-- dump date 20140619_125330 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_001031366.1 125622883 4798589 1..1365 1 NC_009004.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 1365 dnaA 4798589 dnaA Lactococcus lactis subsp. cremoris MG1363 chromosomal replication initiation protein YP_001031366.1 1 D 416870 CDS YP_001031367.1 125622884 4798369 1522..2664 1 NC_009004.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 2664 dnaN 4798369 dnaN Lactococcus lactis subsp. cremoris MG1363 DNA polymerase III subunit beta YP_001031367.1 1522 D 416870 CDS YP_001031368.1 125622885 4798396 2770..6069 1 NC_009004.1 ATP-dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent helicase and DNA-dependent ATPase; High confidence in function and specificity; ATP-dependent nuclease subunit B 6069 rexB 4798396 rexB Lactococcus lactis subsp. cremoris MG1363 ATP-dependent nuclease subunit B YP_001031368.1 2770 D 416870 CDS YP_001031369.1 125622886 4797078 6062..9673 1 NC_009004.1 UvrD/REP helicase; High confidence in function and specificity; ATP-dependent nuclease subunit A 9673 rexA 4797078 rexA Lactococcus lactis subsp. cremoris MG1363 ATP-dependent nuclease subunit A YP_001031369.1 6062 D 416870 CDS YP_001031370.1 125622887 4798206 9708..9908 1 NC_009004.1 Bacterial protein of unknown function DUF951; hypothetical protein 9908 4798206 llmg_0005 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031370.1 9708 D 416870 CDS YP_001031371.1 125622888 4796748 complement(9916..10473) 1 NC_009004.1 Lambda repressor-like, DNA-binding, Helix-turn- helix; HTH-type transcriptional regulator 10473 4796748 llmg_0006 Lactococcus lactis subsp. cremoris MG1363 HTH-type transcriptional regulator YP_001031371.1 9916 R 416870 CDS YP_001031372.1 125622889 4798155 10757..11872 1 NC_009004.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 11872 4798155 llmg_0007 Lactococcus lactis subsp. cremoris MG1363 GTP-dependent nucleic acid-binding protein EngD YP_001031372.1 10757 D 416870 CDS YP_001031373.1 125622890 4797060 11984..12307 1 NC_009004.1 DNA binding Helix-turn-helix motif; Conserved hypothetical protein; HTH-type transcriptional regulator 12307 4797060 llmg_0008 Lactococcus lactis subsp. cremoris MG1363 HTH-type transcriptional regulator YP_001031373.1 11984 D 416870 CDS YP_001031374.1 125622891 4798235 12720..13421 1 NC_009004.1 hypothetical protein 13421 4798235 llmg_0009 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031374.1 12720 D 416870 CDS YP_001031375.1 125622892 4799098 13521..13712 1 NC_009004.1 hypothetical protein 13712 4799098 llmg_0010 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031375.1 13521 D 416870 CDS YP_001031376.1 125622893 4797850 13947..14432 1 NC_009004.1 hypothetical protein 14432 4797850 llmg_0011 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031376.1 13947 D 416870 CDS YP_001031377.1 125622894 4797925 14436..15002 1 NC_009004.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 15002 pth 4797925 pth Lactococcus lactis subsp. cremoris MG1363 peptidyl-tRNA hydrolase YP_001031377.1 14436 D 416870 CDS YP_001031378.1 125622895 4797443 15003..18545 1 NC_009004.1 Transcription-repair coupling factor, CarD- like/TRCF domain; High confidence in function and specificity; transcription-repair coupling factor 18545 mfd 4797443 mfd Lactococcus lactis subsp. cremoris MG1363 transcription-repair coupling factor YP_001031378.1 15003 D 416870 CDS YP_001031379.1 125622896 4798909 18862..19131 1 NC_009004.1 RNA-binding S4; Conserved hypothetical protein; RNA binding protein 19131 4798909 llmg_0015 Lactococcus lactis subsp. cremoris MG1363 RNA binding protein YP_001031379.1 18862 D 416870 CDS YP_001031380.1 125622897 4796653 19162..19536 1 NC_009004.1 hypothetical protein 19536 4796653 llmg_0016 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031380.1 19162 D 416870 CDS YP_001031381.1 125622898 4796747 19536..19859 1 NC_009004.1 Nucleic acid-binding OB-fold, RNA binding S1 domain; Conserved hypothetical protein; hypothetical protein 19859 4796747 llmg_0017 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031381.1 19536 D 416870 CDS YP_001031382.1 125622899 4799110 20021..21337 1 NC_009004.1 COG: Beta-lactamase class A; Family membership; beta-lactamase A 21337 4799110 llmg_0018 Lactococcus lactis subsp. cremoris MG1363 beta-lactamase A YP_001031382.1 20021 D 416870 CDS YP_001031383.1 125622900 4796965 21334..22602 1 NC_009004.1 PP-loop family; High confidence in function and specificity; cell cycle protein mesJ 22602 mesJ 4796965 mesJ Lactococcus lactis subsp. cremoris MG1363 cell cycle protein mesJ YP_001031383.1 21334 D 416870 CDS YP_001031384.1 125622901 4797593 22583..23134 1 NC_009004.1 hypoxanthine phosphoribosyltransferase 23134 hpt 4797593 hpt Lactococcus lactis subsp. cremoris MG1363 hypoxanthine phosphoribosyltransferase YP_001031384.1 22583 D 416870 CDS YP_001031385.1 125622902 4798295 23340..25427 1 NC_009004.1 cell division protein 25427 ftsH 4798295 ftsH Lactococcus lactis subsp. cremoris MG1363 cell division protein YP_001031385.1 23340 D 416870 CDS YP_001031386.1 125622903 4799042 26494..28317 1 NC_009004.1 [KO:K02799 K02800], PTS system, mannitol-specific IIBC component (EIIBC-Mtl), Phosphotransferase system, EIIC; High confidence in function and specificity; PTS system mannitol-specific transporter subunit IIBC 28317 mtlA 4799042 mtlA Lactococcus lactis subsp. cremoris MG1363 PTS system mannitol-specific transporter subunit IIBC YP_001031386.1 26494 D 416870 CDS YP_001031387.1 125622904 4797439 28377..30311 1 NC_009004.1 PRD domain; High confidence in function and specificity; transcriptional regulator mtl operon mtlR 30311 mtlR 4797439 mtlR Lactococcus lactis subsp. cremoris MG1363 transcriptional regulator mtl operon mtlR YP_001031387.1 28377 D 416870 CDS YP_001031388.1 125622905 4797482 30358..30789 1 NC_009004.1 PTS system, mannitol-specific IIABC component (EIIABC-Mtl), Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; High confidence in function and specificity; PTS system mannitol-specific transporter subunit IIA 30789 mtlF 4797482 mtlF Lactococcus lactis subsp. cremoris MG1363 PTS system mannitol-specific transporter subunit IIA YP_001031388.1 30358 D 416870 CDS YP_001031389.1 125622906 4797451 30938..32104 1 NC_009004.1 Mannitol-1-phosphate 5-dehydrogenase; High confidence in function and specificity; mannitol-1-phosphate 5-dehydrogenase 32104 mtlD 4797451 mtlD Lactococcus lactis subsp. cremoris MG1363 mannitol-1-phosphate 5-dehydrogenase YP_001031389.1 30938 D 416870 CDS YP_001031390.1 125622907 4797446 complement(32974..33297) 1 NC_009004.1 hypothetical protein 33297 ps130 4797446 ps130 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031390.1 32974 R 416870 CDS YP_001031391.1 125622908 4798054 complement(33398..33778) 1 NC_009004.1 hypothetical protein 33778 ps129 4798054 ps129 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031391.1 33398 R 416870 CDS YP_001031392.1 125622909 4797973 complement(33806..34108) 1 NC_009004.1 nucleic acid binding motif, phage associated; hypothetical protein 34108 ps128 4797973 ps128 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031392.1 33806 R 416870 CDS YP_001031393.1 125622910 4797958 complement(34425..35006) 1 NC_009004.1 hypothetical protein 35006 ps127 4797958 ps127 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031393.1 34425 R 416870 CDS YP_001031394.1 125622911 4796891 complement(35242..36870) 1 NC_009004.1 Similar to ps105 from IL1403, Phage associated; Family membership; DNA primase 36870 ps126 4796891 ps126 Lactococcus lactis subsp. cremoris MG1363 DNA primase YP_001031394.1 35242 R 416870 CDS YP_001031395.1 125622912 4796946 complement(36881..37675) 1 NC_009004.1 phage DNA replication 37675 ps125 4796946 ps125 Lactococcus lactis subsp. cremoris MG1363 phage DNA replication YP_001031395.1 36881 R 416870 CDS YP_001031396.1 125622913 4798304 complement(37672..38007) 1 NC_009004.1 hypothetical protein 38007 ps124 4798304 ps124 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031396.1 37672 R 416870 CDS YP_001031397.1 125622914 4797243 complement(38004..38258) 1 NC_009004.1 hypothetical protein 38258 ps123 4797243 ps123 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031397.1 38004 R 416870 CDS YP_001031398.1 125622915 4798229 complement(38255..38494) 1 NC_009004.1 hypothetical protein 38494 ps122 4798229 ps122 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031398.1 38255 R 416870 CDS YP_001031399.1 125622916 4796976 complement(38536..38817) 1 NC_009004.1 DNA binding protein 38817 ps121 4796976 ps121 Lactococcus lactis subsp. cremoris MG1363 DNA binding protein YP_001031399.1 38536 R 416870 CDS YP_001031400.1 125622917 4798010 complement(38829..39254) 1 NC_009004.1 hypothetical protein 39254 ps120 4798010 ps120 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031400.1 38829 R 416870 CDS YP_001031401.1 125622918 4796936 complement(39259..39453) 1 NC_009004.1 Similar to ps113 of IL1403, Protein of unknown function (DUF1655), Phage associated; hypothetical protein 39453 ps119 4796936 ps119 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031401.1 39259 R 416870 CDS YP_001031402.1 125622919 4796961 complement(39569..39754) 1 NC_009004.1 Lambda repressor-like, DNA-binding, Helix-turn- helix; hypothetical protein 39754 ps118 4796961 ps118 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031402.1 39569 R 416870 CDS YP_001031403.1 125622920 4796925 39837..40163 1 NC_009004.1 hypothetical protein 40163 ps117 4796925 ps117 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031403.1 39837 D 416870 CDS YP_001031404.1 125622921 4796585 complement(40519..40734) 1 NC_009004.1 Lambda repressor-like, DNA-binding; phage repressor 40734 ps116 4796585 ps116 Lactococcus lactis subsp. cremoris MG1363 phage repressor YP_001031404.1 40519 R 416870 CDS YP_001031405.1 125622922 4796897 40860..41282 1 NC_009004.1 Family membership; phage repressor 41282 ps115 4796897 ps115 Lactococcus lactis subsp. cremoris MG1363 phage repressor YP_001031405.1 40860 D 416870 CDS YP_001031406.1 125622923 4796889 41312..41866 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 41866 ps114 4796889 ps114 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031406.1 41312 D 416870 CDS YP_001031407.1 125622924 4798656 41977..42207 1 NC_009004.1 Similar to ps117 from IL1403; hypothetical protein 42207 ps113 4798656 ps113 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031407.1 41977 D 416870 CDS YP_001031408.1 125622925 4796923 42280..42474 1 NC_009004.1 nucleic acid binding motif; hypothetical protein 42474 ps112 4796923 ps112 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031408.1 42280 D 416870 CDS YP_001031409.1 125622926 4796934 43098..44423 1 NC_009004.1 hypothetical protein 44423 ps111 4796934 ps111 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031409.1 43098 D 416870 CDS YP_001031410.1 125622927 4798167 44505..44711 1 NC_009004.1 hypothetical protein 44711 ps110 4798167 ps110 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031410.1 44505 D 416870 CDS YP_001031411.1 125622928 4796706 45201..45443 1 NC_009004.1 Similar to ps119 from IL1403; hypothetical protein 45443 ps109 4796706 ps109 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031411.1 45201 D 416870 CDS YP_001031412.1 125622929 4796604 45579..45803 1 NC_009004.1 Similar to ps120 from IL1403; Ps108 protein 45803 ps108 4796604 ps108 Lactococcus lactis subsp. cremoris MG1363 Ps108 protein YP_001031412.1 45579 D 416870 CDS YP_001031413.1 125622930 4797130 46467..47690 1 NC_009004.1 Conserved hypothetical protein; transposase for insertion sequence element IS712A 47690 tnp712 4797130 tnp712 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS712A YP_001031413.1 46467 D 416870 CDS YP_001031414.1 125622931 4798172 47702..48460 1 NC_009004.1 IstB-like ATP-binding protein; Conserved hypothetical protein; transposase helper protein for IS712A 48460 4798172 llmg_0050 Lactococcus lactis subsp. cremoris MG1363 transposase helper protein for IS712A YP_001031414.1 47702 D 416870 CDS YP_001031415.1 125622932 4796599 48562..48888 1 NC_009004.1 hypothetical protein 48888 ps105 4796599 ps105 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031415.1 48562 D 416870 CDS YP_001031416.1 125622933 4796690 49396..49533 1 NC_009004.1 phage protein; hypothetical protein 49533 ps104 4796690 ps104 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031416.1 49396 D 416870 CDS YP_001031417.1 125622934 4796705 49622..49786 1 NC_009004.1 hypothetical protein 49786 ps103 4796705 ps103 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031417.1 49622 D 416870 CDS YP_001031418.1 125622935 4797146 49908..50213 1 NC_009004.1 Similar to lciA, Lactococcin A immunity protein; Conserved hypothetical protein; hypothetical protein 50213 ps102 4797146 ps102 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031418.1 49908 D 416870 CDS YP_001031419.1 125622936 4797037 50463..51647 1 NC_009004.1 DNA breaking-rejoining enzyme, catalytic core, Tyrosine recombinase xerD; Conserved hypothetical protein; phage integrase 51647 ps101 4797037 ps101 Lactococcus lactis subsp. cremoris MG1363 phage integrase YP_001031419.1 50463 D 416870 CDS YP_001031420.1 125622937 4796957 complement(52156..52938) 1 NC_009004.1 Bacterial protein of unknown function DUF915; Family membership; hypothetical protein 52938 4796957 llmg_0056 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031420.1 52156 R 416870 CDS YP_001031421.1 125622938 4796648 53631..53996 1 NC_009004.1 hypothetical protein 53996 4796648 llmg_0057 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031421.1 53631 D 416870 CDS YP_001031422.1 125622939 4798185 54401..54892 1 NC_009004.1 hypothetical protein 54892 4798185 llmg_0059 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031422.1 54401 D 416870 CDS YP_001031423.1 125622940 4796637 55405..55563 1 NC_009004.1 hypothetical protein 55563 4796637 llmg_0060 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031423.1 55405 D 416870 CDS YP_001031424.1 125622941 4799096 55905..56453 1 NC_009004.1 GCN5-related N-acetyltransferase; Function unclear; acetyltransferase 56453 4799096 llmg_0061 Lactococcus lactis subsp. cremoris MG1363 acetyltransferase YP_001031424.1 55905 D 416870 CDS YP_001031425.1 125622942 4798950 56574..56777 1 NC_009004.1 hypothetical protein 56777 4798950 llmg_0062 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031425.1 56574 D 416870 CDS YP_001031426.1 125622943 4798957 complement(56870..58492) 1 NC_009004.1 Sulfate transporter family, sulP: sulfate permease; Family membership; sulfate transporter 58492 4798957 llmg_0063 Lactococcus lactis subsp. cremoris MG1363 sulfate transporter YP_001031426.1 56870 R 416870 CDS YP_001031427.1 125622944 4798783 complement(58702..59877) 1 NC_009004.1 High confidence in function and specificity; transposase for insertion sequence element IS905A 59877 tnp905 4798783 tnp905 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS905A YP_001031427.1 58702 R 416870 CDS YP_001031428.1 125622945 4798247 60023..60544 1 NC_009004.1 Amino-acid acetyltransferase, GCN5-related N- acetyltransferase; Family membership; GNAT family acetyltransferase 60544 4798247 llmg_0065 Lactococcus lactis subsp. cremoris MG1363 GNAT family acetyltransferase YP_001031428.1 60023 D 416870 CDS YP_001031429.1 125622946 4796883 60873..62048 1 NC_009004.1 catalyzes the transamination of the aromatic amino acid forming a ketoacid; first step in aromatic amino acid degradation in lactococci; aromatic amino acid aminotransferase 62048 araT 4796883 araT Lactococcus lactis subsp. cremoris MG1363 aromatic amino acid aminotransferase YP_001031429.1 60873 D 416870 CDS YP_001031430.1 125622947 4797012 62146..62901 1 NC_009004.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 62901 recO 4797012 recO Lactococcus lactis subsp. cremoris MG1363 DNA repair protein RecO YP_001031430.1 62146 D 416870 CDS YP_001031431.1 125622948 4798205 63015..63896 1 NC_009004.1 RGG_Cterm: transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Conserved hypothetical protein; HTH-type transcriptional regulator 63896 4798205 llmg_0069 Lactococcus lactis subsp. cremoris MG1363 HTH-type transcriptional regulator YP_001031431.1 63015 D 416870 CDS YP_001031432.1 125622949 4797031 64007..65242 1 NC_009004.1 Major facilitator superfamily MFS_1; Family membership; permease 65242 4797031 llmg_0070 Lactococcus lactis subsp. cremoris MG1363 permease YP_001031432.1 64007 D 416870 CDS YP_001031433.1 125622950 4798159 complement(65273..66691) 1 NC_009004.1 E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 66691 pdhD 4798159 pdhD Lactococcus lactis subsp. cremoris MG1363 dihydrolipoamide dehydrogenase YP_001031433.1 65273 R 416870 CDS YP_001031434.1 125622951 4798127 complement(66910..68502) 1 NC_009004.1 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, PDHac_trf_long: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; High confidence in function and specificity; pyruvate dehydrogenase complex E2 component 68502 pdhC 4798127 pdhC Lactococcus lactis subsp. cremoris MG1363 pyruvate dehydrogenase complex E2 component YP_001031434.1 66910 R 416870 CDS YP_001031435.1 125622952 4798128 complement(68495..69475) 1 NC_009004.1 1-deoxy-D-xylulose-5-phosphate synthase (DXP synthase); High confidence in function and specificity; pyruvate dehydrogenase E1 component beta subunit 69475 pdhB 4798128 pdhB Lactococcus lactis subsp. cremoris MG1363 pyruvate dehydrogenase E1 component beta subunit YP_001031435.1 68495 R 416870 CDS YP_001031436.1 125622953 4798130 complement(69478..70602) 1 NC_009004.1 pyruvate dehydrogenase E1 component alpha subunit 70602 pdhA 4798130 pdhA Lactococcus lactis subsp. cremoris MG1363 pyruvate dehydrogenase E1 component alpha subunit YP_001031436.1 69478 R 416870 CDS YP_001031437.1 125622954 4798148 complement(70691..71692) 1 NC_009004.1 Lipoyltransferase and lipoate-protein ligase; High confidence in function and specificity; lipoate-protein ligase 71692 lplL 4798148 lplL Lactococcus lactis subsp. cremoris MG1363 lipoate-protein ligase YP_001031437.1 70691 R 416870 CDS YP_001031438.1 125622955 4796665 complement(71885..72739) 1 NC_009004.1 High confidence in function and specificity; glycerophosphodiester phosphodiesterase 72739 4796665 llmg_0076 Lactococcus lactis subsp. cremoris MG1363 glycerophosphodiester phosphodiesterase YP_001031438.1 71885 R 416870 CDS YP_001031439.1 125622956 4797453 complement(72818..73468) 1 NC_009004.1 Metal-dependent phosphohydrolase, HD region; Family membership; phosphohydrolase 73468 4797453 llmg_0077 Lactococcus lactis subsp. cremoris MG1363 phosphohydrolase YP_001031439.1 72818 R 416870 CDS YP_001031440.1 125622957 4797069 complement(73518..73844) 1 NC_009004.1 hypothetical protein 73844 4797069 llmg_0078 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031440.1 73518 R 416870 CDS YP_001031441.1 125622958 4796978 complement(73937..74962) 1 NC_009004.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase II 74962 trpS 4796978 trpS Lactococcus lactis subsp. cremoris MG1363 tryptophanyl-tRNA synthetase II YP_001031441.1 73937 R 416870 CDS YP_001031442.1 125622959 4798232 75461..75898 1 NC_009004.1 OsmC-like protein; High confidence in function and specificity; osmotically inducible protein C 75898 osmC 4798232 osmC Lactococcus lactis subsp. cremoris MG1363 osmotically inducible protein C YP_001031442.1 75461 D 416870 CDS YP_001031443.1 125622960 4799083 76060..77373 1 NC_009004.1 Amino acid permease-associated region; Function unclear; amino-acid permease 77373 4799083 llmg_0081 Lactococcus lactis subsp. cremoris MG1363 amino-acid permease YP_001031443.1 76060 D 416870 CDS YP_001031444.1 125622961 4798306 77433..77783 1 NC_009004.1 hypothetical protein 77783 4798306 llmg_0082 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031444.1 77433 D 416870 CDS YP_001031445.1 125622962 4798294 complement(77843..78838) 1 NC_009004.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 78838 plsX 4798294 plsX Lactococcus lactis subsp. cremoris MG1363 glycerol-3-phosphate acyltransferase PlsX YP_001031445.1 77843 R 416870 CDS YP_001031446.1 125622963 4797072 complement(78941..79753) 1 NC_009004.1 Cof-subfamily: Cof-like hydrolase; Family membership; hydrolase 79753 4797072 llmg_0084 Lactococcus lactis subsp. cremoris MG1363 hydrolase YP_001031446.1 78941 R 416870 CDS YP_001031447.1 125622964 4798289 complement(80129..81766) 1 NC_009004.1 ABC transporter related; Specificity unclear; ABC transporter ATP-binding protein 81766 4798289 llmg_0085 Lactococcus lactis subsp. cremoris MG1363 ABC transporter ATP-binding protein YP_001031447.1 80129 R 416870 CDS YP_001031448.1 125622965 4796907 82266..82520 1 NC_009004.1 yiaA/B two helix domain; Conserved hypothetical protein; hypothetical protein 82520 4796907 llmg_0086 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031448.1 82266 D 416870 CDS YP_001031449.1 125622966 4797356 complement(82640..83464) 1 NC_009004.1 homology to 3-oxoacyl-[acyl-carrier-protein] reductase, Short-chain dehydrogenase/reductase SDR; Function unclear; short-chain type dehydrogenase 83464 4797356 llmg_0087 Lactococcus lactis subsp. cremoris MG1363 short-chain type dehydrogenase YP_001031449.1 82640 R 416870 CDS YP_001031450.1 125622967 4797349 83680..84249 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 84249 4797349 llmg_0088 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031450.1 83680 D 416870 CDS YP_001031451.1 125622968 4797521 complement(85125..85706) 1 NC_009004.1 High confidence in function and specificity; HTH-type transcriptional regulator 85706 4797521 llmg_0089 Lactococcus lactis subsp. cremoris MG1363 HTH-type transcriptional regulator YP_001031451.1 85125 R 416870 CDS YP_001031452.1 125622969 4797318 complement(85894..86376) 1 NC_009004.1 Region start changed from 86382 to 86376 (-6 bases); hypothetical protein 86376 4797318 llmg_0090 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031452.1 85894 R 416870 CDS YP_001031453.1 125622970 4797283 complement(86633..87913) 1 NC_009004.1 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase, Cystathionine beta-lyases/cystathionine gamma-synthases; High confidence in function and specificity; O-acetylhomoserine sulfhydrylase 87913 cysD 4797283 cysD Lactococcus lactis subsp. cremoris MG1363 O-acetylhomoserine sulfhydrylase YP_001031453.1 86633 R 416870 CDS YP_001031454.1 125622971 4798863 complement(88166..88999) 1 NC_009004.1 Short-chain dehydrogenase/reductase SDR, homology to 3-oxoacyl-[acyl-carrier-protein] reductase; Function unclear; short-chain type dehydrogenase 88999 4798863 llmg_0092 Lactococcus lactis subsp. cremoris MG1363 short-chain type dehydrogenase YP_001031454.1 88166 R 416870 CDS YP_001031455.1 125622972 4797265 89403..89870 1 NC_009004.1 Universal stress protein family; Conserved hypothetical protein; hypothetical protein 89870 4797265 llmg_0093 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031455.1 89403 D 416870 CDS YP_001031456.1 125622973 4797253 89996..90193 1 NC_009004.1 hypothetical protein 90193 4797253 llmg_0094 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031456.1 89996 D 416870 CDS YP_001031457.1 125622974 4797358 90229..90849 1 NC_009004.1 Esterase/lipase/thioesterase; esterase 90849 4797358 llmg_0095 Lactococcus lactis subsp. cremoris MG1363 esterase YP_001031457.1 90229 D 416870 CDS YP_001031458.1 125622975 4797820 90917..92086 1 NC_009004.1 Family membership; glyoxylase 92086 4797820 llmg_0096 Lactococcus lactis subsp. cremoris MG1363 glyoxylase YP_001031458.1 90917 D 416870 CDS YP_001031459.1 125622976 4798000 92097..92687 1 NC_009004.1 contains FMN-binding split barrel domain; Function unclear; flavoprotein oxygenase 92687 4798000 llmg_0097 Lactococcus lactis subsp. cremoris MG1363 flavoprotein oxygenase YP_001031459.1 92097 D 416870 CDS YP_001031460.1 125622977 4798430 complement(92769..92918) 1 NC_009004.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 92918 rpmG 4798430 rpmG Lactococcus lactis subsp. cremoris MG1363 50S ribosomal protein L33 YP_001031460.1 92769 R 416870 CDS YP_001031461.1 125622978 4799008 complement(92948..93121) 1 NC_009004.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 93121 rpmF 4799008 rpmF Lactococcus lactis subsp. cremoris MG1363 50S ribosomal protein L32 YP_001031461.1 92948 R 416870 CDS YP_001031462.1 125622979 4799007 93484..95265 1 NC_009004.1 High confidence in function and specificity; cation-transporting ATPase 95265 cadA 4799007 cadA Lactococcus lactis subsp. cremoris MG1363 cation-transporting ATPase YP_001031462.1 93484 D 416870 CDS YP_001031463.1 125622980 4797729 95452..96300 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 96300 4797729 llmg_0101 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031463.1 95452 D 416870 CDS YP_001031464.1 125622981 4798323 complement(96310..97095) 1 NC_009004.1 ParB-like partition protein, ParB-like nuclease domain; High confidence in function and specificity; chromosome partitioning protein parA 97095 parA 4798323 parA Lactococcus lactis subsp. cremoris MG1363 chromosome partitioning protein parA YP_001031464.1 96310 R 416870 CDS YP_001031465.1 125622982 4798774 complement(97150..98409) 1 NC_009004.1 High confidence in function and specificity; recombination factor protein RarA 98409 cshA 4798774 cshA Lactococcus lactis subsp. cremoris MG1363 recombination factor protein RarA YP_001031465.1 97150 R 416870 CDS YP_001031466.1 125622983 4798818 complement(98453..98995) 1 NC_009004.1 GCN5-related N-acetyltransferase, Acetyltransferase (GNAT) family; High confidence in function and specificity; acetyltransferase 98995 4798818 llmg_0104 Lactococcus lactis subsp. cremoris MG1363 acetyltransferase YP_001031466.1 98453 R 416870 CDS YP_001031467.1 125622984 4797804 99114..99581 1 NC_009004.1 hypothetical protein 99581 4797804 llmg_0105 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031467.1 99114 D 416870 CDS YP_001031468.1 125622985 4798069 99611..101164 1 NC_009004.1 ABC transporter related; Family membership; ABC transporter ATP-binding protein 101164 4798069 llmg_0106 Lactococcus lactis subsp. cremoris MG1363 ABC transporter ATP-binding protein YP_001031468.1 99611 D 416870 CDS YP_001031469.1 125622986 4796797 101239..101523 1 NC_009004.1 hypothetical protein 101523 4796797 llmg_0107 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031469.1 101239 D 416870 CDS YP_001031470.1 125622987 4797514 101605..102297 1 NC_009004.1 S-adenosylmethionine-dependent methyltransferase, SAM (and some other nucleotide) binding motif; Family membership; S-adenosylmethionine-dependent methyltransferase 102297 4797514 llmg_0108 Lactococcus lactis subsp. cremoris MG1363 S-adenosylmethionine-dependent methyltransferase YP_001031470.1 101605 D 416870 CDS YP_001031471.1 125622988 4797501 102281..102772 1 NC_009004.1 hypothetical protein 102772 4797501 llmg_0109 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031471.1 102281 D 416870 CDS YP_001031472.1 125622989 4797609 102785..103738 1 NC_009004.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 103738 prmA 4797609 prmA Lactococcus lactis subsp. cremoris MG1363 50S ribosomal protein L11 methyltransferase YP_001031472.1 102785 D 416870 CDS YP_001031473.1 125622990 4798532 103858..104610 1 NC_009004.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 104610 4798532 llmg_0111 Lactococcus lactis subsp. cremoris MG1363 16S ribosomal RNA methyltransferase RsmE YP_001031473.1 103858 D 416870 CDS YP_001031474.1 125622991 4797449 104640..105596 1 NC_009004.1 Polysaccharide deacetylase, Signal peptide and one TMH; Family membership; xylanase/chitin deacetylase 105596 4797449 llmg_0112 Lactococcus lactis subsp. cremoris MG1363 xylanase/chitin deacetylase YP_001031474.1 104640 D 416870 CDS YP_001031475.1 125622992 4797906 105797..108019 1 NC_009004.1 guanosine-3',5'-bis(diphosphate) 3'- pyrophosphohydrolase ((ppGpp)ase) (Penta-phosphate guanosine-3'- pyrophosphohydrolase); High confidence in function and specificity; GTP pyrophosphokinase 108019 relA 4797906 relA Lactococcus lactis subsp. cremoris MG1363 GTP pyrophosphokinase YP_001031475.1 105797 D 416870 CDS YP_001031476.1 125622993 4797043 complement(108034..108969) 1 NC_009004.1 Glycosyl transferase, family 2; Function unclear; glycosyl transferase family protein 108969 4797043 llmg_0114 Lactococcus lactis subsp. cremoris MG1363 glycosyl transferase family protein YP_001031476.1 108034 R 416870 CDS YP_001031477.1 125622994 4798597 109228..109683 1 NC_009004.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 109683 dtd 4798597 dtd Lactococcus lactis subsp. cremoris MG1363 D-tyrosyl-tRNA(Tyr) deacylase YP_001031477.1 109228 D 416870 CDS YP_001031478.1 125622995 4798384 109676..110680 1 NC_009004.1 Protein of unknown function DUF1211; hypothetical protein 110680 4798384 llmg_0116 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031478.1 109676 D 416870 CDS YP_001031479.1 125622996 4798739 110683..111306 1 NC_009004.1 hydrolase (HAD superfamily) (PFAM), Haloacid dehalogenase-like hydrolase; Conserved hypothetical protein; hypothetical protein 111306 4798739 llmg_0117 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031479.1 110683 D 416870 CDS YP_001031480.1 125622997 4797605 111440..112837 1 NC_009004.1 Amino acid permease-associated region, COG: Amino acid transporters, PFAM: Amino acid permease, 2A0306: amino acid transporter; Conserved hypothetical protein; amino-acid transporter 112837 ctrA 4797605 ctrA Lactococcus lactis subsp. cremoris MG1363 amino-acid transporter YP_001031480.1 111440 D 416870 CDS YP_001031481.1 125622998 4798841 112986..113648 1 NC_009004.1 acyltransferase 113648 4798841 llmg_0119 Lactococcus lactis subsp. cremoris MG1363 acyltransferase YP_001031481.1 112986 D 416870 CDS YP_001031482.1 125622999 4798609 complement(113679..114197) 1 NC_009004.1 Bacterial regulatory protein, MarR; Conserved hypothetical protein; MarR family transcriptional regulator 114197 rmaD 4798609 rmaD Lactococcus lactis subsp. cremoris MG1363 MarR family transcriptional regulator YP_001031482.1 113679 R 416870 CDS YP_001031483.1 125623000 4797590 114407..114697 1 NC_009004.1 transposase helper protein for IS904; hypothetical protein 114697 4797590 llmg_0121 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031483.1 114407 D 416870 CDS YP_001031484.1 125623001 4798443 114793..115554 1 NC_009004.1 Integrase, catalytic region; Conserved hypothetical protein; transposase for insertion sequence element IS904A 115554 tnp904 4798443 tnp904 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS904A YP_001031484.1 114793 D 416870 CDS YP_001031485.1 125623002 4798339 complement(115603..116247) 1 NC_009004.1 acyl carrier protein phosphodiesterase, fatty acid and phospholipid metabolism; High confidence in function and specificity; acyl carrier protein 116247 acpD 4798339 acpD Lactococcus lactis subsp. cremoris MG1363 acyl carrier protein YP_001031485.1 115603 R 416870 CDS YP_001031486.1 125623003 4798902 116422..119019 1 NC_009004.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 119019 secA 4798902 secA Lactococcus lactis subsp. cremoris MG1363 preprotein translocase subunit SecA YP_001031486.1 116422 D 416870 CDS YP_001031487.1 125623004 4797238 119149..120186 1 NC_009004.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 120186 aroF 4797238 aroF Lactococcus lactis subsp. cremoris MG1363 phospho-2-dehydro-3-deoxyheptonate aldolase YP_001031487.1 119149 D 416870 CDS YP_001031488.1 125623005 4798281 120435..120701 1 NC_009004.1 Phosphocarrier protein HPr (Histidine-containing protein)., PTS HPr component phosphorylation site, PTS_HPr_family: phosphocarrier protein HPr; High confidence in function and specificity; phosphocarrier protein HPr 120701 ptsH 4798281 ptsH Lactococcus lactis subsp. cremoris MG1363 phosphocarrier protein HPr YP_001031488.1 120435 D 416870 CDS YP_001031489.1 125623006 4797692 120704..122431 1 NC_009004.1 Phosphoenolpyruvate-protein phosphotransferase , Phosphotransferase system, enzyme I, PEP-utilising enzyme, TIM barrel domain, PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase; High confidence in function and specificity; phosphoenolpyruvate-protein phosphotransferase 122431 ptsI 4797692 ptsI Lactococcus lactis subsp. cremoris MG1363 phosphoenolpyruvate-protein phosphotransferase YP_001031489.1 120704 D 416870 CDS YP_001031490.1 125623007 4797702 complement(123002..123301) 1 NC_009004.1 hypothetical protein 123301 4797702 llmg_0128 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031490.1 123002 R 416870 CDS YP_001031491.1 125623008 4796836 123407..123694 1 NC_009004.1 hypothetical protein 123694 4796836 llmg_0129 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031491.1 123407 D 416870 CDS YP_001031492.1 125623009 4796573 complement(123974..124918) 1 NC_009004.1 Esterase/lipase/thioesterase; Conserved hypothetical protein; hypothetical protein 124918 4796573 llmg_0130 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031492.1 123974 R 416870 CDS YP_001031493.1 125623010 4797180 125070..126458 1 NC_009004.1 hypothetical protein 126458 4797180 llmg_0131 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031493.1 125070 D 416870 CDS YP_001031494.1 125623011 4798389 126644..126964 1 NC_009004.1 EmrE protein (Methyl viologen resistance protein C) , (Ethidium resistance protein); Specificity unclear; small multidrug resistance protein 126964 sugE 4798389 sugE Lactococcus lactis subsp. cremoris MG1363 small multidrug resistance protein YP_001031494.1 126644 D 416870 CDS YP_001031495.1 125623012 4798599 127087..128250 1 NC_009004.1 Multidrug resistance protein 1 (Multidrug-efflux transporter 1)., General substrate transporter Major Facilitator Superfamily, 2_A_01_02: Multidrug resistance protein; High confidence in function and specificity; multidrug resistance protein 128250 blt 4798599 blt Lactococcus lactis subsp. cremoris MG1363 multidrug resistance protein YP_001031495.1 127087 D 416870 CDS YP_001031496.1 125623013 4798850 128554..129504 1 NC_009004.1 Glycosyl transferase, family 2, Bactoprenol glucosyl transferase; High confidence in function and specificity; bactoprenol glucosyl transferase 129504 4798850 llmg_0134 Lactococcus lactis subsp. cremoris MG1363 bactoprenol glucosyl transferase YP_001031496.1 128554 D 416870 CDS YP_001031497.1 125623014 4798373 129488..130723 1 NC_009004.1 predicted transmembrane protein, multiple transmembrane segments; hypothetical protein 130723 4798373 llmg_0135 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031497.1 129488 D 416870 CDS YP_001031498.1 125623015 4798368 131117..131638 1 NC_009004.1 ATP-binding region, ATPase-like; Conserved hypothetical protein; sensor protein kinase 131638 4798368 llmg_0136 Lactococcus lactis subsp. cremoris MG1363 sensor protein kinase YP_001031498.1 131117 D 416870 CDS YP_001031499.1 125623016 4798882 131705..133078 1 NC_009004.1 Permeases of the major facilitator superfamily, von Willebrand factor, type A; permease 133078 4798882 llmg_0137 Lactococcus lactis subsp. cremoris MG1363 permease YP_001031499.1 131705 D 416870 CDS YP_001031500.1 125623017 4796764 134045..135241 1 NC_009004.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase 135241 argG 4796764 argG Lactococcus lactis subsp. cremoris MG1363 argininosuccinate synthase YP_001031500.1 134045 D 416870 CDS YP_001031501.1 125623018 4796894 135270..136649 1 NC_009004.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 136649 argH 4796894 argH Lactococcus lactis subsp. cremoris MG1363 argininosuccinate lyase YP_001031501.1 135270 D 416870 CDS YP_001031502.1 125623019 4799106 complement(136666..137811) 1 NC_009004.1 Multidrug resistance protein, Integral membrane protein; Conserved hypothetical protein; multidrug resistance efflux pump 137811 pmrB 4799106 pmrB Lactococcus lactis subsp. cremoris MG1363 multidrug resistance efflux pump YP_001031502.1 136666 R 416870 CDS YP_001031503.1 125623020 4797842 138054..138629 1 NC_009004.1 Tetracyclin repressor-like, C-terminal; Conserved hypothetical protein; transcriptional regulator 138629 4797842 llmg_0141 Lactococcus lactis subsp. cremoris MG1363 transcriptional regulator YP_001031503.1 138054 D 416870 CDS YP_001031504.1 125623021 4798919 138786..139139 1 NC_009004.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 139139 rnpA 4798919 rnpA Lactococcus lactis subsp. cremoris MG1363 ribonuclease P YP_001031504.1 138786 D 416870 CDS YP_001031505.1 125623022 4798421 139136..139945 1 NC_009004.1 Region start changed from 139163 to 139136 (27 bases); preprotein translocase subunit 139945 4798421 llmg_0143 Lactococcus lactis subsp. cremoris MG1363 preprotein translocase subunit YP_001031505.1 139136 D 416870 CDS YP_001031506.1 125623023 4798762 140033..140947 1 NC_009004.1 Single-stranded nucleic acid binding , Domain R3H and KH; Conserved hypothetical protein; ORF1; hypothetical protein 140947 4798762 llmg_0144 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031506.1 140033 D 416870 CDS YP_001031507.1 125623024 4798551 141079..141213 1 NC_009004.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 141213 rpmH 4798551 rpmH Lactococcus lactis subsp. cremoris MG1363 50S ribosomal protein L34 YP_001031507.1 141079 D 416870 CDS YP_001031508.1 125623025 4798806 141388..142299 1 NC_009004.1 Aldo/keto reductase, Aldo/keto reductase; High confidence in function and specificity; aryl-alcohol dehydrogenase 142299 4798806 llmg_0146 Lactococcus lactis subsp. cremoris MG1363 aryl-alcohol dehydrogenase YP_001031508.1 141388 D 416870 CDS YP_001031509.1 125623026 4796824 142360..142620 1 NC_009004.1 lambda repressor-like, DNA-binding 142620 4796824 llmg_0147 Lactococcus lactis subsp. cremoris MG1363 lambda repressor-like, DNA-binding YP_001031509.1 142360 D 416870 CDS YP_001031510.1 125623027 4796587 142809..143009 1 NC_009004.1 hypothetical protein 143009 4796587 llmg_0148 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031510.1 142809 D 416870 CDS YP_001031511.1 125623028 4797836 143092..143772 1 NC_009004.1 Abortive infection protein, CAAX amino terminal protease; hypothetical protein 143772 4797836 llmg_0149 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031511.1 143092 D 416870 CDS YP_001031512.1 125623029 4797869 144067..144333 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 144333 4797869 llmg_0150 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031512.1 144067 D 416870 CDS YP_001031513.1 125623030 4797916 144333..144764 1 NC_009004.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 144764 4797916 llmg_0151 Lactococcus lactis subsp. cremoris MG1363 Holliday junction resolvase-like protein YP_001031513.1 144333 D 416870 CDS YP_001031514.1 125623031 4797944 144865..145188 1 NC_009004.1 hypothetical protein 145188 4797944 llmg_0152 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031514.1 144865 D 416870 CDS YP_001031515.1 125623032 4797276 complement(145218..145769) 1 NC_009004.1 Predicted integral membrane protein; hypothetical protein 145769 4797276 llmg_0153 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031515.1 145218 R 416870 CDS YP_001031516.1 125623033 4797327 complement(145859..146644) 1 NC_009004.1 3-oxoacyl-[acyl-carrier-protein] reductase , Short- chain dehydrogenase/reductase SDR\, Fatty acid biosynthesis pathway; High confidence in function and specificity; carbonyl reductase 146644 cbr 4797327 cbr Lactococcus lactis subsp. cremoris MG1363 carbonyl reductase YP_001031516.1 145859 R 416870 CDS YP_001031517.1 125623034 4797763 complement(146664..146975) 1 NC_009004.1 hypothetical protein 146975 4797763 llmg_0155 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031517.1 146664 R 416870 CDS YP_001031518.1 125623035 4797310 complement(146985..147770) 1 NC_009004.1 3-oxoacyl-[acyl-carrier-protein] reductase, Short- chain dehydrogenase/reductase SDR, Fatty acid biosynthesis pathway; High confidence in function and specificity; oxidoreductase dltE 147770 dltE 4797310 dltE Lactococcus lactis subsp. cremoris MG1363 oxidoreductase dltE YP_001031518.1 146985 R 416870 CDS YP_001031519.1 125623036 4798364 147888..148433 1 NC_009004.1 Homeodomain-like, Bacterial regulatory proteins, tetR family; transcriptional regulator 148433 tetR 4798364 tetR Lactococcus lactis subsp. cremoris MG1363 transcriptional regulator YP_001031519.1 147888 D 416870 CDS YP_001031520.1 125623037 4797090 complement(148498..150441) 1 NC_009004.1 1,4-alpha-glucan branching enzyme , Glycogen branching enzyme, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6- glucosyl- transferase, Alpha amylase, catalytic subdomain, Isoamylase N-terminal domain, branching_enzym: 1,4-alpha- glucan branching enzyme; High confidence in function and specificity; GlgB protein 150441 glgB 4797090 glgB Lactococcus lactis subsp. cremoris MG1363 GlgB protein YP_001031520.1 148498 R 416870 CDS YP_001031521.1 125623038 4798283 complement(150562..150882) 1 NC_009004.1 hypothetical protein 150882 4798283 llmg_0159 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031521.1 150562 R 416870 CDS YP_001031522.1 125623039 4797875 151041..151679 1 NC_009004.1 FMN-dependent nitroreductase (Dihydropteridine reductase); Conserved hypothetical protein; oxygen-insensitive NAD(P)H nitroreductase 151679 4797875 llmg_0160 Lactococcus lactis subsp. cremoris MG1363 oxygen-insensitive NAD(P)H nitroreductase YP_001031522.1 151041 D 416870 CDS YP_001031523.1 125623040 4797195 151722..152270 1 NC_009004.1 Homeodomain-like, Bacterial regulatory proteins, tetR family; Conserved hypothetical protein; HTH-type transcriptional regulator 152270 4797195 llmg_0161 Lactococcus lactis subsp. cremoris MG1363 HTH-type transcriptional regulator YP_001031523.1 151722 D 416870 CDS YP_001031524.1 125623041 4798057 152726..154126 1 NC_009004.1 Bacterial adhesion, Collagen binding domain, Predicted Signal sequence; hypothetical protein 154126 4798057 llmg_0162 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031524.1 152726 D 416870 CDS YP_001031525.1 125623042 4798034 154139..154453 1 NC_009004.1 Lambda repressor-like, DNA-binding; transcriptional regulator 154453 epsR 4798034 epsR Lactococcus lactis subsp. cremoris MG1363 transcriptional regulator YP_001031525.1 154139 D 416870 CDS YP_001031526.1 125623043 4796935 complement(154740..155888) 1 NC_009004.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 155888 tgt 4796935 tgt Lactococcus lactis subsp. cremoris MG1363 queuine tRNA-ribosyltransferase YP_001031526.1 154740 R 416870 CDS YP_001031527.1 125623044 4796914 156088..156777 1 NC_009004.1 hypothetical protein 156777 4796914 llmg_0165 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031527.1 156088 D 416870 CDS YP_001031528.1 125623045 4797496 complement(158195..158632) 1 NC_009004.1 CoA binding domain; hypothetical protein 158632 4797496 llmg_0167 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031528.1 158195 R 416870 CDS YP_001031529.1 125623046 4798433 158769..159554 1 NC_009004.1 DNA/RNA non-specific endonuclease; High confidence in function and specificity; deoxyribonuclease 159554 4798433 llmg_0168 Lactococcus lactis subsp. cremoris MG1363 deoxyribonuclease YP_001031529.1 158769 D 416870 CDS YP_001031530.1 125623047 4797830 159944..160183 1 NC_009004.1 Transmembrane protein; hypothetical protein 160183 4797830 llmg_0169 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031530.1 159944 D 416870 CDS YP_001031531.1 125623048 4798444 160381..161961 1 NC_009004.1 Heme/copper-type cytochrome/quinol oxidases, subunit 1, COG: 0843; hypothetical protein 161961 4798444 llmg_0170 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031531.1 160381 D 416870 CDS YP_001031532.1 125623049 4797966 162090..163304 1 NC_009004.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase 163304 aspC 4797966 aspC Lactococcus lactis subsp. cremoris MG1363 aminotransferase YP_001031532.1 162090 D 416870 CDS YP_001031533.1 125623050 4797198 163457..164245 1 NC_009004.1 CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; transcriptional repressor CodY 164245 codY 4797198 codY Lactococcus lactis subsp. cremoris MG1363 transcriptional repressor CodY YP_001031533.1 163457 D 416870 CDS YP_001031534.1 125623051 4796783 164352..164471 1 NC_009004.1 hypothetical protein 164471 4796783 llmg_0173 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031534.1 164352 D 416870 CDS YP_001031535.1 125623052 4797604 164523..164828 1 NC_009004.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 164828 gatC 4797604 gatC Lactococcus lactis subsp. cremoris MG1363 aspartyl/glutamyl-tRNA amidotransferase subunit C YP_001031535.1 164523 D 416870 CDS YP_001031536.1 125623053 4796605 164828..166288 1 NC_009004.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 166288 gatA 4796605 gatA Lactococcus lactis subsp. cremoris MG1363 aspartyl/glutamyl-tRNA amidotransferase subunit A YP_001031536.1 164828 D 416870 CDS YP_001031537.1 125623054 4796630 166313..167746 1 NC_009004.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 167746 gatB 4796630 gatB Lactococcus lactis subsp. cremoris MG1363 aspartyl/glutamyl-tRNA amidotransferase subunit B YP_001031537.1 166313 D 416870 CDS YP_001031538.1 125623055 4797424 167870..169369 1 NC_009004.1 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases, Similar to GatA; High confidence in function and specificity; amidase 169369 4797424 llmg_0177 Lactococcus lactis subsp. cremoris MG1363 amidase YP_001031538.1 167870 D 416870 CDS YP_001031539.1 125623056 4798064 complement(169436..170776) 1 NC_009004.1 cation efflux protein (); High confidence in function and specificity; damage-inducible protein DinF 170776 dinF 4798064 dinF Lactococcus lactis subsp. cremoris MG1363 damage-inducible protein DinF YP_001031539.1 169436 R 416870 CDS YP_001031540.1 125623057 4798908 complement(170956..171153) 1 NC_009004.1 Cold-shock protein, DNA-binding; Conserved hypothetical protein; cold shock-like protein cspE 171153 cspE 4798908 cspE Lactococcus lactis subsp. cremoris MG1363 cold shock-like protein cspE YP_001031540.1 170956 R 416870 CDS YP_001031541.1 125623058 4798836 171272..171805 1 NC_009004.1 High confidence in function and specificity; 5-formyltetrahydrofolate cyclo-ligase 171805 4798836 llmg_0181 Lactococcus lactis subsp. cremoris MG1363 5-formyltetrahydrofolate cyclo-ligase YP_001031541.1 171272 D 416870 CDS YP_001031542.1 125623059 4796603 171795..172487 1 NC_009004.1 Rhomboid-like protein; High confidence in function and specificity; rhomboid-related protein 1 172487 4796603 llmg_0182 Lactococcus lactis subsp. cremoris MG1363 rhomboid-related protein 1 YP_001031542.1 171795 D 416870 CDS YP_001031543.1 125623060 4798357 172586..173017 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 173017 4798357 llmg_0183 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031543.1 172586 D 416870 CDS YP_001031544.1 125623061 4797141 173038..173418 1 NC_009004.1 Lactoylglutathione lyase , Methylglyoxalase; Aldoketomutase; Glyoxalase I, Ketone-aldehyde mutase; High confidence in function and specificity; lactoylglutathione lyase 173418 4797141 llmg_0184 Lactococcus lactis subsp. cremoris MG1363 lactoylglutathione lyase YP_001031544.1 173038 D 416870 CDS YP_001031545.1 125623062 4796675 173529..174581 1 NC_009004.1 Predicted acetyltransferase, Eis type; High confidence in function and specificity; acetyltransferase 174581 4796675 llmg_0185 Lactococcus lactis subsp. cremoris MG1363 acetyltransferase YP_001031545.1 173529 D 416870 CDS YP_001031546.1 125623063 4796663 174930..176021 1 NC_009004.1 hypothetical protein 176021 4796663 llmg_0186 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031546.1 174930 D 416870 CDS YP_001031547.1 125623064 4796591 176121..177605 1 NC_009004.1 PTS system, lichenan-specific IIC component , Phosphotransferase enzyme II, C component; High confidence in function and specificity; cellobiose-specific PTS system IIC component 177605 celB 4796591 celB Lactococcus lactis subsp. cremoris MG1363 cellobiose-specific PTS system IIC component YP_001031547.1 176121 D 416870 CDS YP_001031548.1 125623065 4796950 177731..177937 1 NC_009004.1 hypothetical protein 177937 4796950 llmg_0188 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031548.1 177731 D 416870 CDS YP_001031549.1 125623066 4796997 177934..178128 1 NC_009004.1 hypothetical protein 178128 4796997 llmg_0189 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031549.1 177934 D 416870 CDS YP_001031550.1 125623067 4798653 178257..179693 1 NC_009004.1 Beta-glucosidase , Gentiobiase; Cellobiase; Beta-D- glucoside glucohydrolase; Amygdalase, Glycoside hydrolase, family 1; High confidence in function and specificity; Beta-glucosidase A 179693 bglS 4798653 bglS Lactococcus lactis subsp. cremoris MG1363 Beta-glucosidase A YP_001031550.1 178257 D 416870 CDS YP_001031551.1 125623068 4797360 179759..180211 1 NC_009004.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 180211 dut 4797360 dut Lactococcus lactis subsp. cremoris MG1363 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_001031551.1 179759 D 416870 CDS YP_001031552.1 125623069 4796772 180304..181644 1 NC_009004.1 5'-nucleotidase precursor , Phosphoesterase-related protein; High confidence in function and specificity; 5'-nucleotidase 181644 4796772 llmg_0192 Lactococcus lactis subsp. cremoris MG1363 5'-nucleotidase YP_001031552.1 180304 D 416870 CDS YP_001031553.1 125623070 4798560 181659..182426 1 NC_009004.1 hypothetical protein 182426 4798560 llmg_0193 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031553.1 181659 D 416870 CDS YP_001031554.1 125623071 4798169 182618..183715 1 NC_009004.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 183715 4798169 llmg_0194 Lactococcus lactis subsp. cremoris MG1363 ribosomal RNA large subunit methyltransferase N YP_001031554.1 182618 D 416870 CDS YP_001031555.1 125623072 4796943 183963..184574 1 NC_009004.1 Oxygen-insensitive NAD(P)H nitroreductase; High confidence in function and specificity; NADH dehydrogenase 184574 4796943 llmg_0195 Lactococcus lactis subsp. cremoris MG1363 NADH dehydrogenase YP_001031555.1 183963 D 416870 CDS YP_001031556.1 125623073 4798174 184725..185705 1 NC_009004.1 Region start changed from 184692 to 184725 (-33 bases); prenyl transferase 185705 4798174 llmg_0196 Lactococcus lactis subsp. cremoris MG1363 prenyl transferase YP_001031556.1 184725 D 416870 CDS YP_001031557.1 125623074 4797073 185902..186807 1 NC_009004.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 186807 menA 4797073 menA Lactococcus lactis subsp. cremoris MG1363 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_001031557.1 185902 D 416870 CDS YP_001031558.1 125623075 4798355 complement(186846..187973) 1 NC_009004.1 Abortive infection protein; hypothetical protein 187973 4798355 llmg_0198 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031558.1 186846 R 416870 CDS YP_001031559.1 125623076 4797135 complement(188447..190522) 1 NC_009004.1 feoB: ferrous iron transport protein B; Conserved hypothetical protein; ferrous iron transport protein B 190522 feoB 4797135 feoB Lactococcus lactis subsp. cremoris MG1363 ferrous iron transport protein B YP_001031559.1 188447 R 416870 CDS YP_001031560.1 125623077 4797105 complement(190625..191101) 1 NC_009004.1 Transcriptional repressor, C-terminal, FeoA domain; Conserved hypothetical protein; ferrous iron transport protein A 191101 feoA 4797105 feoA Lactococcus lactis subsp. cremoris MG1363 ferrous iron transport protein A YP_001031560.1 190625 R 416870 CDS YP_001031561.1 125623078 4798539 191414..191842 1 NC_009004.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 191842 msrB 4798539 msrB Lactococcus lactis subsp. cremoris MG1363 methionine sulfoxide reductase B YP_001031561.1 191414 D 416870 CDS YP_001031562.1 125623079 4797930 complement(191970..193634) 1 NC_009004.1 Conserved hypothetical protein; kinase related to dihydroxyacetone kinase 193634 4797930 llmg_0202 Lactococcus lactis subsp. cremoris MG1363 kinase related to dihydroxyacetone kinase YP_001031562.1 191970 R 416870 CDS YP_001031563.1 125623080 4797041 complement(193634..194002) 1 NC_009004.1 hypothetical protein 194002 4797041 llmg_0203 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031563.1 193634 R 416870 CDS YP_001031564.1 125623081 4797103 complement(194276..194470) 1 NC_009004.1 required for 70S ribosome assembly; 50S ribosomal protein L28 194470 rpmB 4797103 rpmB Lactococcus lactis subsp. cremoris MG1363 50S ribosomal protein L28 YP_001031564.1 194276 R 416870 CDS YP_001031565.1 125623082 4799061 194607..195266 1 NC_009004.1 Membrane protein of unknown function; hypothetical protein 195266 4799061 llmg_0205 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031565.1 194607 D 416870 CDS YP_001031566.1 125623083 4796994 195461..196330 1 NC_009004.1 Glucose-1-phosphate thymidylyltransferase 1, dTDP- glucose synthase 1; dTDP-glucose pyrophosphorylase 1; High confidence in function and specificity; glucose-1-phosphate thymidylyltransferase 196330 rmlA 4796994 rmlA Lactococcus lactis subsp. cremoris MG1363 glucose-1-phosphate thymidylyltransferase YP_001031566.1 195461 D 416870 CDS YP_001031567.1 125623084 4797178 196330..196923 1 NC_009004.1 dTDP-4-dehydrorhamnose 3,5-epimerase, dTDP-4-keto-6- deoxyglucose 3,5-epimerase, dTDP-L-rhamnose synthetase; High confidence in function and specificity; dTDP-4-keto-6-deoxyglucose-3,5-epimerase 196923 rmlC 4797178 rmlC Lactococcus lactis subsp. cremoris MG1363 dTDP-4-keto-6-deoxyglucose-3,5-epimerase YP_001031567.1 196330 D 416870 CDS YP_001031568.1 125623085 4797193 196923..197177 1 NC_009004.1 hypothetical protein 197177 4797193 llmg_0208 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031568.1 196923 D 416870 CDS YP_001031569.1 125623086 4796876 197217..198269 1 NC_009004.1 dTDP-glucose 4,6-dehydratase 198269 rmlB 4796876 rmlB Lactococcus lactis subsp. cremoris MG1363 dTDP-glucose 4,6-dehydratase YP_001031569.1 197217 D 416870 CDS YP_001031570.1 125623087 4798414 198457..199356 1 NC_009004.1 Probable dTDP-4-dehydrorhamnose reductase, dTDP-4- keto- L-rhamnose reductase, rmlD: dTDP-4-dehydrorhamnose reductase; High confidence in function and specificity; dTDP-4-dehydrorhamnose reductase 199356 rmlD 4798414 rmlD Lactococcus lactis subsp. cremoris MG1363 dTDP-4-dehydrorhamnose reductase YP_001031570.1 198457 D 416870 CDS YP_001031571.1 125623088 4797874 199519..200727 1 NC_009004.1 polysaccharide biosynthesis protein; High confidence in function and specificity; rhamnosyltransferase RgpA 200727 rgpA 4797874 rgpA Lactococcus lactis subsp. cremoris MG1363 rhamnosyltransferase RgpA YP_001031571.1 199519 D 416870 CDS YP_001031572.1 125623089 4797088 200717..201658 1 NC_009004.1 Glycosyl transferase, family 2, polysaccharide synthesis protein; High confidence in function and specificity; rhamnosyltransferase RgpB 201658 rgpB 4797088 rgpB Lactococcus lactis subsp. cremoris MG1363 rhamnosyltransferase RgpB YP_001031572.1 200717 D 416870 CDS YP_001031573.1 125623090 4796700 201655..202464 1 NC_009004.1 ABC-2 type transporter; Conserved hypothetical protein; capsule polysaccharide export inner-membrane protein RgpC 202464 rgpC 4796700 rgpC Lactococcus lactis subsp. cremoris MG1363 capsule polysaccharide export inner-membrane protein RgpC YP_001031573.1 201655 D 416870 CDS YP_001031574.1 125623091 4798493 202479..203672 1 NC_009004.1 High confidence in function and specificity; polysaccharide ABC transporter ATP-binding protein 203672 rgpD 4798493 rgpD Lactococcus lactis subsp. cremoris MG1363 polysaccharide ABC transporter ATP-binding protein YP_001031574.1 202479 D 416870 CDS YP_001031575.1 125623092 4797077 203650..205041 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 205041 4797077 llmg_0215 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031575.1 203650 D 416870 CDS YP_001031576.1 125623093 4796954 205049..206005 1 NC_009004.1 Glycosyl transferase, family 2; High confidence in function and specificity; glycosyltransferase RgpE 206005 rgpE 4796954 rgpE Lactococcus lactis subsp. cremoris MG1363 glycosyltransferase RgpE YP_001031576.1 205049 D 416870 CDS YP_001031577.1 125623094 4796998 205995..207761 1 NC_009004.1 Rhamnan synthesis protein F, polysaccharide biosynthesis protein; High confidence in function and specificity; alpha-L-Rha alpha-1,3-L-rhamnosyltransferase 207761 rgpF 4796998 rgpF Lactococcus lactis subsp. cremoris MG1363 alpha-L-Rha alpha-1,3-L-rhamnosyltransferase YP_001031577.1 205995 D 416870 CDS YP_001031578.1 125623095 4796898 207843..208580 1 NC_009004.1 Glycosyl transferase, family 2; High confidence in function and specificity; glycosyl transferase family protein 208580 4796898 llmg_0218 Lactococcus lactis subsp. cremoris MG1363 glycosyl transferase family protein YP_001031578.1 207843 D 416870 CDS YP_001031579.1 125623096 4796881 208580..208933 1 NC_009004.1 hypothetical protein 208933 4796881 llmg_0219 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031579.1 208580 D 416870 CDS YP_001031580.1 125623097 4796874 208969..209763 1 NC_009004.1 Glycosyl transferase, family 2; Conserved hypothetical protein; glycosyl transferase family protein 209763 4796874 llmg_0220 Lactococcus lactis subsp. cremoris MG1363 glycosyl transferase family protein YP_001031580.1 208969 D 416870 CDS YP_001031581.1 125623098 4798173 209769..210761 1 NC_009004.1 Glycosyl transferase, family 2; Conserved hypothetical protein; glycosyl transferase family protein 210761 4798173 llmg_0221 Lactococcus lactis subsp. cremoris MG1363 glycosyl transferase family protein YP_001031581.1 209769 D 416870 CDS YP_001031582.1 125623099 4796766 210754..211752 1 NC_009004.1 hypothetical protein 211752 wefC 4796766 wefC Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031582.1 210754 D 416870 CDS YP_001031583.1 125623100 4797953 211819..212853 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 212853 4797953 llmg_0223 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031583.1 211819 D 416870 CDS YP_001031584.1 125623101 4798554 212853..213983 1 NC_009004.1 High confidence in function and specificity; Glf1 protein 213983 glf1 4798554 glf1 Lactococcus lactis subsp. cremoris MG1363 Glf1 protein YP_001031584.1 212853 D 416870 CDS YP_001031585.1 125623102 4798485 213980..215398 1 NC_009004.1 Polysaccharide biosynthesis protein; Family membership; O-antigen transporter 215398 rfbX 4798485 rfbX Lactococcus lactis subsp. cremoris MG1363 O-antigen transporter YP_001031585.1 213980 D 416870 CDS YP_001031586.1 125623103 4796944 215427..217226 1 NC_009004.1 surface protein 217226 4796944 llmg_0226 Lactococcus lactis subsp. cremoris MG1363 surface protein YP_001031586.1 215427 D 416870 CDS YP_001031587.1 125623104 4796681 217228..218283 1 NC_009004.1 hypothetical protein 218283 4796681 llmg_0227 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031587.1 217228 D 416870 CDS YP_001031588.1 125623105 4796985 218280..218654 1 NC_009004.1 hypothetical protein 218654 4796985 llmg_0228 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031588.1 218280 D 416870 CDS YP_001031589.1 125623106 4797064 complement(218798..220096) 1 NC_009004.1 Glycoside hydrolase, family 25; Family membership; hypothetical protein 220096 4797064 llmg_0229 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031589.1 218798 R 416870 CDS YP_001031590.1 125623107 4797333 220476..221957 1 NC_009004.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 221957 guaB 4797333 guaB Lactococcus lactis subsp. cremoris MG1363 inosine 5'-monophosphate dehydrogenase YP_001031590.1 220476 D 416870 CDS YP_001031591.1 125623108 4796854 222183..223328 1 NC_009004.1 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis; GTP-binding protein YqeH 223328 4796854 llmg_0231 Lactococcus lactis subsp. cremoris MG1363 GTP-binding protein YqeH YP_001031591.1 222183 D 416870 CDS YP_001031592.1 125623109 4796742 223423..223926 1 NC_009004.1 Probable (di)nucleoside polyphosphate hydrolase., MutT/Nudix family protein; Family membership; hypothetical protein 223926 4796742 llmg_0232 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031592.1 223423 D 416870 CDS YP_001031593.1 125623110 4798492 224009..225253 1 NC_009004.1 GTP-binding protein, HSR1-related; High confidence in function and specificity; GTP-binding protein HflX 225253 hflX 4798492 hflX Lactococcus lactis subsp. cremoris MG1363 GTP-binding protein HflX YP_001031593.1 224009 D 416870 CDS YP_001031594.1 125623111 4797589 complement(225382..225708) 1 NC_009004.1 hypothetical protein 225708 4797589 llmg_0234 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031594.1 225382 R 416870 CDS YP_001031595.1 125623112 4798196 225877..226191 1 NC_009004.1 Protein of unknown function UPF0044, contains CRS1 / YhbY domain; hypothetical protein 226191 4798196 llmg_0235 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031595.1 225877 D 416870 CDS YP_001031596.1 125623113 4797021 226266..226865 1 NC_009004.1 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase; High confidence in function and specificity; nicotinate-nucleotide adenylyltransferase 226865 nadD1 4797021 nadD1 Lactococcus lactis subsp. cremoris MG1363 nicotinate-nucleotide adenylyltransferase YP_001031596.1 226266 D 416870 CDS YP_001031597.1 125623114 4798115 226858..227448 1 NC_009004.1 PF01966.9: Metal-dependent phosphohydrolase, HD subdomain, TIGR00488: conserved hypothetical protein TIGR00488; hydrolase 227448 4798115 llmg_0237 Lactococcus lactis subsp. cremoris MG1363 hydrolase YP_001031597.1 226858 D 416870 CDS YP_001031598.1 125623115 4797067 227495..227926 1 NC_009004.1 GCN5-related N-acetyltransferase; Family membership; hypothetical protein 227926 4797067 llmg_0238 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031598.1 227495 D 416870 CDS YP_001031599.1 125623116 4798209 228093..228452 1 NC_009004.1 Domain of unknown function DUF143, TIGR00090: iojap- related protein; hypothetical protein 228452 4798209 llmg_0239 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031599.1 228093 D 416870 CDS YP_001031600.1 125623117 4797110 228552..229286 1 NC_009004.1 contains SAM (and some other nucleotide) binding motif; hypothetical protein 229286 4797110 llmg_0240 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031600.1 228552 D 416870 CDS YP_001031601.1 125623118 4796928 229336..230475 1 NC_009004.1 Protein of unknown function DUF795; Family membership; hypothetical protein 230475 4796928 llmg_0241 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031601.1 229336 D 416870 CDS YP_001031602.1 125623119 4796983 230628..231344 1 NC_009004.1 PF01709.9: Protein of unknown function DUF28; hypothetical protein 231344 4796983 llmg_0242 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031602.1 230628 D 416870 CDS YP_001031603.1 125623120 4797500 232047..232706 1 NC_009004.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 232706 ung 4797500 ung Lactococcus lactis subsp. cremoris MG1363 uracil-DNA glycosylase YP_001031603.1 232047 D 416870 CDS YP_001031604.1 125623121 4797173 complement(232743..233654) 1 NC_009004.1 Zinc-containing alcohol dehydrogenase superfamily; Family membership; zinc-binding dehydrogenase 233654 4797173 llmg_0245 Lactococcus lactis subsp. cremoris MG1363 zinc-binding dehydrogenase YP_001031604.1 232743 R 416870 CDS YP_001031605.1 125623122 4798496 complement(233677..234555) 1 NC_009004.1 hypothetical protein 234555 4798496 llmg_0246 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031605.1 233677 R 416870 CDS YP_001031606.1 125623123 4797582 complement(234577..235416) 1 NC_009004.1 Function unclear; UDP-glucose 4-epimerase 235416 4797582 llmg_0247 Lactococcus lactis subsp. cremoris MG1363 UDP-glucose 4-epimerase YP_001031606.1 234577 R 416870 CDS YP_001031607.1 125623124 4797557 235620..236165 1 NC_009004.1 Function unclear; TetR family transcriptional regulator 236165 4797557 llmg_0248 Lactococcus lactis subsp. cremoris MG1363 TetR family transcriptional regulator YP_001031607.1 235620 D 416870 CDS YP_001031608.1 125623125 4798039 complement(236277..237737) 1 NC_009004.1 Major facilitator superfamily; Family membership; transporter 237737 4798039 llmg_0249 Lactococcus lactis subsp. cremoris MG1363 transporter YP_001031608.1 236277 R 416870 CDS YP_001031609.1 125623126 4798312 237923..238294 1 NC_009004.1 DNA binding HTH containing; Family membership; MerR family transcriptional regulator 238294 rmeC 4798312 rmeC Lactococcus lactis subsp. cremoris MG1363 MerR family transcriptional regulator YP_001031609.1 237923 D 416870 CDS YP_001031610.1 125623127 4797824 238375..238551 1 NC_009004.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 238551 rpsU 4797824 rpsU Lactococcus lactis subsp. cremoris MG1363 30S ribosomal protein S21 YP_001031610.1 238375 D 416870 CDS YP_001031611.1 125623128 4797369 238659..239471 1 NC_009004.1 Cof protein, HAD-SF-IIB: predicted HAD-superfamily hydrolase, subfamily IIB; Family membership; hypothetical protein 239471 4797369 llmg_0252 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031611.1 238659 D 416870 CDS YP_001031612.1 125623129 4797899 239673..240869 1 NC_009004.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 240869 pgk 4797899 pgk Lactococcus lactis subsp. cremoris MG1363 phosphoglycerate kinase YP_001031612.1 239673 D 416870 CDS YP_001031613.1 125623130 4798385 240927..241601 1 NC_009004.1 (S)-2-haloacid dehalogenase (Halocarboxylic acid halidohydrolase), Haloacid dehalogenase, type II; High confidence in function and specificity; cryptic haloacid dehalogenase 1 241601 hadL 4798385 hadL Lactococcus lactis subsp. cremoris MG1363 cryptic haloacid dehalogenase 1 YP_001031613.1 240927 D 416870 CDS YP_001031614.1 125623131 4797546 241721..242707 1 NC_009004.1 similar to DhaK; in Lactococcus lactis this protein froms a stable complex with DhaS and activates transcription of the dha operon in the presence of dihydroxyacetone; DhaKLM operon coactivator DhaQ 242707 dhaK 4797546 dhaK Lactococcus lactis subsp. cremoris MG1363 DhaKLM operon coactivator DhaQ YP_001031614.1 241721 D 416870 CDS YP_001031615.1 125623132 4798904 244314..244892 1 NC_009004.1 Dihydroxyacetone kinase (Glycerone kinase) (DHA kinase), DAK2 domain; High confidence in function and specificity; dihydroxyacetone kinase DhaM 244892 dhaM 4798904 dhaM Lactococcus lactis subsp. cremoris MG1363 dihydroxyacetone kinase DhaM YP_001031615.1 244314 D 416870 CDS YP_001031616.1 125623133 4798906 244889..245260 1 NC_009004.1 PF03610.4: PTS system fructose subfamily IIA component; hypothetical protein 245260 4798906 llmg_0258 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031616.1 244889 D 416870 CDS YP_001031617.1 125623134 4798470 complement(245939..247321) 1 NC_009004.1 Peptidase U34; High confidence in function and specificity; PepDA protein 247321 pepDA 4798470 pepDA Lactococcus lactis subsp. cremoris MG1363 PepDA protein YP_001031617.1 245939 R 416870 CDS YP_001031618.1 125623135 4797511 248309..249451 1 NC_009004.1 Specificity unclear; ABC transporter permease 249451 4797511 llmg_0262 Lactococcus lactis subsp. cremoris MG1363 ABC transporter permease YP_001031618.1 248309 D 416870 CDS YP_001031619.1 125623136 4797376 249574..250743 1 NC_009004.1 PS50193: contains SAM (and some other nucleotide) binding motif; Family membership; methyltransferase 250743 4797376 llmg_0263 Lactococcus lactis subsp. cremoris MG1363 methyltransferase YP_001031619.1 249574 D 416870 CDS YP_001031620.1 125623137 4799147 250908..252830 1 NC_009004.1 High confidence in function and specificity; fructose-bisphosphatase 252830 fbp 4799147 fbp Lactococcus lactis subsp. cremoris MG1363 fructose-bisphosphatase YP_001031620.1 250908 D 416870 CDS YP_001031621.1 125623138 4796574 complement(253062..254336) 1 NC_009004.1 TIGR00275: conserved hypothetical protein TIGR00275; flavoprotein 254336 4796574 llmg_0265 Lactococcus lactis subsp. cremoris MG1363 flavoprotein YP_001031621.1 253062 R 416870 CDS YP_001031622.1 125623139 4799141 254374..255204 1 NC_009004.1 Protein of unknown function UPF0031; Family membership; sugar kinase 255204 4799141 llmg_0266 Lactococcus lactis subsp. cremoris MG1363 sugar kinase YP_001031622.1 254374 D 416870 CDS YP_001031623.1 125623140 4798937 255275..255688 1 NC_009004.1 hypothetical protein 255688 4798937 llmg_0267 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031623.1 255275 D 416870 CDS YP_001031624.1 125623141 4798930 255940..257721 1 NC_009004.1 Specificity unclear; ABC transporter ATP-binding protein 257721 4798930 llmg_0268 Lactococcus lactis subsp. cremoris MG1363 ABC transporter ATP-binding protein YP_001031624.1 255940 D 416870 CDS YP_001031625.1 125623142 4798618 257718..259616 1 NC_009004.1 Specificity unclear; ABC transporter ATP-binding and permease 259616 4798618 llmg_0269 Lactococcus lactis subsp. cremoris MG1363 ABC transporter ATP-binding and permease YP_001031625.1 257718 D 416870 CDS YP_001031626.1 125623143 4798504 259707..260372 1 NC_009004.1 hypothetical protein 260372 4798504 llmg_0270 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031626.1 259707 D 416870 CDS YP_001031627.1 125623144 4798503 complement(260420..261439) 1 NC_009004.1 Family membership; Gfo/Idh/MocA family oxidoreductase 261439 4798503 llmg_0271 Lactococcus lactis subsp. cremoris MG1363 Gfo/Idh/MocA family oxidoreductase YP_001031627.1 260420 R 416870 CDS YP_001031628.1 125623145 4798279 complement(261423..261590) 1 NC_009004.1 hypothetical protein 261590 4798279 llmg_0272 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031628.1 261423 R 416870 CDS YP_001031629.1 125623146 4798265 complement(261789..262265) 1 NC_009004.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 262265 luxS 4798265 luxS Lactococcus lactis subsp. cremoris MG1363 S-ribosylhomocysteinase YP_001031629.1 261789 R 416870 CDS YP_001031630.1 125623147 4797657 262484..262717 1 NC_009004.1 SSF55136: Bacterial regulatory factor, effector; Family membership; hypothetical protein 262717 4797657 llmg_0274 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031630.1 262484 D 416870 CDS YP_001031631.1 125623148 4797242 262808..262948 1 NC_009004.1 hypothetical protein 262948 4797242 llmg_0275 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031631.1 262808 D 416870 CDS YP_001031632.1 125623149 4797232 263015..263860 1 NC_009004.1 Family membership; aldo/keto reductase 263860 4797232 llmg_0276 Lactococcus lactis subsp. cremoris MG1363 aldo/keto reductase YP_001031632.1 263015 D 416870 CDS YP_001031633.1 125623150 4797223 264100..264612 1 NC_009004.1 Family membership; amidase 264612 4797223 llmg_0277 Lactococcus lactis subsp. cremoris MG1363 amidase YP_001031633.1 264100 D 416870 CDS YP_001031634.1 125623151 4797210 264727..265275 1 NC_009004.1 hypothetical protein 265275 4797210 llmg_0278 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031634.1 264727 D 416870 CDS YP_001031635.1 125623152 4797207 265272..265556 1 NC_009004.1 hypothetical protein 265556 4797207 llmg_0279 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031635.1 265272 D 416870 CDS YP_001031636.1 125623153 4797197 complement(265605..266918) 1 NC_009004.1 High confidence in function and specificity; N-acetylglucosaminidase 266918 acmA 4797197 acmA Lactococcus lactis subsp. cremoris MG1363 N-acetylglucosaminidase YP_001031636.1 265605 R 416870 CDS YP_001031637.1 125623154 4798795 267262..269505 1 NC_009004.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 269505 4798795 llmg_0281 Lactococcus lactis subsp. cremoris MG1363 anaerobic ribonucleoside triphosphate reductase YP_001031637.1 267262 D 416870 CDS YP_001031638.1 125623155 4798410 269508..270107 1 NC_009004.1 High confidence in function and specificity; anaerobic ribonucleoside-triphosphate reductase activating protein 270107 nrdG 4798410 nrdG Lactococcus lactis subsp. cremoris MG1363 anaerobic ribonucleoside-triphosphate reductase activating protein YP_001031638.1 269508 D 416870 CDS YP_001031639.1 125623156 4796572 complement(270179..270688) 1 NC_009004.1 hypothetical protein 270688 4796572 llmg_0283 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031639.1 270179 R 416870 CDS YP_001031640.1 125623157 4797547 270892..272277 1 NC_009004.1 hypothetical protein 272277 4797547 llmg_0284 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031640.1 270892 D 416870 CDS YP_001031641.1 125623158 4796625 complement(273847..275316) 1 NC_009004.1 contains WD40 repeat domain; hypothetical protein 275316 4796625 llmg_0286 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031641.1 273847 R 416870 CDS YP_001031642.1 125623159 4798204 276119..276952 1 NC_009004.1 with CbiNQ forms the ABC transporter for cobalt import; Lactococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit 276952 cbiO 4798204 cbiO Lactococcus lactis subsp. cremoris MG1363 cobalt transporter ATP-binding subunit YP_001031642.1 276119 D 416870 CDS YP_001031643.1 125623160 4797678 277084..277950 1 NC_009004.1 with CbiNQ forms the ABC transporter for cobalt import; Lactococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit 277950 cbiO 4797678 cbiO Lactococcus lactis subsp. cremoris MG1363 cobalt transporter ATP-binding subunit YP_001031643.1 277084 D 416870 CDS YP_001031644.1 125623161 4797660 277950..278750 1 NC_009004.1 High confidence in function and specificity; cobalt ABC transporter permease 278750 cbiQ2 4797660 cbiQ2 Lactococcus lactis subsp. cremoris MG1363 cobalt ABC transporter permease YP_001031644.1 277950 D 416870 CDS YP_001031645.1 125623162 4796814 278772..279383 1 NC_009004.1 hypothetical protein 279383 4796814 llmg_0290 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031645.1 278772 D 416870 CDS YP_001031646.1 125623163 4798118 279596..280366 1 NC_009004.1 High confidence in function and specificity; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 280366 dapD 4798118 dapD Lactococcus lactis subsp. cremoris MG1363 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase YP_001031646.1 279596 D 416870 CDS YP_001031647.1 125623164 4798877 280504..281634 1 NC_009004.1 High confidence in function and specificity; hippurate hydrolase 281634 hipO1 4798877 hipO1 Lactococcus lactis subsp. cremoris MG1363 hippurate hydrolase YP_001031647.1 280504 D 416870 CDS YP_001031648.1 125623165 4797603 281791..282912 1 NC_009004.1 High confidence in function and specificity; endo-1,4-beta-xylanase D 282912 xynD 4797603 xynD Lactococcus lactis subsp. cremoris MG1363 endo-1,4-beta-xylanase D YP_001031648.1 281791 D 416870 CDS YP_001031649.1 125623166 4796995 283549..283656 1 NC_009004.1 hypothetical protein 283656 4796995 llmg_0294 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031649.1 283549 D 416870 CDS YP_001031650.1 125623167 4798629 283783..285207 1 NC_009004.1 hypothetical protein 285207 4798629 llmg_0295 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031650.1 283783 D 416870 CDS YP_001031651.1 125623168 4798643 285418..286029 1 NC_009004.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 286029 rpsD 4798643 rpsD Lactococcus lactis subsp. cremoris MG1363 30S ribosomal protein S4 YP_001031651.1 285418 D 416870 CDS YP_001031652.1 125623169 4799021 286157..288298 1 NC_009004.1 contains S1 RNA binding domain; High confidence in function and specificity; transcription accessory protein TEX 288298 tex 4799021 tex Lactococcus lactis subsp. cremoris MG1363 transcription accessory protein TEX YP_001031652.1 286157 D 416870 CDS YP_001031653.1 125623170 4796932 288431..288874 1 NC_009004.1 metallopeptidase (SprT family); Family membership; hypothetical protein 288874 4796932 llmg_0298 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031653.1 288431 D 416870 CDS YP_001031654.1 125623171 4798649 289175..290209 1 NC_009004.1 catalyzes the formation of inosine from adenosine; adenosine deaminase 290209 add 4798649 add Lactococcus lactis subsp. cremoris MG1363 adenosine deaminase YP_001031654.1 289175 D 416870 CDS YP_001031655.1 125623172 4796670 complement(290224..290661) 1 NC_009004.1 hypothetical protein 290661 4796670 llmg_0300 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031655.1 290224 R 416870 CDS YP_001031656.1 125623173 4798626 complement(290697..291065) 1 NC_009004.1 Family membership; MerR family transcriptional regulator 291065 4798626 llmg_0301 Lactococcus lactis subsp. cremoris MG1363 MerR family transcriptional regulator YP_001031656.1 290697 R 416870 CDS YP_001031657.1 125623174 4797784 complement(291217..292902) 1 NC_009004.1 Conserved hypothetical protein MG423; Family membership; Zn-dependent hydrolase 292902 4797784 llmg_0302 Lactococcus lactis subsp. cremoris MG1363 Zn-dependent hydrolase YP_001031657.1 291217 R 416870 CDS YP_001031658.1 125623175 4798348 complement(293096..293326) 1 NC_009004.1 Protein of unknown function DUF1447; hypothetical protein 293326 4798348 llmg_0304 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031658.1 293096 R 416870 CDS YP_001031659.1 125623176 4797209 293431..293568 1 NC_009004.1 hypothetical protein 293568 4797209 llmg_0305 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031659.1 293431 D 416870 CDS YP_001031660.1 125623177 4797241 293664..294389 1 NC_009004.1 Family membership; O-sialoglycoprotein endopeptidase 294389 4797241 llmg_0306 Lactococcus lactis subsp. cremoris MG1363 O-sialoglycoprotein endopeptidase YP_001031660.1 293664 D 416870 CDS YP_001031661.1 125623178 4798280 294343..294912 1 NC_009004.1 Region start changed from 294277 to 294343 (-66 bases); ribosomal-protein-alanine N-acetyltransferase 294912 4798280 llmg_0307 Lactococcus lactis subsp. cremoris MG1363 ribosomal-protein-alanine N-acetyltransferase YP_001031661.1 294343 D 416870 CDS YP_001031662.1 125623179 4797231 294909..295379 1 NC_009004.1 High confidence in function and specificity; ribosomal-protein-alanine acetyltransferase 295379 rimI2 4797231 rimI2 Lactococcus lactis subsp. cremoris MG1363 ribosomal-protein-alanine acetyltransferase YP_001031662.1 294909 D 416870 CDS YP_001031663.1 125623180 4798498 295382..296407 1 NC_009004.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 296407 gcp 4798498 gcp Lactococcus lactis subsp. cremoris MG1363 DNA-binding/iron metalloprotein/AP endonuclease YP_001031663.1 295382 D 416870 CDS YP_001031664.1 125623181 4796606 296422..296622 1 NC_009004.1 hypothetical protein 296622 4796606 llmg_0310 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031664.1 296422 D 416870 CDS YP_001031665.1 125623182 4796831 complement(296970..297761) 1 NC_009004.1 hypothetical protein 297761 4796831 llmg_0311 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031665.1 296970 R 416870 CDS YP_001031666.1 125623183 4797365 298060..299109 1 NC_009004.1 phosphonate ABC transporter phosphonate-binding protein phnD 299109 phnD 4797365 phnD Lactococcus lactis subsp. cremoris MG1363 phosphonate ABC transporter phosphonate-binding protein phnD YP_001031666.1 298060 D 416870 CDS YP_001031667.1 125623184 4799105 299225..299965 1 NC_009004.1 High confidence in function and specificity; phosphonates import ATP-binding protein phnC 299965 phnC 4799105 phnC Lactococcus lactis subsp. cremoris MG1363 phosphonates import ATP-binding protein phnC YP_001031667.1 299225 D 416870 CDS YP_001031668.1 125623185 4798213 299966..300778 1 NC_009004.1 High confidence in function and specificity; phosphonate transport system permease phnB 300778 phnB 4798213 phnB Lactococcus lactis subsp. cremoris MG1363 phosphonate transport system permease phnB YP_001031668.1 299966 D 416870 CDS YP_001031669.1 125623186 4796676 300798..301607 1 NC_009004.1 Region start changed from 300786 to 300798 (-12 bases); phosphonate ABC transporter permease 301607 4796676 llmg_0315 Lactococcus lactis subsp. cremoris MG1363 phosphonate ABC transporter permease YP_001031669.1 300798 D 416870 CDS YP_001031670.1 125623187 4798449 301611..303173 1 NC_009004.1 High confidence in function and specificity; 2,3-cyclic-nucleotide 2'phosphodiesterase 303173 cpdC 4798449 cpdC Lactococcus lactis subsp. cremoris MG1363 2,3-cyclic-nucleotide 2'phosphodiesterase YP_001031670.1 301611 D 416870 CDS YP_001031671.1 125623188 4798812 303317..303436 1 NC_009004.1 hypothetical protein 303436 4798812 llmg_0317 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031671.1 303317 D 416870 CDS YP_001031672.1 125623189 4797598 303499..303981 1 NC_009004.1 High confidence in function and specificity; thiol peroxidase 303981 tpx 4797598 tpx Lactococcus lactis subsp. cremoris MG1363 thiol peroxidase YP_001031672.1 303499 D 416870 CDS YP_001031673.1 125623190 4797345 304150..306690 1 NC_009004.1 High confidence in function and specificity; PepN protein 306690 pepN 4797345 pepN Lactococcus lactis subsp. cremoris MG1363 PepN protein YP_001031673.1 304150 D 416870 CDS YP_001031674.1 125623191 4798141 complement(306738..307928) 1 NC_009004.1 tetracycline resistance protein; High confidence in function and specificity; multidrug-efflux transporter protein 307928 napC 4798141 napC Lactococcus lactis subsp. cremoris MG1363 multidrug-efflux transporter protein YP_001031674.1 306738 R 416870 CDS YP_001031675.1 125623192 4798013 complement(308410..308883) 1 NC_009004.1 High confidence in function and specificity; MarR family transcriptional regulator 308883 napB 4798013 napB Lactococcus lactis subsp. cremoris MG1363 MarR family transcriptional regulator YP_001031675.1 308410 R 416870 CDS YP_001031676.1 125623193 4797817 complement(308880..310163) 1 NC_009004.1 CDF: cation diffusion facilitator family transporter; Family membership; cation transporter 310163 4797817 llmg_0322 Lactococcus lactis subsp. cremoris MG1363 cation transporter YP_001031676.1 308880 R 416870 CDS YP_001031677.1 125623194 4797596 310439..310789 1 NC_009004.1 PF03551.4: Transcriptional regulator PadR-like family; Function unclear; PadR-like family transcriptional regulator 310789 4797596 llmg_0323 Lactococcus lactis subsp. cremoris MG1363 PadR-like family transcriptional regulator YP_001031677.1 310439 D 416870 CDS YP_001031678.1 125623195 4798592 311092..312831 1 NC_009004.1 ABC transporter ATP binding and permease; High confidence in function and specificity; multidrug resistance protein C 312831 lmrC 4798592 lmrC Lactococcus lactis subsp. cremoris MG1363 multidrug resistance protein C YP_001031678.1 311092 D 416870 CDS YP_001031679.1 125623196 4796616 312835..314829 1 NC_009004.1 ABC transporter ATP-binding/membrane spanning protein; High confidence in function and specificity; multidrug resistance protein D 314829 lmrD 4796616 lmrD Lactococcus lactis subsp. cremoris MG1363 multidrug resistance protein D YP_001031679.1 312835 D 416870 CDS YP_001031680.1 125623197 4797703 315003..316265 1 NC_009004.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 316265 murA1 4797703 murA1 Lactococcus lactis subsp. cremoris MG1363 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_001031680.1 315003 D 416870 CDS YP_001031681.1 125623198 4798325 316311..316529 1 NC_009004.1 hypothetical protein 316529 4798325 llmg_0327 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031681.1 316311 D 416870 CDS YP_001031682.1 125623199 4798769 316793..317443 1 NC_009004.1 hypothetical protein 317443 4798769 llmg_0328 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031682.1 316793 D 416870 CDS YP_001031683.1 125623200 4797600 317445..319160 1 NC_009004.1 Family membership; ABC transporter ATP binding and permease 319160 4797600 llmg_0329 Lactococcus lactis subsp. cremoris MG1363 ABC transporter ATP binding and permease YP_001031683.1 317445 D 416870 CDS YP_001031684.1 125623201 4797548 319313..320194 1 NC_009004.1 Major facilitator superfamily; Family membership; permease 320194 4797548 llmg_0330 Lactococcus lactis subsp. cremoris MG1363 permease YP_001031684.1 319313 D 416870 CDS YP_001031685.1 125623202 4798335 complement(320425..320781) 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 320781 4798335 llmg_0331 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031685.1 320425 R 416870 CDS YP_001031686.1 125623203 4796802 complement(320805..321353) 1 NC_009004.1 BioY family; Specificity unclear; hypothetical protein 321353 4796802 llmg_0332 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031686.1 320805 R 416870 CDS YP_001031687.1 125623204 4797580 complement(321464..321940) 1 NC_009004.1 YbaK/prolyl-tRNA synthetase associated region, PF04073.3: YbaK_EbsC: ybaK/ebsC protein; hypothetical protein 321940 4797580 llmg_0333 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031687.1 321464 R 416870 CDS YP_001031688.1 125623205 4796873 complement(322003..322551) 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 322551 4796873 llmg_0334 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031688.1 322003 R 416870 CDS YP_001031689.1 125623206 4796804 323286..324146 1 NC_009004.1 High confidence in function and specificity; D-methionine-binding lipoprotein plpA precursor 324146 plpA 4796804 plpA Lactococcus lactis subsp. cremoris MG1363 D-methionine-binding lipoprotein plpA precursor YP_001031689.1 323286 D 416870 CDS YP_001031690.1 125623207 4796731 324291..325151 1 NC_009004.1 High confidence in function and specificity; D-methionine-binding lipoprotein plpB precursor 325151 plpB 4796731 plpB Lactococcus lactis subsp. cremoris MG1363 D-methionine-binding lipoprotein plpB precursor YP_001031690.1 324291 D 416870 CDS YP_001031691.1 125623208 4796583 325297..326160 1 NC_009004.1 High confidence in function and specificity; D-methionine-binding lipoprotein plpC precursor 326160 plpC 4796583 plpC Lactococcus lactis subsp. cremoris MG1363 D-methionine-binding lipoprotein plpC precursor YP_001031691.1 325297 D 416870 CDS YP_001031692.1 125623209 4798623 326229..326999 1 NC_009004.1 High confidence in function and specificity; acetoin(diacetyl)reductase 326999 dar 4798623 dar Lactococcus lactis subsp. cremoris MG1363 acetoin(diacetyl)reductase YP_001031692.1 326229 D 416870 CDS YP_001031693.1 125623210 4798880 327015..327875 1 NC_009004.1 High confidence in function and specificity; D-methionine-binding lipoprotein plpD precursor 327875 plpD 4798880 plpD Lactococcus lactis subsp. cremoris MG1363 D-methionine-binding lipoprotein plpD precursor YP_001031693.1 327015 D 416870 CDS YP_001031694.1 125623211 4796615 327999..329105 1 NC_009004.1 High confidence in function and specificity; amino acid ABC transporter ATP binding protein 329105 4796615 llmg_0341 Lactococcus lactis subsp. cremoris MG1363 amino acid ABC transporter ATP binding protein YP_001031694.1 327999 D 416870 CDS YP_001031695.1 125623212 4797186 329105..329800 1 NC_009004.1 Specificity unclear; amino acid ABC transporter permease 329800 4797186 llmg_0342 Lactococcus lactis subsp. cremoris MG1363 amino acid ABC transporter permease YP_001031695.1 329105 D 416870 CDS YP_001031696.1 125623213 4799031 329843..330391 1 NC_009004.1 Protein of unknown function DUF1393; Conserved hypothetical protein; hypothetical protein 330391 4799031 llmg_0343 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031696.1 329843 D 416870 CDS YP_001031697.1 125623214 4798558 330510..332207 1 NC_009004.1 High confidence in function and specificity; cobalt ABC transporter ATP-binding protein 332207 cbiO 4798558 cbiO Lactococcus lactis subsp. cremoris MG1363 cobalt ABC transporter ATP-binding protein YP_001031697.1 330510 D 416870 CDS YP_001031698.1 125623215 4797658 332200..333021 1 NC_009004.1 High confidence in function and specificity; cobalt ABC transporter permease 333021 cbiQ 4797658 cbiQ Lactococcus lactis subsp. cremoris MG1363 cobalt ABC transporter permease YP_001031698.1 332200 D 416870 CDS YP_001031699.1 125623216 4799135 333550..334329 1 NC_009004.1 High confidence in function and specificity; ferrichrome ABC transporter fhuC 334329 fhuC 4799135 fhuC Lactococcus lactis subsp. cremoris MG1363 ferrichrome ABC transporter fhuC YP_001031699.1 333550 D 416870 CDS YP_001031700.1 125623217 4797020 334322..335272 1 NC_009004.1 High confidence in function and specificity; ferrichrome ABC transporter permease 335272 fhuB 4797020 fhuB Lactococcus lactis subsp. cremoris MG1363 ferrichrome ABC transporter permease YP_001031700.1 334322 D 416870 CDS YP_001031701.1 125623218 4797044 335273..336211 1 NC_009004.1 High confidence in function and specificity; ferrichrome ABC transporter permease 336211 fhuG 4797044 fhuG Lactococcus lactis subsp. cremoris MG1363 ferrichrome ABC transporter permease YP_001031701.1 335273 D 416870 CDS YP_001031702.1 125623219 4797014 336295..337236 1 NC_009004.1 High confidence in function and specificity; ferrichrome ABC transporter substrate-binding protein 337236 fhuD 4797014 fhuD Lactococcus lactis subsp. cremoris MG1363 ferrichrome ABC transporter substrate-binding protein YP_001031702.1 336295 D 416870 CDS YP_001031703.1 125623220 4797038 337298..338203 1 NC_009004.1 Also known as transcriptional activator of metCcysK operon cmbR; High confidence in function and specificity; HTH-type transcriptional regulator fhuR 338203 fhuR 4797038 fhuR Lactococcus lactis subsp. cremoris MG1363 HTH-type transcriptional regulator fhuR YP_001031703.1 337298 D 416870 CDS YP_001031704.1 125623221 4796972 complement(338265..339440) 1 NC_009004.1 Major facilitator superfamily; Family membership; arabinose efflux permease 339440 araJ 4796972 araJ Lactococcus lactis subsp. cremoris MG1363 arabinose efflux permease YP_001031704.1 338265 R 416870 CDS YP_001031705.1 125623222 4798241 complement(339453..340271) 1 NC_009004.1 Aldo/keto reductase; Family membership; aldo/keto reductase 340271 4798241 llmg_0352 Lactococcus lactis subsp. cremoris MG1363 aldo/keto reductase YP_001031705.1 339453 R 416870 CDS YP_001031706.1 125623223 4796636 340413..340760 1 NC_009004.1 Protein of unknown function DUF24; Conserved hypothetical protein; transcriptional regulator 340760 4796636 llmg_0353 Lactococcus lactis subsp. cremoris MG1363 transcriptional regulator YP_001031706.1 340413 D 416870 CDS YP_001031707.1 125623224 4796979 340804..341196 1 NC_009004.1 Glyoxalase/extradiol ring-cleavage dioxygenase; Family membership; glyoxylase 341196 4796979 llmg_0354 Lactococcus lactis subsp. cremoris MG1363 glyoxylase YP_001031707.1 340804 D 416870 CDS YP_001031708.1 125623225 4797419 341375..342076 1 NC_009004.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 342076 gpmA 4797419 gpmA Lactococcus lactis subsp. cremoris MG1363 phosphoglyceromutase YP_001031708.1 341375 D 416870 CDS YP_001031709.1 125623226 4796669 342254..342817 1 NC_009004.1 High confidence in function and specificity; alkyl hydroperoxide reductase 342817 ahpC 4796669 ahpC Lactococcus lactis subsp. cremoris MG1363 alkyl hydroperoxide reductase YP_001031709.1 342254 D 416870 CDS YP_001031710.1 125623227 4796588 342883..344409 1 NC_009004.1 High confidence in function and specificity; alkyl hydroperoxide reductase 344409 ahpF 4796588 ahpF Lactococcus lactis subsp. cremoris MG1363 alkyl hydroperoxide reductase YP_001031710.1 342883 D 416870 CDS YP_001031711.1 125623228 4797509 344604..346769 1 NC_009004.1 High confidence in function and specificity; penicillin-binding protein 2B 346769 pbp2B 4797509 pbp2B Lactococcus lactis subsp. cremoris MG1363 penicillin-binding protein 2B YP_001031711.1 344604 D 416870 CDS YP_001031712.1 125623229 4798152 346899..347495 1 NC_009004.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 347495 recR 4798152 recR Lactococcus lactis subsp. cremoris MG1363 recombination protein RecR YP_001031712.1 346899 D 416870 CDS YP_001031713.1 125623230 4798238 347614..348663 1 NC_009004.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 348663 ddl 4798238 ddl Lactococcus lactis subsp. cremoris MG1363 D-alanyl-alanine synthetase A YP_001031713.1 347614 D 416870 CDS YP_001031714.1 125623231 4797461 348927..350249 1 NC_009004.1 D-Ala-D-Ala adding enzym; High confidence in function and specificity; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 350249 murF 4797461 murF Lactococcus lactis subsp. cremoris MG1363 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase YP_001031714.1 348927 D 416870 CDS YP_001031715.1 125623232 4796664 350418..352070 1 NC_009004.1 Conserved hypothetical protein; dipeptide-binding protein precursor 352070 dppA 4796664 dppA Lactococcus lactis subsp. cremoris MG1363 dipeptide-binding protein precursor YP_001031715.1 350418 D 416870 CDS YP_001031716.1 125623233 4798399 354096..355007 1 NC_009004.1 Conserved hypothetical protein; dipeptide transport system permease dppB 355007 dppB 4798399 dppB Lactococcus lactis subsp. cremoris MG1363 dipeptide transport system permease dppB YP_001031716.1 354096 D 416870 CDS YP_001031717.1 125623234 4796784 355023..356054 1 NC_009004.1 High confidence in function and specificity; dipeptide transport system permease dppC 356054 dppC 4796784 dppC Lactococcus lactis subsp. cremoris MG1363 dipeptide transport system permease dppC YP_001031717.1 355023 D 416870 CDS YP_001031718.1 125623235 4798365 356057..357106 1 NC_009004.1 High confidence in function and specificity; dipeptide transport ATP-binding protein dppD 357106 dppD 4798365 dppD Lactococcus lactis subsp. cremoris MG1363 dipeptide transport ATP-binding protein dppD YP_001031718.1 356057 D 416870 CDS YP_001031719.1 125623236 4798379 357106..358044 1 NC_009004.1 High confidence in function and specificity; dipeptide transport ATP-binding protein dppF 358044 dppF 4798379 dppF Lactococcus lactis subsp. cremoris MG1363 dipeptide transport ATP-binding protein dppF YP_001031719.1 357106 D 416870 CDS YP_001031720.1 125623237 4798388 358445..360016 1 NC_009004.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 360016 prfC 4798388 prfC Lactococcus lactis subsp. cremoris MG1363 peptide chain release factor 3 YP_001031720.1 358445 D 416870 CDS YP_001031721.1 125623238 4797126 360338..361993 1 NC_009004.1 Similar to cold-shock DEAD-box protein A (ATP- dependent RNA helicase deaD); High confidence in function and specificity; ATP-dependent RNA helicase 361993 rheA 4797126 rheA Lactococcus lactis subsp. cremoris MG1363 ATP-dependent RNA helicase YP_001031721.1 360338 D 416870 CDS YP_001031722.1 125623239 4796900 complement(362113..362202) 1 NC_009004.1 hypothetical protein 362202 4796900 llmg_0370 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031722.1 362113 R 416870 CDS YP_001031723.1 125623240 4797610 362691..363602 1 NC_009004.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 363602 era 4797610 era Lactococcus lactis subsp. cremoris MG1363 GTP-binding protein Era YP_001031723.1 362691 D 416870 CDS YP_001031724.1 125623241 4798548 363700..365292 1 NC_009004.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; asparagine synthetase B 365292 asnB 4798548 asnB Lactococcus lactis subsp. cremoris MG1363 asparagine synthetase B YP_001031724.1 363700 D 416870 CDS YP_001031725.1 125623242 4797219 365484..366302 1 NC_009004.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 366302 fpg 4797219 fpg Lactococcus lactis subsp. cremoris MG1363 formamidopyrimidine-DNA glycosylase YP_001031725.1 365484 D 416870 CDS YP_001031726.1 125623243 4797934 366455..367618 1 NC_009004.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 367618 recA 4797934 recA Lactococcus lactis subsp. cremoris MG1363 recombinase A YP_001031726.1 366455 D 416870 CDS YP_001031727.1 125623244 4796718 complement(367634..369016) 1 NC_009004.1 Specificity unclear; amino acid permease 369016 4796718 llmg_0375 Lactococcus lactis subsp. cremoris MG1363 amino acid permease YP_001031727.1 367634 R 416870 CDS YP_001031728.1 125623245 4796620 complement(369088..370467) 1 NC_009004.1 Specificity unclear; amino acid permease 370467 4796620 llmg_0376 Lactococcus lactis subsp. cremoris MG1363 amino acid permease YP_001031728.1 369088 R 416870 CDS YP_001031729.1 125623246 4796753 370614..370994 1 NC_009004.1 Protein of unknown function DUF1333; hypothetical protein 370994 4796753 llmg_0377 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031729.1 370614 D 416870 CDS YP_001031730.1 125623247 4798262 370969..371292 1 NC_009004.1 hypothetical protein 371292 4798262 llmg_0378 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031730.1 370969 D 416870 CDS YP_001031731.1 125623248 4798890 371516..372034 1 NC_009004.1 hypothetical protein 372034 4798890 llmg_0379 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031731.1 371516 D 416870 CDS YP_001031732.1 125623249 4798921 complement(372098..372691) 1 NC_009004.1 contains CYTH domain., Similar to adenylate cyclases; hypothetical protein 372691 4798921 llmg_0380 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031732.1 372098 R 416870 CDS YP_001031733.1 125623250 4797115 372911..373717 1 NC_009004.1 Protein of unknown function DUF817; Conserved hypothetical protein; hypothetical protein 373717 4797115 llmg_0381 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031733.1 372911 D 416870 CDS YP_001031734.1 125623251 4797902 373905..374564 1 NC_009004.1 Contains region found in RelA / SpoT proteins; Specificity unclear; GTP pyrophosphokinase 374564 4797902 llmg_0382 Lactococcus lactis subsp. cremoris MG1363 GTP pyrophosphokinase YP_001031734.1 373905 D 416870 CDS YP_001031735.1 125623252 4797928 374551..375363 1 NC_009004.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 375363 ppnK 4797928 ppnK Lactococcus lactis subsp. cremoris MG1363 inorganic polyphosphate/ATP-NAD kinase YP_001031735.1 374551 D 416870 CDS YP_001031736.1 125623253 4798239 375363..376244 1 NC_009004.1 High confidence in function and specificity; ribosomal large subunit pseudouridine synthase 376244 rluE 4798239 rluE Lactococcus lactis subsp. cremoris MG1363 ribosomal large subunit pseudouridine synthase YP_001031736.1 375363 D 416870 CDS YP_001031737.1 125623254 4797555 complement(376287..377120) 1 NC_009004.1 High confidence in function and specificity; cyclophilin type peptidyl-prolyl cis-trans isomerase 377120 ppiA 4797555 ppiA Lactococcus lactis subsp. cremoris MG1363 cyclophilin type peptidyl-prolyl cis-trans isomerase YP_001031737.1 376287 R 416870 CDS YP_001031738.1 125623255 4797084 377428..378861 1 NC_009004.1 Lysine specific permease; High confidence in function and specificity; amino-acid permease lysQ 378861 lysQ 4797084 lysQ Lactococcus lactis subsp. cremoris MG1363 amino-acid permease lysQ YP_001031738.1 377428 D 416870 CDS YP_001031739.1 125623256 4797153 379021..379824 1 NC_009004.1 Similar to NADPH-dependent FMN reductases; Family membership; hypothetical protein 379824 4797153 llmg_0387 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031739.1 379021 D 416870 CDS YP_001031740.1 125623257 4797950 379821..380798 1 NC_009004.1 ApbE-like lipoprotein; High confidence in function and specificity; thiamine biosynthesis lipoprotein apbE precursor 380798 apbE 4797950 apbE Lactococcus lactis subsp. cremoris MG1363 thiamine biosynthesis lipoprotein apbE precursor YP_001031740.1 379821 D 416870 CDS YP_001031741.1 125623258 4799123 complement(380881..382365) 1 NC_009004.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 382365 lysS 4799123 lysS Lactococcus lactis subsp. cremoris MG1363 lysyl-tRNA synthetase YP_001031741.1 380881 R 416870 CDS YP_001031742.1 125623259 4798512 complement(382562..383380) 1 NC_009004.1 High confidence in function and specificity; LysR family transcriptional regulator 383380 rlrG 4798512 rlrG Lactococcus lactis subsp. cremoris MG1363 LysR family transcriptional regulator YP_001031742.1 382562 R 416870 CDS YP_001031743.1 125623260 4798662 383544..384539 1 NC_009004.1 Region start changed from 383499 to 383544 (-45 bases); hypothetical protein 384539 4798662 llmg_0391 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031743.1 383544 D 416870 CDS YP_001031744.1 125623261 4797254 complement(384757..385701) 1 NC_009004.1 High confidence in function and specificity; L-lactate dehydrogenase 385701 ldhB 4797254 ldhB Lactococcus lactis subsp. cremoris MG1363 L-lactate dehydrogenase YP_001031744.1 384757 R 416870 CDS YP_001031745.1 125623262 4796655 complement(386016..386837) 1 NC_009004.1 High confidence in function and specificity; LysR family transcriptional regulator 386837 rlrD 4796655 rlrD Lactococcus lactis subsp. cremoris MG1363 LysR family transcriptional regulator YP_001031745.1 386016 R 416870 CDS YP_001031746.1 125623263 4797112 386993..387967 1 NC_009004.1 PF03595.4: C4-dicarboxylate transporter/malic acid transport protein; Family membership; permease 387967 4797112 llmg_0394 Lactococcus lactis subsp. cremoris MG1363 permease YP_001031746.1 386993 D 416870 CDS YP_001031747.1 125623264 4797328 388323..389543 1 NC_009004.1 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 389543 thiI 4797328 thiI Lactococcus lactis subsp. cremoris MG1363 thiamine biosynthesis protein ThiI YP_001031747.1 388323 D 416870 CDS YP_001031748.1 125623265 4797329 391309..391914 1 NC_009004.1 High confidence in function and specificity; NAD(P)H dehydrogenase (quinone) 391914 4797329 llmg_0397 Lactococcus lactis subsp. cremoris MG1363 NAD(P)H dehydrogenase (quinone) YP_001031748.1 391309 D 416870 CDS YP_001031749.1 125623266 4797881 392012..392446 1 NC_009004.1 PF02566.5: OsmC-like protein; hypothetical protein 392446 4797881 llmg_0398 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031749.1 392012 D 416870 CDS YP_001031750.1 125623267 4797175 complement(392501..394543) 1 NC_009004.1 High confidence in function and specificity; Na+/H+ antiporter 394543 nha 4797175 nha Lactococcus lactis subsp. cremoris MG1363 Na+/H+ antiporter YP_001031750.1 392501 R 416870 CDS YP_001031751.1 125623268 4797298 complement(394634..395104) 1 NC_009004.1 hypothetical protein 395104 4797298 llmg_0400 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031751.1 394634 R 416870 CDS YP_001031752.1 125623269 4797177 complement(395229..396488) 1 NC_009004.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 396488 tyrS 4797177 tyrS Lactococcus lactis subsp. cremoris MG1363 tyrosyl-tRNA synthetase YP_001031752.1 395229 R 416870 CDS YP_001031753.1 125623270 4797912 396633..399071 1 NC_009004.1 High confidence in function and specificity; penicillin-binding protein 1B 399071 pbp1B 4797912 pbp1B Lactococcus lactis subsp. cremoris MG1363 penicillin-binding protein 1B YP_001031753.1 396633 D 416870 CDS YP_001031754.1 125623271 4796852 complement(399112..400179) 1 NC_009004.1 High confidence in function and specificity; glutamyl-aminopeptidase 400179 pepA 4796852 pepA Lactococcus lactis subsp. cremoris MG1363 glutamyl-aminopeptidase YP_001031754.1 399112 R 416870 CDS YP_001031755.1 125623272 4798476 400282..400566 1 NC_009004.1 hypothetical protein 400566 4798476 llmg_0405 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031755.1 400282 D 416870 CDS YP_001031756.1 125623273 4797185 400611..400928 1 NC_009004.1 Thioredoxin domain 2; Conserved hypothetical protein; thioredoxin H-type 400928 trxH 4797185 trxH Lactococcus lactis subsp. cremoris MG1363 thioredoxin H-type YP_001031756.1 400611 D 416870 CDS YP_001031757.1 125623274 4797346 401034..401660 1 NC_009004.1 t-RNA-binding region; High confidence in function and specificity; phenylalanyl-tRNA synthetase beta chain 401660 pheT 4797346 pheT Lactococcus lactis subsp. cremoris MG1363 phenylalanyl-tRNA synthetase beta chain YP_001031757.1 401034 D 416870 CDS YP_001031758.1 125623275 4796799 401822..403162 1 NC_009004.1 FAD-dependent pyridine nucleotide-disulphide oxidoreductase, Pyridine nucleotide-disulphide oxidoreductase; High confidence in function and specificity; NADH oxidase 403162 noxE 4796799 noxE Lactococcus lactis subsp. cremoris MG1363 NADH oxidase YP_001031758.1 401822 D 416870 CDS YP_001031759.1 125623276 4798222 403253..403642 1 NC_009004.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 403642 ssbA 4798222 ssbA Lactococcus lactis subsp. cremoris MG1363 single-stranded DNA-binding protein YP_001031759.1 403253 D 416870 CDS YP_001031760.1 125623277 4798582 403761..404045 1 NC_009004.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 404045 groES 4798582 groES Lactococcus lactis subsp. cremoris MG1363 co-chaperonin GroES YP_001031760.1 403761 D 416870 CDS YP_001031761.1 125623278 4798738 404132..405760 1 NC_009004.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 405760 groEL 4798738 groEL Lactococcus lactis subsp. cremoris MG1363 molecular chaperone GroEL YP_001031761.1 404132 D 416870 CDS YP_001031762.1 125623279 4798732 complement(405810..406622) 1 NC_009004.1 Ribonuclease Z (tRNA 3 endonuclease)., Beta- lactamase-like, Metallo-beta-lactamase superfamily; High confidence in function and specificity; ribonuclease Z 406622 vicX 4798732 vicX Lactococcus lactis subsp. cremoris MG1363 ribonuclease Z YP_001031762.1 405810 R 416870 CDS YP_001031763.1 125623280 4798420 complement(406813..408240) 1 NC_009004.1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, cztS_silS_copS: heavy metal sensor kinase; High confidence in function and specificity; sensor histidine kinase 408240 kinC 4798420 kinC Lactococcus lactis subsp. cremoris MG1363 sensor histidine kinase YP_001031763.1 406813 R 416870 CDS YP_001031764.1 125623281 4797664 complement(408233..408934) 1 NC_009004.1 Response regulator receiver domain, PhoB: Phosphate regulon transcriptional regulatory protein phoB; Conserved hypothetical protein; two-component system regulator 408934 llrC 4797664 llrC Lactococcus lactis subsp. cremoris MG1363 two-component system regulator YP_001031764.1 408233 R 416870 CDS YP_001031765.1 125623282 4796610 409112..409747 1 NC_009004.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 409747 tmk 4796610 tmk Lactococcus lactis subsp. cremoris MG1363 thymidylate kinase YP_001031765.1 409112 D 416870 CDS YP_001031766.1 125623283 4797098 409880..410740 1 NC_009004.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA.; DNA polymerase III subunit delta' 410740 holB 4797098 holB Lactococcus lactis subsp. cremoris MG1363 DNA polymerase III subunit delta' YP_001031766.1 409880 D 416870 CDS YP_001031767.1 125623284 4796639 410790..411572 1 NC_009004.1 PSP1 C-terminal conserved region; High confidence in function and specificity; hypothetical protein 411572 4796639 llmg_0417 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031767.1 410790 D 416870 CDS YP_001031768.1 125623285 4797297 411565..411891 1 NC_009004.1 in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA; DNA replication intiation control protein YabA 411891 4797297 llmg_0418 Lactococcus lactis subsp. cremoris MG1363 DNA replication intiation control protein YabA YP_001031768.1 411565 D 416870 CDS YP_001031769.1 125623286 4798008 411891..412766 1 NC_009004.1 Tetrapyrrole (Corrin/Porphyrin) Methylases; hypothetical protein 412766 4798008 llmg_0419 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031769.1 411891 D 416870 CDS YP_001031770.1 125623287 4797267 complement(412844..413035) 1 NC_009004.1 hypothetical protein 413035 4797267 llmg_0420 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031770.1 412844 R 416870 CDS YP_001031771.1 125623288 4797967 complement(413110..413922) 1 NC_009004.1 Belongs to the ABC-2 integral membrane protein family; Conserved hypothetical protein; daunorubicin resistance transmembrane protein 413922 drrB 4797967 drrB Lactococcus lactis subsp. cremoris MG1363 daunorubicin resistance transmembrane protein YP_001031771.1 413110 R 416870 CDS YP_001031772.1 125623289 4798376 complement(413935..414072) 1 NC_009004.1 hypothetical protein 414072 4798376 llmg_0422 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031772.1 413935 R 416870 CDS YP_001031773.1 125623290 4797810 complement(414082..414864) 1 NC_009004.1 High confidence in function and specificity; daunorubicin resistance ABC transporter ATP-binding subunit 414864 drrA 4797810 drrA Lactococcus lactis subsp. cremoris MG1363 daunorubicin resistance ABC transporter ATP-binding subunit YP_001031773.1 414082 R 416870 CDS YP_001031774.1 125623291 4798362 414996..415496 1 NC_009004.1 Transcriptional regulator , Cytolysin slyA, InterPro: Bacterial regulatory protein, MarR; High confidence in function and specificity; transcriptional regulator 415496 4798362 llmg_0424 Lactococcus lactis subsp. cremoris MG1363 transcriptional regulator YP_001031774.1 414996 D 416870 CDS YP_001031775.1 125623292 4798261 complement(415627..416559) 1 NC_009004.1 Mevalonate kinase, GHMP kinases ATP- binding protein, mevalon_kin: mevalonate kinase; High confidence in function and specificity; mevalonate kinase 416559 mvk 4798261 mvk Lactococcus lactis subsp. cremoris MG1363 mevalonate kinase YP_001031775.1 415627 R 416870 CDS YP_001031776.1 125623293 4796736 416868..417824 1 NC_009004.1 Diphosphomevalonate decarboxylase, GHMP kinases ATP-binding protein, mevDPdecarb: diphosphomevalonate decarboxylase; High confidence in function and specificity; diphosphomevalonate decarboxylase 417824 mvaD 4796736 mvaD Lactococcus lactis subsp. cremoris MG1363 diphosphomevalonate decarboxylase YP_001031776.1 416868 D 416870 CDS YP_001031777.1 125623294 4798562 417811..418800 1 NC_009004.1 GHMP kinases ATP-binding protein; High confidence in function and specificity; phosphomevalonate kinase 418800 4798562 llmg_0427 Lactococcus lactis subsp. cremoris MG1363 phosphomevalonate kinase YP_001031777.1 417811 D 416870 CDS YP_001031778.1 125623295 4798189 418923..419972 1 NC_009004.1 catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate; isopentenyl pyrophosphate isomerase 419972 fni 4798189 fni Lactococcus lactis subsp. cremoris MG1363 isopentenyl pyrophosphate isomerase YP_001031778.1 418923 D 416870 CDS YP_001031779.1 125623296 4796682 420126..420746 1 NC_009004.1 Manganese and iron superoxide dismutase, Iron/manganese superoxide dismutases, C-terminal domain; High confidence in function and specificity; SodA protein 420746 sodA 4796682 sodA Lactococcus lactis subsp. cremoris MG1363 SodA protein YP_001031779.1 420126 D 416870 CDS YP_001031780.1 125623297 4798951 420997..423351 1 NC_009004.1 Carbon starvation protein CstA; Conserved hypothetical protein; carbon starvation protein A 423351 cstA 4798951 cstA Lactococcus lactis subsp. cremoris MG1363 carbon starvation protein A YP_001031780.1 420997 D 416870 CDS YP_001031781.1 125623298 4798838 complement(423532..424191) 1 NC_009004.1 Region start changed from 424275 to 424191 (-84 bases); acyl carrier protein phosphodiesterase 2 424191 4798838 llmg_0431 Lactococcus lactis subsp. cremoris MG1363 acyl carrier protein phosphodiesterase 2 YP_001031781.1 423532 R 416870 CDS YP_001031782.1 125623299 4797094 424278..425216 1 NC_009004.1 transcriptional regulator 425216 4797094 llmg_0432 Lactococcus lactis subsp. cremoris MG1363 transcriptional regulator YP_001031782.1 424278 D 416870 CDS YP_001031783.1 125623300 4798242 425365..426705 1 NC_009004.1 DEAD/DEAH box helicase; ATP-dependent RNA helicase 426705 rheB 4798242 rheB Lactococcus lactis subsp. cremoris MG1363 ATP-dependent RNA helicase YP_001031783.1 425365 D 416870 CDS YP_001031784.1 125623301 4798201 426709..427293 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 427293 4798201 llmg_0434 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031784.1 426709 D 416870 CDS YP_001031785.1 125623302 4798495 427409..428155 1 NC_009004.1 Contains 1 HTH rpiR-type DNA-binding domain; Conserved hypothetical protein; HTH-type transcriptional regulator 428155 hexR 4798495 hexR Lactococcus lactis subsp. cremoris MG1363 HTH-type transcriptional regulator YP_001031785.1 427409 D 416870 CDS YP_001031786.1 125623303 4797585 428133..428228 1 NC_009004.1 hypothetical protein 428228 4797585 llmg_0436 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031786.1 428133 D 416870 CDS YP_001031787.1 125623304 4797109 428397..428723 1 NC_009004.1 Lichenan- permease IIB component, Phosphotransferase system, lactose/cellobiose-specific IIB subunit, PTS system, Lactose/Cellobiose specific IIB subunit; High confidence in function and specificity; cellobiose-specific PTS system IIB component 428723 ptcB 4797109 ptcB Lactococcus lactis subsp. cremoris MG1363 cellobiose-specific PTS system IIB component YP_001031787.1 428397 D 416870 CDS YP_001031788.1 125623305 4798642 428806..429156 1 NC_009004.1 PTS system, lactose-specific IIA component , Lactose- permease IIA component, Phosphotransferase system PTS, lactose/cellobiose-specific IIA subunit, PTS system, Lactose/Cellobiose specific IIA subunit; High confidence in function and specificity; cellobiose-specific PTS system IIA component 429156 ptcA 4798642 ptcA Lactococcus lactis subsp. cremoris MG1363 cellobiose-specific PTS system IIA component YP_001031788.1 428806 D 416870 CDS YP_001031789.1 125623306 4798730 429250..429978 1 NC_009004.1 Family membership; LacI family transcriptional regulator 429978 4798730 llmg_0439 Lactococcus lactis subsp. cremoris MG1363 LacI family transcriptional regulator YP_001031789.1 429250 D 416870 CDS YP_001031790.1 125623307 4796893 430271..431608 1 NC_009004.1 PTS system, lichenan-specific IIC component; High confidence in function and specificity; cellobiose-specific PTS system IIC component 431608 ptcC 4796893 ptcC Lactococcus lactis subsp. cremoris MG1363 cellobiose-specific PTS system IIC component YP_001031790.1 430271 D 416870 CDS YP_001031791.1 125623308 4798119 431698..433134 1 NC_009004.1 converts 6-phospho-beta-D-glucosyl-(1,4)-D-glucose to glucose and glucose 6-phosphate; required for cellobiose uptake and metabolism; 6-phospho-beta-glucosidase 433134 celA 4798119 celA Lactococcus lactis subsp. cremoris MG1363 6-phospho-beta-glucosidase YP_001031791.1 431698 D 416870 CDS YP_001031792.1 125623309 4798650 433420..433701 1 NC_009004.1 hypothetical protein 433701 4798650 llmg_0442 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031792.1 433420 D 416870 CDS YP_001031793.1 125623310 4797471 433884..434060 1 NC_009004.1 hypothetical protein 434060 4797471 llmg_0443 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031793.1 433884 D 416870 CDS YP_001031794.1 125623311 4798183 434066..436126 1 NC_009004.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 436126 ligA 4798183 ligA Lactococcus lactis subsp. cremoris MG1363 NAD-dependent DNA ligase LigA YP_001031794.1 434066 D 416870 CDS YP_001031795.2 162329651 4796597 436267..437298 1 NC_009004.1 similar to YegS from E. coli; lipid kinase 437298 4796597 llmg_0445 Lactococcus lactis subsp. cremoris MG1363 lipid kinase YP_001031795.2 436267 D 416870 CDS YP_001031796.1 125623313 4797024 437518..438654 1 NC_009004.1 Probable multiple sugar-binding transport ATP- binding protein; Conserved hypothetical protein; multiple sugar-binding transport ATP-binding protein 438654 msmK 4797024 msmK Lactococcus lactis subsp. cremoris MG1363 multiple sugar-binding transport ATP-binding protein YP_001031796.1 437518 D 416870 CDS YP_001031797.1 125623314 4797183 438961..442632 1 NC_009004.1 Pyruvate:ferredoxin (flavodoxin) oxidoreductase, Thiamine pyrophosphate enzyme, C-terminal TPP binding domain, pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase; High confidence in function and specificity; NifJ protein 442632 nifJ 4797183 nifJ Lactococcus lactis subsp. cremoris MG1363 NifJ protein YP_001031797.1 438961 D 416870 CDS YP_001031798.1 125623315 4797258 442807..443685 1 NC_009004.1 hypothetical protein 443685 4797258 llmg_0448 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031798.1 442807 D 416870 CDS YP_001031799.1 125623316 4798231 443675..443962 1 NC_009004.1 hypothetical protein 443962 4798231 llmg_0449 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031799.1 443675 D 416870 CDS YP_001031800.1 125623317 4797071 443980..444633 1 NC_009004.1 hypothetical protein 444633 4797071 llmg_0450 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031800.1 443980 D 416870 CDS YP_001031801.1 125623318 4798497 444678..446036 1 NC_009004.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 446036 glmM 4798497 glmM Lactococcus lactis subsp. cremoris MG1363 phosphoglucosamine mutase YP_001031801.1 444678 D 416870 CDS YP_001031802.1 125623319 4797118 complement(446110..446826) 1 NC_009004.1 GntR family transcriptional regulator; Conserved hypothetical protein; trehalose operon transcriptional repressor 446826 treR 4797118 treR Lactococcus lactis subsp. cremoris MG1363 trehalose operon transcriptional repressor YP_001031802.1 446110 R 416870 CDS YP_001031803.1 125623320 4797778 446937..447422 1 NC_009004.1 PTS system likely trehalose specific; High confidence in function and specificity; sucrose-specific PTS enzyme IIABC 447422 4797778 llmg_0453 Lactococcus lactis subsp. cremoris MG1363 sucrose-specific PTS enzyme IIABC YP_001031803.1 446937 D 416870 CDS YP_001031804.1 125623321 4797093 447563..449128 1 NC_009004.1 PTS-IIBC-Tre: PTS system, trehalose-specific IIBC component; High confidence in function and specificity; beta-glucoside-specific PTS system IIABC component 449128 4797093 llmg_0454 Lactococcus lactis subsp. cremoris MG1363 beta-glucoside-specific PTS system IIABC component YP_001031804.1 447563 D 416870 CDS YP_001031805.1 125623322 4797140 449195..451504 1 NC_009004.1 Glycoside transferase, six-hairpin, Glycosyl hydrolase 65 central catalytic domain; High confidence in function and specificity; trehalose/maltose hydrolase 451504 trePP 4797140 trePP Lactococcus lactis subsp. cremoris MG1363 trehalose/maltose hydrolase YP_001031805.1 449195 D 416870 CDS YP_001031806.1 125623323 4797271 451657..452322 1 NC_009004.1 haloacid dehalogenase-like hydrolase, bPGM: beta- phosphoglucomutase; High confidence in function and specificity; beta-phosphoglucomutase 452322 pgmB 4797271 pgmB Lactococcus lactis subsp. cremoris MG1363 beta-phosphoglucomutase YP_001031806.1 451657 D 416870 CDS YP_001031807.1 125623324 4798403 complement(452381..453148) 1 NC_009004.1 PS50187: Esterase/lipase/thioesterase; Family membership; lipase/esterase 453148 4798403 llmg_0457 Lactococcus lactis subsp. cremoris MG1363 lipase/esterase YP_001031807.1 452381 R 416870 CDS YP_001031808.1 125623325 4797058 453258..453956 1 NC_009004.1 High confidence in function and specificity; hypothetical protein 453956 4797058 llmg_0458 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031808.1 453258 D 416870 CDS YP_001031809.1 125623326 4797101 454115..454561 1 NC_009004.1 Uncharacterised P-loop hydrolase UPF0079; hypothetical protein 454561 4797101 llmg_0459 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031809.1 454115 D 416870 CDS YP_001031810.1 125623327 4796988 454558..455076 1 NC_009004.1 GCN5-related N-acetyltransferase, Acetyltransferase (GNAT) family; Conserved hypothetical protein; acetyltransferase 455076 4796988 llmg_0460 Lactococcus lactis subsp. cremoris MG1363 acetyltransferase YP_001031810.1 454558 D 416870 CDS YP_001031811.1 125623328 4796877 455181..456560 1 NC_009004.1 Cell envelope-related transcriptional attenuator domain, lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain; Conserved hypothetical protein; transcriptional regulator 456560 lytR 4796877 lytR Lactococcus lactis subsp. cremoris MG1363 transcriptional regulator YP_001031811.1 455181 D 416870 CDS YP_001031812.1 125623329 4797597 456961..457722 1 NC_009004.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 457722 truA 4797597 truA Lactococcus lactis subsp. cremoris MG1363 tRNA pseudouridine synthase A YP_001031812.1 456961 D 416870 CDS YP_001031813.1 125623330 4798726 457756..458544 1 NC_009004.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 458544 thiD2 4798726 thiD2 Lactococcus lactis subsp. cremoris MG1363 phosphomethylpyrimidine kinase YP_001031813.1 457756 D 416870 CDS YP_001031814.1 125623331 4797018 458584..459084 1 NC_009004.1 High confidence in function and specificity; hypothetical protein 459084 4797018 llmg_0464 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031814.1 458584 D 416870 CDS YP_001031815.1 125623332 4796885 459065..459607 1 NC_009004.1 hypothetical protein 459607 4796885 llmg_0465 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031815.1 459065 D 416870 CDS YP_001031816.1 125623333 4796851 459608..460744 1 NC_009004.1 Serine--pyruvate aminotransferase , (SPT) (Alanine-- glyoxylate aminotransferase)(AGT)., Aminotransferase, class V; High confidence in function and specificity; aminotransferase 460744 aspC 4796851 aspC Lactococcus lactis subsp. cremoris MG1363 aminotransferase YP_001031816.1 459608 D 416870 CDS YP_001031817.1 125623334 4798405 461021..462628 1 NC_009004.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 462628 pyrG 4798405 pyrG Lactococcus lactis subsp. cremoris MG1363 CTP synthetase YP_001031817.1 461021 D 416870 CDS YP_001031818.1 125623335 4798463 462840..463676 1 NC_009004.1 hypothetical protein 463676 4798463 llmg_0468 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031818.1 462840 D 416870 CDS YP_001031819.1 125623336 4799128 463673..464230 1 NC_009004.1 hypothetical protein 464230 4799128 llmg_0469 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031819.1 463673 D 416870 CDS YP_001031820.1 125623337 4799131 464462..465343 1 NC_009004.1 domain: Collagen alpha 1(XVII); High confidence in function and specificity; hypothetical protein 465343 4799131 llmg_0470 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031820.1 464462 D 416870 CDS YP_001031821.1 125623338 4796593 465350..465922 1 NC_009004.1 hypothetical protein 465922 4796593 llmg_0471 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031821.1 465350 D 416870 CDS YP_001031822.1 125623339 4797494 465930..466493 1 NC_009004.1 hypothetical protein 466493 4797494 llmg_0472 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031822.1 465930 D 416870 CDS YP_001031823.1 125623340 4796641 466853..467446 1 NC_009004.1 hypothetical protein 467446 4796641 llmg_0473 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031823.1 466853 D 416870 CDS YP_001031824.1 125623341 4796570 467450..467908 1 NC_009004.1 hypothetical protein 467908 4796570 llmg_0474 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031824.1 467450 D 416870 CDS YP_001031825.1 125623342 4797434 467926..468840 1 NC_009004.1 Similar to ldhB; Specificity unclear; malate/lactate dehydrogenase 468840 4797434 llmg_0475 Lactococcus lactis subsp. cremoris MG1363 malate/lactate dehydrogenase YP_001031825.1 467926 D 416870 CDS YP_001031826.1 125623343 4796638 complement(468875..469747) 1 NC_009004.1 Protein of unknown function DUF1003; Conserved hypothetical protein; hypothetical protein 469747 4796638 llmg_0476 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031826.1 468875 R 416870 CDS YP_001031827.1 125623344 4796712 complement(470104..470304) 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 470304 4796712 llmg_0477 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031827.1 470104 R 416870 CDS YP_001031828.1 125623345 4797485 complement(470360..470872) 1 NC_009004.1 Family membership; nucleoside deoxyribosyltransferase 470872 ntd 4797485 ntd Lactococcus lactis subsp. cremoris MG1363 nucleoside deoxyribosyltransferase YP_001031828.1 470360 R 416870 CDS YP_001031829.1 125623346 4797270 complement(470856..471410) 1 NC_009004.1 TIGR00730: conserved hypothetical protein; hypothetical protein 471410 4797270 llmg_0479 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031829.1 470856 R 416870 CDS YP_001031830.1 125623347 4797488 complement(471410..472063) 1 NC_009004.1 High confidence in function and specificity; deoxyguanosine kinase 472063 dukA 4797488 dukA Lactococcus lactis subsp. cremoris MG1363 deoxyguanosine kinase YP_001031830.1 471410 R 416870 CDS YP_001031831.1 125623348 4798944 472626..473660 1 NC_009004.1 PF03412.4: Peptidase C39, bacteriocin processing; hypothetical protein 473660 4798944 llmg_0481 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031831.1 472626 D 416870 CDS YP_001031832.1 125623349 4797412 473713..474897 1 NC_009004.1 hypothetical protein 474897 4797412 llmg_0482 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031832.1 473713 D 416870 CDS YP_001031833.1 125623350 4797492 475040..478252 1 NC_009004.1 Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria.; DNA polymerase III DnaE 478252 dnaE 4797492 dnaE Lactococcus lactis subsp. cremoris MG1363 DNA polymerase III DnaE YP_001031833.1 475040 D 416870 CDS YP_001031834.1 125623351 4798382 478340..479329 1 NC_009004.1 Function unclear; LacI family transcriptional regulator 479329 4798382 llmg_0484 Lactococcus lactis subsp. cremoris MG1363 LacI family transcriptional regulator YP_001031834.1 478340 D 416870 CDS YP_001031835.1 125623352 4796967 479423..479818 1 NC_009004.1 PF06271.1: RDD family protein, contains AL9 export element; Family membership; hypothetical protein 479818 4796967 llmg_0485 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031835.1 479423 D 416870 CDS YP_001031836.1 125623353 4799127 479811..480086 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 480086 4799127 llmg_0486 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031836.1 479811 D 416870 CDS YP_001031837.1 125623354 4797621 480171..482471 1 NC_009004.1 Glycoside transferase, six-hairpin, Glycosyl hydrolase 65 central catalytic domain; Specificity unclear; trehalose/maltose hydrolase 482471 4797621 llmg_0487 Lactococcus lactis subsp. cremoris MG1363 trehalose/maltose hydrolase YP_001031837.1 480171 D 416870 CDS YP_001031838.1 125623355 4796601 482525..483790 1 NC_009004.1 Specificity unclear; multiple sugar-binding protein 483790 4796601 llmg_0488 Lactococcus lactis subsp. cremoris MG1363 multiple sugar-binding protein YP_001031838.1 482525 D 416870 CDS YP_001031839.1 125623356 4796717 483966..484841 1 NC_009004.1 Specificity unclear; sugar transport system permease 484841 4796717 llmg_0489 Lactococcus lactis subsp. cremoris MG1363 sugar transport system permease YP_001031839.1 483966 D 416870 CDS YP_001031840.1 125623357 4796719 484822..485673 1 NC_009004.1 Specificity unclear; sugar transport system permease 485673 4796719 llmg_0490 Lactococcus lactis subsp. cremoris MG1363 sugar transport system permease YP_001031840.1 484822 D 416870 CDS YP_001031841.1 125623358 4796613 complement(485703..486356) 1 NC_009004.1 High confidence in function and specificity; hemolysin like protein 486356 hly 4796613 hly Lactococcus lactis subsp. cremoris MG1363 hemolysin like protein YP_001031841.1 485703 R 416870 CDS YP_001031842.1 125623359 4796596 486558..487394 1 NC_009004.1 PF02645.5: degV family protein; Family membership; hypothetical protein 487394 4796596 llmg_0492 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031842.1 486558 D 416870 CDS YP_001031843.1 125623360 4796768 487449..488288 1 NC_009004.1 PF00657.10: GDSL-like Lipase/Acylhydrolase; Family membership; esterase 488288 4796768 llmg_0493 Lactococcus lactis subsp. cremoris MG1363 esterase YP_001031843.1 487449 D 416870 CDS YP_001031844.1 125623361 4797619 488285..489505 1 NC_009004.1 High confidence in function and specificity; beta-N-acetylglucosaminidase 489505 nagZ 4797619 nagZ Lactococcus lactis subsp. cremoris MG1363 beta-N-acetylglucosaminidase YP_001031844.1 488285 D 416870 CDS YP_001031845.1 125623362 4798657 489514..490170 1 NC_009004.1 hypothetical protein 490170 4798657 llmg_0495 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031845.1 489514 D 416870 CDS YP_001031846.1 125623363 4797353 490275..490550 1 NC_009004.1 Histone-like bacterial DNA-binding protein; High confidence in function and specificity; HU-like DNA-binding protein 490550 hllA 4797353 hllA Lactococcus lactis subsp. cremoris MG1363 HU-like DNA-binding protein YP_001031846.1 490275 D 416870 CDS YP_001031847.1 125623364 4796659 complement(490661..491158) 1 NC_009004.1 GCN5-related N-acetyltransferase; Family membership; hypothetical protein 491158 4796659 llmg_0497 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031847.1 490661 R 416870 CDS YP_001031848.1 125623365 4799036 491341..491850 1 NC_009004.1 Methylated-DNA--protein-cysteine methyltransferase; High confidence in function and specificity; 6-O-methylguanine DNA methyltransferase 491850 ogt 4799036 ogt Lactococcus lactis subsp. cremoris MG1363 6-O-methylguanine DNA methyltransferase YP_001031848.1 491341 D 416870 CDS YP_001031849.1 125623366 4799094 491865..492413 1 NC_009004.1 High confidence in function and specificity; methylphosphotriester-DNA alkyltransferase 492413 adaA 4799094 adaA Lactococcus lactis subsp. cremoris MG1363 methylphosphotriester-DNA alkyltransferase YP_001031849.1 491865 D 416870 CDS YP_001031850.1 125623367 4798917 492425..493228 1 NC_009004.1 High confidence in function and specificity; arylamine N-acetyltransferase 2 493228 nhoA 4798917 nhoA Lactococcus lactis subsp. cremoris MG1363 arylamine N-acetyltransferase 2 YP_001031850.1 492425 D 416870 CDS YP_001031851.1 125623368 4798049 493375..494184 1 NC_009004.1 Specificity unclear; ABC transporter ATP-binding protein 494184 4798049 llmg_0501 Lactococcus lactis subsp. cremoris MG1363 ABC transporter ATP-binding protein YP_001031851.1 493375 D 416870 CDS YP_001031852.1 125623369 4798190 494181..494906 1 NC_009004.1 Specificity unclear; ABC transporter permease 494906 4798190 llmg_0502 Lactococcus lactis subsp. cremoris MG1363 ABC transporter permease YP_001031852.1 494181 D 416870 CDS YP_001031853.1 125623370 4798212 494968..495426 1 NC_009004.1 PF04397.5: LytTr DNA-binding domain; Conserved hypothetical protein; LytR family transcriptional regulator 495426 4798212 llmg_0503 Lactococcus lactis subsp. cremoris MG1363 LytR family transcriptional regulator YP_001031853.1 494968 D 416870 CDS YP_001031854.1 125623371 4797116 495423..495800 1 NC_009004.1 hypothetical protein 495800 4797116 llmg_0504 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031854.1 495423 D 416870 CDS YP_001031855.1 125623372 4797029 495909..497054 1 NC_009004.1 Aminotransferase class-V; High confidence in function and specificity; pyridoxal-phosphate dependent aminotransferase 497054 nifZ 4797029 nifZ Lactococcus lactis subsp. cremoris MG1363 pyridoxal-phosphate dependent aminotransferase YP_001031855.1 495909 D 416870 CDS YP_001031856.1 125623373 4797885 497205..498083 1 NC_009004.1 PF00877.9: NLP/P60 domain; Function unclear; hypothetical protein 498083 4797885 llmg_0506 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031856.1 497205 D 416870 CDS YP_001031857.1 125623374 4796918 complement(498140..499789) 1 NC_009004.1 Similar to oligopeptide ABC transporter substrate binding proteins; Conserved hypothetical protein; peptide binding protein 499789 4796918 llmg_0507 Lactococcus lactis subsp. cremoris MG1363 peptide binding protein YP_001031857.1 498140 R 416870 CDS YP_001031858.1 125623375 4797035 complement(499981..500913) 1 NC_009004.1 Region start changed from 500979 to 500913 (-66 bases); cysteine synthase 500913 4797035 llmg_0508 Lactococcus lactis subsp. cremoris MG1363 cysteine synthase YP_001031858.1 499981 R 416870 CDS YP_001031859.1 125623376 4796821 501132..502217 1 NC_009004.1 High confidence in function and specificity; N-acetylglucosaminidase 502217 acmD 4796821 acmD Lactococcus lactis subsp. cremoris MG1363 N-acetylglucosaminidase YP_001031859.1 501132 D 416870 CDS YP_001031860.1 125623377 4798885 complement(502253..502885) 1 NC_009004.1 Metallo-beta-lactamase superfamily; Family membership; Zn-dependent hydrolase 502885 4798885 llmg_0510 Lactococcus lactis subsp. cremoris MG1363 Zn-dependent hydrolase YP_001031860.1 502253 R 416870 CDS YP_001031861.1 125623378 4797936 complement(502886..504967) 1 NC_009004.1 penicillin-binding protein 1a 504967 ponA 4797936 ponA Lactococcus lactis subsp. cremoris MG1363 penicillin-binding protein 1a YP_001031861.1 502886 R 416870 CDS YP_001031862.1 125623379 4796592 complement(504954..505595) 1 NC_009004.1 functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC; Holliday junction-specific endonuclease 505595 recU 4796592 recU Lactococcus lactis subsp. cremoris MG1363 Holliday junction-specific endonuclease YP_001031862.1 504954 R 416870 CDS YP_001031863.1 125623380 4797089 505676..506200 1 NC_009004.1 Protein of unknown function DUF1273; hypothetical protein 506200 4797089 llmg_0513 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031863.1 505676 D 416870 CDS YP_001031864.1 125623381 4797165 506345..506746 1 NC_009004.1 Similar to regulatory protein spx; hypothetical protein 506746 4797165 llmg_0514 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031864.1 506345 D 416870 CDS YP_001031865.1 125623382 4797194 506967..507248 1 NC_009004.1 Uncharacterised protein family (UPF0223); hypothetical protein 507248 4797194 llmg_0515 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031865.1 506967 D 416870 CDS YP_001031866.1 125623383 4798314 507232..507993 1 NC_009004.1 Inositol monophosphatase; High confidence in function and specificity; myo-inositol-1(or 4)-monophosphatase 507993 suhB 4798314 suhB Lactococcus lactis subsp. cremoris MG1363 myo-inositol-1(or 4)-monophosphatase YP_001031866.1 507232 D 416870 CDS YP_001031867.1 125623384 4798608 508088..509368 1 NC_009004.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 509368 murA2 4798608 murA2 Lactococcus lactis subsp. cremoris MG1363 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_001031867.1 508088 D 416870 CDS YP_001031868.1 125623385 4797477 509368..509559 1 NC_009004.1 hypothetical protein 509559 4797477 llmg_0518 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031868.1 509368 D 416870 CDS YP_001031869.1 125623386 4797884 509736..511019 1 NC_009004.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 511019 tig 4797884 tig Lactococcus lactis subsp. cremoris MG1363 trigger factor YP_001031869.1 509736 D 416870 CDS YP_001031870.1 125623387 4796955 517878..519791 1 NC_009004.1 synthesizes RNA primers at the replication forks; DNA primase 519791 dnaG 4796955 dnaG Lactococcus lactis subsp. cremoris MG1363 DNA primase YP_001031870.1 517878 D 416870 CDS YP_001031871.1 125623388 4798386 519868..521211 1 NC_009004.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium; RNA polymerase sigma factor RpoD 521211 rpoD 4798386 rpoD Lactococcus lactis subsp. cremoris MG1363 RNA polymerase sigma factor RpoD YP_001031871.1 519868 D 416870 CDS YP_001031872.1 125623389 4796785 521309..522052 1 NC_009004.1 contains sugar isomerase domain PF01380.10; Function unclear; transcriptional regulator 522052 4796785 llmg_0522 Lactococcus lactis subsp. cremoris MG1363 transcriptional regulator YP_001031872.1 521309 D 416870 CDS YP_001031873.1 125623390 4798527 522209..523588 1 NC_009004.1 Major Facilitator Superfamily; High confidence in function and specificity; glycerol-3-phosphatase transporter 523588 glpT 4798527 glpT Lactococcus lactis subsp. cremoris MG1363 glycerol-3-phosphatase transporter YP_001031873.1 522209 D 416870 CDS YP_001031874.1 125623391 4797378 523744..524346 1 NC_009004.1 hypothetical protein 524346 4797378 llmg_0524 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031874.1 523744 D 416870 CDS YP_001031875.1 125623392 4797553 524418..524612 1 NC_009004.1 hypothetical protein 524612 4797553 llmg_0525 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031875.1 524418 D 416870 CDS YP_001031876.1 125623393 4798948 524622..525887 1 NC_009004.1 hypothetical protein 525887 4798948 llmg_0526 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031876.1 524622 D 416870 CDS YP_001031877.1 125623394 4798954 526116..526460 1 NC_009004.1 hypothetical protein 526460 4798954 llmg_0527 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031877.1 526116 D 416870 CDS YP_001031878.1 125623395 4797303 526506..528752 1 NC_009004.1 ATPase associated with various cellular activities (AAA); High confidence in function and specificity; ATP-dependent Clp protease ATP-binding subunit clpE 528752 clpE 4797303 clpE Lactococcus lactis subsp. cremoris MG1363 ATP-dependent Clp protease ATP-binding subunit clpE YP_001031878.1 526506 D 416870 CDS YP_001031879.1 125623396 4796958 complement(528887..529357) 1 NC_009004.1 Protein of unknown function UPF0074, rrf2_super: rrf2 family protein; Family membership; transcriptional regulator 529357 4796958 llmg_0529 Lactococcus lactis subsp. cremoris MG1363 transcriptional regulator YP_001031879.1 528887 R 416870 CDS YP_001031880.1 125623397 4797280 529583..530596 1 NC_009004.1 Glyceraldehyde-3-phosphate dehydrogenase, type I; High confidence in function and specificity; glyceraldehyde 3-phosphate dehydrogenase 530596 gapA 4797280 gapA Lactococcus lactis subsp. cremoris MG1363 glyceraldehyde 3-phosphate dehydrogenase YP_001031880.1 529583 D 416870 CDS YP_001031881.1 125623398 4797681 complement(530629..530805) 1 NC_009004.1 hypothetical protein 530805 4797681 llmg_0531 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031881.1 530629 R 416870 CDS YP_001031882.1 125623399 4798299 complement(530821..531456) 1 NC_009004.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 531456 def 4798299 def Lactococcus lactis subsp. cremoris MG1363 peptide deformylase YP_001031882.1 530821 R 416870 CDS YP_001031883.1 125623400 4798048 531611..532066 1 NC_009004.1 hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 532066 nudH 4798048 nudH Lactococcus lactis subsp. cremoris MG1363 dinucleoside polyphosphate hydrolase YP_001031883.1 531611 D 416870 CDS YP_001031884.1 125623401 4798741 532077..534155 1 NC_009004.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 534155 uvrB 4798741 uvrB Lactococcus lactis subsp. cremoris MG1363 excinuclease ABC subunit B YP_001031884.1 532077 D 416870 CDS YP_001031885.1 125623402 4797326 534338..535159 1 NC_009004.1 Bacterial extracellular solute-binding protein, family 3; High confidence in function and specificity; arginine/ornithine ABC transporter substrate-binding protein 535159 gltS 4797326 gltS Lactococcus lactis subsp. cremoris MG1363 arginine/ornithine ABC transporter substrate-binding protein YP_001031885.1 534338 D 416870 CDS YP_001031886.1 125623403 4798832 535174..536295 1 NC_009004.1 High confidence in function and specificity; acetylornithine deacetylase 536295 argE 4798832 argE Lactococcus lactis subsp. cremoris MG1363 acetylornithine deacetylase YP_001031886.1 535174 D 416870 CDS YP_001031887.1 125623404 4799047 complement(536347..536802) 1 NC_009004.1 CDS; (3R)-hydroxymyristoyl-ACP dehydratase 536802 4799047 llmg_0538 Lactococcus lactis subsp. cremoris MG1363 (3R)-hydroxymyristoyl-ACP dehydratase YP_001031887.1 536347 R 416870 CDS YP_001031888.1 125623405 4798098 537078..537830 1 NC_009004.1 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-ACP reductase 537830 fabI 4798098 fabI Lactococcus lactis subsp. cremoris MG1363 enoyl-ACP reductase YP_001031888.1 537078 D 416870 CDS YP_001031889.1 125623406 4796589 complement(538093..539055) 1 NC_009004.1 involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site; OxaA-like protein precursor 539055 oxaA2 4796589 oxaA2 Lactococcus lactis subsp. cremoris MG1363 OxaA-like protein precursor YP_001031889.1 538093 R 416870 CDS YP_001031890.1 125623407 4799082 complement(539230..539988) 1 NC_009004.1 HAD-SF-IIB: HAD-superfamily hydrolase, subfamily IIB; High confidence in function and specificity; alpha-phosphoglucomutase 539988 pgmA 4799082 pgmA Lactococcus lactis subsp. cremoris MG1363 alpha-phosphoglucomutase YP_001031890.1 539230 R 416870 CDS YP_001031891.1 125623408 4798394 complement(540083..540673) 1 NC_009004.1 hypothetical protein 540673 4798394 llmg_0542 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031891.1 540083 R 416870 CDS YP_001031892.1 125623409 4798032 complement(540690..541226) 1 NC_009004.1 decarboxylates 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine.; phosphopantothenoylcysteine decarboxylase 541226 dfpA 4798032 dfpA Lactococcus lactis subsp. cremoris MG1363 phosphopantothenoylcysteine decarboxylase YP_001031892.1 540690 R 416870 CDS YP_001031893.1 125623410 4798892 complement(541219..541914) 1 NC_009004.1 (Phosphopantothenoylcysteine synthetase) (PPC synthetase); High confidence in function and specificity; phosphopantothenate--cysteine ligase 541914 dfpB 4798892 dfpB Lactococcus lactis subsp. cremoris MG1363 phosphopantothenate--cysteine ligase YP_001031893.1 541219 R 416870 CDS YP_001031894.1 125623411 4798895 complement(542061..542246) 1 NC_009004.1 4-oxalocrotonate tautomerase 542246 xylH 4798895 xylH Lactococcus lactis subsp. cremoris MG1363 4-oxalocrotonate tautomerase YP_001031894.1 542061 R 416870 CDS YP_001031895.1 125623412 4798021 542442..544769 1 NC_009004.1 ATPase-IIIA_H: plasma-membrane proton-efflux P-type ATPase; High confidence in function and specificity; cation transporter E1-E2 family ATPase 544769 ctpE 4798021 ctpE Lactococcus lactis subsp. cremoris MG1363 cation transporter E1-E2 family ATPase YP_001031895.1 542442 D 416870 CDS YP_001031896.1 125623413 4798839 544801..544968 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 544968 4798839 llmg_0548 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031896.1 544801 D 416870 CDS YP_001031897.1 125623414 4797534 complement(545001..545840) 1 NC_009004.1 Integrase core domain; High confidence in function and specificity; transposase for insertion sequence element IS981A 545840 tnp981 4797534 tnp981 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS981A YP_001031897.1 545001 R 416870 CDS YP_001031898.1 125623415 4797337 complement(545852..546112) 1 NC_009004.1 transposase helper protein for IS981; hypothetical protein 546112 4797337 llmg_0550 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031898.1 545852 R 416870 CDS YP_001031899.1 125623416 4797599 546237..546833 1 NC_009004.1 hypothetical protein 546833 4797599 llmg_0551 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031899.1 546237 D 416870 CDS YP_001031900.1 125623417 4797545 546982..547338 1 NC_009004.1 Conserved hypothetical protein; glyoxylase 547338 4797545 llmg_0552 Lactococcus lactis subsp. cremoris MG1363 glyoxylase YP_001031900.1 546982 D 416870 CDS YP_001031901.1 125623418 4797607 547560..547844 1 NC_009004.1 contains a dimeric alpha-beta barrel domain; hypothetical protein 547844 4797607 llmg_0553 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031901.1 547560 D 416870 CDS YP_001031902.1 125623419 4798745 complement(548155..549330) 1 NC_009004.1 High confidence in function and specificity; transposase for insertion sequence element IS905B 549330 tnp905 4798745 tnp905 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS905B YP_001031902.1 548155 R 416870 CDS YP_001031903.1 125623420 4797965 549717..550286 1 NC_009004.1 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 550286 tdk 4797965 tdk Lactococcus lactis subsp. cremoris MG1363 thymidine kinase YP_001031903.1 549717 D 416870 CDS YP_001031904.1 125623421 4798761 550297..550740 1 NC_009004.1 hypothetical protein 550740 4798761 llmg_0556 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031904.1 550297 D 416870 CDS YP_001031905.1 125623422 4798733 550758..551831 1 NC_009004.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 551831 prfA 4798733 prfA Lactococcus lactis subsp. cremoris MG1363 peptide chain release factor 1 YP_001031905.1 550758 D 416870 CDS YP_001031906.1 125623423 4797127 551831..552358 1 NC_009004.1 hypothetical protein 552358 4797127 llmg_0558 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031906.1 551831 D 416870 CDS YP_001031907.1 125623424 4798593 552428..553183 1 NC_009004.1 Nitroreductase; Family membership; NADPH-flavin oxidoreductase 553183 4798593 llmg_0559 Lactococcus lactis subsp. cremoris MG1363 NADPH-flavin oxidoreductase YP_001031907.1 552428 D 416870 CDS YP_001031908.1 125623425 4798586 553288..554100 1 NC_009004.1 Protein-glutamine N- methyltransferase; High confidence in function and specificity; protoporphyrinogen oxidase 554100 hemK 4798586 hemK Lactococcus lactis subsp. cremoris MG1363 protoporphyrinogen oxidase YP_001031908.1 553288 D 416870 CDS YP_001031909.1 125623426 4797562 554134..554598 1 NC_009004.1 GCN5-related N-acetyltransferase, Acetyltransferase (GNAT) family; Family membership; acetyltransferase 554598 4797562 llmg_0561 Lactococcus lactis subsp. cremoris MG1363 acetyltransferase YP_001031909.1 554134 D 416870 CDS YP_001031910.1 125623427 4798061 554595..555515 1 NC_009004.1 TIGR00057: Sua5/YciO/YrdC/YwlC family protein; Family membership; translation factor 555515 4798061 llmg_0562 Lactococcus lactis subsp. cremoris MG1363 translation factor YP_001031910.1 554595 D 416870 CDS YP_001031911.1 125623428 4798116 555748..556995 1 NC_009004.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 556995 glyA 4798116 glyA Lactococcus lactis subsp. cremoris MG1363 serine hydroxymethyltransferase YP_001031911.1 555748 D 416870 CDS YP_001031912.1 125623429 4798729 557176..557778 1 NC_009004.1 Similar to pneumococcal vaccine antigen A; Specificity unclear; soluble lytic murein transglycosylase 557778 4798729 llmg_0564 Lactococcus lactis subsp. cremoris MG1363 soluble lytic murein transglycosylase YP_001031912.1 557176 D 416870 CDS YP_001031913.1 125623430 4797974 557905..559002 1 NC_009004.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 559002 serC 4797974 serC Lactococcus lactis subsp. cremoris MG1363 phosphoserine aminotransferase YP_001031913.1 557905 D 416870 CDS YP_001031914.1 125623431 4796833 558999..560195 1 NC_009004.1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; High confidence in function and specificity; D-3-phosphoglycerate dehydrogenase 560195 serA 4796833 serA Lactococcus lactis subsp. cremoris MG1363 D-3-phosphoglycerate dehydrogenase YP_001031914.1 558999 D 416870 CDS YP_001031915.1 125623432 4797214 560241..560903 1 NC_009004.1 High confidence in function and specificity; SerB protein 560903 serB 4797214 serB Lactococcus lactis subsp. cremoris MG1363 SerB protein YP_001031915.1 560241 D 416870 CDS YP_001031916.1 125623433 4797202 complement(560940..561233) 1 NC_009004.1 catalyzes the hydrolysis of acylphosphate; acylphosphatase 561233 4797202 llmg_0568 Lactococcus lactis subsp. cremoris MG1363 acylphosphatase YP_001031916.1 560940 R 416870 CDS YP_001031917.1 125623434 4797838 561345..562103 1 NC_009004.1 23S rRNA (guanosine-2'-O-)-methyltransferase, rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3; High confidence in function and specificity; rRNA methyltransferase 562103 spoU 4797838 spoU Lactococcus lactis subsp. cremoris MG1363 rRNA methyltransferase YP_001031917.1 561345 D 416870 CDS YP_001031918.1 125623435 4796850 complement(562315..562704) 1 NC_009004.1 contains RmlC-like cupin domain; Family membership; hypothetical protein 562704 4796850 llmg_0571 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031918.1 562315 R 416870 CDS YP_001031919.1 125623436 4796845 563010..563357 1 NC_009004.1 HTH-type transcriptional regulator, DNA binding; Family membership; MerR family transcriptional regulator 563357 4796845 llmg_0572 Lactococcus lactis subsp. cremoris MG1363 MerR family transcriptional regulator YP_001031919.1 563010 D 416870 CDS YP_001031920.1 125623437 4798107 563371..563697 1 NC_009004.1 Similar to inorganic pyrophosphatase; Function unclear; hypothetical protein 563697 4798107 llmg_0573 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031920.1 563371 D 416870 CDS YP_001031921.1 125623438 4797442 complement(563889..564332) 1 NC_009004.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 564332 fld 4797442 fld Lactococcus lactis subsp. cremoris MG1363 flavodoxin YP_001031921.1 563889 R 416870 CDS YP_001031922.1 125623439 4797518 566198..566827 1 NC_009004.1 contains Homeodomain-like domain; Family membership; TetR family transcriptional regulator 566827 4797518 llmg_0576 Lactococcus lactis subsp. cremoris MG1363 TetR family transcriptional regulator YP_001031922.1 566198 D 416870 CDS YP_001031923.1 125623440 4798712 567107..567961 1 NC_009004.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; methionine aminopeptidase 567961 pepM 4798712 pepM Lactococcus lactis subsp. cremoris MG1363 methionine aminopeptidase YP_001031923.1 567107 D 416870 CDS YP_001031924.1 125623441 4798146 567981..568886 1 NC_009004.1 Ribonuclease BN-like family; Function unclear; tRNA-processing ribonuclease BN 568886 4798146 llmg_0578 Lactococcus lactis subsp. cremoris MG1363 tRNA-processing ribonuclease BN YP_001031924.1 567981 D 416870 CDS YP_001031925.1 125623442 4798572 complement(568989..569435) 1 NC_009004.1 GtrA-like protein; Conserved hypothetical protein; hypothetical protein 569435 4798572 llmg_0579 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031925.1 568989 R 416870 CDS YP_001031926.1 125623443 4798704 569967..570143 1 NC_009004.1 hypothetical protein 570143 4798704 llmg_0581 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031926.1 569967 D 416870 CDS YP_001031927.1 125623444 4798577 570276..571208 1 NC_009004.1 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase 571208 ptsK 4798577 ptsK Lactococcus lactis subsp. cremoris MG1363 HPr kinase/phosphorylase YP_001031927.1 570276 D 416870 CDS YP_001031928.1 125623445 4797708 571270..572055 1 NC_009004.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 572055 lgt 4797708 lgt Lactococcus lactis subsp. cremoris MG1363 prolipoprotein diacylglyceryl transferase YP_001031928.1 571270 D 416870 CDS YP_001031929.1 125623446 4797638 572222..572641 1 NC_009004.1 Bacterial protein of unknown function DUF948, general stress protein; hypothetical protein 572641 4797638 llmg_0584 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031929.1 572222 D 416870 CDS YP_001031930.1 125623447 4798569 572671..573231 1 NC_009004.1 hypothetical protein 573231 4798569 llmg_0585 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031930.1 572671 D 416870 CDS YP_001031931.1 125623448 4798708 573365..574783 1 NC_009004.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 574783 gnd 4798708 gnd Lactococcus lactis subsp. cremoris MG1363 6-phosphogluconate dehydrogenase YP_001031931.1 573365 D 416870 CDS YP_001031932.1 125623449 4796720 577201..579216 1 NC_009004.1 K+ potassium transporter; Conserved hypothetical protein; potassium transport system protein kupB 579216 kupB 4796720 kupB Lactococcus lactis subsp. cremoris MG1363 potassium transport system protein kupB YP_001031932.1 577201 D 416870 CDS YP_001031933.1 125623450 4797612 complement(579269..579439) 1 NC_009004.1 hypothetical protein 579439 4797612 llmg_0589 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031933.1 579269 R 416870 CDS YP_001031934.1 125623451 4798012 579634..580299 1 NC_009004.1 Protein of unknown function DUF161, Uncharacterized BCR, YitT family COG1284; Conserved hypothetical protein; hypothetical protein 580299 4798012 llmg_0590 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031934.1 579634 D 416870 CDS YP_001031935.1 125623452 4796811 580430..581314 1 NC_009004.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 581314 miaA 4796811 miaA Lactococcus lactis subsp. cremoris MG1363 tRNA delta(2)-isopentenylpyrophosphate transferase YP_001031935.1 580430 D 416870 CDS YP_001031936.1 125623453 4798070 581460..582128 1 NC_009004.1 Function unclear; hypothetical protein 582128 4798070 llmg_0592 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031936.1 581460 D 416870 CDS YP_001031937.1 125623454 4798478 582293..583195 1 NC_009004.1 SPFH domain / Band 7 family, Similar to several eukaryotic hypersensitive-induced response proteins; Family membership; prohibitin/stomatin like protein 583195 4798478 llmg_0593 Lactococcus lactis subsp. cremoris MG1363 prohibitin/stomatin like protein YP_001031937.1 582293 D 416870 CDS YP_001031938.1 125623455 4797418 complement(583444..584460) 1 NC_009004.1 DNA breaking-rejoining enzyme, catalytic core, site- specific recombinase, phage integrase; High confidence in function and specificity; phage integrase 584460 ps201 4797418 ps201 Lactococcus lactis subsp. cremoris MG1363 phage integrase YP_001031938.1 583444 R 416870 CDS YP_001031939.1 125623456 4798011 complement(584681..585172) 1 NC_009004.1 Similar to ps202 from IL1403, phage associated; hypothetical protein 585172 ps202 4798011 ps202 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031939.1 584681 R 416870 CDS YP_001031940.1 125623457 4798434 complement(585448..585657) 1 NC_009004.1 hypothetical protein 585657 ps203 4798434 ps203 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031940.1 585448 R 416870 CDS YP_001031941.1 125623458 4797908 complement(585725..585976) 1 NC_009004.1 Similar to pi358 from IL1403, Phage associated; hypothetical protein 585976 ps204 4797908 ps204 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031941.1 585725 R 416870 CDS YP_001031942.1 125623459 4798045 complement(586213..586395) 1 NC_009004.1 phage associated; cI-like repressor 586395 ps205 4798045 ps205 Lactococcus lactis subsp. cremoris MG1363 cI-like repressor YP_001031942.1 586213 R 416870 CDS YP_001031943.1 125623460 4797818 586683..588290 1 NC_009004.1 Region start changed from 586756 to 586684 (72 bases); hypothetical protein 588290 4797818 llmg_0599 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031943.1 586683 D 416870 CDS YP_001031944.1 125623461 4798487 588208..589146 1 NC_009004.1 Glycosyl transferase, family 2; High confidence in function and specificity; glycosyl transferase family protein 589146 4798487 llmg_0600 Lactococcus lactis subsp. cremoris MG1363 glycosyl transferase family protein YP_001031944.1 588208 D 416870 CDS YP_001031945.1 125623462 4798082 complement(589412..589903) 1 NC_009004.1 hypothetical protein 589903 4798082 llmg_0601 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031945.1 589412 R 416870 CDS YP_001031946.1 125623463 4797623 complement(589916..590290) 1 NC_009004.1 Disruption induces osmosensitive phenotype; hypothetical protein 590290 4797623 llmg_0602 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031946.1 589916 R 416870 CDS YP_001031947.1 125623464 4797614 complement(590635..590982) 1 NC_009004.1 Similar to Lactococcus bacteriophage repressor; Function unclear; HTH-type transcriptional regulator 590982 4797614 llmg_0603 Lactococcus lactis subsp. cremoris MG1363 HTH-type transcriptional regulator YP_001031947.1 590635 R 416870 CDS YP_001031948.1 125623465 4796990 591748..592671 1 NC_009004.1 member of metallo-beta-lactamase; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 592671 4796990 llmg_0604 Lactococcus lactis subsp. cremoris MG1363 ribonuclease Z YP_001031948.1 591748 D 416870 CDS YP_001031949.1 125623466 4798003 592616..593365 1 NC_009004.1 Oxidoreductase, Short-chain dehydrogenase; Family membership; oxidoreductase 593365 4798003 llmg_0605 Lactococcus lactis subsp. cremoris MG1363 oxidoreductase YP_001031949.1 592616 D 416870 CDS YP_001031950.1 125623467 4799023 593538..595766 1 NC_009004.1 DHH family; High confidence in function and specificity; ssDNA-binding protein 595766 recJ 4799023 recJ Lactococcus lactis subsp. cremoris MG1363 ssDNA-binding protein YP_001031950.1 593538 D 416870 CDS YP_001031951.1 125623468 4796716 595890..596402 1 NC_009004.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 596402 apt 4796716 apt Lactococcus lactis subsp. cremoris MG1363 adenine phosphoribosyltransferase YP_001031951.1 595890 D 416870 CDS YP_001031952.1 125623469 4798525 596618..597184 1 NC_009004.1 participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; DNA-directed RNA polymerase subunit delta 597184 rpoE 4798525 rpoE Lactococcus lactis subsp. cremoris MG1363 DNA-directed RNA polymerase subunit delta YP_001031952.1 596618 D 416870 CDS YP_001031953.1 125623470 4797538 597323..598960 1 NC_009004.1 TIGR00247: conserved hypothetical protein TIGR00247; aminodeoxychorismate lyase 598960 pabC 4797538 pabC Lactococcus lactis subsp. cremoris MG1363 aminodeoxychorismate lyase YP_001031953.1 597323 D 416870 CDS YP_001031954.1 125623471 4799077 599021..599491 1 NC_009004.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 599491 greA 4799077 greA Lactococcus lactis subsp. cremoris MG1363 transcription elongation factor GreA YP_001031954.1 599021 D 416870 CDS YP_001031955.1 125623472 4798731 599583..600140 1 NC_009004.1 Family membership; hypothetical protein 600140 4798731 llmg_0611 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031955.1 599583 D 416870 CDS YP_001031956.1 125623473 4797522 601031..601321 1 NC_009004.1 transposase helper protein for IS904; hypothetical protein 601321 4797522 llmg_0612 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031956.1 601031 D 416870 CDS YP_001031957.1 125623474 4796780 601417..602178 1 NC_009004.1 Region start changed from 601339 to 601417 (-78 bases); transposase for insertion sequence element IS904B 602178 4796780 llmg_0613 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS904B YP_001031957.1 601417 D 416870 CDS YP_001031958.1 125623475 4798658 602409..602864 1 NC_009004.1 Firmicute transcriptional repressor of class III stress genes; High confidence in function and specificity; transcriptional regulator ctsR 602864 ctsR 4798658 ctsR Lactococcus lactis subsp. cremoris MG1363 transcriptional regulator ctsR YP_001031958.1 602409 D 416870 CDS YP_001031959.1 125623476 4798843 602854..605304 1 NC_009004.1 High confidence in function and specificity; ATP-dependent Clp protease ATP-binding subunit 605304 clpC 4798843 clpC Lactococcus lactis subsp. cremoris MG1363 ATP-dependent Clp protease ATP-binding subunit YP_001031959.1 602854 D 416870 CDS YP_001031960.1 125623477 4797022 605439..605996 1 NC_009004.1 Sigma 54 modulation protein/ribosomal protein S30EA, Similar to yfiA in E. Coli, ribosomal subunit interface protein; Specificity unclear; sigma 54 modulation protein 605996 yfiA 4797022 yfiA Lactococcus lactis subsp. cremoris MG1363 sigma 54 modulation protein YP_001031960.1 605439 D 416870 CDS YP_001031961.1 125623478 4797432 606184..607485 1 NC_009004.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 607485 eno 4797432 eno Lactococcus lactis subsp. cremoris MG1363 phosphopyruvate hydratase YP_001031961.1 606184 D 416870 CDS YP_001031962.1 125623479 4796855 607574..608509 1 NC_009004.1 DNA breaking-rejoining enzyme, catalytic core, Phage integrase; Conserved hypothetical protein; integrase-recombinase 608509 xerD 4796855 xerD Lactococcus lactis subsp. cremoris MG1363 integrase-recombinase YP_001031962.1 607574 D 416870 CDS YP_001031963.1 125623480 4797946 608636..609268 1 NC_009004.1 Also present on plasmid pJW394; Conserved hypothetical protein; hypothetical protein 609268 4797946 llmg_0619 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031963.1 608636 D 416870 CDS YP_001031964.1 125623481 4797894 complement(610648..611487) 1 NC_009004.1 Integrase, catalytic region; High confidence in function and specificity; transposase for insertion sequence element IS981B 611487 tnp981 4797894 tnp981 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS981B YP_001031964.1 610648 R 416870 CDS YP_001031965.1 125623482 4797338 complement(611499..611759) 1 NC_009004.1 transposase helper protein for IS981; hypothetical protein 611759 4797338 llmg_0622 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031965.1 611499 R 416870 CDS YP_001031966.1 125623483 4796759 611839..612519 1 NC_009004.1 High confidence in function and specificity; abortive phage resistance protein abiP 612519 abiP 4796759 abiP Lactococcus lactis subsp. cremoris MG1363 abortive phage resistance protein abiP YP_001031966.1 611839 D 416870 CDS YP_001031967.1 125623484 4797502 complement(613053..613724) 1 NC_009004.1 Specificity unclear; ABC transporter ATP-binding protein 613724 4797502 llmg_0624 Lactococcus lactis subsp. cremoris MG1363 ABC transporter ATP-binding protein YP_001031967.1 613053 R 416870 CDS YP_001031968.1 125623485 4798809 complement(613726..614799) 1 NC_009004.1 Protein of unknown function DUF214; Conserved hypothetical protein; ABC transporter permease 614799 4798809 llmg_0625 Lactococcus lactis subsp. cremoris MG1363 ABC transporter permease YP_001031968.1 613726 R 416870 CDS YP_001031969.1 125623486 4796859 complement(614811..615380) 1 NC_009004.1 Homeodomain-like; transcriptional regulator 615380 4796859 llmg_0626 Lactococcus lactis subsp. cremoris MG1363 transcriptional regulator YP_001031969.1 614811 R 416870 CDS YP_001031970.1 125623487 4797698 complement(615570..617093) 1 NC_009004.1 Acetyl-coenzyme A synthetase; High confidence in function and specificity; long-chain acyl-CoA synthetase 617093 fadD 4797698 fadD Lactococcus lactis subsp. cremoris MG1363 long-chain acyl-CoA synthetase YP_001031970.1 615570 R 416870 CDS YP_001031971.1 125623488 4796691 617287..618204 1 NC_009004.1 Similar to Mg2+ transporter protein, CorA-like; Specificity unclear; divalent cation transport-related protein 618204 4796691 llmg_0628 Lactococcus lactis subsp. cremoris MG1363 divalent cation transport-related protein YP_001031971.1 617287 D 416870 CDS YP_001031972.1 125623489 4797717 618464..620827 1 NC_009004.1 Pyruvate formate-lyase; High confidence in function and specificity; formate acetyltransferase 620827 pfl 4797717 pfl Lactococcus lactis subsp. cremoris MG1363 formate acetyltransferase YP_001031972.1 618464 D 416870 CDS YP_001031973.1 125623490 4798580 620956..621615 1 NC_009004.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 621615 coaE 4798580 coaE Lactococcus lactis subsp. cremoris MG1363 dephospho-CoA kinase YP_001031973.1 620956 D 416870 CDS YP_001031974.1 125623491 4797832 621618..622835 1 NC_009004.1 Major Facilitator Superfamily; High confidence in function and specificity; multidrug resistance efflux pump 622835 pmrA 4797832 pmrA Lactococcus lactis subsp. cremoris MG1363 multidrug resistance efflux pump YP_001031974.1 621618 D 416870 CDS YP_001031975.1 125623492 4797829 622832..622978 1 NC_009004.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 622978 rpmG 4797829 rpmG Lactococcus lactis subsp. cremoris MG1363 50S ribosomal protein L33 YP_001031975.1 622832 D 416870 CDS YP_001031976.1 125623493 4798811 623355..624617 1 NC_009004.1 rodA_shape: rod shape-determining protein RodA; High confidence in function and specificity; cell division protein FtsW 624617 ftsW1 4798811 ftsW1 Lactococcus lactis subsp. cremoris MG1363 cell division protein FtsW YP_001031976.1 623355 D 416870 CDS YP_001031977.1 125623494 4798789 624722..628135 1 NC_009004.1 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate; pyruvate carboxylase 628135 pycA 4798789 pycA Lactococcus lactis subsp. cremoris MG1363 pyruvate carboxylase YP_001031977.1 624722 D 416870 CDS YP_001031978.1 125623495 4797704 628261..629586 1 NC_009004.1 catalyzes the formation of citrate from acetyl-CoA and oxaloacetate; citrate synthase 629586 gltA 4797704 gltA Lactococcus lactis subsp. cremoris MG1363 citrate synthase YP_001031978.1 628261 D 416870 CDS YP_001031979.1 125623496 4798330 629583..632129 1 NC_009004.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 632129 citB 4798330 citB Lactococcus lactis subsp. cremoris MG1363 aconitate hydratase YP_001031979.1 629583 D 416870 CDS YP_001031980.1 125623497 4796910 632149..633387 1 NC_009004.1 High confidence in function and specificity; isocitrate dehydrogenase 633387 icd 4796910 icd Lactococcus lactis subsp. cremoris MG1363 isocitrate dehydrogenase YP_001031980.1 632149 D 416870 CDS YP_001031981.1 125623498 4796752 complement(633447..634046) 1 NC_009004.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 634046 clpP 4796752 clpP Lactococcus lactis subsp. cremoris MG1363 ATP-dependent Clp protease proteolytic subunit YP_001031981.1 633447 R 416870 CDS YP_001031982.1 125623499 4796569 634242..634772 1 NC_009004.1 hypothetical protein 634772 4796569 llmg_0639 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031982.1 634242 D 416870 CDS YP_001031983.1 125623500 4798366 634943..635341 1 NC_009004.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; transcriptional regulator Spx 635341 spxA 4798366 spxA Lactococcus lactis subsp. cremoris MG1363 transcriptional regulator Spx YP_001031983.1 634943 D 416870 CDS YP_001031984.1 125623501 4798059 complement(635494..635628) 1 NC_009004.1 hypothetical protein 635628 4798059 llmg_0641 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031984.1 635494 R 416870 CDS YP_001031985.1 125623502 4798392 complement(635725..636888) 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 636888 4798392 llmg_0642 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031985.1 635725 R 416870 CDS YP_001031986.1 125623503 4798401 637215..639971 1 NC_009004.1 Specificity unclear; cation transporter E1-E2 family ATPase 639971 pacL 4798401 pacL Lactococcus lactis subsp. cremoris MG1363 cation transporter E1-E2 family ATPase YP_001031986.1 637215 D 416870 CDS YP_001031987.1 125623504 4799075 640489..640968 1 NC_009004.1 hypothetical protein 640968 4799075 llmg_0644 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031987.1 640489 D 416870 CDS YP_001031988.1 125623505 4796782 640986..641516 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 641516 4796782 llmg_0645 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031988.1 640986 D 416870 CDS YP_001031989.1 125623506 4797189 641521..642735 1 NC_009004.1 Glycosyl transferase, family 2; Function unclear; intercellular adhesion protein A 642735 icaA 4797189 icaA Lactococcus lactis subsp. cremoris MG1363 intercellular adhesion protein A YP_001031989.1 641521 D 416870 CDS YP_001031990.1 125623507 4797663 complement(643149..643988) 1 NC_009004.1 Integrase, catalytic region; High confidence in function and specificity; transposase for insertion sequence element IS981C 643988 tnp981 4797663 tnp981 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS981C YP_001031990.1 643149 R 416870 CDS YP_001031991.1 125623508 4797332 complement(644000..644260) 1 NC_009004.1 transposase helper protein for IS981; Family membership; hypothetical protein 644260 4797332 llmg_0648 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031991.1 644000 R 416870 CDS YP_001031992.1 125623509 4796779 644291..645115 1 NC_009004.1 Similar to polysaccharide deacetylase; High confidence in function and specificity; intercellular adhesion protein B 645115 icaB 4796779 icaB Lactococcus lactis subsp. cremoris MG1363 intercellular adhesion protein B YP_001031992.1 644291 D 416870 CDS YP_001031993.1 125623510 4797732 complement(645202..646551) 1 NC_009004.1 branched-chain amino acid:cation transporter LIVCS family; High confidence in function and specificity; branched chain amino acid ABC transporter carrier protein 646551 brnQ 4797732 brnQ Lactococcus lactis subsp. cremoris MG1363 branched chain amino acid ABC transporter carrier protein YP_001031993.1 645202 R 416870 CDS YP_001031994.1 125623511 4797683 complement(646767..647039) 1 NC_009004.1 Conserved hypothetical protein; acetyltransferase 647039 4797683 llmg_0651 Lactococcus lactis subsp. cremoris MG1363 acetyltransferase YP_001031994.1 646767 R 416870 CDS YP_001031995.1 125623512 4797427 complement(647207..647968) 1 NC_009004.1 Region start changed from 648046 to 647968 (-78 bases); transposase for insertion sequence element IS904C 647968 4797427 llmg_0652 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS904C YP_001031995.1 647207 R 416870 CDS YP_001031996.1 125623513 4796713 complement(648202..648354) 1 NC_009004.1 transposase helper protein for insertion sequence element IS904; hypothetical protein 648354 4796713 llmg_0653 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001031996.1 648202 R 416870 CDS YP_001031997.1 125623514 4797568 complement(648490..649110) 1 NC_009004.1 Integrase, catalytic region; High confidence in function and specificity; transposase for insertion sequence element IS-LL6B 649110 4797568 llmg_0654 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS-LL6B YP_001031997.1 648490 R 416870 CDS YP_001031998.1 125623515 4797897 complement(649272..649547) 1 NC_009004.1 contains Homeodomain-like region; Family membership; transposase 649547 4797897 llmg_0655 Lactococcus lactis subsp. cremoris MG1363 transposase YP_001031998.1 649272 R 416870 CDS YP_001031999.1 125623516 4797879 complement(649642..650532) 1 NC_009004.1 Transposase DDE domain; Family membership; transposase for insertion sequence element IS982B 650532 tnp982 4797879 tnp982 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS982B YP_001031999.1 649642 R 416870 CDS YP_001032000.1 125623517 4797901 650883..654059 1 NC_009004.1 Specificity unclear; type I restriction-modification system restriction subunit 654059 hsdR 4797901 hsdR Lactococcus lactis subsp. cremoris MG1363 type I restriction-modification system restriction subunit YP_001032000.1 650883 D 416870 CDS YP_001032001.1 125623518 4796743 654041..655678 1 NC_009004.1 Type I restriction modification system, M subunit; Specificity unclear; type I site-specific deoxyribonuclease 655678 hsdM 4796743 hsdM Lactococcus lactis subsp. cremoris MG1363 type I site-specific deoxyribonuclease YP_001032001.1 654041 D 416870 CDS YP_001032002.1 125623519 4796694 655644..656894 1 NC_009004.1 Type I restriction modification DNA specificity subunit; Specificity unclear; specificity determinant HsdS 656894 hsdS 4796694 hsdS Lactococcus lactis subsp. cremoris MG1363 specificity determinant HsdS YP_001032002.1 655644 D 416870 CDS YP_001032003.1 125623520 4797705 657080..658030 1 NC_009004.1 Mg2+ transporter protein, CorA-like; Specificity unclear; CorA like magnesium and cobalt transport protein 658030 4797705 llmg_0661 Lactococcus lactis subsp. cremoris MG1363 CorA like magnesium and cobalt transport protein YP_001032003.1 657080 D 416870 CDS YP_001032004.1 125623521 4797823 659931..660578 1 NC_009004.1 catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline; pyrrolidone-carboxylate peptidase 660578 pcp 4797823 pcp Lactococcus lactis subsp. cremoris MG1363 pyrrolidone-carboxylate peptidase YP_001032004.1 659931 D 416870 CDS YP_001032005.1 125623522 4798142 complement(660769..661965) 1 NC_009004.1 Peptidase M20/M25/M40; High confidence in function and specificity; amidase 661965 amd 4798142 amd Lactococcus lactis subsp. cremoris MG1363 amidase YP_001032005.1 660769 R 416870 CDS YP_001032006.1 125623523 4797896 663030..664286 1 NC_009004.1 Major facilitator superfamily; High confidence in function and specificity; oxalate/formate antiporter 664286 oxlT 4797896 oxlT Lactococcus lactis subsp. cremoris MG1363 oxalate/formate antiporter YP_001032006.1 663030 D 416870 CDS YP_001032007.1 125623524 4799081 665114..665431 1 NC_009004.1 GCN5-related N-acetyltransferase; Family membership; hypothetical protein 665431 4799081 llmg_0668 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032007.1 665114 D 416870 CDS YP_001032008.1 125623525 4797920 complement(665705..665857) 1 NC_009004.1 hypothetical protein 665857 4797920 llmg_0669 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032008.1 665705 R 416870 CDS YP_001032009.1 125623526 4797943 complement(665908..666210) 1 NC_009004.1 hypothetical protein 666210 4797943 llmg_0670 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032009.1 665908 R 416870 CDS YP_001032010.1 125623527 4797259 complement(666207..666383) 1 NC_009004.1 TIGR01847: Bacteriocin-type signal sequence; hypothetical protein 666383 4797259 llmg_0671 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032010.1 666207 R 416870 CDS YP_001032011.1 125623528 4796657 666858..666959 1 NC_009004.1 hypothetical protein 666959 4796657 llmg_0672 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032011.1 666858 D 416870 CDS YP_001032012.1 125623529 4797317 complement(666946..667563) 1 NC_009004.1 hypothetical protein 667563 4797317 llmg_0673 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032012.1 666946 R 416870 CDS YP_001032013.1 125623530 4798249 complement(667840..668520) 1 NC_009004.1 High confidence in function and specificity; transposase for insertion sequence element IS1297 668520 tnp1297 4798249 tnp1297 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS1297 YP_001032013.1 667840 R 416870 CDS YP_001032014.1 125623531 4797082 668849..669088 1 NC_009004.1 hypothetical protein 669088 4797082 llmg_0675 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032014.1 668849 D 416870 CDS YP_001032015.1 125623532 4798519 complement(669248..669745) 1 NC_009004.1 GCN5-related N-acetyltransferase, Acetyltransferase (GNAT) family; Family membership; acetyltransferase 669745 4798519 llmg_0676 Lactococcus lactis subsp. cremoris MG1363 acetyltransferase YP_001032015.1 669248 R 416870 CDS YP_001032016.1 125623533 4797937 670033..670245 1 NC_009004.1 hypothetical protein 670245 4797937 llmg_0677 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032016.1 670033 D 416870 CDS YP_001032017.1 125623534 4797483 complement(671109..671369) 1 NC_009004.1 transposase helper protein for IS981 671369 4797483 llmg_0678 Lactococcus lactis subsp. cremoris MG1363 transposase helper protein for IS981 YP_001032017.1 671109 R 416870 CDS YP_001032018.1 125623535 4796888 671499..671690 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 671690 4796888 llmg_0679 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032018.1 671499 D 416870 CDS YP_001032019.1 125623536 4796919 671742..671918 1 NC_009004.1 hypothetical protein 671918 4796919 llmg_0680 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032019.1 671742 D 416870 CDS YP_001032020.1 125623537 4796981 672065..672550 1 NC_009004.1 Lambda repressor-like, DNA-binding., Contains Helix- turn-helix domain; hypothetical protein 672550 4796981 llmg_0681 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032020.1 672065 D 416870 CDS YP_001032021.1 125623538 4798226 672799..674022 1 NC_009004.1 Integrase, catalytic region; Specificity unclear; transposase for insertion sequence element IS712B 674022 tnp712 4798226 tnp712 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS712B YP_001032021.1 672799 D 416870 CDS YP_001032022.1 125623539 4798223 674034..674792 1 NC_009004.1 PF01695: IstB-like ATP-binding protein; Function unclear; transposase helper protein for IS712B 674792 4798223 llmg_0683 Lactococcus lactis subsp. cremoris MG1363 transposase helper protein for IS712B YP_001032022.1 674034 D 416870 CDS YP_001032023.1 125623540 4797462 675028..675867 1 NC_009004.1 Integrase, catalytic region; High confidence in function and specificity; transposase for insertion sequence element IS981E 675867 tnp981 4797462 tnp981 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS981E YP_001032023.1 675028 D 416870 CDS YP_001032024.1 125623541 4797321 676555..676701 1 NC_009004.1 hypothetical protein 676701 4797321 llmg_0685 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032024.1 676555 D 416870 CDS YP_001032025.1 125623542 4797028 677108..677389 1 NC_009004.1 hypothetical protein 677389 4797028 llmg_0686 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032025.1 677108 D 416870 CDS YP_001032026.1 125623543 4796952 677973..678140 1 NC_009004.1 Contains bacteriocin-type signal sequence; hypothetical protein 678140 4796952 llmg_0687 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032026.1 677973 D 416870 CDS YP_001032027.1 125623544 4796732 678147..678449 1 NC_009004.1 hypothetical protein 678449 4796732 llmg_0688 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032027.1 678147 D 416870 CDS YP_001032028.1 125623545 4796991 678500..678628 1 NC_009004.1 hypothetical protein 678628 4796991 llmg_0689 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032028.1 678500 D 416870 CDS YP_001032029.1 125623546 4796688 678701..680563 1 NC_009004.1 E1-E2 ATPase; High confidence in function and specificity; heavy metal-translocating P-type ATPase 680563 4796688 llmg_0690 Lactococcus lactis subsp. cremoris MG1363 heavy metal-translocating P-type ATPase YP_001032029.1 678701 D 416870 CDS YP_001032030.1 125623547 4797070 680949..681047 1 NC_009004.1 hypothetical protein 681047 4797070 llmg_0691 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032030.1 680949 D 416870 CDS YP_001032031.1 125623548 4797091 681269..681496 1 NC_009004.1 Contains Heavy-Metal-Associated (HMA) domain; Specificity unclear; hypothetical protein 681496 4797091 llmg_0692 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032031.1 681269 D 416870 CDS YP_001032032.1 125623549 4796794 681542..682090 1 NC_009004.1 Ferritin/ribonucleotide reductase-like; stress induced DNA binding protein 682090 4796794 llmg_0693 Lactococcus lactis subsp. cremoris MG1363 stress induced DNA binding protein YP_001032032.1 681542 D 416870 CDS YP_001032033.1 125623550 4797002 682176..682865 1 NC_009004.1 Cyclic nucleotide-binding domain; Conserved hypothetical protein; transcriptional regulator FNR like protein B 682865 flpB 4797002 flpB Lactococcus lactis subsp. cremoris MG1363 transcriptional regulator FNR like protein B YP_001032033.1 682176 D 416870 CDS YP_001032034.1 125623551 4798137 683191..683319 1 NC_009004.1 hypothetical protein 683319 4798137 llmg_0695 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032034.1 683191 D 416870 CDS YP_001032035.1 125623552 4798022 complement(683306..683479) 1 NC_009004.1 hypothetical protein 683479 4798022 llmg_0696 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032035.1 683306 R 416870 CDS YP_001032036.1 125623553 4797010 683542..684558 1 NC_009004.1 High confidence in function and specificity; oligopeptide transport ATP-binding protein oppD 684558 oppD 4797010 oppD Lactococcus lactis subsp. cremoris MG1363 oligopeptide transport ATP-binding protein oppD YP_001032036.1 683542 D 416870 CDS YP_001032037.1 125623554 4799087 684555..685514 1 NC_009004.1 High confidence in function and specificity; oligopeptide transport ATP-binding protein oppF 685514 oppF 4799087 oppF Lactococcus lactis subsp. cremoris MG1363 oligopeptide transport ATP-binding protein oppF YP_001032037.1 684555 D 416870 CDS YP_001032038.1 125623555 4799085 685495..686454 1 NC_009004.1 Binding-protein-dependent transport systems inner membrane component; High confidence in function and specificity; peptide transport system permease oppB 686454 oppB 4799085 oppB Lactococcus lactis subsp. cremoris MG1363 peptide transport system permease oppB YP_001032038.1 685495 D 416870 CDS YP_001032039.1 125623556 4799091 686464..687348 1 NC_009004.1 Binding-protein-dependent transport systems inner membrane component; High confidence in function and specificity; oligopeptide transport system permease oppC 687348 oppC 4799091 oppC Lactococcus lactis subsp. cremoris MG1363 oligopeptide transport system permease oppC YP_001032039.1 686464 D 416870 CDS YP_001032040.1 125623557 4799089 687458..689260 1 NC_009004.1 Bacterial extracellular solute-binding protein, family 5; High confidence in function and specificity; oligopeptide-binding protein oppA 689260 oppA 4799089 oppA Lactococcus lactis subsp. cremoris MG1363 oligopeptide-binding protein oppA YP_001032040.1 687458 D 416870 CDS YP_001032041.1 125623558 4799093 689385..691268 1 NC_009004.1 Peptidase M13; High confidence in function and specificity; endopeptidase O 691268 pepO 4799093 pepO Lactococcus lactis subsp. cremoris MG1363 endopeptidase O YP_001032041.1 689385 D 416870 CDS YP_001032042.1 125623559 4798134 691571..692890 1 NC_009004.1 Transposase DDE domain; Specificity unclear; transposase 692890 tnp1675 4798134 tnp1675 Lactococcus lactis subsp. cremoris MG1363 transposase YP_001032042.1 691571 D 416870 CDS YP_001032043.1 125623560 4798344 693318..693521 1 NC_009004.1 hypothetical protein 693521 4798344 llmg_0704 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032043.1 693318 D 416870 CDS YP_001032044.1 125623561 4796758 693514..693837 1 NC_009004.1 hypothetical protein 693837 4796758 llmg_0705 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032044.1 693514 D 416870 CDS YP_001032045.1 125623562 4798195 694246..694527 1 NC_009004.1 hypothetical protein 694527 4798195 llmg_0706 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032045.1 694246 D 416870 CDS YP_001032046.1 125623563 4796810 complement(694698..695015) 1 NC_009004.1 hypothetical protein 695015 4796810 llmg_0707 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032046.1 694698 R 416870 CDS YP_001032047.1 125623564 4796754 complement(694993..695268) 1 NC_009004.1 hypothetical protein 695268 4796754 llmg_0708 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032047.1 694993 R 416870 CDS YP_001032048.1 125623565 4799011 695498..695842 1 NC_009004.1 Family membership; PadR-like family transcriptional regulator 695842 4799011 llmg_0709 Lactococcus lactis subsp. cremoris MG1363 PadR-like family transcriptional regulator YP_001032048.1 695498 D 416870 CDS YP_001032049.1 125623566 4797880 695839..696666 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 696666 4797880 llmg_0710 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032049.1 695839 D 416870 CDS YP_001032050.1 125623567 4796634 696901..697455 1 NC_009004.1 High confidence in function and specificity; DNA-invertase/resolvase 697455 tnpR 4796634 tnpR Lactococcus lactis subsp. cremoris MG1363 DNA-invertase/resolvase YP_001032050.1 696901 D 416870 CDS YP_001032051.1 125623568 4798020 complement(697799..698404) 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 698404 4798020 llmg_0712 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032051.1 697799 R 416870 CDS YP_001032052.1 125623569 4798087 complement(698417..698596) 1 NC_009004.1 hypothetical protein 698596 4798087 llmg_0713 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032052.1 698417 R 416870 CDS YP_001032053.1 125623570 4796938 complement(698693..699532) 1 NC_009004.1 Integrase, catalytic region; High confidence in function and specificity; transposase for insertion sequence element IS981F 699532 tnp981 4796938 tnp981 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS981F YP_001032053.1 698693 R 416870 CDS YP_001032054.1 125623571 4797422 699794..700417 1 NC_009004.1 hypothetical protein 700417 4797422 llmg_0715 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032054.1 699794 D 416870 CDS YP_001032055.1 125623572 4797133 700636..700923 1 NC_009004.1 hypothetical protein 700923 4797133 llmg_0716 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032055.1 700636 D 416870 CDS YP_001032056.1 125623573 4798041 complement(701028..701708) 1 NC_009004.1 Integrase, catalytic region, also known as iso- ISS1; High confidence in function and specificity; transposase for insertion sequence element IS946 701708 tnp946 4798041 tnp946 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS946 YP_001032056.1 701028 R 416870 CDS YP_001032057.1 125623574 4797843 702975..703628 1 NC_009004.1 Similar to molybdenum cofactor biosynthesis protein; Conserved hypothetical protein; nucleotide binding protein 703628 4797843 llmg_0718 Lactococcus lactis subsp. cremoris MG1363 nucleotide binding protein YP_001032057.1 702975 D 416870 CDS YP_001032058.1 125623575 4796970 703621..704781 1 NC_009004.1 Similar to peptide ABC-type transporters; Function unclear; ABC transporter substrate-binding protein 704781 4796970 llmg_0719 Lactococcus lactis subsp. cremoris MG1363 ABC transporter substrate-binding protein YP_001032058.1 703621 D 416870 CDS YP_001032059.1 125623576 4797786 704818..705078 1 NC_009004.1 transposase helper protein for IS981; hypothetical protein 705078 4797786 llmg_0720 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032059.1 704818 D 416870 CDS YP_001032060.1 125623577 4799112 705090..705929 1 NC_009004.1 Integrase, catalytic region; High confidence in function and specificity; transposase for insertion sequence element IS981G 705929 tnp981 4799112 tnp981 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS981G YP_001032060.1 705090 D 416870 CDS YP_001032061.1 125623578 4797292 complement(706170..707441) 1 NC_009004.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 707441 serS 4797292 serS Lactococcus lactis subsp. cremoris MG1363 seryl-tRNA synthetase YP_001032061.1 706170 R 416870 CDS YP_001032062.1 125623579 4798638 complement(707840..708199) 1 NC_009004.1 Domain of unknown function (DUF956); hypothetical protein 708199 4798638 llmg_0724 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032062.1 707840 R 416870 CDS YP_001032063.1 125623580 4797019 708350..709045 1 NC_009004.1 Protein of unknown function DUF161, Uncharacterized BCR, YitT family COG1284; hypothetical protein 709045 4797019 llmg_0725 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032063.1 708350 D 416870 CDS YP_001032064.1 125623581 4797032 complement(709070..709453) 1 NC_009004.1 Protein of unknown function DUF956; hypothetical protein 709453 4797032 llmg_0726 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032064.1 709070 R 416870 CDS YP_001032065.1 125623582 4796916 complement(709596..710519) 1 NC_009004.1 EIID-AGA: PTS system, mannose/fructose/sorbose family, IID component; High confidence in function and specificity; mannose-specific PTS system component IID 710519 ptnD 4796916 ptnD Lactococcus lactis subsp. cremoris MG1363 mannose-specific PTS system component IID YP_001032065.1 709596 R 416870 CDS YP_001032066.1 125623583 4798015 complement(710538..711350) 1 NC_009004.1 EII-Sor: PTS system, mannose/fructose/sorbose family, IIC component; High confidence in function and specificity; mannose-specific PTS system component IIC 711350 ptnC 4798015 ptnC Lactococcus lactis subsp. cremoris MG1363 mannose-specific PTS system component IIC YP_001032066.1 710538 R 416870 CDS YP_001032067.1 125623584 4798027 complement(711429..712418) 1 NC_009004.1 pts-sorbose: PTS system, mannose/fructose/sorbose family, IIB component; High confidence in function and specificity; PTS system mannose-specific transporter subunit IIAB 712418 ptnAB 4798027 ptnAB Lactococcus lactis subsp. cremoris MG1363 PTS system mannose-specific transporter subunit IIAB YP_001032067.1 711429 R 416870 CDS YP_001032068.1 125623585 4798620 complement(712688..712891) 1 NC_009004.1 3Fe-4S ferredoxin; Conserved hypothetical protein; ferredoxin 712891 fer 4798620 fer Lactococcus lactis subsp. cremoris MG1363 ferredoxin YP_001032068.1 712688 R 416870 CDS YP_001032069.1 125623586 4796875 712938..713450 1 NC_009004.1 Contains one Peptidoglycan-binding LysM domain; hypothetical protein 713450 4796875 llmg_0731 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032069.1 712938 D 416870 CDS YP_001032070.1 125623587 4798164 713570..714232 1 NC_009004.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 714232 cmk 4798164 cmk Lactococcus lactis subsp. cremoris MG1363 cytidylate kinase YP_001032070.1 713570 D 416870 CDS YP_001032071.1 125623588 4797320 714312..715703 1 NC_009004.1 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain; High confidence in function and specificity; cell envelope-related transcriptional attenuator 715703 4797320 llmg_0733 Lactococcus lactis subsp. cremoris MG1363 cell envelope-related transcriptional attenuator YP_001032071.1 714312 D 416870 CDS YP_001032072.1 125623589 4797016 715942..716562 1 NC_009004.1 Isochorismatase, Similar to amidases related to nicotinamidase; Family membership; amidase 716562 4797016 llmg_0734 Lactococcus lactis subsp. cremoris MG1363 amidase YP_001032072.1 715942 D 416870 CDS YP_001032073.1 125623590 4797883 717923..718498 1 NC_009004.1 Similar to predicted metal-dependent membrane protease; Conserved hypothetical protein; hypothetical protein 718498 4797883 llmg_0736 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032073.1 717923 D 416870 CDS YP_001032074.1 125623591 4798664 complement(718629..719495) 1 NC_009004.1 High confidence in function and specificity; maltose ABC transporter permease malG 719495 malG 4798664 malG Lactococcus lactis subsp. cremoris MG1363 maltose ABC transporter permease malG YP_001032074.1 718629 R 416870 CDS YP_001032075.1 125623592 4798442 complement(719501..720883) 1 NC_009004.1 High confidence in function and specificity; maltose transport system permease malF 720883 malF 4798442 malF Lactococcus lactis subsp. cremoris MG1363 maltose transport system permease malF YP_001032075.1 719501 R 416870 CDS YP_001032076.1 125623593 4798313 complement(720962..722191) 1 NC_009004.1 Maltotriose-binding protein precursor (Maltodextrin- binding protein); High confidence in function and specificity; maltose ABC transporter substrate binding protein 722191 malE 4798313 malE Lactococcus lactis subsp. cremoris MG1363 maltose ABC transporter substrate binding protein YP_001032076.1 720962 R 416870 CDS YP_001032077.1 125623594 4798284 722564..724318 1 NC_009004.1 Cyclomaltodextrinase; High confidence in function and specificity; neopullulanase 724318 dexC 4798284 dexC Lactococcus lactis subsp. cremoris MG1363 neopullulanase YP_001032077.1 722564 D 416870 CDS YP_001032078.1 125623595 4798891 724633..726228 1 NC_009004.1 High confidence in function and specificity; oligo-1,6-alpha-glucosidase 726228 dexA 4798891 dexA Lactococcus lactis subsp. cremoris MG1363 oligo-1,6-alpha-glucosidase YP_001032078.1 724633 D 416870 CDS YP_001032079.1 125623596 4798887 726255..726860 1 NC_009004.1 High confidence in function and specificity; maltose O-acetyltransferase 726860 maa 4798887 maa Lactococcus lactis subsp. cremoris MG1363 maltose O-acetyltransferase YP_001032079.1 726255 D 416870 CDS YP_001032080.1 125623597 4796751 726850..728424 1 NC_009004.1 High confidence in function and specificity; alpha-amylase 728424 amyY 4796751 amyY Lactococcus lactis subsp. cremoris MG1363 alpha-amylase YP_001032080.1 726850 D 416870 CDS YP_001032081.1 125623598 4797742 728467..730092 1 NC_009004.1 High confidence in function and specificity; alpha-glucosidase 730092 agl 4797742 agl Lactococcus lactis subsp. cremoris MG1363 alpha-glucosidase YP_001032081.1 728467 D 416870 CDS YP_001032082.1 125623599 4797676 730115..732370 1 NC_009004.1 Glycosyl hydrolase 65 central catalytic domain; High confidence in function and specificity; maltose phosphorylase 732370 mapA 4797676 mapA Lactococcus lactis subsp. cremoris MG1363 maltose phosphorylase YP_001032082.1 730115 D 416870 CDS YP_001032083.1 125623600 4798764 732522..733496 1 NC_009004.1 High confidence in function and specificity; maltose operon transcriptional repressor 733496 malR 4798764 malR Lactococcus lactis subsp. cremoris MG1363 maltose operon transcriptional repressor YP_001032083.1 732522 D 416870 CDS YP_001032084.1 125623601 4798749 733674..734342 1 NC_009004.1 Response regulator receiver domain; High confidence in function and specificity; two-component system regulator llrF 734342 llrF 4798749 llrF Lactococcus lactis subsp. cremoris MG1363 two-component system regulator llrF YP_001032084.1 733674 D 416870 CDS YP_001032085.1 125623602 4797659 734558..735928 1 NC_009004.1 Histidine kinase; High confidence in function and specificity; sensor protein kinase kinF 735928 kinF 4797659 kinF Lactococcus lactis subsp. cremoris MG1363 sensor protein kinase kinF YP_001032085.1 734558 D 416870 CDS YP_001032086.1 125623603 4797671 736077..737819 1 NC_009004.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 737819 dxsB 4797671 dxsB Lactococcus lactis subsp. cremoris MG1363 1-deoxy-D-xylulose-5-phosphate synthase YP_001032086.1 736077 D 416870 CDS YP_001032087.1 125623604 4799014 737939..738211 1 NC_009004.1 Protein of unknown function DUF37; hypothetical protein 738211 4799014 llmg_0750 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032087.1 737939 D 416870 CDS YP_001032088.1 125623605 4797097 738330..739763 1 NC_009004.1 required for arbutin uptake and metabolism; 6-phospho-beta-glucosidase 739763 arb 4797097 arb Lactococcus lactis subsp. cremoris MG1363 6-phospho-beta-glucosidase YP_001032088.1 738330 D 416870 CDS YP_001032089.1 125623606 4797230 740024..742729 1 NC_009004.1 High confidence in function and specificity; phage infection protein 742729 pip 4797230 pip Lactococcus lactis subsp. cremoris MG1363 phage infection protein YP_001032089.1 740024 D 416870 CDS YP_001032090.1 125623607 4796576 742828..743568 1 NC_009004.1 High confidence in function and specificity; ubiquinone/menaquinone biosynthesis methyltransferase 743568 ubiE 4796576 ubiE Lactococcus lactis subsp. cremoris MG1363 ubiquinone/menaquinone biosynthesis methyltransferase YP_001032090.1 742828 D 416870 CDS YP_001032091.1 125623608 4797827 743605..744438 1 NC_009004.1 Transcriptional activator, Rgg/GadR/MutR family; Function unclear; Rgg family transcriptional regulator 744438 4797827 llmg_0754 Lactococcus lactis subsp. cremoris MG1363 Rgg family transcriptional regulator YP_001032091.1 743605 D 416870 CDS YP_001032092.1 125623609 4797057 744506..744895 1 NC_009004.1 hypothetical protein 744895 4797057 llmg_0755 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032092.1 744506 D 416870 CDS YP_001032093.1 125623610 4796896 744892..745509 1 NC_009004.1 hypothetical protein 745509 4796896 llmg_0756 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032093.1 744892 D 416870 CDS YP_001032094.1 125623611 4797533 745499..745759 1 NC_009004.1 hypothetical protein 745759 4797533 llmg_0757 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032094.1 745499 D 416870 CDS YP_001032095.1 125623612 4798302 745928..747466 1 NC_009004.1 High confidence in function and specificity; chloride channel protein 747466 eriC 4798302 eriC Lactococcus lactis subsp. cremoris MG1363 chloride channel protein YP_001032095.1 745928 D 416870 CDS YP_001032096.1 125623613 4796765 complement(747491..748450) 1 NC_009004.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 748450 ubiA 4796765 ubiA Lactococcus lactis subsp. cremoris MG1363 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_001032096.1 747491 R 416870 CDS YP_001032097.1 125623614 4798486 749121..749720 1 NC_009004.1 Transglycosylase-like domain; Family membership; transglycosylase 749720 4798486 llmg_0760 Lactococcus lactis subsp. cremoris MG1363 transglycosylase YP_001032097.1 749121 D 416870 CDS YP_001032098.1 125623615 4797459 complement(749986..750966) 1 NC_009004.1 oxidoreductase, Gfo/Idh/MocA family; Family membership; oxidoreductase 750966 4797459 llmg_0761 Lactococcus lactis subsp. cremoris MG1363 oxidoreductase YP_001032098.1 749986 R 416870 CDS YP_001032099.1 125623616 4797841 751263..751883 1 NC_009004.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 751883 udk 4797841 udk Lactococcus lactis subsp. cremoris MG1363 uridine kinase YP_001032099.1 751263 D 416870 CDS YP_001032100.1 125623617 4797970 752099..753079 1 NC_009004.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase 753079 eutD 4797970 eutD Lactococcus lactis subsp. cremoris MG1363 phosphotransacetylase YP_001032100.1 752099 D 416870 CDS YP_001032101.1 125623618 4799041 753217..753609 1 NC_009004.1 hypothetical protein 753609 4799041 llmg_0764 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032101.1 753217 D 416870 CDS YP_001032102.1 125623619 4797909 complement(753649..754434) 1 NC_009004.1 Cof-subfamily: Cof-like hydrolase; Family membership; hydrolase 754434 4797909 llmg_0765 Lactococcus lactis subsp. cremoris MG1363 hydrolase YP_001032102.1 753649 R 416870 CDS YP_001032103.1 125623620 4796834 754626..756893 1 NC_009004.1 FtsK/SpoIIIE family; High confidence in function and specificity; DNA translocase FtsK 756893 ftsK 4796834 ftsK Lactococcus lactis subsp. cremoris MG1363 DNA translocase FtsK YP_001032103.1 754626 D 416870 CDS YP_001032104.1 125623621 4796840 756890..757468 1 NC_009004.1 hypothetical protein 757468 4796840 llmg_0767 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032104.1 756890 D 416870 CDS YP_001032105.1 125623622 4797170 757470..758474 1 NC_009004.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 758474 holA 4797170 holA Lactococcus lactis subsp. cremoris MG1363 DNA polymerase III subunit delta YP_001032105.1 757470 D 416870 CDS YP_001032106.1 125623623 4796763 758531..758917 1 NC_009004.1 Family membership; DivIVA cell division initiation protein 758917 4796763 llmg_0769 Lactococcus lactis subsp. cremoris MG1363 DivIVA cell division initiation protein YP_001032106.1 758531 D 416870 CDS YP_001032107.1 125623624 4798250 759553..760707 1 NC_009004.1 Family membership; N-6 adenine-specific DNA methylase 760707 4798250 llmg_0771 Lactococcus lactis subsp. cremoris MG1363 N-6 adenine-specific DNA methylase YP_001032107.1 759553 D 416870 CDS YP_001032108.1 125623625 4796839 760889..762898 1 NC_009004.1 hypothetical protein 762898 4796839 llmg_0772 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032108.1 760889 D 416870 CDS YP_001032109.1 125623626 4798484 complement(763002..764090) 1 NC_009004.1 Xaa-Pro dipeptidase; High confidence in function and specificity; proline dipeptidase 764090 pepQ 4798484 pepQ Lactococcus lactis subsp. cremoris MG1363 proline dipeptidase YP_001032109.1 763002 R 416870 CDS YP_001032110.1 125623627 4798133 764304..765302 1 NC_009004.1 High confidence in function and specificity; catabolite control protein A 765302 ccpA 4798133 ccpA Lactococcus lactis subsp. cremoris MG1363 catabolite control protein A YP_001032110.1 764304 D 416870 CDS YP_001032111.1 125623628 4798588 765436..766401 1 NC_009004.1 High confidence in function and specificity; TrxB2 protein 766401 trxB2 4798588 trxB2 Lactococcus lactis subsp. cremoris MG1363 TrxB2 protein YP_001032111.1 765436 D 416870 CDS YP_001032112.1 125623629 4798634 766699..767259 1 NC_009004.1 Similar to Colicin V production protein; Conserved hypothetical protein; hypothetical protein 767259 4798634 llmg_0777 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032112.1 766699 D 416870 CDS YP_001032113.1 125623630 4798252 767303..769633 1 NC_009004.1 mutS2: MutS2 family protein; High confidence in function and specificity; DNA mismatch repair protein mutS 769633 mutS 4798252 mutS Lactococcus lactis subsp. cremoris MG1363 DNA mismatch repair protein mutS YP_001032113.1 767303 D 416870 CDS YP_001032114.1 125623631 4798742 769730..770044 1 NC_009004.1 Contains thioredoxin domain 2; High confidence in function and specificity; thioredoxin 770044 trxA 4798742 trxA Lactococcus lactis subsp. cremoris MG1363 thioredoxin YP_001032114.1 769730 D 416870 CDS YP_001032115.1 125623632 4797145 770287..770490 1 NC_009004.1 hypothetical protein 770490 4797145 llmg_0781 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032115.1 770287 D 416870 CDS YP_001032116.1 125623633 4798537 770763..771452 1 NC_009004.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 771452 aroD 4798537 aroD Lactococcus lactis subsp. cremoris MG1363 3-dehydroquinate dehydratase YP_001032116.1 770763 D 416870 CDS YP_001032117.1 125623634 4798929 771667..772962 1 NC_009004.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 772962 purB 4798929 purB Lactococcus lactis subsp. cremoris MG1363 adenylosuccinate lyase YP_001032117.1 771667 D 416870 CDS YP_001032118.1 125623635 4798522 773097..774080 1 NC_009004.1 High confidence in function and specificity; ribose operon repressor 774080 rbsR 4798522 rbsR Lactococcus lactis subsp. cremoris MG1363 ribose operon repressor YP_001032118.1 773097 D 416870 CDS YP_001032119.1 125623636 4796582 774091..775011 1 NC_009004.1 High confidence in function and specificity; ribokinase 775011 rbsK 4796582 rbsK Lactococcus lactis subsp. cremoris MG1363 ribokinase YP_001032119.1 774091 D 416870 CDS YP_001032120.1 125623637 4796656 775016..775414 1 NC_009004.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 775414 rbsD 4796656 rbsD Lactococcus lactis subsp. cremoris MG1363 D-ribose pyranase YP_001032120.1 775016 D 416870 CDS YP_001032121.1 125623638 4796781 775445..776911 1 NC_009004.1 RbsD / FucU transport protein family; High confidence in function and specificity; ribose ABC transporter permease RbsD 776911 rbsD 4796781 rbsD Lactococcus lactis subsp. cremoris MG1363 ribose ABC transporter permease RbsD YP_001032121.1 775445 D 416870 CDS YP_001032122.1 125623639 4796761 776908..777855 1 NC_009004.1 High confidence in function and specificity; ribose transport system permease RbsC 777855 rbsC 4796761 rbsC Lactococcus lactis subsp. cremoris MG1363 ribose transport system permease RbsC YP_001032122.1 776908 D 416870 CDS YP_001032123.1 125623640 4796819 777867..778841 1 NC_009004.1 High confidence in function and specificity; ribose ABC transporter substrate binding protein RbsB 778841 rbsB 4796819 rbsB Lactococcus lactis subsp. cremoris MG1363 ribose ABC transporter substrate binding protein RbsB YP_001032123.1 777867 D 416870 CDS YP_001032124.1 125623641 4799133 complement(779032..780165) 1 NC_009004.1 PF00589: Phage integrase; High confidence in function and specificity; integrase 780165 ps301 4799133 ps301 Lactococcus lactis subsp. cremoris MG1363 integrase YP_001032124.1 779032 R 416870 CDS YP_001032125.1 125623642 4797812 complement(780291..780917) 1 NC_009004.1 hypothetical protein 780917 ps302 4797812 ps302 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032125.1 780291 R 416870 CDS YP_001032126.1 125623643 4798001 complement(780974..781411) 1 NC_009004.1 PF06114: Protein of unknown function DUF955; hypothetical protein 781411 ps303 4798001 ps303 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032126.1 780974 R 416870 CDS YP_001032127.1 125623644 4797181 complement(781408..781905) 1 NC_009004.1 repressor, IPR010982: Lambda repressor-like, DNA- binding, PF01381: Helix-turn-helix; High confidence in function and specificity; hypothetical protein 781905 ps304 4797181 ps304 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032127.1 781408 R 416870 CDS YP_001032128.1 125623645 4797179 complement(782307..783116) 1 NC_009004.1 hypothetical protein 783116 ps305 4797179 ps305 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032128.1 782307 R 416870 CDS YP_001032129.1 125623646 4797172 783270..783521 1 NC_009004.1 IPR010982: Lambda repressor-like, DNA-binding; hypothetical protein 783521 ps306 4797172 ps306 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032129.1 783270 D 416870 CDS YP_001032130.1 125623647 4797171 783536..783754 1 NC_009004.1 hypothetical protein 783754 ps307 4797171 ps307 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032130.1 783536 D 416870 CDS YP_001032131.1 125623648 4797169 783764..784477 1 NC_009004.1 antirepressor; hypothetical protein 784477 ps308 4797169 ps308 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032131.1 783764 D 416870 CDS YP_001032132.1 125623649 4797158 784490..784726 1 NC_009004.1 hypothetical protein 784726 ps309 4797158 ps309 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032132.1 784490 D 416870 CDS YP_001032133.1 125623650 4798285 784880..785113 1 NC_009004.1 hypothetical protein 785113 ps310 4798285 ps310 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032133.1 784880 D 416870 CDS YP_001032134.1 125623651 4798310 complement(785068..785346) 1 NC_009004.1 hypothetical protein 785346 ps311 4798310 ps311 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032134.1 785068 R 416870 CDS YP_001032135.1 125623652 4798308 785452..785700 1 NC_009004.1 hypothetical protein 785700 ps312 4798308 ps312 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032135.1 785452 D 416870 CDS YP_001032136.1 125623653 4798298 785697..785873 1 NC_009004.1 PF04761: Lactococcus bacteriophage transcription regulator; transcriptional regulator 785873 ps313 4798298 ps313 Lactococcus lactis subsp. cremoris MG1363 transcriptional regulator YP_001032136.1 785697 D 416870 CDS YP_001032137.1 125623654 4797319 785978..786496 1 NC_009004.1 PF07211: Protein of unknown function DUF1417; hypothetical protein 786496 ps314 4797319 ps314 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032137.1 785978 D 416870 CDS YP_001032138.1 125623655 4797293 786505..787224 1 NC_009004.1 TIGR01618: phage nucleotide-binding protein; Conserved hypothetical protein; hypothetical protein 787224 ps315 4797293 ps315 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032138.1 786505 D 416870 CDS YP_001032139.1 125623656 4797289 787224..787727 1 NC_009004.1 ssDNA binding protein; hypothetical protein 787727 ps316 4797289 ps316 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032139.1 787224 D 416870 CDS YP_001032140.1 125623657 4797266 787863..788702 1 NC_009004.1 PF06926: replisome organiser protein C- terminus; Family membership; replisome organizer protein 788702 ps317 4797266 ps317 Lactococcus lactis subsp. cremoris MG1363 replisome organizer protein YP_001032140.1 787863 D 416870 CDS YP_001032141.1 125623658 4797249 788712..789596 1 NC_009004.1 DnaC protein; hypothetical protein 789596 ps318 4797249 ps318 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032141.1 788712 D 416870 CDS YP_001032142.1 125623659 4797246 789593..789757 1 NC_009004.1 hypothetical protein 789757 ps319 4797246 ps319 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032142.1 789593 D 416870 CDS YP_001032143.1 125623660 4798514 789681..790166 1 NC_009004.1 holliday junction resolvase, PF05866: Endodeoxyribonuclease RusA; High confidence in function and specificity; hypothetical protein 790166 ps320 4798514 ps320 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032143.1 789681 D 416870 CDS YP_001032144.1 125623661 4798423 790167..790406 1 NC_009004.1 PF06275: Protein of unknown function DUF1031; hypothetical protein 790406 ps321 4798423 ps321 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032144.1 790167 D 416870 CDS YP_001032145.1 125623662 4798424 790512..791036 1 NC_009004.1 hypothetical protein 791036 ps322 4798424 ps322 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032145.1 790512 D 416870 CDS YP_001032146.1 125623663 4797954 791050..791256 1 NC_009004.1 PF06563: Protein of unknown function DUF1125; hypothetical protein 791256 ps323 4797954 ps323 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032146.1 791050 D 416870 CDS YP_001032147.1 125623664 4797187 791249..791797 1 NC_009004.1 PF07852: Protein of unknown function DUF1642; hypothetical protein 791797 ps324 4797187 ps324 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032147.1 791249 D 416870 CDS YP_001032148.1 125623665 4797947 791794..792213 1 NC_009004.1 PF00692: dUTPase, TIGR00576: deoxyuridine 5'- triphosphate nucleotidohydrolase (dut); High confidence in function and specificity; deoxyuridine 5'-triphosphate nucleotidohydrolase 792213 ps325 4797947 ps325 Lactococcus lactis subsp. cremoris MG1363 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_001032148.1 791794 D 416870 CDS YP_001032149.1 125623666 4797935 792216..792554 1 NC_009004.1 hypothetical protein 792554 ps326 4797935 ps326 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032149.1 792216 D 416870 CDS YP_001032150.1 125623667 4797895 792551..793231 1 NC_009004.1 hypothetical protein 793231 ps327 4797895 ps327 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032150.1 792551 D 416870 CDS YP_001032151.1 125623668 4797887 793311..793529 1 NC_009004.1 hypothetical protein 793529 ps328 4797887 ps328 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032151.1 793311 D 416870 CDS YP_001032152.1 125623669 4797866 793526..793699 1 NC_009004.1 hypothetical protein 793699 ps329 4797866 ps329 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032152.1 793526 D 416870 CDS YP_001032153.1 125623670 4797862 794054..794479 1 NC_009004.1 PF05263: Protein of unknown function DUF722; hypothetical protein 794479 ps330 4797862 ps330 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032153.1 794054 D 416870 CDS YP_001032154.1 125623671 4797859 794656..795879 1 NC_009004.1 PF00665: Integrase core domain; Conserved hypothetical protein; transposase for insertion sequence element IS712D 795879 tnp712 4797859 tnp712 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS712D YP_001032154.1 794656 D 416870 CDS YP_001032155.1 125623672 4796975 795891..796649 1 NC_009004.1 PF01695: IstB-like ATP-binding protein; Conserved hypothetical protein; transposase helper protein for IS712D 796649 4796975 llmg_0823 Lactococcus lactis subsp. cremoris MG1363 transposase helper protein for IS712D YP_001032155.1 795891 D 416870 CDS YP_001032156.1 125623673 4797306 797030..797542 1 NC_009004.1 PF03592: Terminase small subunit; High confidence in function and specificity; terminase small subunit 797542 ps333 4797306 ps333 Lactococcus lactis subsp. cremoris MG1363 terminase small subunit YP_001032156.1 797030 D 416870 CDS YP_001032157.1 125623674 4797856 797532..798767 1 NC_009004.1 TIGR01547: phage terminase, large subunit, PBSX family; terminase large subunit 798767 ps334 4797856 ps334 Lactococcus lactis subsp. cremoris MG1363 terminase large subunit YP_001032157.1 797532 D 416870 CDS YP_001032158.1 125623675 4797851 798777..800285 1 NC_009004.1 PF05133: Phage portal protein, SPP1 Gp6-like, TIGR01538: phage portal protein, SPP1 family; Conserved hypothetical protein; portal protein 800285 ps335 4797851 ps335 Lactococcus lactis subsp. cremoris MG1363 portal protein YP_001032158.1 798777 D 416870 CDS YP_001032159.1 125623676 4799018 800675..800962 1 NC_009004.1 PF04327: Protein of unknown function DUF464; Specificity unclear; hypothetical protein 800962 ps336 4799018 ps336 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032159.1 800675 D 416870 CDS YP_001032160.1 125623677 4798477 800968..802065 1 NC_009004.1 TIGR01641 : phage head morphogenesis protein, SPP1 gp7 family; hypothetical protein 802065 ps337 4798477 ps337 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032160.1 800968 D 416870 CDS YP_001032161.1 125623678 4798550 802098..802628 1 NC_009004.1 hypothetical protein 802628 ps338 4798550 ps338 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032161.1 802098 D 416870 CDS YP_001032162.1 125623679 4799045 802688..802846 1 NC_009004.1 hypothetical protein 802846 ps339 4799045 ps339 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032162.1 802688 D 416870 CDS YP_001032163.1 125623680 4796801 complement(802843..803115) 1 NC_009004.1 hypothetical protein 803115 ps340 4796801 ps340 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032163.1 802843 R 416870 CDS YP_001032164.1 125623681 4799012 803292..803918 1 NC_009004.1 hypothetical protein 803918 ps341 4799012 ps341 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032164.1 803292 D 416870 CDS YP_001032165.1 125623682 4798568 803930..805048 1 NC_009004.1 major head protein 805048 ps342 4798568 ps342 Lactococcus lactis subsp. cremoris MG1363 major head protein YP_001032165.1 803930 D 416870 CDS YP_001032166.1 125623683 4799066 805069..805401 1 NC_009004.1 hypothetical protein 805401 ps343 4799066 ps343 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032166.1 805069 D 416870 CDS YP_001032167.1 125623684 4799059 805382..805735 1 NC_009004.1 hypothetical protein 805735 ps344 4799059 ps344 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032167.1 805382 D 416870 CDS YP_001032168.1 125623685 4798829 805719..806267 1 NC_009004.1 hypothetical protein 806267 ps345 4798829 ps345 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032168.1 805719 D 416870 CDS YP_001032169.1 125623686 4798896 806267..806629 1 NC_009004.1 hypothetical protein 806629 ps346 4798896 ps346 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032169.1 806267 D 416870 CDS YP_001032170.1 125623687 4798905 806642..807055 1 NC_009004.1 Conserved hypothetical protein; major tail protein 807055 ps347 4798905 ps347 Lactococcus lactis subsp. cremoris MG1363 major tail protein YP_001032170.1 806642 D 416870 CDS YP_001032171.1 125623688 4798913 807132..807542 1 NC_009004.1 hypothetical protein 807542 ps348 4798913 ps348 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032171.1 807132 D 416870 CDS YP_001032172.1 125623689 4798920 807629..807937 1 NC_009004.1 hypothetical protein 807937 ps349 4798920 ps349 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032172.1 807629 D 416870 CDS YP_001032173.1 125623690 4798124 807969..812669 1 NC_009004.1 minor tail protein; hypothetical protein 812669 ps350 4798124 ps350 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032173.1 807969 D 416870 CDS YP_001032174.1 125623691 4798277 812681..813046 1 NC_009004.1 hypothetical protein 813046 ps351 4798277 ps351 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032174.1 812681 D 416870 CDS YP_001032175.1 125623692 4798870 813058..815595 1 NC_009004.1 hypothetical protein 815595 ps352 4798870 ps352 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032175.1 813058 D 416870 CDS YP_001032176.1 125623693 4798400 815729..817222 1 NC_009004.1 hypothetical protein 817222 ps353 4798400 ps353 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032176.1 815729 D 416870 CDS YP_001032177.1 125623694 4797569 817303..817608 1 NC_009004.1 hypothetical protein 817608 ps354 4797569 ps354 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032177.1 817303 D 416870 CDS YP_001032178.1 125623695 4797440 817595..817819 1 NC_009004.1 holin 817819 ps355 4797440 ps355 Lactococcus lactis subsp. cremoris MG1363 holin YP_001032178.1 817595 D 416870 CDS YP_001032179.1 125623696 4798697 817816..819105 1 NC_009004.1 PF01183: Glycosyl hydrolases family 25; High confidence in function and specificity; endolysin 819105 ps356 4798697 ps356 Lactococcus lactis subsp. cremoris MG1363 endolysin YP_001032179.1 817816 D 416870 CDS YP_001032180.1 125623697 4798717 819287..820246 1 NC_009004.1 PF07751: Abi-like protein; hypothetical protein 820246 ps357 4798717 ps357 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032180.1 819287 D 416870 CDS YP_001032181.1 125623698 4798701 820437..820673 1 NC_009004.1 hypothetical protein 820673 ps358 4798701 ps358 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032181.1 820437 D 416870 CDS YP_001032182.1 125623699 4797490 821178..821600 1 NC_009004.1 hypothetical protein 821600 4797490 llmg_0854 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032182.1 821178 D 416870 CDS YP_001032183.1 125623700 4798529 821605..821910 1 NC_009004.1 hypothetical protein 821910 4798529 llmg_0855 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032183.1 821605 D 416870 CDS YP_001032184.1 125623701 4798367 822270..823712 1 NC_009004.1 multidrug transporter PF07690: Major Facilitator Superfamily; hypothetical protein 823712 4798367 llmg_0856 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032184.1 822270 D 416870 CDS YP_001032185.1 125623702 4798361 complement(823766..824446) 1 NC_009004.1 Bacterial regulatory proteins, gntR family; High confidence in function and specificity; GntR family transcriptional regulator 824446 kdgR 4798361 kdgR Lactococcus lactis subsp. cremoris MG1363 GntR family transcriptional regulator YP_001032185.1 823766 R 416870 CDS YP_001032186.1 125623703 4797622 824842..826476 1 NC_009004.1 High confidence in function and specificity; fructuronate reductase 826476 uxuB 4797622 uxuB Lactococcus lactis subsp. cremoris MG1363 fructuronate reductase YP_001032186.1 824842 D 416870 CDS YP_001032187.1 125623704 4797290 826582..827658 1 NC_009004.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 827658 uxuA 4797290 uxuA Lactococcus lactis subsp. cremoris MG1363 mannonate dehydratase YP_001032187.1 826582 D 416870 CDS YP_001032188.1 125623705 4797304 827843..829369 1 NC_009004.1 Major facilitator superfamily MFS_1; High confidence in function and specificity; Na-galactoside symporter 829369 uxuT 4797304 uxuT Lactococcus lactis subsp. cremoris MG1363 Na-galactoside symporter YP_001032188.1 827843 D 416870 CDS YP_001032189.1 125623706 4798515 829429..830310 1 NC_009004.1 Galactose mutarotase-like; Function unclear; hypothetical protein 830310 4798515 llmg_0861 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032189.1 829429 D 416870 CDS YP_001032190.1 125623707 4798859 830323..831741 1 NC_009004.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase 831741 uxaC 4798859 uxaC Lactococcus lactis subsp. cremoris MG1363 glucuronate isomerase YP_001032190.1 830323 D 416870 CDS YP_001032191.1 125623708 4797709 832691..833332 1 NC_009004.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 833332 kdgA 4797709 kdgA Lactococcus lactis subsp. cremoris MG1363 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase YP_001032191.1 832691 D 416870 CDS YP_001032192.1 125623709 4797627 833507..835447 1 NC_009004.1 Family membership; BglG family transcriptional antiterminator 835447 4797627 llmg_0865 Lactococcus lactis subsp. cremoris MG1363 BglG family transcriptional antiterminator YP_001032192.1 833507 D 416870 CDS YP_001032193.1 125623710 4798857 835449..835748 1 NC_009004.1 High confidence in function and specificity; pentitol PTS system transporter subunit IIB 835748 4798857 llmg_0866 Lactococcus lactis subsp. cremoris MG1363 pentitol PTS system transporter subunit IIB YP_001032193.1 835449 D 416870 CDS YP_001032194.1 125623711 4798849 835801..837201 1 NC_009004.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 837201 ulaA 4798849 ulaA Lactococcus lactis subsp. cremoris MG1363 PTS system ascorbate-specific transporter subunit IIC YP_001032194.1 835801 D 416870 CDS YP_001032195.1 125623712 4798845 837369..839345 1 NC_009004.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 839345 tkt 4798845 tkt Lactococcus lactis subsp. cremoris MG1363 transketolase YP_001032195.1 837369 D 416870 CDS YP_001032196.1 125623713 4797080 839513..839764 1 NC_009004.1 hypothetical protein 839764 4797080 llmg_0869 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032196.1 839513 D 416870 CDS YP_001032197.1 125623714 4798840 840113..840976 1 NC_009004.1 Similar to glycerol uptake facilitator glpF; Function unclear; transporter 840976 4798840 llmg_0870 Lactococcus lactis subsp. cremoris MG1363 transporter YP_001032197.1 840113 D 416870 CDS YP_001032198.1 125623715 4798837 841072..842157 1 NC_009004.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 842157 asd 4798837 asd Lactococcus lactis subsp. cremoris MG1363 aspartate-semialdehyde dehydrogenase YP_001032198.1 841072 D 416870 CDS YP_001032199.1 125623716 4797224 842158..842625 1 NC_009004.1 contains NUDIX domain; Family membership; (di)nucleoside polyphosphate hydrolase 842625 4797224 llmg_0872 Lactococcus lactis subsp. cremoris MG1363 (di)nucleoside polyphosphate hydrolase YP_001032199.1 842158 D 416870 CDS YP_001032200.1 125623717 4798825 842612..843067 1 NC_009004.1 contains NUDIX domain; High confidence in function and specificity; (di)nucleoside polyphosphate hydrolase 843067 4798825 llmg_0873 Lactococcus lactis subsp. cremoris MG1363 (di)nucleoside polyphosphate hydrolase YP_001032200.1 842612 D 416870 CDS YP_001032201.1 125623718 4798822 843396..844289 1 NC_009004.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 844289 dapA 4798822 dapA Lactococcus lactis subsp. cremoris MG1363 dihydrodipicolinate synthase YP_001032201.1 843396 D 416870 CDS YP_001032202.1 125623719 4798874 complement(844329..845000) 1 NC_009004.1 MgtC/SapB family protein; Family membership; cation-transporting ATPase 845000 4798874 llmg_0875 Lactococcus lactis subsp. cremoris MG1363 cation-transporting ATPase YP_001032202.1 844329 R 416870 CDS YP_001032203.1 125623720 4798814 845351..847063 1 NC_009004.1 Family membership; metallo-beta-lactamase superfamily protein 847063 4798814 llmg_0876 Lactococcus lactis subsp. cremoris MG1363 metallo-beta-lactamase superfamily protein YP_001032203.1 845351 D 416870 CDS YP_001032204.1 125623721 4798810 847112..850345 1 NC_009004.1 Similar to Immunoglobulin A1 protease precursor; Conserved hypothetical protein; hypothetical protein 850345 4798810 llmg_0877 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032204.1 847112 D 416870 CDS YP_001032205.1 125623722 4798800 850424..851980 1 NC_009004.1 Signal recognition particle 54 kDa protein 2 (SRP54); High confidence in function and specificity; signal recognition particle protein 851980 ffh 4798800 ffh Lactococcus lactis subsp. cremoris MG1363 signal recognition particle protein YP_001032205.1 850424 D 416870 CDS YP_001032206.1 125623723 4797138 complement(852014..852556) 1 NC_009004.1 GCN5-related N-acetyltransferase; High confidence in function and specificity; spermidine acetyltransferase 852556 speG 4797138 speG Lactococcus lactis subsp. cremoris MG1363 spermidine acetyltransferase YP_001032206.1 852014 R 416870 CDS YP_001032207.1 125623724 4797342 complement(852641..853213) 1 NC_009004.1 High confidence in function and specificity; oxidoreductase 853213 4797342 llmg_0880 Lactococcus lactis subsp. cremoris MG1363 oxidoreductase YP_001032207.1 852641 R 416870 CDS YP_001032208.1 125623725 4798797 853408..854115 1 NC_009004.1 Conserved hypothetical protein; branched chain amino acid ABC transporter 854115 azlC 4798797 azlC Lactococcus lactis subsp. cremoris MG1363 branched chain amino acid ABC transporter YP_001032208.1 853408 D 416870 CDS YP_001032209.1 125623726 4798632 854102..854428 1 NC_009004.1 Protein of unknown function DUF931; Conserved hypothetical protein; hypothetical protein 854428 4798632 llmg_0882 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032209.1 854102 D 416870 CDS YP_001032210.1 125623727 4798791 854545..854787 1 NC_009004.1 hypothetical protein 854787 4798791 llmg_0883 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032210.1 854545 D 416870 CDS YP_001032211.1 125623728 4798786 854784..856241 1 NC_009004.1 Protein of unknown function DUF438; hypothetical protein 856241 4798786 llmg_0884 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032211.1 854784 D 416870 CDS YP_001032212.1 125623729 4798779 856402..857208 1 NC_009004.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 857208 proB 4798779 proB Lactococcus lactis subsp. cremoris MG1363 gamma-glutamyl kinase YP_001032212.1 856402 D 416870 CDS YP_001032213.1 125623730 4797068 857316..858560 1 NC_009004.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 858560 proA 4797068 proA Lactococcus lactis subsp. cremoris MG1363 gamma-glutamyl phosphate reductase YP_001032213.1 857316 D 416870 CDS YP_001032214.1 125623731 4797117 complement(858798..859715) 1 NC_009004.1 CDF: cation diffusion facilitator family transporter; Specificity unclear; cation transport protein 859715 4797117 llmg_0887 Lactococcus lactis subsp. cremoris MG1363 cation transport protein YP_001032214.1 858798 R 416870 CDS YP_001032215.1 125623732 4798773 complement(859705..860004) 1 NC_009004.1 Function unclear; ArsR family transcriptional regulator 860004 rarA 4798773 rarA Lactococcus lactis subsp. cremoris MG1363 ArsR family transcriptional regulator YP_001032215.1 859705 R 416870 CDS YP_001032216.1 125623733 4798628 860109..860807 1 NC_009004.1 hypothetical protein 860807 4798628 llmg_0889 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032216.1 860109 D 416870 CDS YP_001032217.1 125623734 4799051 861083..861604 1 NC_009004.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase 861604 pyrR 4799051 pyrR Lactococcus lactis subsp. cremoris MG1363 bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase YP_001032217.1 861083 D 416870 CDS YP_001032218.1 125623735 4798922 861704..862996 1 NC_009004.1 High confidence in function and specificity; uracil permease 862996 pyrP 4798922 pyrP Lactococcus lactis subsp. cremoris MG1363 uracil permease YP_001032218.1 861704 D 416870 CDS YP_001032219.1 125623736 4798862 863245..864177 1 NC_009004.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase 864177 pyrB 4798862 pyrB Lactococcus lactis subsp. cremoris MG1363 aspartate carbamoyltransferase YP_001032219.1 863245 D 416870 CDS YP_001032220.1 125623737 4798479 864265..865338 1 NC_009004.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 865338 carA 4798479 carA Lactococcus lactis subsp. cremoris MG1363 carbamoyl phosphate synthase small subunit YP_001032220.1 864265 D 416870 CDS YP_001032221.1 125623738 4797643 complement(865499..865771) 1 NC_009004.1 hypothetical protein 865771 4797643 llmg_0895 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032221.1 865499 R 416870 CDS YP_001032222.1 125623739 4798464 complement(865869..866270) 1 NC_009004.1 phage gene; hypothetical protein 866270 4798464 llmg_0896 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032222.1 865869 R 416870 CDS YP_001032223.1 125623740 4798467 complement(866339..867028) 1 NC_009004.1 Protein of unknown function DUF1535; Conserved hypothetical protein; hypothetical protein 867028 4798467 llmg_0897 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032223.1 866339 R 416870 CDS YP_001032224.1 125623741 4797602 867411..867572 1 NC_009004.1 hypothetical protein 867572 4797602 llmg_0898 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032224.1 867411 D 416870 CDS YP_001032225.1 125623742 4797710 867654..867956 1 NC_009004.1 hypothetical protein 867956 4797710 llmg_0899 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032225.1 867654 D 416870 CDS YP_001032226.1 125623743 4798595 868074..868334 1 NC_009004.1 helper protein for IS981; hypothetical protein 868334 ymbI 4798595 ymbI Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032226.1 868074 D 416870 CDS YP_001032227.1 125623744 4798328 868346..869185 1 NC_009004.1 Integrase, catalytic region; High confidence in function and specificity; transposase for insertion sequence element IS981H 869185 tnp981 4798328 tnp981 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS981H YP_001032227.1 868346 D 416870 CDS YP_001032228.1 125623745 4796956 869928..870332 1 NC_009004.1 Similar to low molecular weight phosphotyrosine protein phosphatases; High confidence in function and specificity; arsenate reductase 870332 arsC 4796956 arsC Lactococcus lactis subsp. cremoris MG1363 arsenate reductase YP_001032228.1 869928 D 416870 CDS YP_001032229.1 125623746 4798256 870444..871280 1 NC_009004.1 Family membership; serine/threonine phosphatase 871280 4798256 llmg_0903 Lactococcus lactis subsp. cremoris MG1363 serine/threonine phosphatase YP_001032229.1 870444 D 416870 CDS YP_001032230.1 125623747 4798606 871373..872284 1 NC_009004.1 contains CHAP domain; Family membership; hypothetical protein 872284 4798606 llmg_0904 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032230.1 871373 D 416870 CDS YP_001032231.1 125623748 4798600 872521..872883 1 NC_009004.1 hypothetical protein 872883 4798600 llmg_0905 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032231.1 872521 D 416870 CDS YP_001032232.1 125623749 4798758 873207..873452 1 NC_009004.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 873452 rpmE2 4798758 rpmE2 Lactococcus lactis subsp. cremoris MG1363 50S ribosomal protein L31 YP_001032232.1 873207 D 416870 CDS YP_001032233.1 125623750 4798245 873585..874115 1 NC_009004.1 Predicted metal-binding, possibly nucleic acid- binding protein, Protein of unknown function DUF177; Conserved hypothetical protein; ORF2; hypothetical protein 874115 4798245 llmg_0907 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032233.1 873585 D 416870 CDS YP_001032234.1 125623751 4798770 874271..874963 1 NC_009004.1 Contains response regulator receiver domain; High confidence in function and specificity; two-component system regulator llrA 874963 llrA 4798770 llrA Lactococcus lactis subsp. cremoris MG1363 two-component system regulator llrA YP_001032234.1 874271 D 416870 CDS YP_001032235.1 125623752 4796692 874950..876440 1 NC_009004.1 High confidence in function and specificity; sensor protein kinase kinA 876440 kinA 4796692 kinA Lactococcus lactis subsp. cremoris MG1363 sensor protein kinase kinA YP_001032235.1 874950 D 416870 CDS YP_001032236.1 125623753 4796642 876626..877867 1 NC_009004.1 High confidence in function and specificity; ammonium transporter 877867 amtB 4796642 amtB Lactococcus lactis subsp. cremoris MG1363 ammonium transporter YP_001032236.1 876626 D 416870 CDS YP_001032237.1 125623754 4799025 877949..878290 1 NC_009004.1 High confidence in function and specificity; nitrogen regulatory protein P-II 878290 glnB 4799025 glnB Lactococcus lactis subsp. cremoris MG1363 nitrogen regulatory protein P-II YP_001032237.1 877949 D 416870 CDS YP_001032238.1 125623755 4797892 878459..879808 1 NC_009004.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 879808 murD 4797892 murD Lactococcus lactis subsp. cremoris MG1363 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_001032238.1 878459 D 416870 CDS YP_001032239.1 125623756 4797430 880051..881124 1 NC_009004.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 881124 murG 4797430 murG Lactococcus lactis subsp. cremoris MG1363 undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase YP_001032239.1 880051 D 416870 CDS YP_001032240.1 125623757 4796917 881125..882291 1 NC_009004.1 High confidence in function and specificity; cell division protein FtsQ 882291 ftsQ 4796917 ftsQ Lactococcus lactis subsp. cremoris MG1363 cell division protein FtsQ YP_001032240.1 881125 D 416870 CDS YP_001032241.1 125623758 4798413 882441..883754 1 NC_009004.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 883754 obgE 4798413 obgE Lactococcus lactis subsp. cremoris MG1363 GTPase ObgE YP_001032241.1 882441 D 416870 CDS YP_001032242.1 125623759 4797452 883782..883952 1 NC_009004.1 hypothetical protein 883952 4797452 llmg_0916 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032242.1 883782 D 416870 CDS YP_001032243.1 125623760 4797537 complement(884001..884603) 1 NC_009004.1 hypothetical protein 884603 4797537 llmg_0917 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032243.1 884001 R 416870 CDS YP_001032244.1 125623761 4797558 884971..885270 1 NC_009004.1 hypothetical protein 885270 4797558 llmg_0918 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032244.1 884971 D 416870 CDS YP_001032245.1 125623762 4797515 886205..886996 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 886996 4797515 llmg_0920 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032245.1 886205 D 416870 CDS YP_001032246.1 125623763 4798347 887034..887792 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 887792 4798347 llmg_0921 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032246.1 887034 D 416870 CDS YP_001032247.1 125623764 4796853 887830..888585 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 888585 4796853 llmg_0922 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032247.1 887830 D 416870 CDS YP_001032248.1 125623765 4797510 893584..894645 1 NC_009004.1 Bacterial protein of unknown function DUF916, Similar to cell wall surface anchor family protein; hypothetical protein 894645 4797510 llmg_0924 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032248.1 893584 D 416870 CDS YP_001032249.1 125623766 4798817 894809..895120 1 NC_009004.1 Lambda repressor-like, DNA-binding; Family membership; transcriptional regulator 895120 4798817 llmg_0925 Lactococcus lactis subsp. cremoris MG1363 transcriptional regulator YP_001032249.1 894809 D 416870 CDS YP_001032250.1 125623767 4798830 complement(895195..896235) 1 NC_009004.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 896235 queA 4798830 queA Lactococcus lactis subsp. cremoris MG1363 S-adenosylmethionine--tRNA ribosyltransferase-isomerase YP_001032250.1 895195 R 416870 CDS YP_001032251.1 125623768 4799055 896558..897529 1 NC_009004.1 Esterase/lipase/thioesterase, conserved secreted hypothetical protein; possible alpha/beta hydrolase; Family membership; extracellular hydrolase 897529 4799055 llmg_0927 Lactococcus lactis subsp. cremoris MG1363 extracellular hydrolase YP_001032251.1 896558 D 416870 CDS YP_001032252.1 125623769 4797686 897703..898410 1 NC_009004.1 Glucosamine-6-phosphate deaminase; High confidence in function and specificity; glucosamine-6-phosphate isomerase 898410 nagB 4797686 nagB Lactococcus lactis subsp. cremoris MG1363 glucosamine-6-phosphate isomerase YP_001032252.1 897703 D 416870 CDS YP_001032253.1 125623770 4797025 complement(898471..899625) 1 NC_009004.1 High confidence in function and specificity; hydroxymethylglutaryl-CoA synthase 899625 hmcM 4797025 hmcM Lactococcus lactis subsp. cremoris MG1363 hydroxymethylglutaryl-CoA synthase YP_001032253.1 898471 R 416870 CDS YP_001032254.1 125623771 4796672 899909..901069 1 NC_009004.1 High confidence in function and specificity; ThiL protein 901069 thiL 4796672 thiL Lactococcus lactis subsp. cremoris MG1363 ThiL protein YP_001032254.1 899909 D 416870 CDS YP_001032255.1 125623772 4797030 901117..902349 1 NC_009004.1 High confidence in function and specificity; MvaA protein 902349 mvaA 4797030 mvaA Lactococcus lactis subsp. cremoris MG1363 MvaA protein YP_001032255.1 901117 D 416870 CDS YP_001032256.1 125623773 4798236 902434..902706 1 NC_009004.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 902706 rpsP 4798236 rpsP Lactococcus lactis subsp. cremoris MG1363 30S ribosomal protein S16 YP_001032256.1 902434 D 416870 CDS YP_001032257.1 125623774 4798407 902802..903041 1 NC_009004.1 contains KH domain (SSF54814); RNA binding protein 903041 4798407 llmg_0933 Lactococcus lactis subsp. cremoris MG1363 RNA binding protein YP_001032257.1 902802 D 416870 CDS YP_001032258.1 125623775 4797693 903241..904197 1 NC_009004.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 904197 hemH 4797693 hemH Lactococcus lactis subsp. cremoris MG1363 ferrochelatase YP_001032258.1 903241 D 416870 CDS YP_001032259.1 125623776 4797551 904223..905068 1 NC_009004.1 contains Alpha/beta hydrolase fold; High confidence in function and specificity; lysophospholipase 905068 4797551 llmg_0935 Lactococcus lactis subsp. cremoris MG1363 lysophospholipase YP_001032259.1 904223 D 416870 CDS YP_001032260.1 125623777 4797724 905253..905768 1 NC_009004.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 905768 rimM 4797724 rimM Lactococcus lactis subsp. cremoris MG1363 16S rRNA-processing protein RimM YP_001032260.1 905253 D 416870 CDS YP_001032261.1 125623778 4796933 905761..906516 1 NC_009004.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 906516 trmD 4796933 trmD Lactococcus lactis subsp. cremoris MG1363 tRNA (guanine-N(1)-)-methyltransferase YP_001032261.1 905761 D 416870 CDS YP_001032262.1 125623779 4798060 906642..907034 1 NC_009004.1 Protein of unknown function DUF1149; hypothetical protein 907034 4798060 llmg_0938 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032262.1 906642 D 416870 CDS YP_001032263.1 125623780 4796661 907051..907896 1 NC_009004.1 degV family protein; hypothetical protein 907896 4796661 llmg_0939 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032263.1 907051 D 416870 CDS YP_001032264.1 125623781 4796683 908026..908808 1 NC_009004.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 908808 dapB 4796683 dapB Lactococcus lactis subsp. cremoris MG1363 dihydrodipicolinate reductase YP_001032264.1 908026 D 416870 CDS YP_001032265.1 125623782 4798875 908874..909416 1 NC_009004.1 GCN5-related N-acetyltransferase; Family membership; acetyltransferase 909416 4798875 llmg_0941 Lactococcus lactis subsp. cremoris MG1363 acetyltransferase YP_001032265.1 908874 D 416870 CDS YP_001032266.1 125623783 4796595 909616..910824 1 NC_009004.1 catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity; tRNA CCA-pyrophosphorylase 910824 papL 4796595 papL Lactococcus lactis subsp. cremoris MG1363 tRNA CCA-pyrophosphorylase YP_001032266.1 909616 D 416870 CDS YP_001032267.1 125623784 4799071 910947..912371 1 NC_009004.1 High confidence in function and specificity; PepDB protein 912371 pepDB 4799071 pepDB Lactococcus lactis subsp. cremoris MG1363 PepDB protein YP_001032267.1 910947 D 416870 CDS YP_001032268.1 125623785 4798138 912482..913000 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 913000 4798138 llmg_0944 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032268.1 912482 D 416870 CDS YP_001032269.1 125623786 4796640 913106..914185 1 NC_009004.1 High confidence in function and specificity; glycerol dehydrogenase 914185 4796640 llmg_0945 Lactococcus lactis subsp. cremoris MG1363 glycerol dehydrogenase YP_001032269.1 913106 D 416870 CDS YP_001032270.1 125623787 4797150 914269..915222 1 NC_009004.1 probable metCcysK operon transcriptional activator; Conserved hypothetical protein; HTH-type transcriptional regulator cmhR 915222 cmhR 4797150 cmhR Lactococcus lactis subsp. cremoris MG1363 HTH-type transcriptional regulator cmhR YP_001032270.1 914269 D 416870 CDS YP_001032271.1 125623788 4797288 915370..917241 1 NC_009004.1 Uup: ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter ATP-binding protein 917241 4797288 llmg_0948 Lactococcus lactis subsp. cremoris MG1363 ABC transporter ATP-binding protein YP_001032271.1 915370 D 416870 CDS YP_001032272.1 125623789 4799137 917454..918428 1 NC_009004.1 Family membership; oxidoreductase 918428 4799137 llmg_0950 Lactococcus lactis subsp. cremoris MG1363 oxidoreductase YP_001032272.1 917454 D 416870 CDS YP_001032273.1 125623790 4798561 complement(918439..918990) 1 NC_009004.1 High confidence in function and specificity; MsrA protein 918990 msrA 4798561 msrA Lactococcus lactis subsp. cremoris MG1363 MsrA protein YP_001032273.1 918439 R 416870 CDS YP_001032274.1 125623791 4798428 919131..920066 1 NC_009004.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; subclass 1A is a dimer formed by two identical PyrD subunits each containing an FMN group; dihydroorotate dehydrogenase 1A 920066 pyrDA 4798428 pyrDA Lactococcus lactis subsp. cremoris MG1363 dihydroorotate dehydrogenase 1A YP_001032274.1 919131 D 416870 CDS YP_001032275.1 125623792 4797712 920191..920898 1 NC_009004.1 Protein of unknown function DUF1113; Conserved hypothetical protein; hypothetical protein 920898 4797712 llmg_0953 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032275.1 920191 D 416870 CDS YP_001032276.1 125623793 4797033 920958..921227 1 NC_009004.1 hypothetical protein 921227 4797033 llmg_0954 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032276.1 920958 D 416870 CDS YP_001032277.1 125623794 4797113 921340..922386 1 NC_009004.1 PF00107.12: Zinc-containing alcohol dehydrogenase superfamily; High confidence in function and specificity; alcohol dehydrogenase 922386 4797113 llmg_0955 Lactococcus lactis subsp. cremoris MG1363 alcohol dehydrogenase YP_001032277.1 921340 D 416870 CDS YP_001032278.1 125623795 4797000 complement(922479..923477) 1 NC_009004.1 Function unclear; LacI family transcriptional regulator 923477 4797000 llmg_0956 Lactococcus lactis subsp. cremoris MG1363 LacI family transcriptional regulator YP_001032278.1 922479 R 416870 CDS YP_001032279.1 125623796 4798557 923672..924322 1 NC_009004.1 High confidence in function and specificity; ribulose-phosphate 3-epimerase 924322 rpe2 4798557 rpe2 Lactococcus lactis subsp. cremoris MG1363 ribulose-phosphate 3-epimerase YP_001032279.1 923672 D 416870 CDS YP_001032280.1 125623797 4797255 924338..924787 1 NC_009004.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 924787 rpiB 4797255 rpiB Lactococcus lactis subsp. cremoris MG1363 ribose-5-phosphate isomerase B YP_001032280.1 924338 D 416870 CDS YP_001032281.1 125623798 4798440 924840..925394 1 NC_009004.1 Specificity unclear; beta-glucosidase 925394 4798440 llmg_0959 Lactococcus lactis subsp. cremoris MG1363 beta-glucosidase YP_001032281.1 924840 D 416870 CDS YP_001032282.1 125623799 4796942 925722..926204 1 NC_009004.1 High confidence in function and specificity; beta-glucosidase 926204 4796942 llmg_0960 Lactococcus lactis subsp. cremoris MG1363 beta-glucosidase YP_001032282.1 925722 D 416870 CDS YP_001032283.1 125623800 4796911 complement(926354..927256) 1 NC_009004.1 ROK_glcA_fam: ROK family protein ( glucokinase); High confidence in function and specificity; sugar kinase 927256 4796911 llmg_0961 Lactococcus lactis subsp. cremoris MG1363 sugar kinase YP_001032283.1 926354 R 416870 CDS YP_001032284.1 125623801 4797009 927365..928525 1 NC_009004.1 Function unclear; AraC family transcriptional regulator 928525 4797009 llmg_0962 Lactococcus lactis subsp. cremoris MG1363 AraC family transcriptional regulator YP_001032284.1 927365 D 416870 CDS YP_001032285.1 125623802 4796722 928743..930098 1 NC_009004.1 Similar to lactose/cellobiose PTS system IIC components; Specificity unclear; PTS system transporter subunit IIC 930098 4796722 llmg_0963 Lactococcus lactis subsp. cremoris MG1363 PTS system transporter subunit IIC YP_001032285.1 928743 D 416870 CDS YP_001032286.1 125623803 4798358 930251..931090 1 NC_009004.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 931090 thyA 4798358 thyA Lactococcus lactis subsp. cremoris MG1363 thymidylate synthase YP_001032286.1 930251 D 416870 CDS YP_001032287.1 125623804 4798156 931532..932221 1 NC_009004.1 hypothetical protein 932221 4798156 llmg_0965 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032287.1 931532 D 416870 CDS YP_001032288.1 125623805 4797263 932486..932932 1 NC_009004.1 High confidence in function and specificity; MarR family transcriptional regulator 932932 rmaI 4797263 rmaI Lactococcus lactis subsp. cremoris MG1363 MarR family transcriptional regulator YP_001032288.1 932486 D 416870 CDS YP_001032289.1 125623806 4797269 932929..934302 1 NC_009004.1 Major facilitator superfamily; Family membership; permease 934302 4797269 llmg_0967 Lactococcus lactis subsp. cremoris MG1363 permease YP_001032289.1 932929 D 416870 CDS YP_001032290.1 125623807 4798513 934523..935275 1 NC_009004.1 High confidence in function and specificity; oxidoreductase 935275 4798513 llmg_0968 Lactococcus lactis subsp. cremoris MG1363 oxidoreductase YP_001032290.1 934523 D 416870 CDS YP_001032291.1 125623808 4798006 935292..935660 1 NC_009004.1 hypothetical protein 935660 4798006 llmg_0969 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032291.1 935292 D 416870 CDS YP_001032292.1 125623809 4797313 935694..936008 1 NC_009004.1 Family membership; carboxymuconolactone decarboxylase 936008 4797313 llmg_0970 Lactococcus lactis subsp. cremoris MG1363 carboxymuconolactone decarboxylase YP_001032292.1 935694 D 416870 CDS YP_001032293.1 125623810 4797284 936021..936314 1 NC_009004.1 Contains dimeric alpha-beta barrel region; hypothetical protein 936314 yphI 4797284 yphI Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032293.1 936021 D 416870 CDS YP_001032294.1 125623811 4797261 936330..936737 1 NC_009004.1 SSF51182: RmlC-like cupin; hypothetical protein 936737 4797261 llmg_0972 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032294.1 936330 D 416870 CDS YP_001032295.1 125623812 4797955 936865..937587 1 NC_009004.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 937587 purC 4797955 purC Lactococcus lactis subsp. cremoris MG1363 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_001032295.1 936865 D 416870 CDS YP_001032296.1 125623813 4797723 937642..937908 1 NC_009004.1 High confidence in function and specificity; phosphoribosylformylglycinamidine synthetase PurS 937908 purS 4797723 purS Lactococcus lactis subsp. cremoris MG1363 phosphoribosylformylglycinamidine synthetase PurS YP_001032296.1 937642 D 416870 CDS YP_001032297.1 125623814 4797697 937905..938585 1 NC_009004.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase I 938585 purQ 4797697 purQ Lactococcus lactis subsp. cremoris MG1363 phosphoribosylformylglycinamidine synthase I YP_001032297.1 937905 D 416870 CDS YP_001032298.1 125623815 4797680 938802..941021 1 NC_009004.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase II 941021 purL 4797680 purL Lactococcus lactis subsp. cremoris MG1363 phosphoribosylformylglycinamidine synthase II YP_001032298.1 938802 D 416870 CDS YP_001032299.1 125623816 4797656 941006..942526 1 NC_009004.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 942526 purF 4797656 purF Lactococcus lactis subsp. cremoris MG1363 amidophosphoribosyltransferase YP_001032299.1 941006 D 416870 CDS YP_001032300.1 125623817 4797625 942840..943262 1 NC_009004.1 hypothetical protein 943262 4797625 llmg_0978 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032300.1 942840 D 416870 CDS YP_001032301.1 125623818 4796739 complement(943295..943678) 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 943678 4796739 llmg_0979 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032301.1 943295 R 416870 CDS YP_001032302.1 125623819 4796996 complement(943687..944595) 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 944595 4796996 llmg_0980 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032302.1 943687 R 416870 CDS YP_001032303.1 125623820 4797102 944625..944915 1 NC_009004.1 transposase helper protein for IS904; hypothetical protein 944915 4797102 llmg_0981 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032303.1 944625 D 416870 CDS YP_001032304.1 125623821 4798246 945825..946406 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 946406 4798246 llmg_0983 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032304.1 945825 D 416870 CDS YP_001032305.1 125623822 4797099 complement(947275..947388) 1 NC_009004.1 Similar to first 37 aa of L.lactis IL1403 protein ypgH; hypothetical protein 947388 4797099 llmg_0984 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032305.1 947275 R 416870 CDS YP_001032306.1 125623823 4796790 947599..948405 1 NC_009004.1 phage protein; Conserved hypothetical protein; hypothetical protein 948405 4796790 llmg_0985 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032306.1 947599 D 416870 CDS YP_001032307.1 125623824 4798162 948593..951196 1 NC_009004.1 High confidence in function and specificity; ATP-dependent Clp protease 951196 clpB 4798162 clpB Lactococcus lactis subsp. cremoris MG1363 ATP-dependent Clp protease YP_001032307.1 948593 D 416870 CDS YP_001032308.1 125623825 4797128 951380..952402 1 NC_009004.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 952402 purM 4797128 purM Lactococcus lactis subsp. cremoris MG1363 phosphoribosylaminoimidazole synthetase YP_001032308.1 951380 D 416870 CDS YP_001032309.1 125623826 4797665 952431..952979 1 NC_009004.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 952979 purN 4797665 purN Lactococcus lactis subsp. cremoris MG1363 phosphoribosylglycinamide formyltransferase YP_001032309.1 952431 D 416870 CDS YP_001032310.1 125623827 4797669 953119..954765 1 NC_009004.1 Family membership; ABC transporter ATP binding and permease 954765 4797669 llmg_0989 Lactococcus lactis subsp. cremoris MG1363 ABC transporter ATP binding and permease YP_001032310.1 953119 D 416870 CDS YP_001032311.1 125623828 4797354 complement(956132..956662) 1 NC_009004.1 Family membership; AcrR family transcriptional regulator 956662 4797354 llmg_0991 Lactococcus lactis subsp. cremoris MG1363 AcrR family transcriptional regulator YP_001032311.1 956132 R 416870 CDS YP_001032312.1 125623829 4796737 956790..957827 1 NC_009004.1 Family membership; nucleoside-diphosphate-sugar epimerase 957827 4796737 llmg_0992 Lactococcus lactis subsp. cremoris MG1363 nucleoside-diphosphate-sugar epimerase YP_001032312.1 956790 D 416870 CDS YP_001032313.1 125623830 4798208 957962..958504 1 NC_009004.1 PF00156.12: Phosphoribosyltransferase; High confidence in function and specificity; HprT protein 958504 hprT 4798208 hprT Lactococcus lactis subsp. cremoris MG1363 HprT protein YP_001032313.1 957962 D 416870 CDS YP_001032314.1 125623831 4797826 958681..960237 1 NC_009004.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 960237 purH 4797826 purH Lactococcus lactis subsp. cremoris MG1363 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_001032314.1 958681 D 416870 CDS YP_001032315.1 125623832 4797631 960356..961048 1 NC_009004.1 HAD-superfamily subfamily IA hydrolase; Family membership; hydrolase 961048 4797631 llmg_0995 Lactococcus lactis subsp. cremoris MG1363 hydrolase YP_001032315.1 960356 D 416870 CDS YP_001032316.1 125623833 4797504 complement(962586..963212) 1 NC_009004.1 Family membership; TetR family transcriptional regulator 963212 4797504 llmg_0996 Lactococcus lactis subsp. cremoris MG1363 TetR family transcriptional regulator YP_001032316.1 962586 R 416870 CDS YP_001032317.1 125623834 4798158 963606..964847 1 NC_009004.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 964847 purD 4798158 purD Lactococcus lactis subsp. cremoris MG1363 phosphoribosylamine--glycine ligase YP_001032317.1 963606 D 416870 CDS YP_001032318.1 125623835 4798482 964919..965611 1 NC_009004.1 TIGR01484: HAD-superfamily hydrolase, subfamily IIB; Family membership; hydrolase 965611 4798482 llmg_0998 Lactococcus lactis subsp. cremoris MG1363 hydrolase YP_001032318.1 964919 D 416870 CDS YP_001032319.1 125623836 4796643 965608..966093 1 NC_009004.1 High confidence in function and specificity; phosphoribosylaminoimidazole carboxylase catalytic subunit 966093 purE 4796643 purE Lactococcus lactis subsp. cremoris MG1363 phosphoribosylaminoimidazole carboxylase catalytic subunit YP_001032319.1 965608 D 416870 CDS YP_001032320.1 125623837 4797613 966149..967255 1 NC_009004.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 967255 purK 4797613 purK Lactococcus lactis subsp. cremoris MG1363 phosphoribosylaminoimidazole carboxylase ATPase subunit YP_001032320.1 966149 D 416870 CDS YP_001032321.1 125623838 4797646 complement(967411..968343) 1 NC_009004.1 Conserved hypothetical protein; xylose operon regulator 968343 xylR 4797646 xylR Lactococcus lactis subsp. cremoris MG1363 xylose operon regulator YP_001032321.1 967411 R 416870 CDS YP_001032322.1 125623839 4797279 968454..969149 1 NC_009004.1 High confidence in function and specificity; XylA protein 969149 xylA 4797279 xylA Lactococcus lactis subsp. cremoris MG1363 XylA protein YP_001032322.1 968454 D 416870 CDS YP_001032323.1 125623840 4797835 complement(969172..969852) 1 NC_009004.1 Integrase, catalytic region; High confidence in function and specificity; transposase for insertion sequence-like element IS1216 969852 tnp1216 4797835 tnp1216 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence-like element IS1216 YP_001032323.1 969172 R 416870 CDS YP_001032324.1 125623841 4797081 969894..970571 1 NC_009004.1 Specificity unclear; beta-glucosidase 970571 4797081 llmg_1004 Lactococcus lactis subsp. cremoris MG1363 beta-glucosidase YP_001032324.1 969894 D 416870 CDS YP_001032325.1 125623842 4798243 970613..971482 1 NC_009004.1 ROK_glcA_fam: ROK family protein ( glucokinase); Function unclear; sugar kinase 971482 4798243 llmg_1005 Lactococcus lactis subsp. cremoris MG1363 sugar kinase YP_001032325.1 970613 D 416870 CDS YP_001032326.1 125623843 4796921 971556..972431 1 NC_009004.1 High confidence in function and specificity; fructokinase 972431 scrK 4796921 scrK Lactococcus lactis subsp. cremoris MG1363 fructokinase YP_001032326.1 971556 D 416870 CDS YP_001032327.1 125623844 4798940 972415..972561 1 NC_009004.1 hypothetical protein 972561 4798940 llmg_1007 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032327.1 972415 D 416870 CDS YP_001032328.1 125623845 4797147 972641..974182 1 NC_009004.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 974182 guaA 4797147 guaA Lactococcus lactis subsp. cremoris MG1363 GMP synthase YP_001032328.1 972641 D 416870 CDS YP_001032329.1 125623846 4798767 974516..975406 1 NC_009004.1 High confidence in function and specificity; sugar ABC transporter substrate binding protein 975406 lplB 4798767 lplB Lactococcus lactis subsp. cremoris MG1363 sugar ABC transporter substrate binding protein YP_001032329.1 974516 D 416870 CDS YP_001032330.1 125623847 4796680 975417..976280 1 NC_009004.1 Conserved hypothetical protein; sugar ABC transporter permease 976280 lplC 4796680 lplC Lactococcus lactis subsp. cremoris MG1363 sugar ABC transporter permease YP_001032330.1 975417 D 416870 CDS YP_001032331.1 125623848 4797636 976352..977548 1 NC_009004.1 High confidence in function and specificity; sugar ABC transporter substrate-binding protein 977548 lplA 4797636 lplA Lactococcus lactis subsp. cremoris MG1363 sugar ABC transporter substrate-binding protein YP_001032331.1 976352 D 416870 CDS YP_001032332.1 125623849 4796730 977586..977987 1 NC_009004.1 Specificity unclear; ABC transporter substrate-binding protein 977987 4796730 llmg_1012 Lactococcus lactis subsp. cremoris MG1363 ABC transporter substrate-binding protein YP_001032332.1 977586 D 416870 CDS YP_001032333.1 125623850 4797107 978188..978376 1 NC_009004.1 hypothetical protein 978376 4797107 llmg_1013 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032333.1 978188 D 416870 CDS YP_001032334.1 125623851 4796905 978828..981218 1 NC_009004.1 Contains Proteinase inhibitor I11 ecotin domain (SSF49772); hypothetical protein 981218 4796905 llmg_1014 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032334.1 978828 D 416870 CDS YP_001032335.1 125623852 4797013 complement(981287..982666) 1 NC_009004.1 Similar to multi antimicrobial extrusion protein MatE; Conserved hypothetical protein; hypothetical protein 982666 ypbC 4797013 ypbC Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032335.1 981287 R 416870 CDS YP_001032336.1 125623853 4797438 complement(982765..983670) 1 NC_009004.1 Similar to CorA-like Mg2+ transporter proteins; Family membership; cationic transporter 983670 4797438 llmg_1016 Lactococcus lactis subsp. cremoris MG1363 cationic transporter YP_001032336.1 982765 R 416870 CDS YP_001032337.1 125623854 4798191 983847..984266 1 NC_009004.1 High confidence in function and specificity; MarR family transcriptional regulator 984266 rmaE 4798191 rmaE Lactococcus lactis subsp. cremoris MG1363 MarR family transcriptional regulator YP_001032337.1 983847 D 416870 CDS YP_001032338.1 125623855 4798834 complement(986437..987216) 1 NC_009004.1 Function unclear; oxidoreductase, short-chain dehydrogenase/reductase 987216 4798834 llmg_1019 Lactococcus lactis subsp. cremoris MG1363 oxidoreductase, short-chain dehydrogenase/reductase YP_001032338.1 986437 R 416870 CDS YP_001032339.1 125623856 4796908 987245..987679 1 NC_009004.1 High confidence in function and specificity; MerR family transcriptional regulator 987679 rmeB 4796908 rmeB Lactococcus lactis subsp. cremoris MG1363 MerR family transcriptional regulator YP_001032339.1 987245 D 416870 CDS YP_001032340.1 125623857 4796818 complement(987722..988609) 1 NC_009004.1 Protein of unknown function DUF6; Conserved hypothetical protein; hypothetical protein 988609 4796818 llmg_1021 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032340.1 987722 R 416870 CDS YP_001032341.1 125623858 4797355 complement(990101..990487) 1 NC_009004.1 High confidence in function and specificity; ferric uptake regulation protein 990487 fur 4797355 fur Lactococcus lactis subsp. cremoris MG1363 ferric uptake regulation protein YP_001032341.1 990101 R 416870 CDS YP_001032342.1 125623859 4798603 990614..991303 1 NC_009004.1 Integral membrane protein DUF125; Conserved hypothetical protein; hypothetical protein 991303 4798603 llmg_1024 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032342.1 990614 D 416870 CDS YP_001032343.1 125623860 4798417 991303..991983 1 NC_009004.1 Protein of unknown function DUF125; hypothetical protein 991983 4798417 llmg_1025 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032343.1 991303 D 416870 CDS YP_001032344.1 125623861 4797123 992059..992802 1 NC_009004.1 Family membership; methyltransferase 992802 4797123 llmg_1026 Lactococcus lactis subsp. cremoris MG1363 methyltransferase YP_001032344.1 992059 D 416870 CDS YP_001032345.1 125623862 4798214 992912..993331 1 NC_009004.1 Bacterial regulatory protein, MarR family; Family membership; MarR family transcriptional regulator 993331 rmaC 4798214 rmaC Lactococcus lactis subsp. cremoris MG1363 MarR family transcriptional regulator YP_001032345.1 992912 D 416870 CDS YP_001032346.1 125623863 4798633 993343..993981 1 NC_009004.1 Family membership; NAD(P)H nitroreductase 993981 4798633 llmg_1028 Lactococcus lactis subsp. cremoris MG1363 NAD(P)H nitroreductase YP_001032346.1 993343 D 416870 CDS YP_001032347.1 125623864 4798198 993996..994355 1 NC_009004.1 Protein of unknown function DUF1304; Conserved hypothetical protein; hypothetical protein 994355 4798198 llmg_1029 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032347.1 993996 D 416870 CDS YP_001032348.1 125623865 4798202 994809..996179 1 NC_009004.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 996179 trpE 4798202 trpE Lactococcus lactis subsp. cremoris MG1363 anthranilate synthase component I YP_001032348.1 994809 D 416870 CDS YP_001032349.1 125623866 4798654 996231..996812 1 NC_009004.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II 996812 trpG 4798654 trpG Lactococcus lactis subsp. cremoris MG1363 anthranilate synthase component II YP_001032349.1 996231 D 416870 CDS YP_001032350.1 125623867 4796969 996817..997824 1 NC_009004.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 997824 trpD 4796969 trpD Lactococcus lactis subsp. cremoris MG1363 anthranilate phosphoribosyltransferase YP_001032350.1 996817 D 416870 CDS YP_001032351.1 125623868 4797100 998610..998930 1 NC_009004.1 hypothetical protein 998930 4797100 llmg_1034 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032351.1 998610 D 416870 CDS YP_001032352.1 125623869 4797050 998956..999135 1 NC_009004.1 hypothetical protein 999135 4797050 llmg_1035 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032352.1 998956 D 416870 CDS YP_001032353.1 125623870 4798237 999434..999802 1 NC_009004.1 PF00903.12: Glyoxalase/bleomycin resistance protein/dioxygenase; Specificity unclear; lyase 999802 4798237 llmg_1037 Lactococcus lactis subsp. cremoris MG1363 lyase YP_001032353.1 999434 D 416870 CDS YP_001032354.1 125623871 4798085 999809..1000603 1 NC_009004.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; indole-3-glycerol phosphate synthase 1000603 trpC 4798085 trpC Lactococcus lactis subsp. cremoris MG1363 indole-3-glycerol phosphate synthase YP_001032354.1 999809 D 416870 CDS YP_001032355.1 125623872 4797036 1000593..1001651 1 NC_009004.1 High confidence in function and specificity; N-(5'-phosphoribosyl)anthranilate isomerase 1001651 trpF 4797036 trpF Lactococcus lactis subsp. cremoris MG1363 N-(5'-phosphoribosyl)anthranilate isomerase YP_001032355.1 1000593 D 416870 CDS YP_001032356.1 125623873 4796968 1001641..1002213 1 NC_009004.1 acetyltransferase 1002213 4796968 llmg_1040 Lactococcus lactis subsp. cremoris MG1363 acetyltransferase YP_001032356.1 1001641 D 416870 CDS YP_001032357.1 125623874 4798273 1002258..1003463 1 NC_009004.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1003463 trpB 4798273 trpB Lactococcus lactis subsp. cremoris MG1363 tryptophan synthase subunit beta YP_001032357.1 1002258 D 416870 CDS YP_001032358.1 125623875 4796674 1003463..1004224 1 NC_009004.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1004224 trpA 4796674 trpA Lactococcus lactis subsp. cremoris MG1363 tryptophan synthase subunit alpha YP_001032358.1 1003463 D 416870 CDS YP_001032359.1 125623876 4797495 1006599..1008509 1 NC_009004.1 High confidence in function and specificity; PTS system, beta-glucosides specific enzyme IIABC 1008509 bglP 4797495 bglP Lactococcus lactis subsp. cremoris MG1363 PTS system, beta-glucosides specific enzyme IIABC YP_001032359.1 1006599 D 416870 CDS YP_001032360.1 125623877 4797375 1008557..1009993 1 NC_009004.1 High confidence in function and specificity; beta-glucosidase 1009993 bglH 4797375 bglH Lactococcus lactis subsp. cremoris MG1363 beta-glucosidase YP_001032360.1 1008557 D 416870 CDS YP_001032361.1 125623878 4796846 1010159..1010779 1 NC_009004.1 repressor of the osmoprotectant uptake system; High confidence in function and specificity; transcriptional repressor BusR 1010779 busR 4796846 busR Lactococcus lactis subsp. cremoris MG1363 transcriptional repressor BusR YP_001032361.1 1010159 D 416870 CDS YP_001032362.1 125623879 4797706 1010991..1012214 1 NC_009004.1 High confidence in function and specificity; glycine betaine/proline ABC transporter 1012214 busAA 4797706 busAA Lactococcus lactis subsp. cremoris MG1363 glycine betaine/proline ABC transporter YP_001032362.1 1010991 D 416870 CDS YP_001032363.1 125623880 4797696 1012207..1013928 1 NC_009004.1 Conserved hypothetical protein; glycine betaine-binding periplasmic protein 1013928 busAB 4797696 busAB Lactococcus lactis subsp. cremoris MG1363 glycine betaine-binding periplasmic protein YP_001032363.1 1012207 D 416870 CDS YP_001032364.1 125623881 4797700 1014118..1014288 1 NC_009004.1 hypothetical protein 1014288 4797700 llmg_1050 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032364.1 1014118 D 416870 CDS YP_001032365.1 125623882 4797567 complement(1014345..1014920) 1 NC_009004.1 transcriptional regulator 1014920 4797567 llmg_1051 Lactococcus lactis subsp. cremoris MG1363 transcriptional regulator YP_001032365.1 1014345 R 416870 CDS YP_001032366.1 125623883 4796866 1015186..1016259 1 NC_009004.1 hypothetical protein 1016259 4796866 llmg_1052 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032366.1 1015186 D 416870 CDS YP_001032367.1 125623884 4798052 1016260..1016466 1 NC_009004.1 hypothetical protein 1016466 4798052 llmg_1053 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032367.1 1016260 D 416870 CDS YP_001032368.1 125623885 4798058 1016490..1017032 1 NC_009004.1 Similar to ParB-like nucleases; hypothetical protein 1017032 4798058 llmg_1054 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032368.1 1016490 D 416870 CDS YP_001032369.1 125623886 4797825 1017062..1017364 1 NC_009004.1 Lambda repressor-like, DNA-binding; Conserved hypothetical protein; transcriptional regulator 1017364 4797825 llmg_1055 Lactococcus lactis subsp. cremoris MG1363 transcriptional regulator YP_001032369.1 1017062 D 416870 CDS YP_001032370.1 125623887 4797949 1017646..1018590 1 NC_009004.1 CDF: cation diffusion facilitator family transporter; Conserved hypothetical protein; cation transporter 1018590 4797949 llmg_1056 Lactococcus lactis subsp. cremoris MG1363 cation transporter YP_001032370.1 1017646 D 416870 CDS YP_001032371.1 125623888 4798248 1018644..1019075 1 NC_009004.1 Phosphate-starvation-inducible E; Specificity unclear; phosphate-starvation-inducible protein PsiE 1019075 4798248 llmg_1057 Lactococcus lactis subsp. cremoris MG1363 phosphate-starvation-inducible protein PsiE YP_001032371.1 1018644 D 416870 CDS YP_001032372.1 125623889 4798460 complement(1019146..1020066) 1 NC_009004.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 1020066 coaA 4798460 coaA Lactococcus lactis subsp. cremoris MG1363 pantothenate kinase YP_001032372.1 1019146 R 416870 CDS YP_001032373.1 125623890 4797903 1020255..1020851 1 NC_009004.1 High confidence in function and specificity; ribosomal RNA small subunit methyltransferase C 1020851 rsmC 4797903 rsmC Lactococcus lactis subsp. cremoris MG1363 ribosomal RNA small subunit methyltransferase C YP_001032373.1 1020255 D 416870 CDS YP_001032374.1 125623891 4798397 1020886..1022178 1 NC_009004.1 Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway; pyrimidine-nucleoside phosphorylase 1022178 pdp 4798397 pdp Lactococcus lactis subsp. cremoris MG1363 pyrimidine-nucleoside phosphorylase YP_001032374.1 1020886 D 416870 CDS YP_001032375.1 125623892 4798125 1022180..1022368 1 NC_009004.1 hypothetical protein 1022368 4798125 llmg_1061 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032375.1 1022180 D 416870 CDS YP_001032376.1 125623893 4798303 1022381..1023043 1 NC_009004.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 1023043 deoC 4798303 deoC Lactococcus lactis subsp. cremoris MG1363 deoxyribose-phosphate aldolase YP_001032376.1 1022381 D 416870 CDS YP_001032377.1 125623894 4798883 1023030..1023422 1 NC_009004.1 High confidence in function and specificity; Cdd protein 1023422 cdd 4798883 cdd Lactococcus lactis subsp. cremoris MG1363 Cdd protein YP_001032377.1 1023030 D 416870 CDS YP_001032378.1 125623895 4796662 1023690..1024745 1 NC_009004.1 Conserved hypothetical protein; basic membrane protein A 1024745 bmpA 4796662 bmpA Lactococcus lactis subsp. cremoris MG1363 basic membrane protein A YP_001032378.1 1023690 D 416870 CDS YP_001032379.1 125623896 4798861 1024931..1025638 1 NC_009004.1 High confidence in function and specificity; GntR family transcriptional regulator 1025638 rgrB 4798861 rgrB Lactococcus lactis subsp. cremoris MG1363 GntR family transcriptional regulator YP_001032379.1 1024931 D 416870 CDS YP_001032380.1 125623897 4797136 complement(1025646..1026086) 1 NC_009004.1 hypothetical protein 1026086 4797136 llmg_1066 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032380.1 1025646 R 416870 CDS YP_001032381.1 125623898 4797348 complement(1026184..1027737) 1 NC_009004.1 High confidence in function and specificity; sensor protein kinase kinB 1027737 kinB 4797348 kinB Lactococcus lactis subsp. cremoris MG1363 sensor protein kinase kinB YP_001032381.1 1026184 R 416870 CDS YP_001032382.1 125623899 4796646 complement(1027727..1028437) 1 NC_009004.1 Response regulator receiver domain; High confidence in function and specificity; two-component system regulator llrB 1028437 llrB 4796646 llrB Lactococcus lactis subsp. cremoris MG1363 two-component system regulator llrB YP_001032382.1 1027727 R 416870 CDS YP_001032383.1 125623900 4796668 1028621..1028956 1 NC_009004.1 PF04297: helix-turn-helix protein, YlxM/p13-like; DNA-binding protein 1028956 4796668 llmg_1069 Lactococcus lactis subsp. cremoris MG1363 DNA-binding protein YP_001032383.1 1028621 D 416870 CDS YP_001032384.1 125623901 4797308 1029743..1030273 1 NC_009004.1 Similar to prophage gene p301 from L.lactis IL1403; Conserved hypothetical protein; hypothetical protein 1030273 4797308 llmg_1070 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032384.1 1029743 D 416870 CDS YP_001032385.1 125623902 4797300 1030384..1030953 1 NC_009004.1 High confidence in function and specificity; hypothetical protein 1030953 4797300 llmg_1071 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032385.1 1030384 D 416870 CDS YP_001032386.1 125623903 4797052 1031842..1032132 1 NC_009004.1 transposase helper protein for IS904; hypothetical protein 1032132 4797052 llmg_1072 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032386.1 1031842 D 416870 CDS YP_001032387.1 125623904 4797256 1032228..1032944 1 NC_009004.1 Integrase, catalytic region, 30 aa from the C- terminus are missing, possibly inactive; High confidence in function and specificity; transposase for insertion sequence element IS904E (fragment) 1032944 4797256 llmg_1073 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS904E (fragment) YP_001032387.1 1032228 D 416870 CDS YP_001032388.1 125623905 4797245 complement(1032985..1033743) 1 NC_009004.1 PF01695: IstB-like ATP-binding protein; Conserved hypothetical protein; transposase helper protein for IS712E 1033743 4797245 llmg_1074 Lactococcus lactis subsp. cremoris MG1363 transposase helper protein for IS712E YP_001032388.1 1032985 R 416870 CDS YP_001032389.1 125623906 4798427 complement(1033755..1034978) 1 NC_009004.1 Integrase, catalytic region; Specificity unclear; transposase for insertion sequence element IS712E 1034978 tnp712 4798427 tnp712 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS712E YP_001032389.1 1033755 R 416870 CDS YP_001032390.1 125623907 4797535 complement(1035285..1035836) 1 NC_009004.1 GCN5-related N-acetyltransferase; Family membership; acetyltransferase 1035836 4797535 llmg_1076 Lactococcus lactis subsp. cremoris MG1363 acetyltransferase YP_001032390.1 1035285 R 416870 CDS YP_001032391.1 125623908 4798468 1036203..1036625 1 NC_009004.1 Family membership; glyoxalase 1036625 4798468 llmg_1077 Lactococcus lactis subsp. cremoris MG1363 glyoxalase YP_001032391.1 1036203 D 416870 CDS YP_001032392.1 125623909 4798274 1036771..1037319 1 NC_009004.1 hypothetical protein 1037319 4798274 llmg_1078 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032392.1 1036771 D 416870 CDS YP_001032393.1 125623910 4799020 complement(1037518..1037865) 1 NC_009004.1 Protein of unknown function DUF1093; hypothetical protein 1037865 4799020 llmg_1079 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032393.1 1037518 R 416870 CDS YP_001032394.1 125623911 4796788 1038050..1038478 1 NC_009004.1 Specificity unclear; universal stress protein A2 1038478 uspA2 4796788 uspA2 Lactococcus lactis subsp. cremoris MG1363 universal stress protein A2 YP_001032394.1 1038050 D 416870 CDS YP_001032395.1 125623912 4797343 1038629..1038982 1 NC_009004.1 Protein of unknown function DUF1304; Conserved hypothetical protein; hypothetical protein 1038982 4797343 llmg_1081 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032395.1 1038629 D 416870 CDS YP_001032396.1 125623913 4797554 complement(1039099..1039854) 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 1039854 4797554 llmg_1082 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032396.1 1039099 R 416870 CDS YP_001032397.1 125623914 4797591 complement(1040025..1040579) 1 NC_009004.1 Protein of unknown function DUF1211; Conserved hypothetical protein; hypothetical protein 1040579 4797591 llmg_1083 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032397.1 1040025 R 416870 CDS YP_001032398.1 125623915 4799107 1040836..1041405 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 1041405 4799107 llmg_1084 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032398.1 1040836 D 416870 CDS YP_001032399.1 125623916 4799149 1041625..1042350 1 NC_009004.1 Protein of unknown function DUF208; hypothetical protein 1042350 4799149 llmg_1085 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032399.1 1041625 D 416870 CDS YP_001032400.1 125623917 4799146 1042609..1045242 1 NC_009004.1 Specificity unclear; cation (calcium) transporting ATPase 1045242 4799146 llmg_1086 Lactococcus lactis subsp. cremoris MG1363 cation (calcium) transporting ATPase YP_001032400.1 1042609 D 416870 CDS YP_001032401.1 125623918 4799143 complement(1045285..1045914) 1 NC_009004.1 High confidence in function and specificity; N-acetylglucosaminidase 1045914 acmC 4799143 acmC Lactococcus lactis subsp. cremoris MG1363 N-acetylglucosaminidase YP_001032401.1 1045285 R 416870 CDS YP_001032402.1 125623919 4798879 1046138..1046611 1 NC_009004.1 High confidence in function and specificity; gluthatione peroxidase 1046611 gpo 4798879 gpo Lactococcus lactis subsp. cremoris MG1363 gluthatione peroxidase YP_001032402.1 1046138 D 416870 CDS YP_001032403.1 125623920 4798610 1046961..1050155 1 NC_009004.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 1050155 carB 4798610 carB Lactococcus lactis subsp. cremoris MG1363 carbamoyl phosphate synthase large subunit YP_001032403.1 1046961 D 416870 CDS YP_001032404.1 125623921 4798932 1050354..1050935 1 NC_009004.1 hypothetical protein 1050935 4798932 llmg_1090 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032404.1 1050354 D 416870 CDS YP_001032405.1 125623922 4798928 1051013..1051231 1 NC_009004.1 hypothetical protein 1051231 4798928 llmg_1091 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032405.1 1051013 D 416870 CDS YP_001032406.1 125623923 4798624 1051383..1052867 1 NC_009004.1 hypothetical protein 1052867 4798624 llmg_1092 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032406.1 1051383 D 416870 CDS YP_001032407.1 125623924 4798631 1052879..1053883 1 NC_009004.1 Bacterial protein of unknown function DUF916; Conserved hypothetical protein; hypothetical protein 1053883 4798631 llmg_1093 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032407.1 1052879 D 416870 CDS YP_001032408.1 125623925 4798647 1053915..1054247 1 NC_009004.1 hypothetical protein 1054247 4798647 llmg_1094 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032408.1 1053915 D 416870 CDS YP_001032409.1 125623926 4798652 1054301..1055044 1 NC_009004.1 hypothetical protein 1055044 4798652 llmg_1095 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032409.1 1054301 D 416870 CDS YP_001032410.1 125623927 4798636 1055122..1056285 1 NC_009004.1 Bacterial protein of unknown function DUF916; hypothetical protein 1056285 4798636 llmg_1096 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032410.1 1055122 D 416870 CDS YP_001032411.1 125623928 4798644 complement(1056343..1057071) 1 NC_009004.1 High confidence in function and specificity; glycerol uptake facilitator 1057071 glpF2 4798644 glpF2 Lactococcus lactis subsp. cremoris MG1363 glycerol uptake facilitator YP_001032411.1 1056343 R 416870 CDS YP_001032412.1 125623929 4798028 complement(1057090..1058667) 1 NC_009004.1 High confidence in function and specificity; GlpD protein 1058667 glpD 4798028 glpD Lactococcus lactis subsp. cremoris MG1363 GlpD protein YP_001032412.1 1057090 R 416870 CDS YP_001032413.1 125623930 4798474 complement(1058720..1060237) 1 NC_009004.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 1060237 glpK 4798474 glpK Lactococcus lactis subsp. cremoris MG1363 glycerol kinase YP_001032413.1 1058720 R 416870 CDS YP_001032414.1 125623931 4798342 1060537..1061070 1 NC_009004.1 High confidence in function and specificity; ribosomal large subunit pseudouridine synthase 1061070 rluC 4798342 rluC Lactococcus lactis subsp. cremoris MG1363 ribosomal large subunit pseudouridine synthase YP_001032414.1 1060537 D 416870 CDS YP_001032415.1 125623932 4797579 complement(1061106..1061891) 1 NC_009004.1 Protein of unknown function DUF477; Conserved hypothetical protein; hypothetical protein 1061891 4797579 llmg_1101 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032415.1 1061106 R 416870 CDS YP_001032416.1 125623933 4798621 complement(1061888..1063039) 1 NC_009004.1 hypothetical protein 1063039 4798621 llmg_1102 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032416.1 1061888 R 416870 CDS YP_001032417.1 125623934 4796789 complement(1063253..1064464) 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 1064464 4796789 llmg_1103 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032417.1 1063253 R 416870 CDS YP_001032418.1 125623935 4798113 1064841..1066205 1 NC_009004.1 Family membership; drug-export protein 1066205 4798113 llmg_1104 Lactococcus lactis subsp. cremoris MG1363 drug-export protein YP_001032418.1 1064841 D 416870 CDS YP_001032419.1 125623936 4797217 1066455..1067243 1 NC_009004.1 Phthalate dioxygenase reductase; High confidence in function and specificity; dihydroorotate dehydrogenase, electron transfer subunit 1067243 pyrK 4797217 pyrK Lactococcus lactis subsp. cremoris MG1363 dihydroorotate dehydrogenase, electron transfer subunit YP_001032419.1 1066455 D 416870 CDS YP_001032420.1 125623937 4798332 1067401..1068336 1 NC_009004.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits, similar to the PyrDA subunits and two PyrK subunits; dihydroorotate dehydrogenase 1B 1068336 pyrDB 4798332 pyrDB Lactococcus lactis subsp. cremoris MG1363 dihydroorotate dehydrogenase 1B YP_001032420.1 1067401 D 416870 CDS YP_001032421.1 125623938 4797639 1068466..1069179 1 NC_009004.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1069179 pyrF 4797639 pyrF Lactococcus lactis subsp. cremoris MG1363 orotidine 5'-phosphate decarboxylase YP_001032421.1 1068466 D 416870 CDS YP_001032422.1 125623939 4797373 1069181..1069639 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 1069639 4797373 llmg_1108 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032422.1 1069181 D 416870 CDS YP_001032423.1 125623940 4798276 complement(1069648..1070364) 1 NC_009004.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 1070364 gidB 4798276 gidB Lactococcus lactis subsp. cremoris MG1363 16S rRNA methyltransferase GidB YP_001032423.1 1069648 R 416870 CDS YP_001032424.1 125623941 4798489 complement(1070361..1071320) 1 NC_009004.1 High confidence in function and specificity; heptaprenyl diphosphate synthase component II 1071320 ispB 4798489 ispB Lactococcus lactis subsp. cremoris MG1363 heptaprenyl diphosphate synthase component II YP_001032424.1 1070361 R 416870 CDS YP_001032425.1 125623942 4797725 complement(1071311..1071841) 1 NC_009004.1 High confidence in function and specificity; heptaprenyl diphosphate synthase component I 1071841 gerCA 4797725 gerCA Lactococcus lactis subsp. cremoris MG1363 heptaprenyl diphosphate synthase component I YP_001032425.1 1071311 R 416870 CDS YP_001032426.1 125623943 4799103 complement(1071838..1072245) 1 NC_009004.1 Protein of unknown function DUF1312; hypothetical protein 1072245 4799103 llmg_1112 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032426.1 1071838 R 416870 CDS YP_001032427.1 125623944 4798258 complement(1072316..1073257) 1 NC_009004.1 High confidence in function and specificity; UDP--glucose-1-phosphate uridylyltransferase 1073257 galU 4798258 galU Lactococcus lactis subsp. cremoris MG1363 UDP--glucose-1-phosphate uridylyltransferase YP_001032427.1 1072316 R 416870 CDS YP_001032428.1 125623945 4797670 complement(1073311..1074339) 1 NC_009004.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 1074339 gpsA 4797670 gpsA Lactococcus lactis subsp. cremoris MG1363 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_001032428.1 1073311 R 416870 CDS YP_001032429.1 125623946 4798613 1074531..1075157 1 NC_009004.1 Similar to Bacillus subtilis xpaC gene, involved in cell morphology; Specificity unclear; XpaC-like protein 1075157 4798613 llmg_1115 Lactococcus lactis subsp. cremoris MG1363 XpaC-like protein YP_001032429.1 1074531 D 416870 CDS YP_001032430.1 125623947 4797228 1075298..1076476 1 NC_009004.1 High confidence in function and specificity; toxic anion resistance protein 1076476 telA1 4797228 telA1 Lactococcus lactis subsp. cremoris MG1363 toxic anion resistance protein YP_001032430.1 1075298 D 416870 CDS YP_001032431.1 125623948 4798217 1076647..1077795 1 NC_009004.1 High confidence in function and specificity; NagA protein 1077795 nagA 4798217 nagA Lactococcus lactis subsp. cremoris MG1363 NagA protein YP_001032431.1 1076647 D 416870 CDS YP_001032432.1 125623949 4798168 1078182..1079204 1 NC_009004.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 1079204 pfk 4798168 pfk Lactococcus lactis subsp. cremoris MG1363 6-phosphofructokinase YP_001032432.1 1078182 D 416870 CDS YP_001032433.1 125623950 4797791 1079292..1080800 1 NC_009004.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1080800 pyk 4797791 pyk Lactococcus lactis subsp. cremoris MG1363 pyruvate kinase YP_001032433.1 1079292 D 416870 CDS YP_001032434.1 125623951 4797727 1080918..1081895 1 NC_009004.1 Converts (S)-lactate and NAD(+) to pyruvate and NADH; L-lactate dehydrogenase 1081895 ldh 4797727 ldh Lactococcus lactis subsp. cremoris MG1363 L-lactate dehydrogenase YP_001032434.1 1080918 D 416870 CDS YP_001032435.1 125623952 4797718 complement(1082012..1082965) 1 NC_009004.1 High confidence in function and specificity; purine/cytidine ABC transporter permease 1082965 nupC 4797718 nupC Lactococcus lactis subsp. cremoris MG1363 purine/cytidine ABC transporter permease YP_001032435.1 1082012 R 416870 CDS YP_001032436.1 125623953 4797975 complement(1082962..1084056) 1 NC_009004.1 High confidence in function and specificity; purine/cytidine ABC transporter permease 1084056 nupB 4797975 nupB Lactococcus lactis subsp. cremoris MG1363 purine/cytidine ABC transporter permease YP_001032436.1 1082962 R 416870 CDS YP_001032437.1 125623954 4797583 complement(1084049..1085569) 1 NC_009004.1 High confidence in function and specificity; purine/cytidine ABC transporter ATP-binding protein 1085569 nupA 4797583 nupA Lactococcus lactis subsp. cremoris MG1363 purine/cytidine ABC transporter ATP-binding protein YP_001032437.1 1084049 R 416870 CDS YP_001032438.1 125623955 4798349 complement(1085751..1086566) 1 NC_009004.1 Similar to rRNA (guanine-N1-)-methyltransferase; Family membership; hypothetical protein 1086566 4798349 llmg_1124 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032438.1 1085751 R 416870 CDS YP_001032439.1 125623956 4797227 complement(1086608..1088230) 1 NC_009004.1 Family membership; fibronectin-binding protein-like protein A 1088230 fbpA 4797227 fbpA Lactococcus lactis subsp. cremoris MG1363 fibronectin-binding protein-like protein A YP_001032439.1 1086608 R 416870 CDS YP_001032440.1 125623957 4799134 1088535..1088978 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 1088978 4799134 llmg_1126 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032440.1 1088535 D 416870 CDS YP_001032441.1 125623958 4797200 1089321..1093370 1 NC_009004.1 Carboxypeptidase regulatory region; Conserved hypothetical protein; cell wall surface anchor family protein 1093370 4797200 llmg_1127 Lactococcus lactis subsp. cremoris MG1363 cell wall surface anchor family protein YP_001032441.1 1089321 D 416870 CDS YP_001032442.1 125623959 4798518 1093388..1093633 1 NC_009004.1 Carboxypeptidase regulatory region; hypothetical protein 1093633 4798518 llmg_1128 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032442.1 1093388 D 416870 CDS YP_001032443.1 125623960 4798269 1093651..1094226 1 NC_009004.1 Surface protein from Gram-positive cocci, anchor region; cell wall surface anchor family protein 1094226 4798269 llmg_1129 Lactococcus lactis subsp. cremoris MG1363 cell wall surface anchor family protein YP_001032443.1 1093651 D 416870 CDS YP_001032444.1 125623961 4797792 1094974..1095348 1 NC_009004.1 Arsenate reductase and related, Similar to regulatory protein spx; hypothetical protein 1095348 4797792 llmg_1130 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032444.1 1094974 D 416870 CDS YP_001032445.1 125623962 4797211 1095546..1096484 1 NC_009004.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase 1096484 panE 4797211 panE Lactococcus lactis subsp. cremoris MG1363 2-dehydropantoate 2-reductase YP_001032445.1 1095546 D 416870 CDS YP_001032446.1 125623963 4799072 1096630..1097802 1 NC_009004.1 TIGR00619: nuclease SbcCD, D subunit; High confidence in function and specificity; nuclease SbcCD subunit D 1097802 sbcD 4799072 sbcD Lactococcus lactis subsp. cremoris MG1363 nuclease SbcCD subunit D YP_001032446.1 1096630 D 416870 CDS YP_001032447.1 125623964 4799145 1097805..1100945 1 NC_009004.1 ATP-dependent dsDNA exonuclease; High confidence in function and specificity; nuclease sbcCD subunit C 1100945 sbcC 4799145 sbcC Lactococcus lactis subsp. cremoris MG1363 nuclease sbcCD subunit C YP_001032447.1 1097805 D 416870 CDS YP_001032448.1 125623965 4797721 1101195..1101425 1 NC_009004.1 hypothetical protein 1101425 4797721 llmg_1134 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032448.1 1101195 D 416870 CDS YP_001032449.1 125623966 4798724 complement(1101504..1101917) 1 NC_009004.1 hypothetical protein 1101917 4798724 llmg_1135 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032449.1 1101504 R 416870 CDS YP_001032450.1 125623967 4798268 1102206..1102919 1 NC_009004.1 PF00005: ABC transporter TIGR01166: cobalt transport protein ATP-binding subunit; High confidence in function and specificity; manganese ABC transporter ATP binding protein 1102919 mtsB 4798268 mtsB Lactococcus lactis subsp. cremoris MG1363 manganese ABC transporter ATP binding protein YP_001032450.1 1102206 D 416870 CDS YP_001032451.1 125623968 4797517 1102926..1103765 1 NC_009004.1 PF00950: ABC 3 transport family; Conserved hypothetical protein; manganese transport system membrane protein 1103765 mtsC 4797517 mtsC Lactococcus lactis subsp. cremoris MG1363 manganese transport system membrane protein YP_001032451.1 1102926 D 416870 CDS YP_001032452.1 125623969 4797486 1103765..1104712 1 NC_009004.1 PF01297: Periplasmic solute binding protein family; Family membership; manganese ABC transporter substrate binding protein 1104712 mtsA 4797486 mtsA Lactococcus lactis subsp. cremoris MG1363 manganese ABC transporter substrate binding protein YP_001032452.1 1103765 D 416870 CDS YP_001032453.1 125623970 4797513 1105019..1105885 1 NC_009004.1 hypothetical protein 1105885 4797513 llmg_1139 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032453.1 1105019 D 416870 CDS YP_001032454.1 125623971 4797235 1105938..1107194 1 NC_009004.1 hypothetical protein 1107194 4797235 llmg_1140 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032454.1 1105938 D 416870 CDS YP_001032455.1 125623972 4797204 1107609..1107932 1 NC_009004.1 contains HTH domain; Conserved hypothetical protein; transcriptional regulator 1107932 4797204 llmg_1141 Lactococcus lactis subsp. cremoris MG1363 transcriptional regulator YP_001032455.1 1107609 D 416870 CDS YP_001032456.1 125623973 4797805 complement(1108260..1109435) 1 NC_009004.1 High confidence in function and specificity; transposase for insertion sequence element IS905F 1109435 tnp905 4797805 tnp905 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS905F YP_001032456.1 1108260 R 416870 CDS YP_001032457.1 125623974 4798044 1109730..1110245 1 NC_009004.1 inactivated by IS981, HTH-type transcriptional regulator, PF01381: Helix-turn-helix; hypothetical protein 1110245 4798044 llmg_1143 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032457.1 1109730 D 416870 CDS YP_001032458.1 125623975 4797798 complement(1110256..1111095) 1 NC_009004.1 High confidence in function and specificity; transposase for insertion sequence element IS981I 1111095 tnp981 4797798 tnp981 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS981I YP_001032458.1 1110256 R 416870 CDS YP_001032459.1 125623976 4797277 complement(1111107..1111367) 1 NC_009004.1 transposase helper protein for IS981; hypothetical protein 1111367 4797277 llmg_1145 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032459.1 1111107 R 416870 CDS YP_001032460.1 125623977 4798263 1111431..1111781 1 NC_009004.1 inactivated by IS981, HTH-type transcriptional regulator; hypothetical protein 1111781 4798263 llmg_1146 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032460.1 1111431 D 416870 CDS YP_001032461.1 125623978 4797234 1113008..1113331 1 NC_009004.1 contains HTH domain; Conserved hypothetical protein; transcriptional regulator 1113331 4797234 llmg_1147 Lactococcus lactis subsp. cremoris MG1363 transcriptional regulator YP_001032461.1 1113008 D 416870 CDS YP_001032462.1 125623979 4797770 1113561..1115264 1 NC_009004.1 hypothetical protein 1115264 4797770 llmg_1148 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032462.1 1113561 D 416870 CDS YP_001032463.1 125623980 4797203 1115457..1116413 1 NC_009004.1 PF02423: Ornithine cyclodeaminase/mu-crystallin family; High confidence in function and specificity; ornithine cyclodeaminase, mu-crystallin-like protein 1116413 ocd 4797203 ocd Lactococcus lactis subsp. cremoris MG1363 ornithine cyclodeaminase, mu-crystallin-like protein YP_001032463.1 1115457 D 416870 CDS YP_001032464.1 125623981 4799095 1116424..1117206 1 NC_009004.1 phenazine biosynthesis protein, PF02567: Phenazine biosynthesis-like protein, TIGR00654: phenazine biosynthesis protein PhzF family; hypothetical protein 1117206 4799095 llmg_1150 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032464.1 1116424 D 416870 CDS YP_001032465.1 125623982 4797199 complement(1117267..1118679) 1 NC_009004.1 transcriptional regulator, PF00392: Bacterial regulatory proteins, GntR family; hypothetical protein 1118679 4797199 llmg_1151 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032465.1 1117267 R 416870 CDS YP_001032466.1 125623983 4797371 1119320..1120990 1 NC_009004.1 PF07523: Bacterial Ig-like domain (group 3); hypothetical protein 1120990 4797371 llmg_1152 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032466.1 1119320 D 416870 CDS YP_001032467.1 125623984 4797363 1121415..1121996 1 NC_009004.1 PF00117: Glutamine amidotransferase class-I, TIGR00566: glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase; High confidence in function and specificity; p-aminobenzoate synthetase, component II 1121996 pabA 4797363 pabA Lactococcus lactis subsp. cremoris MG1363 p-aminobenzoate synthetase, component II YP_001032467.1 1121415 D 416870 CDS YP_001032468.1 125623985 4799079 1122001..1123887 1 NC_009004.1 PF00425: chorismate binding enzyme, TIGR00553: para- aminobenzoate synthase, component I; High confidence in function and specificity; para-aminobenzoate synthase component I 1123887 pabB 4799079 pabB Lactococcus lactis subsp. cremoris MG1363 para-aminobenzoate synthase component I YP_001032468.1 1122001 D 416870 CDS YP_001032469.1 125623986 4799078 1124076..1124447 1 NC_009004.1 potential redox protein; structural similarity to proteins involved in arsenate reduction in the oxydoreduction reaction, Arsenate reductase and related, PF03960: ArsC family; Conserved hypothetical protein; Spx-like protein 1124447 4799078 llmg_1155 Lactococcus lactis subsp. cremoris MG1363 Spx-like protein YP_001032469.1 1124076 D 416870 CDS YP_001032470.1 125623987 4798447 1124506..1124832 1 NC_009004.1 repressor of arsenical resistance, PF06953: Arsenical resistance operon trans-acting repressor ArsD; hypothetical protein 1124832 4798447 llmg_1156 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032470.1 1124506 D 416870 CDS YP_001032471.1 125623988 4797964 complement(1124929..1125093) 1 NC_009004.1 Pseudogene; hypothetical protein 1125093 4797964 llmg_1158 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032471.1 1124929 R 416870 CDS YP_001032472.1 125623989 4796849 complement(1125090..1125452) 1 NC_009004.1 Pseudogene; hypothetical protein 1125452 4796849 llmg_1159 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032472.1 1125090 R 416870 CDS YP_001032473.1 125623990 4797577 1125608..1126618 1 NC_009004.1 hypothetical protein 1126618 4797577 llmg_1160 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032473.1 1125608 D 416870 CDS YP_001032474.1 125623991 4799144 1126850..1127323 1 NC_009004.1 Pseudogene; Conserved hypothetical protein; sialic acid-specific 9-O-acetylesterase 1127323 4799144 llmg_1161 Lactococcus lactis subsp. cremoris MG1363 sialic acid-specific 9-O-acetylesterase YP_001032474.1 1126850 D 416870 CDS YP_001032475.1 125623992 4799054 1127360..1128718 1 NC_009004.1 Pseudogene; Conserved hypothetical protein; sialic acid-specific 9-O-acetylesterase 1128718 4799054 llmg_1162 Lactococcus lactis subsp. cremoris MG1363 sialic acid-specific 9-O-acetylesterase YP_001032475.1 1127360 D 416870 CDS YP_001032476.1 125623993 4798935 1128720..1130027 1 NC_009004.1 IPR006059: Bacterial extracellular solute-binding protein, family 1; Conserved hypothetical protein; sugar ABC transporter substrate-binding protein 1130027 4798935 llmg_1163 Lactococcus lactis subsp. cremoris MG1363 sugar ABC transporter substrate-binding protein YP_001032476.1 1128720 D 416870 CDS YP_001032477.1 125623994 4798931 1130161..1131120 1 NC_009004.1 sugar ABC transporter permease, IPR000515: Binding-protein-dependent transport systems inner membrane component; Conserved hypothetical protein; hypothetical protein 1131120 4798931 llmg_1164 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032477.1 1130161 D 416870 CDS YP_001032478.1 125623995 4798282 1131120..1131974 1 NC_009004.1 sugar ABC transporter permease, PF00528: Binding-protein-dependent transport system inner membrane component; Conserved hypothetical protein; hypothetical protein 1131974 4798282 llmg_1165 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032478.1 1131120 D 416870 CDS YP_001032479.1 125623996 4798270 1131976..1132872 1 NC_009004.1 pseudogene, IPR008928: Glycoside transferase, six- hairpin; High confidence in function and specificity; endoglucanase 1132872 4798270 llmg_1166 Lactococcus lactis subsp. cremoris MG1363 endoglucanase YP_001032479.1 1131976 D 416870 CDS YP_001032480.1 125623997 4797239 1132978..1133109 1 NC_009004.1 pseudogene, IPR008928: Glycoside transferase, six- hairpin; Conserved hypothetical protein; endoglucanase 1133109 4797239 llmg_1167 Lactococcus lactis subsp. cremoris MG1363 endoglucanase YP_001032480.1 1132978 D 416870 CDS YP_001032481.1 125623998 4797236 1133124..1133750 1 NC_009004.1 PF01522: Polysaccharide deacetylase; High confidence in function and specificity; polysaccharide deacetylase 1133750 4797236 llmg_1168 Lactococcus lactis subsp. cremoris MG1363 polysaccharide deacetylase YP_001032481.1 1133124 D 416870 CDS YP_001032482.1 125623999 4797216 1133781..1135775 1 NC_009004.1 PF07488: Glycosyl hydrolase 67 middle domain, PF07477: Glycosyl hydrolase 67 C-terminus; High confidence in function and specificity; AguA protein 1135775 aguA 4797216 aguA Lactococcus lactis subsp. cremoris MG1363 AguA protein YP_001032482.1 1133781 D 416870 CDS YP_001032483.1 125624000 4797474 1135978..1137705 1 NC_009004.1 IPR004843: Metallophosphoesterase; hypothetical protein 1137705 4797474 llmg_1170 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032483.1 1135978 D 416870 CDS YP_001032484.1 125624001 4797212 complement(1137774..1139159) 1 NC_009004.1 hypothetical protein 1139159 4797212 llmg_1171 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032484.1 1137774 R 416870 CDS YP_001032485.1 125624002 4796858 complement(1139152..1139913) 1 NC_009004.1 PF00455: Bacterial regulatory proteins, deoR family; Conserved hypothetical protein; transcriptional regulator 1139913 rdrB 4796858 rdrB Lactococcus lactis subsp. cremoris MG1363 transcriptional regulator YP_001032485.1 1139152 R 416870 CDS YP_001032486.1 125624003 4796740 1140260..1141309 1 NC_009004.1 membrane protein; hypothetical protein 1141309 4796740 llmg_1173 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032486.1 1140260 D 416870 CDS YP_001032487.1 125624004 4798406 1141470..1142015 1 NC_009004.1 hypothetical protein 1142015 4798406 llmg_1174 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032487.1 1141470 D 416870 CDS YP_001032488.1 125624005 4797779 1142245..1143093 1 NC_009004.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc); ribosomal biogenesis GTPase 1143093 rbgA 4797779 rbgA Lactococcus lactis subsp. cremoris MG1363 ribosomal biogenesis GTPase YP_001032488.1 1142245 D 416870 CDS YP_001032489.1 125624006 4797799 1143206..1143979 1 NC_009004.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 1143979 rnhB 4797799 rnhB Lactococcus lactis subsp. cremoris MG1363 ribonuclease HII YP_001032489.1 1143206 D 416870 CDS YP_001032490.1 125624007 4797311 1144571..1145401 1 NC_009004.1 activates chloride dependent transcription of gadCB, TIGR01716: Transcriptional activator Rgg/GadR/MutR, C-terminal domain; High confidence in function and specificity; positive regulator GadR 1145401 gadR 4797311 gadR Lactococcus lactis subsp. cremoris MG1363 positive regulator GadR YP_001032490.1 1144571 D 416870 CDS YP_001032491.1 125624008 4798793 1145542..1147056 1 NC_009004.1 TIGR00910: Glutamate:g-aminobutyrate antiporter, involved in glutamate-dependent acid resistance; High confidence in function and specificity; glutamate/gamma-aminobutyrate antiporter 1147056 gadC 4798793 gadC Lactococcus lactis subsp. cremoris MG1363 glutamate/gamma-aminobutyrate antiporter YP_001032491.1 1145542 D 416870 CDS YP_001032492.1 125624009 4797573 1147076..1148476 1 NC_009004.1 PF00282: Pyridoxal-dependent decarboxylase conserved domain, TIGR01788: glutamate decarboxylase, involved in glutamate-dependant acid resistance; High confidence in function and specificity; glutamate decarboxylase 1148476 gadB 4797573 gadB Lactococcus lactis subsp. cremoris MG1363 glutamate decarboxylase YP_001032492.1 1147076 D 416870 CDS YP_001032493.1 125624010 4798359 complement(1148551..1149297) 1 NC_009004.1 mechanosensitive ion channel, PF00924: Mechanosensitive ion channel; hypothetical protein 1149297 4798359 llmg_1180 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032493.1 1148551 R 416870 CDS YP_001032494.1 125624011 4798630 1149457..1150479 1 NC_009004.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 1150479 ilvE 4798630 ilvE Lactococcus lactis subsp. cremoris MG1363 branched-chain amino acid aminotransferase YP_001032494.1 1149457 D 416870 CDS YP_001032495.1 125624012 4797699 complement(1150512..1151123) 1 NC_009004.1 IPR011004: Trimeric LpxA-like; Conserved hypothetical protein; acetyltransferase 1151123 4797699 llmg_1182 Lactococcus lactis subsp. cremoris MG1363 acetyltransferase YP_001032495.1 1150512 R 416870 CDS YP_001032496.1 125624013 4798639 1151292..1155761 1 NC_009004.1 PF01645: Conserved region in glutamate synthase; High confidence in function and specificity; glutamate synthase, large subunit 1155761 gltB 4798639 gltB Lactococcus lactis subsp. cremoris MG1363 glutamate synthase, large subunit YP_001032496.1 1151292 D 416870 CDS YP_001032497.1 125624014 4796775 1155761..1157200 1 NC_009004.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 1157200 gltD 4796775 gltD Lactococcus lactis subsp. cremoris MG1363 glutamate synthase subunit beta YP_001032497.1 1155761 D 416870 CDS YP_001032498.1 125624015 4799015 1157315..1158574 1 NC_009004.1 PF00278: Pyridoxal-dependent decarboxylase, C- terminal sheet domain, TIGR01048: diaminopimelate decarboxylase; High confidence in function and specificity; LysA protein 1158574 lysA 4799015 lysA Lactococcus lactis subsp. cremoris MG1363 LysA protein YP_001032498.1 1157315 D 416870 CDS YP_001032499.1 125624016 4797083 1158725..1158964 1 NC_009004.1 PF03672: Protein of unknown function UPF0154; hypothetical protein 1158964 4797083 llmg_1186 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032499.1 1158725 D 416870 CDS YP_001032500.1 125624017 4796830 1159140..1159955 1 NC_009004.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 1159955 murI 4796830 murI Lactococcus lactis subsp. cremoris MG1363 glutamate racemase YP_001032500.1 1159140 D 416870 CDS YP_001032501.1 125624018 4797531 1159956..1160561 1 NC_009004.1 Ham1-like protein, PF01725: Ham1 family, TIGR00042: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; High confidence in function and specificity; hypothetical protein 1160561 4797531 llmg_1188 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032501.1 1159956 D 416870 CDS YP_001032502.1 125624019 4797720 1160600..1161103 1 NC_009004.1 TIGR00040: phosphodiesterase, MJ0936 family, PF00149: Calcineurin-like phosphoesterase; hypothetical protein 1161103 4797720 llmg_1189 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032502.1 1160600 D 416870 CDS YP_001032503.1 125624020 4797359 1161134..1161595 1 NC_009004.1 PF00571: 2 CBS domains; hypothetical protein 1161595 4797359 llmg_1190 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032503.1 1161134 D 416870 CDS YP_001032504.1 125624021 4797962 1161573..1162289 1 NC_009004.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 1162289 xerD 4797962 xerD Lactococcus lactis subsp. cremoris MG1363 site-specific tyrosine recombinase XerD YP_001032504.1 1161573 D 416870 CDS YP_001032505.1 125624022 4797931 1162320..1163048 1 NC_009004.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB; segregation and condensation protein A 1163048 scpA 4797931 scpA Lactococcus lactis subsp. cremoris MG1363 segregation and condensation protein A YP_001032505.1 1162320 D 416870 CDS YP_001032506.1 125624023 4799068 1163041..1163607 1 NC_009004.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpA; forms a homodimer; segregation and condensation protein B 1163607 scpB 4799068 scpB Lactococcus lactis subsp. cremoris MG1363 segregation and condensation protein B YP_001032506.1 1163041 D 416870 CDS YP_001032507.1 125624024 4799069 1163540..1164313 1 NC_009004.1 PF00849: RNA pseudouridylate synthase; High confidence in function and specificity; pseudouridylate synthase 1164313 rluB 4799069 rluB Lactococcus lactis subsp. cremoris MG1363 pseudouridylate synthase YP_001032507.1 1163540 D 416870 CDS YP_001032508.1 125624025 4797377 1164663..1165283 1 NC_009004.1 membrane protein; hypothetical protein 1165283 4797377 llmg_1195 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032508.1 1164663 D 416870 CDS YP_001032509.1 125624026 4797196 1165594..1166181 1 NC_009004.1 secreted protein; hypothetical protein 1166181 4797196 llmg_1196 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032509.1 1165594 D 416870 CDS YP_001032510.1 125624027 4797716 1166235..1166825 1 NC_009004.1 membrane protein; hypothetical protein 1166825 4797716 llmg_1197 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032510.1 1166235 D 416870 CDS YP_001032511.1 125624028 4797151 1166862..1167350 1 NC_009004.1 secreted protein; hypothetical protein 1167350 4797151 llmg_1198 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032511.1 1166862 D 416870 CDS YP_001032512.1 125624029 4797857 1167469..1168296 1 NC_009004.1 hypothetical protein 1168296 4797857 llmg_1200 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032512.1 1167469 D 416870 CDS YP_001032513.1 125624030 4798192 1168384..1168731 1 NC_009004.1 Pseudogene; hypothetical protein 1168731 4798192 llmg_1201 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032513.1 1168384 D 416870 CDS YP_001032514.1 125624031 4798046 1168869..1170686 1 NC_009004.1 PF00005: ABC transporter TIGR02203: lipid A export ATP-binding/permease MsbA; Conserved hypothetical protein; ABC transporter ABC binding and permease 1170686 4798046 llmg_1202 Lactococcus lactis subsp. cremoris MG1363 ABC transporter ABC binding and permease YP_001032514.1 1168869 D 416870 CDS YP_001032515.1 125624032 4799120 1170670..1172454 1 NC_009004.1 PF00664: ABC transporter transmembrane region, PF00005: ABC transporter TIGR02203: lipid A export ATP- binding/permease MsbA; Conserved hypothetical protein; ABC transporter ABC binding and permease 1172454 4799120 llmg_1203 Lactococcus lactis subsp. cremoris MG1363 ABC transporter ABC binding and permease YP_001032515.1 1170670 D 416870 CDS YP_001032516.1 125624033 4799040 1172575..1173333 1 NC_009004.1 IPR011056: Peptidase S24 and S26, C-terminal region, PF01381: Helix-turn-helix; Conserved hypothetical protein; HTH-type transcriptional regulator HdiR 1173333 hdiR 4799040 hdiR Lactococcus lactis subsp. cremoris MG1363 HTH-type transcriptional regulator HdiR YP_001032516.1 1172575 D 416870 CDS YP_001032517.1 125624034 4797550 1173347..1173535 1 NC_009004.1 membrane protein; hypothetical protein 1173535 4797550 llmg_1205 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032517.1 1173347 D 416870 CDS YP_001032518.1 125624035 4797191 1175758..1176273 1 NC_009004.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 1176273 rplJ 4797191 rplJ Lactococcus lactis subsp. cremoris MG1363 50S ribosomal protein L10 YP_001032518.1 1175758 D 416870 CDS YP_001032519.1 125624036 4797926 1176343..1176708 1 NC_009004.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 1176708 rplL 4797926 rplL Lactococcus lactis subsp. cremoris MG1363 50S ribosomal protein L7/L12 YP_001032519.1 1176343 D 416870 CDS YP_001032520.1 125624037 4797914 1177158..1177541 1 NC_009004.1 PF01047: MarR family; Conserved hypothetical protein; MarR family transcriptional regulator 1177541 rmaX 4797914 rmaX Lactococcus lactis subsp. cremoris MG1363 MarR family transcriptional regulator YP_001032520.1 1177158 D 416870 CDS YP_001032521.1 125624038 4798047 1177542..1179101 1 NC_009004.1 PF07690: Major facilitator superfamily, TIGR00711: drug resistance transporter EmrB/QacA subfamily; Conserved hypothetical protein; multidrug resistance protein 1179101 4798047 llmg_1210 Lactococcus lactis subsp. cremoris MG1363 multidrug resistance protein YP_001032521.1 1177542 D 416870 CDS YP_001032522.1 125624039 4798177 1179098..1179934 1 NC_009004.1 hypothetical protein 1179934 4798177 llmg_1211 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032522.1 1179098 D 416870 CDS YP_001032523.1 125624040 4798563 1181520..1181846 1 NC_009004.1 pseudogene, glycosyl transferase; hypothetical protein 1181846 4798563 llmg_1214 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032523.1 1181520 D 416870 CDS YP_001032524.1 125624041 4798094 1181861..1183993 1 NC_009004.1 Pseudogene, glycosyl transferase, PF00535: glycosyl transferase, family 2; hypothetical protein 1183993 4798094 llmg_1215 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032524.1 1181861 D 416870 CDS YP_001032525.1 125624042 4798091 1184278..1185030 1 NC_009004.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 1185030 thiM 4798091 thiM Lactococcus lactis subsp. cremoris MG1363 hydroxyethylthiazole kinase YP_001032525.1 1184278 D 416870 CDS YP_001032526.1 125624043 4797608 1185043..1185843 1 NC_009004.1 TIGR00097 : phosphomethylpyrimidine kinase; High confidence in function and specificity; phosphomethylpyrimidine kinase 1185843 thiD1 4797608 thiD1 Lactococcus lactis subsp. cremoris MG1363 phosphomethylpyrimidine kinase YP_001032526.1 1185043 D 416870 CDS YP_001032527.1 125624044 4797017 1185836..1186492 1 NC_009004.1 PF02581: Thiamine monophosphate synthase/TENI, TIGR00693: thiamine-phosphate pyrophosphorylase; High confidence in function and specificity; thiamine-phosphate pyrophosphorylase 1186492 thiE 4797017 thiE Lactococcus lactis subsp. cremoris MG1363 thiamine-phosphate pyrophosphorylase YP_001032527.1 1185836 D 416870 CDS YP_001032528.1 125624045 4797046 1186831..1188330 1 NC_009004.1 transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 1 1188330 dltA 4797046 dltA Lactococcus lactis subsp. cremoris MG1363 D-alanine--poly(phosphoribitol) ligase subunit 1 YP_001032528.1 1186831 D 416870 CDS YP_001032529.1 125624046 4798915 1188330..1189553 1 NC_009004.1 PF03062: Membrane bound O-acyl transferase, MBOAT; Conserved hypothetical protein; protein dltB (basic membrane protein) (BMP) 1189553 dltB 4798915 dltB Lactococcus lactis subsp. cremoris MG1363 protein dltB (basic membrane protein) (BMP) YP_001032529.1 1188330 D 416870 CDS YP_001032530.1 125624047 4798918 1189589..1189828 1 NC_009004.1 D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 2 1189828 dltC 4798918 dltC Lactococcus lactis subsp. cremoris MG1363 D-alanine--poly(phosphoribitol) ligase subunit 2 YP_001032530.1 1189589 D 416870 CDS YP_001032531.1 125624048 4798924 1189818..1191104 1 NC_009004.1 PF04918: DltD central region; High confidence in function and specificity; D-alanine transfer protein DltD 1191104 dltD 4798924 dltD Lactococcus lactis subsp. cremoris MG1363 D-alanine transfer protein DltD YP_001032531.1 1189818 D 416870 CDS YP_001032532.1 125624049 4796803 1191579..1194311 1 NC_009004.1 PF00122: E1-E2 ATPase, PF00690: Cation transporter/ATPase, N-terminus; High confidence in function and specificity; cation-transporting P-ATPase 1194311 mgtA 4796803 mgtA Lactococcus lactis subsp. cremoris MG1363 cation-transporting P-ATPase YP_001032532.1 1191579 D 416870 CDS YP_001032533.1 125624050 4798916 1194404..1195057 1 NC_009004.1 PF01325: Iron dependent repressor, N-terminal DNA binding domain; Conserved hypothetical protein; transcriptional regulator 1195057 4798916 llmg_1224 Lactococcus lactis subsp. cremoris MG1363 transcriptional regulator YP_001032533.1 1194404 D 416870 CDS YP_001032534.1 125624051 4796963 1195217..1197490 1 NC_009004.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase 1197490 metE 4796963 metE Lactococcus lactis subsp. cremoris MG1363 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase YP_001032534.1 1195217 D 416870 CDS YP_001032535.1 125624052 4798873 1197480..1198337 1 NC_009004.1 PF02219: Methylenetetrahydrofolate reductase, TIGR00676: 5,10-methylenetetrahydrofolate reductase; High confidence in function and specificity; 5,10-methylenetetrahydrofolate reductase 1198337 metF 4798873 metF Lactococcus lactis subsp. cremoris MG1363 5,10-methylenetetrahydrofolate reductase YP_001032535.1 1197480 D 416870 CDS YP_001032536.1 125624053 4798884 1198699..1199721 1 NC_009004.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 1199721 aroH 4798884 aroH Lactococcus lactis subsp. cremoris MG1363 phospho-2-dehydro-3-deoxyheptonate aldolase YP_001032536.1 1198699 D 416870 CDS YP_001032537.1 125624054 4798267 complement(1199843..1200025) 1 NC_009004.1 Region start changed from 1200064 to 1200025 (-39 bases); hypothetical protein 1200025 4798267 llmg_1228 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032537.1 1199843 R 416870 CDS YP_001032538.1 125624055 4798224 1200210..1200380 1 NC_009004.1 hypothetical protein 1200380 4798224 llmg_1229 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032538.1 1200210 D 416870 CDS YP_001032539.1 125624056 4798188 1200421..1201662 1 NC_009004.1 membrane protein; hypothetical protein 1201662 4798188 llmg_1230 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032539.1 1200421 D 416870 CDS YP_001032540.1 125624057 4797129 complement(1202589..1203170) 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 1203170 4797129 llmg_1231 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032540.1 1202589 R 416870 CDS YP_001032541.1 125624058 4797948 1203241..1203531 1 NC_009004.1 transposase helper protein for IS904; hypothetical protein 1203531 4797948 llmg_1232 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032541.1 1203241 D 416870 CDS YP_001032542.1 125624059 4797919 complement(1203668..1204507) 1 NC_009004.1 PF00665: Integrase core domain; High confidence in function and specificity; transposase for insertion element IS981J 1204507 tnp981 4797919 tnp981 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion element IS981J YP_001032542.1 1203668 R 416870 CDS YP_001032543.1 125624060 4797274 complement(1204519..1204779) 1 NC_009004.1 transposase helper protein for IS981; hypothetical protein 1204779 4797274 llmg_1234 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032543.1 1204519 R 416870 CDS YP_001032544.1 125624061 4797918 complement(1205420..1206076) 1 NC_009004.1 PF00027: Cyclic nucleotide-binding domain; Conserved hypothetical protein; cyclic nucleotide-binding domain-containing protein 1206076 4797918 llmg_1235 Lactococcus lactis subsp. cremoris MG1363 cyclic nucleotide-binding domain-containing protein YP_001032544.1 1205420 R 416870 CDS YP_001032545.1 125624062 4797898 1206198..1206809 1 NC_009004.1 membrane protein; hypothetical protein 1206809 4797898 llmg_1236 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032545.1 1206198 D 416870 CDS YP_001032546.1 125624063 4797888 1207355..1208293 1 NC_009004.1 High confidence in function and specificity; N5-carboxyethyl-ornithine synthase 1208293 ceo 4797888 ceo Lactococcus lactis subsp. cremoris MG1363 N5-carboxyethyl-ornithine synthase YP_001032546.1 1207355 D 416870 CDS YP_001032547.1 125624064 4798101 1209297..1209497 1 NC_009004.1 PF00313: 'Cold-shock' DNA-binding domain; Conserved hypothetical protein; cold shock-like protein cspD2 1209497 cspD2 4798101 cspD2 Lactococcus lactis subsp. cremoris MG1363 cold shock-like protein cspD2 YP_001032547.1 1209297 D 416870 CDS YP_001032548.1 125624065 4797491 1210978..1212060 1 NC_009004.1 PF01380: Sugar isomerase (SIS); hypothetical protein 1212060 4797491 llmg_1240 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032548.1 1210978 D 416870 CDS YP_001032549.1 125624066 4797840 1212077..1212787 1 NC_009004.1 pseudogene; hypothetical protein 1212787 4797840 llmg_1241 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032549.1 1212077 D 416870 CDS YP_001032550.1 125624067 4798411 1212815..1213036 1 NC_009004.1 pseudogene; hypothetical protein 1213036 4798411 llmg_1242 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032550.1 1212815 D 416870 CDS YP_001032551.1 125624068 4797458 1213067..1215454 1 NC_009004.1 endoglucanase, IPR008928: Glycoside transferase, six-hairpin; High confidence in function and specificity; hypothetical protein 1215454 4797458 llmg_1243 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032551.1 1213067 D 416870 CDS YP_001032552.1 125624069 4797457 1215435..1216742 1 NC_009004.1 hypothetical protein 1216742 4797457 llmg_1244 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032552.1 1215435 D 416870 CDS YP_001032553.1 125624070 4797465 1216780..1217592 1 NC_009004.1 hydrolase, haloacid dehalogenase-like family, TIGR00099: Cof-like hydrolase; hypothetical protein 1217592 4797465 llmg_1245 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032553.1 1216780 D 416870 CDS YP_001032554.1 125624071 4797463 1217893..1218216 1 NC_009004.1 High confidence in function and specificity; regulator of arsenical resistance 1218216 arsR 4797463 arsR Lactococcus lactis subsp. cremoris MG1363 regulator of arsenical resistance YP_001032554.1 1217893 D 416870 CDS YP_001032555.1 125624072 4797233 1218231..1218626 1 NC_009004.1 PF06953: Arsenical resistance operon trans-acting repressor ArsD; Conserved hypothetical protein; arsenical resistance operon trans-acting repressor arsD 1218626 arsD 4797233 arsD Lactococcus lactis subsp. cremoris MG1363 arsenical resistance operon trans-acting repressor arsD YP_001032555.1 1218231 D 416870 CDS YP_001032556.1 125624073 4797240 1218639..1220354 1 NC_009004.1 PF02374: Anion-transporting ATPase, TIGR00345: arsenite-activated ATPase; High confidence in function and specificity; arsenical pump-driving ATPase 1220354 arsA 4797240 arsA Lactococcus lactis subsp. cremoris MG1363 arsenical pump-driving ATPase YP_001032556.1 1218639 D 416870 CDS YP_001032557.1 125624074 4798264 1220371..1222032 1 NC_009004.1 pyridine nucleotide-disulphide oxidoreductase, PF00070: Pyridine nucleotide-disulphide oxidoreductase; hypothetical protein 1222032 4798264 llmg_1249 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032557.1 1220371 D 416870 CDS YP_001032558.1 125624075 4797472 1222048..1223100 1 NC_009004.1 PF01758: Sodium Bile acid symporter family, TIGR00832: arsenical-resistance protein; Conserved hypothetical protein; arsenical-resistance protein 1223100 4797472 llmg_1250 Lactococcus lactis subsp. cremoris MG1363 arsenical-resistance protein YP_001032558.1 1222048 D 416870 CDS YP_001032559.1 125624076 4797468 1223109..1223312 1 NC_009004.1 hypothetical protein 1223312 4797468 llmg_1251 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032559.1 1223109 D 416870 CDS YP_001032560.1 125624077 4797456 complement(1223857..1224258) 1 NC_009004.1 transcriptional regulator, IPR009061: DNA binding; hypothetical protein 1224258 4797456 llmg_1252 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032560.1 1223857 R 416870 CDS YP_001032561.1 125624078 4797428 1224964..1225821 1 NC_009004.1 aldo/keto reductase, PF00248: Aldo/keto reductase; hypothetical protein 1225821 4797428 llmg_1253 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032561.1 1224964 D 416870 CDS YP_001032562.1 125624079 4798225 1226569..1226769 1 NC_009004.1 hypothetical protein 1226769 4798225 llmg_1254 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032562.1 1226569 D 416870 CDS YP_001032563.1 125624080 4797470 1226900..1227100 1 NC_009004.1 IPR008994: Nucleic acid-binding OB-fold, PF00313: 'Cold-shock' DNA-binding domain; Conserved hypothetical protein; cold shock protein cspC 1227100 cspC 4797470 cspC Lactococcus lactis subsp. cremoris MG1363 cold shock protein cspC YP_001032563.1 1226900 D 416870 CDS YP_001032564.1 125624081 4798824 1227378..1227578 1 NC_009004.1 PF00313: Cold-shock protein, DNA-binding; Conserved hypothetical protein; cold shock protein cspD 1227578 cspD 4798824 cspD Lactococcus lactis subsp. cremoris MG1363 cold shock protein cspD YP_001032564.1 1227378 D 416870 CDS YP_001032565.1 125624082 4798833 1228094..1228333 1 NC_009004.1 membrane protein, PF04226: Transglycosylase-associated protein; hypothetical protein 1228333 4798833 llmg_1257 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032565.1 1228094 D 416870 CDS YP_001032566.1 125624083 4798744 1228363..1228923 1 NC_009004.1 membrane protein; hypothetical protein 1228923 4798744 llmg_1258 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032566.1 1228363 D 416870 CDS YP_001032567.1 125624084 4798462 1228933..1229121 1 NC_009004.1 membrane protein; hypothetical protein 1229121 4798462 llmg_1259 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032567.1 1228933 D 416870 CDS YP_001032568.1 125624085 4798450 1229142..1229402 1 NC_009004.1 pseudogene, general stress protein, PF03780: Protein of unknown function DUF322; hypothetical protein 1229402 4798450 llmg_1260 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032568.1 1229142 D 416870 CDS YP_001032569.1 125624086 4797366 complement(1229451..1230209) 1 NC_009004.1 PF01695: IstB-like ATP-binding protein; Conserved hypothetical protein; transposase helper protein for IS712F 1230209 4797366 llmg_1261 Lactococcus lactis subsp. cremoris MG1363 transposase helper protein for IS712F YP_001032569.1 1229451 R 416870 CDS YP_001032570.1 125624087 4797787 complement(1230221..1231444) 1 NC_009004.1 PF00665: Integrase core domain; Conserved hypothetical protein; transposase for insertion sequence element IS712F 1231444 tnp712 4797787 tnp712 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS712F YP_001032570.1 1230221 R 416870 CDS YP_001032571.1 125624088 4796584 1231488..1231862 1 NC_009004.1 pseudogene, general stress protein, PF03780: Protein of unknown function DUF322; hypothetical protein 1231862 4796584 llmg_1263 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032571.1 1231488 D 416870 CDS YP_001032572.1 125624089 4799016 1232254..1232514 1 NC_009004.1 Conserved hypothetical protein; transposase helper protein for IS981 1232514 4799016 llmg_1264 Lactococcus lactis subsp. cremoris MG1363 transposase helper protein for IS981 YP_001032572.1 1232254 D 416870 CDS YP_001032573.1 125624090 4798033 1232526..1233140 1 NC_009004.1 Conserved hypothetical protein; transposase for insertion sequence element IS981J 1233140 tnp981 4798033 tnp981 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS981J YP_001032573.1 1232526 D 416870 CDS YP_001032574.1 125624091 4797467 1234522..1234869 1 NC_009004.1 hypothetical protein 1234869 4797467 llmg_1267 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032574.1 1234522 D 416870 CDS YP_001032575.1 125624092 4797744 1236405..1237460 1 NC_009004.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerS; site-specific tyrosine recombinase XerS 1237460 xerS 4797744 xerS Lactococcus lactis subsp. cremoris MG1363 site-specific tyrosine recombinase XerS YP_001032575.1 1236405 D 416870 CDS YP_001032576.1 125624093 4796826 1237544..1237831 1 NC_009004.1 hypothetical protein 1237831 4796826 llmg_1269 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032576.1 1237544 D 416870 CDS YP_001032577.1 125624094 4798583 1238314..1239384 1 NC_009004.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerS; site-specific tyrosine recombinase XerS 1239384 xerS 4798583 xerS Lactococcus lactis subsp. cremoris MG1363 site-specific tyrosine recombinase XerS YP_001032577.1 1238314 D 416870 CDS YP_001032578.1 125624095 4798788 complement(1239434..1240780) 1 NC_009004.1 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; tRNA (uracil-5-)-methyltransferase Gid 1240780 gidC 4798788 gidC Lactococcus lactis subsp. cremoris MG1363 tRNA (uracil-5-)-methyltransferase Gid YP_001032578.1 1239434 R 416870 CDS YP_001032579.1 125624096 4798178 complement(1240852..1242978) 1 NC_009004.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1242978 topA 4798178 topA Lactococcus lactis subsp. cremoris MG1363 DNA topoisomerase I YP_001032579.1 1240852 R 416870 CDS YP_001032580.1 125624097 4797917 complement(1243244..1244092) 1 NC_009004.1 PF02481: SMF family, TIGR00732: DNA processing protein DprA, Conserved hypothetical protein; Smf protein 1244092 smf 4797917 smf Lactococcus lactis subsp. cremoris MG1363 Smf protein YP_001032580.1 1243244 R 416870 CDS YP_001032581.1 125624098 4796684 complement(1244240..1244620) 1 NC_009004.1 translation initiation inhibitor, PF01042: Endoribonuclease L-PSP, TIGR00004: endoribonuclease L-PSP, Conserved hypothetical protein; regulator AldR 1244620 aldR 4796684 aldR Lactococcus lactis subsp. cremoris MG1363 regulator AldR YP_001032581.1 1244240 R 416870 CDS YP_001032582.1 125624099 4796602 complement(1244660..1245370) 1 NC_009004.1 PF03306: Alpha-acetolactate decarboxylase, TIGR01252: alpha-acetolactate decarboxylase; High confidence in function and specificity; AldB protein 1245370 aldB 4796602 aldB Lactococcus lactis subsp. cremoris MG1363 AldB protein YP_001032582.1 1244660 R 416870 CDS YP_001032583.1 125624100 4797499 complement(1245506..1246756) 1 NC_009004.1 catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic; threonine dehydratase 1246756 ilvA 4797499 ilvA Lactococcus lactis subsp. cremoris MG1363 threonine dehydratase YP_001032583.1 1245506 R 416870 CDS YP_001032584.1 125624101 4796658 complement(1246815..1247837) 1 NC_009004.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 1247837 ilvC 4796658 ilvC Lactococcus lactis subsp. cremoris MG1363 ketol-acid reductoisomerase YP_001032584.1 1246815 R 416870 CDS YP_001032585.1 125624102 4798565 complement(1247882..1248358) 1 NC_009004.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 1248358 ilvH 4798565 ilvH Lactococcus lactis subsp. cremoris MG1363 acetolactate synthase 3 regulatory subunit YP_001032585.1 1247882 R 416870 CDS YP_001032586.1 125624103 4797629 complement(1248351..1250075) 1 NC_009004.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase catalytic subunit 1250075 ilvB 4797629 ilvB Lactococcus lactis subsp. cremoris MG1363 acetolactate synthase catalytic subunit YP_001032586.1 1248351 R 416870 CDS YP_001032587.1 125624104 4797714 complement(1250090..1251802) 1 NC_009004.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 1251802 ilvD 4797714 ilvD Lactococcus lactis subsp. cremoris MG1363 dihydroxy-acid dehydratase YP_001032587.1 1250090 R 416870 CDS YP_001032588.1 125624105 4797673 complement(1251922..1252758) 1 NC_009004.1 PF00005: ABC transporter; Conserved hypothetical protein; ABC transporter ATP-binding protein 1252758 4797673 llmg_1281 Lactococcus lactis subsp. cremoris MG1363 ABC transporter ATP-binding protein YP_001032588.1 1251922 R 416870 CDS YP_001032589.1 125624106 4799063 complement(1252718..1253293) 1 NC_009004.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 1253293 leuD 4799063 leuD Lactococcus lactis subsp. cremoris MG1363 isopropylmalate isomerase small subunit YP_001032589.1 1252718 R 416870 CDS YP_001032590.1 125624107 4798333 complement(1253342..1253875) 1 NC_009004.1 membrane protein; hypothetical protein 1253875 4798333 llmg_1283 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032590.1 1253342 R 416870 CDS YP_001032591.1 125624108 4796776 complement(1253875..1255251) 1 NC_009004.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 1255251 leuC 4796776 leuC Lactococcus lactis subsp. cremoris MG1363 isopropylmalate isomerase large subunit YP_001032591.1 1253875 R 416870 CDS YP_001032592.1 125624109 4796611 1258411..1259370 1 NC_009004.1 PF00581: Rhodanese-like domain; hypothetical protein 1259370 4796611 llmg_1287 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032592.1 1258411 D 416870 CDS YP_001032593.1 125624110 4798511 complement(1259403..1260188) 1 NC_009004.1 IPR010140: Histidinol phosphate phosphatase, HisJ, TIGR01856: histidinol phosphate phosphatase HisJ family; High confidence in function and specificity; histidinol-phosphatase 1260188 hisK 4798511 hisK Lactococcus lactis subsp. cremoris MG1363 histidinol-phosphatase YP_001032593.1 1259403 R 416870 CDS YP_001032594.1 125624111 4799118 complement(1260189..1260827) 1 NC_009004.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase 1260827 hisI 4799118 hisI Lactococcus lactis subsp. cremoris MG1363 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase YP_001032594.1 1260189 R 416870 CDS YP_001032595.1 125624112 4797606 complement(1260824..1261603) 1 NC_009004.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 1261603 hisF 4797606 hisF Lactococcus lactis subsp. cremoris MG1363 imidazole glycerol phosphate synthase subunit HisF YP_001032595.1 1260824 R 416870 CDS YP_001032596.1 125624113 4797807 complement(1261572..1262312) 1 NC_009004.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 1262312 hisA 4797807 hisA Lactococcus lactis subsp. cremoris MG1363 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase YP_001032596.1 1261572 R 416870 CDS YP_001032597.1 125624114 4798340 complement(1262312..1262920) 1 NC_009004.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 1262920 hisH 4798340 hisH Lactococcus lactis subsp. cremoris MG1363 imidazole glycerol phosphate synthase subunit HisH YP_001032597.1 1262312 R 416870 CDS YP_001032598.1 125624115 4798068 complement(1262971..1263759) 1 NC_009004.1 kanamycin kinase , PF01636: Phosphotransferase enzyme family; hypothetical protein 1263759 4798068 llmg_1293 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032598.1 1262971 R 416870 CDS YP_001032599.1 125624116 4798854 complement(1263756..1264355) 1 NC_009004.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; imidazoleglycerol-phosphate dehydratase 1264355 hisB 4798854 hisB Lactococcus lactis subsp. cremoris MG1363 imidazoleglycerol-phosphate dehydratase YP_001032599.1 1263756 R 416870 CDS YP_001032600.1 125624117 4798351 complement(1264356..1265663) 1 NC_009004.1 PF00815: Histidinol dehydrogenase, TIGR00069: histidinol dehydrogenase; High confidence in function and specificity; HisD protein 1265663 hisD 4798351 hisD Lactococcus lactis subsp. cremoris MG1363 HisD protein YP_001032600.1 1264356 R 416870 CDS YP_001032601.1 125624118 4798549 complement(1265647..1266273) 1 NC_009004.1 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ; ATP phosphoribosyltransferase 1266273 hisG 4798549 hisG Lactococcus lactis subsp. cremoris MG1363 ATP phosphoribosyltransferase YP_001032601.1 1265647 R 416870 CDS YP_001032602.1 125624119 4798491 complement(1266502..1267458) 1 NC_009004.1 IPR006195: Aminoacyl-transfer RNA synthetase, class II; High confidence in function and specificity; ATP phosphoribosyltransferase 1267458 hisZ 4798491 hisZ Lactococcus lactis subsp. cremoris MG1363 ATP phosphoribosyltransferase YP_001032602.1 1266502 R 416870 CDS YP_001032603.1 125624120 4798509 complement(1267458..1268528) 1 NC_009004.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 1268528 hisC 4798509 hisC Lactococcus lactis subsp. cremoris MG1363 histidinol-phosphate aminotransferase YP_001032603.1 1267458 R 416870 CDS YP_001032604.1 125624121 4796813 complement(1269077..1269691) 1 NC_009004.1 pseudogene, membrane protein, PF06966: Protein of unknown function DUF1295; hypothetical protein 1269691 4796813 llmg_1299 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032604.1 1269077 R 416870 CDS YP_001032605.1 125624122 4797476 complement(1269721..1269849) 1 NC_009004.1 pseudogene, membrane protein, PF06966: Protein of unknown function DUF1295; hypothetical protein 1269849 4797476 llmg_1300 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032605.1 1269721 R 416870 CDS YP_001032606.1 125624123 4797417 complement(1269846..1271642) 1 NC_009004.1 PF02645: DegV, PF02734: DAK2 domain; hypothetical protein 1271642 4797417 llmg_1301 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032606.1 1269846 R 416870 CDS YP_001032607.1 125624124 4797455 complement(1271646..1272047) 1 NC_009004.1 membrane protein; hypothetical protein 1272047 4797455 llmg_1302 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032607.1 1271646 R 416870 CDS YP_001032608.1 125624125 4796827 complement(1272123..1272602) 1 NC_009004.1 sensory protein, PF03073: TspO/MBR family; hypothetical protein 1272602 4796827 llmg_1303 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032608.1 1272123 R 416870 CDS YP_001032609.1 125624126 4796937 complement(1272922..1274925) 1 NC_009004.1 PF00773: RNB-like protein, TIGR02063: ribonuclease R; High confidence in function and specificity; exoribonuclease R 1274925 vacB2 4796937 vacB2 Lactococcus lactis subsp. cremoris MG1363 exoribonuclease R YP_001032609.1 1272922 R 416870 CDS YP_001032610.1 125624127 4798438 complement(1275130..1275462) 1 NC_009004.1 PF01381: Helix-turn-helix; transcriptional regulator 1275462 4798438 llmg_1305 Lactococcus lactis subsp. cremoris MG1363 transcriptional regulator YP_001032610.1 1275130 R 416870 CDS YP_001032611.1 125624128 4797530 complement(1275928..1278375) 1 NC_009004.1 adhesin precursor, IPR008985: Concanavalin A-like lectin/glucanase, PF05738: Cna protein B-type domain; hypothetical protein 1278375 4797530 llmg_1306 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032611.1 1275928 R 416870 CDS YP_001032612.1 125624129 4797601 complement(1279042..1279197) 1 NC_009004.1 hypothetical protein 1279197 4797601 llmg_1308 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032612.1 1279042 R 416870 CDS YP_001032613.1 125624130 4797159 complement(1279940..1281604) 1 NC_009004.1 catalyzes the formation of 2-acetolactate from pyruvate in stationary phase; acetolactate synthase 1281604 als 4797159 als Lactococcus lactis subsp. cremoris MG1363 acetolactate synthase YP_001032613.1 1279940 R 416870 CDS YP_001032614.1 125624131 4796609 complement(1281759..1283015) 1 NC_009004.1 TPR domain protein; hypothetical protein 1283015 4796609 llmg_1310 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032614.1 1281759 R 416870 CDS YP_001032615.1 125624132 4796762 complement(1283043..1284215) 1 NC_009004.1 membrane protein, PF01594: Domain of unknown function DUF20; hypothetical protein 1284215 4796762 llmg_1311 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032615.1 1283043 R 416870 CDS YP_001032616.1 125624133 4797957 complement(1284281..1284901) 1 NC_009004.1 methyltransferase; hypothetical protein 1284901 4797957 llmg_1313 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032616.1 1284281 R 416870 CDS YP_001032617.1 125624134 4799116 complement(1284903..1286510) 1 NC_009004.1 hypothetical protein 1286510 4799116 llmg_1314 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032617.1 1284903 R 416870 CDS YP_001032618.1 125624135 4798329 complement(1286555..1287925) 1 NC_009004.1 TIGR00479: 23S rRNA (uracil-5-)-methyltransferase RumA, PF05958: tRNA (Uracil-5-)-methyltransferase , PF01938: TRAM domain; Conserved hypothetical protein; RNA methyltransferase 1287925 4798329 llmg_1315 Lactococcus lactis subsp. cremoris MG1363 RNA methyltransferase YP_001032618.1 1286555 R 416870 CDS YP_001032619.1 125624136 4797433 complement(1287988..1288809) 1 NC_009004.1 PF01380: Sugar isomerase (SIS), PF01418: Helix-turn- helix domain, rpiR family; Conserved hypothetical protein; transcriptional regulator 1288809 4797433 llmg_1316 Lactococcus lactis subsp. cremoris MG1363 transcriptional regulator YP_001032619.1 1287988 R 416870 CDS YP_001032620.1 125624137 4797484 1288947..1289651 1 NC_009004.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 1289651 4797484 llmg_1317 Lactococcus lactis subsp. cremoris MG1363 N-acetylmannosamine-6-phosphate 2-epimerase YP_001032620.1 1288947 D 416870 CDS YP_001032621.1 125624138 4796704 complement(1289736..1292261) 1 NC_009004.1 PF00122: E1-E2 ATPase, TIGR01647: plasma-membrane proton-efflux P-type ATPase; High confidence in function and specificity; cation-transporting ATPase 1292261 4796704 llmg_1318 Lactococcus lactis subsp. cremoris MG1363 cation-transporting ATPase YP_001032621.1 1289736 R 416870 CDS YP_001032622.1 125624139 4796723 1292447..1293622 1 NC_009004.1 PF00872: Transposase, Mutator family; High confidence in function and specificity; transposase for insertion sequence element IS905H 1293622 tnp905 4796723 tnp905 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS905H YP_001032622.1 1292447 D 416870 CDS YP_001032623.1 125624140 4796823 complement(1294199..1295584) 1 NC_009004.1 pseudogene; Conserved hypothetical protein; xylan beta-1,4-xylosidase 1295584 4796823 llmg_1320 Lactococcus lactis subsp. cremoris MG1363 xylan beta-1,4-xylosidase YP_001032623.1 1294199 R 416870 CDS YP_001032624.1 125624141 4796727 complement(1295892..1297073) 1 NC_009004.1 Endoglucanase; hypothetical protein 1297073 4796727 llmg_1321 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032624.1 1295892 R 416870 CDS YP_001032625.1 125624142 4797437 1297370..1298566 1 NC_009004.1 multidrug efflux permease , PF07690: Major facilitator superfamily; hypothetical protein 1298566 4797437 llmg_1322 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032625.1 1297370 D 416870 CDS YP_001032626.1 125624143 4798429 complement(1298942..1300117) 1 NC_009004.1 PF00872: Transposase, Mutator family; High confidence in function and specificity; transposase for insertion sequence element IS905I 1300117 tnp905 4798429 tnp905 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS905I YP_001032626.1 1298942 R 416870 CDS YP_001032627.1 125624144 4798251 1300331..1300786 1 NC_009004.1 pseudogene, PF00165: Bacterial regulatory helix- turn-helix proteins, AraC type; Conserved hypothetical protein; AraC family transcriptional regulator 1300786 4798251 llmg_1324 Lactococcus lactis subsp. cremoris MG1363 AraC family transcriptional regulator YP_001032627.1 1300331 D 416870 CDS YP_001032628.1 125624145 4799050 complement(1301096..1302163) 1 NC_009004.1 Spermidine/putrescine ABC transporter substrate binding; High confidence in function and specificity; spermidine/putrescine ABC transporter substrate-binding protein 1302163 potD 4799050 potD Lactococcus lactis subsp. cremoris MG1363 spermidine/putrescine ABC transporter substrate-binding protein YP_001032628.1 1301096 R 416870 CDS YP_001032629.1 125624146 4797142 complement(1302211..1303011) 1 NC_009004.1 High confidence in function and specificity; spermidine/putrescine ABC transporter permease 1303011 potC 4797142 potC Lactococcus lactis subsp. cremoris MG1363 spermidine/putrescine ABC transporter permease YP_001032629.1 1302211 R 416870 CDS YP_001032630.1 125624147 4797149 complement(1303013..1303801) 1 NC_009004.1 High confidence in function and specificity; spermidine/putrescine ABC transporter permease 1303801 potB 4797149 potB Lactococcus lactis subsp. cremoris MG1363 spermidine/putrescine ABC transporter permease YP_001032630.1 1303013 R 416870 CDS YP_001032631.1 125624148 4796757 complement(1303798..1305078) 1 NC_009004.1 High confidence in function and specificity; spermidine/putrescine ABC transporter ATP-binding protein 1305078 potA 4796757 potA Lactococcus lactis subsp. cremoris MG1363 spermidine/putrescine ABC transporter ATP-binding protein YP_001032631.1 1303798 R 416870 CDS YP_001032632.1 125624149 4796678 complement(1305539..1306438) 1 NC_009004.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 1306438 murB 4796678 murB Lactococcus lactis subsp. cremoris MG1363 UDP-N-acetylenolpyruvoylglucosamine reductase YP_001032632.1 1305539 R 416870 CDS YP_001032633.1 125624150 4797508 complement(1306481..1307149) 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 1307149 4797508 llmg_1330 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032633.1 1306481 R 416870 CDS YP_001032634.1 125624151 4799049 complement(1307334..1308224) 1 NC_009004.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 1308224 thrB 4799049 thrB Lactococcus lactis subsp. cremoris MG1363 homoserine kinase YP_001032634.1 1307334 R 416870 CDS YP_001032635.1 125624152 4796939 complement(1308229..1309515) 1 NC_009004.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 1309515 hom 4796939 hom Lactococcus lactis subsp. cremoris MG1363 homoserine dehydrogenase YP_001032635.1 1308229 R 416870 CDS YP_001032636.1 125624153 4796698 complement(1309696..1310334) 1 NC_009004.1 High confidence in function and specificity; deoxynucleoside kinase 1310334 dukB 4796698 dukB Lactococcus lactis subsp. cremoris MG1363 deoxynucleoside kinase YP_001032636.1 1309696 R 416870 CDS YP_001032637.1 125624154 4798823 complement(1310463..1311746) 1 NC_009004.1 FolC protein 1311746 folC 4798823 folC Lactococcus lactis subsp. cremoris MG1363 FolC protein YP_001032637.1 1310463 R 416870 CDS YP_001032638.1 125624155 4797940 complement(1311762..1312262) 1 NC_009004.1 Also known as ylgG (AAN64308), IPR000086: NUDIX_hydrolase domain (NUcleoside DIphosphate linked to some other moiety X); hypothetical protein 1312262 4797940 llmg_1335 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032638.1 1311762 R 416870 CDS YP_001032639.1 125624156 4796860 complement(1312265..1313338) 1 NC_009004.1 High confidence in function and specificity; dihydropteroate synthase 1313338 folP 4796860 folP Lactococcus lactis subsp. cremoris MG1363 dihydropteroate synthase YP_001032639.1 1312265 R 416870 CDS YP_001032640.1 125624157 4797323 complement(1313335..1314384) 1 NC_009004.1 FolE protein 1314384 folE 4797323 folE Lactococcus lactis subsp. cremoris MG1363 FolE protein YP_001032640.1 1313335 R 416870 CDS YP_001032641.1 125624158 4797968 complement(1314464..1314814) 1 NC_009004.1 High confidence in function and specificity; FolB protein 1314814 folB 4797968 folB Lactococcus lactis subsp. cremoris MG1363 FolB protein YP_001032641.1 1314464 R 416870 CDS YP_001032642.1 125624159 4798135 complement(1314868..1315455) 1 NC_009004.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 1315455 engB 4798135 engB Lactococcus lactis subsp. cremoris MG1363 ribosome biogenesis GTP-binding protein YsxC YP_001032642.1 1314868 R 416870 CDS YP_001032643.1 125624160 4797578 complement(1315452..1316687) 1 NC_009004.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 1316687 clpX 4797578 clpX Lactococcus lactis subsp. cremoris MG1363 ATP-dependent protease ATP-binding subunit ClpX YP_001032643.1 1315452 R 416870 CDS YP_001032644.1 125624161 4796862 complement(1316936..1317442) 1 NC_009004.1 High confidence in function and specificity; DfrA protein 1317442 dfrA 4796862 dfrA Lactococcus lactis subsp. cremoris MG1363 DfrA protein YP_001032644.1 1316936 R 416870 CDS YP_001032645.1 125624162 4798897 1317707..1318297 1 NC_009004.1 rRNA methyltransferase 1318297 spoU 4798897 spoU Lactococcus lactis subsp. cremoris MG1363 rRNA methyltransferase YP_001032645.1 1317707 D 416870 CDS YP_001032646.1 125624163 4797951 1318515..1318862 1 NC_009004.1 hypothetical protein 1318862 4797951 llmg_1344 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032646.1 1318515 D 416870 CDS YP_001032647.1 125624164 4797006 complement(1318899..1320203) 1 NC_009004.1 High confidence in function and specificity; xanthine/uracil permease 1320203 pbuX 4797006 pbuX Lactococcus lactis subsp. cremoris MG1363 xanthine/uracil permease YP_001032647.1 1318899 R 416870 CDS YP_001032648.1 125624165 4798145 complement(1320261..1320854) 1 NC_009004.1 Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine; xanthine phosphoribosyltransferase 1320854 xpt 4798145 xpt Lactococcus lactis subsp. cremoris MG1363 xanthine phosphoribosyltransferase YP_001032648.1 1320261 R 416870 CDS YP_001032649.1 125624166 4797864 complement(1321531..1321815) 1 NC_009004.1 ORF59; transcriptional regulator, IPR010982: Lambda repressor-like, DNA-binding, PF01381: Helix-turn- helix; hypothetical protein 1321815 4797864 llmg_1347 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032649.1 1321531 R 416870 CDS YP_001032650.1 125624167 4797008 complement(1321802..1322167) 1 NC_009004.1 ORF58; hypothetical protein 1322167 4797008 llmg_1348 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032650.1 1321802 R 416870 CDS YP_001032651.1 125624168 4796953 complement(1322595..1323665) 1 NC_009004.1 ORF57; integral membrane protein, PF04332: Protein of unknown function DUF475; hypothetical protein 1323665 4796953 llmg_1349 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032651.1 1322595 R 416870 CDS YP_001032652.1 125624169 4797011 complement(1323752..1324327) 1 NC_009004.1 PF02342: Bacterial stress protein; Conserved hypothetical protein; tellurium resistance protein 1324327 telC 4797011 telC Lactococcus lactis subsp. cremoris MG1363 tellurium resistance protein YP_001032652.1 1323752 R 416870 CDS YP_001032653.1 125624170 4796966 complement(1324343..1324918) 1 NC_009004.1 PF02342: Bacterial stress protein; Conserved hypothetical protein; tellurium resistance protein 1324918 telB 4796966 telB Lactococcus lactis subsp. cremoris MG1363 tellurium resistance protein YP_001032653.1 1324343 R 416870 CDS YP_001032654.1 125624171 4797061 complement(1324928..1325551) 1 NC_009004.1 PF02342: Bacterial stress protein; Conserved hypothetical protein; tellurium resistance protein 1325551 telA 4797061 telA Lactococcus lactis subsp. cremoris MG1363 tellurium resistance protein YP_001032654.1 1324928 R 416870 CDS YP_001032655.1 125624172 4798216 complement(1325631..1326728) 1 NC_009004.1 ORF53; PF05816: Toxic anion resistance protein (TelA); tellurite resistance protein 1326728 4798216 llmg_1353 Lactococcus lactis subsp. cremoris MG1363 tellurite resistance protein YP_001032655.1 1325631 R 416870 CDS YP_001032656.1 125624173 4797095 complement(1326746..1328350) 1 NC_009004.1 ORF52; hypothetical protein 1328350 4797095 llmg_1354 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032656.1 1326746 R 416870 CDS YP_001032657.1 125624174 4798227 complement(1328376..1329197) 1 NC_009004.1 ORF51; hypothetical protein 1329197 4798227 llmg_1355 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032657.1 1328376 R 416870 CDS YP_001032658.1 125624175 4797137 complement(1329199..1330305) 1 NC_009004.1 ORF50; hypothetical protein 1330305 4797137 llmg_1356 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032658.1 1329199 R 416870 CDS YP_001032659.1 125624176 4798036 complement(1330302..1331498) 1 NC_009004.1 ORF49; hypothetical protein 1331498 4798036 llmg_1357 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032659.1 1330302 R 416870 CDS YP_001032660.1 125624177 4797278 complement(1331491..1332717) 1 NC_009004.1 ORF48; hypothetical protein 1332717 4797278 llmg_1358 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032660.1 1331491 R 416870 CDS YP_001032661.1 125624178 4797340 complement(1334029..1334313) 1 NC_009004.1 ORF47; transcriptional regulator, IPR010982: Lambda repressor-like, DNA-binding, PF01381: Helix-turn- helix; hypothetical protein 1334313 4797340 llmg_1359 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032661.1 1334029 R 416870 CDS YP_001032662.1 125624179 4798441 complement(1334300..1334665) 1 NC_009004.1 ORF46; hypothetical protein 1334665 4798441 llmg_1360 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032662.1 1334300 R 416870 CDS YP_001032663.1 125624180 4797858 complement(1334736..1335809) 1 NC_009004.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerS; site-specific tyrosine recombinase XerS 1335809 xerS 4797858 xerS Lactococcus lactis subsp. cremoris MG1363 site-specific tyrosine recombinase XerS YP_001032663.1 1334736 R 416870 CDS YP_001032664.1 125624181 4797847 complement(1335893..1336165) 1 NC_009004.1 ORF44; hypothetical protein 1336165 4797847 llmg_1362 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032664.1 1335893 R 416870 CDS YP_001032665.1 125624182 4798336 complement(1337148..1337708) 1 NC_009004.1 ORF43; hypothetical protein 1337708 4798336 llmg_1364 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032665.1 1337148 R 416870 CDS YP_001032666.1 125624183 4798288 complement(1338108..1338746) 1 NC_009004.1 ORF42; hypothetical protein 1338746 4798288 llmg_1365 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032666.1 1338108 R 416870 CDS YP_001032667.1 125624184 4798126 complement(1339191..1341710) 1 NC_009004.1 ORF41; hypothetical protein 1341710 4798126 llmg_1366 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032667.1 1339191 R 416870 CDS YP_001032668.1 125624185 4796822 complement(1342117..1342956) 1 NC_009004.1 High confidence in function and specificity; transposase for insertion sequence element IS981K 1342956 tnp981 4796822 tnp981 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS981K YP_001032668.1 1342117 R 416870 CDS YP_001032669.1 125624186 4797252 complement(1342968..1343228) 1 NC_009004.1 ORF39; transposase helper protein for IS981 1343228 4797252 llmg_1368 Lactococcus lactis subsp. cremoris MG1363 transposase helper protein for IS981 YP_001032669.1 1342968 R 416870 CDS YP_001032670.1 125624187 4798029 complement(1343265..1343921) 1 NC_009004.1 ORF38; hypothetical protein 1343921 4798029 llmg_1369 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032670.1 1343265 R 416870 CDS YP_001032671.1 125624189 4798958 complement(join(1344187..1345428,1347858..1348370)) 1 NC_009004.1 Mobilisation protein; hypothetical protein 1348370 4798958 llmg_1369a Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032671.1 1344187 R 416870 CDS YP_001032672.1 125624188 4797413 complement(1345518..1347317) 1 NC_009004.1 maturase 1347317 matR 4797413 matR Lactococcus lactis subsp. cremoris MG1363 maturase YP_001032672.1 1345518 R 416870 CDS YP_001032673.1 125624190 4798765 complement(1348370..1348726) 1 NC_009004.1 ORF34; IPR008687: Bacterial mobilisation; hypothetical protein 1348726 4798765 llmg_1373 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032673.1 1348370 R 416870 CDS YP_001032674.1 125624191 4798641 complement(1348769..1349419) 1 NC_009004.1 DNA topoisomerase, IPR000380: DNA topoisomerase I; High confidence in function and specificity; LtrE protein 1349419 ltrE 4798641 ltrE Lactococcus lactis subsp. cremoris MG1363 LtrE protein YP_001032674.1 1348769 R 416870 CDS YP_001032675.1 125624192 4797695 complement(1349704..1350180) 1 NC_009004.1 LtrD protein 1350180 ltrD 4797695 ltrD Lactococcus lactis subsp. cremoris MG1363 LtrD protein YP_001032675.1 1349704 R 416870 CDS YP_001032676.1 125624193 4797640 complement(1350253..1351905) 1 NC_009004.1 Conserved hypothetical protein; LtrC protein 1351905 ltrC 4797640 ltrC Lactococcus lactis subsp. cremoris MG1363 LtrC protein YP_001032676.1 1350253 R 416870 CDS YP_001032677.1 125624194 4797689 complement(1351957..1353723) 1 NC_009004.1 ORF30; hypothetical protein 1353723 4797689 llmg_1377 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032677.1 1351957 R 416870 CDS YP_001032678.1 125624195 4798507 complement(1353704..1354219) 1 NC_009004.1 ORF29; hypothetical protein 1354219 4798507 llmg_1378 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032678.1 1353704 R 416870 CDS YP_001032679.1 125624196 4798023 complement(1354233..1355417) 1 NC_009004.1 ORF28; Conserved hypothetical protein; Zn peptidase 1355417 4798023 llmg_1379 Lactococcus lactis subsp. cremoris MG1363 Zn peptidase YP_001032679.1 1354233 R 416870 CDS YP_001032680.1 125624197 4798778 complement(1355479..1355673) 1 NC_009004.1 ORF27; hypothetical protein 1355673 4798778 llmg_1381 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032680.1 1355479 R 416870 CDS YP_001032681.1 125624198 4796872 complement(1355782..1356846) 1 NC_009004.1 ORF26; hypothetical protein 1356846 4796872 llmg_1382 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032681.1 1355782 R 416870 CDS YP_001032682.1 125624199 4796645 complement(1356872..1358710) 1 NC_009004.1 PF02534: TraG/TraD family; Conserved hypothetical protein; conjugal transfer protein TraD 1358710 traD 4796645 traD Lactococcus lactis subsp. cremoris MG1363 conjugal transfer protein TraD YP_001032682.1 1356872 R 416870 CDS YP_001032683.1 125624200 4797163 complement(1358707..1359210) 1 NC_009004.1 ORF24; hypothetical protein 1359210 4797163 llmg_1384 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032683.1 1358707 R 416870 CDS YP_001032684.1 125624201 4798471 complement(1359189..1359407) 1 NC_009004.1 ORF23; hypothetical protein 1359407 4798471 llmg_1385 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032684.1 1359189 R 416870 CDS YP_001032685.1 125624202 4798559 complement(1359423..1360736) 1 NC_009004.1 ORF22; Conserved hypothetical protein; hypothetical protein 1360736 4798559 llmg_1386 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032685.1 1359423 R 416870 CDS YP_001032686.1 125624203 4798852 complement(1360736..1360981) 1 NC_009004.1 ORF21; Specificity unclear; hypothetical protein 1360981 4798852 llmg_1387 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032686.1 1360736 R 416870 CDS YP_001032687.1 125624204 4798858 complement(1360982..1361674) 1 NC_009004.1 ORF20; membrane protein; hypothetical protein 1361674 4798858 llmg_1388 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032687.1 1360982 R 416870 CDS YP_001032688.1 125624205 4797111 complement(1361700..1362017) 1 NC_009004.1 ORF19; hypothetical protein 1362017 4797111 llmg_1389 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032688.1 1361700 R 416870 CDS YP_001032689.1 125624206 4796960 complement(1362027..1364639) 1 NC_009004.1 ORF18; hypothetical protein 1364639 4796960 llmg_1390 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032689.1 1362027 R 416870 CDS YP_001032690.1 125624207 4798100 complement(1364643..1366889) 1 NC_009004.1 Region start changed from 1367033 to 1366889 (-144 bases); hypothetical protein 1366889 4798100 llmg_1391 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032690.1 1364643 R 416870 CDS YP_001032691.1 125624208 4797119 complement(1366987..1367340) 1 NC_009004.1 ORF16; hypothetical protein 1367340 4797119 llmg_1392 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032691.1 1366987 R 416870 CDS YP_001032692.1 125624209 4796887 complement(1367342..1368130) 1 NC_009004.1 ORF15; hypothetical protein 1368130 4796887 llmg_1393 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032692.1 1367342 R 416870 CDS YP_001032693.1 125624210 4796974 complement(1368421..1368819) 1 NC_009004.1 ORF14; hypothetical protein 1368819 4796974 llmg_1395 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032693.1 1368421 R 416870 CDS YP_001032694.1 125624211 4796843 complement(1368792..1368962) 1 NC_009004.1 ORF13; hypothetical protein 1368962 4796843 llmg_1396 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032694.1 1368792 R 416870 CDS YP_001032695.1 125624212 4798163 complement(1368981..1369139) 1 NC_009004.1 ORF12; hypothetical protein 1369139 4798163 llmg_1397 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032695.1 1368981 R 416870 CDS YP_001032696.1 125624213 4798533 complement(1369190..1372921) 1 NC_009004.1 Bacterial adhesion involved in high frequency conjugation, peptidoglycan linked, gram positive LPXTG cell wall anchor, signal peptide; High confidence in function and specificity; cell surface antigen I/II precursor 1372921 cluA 4798533 cluA Lactococcus lactis subsp. cremoris MG1363 cell surface antigen I/II precursor YP_001032696.1 1369190 R 416870 CDS YP_001032697.1 125624214 4797960 complement(1373131..1374153) 1 NC_009004.1 ORF10; hypothetical protein 1374153 4797960 llmg_1399 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032697.1 1373131 R 416870 CDS YP_001032698.1 125624215 4798566 complement(1374171..1374470) 1 NC_009004.1 ORF9; PF00226: DnaJ domain; hypothetical protein 1374470 4798566 llmg_1400 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032698.1 1374171 R 416870 CDS YP_001032699.1 125624216 4796795 complement(1375104..1375466) 1 NC_009004.1 ORF8; hypothetical protein 1375466 4796795 llmg_1402 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032699.1 1375104 R 416870 CDS YP_001032700.1 125624217 4799062 complement(1375896..1376435) 1 NC_009004.1 ORF7; hypothetical protein 1376435 4799062 llmg_1403 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032700.1 1375896 R 416870 CDS YP_001032701.1 125624218 4796798 complement(1376846..1377109) 1 NC_009004.1 ORF6; hypothetical protein 1377109 4796798 llmg_1406 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032701.1 1376846 R 416870 CDS YP_001032702.1 125624219 4798508 complement(1377114..1377311) 1 NC_009004.1 ORF5; hypothetical protein 1377311 4798508 llmg_1407 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032702.1 1377114 R 416870 CDS YP_001032703.1 125624220 4798889 complement(1377325..1377522) 1 NC_009004.1 ORF4; hypothetical protein 1377522 4798889 llmg_1408 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032703.1 1377325 R 416870 CDS YP_001032704.1 125624221 4798074 complement(1377548..1378417) 1 NC_009004.1 ORF3; hypothetical protein 1378417 4798074 llmg_1409 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032704.1 1377548 R 416870 CDS YP_001032705.1 125624222 4798108 complement(1378410..1378865) 1 NC_009004.1 ORF2; hypothetical protein 1378865 4798108 llmg_1410 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032705.1 1378410 R 416870 CDS YP_001032706.1 125624223 4798659 complement(1379125..1380063) 1 NC_009004.1 ORF1; hypothetical protein 1380063 4798659 llmg_1411 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032706.1 1379125 R 416870 CDS YP_001032707.1 125624224 4798556 complement(1380599..1381588) 1 NC_009004.1 High confidence in function and specificity; guanosine 5'-monophosphate oxidoreductase 1381588 guaC 4798556 guaC Lactococcus lactis subsp. cremoris MG1363 guanosine 5'-monophosphate oxidoreductase YP_001032707.1 1380599 R 416870 CDS YP_001032708.1 125624225 4797528 complement(1381851..1382468) 1 NC_009004.1 Protein of unknown function DUF1461; Family membership; hypothetical protein 1382468 4797528 llmg_1413 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032708.1 1381851 R 416870 CDS YP_001032709.1 125624226 4798077 complement(1382610..1383383) 1 NC_009004.1 phosphatases involved in N-acetyl- glucosamine catabolism, TIGR01457: HAD-SF-IIA-hyp2: HAD- superfamily subfamily IIA hydrolase; High confidence in function and specificity; N-acetylglucosamine catabolic protein 1383383 nagD 4798077 nagD Lactococcus lactis subsp. cremoris MG1363 N-acetylglucosamine catabolic protein YP_001032709.1 1382610 R 416870 CDS YP_001032710.1 125624227 4797574 complement(1383432..1384163) 1 NC_009004.1 Acyl-ACP thioesterase, oleoyl- acyl carrier protein thioesterase; hypothetical protein 1384163 4797574 llmg_1415 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032710.1 1383432 R 416870 CDS YP_001032711.1 125624228 4798842 complement(1384265..1384705) 1 NC_009004.1 hypothetical protein 1384705 4798842 llmg_1416 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032711.1 1384265 R 416870 CDS YP_001032712.1 125624229 4796816 complement(1384807..1385622) 1 NC_009004.1 autolytic lysozyme; Conserved hypothetical protein; hypothetical protein 1385622 4796816 llmg_1417 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032712.1 1384807 R 416870 CDS YP_001032713.1 125624230 4796787 complement(1385668..1386807) 1 NC_009004.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 1386807 hemN 4796787 hemN Lactococcus lactis subsp. cremoris MG1363 coproporphyrinogen III oxidase YP_001032713.1 1385668 R 416870 CDS YP_001032714.1 125624231 4797565 complement(1386995..1387522) 1 NC_009004.1 Conserved hypothetical protein; transcriptional regulator 1387522 4797565 llmg_1419 Lactococcus lactis subsp. cremoris MG1363 transcriptional regulator YP_001032714.1 1386995 R 416870 CDS YP_001032715.1 125624232 4799064 complement(1387504..1388823) 1 NC_009004.1 hypothetical protein 1388823 4799064 llmg_1420 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032715.1 1387504 R 416870 CDS YP_001032716.1 125624233 4796773 complement(1389161..1389562) 1 NC_009004.1 hypothetical protein 1389562 4796773 llmg_1421 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032716.1 1389161 R 416870 CDS YP_001032717.1 125624234 4798501 complement(1389794..1390711) 1 NC_009004.1 PF02275.7: Linear amide C-N hydrolases, choloylglycine hydrolase; High confidence in function and specificity; penicillin acylase 1390711 pacA 4798501 pacA Lactococcus lactis subsp. cremoris MG1363 penicillin acylase YP_001032717.1 1389794 R 416870 CDS YP_001032718.1 125624235 4799076 complement(1390877..1391635) 1 NC_009004.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 1391635 tpiA 4799076 tpiA Lactococcus lactis subsp. cremoris MG1363 triosephosphate isomerase YP_001032718.1 1390877 R 416870 CDS YP_001032719.1 125624236 4798326 complement(1391768..1392619) 1 NC_009004.1 PF01380.10: Contains sugar isomerase (SIS) domain., PF01418.7: Helix-turn-helix protein RpiR; Conserved hypothetical protein; RpiR family transcriptional regulator 1392619 4798326 llmg_1425 Lactococcus lactis subsp. cremoris MG1363 RpiR family transcriptional regulator YP_001032719.1 1391768 R 416870 CDS YP_001032720.1 125624237 4798564 complement(1392681..1394633) 1 NC_009004.1 High confidence in function and specificity; sucrose-specific PTS system IIBC component 1394633 4798564 llmg_1426 Lactococcus lactis subsp. cremoris MG1363 sucrose-specific PTS system IIBC component YP_001032720.1 1392681 R 416870 CDS YP_001032721.1 125624238 4799122 complement(1394669..1395562) 1 NC_009004.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid 6-phosphate etherase 1395562 murQ 4799122 murQ Lactococcus lactis subsp. cremoris MG1363 N-acetylmuramic acid 6-phosphate etherase YP_001032721.1 1394669 R 416870 CDS YP_001032722.1 125624239 4799052 complement(1395555..1396616) 1 NC_009004.1 Bacterial protein of unknown function DUF871; hypothetical protein 1396616 4799052 llmg_1428 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032722.1 1395555 R 416870 CDS YP_001032723.1 125624240 4798805 complement(1396766..1397737) 1 NC_009004.1 High confidence in function and specificity; L-lactate dehydrogenase 1397737 ldhX 4798805 ldhX Lactococcus lactis subsp. cremoris MG1363 L-lactate dehydrogenase YP_001032723.1 1396766 R 416870 CDS YP_001032724.1 125624241 4796614 complement(1397821..1398723) 1 NC_009004.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 1398723 ribC 4796614 ribC Lactococcus lactis subsp. cremoris MG1363 bifunctional riboflavin kinase/FMN adenylyltransferase YP_001032724.1 1397821 R 416870 CDS YP_001032725.1 125624242 4798154 complement(1398755..1399747) 1 NC_009004.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 1399747 truB 4798154 truB Lactococcus lactis subsp. cremoris MG1363 tRNA pseudouridine synthase B YP_001032725.1 1398755 R 416870 CDS YP_001032726.1 125624243 4798203 complement(1399886..1400605) 1 NC_009004.1 hypothetical protein 1400605 4798203 llmg_1432 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032726.1 1399886 R 416870 CDS YP_001032727.1 125624244 4797694 complement(1400795..1403095) 1 NC_009004.1 PF00478: IMP dehydrogenase / GMP reductase domain; Conserved hypothetical protein; hypothetical protein 1403095 4797694 llmg_1433 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032727.1 1400795 R 416870 CDS YP_001032728.1 125624245 4797713 1403462..1403986 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 1403986 4797713 llmg_1434 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032728.1 1403462 D 416870 CDS YP_001032729.1 125624246 4798370 1404048..1404506 1 NC_009004.1 hypothetical protein 1404506 4798370 llmg_1435 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032729.1 1404048 D 416870 CDS YP_001032730.1 125624247 4798383 complement(1404756..1405595) 1 NC_009004.1 Integrase, catalytic region; High confidence in function and specificity; transposase for insertion sequence element IS981L 1405595 tnp981 4798383 tnp981 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS981L YP_001032730.1 1404756 R 416870 CDS YP_001032731.1 125624248 4797247 complement(1405607..1405867) 1 NC_009004.1 transposase helper protein for IS981; hypothetical protein 1405867 4797247 llmg_1438 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032731.1 1405607 R 416870 CDS YP_001032732.1 125624249 4798387 complement(1406092..1407036) 1 NC_009004.1 Protein kinase-like; Family membership; hypothetical protein 1407036 4798387 llmg_1440 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032732.1 1406092 R 416870 CDS YP_001032733.1 125624250 4797182 complement(1407163..1408671) 1 NC_009004.1 Reduces fumarate to succinate in anaerobic bacterial respiration; fumarate reductase flavoprotein subunit 1408671 frdC 4797182 frdC Lactococcus lactis subsp. cremoris MG1363 fumarate reductase flavoprotein subunit YP_001032733.1 1407163 R 416870 CDS YP_001032734.1 125624251 4797861 complement(1408847..1409296) 1 NC_009004.1 Family membership; hypothetical protein 1409296 4797861 llmg_1442 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032734.1 1408847 R 416870 CDS YP_001032735.1 125624252 4798735 complement(1409997..1410464) 1 NC_009004.1 contains NUDIX domain; High confidence in function and specificity; ADP-ribose pyrophosphatase 1410464 mutX 4798735 mutX Lactococcus lactis subsp. cremoris MG1363 ADP-ribose pyrophosphatase YP_001032735.1 1409997 R 416870 CDS YP_001032736.1 125624253 4798182 complement(1410489..1412765) 1 NC_009004.1 High confidence in function and specificity; ATP-dependent DNA helicase 1412765 pcrA 4798182 pcrA Lactococcus lactis subsp. cremoris MG1363 ATP-dependent DNA helicase YP_001032736.1 1410489 R 416870 CDS YP_001032737.1 125624254 4798140 1412917..1413693 1 NC_009004.1 hypothetical protein 1413693 4798140 llmg_1446 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032737.1 1412917 D 416870 CDS YP_001032738.1 125624255 4797157 complement(1413638..1414267) 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 1414267 4797157 llmg_1447 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032738.1 1413638 R 416870 CDS YP_001032739.1 125624256 4796629 complement(1414254..1417007) 1 NC_009004.1 C-terminal end; Specificity unclear; hypothetical protein 1417007 4796629 llmg_1448 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032739.1 1414254 R 416870 CDS YP_001032740.1 125624257 4796566 complement(1417226..1417978) 1 NC_009004.1 High confidence in function and specificity; sortase SrtA 1417978 srtA 4796566 srtA Lactococcus lactis subsp. cremoris MG1363 sortase SrtA YP_001032740.1 1417226 R 416870 CDS YP_001032741.1 125624258 4799114 complement(1418101..1419186) 1 NC_009004.1 High confidence in function and specificity; thiamine biosynthesis lipoprotein apbE precursor 1419186 apbE 4799114 apbE Lactococcus lactis subsp. cremoris MG1363 thiamine biosynthesis lipoprotein apbE precursor YP_001032741.1 1418101 R 416870 CDS YP_001032742.1 125624259 4798945 complement(1419268..1421778) 1 NC_009004.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 1421778 gyrA 4798945 gyrA Lactococcus lactis subsp. cremoris MG1363 DNA gyrase subunit A YP_001032742.1 1419268 R 416870 CDS YP_001032743.1 125624260 4797540 complement(1422000..1423469) 1 NC_009004.1 Contains Amino acid permease-associated region; Function unclear; amino-acid permease 1423469 4797540 llmg_1452 Lactococcus lactis subsp. cremoris MG1363 amino-acid permease YP_001032743.1 1422000 R 416870 CDS YP_001032744.1 125624261 4796724 complement(1423642..1424277) 1 NC_009004.1 Similar to nucleoside-diphosphate-sugar epimerases; Conserved hypothetical protein; oxidoreductase 1424277 4796724 llmg_1453 Lactococcus lactis subsp. cremoris MG1363 oxidoreductase YP_001032744.1 1423642 R 416870 CDS YP_001032745.1 125624262 4796702 complement(1424379..1425326) 1 NC_009004.1 ROK_glcA_fam: ROK family protein ( glucokinase), Similar to xylose repressor protein; Specificity unclear; sugar kinase 1425326 4796702 llmg_1454 Lactococcus lactis subsp. cremoris MG1363 sugar kinase YP_001032745.1 1424379 R 416870 CDS YP_001032746.1 125624263 4798171 complement(1425329..1426771) 1 NC_009004.1 Glycoside hydrolase, family 1; High confidence in function and specificity; 6-phospho-beta-glucosidase 1426771 bglA2 4798171 bglA2 Lactococcus lactis subsp. cremoris MG1363 6-phospho-beta-glucosidase YP_001032746.1 1425329 R 416870 CDS YP_001032747.1 125624264 4797229 complement(1426768..1428912) 1 NC_009004.1 Glycoside hydrolase, family 3; High confidence in function and specificity; beta-glucosidase 1428912 bglX 4797229 bglX Lactococcus lactis subsp. cremoris MG1363 beta-glucosidase YP_001032747.1 1426768 R 416870 CDS YP_001032748.1 125624265 4798448 complement(1428989..1430053) 1 NC_009004.1 oligo_HPY: oligopeptide/dipeptide ABC transporter ATP-binding protein; Specificity unclear; di/Tri-peptide transport ATP-binding protein 1430053 4798448 llmg_1457 Lactococcus lactis subsp. cremoris MG1363 di/Tri-peptide transport ATP-binding protein YP_001032748.1 1428989 R 416870 CDS YP_001032749.1 125624266 4799139 complement(1430053..1431072) 1 NC_009004.1 Specificity unclear; di/Tri-peptide transport system permease 1431072 4799139 llmg_1458 Lactococcus lactis subsp. cremoris MG1363 di/Tri-peptide transport system permease YP_001032749.1 1430053 R 416870 CDS YP_001032750.1 125624267 4799111 complement(1431074..1432054) 1 NC_009004.1 Specificity unclear; di/Tri-peptide transport system permease 1432054 4799111 llmg_1459 Lactococcus lactis subsp. cremoris MG1363 di/Tri-peptide transport system permease YP_001032750.1 1431074 R 416870 CDS YP_001032751.1 125624268 4799125 complement(1432054..1433154) 1 NC_009004.1 Specificity unclear; di/Tri-peptide transport ATP-binding protein 1433154 4799125 llmg_1460 Lactococcus lactis subsp. cremoris MG1363 di/Tri-peptide transport ATP-binding protein YP_001032751.1 1432054 R 416870 CDS YP_001032752.1 125624269 4797777 complement(1433227..1434771) 1 NC_009004.1 Specificity unclear; di/Tri-peptide binding protein precursor 1434771 4797777 llmg_1461 Lactococcus lactis subsp. cremoris MG1363 di/Tri-peptide binding protein precursor YP_001032752.1 1433227 R 416870 CDS YP_001032753.1 125624270 4797776 complement(1435163..1435888) 1 NC_009004.1 Contains sugar isomerase (SIS)domain; Family membership; HTH-type transcriptional regulator 1435888 4797776 llmg_1462 Lactococcus lactis subsp. cremoris MG1363 HTH-type transcriptional regulator YP_001032753.1 1435163 R 416870 CDS YP_001032754.1 125624271 4797775 complement(1436035..1437858) 1 NC_009004.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 1437858 lepA 4797775 lepA Lactococcus lactis subsp. cremoris MG1363 GTP-binding protein LepA YP_001032754.1 1436035 R 416870 CDS YP_001032755.1 125624272 4797048 complement(1438148..1438813) 1 NC_009004.1 High confidence in function and specificity; AldC protein 1438813 aldC 4797048 aldC Lactococcus lactis subsp. cremoris MG1363 AldC protein YP_001032755.1 1438148 R 416870 CDS YP_001032756.1 125624273 4797642 1438912..1440261 1 NC_009004.1 High confidence in function and specificity; UDP-N-acetylmuramyl tripeptide synthetase 1440261 murC2 4797642 murC2 Lactococcus lactis subsp. cremoris MG1363 UDP-N-acetylmuramyl tripeptide synthetase YP_001032756.1 1438912 D 416870 CDS YP_001032757.1 125624274 4797423 1440262..1441047 1 NC_009004.1 CobB/CobQ-like glutamine amidotransferase; High confidence in function and specificity; cobyric acid synthase 1441047 cobQ 4797423 cobQ Lactococcus lactis subsp. cremoris MG1363 cobyric acid synthase YP_001032757.1 1440262 D 416870 CDS YP_001032758.1 125624275 4798086 complement(1441125..1443806) 1 NC_009004.1 Similar to ABC-type antimicrobial peptide transport system, permease component; Specificity unclear; ABC transporter permease 1443806 4798086 llmg_1467 Lactococcus lactis subsp. cremoris MG1363 ABC transporter permease YP_001032758.1 1441125 R 416870 CDS YP_001032759.1 125624276 4797774 complement(1443810..1444511) 1 NC_009004.1 Specificity unclear; ABC transporter ATP-binding protein 1444511 4797774 llmg_1468 Lactococcus lactis subsp. cremoris MG1363 ABC transporter ATP-binding protein YP_001032759.1 1443810 R 416870 CDS YP_001032760.1 125624277 4797773 complement(1444713..1445537) 1 NC_009004.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 1445537 nadE 4797773 nadE Lactococcus lactis subsp. cremoris MG1363 NAD synthetase YP_001032760.1 1444713 R 416870 CDS YP_001032761.1 125624278 4797079 complement(1445594..1446082) 1 NC_009004.1 GCN5-related N-acetyltransferase; Family membership; acetyltransferase 1446082 4797079 llmg_1471 Lactococcus lactis subsp. cremoris MG1363 acetyltransferase YP_001032761.1 1445594 R 416870 CDS YP_001032762.1 125624279 4797772 complement(1446079..1447551) 1 NC_009004.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 1447551 pncB 4797772 pncB Lactococcus lactis subsp. cremoris MG1363 nicotinate phosphoribosyltransferase YP_001032762.1 1446079 R 416870 CDS YP_001032763.1 125624280 4799109 1448134..1448727 1 NC_009004.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 1448727 nadD 4799109 nadD Lactococcus lactis subsp. cremoris MG1363 nicotinic acid mononucleotide adenylyltransferase YP_001032763.1 1448134 D 416870 CDS YP_001032764.1 125624281 4798194 complement(1448742..1449953) 1 NC_009004.1 Cl- channel, voltage gated, Voltage gated chloride channel; Specificity unclear; voltage gated chloride channel 1449953 4798194 llmg_1474 Lactococcus lactis subsp. cremoris MG1363 voltage gated chloride channel YP_001032764.1 1448742 R 416870 CDS YP_001032765.1 125624282 4797771 complement(1450356..1450598) 1 NC_009004.1 Bacterial protein of unknown function DUF896; hypothetical protein 1450598 4797771 llmg_1475 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032765.1 1450356 R 416870 CDS YP_001032766.1 125624283 4797769 complement(1450705..1452726) 1 NC_009004.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 1452726 glyS 4797769 glyS Lactococcus lactis subsp. cremoris MG1363 glycyl-tRNA synthetase subunit beta YP_001032766.1 1450705 R 416870 CDS YP_001032767.1 125624284 4798752 complement(1452726..1453679) 1 NC_009004.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 1453679 glyQ 4798752 glyQ Lactococcus lactis subsp. cremoris MG1363 glycyl-tRNA synthetase subunit alpha YP_001032767.1 1452726 R 416870 CDS YP_001032768.1 125624285 4798743 complement(1453908..1454675) 1 NC_009004.1 High confidence in function and specificity; 5'-nucleotidase 1454675 nucA 4798743 nucA Lactococcus lactis subsp. cremoris MG1363 5'-nucleotidase YP_001032768.1 1453908 R 416870 CDS YP_001032769.1 125624286 4798584 complement(1454785..1455804) 1 NC_009004.1 Protein of unknown function DUF475; Conserved hypothetical protein; hypothetical protein 1455804 4798584 llmg_1480 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032769.1 1454785 R 416870 CDS YP_001032770.1 125624287 4797768 complement(1455870..1456370) 1 NC_009004.1 VanZ like protein; Function unclear; teicoplanin resistance protein 1456370 vanZ 4797768 vanZ Lactococcus lactis subsp. cremoris MG1363 teicoplanin resistance protein YP_001032770.1 1455870 R 416870 CDS YP_001032771.1 125624288 4798422 complement(1456412..1457047) 1 NC_009004.1 Protein of unknown function UPF0029; hypothetical protein 1457047 4798422 llmg_1482 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032771.1 1456412 R 416870 CDS YP_001032772.1 125624289 4797767 1457104..1458396 1 NC_009004.1 DEAD/DEAH box helicase, N-terminal, competence protein; Function unclear; superfamily II DNA/RNA helicase 1458396 comFA 4797767 comFA Lactococcus lactis subsp. cremoris MG1363 superfamily II DNA/RNA helicase YP_001032772.1 1457104 D 416870 CDS YP_001032773.1 125624290 4798782 1458396..1459046 1 NC_009004.1 comF: comF family protein, Similar to amidophosphoribosyltransferases; Function unclear; late competence protein 1459046 comFC 4798782 comFC Lactococcus lactis subsp. cremoris MG1363 late competence protein YP_001032773.1 1458396 D 416870 CDS YP_001032774.1 125624291 4798784 complement(1459105..1459683) 1 NC_009004.1 Bacterial protein of unknown function DUF925; hypothetical protein 1459683 4798784 llmg_1485 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032774.1 1459105 R 416870 CDS YP_001032775.1 125624292 4797766 complement(1459700..1460155) 1 NC_009004.1 High confidence in function and specificity; DgkA protein 1460155 dgkA 4797766 dgkA Lactococcus lactis subsp. cremoris MG1363 DgkA protein YP_001032775.1 1459700 R 416870 CDS YP_001032776.1 125624293 4798899 complement(1460139..1460627) 1 NC_009004.1 Protein of unknown function UPF0054; metalloprotease 1460627 4798899 llmg_1487 Lactococcus lactis subsp. cremoris MG1363 metalloprotease YP_001032776.1 1460139 R 416870 CDS YP_001032777.1 125624294 4797765 complement(1460857..1461345) 1 NC_009004.1 contains NUDIX domain; Family membership; hydrolase 1461345 4797765 llmg_1488 Lactococcus lactis subsp. cremoris MG1363 hydrolase YP_001032777.1 1460857 R 416870 CDS YP_001032778.1 125624295 4797762 complement(1461415..1462383) 1 NC_009004.1 phosphate starvation inducible protein; High confidence in function and specificity; PhoH-like protein 1462383 phoH 4797762 phoH Lactococcus lactis subsp. cremoris MG1363 PhoH-like protein YP_001032778.1 1461415 R 416870 CDS YP_001032779.1 125624296 4798552 complement(1462457..1463989) 1 NC_009004.1 nramp: NRAMP family Mn2+/Fe2+ transporters; High confidence in function and specificity; proton-dependent manganese transporter group C beta 1463989 mntH 4798552 mntH Lactococcus lactis subsp. cremoris MG1363 proton-dependent manganese transporter group C beta YP_001032779.1 1462457 R 416870 CDS YP_001032780.1 125624297 4797431 complement(1464261..1464545) 1 NC_009004.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 1464545 rpmA 4797431 rpmA Lactococcus lactis subsp. cremoris MG1363 50S ribosomal protein L27 YP_001032780.1 1464261 R 416870 CDS YP_001032781.1 125624298 4799030 complement(1464547..1464882) 1 NC_009004.1 Protein of unknown function DUF464; hypothetical protein 1464882 4799030 llmg_1492 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032781.1 1464547 R 416870 CDS YP_001032782.1 125624299 4797761 complement(1464885..1465199) 1 NC_009004.1 High confidence in function and specificity; 50S ribosomal protein L21 1465199 rplU 4797761 rplU Lactococcus lactis subsp. cremoris MG1363 50S ribosomal protein L21 YP_001032782.1 1464885 R 416870 CDS YP_001032783.1 125624300 4797845 complement(1465369..1466544) 1 NC_009004.1 Conserved hypothetical protein; ABC transporter permease 1466544 4797845 llmg_1494 Lactococcus lactis subsp. cremoris MG1363 ABC transporter permease YP_001032783.1 1465369 R 416870 CDS YP_001032784.1 125624301 4797760 complement(1466537..1466935) 1 NC_009004.1 hypothetical protein 1466935 4797760 llmg_1495 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032784.1 1466537 R 416870 CDS YP_001032785.1 125624302 4797759 1467108..1468451 1 NC_009004.1 metal-dependent phosphohydrolase, contains HD region; Family membership; phosphohydrolase 1468451 4797759 llmg_1496 Lactococcus lactis subsp. cremoris MG1363 phosphohydrolase YP_001032785.1 1467108 D 416870 CDS YP_001032786.1 125624303 4797758 1468504..1469319 1 NC_009004.1 Cof-subfamily: Cof-like hydrolase; Family membership; hydrolase 1469319 4797758 llmg_1497 Lactococcus lactis subsp. cremoris MG1363 hydrolase YP_001032786.1 1468504 D 416870 CDS YP_001032787.1 125624304 4797757 1469458..1469823 1 NC_009004.1 hypothetical protein 1469823 4797757 llmg_1498 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032787.1 1469458 D 416870 CDS YP_001032788.1 125624305 4797756 complement(1469857..1470630) 1 NC_009004.1 NIF3 (NGG1p interacting factor 3) like protein; hypothetical protein 1470630 4797756 llmg_1499 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032788.1 1469857 R 416870 CDS YP_001032789.1 125624306 4797755 complement(1470627..1471316) 1 NC_009004.1 Similar to SAM-dependent methyltransferases; Conserved hypothetical protein; methyltransferase 1471316 4797755 llmg_1500 Lactococcus lactis subsp. cremoris MG1363 methyltransferase YP_001032789.1 1470627 R 416870 CDS YP_001032790.1 125624307 4797754 complement(1471309..1471965) 1 NC_009004.1 HhH-GPD superfamily base excision DNA repair protein; High confidence in function and specificity; endonuclease III 1471965 nth 4797754 nth Lactococcus lactis subsp. cremoris MG1363 endonuclease III YP_001032790.1 1471309 R 416870 CDS YP_001032791.1 125624308 4796778 complement(1471987..1472655) 1 NC_009004.1 DnaD-like domain; High confidence in function and specificity; DNA replication protein dnaD 1472655 dnaD 4796778 dnaD Lactococcus lactis subsp. cremoris MG1363 DNA replication protein dnaD YP_001032791.1 1471987 R 416870 CDS YP_001032792.1 125624309 4798378 complement(1472921..1475113) 1 NC_009004.1 TIGR02167: Bacterial surface protein 26-residue repeat; Family membership; surface protein 1475113 4798378 llmg_1503 Lactococcus lactis subsp. cremoris MG1363 surface protein YP_001032792.1 1472921 R 416870 CDS YP_001032793.1 125624310 4797753 1475575..1475691 1 NC_009004.1 hypothetical protein 1475691 4797753 llmg_1504 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032793.1 1475575 D 416870 CDS YP_001032794.1 125624311 4797752 complement(1475841..1476767) 1 NC_009004.1 hypothetical protein 1476767 4797752 llmg_1505 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032794.1 1475841 R 416870 CDS YP_001032795.1 125624312 4797751 complement(1476975..1480778) 1 NC_009004.1 SSF49313: cadherin, PF07523.2: Bacterial Ig-like, SSF50447: Translation factor, TIGR01167: Surface protein from Gram-positive cocci, anchor region; hypothetical protein 1480778 4797751 llmg_1506 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032795.1 1476975 R 416870 CDS YP_001032796.1 125624313 4797741 complement(1480957..1482024) 1 NC_009004.1 SM00671: Sel1-like repeat, contains HTH motif; Family membership; hypothetical protein 1482024 4797741 llmg_1507 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032796.1 1480957 R 416870 CDS YP_001032797.1 125624314 4797740 complement(1482282..1483553) 1 NC_009004.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 1483553 pyrC 4797740 pyrC Lactococcus lactis subsp. cremoris MG1363 dihydroorotase YP_001032797.1 1482282 R 416870 CDS YP_001032798.1 125624315 4797637 complement(1483705..1484334) 1 NC_009004.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 1484334 pyrE 4797637 pyrE Lactococcus lactis subsp. cremoris MG1363 orotate phosphoribosyltransferase YP_001032798.1 1483705 R 416870 CDS YP_001032799.1 125624316 4797715 complement(1484827..1486734) 1 NC_009004.1 Function unclear; ABC transporter ATP-binding protein 1486734 4797715 llmg_1512 Lactococcus lactis subsp. cremoris MG1363 ABC transporter ATP-binding protein YP_001032799.1 1484827 R 416870 CDS YP_001032800.1 125624317 4797739 complement(1486907..1487299) 1 NC_009004.1 arsC_related: conserved hypothetical protein, Similar to Regulatory protein spx; hypothetical protein 1487299 4797739 llmg_1513 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032800.1 1486907 R 416870 CDS YP_001032801.1 125624318 4797738 1487522..1488172 1 NC_009004.1 modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor Rex 1488172 rex 4797738 rex Lactococcus lactis subsp. cremoris MG1363 redox-sensing transcriptional repressor Rex YP_001032801.1 1487522 D 416870 CDS YP_001032802.1 125624319 4796930 complement(1488359..1489042) 1 NC_009004.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 1489042 radC 4796930 radC Lactococcus lactis subsp. cremoris MG1363 DNA repair protein RadC YP_001032802.1 1488359 R 416870 CDS YP_001032803.1 125624320 4799102 complement(1489160..1490977) 1 NC_009004.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 1490977 glmS 4799102 glmS Lactococcus lactis subsp. cremoris MG1363 glucosamine--fructose-6-phosphate aminotransferase YP_001032803.1 1489160 R 416870 CDS YP_001032804.1 125624321 4798024 complement(1491159..1491815) 1 NC_009004.1 phosphatidic acid phosphatase 1491815 4798024 llmg_1517 Lactococcus lactis subsp. cremoris MG1363 phosphatidic acid phosphatase YP_001032804.1 1491159 R 416870 CDS YP_001032805.1 125624322 4797737 complement(1491825..1493150) 1 NC_009004.1 High confidence in function and specificity; sensor kinase 1493150 kinE 4797737 kinE Lactococcus lactis subsp. cremoris MG1363 sensor kinase YP_001032805.1 1491825 R 416870 CDS YP_001032806.1 125624323 4796649 complement(1493154..1493669) 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 1493669 4796649 llmg_1519 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032806.1 1493154 R 416870 CDS YP_001032807.1 125624324 4797736 complement(1493690..1494376) 1 NC_009004.1 Response regulator receiver domain; High confidence in function and specificity; two-component system regulator llrE 1494376 llrE 4797736 llrE Lactococcus lactis subsp. cremoris MG1363 two-component system regulator llrE YP_001032807.1 1493690 R 416870 CDS YP_001032808.1 125624325 4796707 complement(1494504..1495460) 1 NC_009004.1 Family membership; glycosyl transferase family protein 1495460 4796707 llmg_1521 Lactococcus lactis subsp. cremoris MG1363 glycosyl transferase family protein YP_001032808.1 1494504 R 416870 CDS YP_001032809.1 125624326 4797750 complement(1495463..1497100) 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 1497100 4797750 llmg_1522 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032809.1 1495463 R 416870 CDS YP_001032810.1 125624327 4797749 complement(1497243..1497686) 1 NC_009004.1 Similar to acid phosphatase/vanadium-dependent haloperoxidases; hypothetical protein 1497686 4797749 llmg_1523 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032810.1 1497243 R 416870 CDS YP_001032811.1 125624328 4797748 complement(1497844..1498749) 1 NC_009004.1 High confidence in function and specificity; ribosomal large subunit pseudouridine synthase D 1498749 rluD 4797748 rluD Lactococcus lactis subsp. cremoris MG1363 ribosomal large subunit pseudouridine synthase D YP_001032811.1 1497844 R 416870 CDS YP_001032812.1 125624329 4796771 complement(1498812..1499264) 1 NC_009004.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 1499264 lspA 4796771 lspA Lactococcus lactis subsp. cremoris MG1363 lipoprotein signal peptidase YP_001032812.1 1498812 R 416870 CDS YP_001032813.1 125624330 4799080 complement(1499553..1499933) 1 NC_009004.1 hypothetical protein 1499933 4799080 llmg_1526 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032813.1 1499553 R 416870 CDS YP_001032814.1 125624331 4797747 1500033..1500431 1 NC_009004.1 Family membership; transcriptional regulator 1500431 4797747 llmg_1527 Lactococcus lactis subsp. cremoris MG1363 transcriptional regulator YP_001032814.1 1500033 D 416870 CDS YP_001032815.1 125624332 4797746 1500713..1500937 1 NC_009004.1 hypothetical protein 1500937 4797746 llmg_1528 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032815.1 1500713 D 416870 CDS YP_001032816.1 125624333 4797745 complement(1501033..1501497) 1 NC_009004.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 1501497 ribH 4797745 ribH Lactococcus lactis subsp. cremoris MG1363 6,7-dimethyl-8-ribityllumazine synthase YP_001032816.1 1501033 R 416870 CDS YP_001032817.1 125624334 4797735 complement(1501524..1502720) 1 NC_009004.1 3,4-dihydroxy-2-butanone 4-phosphate synthase, GTP cyclohydrolase II; High confidence in function and specificity; riboflavin biosynthesis protein ribA 1502720 ribA 4797735 ribA Lactococcus lactis subsp. cremoris MG1363 riboflavin biosynthesis protein ribA YP_001032817.1 1501524 R 416870 CDS YP_001032818.1 125624335 4797066 complement(1502732..1503379) 1 NC_009004.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1503379 ribB 4797066 ribB Lactococcus lactis subsp. cremoris MG1363 riboflavin synthase subunit alpha YP_001032818.1 1502732 R 416870 CDS YP_001032819.1 125624336 4797148 complement(1503379..1504467) 1 NC_009004.1 riboflavin biosynthesis protein RibD 1504467 ribD 4797148 ribD Lactococcus lactis subsp. cremoris MG1363 riboflavin biosynthesis protein RibD YP_001032819.1 1503379 R 416870 CDS YP_001032820.1 125624337 4798233 1504959..1505864 1 NC_009004.1 Mg2+ and Co2+ transporter protein, CorA-like; Conserved hypothetical protein; magnesium and cobalt transport protein 1505864 4798233 llmg_1533 Lactococcus lactis subsp. cremoris MG1363 magnesium and cobalt transport protein YP_001032820.1 1504959 D 416870 CDS YP_001032821.1 125624338 4797734 complement(1505890..1508364) 1 NC_009004.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 1508364 parC 4797734 parC Lactococcus lactis subsp. cremoris MG1363 DNA topoisomerase IV subunit A YP_001032821.1 1505890 R 416870 CDS YP_001032822.1 125624339 4798129 complement(1508689..1509138) 1 NC_009004.1 GCN5-related N-acetyltransferase; Conserved hypothetical protein; ElaA protein 1509138 elaA 4798129 elaA Lactococcus lactis subsp. cremoris MG1363 ElaA protein YP_001032822.1 1508689 R 416870 CDS YP_001032823.1 125624340 4797529 complement(1509135..1509968) 1 NC_009004.1 High confidence in function and specificity; DNA polymerase III subunit epsilon 1509968 dnaQ 4797529 dnaQ Lactococcus lactis subsp. cremoris MG1363 DNA polymerase III subunit epsilon YP_001032823.1 1509135 R 416870 CDS YP_001032824.1 125624341 4798398 complement(1509961..1510542) 1 NC_009004.1 High confidence in function and specificity; isochorismatase 1510542 4798398 llmg_1538 Lactococcus lactis subsp. cremoris MG1363 isochorismatase YP_001032824.1 1509961 R 416870 CDS YP_001032825.1 125624342 4797733 complement(1510604..1512538) 1 NC_009004.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 1512538 parE 4797733 parE Lactococcus lactis subsp. cremoris MG1363 DNA topoisomerase IV subunit B YP_001032825.1 1510604 R 416870 CDS YP_001032826.1 125624343 4798139 1512817..1513458 1 NC_009004.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 1513458 4798139 llmg_1540 Lactococcus lactis subsp. cremoris MG1363 glycerol-3-phosphate acyltransferase PlsY YP_001032826.1 1512817 D 416870 CDS YP_001032827.1 125624344 4798360 1513632..1513850 1 NC_009004.1 High confidence in function and specificity; glutaredoxin-like protein nrdH 1513850 nrdH 4798360 nrdH Lactococcus lactis subsp. cremoris MG1363 glutaredoxin-like protein nrdH YP_001032827.1 1513632 D 416870 CDS YP_001032828.1 125624345 4797260 1513852..1514274 1 NC_009004.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 1514274 nrdI 4797260 nrdI Lactococcus lactis subsp. cremoris MG1363 ribonucleotide reductase stimulatory protein YP_001032828.1 1513852 D 416870 CDS YP_001032829.1 125624346 4797357 1514411..1516579 1 NC_009004.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 1516579 nrdE 4797357 nrdE Lactococcus lactis subsp. cremoris MG1363 ribonucleotide-diphosphate reductase subunit alpha YP_001032829.1 1514411 D 416870 CDS YP_001032830.1 125624347 4797076 1516864..1517841 1 NC_009004.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 1517841 nrdF 4797076 nrdF Lactococcus lactis subsp. cremoris MG1363 ribonucleotide-diphosphate reductase subunit beta YP_001032830.1 1516864 D 416870 CDS YP_001032831.1 125624348 4798066 complement(1517951..1518886) 1 NC_009004.1 High confidence in function and specificity; cell division protein FtsX 1518886 ftsX 4798066 ftsX Lactococcus lactis subsp. cremoris MG1363 cell division protein FtsX YP_001032831.1 1517951 R 416870 CDS YP_001032832.1 125624349 4798846 complement(1518879..1519571) 1 NC_009004.1 High confidence in function and specificity; cell division ATP-binding protein 1519571 ftsE 4798846 ftsE Lactococcus lactis subsp. cremoris MG1363 cell division ATP-binding protein YP_001032832.1 1518879 R 416870 CDS YP_001032833.1 125624350 4799057 complement(1519901..1520998) 1 NC_009004.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 1520998 prfB 4799057 prfB Lactococcus lactis subsp. cremoris MG1363 peptide chain release factor 2 YP_001032833.1 1519901 R 416870 CDS YP_001032834.1 125624351 4798165 1521136..1521723 1 NC_009004.1 Family membership; phosphohydrolase 1521723 4798165 llmg_1548 Lactococcus lactis subsp. cremoris MG1363 phosphohydrolase YP_001032834.1 1521136 D 416870 CDS YP_001032835.1 125624352 4799029 1521871..1522041 1 NC_009004.1 hypothetical protein 1522041 4799029 llmg_1549 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032835.1 1521871 D 416870 CDS YP_001032836.1 125624353 4799028 1522205..1522735 1 NC_009004.1 Protein of unknown function DUF402; hypothetical protein 1522735 4799028 llmg_1550 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032836.1 1522205 D 416870 CDS YP_001032837.1 125624354 4799027 complement(1522750..1523553) 1 NC_009004.1 High confidence in function and specificity; formate dehydrogenase 1523553 fdhC 4799027 fdhC Lactococcus lactis subsp. cremoris MG1363 formate dehydrogenase YP_001032837.1 1522750 R 416870 CDS YP_001032838.1 125624355 4798959 complement(1523708..1525330) 1 NC_009004.1 Specificity unclear; ABC type transport system permease 1525330 4798959 llmg_1552 Lactococcus lactis subsp. cremoris MG1363 ABC type transport system permease YP_001032838.1 1523708 R 416870 CDS YP_001032839.1 125624356 4799026 complement(1525342..1526220) 1 NC_009004.1 Specificity unclear; ABC transporter ATP-binding protein 1526220 4799026 llmg_1553 Lactococcus lactis subsp. cremoris MG1363 ABC transporter ATP-binding protein YP_001032839.1 1525342 R 416870 CDS YP_001032840.1 125624357 4799005 1526416..1527066 1 NC_009004.1 Homeodomain-like; Family membership; TetR family transcriptional regulator 1527066 4799005 llmg_1554 Lactococcus lactis subsp. cremoris MG1363 TetR family transcriptional regulator YP_001032840.1 1526416 D 416870 CDS YP_001032841.1 125624358 4799004 complement(1527099..1528016) 1 NC_009004.1 Protein of unknown function DUF199; hypothetical protein 1528016 4799004 llmg_1555 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032841.1 1527099 R 416870 CDS YP_001032842.1 125624359 4799003 complement(1528112..1529095) 1 NC_009004.1 Conserved hypothetical protein CofD related, Uncharacterised protein family UPF0052; hypothetical protein 1529095 4799003 llmg_1556 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032842.1 1528112 R 416870 CDS YP_001032843.1 125624360 4799002 complement(1529092..1529979) 1 NC_009004.1 Uncharacterised P-loop ATPase UPF0042; Family membership; hypothetical protein 1529979 4799002 llmg_1557 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032843.1 1529092 R 416870 CDS YP_001032844.1 125624361 4799001 complement(1530044..1531489) 1 NC_009004.1 High confidence in function and specificity; cardiolipin synthetase 1531489 clsA 4799001 clsA Lactococcus lactis subsp. cremoris MG1363 cardiolipin synthetase YP_001032844.1 1530044 R 416870 CDS YP_001032845.1 125624362 4798105 complement(1531681..1532370) 1 NC_009004.1 Cyclic nucleotide-binding domain; High confidence in function and specificity; FNR like protein A 1532370 flpA 4798105 flpA Lactococcus lactis subsp. cremoris MG1363 FNR like protein A YP_001032845.1 1531681 R 416870 CDS YP_001032846.1 125624363 4796689 complement(1532360..1532899) 1 NC_009004.1 Ferritin/ribonucleotide reductase-like; Conserved hypothetical protein; stress induced DNA binding protein () 1532899 4796689 llmg_1560 Lactococcus lactis subsp. cremoris MG1363 stress induced DNA binding protein () YP_001032846.1 1532360 R 416870 CDS YP_001032847.1 125624364 4799000 complement(1533121..1534983) 1 NC_009004.1 High confidence in function and specificity; heavy metal-translocating P-type ATPase 1534983 4799000 llmg_1561 Lactococcus lactis subsp. cremoris MG1363 heavy metal-translocating P-type ATPase YP_001032847.1 1533121 R 416870 CDS YP_001032848.1 125624365 4798999 complement(1535617..1536057) 1 NC_009004.1 hypothetical protein 1536057 4798999 llmg_1562 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032848.1 1535617 R 416870 CDS YP_001032849.1 125624366 4798998 complement(1536449..1537783) 1 NC_009004.1 Protein of unknown function DUF805; Conserved hypothetical protein; hypothetical protein 1537783 4798998 llmg_1563 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032849.1 1536449 R 416870 CDS YP_001032850.1 125624367 4798997 1538074..1538364 1 NC_009004.1 transposase helper protein for IS904; High confidence in function and specificity; hypothetical protein 1538364 4798997 llmg_1564 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032850.1 1538074 D 416870 CDS YP_001032851.1 125624368 4798996 1538460..1539221 1 NC_009004.1 Integrase, catalytic region; High confidence in function and specificity; transposase for insertion sequence IS904F 1539221 tnp904 4798996 tnp904 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence IS904F YP_001032851.1 1538460 D 416870 CDS YP_001032852.1 125624369 4797361 1539275..1539856 1 NC_009004.1 High confidence in function and specificity; hypothetical protein 1539856 4797361 llmg_1566 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032852.1 1539275 D 416870 CDS YP_001032853.1 125624370 4796624 complement(1540757..1542661) 1 NC_009004.1 High confidence in function and specificity; PTS system, fructose specific IIBC components 1542661 fruA 4796624 fruA Lactococcus lactis subsp. cremoris MG1363 PTS system, fructose specific IIBC components YP_001032853.1 1540757 R 416870 CDS YP_001032854.1 125624371 4798943 complement(1542661..1543578) 1 NC_009004.1 High confidence in function and specificity; tagatose-6-phosphate kinase 1543578 fruC 4798943 fruC Lactococcus lactis subsp. cremoris MG1363 tagatose-6-phosphate kinase YP_001032854.1 1542661 R 416870 CDS YP_001032855.1 125624372 4797790 complement(1543662..1544363) 1 NC_009004.1 Bacterial regulatory proteins, deoR family; High confidence in function and specificity; lactose transport regulator 1544363 fruR 4797790 fruR Lactococcus lactis subsp. cremoris MG1363 lactose transport regulator YP_001032855.1 1543662 R 416870 CDS YP_001032856.1 125624373 4797339 complement(1544485..1545624) 1 NC_009004.1 High confidence in function and specificity; aminoacylase/N-acyl-L-amino acid amidohydrolase/hippurate hydrolase 1545624 hipO2 4797339 hipO2 Lactococcus lactis subsp. cremoris MG1363 aminoacylase/N-acyl-L-amino acid amidohydrolase/hippurate hydrolase YP_001032856.1 1544485 R 416870 CDS YP_001032857.1 125624374 4798337 complement(1545691..1547454) 1 NC_009004.1 in group A Streptococci this protein was found to cross react with anti myosin antibodies and may play a role in rheumatic fever; hypothetical protein 1547454 mycA 4798337 mycA Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032857.1 1545691 R 416870 CDS YP_001032858.1 125624375 4797063 complement(1547624..1549468) 1 NC_009004.1 Hypothetical 70.0 kDa protein in dnaK 3'region; hypothetical protein 1549468 4797063 llmg_1573 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032858.1 1547624 R 416870 CDS YP_001032859.1 125624376 4798994 complement(1549632..1551455) 1 NC_009004.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 1551455 dnaK 4798994 dnaK Lactococcus lactis subsp. cremoris MG1363 molecular chaperone DnaK YP_001032859.1 1549632 R 416870 CDS YP_001032860.1 125624377 4798395 complement(1551527..1552066) 1 NC_009004.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 1552066 grpE 4798395 grpE Lactococcus lactis subsp. cremoris MG1363 heat shock protein GrpE YP_001032860.1 1551527 R 416870 CDS YP_001032861.1 125624378 4798750 complement(1552096..1553139) 1 NC_009004.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 1553139 hrcA 4798750 hrcA Lactococcus lactis subsp. cremoris MG1363 heat-inducible transcription repressor YP_001032861.1 1552096 R 416870 CDS YP_001032862.1 125624379 4796612 complement(1553287..1553691) 1 NC_009004.1 hypothetical protein 1553691 4796612 llmg_1577 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032862.1 1553287 R 416870 CDS YP_001032863.1 125624380 4798993 complement(1553706..1554452) 1 NC_009004.1 High confidence in function and specificity; D-alanyl-D-alanine carboxypeptidase 1554452 dacB 4798993 dacB Lactococcus lactis subsp. cremoris MG1363 D-alanyl-D-alanine carboxypeptidase YP_001032863.1 1553706 R 416870 CDS YP_001032864.1 125624381 4798872 complement(1554449..1555144) 1 NC_009004.1 High confidence in function and specificity; phosphoglycerate mutase 1555144 gpmB 4798872 gpmB Lactococcus lactis subsp. cremoris MG1363 phosphoglycerate mutase YP_001032864.1 1554449 R 416870 CDS YP_001032865.1 125624382 4798590 complement(1555215..1555694) 1 NC_009004.1 hypothetical protein 1555694 4798590 llmg_1580 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032865.1 1555215 R 416870 CDS YP_001032866.1 125624383 4798992 complement(1555789..1557126) 1 NC_009004.1 Protein of unknown function DUF711; hypothetical protein 1557126 4798992 llmg_1581 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032866.1 1555789 R 416870 CDS YP_001032867.1 125624384 4798991 complement(1557243..1557506) 1 NC_009004.1 ACT domain-containing protein; hypothetical protein 1557506 4798991 llmg_1582 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032867.1 1557243 R 416870 CDS YP_001032868.1 125624385 4798990 1557660..1558601 1 NC_009004.1 Specificity unclear; prenyltransferase 1558601 4798990 llmg_1583 Lactococcus lactis subsp. cremoris MG1363 prenyltransferase YP_001032868.1 1557660 D 416870 CDS YP_001032869.1 125624386 4798989 complement(1558625..1559683) 1 NC_009004.1 Family membership; hypothetical protein 1559683 4798989 llmg_1584 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032869.1 1558625 R 416870 CDS YP_001032870.1 125624387 4798988 complement(1559761..1560348) 1 NC_009004.1 Similar to amidases related to nicotinamidase; Family membership; amidase 1560348 4798988 llmg_1585 Lactococcus lactis subsp. cremoris MG1363 amidase YP_001032870.1 1559761 R 416870 CDS YP_001032871.1 125624388 4798987 complement(1560360..1562819) 1 NC_009004.1 exoribonuclease, VacB/Rnb family; High confidence in function and specificity; exoribonuclease R 1562819 vacB1 4798987 vacB1 Lactococcus lactis subsp. cremoris MG1363 exoribonuclease R YP_001032871.1 1560360 R 416870 CDS YP_001032872.1 125624389 4798437 complement(1563061..1563309) 1 NC_009004.1 Preprotein translocase SecG subunit; High confidence in function and specificity; preprotein translocase subunit SecG 1563309 secG 4798437 secG Lactococcus lactis subsp. cremoris MG1363 preprotein translocase subunit SecG YP_001032872.1 1563061 R 416870 CDS YP_001032873.1 125624390 4798271 complement(1563450..1564376) 1 NC_009004.1 High confidence in function and specificity; TrxB1 protein 1564376 trxB1 4798271 trxB1 Lactococcus lactis subsp. cremoris MG1363 TrxB1 protein YP_001032873.1 1563450 R 416870 CDS YP_001032874.1 125624391 4797152 complement(1564574..1564801) 1 NC_009004.1 hypothetical protein 1564801 4797152 llmg_1589 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032874.1 1564574 R 416870 CDS YP_001032875.1 125624392 4798986 complement(1564803..1565555) 1 NC_009004.1 Specificity unclear; amino-acid ABC transporter ATP-binding protein 1565555 4798986 llmg_1590 Lactococcus lactis subsp. cremoris MG1363 amino-acid ABC transporter ATP-binding protein YP_001032875.1 1564803 R 416870 CDS YP_001032876.1 125624393 4798985 complement(1565567..1566454) 1 NC_009004.1 Specificity unclear; amino-acid ABC transporter permease 1566454 4798985 llmg_1591 Lactococcus lactis subsp. cremoris MG1363 amino-acid ABC transporter permease YP_001032876.1 1565567 R 416870 CDS YP_001032877.1 125624394 4798984 complement(1566722..1567570) 1 NC_009004.1 Specificity unclear; amino acid ABC transporter substrate-binding protein 1567570 4798984 llmg_1593 Lactococcus lactis subsp. cremoris MG1363 amino acid ABC transporter substrate-binding protein YP_001032877.1 1566722 R 416870 CDS YP_001032878.1 125624395 4798983 complement(1567714..1568289) 1 NC_009004.1 Region start changed from 1568256 to 1568289 (33 bases); gamma-glutamyl-diamino acid-endopeptidase 1568289 4798983 llmg_1594 Lactococcus lactis subsp. cremoris MG1363 gamma-glutamyl-diamino acid-endopeptidase YP_001032878.1 1567714 R 416870 CDS YP_001032879.1 125624396 4798982 complement(1568416..1570083) 1 NC_009004.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase 1570083 fhs 4798982 fhs Lactococcus lactis subsp. cremoris MG1363 formate--tetrahydrofolate ligase YP_001032879.1 1568416 R 416870 CDS YP_001032880.1 125624397 4798197 complement(1570244..1570570) 1 NC_009004.1 Protein of unknown function DUF74; hypothetical protein 1570570 4798197 llmg_1596 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032880.1 1570244 R 416870 CDS YP_001032881.1 125624398 4798981 complement(1570654..1571100) 1 NC_009004.1 Protein of unknown function DUF984; hypothetical protein 1571100 4798981 llmg_1597 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032881.1 1570654 R 416870 CDS YP_001032882.1 125624399 4798980 1571714..1572202 1 NC_009004.1 hypothetical protein 1572202 4798980 llmg_1598 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032882.1 1571714 D 416870 CDS YP_001032883.1 125624400 4798979 complement(1572439..1573143) 1 NC_009004.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 1573143 deoD 4798979 deoD Lactococcus lactis subsp. cremoris MG1363 purine nucleoside phosphorylase YP_001032883.1 1572439 R 416870 CDS YP_001032884.1 125624401 4798886 complement(1573214..1573483) 1 NC_009004.1 hypothetical protein 1573483 4798886 llmg_1600 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032884.1 1573214 R 416870 CDS YP_001032885.1 125624402 4798978 complement(1573541..1574776) 1 NC_009004.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 1574776 deoB 4798978 deoB Lactococcus lactis subsp. cremoris MG1363 phosphopentomutase YP_001032885.1 1573541 R 416870 CDS YP_001032886.1 125624403 4798881 complement(1574963..1575793) 1 NC_009004.1 Similar to cell envelope-related transcriptional attenuator lytR; Conserved hypothetical protein; transcriptional regulator 1575793 4798881 llmg_1602 Lactococcus lactis subsp. cremoris MG1363 transcriptional regulator YP_001032886.1 1574963 R 416870 CDS YP_001032887.1 125624404 4798977 complement(1575893..1577008) 1 NC_009004.1 teichoic acid biosynthesis protein B 1577008 tagB 4798977 tagB Lactococcus lactis subsp. cremoris MG1363 teichoic acid biosynthesis protein B YP_001032887.1 1575893 R 416870 CDS YP_001032888.1 125624405 4798736 complement(1576998..1578185) 1 NC_009004.1 CDP-glycerol:glycerophosphate glycerophosphotransferase; High confidence in function and specificity; teichoic acid biosynthesis protein F 1578185 tagF 4798736 tagF Lactococcus lactis subsp. cremoris MG1363 teichoic acid biosynthesis protein F YP_001032888.1 1576998 R 416870 CDS YP_001032889.1 125624406 4798746 complement(1578208..1578639) 1 NC_009004.1 hypothetical protein 1578639 4798746 llmg_1605 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032889.1 1578208 R 416870 CDS YP_001032890.1 125624407 4798976 complement(1578636..1579091) 1 NC_009004.1 High confidence in function and specificity; glycerol-3-phosphate cytidylyltransferase 1579091 tagD2 4798976 tagD2 Lactococcus lactis subsp. cremoris MG1363 glycerol-3-phosphate cytidylyltransferase YP_001032890.1 1578636 R 416870 CDS YP_001032891.1 125624408 4798737 complement(1579142..1580323) 1 NC_009004.1 hypothetical protein 1580323 4798737 llmg_1607 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032891.1 1579142 R 416870 CDS YP_001032892.1 125624409 4798975 complement(1580420..1581421) 1 NC_009004.1 Similar to xylosidases/arabinosidases; Function unclear; glycosyl hydrolases 1581421 4798975 llmg_1608 Lactococcus lactis subsp. cremoris MG1363 glycosyl hydrolases YP_001032892.1 1580420 R 416870 CDS YP_001032893.1 125624410 4798695 complement(1581424..1582710) 1 NC_009004.1 Similar to lipolytic enzymes, G-D-S-L family; Family membership; hypothetical protein 1582710 4798695 llmg_1609 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032893.1 1581424 R 416870 CDS YP_001032894.1 125624411 4796735 1584010..1585233 1 NC_009004.1 Integrase, catalytic region; Specificity unclear; transposase for insertion sequence element IS712G 1585233 tnp712 4796735 tnp712 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS712G YP_001032894.1 1584010 D 416870 CDS YP_001032895.1 125624412 4797570 1585245..1586003 1 NC_009004.1 PF01695: IstB-like ATP-binding protein; Specificity unclear; transposase helper protein for IS712G 1586003 4797570 llmg_1612 Lactococcus lactis subsp. cremoris MG1363 transposase helper protein for IS712G YP_001032895.1 1585245 D 416870 CDS YP_001032896.1 125624413 4798693 complement(1586044..1586841) 1 NC_009004.1 hypothetical protein 1586841 4798693 llmg_1613 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032896.1 1586044 R 416870 CDS YP_001032897.1 125624414 4798692 complement(1586856..1587236) 1 NC_009004.1 hypothetical protein 1587236 4798692 llmg_1614 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032897.1 1586856 R 416870 CDS YP_001032898.1 125624415 4798691 complement(1587246..1587899) 1 NC_009004.1 Family membership; acetyltransferase 1587899 4798691 llmg_1615 Lactococcus lactis subsp. cremoris MG1363 acetyltransferase YP_001032898.1 1587246 R 416870 CDS YP_001032899.1 125624416 4798690 complement(1587913..1589082) 1 NC_009004.1 High confidence in function and specificity; UDP-glucose 6-dehydrogenase 1589082 ugd 4798690 ugd Lactococcus lactis subsp. cremoris MG1363 UDP-glucose 6-dehydrogenase YP_001032899.1 1587913 R 416870 CDS YP_001032900.1 125624417 4798017 complement(1589136..1592123) 1 NC_009004.1 glycosyl transferase, group 2 family protein, Glycosyltransferases involved in cell wall biogenesis; Family membership; hypothetical protein 1592123 4798017 llmg_1617 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032900.1 1589136 R 416870 CDS YP_001032901.1 125624418 4798689 complement(1592144..1593481) 1 NC_009004.1 hypothetical protein 1593481 4798689 llmg_1618 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032901.1 1592144 R 416870 CDS YP_001032902.1 125624419 4798688 complement(1593468..1594496) 1 NC_009004.1 hypothetical protein 1594496 4798688 llmg_1619 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032902.1 1593468 R 416870 CDS YP_001032903.1 125624420 4798687 complement(1594493..1596694) 1 NC_009004.1 glycosyl transferase, group 2 family protein, Glycosyltransferases involved in cell wall biogenesis; Family membership; hypothetical protein 1596694 4798687 llmg_1620 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032903.1 1594493 R 416870 CDS YP_001032904.1 125624421 4798686 complement(1596691..1598169) 1 NC_009004.1 glycosyl transferase, group 2 family protein, Glycosyltransferases involved in cell wall biogenesi; Family membership; hypothetical protein 1598169 4798686 llmg_1621 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032904.1 1596691 R 416870 CDS YP_001032905.1 125624422 4798685 complement(1598186..1598992) 1 NC_009004.1 High confidence in function and specificity; teichoic acid ABC transporter permease 1598992 tagG 4798685 tagG Lactococcus lactis subsp. cremoris MG1363 teichoic acid ABC transporter permease YP_001032905.1 1598186 R 416870 CDS YP_001032906.1 125624423 4798747 complement(1599003..1600433) 1 NC_009004.1 High confidence in function and specificity; teichoic acid export ATP-binding protein tagH 1600433 tagH 4798747 tagH Lactococcus lactis subsp. cremoris MG1363 teichoic acid export ATP-binding protein tagH YP_001032906.1 1599003 R 416870 CDS YP_001032907.1 125624424 4798757 complement(1600496..1601404) 1 NC_009004.1 High confidence in function and specificity; exopolysaccharide biosynthesis protein 1601404 tagL 4798757 tagL Lactococcus lactis subsp. cremoris MG1363 exopolysaccharide biosynthesis protein YP_001032907.1 1600496 R 416870 CDS YP_001032908.1 125624425 4798759 complement(1601728..1602447) 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 1602447 4798759 llmg_1625 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032908.1 1601728 R 416870 CDS YP_001032909.1 125624426 4797429 complement(1603984..1604448) 1 NC_009004.1 Specificity unclear; MarR family transcriptional regulator 1604448 rmaH 4797429 rmaH Lactococcus lactis subsp. cremoris MG1363 MarR family transcriptional regulator YP_001032909.1 1603984 R 416870 CDS YP_001032910.1 125624427 4798040 complement(1604605..1605246) 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 1605246 4798040 llmg_1628 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032910.1 1604605 R 416870 CDS YP_001032911.1 125624428 4798683 complement(1605419..1606156) 1 NC_009004.1 methyltransferase, UbiE/COQ5 family; Family membership; methyltransferase 1606156 4798683 llmg_1629 Lactococcus lactis subsp. cremoris MG1363 methyltransferase YP_001032911.1 1605419 R 416870 CDS YP_001032912.1 125624429 4798682 complement(1606380..1606565) 1 NC_009004.1 hypothetical protein 1606565 4798682 llmg_1630 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032912.1 1606380 R 416870 CDS YP_001032913.1 125624430 4798681 complement(1606663..1608618) 1 NC_009004.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 1608618 gyrB 4798681 gyrB Lactococcus lactis subsp. cremoris MG1363 DNA gyrase subunit B YP_001032913.1 1606663 R 416870 CDS YP_001032914.1 125624431 4797544 complement(1608772..1609419) 1 NC_009004.1 Haloacid dehalogenase-like hydrolase; High confidence in function and specificity; hydrolase 1609419 4797544 llmg_1632 Lactococcus lactis subsp. cremoris MG1363 hydrolase YP_001032914.1 1608772 R 416870 CDS YP_001032915.1 125624432 4798680 complement(1609485..1610330) 1 NC_009004.1 Similar to predicted ring-cleavage extradiol dioxygenase; Family membership; hypothetical protein 1610330 4798680 llmg_1633 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032915.1 1609485 R 416870 CDS YP_001032916.1 125624433 4798679 complement(1610468..1612048) 1 NC_009004.1 Similar to ABC type transport system permease; Conserved hypothetical protein; hypothetical protein 1612048 4798679 llmg_1634 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032916.1 1610468 R 416870 CDS YP_001032917.1 125624434 4798678 complement(1612029..1612793) 1 NC_009004.1 Specificity unclear; ABC transporter ATP-binding protein 1612793 4798678 llmg_1635 Lactococcus lactis subsp. cremoris MG1363 ABC transporter ATP-binding protein YP_001032917.1 1612029 R 416870 CDS YP_001032918.1 125624435 4798677 complement(1612916..1613815) 1 NC_009004.1 TIGRFAM 2A78: Carboxylate/Amino Acid/Amine Transporter; Conserved hypothetical protein; permease 1613815 4798677 llmg_1636 Lactococcus lactis subsp. cremoris MG1363 permease YP_001032918.1 1612916 R 416870 CDS YP_001032919.1 125624436 4798676 complement(1614001..1615278) 1 NC_009004.1 High confidence in function and specificity; malate transporter 1615278 mleP 4798676 mleP Lactococcus lactis subsp. cremoris MG1363 malate transporter YP_001032919.1 1614001 R 416870 CDS YP_001032920.1 125624437 4798616 complement(1615293..1616915) 1 NC_009004.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase 1616915 mleS 4798616 mleS Lactococcus lactis subsp. cremoris MG1363 malate dehydrogenase YP_001032920.1 1615293 R 416870 CDS YP_001032921.1 125624438 4797155 complement(1617330..1618880) 1 NC_009004.1 Similar to lincosamides and streptogramins A transporter Lsa; Specificity unclear; ABC transporter ATP-binding protein 1618880 4797155 llmg_1639 Lactococcus lactis subsp. cremoris MG1363 ABC transporter ATP-binding protein YP_001032921.1 1617330 R 416870 CDS YP_001032922.1 125624439 4798675 complement(1618991..1619152) 1 NC_009004.1 hypothetical protein 1619152 4798675 llmg_1640 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032922.1 1618991 R 416870 CDS YP_001032923.1 125624440 4798674 complement(1619425..1620186) 1 NC_009004.1 High confidence in function and specificity; acetoin reductase 1620186 butA 4798674 butA Lactococcus lactis subsp. cremoris MG1363 acetoin reductase YP_001032923.1 1619425 R 416870 CDS YP_001032924.1 125624441 4797719 complement(1620222..1621202) 1 NC_009004.1 High confidence in function and specificity; 2,3-butanediol dehydrogenase 1621202 butB 4797719 butB Lactococcus lactis subsp. cremoris MG1363 2,3-butanediol dehydrogenase YP_001032924.1 1620222 R 416870 CDS YP_001032925.1 125624442 4797722 complement(1621500..1622744) 1 NC_009004.1 Cell cycle protein; High confidence in function and specificity; rod shape-determining protein RodA 1622744 rodA 4797722 rodA Lactococcus lactis subsp. cremoris MG1363 rod shape-determining protein RodA YP_001032925.1 1621500 R 416870 CDS YP_001032926.1 125624443 4797296 complement(1622956..1623561) 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 1623561 4797296 llmg_1644 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032926.1 1622956 R 416870 CDS YP_001032927.1 125624444 4798673 complement(1623558..1624028) 1 NC_009004.1 polyribonucleotide nucleotidyltransferase, 30S ribosomal protein S1; Function unclear; general stress protein GSP13 1624028 4798673 llmg_1645 Lactococcus lactis subsp. cremoris MG1363 general stress protein GSP13 YP_001032927.1 1623558 R 416870 CDS YP_001032928.1 125624445 4798672 complement(1623991..1624581) 1 NC_009004.1 High confidence in function and specificity; peptidyl-prolyl cis-trans isomerase 1624581 ppiB 4798672 ppiB Lactococcus lactis subsp. cremoris MG1363 peptidyl-prolyl cis-trans isomerase YP_001032928.1 1623991 R 416870 CDS YP_001032929.1 125624446 4796924 complement(1624680..1625486) 1 NC_009004.1 Cof-subfamily: Cof-like hydrolase, Peptidyl-prolyl cis-trans isomerase, cyclophilin type; Family membership; hydrolase 1625486 4796924 llmg_1647 Lactococcus lactis subsp. cremoris MG1363 hydrolase YP_001032929.1 1624680 R 416870 CDS YP_001032930.1 125624447 4798671 complement(1625557..1626186) 1 NC_009004.1 Response regulator receiver domain; High confidence in function and specificity; two-component system regulator llrD 1626186 llrD 4798671 llrD Lactococcus lactis subsp. cremoris MG1363 two-component system regulator llrD YP_001032930.1 1625557 R 416870 CDS YP_001032931.1 125624448 4796745 complement(1626214..1627212) 1 NC_009004.1 Histidine kinase; High confidence in function and specificity; sensor protein kinase kinD 1627212 kinD 4796745 kinD Lactococcus lactis subsp. cremoris MG1363 sensor protein kinase kinD YP_001032931.1 1626214 R 416870 CDS YP_001032932.1 125624449 4797122 complement(1627209..1627784) 1 NC_009004.1 Region start changed from 1627838 to 1627784 (-54 bases); hypothetical protein 1627784 4797122 llmg_1650 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032932.1 1627209 R 416870 CDS YP_001032933.1 125624450 4798670 complement(1628174..1628272) 1 NC_009004.1 hypothetical protein 1628272 4798670 llmg_1651 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032933.1 1628174 R 416870 CDS YP_001032934.1 125624451 4798669 complement(1628988..1629821) 1 NC_009004.1 Similar to predicted ring-cleavage extradiol dioxygenases; hypothetical protein 1629821 4798669 llmg_1652 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032934.1 1628988 R 416870 CDS YP_001032935.1 125624452 4798668 complement(1630153..1631604) 1 NC_009004.1 PF05257.3: CHAP domain; hypothetical protein 1631604 4798668 llmg_1653 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032935.1 1630153 R 416870 CDS YP_001032936.1 125624453 4798667 complement(1631663..1632502) 1 NC_009004.1 Integrase, catalytic region; High confidence in function and specificity; transposase for insertion sequence element IS981M 1632502 tnp981 4798667 tnp981 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS981M YP_001032936.1 1631663 R 416870 CDS YP_001032937.1 125624454 4797923 complement(1632514..1632774) 1 NC_009004.1 transposase helper protein for IS981; High confidence in function and specificity; hypothetical protein 1632774 4797923 llmg_1655 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032937.1 1632514 R 416870 CDS YP_001032938.1 125624455 4798666 1632954..1633292 1 NC_009004.1 hypothetical protein 1633292 4798666 llmg_1656 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032938.1 1632954 D 416870 CDS YP_001032939.1 125624456 4798665 complement(1633481..1634455) 1 NC_009004.1 Similar to phage integrases; High confidence in function and specificity; integrase/recombinase 1634455 xerD 4798665 xerD Lactococcus lactis subsp. cremoris MG1363 integrase/recombinase YP_001032939.1 1633481 R 416870 CDS YP_001032940.1 125624457 4797890 complement(1634590..1634922) 1 NC_009004.1 metal-sulfur cluster biosynthetic enzyme; hypothetical protein 1634922 4797890 llmg_1658 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032940.1 1634590 R 416870 CDS YP_001032941.1 125624458 4798960 complement(1635111..1637510) 1 NC_009004.1 Similar to phage infection protein pip; hypothetical protein 1637510 4798960 llmg_1659 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032941.1 1635111 R 416870 CDS YP_001032942.1 125624459 4798961 1637672..1638205 1 NC_009004.1 Family membership; TetR family transcriptional regulator 1638205 4798961 llmg_1660 Lactococcus lactis subsp. cremoris MG1363 TetR family transcriptional regulator YP_001032942.1 1637672 D 416870 CDS YP_001032943.1 125624460 4798962 complement(1638267..1638572) 1 NC_009004.1 Histone-like bacterial DNA-binding protein; High confidence in function and specificity; HU-like DNA-binding protein 1638572 hslB 4798962 hslB Lactococcus lactis subsp. cremoris MG1363 HU-like DNA-binding protein YP_001032943.1 1638267 R 416870 CDS YP_001032944.1 125624461 4796666 complement(1638797..1639222) 1 NC_009004.1 Universal stress protein family; High confidence in function and specificity; universal stress protein A 1639222 uspA 4796666 uspA Lactococcus lactis subsp. cremoris MG1363 universal stress protein A YP_001032944.1 1638797 R 416870 CDS YP_001032945.1 125624462 4798293 1639477..1639632 1 NC_009004.1 hypothetical protein 1639632 4798293 llmg_1663 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032945.1 1639477 D 416870 CDS YP_001032946.1 125624463 4798963 complement(1639775..1640500) 1 NC_009004.1 High confidence in function and specificity; nicotinamide mononucleotide transporter 1640500 pnuC2 4798963 pnuC2 Lactococcus lactis subsp. cremoris MG1363 nicotinamide mononucleotide transporter YP_001032946.1 1639775 R 416870 CDS YP_001032947.1 125624464 4799056 1640773..1641018 1 NC_009004.1 hypothetical protein 1641018 4799056 llmg_1665 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032947.1 1640773 D 416870 CDS YP_001032948.1 125624465 4798964 complement(1641081..1641638) 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 1641638 4798964 llmg_1666 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032948.1 1641081 R 416870 CDS YP_001032949.1 125624466 4798965 complement(1641869..1643197) 1 NC_009004.1 Glycosyl transferase, family 2, Glycosyltransferases, probably involved in cell wall biogenesis; Specificity unclear; glycosyltransferase 1643197 4798965 llmg_1667 Lactococcus lactis subsp. cremoris MG1363 glycosyltransferase YP_001032949.1 1641869 R 416870 CDS YP_001032950.1 125624467 4798966 complement(1643190..1643381) 1 NC_009004.1 hypothetical protein 1643381 4798966 llmg_1668 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032950.1 1643190 R 416870 CDS YP_001032951.1 125624468 4798967 1643957..1644418 1 NC_009004.1 GCN5-related N-acetyltransferase; acetyltransferase 1644418 4798967 llmg_1669 Lactococcus lactis subsp. cremoris MG1363 acetyltransferase YP_001032951.1 1643957 D 416870 CDS YP_001032952.1 125624469 4798968 1644756..1645172 1 NC_009004.1 Conserved hypothetical protein; ketosteroid isomerase 1645172 4798968 llmg_1670 Lactococcus lactis subsp. cremoris MG1363 ketosteroid isomerase YP_001032952.1 1644756 D 416870 CDS YP_001032953.1 125624470 4798969 complement(1645348..1645692) 1 NC_009004.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1645692 rplS 4798969 rplS Lactococcus lactis subsp. cremoris MG1363 50S ribosomal protein L19 YP_001032953.1 1645348 R 416870 CDS YP_001032954.1 125624471 4797854 complement(1645852..1646526) 1 NC_009004.1 Similar to GTP pyrophosphokinases; High confidence in function and specificity; hypothetical protein 1646526 4797854 llmg_1672 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032954.1 1645852 R 416870 CDS YP_001032955.1 125624472 4798459 complement(1648077..1648964) 1 NC_009004.1 High confidence in function and specificity; malolactic fermentation system transcription activator 1648964 mleR 4798459 mleR Lactococcus lactis subsp. cremoris MG1363 malolactic fermentation system transcription activator YP_001032955.1 1648077 R 416870 CDS YP_001032956.1 125624473 4797524 complement(1649325..1649987) 1 NC_009004.1 Specificity unclear; ABC transporter ATP-binding protein 1649987 4797524 llmg_1675 Lactococcus lactis subsp. cremoris MG1363 ABC transporter ATP-binding protein YP_001032956.1 1649325 R 416870 CDS YP_001032957.1 125624474 4798971 complement(1650095..1651612) 1 NC_009004.1 Protein of unknown function DUF214; Function unclear; ABC transporter permease 1651612 4798971 llmg_1676 Lactococcus lactis subsp. cremoris MG1363 ABC transporter permease YP_001032957.1 1650095 R 416870 CDS YP_001032958.1 125624475 4798972 complement(1651763..1652047) 1 NC_009004.1 hypothetical protein 1652047 4798972 llmg_1677 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032958.1 1651763 R 416870 CDS YP_001032959.1 125624476 4798973 complement(1652246..1653235) 1 NC_009004.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 1653235 mraY 4798973 mraY Lactococcus lactis subsp. cremoris MG1363 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_001032959.1 1652246 R 416870 CDS YP_001032960.1 125624477 4797575 complement(1653310..1655607) 1 NC_009004.1 High confidence in function and specificity; penicillin-binding protein 1655607 pbpX 4797575 pbpX Lactococcus lactis subsp. cremoris MG1363 penicillin-binding protein YP_001032960.1 1653310 R 416870 CDS YP_001032961.1 125624478 4798150 complement(1655604..1655984) 1 NC_009004.1 Conserved hypothetical protein; cell division protein 1655984 ftsL 4798150 ftsL Lactococcus lactis subsp. cremoris MG1363 cell division protein YP_001032961.1 1655604 R 416870 CDS YP_001032962.1 125624479 4798341 complement(1656140..1657093) 1 NC_009004.1 High confidence in function and specificity; S-adenosyl-methyltransferase MraW 1657093 mraW 4798341 mraW Lactococcus lactis subsp. cremoris MG1363 S-adenosyl-methyltransferase MraW YP_001032962.1 1656140 R 416870 CDS YP_001032963.1 125624480 4796863 complement(1657324..1658250) 1 NC_009004.1 Protein of unknown function DUF805; Conserved hypothetical protein; hypothetical protein 1658250 4796863 llmg_1682 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032963.1 1657324 R 416870 CDS YP_001032964.1 125624481 4798974 complement(1658272..1658793) 1 NC_009004.1 Protein of unknown function DUF805; Conserved hypothetical protein; hypothetical protein 1658793 4798974 llmg_1683 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032964.1 1658272 R 416870 CDS YP_001032965.1 125624482 4799017 complement(1658888..1659454) 1 NC_009004.1 Protein of unknown function DUF1211; Conserved hypothetical protein; hypothetical protein 1659454 4799017 llmg_1684 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032965.1 1658888 R 416870 CDS YP_001032966.1 125624483 4798661 complement(1660156..1661823) 1 NC_009004.1 Recombination protein N; High confidence in function and specificity; DNA repair protein recN 1661823 recN 4798661 recN Lactococcus lactis subsp. cremoris MG1363 DNA repair protein recN YP_001032966.1 1660156 R 416870 CDS YP_001032967.1 125624484 4798230 complement(1662003..1662449) 1 NC_009004.1 High confidence in function and specificity; arginine transcriptional regulator 1662449 ahrC 4798230 ahrC Lactococcus lactis subsp. cremoris MG1363 arginine transcriptional regulator YP_001032967.1 1662003 R 416870 CDS YP_001032968.1 125624485 4796703 complement(1662446..1663252) 1 NC_009004.1 Similar to tly, Hemolysin A, Similar to rRNA methylases; hypothetical protein 1663252 4796703 llmg_1687 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032968.1 1662446 R 416870 CDS YP_001032969.1 125624486 4796580 complement(1663328..1663828) 1 NC_009004.1 GCN5-related N-acetyltransferase; Family membership; acetyltransferase 1663828 4796580 llmg_1688 Lactococcus lactis subsp. cremoris MG1363 acetyltransferase YP_001032969.1 1663328 R 416870 CDS YP_001032970.1 125624487 4797409 complement(1663829..1664734) 1 NC_009004.1 geranyltranstransferase 1664734 ispA 4797409 ispA Lactococcus lactis subsp. cremoris MG1363 geranyltranstransferase YP_001032970.1 1663829 R 416870 CDS YP_001032971.1 125624488 4798591 complement(1666225..1666464) 1 NC_009004.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 1666464 xseB 4798591 xseB Lactococcus lactis subsp. cremoris MG1363 exodeoxyribonuclease VII small subunit YP_001032971.1 1666225 R 416870 CDS YP_001032972.1 125624489 4797853 complement(1666467..1667720) 1 NC_009004.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 1667720 xseA 4797853 xseA Lactococcus lactis subsp. cremoris MG1363 exodeoxyribonuclease VII large subunit YP_001032972.1 1666467 R 416870 CDS YP_001032973.1 125624490 4797860 complement(1667891..1668748) 1 NC_009004.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 1668748 folD 4797860 folD Lactococcus lactis subsp. cremoris MG1363 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_001032973.1 1667891 R 416870 CDS YP_001032974.1 125624491 4798056 1668937..1670979 1 NC_009004.1 High confidence in function and specificity; copper-potassium transporting ATPase B 1670979 copB 4798056 copB Lactococcus lactis subsp. cremoris MG1363 copper-potassium transporting ATPase B YP_001032974.1 1668937 D 416870 CDS YP_001032975.1 125624492 4798804 complement(1671055..1671336) 1 NC_009004.1 hypothetical protein 1671336 4798804 llmg_1695 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032975.1 1671055 R 416870 CDS YP_001032976.1 125624493 4797878 complement(1672592..1674109) 1 NC_009004.1 hypothetical protein 1674109 4797878 llmg_1698 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032976.1 1672592 R 416870 CDS YP_001032977.1 125624494 4797983 complement(1674398..1675900) 1 NC_009004.1 High confidence in function and specificity; choline ABC transporter permease and substrate binding protein 1675900 choS 4797983 choS Lactococcus lactis subsp. cremoris MG1363 choline ABC transporter permease and substrate binding protein YP_001032977.1 1674398 R 416870 CDS YP_001032978.1 125624495 4798179 complement(1675897..1676814) 1 NC_009004.1 High confidence in function and specificity; choline ABC transporter ATP binding protein 1676814 choQ 4798179 choQ Lactococcus lactis subsp. cremoris MG1363 choline ABC transporter ATP binding protein YP_001032978.1 1675897 R 416870 CDS YP_001032979.1 125624496 4796962 1676817..1676960 1 NC_009004.1 hypothetical protein 1676960 4796962 llmg_1701 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032979.1 1676817 D 416870 CDS YP_001032980.1 125624497 4798320 complement(1676943..1678250) 1 NC_009004.1 High confidence in function and specificity; glutathione reductase 1678250 gshR 4798320 gshR Lactococcus lactis subsp. cremoris MG1363 glutathione reductase YP_001032980.1 1676943 R 416870 CDS YP_001032981.1 125624498 4798755 complement(1678389..1678817) 1 NC_009004.1 Similar to regulatory protein spx; Family membership; hypothetical protein 1678817 4798755 llmg_1703 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032981.1 1678389 R 416870 CDS YP_001032982.1 125624499 4796695 complement(1678978..1680081) 1 NC_009004.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 1680081 alr 4796695 alr Lactococcus lactis subsp. cremoris MG1363 alanine racemase YP_001032982.1 1678978 R 416870 CDS YP_001032983.1 125624500 4797682 complement(1680125..1680484) 1 NC_009004.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 1680484 acpS 4797682 acpS Lactococcus lactis subsp. cremoris MG1363 4'-phosphopantetheinyl transferase YP_001032983.1 1680125 R 416870 CDS YP_001032984.1 125624501 4798910 complement(1680613..1682031) 1 NC_009004.1 divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases; dipeptidase PepV 1682031 pepV 4798910 pepV Lactococcus lactis subsp. cremoris MG1363 dipeptidase PepV YP_001032984.1 1680613 R 416870 CDS YP_001032985.1 125624502 4796786 1682785..1683171 1 NC_009004.1 Conserved hypothetical protein; glycosyltransferase 1683171 4796786 llmg_1707 Lactococcus lactis subsp. cremoris MG1363 glycosyltransferase YP_001032985.1 1682785 D 416870 CDS YP_001032986.1 125624503 4797980 complement(1683885..1685078) 1 NC_009004.1 Similar to Lipopolysaccharide 1,2- glucosyltransferases; Family membership; glycosyltransferase 1685078 4797980 llmg_1708 Lactococcus lactis subsp. cremoris MG1363 glycosyltransferase YP_001032986.1 1683885 R 416870 CDS YP_001032987.1 125624504 4798454 complement(1685283..1685765) 1 NC_009004.1 High confidence in function and specificity; maltose O-acetyltransferase 1685765 maa2 4798454 maa2 Lactococcus lactis subsp. cremoris MG1363 maltose O-acetyltransferase YP_001032987.1 1685283 R 416870 CDS YP_001032988.1 125624505 4797167 complement(1685949..1686839) 1 NC_009004.1 Glycosyltransferases involved in cell wall biogenesis; Family membership; glycosyltransferase 1686839 4797167 llmg_1710 Lactococcus lactis subsp. cremoris MG1363 glycosyltransferase YP_001032988.1 1685949 R 416870 CDS YP_001032989.1 125624506 4797848 complement(1688183..1689022) 1 NC_009004.1 Integrase, catalytic region; High confidence in function and specificity; transposase for insertion sequence element IS981N 1689022 tnp981 4797848 tnp981 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS981N YP_001032989.1 1688183 R 416870 CDS YP_001032990.1 125624507 4797922 complement(1689034..1689294) 1 NC_009004.1 transposase helper protein for IS981; Specificity unclear; hypothetical protein 1689294 4797922 llmg_1714 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032990.1 1689034 R 416870 CDS YP_001032991.1 125624508 4797403 1689454..1689744 1 NC_009004.1 transposase helper protein for IS904; hypothetical protein 1689744 4797403 llmg_1715 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032991.1 1689454 D 416870 CDS YP_001032992.1 125624509 4797406 1689840..1690601 1 NC_009004.1 Integrase, catalytic region; High confidence in function and specificity; transposase for insertion sequence IS904G 1690601 tnp904 4797406 tnp904 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence IS904G YP_001032992.1 1689840 D 416870 CDS YP_001032993.1 125624510 4796733 complement(1691590..1692750) 1 NC_009004.1 High confidence in function and specificity; A/G-specific adenine glycosylase 1692750 mutY 4796733 mutY Lactococcus lactis subsp. cremoris MG1363 A/G-specific adenine glycosylase YP_001032993.1 1691590 R 416870 CDS YP_001032994.1 125624511 4796774 complement(1692848..1694857) 1 NC_009004.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 1694857 uvrC 4796774 uvrC Lactococcus lactis subsp. cremoris MG1363 excinuclease ABC subunit C YP_001032994.1 1692848 R 416870 CDS YP_001032995.1 125624512 4797324 complement(1694953..1695666) 1 NC_009004.1 High confidence in function and specificity; PnuC1 protein 1695666 pnuC1 4797324 pnuC1 Lactococcus lactis subsp. cremoris MG1363 PnuC1 protein YP_001032995.1 1694953 R 416870 CDS YP_001032996.1 125624513 4799058 complement(1695684..1696400) 1 NC_009004.1 High confidence in function and specificity; uridine phosphorylase 1696400 udp 4799058 udp Lactococcus lactis subsp. cremoris MG1363 uridine phosphorylase YP_001032996.1 1695684 R 416870 CDS YP_001032997.1 125624514 4796710 complement(1698612..1700063) 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 1700063 4796710 llmg_1723 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001032997.1 1698612 R 416870 CDS YP_001032998.1 125624515 4798321 complement(1700259..1701485) 1 NC_009004.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1701485 rpsA 4798321 rpsA Lactococcus lactis subsp. cremoris MG1363 30S ribosomal protein S1 YP_001032998.1 1700259 R 416870 CDS YP_001032999.1 125624516 4799019 complement(1701740..1702894) 1 NC_009004.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1702894 mnmA 4799019 mnmA Lactococcus lactis subsp. cremoris MG1363 tRNA-specific 2-thiouridylase MnmA YP_001032999.1 1701740 R 416870 CDS YP_001033000.1 125624517 4797445 1703183..1703968 1 NC_009004.1 High confidence in function and specificity; galactose-1-phosphate uridylyltransferase 1703968 4797445 llmg_1726 Lactococcus lactis subsp. cremoris MG1363 galactose-1-phosphate uridylyltransferase YP_001033000.1 1703183 D 416870 CDS YP_001033001.1 125624518 4798319 1704039..1706690 1 NC_009004.1 Conserved hypothetical protein; ABC transporter permease 1706690 4798319 llmg_1727 Lactococcus lactis subsp. cremoris MG1363 ABC transporter permease YP_001033001.1 1704039 D 416870 CDS YP_001033002.1 125624519 4797396 1706680..1706826 1 NC_009004.1 hypothetical protein 1706826 4797396 llmg_1728 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033002.1 1706680 D 416870 CDS YP_001033003.1 125624520 4797389 complement(1706892..1709054) 1 NC_009004.1 High confidence in function and specificity; copper/potassium-transporting ATPase 1709054 copA 4797389 copA Lactococcus lactis subsp. cremoris MG1363 copper/potassium-transporting ATPase YP_001033003.1 1706892 R 416870 CDS YP_001033004.1 125624521 4798803 complement(1709241..1709441) 1 NC_009004.1 TIGR00003: copper ion binding protein; High confidence in function and specificity; mercuric reductase 1709441 merP 4798803 merP Lactococcus lactis subsp. cremoris MG1363 mercuric reductase YP_001033004.1 1709241 R 416870 CDS YP_001033005.1 125624522 4798331 complement(1709460..1709915) 1 NC_009004.1 High confidence in function and specificity; transcriptional regulator 1709915 copR 4798331 copR Lactococcus lactis subsp. cremoris MG1363 transcriptional regulator YP_001033005.1 1709460 R 416870 CDS YP_001033006.1 125624523 4798808 complement(1710037..1710900) 1 NC_009004.1 High confidence in function and specificity; L-serine dehydratase alpha subunit 1710900 sdaA 4798808 sdaA Lactococcus lactis subsp. cremoris MG1363 L-serine dehydratase alpha subunit YP_001033006.1 1710037 R 416870 CDS YP_001033007.1 125624524 4798927 complement(1710920..1711591) 1 NC_009004.1 High confidence in function and specificity; L-serine dehydratase beta subunit 1711591 sdaB 4798927 sdaB Lactococcus lactis subsp. cremoris MG1363 L-serine dehydratase beta subunit YP_001033007.1 1710920 R 416870 CDS YP_001033008.1 125624525 4798272 complement(1711705..1713708) 1 NC_009004.1 High confidence in function and specificity; NADH dehydrogenase 1713708 noxB 4798272 noxB Lactococcus lactis subsp. cremoris MG1363 NADH dehydrogenase YP_001033008.1 1711705 R 416870 CDS YP_001033009.1 125624526 4797065 complement(1713852..1715111) 1 NC_009004.1 High confidence in function and specificity; NADH dehydrogenase 1715111 noxA 4797065 noxA Lactococcus lactis subsp. cremoris MG1363 NADH dehydrogenase YP_001033009.1 1713852 R 416870 CDS YP_001033010.1 125624527 4799101 complement(1715242..1715604) 1 NC_009004.1 hypothetical protein 1715604 4799101 llmg_1736 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033010.1 1715242 R 416870 CDS YP_001033011.1 125624528 4797988 complement(1715764..1716567) 1 NC_009004.1 High confidence in function and specificity; non-heme chloride peroxidase 1716567 cpo 4797988 cpo Lactococcus lactis subsp. cremoris MG1363 non-heme chloride peroxidase YP_001033011.1 1715764 R 416870 CDS YP_001033012.1 125624529 4798816 complement(1716819..1718180) 1 NC_009004.1 High confidence in function and specificity; beta-glucosidase 1718180 4798816 llmg_1738 Lactococcus lactis subsp. cremoris MG1363 beta-glucosidase YP_001033012.1 1716819 R 416870 CDS YP_001033013.1 125624530 4797425 complement(1720098..1720853) 1 NC_009004.1 LacI-family regulatory protein; Family membership; HTH-type transcriptional regulator 1720853 4797425 llmg_1740 Lactococcus lactis subsp. cremoris MG1363 HTH-type transcriptional regulator YP_001033013.1 1720098 R 416870 CDS YP_001033014.1 125624531 4797994 complement(1721185..1723674) 1 NC_009004.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 1723674 leuS 4797994 leuS Lactococcus lactis subsp. cremoris MG1363 leucyl-tRNA synthetase YP_001033014.1 1721185 R 416870 CDS YP_001033015.1 125624532 4796671 complement(1723745..1724416) 1 NC_009004.1 contains Fis-type Helix-turn-helix domain; Conserved hypothetical protein; regulator 1724416 4796671 llmg_1742 Lactococcus lactis subsp. cremoris MG1363 regulator YP_001033015.1 1723745 R 416870 CDS YP_001033016.1 125624533 4798038 complement(1724489..1725463) 1 NC_009004.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1725463 prsA 4798038 prsA Lactococcus lactis subsp. cremoris MG1363 ribose-phosphate pyrophosphokinase YP_001033016.1 1724489 R 416870 CDS YP_001033017.1 125624534 4798494 complement(1725640..1727019) 1 NC_009004.1 High confidence in function and specificity; signal recognition particle-docking protein 1727019 ftsY 4798494 ftsY Lactococcus lactis subsp. cremoris MG1363 signal recognition particle-docking protein YP_001033017.1 1725640 R 416870 CDS YP_001033018.1 125624535 4798651 complement(1727081..1727632) 1 NC_009004.1 hypothetical protein 1727632 4798651 llmg_1745 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033018.1 1727081 R 416870 CDS YP_001033019.1 125624536 4797395 complement(1727642..1728451) 1 NC_009004.1 Cof-subfamily: Cof-like hydrolase; Conserved hypothetical protein; hydrolase 1728451 4797395 llmg_1746 Lactococcus lactis subsp. cremoris MG1363 hydrolase YP_001033019.1 1727642 R 416870 CDS YP_001033020.1 125624537 4797618 1728858..1730168 1 NC_009004.1 Family membership; amino acid permease 1730168 4797618 llmg_1747 Lactococcus lactis subsp. cremoris MG1363 amino acid permease YP_001033020.1 1728858 D 416870 CDS YP_001033021.1 125624538 4797380 complement(1730218..1730979) 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 1730979 4797380 llmg_1748 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033021.1 1730218 R 416870 CDS YP_001033022.1 125624539 4797995 complement(1730976..1732094) 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 1732094 4797995 llmg_1749 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033022.1 1730976 R 416870 CDS YP_001033023.1 125624540 4797982 complement(1732185..1732595) 1 NC_009004.1 hypothetical protein 1732595 4797982 llmg_1750 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033023.1 1732185 R 416870 CDS YP_001033024.1 125624541 4797977 complement(1732686..1734854) 1 NC_009004.1 Conserved hypothetical protein; alkaline phosphatase 1734854 4797977 llmg_1751 Lactococcus lactis subsp. cremoris MG1363 alkaline phosphatase YP_001033024.1 1732686 R 416870 CDS YP_001033025.1 125624542 4797410 complement(1735096..1738620) 1 NC_009004.1 High confidence in function and specificity; chromosome segregation protein smc 1738620 smc 4797410 smc Lactococcus lactis subsp. cremoris MG1363 chromosome segregation protein smc YP_001033025.1 1735096 R 416870 CDS YP_001033026.1 125624543 4797743 complement(1738610..1739305) 1 NC_009004.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 1739305 rnc 4797743 rnc Lactococcus lactis subsp. cremoris MG1363 ribonuclease III YP_001033026.1 1738610 R 416870 CDS YP_001033027.1 125624544 4798050 complement(1739480..1740481) 1 NC_009004.1 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase 1740481 argF 4798050 argF Lactococcus lactis subsp. cremoris MG1363 ornithine carbamoyltransferase YP_001033027.1 1739480 R 416870 CDS YP_001033028.1 125624545 4798089 complement(1740509..1741360) 1 NC_009004.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 1741360 argB 4798089 argB Lactococcus lactis subsp. cremoris MG1363 acetylglutamate kinase YP_001033028.1 1740509 R 416870 CDS YP_001033029.1 125624546 4797969 complement(1741357..1742490) 1 NC_009004.1 High confidence in function and specificity; acetylornithine aminotransferase 1742490 argD 4797969 argD Lactococcus lactis subsp. cremoris MG1363 acetylornithine aminotransferase YP_001033029.1 1741357 R 416870 CDS YP_001033030.1 125624547 4798473 complement(1742503..1743693) 1 NC_009004.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase 1743693 argJ 4798473 argJ Lactococcus lactis subsp. cremoris MG1363 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase YP_001033030.1 1742503 R 416870 CDS YP_001033031.1 125624548 4799150 complement(1743705..1744727) 1 NC_009004.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 1744727 argC 4799150 argC Lactococcus lactis subsp. cremoris MG1363 N-acetyl-gamma-glutamyl-phosphate reductase YP_001033031.1 1743705 R 416870 CDS YP_001033032.1 125624549 4798016 complement(1744868..1745500) 1 NC_009004.1 Family membership; NADH-flavin reductase 1745500 4798016 llmg_1759 Lactococcus lactis subsp. cremoris MG1363 NADH-flavin reductase YP_001033032.1 1744868 R 416870 CDS YP_001033033.1 125624550 4797382 complement(1745604..1746113) 1 NC_009004.1 Protein of unknown function DUF988; hypothetical protein 1746113 4797382 llmg_1760 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033033.1 1745604 R 416870 CDS YP_001033034.1 125624551 4797401 1746125..1746241 1 NC_009004.1 hypothetical protein 1746241 4797401 llmg_1761 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033034.1 1746125 D 416870 CDS YP_001033035.1 125624552 4797984 complement(1746516..1747247) 1 NC_009004.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1747247 fabG 4797984 fabG Lactococcus lactis subsp. cremoris MG1363 3-ketoacyl-ACP reductase YP_001033035.1 1746516 R 416870 CDS YP_001033036.1 125624553 4797398 complement(1747264..1747503) 1 NC_009004.1 hypothetical protein 1747503 4797398 llmg_1763 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033036.1 1747264 R 416870 CDS YP_001033037.1 125624554 4797402 complement(1748021..1750009) 1 NC_009004.1 High confidence in function and specificity; MetS protein 1750009 metS 4797402 metS Lactococcus lactis subsp. cremoris MG1363 MetS protein YP_001033037.1 1748021 R 416870 CDS YP_001033038.1 125624555 4798900 1750191..1751048 1 NC_009004.1 exodeoxyribonuclease A; High confidence in function and specificity; 3'-exo-deoxyribonuclease 1751048 exoA 4798900 exoA Lactococcus lactis subsp. cremoris MG1363 3'-exo-deoxyribonuclease YP_001033038.1 1750191 D 416870 CDS YP_001033039.1 125624556 4797415 1751137..1751694 1 NC_009004.1 GCN5-related N-acetyltransferase; High confidence in function and specificity; acetyltransferase 1751694 4797415 llmg_1766 Lactococcus lactis subsp. cremoris MG1363 acetyltransferase YP_001033039.1 1751137 D 416870 CDS YP_001033040.1 125624557 4797992 1751946..1752530 1 NC_009004.1 High confidence in function and specificity; DeoR family transcriptional regulator 1752530 rdrA 4797992 rdrA Lactococcus lactis subsp. cremoris MG1363 DeoR family transcriptional regulator YP_001033040.1 1751946 D 416870 CDS YP_001033041.1 125624558 4796590 complement(1752697..1753047) 1 NC_009004.1 Similar to regulatory protein spx; Family membership; hypothetical protein 1753047 4796590 llmg_1768 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033041.1 1752697 R 416870 CDS YP_001033042.1 125624559 4797408 complement(1753123..1753377) 1 NC_009004.1 Protein of unknown function DUF156; hypothetical protein 1753377 4797408 llmg_1769 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033042.1 1753123 R 416870 CDS YP_001033043.1 125624560 4798111 complement(1753404..1755047) 1 NC_009004.1 High confidence in function and specificity; NADH oxidase 1755047 noxC 4798111 noxC Lactococcus lactis subsp. cremoris MG1363 NADH oxidase YP_001033043.1 1753404 R 416870 CDS YP_001033044.1 125624561 4797039 complement(1755044..1755352) 1 NC_009004.1 Contains rhodanese-like domain; Conserved hypothetical protein; rhodanese-related sulfurtransferase 1755352 4797039 llmg_1771 Lactococcus lactis subsp. cremoris MG1363 rhodanese-related sulfurtransferase YP_001033044.1 1755044 R 416870 CDS YP_001033045.1 125624562 4797390 complement(1755363..1755740) 1 NC_009004.1 Contains Rhodanese-like domain; Conserved hypothetical protein; rhodanese-related sulfurtransferase 1755740 4797390 llmg_1772 Lactococcus lactis subsp. cremoris MG1363 rhodanese-related sulfurtransferase YP_001033045.1 1755363 R 416870 CDS YP_001033046.1 125624563 4796755 complement(1755797..1756036) 1 NC_009004.1 CsbD-like protein; hypothetical protein 1756036 4796755 llmg_1773 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033046.1 1755797 R 416870 CDS YP_001033047.1 125624564 4797400 complement(1756038..1756130) 1 NC_009004.1 hypothetical protein 1756130 4797400 llmg_1774 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033047.1 1756038 R 416870 CDS YP_001033048.1 125624565 4797411 complement(1756264..1757184) 1 NC_009004.1 cysteine synthase; High confidence in function and specificity; O-acetylserine sulfhydrylase 1757184 cysK 4797411 cysK Lactococcus lactis subsp. cremoris MG1363 O-acetylserine sulfhydrylase YP_001033048.1 1756264 R 416870 CDS YP_001033049.1 125624566 4798866 complement(1757399..1758541) 1 NC_009004.1 catalyzes the formation of L-cystathionine from O-succinyl-L-homoserine and L-cysteine; or Cystathionine beta-lyase (CBL) can convert cystathionine to homocysteine; cystathionine gamma-synthase 1758541 metC 4798866 metC Lactococcus lactis subsp. cremoris MG1363 cystathionine gamma-synthase YP_001033049.1 1757399 R 416870 CDS YP_001033050.1 125624567 4798868 complement(1758672..1759466) 1 NC_009004.1 High confidence in function and specificity; AccA protein 1759466 accA 4798868 accA Lactococcus lactis subsp. cremoris MG1363 AccA protein YP_001033050.1 1758672 R 416870 CDS YP_001033051.1 125624568 4796842 complement(1759459..1760325) 1 NC_009004.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 1760325 accD 4796842 accD Lactococcus lactis subsp. cremoris MG1363 acetyl-CoA carboxylase subunit beta YP_001033051.1 1759459 R 416870 CDS YP_001033052.1 125624569 4798865 complement(1760411..1761778) 1 NC_009004.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 1761778 accC 4798865 accC Lactococcus lactis subsp. cremoris MG1363 acetyl-CoA carboxylase biotin carboxylase subunit YP_001033052.1 1760411 R 416870 CDS YP_001033053.1 125624570 4798855 complement(1761771..1761953) 1 NC_009004.1 hypothetical protein 1761953 4798855 llmg_1780 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033053.1 1761771 R 416870 CDS YP_001033054.1 125624571 4798455 complement(1762172..1762606) 1 NC_009004.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 1762606 fabZ 4798455 fabZ Lactococcus lactis subsp. cremoris MG1363 (3R)-hydroxymyristoyl-ACP dehydratase YP_001033054.1 1762172 R 416870 CDS YP_001033055.1 125624572 4797581 complement(1762733..1763200) 1 NC_009004.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 1763200 accB 4797581 accB Lactococcus lactis subsp. cremoris MG1363 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_001033055.1 1762733 R 416870 CDS YP_001033056.1 125624573 4796577 complement(1763207..1764436) 1 NC_009004.1 High confidence in function and specificity; 3-oxoacyl-ACP synthase 1764436 fabF 4796577 fabF Lactococcus lactis subsp. cremoris MG1363 3-oxoacyl-ACP synthase YP_001033056.1 1763207 R 416870 CDS YP_001033057.1 125624574 4799130 complement(1764477..1765208) 1 NC_009004.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1765208 fabG 4799130 fabG Lactococcus lactis subsp. cremoris MG1363 3-ketoacyl-ACP reductase YP_001033057.1 1764477 R 416870 CDS YP_001033058.1 125624575 4796708 complement(1765337..1766257) 1 NC_009004.1 High confidence in function and specificity; malonyl CoA-acyl carrier protein transacylase 1766257 fabD 4796708 fabD Lactococcus lactis subsp. cremoris MG1363 malonyl CoA-acyl carrier protein transacylase YP_001033058.1 1765337 R 416870 CDS YP_001033059.1 125624576 4797480 complement(1766543..1766764) 1 NC_009004.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1766764 acpP 4797480 acpP Lactococcus lactis subsp. cremoris MG1363 acyl carrier protein YP_001033059.1 1766543 R 416870 CDS YP_001033060.1 125624577 4798894 complement(1766945..1767922) 1 NC_009004.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 1767922 fabH 4798894 fabH Lactococcus lactis subsp. cremoris MG1363 3-oxoacyl-ACP synthase YP_001033060.1 1766945 R 416870 CDS YP_001033061.1 125624578 4796594 complement(1767922..1768362) 1 NC_009004.1 High confidence in function and specificity; MarR family transcriptional regulator 1768362 rmaG 4796594 rmaG Lactococcus lactis subsp. cremoris MG1363 MarR family transcriptional regulator YP_001033061.1 1767922 R 416870 CDS YP_001033062.1 125624579 4798063 complement(1768769..1769716) 1 NC_009004.1 High confidence in function and specificity; mannose-6-phosphate isomerase 1769716 pmi 4798063 pmi Lactococcus lactis subsp. cremoris MG1363 mannose-6-phosphate isomerase YP_001033062.1 1768769 R 416870 CDS YP_001033063.1 125624580 4797801 1769704..1769883 1 NC_009004.1 hypothetical protein 1769883 4797801 llmg_1790 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033063.1 1769704 D 416870 CDS YP_001033064.1 125624581 4797384 complement(1769892..1770251) 1 NC_009004.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 1770251 rbfA 4797384 rbfA Lactococcus lactis subsp. cremoris MG1363 ribosome-binding factor A YP_001033064.1 1769892 R 416870 CDS YP_001033065.1 125624582 4796800 complement(1770497..1773349) 1 NC_009004.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 1773349 infB 4796800 infB Lactococcus lactis subsp. cremoris MG1363 translation initiation factor IF-2 YP_001033065.1 1770497 R 416870 CDS YP_001033066.1 125624583 4797652 complement(1773370..1773675) 1 NC_009004.1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; Conserved hypothetical protein; hypothetical protein 1773675 4797652 llmg_1793 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033066.1 1773370 R 416870 CDS YP_001033067.1 125624584 4797405 complement(1773678..1774004) 1 NC_009004.1 Protein of unknown function DUF448., Predicted nucleic-acid-binding protein implicated in transcription termination; hypothetical protein 1774004 4797405 llmg_1794 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033067.1 1773678 R 416870 CDS YP_001033068.1 125624585 4797407 complement(1774170..1775318) 1 NC_009004.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 1775318 nusA 4797407 nusA Lactococcus lactis subsp. cremoris MG1363 transcription elongation factor NusA YP_001033068.1 1774170 R 416870 CDS YP_001033069.1 125624586 4796861 complement(1775486..1775959) 1 NC_009004.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 1775959 4796861 llmg_1797 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033069.1 1775486 R 416870 CDS YP_001033070.1 125624587 4797999 1776233..1776637 1 NC_009004.1 export of murein hydrolases; Conserved hypothetical protein; LrgA family protein 1776637 lrgA 4797999 lrgA Lactococcus lactis subsp. cremoris MG1363 LrgA family protein YP_001033070.1 1776233 D 416870 CDS YP_001033071.1 125624588 4797617 1776656..1777354 1 NC_009004.1 effector of murein hydrolase; Conserved hypothetical protein; LrgB family protein 1777354 lrgB 4797617 lrgB Lactococcus lactis subsp. cremoris MG1363 LrgB family protein YP_001033071.1 1776656 D 416870 CDS YP_001033072.1 125624589 4796677 complement(1777419..1778129) 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 1778129 4796677 llmg_1800 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033072.1 1777419 R 416870 CDS YP_001033073.1 125624590 4797391 complement(1778143..1779432) 1 NC_009004.1 High confidence in function and specificity; sortase 1779432 srtC 4797391 srtC Lactococcus lactis subsp. cremoris MG1363 sortase YP_001033073.1 1778143 R 416870 CDS YP_001033074.1 125624591 4798581 complement(1779483..1781306) 1 NC_009004.1 Contains Cna B-type domain (PF05738.2); hypothetical protein 1781306 4798581 llmg_1802 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033074.1 1779483 R 416870 CDS YP_001033075.1 125624592 4797393 complement(1781422..1784949) 1 NC_009004.1 Surface protein from Gram-positive cocci, anchor region; Family membership; hypothetical protein 1784949 4797393 llmg_1803 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033075.1 1781422 R 416870 CDS YP_001033076.1 125624593 4797616 complement(1785382..1786230) 1 NC_009004.1 Transcriptional regulator Rgg/GadR/MutR family; Family membership; Rgg family transcriptional regulator 1786230 4797616 llmg_1804 Lactococcus lactis subsp. cremoris MG1363 Rgg family transcriptional regulator YP_001033076.1 1785382 R 416870 CDS YP_001033077.1 125624594 4797379 complement(1786335..1787645) 1 NC_009004.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 1787645 engA 4797379 engA Lactococcus lactis subsp. cremoris MG1363 GTP-binding protein EngA YP_001033077.1 1786335 R 416870 CDS YP_001033078.1 125624595 4798363 complement(1787757..1788272) 1 NC_009004.1 Region start changed from 1788440 to 1788272 (-168 bases); hypothetical protein 1788272 4798363 llmg_1806 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033078.1 1787757 R 416870 CDS YP_001033079.1 125624596 4797997 complement(1788380..1789102) 1 NC_009004.1 Family membership; nitroreductase 1789102 4797997 llmg_1807 Lactococcus lactis subsp. cremoris MG1363 nitroreductase YP_001033079.1 1788380 R 416870 CDS YP_001033080.1 125624597 4798453 complement(1789095..1789976) 1 NC_009004.1 Primosomal protein that may act to load helicase DnaC during DNA replication; primosomal protein DnaI 1789976 dnaI 4798453 dnaI Lactococcus lactis subsp. cremoris MG1363 primosomal protein DnaI YP_001033080.1 1789095 R 416870 CDS YP_001033081.1 125624598 4798390 complement(1789976..1791151) 1 NC_009004.1 High confidence in function and specificity; chromosome replication initiation / membrane attachment protein 1791151 dnaB 4798390 dnaB Lactococcus lactis subsp. cremoris MG1363 chromosome replication initiation / membrane attachment protein YP_001033081.1 1789976 R 416870 CDS YP_001033082.1 125624599 4798374 complement(1791234..1791680) 1 NC_009004.1 Protein of unknown function DUF193, Contains ATP- cone domain PF03477; Conserved hypothetical protein; transcriptional regulator NrdR 1791680 nrdR 4798374 nrdR Lactococcus lactis subsp. cremoris MG1363 transcriptional regulator NrdR YP_001033082.1 1791234 R 416870 CDS YP_001033083.1 125624600 4797998 complement(1791868..1792521) 1 NC_009004.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 1792521 trmB 4797998 trmB Lactococcus lactis subsp. cremoris MG1363 tRNA (guanine-N(7)-)-methyltransferase YP_001033083.1 1791868 R 416870 CDS YP_001033084.1 125624601 4797989 complement(1792647..1793420) 1 NC_009004.1 Phosphotransferase enzyme family, Similar to choline kinases involved in LPS biosynthesis; kinase 1793420 4797989 llmg_1812 Lactococcus lactis subsp. cremoris MG1363 kinase YP_001033084.1 1792647 R 416870 CDS YP_001033085.1 125624602 4797394 complement(1793489..1793746) 1 NC_009004.1 Protein of unknown function DUF1021; hypothetical protein 1793746 4797394 llmg_1813 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033085.1 1793489 R 416870 CDS YP_001033086.1 125624603 4797404 complement(1793972..1795339) 1 NC_009004.1 High confidence in function and specificity; DnaC protein 1795339 dnaC 4797404 dnaC Lactococcus lactis subsp. cremoris MG1363 DnaC protein YP_001033086.1 1793972 R 416870 CDS YP_001033087.1 125624604 4798375 complement(1795345..1795797) 1 NC_009004.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 1795797 rplI 4798375 rplI Lactococcus lactis subsp. cremoris MG1363 50S ribosomal protein L9 YP_001033087.1 1795345 R 416870 CDS YP_001033088.1 125624605 4797927 complement(1795794..1797758) 1 NC_009004.1 Phosphoesterase, RecJ-like, DHH family; Conserved hypothetical protein; RecJ-like protein 1797758 4797927 llmg_1816 Lactococcus lactis subsp. cremoris MG1363 RecJ-like protein YP_001033088.1 1795794 R 416870 CDS YP_001033089.1 125624606 4797392 complement(1797851..1798555) 1 NC_009004.1 Family membership; beta-phosphoglucomutase 1798555 4797392 llmg_1817 Lactococcus lactis subsp. cremoris MG1363 beta-phosphoglucomutase YP_001033089.1 1797851 R 416870 CDS YP_001033090.1 125624607 4798315 1798647..1799129 1 NC_009004.1 High confidence in function and specificity; MarR family transcriptional regulator 1799129 rmaA 4798315 rmaA Lactococcus lactis subsp. cremoris MG1363 MarR family transcriptional regulator YP_001033090.1 1798647 D 416870 CDS YP_001033091.1 125624608 4798469 1799113..1799976 1 NC_009004.1 patatin like protein; hypothetical protein 1799976 4798469 llmg_1819 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033091.1 1799113 D 416870 CDS YP_001033092.1 125624609 4798458 1800198..1801550 1 NC_009004.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; aspartate kinase 1801550 thrA 4798458 thrA Lactococcus lactis subsp. cremoris MG1363 aspartate kinase YP_001033092.1 1800198 D 416870 CDS YP_001033093.1 125624610 4796986 complement(1801588..1801770) 1 NC_009004.1 Similar to C terminal of FloL, flotilin like protein; hypothetical protein 1801770 4796986 llmg_1821 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033093.1 1801588 R 416870 CDS YP_001033094.1 125624611 4797987 complement(1801934..1803322) 1 NC_009004.1 Cof-subfamily: Cof-like hydrolase; hypothetical protein 1803322 4797987 llmg_1822 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033094.1 1801934 R 416870 CDS YP_001033095.1 125624612 4798318 1803517..1804485 1 NC_009004.1 High confidence in function and specificity; L-asparaginase 1804485 ansB 4798318 ansB Lactococcus lactis subsp. cremoris MG1363 L-asparaginase YP_001033095.1 1803517 D 416870 CDS YP_001033096.1 125624613 4799136 complement(1804462..1804557) 1 NC_009004.1 hypothetical protein 1804557 4799136 llmg_1824 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033096.1 1804462 R 416870 CDS YP_001033097.1 125624614 4797981 complement(1804587..1805510) 1 NC_009004.1 PF01368.8: Phosphoesterase, RecJ-like, PF02272.6: Phosphoesterase, DHHA1; hypothetical protein 1805510 4797981 llmg_1825 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033097.1 1804587 R 416870 CDS YP_001033098.1 125624615 4797985 complement(1805605..1806885) 1 NC_009004.1 PF00571.15: contains CBS domain; Family membership; hypothetical protein 1806885 4797985 llmg_1826 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033098.1 1805605 R 416870 CDS YP_001033099.1 125624616 4797976 complement(1806892..1807473) 1 NC_009004.1 GCN5-related N-acetyltransferase; Family membership; acetyltransferase 1807473 4797976 llmg_1827 Lactococcus lactis subsp. cremoris MG1363 acetyltransferase YP_001033099.1 1806892 R 416870 CDS YP_001033100.1 125624617 4797388 1807726..1808877 1 NC_009004.1 High confidence in function and specificity; menaquinone-specific isochorismate synthase 1808877 menF 4797388 menF Lactococcus lactis subsp. cremoris MG1363 menaquinone-specific isochorismate synthase YP_001033100.1 1807726 D 416870 CDS YP_001033101.1 125624618 4797539 1808919..1810583 1 NC_009004.1 2-oxoglutarate decarboxylase 1810583 menD 4797539 menD Lactococcus lactis subsp. cremoris MG1363 2-oxoglutarate decarboxylase YP_001033101.1 1808919 D 416870 CDS YP_001033102.1 125624619 4797549 1810573..1811388 1 NC_009004.1 contains alpha/beta hydrolase fold; High confidence in function and specificity; menaquinone biosynthesis-like protein 1811388 menX 4797549 menX Lactococcus lactis subsp. cremoris MG1363 menaquinone biosynthesis-like protein YP_001033102.1 1810573 D 416870 CDS YP_001033103.1 125624620 4797588 1811711..1812553 1 NC_009004.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase 1812553 menB 4797588 menB Lactococcus lactis subsp. cremoris MG1363 naphthoate synthase YP_001033103.1 1811711 D 416870 CDS YP_001033104.1 125624621 4797587 1812710..1814065 1 NC_009004.1 High confidence in function and specificity; O-succinylbenzoic acid--CoA ligase 1814065 menE 4797587 menE Lactococcus lactis subsp. cremoris MG1363 O-succinylbenzoic acid--CoA ligase YP_001033104.1 1812710 D 416870 CDS YP_001033105.1 125624622 4797543 1814062..1815174 1 NC_009004.1 High confidence in function and specificity; o-succinylbenzoate synthase 1815174 menC 4797543 menC Lactococcus lactis subsp. cremoris MG1363 o-succinylbenzoate synthase YP_001033105.1 1814062 D 416870 CDS YP_001033106.1 125624623 4797564 1815577..1815987 1 NC_009004.1 Phenylacetic acid degradation-related protein; hypothetical protein 1815987 4797564 llmg_1834 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033106.1 1815577 D 416870 CDS YP_001033107.1 125624624 4797007 complement(1815995..1816984) 1 NC_009004.1 transcriptional regulator, LacI family; High confidence in function and specificity; LacI family transcriptional regulator 1816984 rliC 4797007 rliC Lactococcus lactis subsp. cremoris MG1363 LacI family transcriptional regulator YP_001033107.1 1815995 R 416870 CDS YP_001033108.1 125624625 4796679 complement(1817071..1819290) 1 NC_009004.1 Glycoside hydrolase, family 31; High confidence in function and specificity; alpha-xylosidase 1819290 xylS 4796679 xylS Lactococcus lactis subsp. cremoris MG1363 alpha-xylosidase YP_001033108.1 1817071 R 416870 CDS YP_001033109.1 125624626 4798938 complement(1819317..1819958) 1 NC_009004.1 Protein of unknown function DUF624; Family membership; hypothetical protein 1819958 4798938 llmg_1837 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033109.1 1819317 R 416870 CDS YP_001033110.1 125624627 4797991 complement(1820036..1821598) 1 NC_009004.1 Family membership; sugar ABC transporter substrate-binding protein 1821598 4797991 llmg_1838 Lactococcus lactis subsp. cremoris MG1363 sugar ABC transporter substrate-binding protein YP_001033110.1 1820036 R 416870 CDS YP_001033111.1 125624628 4797990 complement(1821661..1822275) 1 NC_009004.1 Family membership; sugar ABC transporter permease 1822275 4797990 llmg_1839 Lactococcus lactis subsp. cremoris MG1363 sugar ABC transporter permease YP_001033111.1 1821661 R 416870 CDS YP_001033112.1 125624629 4798457 complement(1822453..1823292) 1 NC_009004.1 Integrase, catalytic region; High confidence in function and specificity; transposase for insertion sequence element IS981O 1823292 tnp981 4798457 tnp981 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS981O YP_001033112.1 1822453 R 416870 CDS YP_001033113.1 125624630 4797904 complement(1823304..1823564) 1 NC_009004.1 transposase helper protein for IS981; hypothetical protein 1823564 4797904 llmg_1841 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033113.1 1823304 R 416870 CDS YP_001033114.1 125624631 4797399 1823644..1823748 1 NC_009004.1 SSF56349: DNA breaking-rejoining enzyme, catalytic core, fragment; hypothetical protein 1823748 4797399 llmg_1842 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033114.1 1823644 D 416870 CDS YP_001033115.1 125624632 4797996 complement(1824296..1824763) 1 NC_009004.1 cytidine/deoxycytidylate deaminase; hypothetical protein 1824763 4797996 llmg_1843 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033115.1 1824296 R 416870 CDS YP_001033116.1 125624633 4798322 complement(1824764..1825702) 1 NC_009004.1 PF00149.13: Metallophosphoesterase; hypothetical protein 1825702 4798322 llmg_1844 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033116.1 1824764 R 416870 CDS YP_001033117.1 125624634 4797381 complement(1825690..1826442) 1 NC_009004.1 PF00753.14: Beta-lactamase-like; Family membership; metal-dependent hydrolase 1826442 4797381 llmg_1845 Lactococcus lactis subsp. cremoris MG1363 metal-dependent hydrolase YP_001033117.1 1825690 R 416870 CDS YP_001033118.1 125624635 4797397 complement(1826765..1826965) 1 NC_009004.1 Cold-shock protein, DNA-binding, 'Cold-shock' DNA- binding domain; Conserved hypothetical protein; cold shock-like protein cspB 1826965 cspB 4797397 cspB Lactococcus lactis subsp. cremoris MG1363 cold shock-like protein cspB YP_001033118.1 1826765 R 416870 CDS YP_001033119.1 125624636 4798821 complement(1827234..1827434) 1 NC_009004.1 Nucleic acid-binding OB-fold, 'Cold-shock' DNA- binding domain; Conserved hypothetical protein; cold shock-like protein cspA 1827434 cspA 4798821 cspA Lactococcus lactis subsp. cremoris MG1363 cold shock-like protein cspA YP_001033119.1 1827234 R 416870 CDS YP_001033120.1 125624637 4798820 complement(1827557..1827757) 1 NC_009004.1 hypothetical protein 1827757 4798820 llmg_1848 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033120.1 1827557 R 416870 CDS YP_001033121.1 125624638 4798175 complement(1828098..1829207) 1 NC_009004.1 High confidence in function and specificity; hypothetical protein 1829207 metE2 4798175 metE2 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033121.1 1828098 R 416870 CDS YP_001033122.1 125624639 4798878 1829375..1830361 1 NC_009004.1 Zinc-containing alcohol dehydrogenase superfamily; High confidence in function and specificity; quinone oxidoreductase 1830361 qor 4798878 qor Lactococcus lactis subsp. cremoris MG1363 quinone oxidoreductase YP_001033122.1 1829375 D 416870 CDS YP_001033123.1 125624640 4798415 complement(1830390..1831052) 1 NC_009004.1 Protein of unknown function DUF1275; Conserved hypothetical protein; hypothetical protein 1831052 4798415 llmg_1851 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033123.1 1830390 R 416870 CDS YP_001033124.1 125624641 4797978 1831263..1831481 1 NC_009004.1 SSF53056: Carbonic anhydrase, prokaryotic and plant; hypothetical protein 1831481 4797978 llmg_1852 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033124.1 1831263 D 416870 CDS YP_001033125.1 125624642 4797993 1831548..1833542 1 NC_009004.1 Protein of unknown function DUF214; Family membership; ABC transporter ATP-binding and permease 1833542 4797993 llmg_1853 Lactococcus lactis subsp. cremoris MG1363 ABC transporter ATP-binding and permease YP_001033125.1 1831548 D 416870 CDS YP_001033126.1 125624643 4797386 1833817..1834461 1 NC_009004.1 PF00597.8: DedA family protein; High confidence in function and specificity; alkaline phosphatase 1834461 apl 4797386 apl Lactococcus lactis subsp. cremoris MG1363 alkaline phosphatase YP_001033126.1 1833817 D 416870 CDS YP_001033127.1 125624644 4798947 1834775..1835149 1 NC_009004.1 hypothetical protein 1835149 4798947 llmg_1855 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033127.1 1834775 D 416870 CDS YP_001033128.1 125624645 4797383 complement(1835166..1836938) 1 NC_009004.1 High confidence in function and specificity; multidrug resistance ABC transporter ATP-binding protein/permease 1836938 lmrA 4797383 lmrA Lactococcus lactis subsp. cremoris MG1363 multidrug resistance ABC transporter ATP-binding protein/permease YP_001033128.1 1835166 R 416870 CDS YP_001033129.1 125624646 4797647 complement(1837030..1837368) 1 NC_009004.1 Conserved hypothetical protein; esterase 1837368 4797647 llmg_1857 Lactococcus lactis subsp. cremoris MG1363 esterase YP_001033129.1 1837030 R 416870 CDS YP_001033130.1 125624647 4796791 complement(1837720..1838208) 1 NC_009004.1 Conserved hypothetical protein; flavodoxin 1838208 4796791 llmg_1859 Lactococcus lactis subsp. cremoris MG1363 flavodoxin YP_001033130.1 1837720 R 416870 CDS YP_001033131.1 125624648 4797387 complement(1838235..1839122) 1 NC_009004.1 High confidence in function and specificity; MarR family transcriptional regulator 1839122 rmaB 4797387 rmaB Lactococcus lactis subsp. cremoris MG1363 MarR family transcriptional regulator YP_001033131.1 1838235 R 416870 CDS YP_001033132.1 125624649 4797221 complement(1839456..1841177) 1 NC_009004.1 involved in the cytochrome D branch of aerobic respiration; High confidence in function and specificity; cytochrome D ABC transporter ATP binding and permease 1841177 cydD 4797221 cydD Lactococcus lactis subsp. cremoris MG1363 cytochrome D ABC transporter ATP binding and permease YP_001033132.1 1839456 R 416870 CDS YP_001033133.1 125624650 4798856 complement(1841177..1842952) 1 NC_009004.1 involved in the cytochrome D branch of aerobic respiration; High confidence in function and specificity; cytochrome D ABC transporter ATP binding and permease 1842952 cydC 4798856 cydC Lactococcus lactis subsp. cremoris MG1363 cytochrome D ABC transporter ATP binding and permease YP_001033133.1 1841177 R 416870 CDS YP_001033134.1 125624651 4798853 complement(1843151..1844146) 1 NC_009004.1 High confidence in function and specificity; cytochrome d ubiquinol oxidase, subunit II 1844146 cydB 4798853 cydB Lactococcus lactis subsp. cremoris MG1363 cytochrome d ubiquinol oxidase, subunit II YP_001033134.1 1843151 R 416870 CDS YP_001033135.1 125624652 4798851 complement(1844146..1845621) 1 NC_009004.1 High confidence in function and specificity; cytochrome bd-I ubiquinol oxidase subunit I 1845621 cydA 4798851 cydA Lactococcus lactis subsp. cremoris MG1363 cytochrome bd-I ubiquinol oxidase subunit I YP_001033135.1 1844146 R 416870 CDS YP_001033136.1 125624653 4798848 complement(1846343..1847836) 1 NC_009004.1 POT family protein; High confidence in function and specificity; di-/tripeptide transporter 1847836 dtpT 4798848 dtpT Lactococcus lactis subsp. cremoris MG1363 di-/tripeptide transporter YP_001033136.1 1846343 R 416870 CDS YP_001033137.1 125624654 4798393 complement(1848372..1848671) 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 1848671 4798393 llmg_1866 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033137.1 1848372 R 416870 CDS YP_001033138.1 125624655 4797385 complement(1848710..1848859) 1 NC_009004.1 contains Bacteriocin-type signal sequence; hypothetical protein 1848859 4797385 llmg_1867 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033138.1 1848710 R 416870 CDS YP_001033139.1 125624656 4796982 complement(1848959..1849216) 1 NC_009004.1 Family membership; HTH-type transcriptional regulator 1849216 4796982 llmg_1868 Lactococcus lactis subsp. cremoris MG1363 HTH-type transcriptional regulator YP_001033139.1 1848959 R 416870 CDS YP_001033140.1 125624657 4797986 complement(1849292..1851094) 1 NC_009004.1 amylopullulanase 1851094 apu 4797986 apu Lactococcus lactis subsp. cremoris MG1363 amylopullulanase YP_001033140.1 1849292 R 416870 CDS YP_001033141.1 125624658 4797056 1851191..1851337 1 NC_009004.1 hypothetical protein 1851337 4797056 llmg_1870 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033141.1 1851191 D 416870 CDS YP_001033142.1 125624659 4796756 complement(1851324..1853726) 1 NC_009004.1 PF00343.8: Glycosyl transferase, family 35, P_ylase: glycogen/starch/alpha-glucan phosphorylases; High confidence in function and specificity; glycogen phosphorylase 1853726 glgP 4796756 glgP Lactococcus lactis subsp. cremoris MG1363 glycogen phosphorylase YP_001033142.1 1851324 R 416870 CDS YP_001033143.1 125624660 4798517 complement(1853810..1855282) 1 NC_009004.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 1855282 glgA 4798517 glgA Lactococcus lactis subsp. cremoris MG1363 glycogen synthase YP_001033143.1 1853810 R 416870 CDS YP_001033144.1 125624661 4796915 complement(1855336..1856475) 1 NC_009004.1 High confidence in function and specificity; glucose-1-phosphate adenylyltransferase 1856475 glgD 4796915 glgD Lactococcus lactis subsp. cremoris MG1363 glucose-1-phosphate adenylyltransferase YP_001033144.1 1855336 R 416870 CDS YP_001033145.1 125624662 4797208 complement(1856465..1857607) 1 NC_009004.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 1857607 glgC 4797208 glgC Lactococcus lactis subsp. cremoris MG1363 glucose-1-phosphate adenylyltransferase YP_001033145.1 1856465 R 416870 CDS YP_001033146.1 125624663 4798601 complement(1861256..1862233) 1 NC_009004.1 N utilization substance protein B homolog (NusB protein); High confidence in function and specificity; transcription termination protein nusB 1862233 nusB 4798601 nusB Lactococcus lactis subsp. cremoris MG1363 transcription termination protein nusB YP_001033146.1 1861256 R 416870 CDS YP_001033147.1 125624664 4798598 complement(1862226..1862627) 1 NC_009004.1 Protein of unknown function DUF322; hypothetical protein 1862627 4798598 llmg_1879 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033147.1 1862226 R 416870 CDS YP_001033148.1 125624665 4796721 complement(1862774..1863331) 1 NC_009004.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 1863331 efp 4796721 efp Lactococcus lactis subsp. cremoris MG1363 elongation factor P YP_001033148.1 1862774 R 416870 CDS YP_001033149.1 125624666 4798751 complement(1863463..1864521) 1 NC_009004.1 metallopeptidase M24; High confidence in function and specificity; aminopeptidase 1864521 pepP 4798751 pepP Lactococcus lactis subsp. cremoris MG1363 aminopeptidase YP_001033149.1 1863463 R 416870 CDS YP_001033150.1 125624667 4796867 complement(1864629..1865513) 1 NC_009004.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 1865513 ksgA 4796867 ksgA Lactococcus lactis subsp. cremoris MG1363 dimethyladenosine transferase YP_001033150.1 1864629 R 416870 CDS YP_001033151.1 125624668 4797620 complement(1865644..1866204) 1 NC_009004.1 primaseG_like: primase-related protein, TIGR00334; High confidence in function and specificity; hypothetical protein 1866204 4797620 llmg_1883 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033151.1 1865644 R 416870 CDS YP_001033152.1 125624669 4796812 complement(1866182..1866715) 1 NC_009004.1 COG0563: Adenylate kinase and related kinases [Enterococcus faecium]; DNA topology modulation protein FlaR 1866715 flaR 4796812 flaR Lactococcus lactis subsp. cremoris MG1363 DNA topology modulation protein FlaR YP_001033152.1 1866182 R 416870 CDS YP_001033153.1 125624670 4796902 complement(1866749..1867522) 1 NC_009004.1 TatD-related deoxyribonuclease, TIGR00010: hydrolase, TatD family; High confidence in function and specificity; deoxyribonuclease 1867522 tatD 4796902 tatD Lactococcus lactis subsp. cremoris MG1363 deoxyribonuclease YP_001033153.1 1866749 R 416870 CDS YP_001033154.1 125624671 4798760 complement(1867667..1868806) 1 NC_009004.1 DNA breaking-rejoining enzyme, catalytic core; Conserved hypothetical protein; IntTn5276 protein 1868806 intTn5276 4798760 intTn5276 Lactococcus lactis subsp. cremoris MG1363 IntTn5276 protein YP_001033154.1 1867667 R 416870 CDS YP_001033155.1 125624672 4796628 complement(1868889..1869122) 1 NC_009004.1 N-terminal 10aa extension to Tn5276 excisionase in L. lactis reported in database.[alternative start point (ttg)]; Tn5276 excisionase 1869122 xisTn5276 4796628 xisTn5276 Lactococcus lactis subsp. cremoris MG1363 Tn5276 excisionase YP_001033155.1 1868889 R 416870 CDS YP_001033156.1 125624673 4797932 complement(1869149..1869640) 1 NC_009004.1 Conserved hypothetical protein; ArdA protein 1869640 ardA 4797932 ardA Lactococcus lactis subsp. cremoris MG1363 ArdA protein YP_001033156.1 1869149 R 416870 CDS YP_001033157.1 125624674 4796871 complement(1869664..1870158) 1 NC_009004.1 hypothetical protein 1870158 4796871 llmg_1889 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033157.1 1869664 R 416870 CDS YP_001033158.1 125624675 4796809 complement(1870253..1870531) 1 NC_009004.1 CHAP family similarity although does not contain the invariant Cys,His residues; hypothetical protein 1870531 isp2 4796809 isp2 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033158.1 1870253 R 416870 CDS YP_001033159.1 125624676 4798523 1872289..1873050 1 NC_009004.1 Conserved hypothetical protein; transposase for insertion sequence IS904H 1873050 tnp904 4798523 tnp904 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence IS904H YP_001033159.1 1872289 D 416870 CDS YP_001033160.1 125624677 4798170 1873268..1873849 1 NC_009004.1 Similar to phosphoglycerate/bisphosphoglycerate mutases; High confidence in function and specificity; phosphoglycerate mutase 1873849 4798170 llmg_1894 Lactococcus lactis subsp. cremoris MG1363 phosphoglycerate mutase YP_001033160.1 1873268 D 416870 CDS YP_001033161.1 125624678 4796817 complement(1873877..1874530) 1 NC_009004.1 Conserved hypothetical protein; phosphate transport system regulator phoU 1874530 phoU 4796817 phoU Lactococcus lactis subsp. cremoris MG1363 phosphate transport system regulator phoU YP_001033161.1 1873877 R 416870 CDS YP_001033162.1 125624679 4796635 complement(1874773..1875534) 1 NC_009004.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 1875534 pstA 4796635 pstA Lactococcus lactis subsp. cremoris MG1363 phosphate transporter ATP-binding protein YP_001033162.1 1874773 R 416870 CDS YP_001033163.1 125624680 4797870 complement(1875742..1876551) 1 NC_009004.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 1876551 pstB 4797870 pstB Lactococcus lactis subsp. cremoris MG1363 phosphate transporter ATP-binding protein YP_001033163.1 1875742 R 416870 CDS YP_001033164.1 125624681 4797868 complement(1876584..1877477) 1 NC_009004.1 Conserved hypothetical protein; phosphate ABC transporter permease 1877477 pstC 4797868 pstC Lactococcus lactis subsp. cremoris MG1363 phosphate ABC transporter permease YP_001033164.1 1876584 R 416870 CDS YP_001033165.1 125624682 4797852 complement(1877477..1878400) 1 NC_009004.1 Conserved hypothetical protein; phosphate ABC transporter permease 1878400 pstD 4797852 pstD Lactococcus lactis subsp. cremoris MG1363 phosphate ABC transporter permease YP_001033165.1 1877477 R 416870 CDS YP_001033166.1 125624683 4797846 complement(1878541..1879392) 1 NC_009004.1 Conserved hypothetical protein; phosphate transport substrate binding protein pstE 1879392 pstE 4797846 pstE Lactococcus lactis subsp. cremoris MG1363 phosphate transport substrate binding protein pstE YP_001033166.1 1878541 R 416870 CDS YP_001033167.1 125624684 4797782 complement(1879732..1880628) 1 NC_009004.1 Conserved hypothetical protein; phosphate transport substrate binding protein pstF 1880628 pstF 4797782 pstF Lactococcus lactis subsp. cremoris MG1363 phosphate transport substrate binding protein pstF YP_001033167.1 1879732 R 416870 CDS YP_001033168.1 125624685 4797783 complement(1880841..1881308) 1 NC_009004.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 1881308 smpB 4797783 smpB Lactococcus lactis subsp. cremoris MG1363 SsrA-binding protein YP_001033168.1 1880841 R 416870 CDS YP_001033169.1 125624686 4796685 complement(1881373..1881675) 1 NC_009004.1 Protein of unknown function DUF24; Conserved hypothetical protein; transcriptional regulator 1881675 4796685 llmg_1903 Lactococcus lactis subsp. cremoris MG1363 transcriptional regulator YP_001033169.1 1881373 R 416870 CDS YP_001033170.1 125624687 4797001 1881777..1882388 1 NC_009004.1 Similar to NAD(P)H nitroreductases; High confidence in function and specificity; nitroreductase 1882388 4797001 llmg_1904 Lactococcus lactis subsp. cremoris MG1363 nitroreductase YP_001033170.1 1881777 D 416870 CDS YP_001033171.1 125624688 4798534 complement(1882378..1882941) 1 NC_009004.1 GDSL-like Lipase/Acylhydrolase; High confidence in function and specificity; esterase 1882941 4798534 llmg_1905 Lactococcus lactis subsp. cremoris MG1363 esterase YP_001033171.1 1882378 R 416870 CDS YP_001033172.1 125624689 4798416 complement(1883038..1885656) 1 NC_009004.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 1885656 alaS 4798416 alaS Lactococcus lactis subsp. cremoris MG1363 alanyl-tRNA synthetase YP_001033172.1 1883038 R 416870 CDS YP_001033173.1 125624690 4796714 complement(1885919..1886845) 1 NC_009004.1 High confidence in function and specificity; foldase prsA 1886845 pmpA 4796714 pmpA Lactococcus lactis subsp. cremoris MG1363 foldase prsA YP_001033173.1 1885919 R 416870 CDS YP_001033174.1 125624691 4797972 complement(1886991..1887683) 1 NC_009004.1 O-methyltransferase, family 3; High confidence in function and specificity; methyltransferase 1887683 4797972 llmg_1908 Lactococcus lactis subsp. cremoris MG1363 methyltransferase YP_001033174.1 1886991 R 416870 CDS YP_001033175.1 125624692 4797941 complement(1887686..1889491) 1 NC_009004.1 Peptidase M3B, oligoendopeptidase F; High confidence in function and specificity; PepF protein 1889491 pepF 4797941 pepF Lactococcus lactis subsp. cremoris MG1363 PepF protein YP_001033175.1 1887686 R 416870 CDS YP_001033176.1 125624693 4798771 complement(1890624..1891709) 1 NC_009004.1 Protein of unknown function DUF218; hypothetical protein 1891709 4798771 llmg_1911 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033176.1 1890624 R 416870 CDS YP_001033177.1 125624694 4797942 complement(1891862..1892710) 1 NC_009004.1 COG:4814 Uncharacterized protein with an alpha/beta hydrolase fold, Bacterial protein of unknown function DUF915; hypothetical protein 1892710 4797942 llmg_1912 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033177.1 1891862 R 416870 CDS YP_001033178.1 125624695 4797963 complement(1892919..1894340) 1 NC_009004.1 Xanthine/uracil/vitamin C permease; Conserved hypothetical protein; xanthine/uracil/vitamin C permease 1894340 pbuO 4797963 pbuO Lactococcus lactis subsp. cremoris MG1363 xanthine/uracil/vitamin C permease YP_001033178.1 1892919 R 416870 CDS YP_001033179.1 125624696 4798147 1894647..1895483 1 NC_009004.1 Cof-subfamily: Cof-like hydrolase TIGRFAM00099; Conserved hypothetical protein; hypothetical protein 1895483 4798147 llmg_1914 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033179.1 1894647 D 416870 CDS YP_001033180.1 125624697 4798446 1895665..1896435 1 NC_009004.1 Fe-S oxidoreductase 1896435 4798446 llmg_1915 Lactococcus lactis subsp. cremoris MG1363 Fe-S oxidoreductase YP_001033180.1 1895665 D 416870 CDS YP_001033181.1 125624698 4797362 1896445..1897917 1 NC_009004.1 Similar to electron transport protein ykgF (E. coli), TIGR00273: iron-sulfur cluster binding protein; Conserved hypothetical protein; electron transport protein 1897917 4797362 llmg_1916 Lactococcus lactis subsp. cremoris MG1363 electron transport protein YP_001033181.1 1896445 D 416870 CDS YP_001033182.1 125624699 4797370 1897920..1898603 1 NC_009004.1 Protein of unknown function DUF162, Uncharacterized ACR, YkgG family COG1556; Conserved hypothetical protein; hypothetical protein 1898603 4797370 llmg_1917 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033182.1 1897920 D 416870 CDS YP_001033183.1 125624700 4797160 complement(1898680..1899393) 1 NC_009004.1 Protein of unknown function UPF0005; Conserved hypothetical protein; hypothetical protein 1899393 4797160 llmg_1918 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033183.1 1898680 R 416870 CDS YP_001033184.1 125624701 4798286 complement(1899507..1900421) 1 NC_009004.1 Conserved hypothetical protein, similarity to eucaryotic, Diacylglycerol kinase (catalytic domain); hypothetical protein 1900421 4798286 llmg_1919 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033184.1 1899507 R 416870 CDS YP_001033185.1 125624702 4797855 complement(1900601..1901113) 1 NC_009004.1 Metal-dependent phosphohydrolase, HD region; hypothetical protein 1901113 4797855 llmg_1920 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033185.1 1900601 R 416870 CDS YP_001033186.1 125624703 4797837 1901443..1901676 1 NC_009004.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 1901676 rpsT 4797837 rpsT Lactococcus lactis subsp. cremoris MG1363 30S ribosomal protein S20 YP_001033186.1 1901443 D 416870 CDS YP_001033187.1 125624704 4797368 complement(1901770..1904271) 1 NC_009004.1 RecD/TraA family; High confidence in function and specificity; exodeoxyribonuclease V subunit alpha 1904271 recD 4797368 recD Lactococcus lactis subsp. cremoris MG1363 exodeoxyribonuclease V subunit alpha YP_001033187.1 1901770 R 416870 CDS YP_001033188.1 125624705 4796607 complement(1904268..1904861) 1 NC_009004.1 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; High confidence in function and specificity; phosphoglycerate mutase 1904861 gpmC 4796607 gpmC Lactococcus lactis subsp. cremoris MG1363 phosphoglycerate mutase YP_001033188.1 1904268 R 416870 CDS YP_001033189.1 125624706 4798602 complement(1904864..1905703) 1 NC_009004.1 catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; prephenate dehydratase 1905703 pheA 4798602 pheA Lactococcus lactis subsp. cremoris MG1363 prephenate dehydratase YP_001033189.1 1904864 R 416870 CDS YP_001033190.1 125624707 4798412 complement(1905705..1906193) 1 NC_009004.1 AroK protein 1906193 aroK 4798412 aroK Lactococcus lactis subsp. cremoris MG1363 AroK protein YP_001033190.1 1905705 R 416870 CDS YP_001033191.1 125624708 4798266 complement(1906217..1907509) 1 NC_009004.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1907509 aroA 4798266 aroA Lactococcus lactis subsp. cremoris MG1363 3-phosphoshikimate 1-carboxyvinyltransferase YP_001033191.1 1906217 R 416870 CDS YP_001033192.1 125624709 4799070 complement(1907629..1908693) 1 NC_009004.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate; prephenate dehydrogenase 1908693 tyrA 4799070 tyrA Lactococcus lactis subsp. cremoris MG1363 prephenate dehydrogenase YP_001033192.1 1907629 R 416870 CDS YP_001033193.1 125624710 4798278 complement(1908697..1909572) 1 NC_009004.1 Histidine kinase; High confidence in function and specificity; sensor histidine kinase 1909572 kinG 4798278 kinG Lactococcus lactis subsp. cremoris MG1363 sensor histidine kinase YP_001033193.1 1908697 R 416870 CDS YP_001033194.1 125624711 4797728 complement(1909559..1910230) 1 NC_009004.1 Response regulator; Conserved hypothetical protein; response regulator 1910230 llrG 4797728 llrG Lactococcus lactis subsp. cremoris MG1363 response regulator YP_001033194.1 1909559 R 416870 CDS YP_001033195.1 125624712 4796701 complement(1910233..1911297) 1 NC_009004.1 VanZ like family; hypothetical protein 1911297 4796701 llmg_1930 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033195.1 1910233 R 416870 CDS YP_001033196.1 125624713 4798255 complement(1913487..1914266) 1 NC_009004.1 Sulfate/thiosulfate import ATP-binding protein cysA. ABC transporter related; High confidence in function and specificity; Sulfate/thiosulfate import ATP-binding protein cysA 1914266 4798255 llmg_1932 Lactococcus lactis subsp. cremoris MG1363 Sulfate/thiosulfate import ATP-binding protein cysA YP_001033196.1 1913487 R 416870 CDS YP_001033197.1 125624714 4797441 complement(1914460..1914816) 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 1914816 4797441 llmg_1933 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033197.1 1914460 R 416870 CDS YP_001033198.1 125624715 4798316 complement(1914939..1916105) 1 NC_009004.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 1916105 aroC 4798316 aroC Lactococcus lactis subsp. cremoris MG1363 chorismate synthase YP_001033198.1 1914939 R 416870 CDS YP_001033199.1 125624716 4798766 complement(1916738..1917337) 1 NC_009004.1 Protein of unknown function DUF1054; hypothetical protein 1917337 4798766 llmg_1936 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033199.1 1916738 R 416870 CDS YP_001033200.1 125624717 4797815 complement(1917709..1918632) 1 NC_009004.1 Protein of unknown function DUF606; hypothetical protein 1918632 4797815 llmg_1937 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033200.1 1917709 R 416870 CDS YP_001033201.1 125624718 4797811 complement(1918746..1919816) 1 NC_009004.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 1919816 aroB 4797811 aroB Lactococcus lactis subsp. cremoris MG1363 3-dehydroquinate synthase YP_001033201.1 1918746 R 416870 CDS YP_001033202.1 125624719 4798936 complement(1919813..1920673) 1 NC_009004.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 1920673 aroE 4798936 aroE Lactococcus lactis subsp. cremoris MG1363 shikimate 5-dehydrogenase YP_001033202.1 1919813 R 416870 CDS YP_001033203.1 125624720 4798102 complement(1920851..1921510) 1 NC_009004.1 DedA family; hypothetical protein 1921510 4798102 llmg_1941 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033203.1 1920851 R 416870 CDS YP_001033204.1 125624721 4797831 1921895..1924039 1 NC_009004.1 glutamine ABC transporter permease and substrate binding protein; High confidence in function and specificity; glutamine ABC transporter permease and substrate binding protein 1924039 glnP 4797831 glnP Lactococcus lactis subsp. cremoris MG1363 glutamine ABC transporter permease and substrate binding protein YP_001033204.1 1921895 D 416870 CDS YP_001033205.1 125624722 4797844 1924062..1924805 1 NC_009004.1 High confidence in function and specificity; glutamine ABC transporter ATP-binding protein 1924805 glnQ 4797844 glnQ Lactococcus lactis subsp. cremoris MG1363 glutamine ABC transporter ATP-binding protein YP_001033205.1 1924062 D 416870 CDS YP_001033206.1 125624723 4798031 complement(1924864..1926804) 1 NC_009004.1 hypothetical protein 1926804 4798031 llmg_1944 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033206.1 1924864 R 416870 CDS YP_001033207.1 125624724 4798465 complement(1926908..1927333) 1 NC_009004.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon 1927333 atpC 4798465 atpC Lactococcus lactis subsp. cremoris MG1363 ATP synthase F0F1 subunit epsilon YP_001033207.1 1926908 R 416870 CDS YP_001033208.1 125624725 4797781 complement(1927518..1928978) 1 NC_009004.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta 1928978 atpD 4797781 atpD Lactococcus lactis subsp. cremoris MG1363 ATP synthase F0F1 subunit beta YP_001033208.1 1927518 R 416870 CDS YP_001033209.1 125624726 4797793 complement(1929099..1929968) 1 NC_009004.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma 1929968 atpG 4797793 atpG Lactococcus lactis subsp. cremoris MG1363 ATP synthase F0F1 subunit gamma YP_001033209.1 1929099 R 416870 CDS YP_001033210.1 125624727 4798114 complement(1929984..1931486) 1 NC_009004.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha 1931486 atpA 4798114 atpA Lactococcus lactis subsp. cremoris MG1363 ATP synthase F0F1 subunit alpha YP_001033210.1 1929984 R 416870 CDS YP_001033211.1 125624728 4798488 complement(1931675..1932202) 1 NC_009004.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta 1932202 atpH 4798488 atpH Lactococcus lactis subsp. cremoris MG1363 ATP synthase F0F1 subunit delta YP_001033211.1 1931675 R 416870 CDS YP_001033212.1 125624729 4798625 complement(1932204..1932710) 1 NC_009004.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B 1932710 atpF 4798625 atpF Lactococcus lactis subsp. cremoris MG1363 ATP synthase F0F1 subunit B YP_001033212.1 1932204 R 416870 CDS YP_001033213.1 125624730 4797802 complement(1932725..1933438) 1 NC_009004.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A 1933438 atpB 4797802 atpB Lactococcus lactis subsp. cremoris MG1363 ATP synthase F0F1 subunit A YP_001033213.1 1932725 R 416870 CDS YP_001033214.1 125624731 4797764 complement(1933485..1933700) 1 NC_009004.1 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C 1933700 atpE 4797764 atpE Lactococcus lactis subsp. cremoris MG1363 ATP synthase F0F1 subunit C YP_001033214.1 1933485 R 416870 CDS YP_001033215.1 125624732 4797796 complement(1933883..1934659) 1 NC_009004.1 esterase; High confidence in function and specificity; tributyrin esterase 1934659 estA 4797796 estA Lactococcus lactis subsp. cremoris MG1363 tributyrin esterase YP_001033215.1 1933883 R 416870 CDS YP_001033216.1 125624733 4798781 complement(1937133..1937747) 1 NC_009004.1 Competence protein ComEA helix-hairpin-helix region; High confidence in function and specificity; competence protein 1937747 comEA 4798781 comEA Lactococcus lactis subsp. cremoris MG1363 competence protein YP_001033216.1 1937133 R 416870 CDS YP_001033217.1 125624734 4798777 complement(1937847..1939208) 1 NC_009004.1 ABC transporter permease; Conserved hypothetical protein; hypothetical protein 1939208 4798777 llmg_1956 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033217.1 1937847 R 416870 CDS YP_001033218.1 125624735 4797788 complement(1939205..1940137) 1 NC_009004.1 ABC transporter ATP binding protein; High confidence in function and specificity; ABC transporter ATP-binding protein 1940137 4797788 llmg_1957 Lactococcus lactis subsp. cremoris MG1363 ABC transporter ATP-binding protein YP_001033218.1 1939205 R 416870 CDS YP_001033219.1 125624736 4798627 complement(1940243..1940428) 1 NC_009004.1 hypothetical protein 1940428 4798627 llmg_1958 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033219.1 1940243 R 416870 CDS YP_001033220.1 125624737 4797833 complement(1940757..1941317) 1 NC_009004.1 Phosphinothricin N-acetyltransferase (GNAT) family; High confidence in function and specificity; phosphinothricin N-acetyltransferase 1941317 bar 4797833 bar Lactococcus lactis subsp. cremoris MG1363 phosphinothricin N-acetyltransferase YP_001033220.1 1940757 R 416870 CDS YP_001033221.1 125624738 4798640 complement(1941491..1942669) 1 NC_009004.1 cation transporter; Conserved hypothetical protein; hypothetical protein 1942669 4798640 llmg_1960 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033221.1 1941491 R 416870 CDS YP_001033222.1 125624739 4798435 complement(1943058..1943714) 1 NC_009004.1 TENA/THI-4 protein; High confidence in function and specificity; transcriptional activator TenA 1943714 tenA 4798435 tenA Lactococcus lactis subsp. cremoris MG1363 transcriptional activator TenA YP_001033222.1 1943058 R 416870 CDS YP_001033223.1 125624740 4797536 complement(1943932..1944261) 1 NC_009004.1 CHY zinc finger; Conserved hypothetical protein; hypothetical protein 1944261 4797536 llmg_1962 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033223.1 1943932 R 416870 CDS YP_001033224.1 125624741 4797525 complement(1944255..1945226) 1 NC_009004.1 Biotin-- [acetyl-CoA-carboxylase] synthetase; High confidence in function and specificity; biotin--[acetyl-CoA-carboxylase] ligase and biotin operon repressor 1945226 birA1 4797525 birA1 Lactococcus lactis subsp. cremoris MG1363 biotin--[acetyl-CoA-carboxylase] ligase and biotin operon repressor YP_001033224.1 1944255 R 416870 CDS YP_001033225.1 125624742 4798221 complement(1945232..1945801) 1 NC_009004.1 BioY protein; Conserved hypothetical protein; hypothetical protein 1945801 bioY 4798221 bioY Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033225.1 1945232 R 416870 CDS YP_001033226.1 125624743 4798301 1945938..1947182 1 NC_009004.1 Acetyl-coenzyme A synthetase; High confidence in function and specificity; AMP-binding protein 1947182 4798301 llmg_1965 Lactococcus lactis subsp. cremoris MG1363 AMP-binding protein YP_001033226.1 1945938 D 416870 CDS YP_001033227.1 125624744 4798019 complement(1948940..1949203) 1 NC_009004.1 hypothetical protein 1949203 4798019 llmg_1966 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033227.1 1948940 R 416870 CDS YP_001033228.1 125624745 4797806 complement(1949203..1949673) 1 NC_009004.1 hypothetical protein 1949673 4797806 llmg_1967 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033228.1 1949203 R 416870 CDS YP_001033229.1 125624746 4798700 complement(1949781..1950071) 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 1950071 4798700 llmg_1968 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033229.1 1949781 R 416870 CDS YP_001033230.1 125624747 4798702 complement(1950420..1951832) 1 NC_009004.1 FeS assembly protein SufB; hypothetical protein 1951832 sufB 4798702 sufB Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033230.1 1950420 R 416870 CDS YP_001033231.1 125624748 4798596 complement(1951928..1952386) 1 NC_009004.1 May be involved in the formation or repair of [Fe- S] clusters present in iron-sulfur proteins; hypothetical protein 1952386 nifU 4798596 nifU Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033231.1 1951928 R 416870 CDS YP_001033232.1 125624749 4797952 complement(1952520..1953002) 1 NC_009004.1 hypothetical protein 1953002 4797952 llmg_1971 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033232.1 1952520 R 416870 CDS YP_001033233.1 125624750 4798707 complement(1953004..1954221) 1 NC_009004.1 cysteine desulfurases, SufS subfamily; High confidence in function and specificity; hypothetical protein 1954221 4798707 llmg_1972 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033233.1 1953004 R 416870 CDS YP_001033234.1 125624751 4798576 complement(1954221..1955477) 1 NC_009004.1 FeS assembly protein SufD; hypothetical protein 1955477 4798576 llmg_1973 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033234.1 1954221 R 416870 CDS YP_001033235.1 125624752 4798719 complement(1955617..1956387) 1 NC_009004.1 ATP-dependent transporter; Conserved hypothetical protein; ATP-dependent transporter 1956387 4798719 llmg_1974 Lactococcus lactis subsp. cremoris MG1363 ATP-dependent transporter YP_001033235.1 1955617 R 416870 CDS YP_001033236.1 125624753 4798698 1956608..1957177 1 NC_009004.1 hypothetical protein 1957177 4798698 llmg_1975 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033236.1 1956608 D 416870 CDS YP_001033237.1 125624754 4798528 complement(1958065..1959390) 1 NC_009004.1 Phospho-N-acetylmuramoyl-pentapeptide-transferase. Glycosyl transferase; High confidence in function and specificity; polysaccharide biosynthesis protein 1959390 4798528 llmg_1976 Lactococcus lactis subsp. cremoris MG1363 polysaccharide biosynthesis protein YP_001033237.1 1958065 R 416870 CDS YP_001033238.1 125624755 4798567 complement(1959393..1960094) 1 NC_009004.1 Similar to B. subtilis MecA,(Negative regulator of genetic competence in B. subtilis); High confidence in function and specificity; MecA-like protein 1960094 4798567 llmg_1977 Lactococcus lactis subsp. cremoris MG1363 MecA-like protein YP_001033238.1 1959393 R 416870 CDS YP_001033239.1 125624756 4798575 complement(1960224..1960958) 1 NC_009004.1 Glutamate ABC transporter ATP binding protein; Conserved hypothetical protein; glutamate ABC transporter ATP-binding protein 1960958 gltQ 4798575 gltQ Lactococcus lactis subsp. cremoris MG1363 glutamate ABC transporter ATP-binding protein YP_001033239.1 1960224 R 416870 CDS YP_001033240.1 125624757 4798813 complement(1960958..1961644) 1 NC_009004.1 amino acid ABC transporter permease; High confidence in function and specificity; glutamate ABC transporter permease 1961644 gltP 4798813 gltP Lactococcus lactis subsp. cremoris MG1363 glutamate ABC transporter permease YP_001033240.1 1960958 R 416870 CDS YP_001033241.1 125624758 4796841 complement(1961791..1962699) 1 NC_009004.1 Diacylglycerol kinase catalytic domain; hypothetical protein 1962699 4796841 llmg_1980 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033241.1 1961791 R 416870 CDS YP_001033242.1 125624759 4798573 complement(1962823..1966446) 1 NC_009004.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 1966446 rpoC 4798573 rpoC Lactococcus lactis subsp. cremoris MG1363 DNA-directed RNA polymerase subunit beta' YP_001033242.1 1962823 R 416870 CDS YP_001033243.1 125624760 4798827 complement(1966555..1970145) 1 NC_009004.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 1970145 rpoB 4798827 rpoB Lactococcus lactis subsp. cremoris MG1363 DNA-directed RNA polymerase subunit beta YP_001033243.1 1966555 R 416870 CDS YP_001033244.1 125624761 4798826 complement(1970414..1971013) 1 NC_009004.1 transcriptional repressor, CodY family; High confidence in function and specificity; CodY family transcriptional regulator 1971013 codZ 4798826 codZ Lactococcus lactis subsp. cremoris MG1363 CodY family transcriptional regulator YP_001033244.1 1970414 R 416870 CDS YP_001033245.1 125624762 4798768 1971249..1971923 1 NC_009004.1 Family membership; transcriptional regulator 1971923 4798768 llmg_1984 Lactococcus lactis subsp. cremoris MG1363 transcriptional regulator YP_001033245.1 1971249 D 416870 CDS YP_001033246.1 125624763 4798570 1972038..1973921 1 NC_009004.1 Peptidase M13; High confidence in function and specificity; neutral endopeptidase O2 1973921 pepO2 4798570 pepO2 Lactococcus lactis subsp. cremoris MG1363 neutral endopeptidase O2 YP_001033246.1 1972038 D 416870 CDS YP_001033247.1 125624764 4798131 complement(1973970..1974275) 1 NC_009004.1 methylated-DNA--protein-cysteine methyltransferase; High confidence in function and specificity; hypothetical protein 1974275 4798131 llmg_1986 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033247.1 1973970 R 416870 CDS YP_001033248.1 125624765 4798578 complement(1974345..1976018) 1 NC_009004.1 Polysaccharide biosynthesis protein; hypothetical protein 1976018 4798578 llmg_1988 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033248.1 1974345 R 416870 CDS YP_001033249.1 125624766 4798713 1976229..1977680 1 NC_009004.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 1977680 murE 4798713 murE Lactococcus lactis subsp. cremoris MG1363 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_001033249.1 1976229 D 416870 CDS YP_001033250.1 125624767 4796913 complement(1977762..1978022) 1 NC_009004.1 SSF47413: Lambda repressor-like, DNA-binding; hypothetical protein 1978022 4796913 llmg_1990 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033250.1 1977762 R 416870 CDS YP_001033251.1 125624768 4798721 complement(1978043..1979065) 1 NC_009004.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase 1979065 adhA 4798721 adhA Lactococcus lactis subsp. cremoris MG1363 alcohol dehydrogenase YP_001033251.1 1978043 R 416870 CDS YP_001033252.1 125624769 4797653 1979285..1981063 1 NC_009004.1 ATP-requiring DNA helicase RecQ; High confidence in function and specificity; ATP-dependent DNA helicase RecQ 1981063 recQ 4797653 recQ Lactococcus lactis subsp. cremoris MG1363 ATP-dependent DNA helicase RecQ YP_001033252.1 1979285 D 416870 CDS YP_001033253.1 125624770 4797055 complement(1981100..1982623) 1 NC_009004.1 Amino acid permease-associated region; High confidence in function and specificity; transporter 1982623 4797055 llmg_1993 Lactococcus lactis subsp. cremoris MG1363 transporter YP_001033253.1 1981100 R 416870 CDS YP_001033254.1 125624771 4798720 complement(1982905..1984146) 1 NC_009004.1 catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 1984146 pepT 4798720 pepT Lactococcus lactis subsp. cremoris MG1363 peptidase T YP_001033254.1 1982905 R 416870 CDS YP_001033255.1 125624772 4798132 complement(1984175..1984972) 1 NC_009004.1 hypothetical protein 1984972 4798132 llmg_1995 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033255.1 1984175 R 416870 CDS YP_001033256.1 125624773 4798571 complement(1984972..1985916) 1 NC_009004.1 catalyzes the hydrolysis of pyrophosphate to phosphate; manganese-dependent inorganic pyrophosphatase 1985916 ppa 4798571 ppa Lactococcus lactis subsp. cremoris MG1363 manganese-dependent inorganic pyrophosphatase YP_001033256.1 1984972 R 416870 CDS YP_001033257.1 125624774 4797023 complement(1986117..1986908) 1 NC_009004.1 Pyruvate formate-lyase 1 activating enzyme; High confidence in function and specificity; pyruvate-formate lyase activating enzyme 1986908 pflA 4797023 pflA Lactococcus lactis subsp. cremoris MG1363 pyruvate-formate lyase activating enzyme YP_001033257.1 1986117 R 416870 CDS YP_001033258.1 125624775 4797309 complement(1987127..1988464) 1 NC_009004.1 Protein of unknown function DUF21; hypothetical protein 1988464 4797309 llmg_1999 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033258.1 1987127 R 416870 CDS YP_001033259.1 125624776 4798715 complement(1988584..1989699) 1 NC_009004.1 Protein of unknown function DUF20; Conserved hypothetical protein; permease 1989699 4798715 llmg_2000 Lactococcus lactis subsp. cremoris MG1363 permease YP_001033259.1 1988584 R 416870 CDS YP_001033260.1 125624777 4798579 complement(1990003..1990467) 1 NC_009004.1 Protein of unknown function; hypothetical protein 1990467 4798579 llmg_2002 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033260.1 1990003 R 416870 CDS YP_001033261.1 125624778 4798709 complement(1990464..1991033) 1 NC_009004.1 High confidence in function and specificity; UDP-glucose 4-epimerase 1991033 4798709 llmg_2003 Lactococcus lactis subsp. cremoris MG1363 UDP-glucose 4-epimerase YP_001033261.1 1990464 R 416870 CDS YP_001033262.1 125624779 4798723 1991280..1991732 1 NC_009004.1 probable acetyltransferase (GNAT) family; hypothetical protein 1991732 4798723 llmg_2004 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033262.1 1991280 D 416870 CDS YP_001033263.1 125624780 4798718 complement(1991789..1992226) 1 NC_009004.1 cell wall hydrolase 1992226 4798718 llmg_2005 Lactococcus lactis subsp. cremoris MG1363 cell wall hydrolase YP_001033263.1 1991789 R 416870 CDS YP_001033264.1 125624781 4798703 1992275..1992862 1 NC_009004.1 zimilar to prophage pi3 protein 58; hypothetical protein 1992862 4798703 llmg_2006 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033264.1 1992275 D 416870 CDS YP_001033265.1 125624782 4798722 complement(1992989..1993570) 1 NC_009004.1 Uracil-DNA glycosylase superfamily; Conserved hypothetical protein; hypothetical protein 1993570 4798722 llmg_2007 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033265.1 1992989 R 416870 CDS YP_001033266.1 125624783 4796829 complement(1993652..1996483) 1 NC_009004.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 1996483 uvrA 4796829 uvrA Lactococcus lactis subsp. cremoris MG1363 excinuclease ABC subunit A YP_001033266.1 1993652 R 416870 CDS YP_001033267.1 125624784 4797344 complement(1996628..1997266) 1 NC_009004.1 hypothetical protein 1997266 4797344 llmg_2009 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033267.1 1996628 R 416870 CDS YP_001033268.1 125624785 4797493 1997373..1997669 1 NC_009004.1 hypothetical protein 1997669 4797493 llmg_2010 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033268.1 1997373 D 416870 CDS YP_001033269.1 125624786 4797475 complement(1997679..1999052) 1 NC_009004.1 Family membership; amino acid permease 1999052 4797475 llmg_2011 Lactococcus lactis subsp. cremoris MG1363 amino acid permease YP_001033269.1 1997679 R 416870 CDS YP_001033270.1 125624787 4798287 complement(1999452..2000369) 1 NC_009004.1 Oxidoreductase, Oxidoreductase, NAD- binding Rossmann fold; hypothetical protein 2000369 4798287 llmg_2012 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033270.1 1999452 R 416870 CDS YP_001033271.1 125624788 4799053 complement(2000399..2001034) 1 NC_009004.1 PF04263.5: Thiamin pyrophosphokinase, catalytic region, PF04265: Thiamin pyrophosphokinase, vitamin B1 binding domain; High confidence in function and specificity; thiamin pyrophosphokinase 2001034 thiN 4799053 thiN Lactococcus lactis subsp. cremoris MG1363 thiamin pyrophosphokinase YP_001033271.1 2000399 R 416870 CDS YP_001033272.1 125624789 4796890 complement(2001031..2001378) 1 NC_009004.1 pyrophosphohydrolase, MazG-related, GP37 type; hypothetical protein 2001378 4796890 llmg_2014 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033272.1 2001031 R 416870 CDS YP_001033273.1 125624790 4799033 complement(2001410..2001859) 1 NC_009004.1 hypothetical protein 2001859 4799033 llmg_2015 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033273.1 2001410 R 416870 CDS YP_001033274.1 125624791 4798079 2002053..2002571 1 NC_009004.1 hypothetical protein 2002571 4798079 llmg_2016 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033274.1 2002053 D 416870 CDS YP_001033275.1 125624792 4796865 complement(2002619..2003962) 1 NC_009004.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 2003962 asnC 4796865 asnC Lactococcus lactis subsp. cremoris MG1363 asparaginyl-tRNA synthetase YP_001033275.1 2002619 R 416870 CDS YP_001033276.1 125624793 4797206 complement(2004010..2004321) 1 NC_009004.1 hypothetical protein 2004321 4797206 llmg_2018 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033276.1 2004010 R 416870 CDS YP_001033277.1 125624794 4796808 complement(2004314..2005495) 1 NC_009004.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 2005495 aspB 4796808 aspB Lactococcus lactis subsp. cremoris MG1363 aspartate aminotransferase YP_001033277.1 2004314 R 416870 CDS YP_001033278.1 125624795 4797205 complement(2005492..2005935) 1 NC_009004.1 hypothetical protein 2005935 4797205 llmg_2020 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033278.1 2005492 R 416870 CDS YP_001033279.1 125624796 4798775 complement(2006071..2008446) 1 NC_009004.1 DnaQ exonuclease/DinG family helicase; High confidence in function and specificity; ATP-dependent helicase dinG-like protein 2008446 dinG 4798775 dinG Lactococcus lactis subsp. cremoris MG1363 ATP-dependent helicase dinG-like protein YP_001033279.1 2006071 R 416870 CDS YP_001033280.1 125624797 4798911 2008550..2008672 1 NC_009004.1 hypothetical protein 2008672 4798911 llmg_2022 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033280.1 2008550 D 416870 CDS YP_001033281.1 125624798 4798067 2008694..2009131 1 NC_009004.1 UspA Universal stress protein family; High confidence in function and specificity; universal stress protein A 2009131 4798067 llmg_2023 Lactococcus lactis subsp. cremoris MG1363 universal stress protein A YP_001033281.1 2008694 D 416870 CDS YP_001033282.1 125624799 4798123 complement(2009303..2011105) 1 NC_009004.1 Bacterial extracellular solute-binding protein; High confidence in function and specificity; oligopeptide-binding protein oppA2 precursor 2011105 oppA2 4798123 oppA2 Lactococcus lactis subsp. cremoris MG1363 oligopeptide-binding protein oppA2 precursor YP_001033282.1 2009303 R 416870 CDS YP_001033283.1 125624800 4799092 complement(2011218..2012102) 1 NC_009004.1 Binding-protein-dependent transport systems inner membrane component; High confidence in function and specificity; oligopeptide transport system permease oppC2 2012102 oppC2 4799092 oppC2 Lactococcus lactis subsp. cremoris MG1363 oligopeptide transport system permease oppC2 YP_001033283.1 2011218 R 416870 CDS YP_001033284.1 125624801 4799088 complement(2012112..2013071) 1 NC_009004.1 Binding-protein-dependent transport systems inner membrane component; High confidence in function and specificity; peptide transport system permease oppB2 2013071 oppB2 4799088 oppB2 Lactococcus lactis subsp. cremoris MG1363 peptide transport system permease oppB2 YP_001033284.1 2012112 R 416870 CDS YP_001033285.1 125624802 4799086 complement(2015238..2015597) 1 NC_009004.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 2015597 rplT 4799086 rplT Lactococcus lactis subsp. cremoris MG1363 50S ribosomal protein L20 YP_001033285.1 2015238 R 416870 CDS YP_001033286.1 125624803 4797849 complement(2015861..2016061) 1 NC_009004.1 Ribosomal protein L35; Conserved hypothetical protein; 50S ribosomal protein L35 2016061 rpmI 4797849 rpmI Lactococcus lactis subsp. cremoris MG1363 50S ribosomal protein L35 YP_001033286.1 2015861 R 416870 CDS YP_001033287.1 125624804 4798807 complement(2016189..2016839) 1 NC_009004.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 2016839 infC 4798807 infC Lactococcus lactis subsp. cremoris MG1363 translation initiation factor IF-3 YP_001033287.1 2016189 R 416870 CDS YP_001033288.1 125624805 4796686 2017144..2017272 1 NC_009004.1 hypothetical protein 2017272 4796686 llmg_2032 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033288.1 2017144 D 416870 CDS YP_001033289.1 125624806 4798093 2017303..2017851 1 NC_009004.1 hypothetical protein 2017851 4798093 llmg_2033 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033289.1 2017303 D 416870 CDS YP_001033290.1 125624807 4798099 complement(2017879..2018565) 1 NC_009004.1 Haloacid dehalogenase-like hydrolase, HAD superfamily; HAD superfamily hydrolase 2018565 4798099 llmg_2034 Lactococcus lactis subsp. cremoris MG1363 HAD superfamily hydrolase YP_001033290.1 2017879 R 416870 CDS YP_001033291.1 125624808 4798083 complement(2018737..2020614) 1 NC_009004.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 2020614 gidA 4798083 gidA Lactococcus lactis subsp. cremoris MG1363 tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_001033291.1 2018737 R 416870 CDS YP_001033292.1 125624809 4799132 complement(2020999..2021562) 1 NC_009004.1 hypothetical protein 2021562 4799132 llmg_2036 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033292.1 2020999 R 416870 CDS YP_001033293.1 125624810 4796769 complement(2021695..2022063) 1 NC_009004.1 Protein of unknown function DUF1033; hypothetical protein 2022063 4796769 llmg_2037 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033293.1 2021695 R 416870 CDS YP_001033294.1 125624811 4798096 complement(2022177..2022596) 1 NC_009004.1 Uncharacterised conserved protein; Conserved hypothetical protein; ribonuclease III 2022596 4798096 llmg_2039 Lactococcus lactis subsp. cremoris MG1363 ribonuclease III YP_001033294.1 2022177 R 416870 CDS YP_001033295.1 125624812 4798035 complement(2022571..2023917) 1 NC_009004.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 2023917 cysS 4798035 cysS Lactococcus lactis subsp. cremoris MG1363 cysteinyl-tRNA synthetase YP_001033295.1 2022571 R 416870 CDS YP_001033296.1 125624813 4798867 complement(2023930..2024523) 1 NC_009004.1 Protein of unknown function DUF1211; hypothetical protein 2024523 4798867 llmg_2041 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033296.1 2023930 R 416870 CDS YP_001033297.1 125624814 4797797 complement(2024537..2025136) 1 NC_009004.1 serine O-acetyltransferase; High confidence in function and specificity; serine acetyltransferase 2025136 cysE 4797797 cysE Lactococcus lactis subsp. cremoris MG1363 serine acetyltransferase YP_001033297.1 2024537 R 416870 CDS YP_001033298.1 125624815 4798864 complement(2025242..2026012) 1 NC_009004.1 hypothetical protein 2026012 4798864 llmg_2043 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033298.1 2025242 R 416870 CDS YP_001033299.1 125624816 4799121 complement(2026280..2028580) 1 NC_009004.1 Polyribonucleotide nucleotidyltransferase; High confidence in function and specificity; polynucleotide phosphorylase 2028580 pnpA 4799121 pnpA Lactococcus lactis subsp. cremoris MG1363 polynucleotide phosphorylase YP_001033299.1 2026280 R 416870 CDS YP_001033300.1 125624817 4799065 complement(2028861..2030006) 1 NC_009004.1 phosphoribosylpyrophosphate synthetase; hypothetical protein 2030006 prsA 4799065 prsA Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033300.1 2028861 R 416870 CDS YP_001033301.1 125624818 4796992 2030371..2031336 1 NC_009004.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 2031336 prsB 4796992 prsB Lactococcus lactis subsp. cremoris MG1363 ribose-phosphate pyrophosphokinase YP_001033301.1 2030371 D 416870 CDS YP_001033302.1 125624819 4798546 complement(2031441..2031872) 1 NC_009004.1 UspA Universal stress protein family; Conserved hypothetical protein; universal stress protein E 2031872 4798546 llmg_2047 Lactococcus lactis subsp. cremoris MG1363 universal stress protein E YP_001033302.1 2031441 R 416870 CDS YP_001033303.1 125624820 4796820 2032415..2033296 1 NC_009004.1 Cysteine desulfurase/Cysteine sulfinate desulfinase; High confidence in function and specificity; iron-sulfur cofactor synthesis protein 2033296 nifS 4796820 nifS Lactococcus lactis subsp. cremoris MG1363 iron-sulfur cofactor synthesis protein YP_001033303.1 2032415 D 416870 CDS YP_001033304.1 125624821 4797248 2033322..2033666 1 NC_009004.1 hypothetical protein 2033666 4797248 llmg_2049 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033304.1 2033322 D 416870 CDS YP_001033305.1 125624822 4798092 complement(2033755..2034942) 1 NC_009004.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 2034942 tufA 4798092 tufA Lactococcus lactis subsp. cremoris MG1363 elongation factor Tu YP_001033305.1 2033755 R 416870 CDS YP_001033306.1 125624823 4798244 2035186..2035368 1 NC_009004.1 hypothetical protein 2035368 4798244 llmg_2051 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033306.1 2035186 D 416870 CDS YP_001033307.1 125624824 4798084 2035427..2035543 1 NC_009004.1 hypothetical protein 2035543 4798084 llmg_2052 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033307.1 2035427 D 416870 CDS YP_001033308.1 125624825 4797961 complement(2035603..2038401) 1 NC_009004.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 2038401 ileS 4797961 ileS Lactococcus lactis subsp. cremoris MG1363 isoleucyl-tRNA synthetase YP_001033308.1 2035603 R 416870 CDS YP_001033309.1 125624826 4797630 2038605..2038745 1 NC_009004.1 hypothetical protein 2038745 4797630 llmg_2054 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033309.1 2038605 D 416870 CDS YP_001033310.1 125624827 4798451 complement(2038848..2039783) 1 NC_009004.1 cell division initiation protein, DivIVA; hypothetical protein 2039783 4798451 llmg_2055 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033310.1 2038848 R 416870 CDS YP_001033311.1 125624828 4797367 complement(2039840..2040559) 1 NC_009004.1 hypothetical protein 2040559 4797367 llmg_2056 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033311.1 2039840 R 416870 CDS YP_001033312.1 125624829 4797372 complement(2040628..2040903) 1 NC_009004.1 Protein of unknown function,YGGT protein family, predicted integral membrane protein; hypothetical protein 2040903 4797372 llmg_2057 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033312.1 2040628 R 416870 CDS YP_001033313.1 125624830 4796848 complement(2040903..2041493) 1 NC_009004.1 Protein of unknown function DUF552; Conserved hypothetical protein; hypothetical protein 2041493 4796848 llmg_2058 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033313.1 2040903 R 416870 CDS YP_001033314.1 125624831 4798663 complement(2041527..2042204) 1 NC_009004.1 Protein of unknown function UPF0001, conserved hypothetical protein; hypothetical protein 2042204 4798663 llmg_2059 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033314.1 2041527 R 416870 CDS YP_001033315.1 125624832 4798073 complement(2042201..2043460) 1 NC_009004.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 2043460 ftsZ 4798073 ftsZ Lactococcus lactis subsp. cremoris MG1363 cell division protein FtsZ YP_001033315.1 2042201 R 416870 CDS YP_001033316.1 125624833 4797264 complement(2043490..2044860) 1 NC_009004.1 Cell division protein FtsA; High confidence in function and specificity; cell division protein ftsA 2044860 ftsA 4797264 ftsA Lactococcus lactis subsp. cremoris MG1363 cell division protein ftsA YP_001033316.1 2043490 R 416870 CDS YP_001033317.1 125624834 4798300 complement(2045022..2045891) 1 NC_009004.1 Uncharacterized protein, DegV family COG1307; Conserved hypothetical protein; hypothetical protein 2045891 4798300 llmg_2062 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033317.1 2045022 R 416870 CDS YP_001033318.1 125624835 4798072 complement(2046008..2046736) 1 NC_009004.1 23S ribosomal RNA methyltransferase, TrmH family; High confidence in function and specificity; tRNA/rRNA methyltransferase 2046736 trmH 4798072 trmH Lactococcus lactis subsp. cremoris MG1363 tRNA/rRNA methyltransferase YP_001033318.1 2046008 R 416870 CDS YP_001033319.1 125624836 4799046 complement(2046900..2048000) 1 NC_009004.1 Oxidoreductase, Glycine/D-amino acid oxidase; High confidence in function and specificity; oxidoreductase 2048000 4799046 llmg_2064 Lactococcus lactis subsp. cremoris MG1363 oxidoreductase YP_001033319.1 2046900 R 416870 CDS YP_001033320.1 125624837 4798065 complement(2048138..2048983) 1 NC_009004.1 Aldo/keto reductase; Family membership; aldo/keto reductase 2048983 4798065 llmg_2065 Lactococcus lactis subsp. cremoris MG1363 aldo/keto reductase YP_001033320.1 2048138 R 416870 CDS YP_001033321.1 125624838 4798452 complement(2048995..2050320) 1 NC_009004.1 Multidrug resistance protein B, permease of the Major facilitator superfamily, EmrB family; High confidence in function and specificity; multidrug resistance protein B 2050320 4798452 llmg_2066 Lactococcus lactis subsp. cremoris MG1363 multidrug resistance protein B YP_001033321.1 2048995 R 416870 CDS YP_001033322.1 125624839 4797374 complement(2050435..2051313) 1 NC_009004.1 HTH type transcriptional regulator, LysR family; Conserved hypothetical protein; LysR family transcriptional regulator 2051313 rlrB 4797374 rlrB Lactococcus lactis subsp. cremoris MG1363 LysR family transcriptional regulator YP_001033322.1 2050435 R 416870 CDS YP_001033323.1 125624840 4797132 complement(2051329..2051733) 1 NC_009004.1 HTH-type transcriptional regulator, MerR family; High confidence in function and specificity; MerR family transcriptional regulator 2051733 rmeA 4797132 rmeA Lactococcus lactis subsp. cremoris MG1363 MerR family transcriptional regulator YP_001033323.1 2051329 R 416870 CDS YP_001033324.1 125624841 4798018 complement(2051813..2053177) 1 NC_009004.1 PepC protein 2053177 pepC 4798018 pepC Lactococcus lactis subsp. cremoris MG1363 PepC protein YP_001033324.1 2051813 R 416870 CDS YP_001033325.1 125624842 4798037 complement(2053252..2053926) 1 NC_009004.1 Hypothetical protein in pepC 5'region (ORF 2, Metal- dependent phosphohydrolase, HD domain; High confidence in function and specificity; hypothetical protein 2053926 4798037 llmg_2070 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033325.1 2053252 R 416870 CDS YP_001033326.1 125624843 4797688 complement(2053944..2054447) 1 NC_009004.1 hypothetical protein 2054447 4797688 llmg_2071 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033326.1 2053944 R 416870 CDS YP_001033327.1 125624844 4798211 complement(2054401..2054514) 1 NC_009004.1 hypothetical protein 2054514 4798211 llmg_2072 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033327.1 2054401 R 416870 CDS YP_001033328.1 125624845 4797803 complement(2054584..2055264) 1 NC_009004.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 2055264 pfs 4797803 pfs Lactococcus lactis subsp. cremoris MG1363 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_001033328.1 2054584 R 416870 CDS YP_001033329.1 125624846 4796815 complement(2055292..2055570) 1 NC_009004.1 hypothetical protein 2055570 4796815 llmg_2074 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033329.1 2055292 R 416870 CDS YP_001033330.1 125624847 4797281 complement(2055563..2056147) 1 NC_009004.1 ADP-ribose pyrophosphatase, MutT/nudix family; High confidence in function and specificity; ADP-ribose pyrophosphatase 2056147 4797281 llmg_2075 Lactococcus lactis subsp. cremoris MG1363 ADP-ribose pyrophosphatase YP_001033330.1 2055563 R 416870 CDS YP_001033331.1 125624848 4797872 complement(2056248..2057624) 1 NC_009004.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 2057624 glmU 4797872 glmU Lactococcus lactis subsp. cremoris MG1363 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_001033331.1 2056248 R 416870 CDS YP_001033332.1 125624849 4797351 2057845..2058636 1 NC_009004.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 2058636 proC 4797351 proC Lactococcus lactis subsp. cremoris MG1363 pyrroline-5-carboxylate reductase YP_001033332.1 2057845 D 416870 CDS YP_001033333.1 125624850 4796767 complement(2058720..2059043) 1 NC_009004.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 2059043 rpsO 4796767 rpsO Lactococcus lactis subsp. cremoris MG1363 30S ribosomal protein S15 YP_001033333.1 2058720 R 416870 CDS YP_001033334.1 125624851 4797201 complement(2059160..2061037) 1 NC_009004.1 serine/threonine protein kinase 2061037 pknB 4797201 pknB Lactococcus lactis subsp. cremoris MG1363 serine/threonine protein kinase YP_001033334.1 2059160 R 416870 CDS YP_001033335.1 125624852 4796750 complement(2061037..2061813) 1 NC_009004.1 Protein phosphatase 2C-like; High confidence in function and specificity; phosphoprotein phosphatase 2061813 pppL 4796750 pppL Lactococcus lactis subsp. cremoris MG1363 phosphoprotein phosphatase YP_001033335.1 2061037 R 416870 CDS YP_001033336.1 125624853 4796892 complement(2061936..2063210) 1 NC_009004.1 Ribosomal RNA small subunit methyltransferase B, NusB/NOL1/NOP2/sun family; High confidence in function and specificity; ribosomal RNA small subunit methyltransferase B 2063210 sunL 4796892 sunL Lactococcus lactis subsp. cremoris MG1363 ribosomal RNA small subunit methyltransferase B YP_001033336.1 2061936 R 416870 CDS YP_001033337.1 125624854 4798734 complement(2064418..2065275) 1 NC_009004.1 phage lysin, cell wall hydrolase; High confidence in function and specificity; bacteriophage lysin 2065275 ps461 4798734 ps461 Lactococcus lactis subsp. cremoris MG1363 bacteriophage lysin YP_001033337.1 2064418 R 416870 CDS YP_001033338.1 125624855 4798043 complement(2065277..2065738) 1 NC_009004.1 Phage holin, LL-H; High confidence in function and specificity; bacteriophage holin 2065738 ps460 4798043 ps460 Lactococcus lactis subsp. cremoris MG1363 bacteriophage holin YP_001033338.1 2065277 R 416870 CDS YP_001033339.1 125624856 4798078 complement(2065754..2066101) 1 NC_009004.1 hypothetical protein 2066101 ps459 4798078 ps459 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033339.1 2065754 R 416870 CDS YP_001033340.1 125624857 4798345 complement(2066114..2066350) 1 NC_009004.1 hypothetical protein 2066350 ps458 4798345 ps458 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033340.1 2066114 R 416870 CDS YP_001033341.1 125624858 4797331 complement(2066366..2071219) 1 NC_009004.1 Phage minor structural protein, N-terminal, probable phage host specificity protein; High confidence in function and specificity; serine/threonine-rich protein precursor 2071219 ps457 4797331 ps457 Lactococcus lactis subsp. cremoris MG1363 serine/threonine-rich protein precursor YP_001033341.1 2066366 R 416870 CDS YP_001033342.1 125624859 4796578 complement(2071216..2072298) 1 NC_009004.1 phage tail component protein; High confidence in function and specificity; phage tail component 2072298 ps455 4796578 ps455 Lactococcus lactis subsp. cremoris MG1363 phage tail component YP_001033342.1 2071216 R 416870 CDS YP_001033343.1 125624860 4796627 complement(2072222..2072869) 1 NC_009004.1 tail protein; hypothetical protein 2072869 ps454 4796627 ps454 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033343.1 2072222 R 416870 CDS YP_001033344.1 125624861 4798432 complement(2072866..2078013) 1 NC_009004.1 phage tail component; High confidence in function and specificity; phage tail component 2078013 ps453 4798432 ps453 Lactococcus lactis subsp. cremoris MG1363 phage tail component YP_001033344.1 2072866 R 416870 CDS YP_001033345.1 125624862 4796568 complement(2078236..2078652) 1 NC_009004.1 phage tail component; High confidence in function and specificity; phage tail component 2078652 ps452 4796568 ps452 Lactococcus lactis subsp. cremoris MG1363 phage tail component YP_001033345.1 2078236 R 416870 CDS YP_001033346.1 125624863 4798240 complement(2078797..2079390) 1 NC_009004.1 Phage major tail protein; High confidence in function and specificity; phage major tail protein 2079390 ps451 4798240 ps451 Lactococcus lactis subsp. cremoris MG1363 phage major tail protein YP_001033346.1 2078797 R 416870 CDS YP_001033347.1 125624864 4798219 complement(2079421..2079816) 1 NC_009004.1 tail component protein; hypothetical protein 2079816 ps450 4798219 ps450 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033347.1 2079421 R 416870 CDS YP_001033348.1 125624865 4796738 complement(2079813..2080319) 1 NC_009004.1 Bacteriophage protein of unknown function DUF646; hypothetical protein 2080319 ps449 4796738 ps449 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033348.1 2079813 R 416870 CDS YP_001033349.1 125624866 4796993 complement(2080321..2080671) 1 NC_009004.1 hypothetical protein 2080671 ps448 4796993 ps448 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033349.1 2080321 R 416870 CDS YP_001033350.1 125624867 4797144 complement(2080646..2080969) 1 NC_009004.1 Uncharacterized phage protein (possible DNA packaging); hypothetical protein 2080969 ps447 4797144 ps447 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033350.1 2080646 R 416870 CDS YP_001033351.1 125624868 4798193 complement(2081170..2082384) 1 NC_009004.1 Phage major capsid protein, HK97 phage capsid family; High confidence in function and specificity; major head protein precursor 2082384 ps446 4798193 ps446 Lactococcus lactis subsp. cremoris MG1363 major head protein precursor YP_001033351.1 2081170 R 416870 CDS YP_001033352.1 125624869 4797092 complement(2082396..2083100) 1 NC_009004.1 Similar to ATP-dependent Clp protease proteolytic subunit; High confidence in function and specificity; hypothetical protein 2083100 ps445 4797092 ps445 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033352.1 2082396 R 416870 CDS YP_001033353.1 125624870 4797131 complement(2083146..2084318) 1 NC_009004.1 Phage portal protein, HK97 family; High confidence in function and specificity; phage portal protein 2084318 ps444 4797131 ps444 Lactococcus lactis subsp. cremoris MG1363 phage portal protein YP_001033353.1 2083146 R 416870 CDS YP_001033354.1 125624871 4796884 complement(2084321..2084530) 1 NC_009004.1 Conserved hypothetical protein; head-tail joining protein 2084530 ps443 4796884 ps443 Lactococcus lactis subsp. cremoris MG1363 head-tail joining protein YP_001033354.1 2084321 R 416870 CDS YP_001033355.1 125624872 4798215 complement(2084499..2086097) 1 NC_009004.1 Phage Terminase, large subunit; Conserved hypothetical protein; terminase large subunit 2086097 ps442 4798215 ps442 Lactococcus lactis subsp. cremoris MG1363 terminase large subunit YP_001033355.1 2084499 R 416870 CDS YP_001033356.1 125624873 4798025 complement(2087720..2088118) 1 NC_009004.1 phage terminase, small subunit, P27 family; phage terminase small subunit 2088118 ps440 4798025 ps440 Lactococcus lactis subsp. cremoris MG1363 phage terminase small subunit YP_001033356.1 2087720 R 416870 CDS YP_001033357.1 125624874 4796987 complement(2088300..2088818) 1 NC_009004.1 restriction endonuclease; hypothetical protein 2088818 ps439 4796987 ps439 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033357.1 2088300 R 416870 CDS YP_001033358.1 125624875 4798186 complement(2088822..2089112) 1 NC_009004.1 hypothetical protein 2089112 ps438 4798186 ps438 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033358.1 2088822 R 416870 CDS YP_001033359.1 125624876 4796951 complement(2089489..2089890) 1 NC_009004.1 Protein of unknown function DUF722; hypothetical protein 2089890 ps437 4796951 ps437 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033359.1 2089489 R 416870 CDS YP_001033360.1 125624877 4797125 complement(2089973..2090158) 1 NC_009004.1 Lambda repressor-like, DNA-binding protein; hypothetical protein 2090158 ps436 4797125 ps436 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033360.1 2089973 R 416870 CDS YP_001033361.1 125624878 4797139 complement(2090155..2090463) 1 NC_009004.1 hypothetical protein 2090463 ps435 4797139 ps435 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033361.1 2090155 R 416870 CDS YP_001033362.1 125624879 4797059 complement(2090646..2090819) 1 NC_009004.1 hypothetical protein 2090819 ps434 4797059 ps434 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033362.1 2090646 R 416870 CDS YP_001033363.1 125624880 4797053 complement(2090895..2091653) 1 NC_009004.1 PF01695: IstB-like ATP-binding protein; Conserved hypothetical protein; transposase helper protein for IS712H 2091653 4797053 llmg_2109 Lactococcus lactis subsp. cremoris MG1363 transposase helper protein for IS712H YP_001033363.1 2090895 R 416870 CDS YP_001033364.1 125624881 4797294 complement(2091665..2092888) 1 NC_009004.1 Conserved hypothetical protein; transposase for insertion sequence element IS712H 2092888 tnp712 4797294 tnp712 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS712H YP_001033364.1 2091665 R 416870 CDS YP_001033365.1 125624882 4797571 2093448..2093657 1 NC_009004.1 hypothetical protein 2093657 ps431 4797571 ps431 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033365.1 2093448 D 416870 CDS YP_001033366.1 125624883 4797051 complement(2093903..2094133) 1 NC_009004.1 hypothetical protein 2094133 ps430 4797051 ps430 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033366.1 2093903 R 416870 CDS YP_001033367.1 125624884 4798153 complement(2094152..2094490) 1 NC_009004.1 Protein of unknown function DUF1140; hypothetical protein 2094490 ps429 4798153 ps429 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033367.1 2094152 R 416870 CDS YP_001033368.1 125624885 4798157 complement(2094491..2094910) 1 NC_009004.1 Deoxyuridine 5'-triphosphate nucleotidohydrolase; High confidence in function and specificity; deoxyuridine 5'-triphosphate nucleotidohydrolase 2094910 ps428 4798157 ps428 Lactococcus lactis subsp. cremoris MG1363 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_001033368.1 2094491 R 416870 CDS YP_001033369.1 125624886 4798499 complement(2094907..2095464) 1 NC_009004.1 Protein of unknown function (DUF1642); hypothetical protein 2095464 ps427 4798499 ps427 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033369.1 2094907 R 416870 CDS YP_001033370.1 125624887 4796984 complement(2095480..2095716) 1 NC_009004.1 hypothetical protein 2095716 ps426 4796984 ps426 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033370.1 2095480 R 416870 CDS YP_001033371.1 125624888 4796838 complement(2095888..2096085) 1 NC_009004.1 hypothetical protein 2096085 ps425 4796838 ps425 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033371.1 2095888 R 416870 CDS YP_001033372.1 125624889 4797062 complement(2096086..2096352) 1 NC_009004.1 hypothetical protein 2096352 ps424 4797062 ps424 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033372.1 2096086 R 416870 CDS YP_001033373.1 125624890 4798228 complement(2096333..2096665) 1 NC_009004.1 hypothetical protein 2096665 ps423 4798228 ps423 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033373.1 2096333 R 416870 CDS YP_001033374.1 125624891 4797244 complement(2096680..2096964) 1 NC_009004.1 hypothetical protein 2096964 ps422 4797244 ps422 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033374.1 2096680 R 416870 CDS YP_001033375.1 125624892 4796608 complement(2096981..2097205) 1 NC_009004.1 hypothetical protein 2097205 ps421 4796608 ps421 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033375.1 2096981 R 416870 CDS YP_001033376.1 125624893 4796926 complement(2097312..2097551) 1 NC_009004.1 Protein of unknown function DUF1031; hypothetical protein 2097551 ps420 4796926 ps420 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033376.1 2097312 R 416870 CDS YP_001033377.1 125624894 4799104 complement(2097548..2097922) 1 NC_009004.1 Protein of unknown function DUF1064; hypothetical protein 2097922 ps419 4799104 ps419 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033377.1 2097548 R 416870 CDS YP_001033378.1 125624895 4797286 complement(2097919..2098644) 1 NC_009004.1 phage replication module protein; High confidence in function and specificity; hypothetical protein 2098644 ps418 4797286 ps418 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033378.1 2097919 R 416870 CDS YP_001033379.1 125624896 4796807 complement(2098644..2099426) 1 NC_009004.1 replisome organiser; High confidence in function and specificity; phage replication initiation protein 2099426 ps417 4796807 ps417 Lactococcus lactis subsp. cremoris MG1363 phage replication initiation protein YP_001033379.1 2098644 R 416870 CDS YP_001033380.1 125624897 4798574 complement(2099555..2099980) 1 NC_009004.1 Single-strand binding protein (SSB) (Helix- destabilizing protein); High confidence in function and specificity; single-strand binding protein ssB 2099980 ps416 4798574 ps416 Lactococcus lactis subsp. cremoris MG1363 single-strand binding protein ssB YP_001033380.1 2099555 R 416870 CDS YP_001033381.1 125624898 4798714 complement(2099973..2100107) 1 NC_009004.1 C-terminal end of prophage protein. Frameshift upstream in N-terminal region (1st 123aa's) corresponding to next ORF automatically called; translation initiation factor 2100107 4798714 llmg_2127 Lactococcus lactis subsp. cremoris MG1363 translation initiation factor YP_001033381.1 2099973 R 416870 CDS YP_001033382.1 125624899 4799100 complement(2100360..2100731) 1 NC_009004.1 translation initiation factor 2100731 ps415 4799100 ps415 Lactococcus lactis subsp. cremoris MG1363 translation initiation factor YP_001033382.1 2100360 R 416870 CDS YP_001033383.1 125624900 4798705 complement(2100740..2101135) 1 NC_009004.1 hypothetical protein 2101135 ps414 4798705 ps414 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033383.1 2100740 R 416870 CDS YP_001033384.1 125624901 4798699 complement(2101234..2101476) 1 NC_009004.1 hypothetical protein 2101476 ps413 4798699 ps413 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033384.1 2101234 R 416870 CDS YP_001033385.1 125624902 4798711 2101482..2101961 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 2101961 ps412 4798711 ps412 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033385.1 2101482 D 416870 CDS YP_001033386.1 125624903 4798716 complement(2101954..2102157) 1 NC_009004.1 hypothetical protein 2102157 ps411 4798716 ps411 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033386.1 2101954 R 416870 CDS YP_001033387.1 125624904 4798710 complement(2102253..2102522) 1 NC_009004.1 DNA binding protein; hypothetical protein 2102522 ps410 4798710 ps410 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033387.1 2102253 R 416870 CDS YP_001033388.1 125624905 4798706 complement(2102536..2103294) 1 NC_009004.1 Phage antirepressor protein; Conserved hypothetical protein; phage antirepressor protein 2103294 ps409 4798706 ps409 Lactococcus lactis subsp. cremoris MG1363 phage antirepressor protein YP_001033388.1 2102536 R 416870 CDS YP_001033389.1 125624906 4796621 complement(2103307..2103555) 1 NC_009004.1 Lambda repressor-like, DNA-binding, Helix-turn- helix motif, phage associated; Cro repressor 2103555 ps408 4796621 ps408 Lactococcus lactis subsp. cremoris MG1363 Cro repressor YP_001033389.1 2103307 R 416870 CDS YP_001033390.1 125624907 4796793 2103660..2103896 1 NC_009004.1 phage associated; hypothetical protein 2103896 ps407 4796793 ps407 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033390.1 2103660 D 416870 CDS YP_001033391.1 125624908 4796741 complement(2103868..2104089) 1 NC_009004.1 phage associated; hypothetical protein 2104089 ps406 4796741 ps406 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033391.1 2103868 R 416870 CDS YP_001033392.1 125624909 4798545 2104187..2104300 1 NC_009004.1 phage associated; hypothetical protein 2104300 ps405 4798545 ps405 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033392.1 2104187 D 416870 CDS YP_001033393.1 125624910 4796837 2104945..2105442 1 NC_009004.1 DNA-binding transcriptional regulator, Phage associated; High confidence in function and specificity; cI-like repressor 2105442 ps404 4796837 ps404 Lactococcus lactis subsp. cremoris MG1363 cI-like repressor YP_001033393.1 2104945 D 416870 CDS YP_001033394.1 125624911 4799010 2105448..2105882 1 NC_009004.1 phage associated; hypothetical protein 2105882 ps403 4799010 ps403 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033394.1 2105448 D 416870 CDS YP_001033395.1 125624912 4798725 2105896..2106231 1 NC_009004.1 Phage associated; hypothetical protein 2106231 ps402 4798725 ps402 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033395.1 2105896 D 416870 CDS YP_001033396.1 125624913 4796844 2106266..2107480 1 NC_009004.1 Phage integrase; High confidence in function and specificity; phage integrase 2107480 ps401 4796844 ps401 Lactococcus lactis subsp. cremoris MG1363 phage integrase YP_001033396.1 2106266 D 416870 CDS YP_001033397.1 125624914 4799108 complement(2107775..2108281) 1 NC_009004.1 Protein of unknown function DUF322, Protein of unknown function (DUF322); Conserved hypothetical protein; 20-kDa protein 2108281 4799108 llmg_2143 Lactococcus lactis subsp. cremoris MG1363 20-kDa protein YP_001033397.1 2107775 R 416870 CDS YP_001033398.1 125624915 4799124 complement(2108291..2108479) 1 NC_009004.1 hypothetical protein 2108479 4799124 llmg_2144 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033398.1 2108291 R 416870 CDS YP_001033399.1 125624916 4799126 complement(2108490..2109050) 1 NC_009004.1 --; hypothetical protein 2109050 4799126 llmg_2145 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033399.1 2108490 R 416870 CDS YP_001033400.1 125624917 4799115 complement(2109078..2109320) 1 NC_009004.1 -; hypothetical protein 2109320 4799115 llmg_2146 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033400.1 2109078 R 416870 CDS YP_001033401.1 125624918 4799113 complement(2109555..2110526) 1 NC_009004.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 2110526 fmt 4799113 fmt Lactococcus lactis subsp. cremoris MG1363 methionyl-tRNA formyltransferase YP_001033401.1 2109555 R 416870 CDS YP_001033402.1 125624919 4798490 complement(2110523..2110987) 1 NC_009004.1 3-demethylubiquinone-9 3-methyltransferase; hypothetical protein 2110987 4798490 llmg_2148 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033402.1 2110523 R 416870 CDS YP_001033403.1 125624920 4797124 complement(2110953..2111474) 1 NC_009004.1 NUDIX hydrolase; Conserved hypothetical protein; Nudix hydrolase 2111474 4797124 llmg_2149 Lactococcus lactis subsp. cremoris MG1363 Nudix hydrolase YP_001033403.1 2110953 R 416870 CDS YP_001033404.1 125624921 4797054 complement(2111488..2111862) 1 NC_009004.1 hypothetical protein 2111862 4797054 llmg_2150 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033404.1 2111488 R 416870 CDS YP_001033405.1 125624922 4796575 complement(2111849..2112595) 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 2112595 4796575 llmg_2151 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033405.1 2111849 R 416870 CDS YP_001033406.1 125624923 4797042 complement(2112728..2113069) 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 2113069 4797042 llmg_2152 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033406.1 2112728 R 416870 CDS YP_001033407.1 125624924 4797106 complement(2113093..2115438) 1 NC_009004.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 2115438 priA 4797106 priA Lactococcus lactis subsp. cremoris MG1363 primosome assembly protein PriA YP_001033407.1 2113093 R 416870 CDS YP_001033408.1 125624925 4796949 complement(2115615..2115968) 1 NC_009004.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 2115968 rpoZ 4796949 rpoZ Lactococcus lactis subsp. cremoris MG1363 DNA-directed RNA polymerase subunit omega YP_001033408.1 2115615 R 416870 CDS YP_001033409.1 125624926 4797566 complement(2116037..2116654) 1 NC_009004.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 2116654 gmk 4797566 gmk Lactococcus lactis subsp. cremoris MG1363 guanylate kinase YP_001033409.1 2116037 R 416870 CDS YP_001033410.1 125624927 4797527 complement(2116803..2118398) 1 NC_009004.1 protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP; phosphodiesterase 2118398 4797527 llmg_2156 Lactococcus lactis subsp. cremoris MG1363 phosphodiesterase YP_001033410.1 2116803 R 416870 CDS YP_001033411.1 125624928 4796882 complement(2118632..2119345) 1 NC_009004.1 Glucosamine-6-phosphate deaminase; High confidence in function and specificity; 6-phosphogluconolactonase 2119345 nagB2 4796882 nagB2 Lactococcus lactis subsp. cremoris MG1363 6-phosphogluconolactonase YP_001033411.1 2118632 R 416870 CDS YP_001033412.1 125624929 4797026 complement(2119449..2119541) 1 NC_009004.1 duplication of the C-terminal end of metK; hypothetical protein 2119541 4797026 llmg_2158 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033412.1 2119449 R 416870 CDS YP_001033413.1 125624930 4798112 complement(2119619..2119711) 1 NC_009004.1 duplication of the C-terminal end of metK; hypothetical protein 2119711 4798112 llmg_2159 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033413.1 2119619 R 416870 CDS YP_001033414.1 125624931 4798180 complement(2119789..2120988) 1 NC_009004.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 2120988 metK 4798180 metK Lactococcus lactis subsp. cremoris MG1363 S-adenosylmethionine synthetase YP_001033414.1 2119789 R 416870 CDS YP_001033415.1 125624932 4798893 complement(2121533..2122726) 1 NC_009004.1 cyclopropane-fatty-acyl-phospholipid synthase 2122726 cfa 4798893 cfa Lactococcus lactis subsp. cremoris MG1363 cyclopropane-fatty-acyl-phospholipid synthase YP_001033415.1 2121533 R 416870 CDS YP_001033416.1 125624933 4799099 2122883..2123635 1 NC_009004.1 BirA bifunctional protein; High confidence in function and specificity; acetyl-CoA carboxylase ligase / biotin operon repressor bifunctional protein 2123635 birA2 4799099 birA2 Lactococcus lactis subsp. cremoris MG1363 acetyl-CoA carboxylase ligase / biotin operon repressor bifunctional protein YP_001033416.1 2122883 D 416870 CDS YP_001033417.1 125624934 4798831 complement(2123763..2124227) 1 NC_009004.1 contains PspC domain; hypothetical protein 2124227 4798831 llmg_2163 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033417.1 2123763 R 416870 CDS YP_001033418.1 125624935 4797034 complement(2124563..2125675) 1 NC_009004.1 hypothetical protein 2125675 4797034 llmg_2164 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033418.1 2124563 R 416870 CDS YP_001033419.1 125624936 4797015 complement(2125886..2127502) 1 NC_009004.1 peptidoglycan hydrolase; High confidence in function and specificity; N-acetylmuramoyl-L-alanine amidase 2127502 acmB 4797015 acmB Lactococcus lactis subsp. cremoris MG1363 N-acetylmuramoyl-L-alanine amidase YP_001033419.1 2125886 R 416870 CDS YP_001033420.1 125624937 4798307 complement(2129181..2130077) 1 NC_009004.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 2130077 fbaA 4798307 fbaA Lactococcus lactis subsp. cremoris MG1363 fructose-bisphosphate aldolase YP_001033420.1 2129181 R 416870 CDS YP_001033421.1 125624938 4797444 complement(2136110..2136769) 1 NC_009004.1 Protein of unknown function; Conserved hypothetical protein; hypothetical protein 2136769 4797444 llmg_2168 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033421.1 2136110 R 416870 CDS YP_001033422.1 125624939 4796964 complement(2136874..2138814) 1 NC_009004.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 2138814 thrS 4796964 thrS Lactococcus lactis subsp. cremoris MG1363 threonyl-tRNA synthetase YP_001033422.1 2136874 R 416870 CDS YP_001033423.1 125624940 4797584 complement(2139513..2139830) 1 NC_009004.1 High confidence in function and specificity; ribonucleoside-diphosphate reductase 2139830 4797584 llmg_2170 Lactococcus lactis subsp. cremoris MG1363 ribonucleoside-diphosphate reductase YP_001033423.1 2139513 R 416870 CDS YP_001033424.1 125624941 4796927 complement(2139888..2141150) 1 NC_009004.1 High confidence in function and specificity; Mn and Fe transporters 2141150 mntA 4796927 mntA Lactococcus lactis subsp. cremoris MG1363 Mn and Fe transporters YP_001033424.1 2139888 R 416870 CDS YP_001033425.1 125624942 4797481 complement(2141256..2141864) 1 NC_009004.1 Conserved hypothetical protein; nitroreductase 2141864 4797481 llmg_2172 Lactococcus lactis subsp. cremoris MG1363 nitroreductase YP_001033425.1 2141256 R 416870 CDS YP_001033426.1 125624943 4796903 2142091..2142381 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 2142381 4796903 llmg_2173 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033426.1 2142091 D 416870 CDS YP_001033427.1 125624944 4796744 2142477..2143238 1 NC_009004.1 Conserved hypothetical protein; transposase for insertion sequence element IS904I 2143238 tnp904 4796744 tnp904 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS904I YP_001033427.1 2142477 D 416870 CDS YP_001033428.1 125624945 4797003 complement(2144101..2144670) 1 NC_009004.1 Function unclear; hypothetical protein 2144670 4797003 llmg_2175 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033428.1 2144101 R 416870 CDS YP_001033429.1 125624946 4797268 complement(2144746..2145381) 1 NC_009004.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 2145381 upp 4797268 upp Lactococcus lactis subsp. cremoris MG1363 uracil phosphoribosyltransferase YP_001033429.1 2144746 R 416870 CDS YP_001033430.1 125624947 4797164 complement(2145583..2146722) 1 NC_009004.1 Sodium/hydrogen exchanger family; High confidence in function and specificity; Na+/H+ antiporter 2146722 nah 4797164 nah Lactococcus lactis subsp. cremoris MG1363 Na+/H+ antiporter YP_001033430.1 2145583 R 416870 CDS YP_001033431.1 125624948 4798149 complement(2148432..2149520) 1 NC_009004.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 2149520 metB1 4798149 metB1 Lactococcus lactis subsp. cremoris MG1363 cystathionine gamma-synthase YP_001033431.1 2148432 R 416870 CDS YP_001033432.1 125624949 4796856 complement(2149551..2150510) 1 NC_009004.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 2150510 metA 4796856 metA Lactococcus lactis subsp. cremoris MG1363 homoserine O-succinyltransferase YP_001033432.1 2149551 R 416870 CDS YP_001033433.1 125624950 4797454 complement(2150648..2151205) 1 NC_009004.1 hypothetical protein 2151205 4797454 llmg_2183 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033433.1 2150648 R 416870 CDS YP_001033434.1 125624951 4797166 complement(2151214..2152122) 1 NC_009004.1 hypothetical protein 2152122 4797166 llmg_2184 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033434.1 2151214 R 416870 CDS YP_001033435.1 125624952 4798297 complement(2152257..2153126) 1 NC_009004.1 Galactose mutarotase-like, Aldose 1-epimerase; galactose mutarotase related enzyme 2153126 lacX 4798297 lacX Lactococcus lactis subsp. cremoris MG1363 galactose mutarotase related enzyme YP_001033435.1 2152257 R 416870 CDS YP_001033436.1 125624953 4797654 complement(2153217..2154161) 1 NC_009004.1 Metal-dependent phosphohydrolase, HD subdomain; Conserved hypothetical protein; CMP-binding factor 2154161 cbf 4797654 cbf Lactococcus lactis subsp. cremoris MG1363 CMP-binding factor YP_001033436.1 2153217 R 416870 CDS YP_001033437.1 125624954 4797648 complement(2154235..2155533) 1 NC_009004.1 Protein of unknown function DUF195, RmuC family; hypothetical protein 2155533 4797648 llmg_2187 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033437.1 2154235 R 416870 CDS YP_001033438.1 125624955 4798612 complement(2155543..2155812) 1 NC_009004.1 hypothetical protein 2155812 4798612 llmg_2188 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033438.1 2155543 R 416870 CDS YP_001033439.1 125624956 4797188 complement(2155879..2156052) 1 NC_009004.1 Conserved hypothetical protein; tunicamycin resistance protein 2156052 tmrB 4797188 tmrB Lactococcus lactis subsp. cremoris MG1363 tunicamycin resistance protein YP_001033439.1 2155879 R 416870 CDS YP_001033440.1 125624957 4796920 complement(2156049..2156711) 1 NC_009004.1 Ribulose-phosphate 3-epimerase; High confidence in function and specificity; ribulose-phosphate 3-epimerase 2156711 rpe 4796920 rpe Lactococcus lactis subsp. cremoris MG1363 ribulose-phosphate 3-epimerase YP_001033440.1 2156049 R 416870 CDS YP_001033441.1 125624958 4797291 complement(2156785..2157042) 1 NC_009004.1 hypothetical protein 2157042 4797291 llmg_2191 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033441.1 2156785 R 416870 CDS YP_001033442.1 125624959 4798510 complement(2157039..2157293) 1 NC_009004.1 hypothetical protein 2157293 4798510 llmg_2192 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033442.1 2157039 R 416870 CDS YP_001033443.1 125624960 4798051 complement(2157265..2158188) 1 NC_009004.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 2158188 4798051 llmg_2193 Lactococcus lactis subsp. cremoris MG1363 ribosome-associated GTPase YP_001033443.1 2157265 R 416870 CDS YP_001033444.1 125624961 4798120 complement(2158249..2159322) 1 NC_009004.1 Region start changed from 2159382 to 2159322 (-60 bases); hypothetical protein 2159322 4798120 llmg_2194 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033444.1 2158249 R 416870 CDS YP_001033445.1 125624962 4799009 complement(2159623..2162016) 1 NC_009004.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 2162016 pheT 4799009 pheT Lactococcus lactis subsp. cremoris MG1363 phenylalanyl-tRNA synthetase subunit beta YP_001033445.1 2159623 R 416870 CDS YP_001033446.1 125624963 4798544 complement(2162127..2163164) 1 NC_009004.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 2163164 pheS 4798544 pheS Lactococcus lactis subsp. cremoris MG1363 phenylalanyl-tRNA synthetase subunit alpha YP_001033446.1 2162127 R 416870 CDS YP_001033447.1 125624964 4797867 2163648..2164103 1 NC_009004.1 Probable phenolic acid decarboxylase; High confidence in function and specificity; PadC protein 2164103 padC 4797867 padC Lactococcus lactis subsp. cremoris MG1363 PadC protein YP_001033447.1 2163648 D 416870 CDS YP_001033448.1 125624965 4799074 2164419..2164958 1 NC_009004.1 Transcriptional regulator PadR-like; transcriptional repressor of padC 2164958 padR 4799074 padR Lactococcus lactis subsp. cremoris MG1363 transcriptional repressor of padC YP_001033448.1 2164419 D 416870 CDS YP_001033449.1 125624966 4799073 2165127..2166605 1 NC_009004.1 Chitinase II, Glycosyl hydrolases family 18; Conserved hypothetical protein; acidic endochitinase precursor 2166605 chiC 4799073 chiC Lactococcus lactis subsp. cremoris MG1363 acidic endochitinase precursor YP_001033449.1 2165127 D 416870 CDS YP_001033450.1 125624967 4797027 2166626..2167288 1 NC_009004.1 Chitin-binding, domain 3; chitin binding protein 2167288 chb 4797027 chb Lactococcus lactis subsp. cremoris MG1363 chitin binding protein YP_001033450.1 2166626 D 416870 CDS YP_001033451.1 125624968 4796977 complement(2167331..2168623) 1 NC_009004.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 2168623 purA 4796977 purA Lactococcus lactis subsp. cremoris MG1363 adenylosuccinate synthetase YP_001033451.1 2167331 R 416870 CDS YP_001033452.1 125624969 4797731 complement(2168798..2168911) 1 NC_009004.1 hypothetical protein 2168911 4797731 llmg_2202 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033452.1 2168798 R 416870 CDS YP_001033453.1 125624970 4798254 complement(2168989..2169600) 1 NC_009004.1 cadmium resistance transporter family protein; cadmium resistance protein 2169600 cadD 4798254 cadD Lactococcus lactis subsp. cremoris MG1363 cadmium resistance protein YP_001033453.1 2168989 R 416870 CDS YP_001033454.1 125624971 4797626 2169764..2170630 1 NC_009004.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 2170630 hslO 4797626 hslO Lactococcus lactis subsp. cremoris MG1363 Hsp33-like chaperonin YP_001033454.1 2169764 D 416870 CDS YP_001033455.1 125624972 4796618 2170685..2171206 1 NC_009004.1 Bacterial bifunctional deaminase-reductase, C- terminal; dihydrofolate reductase 2171206 4796618 llmg_2205 Lactococcus lactis subsp. cremoris MG1363 dihydrofolate reductase YP_001033455.1 2170685 D 416870 CDS YP_001033456.1 125624973 4798075 2171541..2172818 1 NC_009004.1 hypothetical protein 2172818 4798075 llmg_2206 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033456.1 2171541 D 416870 CDS YP_001033457.1 125624974 4798475 2172828..2173400 1 NC_009004.1 hypothetical protein 2173400 4798475 llmg_2207 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033457.1 2172828 D 416870 CDS YP_001033458.1 125624975 4797190 2173443..2173835 1 NC_009004.1 hypothetical protein 2173835 4797190 llmg_2208 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033458.1 2173443 D 416870 CDS YP_001033459.1 125624976 4798097 2173947..2174951 1 NC_009004.1 Dihydrouridine synthase TIM-barrel protein nifR3; Conserved hypothetical protein; tRNA-dihydrouridine synthase B 2174951 4798097 llmg_2209 Lactococcus lactis subsp. cremoris MG1363 tRNA-dihydrouridine synthase B YP_001033459.1 2173947 D 416870 CDS YP_001033460.1 125624977 4798408 2175017..2175109 1 NC_009004.1 hypothetical protein 2175109 4798408 llmg_2210 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033460.1 2175017 D 416870 CDS YP_001033461.1 125624978 4798615 2175267..2175497 1 NC_009004.1 hypothetical protein 2175497 4798615 llmg_2211 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033461.1 2175267 D 416870 CDS YP_001033462.1 125624979 4798740 complement(2175537..2176421) 1 NC_009004.1 Protein of unknown function DUF161; hypothetical protein 2176421 4798740 llmg_2212 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033462.1 2175537 R 416870 CDS YP_001033463.1 125624980 4798953 complement(2176572..2177447) 1 NC_009004.1 Protein of unknown function DUF161; hypothetical protein 2177447 4798953 llmg_2213 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033463.1 2176572 R 416870 CDS YP_001033464.1 125624981 4798604 complement(2177551..2178480) 1 NC_009004.1 Protein of unknown function DUF161; hypothetical protein 2178480 4798604 llmg_2214 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033464.1 2177551 R 416870 CDS YP_001033465.1 125624982 4798611 complement(2178461..2180233) 1 NC_009004.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 2180233 aspS 4798611 aspS Lactococcus lactis subsp. cremoris MG1363 aspartyl-tRNA synthetase YP_001033465.1 2178461 R 416870 CDS YP_001033466.1 125624983 4798409 complement(2180297..2180665) 1 NC_009004.1 Hypothetical 12.4 kDa HIT-like protein in PSBAII 5'region (ORF 1); High confidence in function and specificity; cell-cycle regulation histidine triad protein 2180665 4798409 llmg_2216 Lactococcus lactis subsp. cremoris MG1363 cell-cycle regulation histidine triad protein YP_001033466.1 2180297 R 416870 CDS YP_001033467.1 125624984 4798614 complement(2180691..2181983) 1 NC_009004.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 2181983 hisS 4798614 hisS Lactococcus lactis subsp. cremoris MG1363 histidyl-tRNA synthetase YP_001033467.1 2180691 R 416870 CDS YP_001033468.1 125624985 4796650 complement(2182296..2183456) 1 NC_009004.1 Transcriptional activator Rgg/GadR/MutR, C- terminal; hypothetical protein 2183456 4796650 llmg_2218 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033468.1 2182296 R 416870 CDS YP_001033469.1 125624986 4797542 complement(2183700..2184023) 1 NC_009004.1 Region start changed from 2184026 to 2184023 (-3 bases); hypothetical protein 2184023 4797542 llmg_2219 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033469.1 2183700 R 416870 CDS YP_001033470.1 125624987 4797552 complement(2184088..2184165) 1 NC_009004.1 Region start changed from 2184420 to 2184165 (-255 bases); hypothetical protein 2184165 4797552 llmg_2220 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033470.1 2184088 R 416870 CDS YP_001033471.1 125624988 4797559 complement(2184552..2184896) 1 NC_009004.1 Region start changed from 2184947 to 2184896 (-51 bases); hypothetical protein 2184896 4797559 llmg_2221 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033471.1 2184552 R 416870 CDS YP_001033472.1 125624989 4797560 complement(2185006..2185329) 1 NC_009004.1 Region start changed from 2185332 to 2185329 (-3 bases); hypothetical protein 2185329 4797560 llmg_2222 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033472.1 2185006 R 416870 CDS YP_001033473.1 125624990 4797586 complement(2185333..2186193) 1 NC_009004.1 hypothetical protein 2186193 4797586 llmg_2223 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033473.1 2185333 R 416870 CDS YP_001033474.1 125624991 4797595 complement(2186432..2187004) 1 NC_009004.1 High confidence in function and specificity; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 2187004 pgsA 4797595 pgsA Lactococcus lactis subsp. cremoris MG1363 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_001033474.1 2186432 R 416870 CDS YP_001033475.1 125624992 4798380 complement(2187046..2187942) 1 NC_009004.1 Lambda repressor-like, DNA-binding; hypothetical protein 2187942 4798380 llmg_2225 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033475.1 2187046 R 416870 CDS YP_001033476.1 125624993 4798338 complement(2188155..2189438) 1 NC_009004.1 High confidence in function and specificity; M16 family peptidase 2189438 4798338 llmg_2226 Lactococcus lactis subsp. cremoris MG1363 M16 family peptidase YP_001033476.1 2188155 R 416870 CDS YP_001033477.1 125624994 4798343 complement(2189428..2190714) 1 NC_009004.1 High confidence in function and specificity; hypothetical protein 2190714 4798343 llmg_2227 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033477.1 2189428 R 416870 CDS YP_001033478.1 125624995 4798660 2190912..2191274 1 NC_009004.1 RNA-binding S4; hypothetical protein 2191274 4798660 llmg_2228 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033478.1 2190912 D 416870 CDS YP_001033479.1 125624996 4797336 2191274..2192353 1 NC_009004.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 2192353 recF 4797336 recF Lactococcus lactis subsp. cremoris MG1363 recombination protein F YP_001033479.1 2191274 D 416870 CDS YP_001033480.1 125624997 4796697 complement(2192458..2192826) 1 NC_009004.1 Carboxymuconolactone decarboxylase; High confidence in function and specificity; gamma-carboxymuconolactone decarboxylase 2192826 pcaC 4796697 pcaC Lactococcus lactis subsp. cremoris MG1363 gamma-carboxymuconolactone decarboxylase YP_001033480.1 2192458 R 416870 CDS YP_001033481.1 125624998 4798143 2192903..2193280 1 NC_009004.1 DNA binding; Conserved hypothetical protein; MerR family transcriptional regulator 2193280 rmeD 4798143 rmeD Lactococcus lactis subsp. cremoris MG1363 MerR family transcriptional regulator YP_001033481.1 2192903 D 416870 CDS YP_001033482.1 125624999 4797813 complement(2193297..2194262) 1 NC_009004.1 Bacterial protein of unknown function (DUF915); hypothetical protein 2194262 4797813 llmg_2232 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033482.1 2193297 R 416870 CDS YP_001033483.1 125625000 4798346 complement(2194374..2195354) 1 NC_009004.1 NAD dependent epimerase/dehydratase; High confidence in function and specificity; GalE protein 2195354 galE 4798346 galE Lactococcus lactis subsp. cremoris MG1363 GalE protein YP_001033483.1 2194374 R 416870 CDS YP_001033484.1 125625001 4799060 complement(2195471..2196952) 1 NC_009004.1 catalyzes the formation of alpha-D-glucose 1-phosphate and UDP-galactose from UDP-glucose and alpha-D-galactose 1-phosphate in galactose metabolism; galactose-1-phosphate uridylyltransferase 2196952 galT 4799060 galT Lactococcus lactis subsp. cremoris MG1363 galactose-1-phosphate uridylyltransferase YP_001033484.1 2195471 R 416870 CDS YP_001033485.1 125625002 4797662 complement(2197125..2198324) 1 NC_009004.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 2198324 galK 4797662 galK Lactococcus lactis subsp. cremoris MG1363 galactokinase YP_001033485.1 2197125 R 416870 CDS YP_001033486.1 125625003 4797632 complement(2198351..2199370) 1 NC_009004.1 Galactose mutarotase-like; High confidence in function and specificity; aldose 1-epimerase 2199370 galM 4797632 galM Lactococcus lactis subsp. cremoris MG1363 aldose 1-epimerase YP_001033486.1 2198351 R 416870 CDS YP_001033487.1 125625004 4797641 complement(2199576..2200964) 1 NC_009004.1 Sodium:galactoside symporter; Conserved hypothetical protein; galactose permease 2200964 galP 4797641 galP Lactococcus lactis subsp. cremoris MG1363 galactose permease YP_001033487.1 2199576 R 416870 CDS YP_001033488.1 125625005 4797651 complement(2201271..2202023) 1 NC_009004.1 transcriptional regulator, PF01380: Sugar isomerase (SIS domain); hypothetical protein 2202023 4797651 llmg_2238 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033488.1 2201271 R 416870 CDS YP_001033489.1 125625006 4798095 complement(2203231..2204370) 1 NC_009004.1 IPR006417 Nicotinamide-nucleotide adenylyltransferase, TIGR01526: nicotinamide-nucleotide adenylyltransferase, no DNA binding HTH-motif; Conserved hypothetical protein; nicotinamide-nucleotide adenylyltransferase 2204370 nadR 4798095 nadR Lactococcus lactis subsp. cremoris MG1363 nicotinamide-nucleotide adenylyltransferase YP_001033489.1 2203231 R 416870 CDS YP_001033490.1 125625007 4798500 complement(2204357..2205334) 1 NC_009004.1 PF02826: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; Family membership; hypothetical protein 2205334 4798500 llmg_2242 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033490.1 2204357 R 416870 CDS YP_001033491.1 125625008 4797532 complement(2205532..2206824) 1 NC_009004.1 PF01136: Peptidase U32, protease; hypothetical protein 2206824 4797532 llmg_2243 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033491.1 2205532 R 416870 CDS YP_001033492.1 125625009 4797523 complement(2207148..2208119) 1 NC_009004.1 PF01136: Peptidase U32, protease; hypothetical protein 2208119 4797523 llmg_2244 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033492.1 2207148 R 416870 CDS YP_001033493.1 125625010 4798876 2208291..2208572 1 NC_009004.1 hypothetical protein 2208572 4798876 llmg_2245 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033493.1 2208291 D 416870 CDS YP_001033494.1 125625011 4798888 complement(2208602..2209423) 1 NC_009004.1 Conserved hypothetical protein; rRNA (guanine-N1-)-methyltransferase 2209423 rrmA 4798888 rrmA Lactococcus lactis subsp. cremoris MG1363 rRNA (guanine-N1-)-methyltransferase YP_001033494.1 2208602 R 416870 CDS YP_001033495.1 125625012 4798381 complement(2210138..2210863) 1 NC_009004.1 hypothetical protein 2210863 4798381 llmg_2247 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033495.1 2210138 R 416870 CDS YP_001033496.1 125625013 4798898 complement(2210856..2212178) 1 NC_009004.1 Hypothetical phage protein; abortive phage resistance 2212178 4798898 llmg_2248 Lactococcus lactis subsp. cremoris MG1363 abortive phage resistance YP_001033496.1 2210856 R 416870 CDS YP_001033497.1 125625014 4798912 complement(2212625..2212957) 1 NC_009004.1 hypothetical protein 2212957 4798912 llmg_2249 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033497.1 2212625 R 416870 CDS YP_001033498.1 125625015 4798923 complement(2212957..2213397) 1 NC_009004.1 PF03592: Terminase small subunit; Conserved hypothetical protein; terminase small subunit 2213397 ps519 4798923 ps519 Lactococcus lactis subsp. cremoris MG1363 terminase small subunit YP_001033498.1 2212957 R 416870 CDS YP_001033499.1 125625016 4798309 complement(2213530..2214072) 1 NC_009004.1 phage protein by Glimmer/Critica 2214072 ps518 4798309 ps518 Lactococcus lactis subsp. cremoris MG1363 phage protein by Glimmer/Critica YP_001033499.1 2213530 R 416870 CDS YP_001033500.1 125625017 4798311 complement(2214289..2215917) 1 NC_009004.1 Conserved hypothetical protein; DNA primase 2215917 ps517 4798311 ps517 Lactococcus lactis subsp. cremoris MG1363 DNA primase YP_001033500.1 2214289 R 416870 CDS YP_001033501.1 125625018 4798026 complement(2215928..2216722) 1 NC_009004.1 phage protein by Glimmer/Critica 2216722 ps516 4798026 ps516 Lactococcus lactis subsp. cremoris MG1363 phage protein by Glimmer/Critica YP_001033501.1 2215928 R 416870 CDS YP_001033502.1 125625019 4797287 complement(2216719..2217054) 1 NC_009004.1 phage protein by Glimmer/Critica 2217054 ps515 4797287 ps515 Lactococcus lactis subsp. cremoris MG1363 phage protein by Glimmer/Critica YP_001033502.1 2216719 R 416870 CDS YP_001033503.1 125625020 4797174 complement(2217124..2217363) 1 NC_009004.1 phage protein by Glimmer/Critica 2217363 ps514 4797174 ps514 Lactococcus lactis subsp. cremoris MG1363 phage protein by Glimmer/Critica YP_001033503.1 2217124 R 416870 CDS YP_001033504.1 125625021 4797176 complement(2217401..2217682) 1 NC_009004.1 hypothetical protein 2217682 ps513 4797176 ps513 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033504.1 2217401 R 416870 CDS YP_001033505.1 125625022 4797192 complement(2217675..2217800) 1 NC_009004.1 hypothetical protein 2217800 ps512 4797192 ps512 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033505.1 2217675 R 416870 CDS YP_001033506.1 125625023 4797814 complement(2217816..2217911) 1 NC_009004.1 hypothetical protein 2217911 ps511 4797814 ps511 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033506.1 2217816 R 416870 CDS YP_001033507.1 125625024 4797822 complement(2217904..2218107) 1 NC_009004.1 hypothetical protein 2218107 ps510 4797822 ps510 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033507.1 2217904 R 416870 CDS YP_001033508.1 125625025 4797821 complement(2218104..2218625) 1 NC_009004.1 phage protein by Glimmer/Critica 2218625 ps509 4797821 ps509 Lactococcus lactis subsp. cremoris MG1363 phage protein by Glimmer/Critica YP_001033508.1 2218104 R 416870 CDS YP_001033509.1 125625026 4798030 complement(2218884..2219549) 1 NC_009004.1 phage protein by Glimmer/Critica 2219549 ps508 4798030 ps508 Lactococcus lactis subsp. cremoris MG1363 phage protein by Glimmer/Critica YP_001033509.1 2218884 R 416870 CDS YP_001033510.1 125625027 4798004 2220104..2220646 1 NC_009004.1 bacteriophage repressor, PF01381: Helix- turn-helix , IPR010982: Lambda repressor-like, DNA- binding; hypothetical protein 2220646 ps507 4798004 ps507 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033510.1 2220104 D 416870 CDS YP_001033511.1 125625028 4797907 2221547..2222281 1 NC_009004.1 hypothetical protein 2222281 ps506 4797907 ps506 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033511.1 2221547 D 416870 CDS YP_001033512.1 125625029 4797828 2222487..2222672 1 NC_009004.1 hypothetical protein 2222672 ps505 4797828 ps505 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033512.1 2222487 D 416870 CDS YP_001033513.1 125625030 4797301 2222859..2223923 1 NC_009004.1 hypothetical protein 2223923 ps504 4797301 ps504 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033513.1 2222859 D 416870 CDS YP_001033514.1 125625031 4797156 2224575..2224889 1 NC_009004.1 hypothetical protein 2224889 ps503 4797156 ps503 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033514.1 2224575 D 416870 CDS YP_001033515.1 125625032 4798505 2225693..2225887 1 NC_009004.1 hypothetical protein 2225887 ps502 4798505 ps502 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033515.1 2225693 D 416870 CDS YP_001033516.1 125625033 4798002 2226384..2227565 1 NC_009004.1 PF00589: Phage integrase; Conserved hypothetical protein; phage integrase 2227565 ps501 4798002 ps501 Lactococcus lactis subsp. cremoris MG1363 phage integrase YP_001033516.1 2226384 D 416870 CDS YP_001033517.1 125625034 4798260 2227778..2228404 1 NC_009004.1 PF03932: CutC family; Conserved hypothetical protein; copper homeostasis protein cutC 2228404 cutC 4798260 cutC Lactococcus lactis subsp. cremoris MG1363 copper homeostasis protein cutC YP_001033517.1 2227778 D 416870 CDS YP_001033518.1 125625035 4798847 complement(2228437..2229456) 1 NC_009004.1 PF05975: Bacterial ABC transporter protein EcsB; Family membership; ABC transporter ATP-binding protein 2229456 ecsB 4798847 ecsB Lactococcus lactis subsp. cremoris MG1363 ABC transporter ATP-binding protein YP_001033518.1 2228437 R 416870 CDS YP_001033519.1 125625036 4798619 complement(2229449..2230219) 1 NC_009004.1 PF00005: ABC transporter; Conserved hypothetical protein; ABC transporter ATP-binding protein 2230219 ecsA 4798619 ecsA Lactococcus lactis subsp. cremoris MG1363 ABC transporter ATP-binding protein YP_001033519.1 2229449 R 416870 CDS YP_001033520.1 125625037 4797563 complement(2230238..2232016) 1 NC_009004.1 IPR004129: Glycerophosphoryl diester phosphodiesterase , Glycerophosphoryl diester phosphodiesterase; hypothetical protein 2232016 4797563 llmg_2272 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033520.1 2230238 R 416870 CDS YP_001033521.1 125625038 4798540 2232315..2232713 1 NC_009004.1 Histidine triad protein, PF01230: HIT domain; hypothetical protein 2232713 4798540 llmg_2273 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033521.1 2232315 D 416870 CDS YP_001033522.1 125625039 4796651 2232728..2232949 1 NC_009004.1 hypothetical protein 2232949 4796651 llmg_2274 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033522.1 2232728 D 416870 CDS YP_001033523.1 125625040 4796579 complement(2232961..2233320) 1 NC_009004.1 membrane protein; hypothetical protein 2233320 4796579 llmg_2275 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033523.1 2232961 R 416870 CDS YP_001033524.1 125625041 4796746 complement(2233383..2234072) 1 NC_009004.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 2234072 rplA 4796746 rplA Lactococcus lactis subsp. cremoris MG1363 50S ribosomal protein L1 YP_001033524.1 2233383 R 416870 CDS YP_001033525.1 125625042 4798439 complement(2234459..2234884) 1 NC_009004.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 2234884 rplK 4798439 rplK Lactococcus lactis subsp. cremoris MG1363 50S ribosomal protein L11 YP_001033525.1 2234459 R 416870 CDS YP_001033526.1 125625043 4797915 complement(2235020..2235784) 1 NC_009004.1 membrane protein; hypothetical protein 2235784 4797915 llmg_2278 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033526.1 2235020 R 416870 CDS YP_001033527.1 125625044 4798106 complement(2235784..2236662) 1 NC_009004.1 PF00005: ABC transporter; Conserved hypothetical protein; bacitracin transport ATP-binding protein 2236662 bcrA 4798106 bcrA Lactococcus lactis subsp. cremoris MG1363 bacitracin transport ATP-binding protein YP_001033527.1 2235784 R 416870 CDS YP_001033528.1 125625045 4798648 complement(2236729..2236938) 1 NC_009004.1 PF06855: Protein of unknown function DUF1250; hypothetical protein 2236938 4798648 llmg_2280 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033528.1 2236729 R 416870 CDS YP_001033529.1 125625046 4796673 complement(2236972..2237493) 1 NC_009004.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 2237493 pmsR 4796673 pmsR Lactococcus lactis subsp. cremoris MG1363 methionine sulfoxide reductase A YP_001033529.1 2236972 R 416870 CDS YP_001033530.1 125625047 4797834 complement(2237669..2238526) 1 NC_009004.1 IPR008994: Nucleic acid-binding, OB-fold; hypothetical protein 2238526 4797834 llmg_2282 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033530.1 2237669 R 416870 CDS YP_001033531.1 125625048 4796652 complement(2238571..2239029) 1 NC_009004.1 GNAT family acetyltransferase, PF00583: Acetyltransferase (GNAT) family; hypothetical protein 2239029 4796652 llmg_2283 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033531.1 2238571 R 416870 CDS YP_001033532.1 125625049 4796622 complement(2239114..2239671) 1 NC_009004.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 2239671 frr 4796622 frr Lactococcus lactis subsp. cremoris MG1363 ribosome recycling factor YP_001033532.1 2239114 R 416870 CDS YP_001033533.1 125625050 4798942 complement(2239828..2240544) 1 NC_009004.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 2240544 pyrH 4798942 pyrH Lactococcus lactis subsp. cremoris MG1363 uridylate kinase YP_001033533.1 2239828 R 416870 CDS YP_001033534.1 125625051 4797541 complement(2240629..2241081) 1 NC_009004.1 hypothetical protein 2241081 4797541 llmg_2286 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033534.1 2240629 R 416870 CDS YP_001033535.1 125625052 4796749 complement(2241211..2242398) 1 NC_009004.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 2242398 ackA2 4796749 ackA2 Lactococcus lactis subsp. cremoris MG1363 acetate kinase YP_001033535.1 2241211 R 416870 CDS YP_001033536.1 125625053 4798785 complement(2242557..2243744) 1 NC_009004.1 PF00871: Acetokinase, TIGR00016: acetate kinase; High confidence in function and specificity; AckA1 protein 2243744 ackA1 4798785 ackA1 Lactococcus lactis subsp. cremoris MG1363 AckA1 protein YP_001033536.1 2242557 R 416870 CDS YP_001033537.1 125625054 4798772 complement(2243936..2244874) 1 NC_009004.1 IPR000051: SAM (and some other nucleotide) binding motif; hypothetical protein 2244874 4798772 llmg_2290 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033537.1 2243936 R 416870 CDS YP_001033538.1 125625055 4796693 complement(2244962..2245213) 1 NC_009004.1 membrane protein; hypothetical protein 2245213 4796693 llmg_2291 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033538.1 2244962 R 416870 CDS YP_001033539.1 125625056 4796711 complement(2245314..2247155) 1 NC_009004.1 PF00009: Elongation factor Tu GTP binding domain, TIGR01394: GTP-binding protein TypA; Conserved hypothetical protein; GTP-binding protein TypA 2247155 typA 4796711 typA Lactococcus lactis subsp. cremoris MG1363 GTP-binding protein TypA YP_001033539.1 2245314 R 416870 CDS YP_001033540.1 125625057 4798103 complement(2247824..2248228) 1 NC_009004.1 hypothetical protein 2248228 4798103 llmg_2293 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033540.1 2247824 R 416870 CDS YP_001033541.1 125625058 4796571 complement(2248240..2248698) 1 NC_009004.1 membrane protein; hypothetical protein 2248698 4796571 llmg_2294 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033541.1 2248240 R 416870 CDS YP_001033542.1 125625059 4796667 complement(2248713..2249486) 1 NC_009004.1 secreted protein; hypothetical protein 2249486 4796667 llmg_2295 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033542.1 2248713 R 416870 CDS YP_001033543.1 125625060 4797785 complement(2249826..2250554) 1 NC_009004.1 PF04397: LytTr DNA-binding region; hypothetical protein 2250554 4797785 llmg_2297 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033543.1 2249826 R 416870 CDS YP_001033544.1 125625061 4798426 2250747..2250968 1 NC_009004.1 PF06014: Bacterial protein of unknown function (DUF910); hypothetical protein 2250968 4798426 llmg_2298 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033544.1 2250747 D 416870 CDS YP_001033545.1 125625062 4799138 2251002..2251973 1 NC_009004.1 PF00480: ROK family, TIGR00744: ROK family protein ( glucokinase); High confidence in function and specificity; glucokinase 2251973 glk 4799138 glk Lactococcus lactis subsp. cremoris MG1363 glucokinase YP_001033545.1 2251002 D 416870 CDS YP_001033546.1 125625063 4797959 2251976..2252362 1 NC_009004.1 PF00581: Rhodanese-like domain; hypothetical protein 2252362 4797959 llmg_2300 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033546.1 2251976 D 416870 CDS YP_001033547.1 125625064 4796600 2252332..2252436 1 NC_009004.1 hypothetical protein 2252436 4796600 llmg_2301 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033547.1 2252332 D 416870 CDS YP_001033548.1 125625065 4798207 complement(2252478..2252924) 1 NC_009004.1 PF00210: Ferritin-like domain; High confidence in function and specificity; non-heme iron-binding ferritin 2252924 dpsA 4798207 dpsA Lactococcus lactis subsp. cremoris MG1363 non-heme iron-binding ferritin YP_001033548.1 2252478 R 416870 CDS YP_001033549.1 125625066 4798371 2253090..2253755 1 NC_009004.1 PF01478: Peptidase A24A, prepilin type IV, PF06750: Bacterial Peptidase A24 N-terminal domain; High confidence in function and specificity; type 4 prepilin-like protein specific leader peptidase 2253755 comC 4798371 comC Lactococcus lactis subsp. cremoris MG1363 type 4 prepilin-like protein specific leader peptidase YP_001033549.1 2253090 D 416870 CDS YP_001033550.1 125625067 4799035 complement(2253706..2254800) 1 NC_009004.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 2254800 dinP 4799035 dinP Lactococcus lactis subsp. cremoris MG1363 DNA polymerase IV YP_001033550.1 2253706 R 416870 CDS YP_001033551.1 125625068 4798914 complement(2254876..2255367) 1 NC_009004.1 IPR007214: YbaK/prolyl-tRNA synthetase associated region; hypothetical protein 2255367 4798914 llmg_2306 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033551.1 2254876 R 416870 CDS YP_001033552.1 125625069 4798160 complement(2255443..2256936) 1 NC_009004.1 PF00324: Amino acid permease-associated region, TIGR00905: arginine/ornithine antiporter; Conserved hypothetical protein; arginine/ornithine antiporter 2256936 arcD2 4798160 arcD2 Lactococcus lactis subsp. cremoris MG1363 arginine/ornithine antiporter YP_001033552.1 2255443 R 416870 CDS YP_001033553.1 125625070 4796869 complement(2257126..2258256) 1 NC_009004.1 associated with arginine deiminase pathway genes; probably functions in arginine catabolism; transaminase 2258256 arcT 4796869 arcT Lactococcus lactis subsp. cremoris MG1363 transaminase YP_001033553.1 2257126 R 416870 CDS YP_001033554.1 125625071 4796870 complement(2258520..2259464) 1 NC_009004.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 2259464 arcC2 4796870 arcC2 Lactococcus lactis subsp. cremoris MG1363 carbamate kinase YP_001033554.1 2258520 R 416870 CDS YP_001033555.1 125625072 4797220 complement(2259497..2260441) 1 NC_009004.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 2260441 arcC1 4797220 arcC1 Lactococcus lactis subsp. cremoris MG1363 carbamate kinase YP_001033555.1 2259497 R 416870 CDS YP_001033556.1 125625073 4797572 complement(2260459..2262039) 1 NC_009004.1 PF00324:Amino acid permease-associated region, TIGR00905: arginine/ornithine antiporter; High confidence in function and specificity; arginine/ornithine antiporter 2262039 arcD1 4797572 arcD1 Lactococcus lactis subsp. cremoris MG1363 arginine/ornithine antiporter YP_001033556.1 2260459 R 416870 CDS YP_001033557.1 125625074 4796868 complement(2262171..2263235) 1 NC_009004.1 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase 2263235 arcB 4796868 arcB Lactococcus lactis subsp. cremoris MG1363 ornithine carbamoyltransferase YP_001033557.1 2262171 R 416870 CDS YP_001033558.1 125625075 4798543 complement(2263401..2264633) 1 NC_009004.1 catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase 2264633 arcA 4798543 arcA Lactococcus lactis subsp. cremoris MG1363 arginine deiminase YP_001033558.1 2263401 R 416870 CDS YP_001033559.1 125625076 4797819 complement(2264934..2266628) 1 NC_009004.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 2266628 argS 4797819 argS Lactococcus lactis subsp. cremoris MG1363 arginyl-tRNA synthetase YP_001033559.1 2264934 R 416870 CDS YP_001033560.1 125625077 4799140 2266696..2267154 1 NC_009004.1 PF01316: Arginine repressor, PF02863: Arginine repressor, C-terminal domain, TIGR01529: arginine repressor; High confidence in function and specificity; arginine repressor ArgR 2267154 argR 4799140 argR Lactococcus lactis subsp. cremoris MG1363 arginine repressor ArgR YP_001033560.1 2266696 D 416870 CDS YP_001033561.1 125625078 4799142 complement(2267316..2268647) 1 NC_009004.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 2268647 murC 4799142 murC Lactococcus lactis subsp. cremoris MG1363 UDP-N-acetylmuramate--L-alanine ligase YP_001033561.1 2267316 R 416870 CDS YP_001033562.1 125625079 4797414 complement(2268848..2269447) 1 NC_009004.1 hypothetical protein 2269447 4797414 llmg_2318 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033562.1 2268848 R 416870 CDS YP_001033563.1 125625080 4798076 complement(2269664..2272768) 1 NC_009004.1 PF00176:SNF2 family N-terminal domain; Family membership; SWI/SNF family helicase 2272768 snf 4798076 snf Lactococcus lactis subsp. cremoris MG1363 SWI/SNF family helicase YP_001033563.1 2269664 R 416870 CDS YP_001033564.1 125625081 4798445 complement(2272997..2277331) 1 NC_009004.1 hypothetical protein 2277331 4798445 llmg_2320 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033564.1 2272997 R 416870 CDS YP_001033565.1 125625082 4798181 complement(2277746..2279473) 1 NC_009004.1 PF02776: Thiamine pyrophosphate enzyme, N-terminal TPP binding domain, TIGR00118: acetolactate synthase, large subunit, biosynthetic type; High confidence in function and specificity; pyruvate oxidase 2279473 poxL 4798181 poxL Lactococcus lactis subsp. cremoris MG1363 pyruvate oxidase YP_001033565.1 2277746 R 416870 CDS YP_001033566.1 125625083 4797143 complement(2279723..2280679) 1 NC_009004.1 PF00144: Beta-lactamase; hypothetical protein 2280679 4797143 llmg_2322 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033566.1 2279723 R 416870 CDS YP_001033567.1 125625084 4798220 complement(2280752..2281531) 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 2281531 4798220 llmg_2323 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033567.1 2280752 R 416870 CDS YP_001033568.1 125625085 4798218 complement(2281993..2282325) 1 NC_009004.1 hypothetical protein 2282325 4798218 llmg_2324 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033568.1 2281993 R 416870 CDS YP_001033569.1 125625086 4797049 complement(2282357..2282863) 1 NC_009004.1 IPR009002: FMN-binding split barrel; hypothetical protein 2282863 4797049 llmg_2325 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033569.1 2282357 R 416870 CDS YP_001033570.1 125625087 4797134 2283229..2284011 1 NC_009004.1 PF02517: CAAX amino terminal protease , Abortive infection protein; Conserved hypothetical protein; hypothetical protein 2284011 4797134 llmg_2326 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033570.1 2283229 D 416870 CDS YP_001033571.1 125625088 4798088 complement(2284047..2284916) 1 NC_009004.1 PF00230: Major intrinsic protein, TIGR00861: MIP family channel proteins; Family membership; glycerol uptake facilitator protein 2284916 glpF3 4798088 glpF3 Lactococcus lactis subsp. cremoris MG1363 glycerol uptake facilitator protein YP_001033571.1 2284047 R 416870 CDS YP_001033572.1 125625089 4798350 2285088..2287379 1 NC_009004.1 catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue; x-prolyl-dipeptidyl aminopeptidase 2287379 pepXP 4798350 pepXP Lactococcus lactis subsp. cremoris MG1363 x-prolyl-dipeptidyl aminopeptidase YP_001033572.1 2285088 D 416870 CDS YP_001033573.1 125625090 4798728 2287381..2288091 1 NC_009004.1 PF07722: Peptidase C26; hypothetical protein 2288091 4798728 llmg_2329 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033573.1 2287381 D 416870 CDS YP_001033574.1 125625091 4796941 2288241..2289083 1 NC_009004.1 PF00497: Bacterial extracellular solute-binding protein, family 3; Family membership; amino-acid ABC transporter extracellular binding protein 2289083 4796941 llmg_2330 Lactococcus lactis subsp. cremoris MG1363 amino-acid ABC transporter extracellular binding protein YP_001033574.1 2288241 D 416870 CDS YP_001033575.1 125625092 4798296 complement(2289174..2290496) 1 NC_009004.1 PF00070: Pyridine nucleotide-disulphide oxidoreductase, TIGR02053: mercuric reductase; High confidence in function and specificity; pyridine nucleotide-disulfide oxidoreductase 2290496 4798296 llmg_2331 Lactococcus lactis subsp. cremoris MG1363 pyridine nucleotide-disulfide oxidoreductase YP_001033575.1 2289174 R 416870 CDS YP_001033576.1 125625093 4798062 complement(2290608..2292059) 1 NC_009004.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 2292059 gltX 4798062 gltX Lactococcus lactis subsp. cremoris MG1363 glutamyl-tRNA synthetase YP_001033576.1 2290608 R 416870 CDS YP_001033577.1 125625094 4798637 complement(2292686..2293228) 1 NC_009004.1 PF00857: Isochorismatase hydrolase, Hypothetical isochorismatase; Family membership; hypothetical protein 2293228 4798637 llmg_2333 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033577.1 2292686 R 416870 CDS YP_001033578.1 125625095 4798949 2293373..2294224 1 NC_009004.1 PF00126: Bacterial regulatory helix-turn-helix protein, lysR family; Conserved hypothetical protein; ORF3; hypothetical protein 2294224 4798949 llmg_2334 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033578.1 2293373 D 416870 CDS YP_001033579.1 125625096 4798952 complement(2294257..2295180) 1 NC_009004.1 PF01569: PAP2 superfamily, membrane- associated phospholipid phosphatase; Conserved hypothetical protein; hypothetical protein 2295180 4798952 llmg_2335 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033579.1 2294257 R 416870 CDS YP_001033580.1 125625097 4798955 2295320..2295871 1 NC_009004.1 PF00583: Acetyltransferase (GNAT) family; Conserved hypothetical protein; acetyltransferase 2295871 4798955 llmg_2336 Lactococcus lactis subsp. cremoris MG1363 acetyltransferase YP_001033580.1 2295320 D 416870 CDS YP_001033581.1 125625098 4798956 complement(2295962..2296285) 1 NC_009004.1 PF06304: Protein of unknown function (DUF1048); hypothetical protein 2296285 4798956 llmg_2337 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033581.1 2295962 R 416870 CDS YP_001033582.1 125625099 4797341 complement(2296282..2296620) 1 NC_009004.1 PF06304: Protein of unknown function (DUF1048); hypothetical protein 2296620 4797341 llmg_2338 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033582.1 2296282 R 416870 CDS YP_001033583.1 125625100 4797325 complement(2296613..2296969) 1 NC_009004.1 PF03551: Transcriptional regulator PadR-like family; Family membership; transcriptional regulator 2296969 4797325 llmg_2339 Lactococcus lactis subsp. cremoris MG1363 transcriptional regulator YP_001033583.1 2296613 R 416870 CDS YP_001033584.1 125625101 4797350 complement(2297090..2297719) 1 NC_009004.1 IPR009002: FMN-binding split barrel; hypothetical protein 2297719 4797350 llmg_2340 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033584.1 2297090 R 416870 CDS YP_001033585.1 125625102 4797305 complement(2297778..2298863) 1 NC_009004.1 hypothetical protein 2298863 4797305 llmg_2341 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033585.1 2297778 R 416870 CDS YP_001033586.1 125625103 4797939 2299130..2299807 1 NC_009004.1 PF06912: Protein of unknown function DUF1275; Conserved hypothetical protein; hypothetical protein 2299807 4797939 llmg_2342 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033586.1 2299130 D 416870 CDS YP_001033587.1 125625104 4797910 complement(2299853..2301214) 1 NC_009004.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 2301214 radA 4797910 radA Lactococcus lactis subsp. cremoris MG1363 DNA repair protein RadA YP_001033587.1 2299853 R 416870 CDS YP_001033588.1 125625105 4798009 complement(2301833..2302396) 1 NC_009004.1 PF00535: Glycosyl transferase, family 2; Family membership; glycosyl transferase family protein 2302396 4798009 llmg_2344 Lactococcus lactis subsp. cremoris MG1363 glycosyl transferase family protein YP_001033588.1 2301833 R 416870 CDS YP_001033589.1 125625106 4797956 complement(2302378..2302923) 1 NC_009004.1 TIGR01656 : histidinol-phosphate phosphatase domain, hisB like protein; High confidence in function and specificity; histidinol-phosphate phosphatase 2302923 4797956 llmg_2345 Lactococcus lactis subsp. cremoris MG1363 histidinol-phosphate phosphatase YP_001033589.1 2302378 R 416870 CDS YP_001033590.1 125625107 4797273 complement(2302920..2303495) 1 NC_009004.1 PF01380: Sugar isomerase (SIS domain), TIGR00441: phosphoheptose isomerase; High confidence in function and specificity; GmhA protein 2303495 gmhA 4797273 gmhA Lactococcus lactis subsp. cremoris MG1363 GmhA protein YP_001033590.1 2302920 R 416870 CDS YP_001033591.1 125625108 4798756 complement(2303557..2304531) 1 NC_009004.1 PF00288: GHMP kinases ATP-binding protein; Family membership; hypothetical protein 2304531 4798756 llmg_2347 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033591.1 2303557 R 416870 CDS YP_001033592.1 125625109 4797314 complement(2304561..2306084) 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 2306084 4797314 llmg_2348 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033592.1 2304561 R 416870 CDS YP_001033593.1 125625110 4797250 complement(2306158..2307081) 1 NC_009004.1 PF01531: Glycosyl transferase, family 11; Family membership; glycosyl transferase family protein 2307081 4797250 llmg_2349 Lactococcus lactis subsp. cremoris MG1363 glycosyl transferase family protein YP_001033593.1 2306158 R 416870 CDS YP_001033594.1 125625111 4798646 complement(2307078..2308037) 1 NC_009004.1 PF00535: Glycosyl transferase, family 2; Family membership; glycosyl transferase family protein 2308037 4798646 llmg_2350 Lactococcus lactis subsp. cremoris MG1363 glycosyl transferase family protein YP_001033594.1 2307078 R 416870 CDS YP_001033595.1 125625112 4799024 complement(2308056..2309036) 1 NC_009004.1 PF00535: Glycosyl transferase, family 2; Family membership; glycosyl transferase family protein 2309036 4799024 llmg_2351 Lactococcus lactis subsp. cremoris MG1363 glycosyl transferase family protein YP_001033595.1 2308056 R 416870 CDS YP_001033596.1 125625113 4798516 complement(2309043..2310233) 1 NC_009004.1 PF02388: FemAB family, considered as a factor influencing the level of methicillin resistance in Staphylococcus aureus; Conserved hypothetical protein; peptidoglycan branched peptide synthesis protein 2310233 murM 4798516 murM Lactococcus lactis subsp. cremoris MG1363 peptidoglycan branched peptide synthesis protein YP_001033596.1 2309043 R 416870 CDS YP_001033597.1 125625114 4797004 complement(2310945..2311325) 1 NC_009004.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 2311325 rplQ 4797004 rplQ Lactococcus lactis subsp. cremoris MG1363 50S ribosomal protein L17 YP_001033597.1 2310945 R 416870 CDS YP_001033598.1 125625115 4797865 complement(2311344..2312282) 1 NC_009004.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 2312282 rpoA 4797865 rpoA Lactococcus lactis subsp. cremoris MG1363 DNA-directed RNA polymerase subunit alpha YP_001033598.1 2311344 R 416870 CDS YP_001033599.1 125625116 4798819 complement(2312331..2312714) 1 NC_009004.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 2312714 rpsK 4798819 rpsK Lactococcus lactis subsp. cremoris MG1363 30S ribosomal protein S11 YP_001033599.1 2312331 R 416870 CDS YP_001033600.1 125625117 4798259 complement(2312735..2313100) 1 NC_009004.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 2313100 rpsM 4798259 rpsM Lactococcus lactis subsp. cremoris MG1363 30S ribosomal protein S13 YP_001033600.1 2312735 R 416870 CDS YP_001033601.1 125625118 4797226 complement(2313118..2313234) 1 NC_009004.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 2313234 rpmJ 4797226 rpmJ Lactococcus lactis subsp. cremoris MG1363 50S ribosomal protein L36 YP_001033601.1 2313118 R 416870 CDS YP_001033602.1 125625119 4798815 complement(2313288..2313506) 1 NC_009004.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 2313506 infA 4798815 infA Lactococcus lactis subsp. cremoris MG1363 translation initiation factor IF-1 YP_001033602.1 2313288 R 416870 CDS YP_001033603.1 125625120 4797666 complement(2313809..2314456) 1 NC_009004.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 2314456 adk 4797666 adk Lactococcus lactis subsp. cremoris MG1363 adenylate kinase YP_001033603.1 2313809 R 416870 CDS YP_001033604.1 125625121 4797668 complement(2314596..2315915) 1 NC_009004.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 2315915 secY 4797668 secY Lactococcus lactis subsp. cremoris MG1363 preprotein translocase subunit SecY YP_001033604.1 2314596 R 416870 CDS YP_001033605.1 125625122 4797213 complement(2315993..2316436) 1 NC_009004.1 late assembly protein; 50S ribosomal protein L15 2316436 rplO 4797213 rplO Lactococcus lactis subsp. cremoris MG1363 50S ribosomal protein L15 YP_001033605.1 2315993 R 416870 CDS YP_001033606.1 125625123 4797873 complement(2316732..2316911) 1 NC_009004.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 2316911 rpmD 4797873 rpmD Lactococcus lactis subsp. cremoris MG1363 50S ribosomal protein L30 YP_001033606.1 2316732 R 416870 CDS YP_001033607.1 125625124 4798090 complement(2316922..2317428) 1 NC_009004.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 2317428 rpsE 4798090 rpsE Lactococcus lactis subsp. cremoris MG1363 30S ribosomal protein S5 YP_001033607.1 2316922 R 416870 CDS YP_001033608.1 125625125 4799022 complement(2317447..2317794) 1 NC_009004.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 2317794 rplR 4799022 rplR Lactococcus lactis subsp. cremoris MG1363 50S ribosomal protein L18 YP_001033608.1 2317447 R 416870 CDS YP_001033609.1 125625126 4797863 complement(2318063..2318599) 1 NC_009004.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 2318599 rplF 4797863 rplF Lactococcus lactis subsp. cremoris MG1363 50S ribosomal protein L6 YP_001033609.1 2318063 R 416870 CDS YP_001033610.1 125625127 4797933 complement(2318816..2319214) 1 NC_009004.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 2319214 rpsH 4797933 rpsH Lactococcus lactis subsp. cremoris MG1363 30S ribosomal protein S8 YP_001033610.1 2318816 R 416870 CDS YP_001033611.1 125625128 4798934 complement(2319420..2319680) 1 NC_009004.1 hypothetical protein 2319680 4798934 llmg_2368 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033611.1 2319420 R 416870 CDS YP_001033612.1 125625129 4798005 complement(2319744..2320025) 1 NC_009004.1 hypothetical protein 2320025 4798005 llmg_2369 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033612.1 2319744 R 416870 CDS YP_001033613.1 125625130 4798055 complement(2320176..2320361) 1 NC_009004.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 2320361 rpsN 4798055 rpsN Lactococcus lactis subsp. cremoris MG1363 30S ribosomal protein S14 YP_001033613.1 2320176 R 416870 CDS YP_001033614.1 125625131 4797215 complement(2320380..2320922) 1 NC_009004.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 2320922 rplE 4797215 rplE Lactococcus lactis subsp. cremoris MG1363 50S ribosomal protein L5 YP_001033614.1 2320380 R 416870 CDS YP_001033615.1 125625132 4797891 complement(2320942..2321247) 1 NC_009004.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 2321247 rplX 4797891 rplX Lactococcus lactis subsp. cremoris MG1363 50S ribosomal protein L24 YP_001033615.1 2320942 R 416870 CDS YP_001033616.1 125625133 4799034 complement(2321381..2321749) 1 NC_009004.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 2321749 rplN 4799034 rplN Lactococcus lactis subsp. cremoris MG1363 50S ribosomal protein L14 YP_001033616.1 2321381 R 416870 CDS YP_001033617.1 125625134 4798014 complement(2321772..2322032) 1 NC_009004.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 2322032 rpsQ 4798014 rpsQ Lactococcus lactis subsp. cremoris MG1363 30S ribosomal protein S17 YP_001033617.1 2321772 R 416870 CDS YP_001033618.1 125625135 4797789 complement(2322053..2322262) 1 NC_009004.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 2322262 rpmC 4797789 rpmC Lactococcus lactis subsp. cremoris MG1363 50S ribosomal protein L29 YP_001033618.1 2322053 R 416870 CDS YP_001033619.1 125625136 4798472 complement(2322262..2322675) 1 NC_009004.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 2322675 rplP 4798472 rplP Lactococcus lactis subsp. cremoris MG1363 50S ribosomal protein L16 YP_001033619.1 2322262 R 416870 CDS YP_001033620.1 125625137 4797871 complement(2322679..2323332) 1 NC_009004.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 2323332 rpsC 4797871 rpsC Lactococcus lactis subsp. cremoris MG1363 30S ribosomal protein S3 YP_001033620.1 2322679 R 416870 CDS YP_001033621.1 125625138 4798792 complement(2323345..2323692) 1 NC_009004.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 2323692 rplV 4798792 rplV Lactococcus lactis subsp. cremoris MG1363 50S ribosomal protein L22 YP_001033621.1 2323345 R 416870 CDS YP_001033622.1 125625139 4797839 complement(2323708..2323986) 1 NC_009004.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 2323986 rpsS 4797839 rpsS Lactococcus lactis subsp. cremoris MG1363 30S ribosomal protein S19 YP_001033622.1 2323708 R 416870 CDS YP_001033623.1 125625140 4798645 complement(2324146..2324976) 1 NC_009004.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 2324976 rplB 4798645 rplB Lactococcus lactis subsp. cremoris MG1363 50S ribosomal protein L2 YP_001033623.1 2324146 R 416870 CDS YP_001033624.1 125625141 4798431 complement(2324992..2325285) 1 NC_009004.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 2325285 rplW 4798431 rplW Lactococcus lactis subsp. cremoris MG1363 50S ribosomal protein L23 YP_001033624.1 2324992 R 416870 CDS YP_001033625.1 125625142 4798524 complement(2325285..2325911) 1 NC_009004.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 2325911 rplD 4798524 rplD Lactococcus lactis subsp. cremoris MG1363 50S ribosomal protein L4 YP_001033625.1 2325285 R 416870 CDS YP_001033626.1 125625143 4798418 complement(2325937..2326560) 1 NC_009004.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 2326560 rplC 4798418 rplC Lactococcus lactis subsp. cremoris MG1363 50S ribosomal protein L3 YP_001033626.1 2325937 R 416870 CDS YP_001033627.1 125625144 4798419 complement(2326579..2326887) 1 NC_009004.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 2326887 rpsJ 4798419 rpsJ Lactococcus lactis subsp. cremoris MG1363 30S ribosomal protein S10 YP_001033627.1 2326579 R 416870 CDS YP_001033628.1 125625145 4798275 2327222..2327587 1 NC_009004.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 2327587 mscL 4798275 mscL Lactococcus lactis subsp. cremoris MG1363 large-conductance mechanosensitive channel YP_001033628.1 2327222 D 416870 CDS YP_001033629.1 125625146 4796805 complement(2327625..2328914) 1 NC_009004.1 multidrug resistance protein, PF01554: MatE, TIGR00797MATE efflux family protein; hypothetical protein 2328914 4796805 llmg_2386 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033629.1 2327625 R 416870 CDS YP_001033630.1 125625147 4798502 complement(2328911..2330401) 1 NC_009004.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 2330401 thrC 4798502 thrC Lactococcus lactis subsp. cremoris MG1363 threonine synthase YP_001033630.1 2328911 R 416870 CDS YP_001033631.1 125625148 4796940 complement(2330500..2331057) 1 NC_009004.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 2331057 nusG 4796940 nusG Lactococcus lactis subsp. cremoris MG1363 transcription antitermination protein NusG YP_001033631.1 2330500 R 416870 CDS YP_001033632.1 125625149 4798605 complement(2331263..2331457) 1 NC_009004.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 2331457 secE 4798605 secE Lactococcus lactis subsp. cremoris MG1363 preprotein translocase subunit SecE YP_001033632.1 2331263 R 416870 CDS YP_001033633.1 125625150 4797237 complement(2331569..2331718) 1 NC_009004.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif; 50S ribosomal protein L33 2331718 rpmG 4797237 rpmG Lactococcus lactis subsp. cremoris MG1363 50S ribosomal protein L33 YP_001033633.1 2331569 R 416870 CDS YP_001033634.1 125625151 4798801 complement(2331759..2333576) 1 NC_009004.1 acyltransferase, PF01757: Acyltransferase; Conserved hypothetical protein; hypothetical protein 2333576 4798801 llmg_2391 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033634.1 2331759 R 416870 CDS YP_001033635.1 125625152 4798109 complement(2333678..2335909) 1 NC_009004.1 PF00912: Transglycosylase; High confidence in function and specificity; penicillin-binding protein 2a 2335909 pbp2A 4798109 pbp2A Lactococcus lactis subsp. cremoris MG1363 penicillin-binding protein 2a YP_001033635.1 2333678 R 416870 CDS YP_001033636.1 125625153 4798553 complement(2336296..2336931) 1 NC_009004.1 PF04239: Protein of unknown function DUF421; hypothetical protein 2336931 4798553 llmg_2393 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033636.1 2336296 R 416870 CDS YP_001033637.1 125625154 4798081 complement(2336949..2337380) 1 NC_009004.1 hypothetical protein 2337380 4798081 llmg_2394 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033637.1 2336949 R 416870 CDS YP_001033638.1 125625155 4796847 complement(2337495..2337911) 1 NC_009004.1 FMN-binding protein, IPR009002: FMN- binding split barrel; hypothetical protein 2337911 4796847 llmg_2395 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033638.1 2337495 R 416870 CDS YP_001033639.1 125625156 4796857 2338067..2338939 1 NC_009004.1 PF00849: RNA pseudouridylate synthase , TIGR00005: ribosomal large subunit pseudouridine synthases, RluD subfamily; High confidence in function and specificity; ribosomal large subunit pseudouridine synthase 2338939 rluA 4796857 rluA Lactococcus lactis subsp. cremoris MG1363 ribosomal large subunit pseudouridine synthase YP_001033639.1 2338067 D 416870 CDS YP_001033640.1 125625157 4799038 complement(2340471..2341280) 1 NC_009004.1 PF00950: ABC-3 transport family; High confidence in function and specificity; zinc ABC transporter permease 2341280 zitP 4799038 zitP Lactococcus lactis subsp. cremoris MG1363 zinc ABC transporter permease YP_001033640.1 2340471 R 416870 CDS YP_001033641.1 125625158 4797161 complement(2341273..2342010) 1 NC_009004.1 PF00005: ABC transporter; High confidence in function and specificity; zinc ABC transporter ATP binding protein 2342010 zitQ 4797161 zitQ Lactococcus lactis subsp. cremoris MG1363 zinc ABC transporter ATP binding protein YP_001033641.1 2341273 R 416870 CDS YP_001033642.1 125625159 4797162 complement(2342189..2343031) 1 NC_009004.1 PF01297.7: Periplasmic solute binding protein family; High confidence in function and specificity; zinc ABC transporter substrate binding protein 2343031 zitS 4797162 zitS Lactococcus lactis subsp. cremoris MG1363 zinc ABC transporter substrate binding protein YP_001033642.1 2342189 R 416870 CDS YP_001033643.1 125625160 4799067 complement(2343028..2343465) 1 NC_009004.1 PF01047.9: Bacterial regulatory protein, MarR; High confidence in function and specificity; transcriptional regulator of the zit operon 2343465 zitR 4799067 zitR Lactococcus lactis subsp. cremoris MG1363 transcriptional regulator of the zit operon YP_001033643.1 2343028 R 416870 CDS YP_001033644.1 125625161 4798053 complement(2343546..2343845) 1 NC_009004.1 hypothetical protein 2343845 4798053 llmg_2402 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033644.1 2343546 R 416870 CDS YP_001033645.1 125625162 4797498 complement(2343869..2344315) 1 NC_009004.1 hypothetical protein 2344315 4797498 llmg_2403 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033645.1 2343869 R 416870 CDS YP_001033646.1 125625163 4797503 complement(2344278..2344664) 1 NC_009004.1 hypothetical protein 2344664 4797503 llmg_2404 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033646.1 2344278 R 416870 CDS YP_001033647.1 125625164 4797507 complement(2344546..2344989) 1 NC_009004.1 High confidence in function and specificity; competence protein ComGD 2344989 comGD 4797507 comGD Lactococcus lactis subsp. cremoris MG1363 competence protein ComGD YP_001033647.1 2344546 R 416870 CDS YP_001033648.1 125625165 4798798 complement(2344937..2345314) 1 NC_009004.1 Specificity unclear; competence protein ComGC 2345314 comGC 4798798 comGC Lactococcus lactis subsp. cremoris MG1363 competence protein ComGC YP_001033648.1 2344937 R 416870 CDS YP_001033649.1 125625166 4798796 complement(2345332..2346420) 1 NC_009004.1 PF00482: Bacterial type II secretion system protein F domain, membrane protein; Conserved hypothetical protein; competence protein ComGB 2346420 comGB 4798796 comGB Lactococcus lactis subsp. cremoris MG1363 competence protein ComGB YP_001033649.1 2345332 R 416870 CDS YP_001033650.1 125625167 4798794 complement(2346257..2347237) 1 NC_009004.1 PF00437: Type II/IV secretion system protein; Conserved hypothetical protein; competence protein ComGA 2347237 comGA 4798794 comGA Lactococcus lactis subsp. cremoris MG1363 competence protein ComGA YP_001033650.1 2346257 R 416870 CDS YP_001033651.1 125625168 4798790 complement(2347351..2352258) 1 NC_009004.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity; DNA polymerase III PolC 2352258 polC 4798790 polC Lactococcus lactis subsp. cremoris MG1363 DNA polymerase III PolC YP_001033651.1 2347351 R 416870 CDS YP_001033652.1 125625169 4797074 complement(2352432..2352968) 1 NC_009004.1 hypothetical protein 2352968 4797074 llmg_2410 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033652.1 2352432 R 416870 CDS YP_001033653.1 125625170 4796999 complement(2354322..2356172) 1 NC_009004.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 2356172 proS 4796999 proS Lactococcus lactis subsp. cremoris MG1363 prolyl-tRNA synthetase YP_001033653.1 2354322 R 416870 CDS YP_001033654.1 125625171 4797040 complement(2356242..2357528) 1 NC_009004.1 PF02163: Peptidase M50, TIGR00054: membrane- associated zinc metalloprotease, High confidence in function and specificity; zinc metalloprotease 2357528 4797040 llmg_2413 Lactococcus lactis subsp. cremoris MG1363 zinc metalloprotease YP_001033654.1 2356242 R 416870 CDS YP_001033655.1 125625172 4797516 complement(2357547..2358350) 1 NC_009004.1 PF01148.9: Phosphatidate cytidylyltransferase, PF01148: Cytidylyltransferase; High confidence in function and specificity; phosphatidate cytidylyltransferase 2358350 cdsA 4797516 cdsA Lactococcus lactis subsp. cremoris MG1363 phosphatidate cytidylyltransferase YP_001033655.1 2357547 R 416870 CDS YP_001033656.1 125625173 4798290 complement(2358350..2359084) 1 NC_009004.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 2359084 uppS 4798290 uppS Lactococcus lactis subsp. cremoris MG1363 undecaprenyl pyrophosphate synthase YP_001033656.1 2358350 R 416870 CDS YP_001033657.1 125625174 4797262 complement(2359435..2359767) 1 NC_009004.1 PF02699: Preprotein translocase subunit, TIGR00739: preprotein translocase, YajC subunit; hypothetical protein 2359767 yajC 4797262 yajC Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033657.1 2359435 R 416870 CDS YP_001033658.1 125625175 4798925 complement(2359862..2360560) 1 NC_009004.1 hypothetical protein 2360560 4798925 llmg_2417 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033658.1 2359862 R 416870 CDS YP_001033659.1 125625176 4798521 complement(2360578..2361057) 1 NC_009004.1 SPOUT methyltransferase; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 2361057 4798521 llmg_2418 Lactococcus lactis subsp. cremoris MG1363 rRNA large subunit methyltransferase YP_001033659.1 2360578 R 416870 CDS YP_001033660.1 125625177 4797497 2361433..2362656 1 NC_009004.1 serine protease, PF00089: Trypsin, TIGR02037: degP_htrA_DO (protease DO); High confidence in function and specificity; housekeeping protease 2362656 htrA 4797497 htrA Lactococcus lactis subsp. cremoris MG1363 housekeeping protease YP_001033660.1 2361433 D 416870 CDS YP_001033661.1 125625178 4797677 2362776..2363774 1 NC_009004.1 PF00534: Glycosyl transferasegroup 1; hypothetical protein 2363774 4797677 llmg_2420 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033661.1 2362776 D 416870 CDS YP_001033662.1 125625179 4797505 2363920..2365260 1 NC_009004.1 PF00534: Glycosyl transferases group 1; hypothetical protein 2365260 4797505 llmg_2421 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033662.1 2363920 D 416870 CDS YP_001033663.1 125625180 4797519 2365368..2365592 1 NC_009004.1 hypothetical protein 2365592 4797519 llmg_2422 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033663.1 2365368 D 416870 CDS YP_001033664.1 125625181 4797921 2365736..2366740 1 NC_009004.1 hypothetical protein 2366740 4797921 llmg_2423 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033664.1 2365736 D 416870 CDS YP_001033665.1 125625182 4798941 complement(2366797..2367549) 1 NC_009004.1 PF01367: SAM (and some other nucleotide) binding motif; hypothetical protein 2367549 4798941 llmg_2424 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033665.1 2366797 R 416870 CDS YP_001033666.1 125625183 4797780 complement(2367757..2370390) 1 NC_009004.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 2370390 polA 4797780 polA Lactococcus lactis subsp. cremoris MG1363 DNA polymerase I YP_001033666.1 2367757 R 416870 CDS YP_001033667.1 125625184 4799048 2370652..2371407 1 NC_009004.1 TIGR00099: Cof-like hydrolase; hypothetical protein 2371407 4799048 llmg_2426 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033667.1 2370652 D 416870 CDS YP_001033668.1 125625185 4797447 complement(2376782..2377273) 1 NC_009004.1 Sigma factor, regulation of competence; competence regulator ComX 2377273 comX 4797447 comX Lactococcus lactis subsp. cremoris MG1363 competence regulator ComX YP_001033668.1 2376782 R 416870 CDS YP_001033669.1 125625186 4798799 complement(2377538..2379268) 1 NC_009004.1 acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation; septation ring formation regulator EzrA 2379268 ezrA 4798799 ezrA Lactococcus lactis subsp. cremoris MG1363 septation ring formation regulator EzrA YP_001033669.1 2377538 R 416870 CDS YP_001033670.1 125625187 4797460 complement(2379473..2380501) 1 NC_009004.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 2380501 tsf 4797460 tsf Lactococcus lactis subsp. cremoris MG1363 elongation factor Ts YP_001033670.1 2379473 R 416870 CDS YP_001033671.1 125625188 4797347 complement(2380623..2381390) 1 NC_009004.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 2381390 rpsB 4797347 rpsB Lactococcus lactis subsp. cremoris MG1363 30S ribosomal protein S2 YP_001033671.1 2380623 R 416870 CDS YP_001033672.1 125625189 4798780 2381785..2382810 1 NC_009004.1 hypothetical protein 2382810 4798780 llmg_2431 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033672.1 2381785 D 416870 CDS YP_001033673.1 125625190 4798121 2383065..2385776 1 NC_009004.1 PF00465.7: Iron-containing alcohol dehydrogenase; High confidence in function and specificity; bifunctional acetaldehyde-CoA/alcohol dehydrogenase 2385776 adhE 4798121 adhE Lactococcus lactis subsp. cremoris MG1363 bifunctional acetaldehyde-CoA/alcohol dehydrogenase YP_001033673.1 2383065 D 416870 CDS YP_001033674.1 125625191 4797633 complement(2386051..2386158) 1 NC_009004.1 hypothetical protein 2386158 4797633 llmg_2433 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033674.1 2386051 R 416870 CDS YP_001033675.1 125625192 4797520 complement(2386240..2386737) 1 NC_009004.1 hypothetical protein 2386737 4797520 llmg_2434 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033675.1 2386240 R 416870 CDS YP_001033676.1 125625193 4798541 complement(2386724..2386933) 1 NC_009004.1 Region start changed from 2386948 to 2386933 (-15 bases); hypothetical protein 2386933 4798541 llmg_2435 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033676.1 2386724 R 416870 CDS YP_001033677.1 125625194 4798763 complement(2386930..2387757) 1 NC_009004.1 PF04055: Radical SAM superfamily; Family membership; hypothetical protein 2387757 4798763 llmg_2436 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033677.1 2386930 R 416870 CDS YP_001033678.1 125625195 4796770 complement(2389975..2390832) 1 NC_009004.1 TIGR01716: Transcriptional activator Rgg/GadR/MutR, C-terminal domain, IPR010057: Transcriptional activator Rgg/GadR/MutR, C-terminal; Conserved hypothetical protein; HTH-type transcriptional regulator 2390832 4796770 llmg_2438 Lactococcus lactis subsp. cremoris MG1363 HTH-type transcriptional regulator YP_001033678.1 2389975 R 416870 CDS YP_001033679.1 125625196 4798327 complement(2390884..2392020) 1 NC_009004.1 PF07690: Major facilitator superfamily MFS_1; hypothetical protein 2392020 4798327 llmg_2439 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033679.1 2390884 R 416870 CDS YP_001033680.1 125625197 4797435 complement(2392017..2393336) 1 NC_009004.1 Coenzyme PQQ synthesis protein E , PF04055: Radical SAM superfamily, IPR006638 Elongator protein 3/MiaB/NifB; High confidence in function and specificity; hypothetical protein 2393336 4797435 llmg_2440 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033680.1 2392017 R 416870 CDS YP_001033681.1 125625198 4798776 complement(2393404..2393517) 1 NC_009004.1 hypothetical protein 2393517 4798776 llmg_2441 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033681.1 2393404 R 416870 CDS YP_001033682.1 125625199 4797730 complement(2393837..2394868) 1 NC_009004.1 Conserved hypothetical protein; hypothetical protein 2394868 4797730 llmg_2442 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033682.1 2393837 R 416870 CDS YP_001033683.1 125625200 4798324 complement(2394852..2395352) 1 NC_009004.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 2395352 coaD 4798324 coaD Lactococcus lactis subsp. cremoris MG1363 phosphopantetheine adenylyltransferase YP_001033683.1 2394852 R 416870 CDS YP_001033684.1 125625201 4796696 complement(2395400..2395939) 1 NC_009004.1 PF03602:Conserved hypothetical protein 95, TIGR00095: methyltransferase; hypothetical protein 2395939 4796696 llmg_2444 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033684.1 2395400 R 416870 CDS YP_001033685.1 125625202 4798080 complement(2396112..2397329) 1 NC_009004.1 PF07690: Major facilitator superfamilyI, TIGR00880: Multidrug resistance protein; Conserved hypothetical protein; multidrug resistance protein 2397329 4798080 llmg_2445 Lactococcus lactis subsp. cremoris MG1363 multidrug resistance protein YP_001033685.1 2396112 R 416870 CDS YP_001033686.1 125625203 4797726 complement(2397414..2398640) 1 NC_009004.1 PF07690: Major facilitator superfamily I, TIGR00880: Multidrug resistance protein; High confidence in function and specificity; multidrug resistance protein 2398640 lmrP 4797726 lmrP Lactococcus lactis subsp. cremoris MG1363 multidrug resistance protein YP_001033686.1 2397414 R 416870 CDS YP_001033687.1 125625204 4798622 2399342..2400448 1 NC_009004.1 hypothetical protein 2400448 4798622 llmg_2447 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033687.1 2399342 D 416870 CDS YP_001033688.1 125625205 4797611 complement(2400544..2401890) 1 NC_009004.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 2401890 pgi 4797611 pgi Lactococcus lactis subsp. cremoris MG1363 glucose-6-phosphate isomerase YP_001033688.1 2400544 R 416870 CDS YP_001033689.1 125625206 4798372 2402210..2402740 1 NC_009004.1 PF03692.4: Protein of unknown function UPF0153; hypothetical protein 2402740 4798372 llmg_2449 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033689.1 2402210 D 416870 CDS YP_001033690.1 125625207 4797615 complement(2402774..2403514) 1 NC_009004.1 alcohol dehydrogenase; hypothetical protein 2403514 4797615 llmg_2450 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033690.1 2402774 R 416870 CDS YP_001033691.1 125625208 4797624 complement(2403560..2404363) 1 NC_009004.1 transcriptional regulator, IPR010982: Lambda repressor-like, DNA-binding; hypothetical protein 2404363 4797624 llmg_2451 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033691.1 2403560 R 416870 CDS YP_001033692.1 125625209 4797628 complement(2404433..2405278) 1 NC_009004.1 hypothetical protein 2405278 4797628 llmg_2452 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033692.1 2404433 R 416870 CDS YP_001033693.1 125625210 4797635 2405452..2405784 1 NC_009004.1 PF01638: Protein of unknown function DUF24, predicted transcriptional regulator; Conserved hypothetical protein; transcriptional regulator 2405784 4797635 llmg_2453 Lactococcus lactis subsp. cremoris MG1363 transcriptional regulator YP_001033693.1 2405452 D 416870 CDS YP_001033694.1 125625211 4797644 2405901..2406230 1 NC_009004.1 hypothetical protein 2406230 4797644 llmg_2454 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033694.1 2405901 D 416870 CDS YP_001033695.1 125625212 4797649 complement(2406273..2408915) 1 NC_009004.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 2408915 valS 4797649 valS Lactococcus lactis subsp. cremoris MG1363 valyl-tRNA synthetase YP_001033695.1 2406273 R 416870 CDS YP_001033696.1 125625213 4798436 complement(2408951..2409439) 1 NC_009004.1 hypothetical protein 2409439 4798436 llmg_2456 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033696.1 2408951 R 416870 CDS YP_001033697.1 125625214 4797655 complement(2409436..2409555) 1 NC_009004.1 hypothetical protein 2409555 4797655 llmg_2457 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033697.1 2409436 R 416870 CDS YP_001033698.1 125625215 4797661 complement(2409746..2410402) 1 NC_009004.1 PF07299: Fibronectin-binding protein (FBP); fibronectin-binding protein 2410402 4797661 llmg_2458 Lactococcus lactis subsp. cremoris MG1363 fibronectin-binding protein YP_001033698.1 2409746 R 416870 CDS YP_001033699.1 125625216 4797667 complement(2410880..2411128) 1 NC_009004.1 hypothetical protein 2411128 4797667 llmg_2459 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033699.1 2410880 R 416870 CDS YP_001033700.1 125625217 4797672 complement(2411201..2411545) 1 NC_009004.1 PF02575: Protein of unknown function DUF419; hypothetical protein 2411545 4797672 llmg_2460 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033700.1 2411201 R 416870 CDS YP_001033701.1 125625218 4797679 complement(2411538..2412059) 1 NC_009004.1 hypothetical protein 2412059 4797679 llmg_2461 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033701.1 2411538 R 416870 CDS YP_001033702.1 125625219 4797684 complement(2412260..2412979) 1 NC_009004.1 PF03483: B3/4 domain; hypothetical protein 2412979 4797684 llmg_2463 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033702.1 2412260 R 416870 CDS YP_001033703.1 125625220 4797691 complement(2413060..2414601) 1 NC_009004.1 PF01938: TRAM domain, TIGR00479: 23S rRNA (uracil-5- )-methyltransferase RumA; Conserved hypothetical protein; RNA methyltransferase 2414601 4797691 llmg_2464 Lactococcus lactis subsp. cremoris MG1363 RNA methyltransferase YP_001033703.1 2413060 R 416870 CDS YP_001033704.1 125625221 4797701 complement(2414829..2417606) 1 NC_009004.1 PF06458: MucBP domain; hypothetical protein 2417606 4797701 llmg_2465 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033704.1 2414829 R 416870 CDS YP_001033705.1 125625222 4797707 2417964..2418773 1 NC_009004.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 2418773 recX 4797707 recX Lactococcus lactis subsp. cremoris MG1363 recombination regulator RecX YP_001033705.1 2417964 D 416870 CDS YP_001033706.1 125625223 4798480 complement(2424123..2425538) 1 NC_009004.1 PF02447: GntP family permease, TIGR00791: gluconate transporter; High confidence in function and specificity; gluconate transport protein 2425538 gntP 4798480 gntP Lactococcus lactis subsp. cremoris MG1363 gluconate transport protein YP_001033706.1 2424123 R 416870 CDS YP_001033707.1 125625224 4798483 complement(2425675..2427183) 1 NC_009004.1 PF00370: FGGY family of carbohydrate kinases, N- terminal domain, TIGR01314: gntK_FGGY: gluconate kinase; High confidence in function and specificity; gluconate kinase 2427183 gntK 4798483 gntK Lactococcus lactis subsp. cremoris MG1363 gluconate kinase YP_001033707.1 2425675 R 416870 CDS YP_001033708.1 125625225 4797450 complement(2427450..2428355) 1 NC_009004.1 similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate; 6-phosphogluconate dehydrogenase 2428355 gntZ 4797450 gntZ Lactococcus lactis subsp. cremoris MG1363 6-phosphogluconate dehydrogenase YP_001033708.1 2427450 R 416870 CDS YP_001033709.1 125625226 4798587 2428725..2429573 1 NC_009004.1 PF01418: Helix-turn-helix domain, RpiR family , PF01380: SIS domain sugar isomerase domain; Conserved hypothetical protein; RpiR family transcriptional regulator 2429573 gntR 4798587 gntR Lactococcus lactis subsp. cremoris MG1363 RpiR family transcriptional regulator YP_001033709.1 2428725 D 416870 CDS YP_001033710.1 125625227 4798210 2429612..2429920 1 NC_009004.1 hypothetical protein 2429920 4798210 llmg_2471 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033710.1 2429612 D 416870 CDS YP_001033711.1 125625228 4797711 complement(2429992..2430777) 1 NC_009004.1 IPR004843: Metallophosphoesterase; hypothetical protein 2430777 4797711 llmg_2472 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033711.1 2429992 R 416870 CDS YP_001033712.1 125625229 4796709 complement(2430908..2431153) 1 NC_009004.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 2431153 rpsR 4796709 rpsR Lactococcus lactis subsp. cremoris MG1363 30S ribosomal protein S18 YP_001033712.1 2430908 R 416870 CDS YP_001033713.1 125625230 4797809 complement(2431325..2431825) 1 NC_009004.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 2431825 ssbB 4797809 ssbB Lactococcus lactis subsp. cremoris MG1363 single-stranded DNA-binding protein YP_001033713.1 2431325 R 416870 CDS YP_001033714.1 125625231 4798594 complement(2431855..2432148) 1 NC_009004.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 2432148 rpsF 4798594 rpsF Lactococcus lactis subsp. cremoris MG1363 30S ribosomal protein S6 YP_001033714.1 2431855 R 416870 CDS YP_001033715.1 125625232 4799148 complement(2432342..2433196) 1 NC_009004.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase 2433196 bacA 4799148 bacA Lactococcus lactis subsp. cremoris MG1363 undecaprenyl pyrophosphate phosphatase YP_001033715.1 2432342 R 416870 CDS YP_001033716.1 125625233 4798635 2433658..2435184 1 NC_009004.1 Region start changed from 2433717 to 2433657 (60 bases); lysine specific permease 2435184 4798635 llmg_2477 Lactococcus lactis subsp. cremoris MG1363 lysine specific permease YP_001033716.1 2433658 D 416870 CDS YP_001033717.1 125625234 4796796 complement(2435218..2436879) 1 NC_009004.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 2436879 dnaX 4796796 dnaX Lactococcus lactis subsp. cremoris MG1363 DNA polymerase III subunits gamma and tau YP_001033717.1 2435218 R 416870 CDS YP_001033718.1 125625235 4798402 complement(2436925..2437566) 1 NC_009004.1 IPR011009: Protein kinase-like; hypothetical protein 2437566 4798402 llmg_2479 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033718.1 2436925 R 416870 CDS YP_001033719.1 125625236 4796623 complement(2437598..2438086) 1 NC_009004.1 GAF; hypothetical protein 2438086 4796623 llmg_2480 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033719.1 2437598 R 416870 CDS YP_001033720.1 125625237 4796617 2438170..2438442 1 NC_009004.1 PF01817: Chorismate mutase type II, TIGR01805: CM_mono_grmpos: chorismate mutase; Family membership; hypothetical protein 2438442 4796617 llmg_2481 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033720.1 2438170 D 416870 CDS YP_001033721.1 125625238 4796586 complement(2438477..2438926) 1 NC_009004.1 hypothetical protein 2438926 4796586 llmg_2482 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033721.1 2438477 R 416870 CDS YP_001033722.1 125625239 4797469 2439144..2439344 1 NC_009004.1 hypothetical protein 2439344 4797469 llmg_2483 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033722.1 2439144 D 416870 CDS YP_001033723.1 125625240 4797464 complement(2439405..2440745) 1 NC_009004.1 PF00120: Glutamine synthetase, catalytic domain, TIGR00653: glutamine synthetase, type I; High confidence in function and specificity; GlnA protein 2440745 glnA 4797464 glnA Lactococcus lactis subsp. cremoris MG1363 GlnA protein YP_001033723.1 2439405 R 416870 CDS YP_001033724.1 125625241 4797312 complement(2440807..2441172) 1 NC_009004.1 GLNR, MerR family transcriptional regulator; High confidence in function and specificity; glutamine synthetase 2441172 glnR 4797312 glnR Lactococcus lactis subsp. cremoris MG1363 glutamine synthetase YP_001033724.1 2440807 R 416870 CDS YP_001033725.1 125625242 4796835 complement(2441273..2441710) 1 NC_009004.1 PF01451: Low molecular weight phosphotyrosine protein phosphatase; High confidence in function and specificity; protein-tyrosine-phosphatase 2441710 ptpL 4796835 ptpL Lactococcus lactis subsp. cremoris MG1363 protein-tyrosine-phosphatase YP_001033725.1 2441273 R 416870 CDS YP_001033726.1 125625243 4797675 complement(2441855..2442856) 1 NC_009004.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 2442856 ruvB 4797675 ruvB Lactococcus lactis subsp. cremoris MG1363 Holliday junction DNA helicase RuvB YP_001033726.1 2441855 R 416870 CDS YP_001033727.1 125625244 4797168 complement(2443004..2443597) 1 NC_009004.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 2443597 ruvA 4797168 ruvA Lactococcus lactis subsp. cremoris MG1363 Holliday junction DNA helicase RuvA YP_001033727.1 2443004 R 416870 CDS YP_001033728.1 125625245 4797473 complement(2443649..2445619) 1 NC_009004.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 2445619 mutL 4797473 mutL Lactococcus lactis subsp. cremoris MG1363 DNA mismatch repair protein YP_001033728.1 2443649 R 416870 CDS YP_001033729.1 125625246 4798617 complement(2445749..2446444) 1 NC_009004.1 hypothetical protein 2446444 4798617 llmg_2490 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033729.1 2445749 R 416870 CDS YP_001033730.1 125625247 4797478 complement(2446554..2449076) 1 NC_009004.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 2449076 mutS 4797478 mutS Lactococcus lactis subsp. cremoris MG1363 DNA mismatch repair protein MutS YP_001033730.1 2446554 R 416870 CDS YP_001033731.1 125625248 4798536 complement(2449192..2449539) 1 NC_009004.1 hypothetical protein 2449539 4798536 llmg_2492 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033731.1 2449192 R 416870 CDS YP_001033732.1 125625249 4798655 2449740..2450915 1 NC_009004.1 PF00872: Transposase, Mutator family; Conserved hypothetical protein; transposase for insertion sequence element IS905N 2450915 tnp905 4798655 tnp905 Lactococcus lactis subsp. cremoris MG1363 transposase for insertion sequence element IS905N YP_001033732.1 2449740 D 416870 CDS YP_001033733.1 125625250 4797816 complement(2451026..2451907) 1 NC_009004.1 TIGR01505: 2-hydroxy-3-oxopropionate reductase; Conserved hypothetical protein; 3-hydroxyisobutyrate dehydrogenase 2451907 ywjF 4797816 ywjF Lactococcus lactis subsp. cremoris MG1363 3-hydroxyisobutyrate dehydrogenase YP_001033733.1 2451026 R 416870 CDS YP_001033734.1 125625251 4797436 complement(2451950..2452270) 1 NC_009004.1 Region start changed from 2452228 to 2452270 (42 bases); hypothetical protein 2452270 4797436 llmg_2495 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033734.1 2451950 R 416870 CDS YP_001033735.1 125625252 4796906 complement(2452387..2452764) 1 NC_009004.1 PF07843: Protein of unknown function (DUF1634); hypothetical protein 2452764 4796906 llmg_2496 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033735.1 2452387 R 416870 CDS YP_001033736.1 125625253 4797561 complement(2452764..2453615) 1 NC_009004.1 PF01925: Protein of unknown function DUF81; hypothetical protein 2453615 4797561 llmg_2497 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033736.1 2452764 R 416870 CDS YP_001033737.1 125625254 4796734 2453799..2453978 1 NC_009004.1 hypothetical protein 2453978 4796734 llmg_2498 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033737.1 2453799 D 416870 CDS YP_001033738.1 125625255 4796825 2454098..2455609 1 NC_009004.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 2455609 4796825 llmg_2499 Lactococcus lactis subsp. cremoris MG1363 glucose-6-phosphate 1-dehydrogenase YP_001033738.1 2454098 D 416870 CDS YP_001033739.1 125625256 4798538 complement(2455805..2456332) 1 NC_009004.1 TIGR01668: HAD-superfamily, subfamily IIIA phosphatase; hypothetical protein 2456332 4798538 llmg_2500 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033739.1 2455805 R 416870 CDS YP_001033740.1 125625257 4796631 complement(2456461..2457600) 1 NC_009004.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 2457600 dnaJ 4796631 dnaJ Lactococcus lactis subsp. cremoris MG1363 molecular chaperone DnaJ YP_001033740.1 2456461 R 416870 CDS YP_001033741.1 125625258 4797808 complement(2458449..2459171) 1 NC_009004.1 PF01177: Asp/Glu/Hydantoin racemase; High confidence in function and specificity; RacD protein 2459171 racD 4797808 racD Lactococcus lactis subsp. cremoris MG1363 RacD protein YP_001033741.1 2458449 R 416870 CDS YP_001033742.1 125625259 4797911 complement(2459203..2460429) 1 NC_009004.1 hypothetical protein 2460429 4797911 llmg_2505 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033742.1 2459203 R 416870 CDS YP_001033743.1 125625260 4797108 complement(2460441..2462318) 1 NC_009004.1 Asparagine synthetase (glutamine-hydrolyzing), PF00733: Asparagine synthase; High confidence in function and specificity; asparagine synthase 2462318 asnH 4797108 asnH Lactococcus lactis subsp. cremoris MG1363 asparagine synthase YP_001033743.1 2460441 R 416870 CDS YP_001033744.1 125625261 4797218 complement(2462440..2463825) 1 NC_009004.1 PF05257: CHAP domain, IPR011050: Pectin lyase- like; Conserved hypothetical protein; secreted 45 kDa protein precursor 2463825 usp45 4797218 usp45 Lactococcus lactis subsp. cremoris MG1363 secreted 45 kDa protein precursor YP_001033744.1 2462440 R 416870 CDS YP_001033745.1 125625262 4798305 complement(2463929..2464456) 1 NC_009004.1 Region start changed from 2464405 to 2464456 (51 bases); cell shape determining protein mreD 2464456 4798305 llmg_2508 Lactococcus lactis subsp. cremoris MG1363 cell shape determining protein mreD YP_001033745.1 2463929 R 416870 CDS YP_001033746.1 125625263 4798257 complement(2464535..2465410) 1 NC_009004.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 2465410 mreC 4798257 mreC Lactococcus lactis subsp. cremoris MG1363 rod shape-determining protein MreC YP_001033746.1 2464535 R 416870 CDS YP_001033747.1 125625264 4797526 2465701..2466141 1 NC_009004.1 mutator protein 2466141 mutT 4797526 mutT Lactococcus lactis subsp. cremoris MG1363 mutator protein YP_001033747.1 2465701 D 416870 CDS YP_001033748.1 125625265 4797489 complement(2466170..2466844) 1 NC_009004.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 2466844 rpiA 4797489 rpiA Lactococcus lactis subsp. cremoris MG1363 ribose-5-phosphate isomerase A YP_001033748.1 2466170 R 416870 CDS YP_001033749.1 125625266 4797184 complement(2466928..2467611) 1 NC_009004.1 IPR000595: cNMP_binding , CRP/FNR family of transcription regulators; Family membership; transcriptional regulator 2467611 rcfB 4797184 rcfB Lactococcus lactis subsp. cremoris MG1363 transcriptional regulator YP_001033749.1 2466928 R 416870 CDS YP_001033750.1 125625267 4798542 complement(2467698..2468918) 1 NC_009004.1 Region start changed from 2468930 to 2468918 (-12 bases); transporter 2468918 4798542 llmg_2513 Lactococcus lactis subsp. cremoris MG1363 transporter YP_001033750.1 2467698 R 416870 CDS YP_001033751.1 125625268 4796687 complement(2468981..2469418) 1 NC_009004.1 PF00582: Universal stress protein family; hypothetical protein 2469418 4796687 llmg_2514 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033751.1 2468981 R 416870 CDS YP_001033752.1 125625269 4797085 complement(2469438..2469641) 1 NC_009004.1 hypothetical protein 2469641 4797085 llmg_2515 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033752.1 2469438 R 416870 CDS YP_001033753.1 125625270 4798117 complement(2469872..2474182) 1 NC_009004.1 TIGR00241: CoA-substrate-specific enzyme activase, , PF01869: BadF/BadG/BcrA/BcrD ATPase; Family membership; hypothetical protein 2474182 4798117 llmg_2516 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033753.1 2469872 R 416870 CDS YP_001033754.1 125625271 4797087 2474592..2475206 1 NC_009004.1 Region start changed from 2474583 to 2474592 (-9 bases); hypothetical protein 2475206 4797087 llmg_2517 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033754.1 2474592 D 416870 CDS YP_001033755.1 125625272 4796895 complement(2475290..2476276) 1 NC_009004.1 Region start changed from 2476018 to 2476276 (258 bases); ribosomal small subunit pseudouridine synthase A 2476276 4796895 llmg_2518 Lactococcus lactis subsp. cremoris MG1363 ribosomal small subunit pseudouridine synthase A YP_001033755.1 2475290 R 416870 CDS YP_001033756.1 125625273 4796878 complement(2476285..2476998) 1 NC_009004.1 hypothetical protein 2476998 4796878 llmg_2520 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033756.1 2476285 R 416870 CDS YP_001033757.1 125625274 4798071 2477220..2478587 1 NC_009004.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 2478587 trmE 4798071 trmE Lactococcus lactis subsp. cremoris MG1363 tRNA modification GTPase TrmE YP_001033757.1 2477220 D 416870 CDS YP_001033758.1 125625275 4799006 complement(2478636..2479373) 1 NC_009004.1 hypothetical protein 2479373 4799006 llmg_2522 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033758.1 2478636 R 416870 CDS YP_001033759.1 125625276 4798184 complement(2479373..2481373) 1 NC_009004.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 2481373 recG 4798184 recG Lactococcus lactis subsp. cremoris MG1363 ATP-dependent DNA helicase RecG YP_001033759.1 2479373 R 416870 CDS YP_001033760.1 125625277 4799117 complement(2481512..2481877) 1 NC_009004.1 TIGR00686: Alkylphosphonate utilization operon protein PhnA; Conserved hypothetical protein; alkylphosphonate uptake protein 2481877 phnA 4799117 phnA Lactococcus lactis subsp. cremoris MG1363 alkylphosphonate uptake protein YP_001033760.1 2481512 R 416870 CDS YP_001033761.1 125625278 4796699 complement(2481927..2483105) 1 NC_009004.1 PF00589: Phage integrase; Conserved hypothetical protein; integrase 2483105 ps601 4796699 ps601 Lactococcus lactis subsp. cremoris MG1363 integrase YP_001033761.1 2481927 R 416870 CDS YP_001033762.1 125625279 4798291 complement(2483633..2484235) 1 NC_009004.1 IPR010982: Lambda repressor-like, DNA-binding; hypothetical protein 2484235 ps602 4798291 ps602 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033762.1 2483633 R 416870 CDS YP_001033763.1 125625280 4797322 2484619..2485311 1 NC_009004.1 hypothetical protein 2485311 ps603 4797322 ps603 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033763.1 2484619 D 416870 CDS YP_001033764.1 125625281 4797316 2485565..2486098 1 NC_009004.1 phage associated; hypothetical protein 2486098 ps604 4797316 ps604 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033764.1 2485565 D 416870 CDS YP_001033765.1 125625282 4797302 2486091..2486372 1 NC_009004.1 IPR009061: DNA binding, phage associated; hypothetical protein 2486372 ps605 4797302 ps605 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033765.1 2486091 D 416870 CDS YP_001033766.1 125625283 4797295 2486415..2486654 1 NC_009004.1 Phage associated; hypothetical protein 2486654 ps606 4797295 ps606 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033766.1 2486415 D 416870 CDS YP_001033767.1 125625284 4797251 2486651..2486905 1 NC_009004.1 CDS; hypothetical protein 2486905 4797251 llmg_2531 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033767.1 2486651 D 416870 CDS YP_001033768.1 125625285 4798187 2486902..2487231 1 NC_009004.1 hypothetical protein 2487231 ps608 4798187 ps608 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033768.1 2486902 D 416870 CDS YP_001033769.1 125625286 4797945 2487340..2488134 1 NC_009004.1 hypothetical protein 2488134 ps609 4797945 ps609 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033769.1 2487340 D 416870 CDS YP_001033770.1 125625287 4797938 2488145..2489773 1 NC_009004.1 Similar to prophage ps105 in L. lactis IL1403, DNA primase, PF03288: Poxvirus D5 protein-like; hypothetical protein 2489773 ps610 4797938 ps610 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033770.1 2488145 D 416870 CDS YP_001033771.1 125625288 4797924 2490001..2490543 1 NC_009004.1 Similar to prophage ps104 in L. lactis IL1403; hypothetical protein 2490543 ps611 4797924 ps611 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033771.1 2490001 D 416870 CDS YP_001033772.1 125625289 4797905 2490816..2491118 1 NC_009004.1 hypothetical protein 2491118 ps612 4797905 ps612 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033772.1 2490816 D 416870 CDS YP_001033773.1 125625290 4797900 2491192..2491602 1 NC_009004.1 Similar to prophage ps102, PF05263: Protein of unknown function DUF722; hypothetical protein 2491602 ps613 4797900 ps613 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033773.1 2491192 D 416870 CDS YP_001033774.1 125625291 4797876 2491626..2491949 1 NC_009004.1 Similar to ps101 in L. lactis IL1403; hypothetical protein 2491949 ps614 4797876 ps614 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033774.1 2491626 D 416870 CDS YP_001033775.1 125625292 4797877 complement(2492509..2493519) 1 NC_009004.1 TIGR01534: Glyceraldehyde-3-phosphate dehydrogenase, type I, PF02800: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; High confidence in function and specificity; glyceraldehyde 3-phosphate dehydrogenase 2493519 gapB 4797877 gapB Lactococcus lactis subsp. cremoris MG1363 glyceraldehyde 3-phosphate dehydrogenase YP_001033775.1 2492509 R 416870 CDS YP_001033776.1 125625293 4797420 complement(2493797..2494309) 1 NC_009004.1 hypothetical protein 2494309 4797420 llmg_2540 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033776.1 2493797 R 416870 CDS YP_001033777.1 125625294 4796973 2494447..2497140 1 NC_009004.1 Specificity unclear; cation transporting ATPase 2497140 4796973 llmg_2541 Lactococcus lactis subsp. cremoris MG1363 cation transporting ATPase YP_001033777.1 2494447 D 416870 CDS YP_001033778.1 125625295 4796945 complement(2497182..2497655) 1 NC_009004.1 Region start changed from 2497709 to 2497655 (-54 bases); HTH-type transcriptional regulator 2497655 4796945 llmg_2542 Lactococcus lactis subsp. cremoris MG1363 HTH-type transcriptional regulator YP_001033778.1 2497182 R 416870 CDS YP_001033779.1 125625296 4796971 2497834..2498853 1 NC_009004.1 hypothetical protein 2498853 4796971 llmg_2543 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033779.1 2497834 D 416870 CDS YP_001033780.1 125625297 4797154 2499079..2499534 1 NC_009004.1 membrane protein; hypothetical protein 2499534 4797154 llmg_2544 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033780.1 2499079 D 416870 CDS YP_001033781.1 125625298 4798481 complement(2505530..2505922) 1 NC_009004.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 2505922 rpsI 4798481 rpsI Lactococcus lactis subsp. cremoris MG1363 30S ribosomal protein S9 YP_001033781.1 2505530 R 416870 CDS YP_001033782.1 125625299 4798926 complement(2505942..2506388) 1 NC_009004.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 2506388 rplM 4798926 rplM Lactococcus lactis subsp. cremoris MG1363 50S ribosomal protein L13 YP_001033782.1 2505942 R 416870 CDS YP_001033783.1 125625300 4797889 2506786..2507856 1 NC_009004.1 hypothetical protein 2507856 4797889 llmg_2547 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033783.1 2506786 D 416870 CDS YP_001033784.1 125625301 4797121 2507872..2508543 1 NC_009004.1 hypothetical protein 2508543 4797121 llmg_2548 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033784.1 2507872 D 416870 CDS YP_001033785.1 125625302 4798110 2508690..2509568 1 NC_009004.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease HIII 2509568 rnhA 4798110 rnhA Lactococcus lactis subsp. cremoris MG1363 ribonuclease HIII YP_001033785.1 2508690 D 416870 CDS YP_001033786.1 125625303 4797335 2509580..2510206 1 NC_009004.1 Signal peptidase I (Leader peptidase I)., TIGR02227: Peptidase S26A, signal peptidase I; High confidence in function and specificity; SipL protein 2510206 sipL 4797335 sipL Lactococcus lactis subsp. cremoris MG1363 SipL protein YP_001033786.1 2509580 D 416870 CDS YP_001033787.1 125625304 4797800 complement(2510254..2511069) 1 NC_009004.1 TIGR01743: purR_Bsub, PF00156: Phosphoribosyl transferase domain; High confidence in function and specificity; pur operon repressor 2511069 purR 4797800 purR Lactococcus lactis subsp. cremoris MG1363 pur operon repressor YP_001033787.1 2510254 R 416870 CDS YP_001033788.1 125625305 4797685 complement(2511357..2511644) 1 NC_009004.1 hypothetical protein 2511644 4797685 llmg_2552 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033788.1 2511357 R 416870 CDS YP_001033789.1 125625306 4796929 complement(2511669..2512325) 1 NC_009004.1 membrane protein; hypothetical protein 2512325 4796929 llmg_2553 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033789.1 2511669 R 416870 CDS YP_001033790.1 125625307 4798292 complement(2512328..2513755) 1 NC_009004.1 membrane protein; hypothetical protein 2513755 4798292 llmg_2554 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033790.1 2512328 R 416870 CDS YP_001033791.1 125625308 4797272 complement(2513755..2514018) 1 NC_009004.1 membrane protein; hypothetical protein 2514018 4797272 llmg_2555 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033791.1 2513755 R 416870 CDS YP_001033792.1 125625309 4797421 complement(2514375..2516504) 1 NC_009004.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 2516504 fusA 4797421 fusA Lactococcus lactis subsp. cremoris MG1363 elongation factor G YP_001033792.1 2514375 R 416870 CDS YP_001033793.1 125625310 4797556 complement(2516765..2517232) 1 NC_009004.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 2517232 rpsG 4797556 rpsG Lactococcus lactis subsp. cremoris MG1363 30S ribosomal protein S7 YP_001033793.1 2516765 R 416870 CDS YP_001033794.1 125625311 4799037 complement(2517251..2517664) 1 NC_009004.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 2517664 rpsL 4799037 rpsL Lactococcus lactis subsp. cremoris MG1363 30S ribosomal protein S12 YP_001033794.1 2517251 R 416870 CDS YP_001033795.1 125625312 4797225 complement(2518096..2518257) 1 NC_009004.1 hypothetical protein 2518257 4797225 llmg_2559 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033795.1 2518096 R 416870 CDS YP_001033796.1 125625313 4797426 2519311..2520615 1 NC_009004.1 D-alanyl-D-alanine carboxypeptidase precursor, PF00768: D-alanyl-D-alanine carboxypeptidase; High confidence in function and specificity; DacA protein 2520615 dacA 4797426 dacA Lactococcus lactis subsp. cremoris MG1363 DacA protein YP_001033796.1 2519311 D 416870 CDS YP_001033797.1 125625314 4798871 complement(2520690..2521577) 1 NC_009004.1 Pf06800: Sugartransport protein, TIGR00776 RhaT: RhaT L-rhamnose-proton symporter family protein; Family membership; glucose uptake protein glcU 2521577 glcU 4798871 glcU Lactococcus lactis subsp. cremoris MG1363 glucose uptake protein glcU YP_001033797.1 2520690 R 416870 CDS YP_001033798.1 125625315 4797047 complement(2521703..2522338) 1 NC_009004.1 Pfam: rRNA methylase; Family membership; hypothetical protein 2522338 4797047 llmg_2562 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033798.1 2521703 R 416870 CDS YP_001033799.1 125625316 4797479 complement(2522482..2523423) 1 NC_009004.1 PF04055: Radical SAM superfamily, TIGR01212 family: radical SAM protein; Family membership; hypothetical protein 2523423 4797479 llmg_2563 Lactococcus lactis subsp. cremoris MG1363 hypothetical protein YP_001033799.1 2522482 R 416870 CDS