-- dump date 20140619_125611 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 272623000001 SEQ_END SEQ_END NC_002662.1 2365589 2365589 DR NC_002662.1; contig end 2365589..2365589 Lactococcus lactis subsp. lactis Il1403 NP_266157.1 CDS dnaA NC_002662.1 358 1725 D binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 358..1725 Lactococcus lactis subsp. lactis Il1403 1113599 NP_266158.1 CDS dnaN NC_002662.1 1882 3024 D binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 1882..3024 Lactococcus lactis subsp. lactis Il1403 1113600 NP_266159.1 CDS rexB NC_002662.1 3130 6429 D evidence experimental PMID:9435243; exonuclease is specifically blocked by the lactococcal Chi site (5'-GCGCGTG-3'); RexAB-mediated recombination stimulated approximately 27-fold by lactococcal Chi; subunit B of ATP-dependent exonuclease 3130..6429 Lactococcus lactis subsp. lactis Il1403 1113601 NP_266160.1 CDS rexA NC_002662.1 6422 10033 D ATP-dependent exonuclease subunit a 6422..10033 Lactococcus lactis subsp. lactis Il1403 1113602 NP_835283.1 CDS L200000 NC_002662.1 10070 10270 D hypothetical protein 10070..10270 Lactococcus lactis subsp. lactis Il1403 1113603 NP_266161.1 CDS yabA NC_002662.1 10280 10837 R belongs to the PBSX(XRE) family of transcription regulators; transcriptional regulator complement(10280..10837) Lactococcus lactis subsp. lactis Il1403 1113604 NP_266162.1 CDS yyaL NC_002662.1 11119 12234 D translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 11119..12234 Lactococcus lactis subsp. lactis Il1403 1113605 NP_266163.1 CDS yabB NC_002662.1 12346 12669 D belongs to the PBSX(XRE) family of transcription regulators; transcriptional regulator 12346..12669 Lactococcus lactis subsp. lactis Il1403 1113606 NP_266164.1 CDS yabC NC_002662.1 12924 13268 D hypothetical protein 12924..13268 Lactococcus lactis subsp. lactis Il1403 1113607 NP_266165.1 CDS yabD NC_002662.1 13281 15272 D hypothetical protein 13281..15272 Lactococcus lactis subsp. lactis Il1403 1113608 NP_266166.1 CDS yabE NC_002662.1 15274 15909 D transport and binding protein; ABC transporter ATP-binding protein 15274..15909 Lactococcus lactis subsp. lactis Il1403 1113609 NP_266167.1 CDS yabF NC_002662.1 16110 16580 D hypothetical protein 16110..16580 Lactococcus lactis subsp. lactis Il1403 1113610 NP_266168.1 CDS pth NC_002662.1 16598 17164 D Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 16598..17164 Lactococcus lactis subsp. lactis Il1403 1113611 NP_266169.1 CDS mfd NC_002662.1 17165 20650 D transcription-repair coupling factor 17165..20650 Lactococcus lactis subsp. lactis Il1403 1113612 NP_266170.1 CDS yacI NC_002662.1 20810 21280 D hypothetical protein 20810..21280 Lactococcus lactis subsp. lactis Il1403 1113613 NP_266171.1 CDS yacB NC_002662.1 21351 21668 D hypothetical protein 21351..21668 Lactococcus lactis subsp. lactis Il1403 1113614 NP_266172.1 CDS yacC NC_002662.1 21697 22071 D similar to cell division protein DivIC of Bacillus subtilis; in Bacillus subtilis required for activation of genes expressed under the control of the sigma E and sigma F; hypothetical protein 21697..22071 Lactococcus lactis subsp. lactis Il1403 1113615 NP_266173.1 CDS yacD NC_002662.1 22071 22394 D similar to Bacillus subtilis hypothetical 14.2 kDa protein; hypothetical protein 22071..22394 Lactococcus lactis subsp. lactis Il1403 1113616 NP_266174.1 CDS yacG NC_002662.1 22532 23881 D hypothetical protein 22532..23881 Lactococcus lactis subsp. lactis Il1403 1113617 NP_266175.1 CDS mesJ NC_002662.1 23878 25149 D cell cycle protein; hypothetical protein 23878..25149 Lactococcus lactis subsp. lactis Il1403 1113618 NP_266176.1 CDS hpt NC_002662.1 25130 25681 D evidence experimental PMID:1465108; hypoxanthine phosphoribosyltransferase 25130..25681 Lactococcus lactis subsp. lactis Il1403 1113619 NP_266177.1 CDS ftsH NC_002662.1 25887 27974 D cell division protein; evidence experimental PMID:8000529; hypothetical protein 25887..27974 Lactococcus lactis subsp. lactis Il1403 1113620 NP_266178.1 CDS mtlR NC_002662.1 30922 32859 D LysR-family regulator; probable regulator of mtl operon; LysR family transcriptional regulator 30922..32859 Lactococcus lactis subsp. lactis Il1403 1113621 NP_266179.1 CDS mtlF NC_002662.1 32907 33338 D transport and binding protein; PTS system; PTS system mannitol-specific transporter subunit IIA 32907..33338 Lactococcus lactis subsp. lactis Il1403 1113622 NP_266180.1 CDS mtlD NC_002662.1 33476 34633 D energy metabolism; mannitol-1-phosphate 5-dehydrogenase 33476..34633 Lactococcus lactis subsp. lactis Il1403 1113623 NP_266181.1 CDS ps101 NC_002662.1 35516 35839 R similar to bacterial sigma factors; prophage ps1 protein 01 complement(35516..35839) Lactococcus lactis subsp. lactis Il1403 1113624 NP_266182.1 CDS ps102 NC_002662.1 35864 36274 R similar to a hypothetical protein of Lactococcus lactis subsp. cremoris S114 Y11901; prophage ps1 protein 02 complement(35864..36274) Lactococcus lactis subsp. lactis Il1403 1113625 NP_266183.1 CDS ps103 NC_002662.1 36271 36714 R prophage ps1 protein 03; essential for phage DNA maturation and packaging; terminase subunit complement(36271..36714) Lactococcus lactis subsp. lactis Il1403 1113626 NP_266184.1 CDS ps104 NC_002662.1 36847 37428 R prophage ps1 protein 04 complement(36847..37428) Lactococcus lactis subsp. lactis Il1403 1113627 NP_266185.1 CDS ps105 NC_002662.1 37664 39292 R prophage ps1 protein 05; similar to primase of Streptococcus thermophilus bacteriophage DT1; DNA primase complement(37664..39292) Lactococcus lactis subsp. lactis Il1403 1113628 NP_266186.1 CDS ps106 NC_002662.1 39303 40097 R similar to Orf1 of Streptococcus thermophilus bacteriophage SFi18; prophage ps1 protein 06 complement(39303..40097) Lactococcus lactis subsp. lactis Il1403 1113629 NP_266187.1 CDS ps107 NC_002662.1 40101 40430 R prophage ps1 protein 07 complement(40101..40430) Lactococcus lactis subsp. lactis Il1403 1113630 NP_835284.1 CDS L200001 NC_002662.1 40417 40611 R prophage ps2 protein 12 complement(40417..40611) Lactococcus lactis subsp. lactis Il1403 1113631 NP_266188.1 CDS ps108 NC_002662.1 40608 40862 R prophage ps1 protein 08 complement(40608..40862) Lactococcus lactis subsp. lactis Il1403 1113632 NP_266189.1 CDS ps109 NC_002662.1 40859 41098 R prophage ps1 protein 09 complement(40859..41098) Lactococcus lactis subsp. lactis Il1403 1113633 NP_266190.1 CDS ps110 NC_002662.1 41141 41422 R prophage ps1 protein 10 complement(41141..41422) Lactococcus lactis subsp. lactis Il1403 1113634 NP_266191.1 CDS ps111 NC_002662.1 41419 41670 R PBSX(XRE) family of transcription regulators; prophage ps1 protein 11 complement(41419..41670) Lactococcus lactis subsp. lactis Il1403 1113635 NP_266192.1 CDS ps112 NC_002662.1 41667 42188 R similar to a DNA polymerase of Neurospora crassa mitochondrion plasmid maranhar; prophage ps1 protein 12 complement(41667..42188) Lactococcus lactis subsp. lactis Il1403 1113636 NP_266193.1 CDS ps113 NC_002662.1 42192 42386 R prophage ps1 protein 13 complement(42192..42386) Lactococcus lactis subsp. lactis Il1403 1113637 NP_266194.1 CDS ps114 NC_002662.1 42462 43202 R similar to Rha protein of Escherichia coli phage phi-80; prophage ps1 protein 14 complement(42462..43202) Lactococcus lactis subsp. lactis Il1403 1113638 NP_835285.1 CDS L200002 NC_002662.1 43231 43407 R bacteriophage bIL310 repressor complement(43231..43407) Lactococcus lactis subsp. lactis Il1403 1113639 NP_266195.1 CDS ps115 NC_002662.1 43689 44075 D transcription regulator; similar to Rad protein of Lactobacillus bacteriophage phi adh; prophage ps1 protein 15 43689..44075 Lactococcus lactis subsp. lactis Il1403 1113640 NP_266196.1 CDS ps116 NC_002662.1 44085 44639 D prophage ps1 protein 16 44085..44639 Lactococcus lactis subsp. lactis Il1403 1113641 NP_266197.1 CDS ps117 NC_002662.1 44750 44980 D prophage ps1 protein 17 44750..44980 Lactococcus lactis subsp. lactis Il1403 1113642 NP_266198.1 CDS ps118 NC_002662.1 45053 45247 D hypothetical protein 45053..45247 Lactococcus lactis subsp. lactis Il1403 1113643 NP_266199.1 CDS ps119 NC_002662.1 45399 45641 D prophage ps1 protein 19 45399..45641 Lactococcus lactis subsp. lactis Il1403 1113644 NP_266200.1 CDS ps120 NC_002662.1 45777 46001 D prophage ps1 protein 20 45777..46001 Lactococcus lactis subsp. lactis Il1403 1113645 NP_835286.1 CDS L200003 NC_002662.1 46648 46794 D hypothetical protein 46648..46794 Lactococcus lactis subsp. lactis Il1403 1113646 NP_266201.1 CDS ps121 NC_002662.1 47370 47585 D prophage ps1 protein 21 47370..47585 Lactococcus lactis subsp. lactis Il1403 1113647 NP_835287.1 CDS L200004 NC_002662.1 47702 47866 D bacteriophage bIL310 Orf3 47702..47866 Lactococcus lactis subsp. lactis Il1403 1113648 NP_266202.1 CDS ps122 NC_002662.1 47988 48293 D similar to lactococcin A immunity protein; prophage ps1 protein 22 47988..48293 Lactococcus lactis subsp. lactis Il1403 1113649 NP_266203.1 CDS ps123 NC_002662.1 48543 49727 D prophage ps1 protein 23; integrase 48543..49727 Lactococcus lactis subsp. lactis Il1403 1113650 NP_266204.1 CDS yafE NC_002662.1 50180 50629 D paralogous to yfhA; hypothetical protein 50180..50629 Lactococcus lactis subsp. lactis Il1403 1113651 NP_266205.1 CDS yafF NC_002662.1 50706 50948 D hypothetical protein 50706..50948 Lactococcus lactis subsp. lactis Il1403 1113652 NP_266206.1 CDS yafB NC_002662.1 51029 52411 R transport and binding protein, anions; similar to several sulfate transporters; sulfate transporter complement(51029..52411) Lactococcus lactis subsp. lactis Il1403 1113653 NP_266208.1 CDS L0466 NC_002662.1 53161 53844 D evidence experimental PMID:1328163; transposon related function; IS3/IS150/IS904 family transposase; IS1077A transposase 53161..53844 Lactococcus lactis subsp. lactis Il1403 1113655 NP_266209.1 CDS tra904A NC_002662.1 53900 54661 R evidence experimental PMID:1328163; transposon related function; IS3/IS150/IS904 family transposase; transposase of IS904A complement(53900..54661) Lactococcus lactis subsp. lactis Il1403 1113656 NP_266210.1 CDS yafI NC_002662.1 54757 55047 R transposon related function; hypothetical protein complement(54757..55047) Lactococcus lactis subsp. lactis Il1403 1113657 NP_266211.1 CDS yafJ NC_002662.1 55126 55389 R similar to hypothetical protein YvdB from Bacillus subtilis; hypothetical protein complement(55126..55389) Lactococcus lactis subsp. lactis Il1403 1113658 NP_266212.1 CDS yafC NC_002662.1 55599 56120 D hypothetical protein 55599..56120 Lactococcus lactis subsp. lactis Il1403 1113659 NP_266213.1 CDS araT NC_002662.1 56584 57759 D catalyzes the transamination of the aromatic amino acid forming a ketoacid; first step in aromatic amino acid degradation in lactococci; aromatic amino acid aminotransferase 56584..57759 Lactococcus lactis subsp. lactis Il1403 1113660 NP_266214.1 CDS recO NC_002662.1 57858 58613 D involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 57858..58613 Lactococcus lactis subsp. lactis Il1403 1113661 NP_266215.1 CDS pdhD NC_002662.1 58971 60389 R E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase complement(58971..60389) Lactococcus lactis subsp. lactis Il1403 1113662 NP_266216.1 CDS pdhC NC_002662.1 60583 62181 R pyruvate dehydrogenase; dihydrolipoamide acetyltransferase component of PDH complex complement(60583..62181) Lactococcus lactis subsp. lactis Il1403 1113663 NP_266217.1 CDS pdhB NC_002662.1 62174 63154 R pyruvate dehydrogenase; PDH E1 component subunit beta complement(62174..63154) Lactococcus lactis subsp. lactis Il1403 1113664 NP_266218.1 CDS pdhA NC_002662.1 63157 64281 R pyruvate dehydrogenase; PDH E1 component subunit alpha complement(63157..64281) Lactococcus lactis subsp. lactis Il1403 1113665 NP_266219.1 CDS lplL NC_002662.1 64370 65371 R lipoate-protein ligase complement(64370..65371) Lactococcus lactis subsp. lactis Il1403 1113666 NP_266220.1 CDS yagA NC_002662.1 65571 66416 R similar to glycerophosphoryl diester phosphodiesterases; hypothetical protein complement(65571..66416) Lactococcus lactis subsp. lactis Il1403 1113667 NP_266221.1 CDS yagB NC_002662.1 66497 67147 R exists in AT rich gram positives and in archae; hypothetical protein complement(66497..67147) Lactococcus lactis subsp. lactis Il1403 1113668 NP_266222.1 CDS trpS NC_002662.1 67264 68289 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase II complement(67264..68289) Lactococcus lactis subsp. lactis Il1403 1113669 NP_266223.1 CDS osmC NC_002662.1 68791 69228 D adaptations and atypical conditions; similar to osmotically inducible protein OsmC of Escherichia coli; osmotically inducible protein 68791..69228 Lactococcus lactis subsp. lactis Il1403 1113670 NP_266224.1 CDS yagE NC_002662.1 69389 70702 D transport and binding protein; amino acids, peptides and amines; similar to many amino acid permeases; amino acid permease 69389..70702 Lactococcus lactis subsp. lactis Il1403 1113671 NP_266225.1 CDS yahC NC_002662.1 70762 71112 D hypothetical protein 70762..71112 Lactococcus lactis subsp. lactis Il1403 1113672 NP_266226.1 CDS plsX NC_002662.1 71171 72166 R involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX complement(71171..72166) Lactococcus lactis subsp. lactis Il1403 1113673 NP_266227.1 CDS yahA NC_002662.1 72269 73081 R hypothetical protein complement(72269..73081) Lactococcus lactis subsp. lactis Il1403 1113674 NP_266228.1 CDS yahG NC_002662.1 73207 74844 R transport and binding protein; contains two ATP binding domains; ABC transporter ATP-binding protein complement(73207..74844) Lactococcus lactis subsp. lactis Il1403 1113675 NP_266229.1 CDS cysD NC_002662.1 75972 77252 R O-acetylhomoserine sulfhydrylase complement(75972..77252) Lactococcus lactis subsp. lactis Il1403 1113676 NP_266230.1 CDS yahI NC_002662.1 77479 78312 R aerobic energy metabolism; short-chain type dehydrogenase complement(77479..78312) Lactococcus lactis subsp. lactis Il1403 1113677 NP_266231.1 CDS yahB NC_002662.1 78713 79180 D hypothetical protein 78713..79180 Lactococcus lactis subsp. lactis Il1403 1113678 NP_835288.1 CDS L200005 NC_002662.1 79309 79506 D hypothetical protein 79309..79506 Lactococcus lactis subsp. lactis Il1403 1113679 NP_266232.1 CDS yahD NC_002662.1 79537 80157 D hypothetical protein 79537..80157 Lactococcus lactis subsp. lactis Il1403 1113680 NP_266233.1 CDS yaiA NC_002662.1 80208 81377 D hypothetical protein 80208..81377 Lactococcus lactis subsp. lactis Il1403 1113681 NP_266234.1 CDS yaiB NC_002662.1 81388 81978 D hypothetical protein 81388..81978 Lactococcus lactis subsp. lactis Il1403 1113682 NP_266235.1 CDS lcnC NC_002662.1 82576 84723 D lactococcin A ABC transporter ATP-binding protein/permease 82576..84723 Lactococcus lactis subsp. lactis Il1403 1113683 NP_266236.1 CDS lcnD NC_002662.1 84738 86159 D evidence experimental PMID:8633867; transport and binding protein; multidrug resistance; in the strain diacetylactis WM4 involved in secretion of lactococcin A; HlyD family of secretion proteins; lactococcin A ABC transporter permease 84738..86159 Lactococcus lactis subsp. lactis Il1403 1113684 NP_266237.1 CDS yaiE NC_002662.1 86620 87072 D transport and binding protein; transporter 86620..87072 Lactococcus lactis subsp. lactis Il1403 1113685 NP_266238.1 CDS yaiF NC_002662.1 87111 87767 D hypothetical protein 87111..87767 Lactococcus lactis subsp. lactis Il1403 1113686 NP_266239.1 CDS yaiI NC_002662.1 87870 88151 R hypothetical protein complement(87870..88151) Lactococcus lactis subsp. lactis Il1403 1113687 NP_835289.1 CDS yaiJ NC_002662.1 88161 88313 R hypothetical protein complement(88161..88313) Lactococcus lactis subsp. lactis Il1403 1113688 NP_266240.1 CDS yaiG NC_002662.1 88652 88870 D similar to LcnD of Lactococcus lactis; hypothetical protein 88652..88870 Lactococcus lactis subsp. lactis Il1403 1113689 NP_266241.1 CDS yaiH NC_002662.1 89117 89827 D similar to OrfX from AbiG region of plasmid pCI750 from Lactococcus lactis subsp. cremoris UC653; hypothetical protein 89117..89827 Lactococcus lactis subsp. lactis Il1403 1113690 NP_266242.1 CDS yajA NC_002662.1 90253 90705 D transport and binding protein; similar to several membrane proteins; transporter 90253..90705 Lactococcus lactis subsp. lactis Il1403 1113691 NP_266243.1 CDS tra981A NC_002662.1 91052 91891 R evidence experimental PMID:8389385; transposon related function; related to a family of IS elements that includes IS2, IS3, IS150, IS600, IS629, IS861, IS904 and ISL1; transposase of IS981A complement(91052..91891) Lactococcus lactis subsp. lactis Il1403 1113692 NP_266244.1 CDS yajE NC_002662.1 91903 92163 R transposon related function; orf1 of IS981; transposase complement(91903..92163) Lactococcus lactis subsp. lactis Il1403 1113693 NP_266245.1 CDS yajF NC_002662.1 92200 92805 R similar to OrfX from AbiG region of plasmid pCI750 from Lactococcus lactis subsp. cremoris UC653; hypothetical protein complement(92200..92805) Lactococcus lactis subsp. lactis Il1403 1113694 YP_008998699.1 CDS L92205a NC_002662.1 93031 93621 R transposase complement(93031..93621) Lactococcus lactis subsp. lactis Il1403 18245207 NP_266246.1 CDS yajG NC_002662.1 93882 94142 R transposon related function; orf1 of IS981; transposase complement(93882..94142) Lactococcus lactis subsp. lactis Il1403 1113696 NP_266247.1 CDS yajB NC_002662.1 94253 94621 D hypothetical protein 94253..94621 Lactococcus lactis subsp. lactis Il1403 1113697 NP_266248.1 CDS yajH NC_002662.1 94841 95143 R hypothetical protein complement(94841..95143) Lactococcus lactis subsp. lactis Il1403 1113698 NP_266249.1 CDS rpmG NC_002662.1 95879 96028 R in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 complement(95879..96028) Lactococcus lactis subsp. lactis Il1403 1113699 NP_266250.1 CDS rpmF NC_002662.1 96058 96231 R some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 complement(96058..96231) Lactococcus lactis subsp. lactis Il1403 1113700 NP_266251.1 CDS cadA NC_002662.1 96595 98376 D transort and binding protein, cations; cation transport ATPase family (E1-E2 ATPase); cadmium efflux ATPase 96595..98376 Lactococcus lactis subsp. lactis Il1403 1113701 NP_266252.1 CDS parA NC_002662.1 98429 99214 R chromosome partitioning protein complement(98429..99214) Lactococcus lactis subsp. lactis Il1403 1113702 NP_266253.1 CDS cshA NC_002662.1 99269 100528 R recombination factor protein RarA complement(99269..100528) Lactococcus lactis subsp. lactis Il1403 1113703 NP_266254.1 CDS ybaH NC_002662.1 100572 101060 R DNA replication, restriction, modification, recombination, and repair; acetyl transferase complement(100572..101060) Lactococcus lactis subsp. lactis Il1403 1113704 NP_266255.1 CDS ybaA NC_002662.1 101212 101679 D hypothetical protein 101212..101679 Lactococcus lactis subsp. lactis Il1403 1113705 NP_266256.1 CDS ybaB NC_002662.1 101709 103262 D transport and binding protein; contains two ATP binding domains; ABC transporter ATP-binding protein 101709..103262 Lactococcus lactis subsp. lactis Il1403 1113706 NP_266257.1 CDS ybaC NC_002662.1 103393 103677 D hypothetical protein 103393..103677 Lactococcus lactis subsp. lactis Il1403 1113707 NP_266258.1 CDS ybaD NC_002662.1 103715 104203 D hypothetical protein 103715..104203 Lactococcus lactis subsp. lactis Il1403 1113708 NP_266259.1 CDS prmA NC_002662.1 104221 105174 D methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 104221..105174 Lactococcus lactis subsp. lactis Il1403 1113709 NP_266260.1 CDS ybaF NC_002662.1 105274 106026 D in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 105274..106026 Lactococcus lactis subsp. lactis Il1403 1113710 NP_266261.1 CDS ybaG NC_002662.1 106055 107011 D hypothetical protein 106055..107011 Lactococcus lactis subsp. lactis Il1403 1113711 NP_266262.1 CDS relA NC_002662.1 107212 109434 D general regulatory function; ppGpp synthetase I 107212..109434 Lactococcus lactis subsp. lactis Il1403 1113712 NP_266263.1 CDS ybaI NC_002662.1 109450 110385 R glycosyltransferase family 2; glycosyl transferase complement(109450..110385) Lactococcus lactis subsp. lactis Il1403 1113713 NP_266264.1 CDS ybbA NC_002662.1 110576 111031 D hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 110576..111031 Lactococcus lactis subsp. lactis Il1403 1113714 NP_266265.1 CDS ybbB NC_002662.1 111024 112019 D hypothetical protein 111024..112019 Lactococcus lactis subsp. lactis Il1403 1113715 NP_266266.1 CDS ybbC NC_002662.1 112022 112645 D hypothetical protein 112022..112645 Lactococcus lactis subsp. lactis Il1403 1113716 NP_266267.1 CDS ctrA NC_002662.1 112785 114194 D transport and binding protein; amino acids, peptides and amines; similar to many cationic amino acid transporters; cationic amino acid transporter 112785..114194 Lactococcus lactis subsp. lactis Il1403 1113717 NP_266268.1 CDS ybbE NC_002662.1 114343 114984 D hypothetical protein 114343..114984 Lactococcus lactis subsp. lactis Il1403 1113718 NP_266269.1 CDS rmaD NC_002662.1 115022 115513 R MarR-family regulator; transcriptional regulator complement(115022..115513) Lactococcus lactis subsp. lactis Il1403 1113719 NP_266270.1 CDS acpD NC_002662.1 115548 116192 R converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine residue from ACP; probable NAD(P)H dehydrogenase; ACP phosphodiesterase complement(115548..116192) Lactococcus lactis subsp. lactis Il1403 1113720 NP_266271.1 CDS secA NC_002662.1 116366 118963 D functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 116366..118963 Lactococcus lactis subsp. lactis Il1403 1113721 NP_266272.1 CDS aroF NC_002662.1 119092 120129 D catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 119092..120129 Lactococcus lactis subsp. lactis Il1403 1113722 NP_266273.1 CDS ptsH NC_002662.1 120380 120646 D transport and binding protein; PTS system; phosphocarrier protein HPr 120380..120646 Lactococcus lactis subsp. lactis Il1403 1113723 NP_266274.1 CDS ptsI NC_002662.1 120649 122376 D transport and binding protein; PTS system; PTS system enzyme I; phosphoenolpyruvate-protein phosphotransferase 120649..122376 Lactococcus lactis subsp. lactis Il1403 1113724 NP_266275.1 CDS ybcC NC_002662.1 122491 122805 D hypothetical protein 122491..122805 Lactococcus lactis subsp. lactis Il1403 1113725 NP_266276.1 CDS ybcG NC_002662.1 122846 123145 R hypothetical protein complement(122846..123145) Lactococcus lactis subsp. lactis Il1403 1113726 NP_266277.1 CDS ybcH NC_002662.1 123533 124468 R hypothetical protein complement(123533..124468) Lactococcus lactis subsp. lactis Il1403 1113727 NP_266278.1 CDS sugE NC_002662.1 124677 125030 D chaperones; SugE protein 124677..125030 Lactococcus lactis subsp. lactis Il1403 1113728 NP_266279.1 CDS blt NC_002662.1 125152 126315 D multidrug resistance; multidrug efflux transporter 125152..126315 Lactococcus lactis subsp. lactis Il1403 1113729 NP_266280.2 CDS argG NC_002662.1 126757 127950 D catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase 126757..127950 Lactococcus lactis subsp. lactis Il1403 1113730 NP_266281.1 CDS argH NC_002662.1 127981 129360 D catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 127981..129360 Lactococcus lactis subsp. lactis Il1403 1113731 NP_266282.1 CDS pmrB NC_002662.1 129376 130572 R transport and binding protein; multidrug resistance; similar to PmrA of Streptococcus pneumoniae; multidrug resistance efflux pump complement(129376..130572) Lactococcus lactis subsp. lactis Il1403 1113732 NP_266283.1 CDS ybdA NC_002662.1 130767 131342 D similar to Escherichia coli tetracycline repressor protein; transcriptional regulator 130767..131342 Lactococcus lactis subsp. lactis Il1403 1113733 NP_266284.1 CDS rnpA NC_002662.1 131494 131847 D protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 131494..131847 Lactococcus lactis subsp. lactis Il1403 1113734 NP_266285.1 CDS ybdC NC_002662.1 131844 132653 D similar to SpoIIIJ protein of Bacillus subtilis; attached to membrane by a lipid anchor; hypothetical protein 131844..132653 Lactococcus lactis subsp. lactis Il1403 1113735 NP_266286.1 CDS ybdD NC_002662.1 132742 133656 D similar to spoIIIJ-associated protein Jag protein from differenr species; hypothetical protein 132742..133656 Lactococcus lactis subsp. lactis Il1403 1113736 NP_266287.1 CDS rpmH NC_002662.1 133788 133922 D in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 133788..133922 Lactococcus lactis subsp. lactis Il1403 1113737 NP_266288.1 CDS ybdG NC_002662.1 135110 135430 D belongs to the PBSX(XRE) family of transcription regulators; transcriptional regulator 135110..135430 Lactococcus lactis subsp. lactis Il1403 1113739 NP_266289.1 CDS ybdH NC_002662.1 135561 135788 D hypothetical protein 135561..135788 Lactococcus lactis subsp. lactis Il1403 1113740 NP_266290.1 CDS ybdI NC_002662.1 135966 136511 D similar to OrfX from AbiG region of plasmid pCI750 from Lactococcus lactis subsp. cremoris UC653; hypothetical protein 135966..136511 Lactococcus lactis subsp. lactis Il1403 1113741 NP_266291.1 CDS ybdJ NC_002662.1 136564 137244 D similar to OrfX from AbiG region of plasmid pCI750 from Lactococcus lactis subsp. cremoris UC653; hypothetical protein 136564..137244 Lactococcus lactis subsp. lactis Il1403 1113742 NP_266292.1 CDS ybdK NC_002662.1 137413 137703 D transposon related function; hypothetical protein 137413..137703 Lactococcus lactis subsp. lactis Il1403 1113743 NP_266293.1 CDS tra904B NC_002662.1 137799 138560 D evidence experimental PMID:1328163; transposon related function; IS3/IS150/IS904 family transposase; transposase of IS904B 137799..138560 Lactococcus lactis subsp. lactis Il1403 1113744 NP_266294.1 CDS ybdL NC_002662.1 138617 139174 D transposon related function; hypothetical protein 138617..139174 Lactococcus lactis subsp. lactis Il1403 1113745 NP_266295.1 CDS tra1077B NC_002662.1 139171 139989 D evidence experimental PMID:1328163; transposon related function; IS3/IS150/IS904 family transposase; IS1077B transposase 139171..139989 Lactococcus lactis subsp. lactis Il1403 1113746 NP_266296.1 CDS tra904C NC_002662.1 140045 140806 R evidence experimental PMID:1328163; transposon related function; IS3/IS150/IS904 family transposase; transposase of IS904C complement(140045..140806) Lactococcus lactis subsp. lactis Il1403 1113747 NP_266297.1 CDS ybeG NC_002662.1 140902 141192 R transposon related function; hypothetical protein complement(140902..141192) Lactococcus lactis subsp. lactis Il1403 1113748 NP_266298.1 CDS ybeA NC_002662.1 141497 141763 D hypothetical protein 141497..141763 Lactococcus lactis subsp. lactis Il1403 1113749 NP_266299.1 CDS ybeB NC_002662.1 141835 142194 D similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 141835..142194 Lactococcus lactis subsp. lactis Il1403 1113750 NP_266300.1 CDS ybeC NC_002662.1 142347 142670 D similar to YrzB of Bacillus subtilis; hypothetical protein 142347..142670 Lactococcus lactis subsp. lactis Il1403 1113751 NP_266301.1 CDS ybeH NC_002662.1 142701 143252 R hypothetical protein complement(142701..143252) Lactococcus lactis subsp. lactis Il1403 1113752 NP_266302.1 CDS cbr NC_002662.1 143347 144132 R aerobic energy metabolism; short-chain dehydrogenases/reductases family; carbonyl reductase complement(143347..144132) Lactococcus lactis subsp. lactis Il1403 1113753 NP_266303.1 CDS ybeI NC_002662.1 144152 144397 R hypothetical protein complement(144152..144397) Lactococcus lactis subsp. lactis Il1403 1113754 NP_266304.1 CDS dltE NC_002662.1 144407 145192 R surface polysaccharides, lipopolysaccharides and antigens; short-chain dehydrogenase/reductase family; oxidoreductase complement(144407..145192) Lactococcus lactis subsp. lactis Il1403 1113755 NP_266305.1 CDS ybeD NC_002662.1 145304 145849 D TetR/AcrR family of transcription regulators; transcriptional regulator 145304..145849 Lactococcus lactis subsp. lactis Il1403 1113756 NP_266306.1 CDS ybeM NC_002662.1 148003 148323 R hypothetical protein complement(148003..148323) Lactococcus lactis subsp. lactis Il1403 1113758 NP_266307.1 CDS ybeF NC_002662.1 148795 154746 D hypothetical protein 148795..154746 Lactococcus lactis subsp. lactis Il1403 1113759 NP_266308.1 CDS tgt NC_002662.1 155375 156523 R Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase complement(155375..156523) Lactococcus lactis subsp. lactis Il1403 1113760 NP_266309.1 CDS ybfA NC_002662.1 156715 157407 D hypothetical protein 156715..157407 Lactococcus lactis subsp. lactis Il1403 1113761 NP_266310.1 CDS ybfD NC_002662.1 157468 158649 R transport and binding protein; multidrug resistance; similar to several quinolene resistance proteins NorA; transporter complement(157468..158649) Lactococcus lactis subsp. lactis Il1403 1113762 NP_266311.1 CDS ybfE NC_002662.1 158830 159267 R hypothetical protein complement(158830..159267) Lactococcus lactis subsp. lactis Il1403 1113763 NP_266312.1 CDS ybfB NC_002662.1 159402 160193 D similar to streptodornase (DNAse) from Streptococcus pyogenes; hypothetical protein 159402..160193 Lactococcus lactis subsp. lactis Il1403 1113764 NP_266313.1 CDS ybfC NC_002662.1 160358 160567 D hypothetical protein 160358..160567 Lactococcus lactis subsp. lactis Il1403 1113765 NP_266314.1 CDS ybgA NC_002662.1 160579 160818 D hypothetical protein 160579..160818 Lactococcus lactis subsp. lactis Il1403 1113766 NP_266315.1 CDS ybgB NC_002662.1 161014 162597 D hypothetical protein 161014..162597 Lactococcus lactis subsp. lactis Il1403 1113767 NP_266316.1 CDS aspC NC_002662.1 162666 163880 D broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT 162666..163880 Lactococcus lactis subsp. lactis Il1403 1113768 NP_266317.1 CDS codY NC_002662.1 164033 164821 D CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; transcriptional repressor CodY 164033..164821 Lactococcus lactis subsp. lactis Il1403 1113769 NP_266318.1 CDS gatC NC_002662.1 165330 165635 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 165330..165635 Lactococcus lactis subsp. lactis Il1403 1113770 NP_266319.1 CDS gatA NC_002662.1 165635 167095 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 165635..167095 Lactococcus lactis subsp. lactis Il1403 1113771 NP_266320.1 CDS ybgD NC_002662.1 167099 167701 D similar to several MutT-like proteins; hypothetical protein 167099..167701 Lactococcus lactis subsp. lactis Il1403 1113772 NP_266321.2 CDS gatB NC_002662.1 167741 169174 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 167741..169174 Lactococcus lactis subsp. lactis Il1403 1113773 NP_266322.1 CDS ybgE NC_002662.1 169398 170897 D similar to 6-aminohexanoate-cyclic-dimer hydrolase of Flavobacterium sp.; amidase 169398..170897 Lactococcus lactis subsp. lactis Il1403 1113774 NP_266323.1 CDS dinF NC_002662.1 170979 172319 R damage-inducible protein; adaptations and atypical conditions; similar to DinF protein from Streptococcus pneumoniae; DinF complement(170979..172319) Lactococcus lactis subsp. lactis Il1403 1113775 NP_266324.1 CDS cspE NC_002662.1 172501 172698 R adaptations and atypical conditions; cold-shock (CSD) family; cold shock protein E complement(172501..172698) Lactococcus lactis subsp. lactis Il1403 1113776 NP_266325.1 CDS ybhA NC_002662.1 172816 173349 D similar to 5-formyltetrahydrofolate cyclo-ligase; hypothetical protein 172816..173349 Lactococcus lactis subsp. lactis Il1403 1113777 NP_266326.1 CDS ybhB NC_002662.1 173339 174031 D hypothetical protein 173339..174031 Lactococcus lactis subsp. lactis Il1403 1113778 NP_266327.1 CDS ybhC NC_002662.1 174131 174562 D hypothetical protein 174131..174562 Lactococcus lactis subsp. lactis Il1403 1113779 NP_266328.1 CDS ybhD NC_002662.1 174953 176005 D hypothetical protein 174953..176005 Lactococcus lactis subsp. lactis Il1403 1113780 NP_266329.1 CDS ybhE NC_002662.1 176338 177432 D similar to outer surface protein of Borrelia burgdorferi; hypothetical protein 176338..177432 Lactococcus lactis subsp. lactis Il1403 1113781 NP_266330.1 CDS celB NC_002662.1 177530 179014 D transport and binding protein; PTS system; PTS system cellobiose-specific transporter subunit IIC 177530..179014 Lactococcus lactis subsp. lactis Il1403 1113782 NP_835290.1 CDS L200010 NC_002662.1 179139 179345 D hypothetical protein 179139..179345 Lactococcus lactis subsp. lactis Il1403 1113783 NP_266331.1 CDS bglS NC_002662.1 179668 181104 D energy metabolism, sugars; beta-glucosidase A 179668..181104 Lactococcus lactis subsp. lactis Il1403 1113784 NP_266332.1 CDS dut NC_002662.1 181168 181620 D catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 181168..181620 Lactococcus lactis subsp. lactis Il1403 1113785 NP_266333.1 CDS ybiB NC_002662.1 181873 183216 D similar to several 5'-nucleotidases; hypothetical protein 181873..183216 Lactococcus lactis subsp. lactis Il1403 1113786 NP_266334.1 CDS ybiC NC_002662.1 183231 183986 D similar to YutD of Bacillus subtilis; hypothetical protein 183231..183986 Lactococcus lactis subsp. lactis Il1403 1113787 NP_266335.1 CDS ybiD NC_002662.1 184180 185277 D 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 184180..185277 Lactococcus lactis subsp. lactis Il1403 1113788 NP_266336.1 CDS ybiE NC_002662.1 185523 186134 D aerobic energy metabolism; similar to different oxidoreductases; oxidoreductase 185523..186134 Lactococcus lactis subsp. lactis Il1403 1113789 NP_266337.1 CDS preA NC_002662.1 186285 187265 D prenyl transferase 186285..187265 Lactococcus lactis subsp. lactis Il1403 1113790 NP_266338.1 CDS ybiG NC_002662.1 187459 188364 D catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 187459..188364 Lactococcus lactis subsp. lactis Il1403 1113791 NP_266342.1 CDS ybiK NC_002662.1 189816 190016 R hypothetical protein complement(189816..190016) Lactococcus lactis subsp. lactis Il1403 1113795 NP_266343.1 CDS feoB NC_002662.1 190003 192132 R transport and binding protein, cations; GTP-driven transporter of ferrous ion; ferrous ion transport protein B complement(190003..192132) Lactococcus lactis subsp. lactis Il1403 1113796 NP_266344.2 CDS feoA NC_002662.1 192234 192710 R transport and binding protein, cations; ferrous ion transport protein A complement(192234..192710) Lactococcus lactis subsp. lactis Il1403 1113797 NP_266345.1 CDS ybjA NC_002662.1 193029 193457 D this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 193029..193457 Lactococcus lactis subsp. lactis Il1403 1113798 NP_266346.2 CDS ybjJ NC_002662.1 193587 195251 R similar to hypothetical protein YloV from Bacillus subtilis; probable kinase related to hydroxyacetone kinase, evidenced by COGnitor; hypothetical protein complement(193587..195251) Lactococcus lactis subsp. lactis Il1403 1113799 NP_266347.1 CDS ybjK NC_002662.1 195251 195619 R similar to Asp23 protein of Bacillus subtilis encoded by yloU gene; conserved hypothetical akaline shock protein; hypothetical protein complement(195251..195619) Lactococcus lactis subsp. lactis Il1403 1113800 NP_266348.1 CDS rpmB NC_002662.1 195892 196086 R required for 70S ribosome assembly; 50S ribosomal protein L28 complement(195892..196086) Lactococcus lactis subsp. lactis Il1403 1113801 NP_266349.1 CDS ybjB NC_002662.1 196222 196881 D hypothetical protein 196222..196881 Lactococcus lactis subsp. lactis Il1403 1113802 NP_266350.1 CDS rmlA NC_002662.1 197074 197943 D sugar-nucleotide biosynthesis and interconversions; glucose-1-phosphate thymidylyltransferase 197074..197943 Lactococcus lactis subsp. lactis Il1403 1113803 NP_266351.1 CDS ybjD NC_002662.1 197991 198281 D hypothetical protein 197991..198281 Lactococcus lactis subsp. lactis Il1403 1113804 NP_266352.1 CDS cpsM NC_002662.1 198350 198943 D sugar-nucleotide biosynthesis and interconversions; dTDP-4-keto-6-deoxyglucose-3,5-epimerase 198350..198943 Lactococcus lactis subsp. lactis Il1403 1113805 NP_266353.1 CDS ybjF NC_002662.1 198943 199197 D hypothetical protein 198943..199197 Lactococcus lactis subsp. lactis Il1403 1113806 NP_266354.1 CDS rmlB NC_002662.1 199239 200288 D sugar-nucleotide biosynthesis and interconversions; dTDP-glucose 4,6-dehydratase 199239..200288 Lactococcus lactis subsp. lactis Il1403 1113807 NP_266355.1 CDS rmlC NC_002662.1 200377 201276 D sugar-nucleotide biosynthesis and interconversions; dTDP-4-dehydrorhamnose reductase 200377..201276 Lactococcus lactis subsp. lactis Il1403 1113808 NP_266356.1 CDS rgpA NC_002662.1 201410 202618 D surface polysaccharides, lipopolysaccharides and antigens; rhamnosyltransferase 201410..202618 Lactococcus lactis subsp. lactis Il1403 1113809 NP_266357.1 CDS rgpB NC_002662.1 202608 203567 D surface polysaccharides, lipopolysaccharides and antigens; rhamnosyltransferase 202608..203567 Lactococcus lactis subsp. lactis Il1403 1113810 NP_266358.1 CDS rgpC NC_002662.1 203548 204357 D transport and binding protein, carbohydrates; organic alcohols and acids; probably involved in side chain formation of rhamnose-glucose polysaccharide; polysaccharide ABC transporter permease 203548..204357 Lactococcus lactis subsp. lactis Il1403 1113811 NP_266359.1 CDS rgpD NC_002662.1 204357 205553 D transport and binding protein, carbohydrates; organic alcohols and acids; probably involved in side chain formation of rhamnose-glucose polysaccharide; polysaccharide ABC transporter ATP-binding protein 204357..205553 Lactococcus lactis subsp. lactis Il1403 1113812 NP_266360.1 CDS ycaF NC_002662.1 205546 205866 D hypothetical protein 205546..205866 Lactococcus lactis subsp. lactis Il1403 1113813 NP_266361.1 CDS ycaG NC_002662.1 205908 206900 D hypothetical protein 205908..206900 Lactococcus lactis subsp. lactis Il1403 1113814 NP_266362.1 CDS rgpE NC_002662.1 206916 207890 D surface polysaccharides, lipopolysaccharides and antigens; probably involved in side chain formation of rhamnose-glucose polysaccharide; glycosyltransferase 206916..207890 Lactococcus lactis subsp. lactis Il1403 1113815 NP_266363.1 CDS rgpF NC_002662.1 207900 209669 D polysaccharide biosynthesis protein 207900..209669 Lactococcus lactis subsp. lactis Il1403 1113816 NP_266364.1 CDS ycbA NC_002662.1 209672 211216 D hypothetical protein 209672..211216 Lactococcus lactis subsp. lactis Il1403 1113817 NP_266365.1 CDS ycbB NC_002662.1 211306 212031 D surface polysaccharides, lipopolysaccharides and antigens; glycosyltransferase 211306..212031 Lactococcus lactis subsp. lactis Il1403 1113818 NP_266366.1 CDS ycbC NC_002662.1 212028 212399 D hypothetical protein 212028..212399 Lactococcus lactis subsp. lactis Il1403 1113819 NP_266367.1 CDS ycbD NC_002662.1 212383 213324 D surface polysaccharides, lipopolysaccharides and antigens; UDP-glucose 4-epimerase 212383..213324 Lactococcus lactis subsp. lactis Il1403 1113820 NP_266368.1 CDS ycbK NC_002662.1 213324 214751 D surface polysaccharides, lipopolysaccharides and antigens; polysaccharide biosynthesis export protein 213324..214751 Lactococcus lactis subsp. lactis Il1403 1113821 NP_266369.1 CDS ycbF NC_002662.1 214748 215887 D surface polysaccharides, lipopolysaccharides and antigens; LPS biosynthesis protein 214748..215887 Lactococcus lactis subsp. lactis Il1403 1113822 NP_266370.1 CDS ycbG NC_002662.1 215887 216723 D surface polysaccharides, lipopolysaccharides and antigens; similar to Cps19aG protein in LPS gene claster of Streptococcus pneumoniae; LPS biosynthesis protein 215887..216723 Lactococcus lactis subsp. lactis Il1403 1113823 NP_266371.1 CDS ycbH NC_002662.1 216713 217714 D surface polysaccharides, lipopolysaccharides and antigens; similar to many glucosyl or galactosyl transferases involved in polysaccharide biosynthesis; sugar transferase 216713..217714 Lactococcus lactis subsp. lactis Il1403 1113824 NP_266372.1 CDS ycbI NC_002662.1 217716 218573 D surface polysaccharides, lipopolysaccharides and antigens; similar to glycosyl transferases; sugar transferase 217716..218573 Lactococcus lactis subsp. lactis Il1403 1113825 NP_266373.1 CDS ycbJ NC_002662.1 218600 219826 D surface polysaccharides, lipopolysaccharides and antigens; similar to glycerol diester phosphodiesterases; LPS biosynthesis protein 218600..219826 Lactococcus lactis subsp. lactis Il1403 1113826 NP_266374.1 CDS tagD1 NC_002662.1 219837 220265 D surface polysaccharides, lipopolysaccharides and antigens; glycerol-3-phosphate cytidiltransferase 219837..220265 Lactococcus lactis subsp. lactis Il1403 1113827 NP_266375.1 CDS yccB NC_002662.1 220391 220903 R hypothetical protein complement(220391..220903) Lactococcus lactis subsp. lactis Il1403 1113828 NP_266376.1 CDS guaB NC_002662.1 221285 222766 D catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 221285..222766 Lactococcus lactis subsp. lactis Il1403 1113829 NP_266377.1 CDS yqeL NC_002662.1 222972 224117 D in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis; GTP-binding protein YqeH 222972..224117 Lactococcus lactis subsp. lactis Il1403 1113830 NP_266379.2 CDS hflX NC_002662.1 224764 226008 D GTP-binding protein; counterpart of YnbA of Bacillus subtilis and HflX of Escherichia coli; hypothetical protein 224764..226008 Lactococcus lactis subsp. lactis Il1403 1113832 NP_266380.2 CDS yccF NC_002662.1 226054 226368 D hypothetical protein 226054..226368 Lactococcus lactis subsp. lactis Il1403 1113833 NP_266381.1 CDS yccG NC_002662.1 226415 227014 D hypothetical protein 226415..227014 Lactococcus lactis subsp. lactis Il1403 1113834 NP_266382.1 CDS yccH NC_002662.1 227007 227597 D hypothetical protein 227007..227597 Lactococcus lactis subsp. lactis Il1403 1113835 NP_266383.1 CDS yccI NC_002662.1 227643 228068 D hypothetical protein 227643..228068 Lactococcus lactis subsp. lactis Il1403 1113836 NP_266384.1 CDS yccJ NC_002662.1 228234 228593 D hypothetical protein 228234..228593 Lactococcus lactis subsp. lactis Il1403 1113837 NP_266385.1 CDS yccK NC_002662.1 228693 229427 D hypothetical protein 228693..229427 Lactococcus lactis subsp. lactis Il1403 1113838 NP_266386.1 CDS yccL NC_002662.1 229477 230646 D similar to YlbM protein of Bacillus subtilis; hypothetical protein 229477..230646 Lactococcus lactis subsp. lactis Il1403 1113839 NP_266387.1 CDS ycdA NC_002662.1 230717 231142 D similar to BacF protein from Enterococcus faecalis pheromone-responsive conjugative plasmid pPD1; hypothetical protein 230717..231142 Lactococcus lactis subsp. lactis Il1403 1113840 NP_266388.1 CDS ycdB NC_002662.1 231298 232014 D similar to YeeN from E. coli; hypothetical protein 231298..232014 Lactococcus lactis subsp. lactis Il1403 1113841 NP_266389.1 CDS ycdC NC_002662.1 232081 232722 D hypothetical protein 232081..232722 Lactococcus lactis subsp. lactis Il1403 1113842 NP_266390.1 CDS ung NC_002662.1 232719 233378 D Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 232719..233378 Lactococcus lactis subsp. lactis Il1403 1113843 NP_266393.1 CDS ycdF NC_002662.1 234472 235017 D similar to tetR-family transcription regulators; transcriptional regulator 234472..235017 Lactococcus lactis subsp. lactis Il1403 1113846 NP_266394.1 CDS ycdH NC_002662.1 235128 236588 R transport and binding protein; similar to several multidrug resistance proteins; transporter complement(235128..236588) Lactococcus lactis subsp. lactis Il1403 1113847 NP_266395.1 CDS rmeC NC_002662.1 236778 237140 D MerR family of transcription regulators; transcriptional regulator 236778..237140 Lactococcus lactis subsp. lactis Il1403 1113848 NP_266396.1 CDS rpsU NC_002662.1 237226 237402 D a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 237226..237402 Lactococcus lactis subsp. lactis Il1403 1113849 NP_266397.1 CDS ycdJ NC_002662.1 237609 240020 D similar to YpiL and YigE; hypothetical protein 237609..240020 Lactococcus lactis subsp. lactis Il1403 1113850 NP_266398.1 CDS yceA NC_002662.1 240032 240631 D similar to Y39C12A.3 protein of Caenorhabditis elegans; similar to YceC, YihA and YpiF; hypothetical protein 240032..240631 Lactococcus lactis subsp. lactis Il1403 1113851 NP_266399.1 CDS yceD NC_002662.1 241256 241705 D hypothetical protein 241256..241705 Lactococcus lactis subsp. lactis Il1403 1113853 NP_266400.1 CDS yceE NC_002662.1 241794 242606 D hypothetical protein 241794..242606 Lactococcus lactis subsp. lactis Il1403 1113854 NP_266401.1 CDS pgk NC_002662.1 242796 243992 D Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 242796..243992 Lactococcus lactis subsp. lactis Il1403 1113855 NP_266402.2 CDS dhaK NC_002662.1 244069 245055 D similar to DhaK; in Lactococcus lactis this protein froms a stable complex with DhaS and activates transcription of the dha operon in the presence of dihydroxyacetone; DhaKLM operon coactivator DhaQ 244069..245055 Lactococcus lactis subsp. lactis Il1403 1113856 NP_266403.2 CDS yceG NC_002662.1 245056 245598 R helix-turn-helix from TetR family; similar to Y07639; hypothetical protein complement(245056..245598) Lactococcus lactis subsp. lactis Il1403 1113857 NP_266404.2 CDS dhaL NC_002662.1 245692 246690 D with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK 245692..246690 Lactococcus lactis subsp. lactis Il1403 1113858 NP_266405.1 CDS dhaM NC_002662.1 246700 247278 D anaerobic energy metabolism; similar to the C-terminal part of dihydroxyacetone kinase from Citrobacter freundii; dihydroxyacetone kinase 246700..247278 Lactococcus lactis subsp. lactis Il1403 1113859 NP_266406.1 CDS yceJ NC_002662.1 247275 247646 D hypothetical protein 247275..247646 Lactococcus lactis subsp. lactis Il1403 1113860 NP_266407.1 CDS glpF1 NC_002662.1 247656 248372 D transport and binding protein; carbohydrates, organic alcohols and acids; glycerol uptake facilitator 247656..248372 Lactococcus lactis subsp. lactis Il1403 1113861 NP_266408.1 CDS pepDA NC_002662.1 248411 249790 R degradation of proteins, peptides, and glycopeptides; similar to dipeptidase PepD of Lactobacillus helveticus; dipeptidase complement(248411..249790) Lactococcus lactis subsp. lactis Il1403 1113862 NP_266409.1 CDS ycfA NC_002662.1 249968 250615 D TetR/AcrR family of transcription regulators; transcriptional regulator 249968..250615 Lactococcus lactis subsp. lactis Il1403 1113863 NP_266410.1 CDS ycfB NC_002662.1 250701 251447 D transport and binding protein; ABC transporter ATP-binding protein 250701..251447 Lactococcus lactis subsp. lactis Il1403 1113864 NP_266411.1 CDS ycfC NC_002662.1 251444 252586 D transport and binding protein; ABC transporter permease 251444..252586 Lactococcus lactis subsp. lactis Il1403 1113865 NP_266412.1 CDS ycfD NC_002662.1 252684 253853 D UPF0064 family; similar to YwbD of Bacillus subtilis; hypothetical protein 252684..253853 Lactococcus lactis subsp. lactis Il1403 1113866 NP_266413.1 CDS fbp NC_002662.1 254043 255965 D gluconeogenesis; similar to fructose-1,6-bisphosphatase of Bacillus subtilis; fructose-1,6-bisphosphatase 254043..255965 Lactococcus lactis subsp. lactis Il1403 1113867 NP_266414.1 CDS ycfF NC_002662.1 256200 257471 R similar to YtfP of Bacillus subtilis; hypothetical protein complement(256200..257471) Lactococcus lactis subsp. lactis Il1403 1113868 NP_266415.1 CDS ycfG NC_002662.1 257612 258439 D UPF0031 family; hypothetical protein 257612..258439 Lactococcus lactis subsp. lactis Il1403 1113869 NP_266416.1 CDS ycfH NC_002662.1 258588 259001 D hypothetical protein 258588..259001 Lactococcus lactis subsp. lactis Il1403 1113870 NP_266417.1 CDS ycfI NC_002662.1 259172 261007 D transport and binding protein; contains two ATP binding domains; ABC transporter ATP-binding protein 259172..261007 Lactococcus lactis subsp. lactis Il1403 1113871 NP_266420.1 CDS ycgC NC_002662.1 262977 263630 D hypothetical protein 262977..263630 Lactococcus lactis subsp. lactis Il1403 1113874 NP_266421.2 CDS ycgD NC_002662.1 263676 264695 R aerobic energy metabolism; oxidoreductase complement(263676..264695) Lactococcus lactis subsp. lactis Il1403 1113875 NP_266422.1 CDS ycgE NC_002662.1 265021 265497 R catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase complement(265021..265497) Lactococcus lactis subsp. lactis Il1403 1113876 NP_266423.1 CDS ycgF NC_002662.1 265711 266175 D hypothetical protein 265711..266175 Lactococcus lactis subsp. lactis Il1403 1113877 NP_266424.1 CDS ycgG NC_002662.1 266240 267085 D aerobic energy metabolism; aldo/keto reductase family; oxidoreductase 266240..267085 Lactococcus lactis subsp. lactis Il1403 1113878 NP_266425.1 CDS ycgH NC_002662.1 267248 267763 D similar to nicotinamidase or pyrazinamidase from Mycobacterium smegmatis; amidase 267248..267763 Lactococcus lactis subsp. lactis Il1403 1113879 NP_266426.1 CDS ycgI NC_002662.1 267882 268430 D hypothetical protein 267882..268430 Lactococcus lactis subsp. lactis Il1403 1113880 NP_266427.1 CDS ycgJ NC_002662.1 268427 268711 D hypothetical protein 268427..268711 Lactococcus lactis subsp. lactis Il1403 1113881 NP_266428.1 CDS acmA NC_002662.1 268750 270069 R cell wall hydrolase; muramidase-2 like protein in Enterococcus faecalis; in Enterococcus faecalis a mutant in this gene has no effect on virulence in mouse models; Listeria monocytogenes MurA in involved in general autolysis; contains an N-terminal muramid; autolysin complement(268750..270069) Lactococcus lactis subsp. lactis Il1403 1113882 NP_266429.1 CDS nrdD NC_002662.1 270413 272656 D Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 270413..272656 Lactococcus lactis subsp. lactis Il1403 1113883 NP_266430.1 CDS nrdG NC_002662.1 272670 273269 D salvage of nucleosides and nucleotides; anaerobic ribonucleoside-triphosphate reductase activating protein 272670..273269 Lactococcus lactis subsp. lactis Il1403 1113884 NP_266431.1 CDS ychC NC_002662.1 273378 273884 R hypothetical protein complement(273378..273884) Lactococcus lactis subsp. lactis Il1403 1113885 NP_266432.1 CDS eno NC_002662.1 274176 275444 D enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 274176..275444 Lactococcus lactis subsp. lactis Il1403 1113886 NP_266433.1 CDS cbiO NC_002662.1 275743 276576 D with CbiNQ forms the ABC transporter for cobalt import; Lactococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit 275743..276576 Lactococcus lactis subsp. lactis Il1403 1113887 NP_266434.1 CDS cbiO NC_002662.1 276762 277628 D with CbiNQ forms the ABC transporter for cobalt import; Lactococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit 276762..277628 Lactococcus lactis subsp. lactis Il1403 1113888 NP_266435.1 CDS ychF NC_002662.1 277628 278428 D transport and binding protein; ABC transporter permease 277628..278428 Lactococcus lactis subsp. lactis Il1403 1113889 NP_266436.1 CDS ychG NC_002662.1 278452 279063 D similar to bacterocin transport accessory protein Bta of Streptococcus pneumoniae; maybe a part of trasport system ychDEF; hypothetical protein 278452..279063 Lactococcus lactis subsp. lactis Il1403 1113890 NP_266437.1 CDS ychH NC_002662.1 279273 280043 D similar to acetyltransferases; acetyltransferase 279273..280043 Lactococcus lactis subsp. lactis Il1403 1113891 NP_266438.1 CDS yciA NC_002662.1 280180 281334 D energy metabolism, amino acids and amines; similar to several hippurate hydrolases and amino acid amidohydrolases; may be a peptidase.; amino acid amidohydrolase 280180..281334 Lactococcus lactis subsp. lactis Il1403 1113892 NP_266439.1 CDS xynD NC_002662.1 281456 282574 D endo-1,4-beta-xylanase D 281456..282574 Lactococcus lactis subsp. lactis Il1403 1113893 NP_266440.1 CDS rpsD NC_002662.1 283758 284369 D primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 283758..284369 Lactococcus lactis subsp. lactis Il1403 1113894 NP_266441.1 CDS yciC NC_002662.1 284496 286634 D similar to ydcI of Bacillus subtilis; contains has S1 motif; similar to tex (toxin expression regulator) genes; hypothetical protein 284496..286634 Lactococcus lactis subsp. lactis Il1403 1113895 NP_266442.1 CDS yciD NC_002662.1 286731 287174 D similar to adenylate kinase; hypothetical protein 286731..287174 Lactococcus lactis subsp. lactis Il1403 1113896 NP_266443.1 CDS add NC_002662.1 287447 288505 D catalyzes the formation of inosine from adenosine; adenosine deaminase 287447..288505 Lactococcus lactis subsp. lactis Il1403 1113897 NP_266444.1 CDS yciF NC_002662.1 288537 288755 R hypothetical protein complement(288537..288755) Lactococcus lactis subsp. lactis Il1403 1113898 NP_266445.1 CDS yciG NC_002662.1 288792 289205 R hypothetical protein complement(288792..289205) Lactococcus lactis subsp. lactis Il1403 1113899 NP_266446.1 CDS yciH NC_002662.1 289409 291091 R hypothetical protein complement(289409..291091) Lactococcus lactis subsp. lactis Il1403 1113900 NP_266447.1 CDS ycjA NC_002662.1 291264 291494 R similar to ykzG Bacillus subtilis; hypothetical protein complement(291264..291494) Lactococcus lactis subsp. lactis Il1403 1113901 NP_266448.1 CDS ycjB NC_002662.1 291804 292529 D hypothetical protein 291804..292529 Lactococcus lactis subsp. lactis Il1403 1113902 NP_266449.1 CDS ycjC NC_002662.1 292483 293052 D ribosomal proteins; synthesis and modification; similar to several ribosomal-protein-alanine N-acetyltransferases; acetyltransferase 292483..293052 Lactococcus lactis subsp. lactis Il1403 1113903 NP_266450.1 CDS ycjD NC_002662.1 293057 293527 D ribosomal proteins; synthesis and modification; similar to different ribosomal-protein-alanine acetyltransferases; acetyltransferase 293057..293527 Lactococcus lactis subsp. lactis Il1403 1113904 NP_266451.1 CDS gcp NC_002662.1 293530 294570 D in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 293530..294570 Lactococcus lactis subsp. lactis Il1403 1113905 NP_266452.1 CDS ycjF NC_002662.1 294570 294770 D hypothetical protein 294570..294770 Lactococcus lactis subsp. lactis Il1403 1113906 NP_266453.1 CDS ycjG NC_002662.1 294964 295101 R hypothetical protein complement(294964..295101) Lactococcus lactis subsp. lactis Il1403 1113907 NP_266454.1 CDS ycjH NC_002662.1 295201 295989 R hypothetical protein complement(295201..295989) Lactococcus lactis subsp. lactis Il1403 1113908 NP_266455.1 CDS ycjI NC_002662.1 296289 297338 D hypothetical protein 296289..297338 Lactococcus lactis subsp. lactis Il1403 1113909 NP_266456.1 CDS phnC NC_002662.1 297457 298197 D transport and binding protein, anions; phosphonate ABC transporter ATP-binding protein 297457..298197 Lactococcus lactis subsp. lactis Il1403 1113910 NP_266457.1 CDS phnB NC_002662.1 298198 299010 D transport and binding protein, anions; phosphonate ABC transporter permease 298198..299010 Lactococcus lactis subsp. lactis Il1403 1113911 NP_266458.1 CDS phnE NC_002662.1 299025 299834 D transport and binding protein, anions; phosphonate ABC transporter permease 299025..299834 Lactococcus lactis subsp. lactis Il1403 1113912 NP_266459.1 CDS ycjM NC_002662.1 299840 301399 D nucleotide and nucleoside interconversions; similar to nucleotide phosphodiesterases and UDP-sugar hydrolases; phosphatase 299840..301399 Lactococcus lactis subsp. lactis Il1403 1113913 NP_266460.1 CDS tpx NC_002662.1 301726 302208 D adaptations and atypical conditions; antioxidant activity; may remove peroidases or hydrogen peroxide; TPX/TAGD family; thiol peroxidase 301726..302208 Lactococcus lactis subsp. lactis Il1403 1113914 NP_266461.1 CDS pepN NC_002662.1 302381 304921 D evidence experimental PMID:1352755; degradation of proteins, peptides, and glycopeptides; aminopeptidase N 302381..304921 Lactococcus lactis subsp. lactis Il1403 1113915 NP_266462.1 CDS napC NC_002662.1 304960 306153 R multidrug resistance; similar to NapC protein from Enterococcus hirae; similar to many tetracycline resistance efflux proteins of class H; multidrug-efflux transporter complement(304960..306153) Lactococcus lactis subsp. lactis Il1403 1113916 NP_266463.1 CDS napB NC_002662.1 306480 306959 R similar to NapB protein of Enterococcus hirae; MarR family transcriptional regulator complement(306480..306959) Lactococcus lactis subsp. lactis Il1403 1113917 NP_266464.1 CDS ydaE NC_002662.1 306956 308233 R transort and binding protein, cations; similar to several cation efflux system proteins; cation transporter complement(306956..308233) Lactococcus lactis subsp. lactis Il1403 1113918 NP_266465.1 CDS ydaF NC_002662.1 308509 308859 D hypothetical protein 308509..308859 Lactococcus lactis subsp. lactis Il1403 1113919 NP_266466.1 CDS ydaG NC_002662.1 309171 310892 D transport and binding protein; ABC transporter ATP-binding protein/permease 309171..310892 Lactococcus lactis subsp. lactis Il1403 1113920 NP_266467.1 CDS ydbA NC_002662.1 310896 312890 D transport and binding protein; ABC transporter ATP-binding protein/permease 310896..312890 Lactococcus lactis subsp. lactis Il1403 1113921 NP_266468.1 CDS murA1 NC_002662.1 313067 314332 D adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 313067..314332 Lactococcus lactis subsp. lactis Il1403 1113922 NP_266469.1 CDS ydbC NC_002662.1 314378 314596 D hypothetical protein 314378..314596 Lactococcus lactis subsp. lactis Il1403 1113923 NP_266470.2 CDS ydbD NC_002662.1 314623 314961 R hypothetical protein complement(314623..314961) Lactococcus lactis subsp. lactis Il1403 1113924 NP_266471.1 CDS ydbE NC_002662.1 315003 315551 R similar to BioY protein precursor of Bacillus sphaericus; hypothetical protein complement(315003..315551) Lactococcus lactis subsp. lactis Il1403 1113925 NP_266472.1 CDS ydbF NC_002662.1 315662 316138 R regulatory funcion; similar to EbsC regulator of Enterococcus faecalis; transcriptional regulator complement(315662..316138) Lactococcus lactis subsp. lactis Il1403 1113926 NP_266473.1 CDS ydbH NC_002662.1 316202 316777 R hypothetical protein complement(316202..316777) Lactococcus lactis subsp. lactis Il1403 1113927 NP_266474.1 CDS plpA NC_002662.1 317479 318339 D membranes, lipoproteins, and porins; attached to the outer membrance by a lipid anchor; NLPA family of lipoproteins; outer membrane lipoprotein 317479..318339 Lactococcus lactis subsp. lactis Il1403 1113928 NP_266475.1 CDS plpB NC_002662.1 318483 319343 D membranes, lipoproteins, and porins; attached to the outer membrance by a lipid anchor; NLPA family of lipoproteins; outer membrane lipoprotein 318483..319343 Lactococcus lactis subsp. lactis Il1403 1113929 NP_266476.1 CDS plpC NC_002662.1 319460 320320 D membranes, lipoproteins, and porins; attached to the outer membrance by a lipid anchor; NLPA family of lipoproteins; outer membrane lipoprotein 319460..320320 Lactococcus lactis subsp. lactis Il1403 1113930 NP_266477.1 CDS plpD NC_002662.1 320339 321199 D membranes, lipoproteins, and porins; attached to the outer membrance by a lipid anchor; NLPA family of lipoproteins; outer membrane lipoprotein 320339..321199 Lactococcus lactis subsp. lactis Il1403 1113931 NP_266478.1 CDS ydcB NC_002662.1 321303 322409 D transport and binding protein; amino acids, peptides and amines; amino acid ABC transporter ATP binding protein 321303..322409 Lactococcus lactis subsp. lactis Il1403 1113932 NP_266479.1 CDS ydcC NC_002662.1 322409 323104 D transport and binding protein; amino acids, peptides and amines; amino acid ABC transporter permease 322409..323104 Lactococcus lactis subsp. lactis Il1403 1113933 NP_266480.1 CDS ydcD NC_002662.1 323152 323700 D hypothetical protein 323152..323700 Lactococcus lactis subsp. lactis Il1403 1113934 NP_266481.1 CDS ydcE NC_002662.1 323809 325506 D transport and binding protein; contains two ATP-binding domains; ABC transporter ATP-binding protein 323809..325506 Lactococcus lactis subsp. lactis Il1403 1113935 NP_266482.1 CDS ydcF NC_002662.1 325499 326320 D transport and binding protein; ABC transporter permease 325499..326320 Lactococcus lactis subsp. lactis Il1403 1113936 NP_266483.1 CDS ydcG NC_002662.1 326483 326776 D PBSX(XRE) family of transcription regulators; transcriptional regulator 326483..326776 Lactococcus lactis subsp. lactis Il1403 1113937 NP_266484.1 CDS fhuB NC_002662.1 327472 328422 D transort and binding protein, cations; ferrichrome ABC transporter permease 327472..328422 Lactococcus lactis subsp. lactis Il1403 1113939 NP_266485.1 CDS fhuG NC_002662.1 328424 329362 D transort and binding protein, cations; ferrichrome ABC transporter permease 328424..329362 Lactococcus lactis subsp. lactis Il1403 1113940 NP_266486.1 CDS fhuD NC_002662.1 329447 330388 D ferrichrome ABC transporter substrate binding protein 329447..330388 Lactococcus lactis subsp. lactis Il1403 1113941 NP_266487.1 CDS fhuR NC_002662.1 330450 331355 D LysR-family regulators; probably cotranscribed with other fhu genes; fhu operon transcription regulator 330450..331355 Lactococcus lactis subsp. lactis Il1403 1113942 NP_266488.1 CDS yddA NC_002662.1 331413 332594 R transport and binding protein; transporter complement(331413..332594) Lactococcus lactis subsp. lactis Il1403 1113943 NP_266489.1 CDS yddB NC_002662.1 332607 333425 R aerobic energy metabolism; oxidoreductase complement(332607..333425) Lactococcus lactis subsp. lactis Il1403 1113944 NP_266490.1 CDS yddC NC_002662.1 333567 333914 D hypothetical protein 333567..333914 Lactococcus lactis subsp. lactis Il1403 1113945 NP_266491.1 CDS yddD NC_002662.1 333940 334332 D hypothetical protein 333940..334332 Lactococcus lactis subsp. lactis Il1403 1113946 NP_266492.1 CDS gpmA NC_002662.1 334509 335210 D 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 334509..335210 Lactococcus lactis subsp. lactis Il1403 1113947 NP_266493.1 CDS ahpC NC_002662.1 335384 335947 D cellular processes, detoxification; directly reduces organic hydroperoxides; Probably induced by heat shock, salt stress, oxidative stress and glucose limitation; general stress protein; alkyl hydroperoxide reductase 335384..335947 Lactococcus lactis subsp. lactis Il1403 1113948 NP_266494.1 CDS ahpF NC_002662.1 336014 337543 D cellular processes, detoxification; protects the cell against DNA damage by alkyl hydroperoxides; similar to NADH peroxidase nox-1 of Streptococcus mutans; alkyl hydroperoxide reductase 336014..337543 Lactococcus lactis subsp. lactis Il1403 1113949 NP_266495.1 CDS pbp2B NC_002662.1 337709 339874 D cell envelope, murein sacculus and peptidoglycan; penicillin-binding protein 2B 337709..339874 Lactococcus lactis subsp. lactis Il1403 1113950 NP_266496.1 CDS recR NC_002662.1 340013 340609 D involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 340013..340609 Lactococcus lactis subsp. lactis Il1403 1113951 NP_266497.1 CDS ddl NC_002662.1 340726 341775 D D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 340726..341775 Lactococcus lactis subsp. lactis Il1403 1113952 NP_266498.1 CDS murF NC_002662.1 341850 343172 D cell envelope murein sacculus and peptidoglycan; MURCDEF family; D-Ala-D-Ala adding enzyme 341850..343172 Lactococcus lactis subsp. lactis Il1403 1113953 NP_266499.1 CDS optS NC_002662.1 343342 344994 D transport and binding protein; amino acids, peptides and amines; oligopeptide ABC transporter substrate binding protein 343342..344994 Lactococcus lactis subsp. lactis Il1403 1113954 NP_266500.1 CDS optA NC_002662.1 345303 346940 D transport and binding protein; amino acids, peptides and amines; oligopeptide ABC transporter substrate binding protein 345303..346940 Lactococcus lactis subsp. lactis Il1403 1113955 NP_266501.1 CDS optB NC_002662.1 347018 347929 D transport and binding protein; amino acids, peptides and amines; oligopeptide ABC transporter permease 347018..347929 Lactococcus lactis subsp. lactis Il1403 1113956 NP_266502.1 CDS optC NC_002662.1 347945 348976 D transport and binding protein; amino acids, peptides and amines; oligopeptide ABC transporter permease 347945..348976 Lactococcus lactis subsp. lactis Il1403 1113957 NP_266503.1 CDS optD NC_002662.1 348979 350028 D transport and binding protein; amino acids, peptides and amines; oligopeptide ABC transporter ATP binding protein 348979..350028 Lactococcus lactis subsp. lactis Il1403 1113958 NP_266504.1 CDS optF NC_002662.1 350025 350966 D transport and binding protein; amino acids, peptides and amines; oligopeptide ABC transporter ATP binding protein 350025..350966 Lactococcus lactis subsp. lactis Il1403 1113959 NP_266505.1 CDS prfC NC_002662.1 351198 352769 D stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 351198..352769 Lactococcus lactis subsp. lactis Il1403 1113960 NP_266506.1 CDS rheA NC_002662.1 353033 354676 D RNA processing; ATP-dependent RNA-binding protein with helicase activity; similar to DEAD box family helicases; ATP-dependent RNA helicase 353033..354676 Lactococcus lactis subsp. lactis Il1403 1113961 NP_266507.1 CDS era NC_002662.1 355047 355958 D Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 355047..355958 Lactococcus lactis subsp. lactis Il1403 1113962 NP_266508.1 CDS asnB NC_002662.1 356055 357647 D functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; asparagine synthetase B 356055..357647 Lactococcus lactis subsp. lactis Il1403 1113963 NP_266509.1 CDS mutM NC_002662.1 357841 358659 D Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 357841..358659 Lactococcus lactis subsp. lactis Il1403 1113964 NP_266510.1 CDS recA NC_002662.1 358813 359976 D catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 358813..359976 Lactococcus lactis subsp. lactis Il1403 1113965 NP_266511.1 CDS ydgB NC_002662.1 359989 361362 R transport and binding protein; amino acids, peptides and amines; similar to many amino acid permeases; amino acid permease complement(359989..361362) Lactococcus lactis subsp. lactis Il1403 1113966 NP_266512.1 CDS ydgC NC_002662.1 361431 362810 R transport and binding protein; amino acids, peptides and amines; similar to many amino acid permeases; amino acid permease complement(361431..362810) Lactococcus lactis subsp. lactis Il1403 1113967 NP_266513.1 CDS ydgD NC_002662.1 362957 363337 D similar to YlbF protein of Bacillus subtilis; involved in competence and sporulation development; hypothetical protein 362957..363337 Lactococcus lactis subsp. lactis Il1403 1113968 NP_266514.1 CDS ydgE NC_002662.1 363312 363638 D similar to hypothetical YlbG protein of Bacillus subtilis; hypothetical protein 363312..363638 Lactococcus lactis subsp. lactis Il1403 1113969 NP_266515.1 CDS ydgG NC_002662.1 363868 364386 D hypothetical protein 363868..364386 Lactococcus lactis subsp. lactis Il1403 1113970 NP_266516.1 CDS ydgF NC_002662.1 364451 365044 R similar to hypothetical YjbK protein Bacillus subtilis; hypothetical protein complement(364451..365044) Lactococcus lactis subsp. lactis Il1403 1113971 NP_266517.1 CDS ydgH NC_002662.1 365261 365905 D similar to YoaT protein of Bacillus subtilis; hypothetical protein 365261..365905 Lactococcus lactis subsp. lactis Il1403 1113972 NP_266518.2 CDS ydgI NC_002662.1 366093 366752 D similar to YjbM protein of Bacillus subtilis; GTP pyrophosphokinase 366093..366752 Lactococcus lactis subsp. lactis Il1403 1113973 NP_266519.1 CDS ppnK NC_002662.1 366739 367551 D catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 366739..367551 Lactococcus lactis subsp. lactis Il1403 1113974 NP_266520.1 CDS rluE NC_002662.1 367551 368432 D RNA synthesis, modification, and DNA transcription; family 2 of pseudouridine synthases; pseudouridine synthase 367551..368432 Lactococcus lactis subsp. lactis Il1403 1113975 NP_266521.1 CDS ppiA NC_002662.1 368474 369304 R translation; protein modification; peptidyl-prolyl cis-trans isomerase complement(368474..369304) Lactococcus lactis subsp. lactis Il1403 1113976 NP_266522.1 CDS lysQ NC_002662.1 369615 371048 D transport and binding protein; amino acids, peptides and amines; there is another lysine specific permease LysP; lysine specific permease 369615..371048 Lactococcus lactis subsp. lactis Il1403 1113977 NP_266523.1 CDS ydhB NC_002662.1 371163 371975 D hypothetical protein 371163..371975 Lactococcus lactis subsp. lactis Il1403 1113978 NP_266524.1 CDS ydhC NC_002662.1 371975 372952 D similar to hypothetical protein TP0796 Treponema pallidum; hypothetical protein 371975..372952 Lactococcus lactis subsp. lactis Il1403 1113979 NP_266525.1 CDS ydhD NC_002662.1 373134 373424 D transposon related function; hypothetical protein 373134..373424 Lactococcus lactis subsp. lactis Il1403 1113980 NP_266526.1 CDS tra904D NC_002662.1 373520 374281 D evidence experimental PMID:1328163; transposon related function; IS3/IS150/IS904 family transposase; transposase of IS904D 373520..374281 Lactococcus lactis subsp. lactis Il1403 1113981 NP_266527.1 CDS ydhE NC_002662.1 374338 374895 D transposon related function; hypothetical protein 374338..374895 Lactococcus lactis subsp. lactis Il1403 1113982 NP_266528.1 CDS tra1077C NC_002662.1 374892 375710 D evidence experimental PMID:1328163; transposon related function; IS3/IS150/IS904 family transposase; IS1077C transposase 374892..375710 Lactococcus lactis subsp. lactis Il1403 1113983 NP_266529.1 CDS lysS NC_002662.1 375784 377268 R class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(375784..377268) Lactococcus lactis subsp. lactis Il1403 1113984 NP_266530.1 CDS rlrG NC_002662.1 377467 378285 R LysR-family regulators; LysR family transcriptional regulator complement(377467..378285) Lactococcus lactis subsp. lactis Il1403 1113985 NP_266531.1 CDS ydhF NC_002662.1 378449 379444 D hypothetical protein 378449..379444 Lactococcus lactis subsp. lactis Il1403 1113986 NP_266532.1 CDS ldhB NC_002662.1 379657 380601 R glycolysis; similar to malate dehydrogenase; L-lactate dehydrogenase complement(379657..380601) Lactococcus lactis subsp. lactis Il1403 1113987 NP_266533.1 CDS rlrD NC_002662.1 380895 381716 R LysR-family regulators; LysR family transcriptional regulator complement(380895..381716) Lactococcus lactis subsp. lactis Il1403 1113988 NP_266534.1 CDS ydiA NC_002662.1 381871 382845 D similar to exfoliative toxin A; transport and binding protein; tellurite resistance protein or related permease; permease 381871..382845 Lactococcus lactis subsp. lactis Il1403 1113989 NP_266535.1 CDS ydiB NC_002662.1 383134 384354 D Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 383134..384354 Lactococcus lactis subsp. lactis Il1403 1113990 NP_266536.1 CDS ydiC NC_002662.1 384568 385971 D transport and binding protein; multidrug resistance; efflux pump antibiotic resistance protein 384568..385971 Lactococcus lactis subsp. lactis Il1403 1113991 NP_266537.1 CDS ydiD NC_002662.1 386132 386737 D fatty acid and phospholipid metabolism; ACP phosphodiesterase 386132..386737 Lactococcus lactis subsp. lactis Il1403 1113992 NP_266538.1 CDS ydiE NC_002662.1 386834 387268 D hypothetical protein 386834..387268 Lactococcus lactis subsp. lactis Il1403 1113993 NP_266539.1 CDS ydiF NC_002662.1 387304 389346 R transort and binding protein, cations; Na+/H+ antiporter complement(387304..389346) Lactococcus lactis subsp. lactis Il1403 1113994 NP_266540.1 CDS ydiG NC_002662.1 389437 389907 R hypothetical protein complement(389437..389907) Lactococcus lactis subsp. lactis Il1403 1113995 NP_266541.1 CDS tyrS NC_002662.1 390031 391290 R catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase complement(390031..391290) Lactococcus lactis subsp. lactis Il1403 1113996 NP_266542.1 CDS pbp1B NC_002662.1 391435 393840 D cell envelope, murein sacculus and peptidoglycan; penicillin-binding protein 1B 391435..393840 Lactococcus lactis subsp. lactis Il1403 1113997 NP_266543.1 CDS pepA NC_002662.1 393898 394965 R evidence experimental PMID:8535515; degradation of proteins, peptides, and glycopeptides; glutamyl aminopeptidase complement(393898..394965) Lactococcus lactis subsp. lactis Il1403 1113998 NP_266544.1 CDS ydjB NC_002662.1 395161 395352 D hypothetical protein 395161..395352 Lactococcus lactis subsp. lactis Il1403 1113999 NP_266545.1 CDS trxH NC_002662.1 395394 395711 D thioredoxin, glutaredoxin, and glutathione; similar to the thioredoxin H-type from plants; thioredoxin H-type 395394..395711 Lactococcus lactis subsp. lactis Il1403 1114000 NP_266546.1 CDS ydjD NC_002662.1 395797 396423 D similar to YtpR of Bacillus subtilis and phenylalanine tRNA ligase; hypothetical protein 395797..396423 Lactococcus lactis subsp. lactis Il1403 1114001 NP_266547.1 CDS noxE NC_002662.1 396586 397926 D aerobic energy metabolism; NADH oxidase 396586..397926 Lactococcus lactis subsp. lactis Il1403 1114002 NP_266548.1 CDS ssbA NC_002662.1 398016 398405 D binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 398016..398405 Lactococcus lactis subsp. lactis Il1403 1114003 NP_266549.1 CDS groES NC_002662.1 398525 398809 D 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 398525..398809 Lactococcus lactis subsp. lactis Il1403 1114004 NP_266550.1 CDS groEL NC_002662.1 398897 400525 D 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 398897..400525 Lactococcus lactis subsp. lactis Il1403 1114005 NP_266551.1 CDS yeaA NC_002662.1 400571 401383 R similar to yycJ Bacillus subtilis; hypothetical protein complement(400571..401383) Lactococcus lactis subsp. lactis Il1403 1114006 NP_266552.1 CDS kinC NC_002662.1 401554 402996 R evidence experimental PMID:9172368; two-component systems; sensor protein kinase complement(401554..402996) Lactococcus lactis subsp. lactis Il1403 1114007 NP_266553.1 CDS llrC NC_002662.1 402989 403690 R evidence experimental PMID:10708382; two-component systems; involved in acid stress resistance development; two-component system regulator complement(402989..403690) Lactococcus lactis subsp. lactis Il1403 1114008 NP_266554.1 CDS tmk NC_002662.1 403868 404503 D catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 403868..404503 Lactococcus lactis subsp. lactis Il1403 1114009 NP_266555.1 CDS holB NC_002662.1 404636 405496 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA.; DNA polymerase III subunit delta' 404636..405496 Lactococcus lactis subsp. lactis Il1403 1114010 NP_266556.1 CDS yeaC NC_002662.1 405548 406330 D hypothetical protein 405548..406330 Lactococcus lactis subsp. lactis Il1403 1114011 NP_266557.1 CDS yeaD NC_002662.1 406323 406649 D in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA; DNA replication intiation control protein YabA 406323..406649 Lactococcus lactis subsp. lactis Il1403 1114012 NP_266558.2 CDS yeaE NC_002662.1 406649 407524 D hypothetical protein 406649..407524 Lactococcus lactis subsp. lactis Il1403 1114013 NP_266559.1 CDS yeaF NC_002662.1 407601 407792 R hypothetical protein complement(407601..407792) Lactococcus lactis subsp. lactis Il1403 1114014 NP_266560.1 CDS yeaG NC_002662.1 407855 408787 R fatty acid and phospholipid metabolism; mevalonate kinase complement(407855..408787) Lactococcus lactis subsp. lactis Il1403 1114015 NP_266561.1 CDS yeaH NC_002662.1 409093 410049 D fatty acid and phospholipid metabolism; diphosphomevalonate decarboxylase 409093..410049 Lactococcus lactis subsp. lactis Il1403 1114016 NP_266562.1 CDS yebA NC_002662.1 410036 411025 D fatty acid and phospholipid metabolism; mevalonate kinase 410036..411025 Lactococcus lactis subsp. lactis Il1403 1114017 NP_266563.1 CDS yebB NC_002662.1 411078 412121 D catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate; isopentenyl pyrophosphate isomerase 411078..412121 Lactococcus lactis subsp. lactis Il1403 1114018 NP_266564.1 CDS sodA NC_002662.1 412279 412899 D evidence experimental PMID:7665513; cellular processes, detoxification; superoxide dismutase 412279..412899 Lactococcus lactis subsp. lactis Il1403 1114019 NP_266565.1 CDS cstA NC_002662.1 413148 415502 D adaptations and atypical conditions; peptide utilization during carbon starvation; carbon starvation protein 413148..415502 Lactococcus lactis subsp. lactis Il1403 1114020 NP_266566.1 CDS rheB NC_002662.1 415804 417144 D RNA processing; ATP-dependent RNA-binding protein with helicase activity; similar to other DEAD box family helicases; ATP-dependent RNA helicase 415804..417144 Lactococcus lactis subsp. lactis Il1403 1114021 NP_266567.1 CDS yebE NC_002662.1 417148 417732 D hypothetical protein 417148..417732 Lactococcus lactis subsp. lactis Il1403 1114022 NP_266568.1 CDS yebF NC_002662.1 417888 418634 D RpiR family of transcription regulators; transcriptional regulator 417888..418634 Lactococcus lactis subsp. lactis Il1403 1114023 NP_266569.1 CDS ptcB NC_002662.1 418876 419202 D transport and binding protein; PTS system; PTS system cellobiose-specific transporter subunit IIB 418876..419202 Lactococcus lactis subsp. lactis Il1403 1114024 NP_266570.1 CDS ptcA NC_002662.1 419287 419637 D transport and binding protein; PTS system; PTS system cellobiose-specific transporter subunit IIA 419287..419637 Lactococcus lactis subsp. lactis Il1403 1114025 NP_266571.1 CDS yecA NC_002662.1 419728 420459 D RpiR family of transcription regulators; transcriptional regulator 419728..420459 Lactococcus lactis subsp. lactis Il1403 1114026 NP_835291.1 CDS L200013 NC_002662.1 420751 420945 D hypothetical protein 420751..420945 Lactococcus lactis subsp. lactis Il1403 1114027 NP_266572.1 CDS ptcC NC_002662.1 420905 422074 D transport and binding protein; PTS system; PTS system cellobiose-specific transporter subunit IIC 420905..422074 Lactococcus lactis subsp. lactis Il1403 1114028 NP_266573.1 CDS celA NC_002662.1 422156 423592 D converts 6-phospho-beta-D-glucosyl-(1,4)-D-glucose to glucose and glucose 6-phosphate; required for cellobiose uptake and metabolism; 6-phospho-beta-glucosidase 422156..423592 Lactococcus lactis subsp. lactis Il1403 1114029 NP_266574.1 CDS yecD NC_002662.1 423878 424159 D hypothetical protein 423878..424159 Lactococcus lactis subsp. lactis Il1403 1114030 NP_266575.1 CDS ligA NC_002662.1 424521 426485 D this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 424521..426485 Lactococcus lactis subsp. lactis Il1403 1114031 NP_266576.1 CDS yecE NC_002662.1 426638 427666 D similar to YegS from E. coli; lipid kinase 426638..427666 Lactococcus lactis subsp. lactis Il1403 1114032 NP_266577.1 CDS msmK NC_002662.1 427883 429019 D transport and binding protein, carbohydrates; organic alcohols and acids; multiple sugar ABC transporter ATP-binding protein 427883..429019 Lactococcus lactis subsp. lactis Il1403 1114033 NP_266578.1 CDS nifJ NC_002662.1 429327 432899 D electron transport; oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin which reduces nitrogenase; pyruvate-flavodoxin oxidoreductase 429327..432899 Lactococcus lactis subsp. lactis Il1403 1114034 NP_266579.1 CDS yedA NC_002662.1 433205 434083 D hypothetical protein 433205..434083 Lactococcus lactis subsp. lactis Il1403 1114035 NP_266580.1 CDS glmM NC_002662.1 435077 436435 D catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 435077..436435 Lactococcus lactis subsp. lactis Il1403 1114036 NP_266581.1 CDS rgrA NC_002662.1 436511 437227 R GntR family transcriptional regulator complement(436511..437227) Lactococcus lactis subsp. lactis Il1403 1114037 NP_266582.1 CDS yedE NC_002662.1 437338 437823 D similar to C part of PTS protein; hypothetical protein 437338..437823 Lactococcus lactis subsp. lactis Il1403 1114038 NP_266583.2 CDS yedF NC_002662.1 437921 439525 D transport and binding protein; PTS system; PTS system beta-glucoside-specific transporter subunit IIABC 437921..439525 Lactococcus lactis subsp. lactis Il1403 1114039 NP_266584.1 CDS yeeA NC_002662.1 439593 441902 D similar to Lactococcus lactis ATCC 19435 protein Y18267; hypothetical protein 439593..441902 Lactococcus lactis subsp. lactis Il1403 1114040 NP_266585.1 CDS pgmB NC_002662.1 442048 442713 D evidence experimental PMID:9084169; glycolysis; beta-phosphoglucomutase 442048..442713 Lactococcus lactis subsp. lactis Il1403 1114041 NP_266586.1 CDS yeeB NC_002662.1 442772 443578 R energy metabolism, sugars; similar to beta-1,4-D-xylanase of Butyrivibrio fibrisolvens; sugar hydrolase complement(442772..443578) Lactococcus lactis subsp. lactis Il1403 1114042 NP_266587.1 CDS yeeC NC_002662.1 443651 444346 D hypothetical protein 443651..444346 Lactococcus lactis subsp. lactis Il1403 1114043 NP_266588.1 CDS yeeD NC_002662.1 444288 444488 D hypothetical protein 444288..444488 Lactococcus lactis subsp. lactis Il1403 1114044 NP_266589.1 CDS yeeE NC_002662.1 444575 445000 D hypothetical protein 444575..445000 Lactococcus lactis subsp. lactis Il1403 1114045 NP_266590.1 CDS yeeF NC_002662.1 444997 445515 D hypothetical protein 444997..445515 Lactococcus lactis subsp. lactis Il1403 1114046 NP_266591.1 CDS yeeG NC_002662.1 445619 447004 D belongs to LytR family; transcriptional regulator 445619..447004 Lactococcus lactis subsp. lactis Il1403 1114047 NP_266592.1 CDS pi101 NC_002662.1 447236 448369 R prophage pi1 protein 01; similar to integrase of Lactococcus lactis phage BK5-T; integrase complement(447236..448369) Lactococcus lactis subsp. lactis Il1403 1114048 NP_266593.1 CDS pi102 NC_002662.1 448492 449070 R similar to orf3 of Lactococcus lactis phage TP901-1; prophage pi1 protein 02 complement(448492..449070) Lactococcus lactis subsp. lactis Il1403 1114049 NP_266594.1 CDS pi103 NC_002662.1 449154 449990 R transcription regulator; evidence experimental PMID:8730874; similar to the repressor protein Rro of Lactococcus lactis phage r1t. cI type regulator; prophage pi1 protein 03 complement(449154..449990) Lactococcus lactis subsp. lactis Il1403 1114050 NP_266595.1 CDS pi104 NC_002662.1 450207 450389 D transcription regulator; similar to BK5-T phage repressor protein Cro; prophage pi1 protein 04 450207..450389 Lactococcus lactis subsp. lactis Il1403 1114051 NP_266596.1 CDS pi105 NC_002662.1 450421 450654 D prophage pi1 protein 05 450421..450654 Lactococcus lactis subsp. lactis Il1403 1114052 NP_266597.1 CDS pi106 NC_002662.1 450763 450912 D prophage pi1 protein 06 450763..450912 Lactococcus lactis subsp. lactis Il1403 1114053 NP_266598.1 CDS pi107 NC_002662.1 451007 451414 D similar to tec gene product of bacteriophage r1t; prophage pi1 protein 07 451007..451414 Lactococcus lactis subsp. lactis Il1403 1114054 NP_266599.1 CDS pi108 NC_002662.1 451426 452181 D similar to orf5 of the phage r1t; prophage pi1 protein 08 451426..452181 Lactococcus lactis subsp. lactis Il1403 1114055 NP_266600.1 CDS pi109 NC_002662.1 452194 452523 D similar to orf6 of bacteriophage r1t; prophage pi1 protein 09 452194..452523 Lactococcus lactis subsp. lactis Il1403 1114056 NP_835292.1 CDS L200014 NC_002662.1 452524 452694 D hypothetical protein 452524..452694 Lactococcus lactis subsp. lactis Il1403 1114057 NP_266601.1 CDS pi110 NC_002662.1 452738 452911 D transcription regulator; similar to orf8 of bacteriophage r1t, similar to Cro repressor protein of the phage BK5-T; prophage pi1 protein 10 452738..452911 Lactococcus lactis subsp. lactis Il1403 1114058 NP_266602.1 CDS pi111 NC_002662.1 453010 453816 D prophage pi1 protein 11; similar to a recombinase of the Listeria monocytogenes bacteriophage A118; recombinase 453010..453816 Lactococcus lactis subsp. lactis Il1403 1114059 NP_266603.1 CDS pi112 NC_002662.1 453816 454592 D prophage pi1 protein 12 453816..454592 Lactococcus lactis subsp. lactis Il1403 1114060 NP_266604.2 CDS pi113 NC_002662.1 454820 455596 D prophage pi1 protein 13; similar to a replisome organiser protein Rep2009 of the bacteriophage Tuc2009; replisome organizer 454820..455596 Lactococcus lactis subsp. lactis Il1403 1114061 NP_266605.2 CDS pi114 NC_002662.1 455606 456490 D prophage pi1 protein 14; similar to the orf12 of the phage r1t; functional equivalent to DnaC of Escherichia coli or DnaI of Bacillus subtilis, which are required for chromosomal replication; DNA replication protein 455606..456490 Lactococcus lactis subsp. lactis Il1403 1114062 NP_835293.1 CDS L200015 NC_002662.1 456487 456651 D similar to bacteriophage bIL309 Orf16; hypothetical protein 456487..456651 Lactococcus lactis subsp. lactis Il1403 1114063 NP_266606.1 CDS pi115 NC_002662.1 456575 457051 D prophage pi1 protein 15 456575..457051 Lactococcus lactis subsp. lactis Il1403 1114064 NP_835294.1 CDS L200016 NC_002662.1 457159 457323 D similar to bacteriophage bIL309 Orf18; hypothetical protein 457159..457323 Lactococcus lactis subsp. lactis Il1403 1114065 NP_266607.1 CDS pi116 NC_002662.1 457298 457660 D similar to orf18 of bacteriophage r1t; prophage pi1 protein 16 457298..457660 Lactococcus lactis subsp. lactis Il1403 1114066 NP_266608.1 CDS pi117 NC_002662.1 457854 458060 D prophage pi1 protein 17 457854..458060 Lactococcus lactis subsp. lactis Il1403 1114067 NP_266609.1 CDS pi118 NC_002662.1 458053 458325 D prophage pi1 protein 18 458053..458325 Lactococcus lactis subsp. lactis Il1403 1114068 NP_266610.1 CDS pi119 NC_002662.1 458322 458876 D similar to orf24 of the bacteriophage Tuc2009; prophage pi1 protein 19 458322..458876 Lactococcus lactis subsp. lactis Il1403 1114069 NP_266611.1 CDS pi120 NC_002662.1 458873 459292 D prophage pi1 protein 16; de novo synthesis of thymidylate; similar to dUTPase of bacteriophage r1t; deoxyuridine 5'-triphosphate nucleotidohydrolase 458873..459292 Lactococcus lactis subsp. lactis Il1403 1114070 NP_266612.1 CDS pi121 NC_002662.1 459292 459582 D prophage pi1 protein 21 459292..459582 Lactococcus lactis subsp. lactis Il1403 1114071 NP_266613.1 CDS pi122 NC_002662.1 459579 459743 D similar to orf17 of bacteriophage o1205; prophage pi1 protein 22 459579..459743 Lactococcus lactis subsp. lactis Il1403 1114072 NP_835295.1 CDS L200017 NC_002662.1 459792 459935 D similar to bacteriophage bIL309 Orf27; hypothetical protein 459792..459935 Lactococcus lactis subsp. lactis Il1403 1114073 NP_266614.1 CDS pi123 NC_002662.1 459932 460114 D similar to orfx from lactococcal bacteriophage 712; prophage pi1 protein 23 459932..460114 Lactococcus lactis subsp. lactis Il1403 1114074 NP_835296.1 CDS L200018 NC_002662.1 460181 460288 D hypothetical protein 460181..460288 Lactococcus lactis subsp. lactis Il1403 1114075 NP_266615.1 CDS pi124 NC_002662.1 460296 460481 D prophage pi1 protein 24 460296..460481 Lactococcus lactis subsp. lactis Il1403 1114076 NP_266616.1 CDS pi125 NC_002662.1 460534 460743 R prophage pi1 protein 25 complement(460534..460743) Lactococcus lactis subsp. lactis Il1403 1114077 NP_266617.1 CDS pi126 NC_002662.1 460956 461249 D similar to orf4 of abiN locus from Lactococcus lactis S114 accession number Y11901; prophage pi1 protein 26 460956..461249 Lactococcus lactis subsp. lactis Il1403 1114078 NP_266618.1 CDS pi127 NC_002662.1 461360 461605 D similar to Orf20 of S.thermophilus bacteriophage o1205; prophage pi1 protein 27 461360..461605 Lactococcus lactis subsp. lactis Il1403 1114079 NP_266619.1 CDS pi128 NC_002662.1 461650 462039 D similar to orf4 of abiN locus from Lactococcus lactis S114 accession number Y11901; prophage pi1 protein 28 461650..462039 Lactococcus lactis subsp. lactis Il1403 1114080 NP_266620.1 CDS pi129 NC_002662.1 462041 462439 D similar to the 64 protein (GP64) from Mycobacteriophage l5; prophage pi1 protein 29 462041..462439 Lactococcus lactis subsp. lactis Il1403 1114081 NP_266621.1 CDS pi130 NC_002662.1 462436 462588 D prophage pi1 protein 30 462436..462588 Lactococcus lactis subsp. lactis Il1403 1114082 NP_266622.1 CDS pi131 NC_002662.1 462765 463187 D similar to orf6 of abiN locus from Lactococcus lactis S114 accession number Y11901; prophage pi1 protein 31 462765..463187 Lactococcus lactis subsp. lactis Il1403 1114083 NP_266623.2 CDS pi132 NC_002662.1 463425 463928 D prophage pi1 protein 32 463425..463928 Lactococcus lactis subsp. lactis Il1403 1114084 NP_266624.1 CDS pi133 NC_002662.1 464045 464497 D prophage pi1 protein 33; similar to small subunit (orf152 gp) of terminase from Streptococcus thermophilus bacteriophage Sfi21; terminase small subunit 464045..464497 Lactococcus lactis subsp. lactis Il1403 1114085 NP_266625.1 CDS pi134 NC_002662.1 464497 466311 D prophage pi1 protein 34; similar to large subunit (orf623 gp) of terminase from Streptococcus thermophilus bacteriophage Sfi21; terminase large subunit 464497..466311 Lactococcus lactis subsp. lactis Il1403 1114086 NP_835297.1 CDS L200019 NC_002662.1 466320 466484 D similar to bacteriophage bIL309 Orf40; hypothetical protein 466320..466484 Lactococcus lactis subsp. lactis Il1403 1114087 NP_266626.1 CDS pi135 NC_002662.1 466481 467560 D similar to a hypothetical protein of Lactobacillus bacteriophage phi adh accession number AJ131519; prophage pi1 protein 35 466481..467560 Lactococcus lactis subsp. lactis Il1403 1114088 NP_266627.1 CDS pi136 NC_002662.1 467560 468147 D prophage pi1 protein 36; similar to orf26 of Bacillus subtilis bacteriophage phi-105; prohead protease 467560..468147 Lactococcus lactis subsp. lactis Il1403 1114089 NP_266628.1 CDS pi137 NC_002662.1 468137 469450 D prophage pi1 protein 37; similar to orf27 of Bacillus subtilis bacteriophage phi-105, encoding capsid protein; capsid protein 468137..469450 Lactococcus lactis subsp. lactis Il1403 1114090 NP_266629.1 CDS pi138 NC_002662.1 469461 469766 D prophage pi1 protein 38 469461..469766 Lactococcus lactis subsp. lactis Il1403 1114091 NP_266630.1 CDS pi139 NC_002662.1 469753 470088 D similar to head-tail joining protein (orf10) of Streptococcus thermophilus bacteriophage DT1; prophage pi1 protein 39 469753..470088 Lactococcus lactis subsp. lactis Il1403 1114092 NP_266631.1 CDS pi140 NC_002662.1 470085 470570 D tail component; similar to tail component protein (Orf11) of Streptococcus thermophilus bacteriophage DT1; prophage pi1 protein 40 470085..470570 Lactococcus lactis subsp. lactis Il1403 1114093 NP_266632.1 CDS pi141 NC_002662.1 470567 470962 D tail component; similar to a tail component protein (Orf12) of Streptococcus thermophilus bacteriophage DT1; prophage pi1 protein 41 470567..470962 Lactococcus lactis subsp. lactis Il1403 1114094 NP_266633.1 CDS pi142 NC_002662.1 470964 471569 D prophage pi1 protein 42; similar to small major structural protein of Streptococcus thermophilus phage phi7201 accession number AF001793); small major structural protein 470964..471569 Lactococcus lactis subsp. lactis Il1403 1114095 NP_266634.1 CDS pi143 NC_002662.1 471629 471973 D prophage pi1 protein 43 471629..471973 Lactococcus lactis subsp. lactis Il1403 1114096 NP_266635.1 CDS pi144 NC_002662.1 472143 475982 D tail component; similar to tail component protein (Orf15) of Streptococcus thermophilus bacteriophage DT1; prophage pi1 protein 44 472143..475982 Lactococcus lactis subsp. lactis Il1403 1114097 NP_266636.1 CDS pi145 NC_002662.1 475985 477520 D tail component; similar to tail component protein (Orf17) of Streptococcus thermophilus bacteriophage DT1; prophage pi1 protein 45 475985..477520 Lactococcus lactis subsp. lactis Il1403 1114098 NP_266637.1 CDS pi146 NC_002662.1 477520 481845 D tail component; similar to tail-host specificity protein (Orf18) of Streptococcus thermophilus bacteriophage DT1; prophage pi1 protein 46 477520..481845 Lactococcus lactis subsp. lactis Il1403 1114099 NP_266638.1 CDS pi147 NC_002662.1 481865 482191 D hypothetical protein 481865..482191 Lactococcus lactis subsp. lactis Il1403 1114100 NP_266639.1 CDS pi148 NC_002662.1 482178 482465 D similar to holin of Staphylococcus aureus bacteriophage phi PVL, similar to orf95 of Lactococcus lactis phage BK5-T; prophage pi1 protein 48 482178..482465 Lactococcus lactis subsp. lactis Il1403 1114101 NP_266640.1 CDS pi149 NC_002662.1 482465 483244 D prophage pi1 protein 49; similar to orf259 of Lactococcus lactis phage BK5-T; muramidase 482465..483244 Lactococcus lactis subsp. lactis Il1403 1114102 NP_266641.1 CDS yeiD NC_002662.1 483349 483552 R hypothetical protein complement(483349..483552) Lactococcus lactis subsp. lactis Il1403 1114103 NP_266642.1 CDS truA NC_002662.1 484226 484987 D mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 484226..484987 Lactococcus lactis subsp. lactis Il1403 1114104 NP_266643.1 CDS thiD2 NC_002662.1 485020 485808 D catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 485020..485808 Lactococcus lactis subsp. lactis Il1403 1114105 NP_266644.1 CDS yeiE NC_002662.1 485857 486348 D hypothetical protein 485857..486348 Lactococcus lactis subsp. lactis Il1403 1114106 NP_266645.1 CDS yeiF NC_002662.1 486329 486871 D similar to YwlG protein from Bacillus subtilis; hypothetical protein 486329..486871 Lactococcus lactis subsp. lactis Il1403 1114107 NP_266646.1 CDS yeiG NC_002662.1 486872 488008 D energy metabolism; similar to several amino acid aminotransferases; YeiG 486872..488008 Lactococcus lactis subsp. lactis Il1403 1114108 NP_266647.1 CDS pyrG NC_002662.1 488243 489850 D CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 488243..489850 Lactococcus lactis subsp. lactis Il1403 1114109 NP_266648.1 CDS yejC NC_002662.1 490934 491806 R hypothetical protein complement(490934..491806) Lactococcus lactis subsp. lactis Il1403 1114111 NP_266649.1 CDS yejD NC_002662.1 492452 492931 R hypothetical protein complement(492452..492931) Lactococcus lactis subsp. lactis Il1403 1114112 YP_008998700.1 CDS dukA NC_002662.1 493469 494122 R deoxynucleoside kinase complement(493469..494122) Lactococcus lactis subsp. lactis Il1403 1114114 NP_266652.1 CDS dnaE NC_002662.1 494602 497784 D Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria.; DNA polymerase III DnaE 494602..497784 Lactococcus lactis subsp. lactis Il1403 1114115 NP_266653.1 CDS hly NC_002662.1 497815 498468 R cell killing; hemolysin like protein complement(497815..498468) Lactococcus lactis subsp. lactis Il1403 1114116 NP_266654.1 CDS yejH NC_002662.1 498649 499506 D similar to DegV of Bacillus subtilis; hypothetical protein 498649..499506 Lactococcus lactis subsp. lactis Il1403 1114117 NP_266655.2 CDS yejI NC_002662.1 499499 500359 D hypothetical protein 499499..500359 Lactococcus lactis subsp. lactis Il1403 1114118 NP_266656.1 CDS yejJ NC_002662.1 500356 501567 D similar to glycosyl hyrolases; hypothetical protein 500356..501567 Lactococcus lactis subsp. lactis Il1403 1114119 NP_266657.1 CDS yfaA NC_002662.1 501577 502233 D hypothetical protein 501577..502233 Lactococcus lactis subsp. lactis Il1403 1114120 NP_266658.1 CDS hslA NC_002662.1 502338 502613 D DNA replication, restriction, modification, recombination, and repair; HU like DNA-binding protein 502338..502613 Lactococcus lactis subsp. lactis Il1403 1114121 NP_266659.1 CDS ps201 NC_002662.1 502723 503871 R prophage ps2 protein 01; integrase complement(502723..503871) Lactococcus lactis subsp. lactis Il1403 1114122 NP_266660.1 CDS ps202 NC_002662.1 503995 504486 R prophage ps2 protein 02 complement(503995..504486) Lactococcus lactis subsp. lactis Il1403 1114123 NP_266661.1 CDS ps203 NC_002662.1 504540 504836 R prophage ps2 protein 03 complement(504540..504836) Lactococcus lactis subsp. lactis Il1403 1114124 NP_266662.1 CDS ps204 NC_002662.1 504883 505470 R similar to gp17v protein of Escherichia coli bacteriophage KVP40; prophage ps2 protein 04 complement(504883..505470) Lactococcus lactis subsp. lactis Il1403 1114125 NP_266663.1 CDS ps205 NC_002662.1 505482 505850 R prophage ps2 protein 05; similar to Rad protein of Lactobacillus bacteriophage phi adh; transcription repressor complement(505482..505850) Lactococcus lactis subsp. lactis Il1403 1114126 NP_266664.1 CDS ps206 NC_002662.1 506144 506335 D similar to Orf65a of Lactobacillus bacteriophage phi adh; prophage ps2 protein 06 506144..506335 Lactococcus lactis subsp. lactis Il1403 1114127 NP_266665.1 CDS ps207 NC_002662.1 506351 506611 D prophage ps2 protein 07; similar to excisionase of Streptococcus pneumoniae transposon Tn5252; excisionase 506351..506611 Lactococcus lactis subsp. lactis Il1403 1114128 NP_266666.1 CDS ps208 NC_002662.1 506770 506964 D prophage ps2 protein 08 506770..506964 Lactococcus lactis subsp. lactis Il1403 1114129 NP_266667.1 CDS ps209 NC_002662.1 506969 507394 D prophage ps2 protein 09 506969..507394 Lactococcus lactis subsp. lactis Il1403 1114130 NP_266668.1 CDS ps210 NC_002662.1 507429 507668 D prophage ps2 protein 10 507429..507668 Lactococcus lactis subsp. lactis Il1403 1114131 NP_266669.1 CDS ps211 NC_002662.1 507665 507919 D prophage ps2 protein 11 507665..507919 Lactococcus lactis subsp. lactis Il1403 1114132 NP_266670.1 CDS ps212 NC_002662.1 507916 508110 D prophage ps2 protein 12 507916..508110 Lactococcus lactis subsp. lactis Il1403 1114133 NP_266671.1 CDS ps213 NC_002662.1 508097 508423 D prophage ps2 protein 13 508097..508423 Lactococcus lactis subsp. lactis Il1403 1114134 NP_266672.1 CDS ps214 NC_002662.1 508431 509009 D prophage ps2 protein 14 508431..509009 Lactococcus lactis subsp. lactis Il1403 1114135 NP_266673.1 CDS ps215 NC_002662.1 509002 510444 D similar to Orf11 of Staphlococcus aureus transposon Tn557; prophage ps2 protein 15 509002..510444 Lactococcus lactis subsp. lactis Il1403 1114136 NP_266674.1 CDS ps216 NC_002662.1 510596 511180 D prophage ps2 protein 16 510596..511180 Lactococcus lactis subsp. lactis Il1403 1114137 NP_266675.1 CDS yfbB NC_002662.1 511357 511542 D hypothetical protein 511357..511542 Lactococcus lactis subsp. lactis Il1403 1114138 NP_266676.1 CDS ps218 NC_002662.1 511569 512177 D prophage ps2 protein 18 511569..512177 Lactococcus lactis subsp. lactis Il1403 1114139 NP_266677.1 CDS ps219 NC_002662.1 512186 512776 D similar to Orf26 of Bacillus subtilis bacteriophage phi-105; prophage ps2 protein 19 512186..512776 Lactococcus lactis subsp. lactis Il1403 1114140 NP_266678.1 CDS ps220 NC_002662.1 512992 513321 D prophage ps2 protein 20 512992..513321 Lactococcus lactis subsp. lactis Il1403 1114141 NP_266679.1 CDS ps221 NC_002662.1 513422 513742 D prophage ps2 protein 21 513422..513742 Lactococcus lactis subsp. lactis Il1403 1114142 NP_266680.1 CDS yfbG NC_002662.1 514066 514338 R hypothetical protein complement(514066..514338) Lactococcus lactis subsp. lactis Il1403 1114143 NP_266681.1 CDS yfbH NC_002662.1 514455 514676 D hypothetical protein 514455..514676 Lactococcus lactis subsp. lactis Il1403 1114144 NP_266682.1 CDS yfbI NC_002662.1 514845 515333 D hypothetical protein 514845..515333 Lactococcus lactis subsp. lactis Il1403 1114145 NP_266683.1 CDS yfbJ NC_002662.1 515299 515865 D hypothetical protein 515299..515865 Lactococcus lactis subsp. lactis Il1403 1114146 NP_266684.1 CDS yfbK NC_002662.1 516184 516366 D hypothetical protein 516184..516366 Lactococcus lactis subsp. lactis Il1403 1114147 NP_266685.1 CDS cspD NC_002662.1 517114 517314 D adaptations and atypical conditions; cold-shock domain family (CSD); cold shock protein D 517114..517314 Lactococcus lactis subsp. lactis Il1403 1114148 NP_266686.1 CDS yfbM NC_002662.1 517855 518352 R regulatory function; transcriptional regulator complement(517855..518352) Lactococcus lactis subsp. lactis Il1403 1114149 NP_266687.1 CDS ogt NC_002662.1 518499 519008 D DNA replication, restriction, modification, recombination, and repair; 6-O-methylguanine DNA methyltransferase 518499..519008 Lactococcus lactis subsp. lactis Il1403 1114150 NP_266688.1 CDS adaA NC_002662.1 519022 519582 D methylphosphotriester-DNA alkyltransferase 519022..519582 Lactococcus lactis subsp. lactis Il1403 1114151 NP_266689.1 CDS yfcA NC_002662.1 519676 520485 D transport and binding protein; ABC transporter ATP-binding protein 519676..520485 Lactococcus lactis subsp. lactis Il1403 1114152 NP_266690.1 CDS yfcB NC_002662.1 520482 521207 D transport and binding protein; ABC transporter permease 520482..521207 Lactococcus lactis subsp. lactis Il1403 1114153 NP_266691.1 CDS yfcC NC_002662.1 521270 521728 D hypothetical protein 521270..521728 Lactococcus lactis subsp. lactis Il1403 1114154 NP_266692.1 CDS yfcD NC_002662.1 521725 522102 D hypothetical protein 521725..522102 Lactococcus lactis subsp. lactis Il1403 1114155 NP_266693.1 CDS nifZ NC_002662.1 522216 523361 D energy metabolism, electron transport; similar to NifZ of Bacillus subtilis; cysteine sulfinate desulfinase/cysteine desulfurase, evidenced by COGnitor; pyridoxal-phosphate dependent aminotransferase 522216..523361 Lactococcus lactis subsp. lactis Il1403 1114156 NP_266694.1 CDS yfcF NC_002662.1 523468 524346 D hypothetical protein 523468..524346 Lactococcus lactis subsp. lactis Il1403 1114157 NP_266695.1 CDS yfcG NC_002662.1 524403 526052 R transport and binding protein; amino acids, peptides and amines; probably a substrate binding protein of an oligopeptide or aminoacid ABC transporter; peptide-binding protein complement(524403..526052) Lactococcus lactis subsp. lactis Il1403 1114158 NP_266696.1 CDS cysM NC_002662.1 526263 527195 R serine family; cysteine synthase complement(526263..527195) Lactococcus lactis subsp. lactis Il1403 1114159 NP_266697.1 CDS acmD NC_002662.1 527413 528498 D cell envelope, murein sacculus and peptidoglycan; muramidase needed for cell separation and responsible for autolysis; N-acetylmuramidase 527413..528498 Lactococcus lactis subsp. lactis Il1403 1114160 NP_266698.1 CDS yfcI NC_002662.1 528537 529169 R hypothetical protein complement(528537..529169) Lactococcus lactis subsp. lactis Il1403 1114161 NP_266699.1 CDS ponA NC_002662.1 529170 531164 R cell envelope, murein sacculus and peptidoglycan; penicillin-binding protein 1A complement(529170..531164) Lactococcus lactis subsp. lactis Il1403 1114162 NP_266700.1 CDS recU NC_002662.1 531232 531873 R functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC; Holliday junction-specific endonuclease complement(531232..531873) Lactococcus lactis subsp. lactis Il1403 1114163 NP_266701.1 CDS yfdB NC_002662.1 531954 532478 D hypothetical protein 531954..532478 Lactococcus lactis subsp. lactis Il1403 1114164 NP_266702.1 CDS yfdC NC_002662.1 532638 533024 D hypothetical protein 532638..533024 Lactococcus lactis subsp. lactis Il1403 1114165 NP_266703.1 CDS yfdD NC_002662.1 533116 533397 D similar to YktA protein of Bacillus subtilis; hypothetical protein 533116..533397 Lactococcus lactis subsp. lactis Il1403 1114166 NP_266704.2 CDS yfdE NC_002662.1 533381 534142 D similar to myo-inositol monophosphatases; hypothetical protein 533381..534142 Lactococcus lactis subsp. lactis Il1403 1114167 NP_266705.1 CDS murA2 NC_002662.1 534233 535516 D adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 534233..535516 Lactococcus lactis subsp. lactis Il1403 1114168 NP_266706.1 CDS yfdG NC_002662.1 535516 535710 D hypothetical protein 535516..535710 Lactococcus lactis subsp. lactis Il1403 1114169 NP_266707.1 CDS tig NC_002662.1 535867 537150 D Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 535867..537150 Lactococcus lactis subsp. lactis Il1403 1114170 NP_266708.1 CDS dnaG NC_002662.1 544010 545923 D synthesizes RNA primers at the replication forks; DNA primase 544010..545923 Lactococcus lactis subsp. lactis Il1403 1114171 NP_266709.1 CDS rpoD NC_002662.1 546000 547343 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium; RNA polymerase sigma factor RpoD 546000..547343 Lactococcus lactis subsp. lactis Il1403 1114172 NP_266710.1 CDS yfeA NC_002662.1 547458 548201 D RpiR family of transcription regulators; transcriptional regulator 547458..548201 Lactococcus lactis subsp. lactis Il1403 1114173 NP_266711.1 CDS glpT NC_002662.1 548432 549733 D transport and binding protein, carbohydrates, organic alcohols and acids; similar to Lactococcus lactishexose phosphate transport in Accession Number X71493; glycerol-3-phosphatase transporter 548432..549733 Lactococcus lactis subsp. lactis Il1403 1114174 NP_266712.1 CDS yffA NC_002662.1 550016 550354 D hypothetical protein 550016..550354 Lactococcus lactis subsp. lactis Il1403 1114175 NP_266713.1 CDS clpE NC_002662.1 550405 552651 D evidence experimental PMID:10094684; adaptations and atypical conditions; CLPC subfamily; ATP-dependent protease ATP-binding subunit 550405..552651 Lactococcus lactis subsp. lactis Il1403 1114176 NP_266714.1 CDS yffB NC_002662.1 553073 553543 R hypothetical protein complement(553073..553543) Lactococcus lactis subsp. lactis Il1403 1114177 NP_266715.1 CDS gapA NC_002662.1 553716 554729 D evidence experimental PMID:7773380; glycolysis; glyceraldehyde 3-phosphate dehydrogenase 553716..554729 Lactococcus lactis subsp. lactis Il1403 1114178 NP_266716.1 CDS def NC_002662.1 554872 555507 R cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase complement(554872..555507) Lactococcus lactis subsp. lactis Il1403 1114179 NP_266717.1 CDS yffD NC_002662.1 555661 556116 D hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 555661..556116 Lactococcus lactis subsp. lactis Il1403 1114180 NP_266718.1 CDS uvrB NC_002662.1 556127 558205 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 556127..558205 Lactococcus lactis subsp. lactis Il1403 1114181 NP_266719.1 CDS gltS NC_002662.1 558401 559210 D transport and binding protein; amino acids, peptides and amines; glutamate or arginine ABC transporter substrate binding protein 558401..559210 Lactococcus lactis subsp. lactis Il1403 1114182 NP_266720.1 CDS argE NC_002662.1 559225 560343 D glutamate family; fifth step in arginine biosynthesis; acetylornithine deacetylase 559225..560343 Lactococcus lactis subsp. lactis Il1403 1114183 NP_266721.1 CDS fabZ1 NC_002662.1 560411 560866 R fatty acid and phospholipid metabolism; (3R)-hydroxymyristoyl-ACP dehydratase complement(560411..560866) Lactococcus lactis subsp. lactis Il1403 1114184 NP_266722.1 CDS fabI NC_002662.1 561142 561894 D Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-ACP reductase 561142..561894 Lactococcus lactis subsp. lactis Il1403 1114185 NP_266723.1 CDS yfgC NC_002662.1 562156 562563 D hypothetical protein 562156..562563 Lactococcus lactis subsp. lactis Il1403 1114186 NP_266724.1 CDS yfgF NC_002662.1 563253 564173 D transport and binding protein; ABC transporter permease 563253..564173 Lactococcus lactis subsp. lactis Il1403 1114188 NP_266725.1 CDS yfgG NC_002662.1 564298 565221 R involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site; OxaA-like protein precursor complement(564298..565221) Lactococcus lactis subsp. lactis Il1403 1114189 NP_266726.1 CDS yfgH NC_002662.1 565435 566193 R hypothetical protein complement(565435..566193) Lactococcus lactis subsp. lactis Il1403 1114190 NP_266727.1 CDS yfgL NC_002662.1 566288 566878 R similar to several membrane proteins; hypothetical protein complement(566288..566878) Lactococcus lactis subsp. lactis Il1403 1114191 NP_266728.1 CDS dfpA NC_002662.1 566895 567431 R decarboxylates 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine.; phosphopantothenoylcysteine decarboxylase complement(566895..567431) Lactococcus lactis subsp. lactis Il1403 1114192 NP_266729.1 CDS dfpB NC_002662.1 567424 568119 R biosynthesis of cofactors; prosthetic groups, and carriers; apparently the middle part of the protein; probably involved in pantothenate metabolism; phosphopantothenate--cysteine ligase complement(567424..568119) Lactococcus lactis subsp. lactis Il1403 1114193 NP_266730.1 CDS xylH NC_002662.1 568265 568450 R central intermediary metabolism; 4-oxalocrotonate tautomerase complement(568265..568450) Lactococcus lactis subsp. lactis Il1403 1114194 NP_266731.1 CDS yfgQ NC_002662.1 568648 570975 D transort and binding protein, cations; cation-transporting ATPase 568648..570975 Lactococcus lactis subsp. lactis Il1403 1114195 NP_266732.1 CDS yfhA NC_002662.1 570988 571431 D paralogous to yafE; hypothetical protein 570988..571431 Lactococcus lactis subsp. lactis Il1403 1114196 NP_266733.1 CDS yfhB NC_002662.1 571538 572470 D hypothetical protein 571538..572470 Lactococcus lactis subsp. lactis Il1403 1114197 NP_266734.1 CDS yfhC NC_002662.1 572714 573307 D hypothetical protein 572714..573307 Lactococcus lactis subsp. lactis Il1403 1114198 NP_266735.1 CDS crtK NC_002662.1 573505 573987 D carotenoid biosynthetic protein CrtK 573505..573987 Lactococcus lactis subsp. lactis Il1403 1114199 NP_266736.1 CDS yfhF NC_002662.1 574106 574507 D hypothetical protein 574106..574507 Lactococcus lactis subsp. lactis Il1403 1114200 NP_266737.1 CDS yfhG NC_002662.1 574511 576307 D hypothetical protein 574511..576307 Lactococcus lactis subsp. lactis Il1403 1114201 NP_266738.1 CDS yfhH NC_002662.1 576304 577077 D hypothetical protein 576304..577077 Lactococcus lactis subsp. lactis Il1403 1114202 NP_266739.1 CDS yfhI NC_002662.1 577224 577586 D hypothetical protein 577224..577586 Lactococcus lactis subsp. lactis Il1403 1114203 NP_266740.1 CDS yfhJ NC_002662.1 577706 578074 D hypothetical protein 577706..578074 Lactococcus lactis subsp. lactis Il1403 1114204 NP_266741.1 CDS yfhK NC_002662.1 578303 578587 D hypothetical protein 578303..578587 Lactococcus lactis subsp. lactis Il1403 1114205 NP_266742.1 CDS yfhL NC_002662.1 578890 579588 R hypothetical protein complement(578890..579588) Lactococcus lactis subsp. lactis Il1403 1114206 NP_266743.1 CDS yfiA NC_002662.1 579746 580126 R hypothetical protein complement(579746..580126) Lactococcus lactis subsp. lactis Il1403 1114207 NP_266744.1 CDS umuC NC_002662.1 580086 581552 R DNA replication, restriction, modification, recombination, and repair; evidence experimental PMID:9097419; involved in UV protection and mutagenesis; may modify DNA replication machinery to allow bypass through a damaged template; UmuC complement(580086..581552) Lactococcus lactis subsp. lactis Il1403 1114208 NP_266745.1 CDS yfiC NC_002662.1 582008 582541 R hypothetical protein complement(582008..582541) Lactococcus lactis subsp. lactis Il1403 1114209 NP_266746.1 CDS yfiD NC_002662.1 582842 583351 D hypothetical protein 582842..583351 Lactococcus lactis subsp. lactis Il1403 1114210 NP_266747.1 CDS rmaJ NC_002662.1 583404 583835 R MarR-family regulators; transcriptional regulator complement(583404..583835) Lactococcus lactis subsp. lactis Il1403 1114211 NP_266748.1 CDS yfiE NC_002662.1 583936 584349 D hypothetical protein 583936..584349 Lactococcus lactis subsp. lactis Il1403 1114212 NP_266749.1 CDS yfiG NC_002662.1 584876 585445 D catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 584876..585445 Lactococcus lactis subsp. lactis Il1403 1114213 NP_266750.1 CDS yfiH NC_002662.1 585501 585944 D hypothetical protein 585501..585944 Lactococcus lactis subsp. lactis Il1403 1114214 NP_266751.1 CDS prfA NC_002662.1 585962 587035 D recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 585962..587035 Lactococcus lactis subsp. lactis Il1403 1114215 NP_266752.1 CDS yfiI NC_002662.1 587035 587562 D hypothetical protein 587035..587562 Lactococcus lactis subsp. lactis Il1403 1114216 NP_266753.1 CDS yfiJ NC_002662.1 587730 588380 D electron transport; NADPH-flavin oxidoreductase 587730..588380 Lactococcus lactis subsp. lactis Il1403 1114217 NP_266754.1 CDS hemK NC_002662.1 588486 589298 D heme and porphyrin; may be involved in the oxidation of protoporphyrinogen into protoporphyrin IX; protoporphyrinogen oxidase 588486..589298 Lactococcus lactis subsp. lactis Il1403 1114218 NP_266755.1 CDS yfiL NC_002662.1 589332 589796 D probably an acetyltransferase; hypothetical protein 589332..589796 Lactococcus lactis subsp. lactis Il1403 1114219 NP_266756.1 CDS yfjA NC_002662.1 589901 590713 D hypothetical protein 589901..590713 Lactococcus lactis subsp. lactis Il1403 1114220 NP_266757.1 CDS glyA NC_002662.1 590943 592190 D catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 590943..592190 Lactococcus lactis subsp. lactis Il1403 1114221 NP_266758.1 CDS yfjB NC_002662.1 592351 592953 D transposon related function; similar to Orf14 of Enterococcus faecalis transposon Tn916; transposon-related protein 592351..592953 Lactococcus lactis subsp. lactis Il1403 1114222 NP_266759.1 CDS serC NC_002662.1 593080 594177 D catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 593080..594177 Lactococcus lactis subsp. lactis Il1403 1114223 NP_266760.1 CDS serA NC_002662.1 594174 595370 D serine family; similar to N-terminal part of SerA; D-3-phosphoglycerate dehydrogenase 594174..595370 Lactococcus lactis subsp. lactis Il1403 1114224 NP_266761.1 CDS serB NC_002662.1 595394 596044 D serine family; phosphoserine phosphatase 595394..596044 Lactococcus lactis subsp. lactis Il1403 1114225 NP_266762.1 CDS yfjC NC_002662.1 596163 596456 R catalyzes the hydrolysis of acylphosphate; acylphosphatase complement(596163..596456) Lactococcus lactis subsp. lactis Il1403 1114226 NP_266763.1 CDS yfjD NC_002662.1 596779 597537 D RNA synthesis, modification, and DNA transcription; tRNA/rRNA methyltransferase 596779..597537 Lactococcus lactis subsp. lactis Il1403 1114227 NP_266764.2 CDS yfjE NC_002662.1 597682 598125 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin complement(597682..598125) Lactococcus lactis subsp. lactis Il1403 1114228 NP_266765.1 CDS yfjF NC_002662.1 598274 599779 R transport and binding protein; multidrug resistance; similar to many multidrug resistance transporters; membrane-bound transport protein complement(598274..599779) Lactococcus lactis subsp. lactis Il1403 1114229 NP_266768.1 CDS pepM NC_002662.1 600904 601758 D catalyzes the removal of N-terminal amino acids from peptides and arylamides; methionine aminopeptidase 600904..601758 Lactococcus lactis subsp. lactis Il1403 1114232 NP_266769.1 CDS ygaB NC_002662.1 601790 602683 D probably tRNA-processing ribonuclease; similar to ribonuclease BN; evidenced by COGnitor; hypothetical protein 601790..602683 Lactococcus lactis subsp. lactis Il1403 1114233 NP_266770.1 CDS ygaC NC_002662.1 602814 603260 R hypothetical protein complement(602814..603260) Lactococcus lactis subsp. lactis Il1403 1114234 NP_266771.1 CDS ygaD NC_002662.1 603398 604129 D hypothetical protein 603398..604129 Lactococcus lactis subsp. lactis Il1403 1114235 NP_266772.1 CDS ygaE NC_002662.1 604161 604436 D hypothetical protein 604161..604436 Lactococcus lactis subsp. lactis Il1403 1114236 NP_266773.1 CDS ygaF NC_002662.1 604542 604718 D hypothetical protein 604542..604718 Lactococcus lactis subsp. lactis Il1403 1114237 NP_266774.1 CDS ptsK NC_002662.1 604822 605751 D catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase 604822..605751 Lactococcus lactis subsp. lactis Il1403 1114238 NP_266775.1 CDS lgt NC_002662.1 605815 606600 D transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 605815..606600 Lactococcus lactis subsp. lactis Il1403 1114239 NP_266776.1 CDS ygaI NC_002662.1 606768 607187 D similar to a tropomyosin-related protein STRP from Saccharomyces cerevisiae; hypothetical protein 606768..607187 Lactococcus lactis subsp. lactis Il1403 1114240 NP_266777.1 CDS ygaJ NC_002662.1 607217 607780 D hypothetical protein 607217..607780 Lactococcus lactis subsp. lactis Il1403 1114241 NP_266778.1 CDS gnd NC_002662.1 607913 609331 D catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 607913..609331 Lactococcus lactis subsp. lactis Il1403 1114242 NP_266779.1 CDS kupA NC_002662.1 609512 611524 D transort and binding protein, cations; potassium uptake protein 609512..611524 Lactococcus lactis subsp. lactis Il1403 1114243 NP_266780.1 CDS kupB NC_002662.1 611749 613764 D transort and binding protein, cations; potassium uptake protein 611749..613764 Lactococcus lactis subsp. lactis Il1403 1114244 NP_266781.1 CDS ygbB NC_002662.1 614196 614861 D similar to YqfU of Bacillus subtilis; hypothetical protein 614196..614861 Lactococcus lactis subsp. lactis Il1403 1114245 NP_266782.1 CDS miaA NC_002662.1 614999 615883 D IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 614999..615883 Lactococcus lactis subsp. lactis Il1403 1114246 NP_266783.1 CDS ygbD NC_002662.1 615966 616634 D hypothetical protein 615966..616634 Lactococcus lactis subsp. lactis Il1403 1114247 NP_266784.1 CDS ygbE NC_002662.1 616805 617701 D probably membrane protease subunit; evidenced by COGnitor; hypothetical protein 616805..617701 Lactococcus lactis subsp. lactis Il1403 1114248 NP_266785.1 CDS ygbF NC_002662.1 618076 618336 D hypothetical protein 618076..618336 Lactococcus lactis subsp. lactis Il1403 1114249 NP_266786.1 CDS ygbG NC_002662.1 618694 619617 D member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 618694..619617 Lactococcus lactis subsp. lactis Il1403 1114250 NP_266787.1 CDS ygcA NC_002662.1 619610 620311 D aerobic energy metabolism; oxidoreductase 619610..620311 Lactococcus lactis subsp. lactis Il1403 1114251 NP_266788.1 CDS recJ NC_002662.1 620478 622706 D ssDNA-specific exonuclease RecJ 620478..622706 Lactococcus lactis subsp. lactis Il1403 1114252 NP_266789.1 CDS apt NC_002662.1 622784 623341 D catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 622784..623341 Lactococcus lactis subsp. lactis Il1403 1114253 NP_266790.1 CDS rpoE NC_002662.1 623557 624120 D participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; DNA-directed RNA polymerase subunit delta 623557..624120 Lactococcus lactis subsp. lactis Il1403 1114254 NP_266791.1 CDS ygcC NC_002662.1 624257 625909 D similar to YrrL of Bacillus subtilis; hypothetical protein 624257..625909 Lactococcus lactis subsp. lactis Il1403 1114255 NP_266792.1 CDS greA NC_002662.1 625972 626442 D necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 625972..626442 Lactococcus lactis subsp. lactis Il1403 1114256 NP_266793.1 CDS tra904E NC_002662.1 626561 627322 R evidence experimental PMID:1328163; transposon related function. IS3/IS150/IS904 family transposase; transposase of IS904E complement(626561..627322) Lactococcus lactis subsp. lactis Il1403 1114257 NP_266794.1 CDS ygcD NC_002662.1 627418 627708 R transposon related function; hypothetical protein complement(627418..627708) Lactococcus lactis subsp. lactis Il1403 1114258 NP_266795.1 CDS tra1077D NC_002662.1 627782 628465 R evidence experimental PMID:1328163; transposon related function. IS3/IS150/IS904 family transposase; IS1077D transposase complement(627782..628465) Lactococcus lactis subsp. lactis Il1403 1114259 NP_266796.1 CDS ygcE NC_002662.1 628597 629154 R transposon related function; hypothetical protein complement(628597..629154) Lactococcus lactis subsp. lactis Il1403 1114260 NP_266797.1 CDS ctsR NC_002662.1 629354 629809 D transctiptional regulator; adaptations and atypical conditions; regulator of class III stress genes (clpC, clpP); hypothetical protein 629354..629809 Lactococcus lactis subsp. lactis Il1403 1114261 NP_266798.1 CDS clpC NC_002662.1 629799 632249 D evidence experimental PMID:10094684; adaptations and atypical conditions; CLPC subfamily; ATP-dependent protease ATP-binding subunit 629799..632249 Lactococcus lactis subsp. lactis Il1403 1114262 NP_266799.1 CDS ygdA NC_002662.1 632384 632941 D hypothetical protein 632384..632941 Lactococcus lactis subsp. lactis Il1403 1114263 NP_266800.1 CDS eno NC_002662.1 633126 634427 D enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 633126..634427 Lactococcus lactis subsp. lactis Il1403 1114264 NP_266801.1 CDS xerD NC_002662.1 634512 635450 D DNA replication, restriction, modification, recombination, and repair; integrase-recombinase 634512..635450 Lactococcus lactis subsp. lactis Il1403 1114265 NP_266802.1 CDS ygdC NC_002662.1 635723 636490 D hypothetical protein 635723..636490 Lactococcus lactis subsp. lactis Il1403 1114266 NP_266803.1 CDS ygdD NC_002662.1 637078 637218 D hypothetical protein 637078..637218 Lactococcus lactis subsp. lactis Il1403 1114267 NP_266804.1 CDS ygdF NC_002662.1 637534 637716 D hypothetical protein 637534..637716 Lactococcus lactis subsp. lactis Il1403 1114268 NP_266805.1 CDS ygdE NC_002662.1 637738 638907 D hypothetical protein 637738..638907 Lactococcus lactis subsp. lactis Il1403 1114269 NP_266806.1 CDS hsdR NC_002662.1 640780 643767 D type I restriction enzyme R protein 640780..643767 Lactococcus lactis subsp. lactis Il1403 1114271 NP_266807.1 CDS hsdM NC_002662.1 643807 645354 D type I restriction enzyme M protein 643807..645354 Lactococcus lactis subsp. lactis Il1403 1114272 NP_266808.1 CDS hsdS NC_002662.1 645351 646574 D DNA replication, restriction, modification, recombination, and repair; evidence experimental PMID:9593305; subunit S dictates DNA sequence specificity; type I restriction enzyme specificity protein 645351..646574 Lactococcus lactis subsp. lactis Il1403 1114273 NP_835298.1 CDS L200023 NC_002662.1 646595 646720 D hypothetical protein 646595..646720 Lactococcus lactis subsp. lactis Il1403 1114274 NP_266809.1 CDS ygeA NC_002662.1 646698 647777 D hypothetical protein 646698..647777 Lactococcus lactis subsp. lactis Il1403 1114275 NP_266810.1 CDS ygeB NC_002662.1 647939 648208 D hypothetical protein 647939..648208 Lactococcus lactis subsp. lactis Il1403 1114276 NP_266811.1 CDS ygeC NC_002662.1 648543 648710 D hypothetical protein 648543..648710 Lactococcus lactis subsp. lactis Il1403 1114277 NP_266812.1 CDS ygeD NC_002662.1 648976 649746 D hypothetical protein 648976..649746 Lactococcus lactis subsp. lactis Il1403 1114278 NP_266813.1 CDS tra981C NC_002662.1 650157 650996 R evidence experimental PMID:8389385; transposon related function. related to a family of IS elements that includes IS2, IS3, IS150, IS600, IS629, IS861, IS904 and ISL1; transposase of IS981C complement(650157..650996) Lactococcus lactis subsp. lactis Il1403 1114279 NP_266814.1 CDS ygfF NC_002662.1 651008 651175 R transposon related function; orf1 of IS981; transposase complement(651008..651175) Lactococcus lactis subsp. lactis Il1403 1114280 NP_835299.1 CDS L200024 NC_002662.1 651422 651511 D hypothetical protein 651422..651511 Lactococcus lactis subsp. lactis Il1403 1114281 NP_835300.1 CDS L200025 NC_002662.1 651800 651895 D hypothetical protein 651800..651895 Lactococcus lactis subsp. lactis Il1403 1114282 NP_266815.1 CDS ygfA NC_002662.1 652010 652681 R transport and binding protein; ABC transporter ATP-binding protein complement(652010..652681) Lactococcus lactis subsp. lactis Il1403 1114283 NP_266816.1 CDS ygfB NC_002662.1 652684 653757 R transport and binding protein; ABC transporter permease complement(652684..653757) Lactococcus lactis subsp. lactis Il1403 1114284 NP_266817.1 CDS ygfC NC_002662.1 653769 654338 R TetR/AcrR family of transcription regulators; transcriptional regulator complement(653769..654338) Lactococcus lactis subsp. lactis Il1403 1114285 NP_266818.1 CDS fadD NC_002662.1 654526 656049 R fatty acid and phospholipid metabolism; long-chain acyl-CoA synthetase complement(654526..656049) Lactococcus lactis subsp. lactis Il1403 1114286 NP_266819.1 CDS ygfE NC_002662.1 656294 657157 D transort and binding protein; cations; divalent cation transport-related protein 656294..657157 Lactococcus lactis subsp. lactis Il1403 1114287 NP_266820.1 CDS pfl NC_002662.1 657418 659781 D evidence experimental PMID:9294449; energy metabolism; fermentation; pyruvate-formate lyase 657418..659781 Lactococcus lactis subsp. lactis Il1403 1114288 NP_266821.1 CDS coaE NC_002662.1 659913 660572 D catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 659913..660572 Lactococcus lactis subsp. lactis Il1403 1114289 NP_266822.1 CDS pmrA NC_002662.1 660575 661792 D transport and binding protein; multidrug resistance; similar to PmrA of Streptococcus pneumoniae; multidrug resistance efflux pump 660575..661792 Lactococcus lactis subsp. lactis Il1403 1114290 NP_266823.1 CDS rpmG NC_002662.1 661789 661935 D in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 661789..661935 Lactococcus lactis subsp. lactis Il1403 1114291 NP_266824.1 CDS ftsW1 NC_002662.1 662276 663538 D cell division protein; similar to cell division protein FtsW of Enterococcus hirae; FtsW1 662276..663538 Lactococcus lactis subsp. lactis Il1403 1114292 NP_266825.1 CDS pycA NC_002662.1 663644 667057 D biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate; pyruvate carboxylase 663644..667057 Lactococcus lactis subsp. lactis Il1403 1114293 NP_266826.2 CDS gltA NC_002662.1 667208 668506 D catalyzes the formation of citrate from acetyl-CoA and oxaloacetate; citrate synthase 667208..668506 Lactococcus lactis subsp. lactis Il1403 1114294 NP_266827.1 CDS citB NC_002662.1 668503 671049 D Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 668503..671049 Lactococcus lactis subsp. lactis Il1403 1114295 NP_266828.1 CDS icd NC_002662.1 671070 672308 D TCA cycle; glutamate synthesis; isocitrate dehydrogenase 671070..672308 Lactococcus lactis subsp. lactis Il1403 1114296 NP_266829.1 CDS clpP NC_002662.1 672374 672973 R hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit complement(672374..672973) Lactococcus lactis subsp. lactis Il1403 1114297 NP_266830.1 CDS yghB NC_002662.1 673194 673700 D hypothetical protein 673194..673700 Lactococcus lactis subsp. lactis Il1403 1114298 NP_266831.1 CDS spxA NC_002662.1 673860 674258 D the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; transcriptional regulator Spx 673860..674258 Lactococcus lactis subsp. lactis Il1403 1114299 NP_266832.1 CDS yghD NC_002662.1 674640 675608 R hypothetical protein complement(674640..675608) Lactococcus lactis subsp. lactis Il1403 1114300 NP_266833.1 CDS yghE NC_002662.1 675656 675853 R hypothetical protein complement(675656..675853) Lactococcus lactis subsp. lactis Il1403 1114301 NP_266834.1 CDS pacL NC_002662.1 676147 678903 D transort and binding protein, cations; cation-transporting ATPase 676147..678903 Lactococcus lactis subsp. lactis Il1403 1114302 NP_266835.1 CDS yghG NC_002662.1 679391 680422 D hypothetical protein 679391..680422 Lactococcus lactis subsp. lactis Il1403 1114303 NP_266836.1 CDS icaA NC_002662.1 680427 681491 D surface polysaccharides, lipopolysaccharides and antigens; similar to intercellular adhesion locus protein IcaA of Staphylococcus epidermidis; glycosyl transferase family protein 680427..681491 Lactococcus lactis subsp. lactis Il1403 1114304 NP_266837.1 CDS tra983A NC_002662.1 681575 682522 D transposon related function; belongs to the IS30 family of transposase; transposase of IS983A 681575..682522 Lactococcus lactis subsp. lactis Il1403 1114305 NP_266838.1 CDS icaB NC_002662.1 682537 683367 D surface polysaccharides, lipopolysaccharides and antigens; similar to intercellular adhesion locus protein IcaB of Staphylococcus epidermidis; intercellular adhesion protein 682537..683367 Lactococcus lactis subsp. lactis Il1403 1114306 NP_266839.1 CDS ygiC NC_002662.1 683394 683639 D similar to peptidoglycan bound protein; hypothetical protein 683394..683639 Lactococcus lactis subsp. lactis Il1403 1114307 NP_266840.1 CDS icaC NC_002662.1 683636 684646 D surface polysaccharides, lipopolysaccharides and antigens; mediates attachement of cells to collagen containing substrates; collagen adhesin 683636..684646 Lactococcus lactis subsp. lactis Il1403 1114308 NP_266841.1 CDS ygiG NC_002662.1 686532 686849 R probably ATPase with chaperone activity, ATP-binding domain, evidenced by COGnitor; hypothetical protein complement(686532..686849) Lactococcus lactis subsp. lactis Il1403 1114310 NP_266842.1 CDS ygiH NC_002662.1 686804 687118 R hypothetical protein complement(686804..687118) Lactococcus lactis subsp. lactis Il1403 1114311 NP_266843.1 CDS ygiI NC_002662.1 687395 688168 D hydrolase of PHP superfamily; hypothetical protein 687395..688168 Lactococcus lactis subsp. lactis Il1403 1114312 NP_266844.1 CDS ygiJ NC_002662.1 688206 688739 D similar to Listeria monocytogenes FlaR; hypothetical protein 688206..688739 Lactococcus lactis subsp. lactis Il1403 1114313 NP_266845.1 CDS ygiK NC_002662.1 688717 689337 D hypothetical protein 688717..689337 Lactococcus lactis subsp. lactis Il1403 1114314 NP_266846.1 CDS ksgA NC_002662.1 689448 690332 D catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 689448..690332 Lactococcus lactis subsp. lactis Il1403 1114315 NP_266847.1 CDS pepP NC_002662.1 690433 691491 D evidence experimental PMID:9797327; degradation of proteins, peptides, and glycopeptides; aminopeptidase P 690433..691491 Lactococcus lactis subsp. lactis Il1403 1114316 NP_266848.1 CDS efp NC_002662.1 691623 692180 D Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 691623..692180 Lactococcus lactis subsp. lactis Il1403 1114317 NP_266849.1 CDS ygjB NC_002662.1 692276 692728 D hypothetical protein 692276..692728 Lactococcus lactis subsp. lactis Il1403 1114318 NP_266850.1 CDS nusB NC_002662.1 692721 693692 D transcription termination protein; RNA synthesis, modification, and DNA transcription; hypothetical protein 692721..693692 Lactococcus lactis subsp. lactis Il1403 1114319 NP_266853.1 CDS glgC NC_002662.1 696013 697155 D catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 696013..697155 Lactococcus lactis subsp. lactis Il1403 1114322 NP_266854.1 CDS glgD NC_002662.1 697145 698284 D central intermediary metabolism; subunit of ADP-glucose pyrophosphorylase; glucose-1-phosphate adenylyltransferase 697145..698284 Lactococcus lactis subsp. lactis Il1403 1114323 NP_266855.1 CDS glgA NC_002662.1 698361 699812 D catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 698361..699812 Lactococcus lactis subsp. lactis Il1403 1114324 NP_266856.1 CDS glgP NC_002662.1 699901 702303 D central intermediary metabolism; glycogen phosphorylase 699901..702303 Lactococcus lactis subsp. lactis Il1403 1114325 NP_266857.1 CDS apu NC_002662.1 702393 704195 D degradation of polysaccharides; amylopullulanase 702393..704195 Lactococcus lactis subsp. lactis Il1403 1114326 NP_266858.1 CDS dtpT NC_002662.1 704421 705914 D evidence experimental PMID:8157671; transport and binding protein; amino acids, peptides and amines; di-/tripeptide transporter 704421..705914 Lactococcus lactis subsp. lactis Il1403 1114327 NP_266859.1 CDS tra983B NC_002662.1 706695 707642 D transposon related function; belongs to the IS30 family of transposase; transposase of IS983B 706695..707642 Lactococcus lactis subsp. lactis Il1403 1114328 NP_266860.1 CDS cydA NC_002662.1 707710 709185 D energy metabolism; electron transport; cytochrome D ubiquinol oxidase subunit I 707710..709185 Lactococcus lactis subsp. lactis Il1403 1114329 NP_266861.1 CDS cydB NC_002662.1 709185 710180 D energy metabolism; electron transport; cytochrome D ubiquinol oxidase subunit II 709185..710180 Lactococcus lactis subsp. lactis Il1403 1114330 NP_266862.2 CDS cydC NC_002662.1 710487 712376 D transport and binding protein; multidrug resistance; involved in the cytochrome D branch of aerobic respiration; MDR subfamily; cytochrome D ABC transporter ATP-binding protein/permease 710487..712376 Lactococcus lactis subsp. lactis Il1403 1114331 NP_266863.1 CDS cydD NC_002662.1 712348 714069 D transport and binding protein; multidrug resistance; involved in the cytochrome D branch of aerobic respiration; MDR subfamily; cytochrome D ABC transporter ATP-binding protein/permease 712348..714069 Lactococcus lactis subsp. lactis Il1403 1114332 NP_266864.1 CDS rmaB NC_002662.1 714363 715238 D MarR-family regulators; belongs to the MarR family; transcriptional regulator 714363..715238 Lactococcus lactis subsp. lactis Il1403 1114333 NP_266865.1 CDS yhbE NC_002662.1 715264 715752 D hypothetical protein 715264..715752 Lactococcus lactis subsp. lactis Il1403 1114334 NP_266866.1 CDS yhbF NC_002662.1 715779 716453 D similar to several proteins from eukaryotes; hypothetical protein 715779..716453 Lactococcus lactis subsp. lactis Il1403 1114335 NP_266867.1 CDS lmrA NC_002662.1 716555 718309 D evidence experimental PMID:8855237; transport and binding protein; multidrug resistance; multidrug resistance ABC transporter ATP-binding protein/permease 716555..718309 Lactococcus lactis subsp. lactis Il1403 1114336 NP_266868.1 CDS yhbH NC_002662.1 718328 718939 R hypothetical protein complement(718328..718939) Lactococcus lactis subsp. lactis Il1403 1114337 NP_266869.1 CDS apl NC_002662.1 719010 719654 R phosphorus compounds; complements a phoA mutation in Escherichia coli; alkaline phosphatase complement(719010..719654) Lactococcus lactis subsp. lactis Il1403 1114338 NP_266870.1 CDS yhcA NC_002662.1 719869 721863 R transport and binding protein; ABC transporter ATP-binding protein/permease complement(719869..721863) Lactococcus lactis subsp. lactis Il1403 1114339 NP_266871.1 CDS yhcC NC_002662.1 721971 722189 R similar to hypothetical protein MJ1230 of Methanococcus jannaschii; hypothetical protein complement(721971..722189) Lactococcus lactis subsp. lactis Il1403 1114340 NP_266872.1 CDS yhcB NC_002662.1 722399 723061 D hypothetical protein 722399..723061 Lactococcus lactis subsp. lactis Il1403 1114341 NP_266873.1 CDS qor NC_002662.1 723093 724079 R energy metabolism; electron transport; quinone oxidoreductase complement(723093..724079) Lactococcus lactis subsp. lactis Il1403 1114342 NP_266874.1 CDS yhcE NC_002662.1 724247 725356 D probably methionine synthase II, evidenced by COGnitor; hypothetical protein 724247..725356 Lactococcus lactis subsp. lactis Il1403 1114343 NP_266875.1 CDS yhcG NC_002662.1 725482 726234 D probably metal-dependent hydrolase, evidenced by COGnitor; hypothetical protein 725482..726234 Lactococcus lactis subsp. lactis Il1403 1114344 NP_266876.1 CDS yhcH NC_002662.1 726222 727160 D probably protein phosphatase, evidenced by COGnitor; hypothetical protein 726222..727160 Lactococcus lactis subsp. lactis Il1403 1114345 NP_266877.1 CDS yhcI NC_002662.1 727161 727628 D probably amino acid deaminase, evidenced by COGnitor; hypothetical protein 727161..727628 Lactococcus lactis subsp. lactis Il1403 1114346 NP_266878.1 CDS tra981D NC_002662.1 728130 728969 R evidence experimental PMID:8389385; transposon related function. related to a family of IS elements that includes IS2, IS3, IS150, IS600, IS629, IS861, IS904 and ISL1; transposase of IS981D complement(728130..728969) Lactococcus lactis subsp. lactis Il1403 1114347 NP_266879.1 CDS yhcJ NC_002662.1 728981 729241 R transposon related function; orf1 of IS981; transposase complement(728981..729241) Lactococcus lactis subsp. lactis Il1403 1114348 NP_835301.1 CDS L200027 NC_002662.1 729346 729459 D hypothetical protein 729346..729459 Lactococcus lactis subsp. lactis Il1403 1114349 NP_266880.1 CDS yhcK NC_002662.1 729487 730284 D similar to C-terminal parts of alpha-glucosidases from differenr species; hypothetical protein 729487..730284 Lactococcus lactis subsp. lactis Il1403 1114350 NP_266881.1 CDS rliC NC_002662.1 730327 731367 D LacI-family regulators; LacI family transcriptional regulator 730327..731367 Lactococcus lactis subsp. lactis Il1403 1114351 NP_266882.1 CDS yhdA NC_002662.1 731368 731784 R similar to ComAB (YuxO) protein of Bacillus subtilis; hypothetical protein complement(731368..731784) Lactococcus lactis subsp. lactis Il1403 1114352 NP_266883.1 CDS yhdB NC_002662.1 731781 732884 R menaquinone and ubiquinone; probably involved in menaquinone biosynthesis; racemase complement(731781..732884) Lactococcus lactis subsp. lactis Il1403 1114353 NP_266884.2 CDS menE NC_002662.1 732881 734236 R menaquinone and ubiquinone; O-succinylbenzoic acid--CoA ligase complement(732881..734236) Lactococcus lactis subsp. lactis Il1403 1114354 NP_266885.1 CDS menB NC_002662.1 734363 735205 R catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase complement(734363..735205) Lactococcus lactis subsp. lactis Il1403 1114355 NP_266886.1 CDS menX NC_002662.1 735592 736407 R menaquinone and ubiquinone; counterpart of Bacillus subtilis YtxM; YtxM-like protein complement(735592..736407) Lactococcus lactis subsp. lactis Il1403 1114356 NP_266887.1 CDS menD NC_002662.1 736397 738079 R menaquinone and ubiquinone; 2-oxoglutarate decarboxylase complement(736397..738079) Lactococcus lactis subsp. lactis Il1403 1114357 NP_266888.1 CDS menF NC_002662.1 738133 739347 R menaquinone and ubiquinone; menaquinone-specific isochorismate synthase complement(738133..739347) Lactococcus lactis subsp. lactis Il1403 1114358 NP_266889.1 CDS yhdC NC_002662.1 739685 740266 D ribosomal proteins: synthesis and modification; acetyl transferase 739685..740266 Lactococcus lactis subsp. lactis Il1403 1114359 NP_266890.1 CDS yheA NC_002662.1 740273 741553 D similar to YtoI of Bacillus subtilis; hypothetical protein 740273..741553 Lactococcus lactis subsp. lactis Il1403 1114360 NP_266891.1 CDS yheB NC_002662.1 741571 742494 D similar to YtqI of Bacillus subtilis; hypothetical protein 741571..742494 Lactococcus lactis subsp. lactis Il1403 1114361 NP_266892.1 CDS ansB NC_002662.1 742698 743669 R energy metabolism, amino acids and amines; L-asparaginase complement(742698..743669) Lactococcus lactis subsp. lactis Il1403 1114362 NP_266893.1 CDS yheD NC_002662.1 743861 745249 D hypothetical protein 743861..745249 Lactococcus lactis subsp. lactis Il1403 1114363 NP_266894.1 CDS yheE NC_002662.1 745339 745683 D hypothetical protein 745339..745683 Lactococcus lactis subsp. lactis Il1403 1114364 NP_266895.1 CDS floL NC_002662.1 745742 747253 D surface polysaccharides, lipopolysaccharides and antigens; similar to flotillin; flotillin-like protein 745742..747253 Lactococcus lactis subsp. lactis Il1403 1114365 NP_266896.1 CDS thrA NC_002662.1 747291 748643 R catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; aspartate kinase complement(747291..748643) Lactococcus lactis subsp. lactis Il1403 1114366 NP_266897.1 CDS yheG NC_002662.1 748873 749739 R probably phosphoesterase, evidenced by COGnitor; hypothetical protein complement(748873..749739) Lactococcus lactis subsp. lactis Il1403 1114367 NP_266898.1 CDS rmaA NC_002662.1 749729 750205 R MarR-family regulators; MarR family transcriptional regulator complement(749729..750205) Lactococcus lactis subsp. lactis Il1403 1114368 NP_266899.1 CDS yhfA NC_002662.1 750333 751001 D Similar to phosphoglucomutases and phosphoglycolate phosphatases from different species; hypothetical protein 750333..751001 Lactococcus lactis subsp. lactis Il1403 1114369 NP_266900.1 CDS yhfB NC_002662.1 751095 753059 D similar to YybT of Bacillus subtilis; hypothetical protein 751095..753059 Lactococcus lactis subsp. lactis Il1403 1114370 NP_266901.1 CDS rplI NC_002662.1 753056 753508 D in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 753056..753508 Lactococcus lactis subsp. lactis Il1403 1114371 NP_266902.1 CDS dnaC NC_002662.1 753514 754881 D DNA replication, restriction, modification, recombination, and repair; corresponds to the dnaC gene from Bacillus subtilis; replicative DNA helicase 753514..754881 Lactococcus lactis subsp. lactis Il1403 1114372 NP_266903.1 CDS yhfC NC_002662.1 755076 755333 D hypothetical protein 755076..755333 Lactococcus lactis subsp. lactis Il1403 1114373 NP_266904.1 CDS yhfD NC_002662.1 755402 756175 D similar to YtmP of Bacillus subtilis; hypothetical protein 755402..756175 Lactococcus lactis subsp. lactis Il1403 1114374 NP_266905.1 CDS trmB NC_002662.1 756296 756949 D tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 756296..756949 Lactococcus lactis subsp. lactis Il1403 1114375 NP_266906.1 CDS nrdR NC_002662.1 757068 757514 D transcriptional regulator NrdR 757068..757514 Lactococcus lactis subsp. lactis Il1403 1114376 NP_835302.1 CDS L200028 NC_002662.1 757501 757836 R hypothetical protein complement(757501..757836) Lactococcus lactis subsp. lactis Il1403 1114377 NP_266907.1 CDS dnaB NC_002662.1 757902 759077 D DNA replication, restriction, modification, recombination, and repair; replication protein; counterpart to the Bacillus subtilis DnaB protein, based on sequence similarity and chromosomal position; hypothetical protein 757902..759077 Lactococcus lactis subsp. lactis Il1403 1114378 NP_266908.1 CDS dnaI NC_002662.1 759077 759958 D Primosomal protein that may act to load helicase DnaC during DNA replication; primosomal protein DnaI 759077..759958 Lactococcus lactis subsp. lactis Il1403 1114379 NP_266909.1 CDS yhgA NC_002662.1 759951 760679 D aerobic energy metabolism; oxidoreductase 759951..760679 Lactococcus lactis subsp. lactis Il1403 1114380 NP_266910.1 CDS yhgB NC_002662.1 760781 761296 D similar to YisX of Bacillus subtilis; hypothetical protein 760781..761296 Lactococcus lactis subsp. lactis Il1403 1114381 NP_266911.1 CDS engA NC_002662.1 761403 762713 D EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 761403..762713 Lactococcus lactis subsp. lactis Il1403 1114382 NP_266912.1 CDS yhgC NC_002662.1 762819 763631 D similar to positive regulator GadR of Lactococcus lactis; transcriptional regulator 762819..763631 Lactococcus lactis subsp. lactis Il1403 1114383 NP_266913.1 CDS yhgD NC_002662.1 764114 767656 D hypothetical protein 764114..767656 Lactococcus lactis subsp. lactis Il1403 1114384 NP_266914.1 CDS yhgE NC_002662.1 767788 769632 D hypothetical protein 767788..769632 Lactococcus lactis subsp. lactis Il1403 1114385 NP_266915.1 CDS yhhA NC_002662.1 769694 770992 D similar to fimbria-associated protein from Actinomyces naeslundii; integral membrane protein; hypothetical protein 769694..770992 Lactococcus lactis subsp. lactis Il1403 1114386 NP_266916.1 CDS yhhB NC_002662.1 770979 771704 D hypothetical protein 770979..771704 Lactococcus lactis subsp. lactis Il1403 1114387 NP_266917.1 CDS yhhC NC_002662.1 771778 772476 R integral membrane protein; hypothetical protein complement(771778..772476) Lactococcus lactis subsp. lactis Il1403 1114388 NP_266918.1 CDS yhhD NC_002662.1 772495 772899 R similar to PH1801 of Pyrococcus horikoshii.; hypothetical protein complement(772495..772899) Lactococcus lactis subsp. lactis Il1403 1114389 NP_266919.1 CDS yhhE NC_002662.1 773172 773645 D in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 773172..773645 Lactococcus lactis subsp. lactis Il1403 1114390 NP_266920.1 CDS nusA NC_002662.1 773810 774958 D modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 773810..774958 Lactococcus lactis subsp. lactis Il1403 1114391 NP_266921.1 CDS yhhG NC_002662.1 775124 775450 D hypothetical protein 775124..775450 Lactococcus lactis subsp. lactis Il1403 1114392 NP_266922.1 CDS ylxQ NC_002662.1 775453 775758 D ribosomal proteins; synthesis and modification; similar to YlxQ of Bacillus subtilis, supposed to be a ribosomal protein. Located close to the genes implicated in protein biosynthesis.; hypothetical protein 775453..775758 Lactococcus lactis subsp. lactis Il1403 1114393 NP_266923.1 CDS infB NC_002662.1 775779 778613 D Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 775779..778613 Lactococcus lactis subsp. lactis Il1403 1114394 NP_266924.1 CDS rbfA NC_002662.1 778883 779242 D associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 778883..779242 Lactococcus lactis subsp. lactis Il1403 1114395 NP_266925.1 CDS pmi NC_002662.1 779421 780368 D mannose-6-phosphate isomerase 779421..780368 Lactococcus lactis subsp. lactis Il1403 1114396 NP_266926.1 CDS rmaG NC_002662.1 780787 781227 D MarR-family regulator; MarR family transcriptional regulator 780787..781227 Lactococcus lactis subsp. lactis Il1403 1114397 NP_266927.1 CDS fabH NC_002662.1 781227 782204 D FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 781227..782204 Lactococcus lactis subsp. lactis Il1403 1114398 NP_266928.1 CDS acpP NC_002662.1 782371 782592 D carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 782371..782592 Lactococcus lactis subsp. lactis Il1403 1114399 NP_266929.1 CDS fabD NC_002662.1 782872 783798 D fatty acid and phospholipid metabolism; ACP S-malonyltransferase 782872..783798 Lactococcus lactis subsp. lactis Il1403 1114400 NP_266930.1 CDS fabG NC_002662.1 783884 784615 D catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 783884..784615 Lactococcus lactis subsp. lactis Il1403 1114401 NP_266931.1 CDS fabF NC_002662.1 784656 785885 D fatty acid and phospholipid metabolism; 3-oxoacyl-ACP synthase 784656..785885 Lactococcus lactis subsp. lactis Il1403 1114402 NP_266932.1 CDS accB NC_002662.1 785892 786359 D composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 785892..786359 Lactococcus lactis subsp. lactis Il1403 1114403 NP_266933.1 CDS fabZ NC_002662.1 786486 786920 D in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 786486..786920 Lactococcus lactis subsp. lactis Il1403 1114404 NP_266934.1 CDS accC NC_002662.1 787314 788681 D an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 787314..788681 Lactococcus lactis subsp. lactis Il1403 1114405 NP_266935.1 CDS accD NC_002662.1 788767 789633 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 788767..789633 Lactococcus lactis subsp. lactis Il1403 1114406 NP_266936.1 CDS accA NC_002662.1 789626 790408 D fatty acid and phospholipid metabolism; acetyl-CoA carboxylase carboxyl transferase subunit alpha 789626..790408 Lactococcus lactis subsp. lactis Il1403 1114407 NP_266937.1 CDS metB2 NC_002662.1 790537 791679 D catalyzes the formation of L-cystathionine from O-succinyl-L-homoserine and L-cysteine; or Cystathionine beta-lyase (CBL) can convert cystathionine to homocysteine; cystathionine gamma-synthase 790537..791679 Lactococcus lactis subsp. lactis Il1403 1114408 NP_266938.1 CDS cysK NC_002662.1 791894 792814 D serine family; there is another potential cysteine synthase cysM in the genome; cysteine synthase 791894..792814 Lactococcus lactis subsp. lactis Il1403 1114409 NP_266939.1 CDS yhjA NC_002662.1 793043 793282 D hypothetical protein 793043..793282 Lactococcus lactis subsp. lactis Il1403 1114410 NP_266940.1 CDS yhjB NC_002662.1 793339 793716 D hypothetical protein 793339..793716 Lactococcus lactis subsp. lactis Il1403 1114411 NP_266941.1 CDS yhjC NC_002662.1 793727 794035 D hypothetical protein 793727..794035 Lactococcus lactis subsp. lactis Il1403 1114412 NP_266942.1 CDS noxC NC_002662.1 794032 795675 D aerobic energy metabolism; NADH oxidase 794032..795675 Lactococcus lactis subsp. lactis Il1403 1114413 NP_266943.1 CDS yhjE NC_002662.1 795702 795956 D similar to YrkD of Bacillus subtilis; hypothetical protein 795702..795956 Lactococcus lactis subsp. lactis Il1403 1114414 NP_266944.1 CDS yhjF NC_002662.1 796032 796382 D hypothetical protein 796032..796382 Lactococcus lactis subsp. lactis Il1403 1114415 NP_266945.1 CDS rdrA NC_002662.1 796549 797292 R DeoR-family regulators; transcriptional regulator complement(796549..797292) Lactococcus lactis subsp. lactis Il1403 1114416 NP_266946.1 CDS yhjG NC_002662.1 797386 797949 R ribosomal proteins: synthesis and modification; acetyl transferase complement(797386..797949) Lactococcus lactis subsp. lactis Il1403 1114417 NP_266947.1 CDS exoA NC_002662.1 798032 799036 R degradation of DNA; AP/EXOA family of DNA repair enzymes; exodeoxyribonuclease A complement(798032..799036) Lactococcus lactis subsp. lactis Il1403 1114418 NP_266948.1 CDS metS NC_002662.1 799071 801059 D amino acyl tRNA synthetases; methyonyl-tRNA synthetase 799071..801059 Lactococcus lactis subsp. lactis Il1403 1114419 NP_266949.1 CDS yiaA NC_002662.1 801265 801504 D hypothetical protein 801265..801504 Lactococcus lactis subsp. lactis Il1403 1114420 NP_266950.1 CDS fabG NC_002662.1 801521 802252 D Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 801521..802252 Lactococcus lactis subsp. lactis Il1403 1114421 NP_266951.1 CDS yiaC NC_002662.1 802593 803165 D hypothetical protein 802593..803165 Lactococcus lactis subsp. lactis Il1403 1114422 NP_266952.1 CDS yiaD NC_002662.1 803269 803901 D similar to YwnB protein of Bacillus subtilis; probably nucleoside-diphosphate-sugar epimerase, evidenced by COGnitor; NADH-flavin reductase 803269..803901 Lactococcus lactis subsp. lactis Il1403 1114423 NP_266953.1 CDS argC NC_002662.1 804041 805063 D catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 804041..805063 Lactococcus lactis subsp. lactis Il1403 1114424 NP_266954.1 CDS argJ NC_002662.1 805075 806265 D bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase 805075..806265 Lactococcus lactis subsp. lactis Il1403 1114425 NP_266955.1 CDS argD NC_002662.1 806278 807411 D glutamate family; acetylornithine aminotransferase 806278..807411 Lactococcus lactis subsp. lactis Il1403 1114426 NP_266956.1 CDS argB NC_002662.1 807408 808259 D catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 807408..808259 Lactococcus lactis subsp. lactis Il1403 1114427 NP_266957.1 CDS argF NC_002662.1 808287 809288 D catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase 808287..809288 Lactococcus lactis subsp. lactis Il1403 1114428 NP_266958.1 CDS rnc NC_002662.1 809461 810156 D cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 809461..810156 Lactococcus lactis subsp. lactis Il1403 1114429 NP_266961.1 CDS yibC NC_002662.1 813912 816080 D hypothetical protein 813912..816080 Lactococcus lactis subsp. lactis Il1403 1114432 NP_266962.1 CDS yibD NC_002662.1 816171 816581 D hypothetical protein 816171..816581 Lactococcus lactis subsp. lactis Il1403 1114433 NP_266963.1 CDS yibE NC_002662.1 816609 817790 D hypothetical protein 816609..817790 Lactococcus lactis subsp. lactis Il1403 1114434 NP_266964.1 CDS yibF NC_002662.1 817787 818548 D hypothetical protein 817787..818548 Lactococcus lactis subsp. lactis Il1403 1114435 NP_266965.1 CDS yibG NC_002662.1 818598 819938 R transport and binding protein; amino acids, peptides and amines; similar to many amino acid permeases; amino acid permease complement(818598..819938) Lactococcus lactis subsp. lactis Il1403 1114436 NP_266966.1 CDS yicA NC_002662.1 820452 822542 D hypothetical protein 820452..822542 Lactococcus lactis subsp. lactis Il1403 1114437 NP_266967.1 CDS yicB NC_002662.1 822669 823478 D hypothetical protein 822669..823478 Lactococcus lactis subsp. lactis Il1403 1114438 NP_266968.1 CDS yicC NC_002662.1 823488 824039 D integral membrane protein; hypothetical protein 823488..824039 Lactococcus lactis subsp. lactis Il1403 1114439 NP_266969.1 CDS ftsY NC_002662.1 824101 825480 D cell division protein; hypothetical protein 824101..825480 Lactococcus lactis subsp. lactis Il1403 1114440 NP_266970.1 CDS prsA NC_002662.1 825656 826630 D catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 825656..826630 Lactococcus lactis subsp. lactis Il1403 1114441 NP_266971.1 CDS yicE NC_002662.1 826703 827374 D hypothetical protein 826703..827374 Lactococcus lactis subsp. lactis Il1403 1114442 NP_266972.1 CDS leuS NC_002662.1 827445 829934 D leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 827445..829934 Lactococcus lactis subsp. lactis Il1403 1114443 NP_266973.1 CDS yidA NC_002662.1 830200 830955 D RpiR family of transcription regulators; transcriptional regulator 830200..830955 Lactococcus lactis subsp. lactis Il1403 1114444 NP_266974.1 CDS yidB NC_002662.1 831369 832787 D transport and binding protein; PTS system; PTS system cellobiose-specific transporter subunit IIC 831369..832787 Lactococcus lactis subsp. lactis Il1403 1114445 NP_266975.1 CDS yidC NC_002662.1 832872 834233 D energy metabolism, Sugars; beta-glucosidase family; beta-glucosidase 832872..834233 Lactococcus lactis subsp. lactis Il1403 1114446 NP_266976.1 CDS cpo NC_002662.1 834485 835288 D adaptations and atypical conditions; belongs to chloro/bromoperoxidase family.; non-heme chloride peroxidase 834485..835288 Lactococcus lactis subsp. lactis Il1403 1114447 NP_266977.1 CDS yidE NC_002662.1 835448 835810 D hypothetical protein 835448..835810 Lactococcus lactis subsp. lactis Il1403 1114448 NP_266978.1 CDS tra904F NC_002662.1 835893 836654 R evidence experimental PMID:1328163; transposon related function; IS3/IS150/IS904 family transposase; transposase of IS904F complement(835893..836654) Lactococcus lactis subsp. lactis Il1403 1114449 NP_266979.1 CDS yidF NC_002662.1 836750 837040 R transposon related function; hypothetical protein complement(836750..837040) Lactococcus lactis subsp. lactis Il1403 1114450 NP_266980.1 CDS tra1077E NC_002662.1 837114 837932 R evidence experimental PMID:1328163; transposon related function. IS3/IS150/IS904 family transposase; IS1077E transposase complement(837114..837932) Lactococcus lactis subsp. lactis Il1403 1114451 NP_266981.1 CDS yidG NC_002662.1 837929 838486 R transposon related function; hypothetical protein complement(837929..838486) Lactococcus lactis subsp. lactis Il1403 1114452 NP_266982.1 CDS yidH NC_002662.1 838561 838851 D transposon related function; hypothetical protein 838561..838851 Lactococcus lactis subsp. lactis Il1403 1114453 NP_266983.1 CDS tra904G NC_002662.1 838947 839708 D evidence experimental PMID:1328163; transposon related function; IS3/IS150/IS904 family transposase; transposase of IS904G 838947..839708 Lactococcus lactis subsp. lactis Il1403 1114454 NP_266984.1 CDS noxA NC_002662.1 839911 841170 D aerobic energy metabolism; NADH dehydrogenase 839911..841170 Lactococcus lactis subsp. lactis Il1403 1114455 NP_266985.1 CDS noxB NC_002662.1 841314 843317 D aerobic energy metabolism; NADH dehydrogenase 841314..843317 Lactococcus lactis subsp. lactis Il1403 1114456 NP_266986.1 CDS sdaB NC_002662.1 843431 844102 D energy metabolism, amino acids and amines; gluconeogenesis; produces pyruvate; beta-subunit of L-serine dehydratase 843431..844102 Lactococcus lactis subsp. lactis Il1403 1114457 NP_266987.1 CDS sdaA NC_002662.1 844122 844985 D energy metabolism, amino acids and amines; gluconeogenesis; produces pyruvate; alpha-subuni L-serine dehydratase 844122..844985 Lactococcus lactis subsp. lactis Il1403 1114458 NP_266988.1 CDS copR NC_002662.1 845106 845561 D general regulatory function; transcriptional regulator 845106..845561 Lactococcus lactis subsp. lactis Il1403 1114459 NP_266989.1 CDS yieF NC_002662.1 845577 845777 D transport and binding protein, cations; similar to N-part of many mercuric reductases; probably involved in cation transport, because of the visinity of corresponding genes; mercuric reductase 845577..845777 Lactococcus lactis subsp. lactis Il1403 1114460 NP_266990.1 CDS copA NC_002662.1 845963 848125 D transort and binding protein, cations; copper/potassium-transporting ATPase 845963..848125 Lactococcus lactis subsp. lactis Il1403 1114461 NP_266991.1 CDS yieH NC_002662.1 848313 850964 R identified also as transmembrane protein Tmp5. similar to YfhO of Bacillus subtilis; hypothetical protein complement(848313..850964) Lactococcus lactis subsp. lactis Il1403 1114462 NP_266992.1 CDS yifA NC_002662.1 851035 851820 R hypothetical protein complement(851035..851820) Lactococcus lactis subsp. lactis Il1403 1114463 NP_266993.1 CDS mnmA NC_002662.1 852072 853226 D catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 852072..853226 Lactococcus lactis subsp. lactis Il1403 1114464 NP_266994.1 CDS rpsA NC_002662.1 853437 854663 D in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 853437..854663 Lactococcus lactis subsp. lactis Il1403 1114465 NP_266995.1 CDS udp NC_002662.1 854814 855530 D salvage of nucleosides and nucleotides; uridine phosphorylase 854814..855530 Lactococcus lactis subsp. lactis Il1403 1114466 NP_266996.1 CDS uvrC NC_002662.1 856467 858473 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 856467..858473 Lactococcus lactis subsp. lactis Il1403 1114468 NP_266997.1 CDS mutY NC_002662.1 858637 859800 D A/G-specific adenine glycosylase 858637..859800 Lactococcus lactis subsp. lactis Il1403 1114469 NP_266998.1 CDS pepV NC_002662.1 859866 861284 D divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases; dipeptidase PepV 859866..861284 Lactococcus lactis subsp. lactis Il1403 1114470 NP_266999.1 CDS acpS NC_002662.1 861387 861746 D Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 861387..861746 Lactococcus lactis subsp. lactis Il1403 1114471 NP_267000.1 CDS alr NC_002662.1 861791 862894 D converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 861791..862894 Lactococcus lactis subsp. lactis Il1403 1114472 NP_267001.1 CDS yigC NC_002662.1 863010 863438 D hypothetical protein 863010..863438 Lactococcus lactis subsp. lactis Il1403 1114473 NP_267002.1 CDS gshR NC_002662.1 863576 864883 D thioredoxin, glutaredoxin, and glutathione; glutathione reductase 863576..864883 Lactococcus lactis subsp. lactis Il1403 1114474 NP_267003.1 CDS choQ NC_002662.1 865009 865926 D transport and binding protein; amino acids, peptides and amines; maybe involved in osmoprotection; substrate can be also proline or glycine; choline ABC transporter ATP binding protein 865009..865926 Lactococcus lactis subsp. lactis Il1403 1114475 NP_267004.1 CDS choS NC_002662.1 865923 867425 D transport and binding protein; amino acids, peptides and amines; maybe involved in osmoprotection; substrate can be also proline or glycine; permease and substrate binding functions are in the same protein; choline ABC transporter permease and substrate binding protein 865923..867425 Lactococcus lactis subsp. lactis Il1403 1114476 NP_835303.1 CDS L200030 NC_002662.1 867714 869597 D hypothetical protein 867714..869597 Lactococcus lactis subsp. lactis Il1403 1114477 NP_267005.1 CDS yihA NC_002662.1 870129 870722 D hypothetical protein 870129..870722 Lactococcus lactis subsp. lactis Il1403 1114478 NP_267006.1 CDS yihB NC_002662.1 870719 871171 D hypothetical protein 870719..871171 Lactococcus lactis subsp. lactis Il1403 1114479 NP_267007.1 CDS copB NC_002662.1 871221 873308 R transort and binding protein, cations; copper-potassium transporting ATPase B complement(871221..873308) Lactococcus lactis subsp. lactis Il1403 1114480 NP_267008.1 CDS yihD NC_002662.1 873509 876700 D hypothetical protein 873509..876700 Lactococcus lactis subsp. lactis Il1403 1114481 NP_267009.1 CDS folD NC_002662.1 876830 877714 D catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 876830..877714 Lactococcus lactis subsp. lactis Il1403 1114482 NP_267010.1 CDS xseA NC_002662.1 877881 879134 D bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 877881..879134 Lactococcus lactis subsp. lactis Il1403 1114483 NP_267011.1 CDS xseB NC_002662.1 879134 879373 D catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 879134..879373 Lactococcus lactis subsp. lactis Il1403 1114484 NP_267012.1 CDS yihF NC_002662.1 879522 880679 D hypothetical protein 879522..880679 Lactococcus lactis subsp. lactis Il1403 1114485 NP_267013.1 CDS ispA NC_002662.1 880761 881618 D menaquinone and ubiquinone; side chain synthesis, also isoprenoid, carotenoid biosynthesis; belongs to a family that groups together FFP synthetase, GGPP synthetase and hexaprenyl pyrophosphate synthetase; farnesyl diphosphate synthase 880761..881618 Lactococcus lactis subsp. lactis Il1403 1114486 NP_267014.1 CDS yiiB NC_002662.1 881773 882504 D hemolysin-like protein; similar to hemolysin A; hypothetical protein 881773..882504 Lactococcus lactis subsp. lactis Il1403 1114487 NP_267015.1 CDS ahrC NC_002662.1 882501 882947 D similar to several AhrC proteins from different species; transcriptional regulator 882501..882947 Lactococcus lactis subsp. lactis Il1403 1114488 NP_267016.1 CDS recN NC_002662.1 883095 884762 D DNA replication, restriction, modification, recombination, and repair; may be involved in recombinational repair of damaged DNA; DNA repair protein RecN 883095..884762 Lactococcus lactis subsp. lactis Il1403 1114489 NP_267017.1 CDS yiiD NC_002662.1 884881 885111 D hypothetical protein 884881..885111 Lactococcus lactis subsp. lactis Il1403 1114490 NP_267018.1 CDS yiiE NC_002662.1 885488 886054 D hypothetical protein 885488..886054 Lactococcus lactis subsp. lactis Il1403 1114491 NP_267019.1 CDS yiiF NC_002662.1 886152 886673 D transport and binding protein; transporter 886152..886673 Lactococcus lactis subsp. lactis Il1403 1114492 NP_267020.1 CDS yiiG NC_002662.1 886696 887634 D hypothetical protein 886696..887634 Lactococcus lactis subsp. lactis Il1403 1114493 NP_267021.1 CDS mraW NC_002662.1 887854 888807 D S-adenosyl-methyltransferase MraW 887854..888807 Lactococcus lactis subsp. lactis Il1403 1114494 NP_267022.1 CDS yiiI NC_002662.1 888965 889345 D membrane protein; hypothetical protein 888965..889345 Lactococcus lactis subsp. lactis Il1403 1114495 NP_267023.1 CDS pbpX NC_002662.1 889342 891633 D cell envelope, murein sacculus and peptidoglycan; penicillin-binding protein 889342..891633 Lactococcus lactis subsp. lactis Il1403 1114496 NP_267024.1 CDS mraY NC_002662.1 891698 892687 D First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 891698..892687 Lactococcus lactis subsp. lactis Il1403 1114497 NP_267025.1 CDS yijB NC_002662.1 892887 893165 D hypothetical protein 892887..893165 Lactococcus lactis subsp. lactis Il1403 1114498 NP_267026.1 CDS yijC NC_002662.1 893298 894818 D transport and binding protein; ABC transporter permease 893298..894818 Lactococcus lactis subsp. lactis Il1403 1114499 NP_267028.1 CDS mleR NC_002662.1 895741 896616 D evidence experimental PMID:2498286; LysR-family regulators; malolactic fermentation system transcription activator 895741..896616 Lactococcus lactis subsp. lactis Il1403 1114502 NP_267029.1 CDS yijE NC_002662.1 896856 897530 D similar to YwaC of Bacillus subtilis; hypothetical protein 896856..897530 Lactococcus lactis subsp. lactis Il1403 1114503 NP_267030.1 CDS rplS NC_002662.1 897638 898015 D this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 897638..898015 Lactococcus lactis subsp. lactis Il1403 1114504 NP_267031.1 CDS yijF NC_002662.1 898311 898820 D hypothetical protein 898311..898820 Lactococcus lactis subsp. lactis Il1403 1114505 NP_267032.1 CDS yijG NC_002662.1 898813 900141 D surface polysaccharides, lipopolysaccharides and antigens; similar to intercellular adhesion locus protein IcaA of Staphylococcus epidermidis; glycosyl transferase family protein 898813..900141 Lactococcus lactis subsp. lactis Il1403 1114506 NP_267033.1 CDS yijH NC_002662.1 900367 900903 D hypothetical protein 900367..900903 Lactococcus lactis subsp. lactis Il1403 1114507 NP_267034.1 CDS pnuC2 NC_002662.1 901102 901833 D transport and binding protein; nucleosides, purines and pyrimidines; nicotinamide mononucleotide transporter 901102..901833 Lactococcus lactis subsp. lactis Il1403 1114508 NP_267035.1 CDS yjaB NC_002662.1 902361 902786 D hypothetical protein 902361..902786 Lactococcus lactis subsp. lactis Il1403 1114509 NP_267036.1 CDS hslB NC_002662.1 902908 903255 D DNA replication, restriction, modification, recombination, and repair; HU-like DNA-binding protein 902908..903255 Lactococcus lactis subsp. lactis Il1403 1114510 NP_267037.1 CDS yjaD NC_002662.1 903327 903860 R belongs to TetR/AcrR family; transcriptional regulator complement(903327..903860) Lactococcus lactis subsp. lactis Il1403 1114511 NP_267038.1 CDS yjaE NC_002662.1 904024 906423 D transmembrane protein, similar to phage infection protein Pip; hypothetical protein 904024..906423 Lactococcus lactis subsp. lactis Il1403 1114512 NP_267039.1 CDS yjaF NC_002662.1 906609 906941 D probably aromatic ring hydroxylating enzyme, evidenced by COGnitor; hypothetical protein 906609..906941 Lactococcus lactis subsp. lactis Il1403 1114513 NP_267040.1 CDS ftsW2 NC_002662.1 907791 908990 D cell division protein; similar to cell division protein FtsW of Enterococcus hirae; hypothetical protein 907791..908990 Lactococcus lactis subsp. lactis Il1403 1114514 NP_267044.1 CDS rpsN2 NC_002662.1 910421 910690 D 30S ribosomal protein S14 910421..910690 Lactococcus lactis subsp. lactis Il1403 1114518 NP_267045.1 CDS yjbB NC_002662.1 910856 911485 D hypothetical protein 910856..911485 Lactococcus lactis subsp. lactis Il1403 1114519 NP_267046.1 CDS kinD NC_002662.1 911482 912480 D evidence experimental PMID:9172368; two-component system; sensor protein kinase 911482..912480 Lactococcus lactis subsp. lactis Il1403 1114520 NP_267047.1 CDS llrD NC_002662.1 912508 913137 D evidence experimental PMID:10708382; two-component system; involved in salt and osmotic stress resistance development; two-component system regulator 912508..913137 Lactococcus lactis subsp. lactis Il1403 1114521 NP_267048.1 CDS yjbC NC_002662.1 913208 914014 D hypothetical protein 913208..914014 Lactococcus lactis subsp. lactis Il1403 1114522 NP_267049.1 CDS ppiB NC_002662.1 914117 914707 D translation; protein modification; peptidyl-prolyl cis-trans isomerase 914117..914707 Lactococcus lactis subsp. lactis Il1403 1114523 NP_267050.1 CDS yjbE NC_002662.1 914709 915140 D adaptations and atypical conditions; polyribonucleotide nucleotidyltransferase; general stress protein GSP13 914709..915140 Lactococcus lactis subsp. lactis Il1403 1114524 NP_267051.1 CDS yjbF NC_002662.1 915137 915742 D hypothetical protein 915137..915742 Lactococcus lactis subsp. lactis Il1403 1114525 NP_267052.1 CDS rodA NC_002662.1 915962 917206 D cell division; similar to rod-shape determining proteins from different species; rod-shape determining protein 915962..917206 Lactococcus lactis subsp. lactis Il1403 1114526 NP_267053.2 CDS butB NC_002662.1 917431 918501 D energy metabolism; fermentation; 2,3-butanediol dehydrogenase 917431..918501 Lactococcus lactis subsp. lactis Il1403 1114527 NP_267054.1 CDS butA NC_002662.1 918527 919288 D fermentation; acetoin reductase 918527..919288 Lactococcus lactis subsp. lactis Il1403 1114528 NP_267055.1 CDS yjcA NC_002662.1 919808 921349 D transport and binding protein; contains two ATP binding domains; ABC transporter ATP-binding protein 919808..921349 Lactococcus lactis subsp. lactis Il1403 1114529 NP_267056.1 CDS mleS NC_002662.1 921766 923388 D malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase 921766..923388 Lactococcus lactis subsp. lactis Il1403 1114530 NP_267057.1 CDS mleP NC_002662.1 923403 924680 D evidence experimental PMID:8405453; transport and binding protein; carbohydrates, organic alcohols and acids; malate transporter 923403..924680 Lactococcus lactis subsp. lactis Il1403 1114531 NP_267058.1 CDS yjcD NC_002662.1 924977 925909 D hypothetical protein 924977..925909 Lactococcus lactis subsp. lactis Il1403 1114532 NP_267059.1 CDS yjcE NC_002662.1 925990 927081 D hypothetical protein 925990..927081 Lactococcus lactis subsp. lactis Il1403 1114533 NP_267060.1 CDS yjcF NC_002662.1 927135 927782 D hypothetical protein 927135..927782 Lactococcus lactis subsp. lactis Il1403 1114534 NP_267061.1 CDS gyrB NC_002662.1 927935 929890 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 927935..929890 Lactococcus lactis subsp. lactis Il1403 1114535 NP_267062.1 CDS yjdA NC_002662.1 930397 931134 D hypothetical protein 930397..931134 Lactococcus lactis subsp. lactis Il1403 1114536 NP_267063.1 CDS yjdB NC_002662.1 931316 931921 D hypothetical protein 931316..931921 Lactococcus lactis subsp. lactis Il1403 1114537 NP_267064.1 CDS rmaH NC_002662.1 932070 932534 D MarR-family regulators; transcriptional regulator 932070..932534 Lactococcus lactis subsp. lactis Il1403 1114538 NP_267065.1 CDS yjdE NC_002662.1 932527 934071 D transport and binding protein; multidrug resistance protein 932527..934071 Lactococcus lactis subsp. lactis Il1403 1114539 NP_267066.1 CDS yjdF NC_002662.1 934071 934790 D hypothetical protein 934071..934790 Lactococcus lactis subsp. lactis Il1403 1114540 NP_267067.1 CDS tagR NC_002662.1 935545 935880 D similar to EpsR of the epsRXABCDEFGHIJKL operon of Lactococcus lactis plasmid pNZ4000; transcriptional regulator 935545..935880 Lactococcus lactis subsp. lactis Il1403 1114541 NP_267068.1 CDS tagL NC_002662.1 935988 936896 D surface polysaccharides, lipopolysaccharides and antigens; similar to EpsL protein of exopolysaccharide biosynthesis operons of S.thermophilus and l.lactis NIZO B35; exopolysaccharide biosynthesis protein 935988..936896 Lactococcus lactis subsp. lactis Il1403 1114542 NP_267069.1 CDS yjdI NC_002662.1 936920 937204 D hypothetical protein 936920..937204 Lactococcus lactis subsp. lactis Il1403 1114543 NP_267070.1 CDS yjdJ NC_002662.1 937270 937692 D transort and binding protein, cations; potassium channel protein 937270..937692 Lactococcus lactis subsp. lactis Il1403 1114544 NP_267071.1 CDS tagH NC_002662.1 937689 939089 D transport and binding protein, carbohydrates; organic alcohols and acids; teichoic acid ABC transporter ATP binding protein 937689..939089 Lactococcus lactis subsp. lactis Il1403 1114545 NP_267072.1 CDS tagG NC_002662.1 939089 939898 D transport and binding protein, carbohydrates; organic alcohols and acids; teichoic acid ABC transporter permease 939089..939898 Lactococcus lactis subsp. lactis Il1403 1114546 NP_267073.1 CDS yjeA NC_002662.1 939920 941362 D hypothetical protein 939920..941362 Lactococcus lactis subsp. lactis Il1403 1114547 NP_267074.1 CDS tagZ NC_002662.1 941343 944234 D surface polysaccharides, lipopolysaccharides and antigens; teichoic acid biosynthesis protein 941343..944234 Lactococcus lactis subsp. lactis Il1403 1114548 NP_267075.1 CDS tagY NC_002662.1 944247 944801 D surface polysaccharides, lipopolysaccharides and antigens; teichoic acid biosynthesis protein 944247..944801 Lactococcus lactis subsp. lactis Il1403 1114549 NP_267076.1 CDS yjeD NC_002662.1 944794 946425 D hypothetical protein 944794..946425 Lactococcus lactis subsp. lactis Il1403 1114550 NP_267077.1 CDS tagX NC_002662.1 946470 948893 D surface polysaccharides, lipopolysaccharides and antigens; teichoic acid biosynthesis protein 946470..948893 Lactococcus lactis subsp. lactis Il1403 1114551 NP_267078.1 CDS yjeF NC_002662.1 948942 949673 D surface polysaccharides, lipopolysaccharides and antigens; lipopolysaccharide biosynthesis protein 948942..949673 Lactococcus lactis subsp. lactis Il1403 1114552 NP_267079.1 CDS yjeG NC_002662.1 949844 950833 D hypothetical protein 949844..950833 Lactococcus lactis subsp. lactis Il1403 1114553 NP_267080.1 CDS tagD2 NC_002662.1 950851 951291 D surface polysaccharides, lipopolysaccharides and antigens; glycerol-3-phosphate cytidyltransferase 950851..951291 Lactococcus lactis subsp. lactis Il1403 1114554 NP_267081.1 CDS yjfB NC_002662.1 951328 951759 D hypothetical protein 951328..951759 Lactococcus lactis subsp. lactis Il1403 1114555 NP_267082.1 CDS tagF NC_002662.1 951780 952967 D surface polysaccharides, lipopolysaccharides and antigens; teichoic acid biosynthesis protein F 951780..952967 Lactococcus lactis subsp. lactis Il1403 1114556 NP_267083.1 CDS tagB NC_002662.1 952957 954072 D surface polysaccharides, lipopolysaccharides and antigens; teichoic acid biosynthesis protein B 952957..954072 Lactococcus lactis subsp. lactis Il1403 1114557 NP_267084.1 CDS yjfE NC_002662.1 954083 955003 D LytR family; transcriptional regulator 954083..955003 Lactococcus lactis subsp. lactis Il1403 1114558 NP_267085.1 CDS deoB NC_002662.1 955189 956424 D catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 955189..956424 Lactococcus lactis subsp. lactis Il1403 1114559 NP_267086.1 CDS yjfG NC_002662.1 956480 956749 D hypothetical protein 956480..956749 Lactococcus lactis subsp. lactis Il1403 1114560 NP_267087.1 CDS deoD NC_002662.1 956820 957524 D catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 956820..957524 Lactococcus lactis subsp. lactis Il1403 1114561 NP_267088.1 CDS tra983C NC_002662.1 957642 958589 D transposon related function; belongs to the IS30 family of transposase; transposase of IS983C 957642..958589 Lactococcus lactis subsp. lactis Il1403 1114562 NP_267089.1 CDS yjfI NC_002662.1 958745 959191 D hypothetical protein 958745..959191 Lactococcus lactis subsp. lactis Il1403 1114563 NP_267090.1 CDS yjfJ NC_002662.1 959275 959601 D hypothetical protein 959275..959601 Lactococcus lactis subsp. lactis Il1403 1114564 NP_267091.1 CDS fhs NC_002662.1 959757 961424 D catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase 959757..961424 Lactococcus lactis subsp. lactis Il1403 1114565 NP_267092.1 CDS yjgB NC_002662.1 961533 962126 D probably cell wall-associated hydrolase, evidenced by COGnitor; hypothetical protein 961533..962126 Lactococcus lactis subsp. lactis Il1403 1114566 NP_267093.1 CDS yjgC NC_002662.1 962264 963109 D transport and binding protein; amino acids, peptides and amines; amino acid ABC transporter substrate binding protein 962264..963109 Lactococcus lactis subsp. lactis Il1403 1114567 NP_267094.1 CDS yjgD NC_002662.1 963377 964264 D transport and binding protein; amino acids, peptides and amines; amino acid ABC transporter permease 963377..964264 Lactococcus lactis subsp. lactis Il1403 1114568 NP_267095.1 CDS yjgE NC_002662.1 964276 965028 D transport and binding protein; amino acids, peptides and amines; amino acid ABC transporter ATP binding protein 964276..965028 Lactococcus lactis subsp. lactis Il1403 1114569 NP_835305.1 CDS L200032 NC_002662.1 965033 965257 D hypothetical protein 965033..965257 Lactococcus lactis subsp. lactis Il1403 1114570 NP_267096.1 CDS trxB1 NC_002662.1 965452 966378 D thioredoxin, glutaredoxin, and glutathione; cofactor FAD flavoprotein; pyridine nucleotide-disulfide oxidoreductase class-II.; thioredoxin reductase 965452..966378 Lactococcus lactis subsp. lactis Il1403 1114571 NP_267097.1 CDS secG NC_002662.1 966520 966768 D protein and peptide secretion; involved in protein export; early event of protein translocation; preprotein translocase subunit SecG 966520..966768 Lactococcus lactis subsp. lactis Il1403 1114572 NP_267098.1 CDS vacB1 NC_002662.1 967019 969472 D degradation of RNA; ribonuclease II (RNB) family; ribonuclease 967019..969472 Lactococcus lactis subsp. lactis Il1403 1114573 NP_267099.1 CDS yjgF NC_002662.1 969491 970078 D probably amidase, evidenced by COGnitor; hypothetical protein 969491..970078 Lactococcus lactis subsp. lactis Il1403 1114574 NP_267100.1 CDS yjhA NC_002662.1 970158 971216 D hypothetical protein 970158..971216 Lactococcus lactis subsp. lactis Il1403 1114575 NP_267101.1 CDS yjhB NC_002662.1 971242 972183 R similar to 1,4-dihydroxy-2-naphthoate octaprenyltransferase of Bacillus subtilis; hypothetical protein complement(971242..972183) Lactococcus lactis subsp. lactis Il1403 1114576 NP_267102.1 CDS yjhC NC_002662.1 972337 972600 D ACT domain-containing protein; hypothetical protein 972337..972600 Lactococcus lactis subsp. lactis Il1403 1114577 NP_267103.1 CDS yjhD NC_002662.1 972717 974054 D similar to MJ1665 protein of Methanococcus jannaschii.; hypothetical protein 972717..974054 Lactococcus lactis subsp. lactis Il1403 1114578 NP_267104.1 CDS yjhE NC_002662.1 974154 974633 D hypothetical protein 974154..974633 Lactococcus lactis subsp. lactis Il1403 1114579 NP_267105.1 CDS yjhF NC_002662.1 974701 975396 D glycolysis; phosphoglycerate mutase 974701..975396 Lactococcus lactis subsp. lactis Il1403 1114580 NP_267106.1 CDS dacB NC_002662.1 975393 976139 D murein sacculus and peptidoglycan; in Enterococcus faecalis corresponding enzyme mediates vancomycin resistance; D-alanyl-D-alanine carboxypeptidase 975393..976139 Lactococcus lactis subsp. lactis Il1403 1114581 NP_267107.1 CDS yjhH NC_002662.1 976153 976557 D hypothetical protein 976153..976557 Lactococcus lactis subsp. lactis Il1403 1114582 NP_267108.1 CDS hrcA NC_002662.1 976778 977821 D Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 976778..977821 Lactococcus lactis subsp. lactis Il1403 1114583 NP_267109.1 CDS grpE NC_002662.1 977851 978390 D with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 977851..978390 Lactococcus lactis subsp. lactis Il1403 1114584 NP_267110.1 CDS dnaK NC_002662.1 978463 980286 D heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 978463..980286 Lactococcus lactis subsp. lactis Il1403 1114585 NP_267111.1 CDS mycA NC_002662.1 980498 982261 D in group A Streptococci this protein was found to cross react with anti myosin antibodies and may play a role in rheumatic fever; myosin-cross-reactive antigen 980498..982261 Lactococcus lactis subsp. lactis Il1403 1114586 NP_267112.1 CDS yjiB NC_002662.1 982328 983467 D energy metabolism, amino acids and amines; similar to several hippurate hydrolases and amino acid amidohydrolases; may be a peptidase; amino acid aminohydrolase 982328..983467 Lactococcus lactis subsp. lactis Il1403 1114587 NP_267113.1 CDS lacR NC_002662.1 983589 984290 D evidence experimental PMID:2120234; DeoR-family regulator; repressor of the lactose catabolism operon; galactose 6-phosphate is the inducer; lactose transport regulator 983589..984290 Lactococcus lactis subsp. lactis Il1403 1114588 NP_267114.1 CDS lacC NC_002662.1 984374 985291 D galactose metabolism; tagatose-6-phosphate kinase 984374..985291 Lactococcus lactis subsp. lactis Il1403 1114589 NP_267115.2 CDS fruA NC_002662.1 985291 987195 D transport and binding protein; PTS system; PTS system fructose-specific transporter subunit IIBC 985291..987195 Lactococcus lactis subsp. lactis Il1403 1114590 NP_267116.1 CDS clsA NC_002662.1 987282 988727 D membranes, lipoproteins, and porin; affects resistance to gyrase inhibitor novobiocin; condensationof two molecules of phosphatidylglycerol; cardiolipin synthase 987282..988727 Lactococcus lactis subsp. lactis Il1403 1114591 NP_267117.1 CDS yjiE NC_002662.1 988807 989694 D similar to YvcJ of Bacillus subtilis; hypothetical protein 988807..989694 Lactococcus lactis subsp. lactis Il1403 1114592 NP_267118.1 CDS yjiF NC_002662.1 989691 990674 D similar to YvcK of Bacillus subtilis; hypothetical protein 989691..990674 Lactococcus lactis subsp. lactis Il1403 1114593 NP_267119.1 CDS yjjA NC_002662.1 990778 991695 D similar to YvcL of Bacillus subtilis; hypothetical protein 990778..991695 Lactococcus lactis subsp. lactis Il1403 1114594 NP_267120.1 CDS yjjB NC_002662.1 991739 992296 R similar to tetR-family transcription regulators; transcriptional regulator complement(991739..992296) Lactococcus lactis subsp. lactis Il1403 1114595 NP_267121.1 CDS yjjC NC_002662.1 992452 993330 D transport and binding protein; ABC transporter ATP-binding protein 992452..993330 Lactococcus lactis subsp. lactis Il1403 1114596 NP_267122.1 CDS yjjD NC_002662.1 993341 994963 D transport and binding protein; ABC transporter permease 993341..994963 Lactococcus lactis subsp. lactis Il1403 1114597 NP_267123.1 CDS yjjE NC_002662.1 995105 995476 D hypothetical protein 995105..995476 Lactococcus lactis subsp. lactis Il1403 1114598 NP_267124.1 CDS yjjF NC_002662.1 995620 996414 D transport and binding protein; transporter 995620..996414 Lactococcus lactis subsp. lactis Il1403 1114599 NP_267125.1 CDS yjjG NC_002662.1 996445 996975 R similar to hypothetical YgaC protein from Bacillus subtilis; hypothetical protein complement(996445..996975) Lactococcus lactis subsp. lactis Il1403 1114600 YP_008998701.1 CDS L196207a NC_002662.1 997140 997310 R phosphohydrolase complement(997140..997310) Lactococcus lactis subsp. lactis Il1403 18245213 NP_267126.1 CDS yjjH NC_002662.1 997314 998045 R hypothetical protein complement(997314..998045) Lactococcus lactis subsp. lactis Il1403 1114601 NP_267127.1 CDS prfB NC_002662.1 998162 999259 D recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 998162..999259 Lactococcus lactis subsp. lactis Il1403 1114602 NP_267128.1 CDS ftsE NC_002662.1 999586 1000278 D cell division; cell-division ATP-binding protein 999586..1000278 Lactococcus lactis subsp. lactis Il1403 1114603 NP_267129.1 CDS ftsX NC_002662.1 1000271 1001206 D cell division; cell division protein 1000271..1001206 Lactococcus lactis subsp. lactis Il1403 1114604 NP_267130.1 CDS nrdF NC_002662.1 1001308 1002285 R B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta complement(1001308..1002285) Lactococcus lactis subsp. lactis Il1403 1114605 NP_267131.1 CDS nrdE NC_002662.1 1002635 1004803 R Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha complement(1002635..1004803) Lactococcus lactis subsp. lactis Il1403 1114606 NP_267132.1 CDS nrdI NC_002662.1 1004939 1005361 R in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein complement(1004939..1005361) Lactococcus lactis subsp. lactis Il1403 1114607 NP_267133.1 CDS ndrH NC_002662.1 1005363 1005539 R glutaredoxin-like protein; energy metabolism, electron transport; electron transport system for ribonucleotide reductase system NrdEF; NrdH complement(1005363..1005539) Lactococcus lactis subsp. lactis Il1403 1114608 NP_267134.1 CDS ykaC NC_002662.1 1005755 1006396 R involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY complement(1005755..1006396) Lactococcus lactis subsp. lactis Il1403 1114609 NP_267135.1 CDS parE NC_002662.1 1006671 1008605 D decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 1006671..1008605 Lactococcus lactis subsp. lactis Il1403 1114610 NP_267136.1 CDS ykaE NC_002662.1 1008810 1009016 D hypothetical protein 1008810..1009016 Lactococcus lactis subsp. lactis Il1403 1114611 NP_267137.1 CDS ykaF NC_002662.1 1009013 1009348 D hypothetical protein 1009013..1009348 Lactococcus lactis subsp. lactis Il1403 1114612 NP_267138.1 CDS dnaQ NC_002662.1 1009341 1010174 D DNA replication, restriction, modification, recombination, and repair; exhibits 3' to 5' exonuclease activity; DNA polymerase III subunit epsilon 1009341..1010174 Lactococcus lactis subsp. lactis Il1403 1114613 NP_267139.1 CDS ykbA NC_002662.1 1010171 1010620 D hypothetical protein 1010171..1010620 Lactococcus lactis subsp. lactis Il1403 1114614 NP_267140.1 CDS parC NC_002662.1 1010895 1013369 D decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 1010895..1013369 Lactococcus lactis subsp. lactis Il1403 1114615 NP_267141.1 CDS ykbB NC_002662.1 1013395 1014300 R hypothetical protein complement(1013395..1014300) Lactococcus lactis subsp. lactis Il1403 1114616 NP_267142.1 CDS ykbC NC_002662.1 1014515 1017796 D hypothetical protein 1014515..1017796 Lactococcus lactis subsp. lactis Il1403 1114617 NP_267143.1 CDS ykbD NC_002662.1 1017796 1018389 D hypothetical protein 1017796..1018389 Lactococcus lactis subsp. lactis Il1403 1114618 NP_267144.1 CDS ykbE NC_002662.1 1018394 1018945 D hypothetical protein 1018394..1018945 Lactococcus lactis subsp. lactis Il1403 1114619 NP_267145.1 CDS ykbF NC_002662.1 1019058 1019720 D hypothetical protein 1019058..1019720 Lactococcus lactis subsp. lactis Il1403 1114620 NP_267146.1 CDS ykcA NC_002662.1 1019770 1020381 D hypothetical protein 1019770..1020381 Lactococcus lactis subsp. lactis Il1403 1114621 NP_267147.1 CDS ykcB NC_002662.1 1020378 1021055 D hypothetical protein 1020378..1021055 Lactococcus lactis subsp. lactis Il1403 1114622 NP_267148.1 CDS ykcC NC_002662.1 1021071 1021496 D hypothetical protein 1021071..1021496 Lactococcus lactis subsp. lactis Il1403 1114623 NP_267149.1 CDS ribG NC_002662.1 1022028 1023116 D riboflavin and cobalamin; converts 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1H,3H)-pyrimidinone 5'-phosphate; riboflavin-specific deaminase 1022028..1023116 Lactococcus lactis subsp. lactis Il1403 1114624 NP_267150.1 CDS ribB NC_002662.1 1023116 1023766 D catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1023116..1023766 Lactococcus lactis subsp. lactis Il1403 1114625 NP_267151.1 CDS ribA NC_002662.1 1023775 1024971 D riboflavin and cobalamin; GTP cyclohydrolase II; 3,4-dihydroxy-2-butanone 4-phosphate synthase 1023775..1024971 Lactococcus lactis subsp. lactis Il1403 1114626 NP_267152.1 CDS ribH NC_002662.1 1024999 1025463 D RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 1024999..1025463 Lactococcus lactis subsp. lactis Il1403 1114627 NP_267153.1 CDS lspA NC_002662.1 1025566 1026018 D lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 1025566..1026018 Lactococcus lactis subsp. lactis Il1403 1114628 NP_267154.1 CDS rluD NC_002662.1 1026079 1026984 D RNA synthesis, modification, and DNA transcription; responsible for synthesis of pseudouridine from uracil-2650 in 23S ribosomal RNA; belongs to family two of pseudouridine synthases; ribosomal large subunit pseudouridine synthase D 1026079..1026984 Lactococcus lactis subsp. lactis Il1403 1114629 NP_267155.1 CDS ykcE NC_002662.1 1027131 1027574 D hypothetical protein 1027131..1027574 Lactococcus lactis subsp. lactis Il1403 1114630 NP_267156.1 CDS ykcF NC_002662.1 1027714 1029315 D hypothetical protein 1027714..1029315 Lactococcus lactis subsp. lactis Il1403 1114631 NP_267157.1 CDS ykcG NC_002662.1 1029339 1030295 D hypothetical protein 1029339..1030295 Lactococcus lactis subsp. lactis Il1403 1114632 NP_267158.1 CDS llrE NC_002662.1 1030421 1031107 D evidence experimental PMID:10708382; two-component system; involved in phosphatase expression; two-component system regulator 1030421..1031107 Lactococcus lactis subsp. lactis Il1403 1114633 NP_267159.1 CDS ykdA NC_002662.1 1031127 1031642 D hypothetical protein 1031127..1031642 Lactococcus lactis subsp. lactis Il1403 1114634 NP_267160.1 CDS kinE NC_002662.1 1031646 1032971 D evidence experimental PMID:9172368; two-component systems; sensor protein kinase 1031646..1032971 Lactococcus lactis subsp. lactis Il1403 1114635 NP_267161.1 CDS ykdB NC_002662.1 1032978 1033634 D probably phosphatase, evidenced by COGnitor; hypothetical protein 1032978..1033634 Lactococcus lactis subsp. lactis Il1403 1114636 NP_267162.1 CDS glmS NC_002662.1 1033815 1035632 D Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 1033815..1035632 Lactococcus lactis subsp. lactis Il1403 1114637 NP_267163.1 CDS radC NC_002662.1 1035763 1036443 D Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 1035763..1036443 Lactococcus lactis subsp. lactis Il1403 1114638 NP_267164.1 CDS pi201 NC_002662.1 1036642 1037766 R prophage pi2 protein 01; similar to integrase of Lactococcus lactis phage BK5-T; integrase complement(1036642..1037766) Lactococcus lactis subsp. lactis Il1403 1114639 NP_267165.1 CDS pi202 NC_002662.1 1037889 1038434 R similar to Orf3 of bacteriophage TP901-1; prophage pi2 protein 02 complement(1037889..1038434) Lactococcus lactis subsp. lactis Il1403 1114640 NP_267166.1 CDS pi203 NC_002662.1 1038491 1038928 R similar to Orf2 of bacteriophage TP901-1; prophage pi2 protein 03 complement(1038491..1038928) Lactococcus lactis subsp. lactis Il1403 1114641 NP_267167.1 CDS pi204 NC_002662.1 1038925 1039467 R prophage pi2 protein 04; similar to Orf4 of bacteriophage TP901-1; cI-like repressor complement(1038925..1039467) Lactococcus lactis subsp. lactis Il1403 1114642 NP_267168.1 CDS pi205 NC_002662.1 1039635 1039853 D similar to Orf5 of bacteriophage TP901-1; prophage pi2 protein 05 1039635..1039853 Lactococcus lactis subsp. lactis Il1403 1114643 NP_267169.1 CDS pi206 NC_002662.1 1039890 1040633 D similar to Orf6 of bacteriophage TP901-1; prophage pi2 protein 06 1039890..1040633 Lactococcus lactis subsp. lactis Il1403 1114644 NP_267170.1 CDS pi207 NC_002662.1 1040646 1040981 D similar to Orf111 of bacteriophage BK5-T; prophage pi2 protein 07 1040646..1040981 Lactococcus lactis subsp. lactis Il1403 1114645 NP_835341.1 CDS L200033 NC_002662.1 1041119 1041313 D similar to prophage pi3 protein 53; hypothetical protein 1041119..1041313 Lactococcus lactis subsp. lactis Il1403 1114646 NP_267171.1 CDS pi208 NC_002662.1 1041310 1041585 R similar to Orf10 of bacteriophage Tuc2009; prophage pi2 protein 08 complement(1041310..1041585) Lactococcus lactis subsp. lactis Il1403 1114647 NP_267172.1 CDS pi209 NC_002662.1 1041688 1041903 D similar to Orf71 of bacteriophage phi31; prophage pi2 protein 09 1041688..1041903 Lactococcus lactis subsp. lactis Il1403 1114648 NP_267173.1 CDS pi210 NC_002662.1 1042019 1042537 D similar to Orf13 of bacteriophage Tuc2009; prophage pi2 protein 10 1042019..1042537 Lactococcus lactis subsp. lactis Il1403 1114649 NP_267174.1 CDS pi211 NC_002662.1 1042546 1043169 D prophage pi2 protein 11; similar to topoisomerase I of bacteriophage Tuc2009; topoisomerase 1042546..1043169 Lactococcus lactis subsp. lactis Il1403 1114650 NP_267175.1 CDS pi212 NC_002662.1 1043169 1043621 D prophage pi2 protein 12; single strand binding protein 1043169..1043621 Lactococcus lactis subsp. lactis Il1403 1114651 NP_267176.1 CDS pi213 NC_002662.1 1043761 1044528 D prophage pi2 protein 13; similar to Rep2009 of bacteriophage Tuc2009; replisome organizer 1043761..1044528 Lactococcus lactis subsp. lactis Il1403 1114652 NP_267177.1 CDS pi214 NC_002662.1 1044528 1045253 D similar to Orf17 of bacteriophage Tuc2009; hypothetical protein 1044528..1045253 Lactococcus lactis subsp. lactis Il1403 1114653 NP_267178.1 CDS pi215 NC_002662.1 1045250 1045639 D similar to Orf19 of bacteriophage Tuc2009; prophage pi2 protein 15 1045250..1045639 Lactococcus lactis subsp. lactis Il1403 1114654 NP_267179.1 CDS pi216 NC_002662.1 1045642 1045836 D similar to Orf15 of bacteriophage r1t; prophage pi2 protein 16 1045642..1045836 Lactococcus lactis subsp. lactis Il1403 1114655 NP_835306.1 CDS L200034 NC_002662.1 1045817 1046068 D similar to prophage pi3 protein 43; hypothetical protein 1045817..1046068 Lactococcus lactis subsp. lactis Il1403 1114656 NP_267180.1 CDS pi217 NC_002662.1 1046180 1046446 D prophage pi2 protein 17 1046180..1046446 Lactococcus lactis subsp. lactis Il1403 1114657 NP_835342.1 CDS L200035 NC_002662.1 1046468 1046647 D similar to prophage pi3 protein 41; hypothetical protein 1046468..1046647 Lactococcus lactis subsp. lactis Il1403 1114658 NP_267181.1 CDS pi218 NC_002662.1 1046637 1047206 D similar to Orf22 of bacteriophage Tuc2009; prophage pi2 protein 18 1046637..1047206 Lactococcus lactis subsp. lactis Il1403 1114659 NP_835343.1 CDS L200036 NC_002662.1 1047400 1047606 D similar to prophage pi1 protein 17; hypothetical protein 1047400..1047606 Lactococcus lactis subsp. lactis Il1403 1114660 NP_267182.1 CDS pi219 NC_002662.1 1047599 1047871 D prophage pi2 protein 19 1047599..1047871 Lactococcus lactis subsp. lactis Il1403 1114661 NP_267183.1 CDS pi220 NC_002662.1 1047868 1048422 D similar to Orf24 of bacteriophage Tuc2009; prophage pi2 protein 20 1047868..1048422 Lactococcus lactis subsp. lactis Il1403 1114662 NP_267184.1 CDS pi221 NC_002662.1 1048419 1048838 D prophage pi2 protein 21; de novo synthesis of thymidylate; similar to dUTPase of bacteriophage r1t; deoxyuridine 5'-triphosphate nucleotidohydrolase 1048419..1048838 Lactococcus lactis subsp. lactis Il1403 1114663 NP_267185.1 CDS pi222 NC_002662.1 1048841 1049338 D prophage pi2 protein 22 1048841..1049338 Lactococcus lactis subsp. lactis Il1403 1114664 NP_267186.1 CDS pi223 NC_002662.1 1049328 1049675 D prophage pi2 protein 23 1049328..1049675 Lactococcus lactis subsp. lactis Il1403 1114665 NP_835307.1 CDS L200037 NC_002662.1 1049697 1049861 D similar to bacteriophage bIL285 Orf31; hypothetical protein 1049697..1049861 Lactococcus lactis subsp. lactis Il1403 1114666 NP_835308.1 CDS L200038 NC_002662.1 1049908 1050093 D similar to bacteriophage bIL285 Orf32; hypothetical protein 1049908..1050093 Lactococcus lactis subsp. lactis Il1403 1114667 NP_835309.1 CDS L200039 NC_002662.1 1050135 1050308 D similar to bacteriophage bIL285 Orf33; hypothetical protein 1050135..1050308 Lactococcus lactis subsp. lactis Il1403 1114668 NP_267187.1 CDS pi224 NC_002662.1 1050309 1050608 D prophage pi2 protein 24 1050309..1050608 Lactococcus lactis subsp. lactis Il1403 1114669 NP_835310.1 CDS L200040 NC_002662.1 1050605 1050787 D similar to bacteriophage bIL285 Orf35; hypothetical protein 1050605..1050787 Lactococcus lactis subsp. lactis Il1403 1114670 NP_267188.1 CDS pi225 NC_002662.1 1050725 1050988 R prophage pi2 protein 25 complement(1050725..1050988) Lactococcus lactis subsp. lactis Il1403 1114671 NP_267189.1 CDS pi226 NC_002662.1 1051151 1051444 D similar to Lactococcus lactis S114 hypothetical protein accession number Y11901; prophage pi2 protein 26 1051151..1051444 Lactococcus lactis subsp. lactis Il1403 1114672 NP_267190.1 CDS pi227 NC_002662.1 1051522 1051923 D prophage pi2 protein 27 1051522..1051923 Lactococcus lactis subsp. lactis Il1403 1114673 NP_267191.2 CDS pi228 NC_002662.1 1052187 1052486 D HNH endonuclease 1052187..1052486 Lactococcus lactis subsp. lactis Il1403 1114674 NP_267192.1 CDS pi229 NC_002662.1 1052578 1052946 D prophage pi2 protein 29 1052578..1052946 Lactococcus lactis subsp. lactis Il1403 1114675 NP_267193.1 CDS pi230 NC_002662.1 1052930 1054708 D prophage pi2 protein 30; similar to Orf22 of bacteriophage phi-105; terminase 1052930..1054708 Lactococcus lactis subsp. lactis Il1403 1114676 NP_267194.1 CDS pi231 NC_002662.1 1054722 1055927 D prophage pi2 protein 31 1054722..1055927 Lactococcus lactis subsp. lactis Il1403 1114677 NP_267195.1 CDS pi232 NC_002662.1 1055942 1056538 D similar to Orf26 of bacteriophage phi-105; prophage pi2 protein 32 1055942..1056538 Lactococcus lactis subsp. lactis Il1403 1114678 NP_267196.1 CDS pi233 NC_002662.1 1056510 1057703 D prophage pi2 protein 33; similar to capsid protein of S.aureus bacteriophage phi PVL; capsid protein 1056510..1057703 Lactococcus lactis subsp. lactis Il1403 1114679 NP_267197.1 CDS pi234 NC_002662.1 1057758 1058615 D prophage pi2 protein 34 1057758..1058615 Lactococcus lactis subsp. lactis Il1403 1114680 NP_267198.1 CDS pi235 NC_002662.1 1058608 1058889 D prophage pi2 protein 35 1058608..1058889 Lactococcus lactis subsp. lactis Il1403 1114681 NP_267199.1 CDS pi236 NC_002662.1 1058876 1059193 D prophage pi2 protein 36 1058876..1059193 Lactococcus lactis subsp. lactis Il1403 1114682 NP_267200.1 CDS pi237 NC_002662.1 1059183 1059554 D prophage pi2 protein 37 1059183..1059554 Lactococcus lactis subsp. lactis Il1403 1114683 NP_267201.1 CDS pi238 NC_002662.1 1059551 1059868 D prophage pi2 protein 38 1059551..1059868 Lactococcus lactis subsp. lactis Il1403 1114684 NP_267202.1 CDS pi239 NC_002662.1 1059886 1060494 D similar to Orf34 of Bacillus subtilis bacteriophage phi-105; prophage pi2 protein 39 1059886..1060494 Lactococcus lactis subsp. lactis Il1403 1114685 NP_267203.1 CDS pi240 NC_002662.1 1060504 1060863 D prophage pi2 protein 40 1060504..1060863 Lactococcus lactis subsp. lactis Il1403 1114686 NP_267204.1 CDS pi241 NC_002662.1 1060890 1061066 D prophage pi2 protein 41 1060890..1061066 Lactococcus lactis subsp. lactis Il1403 1114687 NP_267205.1 CDS pi242 NC_002662.1 1061080 1063341 D similar to protein l16 of bacteriophage bil170; prophage pi2 protein 42 1061080..1063341 Lactococcus lactis subsp. lactis Il1403 1114688 NP_267206.1 CDS pi243 NC_002662.1 1063342 1064091 D similar to Orf247 of Lactobacillus gasseri bacteriophage phi adh; prophage pi2 protein 43 1063342..1064091 Lactococcus lactis subsp. lactis Il1403 1114689 NP_267207.1 CDS pi244 NC_002662.1 1064088 1066772 D similar to a part of hypothetical protein BB0262 of Borrelia burgdorferi; prophage pi2 protein 44 1064088..1066772 Lactococcus lactis subsp. lactis Il1403 1114690 NP_267208.1 CDS pi245 NC_002662.1 1066785 1068386 D prophage pi2 protein 45 1066785..1068386 Lactococcus lactis subsp. lactis Il1403 1114691 NP_267209.1 CDS pi246 NC_002662.1 1068379 1069209 D prophage pi2 protein 46 1068379..1069209 Lactococcus lactis subsp. lactis Il1403 1114692 NP_267210.1 CDS pi247 NC_002662.1 1069268 1069675 D prophage pi2 protein 47 1069268..1069675 Lactococcus lactis subsp. lactis Il1403 1114693 NP_267211.1 CDS pi248 NC_002662.1 1069662 1070000 D prophage pi2 protein 48 1069662..1070000 Lactococcus lactis subsp. lactis Il1403 1114694 NP_267212.1 CDS pi249 NC_002662.1 1070002 1070229 D prophage pi2 protein 49 1070002..1070229 Lactococcus lactis subsp. lactis Il1403 1114695 NP_267213.1 CDS pi250 NC_002662.1 1070255 1070479 D similar to Orf75 of Lactococcus lactis phage BK5-T; prophage pi2 protein 50 1070255..1070479 Lactococcus lactis subsp. lactis Il1403 1114696 NP_267216.1 CDS ykhD NC_002662.1 1072170 1072709 R modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor Rex complement(1072170..1072709) Lactococcus lactis subsp. lactis Il1403 1114699 NP_267217.1 CDS ykhE NC_002662.1 1072934 1073326 D hypothetical protein 1072934..1073326 Lactococcus lactis subsp. lactis Il1403 1114700 NP_267218.1 CDS ykhF NC_002662.1 1073504 1075411 D transport and binding protein. contains two ATP binding domains; ABC transporter ATP-binding protein 1073504..1075411 Lactococcus lactis subsp. lactis Il1403 1114701 NP_267219.1 CDS ykhG NC_002662.1 1075600 1076400 D hypothetical protein 1075600..1076400 Lactococcus lactis subsp. lactis Il1403 1114702 NP_267220.1 CDS ykhH NC_002662.1 1076402 1076767 D hypothetical protein 1076402..1076767 Lactococcus lactis subsp. lactis Il1403 1114703 NP_267221.1 CDS ykhJ NC_002662.1 1077255 1077581 R hypothetical protein complement(1077255..1077581) Lactococcus lactis subsp. lactis Il1403 1114704 NP_835311.1 CDS L200041 NC_002662.1 1077283 1077468 D hypothetical protein 1077283..1077468 Lactococcus lactis subsp. lactis Il1403 1114705 NP_267222.1 CDS ykhI NC_002662.1 1077643 1078500 D similar to positive regulator GadR of Lactococcus lactis; transcriptional regulator 1077643..1078500 Lactococcus lactis subsp. lactis Il1403 1114706 NP_267223.1 CDS ykhK NC_002662.1 1078747 1079478 D hypothetical protein 1078747..1079478 Lactococcus lactis subsp. lactis Il1403 1114707 NP_267224.1 CDS pyrE NC_002662.1 1080700 1081329 D involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 1080700..1081329 Lactococcus lactis subsp. lactis Il1403 1114708 NP_267225.1 CDS pyrC NC_002662.1 1081430 1082755 D catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 1081430..1082755 Lactococcus lactis subsp. lactis Il1403 1114709 NP_267226.1 CDS dnaD NC_002662.1 1083162 1083830 D component of primosome; hypothetical protein 1083162..1083830 Lactococcus lactis subsp. lactis Il1403 1114710 NP_267227.1 CDS nth NC_002662.1 1083852 1084508 D degradation of DNA; endonucleolytic cleavage near apurinic or apyrimidinic sites to products with 5'-phosphate; endonuclease III 1083852..1084508 Lactococcus lactis subsp. lactis Il1403 1114711 NP_267228.1 CDS ykiC NC_002662.1 1084501 1085193 D hypothetical protein 1084501..1085193 Lactococcus lactis subsp. lactis Il1403 1114712 NP_267229.1 CDS ykiD NC_002662.1 1085190 1085963 D hypothetical protein 1085190..1085963 Lactococcus lactis subsp. lactis Il1403 1114713 NP_267230.1 CDS ykiE NC_002662.1 1086002 1086367 R hypothetical protein complement(1086002..1086367) Lactococcus lactis subsp. lactis Il1403 1114714 NP_267231.1 CDS ykiF NC_002662.1 1086489 1087304 R hypothetical protein complement(1086489..1087304) Lactococcus lactis subsp. lactis Il1403 1114715 NP_267232.1 CDS ykiG NC_002662.1 1087351 1088712 R hypothetical protein complement(1087351..1088712) Lactococcus lactis subsp. lactis Il1403 1114716 NP_267233.1 CDS ykiH NC_002662.1 1088881 1089288 D hypothetical protein 1088881..1089288 Lactococcus lactis subsp. lactis Il1403 1114717 NP_267234.1 CDS ykiI NC_002662.1 1089281 1090456 D hypothetical protein 1089281..1090456 Lactococcus lactis subsp. lactis Il1403 1114718 NP_267235.1 CDS rplU NC_002662.1 1090626 1090940 D ribosomal proteins; synthesis and modification; binds 23S rRNA in presence of protein L20; L21P family of ribosomal proteins; 50S ribosomal protein L21 1090626..1090940 Lactococcus lactis subsp. lactis Il1403 1114719 NP_267236.1 CDS ykjA NC_002662.1 1090943 1091278 D hypothetical protein 1090943..1091278 Lactococcus lactis subsp. lactis Il1403 1114720 NP_267237.1 CDS rpmA NC_002662.1 1091280 1091564 D involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 1091280..1091564 Lactococcus lactis subsp. lactis Il1403 1114721 NP_267240.1 CDS phoL NC_002662.1 1093130 1094098 D adaptations and atypical conditions; phosphate starvation inducible protein 1093130..1094098 Lactococcus lactis subsp. lactis Il1403 1114724 NP_267241.1 CDS ykjE NC_002662.1 1094156 1094635 D probably ADP-ribose pyrophosphatase or mutT, evidenced by COGnitor; hypothetical protein 1094156..1094635 Lactococcus lactis subsp. lactis Il1403 1114725 NP_267242.1 CDS ykjF NC_002662.1 1094787 1095275 D metalloprotease 1094787..1095275 Lactococcus lactis subsp. lactis Il1403 1114726 NP_267243.1 CDS dgkA NC_002662.1 1095259 1095714 D diacylglycerol kinase 1095259..1095714 Lactococcus lactis subsp. lactis Il1403 1114727 NP_267244.1 CDS ykjH NC_002662.1 1095728 1096306 D hypothetical protein 1095728..1096306 Lactococcus lactis subsp. lactis Il1403 1114728 NP_267245.1 CDS comFC NC_002662.1 1096340 1096990 R competence protein; transformation; ATP-dependent RNA/DNA helicase involved in DNA transport; hypothetical protein complement(1096340..1096990) Lactococcus lactis subsp. lactis Il1403 1114729 NP_267246.1 CDS comFA NC_002662.1 1096987 1098309 R competence protein; transformation; ATP-dependent RNA/DNA helicase involved in DNA transport; protein ComFA complement(1096987..1098309) Lactococcus lactis subsp. lactis Il1403 1114730 NP_267247.1 CDS ykjI NC_002662.1 1098366 1098995 D hypothetical protein 1098366..1098995 Lactococcus lactis subsp. lactis Il1403 1114731 NP_267248.1 CDS ykjJ NC_002662.1 1099129 1099626 D similar to teicoplanin resistance protein of transposon Tn1546 of Enterococcus faecium; hypothetical protein 1099129..1099626 Lactococcus lactis subsp. lactis Il1403 1114732 NP_267249.1 CDS ykjK NC_002662.1 1099674 1100693 D integral membrane protein; hypothetical protein 1099674..1100693 Lactococcus lactis subsp. lactis Il1403 1114733 NP_267250.1 CDS nucA NC_002662.1 1100803 1101555 D nucleotide and nucleoside interconversions; nucleotidase 1100803..1101555 Lactococcus lactis subsp. lactis Il1403 1114734 NP_267251.1 CDS glyQ NC_002662.1 1101840 1102793 D glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 1101840..1102793 Lactococcus lactis subsp. lactis Il1403 1114735 NP_267252.1 CDS glyS NC_002662.1 1102793 1104814 D glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 1102793..1104814 Lactococcus lactis subsp. lactis Il1403 1114736 NP_267253.1 CDS ylaC NC_002662.1 1104925 1105167 D hypothetical protein 1104925..1105167 Lactococcus lactis subsp. lactis Il1403 1114737 NP_267254.1 CDS ylaD NC_002662.1 1105378 1106589 D hypothetical protein 1105378..1106589 Lactococcus lactis subsp. lactis Il1403 1114738 NP_267255.1 CDS nadD NC_002662.1 1106612 1107199 R transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase complement(1106612..1107199) Lactococcus lactis subsp. lactis Il1403 1114739 NP_267256.1 CDS ylaF NC_002662.1 1107724 1109211 D catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 1107724..1109211 Lactococcus lactis subsp. lactis Il1403 1114740 NP_267257.1 CDS ylaG NC_002662.1 1109208 1109696 D hypothetical protein 1109208..1109696 Lactococcus lactis subsp. lactis Il1403 1114741 NP_267258.1 CDS nadE NC_002662.1 1109757 1110581 D catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 1109757..1110581 Lactococcus lactis subsp. lactis Il1403 1114742 NP_267259.1 CDS ylbA NC_002662.1 1110709 1111410 D transport and binding protein; ABC transporter ATP-binding protein 1110709..1111410 Lactococcus lactis subsp. lactis Il1403 1114743 NP_267260.1 CDS ylbB NC_002662.1 1111404 1114094 D transport and binding protein; ABC transporter permease 1111404..1114094 Lactococcus lactis subsp. lactis Il1403 1114744 NP_267261.1 CDS cobQ NC_002662.1 1114170 1114955 R riboflavin and cobalamin; similar to cobyric acid synthase CobQ of Heliobacillus mobilis, cobalamin biosynthesis pathway; cobyric acid synthase complement(1114170..1114955) Lactococcus lactis subsp. lactis Il1403 1114745 NP_267262.1 CDS ylbD NC_002662.1 1114956 1116305 R similar to UDP-N-acetylmuramyl tripeptide synthetase MurC of Heliobacillus mobilis; hypothetical protein complement(1114956..1116305) Lactococcus lactis subsp. lactis Il1403 1114746 NP_267263.1 CDS aldC NC_002662.1 1116416 1117081 D fermentation; converts acetolactate into actoin or diacetyl; alpha-acetolactate decarboxylase 1116416..1117081 Lactococcus lactis subsp. lactis Il1403 1114747 NP_267264.1 CDS lepA NC_002662.1 1117368 1119191 D binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 1117368..1119191 Lactococcus lactis subsp. lactis Il1403 1114748 NP_267265.1 CDS ylbE NC_002662.1 1119258 1119893 D anaerobic energy metabolism; similar to YhfK of Bacillus subtilis and to several hypothetical proteins; oxidoreductase 1119258..1119893 Lactococcus lactis subsp. lactis Il1403 1114749 NP_267266.1 CDS ylcA NC_002662.1 1120067 1121533 D transport and binding protein; amino acids, peptides and amines; amino acid permease 1120067..1121533 Lactococcus lactis subsp. lactis Il1403 1114750 NP_267267.1 CDS gyrA NC_002662.1 1121779 1124268 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 1121779..1124268 Lactococcus lactis subsp. lactis Il1403 1114751 NP_267268.1 CDS apbE NC_002662.1 1124352 1125437 D thiamine biosynthesis lipoprotein 1124352..1125437 Lactococcus lactis subsp. lactis Il1403 1114752 NP_267269.1 CDS ylcC NC_002662.1 1125438 1126301 D probably an integral membrane protein; hypothetical protein 1125438..1126301 Lactococcus lactis subsp. lactis Il1403 1114753 NP_267270.1 CDS ylcD NC_002662.1 1126413 1127852 D hypothetical protein 1126413..1127852 Lactococcus lactis subsp. lactis Il1403 1114754 NP_267271.1 CDS ylcE NC_002662.1 1127867 1128148 D hypothetical protein 1127867..1128148 Lactococcus lactis subsp. lactis Il1403 1114755 NP_267272.1 CDS ylcF NC_002662.1 1128168 1129412 D hypothetical protein 1128168..1129412 Lactococcus lactis subsp. lactis Il1403 1114756 NP_267273.1 CDS ylcG NC_002662.1 1129534 1132299 D probably an integral membrane protein; C-part similar to lysyl tRNA synthetase; hypothetical protein 1129534..1132299 Lactococcus lactis subsp. lactis Il1403 1114757 NP_267274.1 CDS yldA NC_002662.1 1132286 1132915 D hypothetical protein 1132286..1132915 Lactococcus lactis subsp. lactis Il1403 1114758 NP_267275.1 CDS yldB NC_002662.1 1132860 1133636 R hypothetical protein complement(1132860..1133636) Lactococcus lactis subsp. lactis Il1403 1114759 NP_267276.1 CDS pcrA NC_002662.1 1133793 1136069 D UvrD subfamily of helicases; ATP-dependent helicase PcrA 1133793..1136069 Lactococcus lactis subsp. lactis Il1403 1114760 NP_267277.1 CDS mutX NC_002662.1 1136089 1136556 D MutT; mutator protein 1136089..1136556 Lactococcus lactis subsp. lactis Il1403 1114761 NP_267278.1 CDS tag NC_002662.1 1136602 1137174 D hydrolysis of the deoxyribose N-glycosidc bond to excise 3-methyladenine from the damaged DNA polymer formed by alkylation lesions; DNA-3-methyladenine glycosidase I 1136602..1137174 Lactococcus lactis subsp. lactis Il1403 1114762 NP_267279.1 CDS yldC NC_002662.1 1137252 1137710 D hypothetical protein 1137252..1137710 Lactococcus lactis subsp. lactis Il1403 1114763 NP_267280.1 CDS frdC NC_002662.1 1137875 1139383 D Reduces fumarate to succinate in anaerobic bacterial respiration; fumarate reductase flavoprotein subunit 1137875..1139383 Lactococcus lactis subsp. lactis Il1403 1114764 NP_267281.1 CDS yldE NC_002662.1 1139554 1140246 D hypothetical protein 1139554..1140246 Lactococcus lactis subsp. lactis Il1403 1114765 NP_267282.1 CDS truB NC_002662.1 1140387 1141376 D catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 1140387..1141376 Lactococcus lactis subsp. lactis Il1403 1114766 NP_267283.1 CDS ribC NC_002662.1 1141407 1142309 D catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 1141407..1142309 Lactococcus lactis subsp. lactis Il1403 1114767 NP_267284.1 CDS ldhX NC_002662.1 1142407 1143378 D glycolysis; L-lactate dehydrogenase 1142407..1143378 Lactococcus lactis subsp. lactis Il1403 1114768 NP_267285.1 CDS yleB NC_002662.1 1143537 1144598 D surface protein; hypothetical protein 1143537..1144598 Lactococcus lactis subsp. lactis Il1403 1114769 NP_267286.1 CDS murQ NC_002662.1 1144591 1145484 D catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid 6-phosphate etherase 1144591..1145484 Lactococcus lactis subsp. lactis Il1403 1114770 NP_267287.1 CDS yleD NC_002662.1 1145519 1146883 D transport and binding protein; PTS system; PTS system sucrose-specific transporter subunit IIBC 1145519..1146883 Lactococcus lactis subsp. lactis Il1403 1114771 NP_267288.1 CDS yleE NC_002662.1 1146884 1147471 D transport and binding protein; PTS system; similar to beta-glucoside-specific PTS system IIABC component; hypothetical protein 1146884..1147471 Lactococcus lactis subsp. lactis Il1403 1114772 NP_267289.1 CDS yleF NC_002662.1 1147533 1148384 D RpiR family of transcription regulators; transcriptional regulator 1147533..1148384 Lactococcus lactis subsp. lactis Il1403 1114773 NP_267290.1 CDS tpiA NC_002662.1 1148515 1149273 D Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 1148515..1149273 Lactococcus lactis subsp. lactis Il1403 1114774 NP_267291.1 CDS pacA NC_002662.1 1149436 1150407 D drug and analog sensitivity; penicillin acylase 1149436..1150407 Lactococcus lactis subsp. lactis Il1403 1114775 NP_267292.1 CDS ylfA NC_002662.1 1150456 1151043 D hypothetical protein 1150456..1151043 Lactococcus lactis subsp. lactis Il1403 1114776 NP_267293.1 CDS ylfB NC_002662.1 1151258 1152595 D hypothetical protein 1151258..1152595 Lactococcus lactis subsp. lactis Il1403 1114777 NP_267294.1 CDS ylfC NC_002662.1 1152577 1153104 D hypothetical protein 1152577..1153104 Lactococcus lactis subsp. lactis Il1403 1114778 NP_267295.1 CDS hemN NC_002662.1 1153284 1154423 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 1153284..1154423 Lactococcus lactis subsp. lactis Il1403 1114779 NP_267296.1 CDS ylfD NC_002662.1 1154470 1155285 D hypothetical protein 1154470..1155285 Lactococcus lactis subsp. lactis Il1403 1114780 NP_267297.1 CDS dcdA NC_002662.1 1155388 1155831 D 2'-deoxyribonucleotide metabolism; dCMP deaminase 1155388..1155831 Lactococcus lactis subsp. lactis Il1403 1114781 NP_267299.1 CDS ylfH NC_002662.1 1156705 1157478 D amino sugars; N-acetylglucosamine catabolic protein 1156705..1157478 Lactococcus lactis subsp. lactis Il1403 1114784 NP_267300.1 CDS ylfI NC_002662.1 1157581 1158198 D hypothetical protein 1157581..1158198 Lactococcus lactis subsp. lactis Il1403 1114785 NP_267301.1 CDS guaC NC_002662.1 1158457 1159446 D purine ribonucleotide biosynthesis; similar also to inosine-5'-monophosphate dehydrogenases; maintains the intracellular balance of A and G nucleotides; guanosine 5'-monophosphate oxidoreductase 1158457..1159446 Lactococcus lactis subsp. lactis Il1403 1114786 NP_267302.1 CDS xpt NC_002662.1 1159718 1160311 D Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine; xanthine phosphoribosyltransferase 1159718..1160311 Lactococcus lactis subsp. lactis Il1403 1114787 NP_267303.1 CDS pbuX NC_002662.1 1160360 1161664 D transport and binding protein; nucleosides, purines and pyrimidines; xanthine/uracil permease 1160360..1161664 Lactococcus lactis subsp. lactis Il1403 1114788 NP_267304.1 CDS ylgB NC_002662.1 1161693 1162106 R hypothetical protein complement(1161693..1162106) Lactococcus lactis subsp. lactis Il1403 1114789 NP_267305.1 CDS ylgC NC_002662.1 1162226 1162735 R hypothetical protein complement(1162226..1162735) Lactococcus lactis subsp. lactis Il1403 1114790 NP_267306.1 CDS dfrA NC_002662.1 1163134 1163640 D evidence experimental PMID:7574597; folic acid; dihydropholate reductase 1163134..1163640 Lactococcus lactis subsp. lactis Il1403 1114791 NP_835313.1 CDS L200043 NC_002662.1 1163637 1163807 D hypothetical protein 1163637..1163807 Lactococcus lactis subsp. lactis Il1403 1114792 NP_267307.1 CDS clpX NC_002662.1 1163884 1165119 D binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 1163884..1165119 Lactococcus lactis subsp. lactis Il1403 1114793 NP_267308.1 CDS engB NC_002662.1 1165116 1165703 D binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 1165116..1165703 Lactococcus lactis subsp. lactis Il1403 1114794 NP_267309.1 CDS folB NC_002662.1 1165757 1166107 D folic acid; dihydroneopterin aldolase 1165757..1166107 Lactococcus lactis subsp. lactis Il1403 1114795 NP_267310.1 CDS folE NC_002662.1 1166187 1167236 D GTP-CH-I; folic acid; GTP cyclohydrolase I 1166187..1167236 Lactococcus lactis subsp. lactis Il1403 1114796 NP_267311.1 CDS folP NC_002662.1 1167233 1168306 D folic acid; dihydropteroate synthase 1167233..1168306 Lactococcus lactis subsp. lactis Il1403 1114797 NP_267312.1 CDS ylgG NC_002662.1 1168309 1168806 D hypothetical protein 1168309..1168806 Lactococcus lactis subsp. lactis Il1403 1114798 NP_267313.1 CDS folC NC_002662.1 1168825 1170108 D folic aci; folylpolyglutamate synthase 1168825..1170108 Lactococcus lactis subsp. lactis Il1403 1114799 NP_267314.1 CDS dukB NC_002662.1 1170238 1170876 D nucleotide and nucleoside interconversions; heterodimer of a deoxyadenosine and a deoxyguanosine kinase; deoxynucleoside kinase 1170238..1170876 Lactococcus lactis subsp. lactis Il1403 1114800 NP_267315.1 CDS hom NC_002662.1 1171053 1172339 D catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 1171053..1172339 Lactococcus lactis subsp. lactis Il1403 1114801 NP_267316.1 CDS thrB NC_002662.1 1172344 1173234 D catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 1172344..1173234 Lactococcus lactis subsp. lactis Il1403 1114802 NP_267317.1 CDS ylhB NC_002662.1 1173488 1174087 D hypothetical protein 1173488..1174087 Lactococcus lactis subsp. lactis Il1403 1114803 NP_267318.1 CDS murB NC_002662.1 1174130 1175029 D catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 1174130..1175029 Lactococcus lactis subsp. lactis Il1403 1114804 NP_267319.1 CDS potA NC_002662.1 1175681 1176967 D transport and binding protein; amino acids, peptides and amines; spermidine/putrescine ABC transporter ATP-binding protein 1175681..1176967 Lactococcus lactis subsp. lactis Il1403 1114805 NP_267320.1 CDS potB NC_002662.1 1176964 1177752 D transport and binding protein; amino acids, peptides and amines; spermidine/putrescine ABC transporter permease 1176964..1177752 Lactococcus lactis subsp. lactis Il1403 1114806 NP_267321.1 CDS potC NC_002662.1 1177754 1178554 D transport and binding protein; amino acids, peptides and amines; spermidine/putrescine ABC transporter permease 1177754..1178554 Lactococcus lactis subsp. lactis Il1403 1114807 NP_267322.1 CDS potD NC_002662.1 1178602 1179669 D transport and binding protein; amino acids, peptides and amines; spermidine/putrescine ABC transporter substrate binding protein 1178602..1179669 Lactococcus lactis subsp. lactis Il1403 1114808 NP_267323.1 CDS yliA NC_002662.1 1180044 1180904 D general regulatory function; positive transcription regulator 1180044..1180904 Lactococcus lactis subsp. lactis Il1403 1114809 NP_267324.1 CDS yliB NC_002662.1 1181003 1183261 D probably Fe-S oxidoreductase, evidenced by COGnitor; hypothetical protein 1181003..1183261 Lactococcus lactis subsp. lactis Il1403 1114810 NP_267327.1 CDS yliE NC_002662.1 1184767 1185156 D hypothetical protein 1184767..1185156 Lactococcus lactis subsp. lactis Il1403 1114813 NP_267328.1 CDS yliF NC_002662.1 1185119 1185682 D hypothetical protein 1185119..1185682 Lactococcus lactis subsp. lactis Il1403 1114814 NP_267329.1 CDS yliG NC_002662.1 1186321 1186668 D hypothetical protein 1186321..1186668 Lactococcus lactis subsp. lactis Il1403 1114815 NP_267330.1 CDS clsB NC_002662.1 1187132 1188595 D membranes, lipoproteins, and porinsl affects resistance to gyrace inhibitor novobiocin; condensation of two molecules of phosphattidylglycerol; cardiolipin synthase 1187132..1188595 Lactococcus lactis subsp. lactis Il1403 1114816 NP_267331.1 CDS yljB NC_002662.1 1191722 1192318 R Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase complement(1191722..1192318) Lactococcus lactis subsp. lactis Il1403 1114818 NP_267332.1 CDS yljC NC_002662.1 1192577 1193398 D RpiR family of transcription regulators; transcriptional regulator 1192577..1193398 Lactococcus lactis subsp. lactis Il1403 1114819 NP_267333.1 CDS yljD NC_002662.1 1193685 1193930 D hypothetical protein 1193685..1193930 Lactococcus lactis subsp. lactis Il1403 1114820 NP_267334.1 CDS yljE NC_002662.1 1194125 1195507 D probably a SAM-dependent RNA methyltransferase, evidenced by COGnitor; hypothetical protein 1194125..1195507 Lactococcus lactis subsp. lactis Il1403 1114821 NP_267335.1 CDS yljF NC_002662.1 1195544 1197151 D hypothetical protein 1195544..1197151 Lactococcus lactis subsp. lactis Il1403 1114822 NP_267336.1 CDS yljG NC_002662.1 1197153 1197773 D probably a methylase, involved in menaquinone biosynthesis, evidenced by COGnitor; hypothetical protein 1197153..1197773 Lactococcus lactis subsp. lactis Il1403 1114823 NP_267337.1 CDS yljH NC_002662.1 1197839 1198045 D hypothetical protein 1197839..1198045 Lactococcus lactis subsp. lactis Il1403 1114824 NP_267338.1 CDS yljI NC_002662.1 1198070 1199011 D transport and binding protein; permease 1198070..1199011 Lactococcus lactis subsp. lactis Il1403 1114825 NP_267339.1 CDS yljJ NC_002662.1 1199039 1200295 D hypothetical protein 1199039..1200295 Lactococcus lactis subsp. lactis Il1403 1114826 NP_267340.1 CDS als NC_002662.1 1200450 1202114 D catalyzes the formation of 2-acetolactate from pyruvate in stationary phase; acetolactate synthase 1200450..1202114 Lactococcus lactis subsp. lactis Il1403 1114827 NP_267341.1 CDS ymaB NC_002662.1 1202315 1202488 R hypothetical protein complement(1202315..1202488) Lactococcus lactis subsp. lactis Il1403 1114828 NP_267342.1 CDS mae NC_002662.1 1203477 1204619 D fermentation; malate oxidoreductase 1203477..1204619 Lactococcus lactis subsp. lactis Il1403 1114829 NP_267343.1 CDS citR NC_002662.1 1205754 1206683 R DeoR-family regulators; citrate lyase regulator complement(1205754..1206683) Lactococcus lactis subsp. lactis Il1403 1114831 NP_267344.1 CDS citC NC_002662.1 1206765 1207805 D TCA cycle; acetate-SH-citrate lyase ligase 1206765..1207805 Lactococcus lactis subsp. lactis Il1403 1114832 NP_267345.1 CDS citD NC_002662.1 1207795 1208085 D acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma 1207795..1208085 Lactococcus lactis subsp. lactis Il1403 1114833 NP_267346.1 CDS citE NC_002662.1 1208087 1209001 D TCA cycle; citrate lyase subunit beta 1208087..1209001 Lactococcus lactis subsp. lactis Il1403 1114834 NP_267347.1 CDS citF NC_002662.1 1208991 1210529 D TCA cycle; citrate lyase subunit alpha 1208991..1210529 Lactococcus lactis subsp. lactis Il1403 1114835 YP_008998702.1 CDS L0042a NC_002662.1 1210526 1211104 D apo-citrate lyase 1210526..1211104 Lactococcus lactis subsp. lactis Il1403 18245216 YP_008998703.1 CDS L0042b NC_002662.1 1211094 1211918 D triphosphoribosyl-dephospho-CoA synthase 1211094..1211918 Lactococcus lactis subsp. lactis Il1403 18245225 NP_267348.1 CDS ymbC NC_002662.1 1213089 1213409 D hypothetical protein 1213089..1213409 Lactococcus lactis subsp. lactis Il1403 1114838 NP_267349.1 CDS ymbD NC_002662.1 1213381 1213527 D hypothetical protein 1213381..1213527 Lactococcus lactis subsp. lactis Il1403 1114839 NP_835314.1 CDS ymbH NC_002662.1 1215335 1216084 D similar to protease; hypothetical protein 1215335..1216084 Lactococcus lactis subsp. lactis Il1403 1114840 NP_267351.1 CDS tra981E NC_002662.1 1216209 1217048 R evidence experimental PMID:8389385; transposon related function; related to a family of IS elements that includes IS2, IS3, IS150, IS600, IS629, IS861, IS904 and ISL1; transposase of IS981E complement(1216209..1217048) Lactococcus lactis subsp. lactis Il1403 1114841 NP_267352.1 CDS ymbI NC_002662.1 1217060 1217320 R transposon related function; orf1 of IS981; transposase complement(1217060..1217320) Lactococcus lactis subsp. lactis Il1403 1114842 NP_267353.1 CDS ymbJ NC_002662.1 1217351 1219600 D hypothetical protein 1217351..1219600 Lactococcus lactis subsp. lactis Il1403 1114843 NP_267354.1 CDS ymbK NC_002662.1 1219654 1219971 D hypothetical protein 1219654..1219971 Lactococcus lactis subsp. lactis Il1403 1114844 NP_267355.1 CDS ymcA NC_002662.1 1219968 1220498 D hypothetical protein 1219968..1220498 Lactococcus lactis subsp. lactis Il1403 1114845 NP_267356.1 CDS ymcB NC_002662.1 1220495 1221142 D hypothetical protein 1220495..1221142 Lactococcus lactis subsp. lactis Il1403 1114846 NP_267357.1 CDS ymcC NC_002662.1 1221037 1221600 D hypothetical protein 1221037..1221600 Lactococcus lactis subsp. lactis Il1403 1114847 NP_267358.1 CDS ymcD NC_002662.1 1221637 1221897 D transposon related function; orf1 of IS981; transposase 1221637..1221897 Lactococcus lactis subsp. lactis Il1403 1114848 NP_835315.1 CDS ymcE NC_002662.1 1223001 1223219 D similar to EpsR of the epsRXABCDEFGHIJKL operon of Lactococcus lactis plasmid pNZ4000; hypothetical protein 1223001..1223219 Lactococcus lactis subsp. lactis Il1403 1114849 NP_267359.1 CDS ymcF NC_002662.1 1223254 1224270 D hypothetical protein 1223254..1224270 Lactococcus lactis subsp. lactis Il1403 1114850 NP_267360.1 CDS tra905 NC_002662.1 1224836 1226011 D evidence experimental PMID:8195098; transposon related function; transposase of IS905 1224836..1226011 Lactococcus lactis subsp. lactis Il1403 1114851 NP_267361.1 CDS vacB2 NC_002662.1 1226204 1228201 D degradation of RNA; ribonuclease II (RNB) family; ribonuclease 1226204..1228201 Lactococcus lactis subsp. lactis Il1403 1114852 NP_267362.1 CDS hisC NC_002662.1 1228672 1229754 D catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 1228672..1229754 Lactococcus lactis subsp. lactis Il1403 1114853 NP_267363.1 CDS hisZ NC_002662.1 1229867 1230727 D ATP phosphoribosyltransferase regulatory subunit 1229867..1230727 Lactococcus lactis subsp. lactis Il1403 1114854 NP_267364.1 CDS hisG NC_002662.1 1230720 1231262 D short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ; ATP phosphoribosyltransferase catalytic subunit 1230720..1231262 Lactococcus lactis subsp. lactis Il1403 1114855 NP_267365.1 CDS hisD NC_002662.1 1231329 1232624 D evidence experimental PMID:1400209; histidine family; histidinol dehydrogenase 1231329..1232624 Lactococcus lactis subsp. lactis Il1403 1114856 NP_267366.1 CDS hisB NC_002662.1 1233461 1234063 D catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; imidazoleglycerol-phosphate dehydratase 1233461..1234063 Lactococcus lactis subsp. lactis Il1403 1114858 NP_267367.1 CDS ymdC NC_002662.1 1234060 1234848 D drug and analog sensitivity; kanamycin kinase 1234060..1234848 Lactococcus lactis subsp. lactis Il1403 1114859 NP_267368.1 CDS hisH NC_002662.1 1234887 1235495 D with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 1234887..1235495 Lactococcus lactis subsp. lactis Il1403 1114860 NP_267369.1 CDS hisA NC_002662.1 1235496 1236215 D catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 1235496..1236215 Lactococcus lactis subsp. lactis Il1403 1114861 NP_267370.1 CDS hisF NC_002662.1 1236205 1236984 D catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 1236205..1236984 Lactococcus lactis subsp. lactis Il1403 1114862 NP_267371.1 CDS hisI NC_002662.1 1236981 1237619 D catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase 1236981..1237619 Lactococcus lactis subsp. lactis Il1403 1114863 NP_267372.1 CDS hisK NC_002662.1 1237620 1238429 D histidine family; histidinol phosphatase 1237620..1238429 Lactococcus lactis subsp. lactis Il1403 1114864 NP_267373.1 CDS ymdE NC_002662.1 1238443 1239402 R hypothetical protein complement(1238443..1239402) Lactococcus lactis subsp. lactis Il1403 1114865 NP_267374.1 CDS leuB NC_002662.1 1241356 1242318 D catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 1241356..1242318 Lactococcus lactis subsp. lactis Il1403 1114867 NP_267375.1 CDS ymeA NC_002662.1 1242353 1242775 R hypothetical protein complement(1242353..1242775) Lactococcus lactis subsp. lactis Il1403 1114868 NP_267376.1 CDS leuC NC_002662.1 1242879 1244261 D dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 1242879..1244261 Lactococcus lactis subsp. lactis Il1403 1114869 NP_267377.1 CDS leuD NC_002662.1 1244281 1244856 D catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 1244281..1244856 Lactococcus lactis subsp. lactis Il1403 1114870 NP_267378.2 CDS ymeB NC_002662.1 1244870 1245649 D transport and binding protein; branched chain amino acid biosynthesis operon; ABC transporter ATP-binding protein 1244870..1245649 Lactococcus lactis subsp. lactis Il1403 1114871 NP_267379.1 CDS ilvD NC_002662.1 1245771 1247483 D catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 1245771..1247483 Lactococcus lactis subsp. lactis Il1403 1114872 NP_267380.1 CDS ilvB NC_002662.1 1247599 1249221 D catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase catalytic subunit 1247599..1249221 Lactococcus lactis subsp. lactis Il1403 1114873 NP_267381.1 CDS ilvH NC_002662.1 1249214 1249690 D with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 1249214..1249690 Lactococcus lactis subsp. lactis Il1403 1114874 NP_267382.1 CDS ilvC NC_002662.1 1249736 1250758 D catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 1249736..1250758 Lactococcus lactis subsp. lactis Il1403 1114875 NP_267383.1 CDS ilvA NC_002662.1 1250814 1252064 D catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic; threonine dehydratase 1250814..1252064 Lactococcus lactis subsp. lactis Il1403 1114876 NP_267384.1 CDS aldB NC_002662.1 1252180 1252890 D evidence experimental PMID:8779600; fermentation; converts acetolactate into acetoin;may be a mechanism for controlling the internal pH of cells in stationary phase; alpha-acetolactate decarboxylase 1252180..1252890 Lactococcus lactis subsp. lactis Il1403 1114877 NP_267385.1 CDS aldR NC_002662.1 1252931 1253311 D regulatory protein; general regulatory function; AldR 1252931..1253311 Lactococcus lactis subsp. lactis Il1403 1114878 NP_267386.1 CDS topA NC_002662.1 1254565 1256697 D catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1254565..1256697 Lactococcus lactis subsp. lactis Il1403 1114880 NP_267387.1 CDS gidC NC_002662.1 1256769 1258112 D TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; tRNA (uracil-5-)-methyltransferase Gid 1256769..1258112 Lactococcus lactis subsp. lactis Il1403 1114881 NP_267388.1 CDS xerS NC_002662.1 1258157 1259227 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerS; site-specific tyrosine recombinase XerS complement(1258157..1259227) Lactococcus lactis subsp. lactis Il1403 1114882 NP_267391.1 CDS ymgC NC_002662.1 1261619 1263337 D hypothetical protein 1261619..1263337 Lactococcus lactis subsp. lactis Il1403 1114884 NP_267392.1 CDS rlrA NC_002662.1 1263405 1264316 D LysR-family regulator; LysR family transcriptional regulator 1263405..1264316 Lactococcus lactis subsp. lactis Il1403 1114885 NP_267393.1 CDS ceo NC_002662.1 1264586 1265515 R evidence experimental PMID:7744873; aspartate family; component of sucrose-nisin transposon Tn5306; N5-carboxyethyl-ornithine synthase complement(1264586..1265515) Lactococcus lactis subsp. lactis Il1403 1114886 NP_267394.1 CDS ymgF NC_002662.1 1265554 1265733 R similar to C-part of 37 kD protein from sucrose-nisin transposon Tn5306; hypothetical protein complement(1265554..1265733) Lactococcus lactis subsp. lactis Il1403 1114887 NP_267395.1 CDS ymgG NC_002662.1 1265891 1266442 R similar to a 20 kD protein from sucrose-nisin transposon Tn5306; hypothetical protein complement(1265891..1266442) Lactococcus lactis subsp. lactis Il1403 1114888 NP_267396.1 CDS ymgH NC_002662.1 1266463 1266651 R similar to a 6-kDa protein from sucrose-nisin transposon Tn5306; hypothetical protein complement(1266463..1266651) Lactococcus lactis subsp. lactis Il1403 1114889 NP_267397.1 CDS ymgI NC_002662.1 1266661 1267221 R hypothetical protein complement(1266661..1267221) Lactococcus lactis subsp. lactis Il1403 1114890 NP_267398.1 CDS ymgJ NC_002662.1 1267256 1267498 R similar to YdaS of Bacillus subtilis; hypothetical protein complement(1267256..1267498) Lactococcus lactis subsp. lactis Il1403 1114891 NP_267399.1 CDS ymgK NC_002662.1 1267992 1268834 D aerobic energy metabolism; oxidoreductase 1267992..1268834 Lactococcus lactis subsp. lactis Il1403 1114892 NP_267400.1 CDS glpF2 NC_002662.1 1269307 1270044 R transport and binding protein, carbohydrates; organic alcohols and acids; glycerol utilization pathway; glycerol uptake facilitator complement(1269307..1270044) Lactococcus lactis subsp. lactis Il1403 1114893 NP_267401.1 CDS glpD NC_002662.1 1270095 1271924 R anaerobic energy metabolism; glycerol utilization pathway; glycerol-3-phosphate dehydrogenase complement(1270095..1271924) Lactococcus lactis subsp. lactis Il1403 1114894 NP_267402.1 CDS glpK NC_002662.1 1271961 1273457 R Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase complement(1271961..1273457) Lactococcus lactis subsp. lactis Il1403 1114895 NP_267403.1 CDS ymhA NC_002662.1 1273826 1275292 R hypothetical protein complement(1273826..1275292) Lactococcus lactis subsp. lactis Il1403 1114896 NP_267404.1 CDS tra981G NC_002662.1 1275416 1276255 R evidence experimental PMID:8389385; transposon related function; related to a family of IS elements that includes IS2, IS3, IS150, IS600, IS629, IS861, IS904 and ISL1; transposase of IS981G complement(1275416..1276255) Lactococcus lactis subsp. lactis Il1403 1114897 NP_267405.1 CDS ymhB NC_002662.1 1276267 1276527 R transposon related function; orf1 of IS981; transposase complement(1276267..1276527) Lactococcus lactis subsp. lactis Il1403 1114898 NP_267406.1 CDS ymhC NC_002662.1 1276583 1277206 R hypothetical protein complement(1276583..1277206) Lactococcus lactis subsp. lactis Il1403 1114899 NP_267407.1 CDS amyL NC_002662.1 1277443 1278918 D converts 1,4-alpha-D-glucans to maltodextrin; alpha-amylase 1277443..1278918 Lactococcus lactis subsp. lactis Il1403 1114900 NP_267408.1 CDS lctO NC_002662.1 1278985 1280136 R anaerobic energy metabolism; L-lactate utilization gene; L-lactate oxidase complement(1278985..1280136) Lactococcus lactis subsp. lactis Il1403 1114901 NP_267409.1 CDS aroH NC_002662.1 1280370 1281392 R catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase complement(1280370..1281392) Lactococcus lactis subsp. lactis Il1403 1114902 NP_267410.1 CDS metF NC_002662.1 1281756 1282607 R aspartate family; 5,10-methylenetetrahydrofolate reductase complement(1281756..1282607) Lactococcus lactis subsp. lactis Il1403 1114903 NP_267411.2 CDS metE NC_002662.1 1282597 1284870 R catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase complement(1282597..1284870) Lactococcus lactis subsp. lactis Il1403 1114904 NP_267412.1 CDS ymiA NC_002662.1 1285022 1285675 R general regulatory function; metalloregulator complement(1285022..1285675) Lactococcus lactis subsp. lactis Il1403 1114905 NP_267413.1 CDS mgtA NC_002662.1 1285769 1288501 R transort and binding protein, cations; cation-transporting P-ATPase complement(1285769..1288501) Lactococcus lactis subsp. lactis Il1403 1114906 NP_267414.1 CDS dltD NC_002662.1 1288984 1290270 R D-alanine transfer protein complement(1288984..1290270) Lactococcus lactis subsp. lactis Il1403 1114907 NP_267415.1 CDS dltC NC_002662.1 1290260 1290499 R D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 2 complement(1290260..1290499) Lactococcus lactis subsp. lactis Il1403 1114908 NP_267416.1 CDS dltB NC_002662.1 1290542 1291765 R surface polysaccharides, lipopolysaccharides and antigens; may be involved in transport of activated D-alanine through the membrane; peptidoglycan biosynthesis protein complement(1290542..1291765) Lactococcus lactis subsp. lactis Il1403 1114909 NP_267417.1 CDS dltA NC_002662.1 1291765 1293264 R transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 1 complement(1291765..1293264) Lactococcus lactis subsp. lactis Il1403 1114910 NP_267418.1 CDS thiE NC_002662.1 1293610 1294257 R thiamin-phosphate pyrophosphorylase complement(1293610..1294257) Lactococcus lactis subsp. lactis Il1403 1114911 NP_267419.1 CDS thiD1 NC_002662.1 1294247 1295050 R thiamine; also functions in a salvage pathway; phosphomethylpyrimidine kinase complement(1294247..1295050) Lactococcus lactis subsp. lactis Il1403 1114912 NP_267420.1 CDS thiM NC_002662.1 1295064 1295816 R catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase complement(1295064..1295816) Lactococcus lactis subsp. lactis Il1403 1114913 NP_267421.1 CDS ymjE NC_002662.1 1296101 1298575 R surface polysaccharides, lipopolysaccharides and antigens; glycosyltransferase, probably involved in cell wall biogenesis, evidenced by COGnitor; glycosyl transferase family protein complement(1296101..1298575) Lactococcus lactis subsp. lactis Il1403 1114914 NP_267422.1 CDS ymjF NC_002662.1 1298565 1299653 R surface polysaccharides, lipopolysaccharides and antigens; UDP-N-acetylglucosamine 2-epimerase complement(1298565..1299653) Lactococcus lactis subsp. lactis Il1403 1114915 NP_267424.1 CDS rplL NC_002662.1 1300979 1301344 R present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 complement(1300979..1301344) Lactococcus lactis subsp. lactis Il1403 1114917 NP_267425.1 CDS rplJ NC_002662.1 1301414 1301929 R binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 complement(1301414..1301929) Lactococcus lactis subsp. lactis Il1403 1114918 NP_267426.1 CDS ynaA NC_002662.1 1302151 1302339 R hypothetical protein complement(1302151..1302339) Lactococcus lactis subsp. lactis Il1403 1114919 NP_267427.1 CDS ynaB NC_002662.1 1302355 1303113 R general regulatory function; transcriptional regulator complement(1302355..1303113) Lactococcus lactis subsp. lactis Il1403 1114920 NP_267428.1 CDS ynaC NC_002662.1 1303234 1305060 R transport and binding protein; ABC transporter ATP-binding protein/permease complement(1303234..1305060) Lactococcus lactis subsp. lactis Il1403 1114921 NP_267429.1 CDS ynaD NC_002662.1 1305044 1306861 R transport and binding protein; ABC transporter ATP-binding protein/permease complement(1305044..1306861) Lactococcus lactis subsp. lactis Il1403 1114922 NP_267430.2 CDS ynaE NC_002662.1 1307010 1307630 R hypothetical protein complement(1307010..1307630) Lactococcus lactis subsp. lactis Il1403 1114923 NP_267431.2 CDS rluB NC_002662.1 1307979 1308698 R RNA synthesis, modification, and DNA transcription; synthesis of pseudouridine from uracil-2650 in 23S ribosomal RNA; family 1 of pseudouridine synthases; pseudouridine synthase complement(1307979..1308698) Lactococcus lactis subsp. lactis Il1403 1114924 NP_267432.2 CDS scpB NC_002662.1 1308685 1309251 R functions during chromosome segregation; may form a condensin-like structure with SMC and ScpA; forms a homodimer; segregation and condensation protein B complement(1308685..1309251) Lactococcus lactis subsp. lactis Il1403 1114925 NP_267433.1 CDS scpA NC_002662.1 1309244 1309972 R functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB; segregation and condensation protein A complement(1309244..1309972) Lactococcus lactis subsp. lactis Il1403 1114926 NP_267434.2 CDS xerD NC_002662.1 1310002 1310718 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD complement(1310002..1310718) Lactococcus lactis subsp. lactis Il1403 1114927 NP_267435.1 CDS ynbB NC_002662.1 1310696 1311157 R hypothetical protein complement(1310696..1311157) Lactococcus lactis subsp. lactis Il1403 1114928 NP_267436.1 CDS ynbC NC_002662.1 1311188 1311691 R hypothetical protein complement(1311188..1311691) Lactococcus lactis subsp. lactis Il1403 1114929 NP_267439.1 CDS ynbE NC_002662.1 1313315 1313554 R hypothetical protein complement(1313315..1313554) Lactococcus lactis subsp. lactis Il1403 1114932 NP_267440.1 CDS lysA NC_002662.1 1313706 1314965 R aspartate family; diaminopimelate decarboxylase complement(1313706..1314965) Lactococcus lactis subsp. lactis Il1403 1114933 NP_267441.1 CDS gltD NC_002662.1 1315082 1316521 R glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta complement(1315082..1316521) Lactococcus lactis subsp. lactis Il1403 1114934 NP_267442.1 CDS gltB NC_002662.1 1316521 1320981 R glutamate family; nitrogen metabolism; brings together nitrogen and carbon metabolism; glutamate synthase large subunit complement(1316521..1320981) Lactococcus lactis subsp. lactis Il1403 1114935 NP_267443.1 CDS yncA NC_002662.1 1321150 1321761 D sugars; acetyltransferase 1321150..1321761 Lactococcus lactis subsp. lactis Il1403 1114936 NP_267444.1 CDS bcaT NC_002662.1 1321794 1322816 R catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase complement(1321794..1322816) Lactococcus lactis subsp. lactis Il1403 1114937 NP_267445.1 CDS yncB NC_002662.1 1322977 1323723 D integral membrane protein; hypothetical protein 1322977..1323723 Lactococcus lactis subsp. lactis Il1403 1114938 NP_267446.1 CDS gadB NC_002662.1 1323836 1325236 R evidence experimental PMID:9484886; energy metabolism, amino acids and amines; glutamate decarboxylase complement(1323836..1325236) Lactococcus lactis subsp. lactis Il1403 1114939 NP_267447.1 CDS gadC NC_002662.1 1325256 1326767 R evidence experimental PMID:9484886; transport and binding protein; amino acids, peptides and amines; glutamate-gamma-aminobutyrate complement(1325256..1326767) Lactococcus lactis subsp. lactis Il1403 1114940 NP_267448.1 CDS gadR NC_002662.1 1326911 1327741 R evidence experimental PMID:9484886; activates chloride dependent transcription of gadCB ,homologous to the activator Rgg from Streptococcus gordonii.; positive regulator complement(1326911..1327741) Lactococcus lactis subsp. lactis Il1403 1114941 NP_267449.1 CDS rnhB NC_002662.1 1328294 1329070 R RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII complement(1328294..1329070) Lactococcus lactis subsp. lactis Il1403 1114942 NP_267450.1 CDS rbgA NC_002662.1 1329206 1330054 R essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc); ribosomal biogenesis GTPase complement(1329206..1330054) Lactococcus lactis subsp. lactis Il1403 1114943 NP_267451.1 CDS yndA NC_002662.1 1330278 1330823 R hypothetical protein complement(1330278..1330823) Lactococcus lactis subsp. lactis Il1403 1114944 NP_267452.1 CDS yndB NC_002662.1 1330915 1331664 R hypothetical protein complement(1330915..1331664) Lactococcus lactis subsp. lactis Il1403 1114945 NP_267453.1 CDS rdrB NC_002662.1 1331842 1332603 D DeoR-family regulator; transcriptional regulator 1331842..1332603 Lactococcus lactis subsp. lactis Il1403 1114946 NP_267456.1 CDS yndE NC_002662.1 1334047 1334574 R hypothetical protein complement(1334047..1334574) Lactococcus lactis subsp. lactis Il1403 1114949 NP_267457.1 CDS yndF NC_002662.1 1334649 1336610 R similar to internalin of Listeria monocytogenes; membrane protein; hypothetical protein complement(1334649..1336610) Lactococcus lactis subsp. lactis Il1403 1114950 NP_267458.1 CDS yndG NC_002662.1 1336910 1337914 R transort and binding protein, cations; metal ABC transporter substrate binding protein complement(1336910..1337914) Lactococcus lactis subsp. lactis Il1403 1114951 NP_267459.1 CDS tra983D NC_002662.1 1337988 1338935 D transposon related function; belongs to the IS30 family of transposase; transposase of IS983D 1337988..1338935 Lactococcus lactis subsp. lactis Il1403 1114952 NP_267460.1 CDS ipd NC_002662.1 1338895 1340268 R energy metabolism, amino acids and amines; indole-3-pyruvate decarboxylase complement(1338895..1340268) Lactococcus lactis subsp. lactis Il1403 1114953 NP_267461.1 CDS rmaF NC_002662.1 1340403 1340873 D MarR-family regulator; transcriptional regulator 1340403..1340873 Lactococcus lactis subsp. lactis Il1403 1114954 NP_267462.1 CDS rlrC NC_002662.1 1340924 1341745 D LysR-family regulator; LysR family transcriptional regulator 1340924..1341745 Lactococcus lactis subsp. lactis Il1403 1114955 NP_267463.1 CDS yneB NC_002662.1 1341786 1342559 R hypothetical protein complement(1341786..1342559) Lactococcus lactis subsp. lactis Il1403 1114956 NP_267464.1 CDS yneC NC_002662.1 1342666 1342863 R hypothetical protein complement(1342666..1342863) Lactococcus lactis subsp. lactis Il1403 1114957 NP_267465.1 CDS yneD NC_002662.1 1343087 1343899 D aerobic energy metabolism; short chain dehydrogenase 1343087..1343899 Lactococcus lactis subsp. lactis Il1403 1114958 NP_267466.1 CDS yneE NC_002662.1 1343916 1344890 D AraC-family regulator; similar to OruR of Pseudomonas aeruginosa.; transcriptional regulator 1343916..1344890 Lactococcus lactis subsp. lactis Il1403 1114959 NP_267467.1 CDS yneF NC_002662.1 1345039 1345575 D hypothetical protein 1345039..1345575 Lactococcus lactis subsp. lactis Il1403 1114960 NP_267468.1 CDS yneG NC_002662.1 1345631 1345954 R hypothetical protein complement(1345631..1345954) Lactococcus lactis subsp. lactis Il1403 1114961 NP_267469.2 CDS yneH NC_002662.1 1346013 1346384 R hypothetical protein complement(1346013..1346384) Lactococcus lactis subsp. lactis Il1403 1114962 NP_267470.1 CDS pabB NC_002662.1 1346573 1348459 R folic acid; folate biosynthesis pathway; para-aminobenzoate synthase component I complement(1346573..1348459) Lactococcus lactis subsp. lactis Il1403 1114963 NP_267471.1 CDS pabA NC_002662.1 1348464 1349045 R folic acid; folate biosynthesis pathway; para-aminobenzoate synthase component II complement(1348464..1349045) Lactococcus lactis subsp. lactis Il1403 1114964 NP_267472.1 CDS mtsA NC_002662.1 1349213 1350154 R transport and binding protein, cations; belongs to streptococcal LraI protein family, involved on adherence to extracellular matrix, important factor in the pathogenesis and infection; manganese ABC transporter substrate binding protein complement(1349213..1350154) Lactococcus lactis subsp. lactis Il1403 1114965 NP_267473.1 CDS mtsC NC_002662.1 1350147 1350992 R transort and binding protein, cations; manganese ABC transporter permease complement(1350147..1350992) Lactococcus lactis subsp. lactis Il1403 1114966 NP_267474.1 CDS mtsB NC_002662.1 1351000 1351713 R transort and binding protein, cations; manganese ABC transporter ATP binding protein complement(1351000..1351713) Lactococcus lactis subsp. lactis Il1403 1114967 NP_267475.1 CDS ynfC NC_002662.1 1351988 1352401 D hypothetical protein 1351988..1352401 Lactococcus lactis subsp. lactis Il1403 1114968 NP_267476.1 CDS ynfD NC_002662.1 1352482 1352715 R hypothetical protein complement(1352482..1352715) Lactococcus lactis subsp. lactis Il1403 1114969 NP_267477.1 CDS sbcC NC_002662.1 1352843 1355983 R degradation of DNA; affects genetic recombination and the variability of DNA palindromes; may have nuclease activity related to RecBCD; ATP-dependent dsDNA exonuclease complement(1352843..1355983) Lactococcus lactis subsp. lactis Il1403 1114970 NP_267478.1 CDS sbcD NC_002662.1 1355986 1357158 R degradation of DNA; probably involved in genetic recombination; exonuclease complement(1355986..1357158) Lactococcus lactis subsp. lactis Il1403 1114971 NP_267479.1 CDS panE NC_002662.1 1357310 1358248 R ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase complement(1357310..1358248) Lactococcus lactis subsp. lactis Il1403 1114972 NP_267480.1 CDS ynfG NC_002662.1 1358448 1358867 R hypothetical protein complement(1358448..1358867) Lactococcus lactis subsp. lactis Il1403 1114973 NP_267481.1 CDS ynfH NC_002662.1 1359619 1361796 R hypothetical protein complement(1359619..1361796) Lactococcus lactis subsp. lactis Il1403 1114974 NP_267482.1 CDS yngA NC_002662.1 1362143 1362586 R hypothetical protein complement(1362143..1362586) Lactococcus lactis subsp. lactis Il1403 1114975 NP_267483.1 CDS yngB NC_002662.1 1362894 1364516 D transport and binding protein; similar to fibronectin-binding proteins of Streptococci; fibronectin-binding protein 1362894..1364516 Lactococcus lactis subsp. lactis Il1403 1114976 NP_267484.1 CDS yngE NC_002662.1 1365549 1367069 D transport and binding protein, carbohydrates; organic alcohols and acids; sugar ABC transporter ATP binding protein 1365549..1367069 Lactococcus lactis subsp. lactis Il1403 1114978 NP_267485.1 CDS yngF NC_002662.1 1367062 1368156 D transport and binding protein, carbohydrates; organic alcohols and acids; sugar ABC transporter permease 1367062..1368156 Lactococcus lactis subsp. lactis Il1403 1114979 NP_267486.1 CDS yngG NC_002662.1 1368153 1369106 D transport and binding protein, carbohydrates; organic alcohols and acids; sugar ABC transporter permease 1368153..1369106 Lactococcus lactis subsp. lactis Il1403 1114980 NP_267487.1 CDS ldh NC_002662.1 1369224 1370201 R Converts (S)-lactate and NAD(+) to pyruvate and NADH; L-lactate dehydrogenase complement(1369224..1370201) Lactococcus lactis subsp. lactis Il1403 1114981 NP_267488.1 CDS pyk NC_002662.1 1370319 1371827 R catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase complement(1370319..1371827) Lactococcus lactis subsp. lactis Il1403 1114982 NP_267489.1 CDS pfkA NC_002662.1 1371915 1372937 R catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase complement(1371915..1372937) Lactococcus lactis subsp. lactis Il1403 1114983 NP_267490.1 CDS ynhA NC_002662.1 1373039 1373314 R hypothetical protein complement(1373039..1373314) Lactococcus lactis subsp. lactis Il1403 1114984 NP_267491.1 CDS nagA NC_002662.1 1373323 1374471 R amino sugars; N-acetylglucosamine-6-phosphate deacetylase complement(1373323..1374471) Lactococcus lactis subsp. lactis Il1403 1114985 NP_267492.1 CDS ynhC NC_002662.1 1374644 1375822 R similar to YaaN of Bacillus subtilis; hypothetical protein complement(1374644..1375822) Lactococcus lactis subsp. lactis Il1403 1114986 NP_267493.1 CDS ynhD NC_002662.1 1375967 1376593 R similar to 5-bromo-4-chloroindolyl phosphate hydrolysis protein; hypothetical protein complement(1375967..1376593) Lactococcus lactis subsp. lactis Il1403 1114987 NP_267494.1 CDS gpsA NC_002662.1 1376785 1377810 D catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 1376785..1377810 Lactococcus lactis subsp. lactis Il1403 1114988 NP_267495.1 CDS hasC NC_002662.1 1377854 1378795 D surface polysaccharides, lipopolysaccharides and antigens; hyaluronate synthesis pathway; UTP-glucose-1-phosphate uridylyltransferase 1377854..1378795 Lactococcus lactis subsp. lactis Il1403 1114989 NP_267496.1 CDS ynhH NC_002662.1 1378866 1379273 D contains signal peptide; hypothetical protein 1378866..1379273 Lactococcus lactis subsp. lactis Il1403 1114990 NP_267497.1 CDS ynhI NC_002662.1 1379270 1379800 D hypothetical protein 1379270..1379800 Lactococcus lactis subsp. lactis Il1403 1114991 NP_267498.1 CDS ispB NC_002662.1 1379791 1380750 D heptaprenyl diphosphate synthase component II 1379791..1380750 Lactococcus lactis subsp. lactis Il1403 1114992 NP_267499.1 CDS gidB NC_002662.1 1380747 1381463 D glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 1380747..1381463 Lactococcus lactis subsp. lactis Il1403 1114993 NP_267500.1 CDS yniC NC_002662.1 1381693 1381944 R similar to cytochrome oxidase subunit III; hypothetical protein complement(1381693..1381944) Lactococcus lactis subsp. lactis Il1403 1114994 NP_267501.1 CDS pyrF NC_002662.1 1381946 1382659 R OMP decarboxylase; OMPDCase; OMPdecase; type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase complement(1381946..1382659) Lactococcus lactis subsp. lactis Il1403 1114995 NP_267502.1 CDS pydB NC_002662.1 1382809 1383744 R catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits, similar to the PyrDA subunits and two PyrK subunits; dihydroorotate dehydrogenase 1B complement(1382809..1383744) Lactococcus lactis subsp. lactis Il1403 1114996 NP_267503.1 CDS pyrZ NC_002662.1 1383817 1384605 R pyrimidine ribonucleotide biosynthesis; dihydroorotate dehydrogenase electron transfer subunit complement(1383817..1384605) Lactococcus lactis subsp. lactis Il1403 1114997 NP_267504.1 CDS yniG NC_002662.1 1385072 1386436 R transport and binding protein; multidrug resistance; similar to LmrB of Bacillus subtilis; drug-export protein complement(1385072..1386436) Lactococcus lactis subsp. lactis Il1403 1114998 NP_267505.2 CDS yniH NC_002662.1 1386813 1388024 D hypothetical protein 1386813..1388024 Lactococcus lactis subsp. lactis Il1403 1114999 NP_267506.1 CDS yniI NC_002662.1 1388184 1389323 D hypothetical protein 1388184..1389323 Lactococcus lactis subsp. lactis Il1403 1115000 NP_267507.1 CDS yniJ NC_002662.1 1389320 1390105 D hypothetical protein 1389320..1390105 Lactococcus lactis subsp. lactis Il1403 1115001 NP_267508.1 CDS rluC NC_002662.1 1390135 1390692 R pseudouridine synthase complement(1390135..1390692) Lactococcus lactis subsp. lactis Il1403 1115002 NP_267509.1 CDS ynjB NC_002662.1 1391010 1391336 R hypothetical protein complement(1391010..1391336) Lactococcus lactis subsp. lactis Il1403 1115003 NP_267510.1 CDS ynjC NC_002662.1 1391305 1392174 R hypothetical protein complement(1391305..1392174) Lactococcus lactis subsp. lactis Il1403 1115004 NP_267511.1 CDS ynjD NC_002662.1 1392252 1393064 R hypothetical protein complement(1392252..1393064) Lactococcus lactis subsp. lactis Il1403 1115005 NP_267512.1 CDS ynjE NC_002662.1 1393039 1393383 R hypothetical protein complement(1393039..1393383) Lactococcus lactis subsp. lactis Il1403 1115006 NP_267513.1 CDS ynjF NC_002662.1 1393430 1394434 R hypothetical protein complement(1393430..1394434) Lactococcus lactis subsp. lactis Il1403 1115007 NP_267514.1 CDS ynjG NC_002662.1 1394446 1395546 R hypothetical protein complement(1394446..1395546) Lactococcus lactis subsp. lactis Il1403 1115008 NP_267515.1 CDS tra983E NC_002662.1 1395697 1396644 D transposon related function; belongs to the IS30 family of transposase; transposase of IS983E 1395697..1396644 Lactococcus lactis subsp. lactis Il1403 1115009 NP_267516.1 CDS ynjH NC_002662.1 1396604 1397011 R hypothetical protein complement(1396604..1397011) Lactococcus lactis subsp. lactis Il1403 1115010 NP_267517.1 CDS ynjI NC_002662.1 1397062 1397496 R hypothetical protein complement(1397062..1397496) Lactococcus lactis subsp. lactis Il1403 1115011 NP_267518.1 CDS ynjJ NC_002662.1 1397509 1398090 R hypothetical protein complement(1397509..1398090) Lactococcus lactis subsp. lactis Il1403 1115012 NP_267519.1 CDS carB NC_002662.1 1398287 1401481 R four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit complement(1398287..1401481) Lactococcus lactis subsp. lactis Il1403 1115013 NP_267520.2 CDS gpo NC_002662.1 1401793 1402266 R thioredoxin, glutaredoxin, and glutathione; cellular metabolism or defense processes; glutathione peroxidase complement(1401793..1402266) Lactococcus lactis subsp. lactis Il1403 1115014 NP_267521.1 CDS acmC NC_002662.1 1402449 1403078 D cell envelope, murein sacculus and peptidoglycan; muramidase needed for cell separation and responsible for autolysis; similar to Orf39 of Bacillus subtilis bacteriophage phi-105; N-acetylmuramidase 1402449..1403078 Lactococcus lactis subsp. lactis Il1403 1115015 NP_267522.1 CDS yoaB NC_002662.1 1403120 1405756 R transort and binding protein, cations; cation-transporting ATPase complement(1403120..1405756) Lactococcus lactis subsp. lactis Il1403 1115016 NP_267523.1 CDS yoaD NC_002662.1 1406014 1406739 R hypothetical protein complement(1406014..1406739) Lactococcus lactis subsp. lactis Il1403 1115017 NP_267524.1 CDS yoaF NC_002662.1 1406957 1407526 R similar to a hydrophobic protein of Lactobacillus fermentum accession number U97348; hypothetical protein complement(1406957..1407526) Lactococcus lactis subsp. lactis Il1403 1115018 NP_267525.1 CDS yoaG NC_002662.1 1407667 1408482 R hypothetical protein complement(1407667..1408482) Lactococcus lactis subsp. lactis Il1403 1115019 NP_267526.1 CDS yoaH NC_002662.1 1408993 1409535 D similar to unknown protein MTH1490 of Methanobacterium thermoautotrophicum; hypothetical protein 1408993..1409535 Lactococcus lactis subsp. lactis Il1403 1115020 NP_267527.1 CDS yoaI NC_002662.1 1409731 1410489 D similar to hypothetical membrane protein LaaN; hypothetical protein 1409731..1410489 Lactococcus lactis subsp. lactis Il1403 1115021 NP_835318.1 CDS L200054 NC_002662.1 1410555 1410908 R hypothetical protein complement(1410555..1410908) Lactococcus lactis subsp. lactis Il1403 1115022 NP_267528.1 CDS yobA NC_002662.1 1411005 1411433 R hypothetical protein complement(1411005..1411433) Lactococcus lactis subsp. lactis Il1403 1115023 NP_267529.1 CDS arsC NC_002662.1 1411744 1412145 R adaptations and atypical conditions; arsenate reductase complement(1411744..1412145) Lactococcus lactis subsp. lactis Il1403 1115024 NP_267530.1 CDS yobC NC_002662.1 1412261 1412443 D hypothetical protein 1412261..1412443 Lactococcus lactis subsp. lactis Il1403 1115025 NP_267531.1 CDS pi301 NC_002662.1 1414112 1414642 R similar to orf258 of Lactococcus lactis phage BK5-T; prophage pi3 protein 01 complement(1414112..1414642) Lactococcus lactis subsp. lactis Il1403 1115026 NP_267532.1 CDS pi302 NC_002662.1 1414831 1415064 D prophage pi3 protein 02 1414831..1415064 Lactococcus lactis subsp. lactis Il1403 1115027 NP_267533.1 CDS pi303 NC_002662.1 1415364 1415534 R prophage pi3 protein 03 complement(1415364..1415534) Lactococcus lactis subsp. lactis Il1403 1115028 NP_267534.1 CDS pi304 NC_002662.1 1415811 1416014 D prophage pi3 protein 04 1415811..1416014 Lactococcus lactis subsp. lactis Il1403 1115029 NP_267535.1 CDS pi305 NC_002662.1 1416048 1416827 R prophage pi3 protein 05; similar to Orf259 of Lactococcus lactis phage BK5-T; muramidase complement(1416048..1416827) Lactococcus lactis subsp. lactis Il1403 1115030 NP_267536.1 CDS pi306 NC_002662.1 1416827 1417126 R prophage pi3 protein 06; similar to Orf95 of Lactococcus lactis phage BK5-T; holin complement(1416827..1417126) Lactococcus lactis subsp. lactis Il1403 1115031 NP_267537.1 CDS pi307 NC_002662.1 1417152 1418714 R similar to Orf47 of bacteriophage r1t; prophage pi3 protein 07 complement(1417152..1418714) Lactococcus lactis subsp. lactis Il1403 1115032 NP_267538.1 CDS pi308 NC_002662.1 1418726 1418950 R similar to Orf75 of Lactococcus lactis phage BK5-T; prophage pi3 protein 08 complement(1418726..1418950) Lactococcus lactis subsp. lactis Il1403 1115033 NP_267539.1 CDS pi309 NC_002662.1 1418970 1421402 R similar to Orf1904 of Lactococcus lactis phage BK5-T; prophage pi3 protein 09 complement(1418970..1421402) Lactococcus lactis subsp. lactis Il1403 1115034 NP_267540.1 CDS pi310 NC_002662.1 1421380 1421553 R similar to Orf44 of Streptococcus thermophilus bacteriophage phi o1205; prophage pi3 protein 10 complement(1421380..1421553) Lactococcus lactis subsp. lactis Il1403 1115035 NP_267541.1 CDS pi311 NC_002662.1 1421553 1422674 R similar to gp373 of Streptococcus thermophilus bacteriophage sfi11; prophage pi3 protein 11 complement(1421553..1422674) Lactococcus lactis subsp. lactis Il1403 1115036 NP_267542.1 CDS pi312 NC_002662.1 1422690 1424477 R similar to Orf1904 of Lactococcus lactis phage BK5-T; prophage pi3 protein 12 complement(1422690..1424477) Lactococcus lactis subsp. lactis Il1403 1115037 NP_267543.1 CDS pi313 NC_002662.1 1424477 1426012 R tail component; similar to tail component protein Orf17 of Streptococcus thermophilus bacteriophage DT1; prophage pi3 protein 13 complement(1424477..1426012) Lactococcus lactis subsp. lactis Il1403 1115038 NP_267544.1 CDS pi314 NC_002662.1 1426015 1430937 R similar to minor capsid protein of Lactobacillus temperate phage phi g1e; prophage pi3 protein 14 complement(1426015..1430937) Lactococcus lactis subsp. lactis Il1403 1115039 NP_267545.1 CDS pi316 NC_002662.1 1431162 1431581 R tail component; similar to Orf14 encoding a tail component protein of Streptococcus thermophilus bacteriophage DT1; prophage pi3 protein 16 complement(1431162..1431581) Lactococcus lactis subsp. lactis Il1403 1115040 NP_267546.1 CDS pi317 NC_002662.1 1431726 1432319 R prophage pi3 protein 17; similar to major tail protein of Streptococcus thermophilus bacteriophage DT1; major tail protein complement(1431726..1432319) Lactococcus lactis subsp. lactis Il1403 1115041 NP_267547.1 CDS pi318 NC_002662.1 1432350 1432745 R tail component; similar to Orf12 encoding a tail component protein of Streptococcus thermophilus bacteriophage DT1; prophage pi3 protein 18 complement(1432350..1432745) Lactococcus lactis subsp. lactis Il1403 1115042 NP_267548.1 CDS pi319 NC_002662.1 1432742 1433248 R tail component; similar to 18K protein of Leuconostoc oenos phage L10; prophage pi3 protein 19 complement(1432742..1433248) Lactococcus lactis subsp. lactis Il1403 1115043 NP_267549.1 CDS pi320 NC_002662.1 1433250 1433600 R prophage pi3 protein 20; similar to head-tail joining protein of Streptococcus thermophilus bacteriophage DT1; head-tail joining protein complement(1433250..1433600) Lactococcus lactis subsp. lactis Il1403 1115044 NP_267550.1 CDS pi321 NC_002662.1 1433575 1433898 R similar to a hypothetical protein of Lactococcus lactis phage BK5-T; prophage pi3 protein 21 complement(1433575..1433898) Lactococcus lactis subsp. lactis Il1403 1115045 NP_267551.1 CDS pi322 NC_002662.1 1433914 1435140 R prophage pi3 protein 22; similar to major head protein precursor of Streptococcus thermophilus bacteriophage Sfi21; major head protein precursor complement(1433914..1435140) Lactococcus lactis subsp. lactis Il1403 1115046 NP_267552.1 CDS pi323 NC_002662.1 1435152 1435859 R prophage pi3 protein 23; ATP dependent Clp protease complement(1435152..1435859) Lactococcus lactis subsp. lactis Il1403 1115047 NP_267553.1 CDS pi324 NC_002662.1 1435902 1437080 R similar to orf387 gp of Streptococcus thermophilus bacteriophage Sfi19; prophage pi3 protein 24 complement(1435902..1437080) Lactococcus lactis subsp. lactis Il1403 1115048 NP_267554.1 CDS pi325 NC_002662.1 1437077 1437286 R prophage pi3 protein 25; similar to head-tail joining protein of Streptococcus thermophilus bacteriophage DT1; head-tail joining protein complement(1437077..1437286) Lactococcus lactis subsp. lactis Il1403 1115049 NP_267555.1 CDS pi326 NC_002662.1 1437255 1439228 R prophage pi3 protein 26; similar to terminase large subunit of Streptococcus thermophilus bacteriophage Sfi21; terminase large subunit complement(1437255..1439228) Lactococcus lactis subsp. lactis Il1403 1115050 NP_267556.1 CDS pi327 NC_002662.1 1439215 1439688 R prophage pi3 protein 27; similar to terminase small subunit of Streptococcus thermophilus bacteriophage Sfi21; terminase small subunit complement(1439215..1439688) Lactococcus lactis subsp. lactis Il1403 1115051 NP_267557.1 CDS pi328 NC_002662.1 1439817 1440332 R similar to orf170 of Streptococcus thermophilus bacteriophage Sfi19; prophage pi3 protein 28 complement(1439817..1440332) Lactococcus lactis subsp. lactis Il1403 1115052 NP_267558.1 CDS pi329 NC_002662.1 1440334 1440639 R prophage pi3 protein 29 complement(1440334..1440639) Lactococcus lactis subsp. lactis Il1403 1115053 NP_267559.1 CDS pi330 NC_002662.1 1440787 1441209 R similar to a hypothetical protein of Lactococcus lactis accession number Y11901); prophage pi3 protein 30 complement(1440787..1441209) Lactococcus lactis subsp. lactis Il1403 1115054 NP_267560.1 CDS pi331 NC_002662.1 1441287 1441646 R prophage pi3 protein 31 complement(1441287..1441646) Lactococcus lactis subsp. lactis Il1403 1115055 NP_835319.1 CDS L200055 NC_002662.1 1441771 1441926 R similar to bacteriophage bIL286 Orf34; hypothetical protein complement(1441771..1441926) Lactococcus lactis subsp. lactis Il1403 1115056 NP_835320.1 CDS L200056 NC_002662.1 1441934 1442041 R hypothetical protein complement(1441934..1442041) Lactococcus lactis subsp. lactis Il1403 1115057 NP_267561.1 CDS pi332 NC_002662.1 1442107 1442301 R similar to orfX of bacteriophage 712 accession number AF087814; prophage pi3 protein 32 complement(1442107..1442301) Lactococcus lactis subsp. lactis Il1403 1115058 NP_835321.1 CDS L200057 NC_002662.1 1442298 1442441 R similar to bacteriophage bIL309 Orf27; hypothetical protein complement(1442298..1442441) Lactococcus lactis subsp. lactis Il1403 1115059 NP_267562.1 CDS pi333 NC_002662.1 1442460 1442795 R similar to Orf29 of the Lactococcus lactis lytic bacteriophage sk1; prophage pi3 protein 33 complement(1442460..1442795) Lactococcus lactis subsp. lactis Il1403 1115060 NP_267563.1 CDS pi334 NC_002662.1 1442817 1443161 R similar to Orf21 of bacteriophage r1t; prophage pi3 protein 34 complement(1442817..1443161) Lactococcus lactis subsp. lactis Il1403 1115061 NP_267564.1 CDS pi335 NC_002662.1 1443165 1443584 R prophage pi3 protein 35; de novo synthesis of thymidylate; similar to dUTPase of bacteriophage r1t; deoxyuridine 5'-triphosphate nucleotidohydrolase complement(1443165..1443584) Lactococcus lactis subsp. lactis Il1403 1115062 NP_267565.1 CDS pi336 NC_002662.1 1443581 1443868 R prophage pi3 protein 36 complement(1443581..1443868) Lactococcus lactis subsp. lactis Il1403 1115063 NP_267566.1 CDS pi337 NC_002662.1 1443865 1444521 R similar to Orf19 of bacteriophage r1t; prophage pi3 protein 37 complement(1443865..1444521) Lactococcus lactis subsp. lactis Il1403 1115064 NP_267567.1 CDS pi338 NC_002662.1 1444493 1444852 R similar to hypothetical protein 2 of bacteriophage T5; prophage pi3 protein 38 complement(1444493..1444852) Lactococcus lactis subsp. lactis Il1403 1115065 NP_267568.1 CDS pi339 NC_002662.1 1444861 1445370 R prophage pi3 protein 39 complement(1444861..1445370) Lactococcus lactis subsp. lactis Il1403 1115066 NP_267569.1 CDS pi340 NC_002662.1 1445385 1445957 R similar to Orf18 of bacteriophage r1t; prophage pi3 protein 40 complement(1445385..1445957) Lactococcus lactis subsp. lactis Il1403 1115067 NP_267570.1 CDS pi341 NC_002662.1 1445947 1446126 R similar to Orf17 of bacteriophage r1t; prophage pi3 protein 41 complement(1445947..1446126) Lactococcus lactis subsp. lactis Il1403 1115068 NP_267571.1 CDS pi342 NC_002662.1 1446148 1446438 R prophage pi3 protein 42 complement(1446148..1446438) Lactococcus lactis subsp. lactis Il1403 1115069 NP_267572.1 CDS pi343 NC_002662.1 1446550 1446789 R similar to Orf16 of bacteriophage r1t; prophage pi3 protein 43 complement(1446550..1446789) Lactococcus lactis subsp. lactis Il1403 1115070 NP_267573.1 CDS pi344 NC_002662.1 1446782 1447276 R similar to Orf15 of bacteriophage r1t; prophage pi3 protein 44 complement(1446782..1447276) Lactococcus lactis subsp. lactis Il1403 1115071 NP_267574.1 CDS pi345 NC_002662.1 1447273 1447647 R prophage pi3 protein 45 complement(1447273..1447647) Lactococcus lactis subsp. lactis Il1403 1115072 NP_835322.1 CDS L200058 NC_002662.1 1447628 1447801 R hypothetical protein complement(1447628..1447801) Lactococcus lactis subsp. lactis Il1403 1115073 NP_267575.1 CDS pi346 NC_002662.1 1447798 1448682 R prophage pi3 protein 46; similar to the orf12 of the phage r1t; similar to DnaC of Escherichia coli or DnaI of Bacillus subtilis, which are required for chromosomal replication; DNA replication protein complement(1447798..1448682) Lactococcus lactis subsp. lactis Il1403 1115074 NP_267576.1 CDS pi347 NC_002662.1 1448692 1449531 R prophage pi3 protein 47; similar to Rep2009 of bacteriophage Tuc2009; replisome organizer protein complement(1448692..1449531) Lactococcus lactis subsp. lactis Il1403 1115075 NP_267577.1 CDS pi348 NC_002662.1 1449659 1450084 R prophage pi3 protein 48; single strand binding helix destabilising protein complement(1449659..1450084) Lactococcus lactis subsp. lactis Il1403 1115076 NP_267578.1 CDS pi349 NC_002662.1 1450077 1450835 R prophage pi3 protein 49 complement(1450077..1450835) Lactococcus lactis subsp. lactis Il1403 1115077 NP_267579.1 CDS pi350 NC_002662.1 1450844 1451239 R similar to Orf10 of bacteriophage TP901-1; prophage pi3 protein 50 complement(1450844..1451239) Lactococcus lactis subsp. lactis Il1403 1115078 NP_267580.1 CDS pi351 NC_002662.1 1451354 1451569 R similar to Orf71 of Lactococcus bacteriophage phi31; prophage pi3 protein 51 complement(1451354..1451569) Lactococcus lactis subsp. lactis Il1403 1115079 NP_267581.1 CDS pi352 NC_002662.1 1451672 1451947 D similar to Orf10 of bacteriophage Tuc2009; prophage pi3 protein 52 1451672..1451947 Lactococcus lactis subsp. lactis Il1403 1115080 NP_267582.1 CDS pi353 NC_002662.1 1451944 1452138 R similar to Orf113 of Lactococcus lactis phage BK5-T; prophage pi3 protein 53 complement(1451944..1452138) Lactococcus lactis subsp. lactis Il1403 1115081 NP_267583.1 CDS pi354 NC_002662.1 1452281 1452571 R prophage pi3 protein 54 complement(1452281..1452571) Lactococcus lactis subsp. lactis Il1403 1115082 NP_267584.1 CDS pi355 NC_002662.1 1452584 1453294 R prophage pi3 protein 55; similar to P1-antirepressor homolog of Streptococcus thermophilus bacteriophage TP-J34; antirepressor complement(1452584..1453294) Lactococcus lactis subsp. lactis Il1403 1115083 NP_267585.1 CDS pi356 NC_002662.1 1453308 1453547 R prophage pi3 protein 56; similar to cro-like repressor of Streptococcus thermophilus bacteriophage Sfi21; Cro-like repressor complement(1453308..1453547) Lactococcus lactis subsp. lactis Il1403 1115084 NP_267586.1 CDS pi357 NC_002662.1 1453713 1454234 D prophage pi3 protein 57; similar to repressor of Lactobacillus casei bacteriophage A2; cI-like repressor 1453713..1454234 Lactococcus lactis subsp. lactis Il1403 1115085 NP_267587.1 CDS pi358 NC_002662.1 1454244 1454831 D prophage pi3 protein 58 1454244..1454831 Lactococcus lactis subsp. lactis Il1403 1115086 NP_267588.1 CDS pi359 NC_002662.1 1454896 1455747 D prophage pi3 protein 59 1454896..1455747 Lactococcus lactis subsp. lactis Il1403 1115087 NP_267589.1 CDS pi360 NC_002662.1 1455870 1456949 D prophage pi3 protein 60; integrase 1455870..1456949 Lactococcus lactis subsp. lactis Il1403 1115088 NP_267590.1 CDS yofM NC_002662.1 1457654 1457989 R similar to YlxM of Bacillus subtilis; DNA-binding protein complement(1457654..1457989) Lactococcus lactis subsp. lactis Il1403 1115089 NP_267591.1 CDS llrB NC_002662.1 1458173 1458883 D evidence experimental PMID:10708382; two-component systems; two-component system regulator 1458173..1458883 Lactococcus lactis subsp. lactis Il1403 1115090 NP_267592.1 CDS kinB NC_002662.1 1458873 1460426 D evidence experimental PMID:9172368; two-component systems; sensor protein kinase 1458873..1460426 Lactococcus lactis subsp. lactis Il1403 1115091 NP_835323.1 CDS yogA NC_002662.1 1460604 1460966 D similar to Lactococcus lactis TcsBorf2; in the same operon as lrrB and kinB; hypothetical protein 1460604..1460966 Lactococcus lactis subsp. lactis Il1403 1115092 NP_267593.1 CDS rgrB NC_002662.1 1460974 1461681 R GntR-family regulator; probably ranscriptional regulator of acetyl-CoA synthesis (by the vicinity of corresponding genes); GntR family transcriptional regulator complement(1460974..1461681) Lactococcus lactis subsp. lactis Il1403 1115093 NP_267594.1 CDS bmpA NC_002662.1 1461873 1462925 R membranes, lipoproteins, and porins; attached to membrane by a lipid anchor; BMP family of lipoproteins; basic membrane protein A complement(1461873..1462925) Lactococcus lactis subsp. lactis Il1403 1115094 NP_267595.1 CDS cdd NC_002662.1 1463184 1463576 R salvage of nucleosides and nucleotides; cytidine deaminase complement(1463184..1463576) Lactococcus lactis subsp. lactis Il1403 1115095 NP_267596.1 CDS deoC NC_002662.1 1463563 1464225 R catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase complement(1463563..1464225) Lactococcus lactis subsp. lactis Il1403 1115096 NP_267597.1 CDS yogE NC_002662.1 1464238 1464426 R hypothetical protein complement(1464238..1464426) Lactococcus lactis subsp. lactis Il1403 1115097 NP_267598.1 CDS pdp NC_002662.1 1464428 1465720 R Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway; pyrimidine-nucleoside phosphorylase complement(1464428..1465720) Lactococcus lactis subsp. lactis Il1403 1115098 NP_267599.1 CDS yogG NC_002662.1 1465751 1466353 R SAM-dependent methyltransferase, evidenced by COGnitor; hypothetical protein complement(1465751..1466353) Lactococcus lactis subsp. lactis Il1403 1115099 NP_267600.1 CDS coaA NC_002662.1 1466541 1467461 D catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 1466541..1467461 Lactococcus lactis subsp. lactis Il1403 1115100 NP_267601.1 CDS yogI NC_002662.1 1467528 1467959 R phosphate-starvation-inducible protein PsiE complement(1467528..1467959) Lactococcus lactis subsp. lactis Il1403 1115101 NP_267602.1 CDS yogJ NC_002662.1 1468013 1468957 R transort and binding protein, cations; cation transporter complement(1468013..1468957) Lactococcus lactis subsp. lactis Il1403 1115102 NP_267603.1 CDS yogL NC_002662.1 1469252 1469554 R similar to EpsR of the epsRXABCDEFGHIJKL operon of Lactococcus lactis plasmid pNZ4000; transcriptional regulator complement(1469252..1469554) Lactococcus lactis subsp. lactis Il1403 1115103 NP_267604.1 CDS yogM NC_002662.1 1469635 1470177 R hypothetical protein complement(1469635..1470177) Lactococcus lactis subsp. lactis Il1403 1115104 NP_267605.1 CDS yohC NC_002662.1 1471753 1472319 D belongs to TetR/AcrR family; transcriptional regulator 1471753..1472319 Lactococcus lactis subsp. lactis Il1403 1115106 NP_267606.1 CDS yohD NC_002662.1 1472367 1472537 R hypothetical protein complement(1472367..1472537) Lactococcus lactis subsp. lactis Il1403 1115107 NP_267607.1 CDS busAB NC_002662.1 1472729 1474450 R evidence experimental PMID:10515910; transport and binding protein; amino acids, peptides and amines. involved in osmoprotection. Permease and substrate binding functions are in the same protein; betaine ABC transporter permease and substrate binding protein complement(1472729..1474450) Lactococcus lactis subsp. lactis Il1403 1115108 NP_267608.1 CDS busAA NC_002662.1 1474447 1475673 R evidence experimental PMID:10515910; transport and binding protein; amino acids, peptides and amines. involved in osmoprotection; betaine ABC transporter ATP binding protein complement(1474447..1475673) Lactococcus lactis subsp. lactis Il1403 1115109 NP_267609.1 CDS busR NC_002662.1 1475885 1476505 R GntR-family regulators; similar to fatty acid responsive regulator of Escherichia coli; probably an osmotic shock responce regulator from vicinity of corresponding genes; GntR family transcriptional regulator complement(1475885..1476505) Lactococcus lactis subsp. lactis Il1403 1115110 NP_267610.1 CDS yohH NC_002662.1 1476721 1478346 R surface polysaccharides, lipopolysaccharides and antigens; lipopolysaccharide biosynthesis protein complement(1476721..1478346) Lactococcus lactis subsp. lactis Il1403 1115111 NP_267611.1 CDS yohJ NC_002662.1 1478370 1479890 R surface polysaccharides, lipopolysaccharides and antigens; lipopolysaccharide biosynthesis protein complement(1478370..1479890) Lactococcus lactis subsp. lactis Il1403 1115112 NP_267612.1 CDS yoiA NC_002662.1 1479930 1483202 R hypothetical protein complement(1479930..1483202) Lactococcus lactis subsp. lactis Il1403 1115113 NP_267613.1 CDS yoiB NC_002662.1 1483349 1484296 R hypothetical protein complement(1483349..1484296) Lactococcus lactis subsp. lactis Il1403 1115114 NP_267614.1 CDS yoiC NC_002662.1 1484512 1488837 R hypothetical protein complement(1484512..1488837) Lactococcus lactis subsp. lactis Il1403 1115115 NP_267615.1 CDS bglH NC_002662.1 1489446 1490882 R energy metabolism, sugars; beta-glucosidase complement(1489446..1490882) Lactococcus lactis subsp. lactis Il1403 1115116 NP_267616.1 CDS ptbA NC_002662.1 1490930 1492840 R transport and binding protein; PTS system; PTS system beta-glucoside-specific transporter subunit IIABC complement(1490930..1492840) Lactococcus lactis subsp. lactis Il1403 1115117 NP_267617.1 CDS bglR NC_002662.1 1492982 1493791 R evidence experimental PMID:8083160; BglG-family regulator; beta-glucoside operon antiterminator complement(1492982..1493791) Lactococcus lactis subsp. lactis Il1403 1115118 NP_267618.1 CDS trpA NC_002662.1 1493956 1494717 R catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha complement(1493956..1494717) Lactococcus lactis subsp. lactis Il1403 1115119 NP_267619.1 CDS trpB NC_002662.1 1494714 1495922 R catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta complement(1494714..1495922) Lactococcus lactis subsp. lactis Il1403 1115120 NP_267622.1 CDS trpF NC_002662.1 1496508 1497563 R evidence experimental PMID:1400208; aromatic amino-acid family; phosphorybosyl-anthranilate isomerase complement(1496508..1497563) Lactococcus lactis subsp. lactis Il1403 1115123 NP_267623.1 CDS trpC NC_002662.1 1497553 1498347 R involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; Indole-3-glycerol phosphate synthase complement(1497553..1498347) Lactococcus lactis subsp. lactis Il1403 1115124 NP_267624.2 CDS trpD NC_002662.1 1498394 1499401 R Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase complement(1498394..1499401) Lactococcus lactis subsp. lactis Il1403 1115125 NP_267625.1 CDS trpG NC_002662.1 1499391 1499987 R TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II complement(1499391..1499987) Lactococcus lactis subsp. lactis Il1403 1115126 NP_267626.1 CDS trpE NC_002662.1 1500112 1501482 R with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I complement(1500112..1501482) Lactococcus lactis subsp. lactis Il1403 1115127 NP_267627.1 CDS ypaA NC_002662.1 1501940 1502299 R hypothetical protein complement(1501940..1502299) Lactococcus lactis subsp. lactis Il1403 1115128 NP_267628.1 CDS rmaC NC_002662.1 1502314 1503384 R MarR-family regulator; N-terminal part similar to the MarR family of transcription regulators; C-terminal part similar to NAD(P)H nitroreductases; transcriptional regulator complement(1502314..1503384) Lactococcus lactis subsp. lactis Il1403 1115129 NP_267629.1 CDS ypaC NC_002662.1 1503498 1504241 R SAM-dependent methyltransferase, evidenced by COGnitor; hypothetical protein complement(1503498..1504241) Lactococcus lactis subsp. lactis Il1403 1115130 NP_267630.1 CDS ypaD NC_002662.1 1504317 1504997 R hypothetical protein complement(1504317..1504997) Lactococcus lactis subsp. lactis Il1403 1115131 NP_267631.1 CDS ypaE NC_002662.1 1504997 1505686 R hypothetical protein complement(1504997..1505686) Lactococcus lactis subsp. lactis Il1403 1115132 NP_267632.1 CDS fur NC_002662.1 1505812 1506198 D general regulatory function; ferric uptake regulator 1505812..1506198 Lactococcus lactis subsp. lactis Il1403 1115133 NP_267633.1 CDS ypaG NC_002662.1 1506344 1506691 D hypothetical protein 1506344..1506691 Lactococcus lactis subsp. lactis Il1403 1115134 NP_267634.1 CDS ypaH NC_002662.1 1506887 1507774 D hypothetical protein 1506887..1507774 Lactococcus lactis subsp. lactis Il1403 1115135 NP_267635.1 CDS rmeB NC_002662.1 1507815 1508249 R MerR family of transcription regulators; transcriptional regulator complement(1507815..1508249) Lactococcus lactis subsp. lactis Il1403 1115136 NP_267636.2 CDS ypaI NC_002662.1 1508326 1509057 D aerobic energy metabolism; short-chain dehydrogenase, evidenced by COGnitor; oxidoreductase 1508326..1509057 Lactococcus lactis subsp. lactis Il1403 1115137 NP_267637.1 CDS dxsA NC_002662.1 1509163 1510962 R catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase complement(1509163..1510962) Lactococcus lactis subsp. lactis Il1403 1115138 NP_267638.1 CDS rmaE NC_002662.1 1511212 1511631 R MarR-family regulator; MarR family transcriptional regulator complement(1511212..1511631) Lactococcus lactis subsp. lactis Il1403 1115139 NP_267639.1 CDS ypbB NC_002662.1 1511813 1512718 D transport and binding protein, cations; similar to several magnesium and cobalt transporters; cationic transporter 1511813..1512718 Lactococcus lactis subsp. lactis Il1403 1115140 NP_267640.1 CDS ypbC NC_002662.1 1512823 1514202 D hypothetical protein 1512823..1514202 Lactococcus lactis subsp. lactis Il1403 1115141 NP_267641.1 CDS ypbD NC_002662.1 1514246 1515991 R transport and binding protein, carbohydrates; organic alcohols and acids; sugar transport symporter complement(1514246..1515991) Lactococcus lactis subsp. lactis Il1403 1115142 NP_267642.1 CDS guaA NC_002662.1 1516220 1517761 R contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase complement(1516220..1517761) Lactococcus lactis subsp. lactis Il1403 1115143 NP_267643.1 CDS scrK NC_002662.1 1517970 1518845 R energy metabolism, sugars; similar to the sacK encoded fructokinase of Lactococcus lactis cremoris NZ9800; fructokinase complement(1517970..1518845) Lactococcus lactis subsp. lactis Il1403 1115144 NP_267644.1 CDS ypbG NC_002662.1 1518948 1519829 R energy metabolism, sugars; similar to different sugar kinases; sugar kinase complement(1518948..1519829) Lactococcus lactis subsp. lactis Il1403 1115145 NP_267645.1 CDS ypcA NC_002662.1 1519866 1521293 R energy metabolism, sugars; cellulose degradation pathway; beta-glucosidase complement(1519866..1521293) Lactococcus lactis subsp. lactis Il1403 1115146 NP_267646.1 CDS ypcB NC_002662.1 1521323 1521931 R hypothetical protein complement(1521323..1521931) Lactococcus lactis subsp. lactis Il1403 1115147 NP_267649.1 CDS dexB NC_002662.1 1524880 1526427 R degradation of polysaccharides; alpha 1-6-glucosidase complement(1524880..1526427) Lactococcus lactis subsp. lactis Il1403 1115150 NP_267650.1 CDS lnbA NC_002662.1 1526420 1527397 R degradation of polysaccharides; similar to lacto-N-biosidase precursor of Streptomyces sp, the enzyme, which releases lacto-N-biose from oligosaccharides; lacto-N-biosidase complement(1526420..1527397) Lactococcus lactis subsp. lactis Il1403 1115151 NP_267651.1 CDS ypcG NC_002662.1 1527475 1528926 R transport and binding protein, carbohydrates; organic alcohols and acids; attached to the membrance by a lipid anchor; sugar ABC transporter substrate binding protein complement(1527475..1528926) Lactococcus lactis subsp. lactis Il1403 1115152 NP_267652.1 CDS ypcH NC_002662.1 1529029 1529949 R transport and binding protein, carbohydrates; organic alcohols and acids; sugar ABC transporter permease complement(1529029..1529949) Lactococcus lactis subsp. lactis Il1403 1115153 NP_267653.1 CDS ypdA NC_002662.1 1530005 1530937 R transport and binding protein, carbohydrates; organic alcohols and acids; sugar ABC transporter substrate binding protein complement(1530005..1530937) Lactococcus lactis subsp. lactis Il1403 1115154 NP_267654.1 CDS ypdB NC_002662.1 1530934 1533633 R similar to different alpha-mannosidases; sugar hydrolase complement(1530934..1533633) Lactococcus lactis subsp. lactis Il1403 1115155 NP_267655.1 CDS ypdC NC_002662.1 1533668 1534963 R hypothetical protein complement(1533668..1534963) Lactococcus lactis subsp. lactis Il1403 1115156 NP_267656.1 CDS rliB NC_002662.1 1535202 1536239 D LacI-family regulators; regulator of a polysacharide utilization operon. Highest similarity to L-arabinose utilization regulators from bacilli; transcriptional regulator 1535202..1536239 Lactococcus lactis subsp. lactis Il1403 1115157 NP_267657.1 CDS ypdD NC_002662.1 1536236 1538389 D sugars; similar to alpha-1,2-mannosidase of Bacillus sp. M-90; sugar hydrolase 1536236..1538389 Lactococcus lactis subsp. lactis Il1403 1115158 NP_267658.1 CDS ptk NC_002662.1 1538482 1540950 R phosphoketolase complement(1538482..1540950) Lactococcus lactis subsp. lactis Il1403 1115159 NP_267659.1 CDS xylT NC_002662.1 1541108 1542409 R transport and binding protein, carbohydrates; organic alcohols and acids; D-xylose proton-symporter complement(1541108..1542409) Lactococcus lactis subsp. lactis Il1403 1115160 NP_267660.1 CDS xylX NC_002662.1 1542578 1543180 R sugars; acetyltransferase in xylose utilization operon; acetyltransferase complement(1542578..1543180) Lactococcus lactis subsp. lactis Il1403 1115161 NP_267661.1 CDS xynB NC_002662.1 1543238 1544917 R sugars; intracellular xylan-degrading enzyme; beta-1,4-xylosidase complement(1543238..1544917) Lactococcus lactis subsp. lactis Il1403 1115162 NP_267662.2 CDS xynT NC_002662.1 1544942 1546426 R transport and binding protein, carbohydrates; organic alcohols and acids; xylose utilization; sodium:galactosidase symporter family; xyloside transporter complement(1544942..1546426) Lactococcus lactis subsp. lactis Il1403 1115163 NP_267663.1 CDS xylM NC_002662.1 1546480 1547484 R sugars; xylose utilization; may act on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; aldose 1-epimerase complement(1546480..1547484) Lactococcus lactis subsp. lactis Il1403 1115164 NP_267664.1 CDS xylB NC_002662.1 1547487 1548992 R sugars; xylose utilization; xylulose kinase complement(1547487..1548992) Lactococcus lactis subsp. lactis Il1403 1115165 NP_267665.1 CDS xylA NC_002662.1 1549053 1550372 R catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase complement(1549053..1550372) Lactococcus lactis subsp. lactis Il1403 1115166 NP_267666.1 CDS xylR NC_002662.1 1550477 1551460 D AraC-family regulators; xylose operon regulator 1550477..1551460 Lactococcus lactis subsp. lactis Il1403 1115167 NP_267667.1 CDS purK NC_002662.1 1551581 1552630 R With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit complement(1551581..1552630) Lactococcus lactis subsp. lactis Il1403 1115168 NP_267668.1 CDS purE NC_002662.1 1552738 1553223 R evidence experimental PMID:9797284; catalytic subunit; sixth step in de novo purine biosynthesis; phosphoribosylaminoimidazole carboxylase complement(1552738..1553223) Lactococcus lactis subsp. lactis Il1403 1115169 NP_267669.1 CDS purD NC_002662.1 1553256 1554497 R catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase complement(1553256..1554497) Lactococcus lactis subsp. lactis Il1403 1115170 NP_267670.1 CDS ypfD NC_002662.1 1554850 1555476 D TerR/AcrR family; transcriptional regulator 1554850..1555476 Lactococcus lactis subsp. lactis Il1403 1115171 NP_267671.1 CDS tra983F NC_002662.1 1555588 1556535 D transposon related function; belongs to the IS30 family of transposase; transposase of IS983F 1555588..1556535 Lactococcus lactis subsp. lactis Il1403 1115172 NP_267672.1 CDS ypfE NC_002662.1 1556660 1558048 D transport and binding protein; multidrug resistance; similar to many multidrug resistance transporters; transporter 1556660..1558048 Lactococcus lactis subsp. lactis Il1403 1115173 NP_267673.1 CDS ypfF NC_002662.1 1558092 1558784 R similar to a hypothetical protein YfnB of Bacillus subtilis; hypothetical protein complement(1558092..1558784) Lactococcus lactis subsp. lactis Il1403 1115174 NP_267674.1 CDS purH NC_002662.1 1558961 1560517 R involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase complement(1558961..1560517) Lactococcus lactis subsp. lactis Il1403 1115175 NP_267675.1 CDS hprT NC_002662.1 1560693 1561235 R purine biosynthesis or salvage; hypoxanthine-guanine phosphoribosyltransferase complement(1560693..1561235) Lactococcus lactis subsp. lactis Il1403 1115176 NP_267676.1 CDS ypgB NC_002662.1 1561372 1562409 R aerobic energy metabolism; similar to many reductases involved in flavonoid metabolism in plants; nucleoside-diphosphate-sugar epimerase, evidenced by COGnitor; oxidoreductase complement(1561372..1562409) Lactococcus lactis subsp. lactis Il1403 1115177 NP_267677.1 CDS ypgC NC_002662.1 1562540 1563070 D general regulatory function; transcriptional regulator 1562540..1563070 Lactococcus lactis subsp. lactis Il1403 1115178 NP_267678.1 CDS ypgD NC_002662.1 1563121 1564710 R transport and binding protein; ABC transporter ATP-binding protein/permease complement(1563121..1564710) Lactococcus lactis subsp. lactis Il1403 1115179 NP_267679.1 CDS purN NC_002662.1 1564877 1565425 R glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase complement(1564877..1565425) Lactococcus lactis subsp. lactis Il1403 1115180 NP_267680.1 CDS purM NC_002662.1 1565453 1566469 R catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase complement(1565453..1566469) Lactococcus lactis subsp. lactis Il1403 1115181 NP_267681.1 CDS clpB NC_002662.1 1566658 1569261 R evidence experimental PMID:10094684; adaptations and atypical conditions; ATPase subunit of intracellular ATP-dependent protease; ClpB protein complement(1566658..1569261) Lactococcus lactis subsp. lactis Il1403 1115182 NP_267682.1 CDS ypgH NC_002662.1 1569495 1570835 D hypothetical protein 1569495..1570835 Lactococcus lactis subsp. lactis Il1403 1115183 NP_267683.1 CDS yphA NC_002662.1 1570868 1571491 R aerobic energy metabolism; similar to NADH dehydrogenase of Aquifex aeolicus; NADH dehydrogenase complement(1570868..1571491) Lactococcus lactis subsp. lactis Il1403 1115184 NP_267684.1 CDS purF NC_002662.1 1571601 1573100 R Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase complement(1571601..1573100) Lactococcus lactis subsp. lactis Il1403 1115185 NP_267685.1 CDS yphC NC_002662.1 1573215 1574060 R aerobic energy metabolism; similar to many hypothetical oxidoreductases; oxidoreductase complement(1573215..1574060) Lactococcus lactis subsp. lactis Il1403 1115186 NP_267686.1 CDS purL NC_002662.1 1574172 1576391 R catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase II complement(1574172..1576391) Lactococcus lactis subsp. lactis Il1403 1115187 NP_267687.1 CDS purQ NC_002662.1 1576611 1577282 R catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase I complement(1576611..1577282) Lactococcus lactis subsp. lactis Il1403 1115188 NP_267688.1 CDS yphF NC_002662.1 1577282 1577545 R similar to YexA of Bacillus subtilis; hypothetical protein complement(1577282..1577545) Lactococcus lactis subsp. lactis Il1403 1115189 NP_267689.1 CDS purC NC_002662.1 1577601 1578311 R catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazolesuccinocarboxamide synthase complement(1577601..1578311) Lactococcus lactis subsp. lactis Il1403 1115190 NP_267690.1 CDS yphH NC_002662.1 1578455 1578856 R similar to TM1010 of Thermotoga maritima; hypothetical protein complement(1578455..1578856) Lactococcus lactis subsp. lactis Il1403 1115191 NP_267691.1 CDS yphI NC_002662.1 1578872 1579165 R hypothetical protein complement(1578872..1579165) Lactococcus lactis subsp. lactis Il1403 1115192 NP_267692.1 CDS yphJ NC_002662.1 1579184 1579492 R similar to C-terminal part of several 4-carboxymuconolactone decarboxylases; hypothetical protein complement(1579184..1579492) Lactococcus lactis subsp. lactis Il1403 1115193 NP_267693.1 CDS yphK NC_002662.1 1579528 1579896 R hypothetical protein complement(1579528..1579896) Lactococcus lactis subsp. lactis Il1403 1115194 NP_267694.1 CDS ypiA NC_002662.1 1579911 1580663 R aerobic energy metabolism; oxidoreductase complement(1579911..1580663) Lactococcus lactis subsp. lactis Il1403 1115195 NP_267695.1 CDS ypiB NC_002662.1 1580887 1582260 R transport and binding protein; multidrug resistance; similar to several multidrug resistance proteins; transporter complement(1580887..1582260) Lactococcus lactis subsp. lactis Il1403 1115196 NP_267696.1 CDS rmaI NC_002662.1 1582257 1582703 R MarR-family regulators; transcriptional regulator complement(1582257..1582703) Lactococcus lactis subsp. lactis Il1403 1115197 NP_267697.1 CDS thyA NC_002662.1 1582810 1583649 R ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase complement(1582810..1583649) Lactococcus lactis subsp. lactis Il1403 1115198 NP_267698.1 CDS ypiE NC_002662.1 1583745 1584197 R hypothetical protein complement(1583745..1584197) Lactococcus lactis subsp. lactis Il1403 1115199 NP_267699.1 CDS ypiH NC_002662.1 1584827 1585399 R hypothetical protein complement(1584827..1585399) Lactococcus lactis subsp. lactis Il1403 1115201 NP_835324.1 CDS L200062 NC_002662.1 1585482 1585781 R hypothetical protein complement(1585482..1585781) Lactococcus lactis subsp. lactis Il1403 1115202 NP_267700.1 CDS tra981H NC_002662.1 1585849 1586688 R evidence experimental PMID:8389385; transposon related function; related to a family of IS elements that includes IS2, IS3, IS150, IS600, IS629, IS861, IS904 and ISL1; transposase of IS981H complement(1585849..1586688) Lactococcus lactis subsp. lactis Il1403 1115203 NP_267701.1 CDS ypiI NC_002662.1 1586700 1586960 R transposon related function; similar to orf1 of IS981; transposase complement(1586700..1586960) Lactococcus lactis subsp. lactis Il1403 1115204 NP_267702.1 CDS ypiJ NC_002662.1 1586997 1587314 R hypothetical protein complement(1586997..1587314) Lactococcus lactis subsp. lactis Il1403 1115205 NP_267703.1 CDS ypiK NC_002662.1 1587265 1587912 R hypothetical protein complement(1587265..1587912) Lactococcus lactis subsp. lactis Il1403 1115206 NP_267704.1 CDS ypiL NC_002662.1 1587916 1590348 R similar to YcdJ and YigE; hypothetical protein complement(1587916..1590348) Lactococcus lactis subsp. lactis Il1403 1115207 NP_267705.1 CDS ypjA NC_002662.1 1590528 1591574 R aerobic energy metabolism; similar to several alcohol dehydrogenases; dehydrogenase complement(1590528..1591574) Lactococcus lactis subsp. lactis Il1403 1115208 NP_267706.1 CDS ypjB NC_002662.1 1591686 1591955 R hypothetical protein complement(1591686..1591955) Lactococcus lactis subsp. lactis Il1403 1115209 NP_267707.1 CDS ypjC NC_002662.1 1592015 1592722 R hypothetical protein complement(1592015..1592722) Lactococcus lactis subsp. lactis Il1403 1115210 NP_267708.1 CDS pydA NC_002662.1 1592839 1593774 R catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; subclass 1A is a dimer formed by two identical PyrD subunits each containing an FMN group; dihydroorotate dehydrogenase 1A complement(1592839..1593774) Lactococcus lactis subsp. lactis Il1403 1115211 NP_267709.1 CDS pmsX NC_002662.1 1593915 1594466 D translation protein modification; involved in posttranslational protein modification; peptide methionine sulfoxide reductase 1593915..1594466 Lactococcus lactis subsp. lactis Il1403 1115212 NP_267710.1 CDS ypjF NC_002662.1 1594476 1595450 R aerobic energy metabolism; oxidoreductase complement(1594476..1595450) Lactococcus lactis subsp. lactis Il1403 1115213 NP_267711.1 CDS ypjG NC_002662.1 1595665 1597536 R transport and binding protein. contains two ATP binding domains; ABC transporter ATP-binding protein complement(1595665..1597536) Lactococcus lactis subsp. lactis Il1403 1115214 NP_267712.1 CDS ypjH NC_002662.1 1598735 1599811 R aerobic energy metabolism; similar to several glycerol dehydrogenases; oxidoreductase complement(1598735..1599811) Lactococcus lactis subsp. lactis Il1403 1115216 NP_267713.1 CDS ypjI NC_002662.1 1599914 1600459 R hypothetical protein complement(1599914..1600459) Lactococcus lactis subsp. lactis Il1403 1115217 NP_267714.1 CDS pepDB NC_002662.1 1600574 1601998 R degradation of proteins, peptides, and glycopeptides; similar to dipeptidase PepD of Lactobacillus helveticus; dipeptidase complement(1600574..1601998) Lactococcus lactis subsp. lactis Il1403 1115218 NP_267715.2 CDS papL NC_002662.1 1602114 1603310 R catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity; tRNA CCA-pyrophosphorylase complement(1602114..1603310) Lactococcus lactis subsp. lactis Il1403 1115219 NP_267716.1 CDS yqaB NC_002662.1 1603530 1604066 R hypothetical protein complement(1603530..1604066) Lactococcus lactis subsp. lactis Il1403 1115220 NP_267717.1 CDS dapB NC_002662.1 1604115 1604897 R catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase complement(1604115..1604897) Lactococcus lactis subsp. lactis Il1403 1115221 NP_267718.1 CDS yqaC NC_002662.1 1604998 1605843 R similar to DegV of Bacillus subtilis; hypothetical protein complement(1604998..1605843) Lactococcus lactis subsp. lactis Il1403 1115222 NP_267719.1 CDS yqaD NC_002662.1 1605861 1606253 R hypothetical protein complement(1605861..1606253) Lactococcus lactis subsp. lactis Il1403 1115223 NP_267720.2 CDS trmD NC_002662.1 1606379 1607122 R methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase complement(1606379..1607122) Lactococcus lactis subsp. lactis Il1403 1115224 NP_267721.1 CDS rimM NC_002662.1 1607127 1607642 R Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM complement(1607127..1607642) Lactococcus lactis subsp. lactis Il1403 1115225 NP_267722.1 CDS yqaG NC_002662.1 1607814 1608641 R probably hydrolase, lysophospholipase, evidenced by COGnitor; hypothetical protein complement(1607814..1608641) Lactococcus lactis subsp. lactis Il1403 1115226 NP_267723.1 CDS hemH NC_002662.1 1608782 1609726 R protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase complement(1608782..1609726) Lactococcus lactis subsp. lactis Il1403 1115227 NP_267724.1 CDS yqbA NC_002662.1 1609988 1610227 R hypothetical protein complement(1609988..1610227) Lactococcus lactis subsp. lactis Il1403 1115228 NP_267725.1 CDS rpsP NC_002662.1 1610323 1610595 R binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 complement(1610323..1610595) Lactococcus lactis subsp. lactis Il1403 1115229 NP_267726.1 CDS mvaA NC_002662.1 1610684 1611916 R surface polysaccharides, lipopolysaccharides and antigens; hydroxymethylglutaryl-CoA reductase complement(1610684..1611916) Lactococcus lactis subsp. lactis Il1403 1115230 NP_267727.1 CDS thiL NC_002662.1 1611996 1613135 R fatty acid and phospholipid metabolism; acetyl coenzyme A acetyltransferase complement(1611996..1613135) Lactococcus lactis subsp. lactis Il1403 1115231 NP_267728.1 CDS hmcM NC_002662.1 1613444 1614598 D fatty acid and phospholipid metabolism; potentially involved in some intermediate steps for the synthesis of a polyketide molecule which may be involved in secondary metabolism; hydroxymethylglutaryl-CoA synthase 1613444..1614598 Lactococcus lactis subsp. lactis Il1403 1115232 NP_267729.1 CDS nagB NC_002662.1 1614659 1615366 R amino sugars; similar to glucosamine-6-P isomerase of Bacillus subtilis; glucosamine-6-P isomerase complement(1614659..1615366) Lactococcus lactis subsp. lactis Il1403 1115233 NP_267730.1 CDS yqbF NC_002662.1 1615518 1616480 R hypothetical protein complement(1615518..1616480) Lactococcus lactis subsp. lactis Il1403 1115234 NP_267731.1 CDS queA NC_002662.1 1616777 1617814 D Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 1616777..1617814 Lactococcus lactis subsp. lactis Il1403 1115235 NP_267732.1 CDS yqbH NC_002662.1 1617891 1618202 R similar to EpsR of the epsRXABCDEFGHIJKL operon of Lactococcus lactis plasmid pNZ4000; transcriptional regulator complement(1617891..1618202) Lactococcus lactis subsp. lactis Il1403 1115236 NP_267735.1 CDS yqbK NC_002662.1 1619579 1624528 R similar to leucine-rich proteins; hypothetical protein complement(1619579..1624528) Lactococcus lactis subsp. lactis Il1403 1115239 NP_267736.1 CDS yqcA NC_002662.1 1624565 1625320 R hypothetical protein complement(1624565..1625320) Lactococcus lactis subsp. lactis Il1403 1115240 NP_267737.1 CDS yqcB NC_002662.1 1625358 1626116 R hypothetical protein complement(1625358..1626116) Lactococcus lactis subsp. lactis Il1403 1115241 NP_267738.1 CDS yqcC NC_002662.1 1626154 1626585 R hypothetical protein complement(1626154..1626585) Lactococcus lactis subsp. lactis Il1403 1115242 NP_267739.1 CDS yqcD NC_002662.1 1626973 1627818 R hypothetical protein complement(1626973..1627818) Lactococcus lactis subsp. lactis Il1403 1115243 NP_267740.1 CDS yqcE NC_002662.1 1627879 1627974 R hypothetical protein complement(1627879..1627974) Lactococcus lactis subsp. lactis Il1403 1115244 NP_267741.1 CDS yqcF NC_002662.1 1628791 1629408 D hypothetical protein 1628791..1629408 Lactococcus lactis subsp. lactis Il1403 1115245 NP_267742.1 CDS yqcG NC_002662.1 1629422 1629592 R hypothetical protein complement(1629422..1629592) Lactococcus lactis subsp. lactis Il1403 1115246 NP_267743.2 CDS obgE NC_002662.1 1629620 1630927 R essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE complement(1629620..1630927) Lactococcus lactis subsp. lactis Il1403 1115247 NP_267744.1 CDS ftsQ NC_002662.1 1631083 1632261 R cell division protein; required for initiation of cell division; hypothetical protein complement(1631083..1632261) Lactococcus lactis subsp. lactis Il1403 1115248 NP_267745.1 CDS murG NC_002662.1 1632262 1633335 R UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; UDP diphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase complement(1632262..1633335) Lactococcus lactis subsp. lactis Il1403 1115249 NP_267746.1 CDS murD NC_002662.1 1633545 1634897 R UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase complement(1633545..1634897) Lactococcus lactis subsp. lactis Il1403 1115250 NP_267747.1 CDS glnB NC_002662.1 1635388 1635729 R nitrogen regulatory protein P-II complement(1635388..1635729) Lactococcus lactis subsp. lactis Il1403 1115251 NP_267748.1 CDS amtB NC_002662.1 1635861 1637102 R ammonium transporter complement(1635861..1637102) Lactococcus lactis subsp. lactis Il1403 1115252 NP_267749.1 CDS kinA NC_002662.1 1637285 1638760 R evidence experimental PMID:9172368; two-component systems; sensor protein kinase complement(1637285..1638760) Lactococcus lactis subsp. lactis Il1403 1115253 NP_267750.1 CDS llrA NC_002662.1 1638768 1639460 R evidence experimental PMID:10708382; two-component systems; involved in arginine metabolism regulation; essential for acid stress resistance development.; two-component system regulator complement(1638768..1639460) Lactococcus lactis subsp. lactis Il1403 1115254 NP_267751.1 CDS yqdA NC_002662.1 1639616 1640146 R hypothetical protein complement(1639616..1640146) Lactococcus lactis subsp. lactis Il1403 1115255 NP_267752.1 CDS rpmE2 NC_002662.1 1640277 1640522 R RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 complement(1640277..1640522) Lactococcus lactis subsp. lactis Il1403 1115256 NP_267753.1 CDS yqeA NC_002662.1 1640678 1641109 R hypothetical protein complement(1640678..1641109) Lactococcus lactis subsp. lactis Il1403 1115257 NP_267754.1 CDS yqeB NC_002662.1 1641224 1641586 R hypothetical protein complement(1641224..1641586) Lactococcus lactis subsp. lactis Il1403 1115258 NP_267755.1 CDS yqeC NC_002662.1 1642071 1642592 R hypothetical protein complement(1642071..1642592) Lactococcus lactis subsp. lactis Il1403 1115259 NP_267756.1 CDS yqeD NC_002662.1 1642662 1643498 R probably a phosphohydrolase, evidenced by COGnitor; hypothetical protein complement(1642662..1643498) Lactococcus lactis subsp. lactis Il1403 1115260 NP_267757.1 CDS carA NC_002662.1 1644117 1645190 R catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit complement(1644117..1645190) Lactococcus lactis subsp. lactis Il1403 1115261 NP_267758.1 CDS pyrB NC_002662.1 1645253 1646185 R catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit complement(1645253..1646185) Lactococcus lactis subsp. lactis Il1403 1115262 NP_267759.1 CDS pyrP NC_002662.1 1646369 1647661 R transport and binding protein; nucleosides, purines and pyrimidines; uracil permease complement(1646369..1647661) Lactococcus lactis subsp. lactis Il1403 1115263 NP_267760.1 CDS pyrR NC_002662.1 1647756 1648277 R regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase complement(1647756..1648277) Lactococcus lactis subsp. lactis Il1403 1115264 NP_267761.1 CDS yqeH NC_002662.1 1648538 1649236 R hypothetical protein complement(1648538..1649236) Lactococcus lactis subsp. lactis Il1403 1115265 NP_267762.1 CDS rarA NC_002662.1 1649332 1649631 D ArsR family; transcriptional regulator 1649332..1649631 Lactococcus lactis subsp. lactis Il1403 1115266 NP_267763.1 CDS yqeI NC_002662.1 1649621 1650535 D transort and binding protein, cations; cation transport protein 1649621..1650535 Lactococcus lactis subsp. lactis Il1403 1115267 NP_267764.1 CDS proA NC_002662.1 1650618 1651859 R Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase complement(1650618..1651859) Lactococcus lactis subsp. lactis Il1403 1115268 NP_267765.1 CDS proB NC_002662.1 1651877 1652689 R catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase complement(1651877..1652689) Lactococcus lactis subsp. lactis Il1403 1115269 NP_267766.1 CDS yqfA NC_002662.1 1652819 1654291 R hypothetical protein complement(1652819..1654291) Lactococcus lactis subsp. lactis Il1403 1115270 NP_267767.1 CDS yqfB NC_002662.1 1654291 1654530 R hypothetical protein complement(1654291..1654530) Lactococcus lactis subsp. lactis Il1403 1115271 NP_267768.1 CDS yqfC NC_002662.1 1654657 1654983 R hypothetical protein complement(1654657..1654983) Lactococcus lactis subsp. lactis Il1403 1115272 NP_267769.1 CDS yqfD NC_002662.1 1654970 1655677 R transport and binding protein; amino acids, peptides and amines; amino acid permease complement(1654970..1655677) Lactococcus lactis subsp. lactis Il1403 1115273 NP_267770.1 CDS yqfE NC_002662.1 1655850 1656425 D hypothetical protein 1655850..1656425 Lactococcus lactis subsp. lactis Il1403 1115274 NP_267771.1 CDS yqfF NC_002662.1 1656507 1657049 D polyamine biosynthesis; regulates polyamine concentraion by their degradation; spermidine acetyltransferase 1656507..1657049 Lactococcus lactis subsp. lactis Il1403 1115275 NP_267772.1 CDS ffh NC_002662.1 1657076 1658632 R protein and peptide secretion; SRP family of GTP-binding proteins; signal recognition particle protein complement(1657076..1658632) Lactococcus lactis subsp. lactis Il1403 1115276 NP_267773.1 CDS yqfG NC_002662.1 1658711 1661929 R probably induced by the competence induction factor; hypothetical protein complement(1658711..1661929) Lactococcus lactis subsp. lactis Il1403 1115277 NP_267774.1 CDS yqgA NC_002662.1 1661978 1663690 R hypothetical protein complement(1661978..1663690) Lactococcus lactis subsp. lactis Il1403 1115278 NP_267775.1 CDS yqgG NC_002662.1 1664040 1664711 D transort and binding protein, cations; cation transport ATPase 1664040..1664711 Lactococcus lactis subsp. lactis Il1403 1115279 NP_267776.1 CDS dapA NC_002662.1 1664751 1665644 R catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase complement(1664751..1665644) Lactococcus lactis subsp. lactis Il1403 1115280 NP_267777.1 CDS yqgC NC_002662.1 1665985 1666440 R Probably ADP-ribose pyrophosphatase or mutT, evidenced by COGnitor; hypothetical protein complement(1665985..1666440) Lactococcus lactis subsp. lactis Il1403 1115281 NP_267778.1 CDS asd NC_002662.1 1666451 1667527 R catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase complement(1666451..1667527) Lactococcus lactis subsp. lactis Il1403 1115282 NP_267779.1 CDS yqgE NC_002662.1 1667622 1668485 R transport and binding protein, carbohydrates; organic alcohols and acids; similar to glycerol uptake facilitator GlpF of Bacillus subtilis; belongs to the transmembrane channel Mip family; transporter complement(1667622..1668485) Lactococcus lactis subsp. lactis Il1403 1115283 NP_267780.1 CDS yqgF NC_002662.1 1668857 1669111 R hypothetical protein complement(1668857..1669111) Lactococcus lactis subsp. lactis Il1403 1115284 NP_267781.1 CDS tkt NC_002662.1 1669206 1671182 R catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase complement(1669206..1671182) Lactococcus lactis subsp. lactis Il1403 1115285 NP_267782.1 CDS kdgA NC_002662.1 1671413 1672054 R catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase complement(1671413..1672054) Lactococcus lactis subsp. lactis Il1403 1115286 NP_267783.1 CDS kdgK NC_002662.1 1672057 1673007 R Entner-Doudoroff pathway; glucuronate utilization pathway; 2-dehydro-3-deoxygluconokinase complement(1672057..1673007) Lactococcus lactis subsp. lactis Il1403 1115287 NP_267784.1 CDS uxaC NC_002662.1 1673004 1674422 R catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase complement(1673004..1674422) Lactococcus lactis subsp. lactis Il1403 1115288 NP_267785.1 CDS yqhA NC_002662.1 1674419 1675312 R hypothetical protein complement(1674419..1675312) Lactococcus lactis subsp. lactis Il1403 1115289 NP_267786.1 CDS uxuT NC_002662.1 1675372 1676898 R transport and binding protein, carbohydrates; organic alcohols and acids; transporter in glucuronate utilization pathway; Na-galactoside symporter complement(1675372..1676898) Lactococcus lactis subsp. lactis Il1403 1115290 NP_267787.1 CDS uxuA NC_002662.1 1677084 1678160 R catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase complement(1677084..1678160) Lactococcus lactis subsp. lactis Il1403 1115291 NP_267788.1 CDS uxuB NC_002662.1 1678399 1680033 R sugars; glucuronate utilization pathway; fructuronate reductase complement(1678399..1680033) Lactococcus lactis subsp. lactis Il1403 1115292 NP_267789.1 CDS kdgR NC_002662.1 1680202 1680885 D probably regulates uronic acid metabolism; GntR family transcriptional regulator 1680202..1680885 Lactococcus lactis subsp. lactis Il1403 1115293 NP_267790.1 CDS yqiA NC_002662.1 1680931 1682361 R transport and binding protein; multidrug resistance; belongs to the major facilitator family, also know as drug resistance translocase family; multidrug transporter complement(1680931..1682361) Lactococcus lactis subsp. lactis Il1403 1115294 NP_267791.1 CDS rbsB NC_002662.1 1682562 1683536 R transport and binding protein, carbohydrates; organic alcohols and acids; ribose ABC transporter substrate binding protein complement(1682562..1683536) Lactococcus lactis subsp. lactis Il1403 1115295 NP_267792.1 CDS rbsC NC_002662.1 1683548 1684489 R transport and binding protein, carbohydrates; organic alcohols and acids; ribose ABC transporter permease complement(1683548..1684489) Lactococcus lactis subsp. lactis Il1403 1115296 NP_267793.1 CDS rbsA NC_002662.1 1684492 1685970 R transport and binding protein, carbohydrates; organic alcohols and acids; ribose ABC transporter ATP binding protein complement(1684492..1685970) Lactococcus lactis subsp. lactis Il1403 1115297 NP_267794.1 CDS rbsD NC_002662.1 1685989 1686387 R cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase complement(1685989..1686387) Lactococcus lactis subsp. lactis Il1403 1115298 NP_267795.1 CDS rbsK NC_002662.1 1686409 1687311 R energy metabolism, sugars; ribokinase complement(1686409..1687311) Lactococcus lactis subsp. lactis Il1403 1115299 NP_267796.1 CDS rbsR NC_002662.1 1687322 1688305 R LacI-family regulators; ribose operon repressor complement(1687322..1688305) Lactococcus lactis subsp. lactis Il1403 1115300 NP_267797.1 CDS purB NC_002662.1 1688439 1689734 R Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase complement(1688439..1689734) Lactococcus lactis subsp. lactis Il1403 1115301 NP_267798.1 CDS aroD NC_002662.1 1689931 1690611 R catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase complement(1689931..1690611) Lactococcus lactis subsp. lactis Il1403 1115302 NP_267799.1 CDS yqjA NC_002662.1 1690874 1691077 R hypothetical protein complement(1690874..1691077) Lactococcus lactis subsp. lactis Il1403 1115303 NP_267800.1 CDS trxA NC_002662.1 1691321 1691635 R thioredoxin complement(1691321..1691635) Lactococcus lactis subsp. lactis Il1403 1115304 NP_267801.1 CDS mutS NC_002662.1 1691732 1694062 R DNA mismatch repair protein; hypothetical protein complement(1691732..1694062) Lactococcus lactis subsp. lactis Il1403 1115305 NP_267802.1 CDS yqjB NC_002662.1 1694107 1694667 R similar to YshB of Bacillus subtilis; hypothetical protein complement(1694107..1694667) Lactococcus lactis subsp. lactis Il1403 1115306 NP_267803.1 CDS trxB2 NC_002662.1 1694827 1695792 R thioredoxin, glutaredoxin, and glutathione; cofactor FAD flavoprotein; pyridine nucleotide-disulfide oxidoreductase class-II; thioredoxin reductase complement(1694827..1695792) Lactococcus lactis subsp. lactis Il1403 1115307 NP_267804.1 CDS ccpA NC_002662.1 1695930 1696928 R evidence experimental PMID:9922238; LacI-family regulators; catabolite control protein A complement(1695930..1696928) Lactococcus lactis subsp. lactis Il1403 1115308 NP_267805.1 CDS pepQ NC_002662.1 1697143 1698231 D degradation of proteins, peptides, and glycopeptides; proline dipeptidase 1697143..1698231 Lactococcus lactis subsp. lactis Il1403 1115309 NP_267806.1 CDS yqjD NC_002662.1 1698360 1700366 R hypothetical protein complement(1698360..1700366) Lactococcus lactis subsp. lactis Il1403 1115310 NP_267807.1 CDS yqjE NC_002662.1 1700514 1701668 R hypothetical protein complement(1700514..1701668) Lactococcus lactis subsp. lactis Il1403 1115311 NP_267808.1 CDS yraA NC_002662.1 1701739 1701903 R hypothetical protein complement(1701739..1701903) Lactococcus lactis subsp. lactis Il1403 1115312 NP_267809.1 CDS yraB NC_002662.1 1702302 1702688 R hypothetical protein complement(1702302..1702688) Lactococcus lactis subsp. lactis Il1403 1115313 NP_267810.1 CDS holA NC_002662.1 1702742 1703746 R required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta complement(1702742..1703746) Lactococcus lactis subsp. lactis Il1403 1115314 NP_267811.1 CDS yraD NC_002662.1 1703753 1704241 R hypothetical protein complement(1703753..1704241) Lactococcus lactis subsp. lactis Il1403 1115315 NP_267812.1 CDS ftsK NC_002662.1 1704238 1706529 R cell division protein; required for chromosome segregation and septum formation; may be involved in peptidoglycan synthesis or modification; hypothetical protein complement(1704238..1706529) Lactococcus lactis subsp. lactis Il1403 1115316 NP_267813.1 CDS yraE NC_002662.1 1706745 1707476 D hypothetical protein 1706745..1707476 Lactococcus lactis subsp. lactis Il1403 1115317 NP_267814.1 CDS yraF NC_002662.1 1707521 1707913 R hypothetical protein complement(1707521..1707913) Lactococcus lactis subsp. lactis Il1403 1115318 NP_267815.1 CDS eutD NC_002662.1 1708048 1709028 R in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase complement(1708048..1709028) Lactococcus lactis subsp. lactis Il1403 1115319 NP_267816.1 CDS udk NC_002662.1 1709245 1709865 R functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase complement(1709245..1709865) Lactococcus lactis subsp. lactis Il1403 1115320 NP_267817.1 CDS yrbA NC_002662.1 1710163 1711143 D aerobic energy metabolism; oxidoreductase 1710163..1711143 Lactococcus lactis subsp. lactis Il1403 1115321 NP_267818.1 CDS yrbB NC_002662.1 1711410 1712009 R hypothetical protein complement(1711410..1712009) Lactococcus lactis subsp. lactis Il1403 1115322 NP_267819.1 CDS yrbC NC_002662.1 1712667 1713626 D catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 1712667..1713626 Lactococcus lactis subsp. lactis Il1403 1115323 NP_267820.1 CDS yrbD NC_002662.1 1713651 1715189 R hypothetical protein complement(1713651..1715189) Lactococcus lactis subsp. lactis Il1403 1115324 NP_267821.1 CDS yrbE NC_002662.1 1715358 1715591 R hypothetical protein complement(1715358..1715591) Lactococcus lactis subsp. lactis Il1403 1115325 NP_267822.1 CDS yrbF NC_002662.1 1715613 1715882 R hypothetical protein complement(1715613..1715882) Lactococcus lactis subsp. lactis Il1403 1115326 NP_267823.1 CDS yrbG NC_002662.1 1715912 1716553 R hypothetical protein complement(1715912..1716553) Lactococcus lactis subsp. lactis Il1403 1115327 NP_267824.1 CDS yrbH NC_002662.1 1716550 1716855 R hypothetical protein complement(1716550..1716855) Lactococcus lactis subsp. lactis Il1403 1115328 NP_267825.1 CDS yrbI NC_002662.1 1717007 1717840 R similar to positive regulator GadR of Lactococcus lactis; transcriptional regulator complement(1717007..1717840) Lactococcus lactis subsp. lactis Il1403 1115329 NP_267826.1 CDS pip NC_002662.1 1718713 1721418 R evidence experimental PMID:8366036; transmembrane protein; phage infection protein complement(1718713..1721418) Lactococcus lactis subsp. lactis Il1403 1115331 NP_267827.1 CDS arb NC_002662.1 1721677 1723110 R required for arbutin uptake and metabolism; 6-phospho-beta-glucosidase complement(1721677..1723110) Lactococcus lactis subsp. lactis Il1403 1115332 NP_267828.1 CDS yrcB NC_002662.1 1723233 1723499 R similar to YtjA of Bacillus subtilis; hypothetical protein complement(1723233..1723499) Lactococcus lactis subsp. lactis Il1403 1115333 NP_267829.1 CDS dxsB NC_002662.1 1723616 1725358 R catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase complement(1723616..1725358) Lactococcus lactis subsp. lactis Il1403 1115334 NP_267830.1 CDS kinF NC_002662.1 1725506 1726876 R two-component systems; sensor protein kinase complement(1725506..1726876) Lactococcus lactis subsp. lactis Il1403 1115335 NP_267831.1 CDS llrF NC_002662.1 1726969 1727646 R evidence experimental PMID:10708382; two-component systems; involved in oxidative stress resistance development; two-component system regulator complement(1726969..1727646) Lactococcus lactis subsp. lactis Il1403 1115336 NP_267832.1 CDS rliA NC_002662.1 1727815 1728789 R LacI-family regulators; transcriptional regulator complement(1727815..1728789) Lactococcus lactis subsp. lactis Il1403 1115337 NP_267833.1 CDS mapA NC_002662.1 1728942 1731197 R central intermediary metabolism; maltose phosphorylase complement(1728942..1731197) Lactococcus lactis subsp. lactis Il1403 1115338 NP_267834.1 CDS agl NC_002662.1 1731220 1732857 R degradation of polysaccharides; alpha-glucosidase complement(1731220..1732857) Lactococcus lactis subsp. lactis Il1403 1115339 NP_267835.1 CDS amyY NC_002662.1 1732900 1734474 R degradation of polysaccharides; alpha-amylase complement(1732900..1734474) Lactococcus lactis subsp. lactis Il1403 1115340 NP_267836.1 CDS maa NC_002662.1 1734464 1735075 R energy metabolism, sugars; maltose O-acetyltransferase complement(1734464..1735075) Lactococcus lactis subsp. lactis Il1403 1115341 NP_267837.1 CDS dexA NC_002662.1 1735096 1736721 R degradation of polysaccharides; oligo-1,6-glucosidase complement(1735096..1736721) Lactococcus lactis subsp. lactis Il1403 1115342 NP_267838.1 CDS dexC NC_002662.1 1736928 1738682 R degradation of polysaccharides; neopullulanase complement(1736928..1738682) Lactococcus lactis subsp. lactis Il1403 1115343 NP_267839.1 CDS malE NC_002662.1 1739050 1740282 D transport and binding protein, carbohydrates; organic alcohols and acids; maltose ABC transporter substrate binding protein 1739050..1740282 Lactococcus lactis subsp. lactis Il1403 1115344 NP_267840.1 CDS malF NC_002662.1 1740354 1741712 D transport and binding protein, carbohydrates; organic alcohols and acids; maltose ABC transporter permease 1740354..1741712 Lactococcus lactis subsp. lactis Il1403 1115345 NP_267841.1 CDS malG NC_002662.1 1741716 1742573 D transport and binding protein, carbohydrates; organic alcohols and acids; maltose ABC transporter permease 1741716..1742573 Lactococcus lactis subsp. lactis Il1403 1115346 NP_267842.1 CDS yreA NC_002662.1 1742733 1743728 D hypothetical protein 1742733..1743728 Lactococcus lactis subsp. lactis Il1403 1115347 NP_267843.1 CDS yreB NC_002662.1 1743734 1744678 D hypothetical protein 1743734..1744678 Lactococcus lactis subsp. lactis Il1403 1115348 NP_267844.1 CDS yreC NC_002662.1 1744680 1745237 D hypothetical protein 1744680..1745237 Lactococcus lactis subsp. lactis Il1403 1115349 NP_267845.1 CDS yreD NC_002662.1 1745270 1745806 R hypothetical protein complement(1745270..1745806) Lactococcus lactis subsp. lactis Il1403 1115350 NP_835325.1 CDS L200065 NC_002662.1 1745916 1746191 R hypothetical protein complement(1745916..1746191) Lactococcus lactis subsp. lactis Il1403 1115351 NP_267846.1 CDS yreE NC_002662.1 1746412 1747098 D hypothetical protein 1746412..1747098 Lactococcus lactis subsp. lactis Il1403 1115352 NP_267847.1 CDS tra981I NC_002662.1 1747150 1747989 R evidence experimental PMID:8389385; transposon related function; related to a family of IS elements that includes IS2, IS3, IS150, IS600, IS629, IS861, IS904 and ISL1; transposase of IS981I complement(1747150..1747989) Lactococcus lactis subsp. lactis Il1403 1115353 NP_267848.1 CDS yrdA NC_002662.1 1748001 1748261 R transposon related function; orf1 of IS981; transposase complement(1748001..1748261) Lactococcus lactis subsp. lactis Il1403 1115354 NP_267849.1 CDS yrdB NC_002662.1 1748664 1749278 D hypothetical protein 1748664..1749278 Lactococcus lactis subsp. lactis Il1403 1115355 NP_835326.1 CDS yreF NC_002662.1 1749401 1750033 D similar to internalin; hypothetical protein 1749401..1750033 Lactococcus lactis subsp. lactis Il1403 1115356 NP_267850.1 CDS yrfA NC_002662.1 1750127 1750429 D ArsR family of transcription regulators; transcriptional regulator 1750127..1750429 Lactococcus lactis subsp. lactis Il1403 1115357 NP_267851.1 CDS yrfB NC_002662.1 1750521 1751696 D aerobic energy metabolism; NADH-dependent oxidoreductase 1750521..1751696 Lactococcus lactis subsp. lactis Il1403 1115358 NP_267852.1 CDS arcC3 NC_002662.1 1752008 1752955 R catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase complement(1752008..1752955) Lactococcus lactis subsp. lactis Il1403 1115359 NP_267853.1 CDS yrfC NC_002662.1 1752980 1754080 R catalyzes the formation of carbamoylputrescine from agmatine in the arginine decarboxylase pathway of putrescine biosynthesis; agmatine deiminase complement(1752980..1754080) Lactococcus lactis subsp. lactis Il1403 1115360 NP_267854.1 CDS tra983G NC_002662.1 1754225 1755172 D transposon related function; belongs to the IS30 family of transposase; transposase of IS983G 1754225..1755172 Lactococcus lactis subsp. lactis Il1403 1115361 NP_267855.1 CDS yrfD NC_002662.1 1755132 1756532 R transport and binding protein; amino acids, peptides and amines; amino acid antiporter complement(1755132..1756532) Lactococcus lactis subsp. lactis Il1403 1115362 NP_267856.1 CDS otcA NC_002662.1 1756548 1757570 R catalyzes the formation of putrescine from carbamoyl-putrescine during agmatine degradation; putrescine carbamoyltransferase complement(1756548..1757570) Lactococcus lactis subsp. lactis Il1403 1115363 NP_267857.1 CDS llrH NC_002662.1 1757804 1758790 R two-component systems; two-component system regulator complement(1757804..1758790) Lactococcus lactis subsp. lactis Il1403 1115364 NP_267858.1 CDS yrfE NC_002662.1 1758958 1760361 R LytR family; probably a signal transducer for the regulator LrrH; transcriptional regulator complement(1758958..1760361) Lactococcus lactis subsp. lactis Il1403 1115365 NP_267859.1 CDS cmk NC_002662.1 1760439 1761101 R Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase complement(1760439..1761101) Lactococcus lactis subsp. lactis Il1403 1115366 NP_267860.1 CDS yrgA NC_002662.1 1761183 1761701 R hypothetical protein complement(1761183..1761701) Lactococcus lactis subsp. lactis Il1403 1115367 NP_267861.1 CDS fer NC_002662.1 1761748 1761951 D energy metabolism; electron transport; iron sulfur protein that transfers electrons in a variety of metabolic reactions; ferredoxin 1761748..1761951 Lactococcus lactis subsp. lactis Il1403 1115368 NP_267862.1 CDS ptnAB NC_002662.1 1762221 1763210 D transport and binding protein; PTS system; PTS system mannose-specific transporter subunit IIAB 1762221..1763210 Lactococcus lactis subsp. lactis Il1403 1115369 NP_267863.1 CDS ptnC NC_002662.1 1763289 1764101 D transport and binding protein; PTS system; PTS system mannose-specific transporter subunit IIC 1763289..1764101 Lactococcus lactis subsp. lactis Il1403 1115370 NP_267864.1 CDS ptnD NC_002662.1 1764120 1765043 D transport and binding protein; PTS system; PTS system mannose-specific transporter subunit IID 1764120..1765043 Lactococcus lactis subsp. lactis Il1403 1115371 NP_267865.1 CDS yrgE NC_002662.1 1765185 1765568 D hypothetical protein 1765185..1765568 Lactococcus lactis subsp. lactis Il1403 1115372 NP_267866.1 CDS yrgF NC_002662.1 1765593 1766288 R hypothetical protein complement(1765593..1766288) Lactococcus lactis subsp. lactis Il1403 1115373 NP_267867.1 CDS yrgG NC_002662.1 1766438 1766809 D hypothetical protein 1766438..1766809 Lactococcus lactis subsp. lactis Il1403 1115374 NP_267868.1 CDS serS NC_002662.1 1767193 1768464 D catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 1767193..1768464 Lactococcus lactis subsp. lactis Il1403 1115375 NP_267869.1 CDS yrgH NC_002662.1 1768653 1769627 D hypothetical protein 1768653..1769627 Lactococcus lactis subsp. lactis Il1403 1115376 NP_267870.1 CDS yrgI NC_002662.1 1769649 1770218 D hypothetical protein 1769649..1770218 Lactococcus lactis subsp. lactis Il1403 1115377 NP_267871.1 CDS phoU NC_002662.1 1770313 1770966 R general regulatory function; phosphate transport system regulator complement(1770313..1770966) Lactococcus lactis subsp. lactis Il1403 1115378 NP_267872.1 CDS pstA NC_002662.1 1771129 1771890 R ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein complement(1771129..1771890) Lactococcus lactis subsp. lactis Il1403 1115379 NP_267873.1 CDS pstB NC_002662.1 1772056 1772865 R ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein complement(1772056..1772865) Lactococcus lactis subsp. lactis Il1403 1115380 NP_267874.1 CDS pstC NC_002662.1 1772899 1773792 R transport and binding protein, anions; phosphate ABC transporter permease complement(1772899..1773792) Lactococcus lactis subsp. lactis Il1403 1115381 NP_267875.1 CDS pstD NC_002662.1 1773792 1774715 R transport and binding protein, anions; phosphate ABC transporter permease complement(1773792..1774715) Lactococcus lactis subsp. lactis Il1403 1115382 NP_267876.1 CDS pstE NC_002662.1 1774836 1775687 R transport and binding protein, anions; identical to lipoprotein Nlp1 of Lactococcus lactis; phosphate ABC transporter substrate-binding protein complement(1774836..1775687) Lactococcus lactis subsp. lactis Il1403 1115383 NP_267877.1 CDS pstF NC_002662.1 1776034 1776930 R transport and binding protein, anions; similar to lipoprotein Nlp1 from Lactococcus lactis; phosphate ABC transporter substrate-binding protein complement(1776034..1776930) Lactococcus lactis subsp. lactis Il1403 1115384 NP_267878.1 CDS smpB NC_002662.1 1777208 1777675 R binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein complement(1777208..1777675) Lactococcus lactis subsp. lactis Il1403 1115385 NP_267879.1 CDS yrhH NC_002662.1 1777707 1778282 R hypothetical protein complement(1777707..1778282) Lactococcus lactis subsp. lactis Il1403 1115386 NP_267880.1 CDS alaS NC_002662.1 1778369 1780987 R Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase complement(1778369..1780987) Lactococcus lactis subsp. lactis Il1403 1115387 NP_267881.1 CDS pmpA NC_002662.1 1781253 1782179 R maturation protein complement(1781253..1782179) Lactococcus lactis subsp. lactis Il1403 1115388 NP_267882.1 CDS yriA NC_002662.1 1782333 1783016 R SAM-dependent methyltransferase, evidenced by COGnitor; hypothetical protein complement(1782333..1783016) Lactococcus lactis subsp. lactis Il1403 1115389 NP_267883.1 CDS pepF NC_002662.1 1783019 1784824 R evidence experimental PMID:7798200; degradation of proteins, peptides, and glycopeptides; hydrolyzes peptides containing between 7 and 17 amino acids with a rather wide specificity; peptidase family M3 (zinc metalloprotease); oligoendopeptidase F complement(1783019..1784824) Lactococcus lactis subsp. lactis Il1403 1115390 NP_267884.1 CDS coiA NC_002662.1 1784887 1785876 R competence protein; transformation; similar to CoiA protein in Streptococcus pneumoniae needed for competence development; CoiA complement(1784887..1785876) Lactococcus lactis subsp. lactis Il1403 1115391 NP_267885.1 CDS yriB NC_002662.1 1785950 1787035 R hypothetical protein complement(1785950..1787035) Lactococcus lactis subsp. lactis Il1403 1115392 NP_267886.1 CDS yriC NC_002662.1 1787197 1788045 R hypothetical protein complement(1787197..1788045) Lactococcus lactis subsp. lactis Il1403 1115393 NP_267887.1 CDS yriD NC_002662.1 1788237 1789658 R xanthine/uracil/vitamin C permease complement(1788237..1789658) Lactococcus lactis subsp. lactis Il1403 1115394 NP_267888.1 CDS yrjA NC_002662.1 1789965 1790801 D hypothetical protein 1789965..1790801 Lactococcus lactis subsp. lactis Il1403 1115395 NP_267889.1 CDS yrjB NC_002662.1 1790982 1791752 D aerobic energy metabolism; similar to different oxido-reductases; oxidoreductase 1790982..1791752 Lactococcus lactis subsp. lactis Il1403 1115396 NP_267890.1 CDS yrjC NC_002662.1 1791762 1793234 D aerobic energy metabolism; similar to several iron-binding oxidase subunit proteins; iron-binding oxidase subunit 1791762..1793234 Lactococcus lactis subsp. lactis Il1403 1115397 NP_267891.1 CDS yrjD NC_002662.1 1793237 1793920 D hypothetical protein 1793237..1793920 Lactococcus lactis subsp. lactis Il1403 1115398 NP_267892.1 CDS yrjE NC_002662.1 1793995 1794708 R transport and binding protein; similar to several permeases; transport permease complement(1793995..1794708) Lactococcus lactis subsp. lactis Il1403 1115399 NP_267893.1 CDS yrjF NC_002662.1 1794821 1795735 R hypothetical protein complement(1794821..1795735) Lactococcus lactis subsp. lactis Il1403 1115400 NP_267894.1 CDS yrjG NC_002662.1 1795892 1796404 R hypothetical protein complement(1795892..1796404) Lactococcus lactis subsp. lactis Il1403 1115401 NP_267895.1 CDS rpsT NC_002662.1 1796737 1796970 D binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 1796737..1796970 Lactococcus lactis subsp. lactis Il1403 1115402 NP_267896.1 CDS recD NC_002662.1 1797064 1799568 R exodeoxyribonuclease V subunit alpha complement(1797064..1799568) Lactococcus lactis subsp. lactis Il1403 1115403 NP_267897.1 CDS yrjI NC_002662.1 1799565 1800158 R glycolysis; similar to phosphoglycerate mutases or 6-phosphofructo-2-kinases; phosphoglycerate mutase complement(1799565..1800158) Lactococcus lactis subsp. lactis Il1403 1115404 NP_267898.1 CDS pheA NC_002662.1 1800161 1801000 R catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; prephenate dehydratase complement(1800161..1801000) Lactococcus lactis subsp. lactis Il1403 1115405 NP_267899.1 CDS aroK NC_002662.1 1801002 1801490 R evidence experimental PMID:7823907; aromatic amino-acid family; shikimate kinase complement(1801002..1801490) Lactococcus lactis subsp. lactis Il1403 1115406 NP_267900.1 CDS aroA NC_002662.1 1801514 1802806 R catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase complement(1801514..1802806) Lactococcus lactis subsp. lactis Il1403 1115407 NP_267901.1 CDS tyrA NC_002662.1 1802927 1803991 R catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate; prephenate dehydrogenase complement(1802927..1803991) Lactococcus lactis subsp. lactis Il1403 1115408 NP_267902.1 CDS kinG NC_002662.1 1803994 1804869 R two-component systems; sensor protein kinase complement(1803994..1804869) Lactococcus lactis subsp. lactis Il1403 1115409 NP_267903.1 CDS llrG NC_002662.1 1804856 1805527 R two-component systems; two-component system regulator complement(1804856..1805527) Lactococcus lactis subsp. lactis Il1403 1115410 NP_267904.1 CDS ysaA NC_002662.1 1805530 1806594 R hypothetical protein complement(1805530..1806594) Lactococcus lactis subsp. lactis Il1403 1115411 NP_267905.1 CDS ysaB NC_002662.1 1806775 1808778 R transport and binding protein; probably the same function as YtsD of Bacillus subtilis; ABC transporter permease and substrate binding protein complement(1806775..1808778) Lactococcus lactis subsp. lactis Il1403 1115412 NP_267906.1 CDS ysaC NC_002662.1 1808771 1809550 R transport and binding protein; ABC transporter ATP-binding protein complement(1808771..1809550) Lactococcus lactis subsp. lactis Il1403 1115413 NP_267907.1 CDS ysaD NC_002662.1 1809739 1810098 R hypothetical protein complement(1809739..1810098) Lactococcus lactis subsp. lactis Il1403 1115414 NP_267908.1 CDS aroC NC_002662.1 1810217 1811383 R catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase complement(1810217..1811383) Lactococcus lactis subsp. lactis Il1403 1115415 NP_267909.1 CDS ysbA NC_002662.1 1811414 1812010 R hypothetical protein complement(1811414..1812010) Lactococcus lactis subsp. lactis Il1403 1115416 NP_267910.1 CDS ysbB NC_002662.1 1812015 1812614 R similar to YktB of Bacillus subtilis; hypothetical protein complement(1812015..1812614) Lactococcus lactis subsp. lactis Il1403 1115417 NP_267911.1 CDS ysbC NC_002662.1 1812726 1813649 R hypothetical protein complement(1812726..1813649) Lactococcus lactis subsp. lactis Il1403 1115418 NP_267912.1 CDS aroB NC_002662.1 1813760 1814830 R catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase complement(1813760..1814830) Lactococcus lactis subsp. lactis Il1403 1115419 NP_267913.1 CDS aroE NC_002662.1 1814827 1815687 R AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase complement(1814827..1815687) Lactococcus lactis subsp. lactis Il1403 1115420 NP_267914.1 CDS ysbD NC_002662.1 1815855 1816511 R hypothetical protein complement(1815855..1816511) Lactococcus lactis subsp. lactis Il1403 1115421 NP_267915.1 CDS glnP NC_002662.1 1816892 1819036 D transport and binding protein; amino acids, peptides and amines; N-terimal 500 aa is substrate binding, and the C-terminal is permease domain; glutamine ABC transporter permease and substrate binding protein 1816892..1819036 Lactococcus lactis subsp. lactis Il1403 1115422 NP_267916.1 CDS glnQ NC_002662.1 1819052 1819795 D transport and binding protein; amino acids, peptides and amines; glutamine ABC transporter ATP-binding protein 1819052..1819795 Lactococcus lactis subsp. lactis Il1403 1115423 NP_267917.1 CDS yscA NC_002662.1 1819904 1821823 R hypothetical protein complement(1819904..1821823) Lactococcus lactis subsp. lactis Il1403 1115424 NP_267918.1 CDS yscB NC_002662.1 1821845 1822486 R hypothetical protein complement(1821845..1822486) Lactococcus lactis subsp. lactis Il1403 1115425 NP_267919.1 CDS atpC NC_002662.1 1822602 1823027 R part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon complement(1822602..1823027) Lactococcus lactis subsp. lactis Il1403 1115426 NP_267920.1 CDS atpD NC_002662.1 1823212 1824621 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta complement(1823212..1824621) Lactococcus lactis subsp. lactis Il1403 1115427 NP_267921.1 CDS atpG NC_002662.1 1824754 1825623 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma complement(1824754..1825623) Lactococcus lactis subsp. lactis Il1403 1115428 NP_267922.1 CDS atpA NC_002662.1 1825639 1827141 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha complement(1825639..1827141) Lactococcus lactis subsp. lactis Il1403 1115429 NP_267923.1 CDS atpH NC_002662.1 1827328 1827855 R Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta complement(1827328..1827855) Lactococcus lactis subsp. lactis Il1403 1115430 NP_267924.1 CDS atpF NC_002662.1 1827857 1828363 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B complement(1827857..1828363) Lactococcus lactis subsp. lactis Il1403 1115431 NP_267925.2 CDS atpB NC_002662.1 1828378 1829091 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A complement(1828378..1829091) Lactococcus lactis subsp. lactis Il1403 1115432 NP_267926.1 CDS atpE NC_002662.1 1829136 1829351 R produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C complement(1829136..1829351) Lactococcus lactis subsp. lactis Il1403 1115433 NP_267928.1 CDS yscE NC_002662.1 1829535 1830311 R fatty acid and phospholipid metabolism; lipase complement(1829535..1830311) Lactococcus lactis subsp. lactis Il1403 1115435 NP_267929.1 CDS comEC NC_002662.1 1830596 1832806 R competence protein; transformation; required for internalisation of transforming DNA, but is dispensable for DNA binding.; hypothetical protein complement(1830596..1832806) Lactococcus lactis subsp. lactis Il1403 1115436 NP_267930.1 CDS comEA NC_002662.1 1832787 1833434 R competence protein; DNA receptor during transformation; membrane protein; hypothetical protein complement(1832787..1833434) Lactococcus lactis subsp. lactis Il1403 1115437 NP_267931.1 CDS ysdA NC_002662.1 1833494 1834855 R transport and binding protein; ABC transporter permease complement(1833494..1834855) Lactococcus lactis subsp. lactis Il1403 1115438 NP_267932.1 CDS ysdB NC_002662.1 1834852 1835784 R transport and binding protein; ABC transporter ATP-binding protein complement(1834852..1835784) Lactococcus lactis subsp. lactis Il1403 1115439 NP_267933.1 CDS ysdC NC_002662.1 1835889 1836287 R hypothetical protein complement(1835889..1836287) Lactococcus lactis subsp. lactis Il1403 1115440 NP_267934.1 CDS bar NC_002662.1 1836391 1836954 R drug and analog sensitivity; acyltransferase complement(1836391..1836954) Lactococcus lactis subsp. lactis Il1403 1115441 NP_267935.1 CDS ysdE NC_002662.1 1837127 1838305 R transort and binding protein, cations; cation transporter complement(1837127..1838305) Lactococcus lactis subsp. lactis Il1403 1115442 NP_267936.1 CDS tenA NC_002662.1 1838686 1839342 R transcription regulator; in Bacillus subtilis production of several extracellular degradative enzymes at the transcription level, probably by interfering with DegS and DegU, which are required from this effect; TenA protein complement(1838686..1839342) Lactococcus lactis subsp. lactis Il1403 1115443 NP_835327.1 CDS L200067 NC_002662.1 1839378 1839683 R hypothetical protein complement(1839378..1839683) Lactococcus lactis subsp. lactis Il1403 1115444 NP_267937.1 CDS birA1 NC_002662.1 1839700 1840671 R bifunctional protein; biotin-(acetyl-CoA carboxylase) ligase; biotin operon repressor complement(1839700..1840671) Lactococcus lactis subsp. lactis Il1403 1115445 NP_267938.1 CDS yseA NC_002662.1 1840677 1841246 R hypothetical protein complement(1840677..1841246) Lactococcus lactis subsp. lactis Il1403 1115446 NP_267939.1 CDS yseB NC_002662.1 1841391 1842632 D hypothetical protein 1841391..1842632 Lactococcus lactis subsp. lactis Il1403 1115447 NP_267940.1 CDS fadA NC_002662.1 1842622 1843770 D fatty acid and phospholipid metabolism; acetyl coenzyme A acetyltransferase 1842622..1843770 Lactococcus lactis subsp. lactis Il1403 1115448 NP_267941.1 CDS yseC NC_002662.1 1843755 1844117 D hypothetical protein 1843755..1844117 Lactococcus lactis subsp. lactis Il1403 1115449 NP_267942.1 CDS yseD NC_002662.1 1844092 1844385 D hypothetical protein 1844092..1844385 Lactococcus lactis subsp. lactis Il1403 1115450 NP_267943.1 CDS fabG2 NC_002662.1 1844382 1845128 D fatty acid and phospholipid metabolism; 3-oxoacyl-ACP reductase 1844382..1845128 Lactococcus lactis subsp. lactis Il1403 1115451 NP_267944.1 CDS yseE NC_002662.1 1845151 1845996 D energy metabolism; fermentation; similar to 2-nitropropane dioxygenase; 2-nitropropane dioxygenase 1845151..1845996 Lactococcus lactis subsp. lactis Il1403 1115452 NP_267945.1 CDS yseF NC_002662.1 1846137 1847549 R hypothetical protein complement(1846137..1847549) Lactococcus lactis subsp. lactis Il1403 1115453 NP_267946.2 CDS nifU NC_002662.1 1847783 1848241 R energy metabolism; electron transport; involved in Fe-S cluster formation; hypothetical protein complement(1847783..1848241) Lactococcus lactis subsp. lactis Il1403 1115454 NP_267947.1 CDS yseH NC_002662.1 1848357 1848839 R hypothetical protein complement(1848357..1848839) Lactococcus lactis subsp. lactis Il1403 1115455 NP_267948.1 CDS yseI NC_002662.1 1848841 1850058 R selenocysteine lyase, evidenced by COGnitor; similar to YurW of Bacillus subtilis; hypothetical protein complement(1848841..1850058) Lactococcus lactis subsp. lactis Il1403 1115456 NP_267949.1 CDS ysfA NC_002662.1 1850058 1851314 R hypothetical protein complement(1850058..1851314) Lactococcus lactis subsp. lactis Il1403 1115457 NP_267950.1 CDS ysfB NC_002662.1 1851452 1852222 R transport and binding protein; ABC transporter ATP-binding protein complement(1851452..1852222) Lactococcus lactis subsp. lactis Il1403 1115458 NP_267951.1 CDS ysfC NC_002662.1 1852397 1853728 R surface polysaccharides, lipopolysaccharides and antigens; similar to TagO of Bacillus subtilis involved in teichoic acid linkage unit synthesis; polysacharide biosynthesis protein complement(1852397..1853728) Lactococcus lactis subsp. lactis Il1403 1115459 NP_267952.1 CDS ysfD NC_002662.1 1853731 1854432 R similar to MecA protein from Bacillus; regulatory protein complement(1853731..1854432) Lactococcus lactis subsp. lactis Il1403 1115460 NP_267953.1 CDS gltQ NC_002662.1 1854562 1855296 R transport and binding protein; amino acids, peptides and amines; glutamate ABC transporter ATP-binding protein complement(1854562..1855296) Lactococcus lactis subsp. lactis Il1403 1115461 NP_267954.1 CDS gltP NC_002662.1 1855296 1855982 R transport and binding protein; amino acids, peptides and amines; glutamate ABC transporter permease complement(1855296..1855982) Lactococcus lactis subsp. lactis Il1403 1115462 NP_267955.1 CDS ysfG NC_002662.1 1856130 1857038 R similar to YtlR of Bacillus subtilis; transcriptional regulator complement(1856130..1857038) Lactococcus lactis subsp. lactis Il1403 1115463 NP_267956.1 CDS rpoC NC_002662.1 1857183 1860779 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' complement(1857183..1860779) Lactococcus lactis subsp. lactis Il1403 1115464 NP_267957.1 CDS rpoB NC_002662.1 1860915 1864505 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta complement(1860915..1864505) Lactococcus lactis subsp. lactis Il1403 1115465 NP_267958.1 CDS codZ NC_002662.1 1864771 1865379 R CodY family of transcription regulators; transcriptional regulator complement(1864771..1865379) Lactococcus lactis subsp. lactis Il1403 1115466 NP_267959.1 CDS ysgA NC_002662.1 1865612 1866286 D similar to EpsR of the epsRXABCDEFGHIJKL operon of Lactococcus lactis plasmid pNZ4000; transcriptional regulator 1865612..1866286 Lactococcus lactis subsp. lactis Il1403 1115467 NP_267960.1 CDS pepO NC_002662.1 1866399 1868282 D evidence experimental PMID:8244921; degradation of proteins, peptides, and glycopeptides; neutral endopeptidase 1866399..1868282 Lactococcus lactis subsp. lactis Il1403 1115468 NP_267961.1 CDS ysgB NC_002662.1 1868336 1868641 R hypothetical protein complement(1868336..1868641) Lactococcus lactis subsp. lactis Il1403 1115469 NP_267962.1 CDS ysgC NC_002662.1 1868710 1870383 R hypothetical protein complement(1868710..1870383) Lactococcus lactis subsp. lactis Il1403 1115470 NP_267963.1 CDS murE NC_002662.1 1870593 1872044 D involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 1870593..1872044 Lactococcus lactis subsp. lactis Il1403 1115471 NP_267964.1 CDS adhA NC_002662.1 1872404 1873426 R similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase complement(1872404..1873426) Lactococcus lactis subsp. lactis Il1403 1115472 NP_267965.1 CDS recQ NC_002662.1 1873622 1875400 D ATP-dependent DNA helicase; transformation; probably a part of the competence regulon; ATP-dependent DNA helicase RecQ 1873622..1875400 Lactococcus lactis subsp. lactis Il1403 1115473 NP_267966.2 CDS yshA NC_002662.1 1875436 1876962 R transport and binding protein; amino acids, peptides and amines; similar to many amino acid permeases; amino acid permease complement(1875436..1876962) Lactococcus lactis subsp. lactis Il1403 1115474 NP_267967.1 CDS pepT NC_002662.1 1877242 1878483 R catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T complement(1877242..1878483) Lactococcus lactis subsp. lactis Il1403 1115475 NP_267968.1 CDS yshB NC_002662.1 1878512 1879309 R hypothetical protein complement(1878512..1879309) Lactococcus lactis subsp. lactis Il1403 1115476 NP_267969.1 CDS yshC NC_002662.1 1879309 1880253 R catalyzes the hydrolysis of pyrophosphate to phosphate; manganese-dependent inorganic pyrophosphatase complement(1879309..1880253) Lactococcus lactis subsp. lactis Il1403 1115477 NP_267970.1 CDS pflA NC_002662.1 1880457 1881251 R pyruvate-formate lyase activating enzyme complement(1880457..1881251) Lactococcus lactis subsp. lactis Il1403 1115478 NP_267971.1 CDS ysiA NC_002662.1 1881457 1882806 R transport and binding protein; transporter complement(1881457..1882806) Lactococcus lactis subsp. lactis Il1403 1115479 NP_267972.1 CDS ysiB NC_002662.1 1882927 1884042 R transport and binding protein; permease complement(1882927..1884042) Lactococcus lactis subsp. lactis Il1403 1115480 NP_267973.1 CDS ysiC NC_002662.1 1884191 1884634 D probably acyltransferase, evidenced by COGnitor; hypothetical protein 1884191..1884634 Lactococcus lactis subsp. lactis Il1403 1115481 NP_267974.1 CDS ysiD NC_002662.1 1884712 1885293 R similar to HI0220.2 of Haemophilus influenzae Rd; hypothetical protein complement(1884712..1885293) Lactococcus lactis subsp. lactis Il1403 1115482 NP_267975.1 CDS uvrA NC_002662.1 1885624 1888446 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A complement(1885624..1888446) Lactococcus lactis subsp. lactis Il1403 1115483 NP_267976.1 CDS ysiE NC_002662.1 1888525 1889163 R hypothetical protein complement(1888525..1889163) Lactococcus lactis subsp. lactis Il1403 1115484 NP_267977.1 CDS cobC NC_002662.1 1889232 1889756 D riboflavin and cobalamin; similar to phosphoglycerate mutases; alpha-ribazole-5'-phosphate phosphatase 1889232..1889756 Lactococcus lactis subsp. lactis Il1403 1115485 NP_267978.1 CDS ysiG NC_002662.1 1889753 1890067 D similar to YazA of Bacillus subtilis; hypothetical protein 1889753..1890067 Lactococcus lactis subsp. lactis Il1403 1115486 NP_267979.1 CDS ysjA NC_002662.1 1890081 1891430 R transport and binding protein; amino acids, peptides and amines; similar to many amino acid permeases; amino acid permease complement(1890081..1891430) Lactococcus lactis subsp. lactis Il1403 1115487 NP_267980.1 CDS ysjB NC_002662.1 1891913 1892830 R aerobic energy metabolism; oxidoreductase complement(1891913..1892830) Lactococcus lactis subsp. lactis Il1403 1115488 NP_267981.1 CDS ysjC NC_002662.1 1892862 1893497 R similar to YloS protein of Bacillus subtilis; hypothetical protein complement(1892862..1893497) Lactococcus lactis subsp. lactis Il1403 1115489 NP_267982.1 CDS ysjD NC_002662.1 1893494 1893841 R hypothetical protein complement(1893494..1893841) Lactococcus lactis subsp. lactis Il1403 1115490 NP_267983.1 CDS ysjE NC_002662.1 1893866 1894297 R hypothetical protein complement(1893866..1894297) Lactococcus lactis subsp. lactis Il1403 1115491 NP_267984.1 CDS ysjF NC_002662.1 1894511 1895050 D hypothetical protein 1894511..1895050 Lactococcus lactis subsp. lactis Il1403 1115492 NP_267985.1 CDS asnC NC_002662.1 1895088 1896431 R catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase complement(1895088..1896431) Lactococcus lactis subsp. lactis Il1403 1115493 NP_267986.1 CDS ysjG NC_002662.1 1896479 1896790 R hypothetical protein complement(1896479..1896790) Lactococcus lactis subsp. lactis Il1403 1115494 NP_267987.1 CDS aspB NC_002662.1 1896787 1897968 R catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase complement(1896787..1897968) Lactococcus lactis subsp. lactis Il1403 1115495 NP_267988.1 CDS ysjH NC_002662.1 1897965 1898408 R hypothetical protein complement(1897965..1898408) Lactococcus lactis subsp. lactis Il1403 1115496 NP_267989.1 CDS dinG NC_002662.1 1898543 1900927 R ATP-dependent helicase; DNA replication, restriction, modification, recombination, and repair; helicase involved in DNA repair and perhaps also replication; DinG complement(1898543..1900927) Lactococcus lactis subsp. lactis Il1403 1115497 NP_267990.1 CDS ytaA NC_002662.1 1901147 1901584 D hypothetical protein 1901147..1901584 Lactococcus lactis subsp. lactis Il1403 1115498 NP_267991.1 CDS ytaB NC_002662.1 1901638 1902930 R transport and binding protein; similar to CBS domain-containing proteins; hypothetical protein complement(1901638..1902930) Lactococcus lactis subsp. lactis Il1403 1115499 NP_267992.1 CDS pacB NC_002662.1 1903070 1904071 R drug and analog sensitivity; penicillin acylase complement(1903070..1904071) Lactococcus lactis subsp. lactis Il1403 1115500 NP_267993.1 CDS ytaD NC_002662.1 1904143 1904889 R translation; protein modification; tyrosine phosphatase complement(1904143..1904889) Lactococcus lactis subsp. lactis Il1403 1115501 NP_267994.1 CDS oppA NC_002662.1 1905092 1906894 R evidence experimental PMID:8586224; transport and binding protein; amino acids, peptides and amines; oligopeptide ABC transporter substrate binding protein complement(1905092..1906894) Lactococcus lactis subsp. lactis Il1403 1115502 NP_267995.1 CDS oppC NC_002662.1 1906999 1907883 R evidence experimental PMID:8586224; transport and binding protein; amino acids, peptides and amines; oligopeptide ABC transporter permease complement(1906999..1907883) Lactococcus lactis subsp. lactis Il1403 1115503 NP_267996.1 CDS oppB NC_002662.1 1907893 1908852 R evidence experimental PMID:8586224; transport and binding protein; amino acids, peptides and amines; oligopeptide ABC transporter permease complement(1907893..1908852) Lactococcus lactis subsp. lactis Il1403 1115504 NP_267997.1 CDS oppF NC_002662.1 1908833 1909792 R evidence experimental PMID:8586224; transport and binding protein; amino acids, peptides and amines; oligopeptide ABC transporter ATP binding protein complement(1908833..1909792) Lactococcus lactis subsp. lactis Il1403 1115505 NP_267998.1 CDS oppD NC_002662.1 1909789 1910805 R evidence experimental PMID:8586224; transport and binding protein; amino acids, peptides and amines; oligopeptide ABC transporter ATP binding protein complement(1909789..1910805) Lactococcus lactis subsp. lactis Il1403 1115506 NP_267999.1 CDS rplT NC_002662.1 1911031 1911390 R binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 complement(1911031..1911390) Lactococcus lactis subsp. lactis Il1403 1115507 NP_268000.1 CDS rpmI NC_002662.1 1911552 1911752 R ribosomal proteins; synthesis and modification; L35P family of ribosomal proteins; 50S ribosomal protein L35 complement(1911552..1911752) Lactococcus lactis subsp. lactis Il1403 1115508 NP_268001.1 CDS infC NC_002662.1 1911881 1912375 R IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 complement(1911881..1912375) Lactococcus lactis subsp. lactis Il1403 1115509 NP_268002.1 CDS ytbA NC_002662.1 1912985 1913533 D hypothetical protein 1912985..1913533 Lactococcus lactis subsp. lactis Il1403 1115510 NP_268003.1 CDS ytbB NC_002662.1 1913544 1914248 R hypothetical protein complement(1913544..1914248) Lactococcus lactis subsp. lactis Il1403 1115511 NP_268004.1 CDS gidA NC_002662.1 1914418 1916295 R GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA complement(1914418..1916295) Lactococcus lactis subsp. lactis Il1403 1115512 NP_268005.1 CDS ytbC NC_002662.1 1916668 1917243 R hypothetical protein complement(1916668..1917243) Lactococcus lactis subsp. lactis Il1403 1115513 NP_268006.1 CDS ytbD NC_002662.1 1917376 1917744 R hypothetical protein complement(1917376..1917744) Lactococcus lactis subsp. lactis Il1403 1115514 NP_268007.1 CDS ytbE NC_002662.1 1917860 1918261 R similar to YazC of Bacillus subtilis; hypothetical protein complement(1917860..1918261) Lactococcus lactis subsp. lactis Il1403 1115515 NP_268008.1 CDS cysS NC_002662.1 1918254 1919600 R catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase complement(1918254..1919600) Lactococcus lactis subsp. lactis Il1403 1115516 NP_268009.1 CDS ytcA NC_002662.1 1919613 1920206 R hypothetical protein complement(1919613..1920206) Lactococcus lactis subsp. lactis Il1403 1115517 NP_268010.1 CDS cysE NC_002662.1 1920220 1920819 R serine family; serine acetyltransferase complement(1920220..1920819) Lactococcus lactis subsp. lactis Il1403 1115518 NP_268011.1 CDS ytcB NC_002662.1 1920926 1921696 R hypothetical protein complement(1920926..1921696) Lactococcus lactis subsp. lactis Il1403 1115519 NP_268012.1 CDS pnpA NC_002662.1 1921905 1924226 R degradation of RNA; polynucleotide phosphorylase/polyadenylase complement(1921905..1924226) Lactococcus lactis subsp. lactis Il1403 1115520 NP_268013.1 CDS ytcC NC_002662.1 1924510 1925655 R hypothetical protein complement(1924510..1925655) Lactococcus lactis subsp. lactis Il1403 1115521 NP_268014.1 CDS prsB NC_002662.1 1926020 1926985 D catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1926020..1926985 Lactococcus lactis subsp. lactis Il1403 1115522 NP_268015.1 CDS ytcD NC_002662.1 1927107 1927538 R hypothetical protein complement(1927107..1927538) Lactococcus lactis subsp. lactis Il1403 1115523 NP_268016.1 CDS nifS NC_002662.1 1927778 1928905 D energy metabolism, electron transport; similar to YrvO of Bacillus subtilis; cysteine sulfinate desulfinase/cysteine desulfurase, evidenced by COGnitor; pyridoxal-phosphate dependent aminotransferase 1927778..1928905 Lactococcus lactis subsp. lactis Il1403 1115524 NP_268017.1 CDS ytcE NC_002662.1 1928929 1929273 D hypothetical protein 1928929..1929273 Lactococcus lactis subsp. lactis Il1403 1115525 NP_268018.1 CDS tuf NC_002662.1 1929364 1930551 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(1929364..1930551) Lactococcus lactis subsp. lactis Il1403 1115526 NP_268019.1 CDS ytdA NC_002662.1 1930794 1930976 D hypothetical protein 1930794..1930976 Lactococcus lactis subsp. lactis Il1403 1115527 NP_268020.1 CDS ileS NC_002662.1 1931209 1934007 R IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase complement(1931209..1934007) Lactococcus lactis subsp. lactis Il1403 1115528 NP_268021.1 CDS ytdB NC_002662.1 1934323 1935249 R similar to cell division protein DivIVA of Bacillus subtilis; hypothetical protein complement(1934323..1935249) Lactococcus lactis subsp. lactis Il1403 1115529 NP_268022.1 CDS ytdC NC_002662.1 1935306 1936097 R similar to YlmH of Bacillus subtilis; hypothetical protein complement(1935306..1936097) Lactococcus lactis subsp. lactis Il1403 1115530 NP_268023.1 CDS ytdD NC_002662.1 1936094 1936369 R similar to YlmG of Bacillus subtilis; hypothetical protein complement(1936094..1936369) Lactococcus lactis subsp. lactis Il1403 1115531 NP_268024.1 CDS ytdE NC_002662.1 1936369 1936959 R similar to YlmF of Bacillus subtilis; hypothetical protein complement(1936369..1936959) Lactococcus lactis subsp. lactis Il1403 1115532 NP_268025.1 CDS ytdF NC_002662.1 1936993 1937670 R similar to YlmE of Bacillus subtilis; hypothetical protein complement(1936993..1937670) Lactococcus lactis subsp. lactis Il1403 1115533 NP_268026.1 CDS ftsZ NC_002662.1 1937674 1938927 R GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ complement(1937674..1938927) Lactococcus lactis subsp. lactis Il1403 1115534 NP_268027.1 CDS ftsA NC_002662.1 1938958 1940328 R cell division protein; hypothetical protein complement(1938958..1940328) Lactococcus lactis subsp. lactis Il1403 1115535 NP_268028.1 CDS yteA NC_002662.1 1940489 1941358 R similar to YitS protein from Bacillus subtilis.; hypothetical protein complement(1940489..1941358) Lactococcus lactis subsp. lactis Il1403 1115536 NP_268029.1 CDS trmH NC_002662.1 1941471 1942199 R tRNA modification; methylates guanosine-18 in various tRNAS; tRNA-guanosine methyltransferase complement(1941471..1942199) Lactococcus lactis subsp. lactis Il1403 1115537 NP_268030.2 CDS yteB NC_002662.1 1942345 1943463 R similar to oxidoreductases; hypothetical protein complement(1942345..1943463) Lactococcus lactis subsp. lactis Il1403 1115538 NP_268031.1 CDS yteC NC_002662.1 1943594 1944439 R aerobic energy metabolism; oxidoreductase complement(1943594..1944439) Lactococcus lactis subsp. lactis Il1403 1115539 NP_268032.1 CDS yteD NC_002662.1 1944451 1945779 R transport and binding protein; transmembrane efflux protein complement(1944451..1945779) Lactococcus lactis subsp. lactis Il1403 1115540 NP_268033.1 CDS rlrB NC_002662.1 1945945 1946823 R LysR-family regulator; LysR family transcriptional regulator complement(1945945..1946823) Lactococcus lactis subsp. lactis Il1403 1115541 NP_268034.1 CDS rmeA NC_002662.1 1946839 1947243 R MerR family of transcription regulators; transcriptional regulator complement(1946839..1947243) Lactococcus lactis subsp. lactis Il1403 1115542 NP_268035.1 CDS pepC NC_002662.1 1947325 1948635 R evidence experimental PMID:8439160; degradation of proteins, peptides, and glycopeptides; aminopeptidase C complement(1947325..1948635) Lactococcus lactis subsp. lactis Il1403 1115543 NP_268036.1 CDS yteE NC_002662.1 1948764 1949357 R hypothetical protein complement(1948764..1949357) Lactococcus lactis subsp. lactis Il1403 1115544 NP_268037.2 CDS pfs NC_002662.1 1949415 1950095 R enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase complement(1949415..1950095) Lactococcus lactis subsp. lactis Il1403 1115545 NP_268038.1 CDS ytfA NC_002662.1 1950128 1950406 R hypothetical protein complement(1950128..1950406) Lactococcus lactis subsp. lactis Il1403 1115546 NP_268039.1 CDS ytfB NC_002662.1 1950399 1950983 R hypothetical protein complement(1950399..1950983) Lactococcus lactis subsp. lactis Il1403 1115547 NP_268040.1 CDS glmU NC_002662.1 1951088 1952464 R forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase complement(1951088..1952464) Lactococcus lactis subsp. lactis Il1403 1115548 NP_268041.1 CDS proC NC_002662.1 1952692 1953480 D catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 1952692..1953480 Lactococcus lactis subsp. lactis Il1403 1115549 NP_268042.1 CDS tra983H NC_002662.1 1953555 1954502 R transposon related function; belongs to the IS30 family of transposase; transposase of IS983H complement(1953555..1954502) Lactococcus lactis subsp. lactis Il1403 1115550 NP_268043.1 CDS rpsO NC_002662.1 1954639 1954908 R primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 complement(1954639..1954908) Lactococcus lactis subsp. lactis Il1403 1115551 NP_268044.1 CDS pknB NC_002662.1 1955090 1956973 R translation; protein modification; serine/threonine protein kinase complement(1955090..1956973) Lactococcus lactis subsp. lactis Il1403 1115552 NP_268045.2 CDS pppL NC_002662.1 1956973 1957749 R translation; protein modification; serine/threonine phosphatase complement(1956973..1957749) Lactococcus lactis subsp. lactis Il1403 1115553 NP_268046.1 CDS sunL NC_002662.1 1957830 1959104 R RNA synthesis, modification, and DNA transcription; similar to RNA-binding Sun protein of Bacillus subtilis, predicted to be rRNA methylase; rRNA methylase complement(1957830..1959104) Lactococcus lactis subsp. lactis Il1403 1115554 NP_268047.1 CDS ytgH NC_002662.1 1959303 1959809 R similar to a 20 kD protein from sucrose-nisin transposon Tn5306; hypothetical protein complement(1959303..1959809) Lactococcus lactis subsp. lactis Il1403 1115555 YP_008998704.1 CDS L142734a NC_002662.1 1959830 1960018 R membrane protein; hypothetical protein complement(1959830..1960018) Lactococcus lactis subsp. lactis Il1403 18245220 NP_268048.1 CDS ytgA NC_002662.1 1960029 1960589 R hypothetical protein complement(1960029..1960589) Lactococcus lactis subsp. lactis Il1403 1115556 NP_268049.1 CDS ytgB NC_002662.1 1960617 1960859 R hypothetical protein complement(1960617..1960859) Lactococcus lactis subsp. lactis Il1403 1115557 NP_268050.1 CDS fmt NC_002662.1 1961034 1961993 R modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase complement(1961034..1961993) Lactococcus lactis subsp. lactis Il1403 1115558 NP_268051.2 CDS yteG NC_002662.1 1961990 1962454 R hypothetical protein complement(1961990..1962454) Lactococcus lactis subsp. lactis Il1403 1115559 NP_268052.1 CDS ytgC NC_002662.1 1962420 1962941 R similar to ADP-ribose pyrophosphatase or MutT protein of Bacillus subtilis; hypothetical protein complement(1962420..1962941) Lactococcus lactis subsp. lactis Il1403 1115560 NP_268053.1 CDS ytgD NC_002662.1 1962954 1963328 R hypothetical protein complement(1962954..1963328) Lactococcus lactis subsp. lactis Il1403 1115561 NP_268054.1 CDS priA NC_002662.1 1963387 1965726 R binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA complement(1963387..1965726) Lactococcus lactis subsp. lactis Il1403 1115562 NP_268055.1 CDS ytgE NC_002662.1 1965865 1966218 R Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega complement(1965865..1966218) Lactococcus lactis subsp. lactis Il1403 1115563 NP_268056.1 CDS gmk NC_002662.1 1966398 1967015 R Essential for recycling GMP and indirectly, cGMP; guanylate kinase complement(1966398..1967015) Lactococcus lactis subsp. lactis Il1403 1115564 NP_268057.1 CDS ytgF NC_002662.1 1967163 1968758 R protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP; phosphodiesterase complement(1967163..1968758) Lactococcus lactis subsp. lactis Il1403 1115565 NP_268058.1 CDS ytgG NC_002662.1 1968989 1969702 R 6-phosphogluconolactonase complement(1968989..1969702) Lactococcus lactis subsp. lactis Il1403 1115566 NP_835328.1 CDS L200068 NC_002662.1 1969807 1969941 R simialr to carboxy terminus of S-adenosylmethionine synthetase; hypothetical protein complement(1969807..1969941) Lactococcus lactis subsp. lactis Il1403 1115567 NP_268059.1 CDS metK NC_002662.1 1969978 1971177 R methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase complement(1969978..1971177) Lactococcus lactis subsp. lactis Il1403 1115568 NP_268060.1 CDS birA2 NC_002662.1 1972948 1973700 D COG says Biotin-(acetyl-CoA carboxylase) ligase; bifunctional biotin-[acetylCoA carboxylase] synthetase/ DNA-binding transcriptional repressor 1972948..1973700 Lactococcus lactis subsp. lactis Il1403 1115570 NP_268061.1 CDS ythA NC_002662.1 1973807 1974271 R similar to YvlC protein of Bacillus subtilis; probably stress-responsive transcription regulator, evidenced by COGnitor; hypothetical protein complement(1973807..1974271) Lactococcus lactis subsp. lactis Il1403 1115571 NP_268062.1 CDS ythB NC_002662.1 1974300 1974503 R similar to YvlC protein of Bacillus subtilis; probably stress-responsive transcription regulator, evidenced by COGnitor; hypothetical protein complement(1974300..1974503) Lactococcus lactis subsp. lactis Il1403 1115572 NP_268063.1 CDS ythC NC_002662.1 1974565 1975680 R similar to YvlB of Bacillus subtilis; hypothetical protein complement(1974565..1975680) Lactococcus lactis subsp. lactis Il1403 1115573 NP_268064.1 CDS acmB NC_002662.1 1975894 1977321 R cell envelope, murein sacculus and peptidoglycan; muramidase needed for cell separation and responsible for autolysis; N-acetylmuramoyl-L-alanine amidase complement(1975894..1977321) Lactococcus lactis subsp. lactis Il1403 1115574 NP_268065.1 CDS tra983I NC_002662.1 1977927 1978874 R transposon related function; belongs to the IS30 family of transposase; transposase of IS983I complement(1977927..1978874) Lactococcus lactis subsp. lactis Il1403 1115575 NP_268066.1 CDS fbaA NC_002662.1 1979402 1980298 R catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase complement(1979402..1980298) Lactococcus lactis subsp. lactis Il1403 1115576 NP_268067.1 CDS ytiA NC_002662.1 1986364 1987023 R hypothetical protein complement(1986364..1987023) Lactococcus lactis subsp. lactis Il1403 1115577 NP_268068.1 CDS thrS NC_002662.1 1987130 1989070 R catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase complement(1987130..1989070) Lactococcus lactis subsp. lactis Il1403 1115578 NP_268069.1 CDS ytjA NC_002662.1 1989614 1989931 R hypothetical protein complement(1989614..1989931) Lactococcus lactis subsp. lactis Il1403 1115579 NP_268070.1 CDS ytjD NC_002662.1 1991357 1991965 R hypothetical protein complement(1991357..1991965) Lactococcus lactis subsp. lactis Il1403 1115581 NP_268071.1 CDS upp NC_002662.1 1992107 1992742 R Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase complement(1992107..1992742) Lactococcus lactis subsp. lactis Il1403 1115582 NP_268072.1 CDS nah NC_002662.1 1992968 1994107 R transort and binding protein, cations; Na+/H+ antiporter complement(1992968..1994107) Lactococcus lactis subsp. lactis Il1403 1115583 NP_268073.1 CDS ytjE NC_002662.1 1994162 1995325 R energy metabolism, amino acids and amines; belongs to class-II of pyridoxal-phosphate-dependent aminotransferases; MALY/PATB subfamily; probably methionine specific aminotransferase; aminotransferase complement(1994162..1995325) Lactococcus lactis subsp. lactis Il1403 1115584 NP_268074.1 CDS metB1 NC_002662.1 1995572 1996660 R catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase complement(1995572..1996660) Lactococcus lactis subsp. lactis Il1403 1115585 NP_268075.1 CDS metA NC_002662.1 1996691 1997656 R catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase complement(1996691..1997656) Lactococcus lactis subsp. lactis Il1403 1115586 NP_268076.1 CDS ytjF NC_002662.1 1997806 1998366 R hypothetical protein complement(1997806..1998366) Lactococcus lactis subsp. lactis Il1403 1115587 NP_268078.1 CDS ytjH NC_002662.1 1999580 2000287 R hypothetical protein complement(1999580..2000287) Lactococcus lactis subsp. lactis Il1403 1115589 NP_268079.1 CDS yuaA NC_002662.1 2000601 2001545 R similar to CMP-binding-factor 1 of S.aureus; hypothetical protein complement(2000601..2001545) Lactococcus lactis subsp. lactis Il1403 1115590 NP_268080.1 CDS yuaB NC_002662.1 2001792 2003096 R hypothetical protein complement(2001792..2003096) Lactococcus lactis subsp. lactis Il1403 1115591 NP_268081.1 CDS rpe NC_002662.1 2003188 2003838 R pentose phosphate pathway; ribulose-phosphate 3-epimerase complement(2003188..2003838) Lactococcus lactis subsp. lactis Il1403 1115592 NP_268082.1 CDS yuaC NC_002662.1 2003897 2004154 R hypothetical protein complement(2003897..2004154) Lactococcus lactis subsp. lactis Il1403 1115593 NP_268083.1 CDS yuaD NC_002662.1 2004383 2005306 R EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase complement(2004383..2005306) Lactococcus lactis subsp. lactis Il1403 1115594 NP_268084.2 CDS yuaE NC_002662.1 2005366 2006430 R similar to extracellular protein Exp1 precursor; hypothetical protein complement(2005366..2006430) Lactococcus lactis subsp. lactis Il1403 1115595 NP_268085.1 CDS pheT NC_002662.1 2006657 2009050 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta complement(2006657..2009050) Lactococcus lactis subsp. lactis Il1403 1115596 NP_268086.1 CDS pheS NC_002662.1 2009087 2010127 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha complement(2009087..2010127) Lactococcus lactis subsp. lactis Il1403 1115597 NP_268087.1 CDS pdc NC_002662.1 2010581 2011114 D energy metabolism, amino acids and amines; specificity of the enzyme is not clearly defined; phenolic acid decarboxylase 2010581..2011114 Lactococcus lactis subsp. lactis Il1403 1115598 NP_268088.1 CDS tra983J NC_002662.1 2011426 2012373 D transposon related function; belongs to the IS30 family of transposase; transposase of IS983J 2011426..2012373 Lactococcus lactis subsp. lactis Il1403 1115599 NP_268089.1 CDS ps301 NC_002662.1 2013685 2014605 R prophage ps3 protein 01 complement(2013685..2014605) Lactococcus lactis subsp. lactis Il1403 1115600 NP_268090.1 CDS ps302 NC_002662.1 2014617 2014913 R prophage ps3 protein 02 complement(2014617..2014913) Lactococcus lactis subsp. lactis Il1403 1115601 NP_268091.1 CDS ps303 NC_002662.1 2015102 2015281 R prophage ps3 protein 03 complement(2015102..2015281) Lactococcus lactis subsp. lactis Il1403 1115602 NP_268092.1 CDS ps304 NC_002662.1 2015473 2015703 R prophage ps3 protein 04 complement(2015473..2015703) Lactococcus lactis subsp. lactis Il1403 1115603 NP_268093.1 CDS ps305 NC_002662.1 2015846 2016352 R prophage ps3 protein 05 complement(2015846..2016352) Lactococcus lactis subsp. lactis Il1403 1115604 NP_835329.1 CDS L200071 NC_002662.1 2016511 2016648 R similar to bacteriophage bIL311 Orf16; hypothetical protein complement(2016511..2016648) Lactococcus lactis subsp. lactis Il1403 1115605 NP_268094.1 CDS tra983K NC_002662.1 2016951 2017898 D transposon related function; belongs to the IS30 family of transposase; transposase of IS983K 2016951..2017898 Lactococcus lactis subsp. lactis Il1403 1115606 NP_268095.1 CDS ps306 NC_002662.1 2017986 2018348 R prophage ps3 protein 06 complement(2017986..2018348) Lactococcus lactis subsp. lactis Il1403 1115607 NP_268096.1 CDS ps307 NC_002662.1 2018365 2018937 R prophage ps3 protein 07 complement(2018365..2018937) Lactococcus lactis subsp. lactis Il1403 1115608 NP_268097.1 CDS ps308 NC_002662.1 2019099 2019305 R prophage ps3 protein 08 complement(2019099..2019305) Lactococcus lactis subsp. lactis Il1403 1115609 NP_268098.1 CDS ps309 NC_002662.1 2019324 2019506 R prophage ps3 protein 09 complement(2019324..2019506) Lactococcus lactis subsp. lactis Il1403 1115610 NP_268099.1 CDS ps310 NC_002662.1 2019875 2020189 R prophage ps3 protein 10 complement(2019875..2020189) Lactococcus lactis subsp. lactis Il1403 1115611 NP_268100.1 CDS ps311 NC_002662.1 2020102 2021571 R similar to a bacteriophage resistance protein from Lactococcus lactis; prophage ps3 protein 11 complement(2020102..2021571) Lactococcus lactis subsp. lactis Il1403 1115612 NP_268101.1 CDS ps312 NC_002662.1 2021582 2021851 R prophage ps3 protein 12 complement(2021582..2021851) Lactococcus lactis subsp. lactis Il1403 1115613 NP_835330.1 CDS L200072 NC_002662.1 2021848 2022000 R similar to bacteriophage bIL311 Orf7; hypothetical protein complement(2021848..2022000) Lactococcus lactis subsp. lactis Il1403 1115614 NP_835331.1 CDS L200073 NC_002662.1 2022088 2022252 R similar to bacteriophage bIL311 Orf6; hypothetical protein complement(2022088..2022252) Lactococcus lactis subsp. lactis Il1403 1115615 NP_835332.1 CDS L200074 NC_002662.1 2022254 2022424 R similar to bacteriophage bIL311 Orf5; hypothetical protein complement(2022254..2022424) Lactococcus lactis subsp. lactis Il1403 1115616 NP_835333.1 CDS L200075 NC_002662.1 2022504 2022629 R similar to bacteriophage bIL311 Orf4; hypothetical protein complement(2022504..2022629) Lactococcus lactis subsp. lactis Il1403 1115617 NP_268102.1 CDS ps313 NC_002662.1 2022663 2023178 R prophage ps3 protein 13 complement(2022663..2023178) Lactococcus lactis subsp. lactis Il1403 1115618 NP_268103.1 CDS ps314 NC_002662.1 2023293 2023499 R transcription regulator; similar to cro-like repressor of bacteriophage phig1e; prophage ps3 protein 14 complement(2023293..2023499) Lactococcus lactis subsp. lactis Il1403 1115619 NP_268104.1 CDS ps315 NC_002662.1 2023648 2024355 D prophage ps3 protein 15 2023648..2024355 Lactococcus lactis subsp. lactis Il1403 1115620 NP_268105.1 CDS ps316 NC_002662.1 2024436 2025635 D prophage ps3 protein 16; integrase 2024436..2025635 Lactococcus lactis subsp. lactis Il1403 1115621 NP_268106.1 CDS yucF NC_002662.1 2025839 2026378 D probably transcription regulator, evidenced by COGnitor; hypothetical protein 2025839..2026378 Lactococcus lactis subsp. lactis Il1403 1115622 NP_268107.1 CDS chiA NC_002662.1 2026545 2028023 D degradation of polysaccharides; hydrolysis of the beta-1,4 linkages of N-acetyl-D-glucosamine polymers of chitin; chitinase 2026545..2028023 Lactococcus lactis subsp. lactis Il1403 1115623 NP_268108.1 CDS yucG NC_002662.1 2028043 2028705 D central intermediary metabolism; degradation of polysaccharides; probably a secreted chitinase; chitin binding protein 2028043..2028705 Lactococcus lactis subsp. lactis Il1403 1115624 NP_268109.1 CDS purA NC_002662.1 2028748 2030040 R catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase complement(2028748..2030040) Lactococcus lactis subsp. lactis Il1403 1115625 NP_268110.1 CDS yudA NC_002662.1 2030313 2030933 R transport and binding protein; transporter complement(2030313..2030933) Lactococcus lactis subsp. lactis Il1403 1115626 NP_835334.1 CDS L200076 NC_002662.1 2031192 2031350 R similar to bacteriophage bIL310 Orf3; hypothetical protein complement(2031192..2031350) Lactococcus lactis subsp. lactis Il1403 1115627 NP_268111.1 CDS yudB NC_002662.1 2031520 2031987 R hypothetical protein complement(2031520..2031987) Lactococcus lactis subsp. lactis Il1403 1115628 NP_268112.1 CDS yudC NC_002662.1 2032053 2032730 R hypothetical protein complement(2032053..2032730) Lactococcus lactis subsp. lactis Il1403 1115629 NP_268113.1 CDS yudD NC_002662.1 2032821 2033324 R hypothetical protein complement(2032821..2033324) Lactococcus lactis subsp. lactis Il1403 1115630 NP_268114.1 CDS yudE NC_002662.1 2033404 2033655 R hypothetical protein complement(2033404..2033655) Lactococcus lactis subsp. lactis Il1403 1115631 NP_268115.1 CDS yudF NC_002662.1 2033751 2034074 R hypothetical protein complement(2033751..2034074) Lactococcus lactis subsp. lactis Il1403 1115632 NP_268116.2 CDS hslO NC_002662.1 2034313 2035179 D becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 2034313..2035179 Lactococcus lactis subsp. lactis Il1403 1115633 NP_268117.1 CDS yudH NC_002662.1 2035234 2035755 D dihydrofolate reductase, evidenced by COGnitor; hypothetical protein 2035234..2035755 Lactococcus lactis subsp. lactis Il1403 1115634 NP_268118.1 CDS yudI NC_002662.1 2035883 2036887 D aerobic energy metabolism; oxidoreductase 2035883..2036887 Lactococcus lactis subsp. lactis Il1403 1115635 NP_268119.1 CDS yudJ NC_002662.1 2037253 2038137 R similar to YpjC protein of Bacillus subtilis; hypothetical protein complement(2037253..2038137) Lactococcus lactis subsp. lactis Il1403 1115636 NP_268120.1 CDS yudK NC_002662.1 2038287 2039135 R similar to YpjC protein of Bacillus subtilis; hypothetical protein complement(2038287..2039135) Lactococcus lactis subsp. lactis Il1403 1115637 NP_268121.1 CDS yudL NC_002662.1 2039261 2040103 R similar to YitT protein of Bacillus subtilis; hypothetical protein complement(2039261..2040103) Lactococcus lactis subsp. lactis Il1403 1115638 NP_268122.1 CDS aspS NC_002662.1 2040170 2041942 R catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase complement(2040170..2041942) Lactococcus lactis subsp. lactis Il1403 1115639 NP_268124.1 CDS hisS NC_002662.1 2042397 2043689 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase complement(2042397..2043689) Lactococcus lactis subsp. lactis Il1403 1115641 NP_268125.1 CDS yueB NC_002662.1 2044002 2045162 R similar to positive regulator GadR of Lactococcus lactis; hypothetical protein complement(2044002..2045162) Lactococcus lactis subsp. lactis Il1403 1115642 NP_268126.1 CDS yueC NC_002662.1 2045406 2045981 R hypothetical protein complement(2045406..2045981) Lactococcus lactis subsp. lactis Il1403 1115643 NP_268127.1 CDS pgsA NC_002662.1 2046241 2046813 R membranes, lipoproteins, and porins; catalyzes the committed step to the synthesis of the acidic phospholipids; integral membrance protein; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase complement(2046241..2046813) Lactococcus lactis subsp. lactis Il1403 1115644 NP_268128.1 CDS yueD NC_002662.1 2046854 2047750 R hypothetical protein complement(2046854..2047750) Lactococcus lactis subsp. lactis Il1403 1115645 NP_268129.1 CDS yueE NC_002662.1 2047962 2049194 R degradation of proteins, peptides, and glycopeptides; similar to different proteases; protease complement(2047962..2049194) Lactococcus lactis subsp. lactis Il1403 1115646 NP_268130.1 CDS yueF NC_002662.1 2049235 2050491 R degradation of proteins, peptides, and glycopeptides; similar to several proteases; protease complement(2049235..2050491) Lactococcus lactis subsp. lactis Il1403 1115647 NP_268131.1 CDS yufA NC_002662.1 2050719 2051081 D hypothetical protein 2050719..2051081 Lactococcus lactis subsp. lactis Il1403 1115648 NP_268132.1 CDS recF NC_002662.1 2051081 2052157 D Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 2051081..2052157 Lactococcus lactis subsp. lactis Il1403 1115649 NP_268133.1 CDS pcaC NC_002662.1 2052244 2052612 R central intermediary metabolism; third step in the catabolism of protocatechuate to succinate and acetyl-CoA in the beta-ketoadipate pathway; gamma-carboxymuconolactone decarboxylase complement(2052244..2052612) Lactococcus lactis subsp. lactis Il1403 1115650 NP_268134.1 CDS rmeD NC_002662.1 2052690 2053067 D MerR family of transcription regulators; transcriptional regulator 2052690..2053067 Lactococcus lactis subsp. lactis Il1403 1115651 NP_268135.1 CDS yufC NC_002662.1 2053080 2054024 R hypothetical protein complement(2053080..2054024) Lactococcus lactis subsp. lactis Il1403 1115652 NP_268136.1 CDS galE NC_002662.1 2054147 2055127 R galactose metabolism; UDP-glucose 4-epimerase complement(2054147..2055127) Lactococcus lactis subsp. lactis Il1403 1115653 NP_268137.2 CDS lacZ NC_002662.1 2055179 2058175 R forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon; beta-D-galactosidase complement(2055179..2058175) Lactococcus lactis subsp. lactis Il1403 1115654 NP_268139.1 CDS galT NC_002662.1 2058844 2060325 R catalyzes the formation of alpha-D-glucose 1-phosphate and UDP-galactose from UDP-glucose and alpha-D-galactose 1-phosphate in galactose metabolism; galactose-1-phosphate uridylyltransferase complement(2058844..2060325) Lactococcus lactis subsp. lactis Il1403 1115657 NP_268140.1 CDS galK NC_002662.1 2060499 2061698 R catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase complement(2060499..2061698) Lactococcus lactis subsp. lactis Il1403 1115658 NP_268141.1 CDS galM NC_002662.1 2061725 2062744 R galactose metabolism; aldose 1-epimerase complement(2061725..2062744) Lactococcus lactis subsp. lactis Il1403 1115659 NP_268142.1 CDS yugA NC_002662.1 2064540 2065274 R RpiR family of transcription regulators; transcriptional regulator complement(2064540..2065274) Lactococcus lactis subsp. lactis Il1403 1115661 NP_268143.1 CDS yugB NC_002662.1 2065403 2066266 D aerobic energy metabolism; oxidoreductase 2065403..2066266 Lactococcus lactis subsp. lactis Il1403 1115662 NP_268144.1 CDS nadR NC_002662.1 2066475 2067614 R NadR family of transcription regulators; transcriptional regulator complement(2066475..2067614) Lactococcus lactis subsp. lactis Il1403 1115663 NP_268145.1 CDS yugC NC_002662.1 2067601 2068578 R aerobic energy metabolism; dehydrogenase complement(2067601..2068578) Lactococcus lactis subsp. lactis Il1403 1115664 NP_268146.1 CDS yugD NC_002662.1 2068776 2070068 R degradation of proteins, peptides, and glycopeptides; protease complement(2068776..2070068) Lactococcus lactis subsp. lactis Il1403 1115665 NP_268147.1 CDS yuhA NC_002662.1 2070324 2070491 R hypothetical protein complement(2070324..2070491) Lactococcus lactis subsp. lactis Il1403 1115666 NP_268148.1 CDS yuhB NC_002662.1 2070628 2071551 R degradation of proteins, peptides, and glycopeptides; protease complement(2070628..2071551) Lactococcus lactis subsp. lactis Il1403 1115667 NP_268149.1 CDS yuhC NC_002662.1 2071772 2072053 D hypothetical protein 2071772..2072053 Lactococcus lactis subsp. lactis Il1403 1115668 NP_268150.1 CDS yuhD NC_002662.1 2072076 2072897 R probably a SAM-dependent RNA methyltransferase, evidenced by COGnitor; hypothetical protein complement(2072076..2072897) Lactococcus lactis subsp. lactis Il1403 1115669 NP_268151.1 CDS yuhE NC_002662.1 2073015 2073641 D hypothetical protein 2073015..2073641 Lactococcus lactis subsp. lactis Il1403 1115670 NP_268152.1 CDS ecsB NC_002662.1 2073681 2074700 R transport and binding protein; similar to EcsB of Bacillus subtilis involved in the control of levels of exoamylase and other exoenzymes; ABC transporter permease complement(2073681..2074700) Lactococcus lactis subsp. lactis Il1403 1115671 NP_268153.1 CDS ecsA NC_002662.1 2074693 2075463 R transport and binding protein; similar to EcsA of Bacillus subtilis controlling levels of exoamylase and other exoenzymes; ABC transporter ATP-binding protein complement(2074693..2075463) Lactococcus lactis subsp. lactis Il1403 1115672 NP_268154.1 CDS yuhH NC_002662.1 2075482 2077335 R hypothetical protein complement(2075482..2077335) Lactococcus lactis subsp. lactis Il1403 1115673 NP_268155.1 CDS yuhI NC_002662.1 2077566 2077967 D hypothetical protein 2077566..2077967 Lactococcus lactis subsp. lactis Il1403 1115674 NP_268156.1 CDS yuhJ NC_002662.1 2077980 2078201 D hypothetical protein 2077980..2078201 Lactococcus lactis subsp. lactis Il1403 1115675 NP_268157.1 CDS rplA NC_002662.1 2078636 2079325 R in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 complement(2078636..2079325) Lactococcus lactis subsp. lactis Il1403 1115676 NP_268158.1 CDS rplK NC_002662.1 2079621 2080046 R binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 complement(2079621..2080046) Lactococcus lactis subsp. lactis Il1403 1115677 NP_268159.1 CDS yuiA NC_002662.1 2080271 2082148 D transport and binding protein, cations; similar to cadmium resistance protein of Lactococcus lactis; metal transporting ATPase 2080271..2082148 Lactococcus lactis subsp. lactis Il1403 1115678 NP_268160.1 CDS rcfA NC_002662.1 2082212 2082880 D CRP/FNR family of transcription regulators; transcriptional regulator 2082212..2082880 Lactococcus lactis subsp. lactis Il1403 1115679 NP_268161.1 CDS tra983L NC_002662.1 2083063 2084010 D transposon related function; belongs to the IS30 family of transposase; transposase of IS983L 2083063..2084010 Lactococcus lactis subsp. lactis Il1403 1115680 NP_268162.1 CDS yuiB NC_002662.1 2084031 2084240 R similar to YozE of Bacillus subtilis; hypothetical protein complement(2084031..2084240) Lactococcus lactis subsp. lactis Il1403 1115681 NP_268163.1 CDS pmsR NC_002662.1 2084276 2084794 R this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A complement(2084276..2084794) Lactococcus lactis subsp. lactis Il1403 1115682 NP_268164.1 CDS yuiC NC_002662.1 2084969 2085826 R similar to YitL protein of Bacillus subtilis; hypothetical protein complement(2084969..2085826) Lactococcus lactis subsp. lactis Il1403 1115683 NP_268165.1 CDS yuiD NC_002662.1 2085872 2086330 R hypothetical protein complement(2085872..2086330) Lactococcus lactis subsp. lactis Il1403 1115684 NP_268166.1 CDS frr NC_002662.1 2086423 2086980 R Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor complement(2086423..2086980) Lactococcus lactis subsp. lactis Il1403 1115685 NP_268167.1 CDS pyrH NC_002662.1 2087192 2087908 R Catalyzes the phosphorylation of UMP to UDP; uridylate kinase complement(2087192..2087908) Lactococcus lactis subsp. lactis Il1403 1115686 NP_268168.1 CDS yuiE NC_002662.1 2087993 2088445 R hypothetical protein complement(2087993..2088445) Lactococcus lactis subsp. lactis Il1403 1115687 NP_268169.1 CDS ackA2 NC_002662.1 2088579 2089766 R AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase complement(2088579..2089766) Lactococcus lactis subsp. lactis Il1403 1115688 NP_268170.1 CDS ackA1 NC_002662.1 2089923 2091110 R fermentation; first of two steps in the conversion of acetate to acetyl-CoA; acetate kinase complement(2089923..2091110) Lactococcus lactis subsp. lactis Il1403 1115689 NP_268171.1 CDS yujA NC_002662.1 2091305 2092243 R hypothetical protein complement(2091305..2092243) Lactococcus lactis subsp. lactis Il1403 1115690 NP_268172.1 CDS typA NC_002662.1 2092679 2094520 R GTP-binding protein; BipA; hypothetical protein complement(2092679..2094520) Lactococcus lactis subsp. lactis Il1403 1115691 NP_268173.1 CDS yujB NC_002662.1 2094699 2095157 R hypothetical protein complement(2094699..2095157) Lactococcus lactis subsp. lactis Il1403 1115692 NP_268174.1 CDS yujC NC_002662.1 2095173 2095946 R hypothetical protein complement(2095173..2095946) Lactococcus lactis subsp. lactis Il1403 1115693 NP_268175.1 CDS yujD NC_002662.1 2096283 2096909 R transport and binding protein; ABC transporter ATP-binding protein complement(2096283..2096909) Lactococcus lactis subsp. lactis Il1403 1115694 NP_268176.1 CDS yujE NC_002662.1 2096910 2098892 R hypothetical protein complement(2096910..2098892) Lactococcus lactis subsp. lactis Il1403 1115695 NP_268177.1 CDS yujF NC_002662.1 2098896 2099222 R hypothetical protein complement(2098896..2099222) Lactococcus lactis subsp. lactis Il1403 1115696 NP_268178.1 CDS yujG NC_002662.1 2099522 2100250 R hypothetical protein complement(2099522..2100250) Lactococcus lactis subsp. lactis Il1403 1115697 NP_268179.1 CDS yvaA NC_002662.1 2100443 2100664 D hypothetical protein 2100443..2100664 Lactococcus lactis subsp. lactis Il1403 1115698 NP_268180.1 CDS glk NC_002662.1 2100698 2101669 D energy metabolism, sugars; glucokinase 2100698..2101669 Lactococcus lactis subsp. lactis Il1403 1115699 NP_268181.1 CDS yvaB NC_002662.1 2101672 2102058 D hypothetical protein 2101672..2102058 Lactococcus lactis subsp. lactis Il1403 1115700 NP_268182.1 CDS dpsA NC_002662.1 2102141 2102587 R adaptations and atypical conditions; known in other bacteria also as starvation-inducible DNA-binding protein Dps; non-heme iron-binding ferritin complement(2102141..2102587) Lactococcus lactis subsp. lactis Il1403 1115701 NP_268183.1 CDS tra981J NC_002662.1 2102725 2103564 R evidence experimental PMID:8389385; transposon related function; related to a family of IS elements that includes IS2, IS3, IS150, IS600, IS629, IS861, IS904 and ISL1; transposase of IS981J complement(2102725..2103564) Lactococcus lactis subsp. lactis Il1403 1115702 NP_268184.1 CDS yuiI NC_002662.1 2103576 2103836 R transposon related function; orf1 of IS981; transposase complement(2103576..2103836) Lactococcus lactis subsp. lactis Il1403 1115703 NP_268185.1 CDS comC NC_002662.1 2103981 2104646 D transformation; required for processind and membrane assembling of ComG proteins.; type 4 prepilin-like protein specific leader peptidase 2103981..2104646 Lactococcus lactis subsp. lactis Il1403 1115704 NP_268186.1 CDS dinP NC_002662.1 2104597 2105688 R involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV complement(2104597..2105688) Lactococcus lactis subsp. lactis Il1403 1115705 NP_268187.1 CDS yvaD NC_002662.1 2105767 2106258 R hypothetical protein complement(2105767..2106258) Lactococcus lactis subsp. lactis Il1403 1115706 NP_268188.1 CDS arcD2 NC_002662.1 2106337 2107830 R transport and binding protein; amino acids, peptides and amines; arginine/ornitine antiporter complement(2106337..2107830) Lactococcus lactis subsp. lactis Il1403 1115707 NP_268189.1 CDS arcT NC_002662.1 2108022 2109152 R associated with arginine deiminase pathway genes; probably functions in arginine catabolism; transaminase complement(2108022..2109152) Lactococcus lactis subsp. lactis Il1403 1115708 NP_268190.1 CDS arcC2 NC_002662.1 2109416 2110360 R catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase complement(2109416..2110360) Lactococcus lactis subsp. lactis Il1403 1115709 NP_268191.1 CDS arcC1 NC_002662.1 2110392 2111336 R catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase complement(2110392..2111336) Lactococcus lactis subsp. lactis Il1403 1115710 NP_268192.1 CDS arcD1 NC_002662.1 2111456 2112928 R transport and binding protein; amino acids, peptides and amines; arginine/ornitine antiporter complement(2111456..2112928) Lactococcus lactis subsp. lactis Il1403 1115711 NP_268193.1 CDS arcB NC_002662.1 2113059 2114123 R catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase complement(2113059..2114123) Lactococcus lactis subsp. lactis Il1403 1115712 NP_268194.1 CDS arcA NC_002662.1 2114307 2115539 R catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase complement(2114307..2115539) Lactococcus lactis subsp. lactis Il1403 1115713 NP_268195.1 CDS argS NC_002662.1 2115841 2117535 R catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase complement(2115841..2117535) Lactococcus lactis subsp. lactis Il1403 1115714 NP_268196.1 CDS argR NC_002662.1 2117603 2118061 D regulator of arginine degradation pathway; arginine catabolic regulator 2117603..2118061 Lactococcus lactis subsp. lactis Il1403 1115715 NP_268197.2 CDS murC NC_002662.1 2118244 2119575 R Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase complement(2118244..2119575) Lactococcus lactis subsp. lactis Il1403 1115716 NP_268198.1 CDS yvcA NC_002662.1 2119778 2120371 R hypothetical protein complement(2119778..2120371) Lactococcus lactis subsp. lactis Il1403 1115717 NP_268199.1 CDS snf NC_002662.1 2120587 2123691 R DNA replication, restriction, modification, recombination, and repair; SWI/SNF family helicase complement(2120587..2123691) Lactococcus lactis subsp. lactis Il1403 1115718 NP_268200.1 CDS yvcC NC_002662.1 2123945 2128297 R hypothetical protein complement(2123945..2128297) Lactococcus lactis subsp. lactis Il1403 1115719 NP_268201.1 CDS poxL NC_002662.1 2128720 2130423 R aerobic energy metabolism; pyruvate oxidase complement(2128720..2130423) Lactococcus lactis subsp. lactis Il1403 1115720 NP_268202.1 CDS yvdA NC_002662.1 2130620 2131606 R hypothetical protein complement(2130620..2131606) Lactococcus lactis subsp. lactis Il1403 1115721 NP_268203.1 CDS yvdB NC_002662.1 2131679 2132458 R hypothetical protein complement(2131679..2132458) Lactococcus lactis subsp. lactis Il1403 1115722 NP_268204.1 CDS yvdC NC_002662.1 2132812 2133597 D hypothetical protein 2132812..2133597 Lactococcus lactis subsp. lactis Il1403 1115723 NP_268205.1 CDS yvdD NC_002662.1 2133640 2134509 R transport and binding protein, carbohydrates; organic alcohols and acids; similar to glycerol uptake facilitator GlpF of Bacillus subtilis; transmembrance channel MIP family; transporter complement(2133640..2134509) Lactococcus lactis subsp. lactis Il1403 1115724 NP_268206.1 CDS pepXP NC_002662.1 2134681 2136972 D catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue; x-prolyl-dipeptidyl aminopeptidase 2134681..2136972 Lactococcus lactis subsp. lactis Il1403 1115725 NP_268207.1 CDS yvdE NC_002662.1 2136974 2137684 D hypothetical protein 2136974..2137684 Lactococcus lactis subsp. lactis Il1403 1115726 NP_268208.1 CDS yvdF NC_002662.1 2137834 2138676 D transport and binding protein; amino acids, peptides and amines; amino acid ABC transporter substrate binding protein 2137834..2138676 Lactococcus lactis subsp. lactis Il1403 1115727 NP_268209.1 CDS yvdG NC_002662.1 2138764 2139897 R pyridine nucleotides; may be mercuric reductase; pyridine nucleotide-disulfide oxidoreductase complement(2138764..2139897) Lactococcus lactis subsp. lactis Il1403 1115728 NP_835336.1 CDS L200079 NC_002662.1 2139894 2140088 R hypothetical protein complement(2139894..2140088) Lactococcus lactis subsp. lactis Il1403 1115729 NP_268210.1 CDS gltX NC_002662.1 2140195 2141646 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(2140195..2141646) Lactococcus lactis subsp. lactis Il1403 1115730 NP_268211.1 CDS yveA NC_002662.1 2141810 2142340 R probably amidase, evidenced by COGnitor; hypothetical protein complement(2141810..2142340) Lactococcus lactis subsp. lactis Il1403 1115731 NP_268212.1 CDS yveB NC_002662.1 2142439 2143362 R hypothetical protein complement(2142439..2143362) Lactococcus lactis subsp. lactis Il1403 1115732 NP_268213.1 CDS yveC NC_002662.1 2143591 2144085 D hypothetical protein 2143591..2144085 Lactococcus lactis subsp. lactis Il1403 1115733 NP_268214.1 CDS yveD NC_002662.1 2144177 2144500 R hypothetical protein complement(2144177..2144500) Lactococcus lactis subsp. lactis Il1403 1115734 NP_268215.1 CDS yveE NC_002662.1 2144487 2144834 R hypothetical protein complement(2144487..2144834) Lactococcus lactis subsp. lactis Il1403 1115735 NP_268216.1 CDS yveF NC_002662.1 2144821 2145183 R hypothetical protein complement(2144821..2145183) Lactococcus lactis subsp. lactis Il1403 1115736 NP_268217.1 CDS yveG NC_002662.1 2145303 2145932 R hypothetical protein complement(2145303..2145932) Lactococcus lactis subsp. lactis Il1403 1115737 NP_268218.1 CDS yveH NC_002662.1 2145997 2147082 R hypothetical protein complement(2145997..2147082) Lactococcus lactis subsp. lactis Il1403 1115738 NP_268219.1 CDS tra983M NC_002662.1 2147273 2148220 R transposon related function; belongs to the IS30 family of transposase; transposase of IS983M complement(2147273..2148220) Lactococcus lactis subsp. lactis Il1403 1115739 NP_268220.1 CDS yveI NC_002662.1 2148393 2149079 D hypothetical protein 2148393..2149079 Lactococcus lactis subsp. lactis Il1403 1115740 NP_268221.1 CDS radA NC_002662.1 2149123 2150484 R Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA complement(2149123..2150484) Lactococcus lactis subsp. lactis Il1403 1115741 NP_268222.1 CDS yvfA NC_002662.1 2150646 2150873 R hypothetical protein complement(2150646..2150873) Lactococcus lactis subsp. lactis Il1403 1115742 NP_268223.1 CDS yvfB NC_002662.1 2151172 2151339 R hypothetical protein complement(2151172..2151339) Lactococcus lactis subsp. lactis Il1403 1115743 NP_268224.1 CDS rplQ NC_002662.1 2151688 2152068 R is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 complement(2151688..2152068) Lactococcus lactis subsp. lactis Il1403 1115744 NP_268225.1 CDS rpoA NC_002662.1 2152087 2153025 R catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha complement(2152087..2153025) Lactococcus lactis subsp. lactis Il1403 1115745 NP_268226.1 CDS rpsK NC_002662.1 2153073 2153456 R located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 complement(2153073..2153456) Lactococcus lactis subsp. lactis Il1403 1115746 NP_268227.1 CDS rpsM NC_002662.1 2153477 2153842 R located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 complement(2153477..2153842) Lactococcus lactis subsp. lactis Il1403 1115747 NP_268228.1 CDS rpmJ NC_002662.1 2153860 2153976 R smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 complement(2153860..2153976) Lactococcus lactis subsp. lactis Il1403 1115748 NP_268229.1 CDS infA NC_002662.1 2154030 2154248 R stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 complement(2154030..2154248) Lactococcus lactis subsp. lactis Il1403 1115749 NP_268230.1 CDS tra904H NC_002662.1 2154611 2155372 R evidence experimental PMID:1328163; transposon related function; IS3/IS150/IS904 family transposase; transposase of IS904H complement(2154611..2155372) Lactococcus lactis subsp. lactis Il1403 1115750 NP_268231.1 CDS yvfD NC_002662.1 2155468 2155758 R trasposon related functions; hypothetical protein complement(2155468..2155758) Lactococcus lactis subsp. lactis Il1403 1115751 NP_268232.1 CDS tra1077F NC_002662.1 2155831 2156649 R evidence experimental PMID:1328163; transposon related function; IS3/IS150/IS904 family transposase; IS1077F transposase complement(2155831..2156649) Lactococcus lactis subsp. lactis Il1403 1115752 NP_268233.1 CDS yvfC NC_002662.1 2156646 2157203 R transposon related function; hypothetical protein complement(2156646..2157203) Lactococcus lactis subsp. lactis Il1403 1115753 NP_268234.1 CDS adk NC_002662.1 2157280 2157927 R essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase complement(2157280..2157927) Lactococcus lactis subsp. lactis Il1403 1115754 NP_268235.1 CDS secY NC_002662.1 2158067 2159386 R forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY complement(2158067..2159386) Lactococcus lactis subsp. lactis Il1403 1115755 NP_268236.1 CDS rplO NC_002662.1 2159464 2159907 R late assembly protein; 50S ribosomal protein L15 complement(2159464..2159907) Lactococcus lactis subsp. lactis Il1403 1115756 NP_268237.1 CDS rpmD NC_002662.1 2160182 2160361 R L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 complement(2160182..2160361) Lactococcus lactis subsp. lactis Il1403 1115757 NP_268238.1 CDS rpsE NC_002662.1 2160372 2160878 R located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 complement(2160372..2160878) Lactococcus lactis subsp. lactis Il1403 1115758 NP_268239.1 CDS rplR NC_002662.1 2160897 2161244 R binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 complement(2160897..2161244) Lactococcus lactis subsp. lactis Il1403 1115759 NP_268240.1 CDS rplF NC_002662.1 2161460 2161996 R ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 complement(2161460..2161996) Lactococcus lactis subsp. lactis Il1403 1115760 NP_268241.1 CDS rpsH NC_002662.1 2162213 2162611 R binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 complement(2162213..2162611) Lactococcus lactis subsp. lactis Il1403 1115761 NP_268242.1 CDS yvgA NC_002662.1 2162827 2163411 R hypothetical protein complement(2162827..2163411) Lactococcus lactis subsp. lactis Il1403 1115762 NP_268243.1 CDS rpsN NC_002662.1 2163562 2163747 R located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 complement(2163562..2163747) Lactococcus lactis subsp. lactis Il1403 1115763 NP_268244.1 CDS rplE NC_002662.1 2163766 2164308 R part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 complement(2163766..2164308) Lactococcus lactis subsp. lactis Il1403 1115764 NP_268245.1 CDS rplX NC_002662.1 2164328 2164633 R assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 complement(2164328..2164633) Lactococcus lactis subsp. lactis Il1403 1115765 NP_268246.1 CDS rplN NC_002662.1 2164767 2165135 R binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 complement(2164767..2165135) Lactococcus lactis subsp. lactis Il1403 1115766 NP_268247.1 CDS rpsQ NC_002662.1 2165158 2165418 R primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 complement(2165158..2165418) Lactococcus lactis subsp. lactis Il1403 1115767 NP_268248.1 CDS rpmC NC_002662.1 2165439 2165648 R one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 complement(2165439..2165648) Lactococcus lactis subsp. lactis Il1403 1115768 NP_268249.1 CDS rplP NC_002662.1 2165648 2166061 R located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 complement(2165648..2166061) Lactococcus lactis subsp. lactis Il1403 1115769 NP_268250.1 CDS rpsC NC_002662.1 2166065 2166718 R forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 complement(2166065..2166718) Lactococcus lactis subsp. lactis Il1403 1115770 NP_268251.1 CDS rplV NC_002662.1 2166731 2167078 R binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 complement(2166731..2167078) Lactococcus lactis subsp. lactis Il1403 1115771 NP_268252.1 CDS rpsS NC_002662.1 2167094 2167372 R protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 complement(2167094..2167372) Lactococcus lactis subsp. lactis Il1403 1115772 NP_268253.1 CDS rplB NC_002662.1 2167532 2168362 R one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 complement(2167532..2168362) Lactococcus lactis subsp. lactis Il1403 1115773 NP_268254.1 CDS rplW NC_002662.1 2168378 2168671 R binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 complement(2168378..2168671) Lactococcus lactis subsp. lactis Il1403 1115774 NP_268255.1 CDS rplD NC_002662.1 2168671 2169297 R L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 complement(2168671..2169297) Lactococcus lactis subsp. lactis Il1403 1115775 NP_268256.1 CDS rplC NC_002662.1 2169323 2169946 R binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 complement(2169323..2169946) Lactococcus lactis subsp. lactis Il1403 1115776 NP_268257.1 CDS rpsJ NC_002662.1 2169965 2170273 R NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 complement(2169965..2170273) Lactococcus lactis subsp. lactis Il1403 1115777 NP_268258.1 CDS mscL NC_002662.1 2170586 2170954 D forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 2170586..2170954 Lactococcus lactis subsp. lactis Il1403 1115778 NP_268259.1 CDS yvhA NC_002662.1 2170994 2172196 R similar to MATE efflux family transporter proteins; hypothetical protein complement(2170994..2172196) Lactococcus lactis subsp. lactis Il1403 1115779 NP_268260.1 CDS thrC NC_002662.1 2172280 2173770 R catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase complement(2172280..2173770) Lactococcus lactis subsp. lactis Il1403 1115780 NP_268261.1 CDS nusG NC_002662.1 2173872 2174429 R Modulates Rho-dependent transcription termination; transcription antitermination protein NusG complement(2173872..2174429) Lactococcus lactis subsp. lactis Il1403 1115781 NP_268262.1 CDS secE NC_002662.1 2174627 2174821 R forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE complement(2174627..2174821) Lactococcus lactis subsp. lactis Il1403 1115782 NP_268263.1 CDS rpmG NC_002662.1 2174932 2175081 R in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif; 50S ribosomal protein L33 complement(2174932..2175081) Lactococcus lactis subsp. lactis Il1403 1115783 NP_268264.1 CDS yvhB NC_002662.1 2175122 2176939 R hypothetical protein complement(2175122..2176939) Lactococcus lactis subsp. lactis Il1403 1115784 NP_268265.1 CDS pbp2A NC_002662.1 2177041 2179272 R murein sacculus and peptidoglycan; penicillin-binding protein 2a complement(2177041..2179272) Lactococcus lactis subsp. lactis Il1403 1115785 NP_268266.1 CDS yviA NC_002662.1 2179581 2180216 R hypothetical protein complement(2179581..2180216) Lactococcus lactis subsp. lactis Il1403 1115786 NP_268267.1 CDS yviB NC_002662.1 2180233 2180664 R hypothetical protein complement(2180233..2180664) Lactococcus lactis subsp. lactis Il1403 1115787 NP_268268.1 CDS yviC NC_002662.1 2180778 2181155 R energy metabolism, electron transport; FMN-binding protein complement(2180778..2181155) Lactococcus lactis subsp. lactis Il1403 1115788 NP_268269.1 CDS rluA NC_002662.1 2181360 2182226 D pseudouridine synthase 2181360..2182226 Lactococcus lactis subsp. lactis Il1403 1115789 NP_268270.1 CDS zitP NC_002662.1 2182265 2183074 R transort and binding protein, cations; zinc ABC transporter permease complement(2182265..2183074) Lactococcus lactis subsp. lactis Il1403 1115790 NP_268271.1 CDS zitQ NC_002662.1 2183067 2183804 R transort and binding protein, cations; zinc ABC transporter ATP binding protein complement(2183067..2183804) Lactococcus lactis subsp. lactis Il1403 1115791 NP_268272.1 CDS zitS NC_002662.1 2183981 2184823 R transort and binding protein, cations; zinc ABC transporter substrate binding protein complement(2183981..2184823) Lactococcus lactis subsp. lactis Il1403 1115792 NP_268273.1 CDS zitR NC_002662.1 2184820 2185257 R MarR-family regulators; similar to AdcR repressor of adc locus, affecting competence in Streptococcus pneumoniae; zinc transport transcription regulator complement(2184820..2185257) Lactococcus lactis subsp. lactis Il1403 1115793 NP_268274.1 CDS yviH NC_002662.1 2185338 2185622 R hypothetical protein complement(2185338..2185622) Lactococcus lactis subsp. lactis Il1403 1115794 NP_268275.1 CDS yviI NC_002662.1 2185661 2186047 R hypothetical protein complement(2185661..2186047) Lactococcus lactis subsp. lactis Il1403 1115795 NP_268276.1 CDS yviJ NC_002662.1 2186070 2186366 R hypothetical protein complement(2186070..2186366) Lactococcus lactis subsp. lactis Il1403 1115796 NP_268277.1 CDS comGD NC_002662.1 2186338 2186769 R competence protein; transformation; required for the assembly of the competence membrane machinery; protein ComGD complement(2186338..2186769) Lactococcus lactis subsp. lactis Il1403 1115797 NP_268278.1 CDS comGC NC_002662.1 2186729 2187112 R competence protein; transformation; required for the assembly of the competence membrane machinery; protein ComGC complement(2186729..2187112) Lactococcus lactis subsp. lactis Il1403 1115798 NP_268279.1 CDS comGB NC_002662.1 2187126 2188199 R competence protein; transformation; required for the assembly of the competence membrane machinery; PULE/OUTE/EXEE/XPSE/XCPR family; protein ComGB complement(2187126..2188199) Lactococcus lactis subsp. lactis Il1403 1115799 NP_268280.1 CDS comGA NC_002662.1 2188093 2189031 R competence protein; transformation required for the assembly of the competence membrane machinery; PULE/OUTE/EXEE/XPSE/XCPR family; protein ComGA complement(2188093..2189031) Lactococcus lactis subsp. lactis Il1403 1115800 NP_268281.1 CDS polC NC_002662.1 2189151 2194127 R catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity; DNA polymerase III PolC complement(2189151..2194127) Lactococcus lactis subsp. lactis Il1403 1115801 NP_268282.1 CDS yvjA NC_002662.1 2194240 2194776 R hypothetical protein complement(2194240..2194776) Lactococcus lactis subsp. lactis Il1403 1115802 NP_268283.1 CDS noxD NC_002662.1 2194782 2196113 R aerobic energy metabolism; NADH oxidase complement(2194782..2196113) Lactococcus lactis subsp. lactis Il1403 1115803 NP_268284.1 CDS proS NC_002662.1 2196129 2197979 R catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase complement(2196129..2197979) Lactococcus lactis subsp. lactis Il1403 1115804 NP_268285.1 CDS yvjB NC_002662.1 2198049 2199335 R hypothetical protein complement(2198049..2199335) Lactococcus lactis subsp. lactis Il1403 1115805 NP_268286.1 CDS cdsA NC_002662.1 2199354 2200157 R membranes, lipoproteins, and porins; integral membrance protein; phosphatidate cytidylyltransferase complement(2199354..2200157) Lactococcus lactis subsp. lactis Il1403 1115806 NP_268287.1 CDS uppS NC_002662.1 2200157 2200891 R catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; UDP pyrophosphate synthase complement(2200157..2200891) Lactococcus lactis subsp. lactis Il1403 1115807 NP_268288.1 CDS ywaB NC_002662.1 2201263 2201595 R hypothetical protein complement(2201263..2201595) Lactococcus lactis subsp. lactis Il1403 1115808 NP_268291.2 CDS ywaE NC_002662.1 2202406 2202885 R SPOUT methyltransferase; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(2202406..2202885) Lactococcus lactis subsp. lactis Il1403 1115811 NP_268292.1 CDS tra983N NC_002662.1 2202924 2203871 R transposon related function; belongs to the IS30 family of transposase; transposase of IS983N complement(2202924..2203871) Lactococcus lactis subsp. lactis Il1403 1115812 NP_268293.1 CDS htrA NC_002662.1 2204341 2205567 D evidence experimental PMID:10712686; degradation of proteins, peptides, and glycopeptides. this protease is responsible for degradation of secreted hybrid proteins; exported serine protease 2204341..2205567 Lactococcus lactis subsp. lactis Il1403 1115813 NP_268294.1 CDS ywaF NC_002662.1 2205693 2206691 D surface polysaccharides, lipopolysaccharides and antigens; similar to CpoA of Streptococcus pneumoniae, supposed to be involved in lipopolysaccharide core biosynthesis; glycosyltransferase 2205693..2206691 Lactococcus lactis subsp. lactis Il1403 1115814 NP_268295.1 CDS ywaG NC_002662.1 2206817 2208157 D surface polysaccharides, lipopolysaccharides and antigens; lipopolysaccharide biosynthesis protein 2206817..2208157 Lactococcus lactis subsp. lactis Il1403 1115815 NP_268296.1 CDS ywaH NC_002662.1 2208265 2208489 D hypothetical protein 2208265..2208489 Lactococcus lactis subsp. lactis Il1403 1115816 NP_268297.1 CDS ywaI NC_002662.1 2208631 2209635 D hypothetical protein 2208631..2209635 Lactococcus lactis subsp. lactis Il1403 1115817 NP_268298.1 CDS ywbA NC_002662.1 2209676 2210428 R hypothetical protein complement(2209676..2210428) Lactococcus lactis subsp. lactis Il1403 1115818 NP_268299.1 CDS polA NC_002662.1 2210775 2213408 R has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I complement(2210775..2213408) Lactococcus lactis subsp. lactis Il1403 1115819 NP_268300.1 CDS ywbB NC_002662.1 2213646 2214455 D hypothetical protein 2213646..2214455 Lactococcus lactis subsp. lactis Il1403 1115820 NP_268301.1 CDS rliDA NC_002662.1 2214455 2214865 D LacI-family regulators; probably the N-terminal part of rliD, interrupted by transposon insertion; transcriptional regulator 2214455..2214865 Lactococcus lactis subsp. lactis Il1403 1115821 NP_268302.1 CDS tra904I NC_002662.1 2214945 2215706 R evidence experimental PMID:1328163; transposon related function; IS3/IS150/IS904 family transposase; transposase of IS904I complement(2214945..2215706) Lactococcus lactis subsp. lactis Il1403 1115822 NP_268303.1 CDS yvjF NC_002662.1 2215802 2216092 R transposon related function; hypothetical protein complement(2215802..2216092) Lactococcus lactis subsp. lactis Il1403 1115823 NP_268304.1 CDS tra1077G NC_002662.1 2216165 2216983 R evidence experimental PMID:1328163; transposon related function. IS3/IS150/IS904 family transposase; IS1077G transposase complement(2216165..2216983) Lactococcus lactis subsp. lactis Il1403 1115824 NP_268305.1 CDS ywbC NC_002662.1 2216980 2217537 R transposon related function; hypothetical protein complement(2216980..2217537) Lactococcus lactis subsp. lactis Il1403 1115825 NP_268306.1 CDS rliDB NC_002662.1 2217579 2218112 D LacI-family regulators; probably the C-terminal part of rliD, interrupted by transposon insertion; transcriptional regulator 2217579..2218112 Lactococcus lactis subsp. lactis Il1403 1115826 NP_268307.1 CDS comX NC_002662.1 2223528 2223956 R competence regulator; transformation; similar to ComX1 from Streptococcus pneumoniae. Probably a sigma factor, involved in regulation of competence; protein ComX complement(2223528..2223956) Lactococcus lactis subsp. lactis Il1403 1115827 NP_268308.1 CDS ezrA NC_002662.1 2224277 2226007 R acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation; septation ring formation regulator EzrA complement(2224277..2226007) Lactococcus lactis subsp. lactis Il1403 1115828 NP_268309.1 CDS tsf NC_002662.1 2226193 2227221 R EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts complement(2226193..2227221) Lactococcus lactis subsp. lactis Il1403 1115829 NP_268310.1 CDS rpsB NC_002662.1 2227343 2228110 R one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 complement(2227343..2228110) Lactococcus lactis subsp. lactis Il1403 1115830 NP_268311.1 CDS ywcC NC_002662.1 2228469 2229494 D similar to YkbG of Bacillus subtilis; hypothetical protein 2228469..2229494 Lactococcus lactis subsp. lactis Il1403 1115831 NP_268312.1 CDS adhE NC_002662.1 2229727 2232438 D evidence experimental PMID:9620952; energy metabolism; fermentation; bifunctional acetaldehyde-CoA/alcohol dehydrogenase 2229727..2232438 Lactococcus lactis subsp. lactis Il1403 1115832 NP_268313.1 CDS ywdA NC_002662.1 2232776 2233273 R hypothetical protein complement(2232776..2233273) Lactococcus lactis subsp. lactis Il1403 1115833 NP_268314.1 CDS ywdB NC_002662.1 2233260 2233469 R hypothetical protein complement(2233260..2233469) Lactococcus lactis subsp. lactis Il1403 1115834 NP_268315.1 CDS ywdC NC_002662.1 2233466 2234293 R hypothetical protein complement(2233466..2234293) Lactococcus lactis subsp. lactis Il1403 1115835 NP_268316.1 CDS ywdD NC_002662.1 2234286 2236409 R hypothetical protein complement(2234286..2236409) Lactococcus lactis subsp. lactis Il1403 1115836 NP_268317.1 CDS ywdE NC_002662.1 2236512 2237369 R general regulatory function; transcriptional regulator complement(2236512..2237369) Lactococcus lactis subsp. lactis Il1403 1115837 NP_268318.1 CDS ywdF NC_002662.1 2237490 2238518 R hypothetical protein complement(2237490..2238518) Lactococcus lactis subsp. lactis Il1403 1115838 NP_268319.1 CDS coaD NC_002662.1 2238505 2239002 R Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase complement(2238505..2239002) Lactococcus lactis subsp. lactis Il1403 1115839 NP_268320.1 CDS ywdG NC_002662.1 2239050 2239616 R N6-adenine-specific methylase, evidenced by COGnitor; similar to type II DNA modification methyltransferase; hypothetical protein complement(2239050..2239616) Lactococcus lactis subsp. lactis Il1403 1115840 NP_268321.1 CDS yweA NC_002662.1 2239760 2240980 R transport and binding protein; multidrug resistance; similar to the integral membrane protein LmrP from Lactococcus lactis; membrane protein complement(2239760..2240980) Lactococcus lactis subsp. lactis Il1403 1115841 NP_268322.1 CDS lmrP NC_002662.1 2241064 2242290 R integral membrane protein; transport and binding protein; multidrug resistance; there is no connection with the lmrA gene; LmrP complement(2241064..2242290) Lactococcus lactis subsp. lactis Il1403 1115842 NP_268323.1 CDS sigX NC_002662.1 2242478 2242972 D RNA synthesis, modification, and DNA transcription; RNA polymerase ECF sigma factor 2242478..2242972 Lactococcus lactis subsp. lactis Il1403 1115843 NP_268324.1 CDS yweB NC_002662.1 2242996 2244102 D hypothetical protein 2242996..2244102 Lactococcus lactis subsp. lactis Il1403 1115844 NP_268325.1 CDS pgi NC_002662.1 2244198 2245544 R functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase complement(2244198..2245544) Lactococcus lactis subsp. lactis Il1403 1115845 NP_268326.1 CDS yweC NC_002662.1 2245888 2246394 D hypothetical protein 2245888..2246394 Lactococcus lactis subsp. lactis Il1403 1115846 NP_268327.1 CDS yweD NC_002662.1 2246428 2247273 R hypothetical protein complement(2246428..2247273) Lactococcus lactis subsp. lactis Il1403 1115847 NP_268328.1 CDS yweE NC_002662.1 2247500 2247778 D hypothetical protein 2247500..2247778 Lactococcus lactis subsp. lactis Il1403 1115848 NP_268329.1 CDS yweF NC_002662.1 2247891 2248223 D hypothetical protein 2247891..2248223 Lactococcus lactis subsp. lactis Il1403 1115849 NP_268330.1 CDS valS NC_002662.1 2248267 2250909 R valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase complement(2248267..2250909) Lactococcus lactis subsp. lactis Il1403 1115850 NP_268331.1 CDS ywfA NC_002662.1 2251165 2251821 R hypothetical protein complement(2251165..2251821) Lactococcus lactis subsp. lactis Il1403 1115851 NP_268332.1 CDS ywfB NC_002662.1 2252098 2252346 R hypothetical protein complement(2252098..2252346) Lactococcus lactis subsp. lactis Il1403 1115852 NP_268333.1 CDS ywfC NC_002662.1 2252385 2252729 R hypothetical protein complement(2252385..2252729) Lactococcus lactis subsp. lactis Il1403 1115853 NP_268334.1 CDS ywfD NC_002662.1 2252730 2253239 R hypothetical protein complement(2252730..2253239) Lactococcus lactis subsp. lactis Il1403 1115854 NP_268335.1 CDS ywfE NC_002662.1 2253394 2254101 R hypothetical protein complement(2253394..2254101) Lactococcus lactis subsp. lactis Il1403 1115855 NP_268336.1 CDS ywfF NC_002662.1 2254433 2255974 R hypothetical protein complement(2254433..2255974) Lactococcus lactis subsp. lactis Il1403 1115856 NP_268337.1 CDS ywfG NC_002662.1 2256203 2258983 R hypothetical protein complement(2256203..2258983) Lactococcus lactis subsp. lactis Il1403 1115857 NP_268338.1 CDS ywfH NC_002662.1 2259052 2259525 R hypothetical protein complement(2259052..2259525) Lactococcus lactis subsp. lactis Il1403 1115858 NP_268339.1 CDS recX NC_002662.1 2259811 2260623 D binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 2259811..2260623 Lactococcus lactis subsp. lactis Il1403 1115859 NP_268340.1 CDS tra983O NC_002662.1 2267576 2268523 R transposon related function; belongs to the IS30 family of transposase; transposase of IS983O complement(2267576..2268523) Lactococcus lactis subsp. lactis Il1403 1115861 NP_268341.1 CDS gntK NC_002662.1 2268572 2270131 R energy metabolism, sugars; gluconate kinase complement(2268572..2270131) Lactococcus lactis subsp. lactis Il1403 1115862 NP_268342.1 CDS gntZ NC_002662.1 2270252 2271160 R similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate; 6-phosphogluconate dehydrogenase complement(2270252..2271160) Lactococcus lactis subsp. lactis Il1403 1115863 NP_268343.1 CDS gntR NC_002662.1 2271521 2272369 D RpiR family of transcription regulators; probably involved in gnt operon regulation; transcriptional regulator 2271521..2272369 Lactococcus lactis subsp. lactis Il1403 1115864 NP_268344.1 CDS ywhA NC_002662.1 2272407 2272715 D hypothetical protein 2272407..2272715 Lactococcus lactis subsp. lactis Il1403 1115865 NP_268345.1 CDS ywhB NC_002662.1 2272789 2273562 R probably a phosphohydrolase, evidenced by COGnitor; hypothetical protein complement(2272789..2273562) Lactococcus lactis subsp. lactis Il1403 1115866 NP_268346.1 CDS rpsR NC_002662.1 2273762 2274007 R binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 complement(2273762..2274007) Lactococcus lactis subsp. lactis Il1403 1115867 NP_268347.1 CDS ssbB NC_002662.1 2274181 2274681 R binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein complement(2274181..2274681) Lactococcus lactis subsp. lactis Il1403 1115868 NP_268348.1 CDS rpsF NC_002662.1 2274711 2275004 R binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 complement(2274711..2275004) Lactococcus lactis subsp. lactis Il1403 1115869 NP_268349.1 CDS uppP NC_002662.1 2275196 2276050 R BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; UDP pyrophosphate phosphatase complement(2275196..2276050) Lactococcus lactis subsp. lactis Il1403 1115870 NP_268350.1 CDS lysP NC_002662.1 2276518 2278038 D transport and binding protein; amino acids, peptides and amines; there is another lysine specific permease LysQ; lysine specific permease 2276518..2278038 Lactococcus lactis subsp. lactis Il1403 1115871 NP_268351.1 CDS dnaH NC_002662.1 2278073 2279731 R catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau complement(2278073..2279731) Lactococcus lactis subsp. lactis Il1403 1115872 NP_268352.1 CDS ywiA NC_002662.1 2279780 2280421 R hypothetical protein complement(2279780..2280421) Lactococcus lactis subsp. lactis Il1403 1115873 NP_268353.1 CDS ywiB NC_002662.1 2280453 2280941 R hypothetical protein complement(2280453..2280941) Lactococcus lactis subsp. lactis Il1403 1115874 NP_268354.1 CDS ywiC NC_002662.1 2281025 2281297 D similar to N-terminal part of chorismate mutases from several species; hypothetical protein 2281025..2281297 Lactococcus lactis subsp. lactis Il1403 1115875 NP_268355.1 CDS ywiD NC_002662.1 2281386 2281832 R hypothetical protein complement(2281386..2281832) Lactococcus lactis subsp. lactis Il1403 1115876 NP_268356.1 CDS ywiE NC_002662.1 2282050 2282250 D hypothetical protein 2282050..2282250 Lactococcus lactis subsp. lactis Il1403 1115877 NP_268357.1 CDS glnA NC_002662.1 2282309 2283649 R glutamate family; glutamine synthetase complement(2282309..2283649) Lactococcus lactis subsp. lactis Il1403 1115878 NP_268358.2 CDS glnR NC_002662.1 2283711 2284076 R MerR family of transcription regulators; glutamine synthetase complement(2283711..2284076) Lactococcus lactis subsp. lactis Il1403 1115879 NP_268359.1 CDS ptpL NC_002662.1 2284177 2284614 R protein modification; tyrosine phosphatase complement(2284177..2284614) Lactococcus lactis subsp. lactis Il1403 1115880 NP_268360.1 CDS ywiG NC_002662.1 2285027 2285644 R transport and binding protein; ABC transporter ATP-binding protein complement(2285027..2285644) Lactococcus lactis subsp. lactis Il1403 1115881 NP_268361.1 CDS ywiH NC_002662.1 2285641 2286825 R transport and binding protein; ABC transporter permease complement(2285641..2286825) Lactococcus lactis subsp. lactis Il1403 1115882 NP_268362.1 CDS ywiI NC_002662.1 2287402 2288286 R similar to a positive regulator GadR from Lactococcus lactis; transcriptional regulator complement(2287402..2288286) Lactococcus lactis subsp. lactis Il1403 1115883 NP_268363.1 CDS ruvB NC_002662.1 2288423 2289397 R promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB complement(2288423..2289397) Lactococcus lactis subsp. lactis Il1403 1115884 NP_268364.1 CDS ruvA NC_002662.1 2289550 2290143 R plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA complement(2289550..2290143) Lactococcus lactis subsp. lactis Il1403 1115885 NP_268365.1 CDS mutL NC_002662.1 2290256 2292343 R This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein complement(2290256..2292343) Lactococcus lactis subsp. lactis Il1403 1115886 NP_268366.1 CDS ywjA NC_002662.1 2292355 2293050 R hypothetical protein complement(2292355..2293050) Lactococcus lactis subsp. lactis Il1403 1115887 NP_268367.1 CDS hexA NC_002662.1 2293165 2295687 R This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS complement(2293165..2295687) Lactococcus lactis subsp. lactis Il1403 1115888 NP_268368.1 CDS ywjB NC_002662.1 2295881 2296228 R hypothetical protein complement(2295881..2296228) Lactococcus lactis subsp. lactis Il1403 1115889 NP_268369.1 CDS ywjC NC_002662.1 2296386 2296484 R hypothetical protein complement(2296386..2296484) Lactococcus lactis subsp. lactis Il1403 1115890 NP_268370.1 CDS ywjD NC_002662.1 2296597 2296905 R PBSX(XRE) family of transcription regulators; transcriptional regulator complement(2296597..2296905) Lactococcus lactis subsp. lactis Il1403 1115891 NP_268371.1 CDS ywjE NC_002662.1 2297032 2297985 D hypothetical protein 2297032..2297985 Lactococcus lactis subsp. lactis Il1403 1115892 NP_268372.1 CDS ywjF NC_002662.1 2298168 2299049 R energy metabolism, amino acids and amines; 3-hydroxyisobutyrate dehydrogenase complement(2298168..2299049) Lactococcus lactis subsp. lactis Il1403 1115893 NP_268373.1 CDS ywjG NC_002662.1 2299091 2299411 R hypothetical protein complement(2299091..2299411) Lactococcus lactis subsp. lactis Il1403 1115894 NP_268374.1 CDS ywjH NC_002662.1 2299656 2300033 R hypothetical protein complement(2299656..2300033) Lactococcus lactis subsp. lactis Il1403 1115895 NP_268375.1 CDS yxaA NC_002662.1 2300033 2300884 R transport and binding protein; permease complement(2300033..2300884) Lactococcus lactis subsp. lactis Il1403 1115896 NP_268376.1 CDS yxaB NC_002662.1 2301070 2301249 D hypothetical protein 2301070..2301249 Lactococcus lactis subsp. lactis Il1403 1115897 NP_268377.1 CDS zwf NC_002662.1 2301320 2302831 D catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 2301320..2302831 Lactococcus lactis subsp. lactis Il1403 1115898 NP_268378.1 CDS yxaC NC_002662.1 2303023 2303550 R hypothetical protein complement(2303023..2303550) Lactococcus lactis subsp. lactis Il1403 1115899 NP_268379.1 CDS pspA NC_002662.1 2303692 2305140 D glucosyltransferase-S 2303692..2305140 Lactococcus lactis subsp. lactis Il1403 1115900 NP_268380.1 CDS pspB NC_002662.1 2305195 2306646 R glucosyltransferase-S complement(2305195..2306646) Lactococcus lactis subsp. lactis Il1403 1115901 NP_268381.1 CDS dnaJ NC_002662.1 2307231 2308370 R chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ complement(2307231..2308370) Lactococcus lactis subsp. lactis Il1403 1115902 NP_268382.1 CDS yxaF NC_002662.1 2308550 2309227 R hypothetical protein complement(2308550..2309227) Lactococcus lactis subsp. lactis Il1403 1115903 NP_268383.1 CDS racD NC_002662.1 2309217 2309939 R evidence experimental PMID:1907199; murein sacculus and peptidoglycan; provides D-aspartate, which plays a role of cross-bridge during peptidoglycan network formation; aspartate racemase complement(2309217..2309939) Lactococcus lactis subsp. lactis Il1403 1115904 NP_268384.1 CDS yxbA NC_002662.1 2309971 2311197 R probably carbamoylphosphate synthase large subunit, evidenced by COGnitor; hypothetical protein complement(2309971..2311197) Lactococcus lactis subsp. lactis Il1403 1115905 NP_268385.1 CDS asnH NC_002662.1 2311209 2313086 R aspartate family; asparagine synthetase complement(2311209..2313086) Lactococcus lactis subsp. lactis Il1403 1115906 NP_268386.1 CDS usp45 NC_002662.1 2313209 2314579 R evidence experimental PMID:2123812; secreted 45 kDa precursor; hypothetical protein complement(2313209..2314579) Lactococcus lactis subsp. lactis Il1403 1115907 NP_268387.1 CDS mreD NC_002662.1 2314683 2315210 R murein sacculus and peptidoglycan; involved in formation of the shape of the cell; may contribute to regulation of formation of penicillin-binding proteins; cell shape determining protein complement(2314683..2315210) Lactococcus lactis subsp. lactis Il1403 1115908 NP_268388.1 CDS mreC NC_002662.1 2315300 2316175 R in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC complement(2315300..2316175) Lactococcus lactis subsp. lactis Il1403 1115909 NP_268389.1 CDS yxbC NC_002662.1 2316468 2316908 D hypothetical protein 2316468..2316908 Lactococcus lactis subsp. lactis Il1403 1115910 NP_268390.1 CDS rpiA NC_002662.1 2316936 2317610 R Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A complement(2316936..2317610) Lactococcus lactis subsp. lactis Il1403 1115911 NP_268391.1 CDS rcfB NC_002662.1 2317694 2318380 R CRP/FNR family of transcription regulators; transcriptional regulator complement(2317694..2318380) Lactococcus lactis subsp. lactis Il1403 1115912 NP_268392.1 CDS yxbD NC_002662.1 2318463 2319683 R transport and binding protein; multidrug resistance; similar to quinolon resistance protein NorA from difference species; transporter complement(2318463..2319683) Lactococcus lactis subsp. lactis Il1403 1115913 NP_268393.1 CDS yxbE NC_002662.1 2319746 2320183 R hypothetical protein complement(2319746..2320183) Lactococcus lactis subsp. lactis Il1403 1115914 NP_268394.1 CDS yxbF NC_002662.1 2320203 2320406 R hypothetical protein complement(2320203..2320406) Lactococcus lactis subsp. lactis Il1403 1115915 NP_268395.1 CDS yxcA NC_002662.1 2320666 2324976 R similar to activator of (R)-2-hydroxyglutaryl-CoA dehydratase of Acidaminococcus fermentans; hypothetical protein complement(2320666..2324976) Lactococcus lactis subsp. lactis Il1403 1115916 NP_268396.1 CDS yxcB NC_002662.1 2325385 2325999 D belongs to TetR/AcrR family; transcriptional regulator 2325385..2325999 Lactococcus lactis subsp. lactis Il1403 1115917 NP_268397.1 CDS rsuA NC_002662.1 2326078 2326899 R RNA synthesis, modification, and DNA transcription; formation of pseudouridine from uracil-516 in 16S rRNA; family 1 of pseudouridine synthases and rluC; ribosomal small subunit pseudouridine synthase A complement(2326078..2326899) Lactococcus lactis subsp. lactis Il1403 1115918 NP_268398.1 CDS yxcD NC_002662.1 2326902 2327624 R similar to P50 adhesin of Mycoplasma hominisadhesins; probably a surface protein; hypothetical protein complement(2326902..2327624) Lactococcus lactis subsp. lactis Il1403 1115919 NP_268399.1 CDS trmE NC_002662.1 2327749 2329116 D in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 2327749..2329116 Lactococcus lactis subsp. lactis Il1403 1115920 NP_268400.1 CDS yxcE NC_002662.1 2329167 2329913 R hypothetical protein complement(2329167..2329913) Lactococcus lactis subsp. lactis Il1403 1115921 NP_268401.1 CDS recG NC_002662.1 2329913 2331913 R catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG complement(2329913..2331913) Lactococcus lactis subsp. lactis Il1403 1115922 NP_268402.1 CDS phnA NC_002662.1 2332051 2332395 R transport and binding protein, anions; alkylphosphonate uptake protein complement(2332051..2332395) Lactococcus lactis subsp. lactis Il1403 1115923 NP_268403.1 CDS gapB NC_002662.1 2332466 2333476 R glycolysis; glyceraldehyde 3-phosphate dehydrogenase complement(2332466..2333476) Lactococcus lactis subsp. lactis Il1403 1115924 NP_268404.1 CDS yxdB NC_002662.1 2333756 2334277 R hypothetical protein complement(2333756..2334277) Lactococcus lactis subsp. lactis Il1403 1115925 NP_268405.1 CDS yxdC NC_002662.1 2334405 2337098 D transort and binding protein; cations; cation-transporting ATPase 2334405..2337098 Lactococcus lactis subsp. lactis Il1403 1115926 NP_268406.1 CDS yxdD NC_002662.1 2337140 2337613 R general regulatory function; transcriptional regulator complement(2337140..2337613) Lactococcus lactis subsp. lactis Il1403 1115927 NP_268407.1 CDS yxdE NC_002662.1 2337792 2338811 D aerobic energy metabolism; similar to different oxidoreductases; oxidoreductase 2337792..2338811 Lactococcus lactis subsp. lactis Il1403 1115928 NP_268408.1 CDS yxdF NC_002662.1 2339285 2339818 D hypothetical protein 2339285..2339818 Lactococcus lactis subsp. lactis Il1403 1115929 NP_268409.1 CDS yxdG NC_002662.1 2339842 2340297 D transport and binding protein; transporter 2339842..2340297 Lactococcus lactis subsp. lactis Il1403 1115930 NP_268410.1 CDS rpsI NC_002662.1 2346315 2346707 R forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 complement(2346315..2346707) Lactococcus lactis subsp. lactis Il1403 1115931 NP_268411.1 CDS rplM NC_002662.1 2346727 2347173 R in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 complement(2346727..2347173) Lactococcus lactis subsp. lactis Il1403 1115932 NP_268412.1 CDS yxeA NC_002662.1 2347540 2348613 D hypothetical protein 2347540..2348613 Lactococcus lactis subsp. lactis Il1403 1115933 NP_268413.1 CDS yxeB NC_002662.1 2348622 2349293 D transport and binding protein; ABC transporter ATP-binding protein 2348622..2349293 Lactococcus lactis subsp. lactis Il1403 1115934 NP_268414.1 CDS rnhA NC_002662.1 2349438 2350316 D An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease HIII 2349438..2350316 Lactococcus lactis subsp. lactis Il1403 1115935 NP_268415.1 CDS sipL NC_002662.1 2350328 2350954 D protein and peptide secretion; signal peptidase I 2350328..2350954 Lactococcus lactis subsp. lactis Il1403 1115936 NP_268416.1 CDS purR NC_002662.1 2351004 2351819 R general regulatory function; pur operon repressor complement(2351004..2351819) Lactococcus lactis subsp. lactis Il1403 1115937 NP_268417.1 CDS fusA NC_002662.1 2352170 2354299 R EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G complement(2352170..2354299) Lactococcus lactis subsp. lactis Il1403 1115938 NP_268418.1 CDS rpsG NC_002662.1 2354564 2355031 R binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 complement(2354564..2355031) Lactococcus lactis subsp. lactis Il1403 1115939 NP_268419.1 CDS rpsL NC_002662.1 2355050 2355463 R interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 complement(2355050..2355463) Lactococcus lactis subsp. lactis Il1403 1115940 NP_268420.1 CDS dacA NC_002662.1 2355791 2357098 D murein sacculus and peptidoglycan; final stages in peptidoglycan synthesis; peptidase family S11, also know as D-alanyl-D-alanine carboxypeptidase 1 family; D-alanyl-D-alanine carboxypeptidase 2355791..2357098 Lactococcus lactis subsp. lactis Il1403 1115941 NP_268421.1 CDS yxfA NC_002662.1 2357172 2358059 R transport and binding protein; similar to several membrane proteins; transporter complement(2357172..2358059) Lactococcus lactis subsp. lactis Il1403 1115942 NP_268422.1 CDS yxfB NC_002662.1 2358185 2358775 R similar to YtqB of Bacillus subtilis; probably SAM-dependent methyltransferase, evidence by COGnitor; hypothetical protein complement(2358185..2358775) Lactococcus lactis subsp. lactis Il1403 1115943 NP_268423.1 CDS yxfC NC_002662.1 2358906 2359847 R hypothetical protein complement(2358906..2359847) Lactococcus lactis subsp. lactis Il1403 1115944 L200081 tRNA L200081 NC_002662.1 28196 28267 D tRNA-Glu 28196..28267 Lactococcus lactis subsp. lactis Il1403 1113538 L200082 tRNA L200082 NC_002662.1 28273 28362 D tRNA-Ser 28273..28362 Lactococcus lactis subsp. lactis Il1403 1113539 L200083 tRNA L200083 NC_002662.1 28373 28446 D tRNA-Met 28373..28446 Lactococcus lactis subsp. lactis Il1403 1113540 L200084 tRNA L200084 NC_002662.1 28451 28523 D tRNA-Phe 28451..28523 Lactococcus lactis subsp. lactis Il1403 1113541 L200085 tRNA L200085 NC_002662.1 28535 28605 D tRNA-Gly 28535..28605 Lactococcus lactis subsp. lactis Il1403 1113542 L200086 tRNA L200086 NC_002662.1 28620 28693 D tRNA-Ile 28620..28693 Lactococcus lactis subsp. lactis Il1403 1113543 L200087 tRNA L200087 NC_002662.1 28818 28891 D tRNA-Asn 28818..28891 Lactococcus lactis subsp. lactis Il1403 1113544 L200088 tRNA L200088 NC_002662.1 56361 56433 D tRNA-Lys 56361..56433 Lactococcus lactis subsp. lactis Il1403 1113545 L200141 tRNA L200141 NC_002662.1 123360 123448 R tRNA-Leu complement(123360..123448) Lactococcus lactis subsp. lactis Il1403 1113598 L200140 tRNA L200140 NC_002662.1 126511 126597 R tRNA-Ser complement(126511..126597) Lactococcus lactis subsp. lactis Il1403 1113597 L200139 tRNA L200139 NC_002662.1 155240 155312 R tRNA-Thr complement(155240..155312) Lactococcus lactis subsp. lactis Il1403 1113596 L200138 tRNA L200138 NC_002662.1 256042 256130 R tRNA-Leu complement(256042..256130) Lactococcus lactis subsp. lactis Il1403 1113595 L200137 tRNA L200137 NC_002662.1 275512 275599 R tRNA-Ser complement(275512..275599) Lactococcus lactis subsp. lactis Il1403 1113594 L200089 tRNA L200089 NC_002662.1 282716 282789 D tRNA-Arg 282716..282789 Lactococcus lactis subsp. lactis Il1403 1113546 L200090 tRNA L200090 NC_002662.1 283094 283167 D tRNA-Pro 283094..283167 Lactococcus lactis subsp. lactis Il1403 1113547 L200091 tRNA L200091 NC_002662.1 424317 424387 D tRNA-Cys 424317..424387 Lactococcus lactis subsp. lactis Il1403 1113548 L200092 tRNA L200092 NC_002662.1 447083 447156 D tRNA-Arg 447083..447156 Lactococcus lactis subsp. lactis Il1403 1113549 272623000018 tRNA 272623000018 NC_002662.1 483875 483935 D tRNA-OTHER 483875..483935 Lactococcus lactis subsp. lactis Il1403 L200093 tRNA L200093 NC_002662.1 517530 517603 D tRNA-Met 517530..517603 Lactococcus lactis subsp. lactis Il1403 1113550 L200094 tRNA L200094 NC_002662.1 539202 539274 D tRNA-Ala 539202..539274 Lactococcus lactis subsp. lactis Il1403 1113551 L200095 tRNA L200095 NC_002662.1 542516 542588 D tRNA-Val 542516..542588 Lactococcus lactis subsp. lactis Il1403 1113552 L200096 tRNA L200096 NC_002662.1 542618 542690 D tRNA-Asp 542618..542690 Lactococcus lactis subsp. lactis Il1403 1113553 L200097 tRNA L200097 NC_002662.1 542708 542780 D tRNA-Lys 542708..542780 Lactococcus lactis subsp. lactis Il1403 1113554 L200098 tRNA L200098 NC_002662.1 542789 542870 D tRNA-Leu 542789..542870 Lactococcus lactis subsp. lactis Il1403 1113555 L200099 tRNA L200099 NC_002662.1 542883 542955 D tRNA-Thr 542883..542955 Lactococcus lactis subsp. lactis Il1403 1113556 L200100 tRNA L200100 NC_002662.1 542981 543052 D tRNA-Gly 542981..543052 Lactococcus lactis subsp. lactis Il1403 1113557 L200101 tRNA L200101 NC_002662.1 543091 543164 D tRNA-Arg 543091..543164 Lactococcus lactis subsp. lactis Il1403 1113558 L200102 tRNA L200102 NC_002662.1 543170 543243 D tRNA-Pro 543170..543243 Lactococcus lactis subsp. lactis Il1403 1113559 L200103 tRNA L200103 NC_002662.1 543281 543354 D tRNA-Met 543281..543354 Lactococcus lactis subsp. lactis Il1403 1113560 L200104 tRNA L200104 NC_002662.1 543367 543440 D tRNA-Met 543367..543440 Lactococcus lactis subsp. lactis Il1403 1113561 L200105 tRNA L200105 NC_002662.1 543448 543520 D tRNA-Phe 543448..543520 Lactococcus lactis subsp. lactis Il1403 1113562 L200106 tRNA L200106 NC_002662.1 543531 543601 D tRNA-Gly 543531..543601 Lactococcus lactis subsp. lactis Il1403 1113563 L200107 tRNA L200107 NC_002662.1 543628 543701 D tRNA-Ile 543628..543701 Lactococcus lactis subsp. lactis Il1403 1113564 L200108 tRNA L200108 NC_002662.1 543744 543831 D tRNA-Ser 543744..543831 Lactococcus lactis subsp. lactis Il1403 1113565 L200109 tRNA L200109 NC_002662.1 617800 617871 D tRNA-Arg 617800..617871 Lactococcus lactis subsp. lactis Il1403 1113566 L200110 tRNA L200110 NC_002662.1 618494 618569 D tRNA-Lys 618494..618569 Lactococcus lactis subsp. lactis Il1403 1113567 L200136 tRNA L200136 NC_002662.1 1412349 1412438 R tRNA-Ser complement(1412349..1412438) Lactococcus lactis subsp. lactis Il1403 1113593 L15111 tRNA pi303 NC_002662.1 1415429 1415489 R tRNA-OTHER complement(1415429..1415489) Lactococcus lactis subsp. lactis Il1403 1115028 L200135 tRNA L200135 NC_002662.1 1690708 1690779 R tRNA-Gln complement(1690708..1690779) Lactococcus lactis subsp. lactis Il1403 1113592 L200111 tRNA L200111 NC_002662.1 1711201 1711273 D tRNA-Arg 1711201..1711273 Lactococcus lactis subsp. lactis Il1403 1113568 L200134 tRNA L200134 NC_002662.1 1980491 1980576 R tRNA-Leu complement(1980491..1980576) Lactococcus lactis subsp. lactis Il1403 1113591 L200133 tRNA L200133 NC_002662.1 1980612 1980683 R tRNA-Gly complement(1980612..1980683) Lactococcus lactis subsp. lactis Il1403 1113590 L200132 tRNA L200132 NC_002662.1 1980709 1980781 R tRNA-Thr complement(1980709..1980781) Lactococcus lactis subsp. lactis Il1403 1113589 L200131 tRNA L200131 NC_002662.1 1980794 1980875 R tRNA-Leu complement(1980794..1980875) Lactococcus lactis subsp. lactis Il1403 1113588 L200130 tRNA L200130 NC_002662.1 1980884 1980956 R tRNA-Lys complement(1980884..1980956) Lactococcus lactis subsp. lactis Il1403 1113587 L200129 tRNA L200129 NC_002662.1 1980974 1981046 R tRNA-Asp complement(1980974..1981046) Lactococcus lactis subsp. lactis Il1403 1113586 L200128 tRNA L200128 NC_002662.1 1981076 1981148 R tRNA-Val complement(1981076..1981148) Lactococcus lactis subsp. lactis Il1403 1113585 L200127 tRNA L200127 NC_002662.1 1984389 1984461 R tRNA-Ala complement(1984389..1984461) Lactococcus lactis subsp. lactis Il1403 1113584 L200126 tRNA L200126 NC_002662.1 2012538 2012621 R tRNA-Leu complement(2012538..2012621) Lactococcus lactis subsp. lactis Il1403 1113583 L200125 tRNA L200125 NC_002662.1 2151430 2151502 R tRNA-Thr complement(2151430..2151502) Lactococcus lactis subsp. lactis Il1403 1113582 L200124 tRNA L200124 NC_002662.1 2221450 2221522 R tRNA-Ala complement(2221450..2221522) Lactococcus lactis subsp. lactis Il1403 1113581 L200123 tRNA L200123 NC_002662.1 2263962 2264034 R tRNA-Ala complement(2263962..2264034) Lactococcus lactis subsp. lactis Il1403 1113580 L200122 tRNA L200122 NC_002662.1 2299369 2299451 R tRNA-Leu complement(2299369..2299451) Lactococcus lactis subsp. lactis Il1403 1113579 L200121 tRNA L200121 NC_002662.1 2340428 2340511 R tRNA-Leu complement(2340428..2340511) Lactococcus lactis subsp. lactis Il1403 1113578 L200120 tRNA L200120 NC_002662.1 2340524 2340595 R tRNA-Gln complement(2340524..2340595) Lactococcus lactis subsp. lactis Il1403 1113577 L200119 tRNA L200119 NC_002662.1 2340603 2340675 R tRNA-His complement(2340603..2340675) Lactococcus lactis subsp. lactis Il1403 1113576 L200118 tRNA L200118 NC_002662.1 2340686 2340756 R tRNA-Trp complement(2340686..2340756) Lactococcus lactis subsp. lactis Il1403 1113575 L200117 tRNA L200117 NC_002662.1 2340763 2340843 R tRNA-Tyr complement(2340763..2340843) Lactococcus lactis subsp. lactis Il1403 1113574 L200116 tRNA L200116 NC_002662.1 2340879 2340951 R tRNA-Val complement(2340879..2340951) Lactococcus lactis subsp. lactis Il1403 1113573 L200115 tRNA L200115 NC_002662.1 2344193 2344265 R tRNA-Ala complement(2344193..2344265) Lactococcus lactis subsp. lactis Il1403 1113572 L200114 tRNA L200114 NC_002662.1 2359943 2360016 R tRNA-Asn complement(2359943..2360016) Lactococcus lactis subsp. lactis Il1403 1113571 L200113 tRNA L200113 NC_002662.1 2360053 2360124 R tRNA-Glu complement(2360053..2360124) Lactococcus lactis subsp. lactis Il1403 1113570 L200112 tRNA L200112 NC_002662.1 2363372 2363444 R tRNA-Ala complement(2363372..2363444) Lactococcus lactis subsp. lactis Il1403 1113569 272623000001 rRNA 272623000001 NC_002662.1 28696 28811 D 5S ribosomal RNA 28696..28811 Lactococcus lactis subsp. lactis Il1403 L200142 rRNA L200142 NC_002662.1 537561 539108 D 16S ribosomal RNA 537561..539108 Lactococcus lactis subsp. lactis Il1403 1115945 L200143 rRNA L200143 NC_002662.1 539413 542313 D 23S ribosomal RNA 539413..542313 Lactococcus lactis subsp. lactis Il1403 1115946 L200144 rRNA L200144 NC_002662.1 542397 542512 D 5S ribosomal RNA 542397..542512 Lactococcus lactis subsp. lactis Il1403 1115947 L200145 rRNA L200145 NC_002662.1 1981152 1981267 R 5S ribosomal RNA complement(1981152..1981267) Lactococcus lactis subsp. lactis Il1403 1115948 L200146 rRNA L200146 NC_002662.1 1981351 1984250 R 23S ribosomal RNA complement(1981351..1984250) Lactococcus lactis subsp. lactis Il1403 1115949 L200147 rRNA L200147 NC_002662.1 1984555 1986102 R 16S ribosomal RNA complement(1984555..1986102) Lactococcus lactis subsp. lactis Il1403 1115950 L200148 rRNA L200148 NC_002662.1 2218214 2218329 R 5S ribosomal RNA complement(2218214..2218329) Lactococcus lactis subsp. lactis Il1403 1115951 L200149 rRNA L200149 NC_002662.1 2218413 2221311 R 23S ribosomal RNA complement(2218413..2221311) Lactococcus lactis subsp. lactis Il1403 1115952 L200150 rRNA L200150 NC_002662.1 2221616 2223163 R 16S ribosomal RNA complement(2221616..2223163) Lactococcus lactis subsp. lactis Il1403 1115953 L200151 rRNA L200151 NC_002662.1 2260725 2260840 R 5S ribosomal RNA complement(2260725..2260840) Lactococcus lactis subsp. lactis Il1403 1115954 L200152 rRNA L200152 NC_002662.1 2260924 2263823 R 23S ribosomal RNA complement(2260924..2263823) Lactococcus lactis subsp. lactis Il1403 1115955 L200153 rRNA L200153 NC_002662.1 2264128 2265675 R 16S ribosomal RNA complement(2264128..2265675) Lactococcus lactis subsp. lactis Il1403 1115956 L200154 rRNA L200154 NC_002662.1 2340955 2341070 R 5S ribosomal RNA complement(2340955..2341070) Lactococcus lactis subsp. lactis Il1403 1115957 L200155 rRNA L200155 NC_002662.1 2341154 2344054 R 23S ribosomal RNA complement(2341154..2344054) Lactococcus lactis subsp. lactis Il1403 1115958 L200156 rRNA L200156 NC_002662.1 2344359 2345906 R 16S ribosomal RNA complement(2344359..2345906) Lactococcus lactis subsp. lactis Il1403 1115959 L200157 rRNA L200157 NC_002662.1 2360134 2360249 R 5S ribosomal RNA complement(2360134..2360249) Lactococcus lactis subsp. lactis Il1403 1115960 L200158 rRNA L200158 NC_002662.1 2360333 2363233 R 23S ribosomal RNA complement(2360333..2363233) Lactococcus lactis subsp. lactis Il1403 1115961 L200159 rRNA L200159 NC_002662.1 2363538 2365085 R 16S ribosomal RNA complement(2363538..2365085) Lactococcus lactis subsp. lactis Il1403 1115962