homotetramer interface [polypeptide binding]; other site
568704006106	homodimer interface [polypeptide binding]; other site
568704006107	active site
568704006108	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
568704006109	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
568704006110	putative enoyl-[acyl-carrier-protein] reductase II; Region: enACPred_II; TIGR03151
568704006111	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
568704006112	FMN binding site [chemical binding]; other site
568704006113	substrate binding site [chemical binding]; other site
568704006114	putative catalytic residue [active]
568704006115	acyl carrier protein; Provisional; Region: acpP; PRK00982
568704006116	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
568704006117	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
568704006118	dimer interface [polypeptide binding]; other site
568704006119	active site
568704006120	CoA binding pocket [chemical binding]; other site
568704006121	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
568704006122	MarR family; Region: MarR_2; pfam12802
568704006123	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
568704006124	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
568704006125	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
568704006126	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
568704006127	dimer interface [polypeptide binding]; other site
568704006128	active site
568704006129	metal binding site [ion binding]; metal-binding site
568704006130	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
568704006131	active site residue [active]
568704006132	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
568704006133	MarR family; Region: MarR_2; pfam12802
568704006134	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
568704006135	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
568704006136	I-site; other site
568704006137	Bacterial cellulose synthase subunit; Region: BcsB; cl15851
568704006138	Bacterial cellulose synthase subunit; Region: BcsB; cl15851
568704006139	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
568704006140	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
568704006141	DXD motif; other site
568704006142	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
568704006143	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
568704006144	metal binding site [ion binding]; metal-binding site
568704006145	active site
568704006146	I-site; other site
568704006147	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
568704006148	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
568704006149	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
568704006150	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
568704006151	MarR family; Region: MarR_2; pfam12802
568704006152	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
568704006153	Double zinc ribbon; Region: DZR; pfam12773
568704006154	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
568704006155	Predicted esterase [General function prediction only]; Region: COG0627
568704006156	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
568704006157	Double zinc ribbon; Region: DZR; pfam12773
568704006158	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
568704006159	putative Zn2+ binding site [ion binding]; other site
568704006160	putative DNA binding site [nucleotide binding]; other site
568704006161	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_18; cd04677
568704006162	nudix motif; other site
568704006163	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
568704006164	catalytic core [active]
568704006165	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
568704006166	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
568704006167	Double zinc ribbon; Region: DZR; pfam12773
568704006168	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
568704006169	Beta-lactamase; Region: Beta-lactamase; pfam00144
568704006170	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
568704006171	Sortase A (SrtA) or subfamily-1 sortases are cysteine transpeptidases found in gram-positive bacteria that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. They do so by catalyzing a transpeptidation reaction in which the...; Region: Sortase_A_1; cd06165
568704006172	active site
568704006173	catalytic site [active]
568704006174	Predicted membrane protein [Function unknown]; Region: COG2246
568704006175	GtrA-like protein; Region: GtrA; pfam04138
568704006176	pyruvate oxidase; Region: pyruv_oxi_spxB; TIGR02720
568704006177	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
568704006178	PYR/PP interface [polypeptide binding]; other site
568704006179	tetramer interface [polypeptide binding]; other site
568704006180	dimer interface [polypeptide binding]; other site
568704006181	TPP binding site [chemical binding]; other site
568704006182	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
568704006183	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
568704006184	TPP-binding site [chemical binding]; other site
568704006185	ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; cl17891
568704006186	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
568704006187	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
568704006188	glycine betaine transporter membrane protein; Provisional; Region: PRK10952
568704006189	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568704006190	dimer interface [polypeptide binding]; other site
568704006191	conserved gate region; other site
568704006192	putative PBP binding loops; other site
568704006193	ABC-ATPase subunit interface; other site
568704006194	ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism]; Region: ProV; COG4175
568704006195	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
568704006196	Walker A/P-loop; other site
568704006197	ATP binding site [chemical binding]; other site
568704006198	Q-loop/lid; other site
568704006199	ABC transporter signature motif; other site
568704006200	Walker B; other site
568704006201	D-loop; other site
568704006202	H-loop/switch region; other site
568704006203	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
568704006204	Sugar fermentation stimulation protein; Region: SfsA; cl00647
568704006205	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
568704006206	Ligand Binding Site [chemical binding]; other site
568704006207	Predicted ATP-grasp enzyme [General function prediction only]; Region: COG3919
568704006208	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
568704006209	homoserine kinase; Provisional; Region: PRK01212
568704006210	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
568704006211	threonine synthase; Validated; Region: PRK09225
568704006212	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
568704006213	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
568704006214	catalytic residue [active]
568704006215	Homoserine dehydrogenase [Amino acid transport and metabolism]; Region: ThrA; COG0460
568704006216	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
568704006217	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
568704006218	aspartate kinase; Reviewed; Region: PRK09034
568704006219	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
568704006220	nucleotide binding site [chemical binding]; other site
568704006221	substrate binding site [chemical binding]; other site
568704006222	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
568704006223	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
568704006224	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
568704006225	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
568704006226	Predicted membrane protein, putative toxin regulator [General function prediction only]; Region: PfoR; COG3641
568704006227	Phosphotransferase system, EIIC; Region: PTS_EIIC_2; pfam13303
568704006228	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
568704006229	D-Lactate dehydrogenase and D-2-Hydroxyisocaproic acid dehydrogenase (D-HicDH), NAD-binding and catalytic domains; Region: LDH; cd12186
568704006230	homodimer interface [polypeptide binding]; other site
568704006231	ligand binding site [chemical binding]; other site
568704006232	NAD binding site [chemical binding]; other site
568704006233	catalytic site [active]
568704006234	aromatic amino acid aminotransferase; Validated; Region: PRK07309
568704006235	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
568704006236	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568704006237	homodimer interface [polypeptide binding]; other site
568704006238	catalytic residue [active]
568704006239	Uncharacterized conserved protein [Function unknown]; Region: COG2013
568704006240	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
568704006241	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
568704006242	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
568704006243	Transcriptional regulator C-terminal region; Region: TetR_C_8; pfam14278
568704006244	Predicted membrane protein [Function unknown]; Region: COG1511
568704006245	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
568704006246	YhgE/Pip C-terminal domain; Region: pip_yhgE_Cterm; TIGR03062
568704006247	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
568704006248	Cation efflux family; Region: Cation_efflux; pfam01545
568704006249	Asparagine synthase (glutamine-hydrolyzing) [Amino acid transport and metabolism]; Region: AsnB; COG0367
568704006250	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
568704006251	active site
568704006252	dimer interface [polypeptide binding]; other site
568704006253	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
568704006254	Ligand Binding Site [chemical binding]; other site
568704006255	Molecular Tunnel; other site
568704006256	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
568704006257	active site
568704006258	metal binding site [ion binding]; metal-binding site
568704006259	1,4-dihydroxy-2-naphthoate octaprenyltransferase [Coenzyme metabolism]; Region: MenA; cl17224
568704006260	UbiA prenyltransferase family; Region: UbiA; pfam01040
568704006261	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
568704006262	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
568704006263	substrate binding pocket [chemical binding]; other site
568704006264	chain length determination region; other site
568704006265	substrate-Mg2+ binding site; other site
568704006266	catalytic residues [active]
568704006267	aspartate-rich region 1; other site
568704006268	active site lid residues [active]
568704006269	aspartate-rich region 2; other site
568704006270	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
568704006271	propionate/acetate kinase; Provisional; Region: PRK12379
568704006272	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4152
568704006273	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704006274	Walker A/P-loop; other site
568704006275	ATP binding site [chemical binding]; other site
568704006276	Q-loop/lid; other site
568704006277	ABC transporter signature motif; other site
568704006278	Walker B; other site
568704006279	D-loop; other site
568704006280	H-loop/switch region; other site
568704006281	Domain of unknown function (DUF4162); Region: DUF4162; pfam13732
568704006282	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
568704006283	Predicted transcriptional regulators [Transcription]; Region: COG1725
568704006284	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568704006285	DNA-binding site [nucleotide binding]; DNA binding site
568704006286	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
568704006287	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
568704006288	Walker A/P-loop; other site
568704006289	ATP binding site [chemical binding]; other site
568704006290	Q-loop/lid; other site
568704006291	ABC transporter signature motif; other site
568704006292	Walker B; other site
568704006293	D-loop; other site
568704006294	H-loop/switch region; other site
568704006295	glucose-1-dehydrogenase; Provisional; Region: PRK08936
568704006296	glucose 1 dehydrogenase (GlcDH), classical (c) SDRs; Region: GlcDH_SDR_c; cd05358
568704006297	NAD binding site [chemical binding]; other site
568704006298	homodimer interface [polypeptide binding]; other site
568704006299	active site
568704006300	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
568704006301	beta-galactosidase; Region: BGL; TIGR03356
568704006302	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
568704006303	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
568704006304	active site turn [active]
568704006305	phosphorylation site [posttranslational modification]
568704006306	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
568704006307	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
568704006308	HPr interaction site; other site
568704006309	glycerol kinase (GK) interaction site [polypeptide binding]; other site
568704006310	active site
568704006311	phosphorylation site [posttranslational modification]
568704006312	transcriptional antiterminator BglG; Provisional; Region: PRK09772
568704006313	CAT RNA binding domain; Region: CAT_RBD; smart01061
568704006314	PRD domain; Region: PRD; pfam00874
568704006315	PRD domain; Region: PRD; pfam00874
568704006316	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
568704006317	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
568704006318	Walker A/P-loop; other site
568704006319	ATP binding site [chemical binding]; other site
568704006320	Q-loop/lid; other site
568704006321	ABC transporter signature motif; other site
568704006322	Walker B; other site
568704006323	D-loop; other site
568704006324	H-loop/switch region; other site
568704006325	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
568704006326	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
568704006327	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydD; COG4988
568704006328	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
568704006329	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704006330	Walker A/P-loop; other site
568704006331	ATP binding site [chemical binding]; other site
568704006332	Q-loop/lid; other site
568704006333	ABC transporter signature motif; other site
568704006334	Walker B; other site
568704006335	D-loop; other site
568704006336	H-loop/switch region; other site
568704006337	Listerrria innocua Lin0431  is similar to the N-Utilization Substance G (NusG) N terminal (NGN) insert (DII); Region: Lin0431_like; cd09911
568704006338	trimer interface [polypeptide binding]; other site
568704006339	ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydC; COG4987
568704006340	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
568704006341	ATP-binding cassette domain of CydCD, subfamily C; Region: ABCC_cytochrome_bd; cd03247
568704006342	Walker A/P-loop; other site
568704006343	ATP binding site [chemical binding]; other site
568704006344	Q-loop/lid; other site
568704006345	ABC transporter signature motif; other site
568704006346	Walker B; other site
568704006347	D-loop; other site
568704006348	H-loop/switch region; other site
568704006349	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydD; COG4988
568704006350	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
568704006351	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704006352	Walker A/P-loop; other site
568704006353	ATP binding site [chemical binding]; other site
568704006354	Q-loop/lid; other site
568704006355	ABC transporter signature motif; other site
568704006356	Walker B; other site
568704006357	D-loop; other site
568704006358	H-loop/switch region; other site
568704006359	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
568704006360	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
568704006361	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
568704006362	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
568704006363	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
568704006364	pyrimidine-nucleoside phosphorylase; Region: Y_phosphoryl; TIGR02644
568704006365	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
568704006366	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; smart00941
568704006367	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
568704006368	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
568704006369	active site
568704006370	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
568704006371	EamA-like transporter family; Region: EamA; pfam00892
568704006372	EamA-like transporter family; Region: EamA; pfam00892
568704006373	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
568704006374	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
568704006375	Ligand Binding Site [chemical binding]; other site
568704006376	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
568704006377	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568704006378	non-specific DNA binding site [nucleotide binding]; other site
568704006379	salt bridge; other site
568704006380	sequence-specific DNA binding site [nucleotide binding]; other site
568704006381	Tyrosine phosphatase family; Region: Y_phosphatase3; pfam13350
568704006382	Tyrosine phosphatase family C-terminal region; Region: Y_phosphatase3C; pfam13348
568704006383	epoxyqueuosine reductase; Region: TIGR00276
568704006384	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
568704006385	Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; Region: ARM; cl02500
568704006386	protein binding surface [polypeptide binding]; other site
568704006387	BioY family; Region: BioY; pfam02632
568704006388	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568704006389	S-adenosylmethionine binding site [chemical binding]; other site
568704006390	GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518
568704006391	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
568704006392	catalytic triad [active]
568704006393	Uncharacterized protein conserved in bacteria (DUF2263); Region: DUF2263; pfam10021
568704006394	Macro domain, a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Some macro domains recognize poly...; Region: Macro; cl00019
568704006395	Domain of unknown function DUF21; Region: DUF21; pfam01595
568704006396	FOG: CBS domain [General function prediction only]; Region: COG0517
568704006397	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
568704006398	Transporter associated domain; Region: CorC_HlyC; smart01091
568704006399	Alpha/beta hydrolase of unknown function (DUF915); Region: DUF915; pfam06028
568704006400	Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism]; Region: NolL; COG3594
568704006401	Acyltransferase family; Region: Acyl_transf_3; pfam01757
568704006402	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704006403	Major Facilitator Superfamily; Region: MFS_1; pfam07690
568704006404	Maf-like protein; Region: Maf; pfam02545
568704006405	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
568704006406	active site
568704006407	dimer interface [polypeptide binding]; other site
568704006408	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
568704006409	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568704006410	ATP binding site [chemical binding]; other site
568704006411	Mg2+ binding site [ion binding]; other site
568704006412	G-X-G motif; other site
568704006413	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
568704006414	ATP binding site [chemical binding]; other site
568704006415	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
568704006416	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
568704006417	MutS domain I; Region: MutS_I; pfam01624
568704006418	MutS domain II; Region: MutS_II; pfam05188
568704006419	MutS domain III; Region: MutS_III; pfam05192
568704006420	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
568704006421	Walker A/P-loop; other site
568704006422	ATP binding site [chemical binding]; other site
568704006423	Q-loop/lid; other site
568704006424	ABC transporter signature motif; other site
568704006425	Walker B; other site
568704006426	D-loop; other site
568704006427	H-loop/switch region; other site
568704006428	Amino acid permease; Region: AA_permease_2; pfam13520
568704006429	Domain of unknown function (DUF1827); Region: DUF1827; pfam08860
568704006430	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
568704006431	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
568704006432	ring oligomerisation interface [polypeptide binding]; other site
568704006433	ATP/Mg binding site [chemical binding]; other site
568704006434	stacking interactions; other site
568704006435	hinge regions; other site
568704006436	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
568704006437	oligomerisation interface [polypeptide binding]; other site
568704006438	mobile loop; other site
568704006439	roof hairpin; other site
568704006440	CAAX protease self-immunity; Region: Abi; pfam02517
568704006441	Cell envelope-related transcriptional attenuator domain; Region: LytR_cpsA_psr; cl00581
568704006442	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
568704006443	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
568704006444	Walker A/P-loop; other site
568704006445	ATP binding site [chemical binding]; other site
568704006446	Q-loop/lid; other site
568704006447	ABC transporter signature motif; other site
568704006448	Walker B; other site
568704006449	D-loop; other site
568704006450	H-loop/switch region; other site
568704006451	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568704006452	DNA-binding site [nucleotide binding]; DNA binding site
568704006453	redox-sensing transcriptional repressor Rex; Provisional; Region: PRK05472
568704006454	Putative DNA-binding protein N-terminus; Region: Put_DNA-bind_N; pfam06971
568704006455	CoA binding domain; Region: CoA_binding; pfam02629
568704006456	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
568704006457	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704006458	Walker A/P-loop; other site
568704006459	ATP binding site [chemical binding]; other site
568704006460	Q-loop/lid; other site
568704006461	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
568704006462	ABC transporter signature motif; other site
568704006463	Walker B; other site
568704006464	D-loop; other site
568704006465	ABC transporter; Region: ABC_tran_2; pfam12848
568704006466	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
568704006467	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
568704006468	active site
568704006469	P-loop; other site
568704006470	phosphorylation site [posttranslational modification]
568704006471	UGMP family protein; Validated; Region: PRK09604
568704006472	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
568704006473	Carbamoyltransferase; Region: CmcH_NodU; pfam02543
568704006474	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
568704006475	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568704006476	Coenzyme A binding pocket [chemical binding]; other site
568704006477	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
568704006478	Glycoprotease family; Region: Peptidase_M22; pfam00814
568704006479	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
568704006480	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
568704006481	active site
568704006482	homotetramer interface [polypeptide binding]; other site
568704006483	homodimer interface [polypeptide binding]; other site
568704006484	Acyl-ACP thioesterase; Region: Acyl-ACP_TE; pfam01643
568704006485	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
568704006486	active site
568704006487	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
568704006488	active site 2 [active]
568704006489	active site 1 [active]
568704006490	Predicted methyltransferases [General function prediction only]; Region: COG0313
568704006491	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
568704006492	putative SAM binding site [chemical binding]; other site
568704006493	putative homodimer interface [polypeptide binding]; other site
568704006494	Protein of unknown function (DUF972); Region: DUF972; pfam06156
568704006495	DNA polymerase III subunit delta'; Validated; Region: PRK08058
568704006496	DNA polymerase III subunit delta'; Validated; Region: PRK08485
568704006497	Protein of unknown function (DUF970); Region: DUF970; pfam06153
568704006498	thymidylate kinase; Validated; Region: tmk; PRK00698
568704006499	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
568704006500	TMP-binding site; other site
568704006501	ATP-binding site [chemical binding]; other site
568704006502	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
568704006503	active site
568704006504	Protein of unknown function (DUF2508); Region: DUF2508; pfam10704
568704006505	recombination protein RecR; Reviewed; Region: recR; PRK00076
568704006506	RecR protein; Region: RecR; pfam02132
568704006507	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
568704006508	putative active site [active]
568704006509	putative metal-binding site [ion binding]; other site
568704006510	tetramer interface [polypeptide binding]; other site
568704006511	hypothetical protein; Validated; Region: PRK00153
568704006512	DNA polymerase III subunits gamma and tau; Validated; Region: PRK05563
568704006513	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568704006514	Walker A motif; other site
568704006515	ATP binding site [chemical binding]; other site
568704006516	Walker B motif; other site
568704006517	arginine finger; other site
568704006518	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
568704006519	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
568704006520	nucleoside/Zn binding site; other site
568704006521	dimer interface [polypeptide binding]; other site
568704006522	catalytic motif [active]
568704006523	Methyltransferase domain; Region: Methyltransf_31; pfam13847
568704006524	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568704006525	S-adenosylmethionine binding site [chemical binding]; other site
568704006526	Uncharacterized conserved protein (DUF2156); Region: DUF2156; pfam09924
568704006527	Predicted integral membrane protein [Function unknown]; Region: COG0392
568704006528	Uncharacterized conserved protein [Function unknown]; Region: COG2898
568704006529	Uncharacterized conserved protein (DUF2156); Region: DUF2156; pfam09924
568704006530	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
568704006531	Probable transposase; Region: OrfB_IS605; pfam01385
568704006532	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
568704006533	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
568704006534	Transcriptional regulators [Transcription]; Region: PurR; COG1609
568704006535	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
568704006536	DNA binding site [nucleotide binding]
568704006537	domain linker motif; other site
568704006538	Ligand-binding domain of a novel transcription factor implicated in catabolite repression in Bacillus and Clostridium species; Region: PBP1_CcpB_like; cd06286
568704006539	putative dimerization interface [polypeptide binding]; other site
568704006540	putative ligand binding site [chemical binding]; other site
568704006541	Peptidase S8 family domain in Streptococcal C5a peptidases; Region: Peptidases_S8_C5a_Peptidase; cd07475
568704006542	putative active site [active]
568704006543	catalytic triad [active]
568704006544	Peptidase S8 family domain in Streptococcal C5a peptidases; Region: Peptidases_S8_C5a_Peptidase; cd07475
568704006545	putative active site [active]
568704006546	Fn3-like domain (DUF1034); Region: DUF1034; pfam06280
568704006547	peptidylprolyl isomerase; Provisional; Region: prsA; PRK04405
568704006548	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
568704006549	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
568704006550	core dimer interface [polypeptide binding]; other site
568704006551	peripheral dimer interface [polypeptide binding]; other site
568704006552	L10 interface [polypeptide binding]; other site
568704006553	L11 interface [polypeptide binding]; other site
568704006554	putative EF-Tu interaction site [polypeptide binding]; other site
568704006555	putative EF-G interaction site [polypeptide binding]; other site
568704006556	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
568704006557	23S rRNA interface [nucleotide binding]; other site
568704006558	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
568704006559	drug efflux system protein MdtG; Provisional; Region: PRK09874
568704006560	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704006561	putative substrate translocation pore; other site
568704006562	benzoate transport; Region: 2A0115; TIGR00895
568704006563	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704006564	putative substrate translocation pore; other site
568704006565	Domain of unknown function (DUF1975); Region: DUF1975; pfam09318
568704006566	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
568704006567	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
568704006568	Domain of unknown function (DUF1975); Region: DUF1975; pfam09318
568704006569	This family is most closely related to the GT1 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding.  In...; Region: GT1_gtfA_like; cd04949
568704006570	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
568704006571	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
568704006572	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
568704006573	NAD(P) binding site [chemical binding]; other site
568704006574	catalytic residues [active]
568704006575	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
568704006576	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568704006577	Coenzyme A binding pocket [chemical binding]; other site
568704006578	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
568704006579	mRNA/rRNA interface [nucleotide binding]; other site
568704006580	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
568704006581	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
568704006582	23S rRNA interface [nucleotide binding]; other site
568704006583	L7/L12 interface [polypeptide binding]; other site
568704006584	putative thiostrepton binding site; other site
568704006585	L25 interface [polypeptide binding]; other site
568704006586	magnesium-transporting ATPase; Provisional; Region: PRK15122
568704006587	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
568704006588	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
568704006589	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
568704006590	Soluble P-type ATPase [General function prediction only]; Region: COG4087
568704006591	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
568704006592	amidase; Provisional; Region: PRK06529
568704006593	Amidase; Region: Amidase; cl11426
568704006594	Cobalamin adenosyltransferase; Region: Cob_adeno_trans; pfam01923
568704006595	ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent; Region: RTPR; TIGR02505
568704006596	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
568704006597	Nucleoside 2-deoxyribosyltransferase; Region: Nuc_deoxyrib_tr; pfam05014
568704006598	Alpha/beta hydrolase of unknown function (DUF915); Region: DUF915; pfam06028
568704006599	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
568704006600	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
568704006601	putative homodimer interface [polypeptide binding]; other site
568704006602	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
568704006603	heterodimer interface [polypeptide binding]; other site
568704006604	homodimer interface [polypeptide binding]; other site
568704006605	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK07597
568704006606	50S ribosomal protein L33; Validated; Region: rpmG; PRK00504
568704006607	1,4-dihydroxy-2-naphthoate octaprenyltransferase [Coenzyme metabolism]; Region: MenA; cl17224
568704006608	1,4-dihydroxy-2-naphthoate octaprenyltransferase [Coenzyme metabolism]; Region: MenA; cl17224
568704006609	UbiA prenyltransferase family; Region: UbiA; pfam01040
568704006610	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
568704006611	ApbE family; Region: ApbE; pfam02424
568704006612	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
568704006613	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
568704006614	Probable transposase; Region: OrfB_IS605; pfam01385
568704006615	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
568704006616	This conserved region includes the FMN-binding site of the NqrC protein as well as the NosR and NirI regulatory proteins; Region: FMN_bind; smart00900
568704006617	This conserved region includes the FMN-binding site of the NqrC protein as well as the NosR and NirI regulatory proteins; Region: FMN_bind; smart00900
568704006618	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
568704006619	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
568704006620	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
568704006621	Listerrria innocua Lin0431  is similar to the N-Utilization Substance G (NusG) N terminal (NGN) insert (DII); Region: Lin0431_like; cd09911
568704006622	trimer interface [polypeptide binding]; other site
568704006623	Heptaprenyl diphosphate synthase component I; Region: Hpre_diP_synt_I; pfam07456
568704006624	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
568704006625	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
568704006626	substrate binding pocket [chemical binding]; other site
568704006627	chain length determination region; other site
568704006628	substrate-Mg2+ binding site; other site
568704006629	catalytic residues [active]
568704006630	aspartate-rich region 1; other site
568704006631	active site lid residues [active]
568704006632	aspartate-rich region 2; other site
568704006633	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
568704006634	Calcineurin-like phosphoesterase superfamily domain; Region: Metallophos_2; pfam12850
568704006635	active site
568704006636	metal binding site [ion binding]; metal-binding site
568704006637	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
568704006638	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
568704006639	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
568704006640	Walker A/P-loop; other site
568704006641	ATP binding site [chemical binding]; other site
568704006642	Q-loop/lid; other site
568704006643	ABC transporter signature motif; other site
568704006644	Walker B; other site
568704006645	D-loop; other site
568704006646	H-loop/switch region; other site
568704006647	probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858
568704006648	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Energy production and conversion]; Region: COG2141
568704006649	probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858
568704006650	YacP-like NYN domain; Region: NYN_YacP; pfam05991
568704006651	rRNA methylase, putative, group 3; Region: rRNA_methyl_3; TIGR00186
568704006652	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
568704006653	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
568704006654	Ribonuclease III family protein [Replication, recombination, and    repair]; Region: COG1939
568704006655	active site
568704006656	metal binding site [ion binding]; metal-binding site
568704006657	dimerization interface [polypeptide binding]; other site
568704006658	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
568704006659	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
568704006660	active site
568704006661	HIGH motif; other site
568704006662	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
568704006663	KMSKS motif; other site
568704006664	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
568704006665	tRNA binding surface [nucleotide binding]; other site
568704006666	anticodon binding site; other site
568704006667	FAD binding domain; Region: FAD_binding_4; pfam01565
568704006668	glycolate oxidase, subunit GlcD; Region: glcD; TIGR00387
568704006669	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
568704006670	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
568704006671	active site
568704006672	HIGH motif; other site
568704006673	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
568704006674	active site
568704006675	KMSKS motif; other site
568704006676	Putative membrane peptidase family (DUF2324); Region: DUF2324; pfam10086
568704006677	Predicted membrane protein [General function prediction only]; Region: COG4194
568704006678	Predicted transcriptional regulators [Transcription]; Region: COG1725
568704006679	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568704006680	DNA-binding site [nucleotide binding]; DNA binding site
568704006681	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
568704006682	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704006683	Walker A/P-loop; other site
568704006684	ATP binding site [chemical binding]; other site
568704006685	Q-loop/lid; other site
568704006686	ABC transporter signature motif; other site
568704006687	Walker B; other site
568704006688	D-loop; other site
568704006689	H-loop/switch region; other site
568704006690	KxYKxGKxW signal peptide; Region: KxYKxGKxW; TIGR03715
568704006691	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
568704006692	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
568704006693	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
568704006694	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
568704006695	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
568704006696	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
568704006697	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
568704006698	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704006699	Walker A/P-loop; other site
568704006700	ATP binding site [chemical binding]; other site
568704006701	Q-loop/lid; other site
568704006702	ABC transporter signature motif; other site
568704006703	Walker B; other site
568704006704	D-loop; other site
568704006705	H-loop/switch region; other site
568704006706	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
568704006707	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568704006708	non-specific DNA binding site [nucleotide binding]; other site
568704006709	salt bridge; other site
568704006710	sequence-specific DNA binding site [nucleotide binding]; other site
568704006711	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
568704006712	Integral membrane protein (PIN domain superfamily) [General function prediction only]; Region: COG4956
568704006713	PIN domain of Thermus Thermophilus Hb8, uncharacterized Bacillus subtilis YacL, and other bacterial homologs; Region: PIN_YacL; cd09877
568704006714	putative active site [active]
568704006715	DNA repair protein RadA; Provisional; Region: PRK11823
568704006716	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
568704006717	Walker A motif/ATP binding site; other site
568704006718	ATP binding site [chemical binding]; other site
568704006719	Walker B motif; other site
568704006720	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
568704006721	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
568704006722	trimer interface [polypeptide binding]; other site
568704006723	active site
568704006724	Predicted acetyltransferase [General function prediction only]; Region: COG2388
568704006725	Peptidase C1B subfamily (MEROPS database nomenclature); composed of eukaryotic bleomycin hydrolases (BH) and bacterial aminopeptidases C (pepC). The proteins of this subfamily contain a large insert relative to the C1A peptidase (papain) subfamily. BH is...; Region: Peptidase_C1B; cd00585
568704006726	trimer interface [polypeptide binding]; other site
568704006727	active site
568704006728	Peptidase C1B subfamily (MEROPS database nomenclature); composed of eukaryotic bleomycin hydrolases (BH) and bacterial aminopeptidases C (pepC). The proteins of this subfamily contain a large insert relative to the C1A peptidase (papain) subfamily. BH is...; Region: Peptidase_C1B; cd00585
568704006729	trimer interface [polypeptide binding]; other site
568704006730	active site
568704006731	G bulge; other site
568704006732	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
568704006733	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
568704006734	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
568704006735	Walker A/P-loop; other site
568704006736	ATP binding site [chemical binding]; other site
568704006737	Q-loop/lid; other site
568704006738	ABC transporter signature motif; other site
568704006739	Walker B; other site
568704006740	D-loop; other site
568704006741	H-loop/switch region; other site
568704006742	K+ potassium transporter; Region: K_trans; pfam02705
568704006743	pyruvate phosphate dikinase; Provisional; Region: PRK09279
568704006744	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
568704006745	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
568704006746	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
568704006747	HTH domain; Region: HTH_11; pfam08279
568704006748	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
568704006749	FOG: CBS domain [General function prediction only]; Region: COG0517
568704006750	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
568704006751	catalytic core [active]
568704006752	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
568704006753	Bacterial low temperature requirement A protein (LtrA); Region: LtrA; cl01754
568704006754	L-lactate oxidase; Region: L_lactate_ox; TIGR02708
568704006755	L-Lactate oxidase (LOX) FMN-binding domain. LOX is a member of the family of FMN-containing alpha-hydroxyacid oxidases and catalyzes the oxidation of l-lactate using molecular oxygen to generate pyruvate and H2O2.  This family occurs in both prokaryotes...; Region: LOX_like_FMN; cd04737
568704006756	teramer interface [polypeptide binding]; other site
568704006757	active site
568704006758	FMN binding site [chemical binding]; other site
568704006759	catalytic residues [active]
568704006760	CsbD-like; Region: CsbD; pfam05532
568704006761	phosphopentomutase; Provisional; Region: PRK05362
568704006762	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
568704006763	benzoate transport; Region: 2A0115; TIGR00895
568704006764	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704006765	putative substrate translocation pore; other site
568704006766	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
568704006767	benzoate transport; Region: 2A0115; TIGR00895
568704006768	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704006769	putative substrate translocation pore; other site
568704006770	Purine catabolism regulatory protein-like family; Region: PucR; pfam07905
568704006771	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
568704006772	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704006773	H+ Antiporter protein; Region: 2A0121; TIGR00900
568704006774	putative substrate translocation pore; other site
568704006775	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
568704006776	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
568704006777	putative catalytic cysteine [active]
568704006778	gamma-glutamyl kinase; Provisional; Region: PRK05429
568704006779	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
568704006780	nucleotide binding site [chemical binding]; other site
568704006781	homotetrameric interface [polypeptide binding]; other site
568704006782	putative phosphate binding site [ion binding]; other site
568704006783	putative allosteric binding site; other site
568704006784	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
568704006785	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
568704006786	FtsX-like permease family; Region: FtsX; pfam02687
568704006787	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
568704006788	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
568704006789	Walker A/P-loop; other site
568704006790	ATP binding site [chemical binding]; other site
568704006791	Q-loop/lid; other site
568704006792	ABC transporter signature motif; other site
568704006793	Walker B; other site
568704006794	D-loop; other site
568704006795	H-loop/switch region; other site
568704006796	Sortase C (SrtC) or subfamily-3 sortases are membrane cysteine transpeptidases found in Gram-positive bacteria that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. This involves a transpeptidation reaction in which the...; Region: Sortase_C_3; cd05827
568704006797	active site
568704006798	catalytic site [active]
568704006799	fimbrial isopeptide formation D2 domain; Region: RrgB_K2N_iso_D2; TIGR04226
568704006800	Cna protein B-type domain; Region: Cna_B; pfam05738
568704006801	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
568704006802	Cna protein B-type domain; Region: Cna_B; pfam05738
568704006803	Uncharacterized conserved protein (DUF2075); Region: DUF2075; pfam09848
568704006804	Uncharacterized conserved protein [Function unknown]; Region: COG3410
568704006805	Protein of unknown function (DUF2974); Region: DUF2974; pfam11187
568704006806	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
568704006807	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568704006808	non-specific DNA binding site [nucleotide binding]; other site
568704006809	salt bridge; other site
568704006810	sequence-specific DNA binding site [nucleotide binding]; other site
568704006811	Predicted transcriptional regulators [Transcription]; Region: COG1695
568704006812	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
568704006813	hypothetical protein; Validated; Region: PRK07668
568704006814	hypothetical protein; Validated; Region: PRK07668
568704006815	Enterocin A Immunity; Region: EntA_Immun; pfam08951
568704006816	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
568704006817	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
568704006818	active site
568704006819	catalytic tetrad [active]
568704006820	Uncharacterized conserved protein [Function unknown]; Region: COG2966
568704006821	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
568704006822	Protein of unknown function (DUF3815); Region: DUF3815; pfam12821
568704006823	bacteriocin secretion accessory protein; Region: bacteriocin_acc; TIGR01000
568704006824	HlyD family secretion protein; Region: HlyD_3; pfam13437
568704006825	bacteriocin secretion accessory protein; Region: bacteriocin_acc; TIGR01000
568704006826	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39B; cd02418
568704006827	ABC-type bacteriocin transporter; Region: bacteriocin_ABC; TIGR01193
568704006828	putative active site [active]
568704006829	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
568704006830	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704006831	Walker A/P-loop; other site
568704006832	ATP binding site [chemical binding]; other site
568704006833	Q-loop/lid; other site
568704006834	ABC transporter signature motif; other site
568704006835	Walker B; other site
568704006836	D-loop; other site
568704006837	H-loop/switch region; other site
568704006838	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568704006839	ATP binding site [chemical binding]; other site
568704006840	Mg2+ binding site [ion binding]; other site
568704006841	G-X-G motif; other site
568704006842	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
568704006843	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl17736
568704006844	phosphorylation site [posttranslational modification]
568704006845	intermolecular recognition site; other site
568704006846	LytTr DNA-binding domain; Region: LytTR; pfam04397
568704006847	CAAX protease self-immunity; Region: Abi; pfam02517
568704006848	Rrf2 family protein; Region: rrf2_super; TIGR00738
568704006849	Transcriptional regulator; Region: Rrf2; pfam02082
568704006850	Transcriptional regulator; Region: Rrf2; cl17282
568704006851	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704006852	putative substrate translocation pore; other site
568704006853	Enterocin A Immunity; Region: EntA_Immun; pfam08951
568704006854	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
568704006855	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
568704006856	active site
568704006857	catalytic tetrad [active]
568704006858	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
568704006859	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
568704006860	NAD(P) binding site [chemical binding]; other site
568704006861	active site
568704006862	Old yellow enzyme (OYE)-related FMN binding domain, group 4.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as...; Region: OYE_like_4_FMN; cd04735
568704006863	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
568704006864	putative active site [active]
568704006865	putative FMN binding site [chemical binding]; other site
568704006866	putative substrate binding site [chemical binding]; other site
568704006867	putative catalytic residue [active]
568704006868	Short C-terminal domain; Region: SHOCT; pfam09851
568704006869	fumarate hydratase; Reviewed; Region: fumC; PRK00485
568704006870	Class II fumarases; Region: Fumarase_classII; cd01362
568704006871	active site
568704006872	tetramer interface [polypeptide binding]; other site
568704006873	manganese transport protein MntH; Reviewed; Region: PRK00701
568704006874	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
568704006875	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
568704006876	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
568704006877	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
568704006878	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
568704006879	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568704006880	motif II; other site
568704006881	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
568704006882	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704006883	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
568704006884	putative substrate translocation pore; other site
568704006885	multicopper oxidase; Provisional; Region: PRK10965
568704006886	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
568704006887	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
568704006888	Cation efflux family; Region: Cation_efflux; cl00316
568704006889	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
568704006890	dimerization interface [polypeptide binding]; other site
568704006891	putative DNA binding site [nucleotide binding]; other site
568704006892	putative Zn2+ binding site [ion binding]; other site
568704006893	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
568704006894	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
568704006895	metal binding site [ion binding]; metal-binding site
568704006896	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
568704006897	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
568704006898	ABC-ATPase subunit  interface; other site
568704006899	dimer interface [polypeptide binding]; other site
568704006900	putative PBP binding regions; other site
568704006901	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704006902	Walker B; other site
568704006903	D-loop; other site
568704006904	H-loop/switch region; other site
568704006905	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704006906	Walker A/P-loop; other site
568704006907	ATP binding site [chemical binding]; other site
568704006908	Q-loop/lid; other site
568704006909	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
568704006910	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
568704006911	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
568704006912	intersubunit interface [polypeptide binding]; other site
568704006913	atypical (a) SDRs, subgroup 6; Region: SDR_a6; cd05267
568704006914	NADH(P)-binding; Region: NAD_binding_10; pfam13460
568704006915	putative NAD(P) binding site [chemical binding]; other site
568704006916	Metal binding protein TroA_b.  These proteins are predicted to function as initial receptors in ABC transport of metal ions.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding...; Region: TroA_b; cd01020
568704006917	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
568704006918	metal binding site [ion binding]; metal-binding site
568704006919	CrcB-like protein; Region: CRCB; cl09114
568704006920	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
568704006921	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704006922	Alpha-L-rhamnosidase N-terminal domain; Region: Bac_rhamnosid_N; pfam08531
568704006923	Bacterial alpha-L-rhamnosidase; Region: Bac_rhamnosid; pfam05592
568704006924	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
568704006925	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
568704006926	substrate binding pocket [chemical binding]; other site
568704006927	membrane-bound complex binding site; other site
568704006928	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
568704006929	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
568704006930	Subfamily of fatty acid CoA ligase (FACL) similar to Fum10p of Gibberella moniliformis; Region: FACL_fum10p_like; cd05926
568704006931	acyl-activating enzyme (AAE) consensus motif; other site
568704006932	acyl-activating enzyme (AAE) consensus motif; other site
568704006933	putative AMP binding site [chemical binding]; other site
568704006934	putative active site [active]
568704006935	putative CoA binding site [chemical binding]; other site
568704006936	Acyltransferase family; Region: Acyl_transf_3; pfam01757
568704006937	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704006938	aliphatic sulfonates transport ATP-binding subunit; Provisional; Region: ssuB; PRK11247
568704006939	Walker A/P-loop; other site
568704006940	ATP binding site [chemical binding]; other site
568704006941	Q-loop/lid; other site
568704006942	ABC transporter signature motif; other site
568704006943	Walker B; other site
568704006944	D-loop; other site
568704006945	H-loop/switch region; other site
568704006946	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
568704006947	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568704006948	putative PBP binding loops; other site
568704006949	dimer interface [polypeptide binding]; other site
568704006950	ABC-ATPase subunit interface; other site
568704006951	Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only]; Region: COG3382
568704006952	B3/4 domain; Region: B3_4; pfam03483
568704006953	Transposase; Region: DEDD_Tnp_IS110; pfam01548
568704006954	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
568704006955	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
568704006956	PemK-like protein; Region: PemK; pfam02452
568704006957	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
568704006958	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704006959	Walker A/P-loop; other site
568704006960	ATP binding site [chemical binding]; other site
568704006961	Q-loop/lid; other site
568704006962	ABC transporter signature motif; other site
568704006963	Walker B; other site
568704006964	D-loop; other site
568704006965	H-loop/switch region; other site
568704006966	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
568704006967	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704006968	Walker A/P-loop; other site
568704006969	ATP binding site [chemical binding]; other site
568704006970	Q-loop/lid; other site
568704006971	ABC transporter signature motif; other site
568704006972	Walker B; other site
568704006973	D-loop; other site
568704006974	H-loop/switch region; other site
568704006975	H+ Antiporter protein; Region: 2A0121; TIGR00900
568704006976	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704006977	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
568704006978	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
568704006979	23S rRNA interface [nucleotide binding]; other site
568704006980	L3 interface [polypeptide binding]; other site
568704006981	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
568704006982	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
568704006983	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
568704006984	FtsX-like permease family; Region: FtsX; pfam02687
568704006985	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
568704006986	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
568704006987	Walker A/P-loop; other site
568704006988	ATP binding site [chemical binding]; other site
568704006989	Q-loop/lid; other site
568704006990	ABC transporter signature motif; other site
568704006991	Walker B; other site
568704006992	D-loop; other site
568704006993	H-loop/switch region; other site
568704006994	Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA; Region: HTH_TipAL-Mta; cd01106
568704006995	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
568704006996	DNA binding residues [nucleotide binding]
568704006997	dimer interface [polypeptide binding]; other site
568704006998	TipAS antibiotic-recognition domain; Region: TipAS; pfam07739
568704006999	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
568704007000	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
568704007001	dimerization interface 3.5A [polypeptide binding]; other site
568704007002	active site
568704007003	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
568704007004	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13634
568704007005	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
568704007006	Walker A/P-loop; other site
568704007007	ATP binding site [chemical binding]; other site
568704007008	Q-loop/lid; other site
568704007009	ABC transporter signature motif; other site
568704007010	Walker B; other site
568704007011	D-loop; other site
568704007012	H-loop/switch region; other site
568704007013	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13635
568704007014	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
568704007015	Walker A/P-loop; other site
568704007016	ATP binding site [chemical binding]; other site
568704007017	Q-loop/lid; other site
568704007018	ABC transporter signature motif; other site
568704007019	Walker B; other site
568704007020	D-loop; other site
568704007021	H-loop/switch region; other site
568704007022	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
568704007023	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
568704007024	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
568704007025	alphaNTD homodimer interface [polypeptide binding]; other site
568704007026	alphaNTD - beta interaction site [polypeptide binding]; other site
568704007027	alphaNTD - beta' interaction site [polypeptide binding]; other site
568704007028	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
568704007029	30S ribosomal protein S11; Validated; Region: PRK05309
568704007030	Ribosomal protein S13 [Translation, ribosomal structure and biogenesis]; Region: RpsM; COG0099
568704007031	30S ribosomal protein S13; Region: bact_S13; TIGR03631
568704007032	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
568704007033	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
568704007034	rRNA binding site [nucleotide binding]; other site
568704007035	predicted 30S ribosome binding site; other site
568704007036	adenylate kinase; Reviewed; Region: adk; PRK00279
568704007037	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
568704007038	AMP-binding site [chemical binding]; other site
568704007039	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
568704007040	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
568704007041	SecY translocase; Region: SecY; pfam00344
568704007042	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
568704007043	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
568704007044	23S rRNA binding site [nucleotide binding]; other site
568704007045	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
568704007046	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
568704007047	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
568704007048	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
568704007049	5S rRNA interface [nucleotide binding]; other site
568704007050	L27 interface [polypeptide binding]; other site
568704007051	23S rRNA interface [nucleotide binding]; other site
568704007052	L5 interface [polypeptide binding]; other site
568704007053	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
568704007054	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
568704007055	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
568704007056	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
568704007057	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
568704007058	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
568704007059	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
568704007060	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
568704007061	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
568704007062	RNA binding site [nucleotide binding]; other site
568704007063	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
568704007064	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
568704007065	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
568704007066	23S rRNA interface [nucleotide binding]; other site
568704007067	putative translocon interaction site; other site
568704007068	signal recognition particle (SRP54) interaction site; other site
568704007069	L23 interface [polypeptide binding]; other site
568704007070	trigger factor interaction site; other site
568704007071	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
568704007072	23S rRNA interface [nucleotide binding]; other site
568704007073	5S rRNA interface [nucleotide binding]; other site
568704007074	putative antibiotic binding site [chemical binding]; other site
568704007075	L25 interface [polypeptide binding]; other site
568704007076	L27 interface [polypeptide binding]; other site
568704007077	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
568704007078	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
568704007079	G-X-X-G motif; other site
568704007080	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
568704007081	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
568704007082	putative translocon binding site; other site
568704007083	protein-rRNA interface [nucleotide binding]; other site
568704007084	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
568704007085	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
568704007086	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
568704007087	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
568704007088	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
568704007089	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
568704007090	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
568704007091	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
568704007092	phosphate-starvation-inducible protein PsiE; Provisional; Region: PRK02833
568704007093	peroxiredoxin; Region: AhpC; TIGR03137
568704007094	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
568704007095	dimer interface [polypeptide binding]; other site
568704007096	decamer (pentamer of dimers) interface [polypeptide binding]; other site
568704007097	catalytic triad [active]
568704007098	peroxidatic and resolving cysteines [active]
568704007099	Predicted transcriptional regulator [Transcription]; Region: COG2378
568704007100	WYL domain; Region: WYL; pfam13280
568704007101	elongation factor G; Reviewed; Region: PRK12739
568704007102	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
568704007103	G1 box; other site
568704007104	putative GEF interaction site [polypeptide binding]; other site
568704007105	GTP/Mg2+ binding site [chemical binding]; other site
568704007106	Switch I region; other site
568704007107	G2 box; other site
568704007108	G3 box; other site
568704007109	Switch II region; other site
568704007110	G4 box; other site
568704007111	G5 box; other site
568704007112	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
568704007113	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
568704007114	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
568704007115	30S ribosomal protein S7; Validated; Region: PRK05302
568704007116	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
568704007117	S17 interaction site [polypeptide binding]; other site
568704007118	S8 interaction site; other site
568704007119	16S rRNA interaction site [nucleotide binding]; other site
568704007120	streptomycin interaction site [chemical binding]; other site
568704007121	23S rRNA interaction site [nucleotide binding]; other site
568704007122	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
568704007123	Predicted outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG4932
568704007124	Cna protein B-type domain; Region: Cna_B; pfam05738
568704007125	Cna protein B-type domain; Region: Cna_B; pfam05738
568704007126	Cna protein B-type domain; Region: Cna_B; pfam05738
568704007127	Cna protein B-type domain; Region: Cna_B; pfam05738
568704007128	Cna protein B-type domain; Region: Cna_B; pfam05738
568704007129	Cna protein B-type domain; Region: Cna_B; pfam05738
568704007130	Cna protein B-type domain; Region: Cna_B; pfam05738
568704007131	Cna protein B-type domain; Region: Cna_B; pfam05738
568704007132	Cna protein B-type domain; Region: Cna_B; pfam05738
568704007133	Cna protein B-type domain; Region: Cna_B; pfam05738
568704007134	Cna protein B-type domain; Region: Cna_B; pfam05738
568704007135	Cna protein B-type domain; Region: Cna_B; pfam05738
568704007136	Cna protein B-type domain; Region: Cna_B; pfam05738
568704007137	Cna protein B-type domain; Region: Cna_B; pfam05738
568704007138	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
568704007139	DNA-directed RNA polymerase subunit beta'; Provisional; Region: PRK00566
568704007140	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
568704007141	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
568704007142	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
568704007143	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
568704007144	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
568704007145	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
568704007146	DNA binding site [nucleotide binding]
568704007147	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
568704007148	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
568704007149	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
568704007150	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
568704007151	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
568704007152	RPB1 interaction site [polypeptide binding]; other site
568704007153	RPB10 interaction site [polypeptide binding]; other site
568704007154	RPB11 interaction site [polypeptide binding]; other site
568704007155	RPB3 interaction site [polypeptide binding]; other site
568704007156	RPB12 interaction site [polypeptide binding]; other site
568704007157	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
568704007158	Clp amino terminal domain; Region: Clp_N; pfam02861
568704007159	Clp amino terminal domain; Region: Clp_N; pfam02861
568704007160	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568704007161	Walker A motif; other site
568704007162	ATP binding site [chemical binding]; other site
568704007163	Walker B motif; other site
568704007164	arginine finger; other site
568704007165	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568704007166	Walker A motif; other site
568704007167	ATP binding site [chemical binding]; other site
568704007168	Walker B motif; other site
568704007169	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
568704007170	Firmicute transcriptional repressor of class III stress genes (CtsR); Region: CtsR; pfam05848
568704007171	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
568704007172	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
568704007173	dimer interface [polypeptide binding]; other site
568704007174	putative anticodon binding site; other site
568704007175	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
568704007176	motif 1; other site
568704007177	active site
568704007178	motif 2; other site
568704007179	motif 3; other site
568704007180	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
568704007181	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
568704007182	FMN binding site [chemical binding]; other site
568704007183	active site
568704007184	catalytic residues [active]
568704007185	substrate binding site [chemical binding]; other site
568704007186	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
568704007187	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
568704007188	dimerization interface [polypeptide binding]; other site
568704007189	domain crossover interface; other site
568704007190	redox-dependent activation switch; other site
568704007191	Protein of unknown function (DUF3139); Region: DUF3139; pfam11337
568704007192	FtsH Extracellular; Region: FtsH_ext; pfam06480
568704007193	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
568704007194	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568704007195	Walker A motif; other site
568704007196	ATP binding site [chemical binding]; other site
568704007197	Walker B motif; other site
568704007198	arginine finger; other site
568704007199	Peptidase family M41; Region: Peptidase_M41; pfam01434
568704007200	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
568704007201	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
568704007202	active site
568704007203	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
568704007204	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
568704007205	Ligand Binding Site [chemical binding]; other site
568704007206	TilS substrate C-terminal domain; Region: TilS_C; smart00977
568704007207	hypothetical protein; Provisional; Region: PRK08582
568704007208	S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692
568704007209	RNA binding site [nucleotide binding]; other site
568704007210	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
568704007211	Septum formation initiator; Region: DivIC; pfam04977
568704007212	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
568704007213	RNA binding surface [nucleotide binding]; other site
568704007214	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
568704007215	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
568704007216	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
568704007217	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
568704007218	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
568704007219	ATP binding site [chemical binding]; other site
568704007220	putative Mg++ binding site [ion binding]; other site
568704007221	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
568704007222	nucleotide binding region [chemical binding]; other site
568704007223	ATP-binding site [chemical binding]; other site
568704007224	TRCF domain; Region: TRCF; pfam03461
568704007225	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
568704007226	putative active site [active]
568704007227	catalytic residue [active]
568704007228	L-lactate dehydrogenase; Reviewed; Region: ldh; PRK00066
568704007229	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
568704007230	tetramer (dimer of dimers) interface [polypeptide binding]; other site
568704007231	NAD binding site [chemical binding]; other site
568704007232	dimer interface [polypeptide binding]; other site
568704007233	substrate binding site [chemical binding]; other site
568704007234	Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229
568704007235	Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229
568704007236	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
568704007237	Predicted transcriptional regulators [Transcription]; Region: COG1695
568704007238	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
568704007239	Predicted membrane protein [Function unknown]; Region: COG1511
568704007240	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
568704007241	YhgE/Pip C-terminal domain; Region: pip_yhgE_Cterm; TIGR03062
568704007242	Flavodoxin-like fold; Region: Flavodoxin_2; pfam02525
568704007243	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
568704007244	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
568704007245	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
568704007246	Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376
568704007247	glutamate synthase subunit beta; Reviewed; Region: gltD; PRK12810
568704007248	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
568704007249	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
568704007250	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
568704007251	active site
568704007252	dimer interface [polypeptide binding]; other site
568704007253	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
568704007254	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
568704007255	active site
568704007256	FMN binding site [chemical binding]; other site
568704007257	substrate binding site [chemical binding]; other site
568704007258	3Fe-4S cluster binding site [ion binding]; other site
568704007259	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
568704007260	domain interface; other site
568704007261	QueT transporter; Region: QueT; pfam06177
568704007262	PemK-like protein; Region: PemK; pfam02452
568704007263	hypothetical protein; Region: PHA01623
568704007264	alanine racemase; Reviewed; Region: alr; PRK00053
568704007265	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
568704007266	active site
568704007267	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
568704007268	dimer interface [polypeptide binding]; other site
568704007269	substrate binding site [chemical binding]; other site
568704007270	catalytic residues [active]
568704007271	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
568704007272	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
568704007273	DEAD-like helicases superfamily; Region: DEXDc; smart00487
568704007274	ATP binding site [chemical binding]; other site
568704007275	Mg++ binding site [ion binding]; other site
568704007276	motif III; other site
568704007277	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
568704007278	nucleotide binding region [chemical binding]; other site
568704007279	ATP-binding site [chemical binding]; other site
568704007280	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
568704007281	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
568704007282	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
568704007283	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
568704007284	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
568704007285	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
568704007286	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
568704007287	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
568704007288	hinge; other site
568704007289	active site
568704007290	CTP synthetase; Validated; Region: pyrG; PRK05380
568704007291	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
568704007292	Catalytic site [active]
568704007293	active site
568704007294	UTP binding site [chemical binding]; other site
568704007295	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
568704007296	active site
568704007297	putative oxyanion hole; other site
568704007298	catalytic triad [active]
568704007299	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
568704007300	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
568704007301	Protein of unknown function (DUF1211); Region: DUF1211; cl01421
568704007302	DNA-directed RNA polymerase delta subunit; Region: RNA_pol_delta; pfam05066
568704007303	Domain of unknown function (DUF1934); Region: DUF1934; cl01870
568704007304	Domain of unknown function (DUF1934); Region: DUF1934; cl01870
568704007305	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
568704007306	HD superfamily phosphohydrolases [General function prediction only]; Region: COG1078
568704007307	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
568704007308	Zn2+ binding site [ion binding]; other site
568704007309	Mg2+ binding site [ion binding]; other site
568704007310	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
568704007311	nudix motif; other site
568704007312	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
568704007313	Uncharacterized conserved protein [Function unknown]; Region: COG1434
568704007314	putative active site [active]
568704007315	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
568704007316	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
568704007317	ASC-1 homology domain, subfamily similar to Pyrococcus furiosus Pf0470. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_PF0470_like; cd06555
568704007318	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
568704007319	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
568704007320	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
568704007321	active site
568704007322	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
568704007323	putative trimer interface [polypeptide binding]; other site
568704007324	putative CoA binding site [chemical binding]; other site
568704007325	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
568704007326	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
568704007327	Substrate binding site; other site
568704007328	Mg++ binding site; other site
568704007329	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
568704007330	VanZ like family; Region: VanZ; pfam04892
568704007331	RDD family; Region: RDD; pfam06271
568704007332	pur operon repressor; Provisional; Region: PRK09213
568704007333	Bacterial purine repressor, N-terminal; Region: PuR_N; pfam09182
568704007334	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
568704007335	active site
568704007336	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4619
568704007337	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704007338	Walker A/P-loop; other site
568704007339	ATP binding site [chemical binding]; other site
568704007340	Q-loop/lid; other site
568704007341	ABC transporter signature motif; other site
568704007342	Walker B; other site
568704007343	D-loop; other site
568704007344	H-loop/switch region; other site
568704007345	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG0390
568704007346	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
568704007347	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
568704007348	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00128
568704007349	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
568704007350	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
568704007351	Protein of unknown function (DUF1021); Region: DUF1021; pfam06257
568704007352	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
568704007353	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568704007354	S-adenosylmethionine binding site [chemical binding]; other site
568704007355	ribonuclease M5; Region: 5S_RNA_mat_M5; TIGR00334
568704007356	TOPRIM_ RNase M5_like: The topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain found in Ribonuclease M5: (RNase M5) and other small primase-like proteins from bacteria and archaea.  RNase M5 catalyzes the maturation of 5S rRNA in low...; Region: TOPRIM_RNase_M5_like; cd01027
568704007357	putative active site [active]
568704007358	putative metal binding site [ion binding]; other site
568704007359	Domain of unknown function (DUF4093); Region: DUF4093; pfam13331
568704007360	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
568704007361	active site
568704007362	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cl00163
568704007363	active site
568704007364	phosphorylation site [posttranslational modification]
568704007365	Class I aldolases; Region: Aldolase_Class_I; cl17187
568704007366	Aldose 1-epimerase, similar to Lactococcus lactis lacX; Region: Aldose_epim_lacX; cd09024
568704007367	active site
568704007368	catalytic residues [active]
568704007369	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
568704007370	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568704007371	active site
568704007372	phosphorylation site [posttranslational modification]
568704007373	intermolecular recognition site; other site
568704007374	dimerization interface [polypeptide binding]; other site
568704007375	LytTr DNA-binding domain; Region: LytTR; pfam04397
568704007376	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
568704007377	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
568704007378	ATP binding site [chemical binding]; other site
568704007379	Mg2+ binding site [ion binding]; other site
568704007380	G-X-G motif; other site
568704007381	Transmembrane protein 231; Region: TM231; pfam10149
568704007382	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704007383	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
568704007384	Walker A/P-loop; other site
568704007385	ATP binding site [chemical binding]; other site
568704007386	Q-loop/lid; other site
568704007387	ABC transporter signature motif; other site
568704007388	Walker B; other site
568704007389	D-loop; other site
568704007390	H-loop/switch region; other site
568704007391	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
568704007392	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704007393	Walker A/P-loop; other site
568704007394	ATP binding site [chemical binding]; other site
568704007395	Q-loop/lid; other site
568704007396	ABC transporter signature motif; other site
568704007397	Walker B; other site
568704007398	D-loop; other site
568704007399	H-loop/switch region; other site
568704007400	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
568704007401	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568704007402	non-specific DNA binding site [nucleotide binding]; other site
568704007403	salt bridge; other site
568704007404	sequence-specific DNA binding site [nucleotide binding]; other site
568704007405	methionyl-tRNA synthetase; Reviewed; Region: PRK12267
568704007406	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
568704007407	active site
568704007408	HIGH motif; other site
568704007409	KMSKS motif; other site
568704007410	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
568704007411	tRNA binding surface [nucleotide binding]; other site
568704007412	anticodon binding site; other site
568704007413	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
568704007414	dimer interface [polypeptide binding]; other site
568704007415	putative tRNA-binding site [nucleotide binding]; other site
568704007416	proline-specific peptidase, Bacillus coagulans-type subfamily; Region: pro_imino_pep_2; TIGR01250
568704007417	Protein of unknown function DUF72; Region: DUF72; pfam01904
568704007418	MutT homolog-1 (MTH1) is a member of the Nudix hydrolase superfamily. MTH1, the mammalian counterpart of MutT, hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP and 2-hydroxy-ATP, to monophosphates, thereby preventing the...; Region: MTH1; cd03427
568704007419	putative active site [active]
568704007420	nucleotide binding site [chemical binding]; other site
568704007421	nudix motif; other site
568704007422	putative metal binding site [ion binding]; other site
568704007423	NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195
568704007424	L-lactate dehydrogenase; Region: L-LDH-NAD; TIGR01771
568704007425	LDH/MDH dimer interface [polypeptide binding]; other site
568704007426	NAD(P) binding site [chemical binding]; other site
568704007427	substrate binding site [chemical binding]; other site
568704007428	Protein of unknown function (DUF1211); Region: DUF1211; cl01421
568704007429	NAD-dependent deacetylase; Provisional; Region: PRK00481
568704007430	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
568704007431	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
568704007432	substrate binding site [chemical binding]; other site
568704007433	Predicted secreted protein [Function unknown]; Region: COG4086
568704007434	Protein of unknown function (DUF1002); Region: DUF1002; pfam06207
568704007435	exopolyphosphatase; Region: exo_poly_only; TIGR03706
568704007436	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
568704007437	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
568704007438	Polyphosphate kinase C-terminal domain; Region: PP_kinase_C; pfam13090
568704007439	Catalytic C-terminal domain, first repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C1_like; cd09165
568704007440	putative domain interface [polypeptide binding]; other site
568704007441	putative active site [active]
568704007442	catalytic site [active]
568704007443	Catalytic C-terminal domain, second repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C2_like; cd09168
568704007444	putative domain interface [polypeptide binding]; other site
568704007445	putative active site [active]
568704007446	catalytic site [active]
568704007447	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
568704007448	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
568704007449	exopolyphosphatase; Region: exo_poly_only; TIGR03706
568704007450	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
568704007451	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
568704007452	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
568704007453	active site
568704007454	catalytic tetrad [active]
568704007455	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
568704007456	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568704007457	S-adenosylmethionine binding site [chemical binding]; other site
568704007458	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
568704007459	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
568704007460	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
568704007461	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; Region: MATE_yoeA_like; cd13138
568704007462	Repair protein; Region: Repair_PSII; pfam04536
568704007463	Uncharacterized conserved protein [Function unknown]; Region: LemA; COG1704
568704007464	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
568704007465	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
568704007466	active site
568704007467	HIGH motif; other site
568704007468	dimer interface [polypeptide binding]; other site
568704007469	KMSKS motif; other site
568704007470	H+ Antiporter protein; Region: 2A0121; TIGR00900
568704007471	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes [Energy production and conversion]; Region: Lpd; COG1249
568704007472	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
568704007473	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
568704007474	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
568704007475	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704007476	Walker A/P-loop; other site
568704007477	ATP binding site [chemical binding]; other site
568704007478	Q-loop/lid; other site
568704007479	ABC transporter signature motif; other site
568704007480	Walker B; other site
568704007481	D-loop; other site
568704007482	H-loop/switch region; other site
568704007483	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568704007484	dimer interface [polypeptide binding]; other site
568704007485	conserved gate region; other site
568704007486	ABC-ATPase subunit interface; other site
568704007487	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
568704007488	Superfamily I DNA and RNA helicases [General function prediction only]; Region: COG3973
568704007489	Part of AAA domain; Region: AAA_19; pfam13245
568704007490	Family description; Region: UvrD_C_2; pfam13538
568704007491	Transcriptional regulator [Transcription]; Region: LysR; COG0583
568704007492	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568704007493	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
568704007494	dimerization interface [polypeptide binding]; other site
568704007495	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
568704007496	C4-dicarboxylate transporters of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family; Region: TDT_C4-dicarb_trans; cd09325
568704007497	gating phenylalanine in ion channel; other site
568704007498	ABC-2 type transporter; Region: ABC2_membrane; cl17235
568704007499	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
568704007500	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704007501	Walker A/P-loop; other site
568704007502	ATP binding site [chemical binding]; other site
568704007503	Q-loop/lid; other site
568704007504	ABC transporter signature motif; other site
568704007505	Walker B; other site
568704007506	D-loop; other site
568704007507	H-loop/switch region; other site
568704007508	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
568704007509	putative DNA binding site [nucleotide binding]; other site
568704007510	dimerization interface [polypeptide binding]; other site
568704007511	putative Zn2+ binding site [ion binding]; other site
568704007512	CAAX protease self-immunity; Region: Abi; pfam02517
568704007513	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
568704007514	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
568704007515	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
568704007516	Walker A/P-loop; other site
568704007517	ATP binding site [chemical binding]; other site
568704007518	Q-loop/lid; other site
568704007519	ABC transporter signature motif; other site
568704007520	Walker B; other site
568704007521	D-loop; other site
568704007522	H-loop/switch region; other site
568704007523	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
568704007524	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215
568704007525	Transcriptional regulators [Transcription]; Region: MarR; COG1846
568704007526	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
568704007527	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704007528	Walker A/P-loop; other site
568704007529	ATP binding site [chemical binding]; other site
568704007530	Q-loop/lid; other site
568704007531	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
568704007532	Excinuclease ATPase subunit [DNA replication, recombination, and repair]; Region: UvrA; COG0178
568704007533	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704007534	ABC transporter signature motif; other site
568704007535	Walker B; other site
568704007536	D-loop; other site
568704007537	H-loop/switch region; other site
568704007538	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704007539	Walker A/P-loop; other site
568704007540	ATP binding site [chemical binding]; other site
568704007541	Q-loop/lid; other site
568704007542	ABC transporter signature motif; other site
568704007543	Walker B; other site
568704007544	D-loop; other site
568704007545	H-loop/switch region; other site
568704007546	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
568704007547	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
568704007548	active site
568704007549	catalytic tetrad [active]
568704007550	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
568704007551	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568704007552	Protein of unknown function (DUF1275); Region: DUF1275; pfam06912
568704007553	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
568704007554	catalytic core [active]
568704007555	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cl11399
568704007556	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568704007557	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
568704007558	active site
568704007559	motif I; other site
568704007560	motif II; other site
568704007561	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568704007562	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
568704007563	RNA/DNA hybrid binding site [nucleotide binding]; other site
568704007564	active site
568704007565	Transcriptional regulator [Transcription]; Region: LysR; COG0583
568704007566	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568704007567	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
568704007568	dimerization interface [polypeptide binding]; other site
568704007569	Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436
568704007570	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
568704007571	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568704007572	homodimer interface [polypeptide binding]; other site
568704007573	catalytic residue [active]
568704007574	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
568704007575	recombinase A; Provisional; Region: recA; PRK09354
568704007576	hexamer interface [polypeptide binding]; other site
568704007577	Walker A motif; other site
568704007578	ATP binding site [chemical binding]; other site
568704007579	Walker B motif; other site
568704007580	Protein of unknown function (DUF554); Region: DUF554; pfam04474
568704007581	putative PTS system  transporter subunits IIBC; Provisional; Region: PRK11404
568704007582	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
568704007583	active site
568704007584	P-loop; other site
568704007585	phosphorylation site [posttranslational modification]
568704007586	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
568704007587	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
568704007588	active site
568704007589	phosphorylation site [posttranslational modification]
568704007590	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
568704007591	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
568704007592	putative substrate binding site [chemical binding]; other site
568704007593	putative ATP binding site [chemical binding]; other site
568704007594	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
568704007595	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
568704007596	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
568704007597	putative active site [active]
568704007598	glycerol kinase; Provisional; Region: glpK; PRK00047
568704007599	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
568704007600	N- and C-terminal domain interface [polypeptide binding]; other site
568704007601	active site
568704007602	MgATP binding site [chemical binding]; other site
568704007603	catalytic site [active]
568704007604	metal binding site [ion binding]; metal-binding site
568704007605	glycerol binding site [chemical binding]; other site
568704007606	homotetramer interface [polypeptide binding]; other site
568704007607	homodimer interface [polypeptide binding]; other site
568704007608	FBP binding site [chemical binding]; other site
568704007609	protein IIAGlc interface [polypeptide binding]; other site
568704007610	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; pfam01977
568704007611	3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme metabolism]; Region: UbiX; COG0163
568704007612	Flavoprotein; Region: Flavoprotein; pfam02441
568704007613	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
568704007614	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
568704007615	Transcriptional regulator [Transcription]; Region: LysR; COG0583
568704007616	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568704007617	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
568704007618	dimerization interface [polypeptide binding]; other site
568704007619	Transcriptional regulators [Transcription]; Region: MarR; COG1846
568704007620	MarR family; Region: MarR_2; pfam12802
568704007621	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704007622	Major Facilitator Superfamily; Region: MFS_1; pfam07690
568704007623	putative substrate translocation pore; other site
568704007624	hypothetical protein; Provisional; Region: PRK06357
568704007625	intersubunit interface [polypeptide binding]; other site
568704007626	active site
568704007627	Zn2+ binding site [ion binding]; other site
568704007628	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
568704007629	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
568704007630	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
568704007631	active site
568704007632	P-loop; other site
568704007633	phosphorylation site [posttranslational modification]
568704007634	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
568704007635	active site
568704007636	phosphorylation site [posttranslational modification]
568704007637	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
568704007638	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
568704007639	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
568704007640	rhamnulose-1-phosphate aldolase; Provisional; Region: PRK03634
568704007641	intersubunit interface [polypeptide binding]; other site
568704007642	active site
568704007643	Zn2+ binding site [ion binding]; other site
568704007644	L-rhamnose isomerase; Provisional; Region: PRK01076
568704007645	Domain of unknown function (DUF718); Region: DUF718; cl01281
568704007646	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
568704007647	N- and C-terminal domain interface [polypeptide binding]; other site
568704007648	rhamnulokinase; Region: rhamnulo_kin; TIGR02627
568704007649	active site
568704007650	putative catalytic site [active]
568704007651	metal binding site [ion binding]; metal-binding site
568704007652	ATP binding site [chemical binding]; other site
568704007653	carbohydrate binding site [chemical binding]; other site
568704007654	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704007655	putative substrate translocation pore; other site
568704007656	Cupin domain; Region: Cupin_2; pfam07883
568704007657	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
568704007658	Zn-dependent alcohol dehydrogenases, class III [Energy production and conversion]; Region: AdhC; COG1062
568704007659	Benzyl alcohol dehydrogenase; Region: benzyl_alcohol_DH; cd08278
568704007660	catalytic Zn binding site [ion binding]; other site
568704007661	NAD binding site [chemical binding]; other site
568704007662	structural Zn binding site [ion binding]; other site
568704007663	Protein of unknown function (DUF1093); Region: DUF1093; pfam06486
568704007664	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
568704007665	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
568704007666	Ca binding site [ion binding]; other site
568704007667	active site
568704007668	catalytic site [active]
568704007669	Right handed beta helix region; Region: Beta_helix; pfam13229
568704007670	Heparinase II/III-like protein; Region: Hepar_II_III; pfam07940
568704007671	Preprotein translocase subunit; Region: YajC; pfam02699
568704007672	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
568704007673	active pocket/dimerization site; other site
568704007674	active site
568704007675	phosphorylation site [posttranslational modification]
568704007676	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
568704007677	PTS system sorbose-specific iic component; Region: EII-Sor; pfam03609
568704007678	PTS system sorbose subfamily IIB component; Region: PTSIIB_sorb; pfam03830
568704007679	active site
568704007680	phosphorylation site [posttranslational modification]
568704007681	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
568704007682	Transcriptional regulator [Transcription]; Region: IclR; COG1414
568704007683	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
568704007684	Bacterial transcriptional regulator; Region: IclR; pfam01614
568704007685	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
568704007686	2-deoxy-D-gluconate 3-dehydrogenase; Provisional; Region: PRK06935
568704007687	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
568704007688	NADP binding site [chemical binding]; other site
568704007689	homodimer interface [polypeptide binding]; other site
568704007690	active site
568704007691	2-keto-3-deoxy-6-phosphogluconate aldolase [Carbohydrate transport and metabolism]; Region: Eda; COG0800
568704007692	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
568704007693	active site
568704007694	intersubunit interface [polypeptide binding]; other site
568704007695	catalytic residue [active]
568704007696	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
568704007697	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
568704007698	substrate binding site [chemical binding]; other site
568704007699	ATP binding site [chemical binding]; other site
568704007700	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
568704007701	tetramer (dimer of dimers) interface [polypeptide binding]; other site
568704007702	active site
568704007703	dimer interface [polypeptide binding]; other site
568704007704	Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues; Region: GAG_Lyase; cd01083
568704007705	substrate binding site [chemical binding]; other site
568704007706	catalytic residues [active]
568704007707	Melibiase; Region: Melibiase; pfam02065
568704007708	PTS system sorbose subfamily IIB component; Region: PTSIIB_sorb; pfam03830
568704007709	phosphorylation site [posttranslational modification]
568704007710	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
568704007711	PTS system sorbose-specific iic component; Region: EII-Sor; pfam03609
568704007712	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
568704007713	active pocket/dimerization site; other site
568704007714	active site
568704007715	phosphorylation site [posttranslational modification]
568704007716	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568704007717	DNA-binding site [nucleotide binding]; DNA binding site
568704007718	Transcriptional regulators [Transcription]; Region: PurR; COG1609
568704007719	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
568704007720	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
568704007721	Glycoside Hydrolases Family 4; GlvA- and pagL-like glycosidases; Region: GH4_GlvA_pagL_like; cd05298
568704007722	NAD binding site [chemical binding]; other site
568704007723	sugar binding site [chemical binding]; other site
568704007724	divalent metal binding site [ion binding]; other site
568704007725	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
568704007726	dimer interface [polypeptide binding]; other site
568704007727	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
568704007728	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
568704007729	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
568704007730	active site turn [active]
568704007731	phosphorylation site [posttranslational modification]
568704007732	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
568704007733	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
568704007734	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
568704007735	Walker A/P-loop; other site
568704007736	ATP binding site [chemical binding]; other site
568704007737	Q-loop/lid; other site
568704007738	ABC transporter signature motif; other site
568704007739	Walker B; other site
568704007740	D-loop; other site
568704007741	H-loop/switch region; other site
568704007742	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
568704007743	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568704007744	non-specific DNA binding site [nucleotide binding]; other site
568704007745	salt bridge; other site
568704007746	sequence-specific DNA binding site [nucleotide binding]; other site
568704007747	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
568704007748	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
568704007749	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
568704007750	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
568704007751	putative active site [active]
568704007752	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
568704007753	HPr interaction site; other site
568704007754	glycerol kinase (GK) interaction site [polypeptide binding]; other site
568704007755	active site
568704007756	phosphorylation site [posttranslational modification]
568704007757	Protein of unknown function (DUF1341); Region: DUF1341; pfam07071
568704007758	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
568704007759	dihydroorotase; Provisional; Region: PRK09237
568704007760	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
568704007761	active site
568704007762	Domain of unknown function (DUF4310); Region: DUF4310; pfam14187
568704007763	Domain of unknown function (DUF4311); Region: DUF4311; cl11919
568704007764	Domain of unknown function (DUF4312); Region: DUF4312; cl11917
568704007765	Glycine-rich SFCGS; Region: Gly_rich_SFCGS; pfam14272
568704007766	PRD domain protein EF_0829/AHA_3910; Region: EF_0829; TIGR03582
568704007767	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
568704007768	HTH domain; Region: HTH_11; pfam08279
568704007769	HTH domain; Region: HTH_11; pfam08279
568704007770	PRD domain; Region: PRD; pfam00874
568704007771	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
568704007772	active site
568704007773	P-loop; other site
568704007774	phosphorylation site [posttranslational modification]
568704007775	Class I aldolases; Region: Aldolase_Class_I; cl17187
568704007776	catalytic residue [active]
568704007777	PTS system glucitol/sorbitol-specific IIA component; Region: PTSIIA_gutA; pfam03829
568704007778	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
568704007779	PTS system, glucitol/sorbitol-specific, IIBC component; Region: EIIBC-GUT; TIGR00825
568704007780	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
568704007781	PTS system enzyme II sorbitol-specific factor; Region: EII-GUT; pfam03608
568704007782	Glucitol operon activator protein (GutM); Region: GutM; pfam06923
568704007783	M protein trans-acting positive regulator (MGA) HTH domain; Region: HTH_Mga; pfam08280
568704007784	HTH domain; Region: HTH_11; pfam08279
568704007785	PRD domain; Region: PRD; pfam00874
568704007786	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cl00163
568704007787	active site
568704007788	phosphorylation site [posttranslational modification]
568704007789	sorbitol-6-phosphate 2-dehydrogenase; Provisional; Region: PRK06171
568704007790	classical (c) SDRs; Region: SDR_c; cd05233
568704007791	NAD(P) binding site [chemical binding]; other site
568704007792	active site
568704007793	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
568704007794	Plasmid encoded toxin Txe; Region: Plasmid_Txe; cl17389
568704007795	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
568704007796	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
568704007797	intersubunit interface [polypeptide binding]; other site
568704007798	active site
568704007799	Zn2+ binding site [ion binding]; other site
568704007800	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568704007801	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
568704007802	active site
568704007803	motif I; other site
568704007804	motif II; other site
568704007805	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568704007806	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
568704007807	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
568704007808	AP (apurinic/apyrimidinic) site pocket; other site
568704007809	DNA interaction; other site
568704007810	Metal-binding active site; metal-binding site
568704007811	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
568704007812	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
568704007813	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
568704007814	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
568704007815	active site
568704007816	dimer interface [polypeptide binding]; other site
568704007817	magnesium binding site [ion binding]; other site
568704007818	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
568704007819	active site
568704007820	P-loop; other site
568704007821	phosphorylation site [posttranslational modification]
568704007822	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: PRK12997
568704007823	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
568704007824	active site
568704007825	phosphorylation site [posttranslational modification]
568704007826	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
568704007827	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
568704007828	KxYKxGKxW signal peptide; Region: KxYKxGKxW; TIGR03715
568704007829	Peptidase S8 family domain in Streptococcal C5a peptidases; Region: Peptidases_S8_C5a_Peptidase; cd07475
568704007830	catalytic triad [active]
568704007831	putative active site [active]
568704007832	Fn3-like domain (DUF1034); Region: DUF1034; pfam06280
568704007833	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
568704007834	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
568704007835	nucleotide binding site [chemical binding]; other site
568704007836	Peptidase family M54, also called archaemetzincins or archaelysins; Region: Peptidase_M54; cl17349
568704007837	Glycosylasparaginase catalyzes the hydrolysis of the glycosylamide bond of asparagine-linked glycoproteins. This enzyme is an amidase located inside lysosomes. Mutation of this gene in humans causes a genetic disorder known as aspartylglycosaminuria (AGU)...; Region: Glycosylasparaginase; cd04513
568704007838	active site
568704007839	dimer interface [polypeptide binding]; other site
568704007840	catalytic nucleophile [active]
568704007841	M20 Peptidase Xaa-His dipeptidase (PepV) degrades hydrophobic dipeptides; Region: M20_PepV; cd03888
568704007842	dipeptidase, putative; Region: dipeptidaselike; TIGR01887
568704007843	active site
568704007844	metal binding site [ion binding]; metal-binding site
568704007845	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
568704007846	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568704007847	DNA-binding site [nucleotide binding]; DNA binding site
568704007848	UTRA domain; Region: UTRA; pfam07702
568704007849	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704007850	Major Facilitator Superfamily; Region: MFS_1; pfam07690
568704007851	putative substrate translocation pore; other site
568704007852	Alpha-L-fucosidase; Region: Alpha_L_fucos; cl12119
568704007853	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
568704007854	Histone acetyltransferase HPA2 and related acetyltransferases [Transcription / General function prediction only]; Region: WecD; COG0454
568704007855	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568704007856	Coenzyme A binding pocket [chemical binding]; other site
568704007857	Hydrolase of X-linked nucleoside diphosphate N terminal; Region: Nudix_N; pfam12535
568704007858	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_14; cd04672
568704007859	nudix motif; other site
568704007860	Protein of unknown function (DUF3923); Region: DUF3923; pfam13061
568704007861	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
568704007862	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568704007863	non-specific DNA binding site [nucleotide binding]; other site
568704007864	salt bridge; other site
568704007865	sequence-specific DNA binding site [nucleotide binding]; other site
568704007866	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
568704007867	The enzymes of glycosyl hydrolase family 31 (GH31) occur in prokaryotes, eukaryotes, and archaea with a wide range of hydrolytic activities, including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-xylosidase, 6-alpha-glucosyltransferase; Region: GH31; cl11402
568704007868	active site
568704007869	catalytic site [active]
568704007870	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
568704007871	sugar binding site [chemical binding]; other site
568704007872	Cohesin domain, interaction partner of dockerin; Region: Type_III_cohesin_like; cd08759
568704007873	putative dockerin binding interface; other site
568704007874	ADP-ribose pyrophosphatase [Nucleotide transport and metabolism]; Region: COG1051
568704007875	nudix motif; other site
568704007876	Uncharacterized conserved protein [General function prediction only]; Region: COG4111
568704007877	Isochorismatase family; Region: Isochorismatase; pfam00857
568704007878	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
568704007879	catalytic triad [active]
568704007880	conserved cis-peptide bond; other site
568704007881	nicotinate phosphoribosyltransferase; Validated; Region: PRK09243
568704007882	Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction...; Region: NAPRTase_A; cd01570
568704007883	active site
568704007884	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
568704007885	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
568704007886	active site
568704007887	catalytic site [active]
568704007888	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
568704007889	Low molecular weight phosphatase family; Region: LMWPc; cd00115
568704007890	active site
568704007891	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
568704007892	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
568704007893	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
568704007894	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568704007895	dimer interface [polypeptide binding]; other site
568704007896	conserved gate region; other site
568704007897	putative PBP binding loops; other site
568704007898	ABC-ATPase subunit interface; other site
568704007899	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
568704007900	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568704007901	dimer interface [polypeptide binding]; other site
568704007902	conserved gate region; other site
568704007903	putative PBP binding loops; other site
568704007904	ABC-ATPase subunit interface; other site
568704007905	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
568704007906	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704007907	Walker A/P-loop; other site
568704007908	ATP binding site [chemical binding]; other site
568704007909	Q-loop/lid; other site
568704007910	ABC transporter signature motif; other site
568704007911	Walker B; other site
568704007912	D-loop; other site
568704007913	H-loop/switch region; other site
568704007914	TOBE domain; Region: TOBE_2; pfam08402
568704007915	Major Facilitator Superfamily; Region: MFS_1; pfam07690
568704007916	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
568704007917	Beta-lactamase; Region: Beta-lactamase; pfam00144
568704007918	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
568704007919	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
568704007920	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
568704007921	putative active site [active]
568704007922	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
568704007923	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
568704007924	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
568704007925	putative active site [active]
568704007926	PTS system sorbose subfamily IIB component; Region: PTSIIB_sorb; pfam03830
568704007927	active site
568704007928	phosphorylation site [posttranslational modification]
568704007929	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
568704007930	PTS system sorbose-specific iic component; Region: EII-Sor; pfam03609
568704007931	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
568704007932	putative catalytic site [active]
568704007933	putative metal binding site [ion binding]; other site
568704007934	putative phosphate binding site [ion binding]; other site
568704007935	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
568704007936	DHH family; Region: DHH; pfam01368
568704007937	DHHA1 domain; Region: DHHA1; pfam02272
568704007938	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
568704007939	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
568704007940	active site
568704007941	catalytic tetrad [active]
568704007942	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
568704007943	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
568704007944	DNA binding residues [nucleotide binding]
568704007945	putative dimer interface [polypeptide binding]; other site
568704007946	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
568704007947	Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002
568704007948	SpoVT / AbrB like domain; Region: SpoVT_AbrB; smart00966
568704007949	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
568704007950	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
568704007951	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568704007952	Walker A/P-loop; other site
568704007953	ATP binding site [chemical binding]; other site
568704007954	Q-loop/lid; other site
568704007955	ABC transporter signature motif; other site
568704007956	Walker B; other site
568704007957	D-loop; other site
568704007958	H-loop/switch region; other site
568704007959	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
568704007960	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
568704007961	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568704007962	Coenzyme A binding pocket [chemical binding]; other site
568704007963	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
568704007964	D,D-heptose 1,7-bisphosphate phosphatase; Validated; Region: PRK08942
568704007965	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568704007966	active site
568704007967	motif I; other site
568704007968	motif II; other site
568704007969	Tyrosine phosphatase family; Region: Y_phosphatase3; pfam13350
568704007970	Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; Region: PTPc; cl00053
568704007971	Tyrosine phosphatase family C-terminal region; Region: Y_phosphatase3C; pfam13348
568704007972	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
568704007973	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568704007974	Coenzyme A binding pocket [chemical binding]; other site
568704007975	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
568704007976	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
568704007977	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
568704007978	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
568704007979	transmembrane helices; other site
568704007980	hypothetical protein; Provisional; Region: PRK11281
568704007981	Uncharacterized M20 Dipeptidases; Region: M20_dipept_like_4; cd05681
568704007982	hypothetical protein; Provisional; Region: PRK06446
568704007983	metal binding site [ion binding]; metal-binding site
568704007984	dimer interface [polypeptide binding]; other site
568704007985	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
568704007986	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
568704007987	peptide binding site [polypeptide binding]; other site
568704007988	Glycosyl hydrolase family 43; Region: GH43_6; cd08985
568704007989	active site
568704007990	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
568704007991	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
568704007992	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568704007993	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
568704007994	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704007995	putative substrate translocation pore; other site
568704007996	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
568704007997	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
568704007998	Soluble P-type ATPase [General function prediction only]; Region: COG4087
568704007999	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
568704008000	Group of bacterial proteins containing an alpha crystallin domain (ACD) similar to Lactobacillus plantarum (Lp) small heat shock proteins (sHsp) HSP 18.5, HSP 18.55 and HSP 19.3. sHsps are molecular chaperones that suppress protein aggregation and...; Region: ACD_LpsHSP_like; cd06471
568704008001	putative dimer interface [polypeptide binding]; other site
568704008002	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
568704008003	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
568704008004	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
568704008005	protein binding site [polypeptide binding]; other site
568704008006	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
568704008007	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
568704008008	YycH protein; Region: YycI; pfam09648
568704008009	YycH protein; Region: YycH; pfam07435
568704008010	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4863
568704008011	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: VicK; COG5002
568704008012	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
568704008013	dimerization interface [polypeptide binding]; other site
568704008014	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
568704008015	putative active site [active]
568704008016	heme pocket [chemical binding]; other site
568704008017	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
568704008018	dimer interface [polypeptide binding]; other site
568704008019	phosphorylation site [posttranslational modification]
568704008020	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568704008021	ATP binding site [chemical binding]; other site
568704008022	Mg2+ binding site [ion binding]; other site
568704008023	G-X-G motif; other site
568704008024	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
568704008025	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568704008026	active site
568704008027	phosphorylation site [posttranslational modification]
568704008028	intermolecular recognition site; other site
568704008029	dimerization interface [polypeptide binding]; other site
568704008030	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
568704008031	DNA binding site [nucleotide binding]
568704008032	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
568704008033	Novel bacterial esterase that cleaves esters on halogenated cyclic compounds; Region: Esterase_713_like; cl17303
568704008034	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
568704008035	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
568704008036	substrate binding pocket [chemical binding]; other site
568704008037	membrane-bound complex binding site; other site
568704008038	hinge residues; other site
568704008039	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
568704008040	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568704008041	dimer interface [polypeptide binding]; other site
568704008042	conserved gate region; other site
568704008043	putative PBP binding loops; other site
568704008044	ABC-ATPase subunit interface; other site
568704008045	argininosuccinate synthase; Provisional; Region: PRK13820
568704008046	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
568704008047	ANP binding site [chemical binding]; other site
568704008048	Substrate Binding Site II [chemical binding]; other site
568704008049	Substrate Binding Site I [chemical binding]; other site
568704008050	argininosuccinate lyase; Provisional; Region: PRK00855
568704008051	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
568704008052	active sites [active]
568704008053	tetramer interface [polypeptide binding]; other site
568704008054	Uncharacterized conserved protein [Function unknown]; Region: COG3589
568704008055	Bacterial protein of unknown function (DUF871); Region: DUF871; pfam05913
568704008056	Domain of unknown function (DUF3284); Region: DUF3284; pfam11687
568704008057	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
568704008058	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
568704008059	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
568704008060	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568704008061	DNA-binding site [nucleotide binding]; DNA binding site
568704008062	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
568704008063	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
568704008064	active site
568704008065	P-loop; other site
568704008066	phosphorylation site [posttranslational modification]
568704008067	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
568704008068	active site
568704008069	methionine cluster; other site
568704008070	phosphorylation site [posttranslational modification]
568704008071	metal binding site [ion binding]; metal-binding site
568704008072	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
568704008073	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
568704008074	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_18; cd04677
568704008075	nudix motif; other site
568704008076	hypothetical protein; Provisional; Region: PRK06762
568704008077	AAA domain; Region: AAA_33; pfam13671
568704008078	Isochorismatase family; Region: Isochorismatase; pfam00857
568704008079	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
568704008080	catalytic triad [active]
568704008081	dimer interface [polypeptide binding]; other site
568704008082	conserved cis-peptide bond; other site
568704008083	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568704008084	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
568704008085	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cl17904
568704008086	Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807
568704008087	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cl17904
568704008088	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
568704008089	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
568704008090	active site
568704008091	catalytic tetrad [active]
568704008092	Domain of unknown function (DUF956); Region: DUF956; pfam06115
568704008093	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
568704008094	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
568704008095	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cl00021
568704008096	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
568704008097	active pocket/dimerization site; other site
568704008098	active site
568704008099	phosphorylation site [posttranslational modification]
568704008100	PTS system sorbose subfamily IIB component; Region: PTSIIB_sorb; pfam03830
568704008101	active site
568704008102	phosphorylation site [posttranslational modification]
568704008103	H+ Antiporter protein; Region: 2A0121; TIGR00900
568704008104	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568704008105	non-specific DNA binding site [nucleotide binding]; other site
568704008106	salt bridge; other site
568704008107	sequence-specific DNA binding site [nucleotide binding]; other site
568704008108	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
568704008109	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568704008110	non-specific DNA binding site [nucleotide binding]; other site
568704008111	salt bridge; other site
568704008112	sequence-specific DNA binding site [nucleotide binding]; other site
568704008113	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
568704008114	BacA is a bacterial lysin from Enterococcus faecalis that degrades bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues. BacA is homologous to the YbfG and YkuG lysins of...; Region: GH25_BacA-like; cd06418
568704008115	active site
568704008116	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
568704008117	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
568704008118	substrate binding pocket [chemical binding]; other site
568704008119	membrane-bound complex binding site; other site
568704008120	hinge residues; other site
568704008121	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
568704008122	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568704008123	dimer interface [polypeptide binding]; other site
568704008124	conserved gate region; other site
568704008125	putative PBP binding loops; other site
568704008126	ABC-ATPase subunit interface; other site
568704008127	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
568704008128	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
568704008129	Walker A/P-loop; other site
568704008130	ATP binding site [chemical binding]; other site
568704008131	Q-loop/lid; other site
568704008132	ABC transporter signature motif; other site
568704008133	Walker B; other site
568704008134	D-loop; other site
568704008135	H-loop/switch region; other site
568704008136	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
568704008137	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
568704008138	Protein of unknown function (DUF975); Region: DUF975; cl10504
568704008139	Uncharacterized conserved protein [Function unknown]; Region: COG3402
568704008140	Predicted membrane protein [Function unknown]; Region: COG3428
568704008141	Bacterial PH domain; Region: DUF304; pfam03703
568704008142	Bacterial PH domain; Region: DUF304; pfam03703
568704008143	Predicted ATPase [General function prediction only]; Region: COG3910
568704008144	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
568704008145	Walker A/P-loop; other site
568704008146	ATP binding site [chemical binding]; other site
568704008147	Q-loop/lid; other site
568704008148	ABC transporter signature motif; other site
568704008149	Walker B; other site
568704008150	D-loop; other site
568704008151	H-loop/switch region; other site
568704008152	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3001
568704008153	Phosphotransferase enzyme family; Region: APH; pfam01636
568704008154	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
568704008155	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
568704008156	Walker A/P-loop; other site
568704008157	ATP binding site [chemical binding]; other site
568704008158	Q-loop/lid; other site
568704008159	ABC transporter signature motif; other site
568704008160	Walker B; other site
568704008161	D-loop; other site
568704008162	H-loop/switch region; other site
568704008163	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
568704008164	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
568704008165	substrate binding pocket [chemical binding]; other site
568704008166	membrane-bound complex binding site; other site
568704008167	hinge residues; other site
568704008168	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568704008169	dimer interface [polypeptide binding]; other site
568704008170	conserved gate region; other site
568704008171	putative PBP binding loops; other site
568704008172	ABC-ATPase subunit interface; other site
568704008173	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
568704008174	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
568704008175	substrate binding pocket [chemical binding]; other site
568704008176	membrane-bound complex binding site; other site
568704008177	hinge residues; other site
568704008178	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
568704008179	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568704008180	dimer interface [polypeptide binding]; other site
568704008181	conserved gate region; other site
568704008182	putative PBP binding loops; other site
568704008183	ABC-ATPase subunit interface; other site
568704008184	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
568704008185	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
568704008186	Integral membrane protein DUF95; Region: DUF95; pfam01944
568704008187	MoxR-like ATPases [General function prediction only]; Region: COG0714
568704008188	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568704008189	Walker A motif; other site
568704008190	ATP binding site [chemical binding]; other site
568704008191	Walker B motif; other site
568704008192	arginine finger; other site
568704008193	Protein of unknown function DUF58; Region: DUF58; pfam01882
568704008194	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
568704008195	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
568704008196	This family is most closely related to the GT1 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be...; Region: GT1_amsD_like; cd03820
568704008197	putative ADP-binding pocket [chemical binding]; other site
568704008198	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
568704008199	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
568704008200	Aspartase; Region: Aspartase; cd01357
568704008201	active sites [active]
568704008202	tetramer interface [polypeptide binding]; other site
568704008203	Malic enzyme [Energy production and conversion]; Region: SfcA; COG0281
568704008204	Malic enzyme, N-terminal domain; Region: malic; pfam00390
568704008205	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
568704008206	putative NAD(P) binding site [chemical binding]; other site
568704008207	2-hydroxycarboxylate transporter family; Region: 2HCT; pfam03390
568704008208	PAS domain S-box; Region: sensory_box; TIGR00229
568704008209	PAS domain; Region: PAS; smart00091
568704008210	putative active site [active]
568704008211	heme pocket [chemical binding]; other site
568704008212	Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms]; Region: CitB; COG4565
568704008213	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568704008214	active site
568704008215	phosphorylation site [posttranslational modification]
568704008216	intermolecular recognition site; other site
568704008217	dimerization interface [polypeptide binding]; other site
568704008218	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
568704008219	Herpesviridae UL52/UL70 DNA primase; Region: Herpes_UL52; cl17300
568704008220	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
568704008221	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_4; cd12162
568704008222	putative ligand binding site [chemical binding]; other site
568704008223	putative NAD binding site [chemical binding]; other site
568704008224	catalytic site [active]
568704008225	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
568704008226	NAD binding domain of 6-phosphogluconate dehydrogenase; Region: NAD_binding_2; pfam03446
568704008227	GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518
568704008228	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
568704008229	catalytic triad [active]
568704008230	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
568704008231	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
568704008232	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
568704008233	active site
568704008234	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
568704008235	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
568704008236	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
568704008237	Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657
568704008238	substrate binding pocket [chemical binding]; other site
568704008239	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
568704008240	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
568704008241	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
568704008242	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
568704008243	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
568704008244	active site
568704008245	phosphorylation site [posttranslational modification]
568704008246	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
568704008247	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
568704008248	DNA-binding interface [nucleotide binding]; DNA binding site
568704008249	PRD domain; Region: PRD; pfam00874
568704008250	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
568704008251	active site
568704008252	P-loop; other site
568704008253	phosphorylation site [posttranslational modification]
568704008254	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cl00163
568704008255	active site
568704008256	phosphorylation site [posttranslational modification]
568704008257	Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism]; Region: MtlA; COG2213
568704008258	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
568704008259	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
568704008260	active site
568704008261	P-loop; other site
568704008262	phosphorylation site [posttranslational modification]
568704008263	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
568704008264	active site
568704008265	P-loop; other site
568704008266	phosphorylation site [posttranslational modification]
568704008267	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
568704008268	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
568704008269	active site
568704008270	trimer interface [polypeptide binding]; other site
568704008271	allosteric site; other site
568704008272	active site lid [active]
568704008273	hexamer (dimer of trimers) interface [polypeptide binding]; other site
568704008274	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568704008275	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
568704008276	active site
568704008277	motif I; other site
568704008278	motif II; other site
568704008279	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
568704008280	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568704008281	non-specific DNA binding site [nucleotide binding]; other site
568704008282	salt bridge; other site
568704008283	sequence-specific DNA binding site [nucleotide binding]; other site
568704008284	Predicted Zn peptidase [Amino acid transport and metabolism]; Region: COG2856
568704008285	HlyD family secretion protein; Region: HlyD_2; pfam12700
568704008286	HlyD family secretion protein; Region: HlyD_3; pfam13437
568704008287	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
568704008288	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
568704008289	Walker A/P-loop; other site
568704008290	ATP binding site [chemical binding]; other site
568704008291	Q-loop/lid; other site
568704008292	ABC transporter signature motif; other site
568704008293	Walker B; other site
568704008294	D-loop; other site
568704008295	H-loop/switch region; other site
568704008296	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
568704008297	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
568704008298	FtsX-like permease family; Region: FtsX; pfam02687
568704008299	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
568704008300	alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases; Region: MDR_like_2; cd05289
568704008301	putative NAD(P) binding site [chemical binding]; other site
568704008302	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
568704008303	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568704008304	non-specific DNA binding site [nucleotide binding]; other site
568704008305	salt bridge; other site
568704008306	sequence-specific DNA binding site [nucleotide binding]; other site
568704008307	Polyketide cyclase / dehydrase and lipid transport; Region: Polyketide_cyc2; pfam10604
568704008308	hydrophobic ligand binding site; other site
568704008309	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
568704008310	KxYKxGKxW signal peptide; Region: KxYKxGKxW; TIGR03715
568704008311	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
568704008312	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
568704008313	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
568704008314	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
568704008315	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
568704008316	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
568704008317	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
568704008318	transaminase; Reviewed; Region: PRK08068
568704008319	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
568704008320	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568704008321	homodimer interface [polypeptide binding]; other site
568704008322	catalytic residue [active]
568704008323	Predicted amidohydrolase [General function prediction only]; Region: COG0388
568704008324	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_5; cd07583
568704008325	putative active site [active]
568704008326	catalytic triad [active]
568704008327	putative dimer interface [polypeptide binding]; other site
568704008328	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
568704008329	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
568704008330	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
568704008331	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
568704008332	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
568704008333	putative active site [active]
568704008334	metal binding site [ion binding]; metal-binding site
568704008335	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
568704008336	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
568704008337	metal binding site [ion binding]; metal-binding site
568704008338	dimer interface [polypeptide binding]; other site
568704008339	Protein of unknown function (DUF3815); Region: DUF3815; pfam12821
568704008340	Uncharacterized conserved protein [Function unknown]; Region: COG2966
568704008341	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
568704008342	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
568704008343	Walker A/P-loop; other site
568704008344	ATP binding site [chemical binding]; other site
568704008345	ABC transporter; Region: ABC_tran; pfam00005
568704008346	Q-loop/lid; other site
568704008347	ABC transporter signature motif; other site
568704008348	Walker B; other site
568704008349	D-loop; other site
568704008350	H-loop/switch region; other site
568704008351	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
568704008352	tRNA:m(5)U-54 methyltransferase; Region: gid_trmFO; TIGR00137
568704008353	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
568704008354	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
568704008355	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
568704008356	trmE is a tRNA modification GTPase; Region: trmE; cd04164
568704008357	G1 box; other site
568704008358	GTP/Mg2+ binding site [chemical binding]; other site
568704008359	Switch I region; other site
568704008360	G2 box; other site
568704008361	Switch II region; other site
568704008362	G3 box; other site
568704008363	G4 box; other site
568704008364	G5 box; other site
568704008365	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
568704008366	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
568704008367	jag_K homology RNA-binding domain. The KH domain is found in proteins homologous to the Bacillus subtilis protein Jag, which is associated with SpoIIIJ and is necessary for the third stage of sporulation.  The KH motif is a beta-alpha-alpha-beta-beta...; Region: jag_KH; cd02414
568704008368	G-X-X-G motif; other site
568704008369	R3H domain found in proteins homologous to Bacillus subtilus Jag, which is associated with SpoIIIJ. SpoIIIJ is necessary for the third stage of sporulation. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine...; Region: R3H_jag; cd02644
568704008370	RxxxH motif; other site
568704008371	Preprotein translocase subunit YidC [Intracellular trafficking and secretion]; Region: YidC; COG0706
568704008372	60Kd inner membrane protein; Region: 60KD_IMP; cl00489
568704008373	ribonuclease P; Reviewed; Region: rnpA; PRK00499
568704008374	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
568704008375	Replication initiator protein A (RepA) N-terminus; Region: RepA_N; pfam06970
568704008376	Cna protein B-type domain; Region: Cna_B; pfam05738
568704008377	Cna protein B-type domain; Region: Cna_B; pfam05738
568704008378	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
568704008379	chromosome segregation protein SMC, primarily archaeal type; Region: SMC_prok_A; TIGR02169
568704008380	Antirestriction protein [DNA replication, recombination, and repair]; Region: COG4227
568704008381	Peptidase MA superfamily; Region: Peptidase_MA_2; pfam13485
568704008382	Protein of unknown function (DUF3991); Region: DUF3991; pfam13154
568704008383	Toprim-like; Region: Toprim_2; pfam13155
568704008384	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
568704008385	Transposase; Region: DEDD_Tnp_IS110; pfam01548
568704008386	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
568704008387	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
568704008388	Sortase A (SrtA) or subfamily-1 sortases are cysteine transpeptidases found in gram-positive bacteria that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. They do so by catalyzing a transpeptidation reaction in which the...; Region: Sortase_A_1; cd06165
568704008389	active site
568704008390	catalytic site [active]
568704008391	Transposase domain (DUF772); Region: DUF772; pfam05598
568704008392	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
568704008393	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
568704008394	HTH domain; Region: HTH_11; pfam08279
568704008395	HTH domain; Region: HTH_11; pfam08279
568704008396	PRD domain; Region: PRD; pfam00874
568704008397	PRD domain; Region: PRD; pfam00874
568704008398	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
568704008399	active site
568704008400	P-loop; other site
568704008401	phosphorylation site [posttranslational modification]
568704008402	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
568704008403	active site
568704008404	phosphorylation site [posttranslational modification]
568704008405	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
568704008406	active site
568704008407	phosphorylation site [posttranslational modification]
568704008408	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
568704008409	active site
568704008410	P-loop; other site
568704008411	phosphorylation site [posttranslational modification]
568704008412	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
568704008413	alpha-mannosidase; Provisional; Region: PRK09819
568704008414	N-terminal catalytic domain of Escherichia coli alpha-mannosidase MngB and its bacterial homologs; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_EcMngB_like; cd10815
568704008415	active site
568704008416	metal binding site [ion binding]; metal-binding site
568704008417	catalytic site [active]
568704008418	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; cl08536
568704008419	RhaT L-rhamnose-proton symporter family protein; Region: RhaT; TIGR00776
568704008420	potential frameshift: common BLAST hit: gi|191638893|ref|YP_001988059.1| Putative uncharacterized protein orf-192
568704008421	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
568704008422	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
568704008423	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
568704008424	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
568704008425	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
568704008426	HsdM N-terminal domain; Region: HsdM_N; pfam12161
568704008427	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
568704008428	Methyltransferase domain; Region: Methyltransf_26; pfam13659
568704008429	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
568704008430	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
568704008431	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
568704008432	ATP binding site [chemical binding]; other site
568704008433	putative Mg++ binding site [ion binding]; other site
568704008434	Helix-turn-helix domain; Region: HTH_38; pfam13936
568704008435	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
568704008436	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
568704008437	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
568704008438	dimer interface [polypeptide binding]; other site
568704008439	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568704008440	catalytic residue [active]
568704008441	cystathionine beta-lyase; Provisional; Region: PRK07671
568704008442	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
568704008443	homodimer interface [polypeptide binding]; other site
568704008444	substrate-cofactor binding pocket; other site
568704008445	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568704008446	catalytic residue [active]
568704008447	serine O-acetyltransferase; Region: cysE; TIGR01172
568704008448	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
568704008449	trimer interface [polypeptide binding]; other site
568704008450	active site
568704008451	substrate binding site [chemical binding]; other site
568704008452	CoA binding site [chemical binding]; other site
568704008453	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
568704008454	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
568704008455	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
568704008456	Putative glucose uptake permease [Carbohydrate transport and metabolism]; Region: GlcU; COG4975
568704008457	Putative rRNA methylase; Region: rRNA_methylase; pfam06962
568704008458	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
568704008459	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
568704008460	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
568704008461	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
568704008462	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
568704008463	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
568704008464	Melibiase; Region: Melibiase; pfam02065
568704008465	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
568704008466	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
568704008467	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
568704008468	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
568704008469	active site
568704008470	DNA binding site [nucleotide binding]
568704008471	pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK07251
568704008472	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
568704008473	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
568704008474	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
568704008475	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
568704008476	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
568704008477	potential frameshift: common BLAST hit: gi|116326665|ref|YP_796439.1| transposase
568704008478	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
568704008479	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
568704008480	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
568704008481	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
568704008482	active site
568704008483	CAT RNA binding domain; Region: CAT_RBD; pfam03123
568704008484	transcriptional antiterminator BglG; Provisional; Region: PRK09772
568704008485	PRD domain; Region: PRD; pfam00874
568704008486	PRD domain; Region: PRD; pfam00874
568704008487	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; cl17295
568704008488	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
568704008489	PTS_IIB_lactose: subunit IIB of enzyme II (EII) of the lactose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS) found in Firmicutes as well as Actinobacteria. In this system, EII is a lactose-specific permease with two...; Region: PTS_IIB_lactose; cd05565
568704008490	active site
568704008491	P-loop; other site
568704008492	phosphorylation site [posttranslational modification]
568704008493	6-phospho-beta-galactosidase; Region: lacG; TIGR01233
568704008494	beta-galactosidase; Region: BGL; TIGR03356
568704008495	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
568704008496	methionine cluster; other site
568704008497	active site
568704008498	phosphorylation site [posttranslational modification]
568704008499	metal binding site [ion binding]; metal-binding site
568704008500	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
568704008501	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
568704008502	potential frameshift: common BLAST hit: gi|203284763|ref|YP_002221607.1| transposase
568704008503	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
568704008504	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
568704008505	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
568704008506	Dimer interface [polypeptide binding]; other site
568704008507	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
568704008508	multiple promoter invertase; Provisional; Region: mpi; PRK13413
568704008509	catalytic residues [active]
568704008510	catalytic nucleophile [active]
568704008511	Presynaptic Site I dimer interface [polypeptide binding]; other site
568704008512	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
568704008513	Synaptic Flat tetramer interface [polypeptide binding]; other site
568704008514	Synaptic Site I dimer interface [polypeptide binding]; other site
568704008515	DNA binding site [nucleotide binding]
568704008516	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
568704008517	Helix-turn-helix domain; Region: HTH_38; pfam13936
568704008518	Integrase core domain; Region: rve; pfam00665
568704008519	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
568704008520	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
568704008521	DNA polymerase IV; Reviewed; Region: PRK03103
568704008522	DNA polymerase IV; Reviewed; Region: PRK03103
568704008523	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
568704008524	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
568704008525	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586