-- dump date   	20140619_125538
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
929102000001	Protein involved in initiation of plasmid replication [DNA replication, recombination, and repair]; Region: COG5527
929102000002	Initiator Replication protein; Region: Rep_3; pfam01051
929102000003	Lactococcus lactis RepB C-terminus; Region: L_lactis_RepB_C; pfam06430
929102000004	RNA polymerase sigma factor; Provisional; Region: PRK05901
929102000005	Domain of unknown function (DUF4145); Region: DUF4145; pfam13643
929102000006	DEAD-like helicases superfamily; Region: DEXDc; smart00487
929102000007	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
929102000008	ATP binding site [chemical binding]; other site
929102000009	putative Mg++ binding site [ion binding]; other site
929102000010	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
929102000011	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929102000012	Coenzyme A binding pocket [chemical binding]; other site
929102000013	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4487
929102000014	Uncharacterized protein conserved in bacteria (DUF2130); Region: DUF2130; pfam09903
929102000015	PHP-associated; Region: PHP_C; pfam13263
929102000016	AAA domain; Region: AAA_21; pfam13304
929102000017	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; cl17405
929102000018	multiple promoter invertase; Provisional; Region: mpi; PRK13413
929102000019	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
929102000020	catalytic residues [active]
929102000021	catalytic nucleophile [active]
929102000022	Presynaptic Site I dimer interface [polypeptide binding]; other site
929102000023	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
929102000024	Synaptic Flat tetramer interface [polypeptide binding]; other site
929102000025	Synaptic Site I dimer interface [polypeptide binding]; other site
929102000026	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
929102000027	DNA-binding interface [nucleotide binding]; DNA binding site
929102000028	recombinase A; Provisional; Region: recA; PRK09354
929102000029	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
929102000030	hexamer interface [polypeptide binding]; other site
929102000031	Walker A motif; other site
929102000032	ATP binding site [chemical binding]; other site
929102000033	Walker B motif; other site
929102000034	DNA polymerase IV; Reviewed; Region: PRK03103
929102000035	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
929102000036	active site
929102000037	DNA binding site [nucleotide binding]
929102000038	Toxin ToxN, type III toxin-antitoxin system; Region: ToxN_toxin; pfam13958
929102000039	Sortases are cysteine transpeptidases, found in gram-positive bacteria, that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. They do so by catalyzing a transpeptidation reaction in which the surface protein substrate is...; Region: Sortase; cl09098
929102000040	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
929102000041	Walker A motif; other site
929102000042	ATP binding site [chemical binding]; other site
929102000043	MepB protein; Region: MepB; pfam08877
929102000044	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
929102000045	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
929102000046	catalytic residues [active]
929102000047	catalytic nucleophile [active]
929102000048	Presynaptic Site I dimer interface [polypeptide binding]; other site
929102000049	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
929102000050	Synaptic Flat tetramer interface [polypeptide binding]; other site
929102000051	Synaptic Site I dimer interface [polypeptide binding]; other site
929102000052	DNA binding site [nucleotide binding]
929102000053	Domain of unknown function (DUF4158); Region: DUF4158; pfam13700
929102000054	Tn3 transposase DDE domain; Region: DDE_Tnp_Tn3; pfam01526
929102000055	PrgI family protein; Region: PrgI; pfam12666
929102000056	AAA-like domain; Region: AAA_10; pfam12846
929102000057	Domain of unknown function DUF87; Region: DUF87; pfam01935
929102000058	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; pfam01832
929102000059	CHAP domain; Region: CHAP; pfam05257
929102000060	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
929102000061	catalytic residues [active]
929102000062	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
929102000063	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
929102000064	Bacterial mobilisation protein (MobC); Region: MobC; pfam05713
929102000065	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
929102000066	Protein involved in initiation of plasmid replication [DNA replication, recombination, and repair]; Region: COG5527
929102000067	Initiator Replication protein; Region: Rep_3; pfam01051
929102000068	Lactococcus lactis RepB C-terminus; Region: L_lactis_RepB_C; pfam06430
929102000069	alpha-ketoglutarate decarboxylase; Reviewed; Region: kgd; PRK12270
929102000070	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
929102000071	Bacterial mobilisation protein (MobC); Region: MobC; pfam05713
929102000072	Antirestriction protein [DNA replication, recombination, and repair]; Region: COG4227
929102000073	Domain of unknown function (DUF955); Region: DUF955; cl01076
929102000074	Seryl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: SerS; COG0172
929102000075	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
929102000076	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
929102000077	catalytic residues [active]
929102000078	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; pfam01832
929102000079	CHAP domain; Region: CHAP; pfam05257
929102000080	MepB protein; Region: MepB; pfam08877
929102000081	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
929102000082	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
929102000083	catalytic residues [active]
929102000084	catalytic nucleophile [active]
929102000085	Presynaptic Site I dimer interface [polypeptide binding]; other site
929102000086	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
929102000087	Synaptic Flat tetramer interface [polypeptide binding]; other site
929102000088	Synaptic Site I dimer interface [polypeptide binding]; other site
929102000089	DNA binding site [nucleotide binding]
929102000090	Domain of unknown function (DUF4158); Region: DUF4158; pfam13700
929102000091	Tn3 transposase DDE domain; Region: DDE_Tnp_Tn3; pfam01526
929102000092	copper-(or silver)-translocating P-type ATPase; Region: ATPase-IB1_Cu; TIGR01511
929102000093	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
929102000094	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
929102000095	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3316
929102000096	Integrase core domain; Region: rve; pfam00665
929102000097	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
929102000098	active site
929102000099	DNA binding site [nucleotide binding]
929102000100	Int/Topo IB signature motif; other site
929102000101	Domain of unknown function (DUF4298); Region: DUF4298; pfam14131
929102000102	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
929102000103	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929102000104	non-specific DNA binding site [nucleotide binding]; other site
929102000105	salt bridge; other site
929102000106	sequence-specific DNA binding site [nucleotide binding]; other site
929102000107	Helix-turn-helix domain; Region: HTH_17; pfam12728
929102000108	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
929102000109	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
929102000110	Methyltransferase domain; Region: Methyltransf_26; pfam13659
929102000111	Protein involved in initiation of plasmid replication [DNA replication, recombination, and repair]; Region: COG5527
929102000112	Initiator Replication protein; Region: Rep_3; pfam01051
929102000113	Lactococcus lactis RepB C-terminus; Region: L_lactis_RepB_C; pfam06430
929102000114	HTH DNA binding domain; Region: HTH_10; pfam04967
929102000115	phosphodiesterase; Provisional; Region: PRK12704
929102000116	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cl00364
929102000117	L11 interface [polypeptide binding]; other site
929102000118	putative EF-Tu interaction site [polypeptide binding]; other site
929102000119	putative EF-G interaction site [polypeptide binding]; other site
929102000120	Integral membrane protein DUF95; Region: DUF95; pfam01944
929102000121	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
929102000122	active site
929102000123	DNA binding site [nucleotide binding]
929102000124	Int/Topo IB signature motif; other site
929102000125	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
929102000126	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929102000127	Walker A motif; other site
929102000128	ATP binding site [chemical binding]; other site
929102000129	Walker B motif; other site
929102000130	arginine finger; other site
929102000131	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
929102000132	DnaA box-binding interface [nucleotide binding]; other site
929102000133	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
929102000134	DNA polymerase III beta subunit; Region: POL3Bc; smart00480
929102000135	putative DNA binding surface [nucleotide binding]; other site
929102000136	dimer interface [polypeptide binding]; other site
929102000137	beta-clamp/clamp loader binding surface; other site
929102000138	beta-clamp/translesion DNA polymerase binding surface; other site
929102000139	ATP-dependent nuclease, subunit B [DNA replication, recombination, and repair]; Region: AddB; COG3857
929102000140	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
929102000141	helicase-exonuclease AddAB, AddA subunit, Firmicutes type; Region: addA_Gpos; TIGR02785
929102000142	Part of AAA domain; Region: AAA_19; pfam13245
929102000143	Family description; Region: UvrD_C_2; pfam13538
929102000144	Bacterial protein of unknown function (DUF951); Region: DUF951; pfam06107
929102000145	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
929102000146	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929102000147	non-specific DNA binding site [nucleotide binding]; other site
929102000148	salt bridge; other site
929102000149	sequence-specific DNA binding site [nucleotide binding]; other site
929102000150	GTP-binding protein YchF; Reviewed; Region: PRK09601
929102000151	YchF GTPase; Region: YchF; cd01900
929102000152	G1 box; other site
929102000153	GTP/Mg2+ binding site [chemical binding]; other site
929102000154	Switch I region; other site
929102000155	G2 box; other site
929102000156	Switch II region; other site
929102000157	G3 box; other site
929102000158	G4 box; other site
929102000159	G5 box; other site
929102000160	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
929102000161	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929102000162	non-specific DNA binding site [nucleotide binding]; other site
929102000163	salt bridge; other site
929102000164	sequence-specific DNA binding site [nucleotide binding]; other site
929102000165	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4652
929102000166	FtsX-like permease family; Region: FtsX; pfam02687
929102000167	Protein of unknown function (DUF1430); Region: DUF1430; pfam07242
929102000168	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
929102000169	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
929102000170	Walker A/P-loop; other site
929102000171	ATP binding site [chemical binding]; other site
929102000172	Q-loop/lid; other site
929102000173	ABC transporter signature motif; other site
929102000174	Walker B; other site
929102000175	D-loop; other site
929102000176	H-loop/switch region; other site
929102000177	Adenylate kinase and related kinases [Nucleotide transport and metabolism]; Region: Adk; COG0563
929102000178	AAA domain; Region: AAA_17; pfam13207
929102000179	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
929102000180	putative active site [active]
929102000181	catalytic residue [active]
929102000182	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
929102000183	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
929102000184	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
929102000185	ATP binding site [chemical binding]; other site
929102000186	putative Mg++ binding site [ion binding]; other site
929102000187	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
929102000188	nucleotide binding region [chemical binding]; other site
929102000189	ATP-binding site [chemical binding]; other site
929102000190	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
929102000191	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
929102000192	RNA binding surface [nucleotide binding]; other site
929102000193	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
929102000194	Septum formation initiator; Region: DivIC; cl17659
929102000195	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
929102000196	RNA binding site [nucleotide binding]; other site
929102000197	Beta-lactamase class A [Defense mechanisms]; Region: PenP; COG2367
929102000198	SH3-like domain; Region: SH3_8; pfam13457
929102000199	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
929102000200	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
929102000201	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
929102000202	Ligand Binding Site [chemical binding]; other site
929102000203	TilS substrate C-terminal domain; Region: TilS_C; smart00977
929102000204	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
929102000205	active site
929102000206	ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones]; Region: HflB; COG0465
929102000207	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929102000208	Walker A motif; other site
929102000209	ATP binding site [chemical binding]; other site
929102000210	Walker B motif; other site
929102000211	arginine finger; other site
929102000212	Peptidase family M41; Region: Peptidase_M41; pfam01434
929102000213	Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism]; Region: MtlA; COG2213
929102000214	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
929102000215	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
929102000216	active site
929102000217	P-loop; other site
929102000218	phosphorylation site [posttranslational modification]
929102000219	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
929102000220	active site
929102000221	P-loop; other site
929102000222	phosphorylation site [posttranslational modification]
929102000223	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
929102000224	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
929102000225	PRD domain; Region: PRD; pfam00874
929102000226	PTS_IIB: subunit IIB of enzyme II (EII) is the central energy-coupling domain of the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In the multienzyme PTS complex, EII is a carbohydrate-specific permease consisting of two cytoplasmic...; Region: PTS_IIB; cl10014
929102000227	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
929102000228	active site
929102000229	phosphorylation site [posttranslational modification]
929102000230	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
929102000231	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
929102000232	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
929102000233	Phage terminase, small subunit [DNA replication, recombination, and repair]; Region: XtmA; COG3728
929102000234	Phage associated DNA primase [General function prediction only]; Region: COG3378
929102000235	D5 N terminal like; Region: D5_N; smart00885
929102000236	Poxvirus D5 protein-like; Region: Pox_D5; pfam03288
929102000237	Prim_Pol: Primase-polymerase (primpol) domain of the type found in bifunctional replicases from archaeal plasmids, including ORF904 protein of the crenarchaeal plasmid pRN1 from Sulfolobus islandicus (pRN1 primpol). These primpol domains belong to the...; Region: Prim_Pol; cd04859
929102000238	polymerase nucleotide-binding site; other site
929102000239	DNA-binding residues [nucleotide binding]; DNA binding site
929102000240	nucleotide binding site [chemical binding]; other site
929102000241	primase nucleotide-binding site [nucleotide binding]; other site
929102000242	Primase C terminal 1 (PriCT-1); Region: PriCT_1; smart00942
929102000243	Protein of unknown function (DUF1655); Region: DUF1655; pfam07868
929102000244	Uncharacterized phage-encoded protein [Function unknown]; Region: COG3646
929102000245	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
929102000246	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
929102000247	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929102000248	non-specific DNA binding site [nucleotide binding]; other site
929102000249	salt bridge; other site
929102000250	sequence-specific DNA binding site [nucleotide binding]; other site
929102000251	Enterocin A Immunity; Region: EntA_Immun; pfam08951
929102000252	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
929102000253	Int/Topo IB signature motif; other site
929102000254	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
929102000255	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929102000256	Coenzyme A binding pocket [chemical binding]; other site
929102000257	Predicted membrane protein [Function unknown]; Region: XynA; COG2314
929102000258	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
929102000259	Sulfate transporter family; Region: Sulfate_transp; pfam00916
929102000260	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
929102000261	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929102000262	Coenzyme A binding pocket [chemical binding]; other site
929102000263	aromatic amino acid aminotransferase; Validated; Region: PRK07309
929102000264	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
929102000265	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929102000266	homodimer interface [polypeptide binding]; other site
929102000267	catalytic residue [active]
929102000268	Recombination protein O N terminal; Region: RecO_N; pfam11967
929102000269	Recombinational DNA repair protein (RecF pathway) [DNA replication, recombination, and repair]; Region: RecO; COG1381
929102000270	Recombination protein O C terminal; Region: RecO_C; pfam02565
929102000271	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929102000272	non-specific DNA binding site [nucleotide binding]; other site
929102000273	salt bridge; other site
929102000274	sequence-specific DNA binding site [nucleotide binding]; other site
929102000275	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
929102000276	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
929102000277	FeS/SAM binding site; other site
929102000278	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
929102000279	MFS/sugar transport protein; Region: MFS_2; pfam13347
929102000280	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06416
929102000281	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
929102000282	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
929102000283	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
929102000284	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
929102000285	dihydrolipoamide acetyltransferase; Reviewed; Region: PRK11855
929102000286	E3 interaction surface; other site
929102000287	lipoyl attachment site [posttranslational modification]; other site
929102000288	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
929102000289	E3 interaction surface; other site
929102000290	lipoyl attachment site [posttranslational modification]; other site
929102000291	e3 binding domain; Region: E3_binding; pfam02817
929102000292	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
929102000293	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
929102000294	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
929102000295	TPP binding site [chemical binding]; other site
929102000296	alpha subunit interface [polypeptide binding]; other site
929102000297	heterodimer interface [polypeptide binding]; other site
929102000298	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
929102000299	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_x; TIGR03181
929102000300	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
929102000301	tetramer interface [polypeptide binding]; other site
929102000302	TPP-binding site [chemical binding]; other site
929102000303	heterodimer interface [polypeptide binding]; other site
929102000304	phosphorylation loop region [posttranslational modification]
929102000305	lipoyltransferase and lipoate-protein ligase; Region: lipoyltrans; TIGR00545
929102000306	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
929102000307	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
929102000308	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
929102000309	Glycerophosphodiester phosphodiesterase domain of Thermoanaerobacter tengcongensis and similar proteins; Region: GDPD_TtGDE_like; cd08563
929102000310	active site
929102000311	catalytic site [active]
929102000312	metal binding site [ion binding]; metal-binding site
929102000313	dimer interface [polypeptide binding]; other site
929102000314	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
929102000315	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
929102000316	Zn2+ binding site [ion binding]; other site
929102000317	Mg2+ binding site [ion binding]; other site
929102000318	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
929102000319	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
929102000320	active site
929102000321	HIGH motif; other site
929102000322	dimer interface [polypeptide binding]; other site
929102000323	KMSKS motif; other site
929102000324	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
929102000325	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
929102000326	putative phosphate acyltransferase; Provisional; Region: PRK05331
929102000327	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
929102000328	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
929102000329	active site
929102000330	motif I; other site
929102000331	motif II; other site
929102000332	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
929102000333	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
929102000334	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
929102000335	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
929102000336	ABC transporter; Region: ABC_tran_2; pfam12848
929102000337	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
929102000338	O-acetylhomoserine sulfhydrylase [Amino acid transport and metabolism]; Region: MET17; COG2873
929102000339	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
929102000340	homodimer interface [polypeptide binding]; other site
929102000341	substrate-cofactor binding pocket; other site
929102000342	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929102000343	catalytic residue [active]
929102000344	short chain dehydrogenase; Validated; Region: PRK06182
929102000345	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
929102000346	NADP binding site [chemical binding]; other site
929102000347	active site
929102000348	steroid binding site; other site
929102000349	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
929102000350	Ligand Binding Site [chemical binding]; other site
929102000351	Predicted esterase [General function prediction only]; Region: COG0400
929102000352	N-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_N_like; cd08346
929102000353	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
929102000354	Zn binding site [ion binding]; other site
929102000355	C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_C_like; cd08347
929102000356	Zn binding site [ion binding]; other site
929102000357	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
929102000358	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase; Region: CitX; cl01498
929102000359	Lactococcin-like family; Region: Lactococcin; pfam04369
929102000360	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
929102000361	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
929102000362	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
929102000363	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
929102000364	Soluble P-type ATPase [General function prediction only]; Region: COG4087
929102000365	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
929102000366	ParB-like nuclease domain; Region: ParBc; pfam02195
929102000367	KorB domain; Region: KorB; pfam08535
929102000368	ATPase related to the helicase subunit of the Holliday junction resolvase [DNA replication, recombination, and repair]; Region: MGS1; COG2256
929102000369	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929102000370	Walker A motif; other site
929102000371	ATP binding site [chemical binding]; other site
929102000372	Walker B motif; other site
929102000373	arginine finger; other site
929102000374	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
929102000375	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
929102000376	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929102000377	Coenzyme A binding pocket [chemical binding]; other site
929102000378	Protein of unknown function (DUF3013); Region: DUF3013; pfam11217
929102000379	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
929102000380	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929102000381	Walker A/P-loop; other site
929102000382	ATP binding site [chemical binding]; other site
929102000383	Q-loop/lid; other site
929102000384	ABC transporter signature motif; other site
929102000385	Walker B; other site
929102000386	D-loop; other site
929102000387	H-loop/switch region; other site
929102000388	ABC transporter; Region: ABC_tran_2; pfam12848
929102000389	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
929102000390	Bacteriocin-protection, YdeI or OmpD-Associated; Region: OmdA; pfam13376
929102000391	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
929102000392	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929102000393	S-adenosylmethionine binding site [chemical binding]; other site
929102000394	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
929102000395	RNA methyltransferase, RsmE family; Region: TIGR00046
929102000396	Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands; Region: CE4_NodB_like_5s_6s; cd10918
929102000397	putative active site [active]
929102000398	putative metal binding site [ion binding]; other site
929102000399	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
929102000400	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
929102000401	Zn2+ binding site [ion binding]; other site
929102000402	Mg2+ binding site [ion binding]; other site
929102000403	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
929102000404	synthetase active site [active]
929102000405	NTP binding site [chemical binding]; other site
929102000406	metal binding site [ion binding]; metal-binding site
929102000407	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
929102000408	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
929102000409	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
929102000410	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
929102000411	Ligand binding site; other site
929102000412	Putative Catalytic site; other site
929102000413	DXD motif; other site
929102000414	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
929102000415	putative active site [active]
929102000416	dimerization interface [polypeptide binding]; other site
929102000417	putative tRNAtyr binding site [nucleotide binding]; other site
929102000418	Predicted integral membrane protein [Function unknown]; Region: COG3548
929102000419	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
929102000420	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
929102000421	amino acid transporter; Region: 2A0306; TIGR00909
929102000422	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
929102000423	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
929102000424	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
929102000425	putative acyl-acceptor binding pocket; other site
929102000426	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
929102000427	MarR family; Region: MarR_2; cl17246
929102000428	Acyl carrier protein phosphodiesterase [Lipid metabolism]; Region: AcpD; COG1182
929102000429	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
929102000430	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
929102000431	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
929102000432	nucleotide binding region [chemical binding]; other site
929102000433	ATP-binding site [chemical binding]; other site
929102000434	SEC-C motif; Region: SEC-C; pfam02810
929102000435	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase [Amino acid transport and metabolism]; Region: AroG; COG0722
929102000436	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
929102000437	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
929102000438	dimerization domain swap beta strand [polypeptide binding]; other site
929102000439	regulatory protein interface [polypeptide binding]; other site
929102000440	active site
929102000441	regulatory phosphorylation site [posttranslational modification]; other site
929102000442	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
929102000443	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
929102000444	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
929102000445	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
929102000446	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG0718
929102000447	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
929102000448	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
929102000449	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
929102000450	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
929102000451	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929102000452	putative substrate translocation pore; other site
929102000453	argininosuccinate synthase; Provisional; Region: PRK13820
929102000454	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
929102000455	ANP binding site [chemical binding]; other site
929102000456	Substrate Binding Site II [chemical binding]; other site
929102000457	Substrate Binding Site I [chemical binding]; other site
929102000458	argininosuccinate lyase; Provisional; Region: PRK00855
929102000459	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
929102000460	active sites [active]
929102000461	tetramer interface [polypeptide binding]; other site
929102000462	drug efflux system protein MdtG; Provisional; Region: PRK09874
929102000463	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929102000464	putative substrate translocation pore; other site
929102000465	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
929102000466	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
929102000467	WHG domain; Region: WHG; pfam13305
929102000468	ribonuclease P; Reviewed; Region: rnpA; PRK00499
929102000469	Preprotein translocase subunit YidC [Intracellular trafficking and secretion]; Region: YidC; COG0706
929102000470	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
929102000471	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
929102000472	jag_K homology RNA-binding domain. The KH domain is found in proteins homologous to the Bacillus subtilis protein Jag, which is associated with SpoIIIJ and is necessary for the third stage of sporulation.  The KH motif is a beta-alpha-alpha-beta-beta...; Region: jag_KH; cd02414
929102000473	G-X-X-G motif; other site
929102000474	R3H domain. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. R3H domains are found in proteins together with ATPase domains, SF1 helicase domains, SF2 DEAH helicase domains, Cys-rich...; Region: R3H; cl00297
929102000475	RxxxH motif; other site
929102000476	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
929102000477	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
929102000478	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
929102000479	active site
929102000480	catalytic tetrad [active]
929102000481	hypothetical protein; Provisional; Region: PRK05473
929102000482	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
929102000483	hypothetical protein; Provisional; Region: PRK13678
929102000484	Predicted integral membrane protein [Function unknown]; Region: COG3548
929102000485	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
929102000486	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
929102000487	NAD(P) binding site [chemical binding]; other site
929102000488	active site
929102000489	Uncharacterized protein conserved in bacteria (DUF2316); Region: DUF2316; pfam10078
929102000490	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
929102000491	Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) [Cell envelope biogenesis, outer membrane]; Region: DltE; COG3967
929102000492	NAD(P) binding site [chemical binding]; other site
929102000493	active site
929102000494	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
929102000495	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
929102000496	putative DNA binding site [nucleotide binding]; other site
929102000497	putative Zn2+ binding site [ion binding]; other site
929102000498	glycogen branching enzyme; Provisional; Region: PRK12313
929102000499	Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus; Region: E_set; cl09101
929102000500	Alpha amylase catalytic domain found in bacterial and eukaryotic branching enzymes; Region: AmyAc_bac_euk_BE; cd11321
929102000501	active site
929102000502	catalytic site [active]
929102000503	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
929102000504	Predicted outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG4932
929102000505	Collagen binding domain; Region: Collagen_bind; pfam05737
929102000506	Collagen binding domain; Region: Collagen_bind; pfam05737
929102000507	Collagen binding domain; Region: Collagen_bind; pfam05737
929102000508	Cna protein B-type domain; Region: Cna_B; pfam05738
929102000509	Cna protein B-type domain; Region: Cna_B; pfam05738
929102000510	Predicted outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG4932
929102000511	Cna protein B-type domain; Region: Cna_B; pfam05738
929102000512	Cna protein B-type domain; Region: Cna_B; pfam05738
929102000513	Cna protein B-type domain; Region: Cna_B; pfam05738
929102000514	Cna protein B-type domain; Region: Cna_B; pfam05738
929102000515	Cna protein B-type domain; Region: Cna_B; pfam05738
929102000516	Cna protein B-type domain; Region: Cna_B; pfam05738
929102000517	Cna protein B-type domain; Region: Cna_B; pfam05738
929102000518	Gram positive anchor; Region: Gram_pos_anchor; pfam00746
929102000519	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
929102000520	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
929102000521	Protein of unknown function (DUF975); Region: DUF975; cl10504
929102000522	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929102000523	Major Facilitator Superfamily; Region: MFS_1; pfam07690
929102000524	putative substrate translocation pore; other site
929102000525	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
929102000526	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
929102000527	DNA/RNA non-specific endonuclease; Region: Endonuclea_NS_2; cl17626
929102000528	Cytochrome C biogenesis protein; Region: CcmH; cl01179
929102000529	aminotransferase AlaT; Validated; Region: PRK09265
929102000530	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
929102000531	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929102000532	homodimer interface [polypeptide binding]; other site
929102000533	catalytic residue [active]
929102000534	Pleiotropic transcriptional repressor [Transcription]; Region: CodY; COG4465
929102000535	CodY GAF-like domain; Region: CodY; pfam06018
929102000536	CodY helix-turn-helix domain; Region: HTH_CodY; pfam08222
929102000537	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit [Translation, ribosomal structure and biogenesis]; Region: GatC; COG0721
929102000538	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
929102000539	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
929102000540	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
929102000541	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
929102000542	GatB domain; Region: GatB_Yqey; pfam02637
929102000543	amidase; Provisional; Region: PRK06529
929102000544	Amidase; Region: Amidase; cl11426
929102000545	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; Region: MATE_yoeA_like; cd13138
929102000546	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
929102000547	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
929102000548	DNA-binding site [nucleotide binding]; DNA binding site
929102000549	RNA-binding motif; other site
929102000550	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
929102000551	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
929102000552	Rhomboid family; Region: Rhomboid; pfam01694
929102000553	Domain of unknown function (DUF3284); Region: DUF3284; pfam11687
929102000554	Predicted acetyltransferase involved in intracellular survival and related acetyltransferases [General function prediction only]; Region: Eis; COG4552
929102000555	Acetyltransferase (GNAT) domain; Region: Acetyltransf_9; pfam13527
929102000556	Uncharacterized conserved protein [Function unknown]; Region: COG3589
929102000557	Bacterial protein of unknown function (DUF871); Region: DUF871; pfam05913
929102000558	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
929102000559	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
929102000560	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
929102000561	beta-galactosidase; Region: BGL; TIGR03356
929102000562	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
929102000563	trimer interface [polypeptide binding]; other site
929102000564	active site
929102000565	Alpha/beta hydrolase of unknown function (DUF915); Region: DUF915; pfam06028
929102000566	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
929102000567	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
929102000568	active site
929102000569	metal binding site [ion binding]; metal-binding site
929102000570	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
929102000571	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4470
929102000572	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14455
929102000573	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
929102000574	FeS/SAM binding site; other site
929102000575	Nitroreductase-like family 1. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_1; cd02137
929102000576	dimer interface [polypeptide binding]; other site
929102000577	FMN binding site [chemical binding]; other site
929102000578	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
929102000579	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
929102000580	substrate binding pocket [chemical binding]; other site
929102000581	chain length determination region; other site
929102000582	substrate-Mg2+ binding site; other site
929102000583	catalytic residues [active]
929102000584	aspartate-rich region 1; other site
929102000585	active site lid residues [active]
929102000586	aspartate-rich region 2; other site
929102000587	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated; Region: PRK06080
929102000588	UbiA prenyltransferase family; Region: UbiA; pfam01040
929102000589	CAAX protease self-immunity; Region: Abi; pfam02517
929102000590	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
929102000591	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
929102000592	G1 box; other site
929102000593	GTP/Mg2+ binding site [chemical binding]; other site
929102000594	Switch I region; other site
929102000595	G2 box; other site
929102000596	G3 box; other site
929102000597	Switch II region; other site
929102000598	G4 box; other site
929102000599	G5 box; other site
929102000600	Nucleoside recognition; Region: Gate; pfam07670
929102000601	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
929102000602	Nucleoside recognition; Region: Gate; pfam07670
929102000603	FeoA domain; Region: FeoA; pfam04023
929102000604	Fe2+ transport system protein A [Inorganic ion transport and metabolism]; Region: FeoA; COG1918
929102000605	methionine sulfoxide reductase B; Provisional; Region: PRK00222
929102000606	SelR domain; Region: SelR; pfam01641
929102000607	Predicted kinase related to dihydroxyacetone kinase [General function prediction only]; Region: COG1461
929102000608	DAK2 domain; Region: Dak2; pfam02734
929102000609	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1302
929102000610	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
929102000611	Uncharacterized membrane-bound protein conserved in bacteria [Function unknown]; Region: COG4858
929102000612	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
929102000613	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
929102000614	substrate binding site; other site
929102000615	tetramer interface; other site
929102000616	dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfbC; COG1898
929102000617	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
929102000618	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
929102000619	NAD binding site [chemical binding]; other site
929102000620	substrate binding site [chemical binding]; other site
929102000621	homodimer interface [polypeptide binding]; other site
929102000622	active site
929102000623	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_19; cd07262
929102000624	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
929102000625	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
929102000626	RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321
929102000627	NADP binding site [chemical binding]; other site
929102000628	active site
929102000629	putative substrate binding site [chemical binding]; other site
929102000630	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
929102000631	This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_6; cd04955
929102000632	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_d; cd04196
929102000633	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
929102000634	Probable Catalytic site; other site
929102000635	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
929102000636	ABC-2 type transporter; Region: ABC2_membrane; cl17235
929102000637	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
929102000638	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
929102000639	Walker A/P-loop; other site
929102000640	ATP binding site [chemical binding]; other site
929102000641	Q-loop/lid; other site
929102000642	ABC transporter signature motif; other site
929102000643	Walker B; other site
929102000644	D-loop; other site
929102000645	H-loop/switch region; other site
929102000646	Predicted membrane protein (DUF2142); Region: DUF2142; pfam09913
929102000647	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
929102000648	active site
929102000649	Lipopolysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane]; Region: RgpF; COG3754
929102000650	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
929102000651	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
929102000652	Predicted membrane protein (DUF2142); Region: DUF2142; pfam09913
929102000653	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
929102000654	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
929102000655	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
929102000656	active site
929102000657	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
929102000658	dolichyl-phosphate beta-D-mannosyltransferase; Region: PLN02726
929102000659	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
929102000660	Ligand binding site; other site
929102000661	Putative Catalytic site; other site
929102000662	DXD motif; other site
929102000663	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
929102000664	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
929102000665	active site
929102000666	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
929102000667	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
929102000668	active site
929102000669	putative glycosyl transferase; Provisional; Region: PRK10073
929102000670	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
929102000671	LicD family; Region: LicD; pfam04991
929102000672	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
929102000673	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
929102000674	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
929102000675	Clostridial hydrophobic, with a conserved W residue, domain; Region: ChW; smart00728
929102000676	Clostridial hydrophobic W; Region: ChW; pfam07538
929102000677	Clostridial hydrophobic W; Region: ChW; pfam07538
929102000678	Clostridial hydrophobic, with a conserved W residue, domain; Region: ChW; smart00728
929102000679	Clostridial hydrophobic, with a conserved W residue, domain; Region: ChW; smart00728
929102000680	Clostridial hydrophobic W; Region: ChW; pfam07538
929102000681	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
929102000682	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
929102000683	active site
929102000684	catalytic site [active]
929102000685	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
929102000686	Cytidylyltransferase; Region: CTP_transf_2; pfam01467
929102000687	active site
929102000688	nucleotide binding site [chemical binding]; other site
929102000689	HIGH motif; other site
929102000690	KMSKS motif; other site
929102000691	Endo-N-acetylmuramidases (muramidases) are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues; Region: GH25_muramidase; cl10448
929102000692	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
929102000693	active site
929102000694	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
929102000695	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
929102000696	Clostridial hydrophobic, with a conserved W residue, domain; Region: ChW; smart00728
929102000697	Clostridial hydrophobic, with a conserved W residue, domain; Region: ChW; smart00728
929102000698	Clostridial hydrophobic W; Region: ChW; pfam07538
929102000699	Clostridial hydrophobic, with a conserved W residue, domain; Region: ChW; smart00728
929102000700	Clostridial hydrophobic W; Region: ChW; pfam07538
929102000701	Clostridial hydrophobic W; Region: ChW; pfam07538
929102000702	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
929102000703	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
929102000704	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
929102000705	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
929102000706	active site
929102000707	GTPase YqeH; Provisional; Region: PRK13796
929102000708	Circularly permuted YqeH GTPase; Region: YqeH; cd01855
929102000709	GTP/Mg2+ binding site [chemical binding]; other site
929102000710	G4 box; other site
929102000711	G5 box; other site
929102000712	G1 box; other site
929102000713	Switch I region; other site
929102000714	G2 box; other site
929102000715	G3 box; other site
929102000716	Switch II region; other site
929102000717	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_29; cd04688
929102000718	nudix motif; other site
929102000719	GTPases [General function prediction only]; Region: HflX; COG2262
929102000720	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
929102000721	HflX GTPase family; Region: HflX; cd01878
929102000722	G1 box; other site
929102000723	GTP/Mg2+ binding site [chemical binding]; other site
929102000724	Switch I region; other site
929102000725	G2 box; other site
929102000726	G3 box; other site
929102000727	Switch II region; other site
929102000728	G4 box; other site
929102000729	G5 box; other site
929102000730	Predicted RNA-binding protein containing KH domain, possibly ribosomal protein [Translation, ribosomal structure and biogenesis]; Region: COG1534
929102000731	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
929102000732	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
929102000733	active site
929102000734	(T/H)XGH motif; other site
929102000735	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
929102000736	Zn2+ binding site [ion binding]; other site
929102000737	Mg2+ binding site [ion binding]; other site
929102000738	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929102000739	Coenzyme A binding pocket [chemical binding]; other site
929102000740	Uncharacterized homolog of plant Iojap protein [Function unknown]; Region: COG0799
929102000741	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929102000742	S-adenosylmethionine binding site [chemical binding]; other site
929102000743	HIGH Nucleotidyl Transferase; Region: HIGH_NTase1; pfam05636
929102000744	hypothetical protein; Provisional; Region: PRK13670
929102000745	hypothetical protein; Provisional; Region: PRK12378
929102000746	Uncharacterized conserved protein [Function unknown]; Region: COG4832
929102000747	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
929102000748	ligand binding site [chemical binding]; other site
929102000749	active site
929102000750	UGI interface [polypeptide binding]; other site
929102000751	catalytic site [active]
929102000752	alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases; Region: MDR_like_2; cd05289
929102000753	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
929102000754	putative NAD(P) binding site [chemical binding]; other site
929102000755	mycofactocin system transcriptional regulator; Region: mycofact_TetR; TIGR03968
929102000756	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
929102000757	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929102000758	putative substrate translocation pore; other site
929102000759	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929102000760	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
929102000761	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
929102000762	DNA binding residues [nucleotide binding]
929102000763	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
929102000764	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
929102000765	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
929102000766	active site
929102000767	motif I; other site
929102000768	motif II; other site
929102000769	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
929102000770	phosphoglycerate kinase; Provisional; Region: pgk; PRK00073
929102000771	Phosphoglycerate kinase; Region: PGK; pfam00162
929102000772	substrate binding site [chemical binding]; other site
929102000773	hinge regions; other site
929102000774	ADP binding site [chemical binding]; other site
929102000775	catalytic site [active]
929102000776	DhaKLM operon coactivator DhaQ; Provisional; Region: PRK14483
929102000777	Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Region: DAK1; COG2376
929102000778	probable dihydroxyacetone kinase regulator; Region: DHAK_reg; TIGR02366
929102000779	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
929102000780	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK14481
929102000781	Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Region: DAK1; COG2376
929102000782	Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Region: DAK1; COG2376
929102000783	dihydroxyacetone kinase, phosphoprotein-dependent, L subunit; Region: dha_L_ycgS; TIGR02365
929102000784	Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism]; Region: GlpF; COG0580
929102000785	amphipathic channel; other site
929102000786	Asn-Pro-Ala signature motifs; other site
929102000787	Dipeptidase [Amino acid transport and metabolism]; Region: PepD; COG4690
929102000788	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
929102000789	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
929102000790	Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092
929102000791	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
929102000792	putative RNA binding site [nucleotide binding]; other site
929102000793	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
929102000794	Uncharacterized protein conserved in bacteria [Carbohydrate transport and metabolism]; Region: Fbp; COG3855
929102000795	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
929102000796	HI0933-like protein; Region: HI0933_like; pfam03486
929102000797	putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834
929102000798	Ribosomal protein S13/S18; Region: Ribosomal_S13; cl00331
929102000799	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
929102000800	putative substrate binding site [chemical binding]; other site
929102000801	putative ATP binding site [chemical binding]; other site
929102000802	Phage envelope protein [General function prediction only]; Region: COG5562
929102000803	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
929102000804	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
929102000805	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929102000806	Walker A/P-loop; other site
929102000807	ATP binding site [chemical binding]; other site
929102000808	Q-loop/lid; other site
929102000809	ABC transporter signature motif; other site
929102000810	Walker B; other site
929102000811	D-loop; other site
929102000812	H-loop/switch region; other site
929102000813	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
929102000814	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
929102000815	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
929102000816	Walker A/P-loop; other site
929102000817	ATP binding site [chemical binding]; other site
929102000818	Q-loop/lid; other site
929102000819	ABC transporter signature motif; other site
929102000820	Walker B; other site
929102000821	D-loop; other site
929102000822	H-loop/switch region; other site
929102000823	Uncharacterized protein/domain associated with GTPases [Function unknown]; Region: COG3597
929102000824	putative oxidoreductase; Provisional; Region: PRK10206
929102000825	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
929102000826	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
929102000827	S-ribosylhomocysteinase; Provisional; Region: PRK02260
929102000828	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
929102000829	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
929102000830	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
929102000831	active site
929102000832	catalytic tetrad [active]
929102000833	Isochorismatase family; Region: Isochorismatase; pfam00857
929102000834	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
929102000835	catalytic triad [active]
929102000836	conserved cis-peptide bond; other site
929102000837	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
929102000838	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
929102000839	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
929102000840	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
929102000841	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
929102000842	ATP cone domain; Region: ATP-cone; pfam03477
929102000843	Class III ribonucleotide reductase; Region: RNR_III; cd01675
929102000844	effector binding site; other site
929102000845	active site
929102000846	Zn binding site [ion binding]; other site
929102000847	glycine loop; other site
929102000848	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
929102000849	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
929102000850	FeS/SAM binding site; other site
929102000851	Uncharacterized protein conserved in bacteria (DUF2325); Region: DUF2325; pfam10087
929102000852	enolase; Provisional; Region: eno; PRK00077
929102000853	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
929102000854	dimer interface [polypeptide binding]; other site
929102000855	metal binding site [ion binding]; metal-binding site
929102000856	substrate binding pocket [chemical binding]; other site
929102000857	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13642
929102000858	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
929102000859	Walker A/P-loop; other site
929102000860	ATP binding site [chemical binding]; other site
929102000861	Q-loop/lid; other site
929102000862	ABC transporter signature motif; other site
929102000863	Walker B; other site
929102000864	D-loop; other site
929102000865	H-loop/switch region; other site
929102000866	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13643
929102000867	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
929102000868	Walker A/P-loop; other site
929102000869	ATP binding site [chemical binding]; other site
929102000870	Q-loop/lid; other site
929102000871	ABC transporter signature motif; other site
929102000872	Walker B; other site
929102000873	D-loop; other site
929102000874	H-loop/switch region; other site
929102000875	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
929102000876	Glyoxalase-like domain; Region: Glyoxalase_2; pfam12681
929102000877	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
929102000878	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Region: DapD_Ac; TIGR03532
929102000879	Tetrahydrodipicolinate succinyltransferase N-terminal; Region: DapH_N; pfam08503
929102000880	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
929102000881	putative trimer interface [polypeptide binding]; other site
929102000882	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
929102000883	putative CoA binding site [chemical binding]; other site
929102000884	putative trimer interface [polypeptide binding]; other site
929102000885	putative CoA binding site [chemical binding]; other site
929102000886	M20 Peptidase Aminoacyclase-1 YkuR-like proteins, including YkuR and Ama/HipO/HyuC proteins; Region: M20_Acy1_YkuR_like; cd05670
929102000887	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
929102000888	metal binding site [ion binding]; metal-binding site
929102000889	putative dimer interface [polypeptide binding]; other site
929102000890	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
929102000891	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
929102000892	Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692
929102000893	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
929102000894	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
929102000895	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
929102000896	RNA binding surface [nucleotide binding]; other site
929102000897	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
929102000898	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
929102000899	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
929102000900	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
929102000901	RNA binding site [nucleotide binding]; other site
929102000902	SprT homologues; Region: SprT; cl01182
929102000903	hypothetical protein; Provisional; Region: PRK04351
929102000904	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
929102000905	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
929102000906	active site
929102000907	purine riboside binding site [chemical binding]; other site
929102000908	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
929102000909	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
929102000910	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
929102000911	hypothetical protein; Provisional; Region: PRK13667
929102000912	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
929102000913	Glycoprotease family; Region: Peptidase_M22; pfam00814
929102000914	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
929102000915	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929102000916	Coenzyme A binding pocket [chemical binding]; other site
929102000917	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
929102000918	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929102000919	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
929102000920	Coenzyme A binding pocket [chemical binding]; other site
929102000921	UGMP family protein; Validated; Region: PRK09604
929102000922	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
929102000923	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; pfam12974
929102000924	ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: COG3638
929102000925	ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Region: ABC_PhnC_transporter; cd03256
929102000926	Walker A/P-loop; other site
929102000927	ATP binding site [chemical binding]; other site
929102000928	Q-loop/lid; other site
929102000929	ABC transporter signature motif; other site
929102000930	Walker B; other site
929102000931	D-loop; other site
929102000932	H-loop/switch region; other site
929102000933	phosphonate ABC transporter, permease protein PhnE; Region: PhnE; TIGR01097
929102000934	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
929102000935	dimer interface [polypeptide binding]; other site
929102000936	conserved gate region; other site
929102000937	putative PBP binding loops; other site
929102000938	ABC-ATPase subunit interface; other site
929102000939	ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism]; Region: COG3639
929102000940	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
929102000941	dimer interface [polypeptide binding]; other site
929102000942	conserved gate region; other site
929102000943	ABC-ATPase subunit interface; other site
929102000944	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
929102000945	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
929102000946	active site
929102000947	metal binding site [ion binding]; metal-binding site
929102000948	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
929102000949	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
929102000950	dimer interface [polypeptide binding]; other site
929102000951	catalytic triad [active]
929102000952	peroxidatic and resolving cysteines [active]
929102000953	Aminopeptidase N [Amino acid transport and metabolism]; Region: PepN; COG0308
929102000954	Peptidase M1 Aminopeptidase N family incudes tricorn interacting factor F3, Endoplasmic reticulum aminopeptidase 1 (ERAP1), Aminopeptidase Q (APQ); Region: M1_APN_2; cd09601
929102000955	Zn binding site [ion binding]; other site
929102000956	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929102000957	putative substrate translocation pore; other site
929102000958	H+ Antiporter protein; Region: 2A0121; TIGR00900
929102000959	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
929102000960	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
929102000961	Cation efflux family; Region: Cation_efflux; pfam01545
929102000962	Predicted transcriptional regulators [Transcription]; Region: COG1695
929102000963	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
929102000964	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
929102000965	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
929102000966	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929102000967	Walker A/P-loop; other site
929102000968	ATP binding site [chemical binding]; other site
929102000969	Q-loop/lid; other site
929102000970	ABC transporter signature motif; other site
929102000971	Walker B; other site
929102000972	D-loop; other site
929102000973	H-loop/switch region; other site
929102000974	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
929102000975	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
929102000976	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
929102000977	Walker A/P-loop; other site
929102000978	ATP binding site [chemical binding]; other site
929102000979	Q-loop/lid; other site
929102000980	ABC transporter signature motif; other site
929102000981	Walker B; other site
929102000982	D-loop; other site
929102000983	H-loop/switch region; other site
929102000984	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
929102000985	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
929102000986	hinge; other site
929102000987	active site
929102000988	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4443
929102000989	BioY family; Region: BioY; pfam02632
929102000990	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
929102000991	putative deacylase active site [active]
929102000992	Predicted membrane protein [Function unknown]; Region: COG3859
929102000993	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
929102000994	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
929102000995	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
929102000996	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
929102000997	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
929102000998	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
929102000999	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
929102001000	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
929102001001	ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism]; Region: AbcC; COG1135
929102001002	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
929102001003	Walker A/P-loop; other site
929102001004	ATP binding site [chemical binding]; other site
929102001005	Q-loop/lid; other site
929102001006	ABC transporter signature motif; other site
929102001007	Walker B; other site
929102001008	D-loop; other site
929102001009	H-loop/switch region; other site
929102001010	NIL domain; Region: NIL; pfam09383
929102001011	ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism]; Region: AbcD; COG2011
929102001012	hypothetical protein; Provisional; Region: PRK13661
929102001013	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
929102001014	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
929102001015	Walker A/P-loop; other site
929102001016	ATP binding site [chemical binding]; other site
929102001017	Q-loop/lid; other site
929102001018	ABC transporter signature motif; other site
929102001019	Walker B; other site
929102001020	D-loop; other site
929102001021	H-loop/switch region; other site
929102001022	ATP-binding cassette cobalt transporter; Region: DUF3744; pfam12558
929102001023	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
929102001024	Walker A/P-loop; other site
929102001025	ATP binding site [chemical binding]; other site
929102001026	Q-loop/lid; other site
929102001027	ABC transporter signature motif; other site
929102001028	Walker B; other site
929102001029	D-loop; other site
929102001030	H-loop/switch region; other site
929102001031	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
929102001032	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
929102001033	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929102001034	non-specific DNA binding site [nucleotide binding]; other site
929102001035	salt bridge; other site
929102001036	sequence-specific DNA binding site [nucleotide binding]; other site
929102001037	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
929102001038	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
929102001039	Walker A/P-loop; other site
929102001040	ATP binding site [chemical binding]; other site
929102001041	Q-loop/lid; other site
929102001042	ABC transporter signature motif; other site
929102001043	Walker B; other site
929102001044	D-loop; other site
929102001045	H-loop/switch region; other site
929102001046	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
929102001047	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
929102001048	ABC-ATPase subunit  interface; other site
929102001049	dimer interface [polypeptide binding]; other site
929102001050	putative PBP binding regions; other site
929102001051	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
929102001052	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
929102001053	ABC-ATPase subunit  interface; other site
929102001054	dimer interface [polypeptide binding]; other site
929102001055	putative PBP binding regions; other site
929102001056	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
929102001057	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
929102001058	intersubunit interface [polypeptide binding]; other site
929102001059	Transcriptional regulator [Transcription]; Region: LysR; COG0583
929102001060	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
929102001061	LysR substrate binding domain; Region: LysR_substrate; pfam03466
929102001062	dimerization interface [polypeptide binding]; other site
929102001063	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
929102001064	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929102001065	putative substrate translocation pore; other site
929102001066	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
929102001067	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
929102001068	active site
929102001069	catalytic tetrad [active]
929102001070	Predicted transcriptional regulators [Transcription]; Region: COG1733
929102001071	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
929102001072	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
929102001073	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
929102001074	putative metal binding site [ion binding]; other site
929102001075	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
929102001076	catalytic core [active]
929102001077	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
929102001078	peroxiredoxin; Region: AhpC; TIGR03137
929102001079	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
929102001080	dimer interface [polypeptide binding]; other site
929102001081	decamer (pentamer of dimers) interface [polypeptide binding]; other site
929102001082	catalytic triad [active]
929102001083	peroxidatic and resolving cysteines [active]
929102001084	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
929102001085	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
929102001086	catalytic residue [active]
929102001087	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
929102001088	catalytic residues [active]
929102001089	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
929102001090	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
929102001091	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
929102001092	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
929102001093	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
929102001094	recombination protein RecR; Reviewed; Region: recR; PRK00076
929102001095	RecR protein; Region: RecR; pfam02132
929102001096	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
929102001097	putative active site [active]
929102001098	putative metal-binding site [ion binding]; other site
929102001099	tetramer interface [polypeptide binding]; other site
929102001100	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
929102001101	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
929102001102	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
929102001103	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
929102001104	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
929102001105	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
929102001106	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
929102001107	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
929102001108	peptide binding site [polypeptide binding]; other site
929102001109	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
929102001110	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
929102001111	peptide binding site [polypeptide binding]; other site
929102001112	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
929102001113	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
929102001114	dimer interface [polypeptide binding]; other site
929102001115	conserved gate region; other site
929102001116	putative PBP binding loops; other site
929102001117	ABC-ATPase subunit interface; other site
929102001118	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
929102001119	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
929102001120	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
929102001121	dimer interface [polypeptide binding]; other site
929102001122	conserved gate region; other site
929102001123	putative PBP binding loops; other site
929102001124	ABC-ATPase subunit interface; other site
929102001125	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
929102001126	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
929102001127	Walker A/P-loop; other site
929102001128	ATP binding site [chemical binding]; other site
929102001129	Q-loop/lid; other site
929102001130	ABC transporter signature motif; other site
929102001131	Walker B; other site
929102001132	D-loop; other site
929102001133	H-loop/switch region; other site
929102001134	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
929102001135	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
929102001136	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
929102001137	Walker A/P-loop; other site
929102001138	ATP binding site [chemical binding]; other site
929102001139	Q-loop/lid; other site
929102001140	ABC transporter signature motif; other site
929102001141	Walker B; other site
929102001142	D-loop; other site
929102001143	H-loop/switch region; other site
929102001144	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
929102001145	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
929102001146	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
929102001147	G1 box; other site
929102001148	putative GEF interaction site [polypeptide binding]; other site
929102001149	GTP/Mg2+ binding site [chemical binding]; other site
929102001150	Switch I region; other site
929102001151	G2 box; other site
929102001152	G3 box; other site
929102001153	Switch II region; other site
929102001154	G4 box; other site
929102001155	G5 box; other site
929102001156	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
929102001157	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
929102001158	DEAD-like helicases superfamily; Region: DEXDc; smart00487
929102001159	ATP binding site [chemical binding]; other site
929102001160	Mg++ binding site [ion binding]; other site
929102001161	motif III; other site
929102001162	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
929102001163	nucleotide binding region [chemical binding]; other site
929102001164	ATP-binding site [chemical binding]; other site
929102001165	GTPase Era; Reviewed; Region: era; PRK00089
929102001166	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
929102001167	G1 box; other site
929102001168	GTP/Mg2+ binding site [chemical binding]; other site
929102001169	Switch I region; other site
929102001170	G2 box; other site
929102001171	Switch II region; other site
929102001172	G3 box; other site
929102001173	G4 box; other site
929102001174	G5 box; other site
929102001175	KH domain; Region: KH_2; pfam07650
929102001176	asparagine synthetase B; Provisional; Region: asnB; PRK09431
929102001177	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
929102001178	dimer interface [polypeptide binding]; other site
929102001179	active site
929102001180	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
929102001181	Ligand Binding Site [chemical binding]; other site
929102001182	Molecular Tunnel; other site
929102001183	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
929102001184	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
929102001185	DNA binding site [nucleotide binding]
929102001186	catalytic residue [active]
929102001187	H2TH interface [polypeptide binding]; other site
929102001188	putative catalytic residues [active]
929102001189	turnover-facilitating residue; other site
929102001190	intercalation triad [nucleotide binding]; other site
929102001191	8OG recognition residue [nucleotide binding]; other site
929102001192	putative reading head residues; other site
929102001193	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
929102001194	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
929102001195	recombinase A; Provisional; Region: recA; PRK09354
929102001196	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
929102001197	hexamer interface [polypeptide binding]; other site
929102001198	Walker A motif; other site
929102001199	ATP binding site [chemical binding]; other site
929102001200	Walker B motif; other site
929102001201	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
929102001202	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
929102001203	Regulatory protein involved in competence development and sporulation [Replication, recombination and repair;    Signal transduction mechanisms]; Region: COG3679
929102001204	Uncharacterized protein conserved in bacteria (DUF2129); Region: DUF2129; cl11453
929102001205	Uncharacterized subgroup 1 of the CYTH-like superfamily; Region: CYTH-like_Pase_1; cd07762
929102001206	putative active site [active]
929102001207	putative metal binding residues [ion binding]; other site
929102001208	signature motif; other site
929102001209	putative triphosphate binding site [ion binding]; other site
929102001210	Protein of unknown function (DUF817); Region: DUF817; cl01520
929102001211	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
929102001212	synthetase active site [active]
929102001213	NTP binding site [chemical binding]; other site
929102001214	metal binding site [ion binding]; metal-binding site
929102001215	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK04885
929102001216	ATP-NAD kinase; Region: NAD_kinase; pfam01513
929102001217	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
929102001218	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
929102001219	active site
929102001220	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
929102001221	active site
929102001222	lysine transporter; Provisional; Region: PRK10836
929102001223	Predicted flavoprotein [General function prediction only]; Region: COG0431
929102001224	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
929102001225	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
929102001226	ApbE family; Region: ApbE; pfam02424
929102001227	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
929102001228	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
929102001229	dimer interface [polypeptide binding]; other site
929102001230	putative anticodon binding site; other site
929102001231	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
929102001232	motif 1; other site
929102001233	active site
929102001234	motif 2; other site
929102001235	motif 3; other site
929102001236	Transcriptional regulator [Transcription]; Region: LysR; COG0583
929102001237	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
929102001238	LysR substrate binding domain; Region: LysR_substrate; pfam03466
929102001239	dimerization interface [polypeptide binding]; other site
929102001240	Conserved hypothetical protein 698; Region: Cons_hypoth698; pfam03601
929102001241	L-lactate dehydrogenase; Reviewed; Region: ldh; PRK00066
929102001242	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
929102001243	tetramer (dimer of dimers) interface [polypeptide binding]; other site
929102001244	NAD binding site [chemical binding]; other site
929102001245	dimer interface [polypeptide binding]; other site
929102001246	substrate binding site [chemical binding]; other site
929102001247	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
929102001248	C4-dicarboxylate transporters of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family; Region: TDT_C4-dicarb_trans; cd09325
929102001249	gating phenylalanine in ion channel; other site
929102001250	thiamine biosynthesis protein ThiI; Provisional; Region: PRK01565
929102001251	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
929102001252	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
929102001253	Ligand Binding Site [chemical binding]; other site
929102001254	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
929102001255	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929102001256	putative substrate translocation pore; other site
929102001257	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929102001258	Acyl carrier protein phosphodiesterase [Lipid metabolism]; Region: AcpD; COG1182
929102001259	peroxiredoxin, SACOL1771 subfamily; Region: perox_SACOL1771; TIGR03563
929102001260	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
929102001261	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
929102001262	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
929102001263	active site
929102001264	HIGH motif; other site
929102001265	dimer interface [polypeptide binding]; other site
929102001266	KMSKS motif; other site
929102001267	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
929102001268	RNA binding surface [nucleotide binding]; other site
929102001269	Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]; Region: MrcB; COG0744
929102001270	Transglycosylase; Region: Transgly; pfam00912
929102001271	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
929102001272	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
929102001273	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
929102001274	oligomer interface [polypeptide binding]; other site
929102001275	active site
929102001276	metal binding site [ion binding]; metal-binding site
929102001277	Predicted small secreted protein [Function unknown]; Region: COG5584
929102001278	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
929102001279	catalytic residues [active]
929102001280	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
929102001281	putative tRNA-binding site [nucleotide binding]; other site
929102001282	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
929102001283	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
929102001284	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
929102001285	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
929102001286	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
929102001287	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
929102001288	dimer interface [polypeptide binding]; other site
929102001289	ssDNA binding site [nucleotide binding]; other site
929102001290	tetramer (dimer of dimers) interface [polypeptide binding]; other site
929102001291	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
929102001292	oligomerisation interface [polypeptide binding]; other site
929102001293	mobile loop; other site
929102001294	roof hairpin; other site
929102001295	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
929102001296	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
929102001297	ring oligomerisation interface [polypeptide binding]; other site
929102001298	ATP/Mg binding site [chemical binding]; other site
929102001299	stacking interactions; other site
929102001300	hinge regions; other site
929102001301	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
929102001302	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
929102001303	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: VicK; COG5002
929102001304	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
929102001305	putative active site [active]
929102001306	heme pocket [chemical binding]; other site
929102001307	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
929102001308	dimer interface [polypeptide binding]; other site
929102001309	phosphorylation site [posttranslational modification]
929102001310	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929102001311	ATP binding site [chemical binding]; other site
929102001312	Mg2+ binding site [ion binding]; other site
929102001313	G-X-G motif; other site
929102001314	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
929102001315	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929102001316	active site
929102001317	phosphorylation site [posttranslational modification]
929102001318	intermolecular recognition site; other site
929102001319	dimerization interface [polypeptide binding]; other site
929102001320	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
929102001321	DNA binding site [nucleotide binding]
929102001322	thymidylate kinase; Validated; Region: tmk; PRK00698
929102001323	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
929102001324	TMP-binding site; other site
929102001325	ATP-binding site [chemical binding]; other site
929102001326	DNA polymerase III subunit delta'; Validated; Region: PRK07276
929102001327	DNA polymerase III subunit delta'; Validated; Region: PRK08485
929102001328	Uncharacterized homolog of PSP1 [Function unknown]; Region: COG1774
929102001329	Regulator of replication initiation timing [Replication,    recombination, and repair]; Region: COG4467
929102001330	Predicted methyltransferases [General function prediction only]; Region: COG0313
929102001331	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
929102001332	putative SAM binding site [chemical binding]; other site
929102001333	putative homodimer interface [polypeptide binding]; other site
929102001334	mevalonate kinase; Region: mevalon_kin; TIGR00549
929102001335	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
929102001336	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
929102001337	Mevalonate pyrophosphate decarboxylase [Lipid metabolism]; Region: MVD1; COG3407
929102001338	diphosphomevalonate decarboxylase; Region: PLN02407
929102001339	Mevalonate kinase [Lipid metabolism]; Region: ERG12; COG1577
929102001340	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
929102001341	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
929102001342	isopentenyl pyrophosphate isomerase; Provisional; Region: PRK05437
929102001343	Isopentenyl-diphosphate:dimethylallyl diphosphate isomerase type 2 (IDI-2) FMN-binding domain. Two types of IDIs have been characterized at present. The long known IDI-1 is only dependent on divalent metals for activity, whereas IDI-2 requires a metal; Region: IDI-2_FMN; cd02811
929102001344	homotetramer interface [polypeptide binding]; other site
929102001345	FMN binding site [chemical binding]; other site
929102001346	homodimer contacts [polypeptide binding]; other site
929102001347	putative active site [active]
929102001348	putative substrate binding site [chemical binding]; other site
929102001349	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
929102001350	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
929102001351	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
929102001352	carbon starvation protein A; Provisional; Region: PRK15015
929102001353	Carbon starvation protein CstA; Region: CstA; pfam02554
929102001354	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
929102001355	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
929102001356	DEAD-like helicases superfamily; Region: DEXDc; smart00487
929102001357	ATP binding site [chemical binding]; other site
929102001358	Mg++ binding site [ion binding]; other site
929102001359	motif III; other site
929102001360	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
929102001361	nucleotide binding region [chemical binding]; other site
929102001362	ATP-binding site [chemical binding]; other site
929102001363	Uncharacterized conserved protein [Function unknown]; Region: COG1434
929102001364	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
929102001365	putative active site [active]
929102001366	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
929102001367	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
929102001368	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
929102001369	putative active site [active]
929102001370	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
929102001371	active site
929102001372	P-loop; other site
929102001373	phosphorylation site [posttranslational modification]
929102001374	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
929102001375	active site
929102001376	methionine cluster; other site
929102001377	phosphorylation site [posttranslational modification]
929102001378	metal binding site [ion binding]; metal-binding site
929102001379	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
929102001380	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
929102001381	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
929102001382	putative active site [active]
929102001383	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
929102001384	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
929102001385	6-phospho-beta-glucosidase; Reviewed; Region: celA; PRK09589
929102001386	beta-galactosidase; Region: BGL; TIGR03356
929102001387	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
929102001388	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
929102001389	nucleotide binding pocket [chemical binding]; other site
929102001390	K-X-D-G motif; other site
929102001391	catalytic site [active]
929102001392	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
929102001393	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
929102001394	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
929102001395	Dimer interface [polypeptide binding]; other site
929102001396	BRCT sequence motif; other site
929102001397	putative lipid kinase; Reviewed; Region: PRK13055
929102001398	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
929102001399	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
929102001400	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
929102001401	Walker A/P-loop; other site
929102001402	ATP binding site [chemical binding]; other site
929102001403	Q-loop/lid; other site
929102001404	ABC transporter signature motif; other site
929102001405	Walker B; other site
929102001406	D-loop; other site
929102001407	H-loop/switch region; other site
929102001408	TOBE domain; Region: TOBE_2; pfam08402
929102001409	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
929102001410	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
929102001411	dimer interface [polypeptide binding]; other site
929102001412	PYR/PP interface [polypeptide binding]; other site
929102001413	TPP binding site [chemical binding]; other site
929102001414	substrate binding site [chemical binding]; other site
929102001415	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
929102001416	Domain of unknown function; Region: EKR; smart00890
929102001417	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
929102001418	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
929102001419	TPP-binding site [chemical binding]; other site
929102001420	dimer interface [polypeptide binding]; other site
929102001421	Uncharacterized conserved protein [Function unknown]; Region: COG1624
929102001422	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
929102001423	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4856
929102001424	YbbR-like protein; Region: YbbR; pfam07949
929102001425	YbbR-like protein; Region: YbbR; pfam07949
929102001426	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14316
929102001427	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
929102001428	active site
929102001429	substrate binding site [chemical binding]; other site
929102001430	metal binding site [ion binding]; metal-binding site
929102001431	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
929102001432	DNA-binding site [nucleotide binding]; DNA binding site
929102001433	trehalose operon repressor, B. subtilis-type; Region: trehalos_R_Bsub; TIGR02404
929102001434	UTRA domain; Region: UTRA; pfam07702
929102001435	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
929102001436	HPr interaction site; other site
929102001437	glycerol kinase (GK) interaction site [polypeptide binding]; other site
929102001438	active site
929102001439	phosphorylation site [posttranslational modification]
929102001440	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
929102001441	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
929102001442	active site turn [active]
929102001443	phosphorylation site [posttranslational modification]
929102001444	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
929102001445	Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism]; Region: ATH1; COG1554
929102001446	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
929102001447	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
929102001448	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
929102001449	beta-phosphoglucomutase; Region: bPGM; TIGR01990
929102001450	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
929102001451	motif II; other site
929102001452	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
929102001453	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
929102001454	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
929102001455	nucleophilic elbow; other site
929102001456	catalytic triad; other site
929102001457	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
929102001458	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
929102001459	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929102001460	Coenzyme A binding pocket [chemical binding]; other site
929102001461	Transcriptional regulator [Transcription]; Region: LytR; COG1316
929102001462	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
929102001463	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
929102001464	dimerization interface 3.5A [polypeptide binding]; other site
929102001465	active site
929102001466	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
929102001467	dimer interface [polypeptide binding]; other site
929102001468	substrate binding site [chemical binding]; other site
929102001469	ATP binding site [chemical binding]; other site
929102001470	Predicted membrane protein [Function unknown]; Region: COG4720
929102001471	hypothetical protein; Provisional; Region: PRK13690
929102001472	Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075
929102001473	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
929102001474	catalytic residue [active]
929102001475	CTP synthetase; Validated; Region: pyrG; PRK05380
929102001476	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
929102001477	Catalytic site [active]
929102001478	active site
929102001479	UTP binding site [chemical binding]; other site
929102001480	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
929102001481	active site
929102001482	putative oxyanion hole; other site
929102001483	catalytic triad [active]
929102001484	Predicted membrane protein [Function unknown]; Region: COG4420
929102001485	Protein of unknown function (DUF2929); Region: DUF2929; pfam11151
929102001486	Nucleoside 2-deoxyribosyltransferase [Nucleotide transport and metabolism]; Region: COG3613
929102001487	Possible lysine decarboxylase; Region: Lysine_decarbox; pfam03641
929102001488	Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428
929102001489	Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1; Region: dNK; cd01673
929102001490	Substrate-binding site [chemical binding]; other site
929102001491	Substrate specificity [chemical binding]; other site
929102001492	DNA polymerase III DnaE; Reviewed; Region: dnaE; PRK07279
929102001493	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III; Region: PHP_PolIIIA; cd07431
929102001494	active site
929102001495	PHP Thumb interface [polypeptide binding]; other site
929102001496	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
929102001497	generic binding surface II; other site
929102001498	generic binding surface I; other site
929102001499	Predicted membrane protein, hemolysin III homolog [General function prediction only]; Region: COG1272
929102001500	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
929102001501	EDD domain protein, DegV family; Region: DegV; TIGR00762
929102001502	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
929102001503	Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_YpmR_like; cd04506
929102001504	active site
929102001505	catalytic triad [active]
929102001506	oxyanion hole [active]
929102001507	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
929102001508	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
929102001509	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4698
929102001510	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
929102001511	IHF dimer interface [polypeptide binding]; other site
929102001512	IHF - DNA interface [nucleotide binding]; other site
929102001513	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
929102001514	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929102001515	Coenzyme A binding pocket [chemical binding]; other site
929102001516	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
929102001517	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
929102001518	DNA binding site [nucleotide binding]
929102001519	active site
929102001520	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Ada; COG2169
929102001521	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
929102001522	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929102001523	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929102001524	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
929102001525	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
929102001526	Walker A/P-loop; other site
929102001527	ATP binding site [chemical binding]; other site
929102001528	Q-loop/lid; other site
929102001529	ABC transporter signature motif; other site
929102001530	Walker B; other site
929102001531	D-loop; other site
929102001532	H-loop/switch region; other site
929102001533	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
929102001534	LytTr DNA-binding domain; Region: LytTR; pfam04397
929102001535	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
929102001536	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
929102001537	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
929102001538	catalytic residue [active]
929102001539	FOG: Glucan-binding domain (YG repeat) [General function prediction only]; Region: COG5263
929102001540	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
929102001541	NlpC/P60 family; Region: NLPC_P60; cl17555
929102001542	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
929102001543	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
929102001544	peptide binding site [polypeptide binding]; other site
929102001545	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
929102001546	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
929102001547	dimer interface [polypeptide binding]; other site
929102001548	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929102001549	catalytic residue [active]
929102001550	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
929102001551	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
929102001552	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
929102001553	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
929102001554	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
929102001555	Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]; Region: MrcB; COG0744
929102001556	Transglycosylase; Region: Transgly; pfam00912
929102001557	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
929102001558	Holliday junction-specific endonuclease; Reviewed; Region: recU; PRK02234
929102001559	hypothetical protein; Provisional; Region: PRK13660
929102001560	Arsenate Reductase (ArsC) family, Spx subfamily; Spx is a unique RNA polymerase (RNAP)-binding protein present in bacilli and some mollicutes. It inhibits transcription by binding to the C-terminal domain of the alpha subunit of RNAP, disrupting complex...; Region: ArsC_Spx; cd03032
929102001561	ArsC family; Region: ArsC; pfam03960
929102001562	putative catalytic residues [active]
929102001563	thiol/disulfide switch; other site
929102001564	hypothetical protein; Provisional; Region: PRK04387
929102001565	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
929102001566	Inositol-monophosphatase-like domains. This family of phosphatases is dependent on bivalent metal ions such as Mg++, and many members are inhibited by Li+ (which is thought to displace a bivalent ion in the active site). Substrates include fructose-1; Region: IMPase_like; cd01637
929102001567	active site
929102001568	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
929102001569	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
929102001570	hinge; other site
929102001571	active site
929102001572	trigger factor; Provisional; Region: tig; PRK01490
929102001573	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
929102001574	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
929102001575	DNA primase, catalytic core; Region: dnaG; TIGR01391
929102001576	CHC2 zinc finger; Region: zf-CHC2; pfam01807
929102001577	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
929102001578	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
929102001579	active site
929102001580	metal binding site [ion binding]; metal-binding site
929102001581	interdomain interaction site; other site
929102001582	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
929102001583	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
929102001584	RNA polymerase sigma factor RpoD; Validated; Region: PRK09210
929102001585	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
929102001586	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929102001587	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
929102001588	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929102001589	DNA binding residues [nucleotide binding]
929102001590	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
929102001591	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
929102001592	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
929102001593	putative active site [active]
929102001594	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
929102001595	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929102001596	putative substrate translocation pore; other site
929102001597	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929102001598	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929102001599	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
929102001600	Walker A motif; other site
929102001601	ATP binding site [chemical binding]; other site
929102001602	Walker B motif; other site
929102001603	arginine finger; other site
929102001604	UvrB/uvrC motif; Region: UVR; pfam02151
929102001605	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929102001606	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
929102001607	Walker A motif; other site
929102001608	ATP binding site [chemical binding]; other site
929102001609	Walker B motif; other site
929102001610	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
929102001611	Predicted transcriptional regulator [Transcription]; Region: COG1959
929102001612	Transcriptional regulator; Region: Rrf2; pfam02082
929102001613	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
929102001614	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
929102001615	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
929102001616	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
929102001617	active site
929102001618	catalytic residues [active]
929102001619	metal binding site [ion binding]; metal-binding site
929102001620	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
929102001621	putative active site [active]
929102001622	Ap4A binding site [chemical binding]; other site
929102001623	nudix motif; other site
929102001624	putative metal binding site [ion binding]; other site
929102001625	excinuclease ABC subunit B; Provisional; Region: PRK05298
929102001626	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
929102001627	ATP binding site [chemical binding]; other site
929102001628	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
929102001629	nucleotide binding region [chemical binding]; other site
929102001630	ATP-binding site [chemical binding]; other site
929102001631	Ultra-violet resistance protein B; Region: UvrB; pfam12344
929102001632	UvrB/uvrC motif; Region: UVR; pfam02151
929102001633	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
929102001634	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
929102001635	substrate binding pocket [chemical binding]; other site
929102001636	membrane-bound complex binding site; other site
929102001637	hinge residues; other site
929102001638	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Amino acid transport and metabolism]; Region: ArgE; COG0624
929102001639	Peptidase M20 acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase (ArgE/DapE)-like; Region: M20_ArgE_DapE_like; cd08659
929102001640	metal binding site [ion binding]; metal-binding site
929102001641	dimer interface [polypeptide binding]; other site
929102001642	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK06079
929102001643	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
929102001644	NAD binding site [chemical binding]; other site
929102001645	homotetramer interface [polypeptide binding]; other site
929102001646	homodimer interface [polypeptide binding]; other site
929102001647	substrate binding site [chemical binding]; other site
929102001648	active site
929102001649	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
929102001650	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929102001651	Walker A/P-loop; other site
929102001652	ATP binding site [chemical binding]; other site
929102001653	Q-loop/lid; other site
929102001654	ABC transporter signature motif; other site
929102001655	Walker B; other site
929102001656	D-loop; other site
929102001657	H-loop/switch region; other site
929102001658	OxaA-like protein precursor; Provisional; Region: PRK02463
929102001659	60Kd inner membrane protein; Region: 60KD_IMP; cl00489
929102001660	Eukaryotic phosphomannomutase; Region: PMM; cl17107
929102001661	HAD-superfamily hydrolase, subfamily IIB; Region: HAD-SF-IIB; TIGR01484
929102001662	Predicted membrane protein [Function unknown]; Region: COG4684
929102001663	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
929102001664	phosphopantothenoylcysteine decarboxylase, streptococcal; Region: coaC_strep; TIGR02113
929102001665	Flavoprotein; Region: Flavoprotein; pfam02441
929102001666	phosphopantothenate--cysteine ligase; Validated; Region: PRK06732
929102001667	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235
929102001668	active site 1 [active]
929102001669	dimer interface [polypeptide binding]; other site
929102001670	hexamer interface [polypeptide binding]; other site
929102001671	active site 2 [active]
929102001672	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; cl02930
929102001673	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
929102001674	ATPase, P-type (transporting), HAD superfamily, subfamily IC; Region: ATPase_P-type; TIGR01494
929102001675	Soluble P-type ATPase [General function prediction only]; Region: COG4087
929102001676	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
929102001677	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929102001678	Coenzyme A binding pocket [chemical binding]; other site
929102001679	Uncharacterized conserved protein [Function unknown]; Region: COG1434
929102001680	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
929102001681	putative active site [active]
929102001682	Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) [Signal transduction mechanisms]; Region: COG3476
929102001683	Predicted membrane protein [Function unknown]; Region: COG4852
929102001684	Predicted kinase related to dihydroxyacetone kinase [General function prediction only]; Region: COG1461
929102001685	DAK2 domain; Region: Dak2; pfam02734
929102001686	Dihydroxyacetone kinase family; Region: Dak1_2; pfam13684
929102001687	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
929102001688	Steroid 5-alpha reductase family enzyme [General function prediction only]; Region: COG3752
929102001689	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5294
929102001690	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
929102001691	active site
929102001692	Uncharacterized conserved protein [Function unknown]; Region: COG1359
929102001693	Uncharacterized conserved protein [Function unknown]; Region: COG2013
929102001694	DNA polymerase IV; Reviewed; Region: PRK03103
929102001695	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
929102001696	active site
929102001697	DNA binding site [nucleotide binding]
929102001698	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929102001699	Coenzyme A binding pocket [chemical binding]; other site
929102001700	hypothetical protein; Provisional; Region: PRK11281
929102001701	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
929102001702	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
929102001703	peroxiredoxin, Ohr subfamily; Region: organ_hyd_perox; TIGR03561
929102001704	thymidine kinase; Provisional; Region: PRK04296
929102001705	peptide chain release factor 1; Validated; Region: prfA; PRK00591
929102001706	This domain is found in peptide chain release factors; Region: PCRF; smart00937
929102001707	RF-1 domain; Region: RF-1; pfam00472
929102001708	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
929102001709	dimer interface [polypeptide binding]; other site
929102001710	FMN binding site [chemical binding]; other site
929102001711	NADPH bind site [chemical binding]; other site
929102001712	protein-(glutamine-N5) methyltransferase, release factor-specific; Region: RF_mod_PrmC; TIGR03534
929102001713	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929102001714	S-adenosylmethionine binding site [chemical binding]; other site
929102001715	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
929102001716	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
929102001717	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
929102001718	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
929102001719	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
929102001720	dimer interface [polypeptide binding]; other site
929102001721	active site
929102001722	glycine-pyridoxal phosphate binding site [chemical binding]; other site
929102001723	folate binding site [chemical binding]; other site
929102001724	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
929102001725	Lysozyme-like; Region: Lysozyme_like; pfam13702
929102001726	3-phosphoserine/phosphohydroxythreonine aminotransferase; Provisional; Region: PRK05355
929102001727	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
929102001728	catalytic residue [active]
929102001729	Putative D-3-Phosphoglycerate Dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_like_3; cd12174
929102001730	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
929102001731	putative ligand binding site [chemical binding]; other site
929102001732	putative NAD binding site [chemical binding]; other site
929102001733	putative catalytic site [active]
929102001734	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
929102001735	L-serine binding site [chemical binding]; other site
929102001736	ACT domain interface; other site
929102001737	phosphoserine phosphatase SerB; Region: serB; TIGR00338
929102001738	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
929102001739	motif II; other site
929102001740	acylphosphatase; Provisional; Region: PRK14434
929102001741	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
929102001742	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
929102001743	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
929102001744	flavodoxin; Validated; Region: PRK07308
929102001745	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929102001746	Major Facilitator Superfamily; Region: MFS_1; pfam07690
929102001747	putative substrate translocation pore; other site
929102001748	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
929102001749	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
929102001750	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
929102001751	active site
929102001752	Ribonuclease BN family enzyme [Replication, recombination, and repair]; Region: Rbn; COG1295
929102001753	Predicted membrane protein [Function unknown]; Region: COG2246
929102001754	GtrA-like protein; Region: GtrA; pfam04138
929102001755	Tim44-like domain; Region: Tim44; cl09208
929102001756	Predicted membrane protein [Function unknown]; Region: COG3326
929102001757	Protein of unknown function (DUF3272); Region: DUF3272; pfam11676
929102001758	HPr kinase/phosphorylase; Provisional; Region: PRK05428
929102001759	HPr Serine kinase N terminus; Region: Hpr_kinase_N; pfam02603
929102001760	HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent...; Region: HprK_C; cd01918
929102001761	Hpr binding site; other site
929102001762	active site
929102001763	homohexamer subunit interaction site [polypeptide binding]; other site
929102001764	Prolipoprotein diacylglyceryl transferase; Region: LGT; pfam01790
929102001765	Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain [General function prediction only]; Region: COG4768
929102001766	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
929102001767	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
929102001768	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
929102001769	K+ transporter [Inorganic ion transport and metabolism]; Region: Kup; COG3158
929102001770	K+ transporter [Inorganic ion transport and metabolism]; Region: Kup; COG3158
929102001771	Protein of unknown function (DUF3042); Region: DUF3042; pfam11240
929102001772	Uncharacterized conserved protein [Function unknown]; Region: COG1284
929102001773	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
929102001774	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
929102001775	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK05270
929102001776	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
929102001777	A subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual...; Region: Band_7_4; cd03407
929102001778	Sugar efflux transporter for intercellular exchange; Region: MtN3_slv; pfam03083
929102001779	ribonuclease Z; Region: RNase_Z; TIGR02651
929102001780	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
929102001781	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
929102001782	NAD(P) binding site [chemical binding]; other site
929102001783	active site
929102001784	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
929102001785	DHH family; Region: DHH; pfam01368
929102001786	DHHA1 domain; Region: DHHA1; pfam02272
929102001787	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4199
929102001788	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
929102001789	active site
929102001790	DNA-directed RNA polymerase delta subunit; Region: RNA_pol_delta; pfam05066
929102001791	Aminodeoxychorismate lyase [Coenzyme transport and metabolism]; Region: COG1559
929102001792	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
929102001793	dimerization interface [polypeptide binding]; other site
929102001794	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
929102001795	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
929102001796	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
929102001797	putative transposase OrfB; Reviewed; Region: PHA02517
929102001798	HTH-like domain; Region: HTH_21; pfam13276
929102001799	Integrase core domain; Region: rve; pfam00665
929102001800	Integrase core domain; Region: rve_3; pfam13683
929102001801	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
929102001802	Transposase; Region: HTH_Tnp_1; pfam01527
929102001803	putative transposase OrfB; Reviewed; Region: PHA02517
929102001804	HTH-like domain; Region: HTH_21; pfam13276
929102001805	Integrase core domain; Region: rve; pfam00665
929102001806	Integrase core domain; Region: rve_2; pfam13333
929102001807	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
929102001808	Homeodomain-like domain; Region: HTH_23; cl17451
929102001809	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
929102001810	Homeodomain-like domain; Region: HTH_23; cl17451
929102001811	Transcriptional repressor of class III stress genes [Transcription]; Region: CtsR; COG4463
929102001812	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
929102001813	Clp amino terminal domain; Region: Clp_N; pfam02861
929102001814	Clp amino terminal domain; Region: Clp_N; pfam02861
929102001815	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929102001816	Walker A motif; other site
929102001817	ATP binding site [chemical binding]; other site
929102001818	Walker B motif; other site
929102001819	arginine finger; other site
929102001820	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929102001821	Walker A motif; other site
929102001822	ATP binding site [chemical binding]; other site
929102001823	Walker B motif; other site
929102001824	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
929102001825	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
929102001826	30S subunit binding site; other site
929102001827	enolase; Provisional; Region: eno; PRK00077
929102001828	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
929102001829	dimer interface [polypeptide binding]; other site
929102001830	metal binding site [ion binding]; metal-binding site
929102001831	substrate binding pocket [chemical binding]; other site
929102001832	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
929102001833	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
929102001834	Walker A/P-loop; other site
929102001835	ATP binding site [chemical binding]; other site
929102001836	Q-loop/lid; other site
929102001837	ABC transporter signature motif; other site
929102001838	Walker B; other site
929102001839	D-loop; other site
929102001840	H-loop/switch region; other site
929102001841	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
929102001842	FtsX-like permease family; Region: FtsX; pfam02687
929102001843	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
929102001844	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
929102001845	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
929102001846	Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Region: Acs; COG0365
929102001847	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
929102001848	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
929102001849	acyl-activating enzyme (AAE) consensus motif; other site
929102001850	acyl-activating enzyme (AAE) consensus motif; other site
929102001851	AMP binding site [chemical binding]; other site
929102001852	active site
929102001853	CoA binding site [chemical binding]; other site
929102001854	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
929102001855	uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u2; cd12827
929102001856	Cl binding site [ion binding]; other site
929102001857	oligomer interface [polypeptide binding]; other site
929102001858	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
929102001859	Pyruvate formate lyase 1; Region: PFL1; cd01678
929102001860	coenzyme A binding site [chemical binding]; other site
929102001861	active site
929102001862	catalytic residues [active]
929102001863	glycine loop; other site
929102001864	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
929102001865	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
929102001866	CoA-binding site [chemical binding]; other site
929102001867	ATP-binding [chemical binding]; other site
929102001868	drug efflux system protein MdtG; Provisional; Region: PRK09874
929102001869	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929102001870	putative substrate translocation pore; other site
929102001871	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
929102001872	Bacterial cell division membrane protein [Cell division and chromosome partitioning]; Region: FtsW; COG0772
929102001873	Pyruvate carboxylase [Energy production and conversion]; Region: PycA; COG1038
929102001874	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
929102001875	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
929102001876	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
929102001877	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
929102001878	active site
929102001879	catalytic residues [active]
929102001880	metal binding site [ion binding]; metal-binding site
929102001881	homodimer binding site [polypeptide binding]; other site
929102001882	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
929102001883	carboxyltransferase (CT) interaction site; other site
929102001884	biotinylation site [posttranslational modification]; other site
929102001885	Citrate synthase (CS) catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the oxidative citric acid cycle (TCA or Krebs cycle). Peroxisomal CS is involved in the glyoxylate...; Region: citrate_synt_like_1_2; cd06113
929102001886	dimer interface [polypeptide binding]; other site
929102001887	Citrate synthase; Region: Citrate_synt; pfam00285
929102001888	active site
929102001889	citrylCoA binding site [chemical binding]; other site
929102001890	oxalacetate/citrate binding site [chemical binding]; other site
929102001891	coenzyme A binding site [chemical binding]; other site
929102001892	catalytic triad [active]
929102001893	aconitate hydratase; Validated; Region: PRK09277
929102001894	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
929102001895	substrate binding site [chemical binding]; other site
929102001896	ligand binding site [chemical binding]; other site
929102001897	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
929102001898	substrate binding site [chemical binding]; other site
929102001899	Isocitrate dehydrogenases [Energy production and conversion]; Region: Icd; COG0538
929102001900	isocitrate dehydrogenase; Validated; Region: PRK07362
929102001901	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
929102001902	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
929102001903	oligomer interface [polypeptide binding]; other site
929102001904	active site residues [active]
929102001905	Arsenate Reductase (ArsC) family, Spx subfamily; Spx is a unique RNA polymerase (RNAP)-binding protein present in bacilli and some mollicutes. It inhibits transcription by binding to the C-terminal domain of the alpha subunit of RNAP, disrupting complex...; Region: ArsC_Spx; cd03032
929102001906	ArsC family; Region: ArsC; pfam03960
929102001907	putative catalytic residues [active]
929102001908	thiol/disulfide switch; other site
929102001909	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
929102001910	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
929102001911	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
929102001912	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
929102001913	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
929102001914	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
929102001915	motif II; other site
929102001916	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
929102001917	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
929102001918	Acyltransferase family; Region: Acyl_transf_3; pfam01757
929102001919	N-glycosyltransferase; Provisional; Region: PRK11204
929102001920	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
929102001921	DXD motif; other site
929102001922	Cellulose synthase-like protein; Region: PLN02893
929102001923	Putative catalytic polysaccharide deacetylase domain of bacterial intercellular adhesion protein IcaB and similar proteins; Region: CE4_IcaB_5s; cd10965
929102001924	putative active site [active]
929102001925	putative metal binding site [ion binding]; other site
929102001926	Predicted outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG4932
929102001927	Collagen binding domain; Region: Collagen_bind; pfam05737
929102001928	Repeat unit of collagen-binding protein domain B; Region: CollagenBindB; cd00222
929102001929	domain interaction interfaces [polypeptide binding]; other site
929102001930	Branched-chain amino acid transport protein; Region: Branch_AA_trans; pfam05525
929102001931	Predicted acetyltransferase [General function prediction only]; Region: COG2388
929102001932	Uncharacterized conserved protein [Function unknown]; Region: COG3592
929102001933	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
929102001934	Transposase; Region: HTH_Tnp_1; pfam01527
929102001935	putative transposase OrfB; Reviewed; Region: PHA02517
929102001936	HTH-like domain; Region: HTH_21; pfam13276
929102001937	Integrase core domain; Region: rve; pfam00665
929102001938	Integrase core domain; Region: rve_3; pfam13683
929102001939	lantibiotic, gallidermin/nisin family; Region: lantibio_gallid; TIGR03731
929102001940	Lantibiotic dehydratase, N terminus; Region: Lant_dehyd_N; pfam04737
929102001941	Lantibiotic dehydratase, C terminus; Region: Lant_dehyd_C; pfam04738
929102001942	SpaB C-terminal domain; Region: SpaB_C; pfam14028
929102001943	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
929102001944	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
929102001945	Walker A/P-loop; other site
929102001946	ATP binding site [chemical binding]; other site
929102001947	Q-loop/lid; other site
929102001948	ABC transporter signature motif; other site
929102001949	Walker B; other site
929102001950	D-loop; other site
929102001951	H-loop/switch region; other site
929102001952	Lanthionine synthetase C-like protein; Region: LANC_like; pfam05147
929102001953	LanC is the cyclase enzyme of the lanthionine synthetase. Lanthinoine is a lantibiotic, a unique class of peptide antibiotics. They are ribosomally synthesized as precursor peptides and then post-translationally modified to contain thioether cross-links...; Region: LanC; cd04793
929102001954	active site
929102001955	zinc binding site [ion binding]; other site
929102001956	Peptidase S8 family domain in Lantiobiotic (lanthionine-containing antibiotics) specific proteases; Region: Peptidases_S8_Lantibiotic_specific_protease; cd07482
929102001957	active site
929102001958	catalytic triad [active]
929102001959	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
929102001960	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929102001961	active site
929102001962	phosphorylation site [posttranslational modification]
929102001963	intermolecular recognition site; other site
929102001964	dimerization interface [polypeptide binding]; other site
929102001965	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
929102001966	DNA binding site [nucleotide binding]
929102001967	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
929102001968	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
929102001969	dimer interface [polypeptide binding]; other site
929102001970	phosphorylation site [posttranslational modification]
929102001971	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929102001972	ATP binding site [chemical binding]; other site
929102001973	Mg2+ binding site [ion binding]; other site
929102001974	G-X-G motif; other site
929102001975	ATP-binding cassette domain of the bacitracin-resistance transporter; Region: ABC_BcrA_bacitracin_resist; cd03268
929102001976	gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Region: galliderm_ABC; TIGR03740
929102001977	Walker A/P-loop; other site
929102001978	ATP binding site [chemical binding]; other site
929102001979	Q-loop/lid; other site
929102001980	ABC transporter signature motif; other site
929102001981	Walker B; other site
929102001982	D-loop; other site
929102001983	H-loop/switch region; other site
929102001984	lantibiotic protection ABC transporter permease subunit, MutE/EpiE family; Region: lanti_perm_MutE; TIGR03732
929102001985	lantibiotic protection ABC transporter permease subunit, MutG family; Region: lanti_perm_MutG; TIGR03733
929102001986	Integrase core domain; Region: rve; pfam00665
929102001987	Integrase core domain; Region: rve_3; pfam13683
929102001988	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
929102001989	Transposase; Region: HTH_Tnp_1; pfam01527
929102001990	Transcriptional regulators [Transcription]; Region: PurR; COG1609
929102001991	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
929102001992	DNA binding site [nucleotide binding]
929102001993	domain linker motif; other site
929102001994	Ligand binding domain of the lacI-like transcription regulator from a novel metal-reducing bacterium Alkaliphilus Metalliredigens (strain Qymf) and its close homologs; Region: PBP1_Qymf_like; cd06291
929102001995	dimerization interface [polypeptide binding]; other site
929102001996	ligand binding site [chemical binding]; other site
929102001997	sodium binding site [ion binding]; other site
929102001998	sucrose-6-phosphate hydrolase; Region: scrB_fam; TIGR01322
929102001999	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
929102002000	substrate binding [chemical binding]; other site
929102002001	active site
929102002002	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
929102002003	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
929102002004	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
929102002005	active site turn [active]
929102002006	phosphorylation site [posttranslational modification]
929102002007	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
929102002008	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
929102002009	HPr interaction site; other site
929102002010	glycerol kinase (GK) interaction site [polypeptide binding]; other site
929102002011	active site
929102002012	phosphorylation site [posttranslational modification]
929102002013	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
929102002014	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
929102002015	nucleotide binding site [chemical binding]; other site
929102002016	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
929102002017	DNA-binding site [nucleotide binding]; DNA binding site
929102002018	RNA-binding motif; other site
929102002019	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
929102002020	DNA-binding site [nucleotide binding]; DNA binding site
929102002021	RNA-binding motif; other site
929102002022	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
929102002023	Helix-turn-helix domain; Region: HTH_28; pfam13518
929102002024	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
929102002025	Homeodomain-like domain; Region: HTH_23; cl17451
929102002026	HsdM N-terminal domain; Region: HsdM_N; pfam12161
929102002027	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
929102002028	Methyltransferase domain; Region: Methyltransf_26; pfam13659
929102002029	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
929102002030	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
929102002031	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
929102002032	type I site-specific deoxyribonuclease, HsdR family; Region: hsdR; TIGR00348
929102002033	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
929102002034	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
929102002035	ATP binding site [chemical binding]; other site
929102002036	putative Mg++ binding site [ion binding]; other site
929102002037	Type I restriction and modification enzyme - subunit R C terminal; Region: EcoR124_C; pfam12008
929102002038	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4487
929102002039	Uncharacterized protein conserved in bacteria (DUF2130); Region: DUF2130; pfam09903
929102002040	AAA domain; Region: AAA_23; pfam13476
929102002041	AAA domain; Region: AAA_21; pfam13304
929102002042	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929102002043	ABC transporter signature motif; other site
929102002044	Walker B; other site
929102002045	D-loop; other site
929102002046	H-loop/switch region; other site
929102002047	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
929102002048	Transposase; Region: DDE_Tnp_ISL3; pfam01610
929102002049	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
929102002050	HSP70 interaction site [polypeptide binding]; other site
929102002051	Domain of unknown function (DUF955); Region: DUF955; pfam06114
929102002052	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929102002053	non-specific DNA binding site [nucleotide binding]; other site
929102002054	salt bridge; other site
929102002055	sequence-specific DNA binding site [nucleotide binding]; other site
929102002056	Bacterial protein of unknown function (DUF961); Region: DUF961; pfam06125
929102002057	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
929102002058	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
929102002059	Bacteriophage abortive infection AbiH; Region: AbiH; pfam14253
929102002060	Replication initiation factor; Region: Rep_trans; pfam02486
929102002061	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
929102002062	Conjugative transposon protein TcpC; Region: TpcC; pfam12642
929102002063	TcpE family; Region: TcpE; pfam12648
929102002064	AAA-like domain; Region: AAA_10; pfam12846
929102002065	Domain of unknown function DUF87; Region: DUF87; pfam01935
929102002066	Protein of unknown function (DUF1043); Region: DUF1043; cl11473
929102002067	CHAP domain; Region: CHAP; pfam05257
929102002068	Antirestriction protein (ArdA); Region: ArdA; pfam07275
929102002069	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
929102002070	Tn1545-related conjugative transposon integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes bacterial (gram positive) and phage integrases, including those similar to Tn1545, Tn5252, and...; Region: INT_Tn1545_C; cd01199
929102002071	Int/Topo IB signature motif; other site
929102002072	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
929102002073	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
929102002074	active site
929102002075	topology modulation protein; Reviewed; Region: PRK08118
929102002076	AAA domain; Region: AAA_17; pfam13207
929102002077	ribonuclease M5; Region: 5S_RNA_mat_M5; TIGR00334
929102002078	TOPRIM_ RNase M5_like: The topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain found in Ribonuclease M5: (RNase M5) and other small primase-like proteins from bacteria and archaea.  RNase M5 catalyzes the maturation of 5S rRNA in low...; Region: TOPRIM_RNase_M5_like; cd01027
929102002079	putative active site [active]
929102002080	putative metal binding site [ion binding]; other site
929102002081	Domain of unknown function (DUF4093); Region: DUF4093; pfam13331
929102002082	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
929102002083	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
929102002084	S-adenosylmethionine binding site [chemical binding]; other site
929102002085	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
929102002086	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
929102002087	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
929102002088	active site
929102002089	elongation factor P; Validated; Region: PRK00529
929102002090	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
929102002091	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
929102002092	RNA binding site [nucleotide binding]; other site
929102002093	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
929102002094	RNA binding site [nucleotide binding]; other site
929102002095	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1302
929102002096	Transcription termination factor [Transcription]; Region: NusB; COG0781
929102002097	4-alpha-glucanotransferase; Region: Glyco_hydro_77; cl00711
929102002098	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK05293
929102002099	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
929102002100	ligand binding site; other site
929102002101	oligomer interface; other site
929102002102	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
929102002103	dimer interface [polypeptide binding]; other site
929102002104	N-terminal domain interface [polypeptide binding]; other site
929102002105	sulfate 1 binding site; other site
929102002106	glucose-1-phosphate adenylyltransferase, GlgD subunit; Region: glgD; TIGR02092
929102002107	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
929102002108	ligand binding site; other site
929102002109	oligomer interface; other site
929102002110	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
929102002111	dimer interface [polypeptide binding]; other site
929102002112	N-terminal domain interface [polypeptide binding]; other site
929102002113	sulfate 1 binding site; other site
929102002114	glycogen synthase; Provisional; Region: glgA; PRK00654
929102002115	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
929102002116	ADP-binding pocket [chemical binding]; other site
929102002117	homodimer interface [polypeptide binding]; other site
929102002118	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
929102002119	homodimer interface [polypeptide binding]; other site
929102002120	glycogen/starch/alpha-glucan phosphorylases; Region: P_ylase; TIGR02093
929102002121	active site pocket [active]
929102002122	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
929102002123	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
929102002124	active site
929102002125	homodimer interface [polypeptide binding]; other site
929102002126	catalytic site [active]
929102002127	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
929102002128	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929102002129	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
929102002130	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
929102002131	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
929102002132	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
929102002133	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
929102002134	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydD; COG4988
929102002135	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929102002136	Walker A/P-loop; other site
929102002137	ATP binding site [chemical binding]; other site
929102002138	Q-loop/lid; other site
929102002139	ABC transporter signature motif; other site
929102002140	Walker B; other site
929102002141	D-loop; other site
929102002142	H-loop/switch region; other site
929102002143	ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydC; COG4987
929102002144	ATP-binding cassette domain of CydCD, subfamily C; Region: ABCC_cytochrome_bd; cd03247
929102002145	Walker A/P-loop; other site
929102002146	ATP binding site [chemical binding]; other site
929102002147	Q-loop/lid; other site
929102002148	ABC transporter signature motif; other site
929102002149	Walker B; other site
929102002150	D-loop; other site
929102002151	H-loop/switch region; other site
929102002152	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
929102002153	putative Zn2+ binding site [ion binding]; other site
929102002154	putative DNA binding site [nucleotide binding]; other site
929102002155	Helix-turn-helix diphteria tox regulatory element; Region: HTH_DTXR; smart00529
929102002156	Flavodoxin [Energy production and conversion / Coenzyme metabolism]; Region: HemG; COG4635
929102002157	NnaC (CMP-NeuNAc synthetase) _like subfamily of SGNH_hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: NnaC_like; cd01841
929102002158	active site
929102002159	catalytic triad [active]
929102002160	oxyanion hole [active]
929102002161	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
929102002162	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
929102002163	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929102002164	Walker A/P-loop; other site
929102002165	ATP binding site [chemical binding]; other site
929102002166	Q-loop/lid; other site
929102002167	ABC transporter signature motif; other site
929102002168	Walker B; other site
929102002169	D-loop; other site
929102002170	H-loop/switch region; other site
929102002171	Predicted integral membrane protein [Function unknown]; Region: COG3548
929102002172	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
929102002173	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
929102002174	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
929102002175	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
929102002176	Walker A/P-loop; other site
929102002177	ATP binding site [chemical binding]; other site
929102002178	Q-loop/lid; other site
929102002179	ABC transporter signature motif; other site
929102002180	Walker B; other site
929102002181	D-loop; other site
929102002182	H-loop/switch region; other site
929102002183	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
929102002184	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
929102002185	FtsX-like permease family; Region: FtsX; pfam02687
929102002186	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082); Region: DUF2082; pfam09855
929102002187	Predicted membrane protein [Function unknown]; Region: COG3619
929102002188	Arginate lyase and other MDR family members; Region: AL_MDR; cd08252
929102002189	zinc-binding alcohol dehydrogenase family protein; Region: adh_fam_1; TIGR02817
929102002190	putative NAD(P) binding site [chemical binding]; other site
929102002191	dimer interface [polypeptide binding]; other site
929102002192	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
929102002193	substrate binding site [chemical binding]; other site
929102002194	THF binding site; other site
929102002195	zinc-binding site [ion binding]; other site
929102002196	Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only]; Region: ElaC; COG1234
929102002197	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
929102002198	phosphoprotein phosphatases of the metallophosphatase superfamily, metallophosphatase domain; Region: MPP_PPP_family; cd00144
929102002199	active site
929102002200	metal binding site [ion binding]; metal-binding site
929102002201	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
929102002202	nucleoside/Zn binding site; other site
929102002203	dimer interface [polypeptide binding]; other site
929102002204	catalytic motif [active]
929102002205	putative transposase OrfB; Reviewed; Region: PHA02517
929102002206	HTH-like domain; Region: HTH_21; pfam13276
929102002207	Integrase core domain; Region: rve; pfam00665
929102002208	Integrase core domain; Region: rve_3; pfam13683
929102002209	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
929102002210	Transposase; Region: HTH_Tnp_1; pfam01527
929102002211	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
929102002212	Helix-turn-helix domain; Region: HTH_38; pfam13936
929102002213	Integrase core domain; Region: rve; pfam00665
929102002214	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
929102002215	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
929102002216	dimer interface [polypeptide binding]; other site
929102002217	conserved gate region; other site
929102002218	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
929102002219	ABC-ATPase subunit interface; other site
929102002220	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
929102002221	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
929102002222	Protein of unknown function, DUF624; Region: DUF624; pfam04854
929102002223	Transcriptional regulators [Transcription]; Region: PurR; COG1609
929102002224	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
929102002225	DNA binding site [nucleotide binding]
929102002226	domain linker motif; other site
929102002227	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
929102002228	dimerization interface [polypeptide binding]; other site
929102002229	ligand binding site [chemical binding]; other site
929102002230	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
929102002231	CoenzymeA binding site [chemical binding]; other site
929102002232	subunit interaction site [polypeptide binding]; other site
929102002233	PHB binding site; other site
929102002234	N-acylamino acid racemase (NAAAR), an octameric enzyme that catalyzes the racemization of N-acylamino acids. NAAARs act on a broad range of N-acylamino acids rather than amino acids. Enantiopure amino acids are of industrial interest as chiral building...; Region: NAAAR; cd03317
929102002235	o-succinylbenzoate synthase; Region: menC_lowGC/arch; TIGR01928
929102002236	active site
929102002237	octamer interface [polypeptide binding]; other site
929102002238	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
929102002239	O-succinylbenzoate-CoA ligase; Region: menE; TIGR01923
929102002240	acyl-activating enzyme (AAE) consensus motif; other site
929102002241	putative AMP binding site [chemical binding]; other site
929102002242	putative active site [active]
929102002243	putative CoA binding site [chemical binding]; other site
929102002244	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
929102002245	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
929102002246	substrate binding site [chemical binding]; other site
929102002247	oxyanion hole (OAH) forming residues; other site
929102002248	trimer interface [polypeptide binding]; other site
929102002249	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Region: menH_SHCHC; TIGR03695
929102002250	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
929102002251	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase [Coenzyme metabolism]; Region: MenD; COG1165
929102002252	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
929102002253	dimer interface [polypeptide binding]; other site
929102002254	tetramer interface [polypeptide binding]; other site
929102002255	PYR/PP interface [polypeptide binding]; other site
929102002256	TPP binding site [chemical binding]; other site
929102002257	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
929102002258	TPP-binding site; other site
929102002259	Isochorismate synthase [Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: MenF; COG1169
929102002260	isochorismate synthases; Region: isochor_syn; TIGR00543
929102002261	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
929102002262	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
929102002263	Predicted transcriptional regulator containing CBS domains [Transcription]; Region: COG4109
929102002264	DRTGG domain; Region: DRTGG; pfam07085
929102002265	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with a DRTGG domain upstream. The function of the DRTGG domain, named after its conserved residues, is unknown. CBS is a small domain originally...; Region: CBS_pair_DRTGG_assoc; cd04596
929102002266	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
929102002267	DHH family; Region: DHH; pfam01368
929102002268	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
929102002269	active site
929102002270	homotetramer interface [polypeptide binding]; other site
929102002271	homodimer interface [polypeptide binding]; other site
929102002272	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
929102002273	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
929102002274	active site
929102002275	motif I; other site
929102002276	motif II; other site
929102002277	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
929102002278	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4696
929102002279	metal binding site [ion binding]; metal-binding site
929102002280	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
929102002281	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
929102002282	aspartate kinase; Reviewed; Region: PRK09034
929102002283	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
929102002284	nucleotide binding site [chemical binding]; other site
929102002285	substrate binding site [chemical binding]; other site
929102002286	ACT domains located C-terminal to the catalytic domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-YclM-BS_1; cd04911
929102002287	allosteric regulatory residue; other site
929102002288	ACT domains located C-terminal to the catalytic domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-YclM-BS_2; cd04916
929102002289	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
929102002290	Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396
929102002291	active site
929102002292	nucleophile elbow; other site
929102002293	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
929102002294	MarR family; Region: MarR_2; pfam12802
929102002295	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
929102002296	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
929102002297	motif II; other site
929102002298	Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain [Signal transduction mechanisms]; Region: COG3887
929102002299	DHH family; Region: DHH; pfam01368
929102002300	DHHA1 domain; Region: DHHA1; pfam02272
929102002301	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
929102002302	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
929102002303	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
929102002304	replicative DNA helicase; Provisional; Region: PRK05748
929102002305	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
929102002306	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
929102002307	Walker A motif; other site
929102002308	ATP binding site [chemical binding]; other site
929102002309	Walker B motif; other site
929102002310	DNA binding loops [nucleotide binding]
929102002311	Uncharacterized protein conserved in bacteria [Function unknown]; Region: Veg; COG4466
929102002312	Phosphotransferase enzyme family; Region: APH; pfam01636
929102002313	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
929102002314	active site
929102002315	ATP binding site [chemical binding]; other site
929102002316	substrate binding site [chemical binding]; other site
929102002317	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929102002318	S-adenosylmethionine binding site [chemical binding]; other site
929102002319	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
929102002320	Transcription factor S-II (TFIIS); Region: TFIIS_C; cl02609
929102002321	ATP cone domain; Region: ATP-cone; pfam03477
929102002322	Replication initiation/membrane attachment protein [DNA replication, recombination, and repair]; Region: DnaB; COG3611
929102002323	Replication initiation and membrane attachment; Region: DnaB_2; cl12121
929102002324	primosomal protein DnaI; Reviewed; Region: PRK08939
929102002325	Primosomal protein DnaI N-terminus; Region: DnaI_N; pfam07319
929102002326	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929102002327	Walker A motif; other site
929102002328	ATP binding site [chemical binding]; other site
929102002329	Walker B motif; other site
929102002330	arginine finger; other site
929102002331	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
929102002332	dimer interface [polypeptide binding]; other site
929102002333	FMN binding site [chemical binding]; other site
929102002334	NADPH bind site [chemical binding]; other site
929102002335	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
929102002336	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
929102002337	GTP-binding protein Der; Reviewed; Region: PRK00093
929102002338	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
929102002339	G1 box; other site
929102002340	GTP/Mg2+ binding site [chemical binding]; other site
929102002341	Switch I region; other site
929102002342	G2 box; other site
929102002343	Switch II region; other site
929102002344	G3 box; other site
929102002345	G4 box; other site
929102002346	G5 box; other site
929102002347	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
929102002348	G1 box; other site
929102002349	GTP/Mg2+ binding site [chemical binding]; other site
929102002350	Switch I region; other site
929102002351	G2 box; other site
929102002352	G3 box; other site
929102002353	Switch II region; other site
929102002354	G4 box; other site
929102002355	G5 box; other site
929102002356	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
929102002357	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929102002358	non-specific DNA binding site [nucleotide binding]; other site
929102002359	salt bridge; other site
929102002360	sequence-specific DNA binding site [nucleotide binding]; other site
929102002361	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
929102002362	Sortase C (SrtC) or subfamily-3 sortases are membrane cysteine transpeptidases found in Gram-positive bacteria that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. This involves a transpeptidation reaction in which the...; Region: Sortase_C_3; cd05827
929102002363	active site
929102002364	catalytic site [active]
929102002365	Protein of unknown function (DUF3990); Region: DUF3990; pfam13151
929102002366	Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346
929102002367	Putative effector of murein hydrolase LrgA [General function prediction only]; Region: COG1380
929102002368	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG0779
929102002369	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
929102002370	putative oligomer interface [polypeptide binding]; other site
929102002371	putative RNA binding site [nucleotide binding]; other site
929102002372	transcription elongation factor NusA; Provisional; Region: nusA; PRK12327
929102002373	NusA N-terminal domain; Region: NusA_N; pfam08529
929102002374	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
929102002375	RNA binding site [nucleotide binding]; other site
929102002376	homodimer interface [polypeptide binding]; other site
929102002377	NusA-like KH domain; Region: KH_5; pfam13184
929102002378	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
929102002379	G-X-X-G motif; other site
929102002380	Ylxr homologs; group of conserved hypothetical bacterial proteins of unknown function; structure revealed putative RNA binding cleft; proteins are encoded by an operon that includes other proteins involved in transcription and/or translation; Region: YlxR; cd00279
929102002381	putative RNA binding cleft [nucleotide binding]; other site
929102002382	hypothetical protein; Provisional; Region: PRK07283
929102002383	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
929102002384	translation initiation factor IF-2; Region: IF-2; TIGR00487
929102002385	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
929102002386	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
929102002387	G1 box; other site
929102002388	putative GEF interaction site [polypeptide binding]; other site
929102002389	GTP/Mg2+ binding site [chemical binding]; other site
929102002390	Switch I region; other site
929102002391	G2 box; other site
929102002392	G3 box; other site
929102002393	Switch II region; other site
929102002394	G4 box; other site
929102002395	G5 box; other site
929102002396	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
929102002397	Translation-initiation factor 2; Region: IF-2; pfam11987
929102002398	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
929102002399	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
929102002400	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
929102002401	mannose-6-phosphate isomerase, class I; Region: manA; TIGR00218
929102002402	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
929102002403	MarR family; Region: MarR; pfam01047
929102002404	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
929102002405	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
929102002406	dimer interface [polypeptide binding]; other site
929102002407	active site
929102002408	CoA binding pocket [chemical binding]; other site
929102002409	acyl carrier protein; Provisional; Region: acpP; PRK00982
929102002410	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
929102002411	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
929102002412	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
929102002413	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
929102002414	NAD(P) binding site [chemical binding]; other site
929102002415	homotetramer interface [polypeptide binding]; other site
929102002416	homodimer interface [polypeptide binding]; other site
929102002417	active site
929102002418	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
929102002419	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
929102002420	dimer interface [polypeptide binding]; other site
929102002421	active site
929102002422	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
929102002423	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
929102002424	carboxyltransferase (CT) interaction site; other site
929102002425	biotinylation site [posttranslational modification]; other site
929102002426	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
929102002427	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
929102002428	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
929102002429	ATP-grasp domain; Region: ATP-grasp_4; cl17255
929102002430	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
929102002431	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
929102002432	DNA directed RNA polymerase, 7 kDa subunit; Region: DNA_RNApol_7kD; cl00874
929102002433	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
929102002434	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; COG0825
929102002435	cystathionine gamma-synthase/cystathionine beta-lyase; Validated; Region: PRK06176
929102002436	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
929102002437	homodimer interface [polypeptide binding]; other site
929102002438	substrate-cofactor binding pocket; other site
929102002439	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929102002440	catalytic residue [active]
929102002441	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
929102002442	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
929102002443	dimer interface [polypeptide binding]; other site
929102002444	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929102002445	catalytic residue [active]
929102002446	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3237
929102002447	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
929102002448	active site residue [active]
929102002449	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
929102002450	active site residue [active]
929102002451	Uncharacterized protein YrkD from Bacillus subtilis and related domains; this domain superfamily was previously known as part of DUF156; Region: BsYrkD-like_DUF156; cd10155
929102002452	putative homodimer interface [polypeptide binding]; other site
929102002453	putative homotetramer interface [polypeptide binding]; other site
929102002454	putative metal binding site [ion binding]; other site
929102002455	putative homodimer-homodimer interface [polypeptide binding]; other site
929102002456	putative allosteric switch controlling residues; other site
929102002457	Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX)...; Region: ArsC_like; cd03036
929102002458	ArsC family; Region: ArsC; pfam03960
929102002459	putative ArsC-like catalytic residues; other site
929102002460	putative TRX-like catalytic residues [active]
929102002461	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
929102002462	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
929102002463	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
929102002464	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
929102002465	Human Ape1-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Ape1-like_AP-endo; cd09087
929102002466	active site
929102002467	putative catalytic site [active]
929102002468	DNA binding site [nucleotide binding]
929102002469	putative phosphate binding site [ion binding]; other site
929102002470	metal binding site A [ion binding]; metal-binding site
929102002471	AP binding site [nucleotide binding]; other site
929102002472	metal binding site B [ion binding]; metal-binding site
929102002473	methionyl-tRNA synthetase; Reviewed; Region: PRK12267
929102002474	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
929102002475	active site
929102002476	HIGH motif; other site
929102002477	KMSKS motif; other site
929102002478	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
929102002479	tRNA binding surface [nucleotide binding]; other site
929102002480	anticodon binding site; other site
929102002481	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
929102002482	dimer interface [polypeptide binding]; other site
929102002483	putative tRNA-binding site [nucleotide binding]; other site
929102002484	Protein of unknown function (DUF2829); Region: DUF2829; pfam11195
929102002485	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK06550
929102002486	classical (c) SDRs; Region: SDR_c; cd05233
929102002487	NAD(P) binding site [chemical binding]; other site
929102002488	active site
929102002489	Predicted membrane protein [Function unknown]; Region: COG4708
929102002490	biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs; Region: BVR-B_like_SDR_a; cd05244
929102002491	NADH(P)-binding; Region: NAD_binding_10; pfam13460
929102002492	NAD binding site [chemical binding]; other site
929102002493	substrate binding site [chemical binding]; other site
929102002494	putative active site [active]
929102002495	N-acetyl-gamma-glutamyl-phosphate reductase, common form; Region: argC; TIGR01850
929102002496	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
929102002497	Ornithine acetyltransferase (OAT) family; also referred to as ArgJ. OAT catalyzes the first and fifth steps in arginine biosynthesis, coupling acetylation of glutamate with deacetylation of N-acetylornithine, which allows recycling of the acetyl group in...; Region: OAT; cd02152
929102002498	heterotetramer interface [polypeptide binding]; other site
929102002499	active site pocket [active]
929102002500	cleavage site
929102002501	acetylornithine aminotransferase; Provisional; Region: argD; PRK02936
929102002502	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
929102002503	inhibitor-cofactor binding pocket; inhibition site
929102002504	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929102002505	catalytic residue [active]
929102002506	AAK_NAGK-C: N-Acetyl-L-glutamate kinase - cyclic (NAGK-C) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine biosynthesis found in some bacteria and photosynthetic organisms using the...; Region: AAK_NAGK-C; cd04250
929102002507	feedback inhibition sensing region; other site
929102002508	homohexameric interface [polypeptide binding]; other site
929102002509	nucleotide binding site [chemical binding]; other site
929102002510	N-acetyl-L-glutamate binding site [chemical binding]; other site
929102002511	ornithine carbamoyltransferase; Validated; Region: PRK02102
929102002512	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
929102002513	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
929102002514	ribonuclease III; Reviewed; Region: rnc; PRK00102
929102002515	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
929102002516	dimerization interface [polypeptide binding]; other site
929102002517	active site
929102002518	metal binding site [ion binding]; metal-binding site
929102002519	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
929102002520	dsRNA binding site [nucleotide binding]; other site
929102002521	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
929102002522	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
929102002523	Walker A/P-loop; other site
929102002524	ATP binding site [chemical binding]; other site
929102002525	Q-loop/lid; other site
929102002526	SMC proteins Flexible Hinge Domain; Region: SMC_hinge; smart00968
929102002527	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
929102002528	ABC transporter signature motif; other site
929102002529	Walker B; other site
929102002530	D-loop; other site
929102002531	H-loop/switch region; other site
929102002532	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
929102002533	Sulfatase; Region: Sulfatase; cl17466
929102002534	Predicted multitransmembrane protein [Function unknown]; Region: COG5438
929102002535	Predicted multitransmembrane protein [Function unknown]; Region: COG5438
929102002536	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
929102002537	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
929102002538	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
929102002539	active site
929102002540	motif I; other site
929102002541	motif II; other site
929102002542	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
929102002543	Protein of unknown function (DUF3159); Region: DUF3159; pfam11361
929102002544	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
929102002545	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
929102002546	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
929102002547	P loop; other site
929102002548	GTP binding site [chemical binding]; other site
929102002549	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK02269
929102002550	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
929102002551	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
929102002552	active site
929102002553	Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2508
929102002554	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
929102002555	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
929102002556	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
929102002557	HIGH motif; other site
929102002558	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
929102002559	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
929102002560	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
929102002561	active site
929102002562	KMSKS motif; other site
929102002563	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
929102002564	tRNA binding surface [nucleotide binding]; other site
929102002565	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
929102002566	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
929102002567	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
929102002568	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
929102002569	putative active site [active]
929102002570	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
929102002571	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
929102002572	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
929102002573	beta-galactosidase; Region: BGL; TIGR03356
929102002574	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
929102002575	Lipase (class 2); Region: Lipase_2; pfam01674
929102002576	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
929102002577	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
929102002578	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
929102002579	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
929102002580	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
929102002581	L-serine dehydratase, iron-sulfur-dependent, beta subunit; Region: sda_beta; TIGR00719
929102002582	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
929102002583	C-terminal ACT domain of the L-serine dehydratase (LSD), iron-sulfur-dependent, beta subunit; Region: ACT_LSD; cd04903
929102002584	putative L-serine binding site [chemical binding]; other site
929102002585	Serine dehydratase alpha chain; Region: SDH_alpha; cl12120
929102002586	L-serine deaminase [Amino acid transport and metabolism]; Region: SdaA; COG1760
929102002587	Predicted transcriptional regulator [Transcription]; Region: COG3682
929102002588	copper transport repressor, CopY/TcrY family; Region: CopY_TcrY; TIGR02698
929102002589	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
929102002590	metal-binding site [ion binding]
929102002591	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
929102002592	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
929102002593	metal-binding site [ion binding]
929102002594	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
929102002595	Soluble P-type ATPase [General function prediction only]; Region: COG4087
929102002596	Predicted membrane protein [Function unknown]; Region: COG4485
929102002597	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
929102002598	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
929102002599	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06676
929102002600	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
929102002601	RNA binding site [nucleotide binding]; other site
929102002602	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
929102002603	RNA binding site [nucleotide binding]; other site
929102002604	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
929102002605	RNA binding site [nucleotide binding]; other site
929102002606	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
929102002607	RNA binding site [nucleotide binding]; other site
929102002608	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
929102002609	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
929102002610	Nicotinamide mononucleotide transporter; Region: NMN_transporter; pfam04973
929102002611	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
929102002612	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
929102002613	GIY-YIG motif/motif A; other site
929102002614	active site
929102002615	catalytic site [active]
929102002616	putative DNA binding site [nucleotide binding]; other site
929102002617	metal binding site [ion binding]; metal-binding site
929102002618	UvrB/uvrC motif; Region: UVR; pfam02151
929102002619	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
929102002620	A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; Region: MutY; COG1194
929102002621	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
929102002622	minor groove reading motif; other site
929102002623	helix-hairpin-helix signature motif; other site
929102002624	substrate binding pocket [chemical binding]; other site
929102002625	active site
929102002626	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
929102002627	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
929102002628	DNA binding and oxoG recognition site [nucleotide binding]
929102002629	dipeptidase PepV; Region: dipeptidase; TIGR01886
929102002630	M20 Peptidase Xaa-His dipeptidase (PepV) degrades hydrophobic dipeptides; Region: M20_PepV; cd03888
929102002631	active site
929102002632	metal binding site [ion binding]; metal-binding site
929102002633	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
929102002634	alanine racemase; Reviewed; Region: alr; PRK00053
929102002635	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
929102002636	active site
929102002637	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
929102002638	dimer interface [polypeptide binding]; other site
929102002639	substrate binding site [chemical binding]; other site
929102002640	catalytic residues [active]
929102002641	Arsenate Reductase (ArsC) family, Spx subfamily; Spx is a unique RNA polymerase (RNAP)-binding protein present in bacilli and some mollicutes. It inhibits transcription by binding to the C-terminal domain of the alpha subunit of RNAP, disrupting complex...; Region: ArsC_Spx; cd03032
929102002642	ArsC family; Region: ArsC; pfam03960
929102002643	putative catalytic residues [active]
929102002644	thiol/disulfide switch; other site
929102002645	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes [Energy production and conversion]; Region: Lpd; COG1249
929102002646	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
929102002647	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
929102002648	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
929102002649	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929102002650	Walker A/P-loop; other site
929102002651	ATP binding site [chemical binding]; other site
929102002652	Q-loop/lid; other site
929102002653	ABC transporter signature motif; other site
929102002654	Walker B; other site
929102002655	D-loop; other site
929102002656	H-loop/switch region; other site
929102002657	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
929102002658	ABC-ATPase subunit interface; other site
929102002659	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
929102002660	copper-(or silver)-translocating P-type ATPase; Region: ATPase-IB1_Cu; TIGR01511
929102002661	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
929102002662	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
929102002663	KxYKxGKxW signal peptide; Region: KxYKxGKxW; TIGR03715
929102002664	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14179
929102002665	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
929102002666	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
929102002667	homodimer interface [polypeptide binding]; other site
929102002668	NADP binding site [chemical binding]; other site
929102002669	substrate binding site [chemical binding]; other site
929102002670	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
929102002671	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
929102002672	generic binding surface II; other site
929102002673	generic binding surface I; other site
929102002674	exodeoxyribonuclease VII, small subunit; Region: xseB; TIGR01280
929102002675	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
929102002676	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
929102002677	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
929102002678	substrate binding pocket [chemical binding]; other site
929102002679	chain length determination region; other site
929102002680	substrate-Mg2+ binding site; other site
929102002681	catalytic residues [active]
929102002682	aspartate-rich region 1; other site
929102002683	active site lid residues [active]
929102002684	aspartate-rich region 2; other site
929102002685	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
929102002686	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
929102002687	RNA binding surface [nucleotide binding]; other site
929102002688	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
929102002689	Arginine repressor [Transcription]; Region: ArgR; COG1438
929102002690	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
929102002691	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
929102002692	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
929102002693	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
929102002694	Walker A/P-loop; other site
929102002695	ATP binding site [chemical binding]; other site
929102002696	Q-loop/lid; other site
929102002697	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
929102002698	ABC transporter signature motif; other site
929102002699	Walker B; other site
929102002700	D-loop; other site
929102002701	H-loop/switch region; other site
929102002702	Predicted integral membrane protein [Function unknown]; Region: COG3548
929102002703	Predicted membrane protein [Function unknown]; Region: COG3152
929102002704	Predicted membrane protein [Function unknown]; Region: COG3152
929102002705	Predicted membrane protein [Function unknown]; Region: COG3152
929102002706	Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG0275
929102002707	MraW methylase family; Region: Methyltransf_5; pfam01795
929102002708	Protein required for the initiation of cell division [Cell division and chromosome partitioning]; Region: FtsL; COG4839
929102002709	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
929102002710	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
929102002711	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
929102002712	PASTA domain of PBP2x-like proteins, first repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_1; cd06576
929102002713	PASTA domain of PBP2x-like proteins, second repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_2; cd06575
929102002714	phospho-N-acetylmuramoyl-pentapeptide-transferase; Region: mraY; TIGR00445
929102002715	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
929102002716	Mg++ binding site [ion binding]; other site
929102002717	putative catalytic motif [active]
929102002718	putative substrate binding site [chemical binding]; other site
929102002719	FtsX-like permease family; Region: FtsX; pfam02687
929102002720	Transcriptional regulator [Transcription]; Region: LysR; COG0583
929102002721	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
929102002722	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
929102002723	dimerization interface [polypeptide binding]; other site
929102002724	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
929102002725	synthetase active site [active]
929102002726	NTP binding site [chemical binding]; other site
929102002727	metal binding site [ion binding]; metal-binding site
929102002728	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
929102002729	N-glycosyltransferase; Provisional; Region: PRK11204
929102002730	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
929102002731	DXD motif; other site
929102002732	Uncharacterized conserved protein [Function unknown]; Region: HdeD; COG3247
929102002733	nicotinamide mononucleotide transporter PnuC; Region: NMN_trans_PnuC; TIGR01528
929102002734	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
929102002735	Ligand Binding Site [chemical binding]; other site
929102002736	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
929102002737	IHF dimer interface [polypeptide binding]; other site
929102002738	IHF - DNA interface [nucleotide binding]; other site
929102002739	probable dihydroxyacetone kinase regulator; Region: DHAK_reg; TIGR02366
929102002740	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
929102002741	Predicted membrane protein [Function unknown]; Region: COG1511
929102002742	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
929102002743	YhgE/Pip C-terminal domain; Region: pip_yhgE_Cterm; TIGR03062
929102002744	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
929102002745	Bacterial cell division membrane protein [Cell division and chromosome partitioning]; Region: FtsW; COG0772
929102002746	Ribosomal protein S14p/S29e; Region: Ribosomal_S14; cl00355
929102002747	Predicted membrane protein [Function unknown]; Region: COG4758
929102002748	Cell wall-active antibiotics response protein (DUF2154); Region: DUF2154; pfam09922
929102002749	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
929102002750	Histidine kinase; Region: HisKA_3; pfam07730
929102002751	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929102002752	ATP binding site [chemical binding]; other site
929102002753	Mg2+ binding site [ion binding]; other site
929102002754	G-X-G motif; other site
929102002755	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
929102002756	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929102002757	active site
929102002758	phosphorylation site [posttranslational modification]
929102002759	intermolecular recognition site; other site
929102002760	dimerization interface [polypeptide binding]; other site
929102002761	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
929102002762	DNA binding residues [nucleotide binding]
929102002763	dimerization interface [polypeptide binding]; other site
929102002764	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
929102002765	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
929102002766	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
929102002767	active site
929102002768	Predicted RNA binding protein (contains ribosomal protein S1 domain) [Translation, ribosomal structure and biogenesis]; Region: VacB; COG1098
929102002769	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
929102002770	RNA binding site [nucleotide binding]; other site
929102002771	Uncharacterized conserved protein [Function unknown]; Region: COG0398
929102002772	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
929102002773	Bacterial cell division membrane protein [Cell division and chromosome partitioning]; Region: FtsW; COG0772
929102002774	acetoin reductase; Validated; Region: PRK08643
929102002775	meso-2,3-butanediol dehydrogenase-like, classical (c) SDRs; Region: meso-BDH-like_SDR_c; cd05366
929102002776	NAD binding site [chemical binding]; other site
929102002777	homotetramer interface [polypeptide binding]; other site
929102002778	homodimer interface [polypeptide binding]; other site
929102002779	active site
929102002780	substrate binding site [chemical binding]; other site
929102002781	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
929102002782	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
929102002783	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
929102002784	ABC transporter; Region: ABC_tran_2; pfam12848
929102002785	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
929102002786	malate dehydrogenase; Provisional; Region: PRK13529
929102002787	Malic enzyme, N-terminal domain; Region: malic; pfam00390
929102002788	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
929102002789	NAD(P) binding site [chemical binding]; other site
929102002790	2-hydroxycarboxylate transporter family; Region: 2HCT; cl01386
929102002791	EamA-like transporter family; Region: EamA; pfam00892
929102002792	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
929102002793	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
929102002794	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
929102002795	motif II; other site
929102002796	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
929102002797	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929102002798	Mg2+ binding site [ion binding]; other site
929102002799	G-X-G motif; other site
929102002800	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
929102002801	anchoring element; other site
929102002802	dimer interface [polypeptide binding]; other site
929102002803	ATP binding site [chemical binding]; other site
929102002804	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
929102002805	active site
929102002806	putative metal-binding site [ion binding]; other site
929102002807	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
929102002808	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
929102002809	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929102002810	S-adenosylmethionine binding site [chemical binding]; other site
929102002811	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
929102002812	MarR family; Region: MarR_2; pfam12802
929102002813	MarR family; Region: MarR_2; cl17246
929102002814	Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase [Carbohydrate transport and metabolism]; Region: EpsL; COG4632
929102002815	Ion channel; Region: Ion_trans_2; pfam07885
929102002816	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
929102002817	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
929102002818	Walker A/P-loop; other site
929102002819	ATP binding site [chemical binding]; other site
929102002820	Q-loop/lid; other site
929102002821	ABC transporter signature motif; other site
929102002822	Walker B; other site
929102002823	D-loop; other site
929102002824	H-loop/switch region; other site
929102002825	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
929102002826	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
929102002827	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
929102002828	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
929102002829	active site
929102002830	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
929102002831	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
929102002832	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
929102002833	Transposase; Region: HTH_Tnp_1; pfam01527
929102002834	putative transposase OrfB; Reviewed; Region: PHA02517
929102002835	HTH-like domain; Region: HTH_21; pfam13276
929102002836	Integrase core domain; Region: rve; pfam00665
929102002837	Integrase core domain; Region: rve_3; pfam13683
929102002838	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
929102002839	Cytidylyltransferase; Region: CTP_transf_2; pfam01467
929102002840	active site
929102002841	nucleotide binding site [chemical binding]; other site
929102002842	HIGH motif; other site
929102002843	KMSKS motif; other site
929102002844	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
929102002845	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; Region: Glyphos_transf; pfam04464
929102002846	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
929102002847	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; Region: Glyphos_transf; pfam04464
929102002848	Transcriptional regulator [Transcription]; Region: LytR; COG1316
929102002849	phosphopentomutase; Provisional; Region: PRK05362
929102002850	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
929102002851	Putative zinc ribbon domain; Region: Zn_ribbon_2; pfam12674
929102002852	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
929102002853	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
929102002854	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
929102002855	hypothetical protein; Provisional; Region: PRK00967
929102002856	formate--tetrahydrofolate ligase; Provisional; Region: PRK13505
929102002857	Formyltetrahydrofolate synthetase (FTHFS) catalyzes the ATP-dependent activation of formate ion via its addition to the N10 position of tetrahydrofolate. FTHFS is a highly expressed key enzyme in both the Wood-Ljungdahl pathway of autotrophic CO2...; Region: FTHFS; cd00477
929102002858	Potassium binding sites [ion binding]; other site
929102002859	Cesium cation binding sites [ion binding]; other site
929102002860	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
929102002861	NlpC/P60 family; Region: NLPC_P60; pfam00877
929102002862	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
929102002863	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
929102002864	substrate binding pocket [chemical binding]; other site
929102002865	membrane-bound complex binding site; other site
929102002866	hinge residues; other site
929102002867	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
929102002868	dimer interface [polypeptide binding]; other site
929102002869	conserved gate region; other site
929102002870	putative PBP binding loops; other site
929102002871	ABC-ATPase subunit interface; other site
929102002872	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
929102002873	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
929102002874	Walker A/P-loop; other site
929102002875	ATP binding site [chemical binding]; other site
929102002876	Q-loop/lid; other site
929102002877	ABC transporter signature motif; other site
929102002878	Walker B; other site
929102002879	D-loop; other site
929102002880	H-loop/switch region; other site
929102002881	Protein of unknown function (DUF4059); Region: DUF4059; pfam13268
929102002882	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
929102002883	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
929102002884	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
929102002885	Preprotein translocase subunit SecG [Intracellular trafficking and secretion]; Region: SecG; COG1314
929102002886	ribonuclease R; Region: RNase_R; TIGR02063
929102002887	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
929102002888	RNB domain; Region: RNB; pfam00773
929102002889	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
929102002890	RNA binding site [nucleotide binding]; other site
929102002891	Isochorismatase family; Region: Isochorismatase; pfam00857
929102002892	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
929102002893	catalytic triad [active]
929102002894	conserved cis-peptide bond; other site
929102002895	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
929102002896	putative catalytic site [active]
929102002897	putative metal binding site [ion binding]; other site
929102002898	putative phosphate binding site [ion binding]; other site
929102002899	1,4-dihydroxy-2-naphthoate octaprenyltransferase [Coenzyme metabolism]; Region: MenA; COG1575
929102002900	UbiA prenyltransferase family; Region: UbiA; pfam01040
929102002901	ACT domain proteins similar to the yet uncharacterized Streptococcus pneumoniae ACT domain protein; Region: ACT_1ZPV; cd04872
929102002902	Uncharacterized proteins with similarity to Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL_like_DUF711; cd08025
929102002903	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
929102002904	catalytic core [active]
929102002905	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
929102002906	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: VanY; COG1876
929102002907	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
929102002908	Transcriptional regulator of heat shock gene [Transcription]; Region: HrcA; COG1420
929102002909	Winged helix-turn-helix transcription repressor, HrcA DNA-binding; Region: HrcA_DNA-bdg; pfam03444
929102002910	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
929102002911	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
929102002912	dimer interface [polypeptide binding]; other site
929102002913	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
929102002914	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
929102002915	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
929102002916	nucleotide binding site [chemical binding]; other site
929102002917	NEF interaction site [polypeptide binding]; other site
929102002918	SBD interface [polypeptide binding]; other site
929102002919	Myosin-crossreactive antigen [Function unknown]; Region: COG4716
929102002920	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
929102002921	M20 Peptidase Aminoacyclase-1 YxeP-like proteins, including YxeP, YtnL, YjiB and HipO2; Region: M20_Acy1_YxeP_like; cd05669
929102002922	metal binding site [ion binding]; metal-binding site
929102002923	dimer interface [polypeptide binding]; other site
929102002924	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
929102002925	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
929102002926	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
929102002927	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
929102002928	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
929102002929	putative substrate binding site [chemical binding]; other site
929102002930	putative ATP binding site [chemical binding]; other site
929102002931	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
929102002932	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
929102002933	active site
929102002934	phosphorylation site [posttranslational modification]
929102002935	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
929102002936	active site
929102002937	P-loop; other site
929102002938	phosphorylation site [posttranslational modification]
929102002939	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
929102002940	cardiolipin synthase; Region: bac_cardiolipin; TIGR04265
929102002941	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
929102002942	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
929102002943	putative active site [active]
929102002944	catalytic site [active]
929102002945	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
929102002946	putative active site [active]
929102002947	catalytic site [active]
929102002948	Predicted P-loop-containing kinase [General function prediction only]; Region: COG1660
929102002949	AAA domain; Region: AAA_18; pfam13238
929102002950	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
929102002951	Family of CofD-like proteins and proteins related to YvcK; Region: CofD_YvcK; cd07044
929102002952	dimer interface [polypeptide binding]; other site
929102002953	phosphate binding site [ion binding]; other site
929102002954	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1481
929102002955	Sporulation Regulator WhiA N terminal; Region: WhiA_N; pfam10298
929102002956	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
929102002957	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
929102002958	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
929102002959	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
929102002960	Walker A/P-loop; other site
929102002961	ATP binding site [chemical binding]; other site
929102002962	Q-loop/lid; other site
929102002963	ABC transporter signature motif; other site
929102002964	Walker B; other site
929102002965	D-loop; other site
929102002966	H-loop/switch region; other site
929102002967	Domain of unknown function (DUF4162); Region: DUF4162; pfam13732
929102002968	Putative exporter of polyketide antibiotics [Cell envelope biogenesis, outer membrane]; Region: TnrB3; COG3559
929102002969	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
929102002970	hypothetical protein; Provisional; Region: PRK13662
929102002971	peptide chain release factor 2; Validated; Region: prfB; PRK00578
929102002972	This domain is found in peptide chain release factors; Region: PCRF; smart00937
929102002973	RF-1 domain; Region: RF-1; pfam00472
929102002974	Predicted ATPase involved in cell division [Cell division and chromosome partitioning]; Region: FtsE; COG2884
929102002975	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929102002976	Walker A/P-loop; other site
929102002977	ATP binding site [chemical binding]; other site
929102002978	Q-loop/lid; other site
929102002979	ABC transporter signature motif; other site
929102002980	Walker B; other site
929102002981	D-loop; other site
929102002982	H-loop/switch region; other site
929102002983	Cell division protein [Cell division and chromosome partitioning]; Region: FtsX; COG2177
929102002984	HD domain; Region: HD_3; cl17350
929102002985	FtsX-like permease family; Region: FtsX; pfam02687
929102002986	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
929102002987	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
929102002988	dimer interface [polypeptide binding]; other site
929102002989	putative radical transfer pathway; other site
929102002990	diiron center [ion binding]; other site
929102002991	tyrosyl radical; other site
929102002992	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK07306
929102002993	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
929102002994	Class I ribonucleotide reductase; Region: RNR_I; cd01679
929102002995	active site
929102002996	dimer interface [polypeptide binding]; other site
929102002997	catalytic residues [active]
929102002998	effector binding site; other site
929102002999	R2 peptide binding site; other site
929102003000	Protein involved in ribonucleotide reduction [Nucleotide transport and metabolism]; Region: NrdI; COG1780
929102003001	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
929102003002	catalytic residues [active]
929102003003	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
929102003004	DNA topoisomerase IV, B subunit, Gram-positive; Region: parE_Gpos; TIGR01058
929102003005	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929102003006	Mg2+ binding site [ion binding]; other site
929102003007	G-X-G motif; other site
929102003008	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
929102003009	anchoring element; other site
929102003010	dimer interface [polypeptide binding]; other site
929102003011	ATP binding site [chemical binding]; other site
929102003012	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
929102003013	active site
929102003014	putative metal-binding site [ion binding]; other site
929102003015	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
929102003016	Isochorismatase family; Region: Isochorismatase; pfam00857
929102003017	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
929102003018	catalytic triad [active]
929102003019	conserved cis-peptide bond; other site
929102003020	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
929102003021	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
929102003022	active site
929102003023	catalytic site [active]
929102003024	substrate binding site [chemical binding]; other site
929102003025	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929102003026	Coenzyme A binding pocket [chemical binding]; other site
929102003027	DNA topoisomerase IV, A subunit, Gram-positive; Region: parC_Gpos; TIGR01061
929102003028	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
929102003029	CAP-like domain; other site
929102003030	active site
929102003031	primary dimer interface [polypeptide binding]; other site
929102003032	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
929102003033	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
929102003034	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
929102003035	uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u2; cd12827
929102003036	oligomer interface [polypeptide binding]; other site
929102003037	Cl binding site [ion binding]; other site
929102003038	KxYKxGKxW signal peptide; Region: KxYKxGKxW; TIGR03715
929102003039	riboflavin biosynthesis protein RibD; Region: eubact_ribD; TIGR00326
929102003040	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
929102003041	catalytic motif [active]
929102003042	Zn binding site [ion binding]; other site
929102003043	RibD C-terminal domain; Region: RibD_C; cl17279
929102003044	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
929102003045	Lumazine binding domain; Region: Lum_binding; pfam00677
929102003046	Lumazine binding domain; Region: Lum_binding; pfam00677
929102003047	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09311
929102003048	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
929102003049	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
929102003050	dimerization interface [polypeptide binding]; other site
929102003051	active site
929102003052	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
929102003053	homopentamer interface [polypeptide binding]; other site
929102003054	active site
929102003055	lipoprotein signal peptidase; Provisional; Region: PRK14797
929102003056	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
929102003057	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
929102003058	RNA binding surface [nucleotide binding]; other site
929102003059	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
929102003060	active site
929102003061	Divergent PAP2 family; Region: DUF212; pfam02681
929102003062	conserved hypothetical integral membrane protein; Region: TIGR03766
929102003063	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
929102003064	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
929102003065	Ligand binding site; other site
929102003066	Putative Catalytic site; other site
929102003067	DXD motif; other site
929102003068	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
929102003069	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929102003070	active site
929102003071	phosphorylation site [posttranslational modification]
929102003072	intermolecular recognition site; other site
929102003073	dimerization interface [polypeptide binding]; other site
929102003074	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
929102003075	DNA binding site [nucleotide binding]
929102003076	Predicted membrane protein [Function unknown]; Region: COG4331
929102003077	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
929102003078	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
929102003079	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
929102003080	dimer interface [polypeptide binding]; other site
929102003081	phosphorylation site [posttranslational modification]
929102003082	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929102003083	ATP binding site [chemical binding]; other site
929102003084	Mg2+ binding site [ion binding]; other site
929102003085	G-X-G motif; other site
929102003086	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
929102003087	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
929102003088	active site
929102003089	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
929102003090	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
929102003091	glutaminase active site [active]
929102003092	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
929102003093	dimer interface [polypeptide binding]; other site
929102003094	active site
929102003095	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
929102003096	dimer interface [polypeptide binding]; other site
929102003097	active site
929102003098	DNA repair proteins [DNA replication, recombination, and repair]; Region: RadC; COG2003
929102003099	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
929102003100	MPN+ (JAMM) motif; other site
929102003101	Zinc-binding site [ion binding]; other site
929102003102	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
929102003103	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
929102003104	Int/Topo IB signature motif; other site
929102003105	Domain of unknown function (DUF955); Region: DUF955; pfam06114
929102003106	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929102003107	non-specific DNA binding site [nucleotide binding]; other site
929102003108	salt bridge; other site
929102003109	sequence-specific DNA binding site [nucleotide binding]; other site
929102003110	Phage anti-repressor protein [Transcription]; Region: COG3561
929102003111	ORF6C domain; Region: ORF6C; pfam10552
929102003112	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4707
929102003113	putative transcription regulator; Provisional; Region: PHA02503
929102003114	PDDEXK-like domain of unknown function (DUF3799); Region: DUF3799; pfam12684
929102003115	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
929102003116	Walker A motif; other site
929102003117	ATP binding site [chemical binding]; other site
929102003118	Walker B motif; other site
929102003119	Helix-turn-helix domain; Region: HTH_36; pfam13730
929102003120	Holliday junction resolvase [DNA replication, recombination, and repair]; Region: Rus; COG4570
929102003121	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
929102003122	DNA methylase; Region: N6_N4_Mtase; pfam01555
929102003123	Protein of unknown function (DUF1031); Region: DUF1031; pfam06275
929102003124	Protein of unknown function (DUF1642); Region: DUF1642; pfam07852
929102003125	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
929102003126	trimer interface [polypeptide binding]; other site
929102003127	active site
929102003128	Protein of unknown function (DUF722); Region: DUF722; pfam05263
929102003129	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5410
929102003130	Terminase-like family; Region: Terminase_6; pfam03237
929102003131	Phage-related terminase [General function prediction only]; Region: COG5362; cl02216
929102003132	Phage-related protein [Function unknown]; Region: COG4695; cl01923
929102003133	Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072
929102003134	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
929102003135	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
929102003136	Head-Tail Connector Proteins gp6 and gp15, and similar proteins; Region: gp6_gp15_like; cl12049
929102003137	Minor capsid protein; Region: Minor_capsid_1; pfam10665
929102003138	Minor capsid protein from bacteriophage; Region: Minor_capsid_3; pfam12691
929102003139	PAS fold; Region: PAS_7; pfam12860
929102003140	Bacteriophage Gp15 protein; Region: Phage_Gp15; pfam06854
929102003141	Phage-related protein [Function unknown]; Region: COG5412
929102003142	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
929102003143	Phage tail protein; Region: Sipho_tail; pfam05709
929102003144	Phage tail protein; Region: Sipho_tail; cl17486
929102003145	Prophage endopeptidase tail; Region: Prophage_tail; cl12123
929102003146	Phage lysis protein, holin; Region: Phage_holin; pfam04688
929102003147	Bacteriophage peptidoglycan hydrolase; Region: Amidase_5; pfam05382
929102003148	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
929102003149	AT-rich DNA-binding protein [General function prediction only]; Region: COG2344
929102003150	Putative DNA-binding protein N-terminus; Region: Put_DNA-bind_N; pfam06971
929102003151	CoA binding domain; Region: CoA_binding; pfam02629
929102003152	Arsenate Reductase (ArsC) family, Spx subfamily; Spx is a unique RNA polymerase (RNAP)-binding protein present in bacilli and some mollicutes. It inhibits transcription by binding to the C-terminal domain of the alpha subunit of RNAP, disrupting complex...; Region: ArsC_Spx; cd03032
929102003153	ArsC family; Region: ArsC; pfam03960
929102003154	putative catalytic residues [active]
929102003155	thiol/disulfide switch; other site
929102003156	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
929102003157	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
929102003158	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
929102003159	ABC transporter; Region: ABC_tran_2; pfam12848
929102003160	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
929102003161	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929102003162	non-specific DNA binding site [nucleotide binding]; other site
929102003163	salt bridge; other site
929102003164	sequence-specific DNA binding site [nucleotide binding]; other site
929102003165	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
929102003166	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
929102003167	active site
929102003168	dihydroorotase; Validated; Region: pyrC; PRK09357
929102003169	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
929102003170	Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317
929102003171	active site
929102003172	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
929102003173	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
929102003174	Putative primosome component and related proteins [DNA replication, recombination, and repair]; Region: DnaD; COG3935
929102003175	DnaD and phage-associated domain; Region: DnaD_dom; TIGR01446
929102003176	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
929102003177	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
929102003178	minor groove reading motif; other site
929102003179	helix-hairpin-helix signature motif; other site
929102003180	substrate binding pocket [chemical binding]; other site
929102003181	active site
929102003182	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; pfam10576
929102003183	Predicted SAM-dependent methyltransferase [General function prediction only]; Region: COG2384
929102003184	Family of unknown function (DUF633); Region: DUF633; pfam04816
929102003185	Uncharacterized conserved protein [Function unknown]; Region: COG0327
929102003186	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
929102003187	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4918
929102003188	sugar phosphate phosphatase; Provisional; Region: PRK10513
929102003189	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
929102003190	active site
929102003191	motif I; other site
929102003192	motif II; other site
929102003193	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
929102003194	HD superfamily phosphohydrolases [General function prediction only]; Region: COG1078
929102003195	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
929102003196	Zn2+ binding site [ion binding]; other site
929102003197	Mg2+ binding site [ion binding]; other site
929102003198	Domain of unknown function (DUF1934); Region: DUF1934; pfam09148
929102003199	Antidote-toxin recognition MazE; Region: Antitoxin-MazE; cl00877
929102003200	Predicted membrane protein [Function unknown]; Region: COG3371
929102003201	Protein of unknown function (DUF998); Region: DUF998; pfam06197
929102003202	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
929102003203	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
929102003204	Predicted ribosomal protein [Translation, ribosomal structure and biogenesis]; Region: COG2868
929102003205	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
929102003206	manganese transport protein MntH; Reviewed; Region: PRK00701
929102003207	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
929102003208	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
929102003209	PhoH-like protein; Region: PhoH; pfam02562
929102003210	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_18; cd04677
929102003211	nudix motif; other site
929102003212	metal-binding heat shock protein; Provisional; Region: PRK00016
929102003213	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
929102003214	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3575
929102003215	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
929102003216	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
929102003217	active site
929102003218	Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein) [DNA replication, recombination, and repair]; Region: comFA; COG4098
929102003219	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
929102003220	ATP binding site [chemical binding]; other site
929102003221	putative Mg++ binding site [ion binding]; other site
929102003222	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
929102003223	nucleotide binding region [chemical binding]; other site
929102003224	ATP-binding site [chemical binding]; other site
929102003225	Uncharacterized conserved protein [Function unknown]; Region: COG1739
929102003226	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
929102003227	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
929102003228	VanZ like family; Region: VanZ; pfam04892
929102003229	hypothetical protein; Provisional; Region: PRK14013
929102003230	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
929102003231	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
929102003232	active site
929102003233	metal binding site [ion binding]; metal-binding site
929102003234	glycyl-tRNA synthetase subunit alpha; Validated; Region: glyQ; PRK09348
929102003235	motif 1; other site
929102003236	dimer interface [polypeptide binding]; other site
929102003237	active site
929102003238	motif 2; other site
929102003239	motif 3; other site
929102003240	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
929102003241	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4224
929102003242	ClC sycA-like chloride channel proteins. This ClC family presents in bacteria, where it facilitates acid resistance in acidic soil. Mutation of this gene (sycA) in Rhizobium tropici CIAT899 causes serious deficiencies in nodule development, nodulation...; Region: ClC_sycA_like; cd03682
929102003243	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
929102003244	putative Cl- selectivity filter; other site
929102003245	putative pore gating glutamate residue; other site
929102003246	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
929102003247	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
929102003248	active site
929102003249	(T/H)XGH motif; other site
929102003250	nicotinate phosphoribosyltransferase; Validated; Region: PRK09243
929102003251	Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction...; Region: NAPRTase_A; cd01570
929102003252	active site
929102003253	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
929102003254	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929102003255	Coenzyme A binding pocket [chemical binding]; other site
929102003256	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
929102003257	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
929102003258	homodimer interface [polypeptide binding]; other site
929102003259	NAD binding pocket [chemical binding]; other site
929102003260	ATP binding pocket [chemical binding]; other site
929102003261	Mg binding site [ion binding]; other site
929102003262	active-site loop [active]
929102003263	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
929102003264	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
929102003265	Walker A/P-loop; other site
929102003266	ATP binding site [chemical binding]; other site
929102003267	Q-loop/lid; other site
929102003268	ABC transporter signature motif; other site
929102003269	Walker B; other site
929102003270	D-loop; other site
929102003271	H-loop/switch region; other site
929102003272	FtsX-like permease family; Region: FtsX; pfam02687
929102003273	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
929102003274	FtsX-like permease family; Region: FtsX; pfam02687
929102003275	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
929102003276	catalytic triad [active]
929102003277	UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurE; COG0769
929102003278	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
929102003279	Domain of unknown function (DUF1727); Region: DUF1727; pfam08353
929102003280	Alpha-acetolactate decarboxylase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: AlsD; COG3527
929102003281	GTP-binding protein LepA; Provisional; Region: PRK05433
929102003282	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
929102003283	G1 box; other site
929102003284	putative GEF interaction site [polypeptide binding]; other site
929102003285	GTP/Mg2+ binding site [chemical binding]; other site
929102003286	Switch I region; other site
929102003287	G2 box; other site
929102003288	G3 box; other site
929102003289	Switch II region; other site
929102003290	G4 box; other site
929102003291	G5 box; other site
929102003292	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
929102003293	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
929102003294	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
929102003295	NADH(P)-binding; Region: NAD_binding_10; pfam13460
929102003296	atypical (a) SDRs, subgroup 5; Region: SDR_a5; cd05243
929102003297	NAD(P) binding site [chemical binding]; other site
929102003298	putative active site [active]
929102003299	Amino acid permease; Region: AA_permease_2; pfam13520
929102003300	DNA gyrase subunit A; Validated; Region: PRK05560
929102003301	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
929102003302	CAP-like domain; other site
929102003303	active site
929102003304	primary dimer interface [polypeptide binding]; other site
929102003305	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
929102003306	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
929102003307	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
929102003308	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
929102003309	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
929102003310	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
929102003311	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
929102003312	ApbE family; Region: ApbE; pfam02424
929102003313	Sortase A (SrtA) or subfamily-1 sortases are cysteine transpeptidases found in gram-positive bacteria that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. They do so by catalyzing a transpeptidation reaction in which the...; Region: Sortase_A_1; cd06165
929102003314	active site
929102003315	catalytic site [active]
929102003316	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
929102003317	accessory Sec system protein Asp2; Region: acc_sec_asp2; TIGR03712
929102003318	Uncharacterized conserved protein [Function unknown]; Region: COG2898
929102003319	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
929102003320	Uncharacterized conserved protein (DUF2156); Region: DUF2156; pfam09924
929102003321	Lysyl-tRNA synthetase (class II) [Translation, ribosomal structure and biogenesis]; Region: LysU; COG1190
929102003322	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
929102003323	dimer interface [polypeptide binding]; other site
929102003324	putative anticodon binding site; other site
929102003325	Protein of unknown function (DUF998); Region: DUF998; pfam06197
929102003326	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
929102003327	Part of AAA domain; Region: AAA_19; pfam13245
929102003328	Family description; Region: UvrD_C_2; pfam13538
929102003329	MutT homolog-1 (MTH1) is a member of the Nudix hydrolase superfamily. MTH1, the mammalian counterpart of MutT, hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP and 2-hydroxy-ATP, to monophosphates, thereby preventing the...; Region: MTH1; cd03427
929102003330	putative active site [active]
929102003331	nucleotide binding site [chemical binding]; other site
929102003332	nudix motif; other site
929102003333	putative metal binding site [ion binding]; other site
929102003334	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
929102003335	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
929102003336	dimer interface [polypeptide binding]; other site
929102003337	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
929102003338	fumarate reductase flavoprotein subunit; Validated; Region: PRK06481
929102003339	L-aspartate oxidase; Provisional; Region: PRK06175
929102003340	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK02484
929102003341	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
929102003342	RNA binding site [nucleotide binding]; other site
929102003343	active site
929102003344	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
929102003345	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
929102003346	active site
929102003347	Riboflavin kinase; Region: Flavokinase; smart00904
929102003348	L-lactate dehydrogenase; Reviewed; Region: ldh; PRK00066
929102003349	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
929102003350	dimer interface [polypeptide binding]; other site
929102003351	tetramer (dimer of dimers) interface [polypeptide binding]; other site
929102003352	NAD binding site [chemical binding]; other site
929102003353	substrate binding site [chemical binding]; other site
929102003354	Uncharacterized conserved protein [Function unknown]; Region: COG3589
929102003355	Bacterial protein of unknown function (DUF871); Region: DUF871; pfam05913
929102003356	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
929102003357	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
929102003358	putative active site [active]
929102003359	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
929102003360	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
929102003361	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
929102003362	putative active site [active]
929102003363	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
929102003364	triosephosphate isomerase; Provisional; Region: PRK14565
929102003365	substrate binding site [chemical binding]; other site
929102003366	dimer interface [polypeptide binding]; other site
929102003367	catalytic triad [active]
929102003368	Linear amide C-N hydrolases, choloylglycine hydrolase family; Region: CBAH; pfam02275
929102003369	Penicillin V acylase (PVA), also known as conjugated bile salt acid hydrolase (CBAH), catalyzes the hydrolysis of penicillin V to yield 6-amino penicillanic acid (6-APA), an important key intermediate of semisynthetic penicillins.  PVA has an N-terminal...; Region: Ntn_PVA; cd00542
929102003370	active site
929102003371	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
929102003372	ParB-like nuclease domain; Region: ParBc; pfam02195
929102003373	coproporphyrinogen III oxidase; Provisional; Region: PRK08599
929102003374	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
929102003375	FeS/SAM binding site; other site
929102003376	HemN C-terminal domain; Region: HemN_C; pfam06969
929102003377	Lyzozyme M1 (1,4-beta-N-acetylmuramidase) [Cell envelope biogenesis, outer membrane]; Region: Acm; COG3757
929102003378	PlyB is a bacteriophage endolysin that displays potent lytic activity toward Bacillus anthracis.  PlyB has an N-terminal glycosyl hydrolase family 25 (GH25) catalytic domain and a C-terminal bacterial SH3-like domain, SH3b.  Both domains are required for...; Region: GH25_PlyB-like; cd06523
929102003379	active site
929102003380	Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286
929102003381	catalytic motif [active]
929102003382	Zn binding site [ion binding]; other site
929102003383	Acyl-ACP thioesterase [Lipid metabolism]; Region: FatA; COG3884
929102003384	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
929102003385	active site
929102003386	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
929102003387	active site 2 [active]
929102003388	HAD-superfamily subfamily IIA hydrolase, TIGR01457; Region: HAD-SF-IIA-hyp2
929102003389	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
929102003390	active site
929102003391	motif I; other site
929102003392	motif II; other site
929102003393	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
929102003394	Predicted membrane protein [Function unknown]; Region: COG4478
929102003395	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05458
929102003396	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
929102003397	active site
929102003398	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
929102003399	active site
929102003400	xanthine permease; Region: pbuX; TIGR03173
929102003401	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
929102003402	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
929102003403	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
929102003404	folate binding site [chemical binding]; other site
929102003405	NADP+ binding site [chemical binding]; other site
929102003406	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
929102003407	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
929102003408	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929102003409	Walker A motif; other site
929102003410	ATP binding site [chemical binding]; other site
929102003411	Walker B motif; other site
929102003412	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
929102003413	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
929102003414	G1 box; other site
929102003415	GTP/Mg2+ binding site [chemical binding]; other site
929102003416	Switch I region; other site
929102003417	G2 box; other site
929102003418	G3 box; other site
929102003419	Switch II region; other site
929102003420	G4 box; other site
929102003421	G5 box; other site
929102003422	Dihydroneopterin aldolase [Coenzyme metabolism]; Region: FolB; COG1539
929102003423	active site
929102003424	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
929102003425	catalytic center binding site [active]
929102003426	ATP binding site [chemical binding]; other site
929102003427	GTP cyclohydrolase I [Coenzyme metabolism]; Region: FolE; COG0302
929102003428	GTP cyclohydrolase I; Provisional; Region: PLN03044
929102003429	active site
929102003430	dihydropteroate synthase; Region: DHPS; TIGR01496
929102003431	Pterin binding enzymes. This family includes dihydropteroate synthase (DHPS) and cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  DHPS, a...; Region: Pterin_binding; cl00219
929102003432	substrate binding pocket [chemical binding]; other site
929102003433	dimer interface [polypeptide binding]; other site
929102003434	inhibitor binding site; inhibition site
929102003435	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
929102003436	nudix motif; other site
929102003437	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
929102003438	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
929102003439	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
929102003440	Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428
929102003441	Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1; Region: dNK; cd01673
929102003442	Substrate-binding site [chemical binding]; other site
929102003443	Substrate specificity [chemical binding]; other site
929102003444	homoserine dehydrogenase; Provisional; Region: PRK06349
929102003445	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
929102003446	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
929102003447	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
929102003448	homoserine kinase; Provisional; Region: PRK01212
929102003449	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
929102003450	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
929102003451	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
929102003452	FAD binding domain; Region: FAD_binding_4; pfam01565
929102003453	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
929102003454	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
929102003455	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929102003456	Walker A/P-loop; other site
929102003457	ATP binding site [chemical binding]; other site
929102003458	Q-loop/lid; other site
929102003459	ABC transporter signature motif; other site
929102003460	Walker B; other site
929102003461	D-loop; other site
929102003462	H-loop/switch region; other site
929102003463	TOBE domain; Region: TOBE_2; pfam08402
929102003464	ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism]; Region: PotB; COG1176
929102003465	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
929102003466	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
929102003467	dimer interface [polypeptide binding]; other site
929102003468	conserved gate region; other site
929102003469	putative PBP binding loops; other site
929102003470	ABC-ATPase subunit interface; other site
929102003471	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
929102003472	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
929102003473	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
929102003474	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
929102003475	B12 binding site [chemical binding]; other site
929102003476	Radical SAM superfamily; Region: Radical_SAM; pfam04055
929102003477	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
929102003478	Helix-turn-helix domain; Region: HTH_38; pfam13936
929102003479	Integrase core domain; Region: rve; pfam00665
929102003480	H+ Antiporter protein; Region: 2A0121; TIGR00900
929102003481	cardiolipin synthase; Region: bac_cardiolipin; TIGR04265
929102003482	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
929102003483	putative active site [active]
929102003484	catalytic site [active]
929102003485	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
929102003486	putative active site [active]
929102003487	catalytic site [active]
929102003488	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
929102003489	N-acetylmannosamine-6-phosphate 2-epimerase; Provisional; Region: PRK01130
929102003490	putative active site cavity [active]
929102003491	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
929102003492	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
929102003493	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
929102003494	putative active site [active]
929102003495	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
929102003496	TRAM domain; Region: TRAM; cl01282
929102003497	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929102003498	S-adenosylmethionine binding site [chemical binding]; other site
929102003499	Uncharacterized FAD-dependent dehydrogenases [General function prediction only]; Region: COG2509
929102003500	Methyltransferase domain; Region: Methyltransf_31; pfam13847
929102003501	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929102003502	S-adenosylmethionine binding site [chemical binding]; other site
929102003503	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
929102003504	Domain of unknown function DUF20; Region: UPF0118; pfam01594
929102003505	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929102003506	binding surface
929102003507	TPR motif; other site
929102003508	Tetratricopeptide repeat; Region: TPR_12; pfam13424
929102003509	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929102003510	binding surface
929102003511	TPR motif; other site
929102003512	Tetratricopeptide repeat; Region: TPR_12; pfam13424
929102003513	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929102003514	binding surface
929102003515	TPR motif; other site
929102003516	acetolactate synthase; Reviewed; Region: PRK08617
929102003517	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
929102003518	PYR/PP interface [polypeptide binding]; other site
929102003519	dimer interface [polypeptide binding]; other site
929102003520	TPP binding site [chemical binding]; other site
929102003521	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
929102003522	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629
929102003523	TPP-binding site [chemical binding]; other site
929102003524	legume lectins; Region: lectin_L-type; cl14058
929102003525	carbohydrate binding site [chemical binding]; other site
929102003526	metal binding site [ion binding]; metal-binding site
929102003527	Repeat unit of collagen-binding protein domain B; Region: CollagenBindB; cd00222
929102003528	domain interaction interfaces [polypeptide binding]; other site
929102003529	Repeat unit of collagen-binding protein domain B; Region: CollagenBindB; cd00222
929102003530	domain interaction interfaces [polypeptide binding]; other site
929102003531	Repeat unit of collagen-binding protein domain B; Region: CollagenBindB; cd00222
929102003532	domain interaction interfaces [polypeptide binding]; other site
929102003533	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
929102003534	Osmosensitive K+ channel histidine kinase [Signal transduction mechanisms]; Region: KdpD; COG2205
929102003535	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
929102003536	Ligand Binding Site [chemical binding]; other site
929102003537	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
929102003538	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
929102003539	dimer interface [polypeptide binding]; other site
929102003540	phosphorylation site [posttranslational modification]
929102003541	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929102003542	ATP binding site [chemical binding]; other site
929102003543	Mg2+ binding site [ion binding]; other site
929102003544	G-X-G motif; other site
929102003545	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
929102003546	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929102003547	active site
929102003548	phosphorylation site [posttranslational modification]
929102003549	intermolecular recognition site; other site
929102003550	dimerization interface [polypeptide binding]; other site
929102003551	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
929102003552	DNA binding site [nucleotide binding]
929102003553	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
929102003554	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
929102003555	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
929102003556	Soluble P-type ATPase [General function prediction only]; Region: COG4087
929102003557	K+-transporting ATPase, c chain; Region: KdpC; cl00944
929102003558	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
929102003559	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929102003560	non-specific DNA binding site [nucleotide binding]; other site
929102003561	salt bridge; other site
929102003562	sequence-specific DNA binding site [nucleotide binding]; other site
929102003563	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
929102003564	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
929102003565	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
929102003566	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
929102003567	ribonuclease R; Region: RNase_R; TIGR02063
929102003568	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
929102003569	RNB domain; Region: RNB; pfam00773
929102003570	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
929102003571	RNA binding site [nucleotide binding]; other site
929102003572	Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism]; Region: HisC; COG0079
929102003573	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
929102003574	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929102003575	homodimer interface [polypeptide binding]; other site
929102003576	catalytic residue [active]
929102003577	ATP phosphoribosyltransferase, regulatory subunit; Region: hisZ_biosyn_reg; TIGR00443
929102003578	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
929102003579	dimer interface [polypeptide binding]; other site
929102003580	motif 1; other site
929102003581	active site
929102003582	motif 2; other site
929102003583	motif 3; other site
929102003584	ATP phosphoribosyltransferase [Amino acid transport and metabolism]; Region: HisG; COG0040
929102003585	ATP phosphoribosyltransferase catalytic subunit; Reviewed; Region: hisG; PRK01686
929102003586	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
929102003587	histidinol dehydrogenase; Region: hisD; TIGR00069
929102003588	NAD binding site [chemical binding]; other site
929102003589	dimerization interface [polypeptide binding]; other site
929102003590	product binding site; other site
929102003591	substrate binding site [chemical binding]; other site
929102003592	zinc binding site [ion binding]; other site
929102003593	catalytic residues [active]
929102003594	Methyltransferase domain; Region: Methyltransf_23; pfam13489
929102003595	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
929102003596	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
929102003597	putative active site pocket [active]
929102003598	4-fold oligomerization interface [polypeptide binding]; other site
929102003599	metal binding residues [ion binding]; metal-binding site
929102003600	3-fold/trimer interface [polypeptide binding]; other site
929102003601	Aminoglycoside 3'-phosphotransferase (APH). The APH subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin...; Region: APH; cd05150
929102003602	active site
929102003603	ATP binding site [chemical binding]; other site
929102003604	Phosphotransferase enzyme family; Region: APH; pfam01636
929102003605	antibiotic binding site [chemical binding]; other site
929102003606	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13141
929102003607	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
929102003608	putative active site [active]
929102003609	oxyanion strand; other site
929102003610	catalytic triad [active]
929102003611	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
929102003612	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
929102003613	catalytic residues [active]
929102003614	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
929102003615	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
929102003616	substrate binding site [chemical binding]; other site
929102003617	glutamase interaction surface [polypeptide binding]; other site
929102003618	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
929102003619	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
929102003620	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
929102003621	metal binding site [ion binding]; metal-binding site
929102003622	histidinol phosphate phosphatase, HisJ family; Region: hisJ_fam; TIGR01856
929102003623	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
929102003624	active site
929102003625	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
929102003626	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
929102003627	active site residue [active]
929102003628	Protein of unknown function (DUF3650); Region: DUF3650; pfam12368
929102003629	2-isopropylmalate synthase; Validated; Region: PRK00915
929102003630	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
929102003631	active site
929102003632	catalytic residues [active]
929102003633	metal binding site [ion binding]; metal-binding site
929102003634	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
929102003635	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
929102003636	tartrate dehydrogenase; Region: TTC; TIGR02089
929102003637	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
929102003638	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
929102003639	substrate binding site [chemical binding]; other site
929102003640	ligand binding site [chemical binding]; other site
929102003641	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
929102003642	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
929102003643	substrate binding site [chemical binding]; other site
929102003644	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929102003645	ABC transporter; Region: ABC_tran; pfam00005
929102003646	Q-loop/lid; other site
929102003647	ABC transporter signature motif; other site
929102003648	Walker B; other site
929102003649	D-loop; other site
929102003650	H-loop/switch region; other site
929102003651	dihydroxy-acid dehydratase; Provisional; Region: PRK00911
929102003652	acetolactate synthase catalytic subunit; Reviewed; Region: PRK07282
929102003653	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
929102003654	PYR/PP interface [polypeptide binding]; other site
929102003655	dimer interface [polypeptide binding]; other site
929102003656	TPP binding site [chemical binding]; other site
929102003657	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
929102003658	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
929102003659	TPP-binding site [chemical binding]; other site
929102003660	dimer interface [polypeptide binding]; other site
929102003661	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
929102003662	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
929102003663	putative valine binding site [chemical binding]; other site
929102003664	dimer interface [polypeptide binding]; other site
929102003665	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
929102003666	ketol-acid reductoisomerase; Provisional; Region: PRK05479
929102003667	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
929102003668	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
929102003669	threonine dehydratase; Validated; Region: PRK08639
929102003670	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
929102003671	tetramer interface [polypeptide binding]; other site
929102003672	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929102003673	catalytic residue [active]
929102003674	C-terminal regulatory domain of Threonine dehydratase; Region: Thr_dehydrat_C; pfam00585
929102003675	alpha-acetolactate decarboxylase; Region: acetolac_decarb; TIGR01252
929102003676	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
929102003677	homotrimer interaction site [polypeptide binding]; other site
929102003678	putative active site [active]
929102003679	DNA topoisomerase I; Validated; Region: PRK05582
929102003680	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
929102003681	active site
929102003682	interdomain interaction site; other site
929102003683	putative metal-binding site [ion binding]; other site
929102003684	nucleotide binding site [chemical binding]; other site
929102003685	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
929102003686	domain I; other site
929102003687	DNA binding groove [nucleotide binding]
929102003688	phosphate binding site [ion binding]; other site
929102003689	domain II; other site
929102003690	domain III; other site
929102003691	nucleotide binding site [chemical binding]; other site
929102003692	catalytic site [active]
929102003693	domain IV; other site
929102003694	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
929102003695	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
929102003696	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
929102003697	Glucose inhibited division protein A; Region: GIDA; pfam01134
929102003698	site-specific tyrosine recombinase XerS; Reviewed; Region: xerS; PRK05084
929102003699	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
929102003700	active site
929102003701	DNA binding site [nucleotide binding]
929102003702	Int/Topo IB signature motif; other site
929102003703	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
929102003704	Predicted acyl esterases [General function prediction only]; Region: COG2936
929102003705	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; pfam08530
929102003706	Transcriptional regulator [Transcription]; Region: LysR; COG0583
929102003707	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
929102003708	LysR substrate binding domain; Region: LysR_substrate; pfam03466
929102003709	dimerization interface [polypeptide binding]; other site
929102003710	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
929102003711	N(5)-(carboxyethyl)ornithine synthase; Region: ceo_syn; cd12181
929102003712	putative active site [active]
929102003713	putative ligand binding site [chemical binding]; other site
929102003714	putative NAD(P) binding site [chemical binding]; other site
929102003715	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1302
929102003716	Small integral membrane protein [Function unknown]; Region: COG5547
929102003717	UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell envelope biogenesis, outer membrane]; Region: MurD; COG0771
929102003718	Predicted membrane protein [Function unknown]; Region: COG2261
929102003719	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
929102003720	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
929102003721	active site
929102003722	catalytic tetrad [active]
929102003723	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
929102003724	amphipathic channel; other site
929102003725	Asn-Pro-Ala signature motifs; other site
929102003726	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GlpA; COG0578
929102003727	glycerol kinase; Provisional; Region: glpK; PRK00047
929102003728	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
929102003729	N- and C-terminal domain interface [polypeptide binding]; other site
929102003730	active site
929102003731	MgATP binding site [chemical binding]; other site
929102003732	catalytic site [active]
929102003733	metal binding site [ion binding]; metal-binding site
929102003734	glycerol binding site [chemical binding]; other site
929102003735	homotetramer interface [polypeptide binding]; other site
929102003736	homodimer interface [polypeptide binding]; other site
929102003737	FBP binding site [chemical binding]; other site
929102003738	protein IIAGlc interface [polypeptide binding]; other site
929102003739	Mga helix-turn-helix domain; Region: Mga; pfam05043
929102003740	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
929102003741	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
929102003742	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
929102003743	active site
929102003744	Na/Ca binding site [ion binding]; other site
929102003745	catalytic site [active]
929102003746	L-lactate oxidase; Region: L_lactate_ox; TIGR02708
929102003747	L-Lactate oxidase (LOX) FMN-binding domain. LOX is a member of the family of FMN-containing alpha-hydroxyacid oxidases and catalyzes the oxidation of l-lactate using molecular oxygen to generate pyruvate and H2O2.  This family occurs in both prokaryotes...; Region: LOX_like_FMN; cd04737
929102003748	teramer interface [polypeptide binding]; other site
929102003749	active site
929102003750	FMN binding site [chemical binding]; other site
929102003751	catalytic residues [active]
929102003752	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase [Amino acid transport and metabolism]; Region: AroG; COG0722
929102003753	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
929102003754	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
929102003755	FAD binding site [chemical binding]; other site
929102003756	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
929102003757	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
929102003758	THF binding site; other site
929102003759	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
929102003760	substrate binding site [chemical binding]; other site
929102003761	THF binding site; other site
929102003762	zinc-binding site [ion binding]; other site
929102003763	Mn-dependent transcriptional regulator [Transcription]; Region: TroR; COG1321
929102003764	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
929102003765	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
929102003766	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
929102003767	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
929102003768	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
929102003769	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
929102003770	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
929102003771	Soluble P-type ATPase [General function prediction only]; Region: COG4087
929102003772	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
929102003773	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) [Cell envelope biogenesis, outer membrane]; Region: DltD; COG3966
929102003774	DltD N-terminal region; Region: DltD_N; pfam04915
929102003775	DltD central region; Region: DltD_M; pfam04918
929102003776	DltD C-terminal region; Region: DltD_C; pfam04914
929102003777	D-alanine--poly(phosphoribitol) ligase subunit 2; Validated; Region: PRK05087
929102003778	D-alanyl-lipoteichoic acid biosynthesis protein DltB; Region: LTA_dltB; TIGR04091
929102003779	D-alanine--poly(phosphoribitol) ligase, subunit 1; Region: D-ala-DACP-lig; TIGR01734
929102003780	D-alanine:D-alanyl carrier protein ligase (DltA); Region: DltA; cd05945
929102003781	acyl-activating enzyme (AAE) consensus motif; other site
929102003782	AMP binding site [chemical binding]; other site
929102003783	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
929102003784	thiamine phosphate binding site [chemical binding]; other site
929102003785	active site
929102003786	pyrophosphate binding site [ion binding]; other site
929102003787	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
929102003788	substrate binding site [chemical binding]; other site
929102003789	dimer interface [polypeptide binding]; other site
929102003790	ATP binding site [chemical binding]; other site
929102003791	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
929102003792	substrate binding site [chemical binding]; other site
929102003793	multimerization interface [polypeptide binding]; other site
929102003794	ATP binding site [chemical binding]; other site
929102003795	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
929102003796	N-acetyl-glucosamine transferase is involved in the synthesis of Poly-beta-1,6-N-acetyl-D-glucosamine; Region: GlcNAc-1-P_transferase; cd06436
929102003797	DXD motif; other site
929102003798	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
929102003799	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
929102003800	active site
929102003801	homodimer interface [polypeptide binding]; other site
929102003802	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
929102003803	core dimer interface [polypeptide binding]; other site
929102003804	peripheral dimer interface [polypeptide binding]; other site
929102003805	L10 interface [polypeptide binding]; other site
929102003806	L11 interface [polypeptide binding]; other site
929102003807	putative EF-Tu interaction site [polypeptide binding]; other site
929102003808	putative EF-G interaction site [polypeptide binding]; other site
929102003809	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
929102003810	23S rRNA interface [nucleotide binding]; other site
929102003811	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
929102003812	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
929102003813	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929102003814	non-specific DNA binding site [nucleotide binding]; other site
929102003815	salt bridge; other site
929102003816	sequence-specific DNA binding site [nucleotide binding]; other site
929102003817	Predicted transcriptional regulator [Transcription]; Region: COG2932
929102003818	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
929102003819	Catalytic site [active]
929102003820	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
929102003821	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
929102003822	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
929102003823	Walker A/P-loop; other site
929102003824	ATP binding site [chemical binding]; other site
929102003825	Q-loop/lid; other site
929102003826	ABC transporter signature motif; other site
929102003827	Walker B; other site
929102003828	D-loop; other site
929102003829	H-loop/switch region; other site
929102003830	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
929102003831	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
929102003832	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929102003833	Walker A/P-loop; other site
929102003834	ATP binding site [chemical binding]; other site
929102003835	Q-loop/lid; other site
929102003836	ABC transporter signature motif; other site
929102003837	Walker B; other site
929102003838	D-loop; other site
929102003839	H-loop/switch region; other site
929102003840	Predicted membrane protein [Function unknown]; Region: COG3601
929102003841	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
929102003842	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
929102003843	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
929102003844	RNA binding surface [nucleotide binding]; other site
929102003845	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
929102003846	active site
929102003847	segregation and condensation protein B; Reviewed; Region: scpB; PRK00135
929102003848	segregation and condensation protein A; Reviewed; Region: scpA; PRK00104
929102003849	site-specific tyrosine recombinase XerD-like protein; Reviewed; Region: xerD; PRK02436
929102003850	Phage integrase, N-terminal SAM-like domain; Region: Phage_integr_N2; pfam13495
929102003851	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
929102003852	DNA binding site [nucleotide binding]
929102003853	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
929102003854	active site
929102003855	metal binding site [ion binding]; metal-binding site
929102003856	homotetramer interface [polypeptide binding]; other site
929102003857	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
929102003858	active site
929102003859	dimerization interface [polypeptide binding]; other site
929102003860	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3763
929102003861	Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019
929102003862	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
929102003863	active site
929102003864	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
929102003865	substrate binding site [chemical binding]; other site
929102003866	catalytic residues [active]
929102003867	dimer interface [polypeptide binding]; other site
929102003868	glutamate synthase subunit beta; Reviewed; Region: gltD; PRK12810
929102003869	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
929102003870	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
929102003871	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
929102003872	active site
929102003873	dimer interface [polypeptide binding]; other site
929102003874	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
929102003875	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
929102003876	active site
929102003877	FMN binding site [chemical binding]; other site
929102003878	substrate binding site [chemical binding]; other site
929102003879	3Fe-4S cluster binding site [ion binding]; other site
929102003880	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
929102003881	domain interface; other site
929102003882	galactoside O-acetyltransferase; Reviewed; Region: lacA; PRK09527
929102003883	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
929102003884	active site
929102003885	substrate binding site [chemical binding]; other site
929102003886	trimer interface [polypeptide binding]; other site
929102003887	CoA binding site [chemical binding]; other site
929102003888	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
929102003889	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
929102003890	homodimer interface [polypeptide binding]; other site
929102003891	substrate-cofactor binding pocket; other site
929102003892	catalytic residue [active]
929102003893	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
929102003894	Mechanosensitive ion channel; Region: MS_channel; pfam00924
929102003895	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
929102003896	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929102003897	catalytic residue [active]
929102003898	glutamate:gamma-aminobutyrate antiporter; Region: 2A0307_GadC; TIGR00910
929102003899	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929102003900	non-specific DNA binding site [nucleotide binding]; other site
929102003901	salt bridge; other site
929102003902	sequence-specific DNA binding site [nucleotide binding]; other site
929102003903	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
929102003904	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
929102003905	RNA/DNA hybrid binding site [nucleotide binding]; other site
929102003906	active site
929102003907	GTPase YlqF; Reviewed; Region: rbgA; PRK09563
929102003908	Circularly permuted YlqF GTPase; Region: YlqF; cd01856
929102003909	GTP/Mg2+ binding site [chemical binding]; other site
929102003910	G4 box; other site
929102003911	G5 box; other site
929102003912	G1 box; other site
929102003913	Switch I region; other site
929102003914	G2 box; other site
929102003915	G3 box; other site
929102003916	Switch II region; other site
929102003917	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
929102003918	Coenzyme A binding pocket [chemical binding]; other site
929102003919	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
929102003920	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
929102003921	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
929102003922	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
929102003923	Predicted membrane protein [Function unknown]; Region: COG3152
929102003924	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
929102003925	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
929102003926	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
929102003927	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
929102003928	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
929102003929	Predicted periplasmic or secreted protein [General function prediction only]; Region: COG3443
929102003930	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
929102003931	Helix-turn-helix domain; Region: HTH_38; pfam13936
929102003932	Integrase core domain; Region: rve; pfam00665
929102003933	Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes [Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only]; Region: COG3961
929102003934	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
929102003935	dimer interface [polypeptide binding]; other site
929102003936	PYR/PP interface [polypeptide binding]; other site
929102003937	TPP binding site [chemical binding]; other site
929102003938	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
929102003939	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629
929102003940	TPP-binding site [chemical binding]; other site
929102003941	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
929102003942	MarR family; Region: MarR_2; pfam12802
929102003943	Transcriptional regulator [Transcription]; Region: LysR; COG0583
929102003944	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
929102003945	Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657
929102003946	YbaB/EbfC DNA-binding family; Region: YbaB_DNA_bd; cl00494
929102003947	short chain dehydrogenase; Validated; Region: PRK06182
929102003948	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
929102003949	NADP binding site [chemical binding]; other site
929102003950	active site
929102003951	steroid binding site; other site
929102003952	Arabinose-binding domain of AraC transcription regulator, N-term; Region: Arabinose_bd; pfam12625
929102003953	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
929102003954	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929102003955	Protein of unknown function (DUF1706); Region: DUF1706; pfam08020
929102003956	Arsenical resistance operon trans-acting repressor ArsD; Region: ArsD; pfam06953
929102003957	Arsenate reductase and related proteins, glutaredoxin family [Inorganic ion transport and metabolism]; Region: ArsC; COG1393
929102003958	ArsC family; Region: ArsC; pfam03960
929102003959	Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism]; Region: TrpE; COG0147
929102003960	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
929102003961	aminodeoxychorismate synthase, component I, bacterial clade; Region: pabB; TIGR00553
929102003962	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
929102003963	substrate-cofactor binding pocket; other site
929102003964	homodimer interface [polypeptide binding]; other site
929102003965	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cl00224
929102003966	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929102003967	catalytic residue [active]
929102003968	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
929102003969	Glutamine amidotransferase class-I; Region: GATase; pfam00117
929102003970	glutamine binding [chemical binding]; other site
929102003971	catalytic triad [active]
929102003972	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
929102003973	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
929102003974	metal binding site [ion binding]; metal-binding site
929102003975	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
929102003976	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
929102003977	ABC-ATPase subunit  interface; other site
929102003978	dimer interface [polypeptide binding]; other site
929102003979	putative PBP binding regions; other site
929102003980	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
929102003981	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
929102003982	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_24; cd09012
929102003983	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4495
929102003984	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: SbcC; COG0419
929102003985	ATP-binding cassette domain of sbcCD; Region: ABC_sbcCD; cd03279
929102003986	Walker A/P-loop; other site
929102003987	ATP binding site [chemical binding]; other site
929102003988	Q-loop/lid; other site
929102003989	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929102003990	ABC transporter signature motif; other site
929102003991	Walker B; other site
929102003992	D-loop; other site
929102003993	H-loop/switch region; other site
929102003994	DNA repair exonuclease [DNA replication, recombination, and repair]; Region: SbcD; COG0420
929102003995	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
929102003996	active site
929102003997	metal binding site [ion binding]; metal-binding site
929102003998	DNA binding site [nucleotide binding]
929102003999	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
929102004000	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
929102004001	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
929102004002	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
929102004003	Arsenate Reductase (ArsC) family, Spx subfamily; Spx is a unique RNA polymerase (RNAP)-binding protein present in bacilli and some mollicutes. It inhibits transcription by binding to the C-terminal domain of the alpha subunit of RNAP, disrupting complex...; Region: ArsC_Spx; cd03032
929102004004	ArsC family; Region: ArsC; pfam03960
929102004005	putative catalytic residues [active]
929102004006	thiol/disulfide switch; other site
929102004007	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
929102004008	Protein of unknown function (DUF3592); Region: DUF3592; pfam12158
929102004009	Predicted RNA-binding protein homologous to eukaryotic snRNP [Transcription]; Region: COG1293
929102004010	Domain of unknown function (DUF814); Region: DUF814; pfam05670
929102004011	ABC-type uncharacterized transport systems, ATPase components [General function prediction only]; Region: COG3845
929102004012	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
929102004013	Walker A/P-loop; other site
929102004014	ATP binding site [chemical binding]; other site
929102004015	Q-loop/lid; other site
929102004016	ABC transporter signature motif; other site
929102004017	Walker B; other site
929102004018	D-loop; other site
929102004019	H-loop/switch region; other site
929102004020	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
929102004021	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
929102004022	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
929102004023	TM-ABC transporter signature motif; other site
929102004024	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
929102004025	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
929102004026	TM-ABC transporter signature motif; other site
929102004027	L-lactate dehydrogenase; Reviewed; Region: ldh; PRK00066
929102004028	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
929102004029	tetramer (dimer of dimers) interface [polypeptide binding]; other site
929102004030	NAD binding site [chemical binding]; other site
929102004031	dimer interface [polypeptide binding]; other site
929102004032	substrate binding site [chemical binding]; other site
929102004033	pyruvate kinase; Provisional; Region: PRK05826
929102004034	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
929102004035	domain interfaces; other site
929102004036	active site
929102004037	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
929102004038	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
929102004039	active site
929102004040	ADP/pyrophosphate binding site [chemical binding]; other site
929102004041	dimerization interface [polypeptide binding]; other site
929102004042	allosteric effector site; other site
929102004043	fructose-1,6-bisphosphate binding site; other site
929102004044	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
929102004045	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
929102004046	active site
929102004047	dimer interface [polypeptide binding]; other site
929102004048	Uncharacterized protein involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TelA; COG3853
929102004049	5-bromo-4-chloroindolyl phosphate hydrolysis protein [General function prediction only]; Region: XpaC; COG4915
929102004050	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
929102004051	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
929102004052	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
929102004053	glucose-1-phosphate thymidylyltransferase RfbA; Provisional; Region: PRK15480
929102004054	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
929102004055	active site
929102004056	tetramer interface; other site
929102004057	Listerrria innocua Lin0431  is similar to the N-Utilization Substance G (NusG) N terminal (NGN) insert (DII); Region: Lin0431_like; cd09911
929102004058	trimer interface [polypeptide binding]; other site
929102004059	Predicted membrane protein [Function unknown]; Region: COG4769
929102004060	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
929102004061	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
929102004062	substrate binding pocket [chemical binding]; other site
929102004063	chain length determination region; other site
929102004064	substrate-Mg2+ binding site; other site
929102004065	catalytic residues [active]
929102004066	aspartate-rich region 1; other site
929102004067	active site lid residues [active]
929102004068	aspartate-rich region 2; other site
929102004069	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
929102004070	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929102004071	S-adenosylmethionine binding site [chemical binding]; other site
929102004072	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
929102004073	active site
929102004074	dimer interface [polypeptide binding]; other site
929102004075	dihydroorotate dehydrogenase (subfamily 1) family protein; Region: pyrD_sub1_fam; TIGR01037
929102004076	Dihydroorotate dehydrogenase (DHOD) class 1B FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine...; Region: DHOD_1B_like; cd04740
929102004077	heterodimer interface [polypeptide binding]; other site
929102004078	active site
929102004079	FMN binding site [chemical binding]; other site
929102004080	homodimer interface [polypeptide binding]; other site
929102004081	substrate binding site [chemical binding]; other site
929102004082	dihydroorotate dehydrogenase electron transfer subunit; Reviewed; Region: PRK00054
929102004083	FAD/NAD binding domain in the electron transfer subunit of dihydroorotate dehydrogenase. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)-dihydroorotate to...; Region: DHOD_e_trans; cd06218
929102004084	FAD binding pocket [chemical binding]; other site
929102004085	FAD binding motif [chemical binding]; other site
929102004086	phosphate binding motif [ion binding]; other site
929102004087	beta-alpha-beta structure motif; other site
929102004088	NAD binding pocket [chemical binding]; other site
929102004089	Iron coordination center [ion binding]; other site
929102004090	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929102004091	Major Facilitator Superfamily; Region: MFS_1; pfam07690
929102004092	putative substrate translocation pore; other site
929102004093	Membrane protease subunit, stomatin/prohibitin family [Amino acid    transport and metabolism]; Region: COG4260
929102004094	A subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual...; Region: Band_7_5; cd03408
929102004095	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
929102004096	Protein of unknown function (DUF1407); Region: DUF1407; pfam07191
929102004097	Beta-propeller domains of methanol dehydrogenase type [General function prediction only]; Region: COG1512
929102004098	Repair protein; Region: Repair_PSII; pfam04536
929102004099	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
929102004100	pseudouridine synthase; Region: TIGR00093
929102004101	active site
929102004102	WxL domain surface cell wall-binding; Region: WxL; pfam13731
929102004103	Bacterial protein of unknown function (DUF916); Region: DUF916; pfam06030
929102004104	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
929102004105	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
929102004106	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
929102004107	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
929102004108	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
929102004109	ATP-grasp domain; Region: ATP-grasp_4; cl17255
929102004110	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
929102004111	IMP binding site; other site
929102004112	dimer interface [polypeptide binding]; other site
929102004113	interdomain contacts; other site
929102004114	partial ornithine binding site; other site
929102004115	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
929102004116	catalytic residues [active]
929102004117	dimer interface [polypeptide binding]; other site
929102004118	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
929102004119	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
929102004120	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
929102004121	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
929102004122	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
929102004123	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
929102004124	motif II; other site
929102004125	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
929102004126	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1636
929102004127	Protein of unknown function (DUF1211); Region: DUF1211; cl01421
929102004128	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
929102004129	Helix-turn-helix domain; Region: HTH_38; pfam13936
929102004130	Integrase core domain; Region: rve; pfam00665
929102004131	TraX protein; Region: TraX; cl05434
929102004132	Protein of unknown function (DUF1304); Region: DUF1304; pfam06993
929102004133	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
929102004134	Ligand Binding Site [chemical binding]; other site
929102004135	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
929102004136	Low molecular weight phosphatase family; Region: LMWPc; cd00115
929102004137	active site
929102004138	putative DNA-binding protein; Validated; Region: PRK00118
929102004139	Putative helix-turn-helix protein, YlxM / p13 like; Region: UPF0122; pfam04297
929102004140	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
929102004141	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929102004142	active site
929102004143	phosphorylation site [posttranslational modification]
929102004144	intermolecular recognition site; other site
929102004145	dimerization interface [polypeptide binding]; other site
929102004146	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
929102004147	DNA binding site [nucleotide binding]
929102004148	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
929102004149	dimer interface [polypeptide binding]; other site
929102004150	phosphorylation site [posttranslational modification]
929102004151	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929102004152	ATP binding site [chemical binding]; other site
929102004153	Mg2+ binding site [ion binding]; other site
929102004154	G-X-G motif; other site
929102004155	Domain of unknown function (DUF4395); Region: DUF4395; pfam14340
929102004156	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
929102004157	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
929102004158	DNA-binding site [nucleotide binding]; DNA binding site
929102004159	UTRA domain; Region: UTRA; pfam07702
929102004160	Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein [General function prediction only]; Region: Med; COG1744
929102004161	Periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea; Region: PBP1_BmpA_PnrA_like; cd06354
929102004162	ligand binding site [chemical binding]; other site
929102004163	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
929102004164	active site
929102004165	catalytic motif [active]
929102004166	Zn binding site [ion binding]; other site
929102004167	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
929102004168	intersubunit interface [polypeptide binding]; other site
929102004169	active site
929102004170	catalytic residue [active]
929102004171	pyrimidine-nucleoside phosphorylase; Reviewed; Region: PRK06078
929102004172	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
929102004173	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
929102004174	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
929102004175	Methyltransferase domain; Region: Methyltransf_31; pfam13847
929102004176	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929102004177	S-adenosylmethionine binding site [chemical binding]; other site
929102004178	pantothenate kinase; Provisional; Region: PRK05439
929102004179	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
929102004180	ATP-binding site [chemical binding]; other site
929102004181	CoA-binding site [chemical binding]; other site
929102004182	Mg2+-binding site [ion binding]; other site
929102004183	Phosphate-starvation-inducible E; Region: PsiE; cl01264
929102004184	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
929102004185	Cation efflux family; Region: Cation_efflux; pfam01545
929102004186	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929102004187	non-specific DNA binding site [nucleotide binding]; other site
929102004188	salt bridge; other site
929102004189	sequence-specific DNA binding site [nucleotide binding]; other site
929102004190	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
929102004191	ParB-like nuclease domain; Region: ParBc; pfam02195
929102004192	Transcriptional regulator C-terminal region; Region: TetR_C_8; pfam14278
929102004193	Protein of unknown function (DUF3042); Region: DUF3042; pfam11240
929102004194	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
929102004195	dimer interface [polypeptide binding]; other site
929102004196	conserved gate region; other site
929102004197	putative PBP binding loops; other site
929102004198	ABC-ATPase subunit interface; other site
929102004199	ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; COG2113
929102004200	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
929102004201	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
929102004202	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
929102004203	DNA-binding site [nucleotide binding]; DNA binding site
929102004204	Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels [Inorganic ion transport and metabolism]; Region: COG0490
929102004205	TrkA-C domain; Region: TrkA_C; pfam02080
929102004206	This family is most closely related to the GT1 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding.  In...; Region: GT1_gtfA_like; cd04949
929102004207	KxYKxGKxW signal peptide; Region: KxYKxGKxW; TIGR03715
929102004208	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
929102004209	beta-galactosidase; Region: BGL; TIGR03356
929102004210	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
929102004211	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
929102004212	active site turn [active]
929102004213	phosphorylation site [posttranslational modification]
929102004214	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
929102004215	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
929102004216	HPr interaction site; other site
929102004217	glycerol kinase (GK) interaction site [polypeptide binding]; other site
929102004218	active site
929102004219	phosphorylation site [posttranslational modification]
929102004220	transcriptional antiterminator BglG; Provisional; Region: PRK09772
929102004221	CAT RNA binding domain; Region: CAT_RBD; pfam03123
929102004222	PRD domain; Region: PRD; pfam00874
929102004223	PRD domain; Region: PRD; pfam00874
929102004224	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
929102004225	substrate binding site [chemical binding]; other site
929102004226	active site
929102004227	catalytic residues [active]
929102004228	heterodimer interface [polypeptide binding]; other site
929102004229	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
929102004230	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
929102004231	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929102004232	catalytic residue [active]
929102004233	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
929102004234	active site
929102004235	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
929102004236	active site
929102004237	ribulose/triose binding site [chemical binding]; other site
929102004238	phosphate binding site [ion binding]; other site
929102004239	substrate (anthranilate) binding pocket [chemical binding]; other site
929102004240	product (indole) binding pocket [chemical binding]; other site
929102004241	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
929102004242	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
929102004243	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
929102004244	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
929102004245	Glutamine amidotransferase class-I; Region: GATase; pfam00117
929102004246	glutamine binding [chemical binding]; other site
929102004247	catalytic triad [active]
929102004248	anthranilate synthase component I; Provisional; Region: PRK13570
929102004249	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
929102004250	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
929102004251	Predicted membrane protein [Function unknown]; Region: COG3759
929102004252	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929102004253	S-adenosylmethionine binding site [chemical binding]; other site
929102004254	Nodulin-21 and CCC1-related protein family; Region: Nodulin-21_like_1; cd02432
929102004255	Nodulin-21 and CCC1-related protein family; Region: Nodulin-21_like_1; cd02432
929102004256	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
929102004257	metal binding site 2 [ion binding]; metal-binding site
929102004258	putative DNA binding helix; other site
929102004259	metal binding site 1 [ion binding]; metal-binding site
929102004260	dimer interface [polypeptide binding]; other site
929102004261	structural Zn2+ binding site [ion binding]; other site
929102004262	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5294
929102004263	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
929102004264	EamA-like transporter family; Region: EamA; pfam00892
929102004265	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
929102004266	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
929102004267	DNA binding residues [nucleotide binding]
929102004268	putative dimer interface [polypeptide binding]; other site
929102004269	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
929102004270	classical (c) SDRs; Region: SDR_c; cd05233
929102004271	NAD(P) binding site [chemical binding]; other site
929102004272	active site
929102004273	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK12315
929102004274	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
929102004275	TPP-binding site; other site
929102004276	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
929102004277	PYR/PP interface [polypeptide binding]; other site
929102004278	dimer interface [polypeptide binding]; other site
929102004279	TPP binding site [chemical binding]; other site
929102004280	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
929102004281	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
929102004282	MarR family; Region: MarR; pfam01047
929102004283	uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u2; cd12827
929102004284	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
929102004285	Cl binding site [ion binding]; other site
929102004286	oligomer interface [polypeptide binding]; other site
929102004287	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
929102004288	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
929102004289	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
929102004290	GMP synthase; Reviewed; Region: guaA; PRK00074
929102004291	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
929102004292	AMP/PPi binding site [chemical binding]; other site
929102004293	candidate oxyanion hole; other site
929102004294	catalytic triad [active]
929102004295	potential glutamine specificity residues [chemical binding]; other site
929102004296	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
929102004297	ATP Binding subdomain [chemical binding]; other site
929102004298	Dimerization subdomain; other site
929102004299	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
929102004300	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
929102004301	nucleotide binding site [chemical binding]; other site
929102004302	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
929102004303	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
929102004304	nucleotide binding site [chemical binding]; other site
929102004305	butyrate kinase; Provisional; Region: PRK03011
929102004306	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
929102004307	beta-galactosidase; Region: BGL; TIGR03356
929102004308	Predicted integral membrane protein [Function unknown]; Region: COG5578
929102004309	Endo-beta-N-acetylglucosaminidase D [Carbohydrate transport and metabolism]; Region: COG4724
929102004310	Endo-beta-N-acetylglucosaminidase (ENGase) hydrolyzes the N-N'-diacetylchitobiosyl core of N-glycosylproteins.  The beta-1,4-glycosyl bond located between two N-acetylglucosamine residues is hydrolyzed such that N-acetylglucosamine 1 remains with...; Region: GH85_ENGase; cd06547
929102004311	putative active site [active]
929102004312	FOG: PKD repeat [General function prediction only]; Region: COG3291
929102004313	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
929102004314	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
929102004315	sugar binding site [chemical binding]; other site
929102004316	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
929102004317	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
929102004318	Ca binding site [ion binding]; other site
929102004319	active site
929102004320	catalytic site [active]
929102004321	Glycosyl hydrolase family 20 (GH20) catalytic domain of dispersin B (DspB), lacto-N-biosidase (LnbB) and related proteins. Dispersin B is a soluble beta-N-acetylglucosamidase found in bacteria that hydrolyzes the beta-1,6-linkages of PGA (poly-beta-(1,6)...; Region: GH20_DspB_LnbB-like; cd06564
929102004322	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
929102004323	active site
929102004324	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
929102004325	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
929102004326	Domain of unknown function (DUF3502); Region: DUF3502; pfam12010
929102004327	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
929102004328	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
929102004329	dimer interface [polypeptide binding]; other site
929102004330	conserved gate region; other site
929102004331	putative PBP binding loops; other site
929102004332	ABC-ATPase subunit interface; other site
929102004333	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
929102004334	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
929102004335	dimer interface [polypeptide binding]; other site
929102004336	conserved gate region; other site
929102004337	putative PBP binding loops; other site
929102004338	ABC-ATPase subunit interface; other site
929102004339	Alpha-mannosidase [Carbohydrate transport and metabolism]; Region: AMS1; COG0383
929102004340	N-terminal catalytic domain of SPGH38, a putative alpha-mannosidase of Streptococcus pyogenes, and its prokaryotic homologs; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_SpGH38_like; cd10814
929102004341	active site
929102004342	metal binding site [ion binding]; metal-binding site
929102004343	homodimer interface [polypeptide binding]; other site
929102004344	catalytic site [active]
929102004345	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; smart00872
929102004346	Uncharacterized conserved protein [Function unknown]; Region: COG3538
929102004347	Protein of unknown function (DUF1237); Region: DUF1237; pfam06824
929102004348	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
929102004349	DNA-binding site [nucleotide binding]; DNA binding site
929102004350	Transcriptional regulators [Transcription]; Region: PurR; COG1609
929102004351	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
929102004352	ligand binding site [chemical binding]; other site
929102004353	dimerization interface [polypeptide binding]; other site
929102004354	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
929102004355	Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971
929102004356	putative phosphoketolase; Provisional; Region: PRK05261
929102004357	XFP N-terminal domain; Region: XFP_N; pfam09364
929102004358	XFP C-terminal domain; Region: XFP_C; pfam09363
929102004359	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
929102004360	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929102004361	putative substrate translocation pore; other site
929102004362	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929102004363	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
929102004364	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
929102004365	active site
929102004366	substrate binding site [chemical binding]; other site
929102004367	trimer interface [polypeptide binding]; other site
929102004368	CoA binding site [chemical binding]; other site
929102004369	Beta-xylosidase [Carbohydrate transport and metabolism]; Region: XynB; COG3507
929102004370	Glycosyl hydrolase family 43, beta-D-xylosidase; Region: GH43_XYL_1; cd09000
929102004371	inhibitor binding site; inhibition site
929102004372	active site
929102004373	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
929102004374	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
929102004375	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
929102004376	active site
929102004377	catalytic residues [active]
929102004378	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
929102004379	N- and C-terminal domain interface [polypeptide binding]; other site
929102004380	D-xylulose kinase; Region: XylB; TIGR01312
929102004381	active site
929102004382	MgATP binding site [chemical binding]; other site
929102004383	catalytic site [active]
929102004384	metal binding site [ion binding]; metal-binding site
929102004385	xylulose binding site [chemical binding]; other site
929102004386	homodimer interface [polypeptide binding]; other site
929102004387	Cupin domain; Region: Cupin_2; pfam07883
929102004388	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929102004389	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
929102004390	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929102004391	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
929102004392	ATP-grasp domain; Region: ATP-grasp; pfam02222
929102004393	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
929102004394	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
929102004395	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
929102004396	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
929102004397	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
929102004398	tetracycline repressor protein TetR; Provisional; Region: PRK13756
929102004399	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
929102004400	Tetracyclin repressor, C-terminal all-alpha domain; Region: TetR_C; pfam02909
929102004401	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929102004402	Major Facilitator Superfamily; Region: MFS_1; pfam07690
929102004403	putative substrate translocation pore; other site
929102004404	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929102004405	HAD superfamily (subfamily IA) hydrolase, TIGR02254; Region: YjjG/YfnB
929102004406	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
929102004407	motif II; other site
929102004408	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
929102004409	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
929102004410	purine monophosphate binding site [chemical binding]; other site
929102004411	dimer interface [polypeptide binding]; other site
929102004412	putative catalytic residues [active]
929102004413	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
929102004414	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
929102004415	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
929102004416	active site
929102004417	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
929102004418	aldehyde reductase, extended (e) SDRs; Region: AR_SDR_e; cd05227
929102004419	NADP binding site [chemical binding]; other site
929102004420	putative substrate binding site [chemical binding]; other site
929102004421	active site
929102004422	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
929102004423	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
929102004424	Folate-dependent phosphoribosylglycinamide formyltransferase PurN [Nucleotide transport and metabolism]; Region: PurN; COG0299
929102004425	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
929102004426	active site
929102004427	substrate binding site [chemical binding]; other site
929102004428	cosubstrate binding site; other site
929102004429	catalytic site [active]
929102004430	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
929102004431	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
929102004432	dimerization interface [polypeptide binding]; other site
929102004433	putative ATP binding site [chemical binding]; other site
929102004434	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
929102004435	Clp amino terminal domain; Region: Clp_N; pfam02861
929102004436	Clp amino terminal domain; Region: Clp_N; pfam02861
929102004437	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929102004438	Walker A motif; other site
929102004439	ATP binding site [chemical binding]; other site
929102004440	Walker B motif; other site
929102004441	arginine finger; other site
929102004442	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929102004443	Walker A motif; other site
929102004444	ATP binding site [chemical binding]; other site
929102004445	Walker B motif; other site
929102004446	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
929102004447	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
929102004448	NAD(P) binding site [chemical binding]; other site
929102004449	active site
929102004450	amidophosphoribosyltransferase; Provisional; Region: PRK07272
929102004451	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
929102004452	active site
929102004453	tetramer interface [polypeptide binding]; other site
929102004454	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
929102004455	active site
929102004456	phosphoribosylformylglycinamidine synthase II; Provisional; Region: PRK01213
929102004457	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
929102004458	dimerization interface [polypeptide binding]; other site
929102004459	ATP binding site [chemical binding]; other site
929102004460	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
929102004461	dimerization interface [polypeptide binding]; other site
929102004462	ATP binding site [chemical binding]; other site
929102004463	phosphoribosylformylglycinamidine synthase I; Provisional; Region: PRK03619
929102004464	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
929102004465	putative active site [active]
929102004466	catalytic triad [active]
929102004467	Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component [Nucleotide transport and metabolism]; Region: PurS; COG1828
929102004468	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
929102004469	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
929102004470	ATP binding site [chemical binding]; other site
929102004471	active site
929102004472	substrate binding site [chemical binding]; other site
929102004473	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
929102004474	Uncharacterized conserved protein [Function unknown]; Region: COG1359
929102004475	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
929102004476	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4334
929102004477	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
929102004478	classical (c) SDRs; Region: SDR_c; cd05233
929102004479	NAD(P) binding site [chemical binding]; other site
929102004480	active site
929102004481	putative transporter; Provisional; Region: PRK10504
929102004482	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929102004483	putative substrate translocation pore; other site
929102004484	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929102004485	Transcriptional regulators [Transcription]; Region: MarR; COG1846
929102004486	MarR family; Region: MarR_2; pfam12802
929102004487	thymidylate synthase; Reviewed; Region: thyA; PRK01827
929102004488	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
929102004489	dimerization interface [polypeptide binding]; other site
929102004490	active site
929102004491	formaldehyde dehydrogenase (FDH)-like; Region: FDH_like_ADH3; cd08287
929102004492	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
929102004493	catalytic Zn binding site [ion binding]; other site
929102004494	NAD(P) binding site [chemical binding]; other site
929102004495	structural Zn binding site [ion binding]; other site
929102004496	Enterocin A Immunity; Region: EntA_Immun; pfam08951
929102004497	Predicted membrane protein [Function unknown]; Region: COG4905
929102004498	Protein of unknown function (DUF1113); Region: DUF1113; pfam06541
929102004499	dihydroorotate dehydrogenase (subfamily 1) family protein; Region: pyrD_sub1_fam; TIGR01037
929102004500	Dihydroorotate dehydrogenase (DHOD) class 1A FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine...; Region: DHOD_1A_like; cd04741
929102004501	active site
929102004502	FMN binding site [chemical binding]; other site
929102004503	substrate binding site [chemical binding]; other site
929102004504	catalytic residues [active]
929102004505	homodimer interface [polypeptide binding]; other site
929102004506	Peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: MsrA; COG0225
929102004507	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
929102004508	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
929102004509	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
929102004510	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
929102004511	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929102004512	Walker A/P-loop; other site
929102004513	ATP binding site [chemical binding]; other site
929102004514	Q-loop/lid; other site
929102004515	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
929102004516	ABC transporter signature motif; other site
929102004517	Walker B; other site
929102004518	D-loop; other site
929102004519	ABC transporter; Region: ABC_tran_2; pfam12848
929102004520	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
929102004521	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
929102004522	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
929102004523	putative active site [active]
929102004524	metal binding site [ion binding]; metal-binding site
929102004525	Dipeptidase [Amino acid transport and metabolism]; Region: PepD; COG4690
929102004526	tRNA CCA-pyrophosphorylase; Provisional; Region: PRK13299
929102004527	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
929102004528	active site
929102004529	NTP binding site [chemical binding]; other site
929102004530	metal binding triad [ion binding]; metal-binding site
929102004531	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
929102004532	tRNA nucleotidyltransferase domain 2 putative; Region: tRNA_NucTran2_2; pfam13735
929102004533	Predicted acetyltransferase [General function prediction only]; Region: COG3981
929102004534	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
929102004535	Coenzyme A binding pocket [chemical binding]; other site
929102004536	dihydrodipicolinate reductase; Provisional; Region: PRK00048
929102004537	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
929102004538	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
929102004539	Uncharacterized protein conserved in bacteria [Function unknown]; Region: DegV; COG1307
929102004540	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
929102004541	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4835
929102004542	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
929102004543	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
929102004544	RimM N-terminal domain; Region: RimM; pfam01782
929102004545	PRC-barrel domain; Region: PRC; pfam05239
929102004546	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
929102004547	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
929102004548	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
929102004549	Protoheme ferro-lyase (ferrochelatase) [Coenzyme metabolism]; Region: HemH; COG0276
929102004550	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
929102004551	C-terminal domain interface [polypeptide binding]; other site
929102004552	active site
929102004553	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
929102004554	active site
929102004555	N-terminal domain interface [polypeptide binding]; other site
929102004556	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
929102004557	KH domain; Region: KH_4; pfam13083
929102004558	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
929102004559	Class II hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR); Region: HMG-CoA_reductase_classII; cd00644
929102004560	homodimer interface [polypeptide binding]; other site
929102004561	catalytic residues [active]
929102004562	NAD binding site [chemical binding]; other site
929102004563	substrate binding pocket [chemical binding]; other site
929102004564	flexible flap; other site
929102004565	putative acyltransferase; Provisional; Region: PRK05790
929102004566	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
929102004567	dimer interface [polypeptide binding]; other site
929102004568	active site
929102004569	"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are...; Region: init_cond_enzymes; cd00827
929102004570	3-hydroxy-3-methylglutaryl CoA synthase, prokaryotic clade; Region: HMG-CoA-S_prok; TIGR01835
929102004571	dimer interface [polypeptide binding]; other site
929102004572	active site
929102004573	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
929102004574	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
929102004575	active site
929102004576	trimer interface [polypeptide binding]; other site
929102004577	allosteric site; other site
929102004578	active site lid [active]
929102004579	hexamer (dimer of trimers) interface [polypeptide binding]; other site
929102004580	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
929102004581	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
929102004582	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
929102004583	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
929102004584	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
929102004585	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929102004586	non-specific DNA binding site [nucleotide binding]; other site
929102004587	salt bridge; other site
929102004588	sequence-specific DNA binding site [nucleotide binding]; other site
929102004589	WxL domain surface cell wall-binding; Region: WxL; pfam13731
929102004590	WxL domain surface cell wall-binding; Region: WxL; pfam13731
929102004591	WxL domain surface cell wall-binding; Region: WxL; pfam13731
929102004592	WxL domain surface cell wall-binding; Region: WxL; pfam13731
929102004593	GTPase CgtA; Reviewed; Region: obgE; PRK12297
929102004594	GTP1/OBG; Region: GTP1_OBG; pfam01018
929102004595	Obg GTPase; Region: Obg; cd01898
929102004596	G1 box; other site
929102004597	GTP/Mg2+ binding site [chemical binding]; other site
929102004598	Switch I region; other site
929102004599	G2 box; other site
929102004600	G3 box; other site
929102004601	Switch II region; other site
929102004602	G4 box; other site
929102004603	G5 box; other site
929102004604	Domain of unknown function (DUF1967); Region: DUF1967; pfam09269
929102004605	Cell division septal protein [Cell envelope biogenesis, outer membrane]; Region: FtsQ; COG1589
929102004606	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
929102004607	Cell division protein FtsQ; Region: FtsQ; pfam03799
929102004608	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
929102004609	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
929102004610	homodimer interface [polypeptide binding]; other site
929102004611	active site
929102004612	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK02472
929102004613	Alanine dehydrogenase/PNT, C-terminal domain; Region: AlaDh_PNT_C; smart01002
929102004614	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
929102004615	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
929102004616	Nitrogen regulatory protein PII [Amino acid transport and metabolism]; Region: GlnK; COG0347
929102004617	Nitrogen regulatory protein P-II; Region: P-II; smart00938
929102004618	Ammonia permease [Inorganic ion transport and metabolism]; Region: AmtB; COG0004
929102004619	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
929102004620	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
929102004621	dimerization interface [polypeptide binding]; other site
929102004622	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
929102004623	dimer interface [polypeptide binding]; other site
929102004624	phosphorylation site [posttranslational modification]
929102004625	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929102004626	ATP binding site [chemical binding]; other site
929102004627	Mg2+ binding site [ion binding]; other site
929102004628	G-X-G motif; other site
929102004629	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
929102004630	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929102004631	active site
929102004632	phosphorylation site [posttranslational modification]
929102004633	intermolecular recognition site; other site
929102004634	dimerization interface [polypeptide binding]; other site
929102004635	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
929102004636	DNA binding site [nucleotide binding]
929102004637	Predicted metal-binding, possibly nucleic acid-binding protein [General function prediction only]; Region: COG1399
929102004638	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
929102004639	conserved hypothetical protein; Region: TIGR02328
929102004640	Pyrimidine dimer DNA glycosylase; Region: Pyr_excise; pfam03013
929102004641	phosphodiesterase YaeI; Provisional; Region: PRK11340
929102004642	Protein of unknown function (DUF3139); Region: DUF3139; pfam11337
929102004643	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
929102004644	putative active site [active]
929102004645	putative metal binding site [ion binding]; other site
929102004646	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
929102004647	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
929102004648	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
929102004649	catalytic site [active]
929102004650	subunit interface [polypeptide binding]; other site
929102004651	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
929102004652	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
929102004653	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
929102004654	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
929102004655	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
929102004656	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
929102004657	active site
929102004658	Peptidase M50B-like; Region: Peptidase_M50B; pfam13398
929102004659	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
929102004660	dimerization interface [polypeptide binding]; other site
929102004661	putative DNA binding site [nucleotide binding]; other site
929102004662	putative Zn2+ binding site [ion binding]; other site
929102004663	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
929102004664	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
929102004665	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
929102004666	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
929102004667	putative catalytic cysteine [active]
929102004668	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
929102004669	nucleotide binding site [chemical binding]; other site
929102004670	homotetrameric interface [polypeptide binding]; other site
929102004671	putative phosphate binding site [ion binding]; other site
929102004672	putative allosteric binding site; other site
929102004673	Uncharacterized conserved protein [Function unknown]; Region: COG2461
929102004674	Family of unknown function (DUF438); Region: DUF438; pfam04282
929102004675	Hemerythrin HHE cation binding domain; Region: Hemerythrin; pfam01814
929102004676	Domain of unknown function (DUF1858); Region: DUF1858; pfam08984
929102004677	Predicted membrane protein [Function unknown]; Region: COG4392
929102004678	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
929102004679	Predicted dinucleotide-binding enzymes [General function prediction only]; Region: COG2085
929102004680	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
929102004681	spermidine N1-acetyltransferase; Provisional; Region: PRK15130
929102004682	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929102004683	Coenzyme A binding pocket [chemical binding]; other site
929102004684	signal recognition particle protein; Provisional; Region: PRK10867
929102004685	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
929102004686	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
929102004687	P loop; other site
929102004688	GTP binding site [chemical binding]; other site
929102004689	Signal peptide binding domain; Region: SRP_SPB; pfam02978
929102004690	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
929102004691	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
929102004692	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
929102004693	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
929102004694	Uncharacterized membrane protein [Function unknown]; Region: SapB; COG1285
929102004695	MgtC family; Region: MgtC; pfam02308
929102004696	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
929102004697	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
929102004698	dimer interface [polypeptide binding]; other site
929102004699	active site
929102004700	catalytic residue [active]
929102004701	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_18; cd04677
929102004702	nudix motif; other site
929102004703	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
929102004704	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
929102004705	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
929102004706	amphipathic channel; other site
929102004707	Asn-Pro-Ala signature motifs; other site
929102004708	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
929102004709	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
929102004710	TPP-binding site [chemical binding]; other site
929102004711	dimer interface [polypeptide binding]; other site
929102004712	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
929102004713	PYR/PP interface [polypeptide binding]; other site
929102004714	dimer interface [polypeptide binding]; other site
929102004715	TPP binding site [chemical binding]; other site
929102004716	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
929102004717	2-keto-3-deoxy-6-phosphogluconate aldolase [Carbohydrate transport and metabolism]; Region: Eda; COG0800
929102004718	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
929102004719	active site
929102004720	intersubunit interface [polypeptide binding]; other site
929102004721	catalytic residue [active]
929102004722	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
929102004723	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
929102004724	substrate binding site [chemical binding]; other site
929102004725	ATP binding site [chemical binding]; other site
929102004726	Glucuronate isomerase; Region: UxaC; pfam02614
929102004727	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
929102004728	Aldose 1-epimerase, similar to Lactococcus lactis lacX; Region: Aldose_epim_lacX; cd09024
929102004729	active site
929102004730	catalytic residues [active]
929102004731	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
929102004732	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929102004733	putative substrate translocation pore; other site
929102004734	mannonate dehydratase; Provisional; Region: PRK03906
929102004735	mannonate dehydratase; Region: uxuA; TIGR00695
929102004736	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
929102004737	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
929102004738	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
929102004739	Transcriptional regulators [Transcription]; Region: GntR; COG1802
929102004740	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
929102004741	DNA-binding site [nucleotide binding]; DNA binding site
929102004742	FCD domain; Region: FCD; pfam07729
929102004743	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
929102004744	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929102004745	putative substrate translocation pore; other site
929102004746	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
929102004747	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
929102004748	ligand binding site [chemical binding]; other site
929102004749	dimerization interface [polypeptide binding]; other site
929102004750	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
929102004751	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
929102004752	TM-ABC transporter signature motif; other site
929102004753	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
929102004754	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929102004755	Walker A/P-loop; other site
929102004756	ATP binding site [chemical binding]; other site
929102004757	Q-loop/lid; other site
929102004758	ABC transporter signature motif; other site
929102004759	Walker B; other site
929102004760	D-loop; other site
929102004761	H-loop/switch region; other site
929102004762	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
929102004763	D-ribose pyranase; Provisional; Region: PRK11797
929102004764	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
929102004765	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
929102004766	substrate binding site [chemical binding]; other site
929102004767	dimer interface [polypeptide binding]; other site
929102004768	ATP binding site [chemical binding]; other site
929102004769	Transcriptional regulators [Transcription]; Region: PurR; COG1609
929102004770	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
929102004771	DNA binding site [nucleotide binding]
929102004772	domain linker motif; other site
929102004773	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
929102004774	dimerization interface [polypeptide binding]; other site
929102004775	ligand binding site [chemical binding]; other site
929102004776	adenylosuccinate lyase; Provisional; Region: PRK07492
929102004777	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
929102004778	tetramer interface [polypeptide binding]; other site
929102004779	active site
929102004780	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
929102004781	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
929102004782	active site
929102004783	catalytic residue [active]
929102004784	dimer interface [polypeptide binding]; other site
929102004785	Protein of unknown function (DUF2969); Region: DUF2969; pfam11184
929102004786	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
929102004787	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
929102004788	catalytic residues [active]
929102004789	Mismatch repair ATPase (MutS family) [DNA replication, recombination, and repair]; Region: COG1193
929102004790	MutS domain III; Region: MutS_III; pfam05192
929102004791	ATP-binding cassette domain of MutS2; Region: ABC_MutS2; cd03280
929102004792	Walker A/P-loop; other site
929102004793	ATP binding site [chemical binding]; other site
929102004794	Q-loop/lid; other site
929102004795	ABC transporter signature motif; other site
929102004796	Walker B; other site
929102004797	D-loop; other site
929102004798	H-loop/switch region; other site
929102004799	Smr domain; Region: Smr; pfam01713
929102004800	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
929102004801	Colicin V production protein; Region: Colicin_V; pfam02674
929102004802	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
929102004803	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
929102004804	catabolite control protein A; Region: ccpA; TIGR01481
929102004805	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
929102004806	DNA binding site [nucleotide binding]
929102004807	domain linker motif; other site
929102004808	Ligand-binding domain of the catabolite control protein A (CcpA), which functions as the major transcriptional regulator of carbon catabolite repression/regulation; Region: PBP1_CcpA_like; cd06298
929102004809	dimerization interface [polypeptide binding]; other site
929102004810	effector binding site; other site
929102004811	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
929102004812	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
929102004813	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
929102004814	active site
929102004815	AAA ATPase containing von Willebrand factor type A (vWA) domain [General function prediction only]; Region: MDN1; COG5271
929102004816	Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0116
929102004817	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
929102004818	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
929102004819	cell division protein GpsB; Provisional; Region: PRK14127
929102004820	DivIVA domain; Region: DivI1A_domain; TIGR03544
929102004821	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
929102004822	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
929102004823	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
929102004824	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
929102004825	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
929102004826	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
929102004827	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
929102004828	active site
929102004829	motif I; other site
929102004830	motif II; other site
929102004831	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
929102004832	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
929102004833	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
929102004834	ATP-binding site [chemical binding]; other site
929102004835	Sugar specificity; other site
929102004836	Pyrimidine base specificity; other site
929102004837	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
929102004838	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
929102004839	Cpl-7 lysozyme C-terminal domain; Region: Cpl-7; smart01095
929102004840	Transglycosylase-like domain; Region: Transglycosylas; pfam06737
929102004841	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Provisional; Region: PRK13387
929102004842	UbiA prenyltransferase family; Region: UbiA; pfam01040
929102004843	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
929102004844	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
929102004845	Cl- selectivity filter; other site
929102004846	Cl- binding residues [ion binding]; other site
929102004847	pore gating glutamate residue; other site
929102004848	dimer interface [polypeptide binding]; other site
929102004849	H+/Cl- coupling transport residue; other site
929102004850	TrkA-C domain; Region: TrkA_C; pfam02080
929102004851	Enterocin A Immunity; Region: EntA_Immun; pfam08951
929102004852	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929102004853	non-specific DNA binding site [nucleotide binding]; other site
929102004854	salt bridge; other site
929102004855	sequence-specific DNA binding site [nucleotide binding]; other site
929102004856	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
929102004857	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
929102004858	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929102004859	S-adenosylmethionine binding site [chemical binding]; other site
929102004860	Predicted membrane protein [Function unknown]; Region: COG1511
929102004861	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
929102004862	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
929102004863	dimer interface [polypeptide binding]; other site
929102004864	YhgE/Pip C-terminal domain; Region: pip_yhgE_Cterm; TIGR03062
929102004865	6-phospho-beta-glucosidase; Reviewed; Region: arb; PRK09593
929102004866	beta-galactosidase; Region: BGL; TIGR03356
929102004867	Uncharacterized conserved protein [Function unknown]; Region: COG0759
929102004868	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
929102004869	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
929102004870	dimer interface [polypeptide binding]; other site
929102004871	phosphorylation site [posttranslational modification]
929102004872	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929102004873	ATP binding site [chemical binding]; other site
929102004874	Mg2+ binding site [ion binding]; other site
929102004875	G-X-G motif; other site
929102004876	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
929102004877	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929102004878	active site
929102004879	phosphorylation site [posttranslational modification]
929102004880	intermolecular recognition site; other site
929102004881	dimerization interface [polypeptide binding]; other site
929102004882	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
929102004883	DNA binding site [nucleotide binding]
929102004884	Transcriptional regulators [Transcription]; Region: PurR; COG1609
929102004885	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
929102004886	DNA binding site [nucleotide binding]
929102004887	domain linker motif; other site
929102004888	Ligand-binding domain of uncharacterized transcription regulator ycjW which is a member of the LacI-GalR family repressors; Region: PBP1_ycjW_transcription_regulator_like; cd06294
929102004889	putative dimerization interface [polypeptide binding]; other site
929102004890	putative ligand binding site [chemical binding]; other site
929102004891	maltose phosphorylase; Provisional; Region: PRK13807
929102004892	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
929102004893	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
929102004894	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
929102004895	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
929102004896	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
929102004897	Ca binding site [ion binding]; other site
929102004898	active site
929102004899	catalytic site [active]
929102004900	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
929102004901	Alpha amylase catalytic domain found in bacterial Alpha-amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac2_AmyA; cd11316
929102004902	Ca binding site [ion binding]; other site
929102004903	active site
929102004904	catalytic site [active]
929102004905	maltose O-acetyltransferase; Provisional; Region: PRK10092
929102004906	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
929102004907	active site
929102004908	substrate binding site [chemical binding]; other site
929102004909	trimer interface [polypeptide binding]; other site
929102004910	CoA binding site [chemical binding]; other site
929102004911	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
929102004912	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
929102004913	Ca binding site [ion binding]; other site
929102004914	active site
929102004915	catalytic site [active]
929102004916	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
929102004917	homodimer interface [polypeptide binding]; other site
929102004918	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
929102004919	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
929102004920	active site
929102004921	homodimer interface [polypeptide binding]; other site
929102004922	catalytic site [active]
929102004923	Maltose-binding periplasmic proteins/domains [Carbohydrate transport and metabolism]; Region: MalE; COG2182
929102004924	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
929102004925	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
929102004926	dimer interface [polypeptide binding]; other site
929102004927	conserved gate region; other site
929102004928	putative PBP binding loops; other site
929102004929	ABC-ATPase subunit interface; other site
929102004930	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
929102004931	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
929102004932	dimer interface [polypeptide binding]; other site
929102004933	conserved gate region; other site
929102004934	putative PBP binding loops; other site
929102004935	ABC-ATPase subunit interface; other site
929102004936	Predicted periplasmic/secreted protein [Function unknown]; Region: COG3477
929102004937	Enterocin A Immunity; Region: EntA_Immun; pfam08951
929102004938	LssY C-terminus; Region: LssY_C; pfam14067
929102004939	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
929102004940	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
929102004941	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
929102004942	dimerization interface [polypeptide binding]; other site
929102004943	putative DNA binding site [nucleotide binding]; other site
929102004944	putative Zn2+ binding site [ion binding]; other site
929102004945	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
929102004946	Old yellow enzyme (OYE)-related FMN binding domain, group 4.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as...; Region: OYE_like_4_FMN; cd04735
929102004947	putative active site [active]
929102004948	putative FMN binding site [chemical binding]; other site
929102004949	putative substrate binding site [chemical binding]; other site
929102004950	putative catalytic residue [active]
929102004951	carbamate kinase; Reviewed; Region: PRK12686
929102004952	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
929102004953	putative substrate binding site [chemical binding]; other site
929102004954	nucleotide binding site [chemical binding]; other site
929102004955	nucleotide binding site [chemical binding]; other site
929102004956	homodimer interface [polypeptide binding]; other site
929102004957	agmatine deiminase; Provisional; Region: PRK13551
929102004958	agmatine deiminase; Region: agmatine_aguA; TIGR03380
929102004959	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
929102004960	Helix-turn-helix domain; Region: HTH_38; pfam13936
929102004961	Integrase core domain; Region: rve; pfam00665
929102004962	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
929102004963	putrescine carbamoyltransferase; Provisional; Region: PRK02255
929102004964	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
929102004965	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
929102004966	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
929102004967	DNA binding residues [nucleotide binding]
929102004968	dimerization interface [polypeptide binding]; other site
929102004969	Transcriptional regulator [Transcription]; Region: LytR; COG1316
929102004970	cytidylate kinase; Provisional; Region: cmk; PRK00023
929102004971	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
929102004972	CMP-binding site; other site
929102004973	The sites determining sugar specificity; other site
929102004974	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
929102004975	Ferredoxin [Energy production and conversion]; Region: Fer; COG1141
929102004976	Protein of unknown function (DUF1271); Region: DUF1271; cl01443
929102004977	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
929102004978	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
929102004979	active pocket/dimerization site; other site
929102004980	active site
929102004981	phosphorylation site [posttranslational modification]
929102004982	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
929102004983	active site
929102004984	phosphorylation site [posttranslational modification]
929102004985	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
929102004986	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
929102004987	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4687
929102004988	Uncharacterized conserved protein [Function unknown]; Region: COG1284
929102004989	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4687
929102004990	seryl-tRNA synthetase; Provisional; Region: PRK05431
929102004991	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
929102004992	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
929102004993	dimer interface [polypeptide binding]; other site
929102004994	active site
929102004995	motif 1; other site
929102004996	motif 2; other site
929102004997	motif 3; other site
929102004998	Microcin C7 self-immunity protein determines resistance to exogenous microcin C7; Region: Peptidase_S66_mccF_like; cd07062
929102004999	putative dimer interface [polypeptide binding]; other site
929102005000	catalytic triad [active]
929102005001	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
929102005002	catalytic core [active]
929102005003	phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135
929102005004	PhoU domain; Region: PhoU; pfam01895
929102005005	PhoU domain; Region: PhoU; pfam01895
929102005006	phosphate transporter ATP-binding protein; Provisional; Region: PRK14239
929102005007	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
929102005008	Walker A/P-loop; other site
929102005009	ATP binding site [chemical binding]; other site
929102005010	Q-loop/lid; other site
929102005011	ABC transporter signature motif; other site
929102005012	Walker B; other site
929102005013	D-loop; other site
929102005014	H-loop/switch region; other site
929102005015	phosphate transporter ATP-binding protein; Provisional; Region: PRK14237
929102005016	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
929102005017	Walker A/P-loop; other site
929102005018	ATP binding site [chemical binding]; other site
929102005019	Q-loop/lid; other site
929102005020	ABC transporter signature motif; other site
929102005021	Walker B; other site
929102005022	D-loop; other site
929102005023	H-loop/switch region; other site
929102005024	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstA; COG0581
929102005025	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
929102005026	dimer interface [polypeptide binding]; other site
929102005027	conserved gate region; other site
929102005028	putative PBP binding loops; other site
929102005029	ABC-ATPase subunit interface; other site
929102005030	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573
929102005031	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
929102005032	dimer interface [polypeptide binding]; other site
929102005033	conserved gate region; other site
929102005034	putative PBP binding loops; other site
929102005035	ABC-ATPase subunit interface; other site
929102005036	PBP superfamily domain; Region: PBP_like_2; cl17296
929102005037	PBP superfamily domain; Region: PBP_like_2; cl17296
929102005038	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
929102005039	SmpB-tmRNA interface; other site
929102005040	Isoamyl-acetate hydrolyzing esterase-like proteins. SGNH_hydrolase subfamily similar to the Saccharomyces cerevisiae IAH1. IAH1 may be the major esterase that hydrolyses isoamyl acetate in sake mash.  The SGNH-family of hydrolases is a diverse family of...; Region: Isoamyl_acetate_hydrolase_like; cd01838
929102005041	catalytic triad [active]
929102005042	oxyanion hole [active]
929102005043	active site
929102005044	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
929102005045	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
929102005046	motif 1; other site
929102005047	active site
929102005048	motif 2; other site
929102005049	motif 3; other site
929102005050	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
929102005051	DHHA1 domain; Region: DHHA1; pfam02272
929102005052	foldase protein PrsA; Reviewed; Region: PRK12450
929102005053	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
929102005054	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929102005055	S-adenosylmethionine binding site [chemical binding]; other site
929102005056	Oligoendopeptidase F [Amino acid transport and metabolism]; Region: COG1164
929102005057	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_3; cd09608
929102005058	active site
929102005059	Zn binding site [ion binding]; other site
929102005060	Competence protein CoiA-like family, contains a predicted nuclease    domain [General function prediction only]; Region: CoiA; COG4469
929102005061	Uncharacterized conserved protein [Function unknown]; Region: COG1434
929102005062	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
929102005063	putative active site [active]
929102005064	Alpha/beta hydrolase of unknown function (DUF915); Region: DUF915; pfam06028
929102005065	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
929102005066	Sulfate transporter family; Region: Sulfate_transp; pfam00916
929102005067	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
929102005068	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
929102005069	active site
929102005070	motif I; other site
929102005071	motif II; other site
929102005072	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
929102005073	CoB--CoM heterodisulfide reductase, subunit B; Region: CoB_CoM_SS_B; TIGR03288
929102005074	Cysteine-rich domain; Region: CCG; pfam02754
929102005075	Cysteine-rich domain; Region: CCG; pfam02754
929102005076	Uncharacterized conserved protein containing a ferredoxin-like domain [Energy production and conversion]; Region: COG1139
929102005077	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
929102005078	Uncharacterized conserved protein [Function unknown]; Region: COG1556
929102005079	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
929102005080	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
929102005081	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
929102005082	DNA-binding site [nucleotide binding]; DNA binding site
929102005083	RNA-binding motif; other site
929102005084	SecA binding site; other site
929102005085	Preprotein binding site; other site
929102005086	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cl00251
929102005087	Predicted membrane-associated HD superfamily hydrolase [General function prediction only]; Region: COG1480
929102005088	chromosome segregation protein SMC, primarily archaeal type; Region: SMC_prok_A; TIGR02169
929102005089	BRO family, N-terminal domain; Region: Bro-N; smart01040
929102005090	1-deoxy-D-xylulose-5-phosphate reductoisomerase; Region: PLN02696
929102005091	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929102005092	salt bridge; other site
929102005093	non-specific DNA binding site [nucleotide binding]; other site
929102005094	sequence-specific DNA binding site [nucleotide binding]; other site
929102005095	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
929102005096	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929102005097	non-specific DNA binding site [nucleotide binding]; other site
929102005098	salt bridge; other site
929102005099	sequence-specific DNA binding site [nucleotide binding]; other site
929102005100	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
929102005101	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
929102005102	Int/Topo IB signature motif; other site
929102005103	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
929102005104	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
929102005105	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
929102005106	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
929102005107	Zn2+ binding site [ion binding]; other site
929102005108	Mg2+ binding site [ion binding]; other site
929102005109	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
929102005110	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
929102005111	H3TH domains of structure-specific 5' nucleases (or flap endonuclease-1-like) involved in DNA replication, repair, and recombination; Region: H3TH_StructSpec-5'-nucleases; cl14815
929102005112	AAA domain; Region: AAA_30; pfam13604
929102005113	Family description; Region: UvrD_C_2; pfam13538
929102005114	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
929102005115	catalytic core [active]
929102005116	prephenate dehydratase; Provisional; Region: PRK11898
929102005117	Prephenate dehydratase; Region: PDT; pfam00800
929102005118	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
929102005119	putative L-Phe binding site [chemical binding]; other site
929102005120	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
929102005121	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
929102005122	ADP binding site [chemical binding]; other site
929102005123	magnesium binding site [ion binding]; other site
929102005124	putative shikimate binding site; other site
929102005125	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
929102005126	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
929102005127	hinge; other site
929102005128	active site
929102005129	prephenate dehydrogenase; Validated; Region: PRK06545
929102005130	prephenate dehydrogenase; Validated; Region: PRK08507
929102005131	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
929102005132	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
929102005133	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929102005134	ATP binding site [chemical binding]; other site
929102005135	Mg2+ binding site [ion binding]; other site
929102005136	G-X-G motif; other site
929102005137	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
929102005138	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929102005139	active site
929102005140	phosphorylation site [posttranslational modification]
929102005141	intermolecular recognition site; other site
929102005142	dimerization interface [polypeptide binding]; other site
929102005143	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
929102005144	DNA binding site [nucleotide binding]
929102005145	Glycopeptide antibiotics resistance protein [Defense mechanisms]; Region: VanZ; COG4767
929102005146	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
929102005147	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
929102005148	Walker A/P-loop; other site
929102005149	ATP binding site [chemical binding]; other site
929102005150	Q-loop/lid; other site
929102005151	ABC transporter signature motif; other site
929102005152	Walker B; other site
929102005153	D-loop; other site
929102005154	H-loop/switch region; other site
929102005155	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5294
929102005156	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
929102005157	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
929102005158	Tetramer interface [polypeptide binding]; other site
929102005159	active site
929102005160	FMN-binding site [chemical binding]; other site
929102005161	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
929102005162	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
929102005163	active site
929102005164	motif I; other site
929102005165	motif II; other site
929102005166	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4493
929102005167	Protein of unknown function (DUF1054); Region: DUF1054; pfam06335
929102005168	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
929102005169	Protein of unknown function, DUF606; Region: DUF606; pfam04657
929102005170	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
929102005171	Iron-containing alcohol dehydrogenase; Region: Fe-ADH; pfam00465
929102005172	active site
929102005173	dimer interface [polypeptide binding]; other site
929102005174	metal binding site [ion binding]; metal-binding site
929102005175	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
929102005176	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
929102005177	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
929102005178	shikimate binding site; other site
929102005179	NAD(P) binding site [chemical binding]; other site
929102005180	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
929102005181	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
929102005182	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
929102005183	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
929102005184	substrate binding pocket [chemical binding]; other site
929102005185	membrane-bound complex binding site; other site
929102005186	hinge residues; other site
929102005187	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
929102005188	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
929102005189	substrate binding pocket [chemical binding]; other site
929102005190	membrane-bound complex binding site; other site
929102005191	hinge residues; other site
929102005192	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
929102005193	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
929102005194	dimer interface [polypeptide binding]; other site
929102005195	conserved gate region; other site
929102005196	putative PBP binding loops; other site
929102005197	ABC-ATPase subunit interface; other site
929102005198	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
929102005199	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
929102005200	Walker A/P-loop; other site
929102005201	ATP binding site [chemical binding]; other site
929102005202	Q-loop/lid; other site
929102005203	ABC transporter signature motif; other site
929102005204	Walker B; other site
929102005205	D-loop; other site
929102005206	H-loop/switch region; other site
929102005207	legume lectins; Region: lectin_L-type; cl14058
929102005208	homotetramer interaction site [polypeptide binding]; other site
929102005209	carbohydrate binding site [chemical binding]; other site
929102005210	metal binding site [ion binding]; metal-binding site
929102005211	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
929102005212	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
929102005213	gamma subunit interface [polypeptide binding]; other site
929102005214	epsilon subunit interface [polypeptide binding]; other site
929102005215	LBP interface [polypeptide binding]; other site
929102005216	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
929102005217	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
929102005218	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
929102005219	alpha subunit interaction interface [polypeptide binding]; other site
929102005220	Walker A motif; other site
929102005221	ATP binding site [chemical binding]; other site
929102005222	Walker B motif; other site
929102005223	inhibitor binding site; inhibition site
929102005224	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
929102005225	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
929102005226	core domain interface [polypeptide binding]; other site
929102005227	delta subunit interface [polypeptide binding]; other site
929102005228	epsilon subunit interface [polypeptide binding]; other site
929102005229	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
929102005230	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
929102005231	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
929102005232	beta subunit interaction interface [polypeptide binding]; other site
929102005233	Walker A motif; other site
929102005234	ATP binding site [chemical binding]; other site
929102005235	Walker B motif; other site
929102005236	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
929102005237	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
929102005238	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
929102005239	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
929102005240	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
929102005241	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
929102005242	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
929102005243	F0F1 ATP synthase subunit C; Provisional; Region: PRK13466
929102005244	Predicted esterase [General function prediction only]; Region: COG0627
929102005245	S-formylglutathione hydrolase; Region: PLN02442
929102005246	Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658
929102005247	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
929102005248	Competence protein; Region: Competence; pfam03772
929102005249	Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333
929102005250	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
929102005251	SLBB domain; Region: SLBB; pfam10531
929102005252	comEA protein; Region: comE; TIGR01259
929102005253	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786
929102005254	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
929102005255	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
929102005256	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4152
929102005257	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929102005258	Walker A/P-loop; other site
929102005259	ATP binding site [chemical binding]; other site
929102005260	Q-loop/lid; other site
929102005261	ABC transporter signature motif; other site
929102005262	Walker B; other site
929102005263	D-loop; other site
929102005264	H-loop/switch region; other site
929102005265	Domain of unknown function (DUF4162); Region: DUF4162; pfam13732
929102005266	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
929102005267	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
929102005268	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
929102005269	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
929102005270	transmembrane helices; other site
929102005271	Putative transcription activator [Transcription]; Region: TenA; COG0819
929102005272	Zinc finger domain containing protein (CHY type) [Function unknown]; Region: COG4357
929102005273	CHY zinc finger; Region: zf-CHY; pfam05495
929102005274	Biotin operon repressor [Transcription]; Region: BirA; COG1654
929102005275	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
929102005276	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
929102005277	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
929102005278	Uncharacterized conserved protein [General function prediction only]; Region: BioY; COG1268
929102005279	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
929102005280	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
929102005281	acyl-activating enzyme (AAE) consensus motif; other site
929102005282	AMP binding site [chemical binding]; other site
929102005283	active site
929102005284	CoA binding site [chemical binding]; other site
929102005285	acetyl-CoA acetyltransferases; Region: AcCoA-C-Actrans; TIGR01930
929102005286	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
929102005287	dimer interface [polypeptide binding]; other site
929102005288	active site
929102005289	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
929102005290	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
929102005291	NAD(P) binding site [chemical binding]; other site
929102005292	active site
929102005293	putative enoyl-[acyl-carrier-protein] reductase II; Region: enACPred_II; TIGR03151
929102005294	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
929102005295	FMN binding site [chemical binding]; other site
929102005296	substrate binding site [chemical binding]; other site
929102005297	putative catalytic residue [active]
929102005298	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814; cl03223
929102005299	FeS assembly protein SufB; Region: sufB; TIGR01980
929102005300	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
929102005301	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
929102005302	trimerization site [polypeptide binding]; other site
929102005303	active site
929102005304	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
929102005305	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
929102005306	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
929102005307	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
929102005308	catalytic residue [active]
929102005309	Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]; Region: SufB; COG0719
929102005310	FeS assembly protein SufD; Region: sufD; TIGR01981
929102005311	Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones]; Region: sufC; COG0396
929102005312	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
929102005313	Walker A/P-loop; other site
929102005314	ATP binding site [chemical binding]; other site
929102005315	Q-loop/lid; other site
929102005316	ABC transporter signature motif; other site
929102005317	Walker B; other site
929102005318	D-loop; other site
929102005319	H-loop/switch region; other site
929102005320	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
929102005321	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
929102005322	Mg++ binding site [ion binding]; other site
929102005323	putative catalytic motif [active]
929102005324	substrate binding site [chemical binding]; other site
929102005325	Negative regulator of genetic competence, sporulation and motility [Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Cell motility and secretion]; Region: MecA; COG4862
929102005326	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
929102005327	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
929102005328	Walker A/P-loop; other site
929102005329	ATP binding site [chemical binding]; other site
929102005330	Q-loop/lid; other site
929102005331	ABC transporter signature motif; other site
929102005332	Walker B; other site
929102005333	D-loop; other site
929102005334	H-loop/switch region; other site
929102005335	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
929102005336	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
929102005337	dimer interface [polypeptide binding]; other site
929102005338	conserved gate region; other site
929102005339	putative PBP binding loops; other site
929102005340	ABC-ATPase subunit interface; other site
929102005341	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
929102005342	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
929102005343	DNA-directed RNA polymerase subunit beta'; Provisional; Region: PRK00566
929102005344	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
929102005345	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
929102005346	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
929102005347	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
929102005348	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
929102005349	Rpb1 (beta') - Rpb6 (omega) interaction site [polypeptide binding]; other site
929102005350	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
929102005351	G-loop; other site
929102005352	DNA binding site [nucleotide binding]
929102005353	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
929102005354	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
929102005355	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
929102005356	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
929102005357	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
929102005358	RPB12 interaction site [polypeptide binding]; other site
929102005359	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
929102005360	RPB10 interaction site [polypeptide binding]; other site
929102005361	RPB1 interaction site [polypeptide binding]; other site
929102005362	RPB11 interaction site [polypeptide binding]; other site
929102005363	RPB3 interaction site [polypeptide binding]; other site
929102005364	RPB12 interaction site [polypeptide binding]; other site
929102005365	Pleiotropic transcriptional repressor [Transcription]; Region: CodY; COG4465
929102005366	CodY GAF-like domain; Region: CodY; pfam06018
929102005367	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
929102005368	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
929102005369	non-specific DNA binding site [nucleotide binding]; other site
929102005370	salt bridge; other site
929102005371	sequence-specific DNA binding site [nucleotide binding]; other site
929102005372	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
929102005373	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
929102005374	active site
929102005375	Zn binding site [ion binding]; other site
929102005376	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
929102005377	active site
929102005378	DNA binding site [nucleotide binding]
929102005379	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
929102005380	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
929102005381	UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase; Provisional; Region: PRK14022
929102005382	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
929102005383	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
929102005384	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
929102005385	ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422
929102005386	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
929102005387	NAD binding site [chemical binding]; other site
929102005388	substrate binding site [chemical binding]; other site
929102005389	catalytic Zn binding site [ion binding]; other site
929102005390	tetramer interface [polypeptide binding]; other site
929102005391	structural Zn binding site [ion binding]; other site
929102005392	Superfamily II DNA helicase [DNA replication, recombination, and repair]; Region: RecQ; COG0514
929102005393	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
929102005394	ATP binding site [chemical binding]; other site
929102005395	putative Mg++ binding site [ion binding]; other site
929102005396	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
929102005397	nucleotide binding region [chemical binding]; other site
929102005398	ATP-binding site [chemical binding]; other site
929102005399	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
929102005400	HRDC domain; Region: HRDC; pfam00570
929102005401	inner membrane transporter YjeM; Provisional; Region: PRK15238
929102005402	peptidase T; Region: peptidase-T; TIGR01882
929102005403	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
929102005404	metal binding site [ion binding]; metal-binding site
929102005405	dimer interface [polypeptide binding]; other site
929102005406	Domain of unknown function (DUF1803); Region: DUF1803; pfam08820
929102005407	Domain of unknown function (DUF1803); Region: DUF1803; pfam08820
929102005408	putative manganese-dependent inorganic pyrophosphatase; Provisional; Region: PRK05427
929102005409	DHH family; Region: DHH; pfam01368
929102005410	DHHA2 domain; Region: DHHA2; pfam02833
929102005411	pyruvate formate-lyase 1-activating enzyme; Region: PFLA; TIGR02493
929102005412	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
929102005413	FeS/SAM binding site; other site
929102005414	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
929102005415	Domain of unknown function DUF21; Region: DUF21; pfam01595
929102005416	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
929102005417	Transporter associated domain; Region: CorC_HlyC; smart01091
929102005418	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
929102005419	Domain of unknown function DUF20; Region: UPF0118; pfam01594
929102005420	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
929102005421	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929102005422	Coenzyme A binding pocket [chemical binding]; other site
929102005423	Uncharacterized subfamily of Uracil-DNA glycosylases; Region: UDG_like_1; cd10033
929102005424	putative uracil binding site [chemical binding]; other site
929102005425	putative active site [active]
929102005426	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
929102005427	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
929102005428	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
929102005429	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
929102005430	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
929102005431	catalytic core [active]
929102005432	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
929102005433	GIY-YIG motif/motif A; other site
929102005434	putative active site [active]
929102005435	putative metal binding site [ion binding]; other site
929102005436	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
929102005437	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
929102005438	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
929102005439	Thiamine pyrophosphokinase [Coenzyme metabolism]; Region: THI80; COG1564
929102005440	Thiamine pyrophosphokinase; Region: TPK; cd07995
929102005441	active site
929102005442	dimerization interface [polypeptide binding]; other site
929102005443	thiamine binding site [chemical binding]; other site
929102005444	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in a group of uncharacterized proteins from bacteria and archaea; Region: NTP-PPase_u4; cd11541
929102005445	putative metal binding site [ion binding]; other site
929102005446	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
929102005447	AsnRS_cyto_like_N: N-terminal, anticodon recognition domain of the type found in human and Saccharomyces cerevisiae cytoplasmic asparaginyl-tRNA synthetase (AsnRS), in Brugia malayai AsnRs and, in various putative bacterial AsnRSs.  This domain is a...; Region: AsnRS_cyto_like_N; cd04323
929102005448	putative dimer interface [polypeptide binding]; other site
929102005449	putative anticodon binding site; other site
929102005450	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
929102005451	homodimer interface [polypeptide binding]; other site
929102005452	motif 1; other site
929102005453	motif 2; other site
929102005454	active site
929102005455	motif 3; other site
929102005456	GIY-YIG domain of LuxR and ArsR family transcriptional regulators, and uncharacterized hypothetical proteins found in bacteria; Region: GIY-YIG_LuxR_like; cd10451
929102005457	GIY-YIG motif/motif A; other site
929102005458	aspartate aminotransferase; Provisional; Region: PRK05764
929102005459	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
929102005460	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929102005461	homodimer interface [polypeptide binding]; other site
929102005462	catalytic residue [active]
929102005463	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5353
929102005464	DnaQ family exonuclease/DinG family helicase, putative; Region: dinG_rel; TIGR01407
929102005465	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
929102005466	active site
929102005467	catalytic site [active]
929102005468	substrate binding site [chemical binding]; other site
929102005469	DEAD/DEAH box helicase; Region: DEAD; pfam00270
929102005470	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
929102005471	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
929102005472	Ligand Binding Site [chemical binding]; other site
929102005473	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
929102005474	Domain of unknown function DUF21; Region: DUF21; pfam01595
929102005475	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
929102005476	Transporter associated domain; Region: CorC_HlyC; smart01091
929102005477	Linear amide C-N hydrolases, choloylglycine hydrolase family; Region: CBAH; pfam02275
929102005478	Penicillin V acylase (PVA), also known as conjugated bile salt acid hydrolase (CBAH), catalyzes the hydrolysis of penicillin V to yield 6-amino penicillanic acid (6-APA), an important key intermediate of semisynthetic penicillins.  PVA has an N-terminal...; Region: Ntn_PVA; cd00542
929102005479	active site
929102005480	Protein tyrosine/serine phosphatase [Signal transduction mechanisms]; Region: COG2365
929102005481	Tyrosine phosphatase family C-terminal region; Region: Y_phosphatase3C; pfam13348
929102005482	The substrate binding component of an ABC-type lactococcal OppA-like transport system contains; Region: PBP2_Lactococcal_OppA_like; cd08510
929102005483	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
929102005484	peptide binding site [polypeptide binding]; other site
929102005485	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
929102005486	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
929102005487	dimer interface [polypeptide binding]; other site
929102005488	conserved gate region; other site
929102005489	putative PBP binding loops; other site
929102005490	ABC-ATPase subunit interface; other site
929102005491	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
929102005492	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
929102005493	dimer interface [polypeptide binding]; other site
929102005494	conserved gate region; other site
929102005495	putative PBP binding loops; other site
929102005496	ABC-ATPase subunit interface; other site
929102005497	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
929102005498	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
929102005499	Walker A/P-loop; other site
929102005500	ATP binding site [chemical binding]; other site
929102005501	Q-loop/lid; other site
929102005502	ABC transporter signature motif; other site
929102005503	Walker B; other site
929102005504	D-loop; other site
929102005505	H-loop/switch region; other site
929102005506	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
929102005507	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
929102005508	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
929102005509	Walker A/P-loop; other site
929102005510	ATP binding site [chemical binding]; other site
929102005511	Q-loop/lid; other site
929102005512	ABC transporter signature motif; other site
929102005513	Walker B; other site
929102005514	D-loop; other site
929102005515	H-loop/switch region; other site
929102005516	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
929102005517	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
929102005518	23S rRNA binding site [nucleotide binding]; other site
929102005519	L21 binding site [polypeptide binding]; other site
929102005520	L13 binding site [polypeptide binding]; other site
929102005521	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
929102005522	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
929102005523	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
929102005524	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
929102005525	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
929102005526	tRNA:m(5)U-54 methyltransferase; Region: gid_trmFO; TIGR00137
929102005527	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
929102005528	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4699
929102005529	Ribonuclease III family protein [Replication, recombination, and    repair]; Region: COG1939
929102005530	active site
929102005531	metal binding site [ion binding]; metal-binding site
929102005532	dimerization interface [polypeptide binding]; other site
929102005533	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
929102005534	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
929102005535	active site
929102005536	HIGH motif; other site
929102005537	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
929102005538	KMSKS motif; other site
929102005539	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
929102005540	tRNA binding surface [nucleotide binding]; other site
929102005541	anticodon binding site; other site
929102005542	Predicted integral membrane protein [Function unknown]; Region: COG3548
929102005543	Serine acetyltransferase [Amino acid transport and metabolism]; Region: CysE; COG1045
929102005544	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
929102005545	trimer interface [polypeptide binding]; other site
929102005546	active site
929102005547	substrate binding site [chemical binding]; other site
929102005548	CoA binding site [chemical binding]; other site
929102005549	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
929102005550	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
929102005551	RNase E interface [polypeptide binding]; other site
929102005552	trimer interface [polypeptide binding]; other site
929102005553	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
929102005554	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
929102005555	RNase E interface [polypeptide binding]; other site
929102005556	trimer interface [polypeptide binding]; other site
929102005557	active site
929102005558	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
929102005559	putative nucleic acid binding region [nucleotide binding]; other site
929102005560	G-X-X-G motif; other site
929102005561	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
929102005562	RNA binding site [nucleotide binding]; other site
929102005563	domain interface; other site
929102005564	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK02458
929102005565	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
929102005566	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
929102005567	active site
929102005568	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
929102005569	Ligand Binding Site [chemical binding]; other site
929102005570	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
929102005571	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
929102005572	catalytic residue [active]
929102005573	Putative amino acid metabolism; Region: DUF1831; pfam08866
929102005574	elongation factor Tu; Reviewed; Region: PRK00049
929102005575	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
929102005576	G1 box; other site
929102005577	GEF interaction site [polypeptide binding]; other site
929102005578	GTP/Mg2+ binding site [chemical binding]; other site
929102005579	Switch I region; other site
929102005580	G2 box; other site
929102005581	G3 box; other site
929102005582	Switch II region; other site
929102005583	G4 box; other site
929102005584	G5 box; other site
929102005585	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
929102005586	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
929102005587	Antibiotic Binding Site [chemical binding]; other site
929102005588	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
929102005589	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
929102005590	active site
929102005591	HIGH motif; other site
929102005592	nucleotide binding site [chemical binding]; other site
929102005593	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
929102005594	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
929102005595	active site
929102005596	KMSKS motif; other site
929102005597	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
929102005598	tRNA binding surface [nucleotide binding]; other site
929102005599	anticodon binding site; other site
929102005600	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
929102005601	DivIVA domain; Region: DivI1A_domain; TIGR03544
929102005602	Cell division initiation protein [Cell division and chromosome partitioning]; Region: DivIVA; COG3599
929102005603	Uncharacterized conserved protein, contains S4-like domain [Function unknown]; Region: COG2302
929102005604	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cl09940
929102005605	YGGT family; Region: YGGT; pfam02325
929102005606	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1799
929102005607	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
929102005608	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
929102005609	catalytic residue [active]
929102005610	cell division protein FtsZ; Validated; Region: PRK09330
929102005611	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
929102005612	nucleotide binding site [chemical binding]; other site
929102005613	SulA interaction site; other site
929102005614	Cell division ATPase FtsA [Cell division and chromosome partitioning]; Region: ftsA; COG0849
929102005615	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
929102005616	nucleotide binding site [chemical binding]; other site
929102005617	Cell division protein FtsA; Region: FtsA; pfam14450
929102005618	Domain of unknown function (DUF3484); Region: DUF3484; pfam11983
929102005619	EDD domain protein, DegV family; Region: DegV; TIGR00762
929102005620	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
929102005621	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
929102005622	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
929102005623	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
929102005624	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
929102005625	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
929102005626	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
929102005627	active site
929102005628	catalytic tetrad [active]
929102005629	Major Facilitator Superfamily; Region: MFS_1; pfam07690
929102005630	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929102005631	putative substrate translocation pore; other site
929102005632	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
929102005633	Helix-turn-helix domain; Region: HTH_38; pfam13936
929102005634	Integrase core domain; Region: rve; pfam00665
929102005635	Transcriptional regulator [Transcription]; Region: LysR; COG0583
929102005636	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
929102005637	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
929102005638	dimerization interface [polypeptide binding]; other site
929102005639	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
929102005640	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
929102005641	DNA binding residues [nucleotide binding]
929102005642	putative dimer interface [polypeptide binding]; other site
929102005643	Peptidase C1B subfamily (MEROPS database nomenclature); composed of eukaryotic bleomycin hydrolases (BH) and bacterial aminopeptidases C (pepC). The proteins of this subfamily contain a large insert relative to the C1A peptidase (papain) subfamily. BH is...; Region: Peptidase_C1B; cd00585
929102005644	trimer interface [polypeptide binding]; other site
929102005645	active site
929102005646	G bulge; other site
929102005647	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
929102005648	Zn2+ binding site [ion binding]; other site
929102005649	Mg2+ binding site [ion binding]; other site
929102005650	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
929102005651	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
929102005652	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
929102005653	dimer interface [polypeptide binding]; other site
929102005654	ADP-ribose binding site [chemical binding]; other site
929102005655	active site
929102005656	nudix motif; other site
929102005657	metal binding site [ion binding]; metal-binding site
929102005658	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14354
929102005659	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
929102005660	Substrate binding site; other site
929102005661	Mg++ binding site; other site
929102005662	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
929102005663	active site
929102005664	substrate binding site [chemical binding]; other site
929102005665	CoA binding site [chemical binding]; other site
929102005666	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
929102005667	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
929102005668	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
929102005669	16S/18S rRNA binding site [nucleotide binding]; other site
929102005670	S13e-L30e interaction site [polypeptide binding]; other site
929102005671	25S rRNA binding site [nucleotide binding]; other site
929102005672	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
929102005673	Catalytic domain of Protein Kinases; Region: PKc; cd00180
929102005674	active site
929102005675	ATP binding site [chemical binding]; other site
929102005676	substrate binding site [chemical binding]; other site
929102005677	activation loop (A-loop); other site
929102005678	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2815
929102005679	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
929102005680	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
929102005681	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
929102005682	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
929102005683	active site
929102005684	16S rRNA methyltransferase B; Provisional; Region: PRK14902
929102005685	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
929102005686	putative RNA binding site [nucleotide binding]; other site
929102005687	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929102005688	S-adenosylmethionine binding site [chemical binding]; other site
929102005689	Bacteriophage peptidoglycan hydrolase; Region: Amidase_5; pfam05382
929102005690	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
929102005691	holin, SPP1 family; Region: holin_SPP1; TIGR01592
929102005692	phage minor structural protein, N-terminal region; Region: put_anti_recept; TIGR01665
929102005693	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
929102005694	Peptidase family M23; Region: Peptidase_M23; pfam01551
929102005695	putative phage tail component, N-terminal domain; Region: phi3626_gp14_N; TIGR01633
929102005696	Phage-related protein [Function unknown]; Region: COG4722
929102005697	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
929102005698	Phage-related protein [Function unknown]; Region: COG5412
929102005699	Phage protein; Region: DUF3647; pfam12363
929102005700	phage major tail protein, TP901-1 family; Region: phgtail_TP901_1; TIGR02126
929102005701	phage protein, HK97 gp10 family; Region: phge_HK97_gp10; TIGR01725
929102005702	Phage gp6-like head-tail connector protein; Region: Phage_connect_1; pfam05135
929102005703	HeH/LEM domain; Region: HeH; pfam12949
929102005704	Phage capsid family; Region: Phage_capsid; pfam05065
929102005705	Domain of unknown function (DUF4355); Region: DUF4355; pfam14265
929102005706	phage putative head morphogenesis protein, SPP1 gp7 family; Region: phageSPP1_gp7; TIGR01641
929102005707	phage portal protein, SPP1 family; Region: portal_SPP1; TIGR01538
929102005708	Phage portal protein, SPP1 Gp6-like; Region: Phage_prot_Gp6; pfam05133
929102005709	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5410
929102005710	Terminase-like family; Region: Terminase_6; pfam03237
929102005711	Phage-related terminase [General function prediction only]; Region: COG5362; cl02216
929102005712	Terminase small subunit; Region: Terminase_2; cl01513
929102005713	Protein of unknown function (DUF722); Region: DUF722; pfam05263
929102005714	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
929102005715	trimer interface [polypeptide binding]; other site
929102005716	active site
929102005717	Protein of unknown function (DUF1642); Region: DUF1642; pfam07852
929102005718	Protein of unknown function (DUF1125); Region: DUF1125; pfam06563
929102005719	Protein of unknown function (DUF1031); Region: DUF1031; pfam06275
929102005720	Holliday junction resolvase [DNA replication, recombination, and repair]; Region: Rus; COG4570
929102005721	Primosomal protein DnaI N-terminus; Region: DnaI_N; pfam07319
929102005722	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929102005723	Walker A motif; other site
929102005724	ATP binding site [chemical binding]; other site
929102005725	Walker B motif; other site
929102005726	N-terminal phage replisome organiser (Phage_rep_org_N); Region: Phage_rep_org_N; pfam09681
929102005727	phage conserved hypothetical protein, C-terminal domain; Region: phg_TIGR02220
929102005728	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
929102005729	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
929102005730	dimer interface [polypeptide binding]; other site
929102005731	ssDNA binding site [nucleotide binding]; other site
929102005732	tetramer (dimer of dimers) interface [polypeptide binding]; other site
929102005733	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4712
929102005734	Bacteriophage Mu Gam like protein; Region: Phage_Mu_Gam; cl01825
929102005735	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929102005736	non-specific DNA binding site [nucleotide binding]; other site
929102005737	salt bridge; other site
929102005738	sequence-specific DNA binding site [nucleotide binding]; other site
929102005739	Protein of unknown function (DUF3892); Region: DUF3892; pfam13031
929102005740	Prophage antirepressor [Transcription]; Region: COG3617
929102005741	BRO family, N-terminal domain; Region: Bro-N; smart01040
929102005742	Phage antirepressor protein KilAC domain; Region: ANT; pfam03374
929102005743	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929102005744	non-specific DNA binding site [nucleotide binding]; other site
929102005745	salt bridge; other site
929102005746	sequence-specific DNA binding site [nucleotide binding]; other site
929102005747	putative transcription regulator; Region: PHA00212
929102005748	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929102005749	non-specific DNA binding site [nucleotide binding]; other site
929102005750	salt bridge; other site
929102005751	sequence-specific DNA binding site [nucleotide binding]; other site
929102005752	Domain of unknown function (DUF955); Region: DUF955; cl01076
929102005753	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
929102005754	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
929102005755	Int/Topo IB signature motif; other site
929102005756	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1302
929102005757	Predicted membrane protein [Function unknown]; Region: COG2261
929102005758	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
929102005759	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
929102005760	putative active site [active]
929102005761	substrate binding site [chemical binding]; other site
929102005762	putative cosubstrate binding site; other site
929102005763	catalytic site [active]
929102005764	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
929102005765	substrate binding site [chemical binding]; other site
929102005766	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
929102005767	dimer interface [polypeptide binding]; other site
929102005768	Contains a crystal structure of the Nudix hydrolase from Enterococcus faecalis, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_25; cd04684
929102005769	nudix motif; other site
929102005770	SnoaL-like domain; Region: SnoaL_2; pfam12680
929102005771	Primosomal protein N' (replication factor Y) - superfamily II helicase [DNA replication, recombination, and repair]; Region: PriA; COG1198
929102005772	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
929102005773	ATP binding site [chemical binding]; other site
929102005774	putative Mg++ binding site [ion binding]; other site
929102005775	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
929102005776	nucleotide binding region [chemical binding]; other site
929102005777	ATP-binding site [chemical binding]; other site
929102005778	DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392
929102005779	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
929102005780	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
929102005781	catalytic site [active]
929102005782	G-X2-G-X-G-K; other site
929102005783	phosphodiesterase; Provisional; Region: PRK12704
929102005784	The band 7 domain of flotillin (reggie) like proteins. This group contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual proteins of this...; Region: Band_7; cl02525
929102005785	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
929102005786	Zn2+ binding site [ion binding]; other site
929102005787	Mg2+ binding site [ion binding]; other site
929102005788	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
929102005789	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
929102005790	active site
929102005791	trimer interface [polypeptide binding]; other site
929102005792	allosteric site; other site
929102005793	active site lid [active]
929102005794	hexamer (dimer of trimers) interface [polypeptide binding]; other site
929102005795	S-adenosylmethionine synthetase; Validated; Region: PRK05250
929102005796	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
929102005797	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
929102005798	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
929102005799	Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane]; Region: Cfa; COG2230
929102005800	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929102005801	S-adenosylmethionine binding site [chemical binding]; other site
929102005802	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
929102005803	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
929102005804	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
929102005805	Putative stress-responsive transcriptional regulator [Transcription / Signal transduction mechanisms]; Region: PspC; COG1983
929102005806	Putative stress-responsive transcriptional regulator [Transcription / Signal transduction mechanisms]; Region: PspC; COG1983
929102005807	Uncharacterized conserved protein [Function unknown]; Region: COG3595
929102005808	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
929102005809	N-acetylmuramoyl-L-alanine amidase; Validated; Region: PRK08581
929102005810	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
929102005811	CHAP domain; Region: CHAP; pfam05257
929102005812	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
929102005813	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
929102005814	intersubunit interface [polypeptide binding]; other site
929102005815	active site
929102005816	zinc binding site [ion binding]; other site
929102005817	Na+ binding site [ion binding]; other site
929102005818	Predicted membrane protein [Function unknown]; Region: COG2860
929102005819	UPF0126 domain; Region: UPF0126; pfam03458
929102005820	UPF0126 domain; Region: UPF0126; pfam03458
929102005821	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
929102005822	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
929102005823	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
929102005824	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
929102005825	active site
929102005826	dimer interface [polypeptide binding]; other site
929102005827	motif 1; other site
929102005828	motif 2; other site
929102005829	motif 3; other site
929102005830	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
929102005831	anticodon binding site; other site
929102005832	ATP cone domain; Region: ATP-cone; pfam03477
929102005833	Nitroreductase-like family 4.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_4; cd02140
929102005834	dimer interface [polypeptide binding]; other site
929102005835	FMN binding site [chemical binding]; other site
929102005836	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
929102005837	active site
929102005838	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
929102005839	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
929102005840	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
929102005841	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
929102005842	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929102005843	homodimer interface [polypeptide binding]; other site
929102005844	catalytic residue [active]
929102005845	cystathionine gamma-synthase; Reviewed; Region: PRK07269
929102005846	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
929102005847	homodimer interface [polypeptide binding]; other site
929102005848	substrate-cofactor binding pocket; other site
929102005849	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929102005850	catalytic residue [active]
929102005851	Homoserine trans-succinylase [Amino acid transport and metabolism]; Region: MetA; COG1897
929102005852	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
929102005853	proposed active site lysine [active]
929102005854	conserved cys residue [active]
929102005855	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity. They also contain a...; Region: Nudix_Hydrolase_1; cd03674
929102005856	nudix motif; other site
929102005857	Aldose 1-epimerase, similar to Lactococcus lactis lacX; Region: Aldose_epim_lacX; cd09024
929102005858	active site
929102005859	catalytic residues [active]
929102005860	Predicted HD-superfamily hydrolase [General function prediction only]; Region: COG3481
929102005861	YhaM_OBF_like: A subfamily of OB folds similar to that found in Bacillus subtilis YhaM and Staphylococcus aureus cmp-binding factor-1 (SaCBF1). Both these proteins are 3'-to-5'exoribonucleases. YhaM requires Mn2+ or Co2+ for activity and is...; Region: YhaM_OBF_like; cd04492
929102005862	generic binding surface II; other site
929102005863	generic binding surface I; other site
929102005864	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
929102005865	Zn2+ binding site [ion binding]; other site
929102005866	Mg2+ binding site [ion binding]; other site
929102005867	Predicted nuclease of restriction endonuclease-like fold, RmuC family [General function prediction only]; Region: COG1322
929102005868	RmuC family; Region: RmuC; pfam02646
929102005869	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
929102005870	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
929102005871	substrate binding site [chemical binding]; other site
929102005872	hexamer interface [polypeptide binding]; other site
929102005873	metal binding site [ion binding]; metal-binding site
929102005874	GTPase RsgA; Reviewed; Region: PRK00098
929102005875	S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466
929102005876	RNA binding site [nucleotide binding]; other site
929102005877	homodimer interface [polypeptide binding]; other site
929102005878	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
929102005879	GTPase/Zn-binding domain interface [polypeptide binding]; other site
929102005880	GTP/Mg2+ binding site [chemical binding]; other site
929102005881	G4 box; other site
929102005882	G1 box; other site
929102005883	Switch I region; other site
929102005884	G2 box; other site
929102005885	G3 box; other site
929102005886	Switch II region; other site
929102005887	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883
929102005888	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3584
929102005889	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
929102005890	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
929102005891	putative tRNA-binding site [nucleotide binding]; other site
929102005892	B3/4 domain; Region: B3_4; pfam03483
929102005893	tRNA synthetase B5 domain; Region: B5; smart00874
929102005894	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
929102005895	dimer interface [polypeptide binding]; other site
929102005896	motif 1; other site
929102005897	motif 3; other site
929102005898	motif 2; other site
929102005899	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
929102005900	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
929102005901	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
929102005902	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
929102005903	dimer interface [polypeptide binding]; other site
929102005904	motif 1; other site
929102005905	active site
929102005906	motif 2; other site
929102005907	motif 3; other site
929102005908	Phenolic acid decarboxylase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3479
929102005909	Predicted transcriptional regulators [Transcription]; Region: COG1695
929102005910	Transcriptional regulator PadR-like family; Region: PadR; cl17335
929102005911	Virulence activator alpha C-term; Region: Vir_act_alpha_C; pfam10400
929102005912	GH18 domain of Chitinase D (ChiD).  ChiD, a chitinase found in Bacillus circulans, hydrolyzes the 1,4-beta-linkages of N-acetylglucosamine in chitin and chitodextrins.  The domain architecture of ChiD includes a catalytic glycosyl hydrolase family 18; Region: GH18_chitinase_D-like; cd02871
929102005913	Glycosyl hydrolases family 18; Region: Glyco_hydro_18; pfam00704
929102005914	putative active site [active]
929102005915	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
929102005916	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
929102005917	aromatic chitin/cellulose binding site residues [chemical binding]; other site
929102005918	Chitin binding domain; Region: Chitin_bind_3; pfam03067
929102005919	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
929102005920	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
929102005921	GDP-binding site [chemical binding]; other site
929102005922	ACT binding site; other site
929102005923	IMP binding site; other site
929102005924	Predicted permease, cadmium resistance protein [Inorganic ion transport and metabolism]; Region: CadD; COG4300
929102005925	Cadmium resistance transporter; Region: Cad; pfam03596
929102005926	Predicted flavin-nucleotide-binding protein [General function prediction only]; Region: COG3467
929102005927	Uncharacterized conserved protein [Function unknown]; Region: COG5646
929102005928	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
929102005929	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
929102005930	dimerization interface [polypeptide binding]; other site
929102005931	domain crossover interface; other site
929102005932	redox-dependent activation switch; other site
929102005933	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
929102005934	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cl17426
929102005935	NADP+ binding site [chemical binding]; other site
929102005936	folate binding site [chemical binding]; other site
929102005937	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
929102005938	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
929102005939	FMN binding site [chemical binding]; other site
929102005940	active site
929102005941	catalytic residues [active]
929102005942	substrate binding site [chemical binding]; other site
929102005943	Uncharacterized conserved protein [Function unknown]; Region: COG1284
929102005944	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
929102005945	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
929102005946	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
929102005947	Uncharacterized conserved protein [Function unknown]; Region: COG1284
929102005948	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
929102005949	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
929102005950	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
929102005951	Uncharacterized conserved protein [Function unknown]; Region: COG1284
929102005952	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
929102005953	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
929102005954	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
929102005955	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
929102005956	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
929102005957	dimer interface [polypeptide binding]; other site
929102005958	anticodon binding site; other site
929102005959	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
929102005960	homodimer interface [polypeptide binding]; other site
929102005961	motif 1; other site
929102005962	active site
929102005963	motif 2; other site
929102005964	GAD domain; Region: GAD; pfam02938
929102005965	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
929102005966	active site
929102005967	motif 3; other site
929102005968	histidyl-tRNA synthetase; Region: hisS; TIGR00442
929102005969	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
929102005970	dimer interface [polypeptide binding]; other site
929102005971	motif 1; other site
929102005972	active site
929102005973	motif 2; other site
929102005974	motif 3; other site
929102005975	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
929102005976	anticodon binding site; other site
929102005977	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929102005978	non-specific DNA binding site [nucleotide binding]; other site
929102005979	salt bridge; other site
929102005980	sequence-specific DNA binding site [nucleotide binding]; other site
929102005981	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
929102005982	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
929102005983	Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown]; Region: COG1426
929102005984	Helix-turn-helix domain; Region: HTH_25; pfam13413
929102005985	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
929102005986	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
929102005987	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
929102005988	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
929102005989	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
929102005990	S4-like RNA binding protein [Replication, recombination, and repair]; Region: COG2501
929102005991	recF protein; Region: recf; TIGR00611
929102005992	ATP-binding cassette domain of RecF; Region: ABC_RecF; cd03242
929102005993	Walker A/P-loop; other site
929102005994	ATP binding site [chemical binding]; other site
929102005995	Q-loop/lid; other site
929102005996	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929102005997	ABC transporter signature motif; other site
929102005998	Walker B; other site
929102005999	D-loop; other site
929102006000	H-loop/switch region; other site
929102006001	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
929102006002	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
929102006003	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
929102006004	DNA binding residues [nucleotide binding]
929102006005	putative dimer interface [polypeptide binding]; other site
929102006006	Uncharacterized protein with an alpha/beta hydrolase fold [General function prediction only]; Region: COG4814
929102006007	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
929102006008	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
929102006009	NAD binding site [chemical binding]; other site
929102006010	homodimer interface [polypeptide binding]; other site
929102006011	active site
929102006012	substrate binding site [chemical binding]; other site
929102006013	beta-D-galactosidase; Reviewed; Region: lacZ; PRK09525
929102006014	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
929102006015	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
929102006016	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
929102006017	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
929102006018	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK05270
929102006019	Galactose-1-phosphate uridyl transferase, N-terminal domain; Region: GalP_UDP_transf; pfam01087
929102006020	Galactose-1-phosphate uridyl transferase, C-terminal domain; Region: GalP_UDP_tr_C; pfam02744
929102006021	galactokinase; Provisional; Region: PRK05322
929102006022	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
929102006023	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
929102006024	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
929102006025	active site
929102006026	catalytic residues [active]
929102006027	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
929102006028	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929102006029	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
929102006030	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
929102006031	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
929102006032	putative active site [active]
929102006033	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
929102006034	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
929102006035	active site
929102006036	catalytic tetrad [active]
929102006037	nicotinamide-nucleotide adenylyltransferase, NadR type; Region: nadR_NMN_Atrans; TIGR01526
929102006038	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional NadR-like proteins; Region: NMNAT_NadR; cd02167
929102006039	active site
929102006040	(T/H)XGH motif; other site
929102006041	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
929102006042	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
929102006043	Putative D-isomer specific 2-hydroxyacid dehydrogenase; Region: 2-Hacid_dh_1; cd05300
929102006044	NAD binding site [chemical binding]; other site
929102006045	ligand binding site [chemical binding]; other site
929102006046	catalytic site [active]
929102006047	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
929102006048	Peptidase family U32; Region: Peptidase_U32; pfam01136
929102006049	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
929102006050	Peptidase family U32; Region: Peptidase_U32; pfam01136
929102006051	Protein of unknown function (DUF3270); Region: DUF3270; pfam11674
929102006052	Methyltransferase domain; Region: Methyltransf_31; pfam13847
929102006053	Methyltransferase domain; Region: Methyltransf_11; pfam08241
929102006054	S-adenosylmethionine binding site [chemical binding]; other site
929102006055	CutC family; Region: CutC; pfam03932
929102006056	Predicted ABC-type exoprotein transport system, permease component [Intracellular trafficking and secretion]; Region: EcsB; COG4473
929102006057	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
929102006058	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
929102006059	Walker A/P-loop; other site
929102006060	ATP binding site [chemical binding]; other site
929102006061	Q-loop/lid; other site
929102006062	ABC transporter signature motif; other site
929102006063	Walker B; other site
929102006064	D-loop; other site
929102006065	H-loop/switch region; other site
929102006066	Membrane domain of membrane-anchored glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: COG4781
929102006067	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
929102006068	Glycerophosphodiester phosphodiesterase domain of uncharacterized bacterial glycerophosphodiester phosphodiesterases; Region: GDPD_memb_like; cd08579
929102006069	putative active site [active]
929102006070	catalytic site [active]
929102006071	putative metal binding site [ion binding]; other site
929102006072	HINT (histidine triad nucleotide-binding protein) subgroup: Members of this CD belong to the superfamily of histidine triad hydrolases that act on alpha-phosphate of ribonucleotides. This subgroup includes members from all three forms of cellular life; Region: HINT_subgroup; cd01277
929102006073	HIT family signature motif; other site
929102006074	catalytic residue [active]
929102006075	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
929102006076	mRNA/rRNA interface [nucleotide binding]; other site
929102006077	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
929102006078	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
929102006079	23S rRNA interface [nucleotide binding]; other site
929102006080	L7/L12 interface [polypeptide binding]; other site
929102006081	putative thiostrepton binding site; other site
929102006082	L25 interface [polypeptide binding]; other site
929102006083	heavy metal translocating P-type ATPase; Region: ATPase-IB_hvy; TIGR01525
929102006084	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
929102006085	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
929102006086	motif II; other site
929102006087	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
929102006088	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
929102006089	ligand binding site [chemical binding]; other site
929102006090	flexible hinge region; other site
929102006091	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
929102006092	putative switch regulator; other site
929102006093	non-specific DNA interactions [nucleotide binding]; other site
929102006094	DNA binding site [nucleotide binding]
929102006095	sequence specific DNA binding site [nucleotide binding]; other site
929102006096	putative cAMP binding site [chemical binding]; other site
929102006097	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4479
929102006098	methionine sulfoxide reductase A; Provisional; Region: PRK14054
929102006099	Predicted RNA-bindining protein (contains S1 and HTH domains) [General function prediction only]; Region: COG2996
929102006100	S1 domain; Region: S1_2; pfam13509
929102006101	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
929102006102	RNA binding site [nucleotide binding]; other site
929102006103	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
929102006104	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929102006105	Coenzyme A binding pocket [chemical binding]; other site
929102006106	ribosome recycling factor; Reviewed; Region: frr; PRK00083
929102006107	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
929102006108	hinge region; other site
929102006109	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
929102006110	putative nucleotide binding site [chemical binding]; other site
929102006111	uridine monophosphate binding site [chemical binding]; other site
929102006112	homohexameric interface [polypeptide binding]; other site
929102006113	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
929102006114	propionate/acetate kinase; Provisional; Region: PRK12379
929102006115	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
929102006116	propionate/acetate kinase; Provisional; Region: PRK12379
929102006117	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827
929102006118	Methyltransferase domain; Region: Methyltransf_26; pfam13659
929102006119	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
929102006120	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
929102006121	G1 box; other site
929102006122	putative GEF interaction site [polypeptide binding]; other site
929102006123	GTP/Mg2+ binding site [chemical binding]; other site
929102006124	Switch I region; other site
929102006125	G2 box; other site
929102006126	G3 box; other site
929102006127	Switch II region; other site
929102006128	G4 box; other site
929102006129	G5 box; other site
929102006130	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
929102006131	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
929102006132	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929102006133	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
929102006134	Walker A/P-loop; other site
929102006135	ATP binding site [chemical binding]; other site
929102006136	Q-loop/lid; other site
929102006137	ABC transporter signature motif; other site
929102006138	Walker B; other site
929102006139	D-loop; other site
929102006140	H-loop/switch region; other site
929102006141	Bacteriocin (Lactococcin_972); Region: Lactococcin_972; cl09891
929102006142	LytTr DNA-binding domain; Region: LytTR; pfam04397
929102006143	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4483
929102006144	ROK family protein (putative glucokinase); Region: ROK_glcA_fam; TIGR00744
929102006145	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
929102006146	nucleotide binding site [chemical binding]; other site
929102006147	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
929102006148	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
929102006149	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
929102006150	dimerization interface [polypeptide binding]; other site
929102006151	DPS ferroxidase diiron center [ion binding]; other site
929102006152	ion pore; other site
929102006153	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
929102006154	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
929102006155	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
929102006156	active site
929102006157	DNA polymerase IV; Validated; Region: PRK02406
929102006158	DNA binding site [nucleotide binding]
929102006159	This CD includes bacterial (Agrobacterium tumefaciens and Caulobacter crescentus ProX, and Clostridium sticklandii PrdX) and eukaryotic (Plasmodium falciparum N-terminal ProRS editing domain) sequences. The C. sticklandii PrdX protein, a homolog of the...; Region: PrdX_deacylase; cd04335
929102006160	putative deacylase active site [active]
929102006161	arginine-ornithine antiporter; Region: arg_ornith_anti; TIGR03810
929102006162	transaminase; Validated; Region: PRK07324
929102006163	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
929102006164	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929102006165	homodimer interface [polypeptide binding]; other site
929102006166	catalytic residue [active]
929102006167	carbamate kinase; Reviewed; Region: PRK12686
929102006168	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
929102006169	putative substrate binding site [chemical binding]; other site
929102006170	nucleotide binding site [chemical binding]; other site
929102006171	nucleotide binding site [chemical binding]; other site
929102006172	homodimer interface [polypeptide binding]; other site
929102006173	carbamate kinase; Reviewed; Region: PRK12686
929102006174	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
929102006175	putative substrate binding site [chemical binding]; other site
929102006176	nucleotide binding site [chemical binding]; other site
929102006177	nucleotide binding site [chemical binding]; other site
929102006178	homodimer interface [polypeptide binding]; other site
929102006179	arginine-ornithine antiporter; Region: arg_ornith_anti; TIGR03810
929102006180	ornithine carbamoyltransferase; Validated; Region: PRK02102
929102006181	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
929102006182	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
929102006183	arginine deiminase; Provisional; Region: PRK01388
929102006184	arginyl-tRNA synthetase; Reviewed; Region: PRK12451
929102006185	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
929102006186	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
929102006187	active site
929102006188	HIGH motif; other site
929102006189	KMSK motif region; other site
929102006190	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
929102006191	tRNA binding surface [nucleotide binding]; other site
929102006192	anticodon binding site; other site
929102006193	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
929102006194	arginine repressor; Region: argR_whole; TIGR01529
929102006195	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
929102006196	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
929102006197	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
929102006198	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
929102006199	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
929102006200	SWIM zinc finger; Region: SWIM; pfam04434
929102006201	Bacterial SNF2 helicase associated; Region: SNF2_assoc; pfam08455
929102006202	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
929102006203	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
929102006204	ATP binding site [chemical binding]; other site
929102006205	putative Mg++ binding site [ion binding]; other site
929102006206	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
929102006207	nucleotide binding region [chemical binding]; other site
929102006208	ATP-binding site [chemical binding]; other site
929102006209	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
929102006210	metal ion-dependent adhesion site (MIDAS); other site
929102006211	Repeat unit of collagen-binding protein domain B; Region: CollagenBindB; cd00222
929102006212	domain interaction interfaces [polypeptide binding]; other site
929102006213	Cna protein B-type domain; Region: Cna_B; pfam05738
929102006214	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
929102006215	pyruvate oxidase; Region: pyruv_oxi_spxB; TIGR02720
929102006216	PYR/PP interface [polypeptide binding]; other site
929102006217	dimer interface [polypeptide binding]; other site
929102006218	tetramer interface [polypeptide binding]; other site
929102006219	TPP binding site [chemical binding]; other site
929102006220	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
929102006221	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
929102006222	TPP-binding site [chemical binding]; other site
929102006223	Beta-lactamase; Region: Beta-lactamase; pfam00144
929102006224	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
929102006225	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
929102006226	CAAX protease self-immunity; Region: Abi; pfam02517
929102006227	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
929102006228	amphipathic channel; other site
929102006229	Asn-Pro-Ala signature motifs; other site
929102006230	x-prolyl-dipeptidyl aminopeptidase; Provisional; Region: PRK05371
929102006231	X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal; Region: PepX_N; smart00940
929102006232	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
929102006233	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; pfam08530
929102006234	Predicted glutamine amidotransferases [General function prediction only]; Region: COG2071
929102006235	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
929102006236	catalytic triad [active]
929102006237	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
929102006238	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
929102006239	substrate binding pocket [chemical binding]; other site
929102006240	membrane-bound complex binding site; other site
929102006241	hinge residues; other site
929102006242	pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK07251
929102006243	TrkA-N domain; Region: TrkA_N; pfam02254
929102006244	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
929102006245	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
929102006246	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
929102006247	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
929102006248	active site
929102006249	HIGH motif; other site
929102006250	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
929102006251	active site
929102006252	KMSKS motif; other site
929102006253	Nicotinamidase_ related amidohydrolases.  Cysteine hydrolases of unknown function that share the catalytic triad with other amidohydrolases, like nicotinamidase, which converts nicotinamide to nicotinic acid and ammonia; Region: nicotinamidase_related; cd01014
929102006254	Isochorismatase family; Region: Isochorismatase; pfam00857
929102006255	catalytic triad [active]
929102006256	conserved cis-peptide bond; other site
929102006257	PAP2_like_6 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which mainly contains bacterial proteins, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_6; cd03396
929102006258	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
929102006259	active site
929102006260	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
929102006261	DNA-binding ferritin-like protein (Dps family) [General function prediction only]; Region: COG4817
929102006262	DNA-binding ferritin-like protein (Dps family) [General function prediction only]; Region: COG4817
929102006263	Predicted transcriptional regulators [Transcription]; Region: COG1695
929102006264	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
929102006265	Integral membrane protein (PIN domain superfamily) [General function prediction only]; Region: COG4956
929102006266	PIN domain of Thermus Thermophilus Hb8, uncharacterized Bacillus subtilis YacL, and other bacterial homologs; Region: PIN_YacL; cd09877
929102006267	putative active site [active]
929102006268	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
929102006269	Helix-turn-helix domain; Region: HTH_38; pfam13936
929102006270	Integrase core domain; Region: rve; pfam00665
929102006271	Predicted membrane protein [Function unknown]; Region: COG3619
929102006272	DNA repair protein RadA; Provisional; Region: PRK11823
929102006273	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
929102006274	Walker A motif/ATP binding site; other site
929102006275	ATP binding site [chemical binding]; other site
929102006276	Walker B motif; other site
929102006277	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
929102006278	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
929102006279	metal-binding site [ion binding]
929102006280	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
929102006281	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
929102006282	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
929102006283	alphaNTD homodimer interface [polypeptide binding]; other site
929102006284	alphaNTD - beta interaction site [polypeptide binding]; other site
929102006285	alphaNTD - beta' interaction site [polypeptide binding]; other site
929102006286	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
929102006287	30S ribosomal protein S11; Validated; Region: PRK05309
929102006288	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
929102006289	30S ribosomal protein S13; Region: bact_S13; TIGR03631
929102006290	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
929102006291	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
929102006292	rRNA binding site [nucleotide binding]; other site
929102006293	predicted 30S ribosome binding site; other site
929102006294	adenylate kinase; Reviewed; Region: adk; PRK00279
929102006295	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
929102006296	AMP-binding site [chemical binding]; other site
929102006297	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
929102006298	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
929102006299	SecY translocase; Region: SecY; pfam00344
929102006300	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
929102006301	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
929102006302	23S rRNA binding site [nucleotide binding]; other site
929102006303	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
929102006304	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
929102006305	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
929102006306	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
929102006307	5S rRNA interface [nucleotide binding]; other site
929102006308	L27 interface [polypeptide binding]; other site
929102006309	23S rRNA interface [nucleotide binding]; other site
929102006310	L5 interface [polypeptide binding]; other site
929102006311	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
929102006312	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
929102006313	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
929102006314	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
929102006315	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08061
929102006316	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
929102006317	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
929102006318	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
929102006319	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
929102006320	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
929102006321	RNA binding site [nucleotide binding]; other site
929102006322	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
929102006323	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
929102006324	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
929102006325	23S rRNA interface [nucleotide binding]; other site
929102006326	putative translocon interaction site; other site
929102006327	signal recognition particle (SRP54) interaction site; other site
929102006328	L23 interface [polypeptide binding]; other site
929102006329	trigger factor interaction site; other site
929102006330	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
929102006331	23S rRNA interface [nucleotide binding]; other site
929102006332	5S rRNA interface [nucleotide binding]; other site
929102006333	putative antibiotic binding site [chemical binding]; other site
929102006334	L25 interface [polypeptide binding]; other site
929102006335	L27 interface [polypeptide binding]; other site
929102006336	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
929102006337	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
929102006338	G-X-X-G motif; other site
929102006339	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
929102006340	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
929102006341	putative translocon binding site; other site
929102006342	protein-rRNA interface [nucleotide binding]; other site
929102006343	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
929102006344	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
929102006345	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
929102006346	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
929102006347	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
929102006348	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
929102006349	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
929102006350	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
929102006351	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
929102006352	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
929102006353	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
929102006354	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
929102006355	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
929102006356	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
929102006357	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929102006358	catalytic residue [active]
929102006359	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
929102006360	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
929102006361	putative homodimer interface [polypeptide binding]; other site
929102006362	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
929102006363	heterodimer interface [polypeptide binding]; other site
929102006364	homodimer interface [polypeptide binding]; other site
929102006365	Preprotein translocase subunit SecE [Intracellular trafficking and secretion]; Region: SecE; COG0690
929102006366	50S ribosomal protein L33; Validated; Region: rpmG; PRK00504
929102006367	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
929102006368	yrhL-like subfamily of SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_yrhL_like; cd01840
929102006369	catalytic triad [active]
929102006370	catalytic triad [active]
929102006371	oxyanion hole [active]
929102006372	Transglycosylase; Region: Transgly; pfam00912
929102006373	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
929102006374	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
929102006375	Predicted membrane protein [Function unknown]; Region: COG2323
929102006376	Protein of unknown function (DUF3290); Region: DUF3290; pfam11694
929102006377	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
929102006378	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
929102006379	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
929102006380	active site
929102006381	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
929102006382	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
929102006383	ABC-ATPase subunit  interface; other site
929102006384	dimer interface [polypeptide binding]; other site
929102006385	putative PBP binding regions; other site
929102006386	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
929102006387	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
929102006388	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
929102006389	Metal binding protein AcdA.  These proteins have been shown to function in the ABC uptake of Zn2+ and Mn2+ and in competence for genetic transformation and adhesion. The AcdA proteins belong to the TroA superfamily of helical backbone metal receptor...; Region: AdcA; cd01017
929102006390	metal binding site [ion binding]; metal-binding site
929102006391	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
929102006392	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
929102006393	putative DNA binding site [nucleotide binding]; other site
929102006394	putative Zn2+ binding site [ion binding]; other site
929102006395	Competence protein ComGF [Intracellular trafficking and secretion]; Region: ComGF; COG4940
929102006396	Type II secretory pathway pseudopilin; Region: PulG; pfam11773
929102006397	Competence protein ComGC [Intracellular trafficking and secretion]; Region: ComGC; COG4537
929102006398	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929102006399	Coenzyme A binding pocket [chemical binding]; other site
929102006400	Bacteriophage peptidoglycan hydrolase; Region: Amidase_5; pfam05382
929102006401	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
929102006402	Phage lysis protein, holin; Region: Phage_holin; pfam04688
929102006403	Prophage endopeptidase tail; Region: Prophage_tail; cl12123
929102006404	Phage tail protein; Region: Sipho_tail; pfam05709
929102006405	Phage tail protein; Region: Sipho_tail; cl17486
929102006406	Phage-related protein [Function unknown]; Region: COG5412
929102006407	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
929102006408	Bacteriophage Gp15 protein; Region: Phage_Gp15; pfam06854
929102006409	PAS fold; Region: PAS_7; pfam12860
929102006410	Minor capsid protein from bacteriophage; Region: Minor_capsid_3; pfam12691
929102006411	Minor capsid protein; Region: Minor_capsid_1; pfam10665
929102006412	Head-Tail Connector Proteins gp6 and gp15, and similar proteins; Region: gp6_gp15_like; cl12049
929102006413	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
929102006414	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
929102006415	Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072
929102006416	Phage-related protein [Function unknown]; Region: COG4695; cl01923
929102006417	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5410
929102006418	Terminase-like family; Region: Terminase_6; pfam03237
929102006419	Phage-related terminase [General function prediction only]; Region: COG5362; cl02216
929102006420	Protein of unknown function (DUF722); Region: DUF722; pfam05263
929102006421	Protein of unknown function (DUF1140); Region: DUF1140; pfam06600
929102006422	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cl00279
929102006423	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
929102006424	trimer interface [polypeptide binding]; other site
929102006425	active site
929102006426	Protein of unknown function (DUF1642); Region: DUF1642; pfam07852
929102006427	Endodeoxyribonuclease RusA; Region: RusA; pfam05866
929102006428	L-rhamnose isomerase; Provisional; Region: PRK01076
929102006429	N-terminal phage replisome organiser (Phage_rep_org_N); Region: Phage_rep_org_N; cl09889
929102006430	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
929102006431	RecT family; Region: RecT; pfam03837
929102006432	Herpesvirus UL25 family; Region: Herpes_UL25; pfam01499
929102006433	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
929102006434	ORF6C domain; Region: ORF6C; pfam10552
929102006435	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
929102006436	non-specific DNA binding site [nucleotide binding]; other site
929102006437	salt bridge; other site
929102006438	sequence-specific DNA binding site [nucleotide binding]; other site
929102006439	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
929102006440	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929102006441	non-specific DNA binding site [nucleotide binding]; other site
929102006442	salt bridge; other site
929102006443	sequence-specific DNA binding site [nucleotide binding]; other site
929102006444	Pleckstrin homology-like domain; Region: PH-like; cl17171
929102006445	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
929102006446	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
929102006447	catalytic residues [active]
929102006448	catalytic nucleophile [active]
929102006449	Presynaptic Site I dimer interface [polypeptide binding]; other site
929102006450	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
929102006451	Synaptic Flat tetramer interface [polypeptide binding]; other site
929102006452	Synaptic Site I dimer interface [polypeptide binding]; other site
929102006453	DNA binding site [nucleotide binding]
929102006454	Recombinase; Region: Recombinase; pfam07508
929102006455	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
929102006456	Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459
929102006457	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
929102006458	Type II/IV secretion system protein; Region: T2SE; pfam00437
929102006459	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
929102006460	Walker A motif; other site
929102006461	ATP binding site [chemical binding]; other site
929102006462	Walker B motif; other site
929102006463	DNA polymerase III polC-type N-terminus; Region: DNA_pol3_alph_N; pfam11490
929102006464	polC_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold nucleic acid binding domain of Bacillus subtilis type C replicative DNA polymerase III alpha subunit (polC). Replication in B. subtilis and Staphylococcus aureus requires two...; Region: polC_OBF; cd04484
929102006465	generic binding surface II; other site
929102006466	generic binding surface I; other site
929102006467	DNA polymerase III, alpha chain, Gram-positive type; Region: polC_Gram_pos; TIGR01405
929102006468	polC_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold nucleic acid binding domain of Bacillus subtilis type C replicative DNA polymerase III alpha subunit (polC). Replication in B. subtilis and Staphylococcus aureus requires two...; Region: polC_OBF; cd04484
929102006469	generic binding surface II; other site
929102006470	generic binding surface I; other site
929102006471	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
929102006472	active site
929102006473	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
929102006474	active site
929102006475	catalytic site [active]
929102006476	substrate binding site [chemical binding]; other site
929102006477	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III at PolC gene; Region: PHP_PolIIIA_POLC; cd07435
929102006478	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
929102006479	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
929102006480	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
929102006481	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
929102006482	prolyl-tRNA synthetase; Provisional; Region: PRK09194
929102006483	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
929102006484	dimer interface [polypeptide binding]; other site
929102006485	motif 1; other site
929102006486	active site
929102006487	motif 2; other site
929102006488	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
929102006489	putative deacylase active site [active]
929102006490	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
929102006491	active site
929102006492	motif 3; other site
929102006493	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
929102006494	anticodon binding site; other site
929102006495	RIP metalloprotease RseP; Region: TIGR00054
929102006496	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
929102006497	active site
929102006498	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
929102006499	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
929102006500	protein binding site [polypeptide binding]; other site
929102006501	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
929102006502	putative substrate binding region [chemical binding]; other site
929102006503	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
929102006504	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
929102006505	undecaprenyl pyrophosphate synthase; Provisional; Region: PRK14830
929102006506	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
929102006507	catalytic residue [active]
929102006508	putative FPP diphosphate  binding site; other site
929102006509	putative FPP binding hydrophobic cleft; other site
929102006510	dimer interface [polypeptide binding]; other site
929102006511	putative IPP diphosphate binding site; other site
929102006512	Preprotein translocase subunit; Region: YajC; cl00806
929102006513	DNA alkylation repair enzyme; Region: DNA_alkylation; pfam08713
929102006514	A new structural DNA glycosylase containing HEAT-like repeats; Region: AlkD_like_1; cd07064
929102006515	active site
929102006516	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
929102006517	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
929102006518	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
929102006519	protein binding site [polypeptide binding]; other site
929102006520	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
929102006521	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
929102006522	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
929102006523	This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1; Region: GT1_UGDG_like; cd03817
929102006524	putative ADP-binding pocket [chemical binding]; other site
929102006525	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4703
929102006526	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
929102006527	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929102006528	S-adenosylmethionine binding site [chemical binding]; other site
929102006529	DNA polymerase I; Provisional; Region: PRK05755
929102006530	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
929102006531	active site
929102006532	metal binding site 1 [ion binding]; metal-binding site
929102006533	putative 5' ssDNA interaction site; other site
929102006534	metal binding site 3; metal-binding site
929102006535	metal binding site 2 [ion binding]; metal-binding site
929102006536	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
929102006537	putative DNA binding site [nucleotide binding]; other site
929102006538	putative metal binding site [ion binding]; other site
929102006539	inactive DEDDy 3'-5' exonuclease domain of Bacillus stearothermophilus DNA polymerase I and similar family-A DNA polymerases; Region: DNA_polA_I_Bacillus_like_exo; cd06140
929102006540	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
929102006541	active site
929102006542	DNA binding site [nucleotide binding]
929102006543	catalytic site [active]
929102006544	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
929102006545	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
929102006546	motif I; other site
929102006547	active site
929102006548	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
929102006549	Transcriptional regulators [Transcription]; Region: PurR; COG1609
929102006550	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
929102006551	DNA binding site [nucleotide binding]
929102006552	domain linker motif; other site
929102006553	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
929102006554	Negative regulator of septation ring formation [Cell division and chromosome partitioning]; Region: EzrA; COG4477
929102006555	elongation factor Ts; Provisional; Region: tsf; PRK09377
929102006556	UBA/TS-N domain; Region: UBA; pfam00627
929102006557	Elongation factor TS; Region: EF_TS; pfam00889
929102006558	Elongation factor TS; Region: EF_TS; pfam00889
929102006559	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
929102006560	rRNA interaction site [nucleotide binding]; other site
929102006561	S8 interaction site; other site
929102006562	putative laminin-1 binding site; other site
929102006563	3-carboxymuconate cyclase [Carbohydrate transport and metabolism]; Region: COG2706
929102006564	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
929102006565	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
929102006566	putative catalytic cysteine [active]
929102006567	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
929102006568	putative active site [active]
929102006569	metal binding site [ion binding]; metal-binding site
929102006570	Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer,  utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cl00514
929102006571	dimer interface [polypeptide binding]; other site
929102006572	Predicted Fe-S oxidoreductases [General function prediction only]; Region: COG0535
929102006573	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
929102006574	FeS/SAM binding site; other site
929102006575	Predicted Fe-S oxidoreductases [General function prediction only]; Region: COG0535
929102006576	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
929102006577	FeS/SAM binding site; other site
929102006578	Major Facilitator Superfamily; Region: MFS_1; pfam07690
929102006579	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929102006580	non-specific DNA binding site [nucleotide binding]; other site
929102006581	salt bridge; other site
929102006582	sequence-specific DNA binding site [nucleotide binding]; other site
929102006583	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
929102006584	Predicted secreted protein containing a PDZ domain [Signal transduction mechanisms]; Region: SdrC; COG3480
929102006585	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
929102006586	protein binding site [polypeptide binding]; other site
929102006587	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
929102006588	Phosphopantetheine adenylyltransferase [Coenzyme metabolism]; Region: CoaD; COG0669
929102006589	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
929102006590	active site
929102006591	(T/H)XGH motif; other site
929102006592	Conserved hypothetical protein 95; Region: Cons_hypoth95; pfam03602
929102006593	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929102006594	S-adenosylmethionine binding site [chemical binding]; other site
929102006595	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929102006596	Major Facilitator Superfamily; Region: MFS_1; pfam07690
929102006597	putative substrate translocation pore; other site
929102006598	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
929102006599	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929102006600	DNA binding residues [nucleotide binding]
929102006601	Sigma factor regulator N-terminal; Region: Sigma_reg_N; pfam13800
929102006602	Sigma factor regulator C-terminal; Region: Sigma_reg_C; pfam13791
929102006603	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14097
929102006604	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
929102006605	active site
929102006606	dimer interface [polypeptide binding]; other site
929102006607	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
929102006608	dimer interface [polypeptide binding]; other site
929102006609	active site
929102006610	Flagellin N-methylase; Region: FliB; pfam03692
929102006611	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
929102006612	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
929102006613	NAD(P) binding site [chemical binding]; other site
929102006614	active site
929102006615	Predicted transcriptional regulators [Transcription]; Region: COG1733
929102006616	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
929102006617	putative DNA binding site [nucleotide binding]; other site
929102006618	dimerization interface [polypeptide binding]; other site
929102006619	putative Zn2+ binding site [ion binding]; other site
929102006620	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
929102006621	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
929102006622	active site
929102006623	HIGH motif; other site
929102006624	nucleotide binding site [chemical binding]; other site
929102006625	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
929102006626	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
929102006627	active site
929102006628	KMSKS motif; other site
929102006629	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
929102006630	tRNA binding surface [nucleotide binding]; other site
929102006631	anticodon binding site; other site
929102006632	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
929102006633	Fibronectin-binding protein (FBP); Region: FBP; pfam07299
929102006634	Domain of unknown function (DUF1912); Region: DUF1912; pfam08930
929102006635	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
929102006636	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929102006637	Coenzyme A binding pocket [chemical binding]; other site
929102006638	Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only]; Region: COG3382
929102006639	B3/4 domain; Region: B3_4; pfam03483
929102006640	TRAM domain; Region: TRAM; pfam01938
929102006641	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
929102006642	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929102006643	S-adenosylmethionine binding site [chemical binding]; other site
929102006644	recombination regulator RecX; Provisional; Region: recX; PRK14135
929102006645	fructuronate transporter; Provisional; Region: PRK10034; cl15264
929102006646	GntP family permease; Region: GntP_permease; pfam02447
929102006647	gluconate kinase, FGGY type; Region: gntK_FGGY; TIGR01314
929102006648	Gluconate kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_GntK; cd07770
929102006649	N- and C-terminal domain interface [polypeptide binding]; other site
929102006650	active site
929102006651	catalytic site [active]
929102006652	metal binding site [ion binding]; metal-binding site
929102006653	carbohydrate binding site [chemical binding]; other site
929102006654	ATP binding site [chemical binding]; other site
929102006655	Predicted 6-phosphogluconate dehydrogenase [Carbohydrate transport and metabolism]; Region: Gnd; COG1023
929102006656	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
929102006657	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
929102006658	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
929102006659	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
929102006660	putative active site [active]
929102006661	Staphylococcal protein of unknown function (DUF960); Region: DUF960; pfam06124
929102006662	phosphodiesterase YaeI; Provisional; Region: PRK11340
929102006663	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
929102006664	putative active site [active]
929102006665	putative metal binding site [ion binding]; other site
929102006666	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
929102006667	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
929102006668	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
929102006669	dimer interface [polypeptide binding]; other site
929102006670	ssDNA binding site [nucleotide binding]; other site
929102006671	tetramer (dimer of dimers) interface [polypeptide binding]; other site
929102006672	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
929102006673	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
929102006674	lysine transporter; Provisional; Region: PRK10836
929102006675	DNA polymerase III subunits gamma and tau; Validated; Region: PRK05563
929102006676	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929102006677	Walker A motif; other site
929102006678	ATP binding site [chemical binding]; other site
929102006679	Walker B motif; other site
929102006680	arginine finger; other site
929102006681	Predicted aminoglycoside phosphotransferase [General function prediction only]; Region: COG3173
929102006682	Phosphotransferase enzyme family; Region: APH; pfam01636
929102006683	substrate binding site [chemical binding]; other site
929102006684	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
929102006685	GAF domain; Region: GAF_2; pfam13185
929102006686	hypothetical protein; Provisional; Region: PRK07248
929102006687	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
929102006688	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
929102006689	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
929102006690	Int/Topo IB signature motif; other site
929102006691	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
929102006692	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929102006693	non-specific DNA binding site [nucleotide binding]; other site
929102006694	salt bridge; other site
929102006695	sequence-specific DNA binding site [nucleotide binding]; other site
929102006696	Protein of unknown function (Hypoth_ymh); Region: Hypoth_Ymh; pfam09509
929102006697	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929102006698	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
929102006699	non-specific DNA binding site [nucleotide binding]; other site
929102006700	salt bridge; other site
929102006701	sequence-specific DNA binding site [nucleotide binding]; other site
929102006702	Protein of unknown function (DUF1655); Region: DUF1655; pfam07868
929102006703	Prim_Pol: Primase-polymerase (primpol) domain of the type found in bifunctional replicases from archaeal plasmids, including ORF904 protein of the crenarchaeal plasmid pRN1 from Sulfolobus islandicus (pRN1 primpol). These primpol domains belong to the...; Region: Prim_Pol; cd04859
929102006704	polymerase nucleotide-binding site; other site
929102006705	DNA-binding residues [nucleotide binding]; DNA binding site
929102006706	nucleotide binding site [chemical binding]; other site
929102006707	primase nucleotide-binding site [nucleotide binding]; other site
929102006708	Primase C terminal 1 (PriCT-1); Region: PriCT_1; smart00942
929102006709	Phage associated DNA primase [General function prediction only]; Region: COG3378
929102006710	D5 N terminal like; Region: D5_N; smart00885
929102006711	Poxvirus D5 protein-like; Region: Pox_D5; pfam03288
929102006712	V-type ATP synthase subunit I; Validated; Region: PRK05771
929102006713	Phage head maturation protease [General function prediction only]; Region: COG3740
929102006714	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
929102006715	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
929102006716	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
929102006717	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
929102006718	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
929102006719	DNA binding residues [nucleotide binding]
929102006720	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
929102006721	Low molecular weight phosphatase family; Region: LMWPc; cd00115
929102006722	active site
929102006723	ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: COG3638
929102006724	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929102006725	Walker A/P-loop; other site
929102006726	ATP binding site [chemical binding]; other site
929102006727	Q-loop/lid; other site
929102006728	ABC transporter signature motif; other site
929102006729	Walker B; other site
929102006730	D-loop; other site
929102006731	H-loop/switch region; other site
929102006732	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883
929102006733	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
929102006734	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
929102006735	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929102006736	Walker A motif; other site
929102006737	ATP binding site [chemical binding]; other site
929102006738	Walker B motif; other site
929102006739	arginine finger; other site
929102006740	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
929102006741	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
929102006742	RuvA N terminal domain; Region: RuvA_N; pfam01330
929102006743	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786
929102006744	helix-hairpin-helix signature motif; other site
929102006745	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
929102006746	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
929102006747	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929102006748	ATP binding site [chemical binding]; other site
929102006749	Mg2+ binding site [ion binding]; other site
929102006750	G-X-G motif; other site
929102006751	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
929102006752	ATP binding site [chemical binding]; other site
929102006753	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
929102006754	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
929102006755	MutS domain I; Region: MutS_I; pfam01624
929102006756	MutS domain II; Region: MutS_II; pfam05188
929102006757	MutS domain III; Region: MutS_III; pfam05192
929102006758	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
929102006759	Walker A/P-loop; other site
929102006760	ATP binding site [chemical binding]; other site
929102006761	Q-loop/lid; other site
929102006762	ABC transporter signature motif; other site
929102006763	Walker B; other site
929102006764	D-loop; other site
929102006765	H-loop/switch region; other site
929102006766	Predicted membrane protein [Function unknown]; Region: COG4550
929102006767	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
929102006768	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
929102006769	Predicted membrane protein [Function unknown]; Region: COG4272
929102006770	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
929102006771	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
929102006772	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
929102006773	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
929102006774	Predicted hydrolase of the HAD superfamily [General function prediction only]; Region: COG2179
929102006775	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
929102006776	active site
929102006777	motif I; other site
929102006778	motif II; other site
929102006779	chaperone protein DnaJ; Provisional; Region: PRK14276
929102006780	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
929102006781	HSP70 interaction site [polypeptide binding]; other site
929102006782	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
929102006783	substrate binding site [polypeptide binding]; other site
929102006784	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
929102006785	Zn binding sites [ion binding]; other site
929102006786	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
929102006787	substrate binding site [polypeptide binding]; other site
929102006788	dimer interface [polypeptide binding]; other site
929102006789	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4990
929102006790	putative active site [active]
929102006791	Aspartate racemase [Cell envelope biogenesis, outer membrane]; Region: RacX; COG1794
929102006792	aspartate racemase; Region: asp_race; TIGR00035
929102006793	Predicted ATP-grasp enzyme [General function prediction only]; Region: COG3919
929102006794	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
929102006795	Asparagine synthase (glutamine-hydrolyzing) [Amino acid transport and metabolism]; Region: AsnB; COG0367
929102006796	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
929102006797	active site
929102006798	dimer interface [polypeptide binding]; other site
929102006799	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
929102006800	Ligand Binding Site [chemical binding]; other site
929102006801	Molecular Tunnel; other site
929102006802	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883
929102006803	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
929102006804	Surface antigen [General function prediction only]; Region: COG3942
929102006805	CHAP domain; Region: CHAP; pfam05257
929102006806	rod shape-determining protein MreD; Region: MreD; pfam04093
929102006807	Cell shape-determining protein [Cell envelope biogenesis, outer membrane]; Region: MreC; COG1792
929102006808	rod shape-determining protein MreC; Region: MreC; pfam04085
929102006809	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
929102006810	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
929102006811	active site
929102006812	DNA binding site [nucleotide binding]
929102006813	Int/Topo IB signature motif; other site
929102006814	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
929102006815	Peptidase S8 family domain in Subtilisin-like proteins; Region: Peptidases_S8_Subtilisin_like_2; cd04847
929102006816	active site
929102006817	catalytic triad [active]
929102006818	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
929102006819	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929102006820	Walker A motif; other site
929102006821	ATP binding site [chemical binding]; other site
929102006822	Walker B motif; other site
929102006823	arginine finger; other site
929102006824	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cl17393
929102006825	CHAP domain; Region: CHAP; pfam05257
929102006826	Uncharacterized protein conserved in bacteria (DUF2058); Region: DUF2058; cl01201
929102006827	AAA-like domain; Region: AAA_10; pfam12846
929102006828	Domain of unknown function DUF87; Region: DUF87; pfam01935
929102006829	TcpE family; Region: TcpE; pfam12648
929102006830	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
929102006831	Conjugative transposon protein TcpC; Region: TpcC; pfam12642
929102006832	Putative phage replication protein RstA [DNA replication, recombination, and repair]; Region: COG2946
929102006833	Replication initiation factor; Region: Rep_trans; pfam02486
929102006834	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929102006835	non-specific DNA binding site [nucleotide binding]; other site
929102006836	salt bridge; other site
929102006837	sequence-specific DNA binding site [nucleotide binding]; other site
929102006838	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
929102006839	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
929102006840	Bacterial protein of unknown function (DUF961); Region: DUF961; pfam06125
929102006841	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
929102006842	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929102006843	non-specific DNA binding site [nucleotide binding]; other site
929102006844	salt bridge; other site
929102006845	sequence-specific DNA binding site [nucleotide binding]; other site
929102006846	Domain of unknown function (DUF955); Region: DUF955; pfam06114
929102006847	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
929102006848	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
929102006849	Walker A/P-loop; other site
929102006850	ATP binding site [chemical binding]; other site
929102006851	Q-loop/lid; other site
929102006852	ABC transporter signature motif; other site
929102006853	Walker B; other site
929102006854	D-loop; other site
929102006855	H-loop/switch region; other site
929102006856	bacteriocin-associated integral membrane (putative immunity) protein; Region: bact_immun_7tm; TIGR01654
929102006857	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
929102006858	DNA-binding site [nucleotide binding]; DNA binding site
929102006859	RNA-binding motif; other site
929102006860	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
929102006861	DNA-binding site [nucleotide binding]; DNA binding site
929102006862	RNA-binding motif; other site
929102006863	Predicted transcriptional regulators [Transcription]; Region: COG1725
929102006864	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
929102006865	DNA-binding site [nucleotide binding]; DNA binding site
929102006866	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
929102006867	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929102006868	Walker A/P-loop; other site
929102006869	ATP binding site [chemical binding]; other site
929102006870	Q-loop/lid; other site
929102006871	ABC transporter signature motif; other site
929102006872	Walker B; other site
929102006873	D-loop; other site
929102006874	H-loop/switch region; other site
929102006875	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
929102006876	HSP70 interaction site [polypeptide binding]; other site
929102006877	Contains a crystal structure of the Nudix hydrolase from Enterococcus faecalis, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_25; cd04684
929102006878	nudix motif; other site
929102006879	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
929102006880	tetramer (dimer of dimers) interface [polypeptide binding]; other site
929102006881	active site
929102006882	dimer interface [polypeptide binding]; other site
929102006883	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
929102006884	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
929102006885	ligand binding site [chemical binding]; other site
929102006886	flexible hinge region; other site
929102006887	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
929102006888	putative switch regulator; other site
929102006889	non-specific DNA interactions [nucleotide binding]; other site
929102006890	DNA binding site [nucleotide binding]
929102006891	sequence specific DNA binding site [nucleotide binding]; other site
929102006892	putative cAMP binding site [chemical binding]; other site
929102006893	Major Facilitator Superfamily; Region: MFS_1; pfam07690
929102006894	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929102006895	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
929102006896	Ligand Binding Site [chemical binding]; other site
929102006897	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
929102006898	nucleotide binding site [chemical binding]; other site
929102006899	Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism]; Region: COG1924
929102006900	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
929102006901	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3580
929102006902	2-hydroxyglutaryl-CoA dehydratase, D-component; Region: HGD-D; pfam06050
929102006903	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3581
929102006904	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
929102006905	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
929102006906	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
929102006907	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
929102006908	RNA binding surface [nucleotide binding]; other site
929102006909	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
929102006910	active site
929102006911	uracil binding [chemical binding]; other site
929102006912	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
929102006913	Helix-turn-helix domain; Region: HTH_38; pfam13936
929102006914	Integrase core domain; Region: rve; pfam00665
929102006915	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
929102006916	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
929102006917	trmE is a tRNA modification GTPase; Region: trmE; cd04164
929102006918	G1 box; other site
929102006919	GTP/Mg2+ binding site [chemical binding]; other site
929102006920	Switch I region; other site
929102006921	G2 box; other site
929102006922	Switch II region; other site
929102006923	G3 box; other site
929102006924	G4 box; other site
929102006925	G5 box; other site
929102006926	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
929102006927	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
929102006928	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
929102006929	generic binding surface II; other site
929102006930	ssDNA binding site; other site
929102006931	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
929102006932	ATP binding site [chemical binding]; other site
929102006933	putative Mg++ binding site [ion binding]; other site
929102006934	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
929102006935	nucleotide binding region [chemical binding]; other site
929102006936	ATP-binding site [chemical binding]; other site
929102006937	Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824
929102006938	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
929102006939	PhnA protein; Region: PhnA; pfam03831
929102006940	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
929102006941	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
929102006942	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
929102006943	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
929102006944	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
929102006945	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
929102006946	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
929102006947	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
929102006948	motif II; other site
929102006949	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
929102006950	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
929102006951	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
929102006952	oxidoreductase; Provisional; Region: PRK06196
929102006953	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
929102006954	NAD(P) binding site [chemical binding]; other site
929102006955	active site
929102006956	CAAX protease self-immunity; Region: Abi; pfam02517
929102006957	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
929102006958	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
929102006959	23S rRNA interface [nucleotide binding]; other site
929102006960	L3 interface [polypeptide binding]; other site
929102006961	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
929102006962	FtsX-like permease family; Region: FtsX; pfam02687
929102006963	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
929102006964	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
929102006965	Walker A/P-loop; other site
929102006966	ATP binding site [chemical binding]; other site
929102006967	Q-loop/lid; other site
929102006968	ABC transporter signature motif; other site
929102006969	Walker B; other site
929102006970	D-loop; other site
929102006971	H-loop/switch region; other site
929102006972	ribonuclease HIII; Provisional; Region: PRK00996
929102006973	Domain of unknown function (DUF3378); Region: DUF3378; pfam11858
929102006974	bacterial Ribonuclease HIII-like; Region: RNase_HII_bacteria_HIII_like; cd06590
929102006975	RNA/DNA hybrid binding site [nucleotide binding]; other site
929102006976	active site
929102006977	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
929102006978	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
929102006979	Catalytic site [active]
929102006980	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
929102006981	pur operon repressor; Provisional; Region: PRK09213
929102006982	Bacterial purine repressor, N-terminal; Region: PuR_N; pfam09182
929102006983	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
929102006984	active site
929102006985	elongation factor G; Reviewed; Region: PRK00007
929102006986	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
929102006987	G1 box; other site
929102006988	putative GEF interaction site [polypeptide binding]; other site
929102006989	GTP/Mg2+ binding site [chemical binding]; other site
929102006990	Switch I region; other site
929102006991	G2 box; other site
929102006992	G3 box; other site
929102006993	Switch II region; other site
929102006994	G4 box; other site
929102006995	G5 box; other site
929102006996	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
929102006997	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
929102006998	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
929102006999	30S ribosomal protein S7; Validated; Region: PRK05302
929102007000	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
929102007001	S17 interaction site [polypeptide binding]; other site
929102007002	S8 interaction site; other site
929102007003	16S rRNA interaction site [nucleotide binding]; other site
929102007004	streptomycin interaction site [chemical binding]; other site
929102007005	23S rRNA interaction site [nucleotide binding]; other site
929102007006	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
929102007007	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
929102007008	Beta-lactamase; Region: Beta-lactamase; cl17358
929102007009	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
929102007010	Putative glucose uptake permease [Carbohydrate transport and metabolism]; Region: GlcU; COG4975
929102007011	Putative rRNA methylase; Region: rRNA_methylase; pfam06962
929102007012	Predicted Fe-S oxidoreductase [General function prediction only]; Region: COG1242
929102007013	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
929102007014	FeS/SAM binding site; other site
929102007015	Protein involved in initiation of plasmid replication [DNA replication, recombination, and repair]; Region: COG5527
929102007016	Initiator Replication protein; Region: Rep_3; pfam01051
929102007017	Lactococcus lactis RepB C-terminus; Region: L_lactis_RepB_C; pfam06430
929102007018	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
929102007019	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
929102007020	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
929102007021	ATP binding site [chemical binding]; other site
929102007022	putative Mg++ binding site [ion binding]; other site
929102007023	HsdM N-terminal domain; Region: HsdM_N; pfam12161
929102007024	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
929102007025	Methyltransferase domain; Region: Methyltransf_26; pfam13659
929102007026	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
929102007027	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
929102007028	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
929102007029	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
929102007030	uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u2; cd12827
929102007031	Cl binding site [ion binding]; other site
929102007032	oligomer interface [polypeptide binding]; other site
929102007033	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
929102007034	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
929102007035	metal binding site [ion binding]; metal-binding site
929102007036	dimer interface [polypeptide binding]; other site
929102007037	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
929102007038	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929102007039	putative substrate translocation pore; other site
929102007040	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
929102007041	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929102007042	Coenzyme A binding pocket [chemical binding]; other site
929102007043	VanZ like family; Region: VanZ; cl01971
929102007044	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3316
929102007045	Integrase core domain; Region: rve; pfam00665
929102007046	D-lactate dehydrogenase; Provisional; Region: PRK11183
929102007047	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
929102007048	conserved hypothetical integral membrane protein; Region: TIGR03766
929102007049	Domain of unknown function (DUF4158); Region: DUF4158; pfam13700
929102007050	Tn3 transposase DDE domain; Region: DDE_Tnp_Tn3; pfam01526
929102007051	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
929102007052	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
929102007053	catalytic residues [active]
929102007054	catalytic nucleophile [active]
929102007055	Presynaptic Site I dimer interface [polypeptide binding]; other site
929102007056	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
929102007057	Synaptic Flat tetramer interface [polypeptide binding]; other site
929102007058	Synaptic Site I dimer interface [polypeptide binding]; other site
929102007059	DNA binding site [nucleotide binding]
929102007060	MepB protein; Region: MepB; pfam08877
929102007061	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
929102007062	Ligand Binding Site [chemical binding]; other site
929102007063	manganese transport protein MntH; Reviewed; Region: PRK00701
929102007064	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
929102007065	HTH-like domain; Region: HTH_21; pfam13276
929102007066	Integrase core domain; Region: rve; pfam00665
929102007067	Bacterial mobilisation protein (MobC); Region: MobC; pfam05713
929102007068	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
929102007069	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
929102007070	Fic/DOC family; Region: Fic; cl00960
929102007071	Plasmid replication protein; Region: Rep_2; pfam01719
929102007072	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402