-- dump date   	20140619_125330
-- class       	Genbank::CDS
-- table       	cds_note
-- id	note
YP_001031366.1	binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.
YP_001031367.1	binds the polymerase to DNA and acts as a sliding clamp
YP_001031368.1	ATP-dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent helicase and DNA-dependent ATPase; High confidence in function and specificity
YP_001031369.1	UvrD/REP helicase; High confidence in function and specificity
YP_001031370.1	Bacterial protein of unknown function DUF951
YP_001031371.1	Lambda repressor-like, DNA-binding, Helix-turn- helix
YP_001031372.1	translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1
YP_001031373.1	DNA binding Helix-turn-helix motif; Conserved hypothetical protein
YP_001031377.1	Enables the recycling of peptidyl-tRNAs produced at termination of translation
YP_001031378.1	Transcription-repair coupling factor, CarD- like/TRCF domain; High confidence in function and specificity
YP_001031379.1	RNA-binding S4; Conserved hypothetical protein
YP_001031381.1	Nucleic acid-binding OB-fold, RNA binding S1 domain; Conserved hypothetical protein
YP_001031382.1	COG: Beta-lactamase class A; Family membership
YP_001031383.1	PP-loop family; High confidence in function and specificity
YP_001031386.1	[KO:K02799 K02800], PTS system, mannitol-specific IIBC component (EIIBC-Mtl), Phosphotransferase system, EIIC; High confidence in function and specificity
YP_001031387.1	PRD domain; High confidence in function and specificity
YP_001031388.1	PTS system, mannitol-specific IIABC component (EIIABC-Mtl), Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; High confidence in function and specificity
YP_001031389.1	Mannitol-1-phosphate 5-dehydrogenase; High confidence in function and specificity
YP_001031392.1	nucleic acid binding motif, phage associated
YP_001031394.1	Similar to ps105 from IL1403, Phage associated; Family membership
YP_001031401.1	Similar to ps113 of IL1403, Protein of unknown function (DUF1655), Phage associated
YP_001031402.1	Lambda repressor-like, DNA-binding, Helix-turn- helix
YP_001031404.1	Lambda repressor-like, DNA-binding
YP_001031405.1	Family membership
YP_001031406.1	Conserved hypothetical protein
YP_001031407.1	Similar to ps117 from IL1403
YP_001031408.1	nucleic acid binding motif
YP_001031411.1	Similar to ps119 from IL1403
YP_001031412.1	Similar to ps120 from IL1403
YP_001031413.1	Conserved hypothetical protein
YP_001031414.1	IstB-like ATP-binding protein; Conserved hypothetical protein
YP_001031416.1	phage protein
YP_001031418.1	Similar to lciA, Lactococcin A immunity protein; Conserved hypothetical protein
YP_001031419.1	DNA breaking-rejoining enzyme, catalytic core, Tyrosine recombinase xerD; Conserved hypothetical protein
YP_001031420.1	Bacterial protein of unknown function DUF915; Family membership
YP_001031424.1	GCN5-related N-acetyltransferase; Function unclear
YP_001031426.1	Sulfate transporter family, sulP: sulfate permease; Family membership
YP_001031427.1	High confidence in function and specificity
YP_001031428.1	Amino-acid acetyltransferase, GCN5-related N- acetyltransferase; Family membership
YP_001031429.1	catalyzes the transamination of the aromatic amino acid forming a ketoacid; first step in aromatic amino acid degradation in lactococci
YP_001031430.1	involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA
YP_001031431.1	RGG_Cterm: transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Conserved hypothetical protein
YP_001031432.1	Major facilitator superfamily MFS_1; Family membership
YP_001031433.1	E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide
YP_001031434.1	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, PDHac_trf_long: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; High confidence in function and specificity
YP_001031435.1	1-deoxy-D-xylulose-5-phosphate synthase (DXP synthase); High confidence in function and specificity
YP_001031437.1	Lipoyltransferase and lipoate-protein ligase; High confidence in function and specificity
YP_001031438.1	High confidence in function and specificity
YP_001031439.1	Metal-dependent phosphohydrolase, HD region; Family membership
YP_001031441.1	catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_001031442.1	OsmC-like protein; High confidence in function and specificity
YP_001031443.1	Amino acid permease-associated region; Function unclear
YP_001031445.1	involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY
YP_001031446.1	Cof-subfamily: Cof-like hydrolase; Family membership
YP_001031447.1	ABC transporter related; Specificity unclear
YP_001031448.1	yiaA/B two helix domain; Conserved hypothetical protein
YP_001031449.1	homology to 3-oxoacyl-[acyl-carrier-protein] reductase, Short-chain dehydrogenase/reductase SDR; Function unclear
YP_001031450.1	Conserved hypothetical protein
YP_001031451.1	High confidence in function and specificity
YP_001031452.1	Region start changed from 86382 to 86376 (-6 bases)
YP_001031453.1	OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase, Cystathionine beta-lyases/cystathionine gamma-synthases; High confidence in function and specificity
YP_001031454.1	Short-chain dehydrogenase/reductase SDR, homology to 3-oxoacyl-[acyl-carrier-protein] reductase; Function unclear
YP_001031455.1	Universal stress protein family; Conserved hypothetical protein
YP_001031457.1	Esterase/lipase/thioesterase
YP_001031458.1	Family membership
YP_001031459.1	contains FMN-binding split barrel domain; Function unclear
YP_001031460.1	in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif
YP_001031461.1	some L32 proteins have zinc finger motifs consisting of CXXC while others do not
YP_001031462.1	High confidence in function and specificity
YP_001031463.1	Conserved hypothetical protein
YP_001031464.1	ParB-like partition protein, ParB-like nuclease domain; High confidence in function and specificity
YP_001031465.1	High confidence in function and specificity
YP_001031466.1	GCN5-related N-acetyltransferase, Acetyltransferase (GNAT) family; High confidence in function and specificity
YP_001031468.1	ABC transporter related; Family membership
YP_001031470.1	S-adenosylmethionine-dependent methyltransferase, SAM (and some other nucleotide) binding motif; Family membership
YP_001031472.1	methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype
YP_001031473.1	in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase
YP_001031474.1	Polysaccharide deacetylase,  Signal peptide and one TMH; Family membership
YP_001031475.1	guanosine-3',5'-bis(diphosphate) 3'- pyrophosphohydrolase ((ppGpp)ase) (Penta-phosphate guanosine-3'- pyrophosphohydrolase); High confidence in function and specificity
YP_001031476.1	Glycosyl transferase, family 2; Function unclear
YP_001031477.1	hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine
YP_001031478.1	Protein of unknown function DUF1211
YP_001031479.1	hydrolase (HAD superfamily) (PFAM), Haloacid dehalogenase-like hydrolase; Conserved hypothetical protein
YP_001031480.1	Amino acid permease-associated region, COG: Amino acid transporters, PFAM: Amino acid permease, 2A0306: amino acid transporter; Conserved hypothetical protein
YP_001031482.1	Bacterial regulatory protein, MarR; Conserved hypothetical protein
YP_001031483.1	transposase helper protein for IS904
YP_001031484.1	Integrase, catalytic region; Conserved hypothetical protein
YP_001031485.1	acyl carrier protein phosphodiesterase, fatty acid and phospholipid metabolism; High confidence in function and specificity
YP_001031486.1	functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins
YP_001031487.1	catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive
YP_001031488.1	Phosphocarrier protein HPr (Histidine-containing protein)., PTS HPr component phosphorylation site, PTS_HPr_family: phosphocarrier protein HPr; High confidence in function and specificity
YP_001031489.1	Phosphoenolpyruvate-protein phosphotransferase , Phosphotransferase system, enzyme I, PEP-utilising enzyme, TIM barrel domain, PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase; High confidence in function and specificity
YP_001031492.1	Esterase/lipase/thioesterase; Conserved hypothetical protein
YP_001031494.1	EmrE protein (Methyl viologen resistance protein C) , (Ethidium resistance protein); Specificity unclear
YP_001031495.1	Multidrug resistance protein 1 (Multidrug-efflux transporter 1)., General substrate transporter Major Facilitator Superfamily, 2_A_01_02: Multidrug resistance protein; High confidence in function and specificity
YP_001031496.1	Glycosyl transferase, family 2, Bactoprenol glucosyl transferase; High confidence in function and specificity
YP_001031497.1	predicted transmembrane protein, multiple transmembrane segments
YP_001031498.1	ATP-binding region, ATPase-like; Conserved hypothetical protein
YP_001031499.1	Permeases of the major facilitator superfamily, von Willebrand factor, type A
YP_001031500.1	catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming
YP_001031501.1	catalyzes the formation of arginine from (N-L-arginino)succinate
YP_001031502.1	Multidrug resistance protein, Integral membrane protein; Conserved hypothetical protein
YP_001031503.1	Tetracyclin repressor-like, C-terminal; Conserved hypothetical protein
YP_001031504.1	protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates
YP_001031505.1	Region start changed from 139163 to 139136 (27 bases)
YP_001031506.1	Single-stranded nucleic acid binding , Domain R3H and KH; Conserved hypothetical protein; ORF1
YP_001031507.1	in Escherichia coli transcription of this gene is enhanced by polyamines
YP_001031508.1	Aldo/keto reductase, Aldo/keto reductase; High confidence in function and specificity
YP_001031511.1	Abortive infection protein, CAAX amino terminal protease
YP_001031512.1	Conserved hypothetical protein
YP_001031513.1	similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function
YP_001031515.1	Predicted integral membrane protein
YP_001031516.1	3-oxoacyl-[acyl-carrier-protein] reductase , Short- chain dehydrogenase/reductase SDR\, Fatty acid biosynthesis pathway; High confidence in function and specificity
YP_001031518.1	3-oxoacyl-[acyl-carrier-protein] reductase, Short- chain dehydrogenase/reductase SDR, Fatty acid biosynthesis pathway; High confidence in function and specificity
YP_001031519.1	Homeodomain-like, Bacterial regulatory proteins, tetR family
YP_001031520.1	1,4-alpha-glucan branching enzyme , Glycogen branching enzyme, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6- glucosyl- transferase, Alpha amylase, catalytic subdomain, Isoamylase N-terminal domain, branching_enzym: 1,4-alpha- glucan branching enzyme; High confidence in function and specificity
YP_001031522.1	FMN-dependent nitroreductase (Dihydropteridine reductase); Conserved hypothetical protein
YP_001031523.1	Homeodomain-like, Bacterial regulatory proteins, tetR family; Conserved hypothetical protein
YP_001031524.1	Bacterial adhesion, Collagen binding domain, Predicted Signal sequence
YP_001031525.1	Lambda repressor-like, DNA-binding
YP_001031526.1	Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr)
YP_001031528.1	CoA binding domain
YP_001031529.1	DNA/RNA non-specific endonuclease; High confidence in function and specificity
YP_001031530.1	Transmembrane protein
YP_001031531.1	Heme/copper-type cytochrome/quinol oxidases, subunit 1, COG: 0843
YP_001031532.1	broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor
YP_001031533.1	CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
YP_001031535.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain
YP_001031536.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA
YP_001031537.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA
YP_001031538.1	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases, Similar to GatA; High confidence in function and specificity
YP_001031539.1	cation efflux protein (); High confidence in function and specificity
YP_001031540.1	Cold-shock protein, DNA-binding; Conserved hypothetical protein
YP_001031541.1	High confidence in function and specificity
YP_001031542.1	Rhomboid-like protein; High confidence in function and specificity
YP_001031543.1	Conserved hypothetical protein
YP_001031544.1	Lactoylglutathione lyase , Methylglyoxalase; Aldoketomutase; Glyoxalase I, Ketone-aldehyde mutase; High confidence in function and specificity
YP_001031545.1	Predicted acetyltransferase, Eis type; High confidence in function and specificity
YP_001031547.1	PTS system, lichenan-specific IIC component , Phosphotransferase enzyme II, C component; High confidence in function and specificity
YP_001031550.1	Beta-glucosidase , Gentiobiase; Cellobiase; Beta-D- glucoside glucohydrolase; Amygdalase, Glycoside hydrolase, family 1; High confidence in function and specificity
YP_001031551.1	catalyzes the formation of dUMP from dUTP
YP_001031552.1	5'-nucleotidase precursor , Phosphoesterase-related protein; High confidence in function and specificity
YP_001031554.1	23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance
YP_001031555.1	Oxygen-insensitive NAD(P)H nitroreductase; High confidence in function and specificity
YP_001031556.1	Region start changed from 184692 to 184725 (-33 bases)
YP_001031557.1	catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate
YP_001031558.1	Abortive infection protein
YP_001031559.1	feoB: ferrous iron transport protein B; Conserved hypothetical protein
YP_001031560.1	Transcriptional repressor, C-terminal, FeoA domain; Conserved hypothetical protein
YP_001031561.1	this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress
YP_001031562.1	Conserved hypothetical protein
YP_001031564.1	required for 70S ribosome assembly
YP_001031565.1	Membrane protein of unknown function
YP_001031566.1	Glucose-1-phosphate thymidylyltransferase 1, dTDP- glucose synthase 1; dTDP-glucose pyrophosphorylase 1; High confidence in function and specificity
YP_001031567.1	dTDP-4-dehydrorhamnose 3,5-epimerase, dTDP-4-keto-6- deoxyglucose 3,5-epimerase, dTDP-L-rhamnose synthetase; High confidence in function and specificity
YP_001031570.1	Probable dTDP-4-dehydrorhamnose reductase, dTDP-4- keto- L-rhamnose reductase, rmlD: dTDP-4-dehydrorhamnose reductase; High confidence in function and specificity
YP_001031571.1	polysaccharide biosynthesis protein; High confidence in function and specificity
YP_001031572.1	Glycosyl transferase, family 2,  polysaccharide synthesis protein; High confidence in function and specificity
YP_001031573.1	ABC-2 type transporter; Conserved hypothetical protein
YP_001031574.1	High confidence in function and specificity
YP_001031575.1	Conserved hypothetical protein
YP_001031576.1	Glycosyl transferase, family 2; High confidence in function and specificity
YP_001031577.1	Rhamnan synthesis protein F, polysaccharide biosynthesis protein; High confidence in function and specificity
YP_001031578.1	Glycosyl transferase, family 2; High confidence in function and specificity
YP_001031580.1	Glycosyl transferase, family 2; Conserved hypothetical protein
YP_001031581.1	Glycosyl transferase, family 2; Conserved hypothetical protein
YP_001031583.1	Conserved hypothetical protein
YP_001031584.1	High confidence in function and specificity
YP_001031585.1	Polysaccharide biosynthesis protein; Family membership
YP_001031589.1	Glycoside hydrolase, family 25; Family membership
YP_001031590.1	catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate
YP_001031591.1	in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
YP_001031592.1	Probable (di)nucleoside polyphosphate hydrolase., MutT/Nudix family protein; Family membership
YP_001031593.1	GTP-binding protein, HSR1-related; High confidence in function and specificity
YP_001031595.1	Protein of unknown function UPF0044, contains CRS1 / YhbY domain
YP_001031596.1	TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase; High confidence in function and specificity
YP_001031597.1	PF01966.9: Metal-dependent phosphohydrolase, HD subdomain, TIGR00488: conserved hypothetical protein TIGR00488
YP_001031598.1	GCN5-related N-acetyltransferase; Family membership
YP_001031599.1	Domain of unknown function DUF143, TIGR00090: iojap- related protein
YP_001031600.1	contains SAM (and some other nucleotide) binding motif
YP_001031601.1	Protein of unknown function DUF795; Family membership
YP_001031602.1	PF01709.9: Protein of unknown function DUF28
YP_001031603.1	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
YP_001031604.1	Zinc-containing alcohol dehydrogenase superfamily; Family membership
YP_001031606.1	Function unclear
YP_001031607.1	Function unclear
YP_001031608.1	Major facilitator superfamily; Family membership
YP_001031609.1	DNA binding HTH containing; Family membership
YP_001031610.1	a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA
YP_001031611.1	Cof protein, HAD-SF-IIB: predicted HAD-superfamily hydrolase, subfamily IIB; Family membership
YP_001031612.1	Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway
YP_001031613.1	(S)-2-haloacid dehalogenase (Halocarboxylic acid halidohydrolase), Haloacid dehalogenase, type II; High confidence in function and specificity
YP_001031614.1	similar to DhaK; in Lactococcus lactis this protein froms a stable complex with DhaS and activates transcription of the dha operon in the presence of dihydroxyacetone
YP_001031615.1	Dihydroxyacetone kinase (Glycerone kinase) (DHA kinase), DAK2 domain; High confidence in function and specificity
YP_001031616.1	PF03610.4: PTS system fructose subfamily IIA component
YP_001031617.1	Peptidase U34; High confidence in function and specificity
YP_001031618.1	Specificity unclear
YP_001031619.1	PS50193: contains SAM (and some other nucleotide) binding motif; Family membership
YP_001031620.1	High confidence in function and specificity
YP_001031621.1	TIGR00275: conserved hypothetical protein TIGR00275
YP_001031622.1	Protein of unknown function UPF0031; Family membership
YP_001031624.1	Specificity unclear
YP_001031625.1	Specificity unclear
YP_001031627.1	Family membership
YP_001031629.1	catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2
YP_001031630.1	SSF55136: Bacterial regulatory factor, effector; Family membership
YP_001031632.1	Family membership
YP_001031633.1	Family membership
YP_001031636.1	High confidence in function and specificity
YP_001031637.1	Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates
YP_001031638.1	High confidence in function and specificity
YP_001031641.1	contains WD40 repeat domain
YP_001031642.1	with CbiNQ forms the ABC transporter for cobalt import; Lactococcus has two adjacent copies of this gene
YP_001031643.1	with CbiNQ forms the ABC transporter for cobalt import; Lactococcus has two adjacent copies of this gene
YP_001031644.1	High confidence in function and specificity
YP_001031646.1	High confidence in function and specificity
YP_001031647.1	High confidence in function and specificity
YP_001031648.1	High confidence in function and specificity
YP_001031651.1	primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination
YP_001031652.1	contains S1 RNA binding domain; High confidence in function and specificity
YP_001031653.1	metallopeptidase (SprT family); Family membership
YP_001031654.1	catalyzes the formation of inosine from adenosine
YP_001031656.1	Family membership
YP_001031657.1	Conserved hypothetical protein MG423; Family membership
YP_001031658.1	Protein of unknown function DUF1447
YP_001031660.1	Family membership
YP_001031661.1	Region start changed from 294277 to 294343 (-66 bases)
YP_001031662.1	High confidence in function and specificity
YP_001031663.1	in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity
YP_001031667.1	High confidence in function and specificity
YP_001031668.1	High confidence in function and specificity
YP_001031669.1	Region start changed from 300786 to 300798 (-12 bases)
YP_001031670.1	High confidence in function and specificity
YP_001031672.1	High confidence in function and specificity
YP_001031673.1	High confidence in function and specificity
YP_001031674.1	tetracycline resistance protein; High confidence in function and specificity
YP_001031675.1	High confidence in function and specificity
YP_001031676.1	CDF: cation diffusion facilitator family transporter; Family membership
YP_001031677.1	PF03551.4: Transcriptional regulator PadR-like family; Function unclear
YP_001031678.1	ABC transporter ATP binding and permease; High confidence in function and specificity
YP_001031679.1	ABC transporter ATP-binding/membrane spanning protein; High confidence in function and specificity
YP_001031680.1	adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active
YP_001031683.1	Family membership
YP_001031684.1	Major facilitator superfamily; Family membership
YP_001031685.1	Conserved hypothetical protein
YP_001031686.1	BioY family; Specificity unclear
YP_001031687.1	YbaK/prolyl-tRNA synthetase associated region, PF04073.3: YbaK_EbsC: ybaK/ebsC protein
YP_001031688.1	Conserved hypothetical protein
YP_001031689.1	High confidence in function and specificity
YP_001031690.1	High confidence in function and specificity
YP_001031691.1	High confidence in function and specificity
YP_001031692.1	High confidence in function and specificity
YP_001031693.1	High confidence in function and specificity
YP_001031694.1	High confidence in function and specificity
YP_001031695.1	Specificity unclear
YP_001031696.1	Protein of unknown function DUF1393; Conserved hypothetical protein
YP_001031697.1	High confidence in function and specificity
YP_001031698.1	High confidence in function and specificity
YP_001031699.1	High confidence in function and specificity
YP_001031700.1	High confidence in function and specificity
YP_001031701.1	High confidence in function and specificity
YP_001031702.1	High confidence in function and specificity
YP_001031703.1	Also known as transcriptional activator of metCcysK operon cmbR; High confidence in function and specificity
YP_001031704.1	Major facilitator superfamily; Family membership
YP_001031705.1	Aldo/keto reductase; Family membership
YP_001031706.1	Protein of unknown function DUF24; Conserved hypothetical protein
YP_001031707.1	Glyoxalase/extradiol ring-cleavage dioxygenase; Family membership
YP_001031708.1	2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate
YP_001031709.1	High confidence in function and specificity
YP_001031710.1	High confidence in function and specificity
YP_001031711.1	High confidence in function and specificity
YP_001031712.1	involved in a recombinational process of DNA repair, independent of the recBC complex
YP_001031713.1	D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli
YP_001031714.1	D-Ala-D-Ala adding enzym; High confidence in function and specificity
YP_001031715.1	Conserved hypothetical protein
YP_001031716.1	Conserved hypothetical protein
YP_001031717.1	High confidence in function and specificity
YP_001031718.1	High confidence in function and specificity
YP_001031719.1	High confidence in function and specificity
YP_001031720.1	stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein
YP_001031721.1	Similar to cold-shock DEAD-box protein A (ATP- dependent RNA helicase deaD); High confidence in function and specificity
YP_001031723.1	Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome
YP_001031724.1	functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP
YP_001031725.1	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases
YP_001031726.1	catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs
YP_001031727.1	Specificity unclear
YP_001031728.1	Specificity unclear
YP_001031729.1	Protein of unknown function DUF1333
YP_001031732.1	contains CYTH domain., Similar to adenylate cyclases
YP_001031733.1	Protein of unknown function DUF817; Conserved hypothetical protein
YP_001031734.1	Contains region found in RelA / SpoT proteins; Specificity unclear
YP_001031735.1	catalyzes the phosphorylation of NAD to NADP
YP_001031736.1	High confidence in function and specificity
YP_001031737.1	High confidence in function and specificity
YP_001031738.1	Lysine specific permease; High confidence in function and specificity
YP_001031739.1	Similar to NADPH-dependent FMN reductases; Family membership
YP_001031740.1	ApbE-like lipoprotein; High confidence in function and specificity
YP_001031741.1	class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1
YP_001031742.1	High confidence in function and specificity
YP_001031743.1	Region start changed from 383499 to 383544 (-45 bases)
YP_001031744.1	High confidence in function and specificity
YP_001031745.1	High confidence in function and specificity
YP_001031746.1	PF03595.4: C4-dicarboxylate transporter/malic acid transport protein; Family membership
YP_001031747.1	Required for the synthesis of the thiazole moiety
YP_001031748.1	High confidence in function and specificity
YP_001031749.1	PF02566.5: OsmC-like protein
YP_001031750.1	High confidence in function and specificity
YP_001031752.1	catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr)
YP_001031753.1	High confidence in function and specificity
YP_001031754.1	High confidence in function and specificity
YP_001031756.1	Thioredoxin domain 2; Conserved hypothetical protein
YP_001031757.1	t-RNA-binding region; High confidence in function and specificity
YP_001031758.1	FAD-dependent pyridine nucleotide-disulphide oxidoreductase, Pyridine nucleotide-disulphide oxidoreductase; High confidence in function and specificity
YP_001031759.1	binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA
YP_001031760.1	10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring
YP_001031761.1	60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth
YP_001031762.1	Ribonuclease Z (tRNA 3 endonuclease)., Beta- lactamase-like, Metallo-beta-lactamase superfamily; High confidence in function and specificity
YP_001031763.1	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, cztS_silS_copS: heavy metal sensor kinase; High confidence in function and specificity
YP_001031764.1	Response regulator receiver domain, PhoB: Phosphate regulon transcriptional regulatory protein phoB; Conserved hypothetical protein
YP_001031765.1	catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP)
YP_001031766.1	catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA.
YP_001031767.1	PSP1 C-terminal conserved region; High confidence in function and specificity
YP_001031768.1	in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA
YP_001031769.1	Tetrapyrrole (Corrin/Porphyrin) Methylases
YP_001031771.1	Belongs to the ABC-2 integral membrane protein family; Conserved hypothetical protein
YP_001031773.1	High confidence in function and specificity
YP_001031774.1	Transcriptional regulator ,  Cytolysin slyA, InterPro: Bacterial regulatory protein, MarR; High confidence in function and specificity
YP_001031775.1	Mevalonate kinase, GHMP kinases  ATP- binding protein, mevalon_kin: mevalonate kinase; High confidence in function and specificity
YP_001031776.1	Diphosphomevalonate decarboxylase, GHMP kinases ATP-binding protein, mevDPdecarb: diphosphomevalonate decarboxylase; High confidence in function and specificity
YP_001031777.1	GHMP kinases  ATP-binding protein; High confidence in function and specificity
YP_001031778.1	catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate
YP_001031779.1	Manganese and iron superoxide dismutase, Iron/manganese superoxide dismutases, C-terminal domain; High confidence in function and specificity
YP_001031780.1	Carbon starvation protein CstA; Conserved hypothetical protein
YP_001031781.1	Region start changed from 424275 to 424191 (-84 bases)
YP_001031783.1	DEAD/DEAH box helicase
YP_001031784.1	Conserved hypothetical protein
YP_001031785.1	Contains 1 HTH rpiR-type DNA-binding domain; Conserved hypothetical protein
YP_001031787.1	Lichenan- permease IIB component, Phosphotransferase system, lactose/cellobiose-specific IIB subunit, PTS system, Lactose/Cellobiose specific IIB subunit; High confidence in function and specificity
YP_001031788.1	PTS system, lactose-specific IIA component , Lactose- permease IIA component, Phosphotransferase system PTS, lactose/cellobiose-specific IIA subunit, PTS system, Lactose/Cellobiose specific IIA subunit; High confidence in function and specificity
YP_001031789.1	Family membership
YP_001031790.1	PTS system, lichenan-specific IIC component; High confidence in function and specificity
YP_001031791.1	converts 6-phospho-beta-D-glucosyl-(1,4)-D-glucose to glucose and glucose 6-phosphate; required for cellobiose uptake and metabolism
YP_001031794.1	this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB
YP_001031795.2	similar to YegS from E. coli
YP_001031796.1	Probable multiple sugar-binding transport ATP- binding protein; Conserved hypothetical protein
YP_001031797.1	Pyruvate:ferredoxin (flavodoxin) oxidoreductase, Thiamine pyrophosphate enzyme, C-terminal TPP binding domain, pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase; High confidence in function and specificity
YP_001031801.1	catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
YP_001031802.1	GntR family transcriptional regulator; Conserved hypothetical protein
YP_001031803.1	PTS system likely trehalose specific; High confidence in function and specificity
YP_001031804.1	PTS-IIBC-Tre: PTS system, trehalose-specific IIBC component; High confidence in function and specificity
YP_001031805.1	Glycoside transferase, six-hairpin, Glycosyl hydrolase 65 central catalytic domain; High confidence in function and specificity
YP_001031806.1	haloacid dehalogenase-like hydrolase, bPGM: beta- phosphoglucomutase; High confidence in function and specificity
YP_001031807.1	PS50187: Esterase/lipase/thioesterase; Family membership
YP_001031808.1	High confidence in function and specificity
YP_001031809.1	Uncharacterised P-loop hydrolase UPF0079
YP_001031810.1	GCN5-related N-acetyltransferase, Acetyltransferase (GNAT) family; Conserved hypothetical protein
YP_001031811.1	Cell envelope-related transcriptional attenuator domain, lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain; Conserved hypothetical protein
YP_001031812.1	mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability
YP_001031813.1	catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine
YP_001031814.1	High confidence in function and specificity
YP_001031816.1	Serine--pyruvate aminotransferase , (SPT) (Alanine-- glyoxylate aminotransferase)(AGT)., Aminotransferase, class V; High confidence in function and specificity
YP_001031817.1	CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer
YP_001031820.1	domain: Collagen alpha 1(XVII); High confidence in function and specificity
YP_001031825.1	Similar to ldhB; Specificity unclear
YP_001031826.1	Protein of unknown function DUF1003; Conserved hypothetical protein
YP_001031827.1	Conserved hypothetical protein
YP_001031828.1	Family membership
YP_001031829.1	TIGR00730: conserved hypothetical protein
YP_001031830.1	High confidence in function and specificity
YP_001031831.1	PF03412.4: Peptidase C39, bacteriocin processing
YP_001031833.1	Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria.
YP_001031834.1	Function unclear
YP_001031835.1	PF06271.1: RDD family protein, contains AL9 export element; Family membership
YP_001031836.1	Conserved hypothetical protein
YP_001031837.1	Glycoside transferase, six-hairpin, Glycosyl hydrolase 65 central catalytic domain; Specificity unclear
YP_001031838.1	Specificity unclear
YP_001031839.1	Specificity unclear
YP_001031840.1	Specificity unclear
YP_001031841.1	High confidence in function and specificity
YP_001031842.1	PF02645.5: degV family protein; Family membership
YP_001031843.1	PF00657.10: GDSL-like Lipase/Acylhydrolase; Family membership
YP_001031844.1	High confidence in function and specificity
YP_001031846.1	Histone-like bacterial DNA-binding protein; High confidence in function and specificity
YP_001031847.1	GCN5-related N-acetyltransferase; Family membership
YP_001031848.1	Methylated-DNA--protein-cysteine methyltransferase; High confidence in function and specificity
YP_001031849.1	High confidence in function and specificity
YP_001031850.1	High confidence in function and specificity
YP_001031851.1	Specificity unclear
YP_001031852.1	Specificity unclear
YP_001031853.1	PF04397.5: LytTr DNA-binding domain; Conserved hypothetical protein
YP_001031855.1	Aminotransferase class-V; High confidence in function and specificity
YP_001031856.1	PF00877.9: NLP/P60 domain; Function unclear
YP_001031857.1	Similar to oligopeptide ABC transporter substrate binding proteins; Conserved hypothetical protein
YP_001031858.1	Region start changed from 500979 to 500913 (-66 bases)
YP_001031859.1	High confidence in function and specificity
YP_001031860.1	Metallo-beta-lactamase superfamily; Family membership
YP_001031862.1	functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC
YP_001031863.1	Protein of unknown function DUF1273
YP_001031864.1	Similar to regulatory protein spx
YP_001031865.1	Uncharacterised protein family (UPF0223)
YP_001031866.1	Inositol monophosphatase; High confidence in function and specificity
YP_001031867.1	adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active
YP_001031869.1	Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer
YP_001031870.1	synthesizes RNA primers at the replication forks
YP_001031871.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium
YP_001031872.1	contains sugar isomerase domain PF01380.10; Function unclear
YP_001031873.1	Major Facilitator Superfamily; High confidence in function and specificity
YP_001031878.1	ATPase associated with various cellular activities (AAA); High confidence in function and specificity
YP_001031879.1	Protein of unknown function UPF0074, rrf2_super: rrf2 family protein; Family membership
YP_001031880.1	Glyceraldehyde-3-phosphate dehydrogenase, type I; High confidence in function and specificity
YP_001031882.1	cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+)
YP_001031883.1	hydrolyzes diadenosine polyphosphate
YP_001031884.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion
YP_001031885.1	Bacterial extracellular solute-binding protein, family 3; High confidence in function and specificity
YP_001031886.1	High confidence in function and specificity
YP_001031887.1	CDS
YP_001031888.1	Catalyzes a key regulatory step in fatty acid biosynthesis
YP_001031889.1	involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site
YP_001031890.1	HAD-SF-IIB: HAD-superfamily hydrolase, subfamily IIB; High confidence in function and specificity
YP_001031892.1	decarboxylates 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine.
YP_001031893.1	(Phosphopantothenoylcysteine synthetase) (PPC synthetase); High confidence in function and specificity
YP_001031895.1	ATPase-IIIA_H: plasma-membrane proton-efflux P-type ATPase; High confidence in function and specificity
YP_001031896.1	Conserved hypothetical protein
YP_001031897.1	Integrase core domain; High confidence in function and specificity
YP_001031898.1	transposase helper protein for IS981
YP_001031900.1	Conserved hypothetical protein
YP_001031901.1	contains a dimeric alpha-beta barrel domain
YP_001031902.1	High confidence in function and specificity
YP_001031903.1	catalyzes the formation of thymidine 5'-phosphate from thymidine
YP_001031905.1	recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2
YP_001031907.1	Nitroreductase; Family membership
YP_001031908.1	Protein-glutamine N- methyltransferase; High confidence in function and specificity
YP_001031909.1	GCN5-related N-acetyltransferase, Acetyltransferase (GNAT) family; Family membership
YP_001031910.1	TIGR00057: Sua5/YciO/YrdC/YwlC family protein; Family membership
YP_001031911.1	catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate
YP_001031912.1	Similar to pneumococcal vaccine antigen A; Specificity unclear
YP_001031913.1	catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine
YP_001031914.1	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; High confidence in function and specificity
YP_001031915.1	High confidence in function and specificity
YP_001031916.1	catalyzes the hydrolysis of acylphosphate
YP_001031917.1	23S rRNA (guanosine-2'-O-)-methyltransferase, rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3; High confidence in function and specificity
YP_001031918.1	contains RmlC-like cupin domain; Family membership
YP_001031919.1	HTH-type transcriptional regulator,  DNA binding; Family membership
YP_001031920.1	Similar to inorganic pyrophosphatase; Function unclear
YP_001031921.1	An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
YP_001031922.1	contains Homeodomain-like domain; Family membership
YP_001031923.1	catalyzes the removal of N-terminal amino acids from peptides and arylamides
YP_001031924.1	Ribonuclease BN-like family; Function unclear
YP_001031925.1	GtrA-like protein; Conserved hypothetical protein
YP_001031927.1	catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system
YP_001031928.1	transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein
YP_001031929.1	Bacterial protein of unknown function DUF948, general stress protein
YP_001031931.1	catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate
YP_001031932.1	K+ potassium transporter; Conserved hypothetical protein
YP_001031934.1	Protein of unknown function DUF161, Uncharacterized BCR, YitT family COG1284; Conserved hypothetical protein
YP_001031935.1	IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity
YP_001031936.1	Function unclear
YP_001031937.1	SPFH domain / Band 7 family, Similar to several eukaryotic hypersensitive-induced response proteins; Family membership
YP_001031938.1	DNA breaking-rejoining enzyme, catalytic core, site- specific recombinase, phage integrase; High confidence in function and specificity
YP_001031939.1	Similar to ps202 from IL1403, phage associated
YP_001031941.1	Similar to pi358 from IL1403, Phage associated
YP_001031942.1	phage associated
YP_001031943.1	Region start changed from 586756 to 586684 (72 bases)
YP_001031944.1	Glycosyl transferase, family 2; High confidence in function and specificity
YP_001031946.1	Disruption induces osmosensitive phenotype
YP_001031947.1	Similar to Lactococcus bacteriophage repressor; Function unclear
YP_001031948.1	member of metallo-beta-lactamase; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions
YP_001031949.1	Oxidoreductase, Short-chain dehydrogenase; Family membership
YP_001031950.1	DHH family; High confidence in function and specificity
YP_001031951.1	catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis
YP_001031952.1	participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
YP_001031953.1	TIGR00247: conserved hypothetical protein TIGR00247
YP_001031954.1	necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YP_001031955.1	Family membership
YP_001031956.1	transposase helper protein for IS904
YP_001031957.1	Region start changed from 601339 to 601417 (-78 bases)
YP_001031958.1	Firmicute transcriptional repressor of class III stress genes; High confidence in function and specificity
YP_001031959.1	High confidence in function and specificity
YP_001031960.1	Sigma 54 modulation protein/ribosomal protein S30EA, Similar to yfiA in E. Coli, ribosomal subunit interface protein; Specificity unclear
YP_001031961.1	enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis
YP_001031962.1	DNA breaking-rejoining enzyme, catalytic core, Phage integrase; Conserved hypothetical protein
YP_001031963.1	Also present on plasmid pJW394; Conserved hypothetical protein
YP_001031964.1	Integrase, catalytic region; High confidence in function and specificity
YP_001031965.1	transposase helper protein for IS981
YP_001031966.1	High confidence in function and specificity
YP_001031967.1	Specificity unclear
YP_001031968.1	Protein of unknown function DUF214; Conserved hypothetical protein
YP_001031969.1	Homeodomain-like
YP_001031970.1	Acetyl-coenzyme A synthetase; High confidence in function and specificity
YP_001031971.1	Similar to Mg2+ transporter protein, CorA-like; Specificity unclear
YP_001031972.1	Pyruvate formate-lyase; High confidence in function and specificity
YP_001031973.1	catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis
YP_001031974.1	Major Facilitator Superfamily; High confidence in function and specificity
YP_001031975.1	in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif
YP_001031976.1	rodA_shape: rod shape-determining protein RodA; High confidence in function and specificity
YP_001031977.1	biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate
YP_001031978.1	catalyzes the formation of citrate from acetyl-CoA and oxaloacetate
YP_001031979.1	Catalyzes the conversion of citrate to isocitrate
YP_001031980.1	High confidence in function and specificity
YP_001031981.1	hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates
YP_001031983.1	the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress
YP_001031985.1	Conserved hypothetical protein
YP_001031986.1	Specificity unclear
YP_001031988.1	Conserved hypothetical protein
YP_001031989.1	Glycosyl transferase, family 2; Function unclear
YP_001031990.1	Integrase, catalytic region; High confidence in function and specificity
YP_001031991.1	transposase helper protein for IS981; Family membership
YP_001031992.1	Similar to polysaccharide deacetylase; High confidence in function and specificity
YP_001031993.1	branched-chain amino acid:cation transporter LIVCS family; High confidence in function and specificity
YP_001031994.1	Conserved hypothetical protein
YP_001031995.1	Region start changed from 648046 to 647968 (-78 bases)
YP_001031996.1	transposase helper protein for insertion sequence element IS904
YP_001031997.1	Integrase, catalytic region; High confidence in function and specificity
YP_001031998.1	contains Homeodomain-like region; Family membership
YP_001031999.1	Transposase DDE domain; Family membership
YP_001032000.1	Specificity unclear
YP_001032001.1	Type I restriction modification system, M subunit; Specificity unclear
YP_001032002.1	Type I restriction modification DNA specificity subunit; Specificity unclear
YP_001032003.1	Mg2+ transporter protein, CorA-like; Specificity unclear
YP_001032004.1	catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline
YP_001032005.1	Peptidase M20/M25/M40; High confidence in function and specificity
YP_001032006.1	Major facilitator superfamily; High confidence in function and specificity
YP_001032007.1	GCN5-related N-acetyltransferase; Family membership
YP_001032010.1	TIGR01847: Bacteriocin-type signal sequence
YP_001032013.1	High confidence in function and specificity
YP_001032015.1	GCN5-related N-acetyltransferase, Acetyltransferase (GNAT) family; Family membership
YP_001032018.1	Conserved hypothetical protein
YP_001032020.1	Lambda repressor-like, DNA-binding., Contains Helix- turn-helix domain
YP_001032021.1	Integrase, catalytic region; Specificity unclear
YP_001032022.1	PF01695: IstB-like ATP-binding protein; Function unclear
YP_001032023.1	Integrase, catalytic region; High confidence in function and specificity
YP_001032026.1	Contains bacteriocin-type signal sequence
YP_001032029.1	E1-E2 ATPase; High confidence in function and specificity
YP_001032031.1	Contains Heavy-Metal-Associated (HMA) domain; Specificity unclear
YP_001032032.1	Ferritin/ribonucleotide reductase-like
YP_001032033.1	Cyclic nucleotide-binding domain; Conserved hypothetical protein
YP_001032036.1	High confidence in function and specificity
YP_001032037.1	High confidence in function and specificity
YP_001032038.1	Binding-protein-dependent transport systems inner membrane component; High confidence in function and specificity
YP_001032039.1	Binding-protein-dependent transport systems inner membrane component; High confidence in function and specificity
YP_001032040.1	Bacterial extracellular solute-binding protein, family 5; High confidence in function and specificity
YP_001032041.1	Peptidase M13; High confidence in function and specificity
YP_001032042.1	Transposase DDE domain; Specificity unclear
YP_001032048.1	Family membership
YP_001032049.1	Conserved hypothetical protein
YP_001032050.1	High confidence in function and specificity
YP_001032051.1	Conserved hypothetical protein
YP_001032053.1	Integrase, catalytic region; High confidence in function and specificity
YP_001032056.1	Integrase, catalytic region, also known as iso- ISS1; High confidence in function and specificity
YP_001032057.1	Similar to molybdenum cofactor biosynthesis protein; Conserved hypothetical protein
YP_001032058.1	Similar to peptide ABC-type transporters; Function unclear
YP_001032059.1	transposase helper protein for IS981
YP_001032060.1	Integrase, catalytic region; High confidence in function and specificity
YP_001032061.1	catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_001032062.1	Domain of unknown function (DUF956)
YP_001032063.1	Protein of unknown function DUF161, Uncharacterized BCR, YitT family COG1284
YP_001032064.1	Protein of unknown function DUF956
YP_001032065.1	EIID-AGA: PTS system, mannose/fructose/sorbose family, IID component; High confidence in function and specificity
YP_001032066.1	EII-Sor: PTS system, mannose/fructose/sorbose family, IIC component; High confidence in function and specificity
YP_001032067.1	pts-sorbose: PTS system, mannose/fructose/sorbose family, IIB component; High confidence in function and specificity
YP_001032068.1	3Fe-4S ferredoxin; Conserved hypothetical protein
YP_001032069.1	Contains one Peptidoglycan-binding LysM domain
YP_001032070.1	Catalyzes the formation of (d)CDP from ATP and (d)CMP
YP_001032071.1	lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain; High confidence in function and specificity
YP_001032072.1	Isochorismatase, Similar to amidases related to nicotinamidase; Family membership
YP_001032073.1	Similar to predicted metal-dependent membrane protease; Conserved hypothetical protein
YP_001032074.1	High confidence in function and specificity
YP_001032075.1	High confidence in function and specificity
YP_001032076.1	Maltotriose-binding protein precursor (Maltodextrin- binding protein); High confidence in function and specificity
YP_001032077.1	Cyclomaltodextrinase; High confidence in function and specificity
YP_001032078.1	High confidence in function and specificity
YP_001032079.1	High confidence in function and specificity
YP_001032080.1	High confidence in function and specificity
YP_001032081.1	High confidence in function and specificity
YP_001032082.1	Glycosyl hydrolase 65 central catalytic domain; High confidence in function and specificity
YP_001032083.1	High confidence in function and specificity
YP_001032084.1	Response regulator receiver domain; High confidence in function and specificity
YP_001032085.1	Histidine kinase; High confidence in function and specificity
YP_001032086.1	catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate
YP_001032087.1	Protein of unknown function DUF37
YP_001032088.1	required for arbutin uptake and metabolism
YP_001032089.1	High confidence in function and specificity
YP_001032090.1	High confidence in function and specificity
YP_001032091.1	Transcriptional activator, Rgg/GadR/MutR family; Function unclear
YP_001032095.1	High confidence in function and specificity
YP_001032096.1	catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate
YP_001032097.1	Transglycosylase-like domain; Family membership
YP_001032098.1	oxidoreductase, Gfo/Idh/MocA family; Family membership
YP_001032099.1	functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor
YP_001032100.1	in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta
YP_001032102.1	Cof-subfamily: Cof-like hydrolase; Family membership
YP_001032103.1	FtsK/SpoIIIE family; High confidence in function and specificity
YP_001032105.1	required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA
YP_001032106.1	Family membership
YP_001032107.1	Family membership
YP_001032109.1	Xaa-Pro dipeptidase; High confidence in function and specificity
YP_001032110.1	High confidence in function and specificity
YP_001032111.1	High confidence in function and specificity
YP_001032112.1	Similar to Colicin V production protein; Conserved hypothetical protein
YP_001032113.1	mutS2: MutS2 family protein; High confidence in function and specificity
YP_001032114.1	Contains thioredoxin domain 2; High confidence in function and specificity
YP_001032116.1	catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis
YP_001032117.1	Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide
YP_001032118.1	High confidence in function and specificity
YP_001032119.1	High confidence in function and specificity
YP_001032120.1	cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source
YP_001032121.1	RbsD / FucU transport protein family; High confidence in function and specificity
YP_001032122.1	High confidence in function and specificity
YP_001032123.1	High confidence in function and specificity
YP_001032124.1	PF00589: Phage integrase; High confidence in function and specificity
YP_001032126.1	PF06114: Protein of unknown function DUF955
YP_001032127.1	repressor, IPR010982: Lambda repressor-like, DNA- binding, PF01381: Helix-turn-helix; High confidence in function and specificity
YP_001032129.1	IPR010982: Lambda repressor-like, DNA-binding
YP_001032131.1	antirepressor
YP_001032136.1	PF04761: Lactococcus bacteriophage  transcription regulator
YP_001032137.1	PF07211: Protein of unknown function DUF1417
YP_001032138.1	TIGR01618: phage nucleotide-binding protein; Conserved hypothetical protein
YP_001032139.1	ssDNA binding protein
YP_001032140.1	PF06926:  replisome organiser protein C- terminus; Family membership
YP_001032141.1	DnaC protein
YP_001032143.1	holliday junction resolvase, PF05866: Endodeoxyribonuclease RusA; High confidence in function and specificity
YP_001032144.1	PF06275: Protein of unknown function DUF1031
YP_001032146.1	PF06563: Protein of unknown function DUF1125
YP_001032147.1	PF07852: Protein of unknown function DUF1642
YP_001032148.1	PF00692: dUTPase, TIGR00576: deoxyuridine 5'- triphosphate nucleotidohydrolase (dut); High confidence in function and specificity
YP_001032153.1	PF05263: Protein of unknown function DUF722
YP_001032154.1	PF00665: Integrase core domain; Conserved hypothetical protein
YP_001032155.1	PF01695: IstB-like ATP-binding protein; Conserved hypothetical protein
YP_001032156.1	PF03592: Terminase small subunit; High confidence in function and specificity
YP_001032157.1	TIGR01547: phage terminase, large subunit, PBSX family
YP_001032158.1	PF05133: Phage portal protein, SPP1 Gp6-like, TIGR01538: phage portal protein, SPP1 family; Conserved hypothetical protein
YP_001032159.1	PF04327: Protein of unknown function DUF464; Specificity unclear
YP_001032160.1	TIGR01641 : phage  head morphogenesis protein, SPP1 gp7 family
YP_001032170.1	Conserved hypothetical protein
YP_001032173.1	minor tail protein
YP_001032179.1	PF01183: Glycosyl hydrolases family 25; High confidence in function and specificity
YP_001032180.1	PF07751: Abi-like protein
YP_001032184.1	multidrug transporter PF07690: Major Facilitator Superfamily
YP_001032185.1	Bacterial regulatory proteins, gntR family; High confidence in function and specificity
YP_001032186.1	High confidence in function and specificity
YP_001032187.1	catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate
YP_001032188.1	Major facilitator superfamily MFS_1; High confidence in function and specificity
YP_001032189.1	Galactose mutarotase-like; Function unclear
YP_001032190.1	catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism
YP_001032191.1	catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate
YP_001032192.1	Family membership
YP_001032193.1	High confidence in function and specificity
YP_001032194.1	membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr
YP_001032195.1	catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase
YP_001032197.1	Similar to glycerol uptake facilitator glpF; Function unclear
YP_001032198.1	catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde
YP_001032199.1	contains NUDIX domain; Family membership
YP_001032200.1	contains NUDIX domain; High confidence in function and specificity
YP_001032201.1	catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis
YP_001032202.1	MgtC/SapB family protein; Family membership
YP_001032203.1	Family membership
YP_001032204.1	Similar to Immunoglobulin A1 protease precursor; Conserved hypothetical protein
YP_001032205.1	Signal recognition particle 54 kDa protein 2 (SRP54); High confidence in function and specificity
YP_001032206.1	GCN5-related N-acetyltransferase; High confidence in function and specificity
YP_001032207.1	High confidence in function and specificity
YP_001032208.1	Conserved hypothetical protein
YP_001032209.1	Protein of unknown function DUF931; Conserved hypothetical protein
YP_001032211.1	Protein of unknown function DUF438
YP_001032212.1	catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis
YP_001032213.1	Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway
YP_001032214.1	CDF: cation diffusion facilitator family transporter; Specificity unclear
YP_001032215.1	Function unclear
YP_001032217.1	regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity
YP_001032218.1	High confidence in function and specificity
YP_001032219.1	catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis
YP_001032220.1	catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers
YP_001032222.1	phage gene
YP_001032223.1	Protein of unknown function DUF1535; Conserved hypothetical protein
YP_001032226.1	helper protein for IS981
YP_001032227.1	Integrase, catalytic region; High confidence in function and specificity
YP_001032228.1	Similar to low molecular weight phosphotyrosine protein phosphatases; High confidence in function and specificity
YP_001032229.1	Family membership
YP_001032230.1	contains CHAP domain; Family membership
YP_001032232.1	RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome
YP_001032233.1	Predicted metal-binding, possibly nucleic acid- binding protein, Protein of unknown function DUF177; Conserved hypothetical protein; ORF2
YP_001032234.1	Contains response regulator receiver domain; High confidence in function and specificity
YP_001032235.1	High confidence in function and specificity
YP_001032236.1	High confidence in function and specificity
YP_001032237.1	High confidence in function and specificity
YP_001032238.1	UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation
YP_001032239.1	UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis
YP_001032240.1	High confidence in function and specificity
YP_001032241.1	essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication
YP_001032245.1	Conserved hypothetical protein
YP_001032246.1	Conserved hypothetical protein
YP_001032247.1	Conserved hypothetical protein
YP_001032248.1	Bacterial protein of unknown function DUF916, Similar to cell wall surface anchor family protein
YP_001032249.1	Lambda repressor-like, DNA-binding; Family membership
YP_001032250.1	Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step
YP_001032251.1	Esterase/lipase/thioesterase, conserved secreted hypothetical protein; possible alpha/beta hydrolase; Family membership
YP_001032252.1	Glucosamine-6-phosphate deaminase; High confidence in function and specificity
YP_001032253.1	High confidence in function and specificity
YP_001032254.1	High confidence in function and specificity
YP_001032255.1	High confidence in function and specificity
YP_001032256.1	binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity
YP_001032257.1	contains KH domain (SSF54814)
YP_001032258.1	protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic
YP_001032259.1	contains Alpha/beta hydrolase fold; High confidence in function and specificity
YP_001032260.1	Essential for efficient processing of 16S rRNA
YP_001032261.1	methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA
YP_001032262.1	Protein of unknown function DUF1149
YP_001032263.1	degV family protein
YP_001032264.1	catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis
YP_001032265.1	GCN5-related N-acetyltransferase; Family membership
YP_001032266.1	catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity
YP_001032267.1	High confidence in function and specificity
YP_001032268.1	Conserved hypothetical protein
YP_001032269.1	High confidence in function and specificity
YP_001032270.1	probable metCcysK operon transcriptional activator; Conserved hypothetical protein
YP_001032271.1	Uup: ATPase components of ABC transporters with duplicated ATPase domains
YP_001032272.1	Family membership
YP_001032273.1	High confidence in function and specificity
YP_001032274.1	catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; subclass 1A is a dimer formed by two identical PyrD subunits each containing an FMN group
YP_001032275.1	Protein of unknown function DUF1113; Conserved hypothetical protein
YP_001032277.1	PF00107.12: Zinc-containing alcohol dehydrogenase superfamily; High confidence in function and specificity
YP_001032278.1	Function unclear
YP_001032279.1	High confidence in function and specificity
YP_001032280.1	catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity
YP_001032281.1	Specificity unclear
YP_001032282.1	High confidence in function and specificity
YP_001032283.1	ROK_glcA_fam: ROK family protein ( glucokinase); High confidence in function and specificity
YP_001032284.1	Function unclear
YP_001032285.1	Similar to lactose/cellobiose PTS system IIC components; Specificity unclear
YP_001032286.1	ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived
YP_001032288.1	High confidence in function and specificity
YP_001032289.1	Major facilitator superfamily; Family membership
YP_001032290.1	High confidence in function and specificity
YP_001032292.1	Family membership
YP_001032293.1	Contains dimeric alpha-beta barrel region
YP_001032294.1	SSF51182: RmlC-like cupin
YP_001032295.1	catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase
YP_001032296.1	High confidence in function and specificity
YP_001032297.1	catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis
YP_001032298.1	catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis
YP_001032299.1	Catalyzes first step of the de novo purine nucleotide biosynthetic pathway
YP_001032301.1	Conserved hypothetical protein
YP_001032302.1	Conserved hypothetical protein
YP_001032303.1	transposase helper protein for IS904
YP_001032304.1	Conserved hypothetical protein
YP_001032305.1	Similar to first 37 aa of L.lactis IL1403 protein ypgH
YP_001032306.1	phage protein; Conserved hypothetical protein
YP_001032307.1	High confidence in function and specificity
YP_001032308.1	catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis
YP_001032309.1	glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate
YP_001032310.1	Family membership
YP_001032311.1	Family membership
YP_001032312.1	Family membership
YP_001032313.1	PF00156.12: Phosphoribosyltransferase; High confidence in function and specificity
YP_001032314.1	involved in de novo purine biosynthesis
YP_001032315.1	HAD-superfamily subfamily IA hydrolase; Family membership
YP_001032316.1	Family membership
YP_001032317.1	catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis
YP_001032318.1	TIGR01484: HAD-superfamily hydrolase, subfamily IIB; Family membership
YP_001032319.1	High confidence in function and specificity
YP_001032320.1	With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway
YP_001032321.1	Conserved hypothetical protein
YP_001032322.1	High confidence in function and specificity
YP_001032323.1	Integrase, catalytic region; High confidence in function and specificity
YP_001032324.1	Specificity unclear
YP_001032325.1	ROK_glcA_fam: ROK family protein ( glucokinase); Function unclear
YP_001032326.1	High confidence in function and specificity
YP_001032328.1	contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway
YP_001032329.1	High confidence in function and specificity
YP_001032330.1	Conserved hypothetical protein
YP_001032331.1	High confidence in function and specificity
YP_001032332.1	Specificity unclear
YP_001032334.1	Contains Proteinase inhibitor I11 ecotin domain (SSF49772)
YP_001032335.1	Similar to multi antimicrobial extrusion protein MatE; Conserved hypothetical protein
YP_001032336.1	Similar to CorA-like Mg2+ transporter proteins; Family membership
YP_001032337.1	High confidence in function and specificity
YP_001032338.1	Function unclear
YP_001032339.1	High confidence in function and specificity
YP_001032340.1	Protein of unknown function DUF6; Conserved hypothetical protein
YP_001032341.1	High confidence in function and specificity
YP_001032342.1	Integral membrane protein DUF125; Conserved hypothetical protein
YP_001032343.1	Protein of unknown function DUF125
YP_001032344.1	Family membership
YP_001032345.1	Bacterial regulatory protein, MarR family; Family membership
YP_001032346.1	Family membership
YP_001032347.1	Protein of unknown function DUF1304; Conserved hypothetical protein
YP_001032348.1	with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine
YP_001032349.1	TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity
YP_001032350.1	Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate
YP_001032353.1	PF00903.12: Glyoxalase/bleomycin resistance protein/dioxygenase; Specificity unclear
YP_001032354.1	involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water
YP_001032355.1	High confidence in function and specificity
YP_001032357.1	catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate
YP_001032358.1	catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis
YP_001032359.1	High confidence in function and specificity
YP_001032360.1	High confidence in function and specificity
YP_001032361.1	repressor of the osmoprotectant uptake system; High confidence in function and specificity
YP_001032362.1	High confidence in function and specificity
YP_001032363.1	Conserved hypothetical protein
YP_001032368.1	Similar to ParB-like nucleases
YP_001032369.1	Lambda repressor-like, DNA-binding; Conserved hypothetical protein
YP_001032370.1	CDF: cation diffusion facilitator family transporter; Conserved hypothetical protein
YP_001032371.1	Phosphate-starvation-inducible E; Specificity unclear
YP_001032372.1	catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis
YP_001032373.1	High confidence in function and specificity
YP_001032374.1	Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway
YP_001032376.1	catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate
YP_001032377.1	High confidence in function and specificity
YP_001032378.1	Conserved hypothetical protein
YP_001032379.1	High confidence in function and specificity
YP_001032381.1	High confidence in function and specificity
YP_001032382.1	Response regulator receiver domain; High confidence in function and specificity
YP_001032383.1	PF04297:  helix-turn-helix protein, YlxM/p13-like
YP_001032384.1	Similar to prophage gene p301 from L.lactis IL1403; Conserved hypothetical protein
YP_001032385.1	High confidence in function and specificity
YP_001032386.1	transposase helper protein for IS904
YP_001032387.1	Integrase, catalytic region, 30 aa from the C- terminus are missing, possibly inactive; High confidence in function and specificity
YP_001032388.1	PF01695: IstB-like ATP-binding protein; Conserved hypothetical protein
YP_001032389.1	Integrase, catalytic region; Specificity unclear
YP_001032390.1	GCN5-related N-acetyltransferase; Family membership
YP_001032391.1	Family membership
YP_001032393.1	Protein of unknown function DUF1093
YP_001032394.1	Specificity unclear
YP_001032395.1	Protein of unknown function DUF1304; Conserved hypothetical protein
YP_001032396.1	Conserved hypothetical protein
YP_001032397.1	Protein of unknown function DUF1211; Conserved hypothetical protein
YP_001032398.1	Conserved hypothetical protein
YP_001032399.1	Protein of unknown function DUF208
YP_001032400.1	Specificity unclear
YP_001032401.1	High confidence in function and specificity
YP_001032402.1	High confidence in function and specificity
YP_001032403.1	four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity
YP_001032407.1	Bacterial protein of unknown function DUF916; Conserved hypothetical protein
YP_001032410.1	Bacterial protein of unknown function DUF916
YP_001032411.1	High confidence in function and specificity
YP_001032412.1	High confidence in function and specificity
YP_001032413.1	Converts glycerol and ADP to glycerol-3-phosphate and ADP
YP_001032414.1	High confidence in function and specificity
YP_001032415.1	Protein of unknown function DUF477; Conserved hypothetical protein
YP_001032417.1	Conserved hypothetical protein
YP_001032418.1	Family membership
YP_001032419.1	Phthalate dioxygenase reductase; High confidence in function and specificity
YP_001032420.1	catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits, similar to the PyrDA subunits and two PyrK subunits
YP_001032421.1	type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase
YP_001032422.1	Conserved hypothetical protein
YP_001032423.1	glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA
YP_001032424.1	High confidence in function and specificity
YP_001032425.1	High confidence in function and specificity
YP_001032426.1	Protein of unknown function DUF1312
YP_001032427.1	High confidence in function and specificity
YP_001032428.1	catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate
YP_001032429.1	Similar to Bacillus subtilis xpaC gene, involved in cell morphology; Specificity unclear
YP_001032430.1	High confidence in function and specificity
YP_001032431.1	High confidence in function and specificity
YP_001032432.1	catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis
YP_001032433.1	catalyzes the formation of phosphoenolpyruvate from pyruvate
YP_001032434.1	Converts (S)-lactate and NAD(+) to pyruvate and NADH
YP_001032435.1	High confidence in function and specificity
YP_001032436.1	High confidence in function and specificity
YP_001032437.1	High confidence in function and specificity
YP_001032438.1	Similar to rRNA (guanine-N1-)-methyltransferase; Family membership
YP_001032439.1	Family membership
YP_001032440.1	Conserved hypothetical protein
YP_001032441.1	Carboxypeptidase regulatory region; Conserved hypothetical protein
YP_001032442.1	Carboxypeptidase regulatory region
YP_001032443.1	Surface protein from Gram-positive cocci, anchor region
YP_001032444.1	Arsenate reductase and related, Similar to regulatory protein spx
YP_001032445.1	ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis
YP_001032446.1	TIGR00619: nuclease SbcCD, D subunit; High confidence in function and specificity
YP_001032447.1	ATP-dependent dsDNA exonuclease; High confidence in function and specificity
YP_001032450.1	PF00005: ABC transporter TIGR01166: cobalt transport protein ATP-binding subunit; High confidence in function and specificity
YP_001032451.1	PF00950: ABC 3 transport family; Conserved hypothetical protein
YP_001032452.1	PF01297: Periplasmic solute binding protein family; Family membership
YP_001032455.1	contains HTH domain; Conserved hypothetical protein
YP_001032456.1	High confidence in function and specificity
YP_001032457.1	inactivated by IS981, HTH-type transcriptional regulator, PF01381: Helix-turn-helix
YP_001032458.1	High confidence in function and specificity
YP_001032459.1	transposase helper protein for IS981
YP_001032460.1	inactivated by IS981, HTH-type transcriptional regulator
YP_001032461.1	contains HTH domain; Conserved hypothetical protein
YP_001032463.1	PF02423: Ornithine cyclodeaminase/mu-crystallin family; High confidence in function and specificity
YP_001032464.1	phenazine biosynthesis protein, PF02567: Phenazine biosynthesis-like protein, TIGR00654: phenazine biosynthesis protein PhzF family
YP_001032465.1	transcriptional regulator, PF00392: Bacterial regulatory proteins, GntR family
YP_001032466.1	PF07523: Bacterial Ig-like domain (group 3)
YP_001032467.1	PF00117: Glutamine amidotransferase class-I, TIGR00566: glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase; High confidence in function and specificity
YP_001032468.1	PF00425: chorismate binding enzyme, TIGR00553: para- aminobenzoate synthase, component I; High confidence in function and specificity
YP_001032469.1	potential redox protein; structural similarity to proteins involved in arsenate reduction in the oxydoreduction reaction, Arsenate reductase and related, PF03960: ArsC family; Conserved hypothetical protein
YP_001032470.1	repressor of arsenical resistance, PF06953: Arsenical resistance operon trans-acting repressor ArsD
YP_001032471.1	Pseudogene
YP_001032472.1	Pseudogene
YP_001032474.1	Pseudogene; Conserved hypothetical protein
YP_001032475.1	Pseudogene; Conserved hypothetical protein
YP_001032476.1	IPR006059: Bacterial extracellular solute-binding protein, family 1; Conserved hypothetical protein
YP_001032477.1	sugar ABC transporter permease, IPR000515: Binding-protein-dependent transport systems inner membrane component; Conserved hypothetical protein
YP_001032478.1	sugar ABC transporter permease, PF00528: Binding-protein-dependent transport system inner membrane component; Conserved hypothetical protein
YP_001032479.1	pseudogene, IPR008928: Glycoside transferase, six- hairpin; High confidence in function and specificity
YP_001032480.1	pseudogene, IPR008928: Glycoside transferase, six- hairpin; Conserved hypothetical protein
YP_001032481.1	PF01522: Polysaccharide deacetylase; High confidence in function and specificity
YP_001032482.1	PF07488: Glycosyl hydrolase 67 middle domain, PF07477: Glycosyl hydrolase 67 C-terminus; High confidence in function and specificity
YP_001032483.1	IPR004843: Metallophosphoesterase
YP_001032485.1	PF00455: Bacterial regulatory proteins, deoR family; Conserved hypothetical protein
YP_001032486.1	membrane protein
YP_001032488.1	essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc)
YP_001032489.1	RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids
YP_001032490.1	activates chloride dependent transcription of gadCB, TIGR01716: Transcriptional activator Rgg/GadR/MutR, C-terminal domain; High confidence in function and specificity
YP_001032491.1	TIGR00910: Glutamate:g-aminobutyrate antiporter, involved in glutamate-dependent acid resistance; High confidence in function and specificity
YP_001032492.1	PF00282: Pyridoxal-dependent decarboxylase conserved domain, TIGR01788: glutamate decarboxylase, involved in glutamate-dependant acid resistance; High confidence in function and specificity
YP_001032493.1	mechanosensitive ion channel, PF00924: Mechanosensitive ion channel
YP_001032494.1	catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids
YP_001032495.1	IPR011004: Trimeric LpxA-like; Conserved hypothetical protein
YP_001032496.1	PF01645: Conserved region in glutamate synthase; High confidence in function and specificity
YP_001032497.1	glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate
YP_001032498.1	PF00278: Pyridoxal-dependent decarboxylase, C- terminal sheet domain, TIGR01048: diaminopimelate decarboxylase; High confidence in function and specificity
YP_001032499.1	PF03672: Protein of unknown function UPF0154
YP_001032500.1	converts L-glutamate to D-glutamate, a component of peptidoglycan
YP_001032501.1	Ham1-like protein, PF01725: Ham1 family, TIGR00042: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; High confidence in function and specificity
YP_001032502.1	TIGR00040: phosphodiesterase, MJ0936 family, PF00149: Calcineurin-like phosphoesterase
YP_001032503.1	PF00571: 2 CBS domains
YP_001032504.1	site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs
YP_001032505.1	functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB
YP_001032506.1	functions during chromosome segregation; may form a condensin-like structure with SMC and ScpA; forms a homodimer
YP_001032507.1	PF00849: RNA pseudouridylate synthase; High confidence in function and specificity
YP_001032508.1	membrane protein
YP_001032509.1	secreted protein
YP_001032510.1	membrane protein
YP_001032511.1	secreted protein
YP_001032513.1	Pseudogene
YP_001032514.1	PF00005: ABC transporter TIGR02203: lipid A export ATP-binding/permease MsbA; Conserved hypothetical protein
YP_001032515.1	PF00664: ABC transporter transmembrane region, PF00005: ABC transporter TIGR02203: lipid A export ATP- binding/permease MsbA; Conserved hypothetical protein
YP_001032516.1	IPR011056: Peptidase S24 and S26, C-terminal region, PF01381: Helix-turn-helix; Conserved hypothetical protein
YP_001032517.1	membrane protein
YP_001032518.1	binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit
YP_001032519.1	present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors
YP_001032520.1	PF01047: MarR family; Conserved hypothetical protein
YP_001032521.1	PF07690: Major facilitator superfamily, TIGR00711: drug resistance transporter EmrB/QacA subfamily; Conserved hypothetical protein
YP_001032523.1	pseudogene,  glycosyl transferase
YP_001032524.1	Pseudogene,  glycosyl transferase, PF00535: glycosyl transferase, family 2
YP_001032525.1	catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP
YP_001032526.1	TIGR00097 : phosphomethylpyrimidine kinase; High confidence in function and specificity
YP_001032527.1	PF02581: Thiamine monophosphate synthase/TENI, TIGR00693: thiamine-phosphate pyrophosphorylase; High confidence in function and specificity
YP_001032528.1	transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid
YP_001032529.1	PF03062: Membrane bound O-acyl transferase, MBOAT; Conserved hypothetical protein
YP_001032530.1	D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid
YP_001032531.1	PF04918: DltD central region; High confidence in function and specificity
YP_001032532.1	PF00122: E1-E2 ATPase, PF00690: Cation transporter/ATPase, N-terminus; High confidence in function and specificity
YP_001032533.1	PF01325: Iron dependent repressor, N-terminal DNA binding domain; Conserved hypothetical protein
YP_001032534.1	catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine
YP_001032535.1	PF02219: Methylenetetrahydrofolate reductase, TIGR00676: 5,10-methylenetetrahydrofolate reductase; High confidence in function and specificity
YP_001032536.1	catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive
YP_001032537.1	Region start changed from 1200064 to 1200025 (-39 bases)
YP_001032539.1	membrane protein
YP_001032540.1	Conserved hypothetical protein
YP_001032541.1	transposase helper protein for IS904
YP_001032542.1	PF00665: Integrase core domain; High confidence in function and specificity
YP_001032543.1	transposase helper protein for IS981
YP_001032544.1	PF00027: Cyclic nucleotide-binding domain; Conserved hypothetical protein
YP_001032545.1	membrane protein
YP_001032546.1	High confidence in function and specificity
YP_001032547.1	PF00313: 'Cold-shock' DNA-binding domain; Conserved hypothetical protein
YP_001032548.1	PF01380: Sugar isomerase (SIS)
YP_001032549.1	pseudogene
YP_001032550.1	pseudogene
YP_001032551.1	endoglucanase, IPR008928: Glycoside transferase, six-hairpin; High confidence in function and specificity
YP_001032553.1	hydrolase, haloacid dehalogenase-like family, TIGR00099: Cof-like hydrolase
YP_001032554.1	High confidence in function and specificity
YP_001032555.1	PF06953: Arsenical resistance operon trans-acting repressor ArsD; Conserved hypothetical protein
YP_001032556.1	PF02374: Anion-transporting ATPase, TIGR00345: arsenite-activated ATPase; High confidence in function and specificity
YP_001032557.1	pyridine nucleotide-disulphide oxidoreductase, PF00070: Pyridine nucleotide-disulphide oxidoreductase
YP_001032558.1	PF01758: Sodium Bile acid symporter family, TIGR00832: arsenical-resistance protein; Conserved hypothetical protein
YP_001032560.1	transcriptional regulator, IPR009061:  DNA binding
YP_001032561.1	aldo/keto reductase, PF00248: Aldo/keto reductase
YP_001032563.1	IPR008994: Nucleic acid-binding OB-fold, PF00313: 'Cold-shock' DNA-binding domain; Conserved hypothetical protein
YP_001032564.1	PF00313: Cold-shock protein, DNA-binding; Conserved hypothetical protein
YP_001032565.1	membrane protein, PF04226: Transglycosylase-associated protein
YP_001032566.1	membrane protein
YP_001032567.1	membrane protein
YP_001032568.1	pseudogene,  general stress protein, PF03780: Protein of unknown function DUF322
YP_001032569.1	PF01695: IstB-like ATP-binding protein; Conserved hypothetical protein
YP_001032570.1	PF00665: Integrase core domain; Conserved hypothetical protein
YP_001032571.1	pseudogene,  general stress protein, PF03780: Protein of unknown function DUF322
YP_001032572.1	Conserved hypothetical protein
YP_001032573.1	Conserved hypothetical protein
YP_001032575.1	site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerS
YP_001032577.1	site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerS
YP_001032578.1	TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine
YP_001032579.1	catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity
YP_001032580.1	PF02481: SMF family, TIGR00732: DNA processing protein DprA, Conserved hypothetical protein
YP_001032581.1	translation initiation inhibitor, PF01042: Endoribonuclease L-PSP, TIGR00004: endoribonuclease L-PSP, Conserved hypothetical protein
YP_001032582.1	PF03306: Alpha-acetolactate decarboxylase, TIGR01252: alpha-acetolactate decarboxylase; High confidence in function and specificity
YP_001032583.1	catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic
YP_001032584.1	catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis
YP_001032585.1	with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit
YP_001032586.1	catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit
YP_001032587.1	catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis
YP_001032588.1	PF00005: ABC transporter; Conserved hypothetical protein
YP_001032589.1	catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D
YP_001032590.1	membrane protein
YP_001032591.1	dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate
YP_001032592.1	PF00581: Rhodanese-like domain
YP_001032593.1	IPR010140: Histidinol phosphate phosphatase, HisJ, TIGR01856: histidinol phosphate phosphatase HisJ family; High confidence in function and specificity
YP_001032594.1	catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis
YP_001032595.1	catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase
YP_001032596.1	catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide
YP_001032597.1	with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide
YP_001032598.1	kanamycin kinase , PF01636: Phosphotransferase enzyme family
YP_001032599.1	catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis
YP_001032600.1	PF00815: Histidinol dehydrogenase, TIGR00069: histidinol dehydrogenase; High confidence in function and specificity
YP_001032601.1	short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ
YP_001032602.1	IPR006195: Aminoacyl-transfer RNA synthetase, class II; High confidence in function and specificity
YP_001032603.1	catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis
YP_001032604.1	pseudogene,  membrane protein, PF06966: Protein of unknown function DUF1295
YP_001032605.1	pseudogene,  membrane protein, PF06966: Protein of unknown function DUF1295
YP_001032606.1	PF02645: DegV, PF02734: DAK2 domain
YP_001032607.1	membrane protein
YP_001032608.1	sensory protein, PF03073: TspO/MBR family
YP_001032609.1	PF00773: RNB-like protein, TIGR02063: ribonuclease R; High confidence in function and specificity
YP_001032610.1	PF01381: Helix-turn-helix
YP_001032611.1	adhesin precursor, IPR008985: Concanavalin A-like lectin/glucanase, PF05738: Cna protein B-type domain
YP_001032613.1	catalyzes the formation of 2-acetolactate from pyruvate in stationary phase
YP_001032614.1	TPR domain protein
YP_001032615.1	membrane protein, PF01594: Domain of unknown function DUF20
YP_001032616.1	methyltransferase
YP_001032618.1	TIGR00479: 23S rRNA (uracil-5-)-methyltransferase RumA, PF05958: tRNA (Uracil-5-)-methyltransferase , PF01938: TRAM domain; Conserved hypothetical protein
YP_001032619.1	PF01380: Sugar isomerase (SIS), PF01418: Helix-turn- helix domain, rpiR family; Conserved hypothetical protein
YP_001032620.1	Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate
YP_001032621.1	PF00122: E1-E2 ATPase, TIGR01647: plasma-membrane proton-efflux P-type ATPase; High confidence in function and specificity
YP_001032622.1	PF00872: Transposase, Mutator family; High confidence in function and specificity
YP_001032623.1	pseudogene; Conserved hypothetical protein
YP_001032624.1	Endoglucanase
YP_001032625.1	multidrug efflux permease , PF07690: Major facilitator superfamily
YP_001032626.1	PF00872: Transposase, Mutator family; High confidence in function and specificity
YP_001032627.1	pseudogene, PF00165: Bacterial regulatory helix- turn-helix proteins, AraC type; Conserved hypothetical protein
YP_001032628.1	Spermidine/putrescine ABC transporter substrate binding; High confidence in function and specificity
YP_001032629.1	High confidence in function and specificity
YP_001032630.1	High confidence in function and specificity
YP_001032631.1	High confidence in function and specificity
YP_001032632.1	catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis
YP_001032633.1	Conserved hypothetical protein
YP_001032634.1	catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate
YP_001032635.1	catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine
YP_001032636.1	High confidence in function and specificity
YP_001032638.1	Also known as ylgG (AAN64308), IPR000086: NUDIX_hydrolase domain (NUcleoside DIphosphate linked to some other moiety X)
YP_001032639.1	High confidence in function and specificity
YP_001032641.1	High confidence in function and specificity
YP_001032642.1	binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential
YP_001032643.1	binds and unfolds substrates as part of the ClpXP protease
YP_001032644.1	High confidence in function and specificity
YP_001032647.1	High confidence in function and specificity
YP_001032648.1	Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine
YP_001032649.1	ORF59; transcriptional regulator, IPR010982: Lambda repressor-like, DNA-binding, PF01381: Helix-turn- helix
YP_001032650.1	ORF58
YP_001032651.1	ORF57; integral membrane protein, PF04332: Protein of unknown function DUF475
YP_001032652.1	PF02342: Bacterial stress protein; Conserved hypothetical protein
YP_001032653.1	PF02342: Bacterial stress protein; Conserved hypothetical protein
YP_001032654.1	PF02342: Bacterial stress protein; Conserved hypothetical protein
YP_001032655.1	ORF53; PF05816: Toxic anion resistance protein (TelA)
YP_001032656.1	ORF52
YP_001032657.1	ORF51
YP_001032658.1	ORF50
YP_001032659.1	ORF49
YP_001032660.1	ORF48
YP_001032661.1	ORF47; transcriptional regulator, IPR010982: Lambda repressor-like, DNA-binding, PF01381: Helix-turn- helix
YP_001032662.1	ORF46
YP_001032663.1	site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerS
YP_001032664.1	ORF44
YP_001032665.1	ORF43
YP_001032666.1	ORF42
YP_001032667.1	ORF41
YP_001032668.1	High confidence in function and specificity
YP_001032669.1	ORF39
YP_001032670.1	ORF38
YP_001032671.1	Mobilisation protein
YP_001032673.1	ORF34; IPR008687: Bacterial mobilisation
YP_001032674.1	DNA topoisomerase, IPR000380: DNA topoisomerase I; High confidence in function and specificity
YP_001032676.1	Conserved hypothetical protein
YP_001032677.1	ORF30
YP_001032678.1	ORF29
YP_001032679.1	ORF28; Conserved hypothetical protein
YP_001032680.1	ORF27
YP_001032681.1	ORF26
YP_001032682.1	PF02534: TraG/TraD family; Conserved hypothetical protein
YP_001032683.1	ORF24
YP_001032684.1	ORF23
YP_001032685.1	ORF22; Conserved hypothetical protein
YP_001032686.1	ORF21; Specificity unclear
YP_001032687.1	ORF20; membrane protein
YP_001032688.1	ORF19
YP_001032689.1	ORF18
YP_001032690.1	Region start changed from 1367033 to 1366889 (-144 bases)
YP_001032691.1	ORF16
YP_001032692.1	ORF15
YP_001032693.1	ORF14
YP_001032694.1	ORF13
YP_001032695.1	ORF12
YP_001032696.1	Bacterial adhesion involved in high frequency conjugation,  peptidoglycan linked, gram positive LPXTG cell wall anchor, signal peptide; High confidence in function and specificity
YP_001032697.1	ORF10
YP_001032698.1	ORF9; PF00226: DnaJ domain
YP_001032699.1	ORF8
YP_001032700.1	ORF7
YP_001032701.1	ORF6
YP_001032702.1	ORF5
YP_001032703.1	ORF4
YP_001032704.1	ORF3
YP_001032705.1	ORF2
YP_001032706.1	ORF1
YP_001032707.1	High confidence in function and specificity
YP_001032708.1	Protein of unknown function DUF1461; Family membership
YP_001032709.1	phosphatases involved in N-acetyl- glucosamine catabolism, TIGR01457: HAD-SF-IIA-hyp2: HAD- superfamily subfamily IIA hydrolase; High confidence in function and specificity
YP_001032710.1	Acyl-ACP thioesterase,  oleoyl- acyl carrier protein thioesterase
YP_001032712.1	autolytic lysozyme; Conserved hypothetical protein
YP_001032713.1	catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III
YP_001032714.1	Conserved hypothetical protein
YP_001032717.1	PF02275.7: Linear amide C-N hydrolases, choloylglycine hydrolase; High confidence in function and specificity
YP_001032718.1	Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate
YP_001032719.1	PF01380.10: Contains sugar isomerase (SIS) domain., PF01418.7: Helix-turn-helix protein RpiR; Conserved hypothetical protein
YP_001032720.1	High confidence in function and specificity
YP_001032721.1	catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway
YP_001032722.1	Bacterial protein of unknown function DUF871
YP_001032723.1	High confidence in function and specificity
YP_001032724.1	catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities
YP_001032725.1	catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs
YP_001032727.1	PF00478: IMP dehydrogenase / GMP reductase domain; Conserved hypothetical protein
YP_001032728.1	Conserved hypothetical protein
YP_001032730.1	Integrase, catalytic region; High confidence in function and specificity
YP_001032731.1	transposase helper protein for IS981
YP_001032732.1	Protein kinase-like; Family membership
YP_001032733.1	Reduces fumarate to succinate in anaerobic bacterial respiration
YP_001032734.1	Family membership
YP_001032735.1	contains NUDIX domain; High confidence in function and specificity
YP_001032736.1	High confidence in function and specificity
YP_001032738.1	Conserved hypothetical protein
YP_001032739.1	C-terminal end; Specificity unclear
YP_001032740.1	High confidence in function and specificity
YP_001032741.1	High confidence in function and specificity
YP_001032742.1	negatively supercoils closed circular double-stranded DNA
YP_001032743.1	Contains Amino acid permease-associated region; Function unclear
YP_001032744.1	Similar to nucleoside-diphosphate-sugar epimerases; Conserved hypothetical protein
YP_001032745.1	ROK_glcA_fam: ROK family protein ( glucokinase), Similar to xylose repressor protein; Specificity unclear
YP_001032746.1	Glycoside hydrolase, family 1; High confidence in function and specificity
YP_001032747.1	Glycoside hydrolase, family 3; High confidence in function and specificity
YP_001032748.1	oligo_HPY: oligopeptide/dipeptide ABC transporter ATP-binding protein; Specificity unclear
YP_001032749.1	Specificity unclear
YP_001032750.1	Specificity unclear
YP_001032751.1	Specificity unclear
YP_001032752.1	Specificity unclear
YP_001032753.1	Contains sugar isomerase (SIS)domain; Family membership
YP_001032754.1	binds to the ribosome on the universally-conserved alpha-sarcin loop
YP_001032755.1	High confidence in function and specificity
YP_001032756.1	High confidence in function and specificity
YP_001032757.1	CobB/CobQ-like glutamine amidotransferase; High confidence in function and specificity
YP_001032758.1	Similar to ABC-type antimicrobial peptide transport system, permease component; Specificity unclear
YP_001032759.1	Specificity unclear
YP_001032760.1	catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers
YP_001032761.1	GCN5-related N-acetyltransferase; Family membership
YP_001032762.1	catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate
YP_001032763.1	transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria
YP_001032764.1	Cl- channel, voltage gated, Voltage gated chloride channel; Specificity unclear
YP_001032765.1	Bacterial protein of unknown function DUF896
YP_001032766.1	glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA
YP_001032767.1	glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA
YP_001032768.1	High confidence in function and specificity
YP_001032769.1	Protein of unknown function DUF475; Conserved hypothetical protein
YP_001032770.1	VanZ like protein; Function unclear
YP_001032771.1	Protein of unknown function UPF0029
YP_001032772.1	DEAD/DEAH box helicase, N-terminal, competence protein; Function unclear
YP_001032773.1	comF: comF family protein, Similar to amidophosphoribosyltransferases; Function unclear
YP_001032774.1	Bacterial protein of unknown function DUF925
YP_001032775.1	High confidence in function and specificity
YP_001032776.1	Protein of unknown function UPF0054
YP_001032777.1	contains NUDIX domain; Family membership
YP_001032778.1	phosphate starvation inducible protein; High confidence in function and specificity
YP_001032779.1	nramp: NRAMP family Mn2+/Fe2+ transporters; High confidence in function and specificity
YP_001032780.1	involved in the peptidyltransferase reaction during translation
YP_001032781.1	Protein of unknown function DUF464
YP_001032782.1	High confidence in function and specificity
YP_001032783.1	Conserved hypothetical protein
YP_001032785.1	metal-dependent phosphohydrolase, contains HD region; Family membership
YP_001032786.1	Cof-subfamily: Cof-like hydrolase; Family membership
YP_001032788.1	NIF3 (NGG1p interacting factor 3) like protein
YP_001032789.1	Similar to SAM-dependent methyltransferases; Conserved hypothetical protein
YP_001032790.1	HhH-GPD superfamily base excision DNA repair protein; High confidence in function and specificity
YP_001032791.1	DnaD-like domain; High confidence in function and specificity
YP_001032792.1	TIGR02167: Bacterial surface protein 26-residue repeat; Family membership
YP_001032795.1	SSF49313: cadherin, PF07523.2: Bacterial Ig-like, SSF50447: Translation factor, TIGR01167: Surface protein from Gram-positive cocci, anchor region
YP_001032796.1	SM00671: Sel1-like repeat, contains HTH motif; Family membership
YP_001032797.1	catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis
YP_001032798.1	involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate
YP_001032799.1	Function unclear
YP_001032800.1	arsC_related: conserved hypothetical protein, Similar to Regulatory protein spx
YP_001032801.1	modulates transcription in response to the NADH/NAD(+) redox state
YP_001032802.1	Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase
YP_001032803.1	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
YP_001032805.1	High confidence in function and specificity
YP_001032806.1	Conserved hypothetical protein
YP_001032807.1	Response regulator receiver domain; High confidence in function and specificity
YP_001032808.1	Family membership
YP_001032809.1	Conserved hypothetical protein
YP_001032810.1	Similar to acid phosphatase/vanadium-dependent haloperoxidases
YP_001032811.1	High confidence in function and specificity
YP_001032812.1	lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis
YP_001032814.1	Family membership
YP_001032816.1	RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not
YP_001032817.1	3,4-dihydroxy-2-butanone 4-phosphate synthase, GTP cyclohydrolase II; High confidence in function and specificity
YP_001032818.1	catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine
YP_001032820.1	Mg2+ and Co2+ transporter protein, CorA-like; Conserved hypothetical protein
YP_001032821.1	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling
YP_001032822.1	GCN5-related N-acetyltransferase; Conserved hypothetical protein
YP_001032823.1	High confidence in function and specificity
YP_001032824.1	High confidence in function and specificity
YP_001032825.1	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling
YP_001032826.1	involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX
YP_001032827.1	High confidence in function and specificity
YP_001032828.1	in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF
YP_001032829.1	Catalyzes the rate-limiting step in dNTP synthesis
YP_001032830.1	B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE
YP_001032831.1	High confidence in function and specificity
YP_001032832.1	High confidence in function and specificity
YP_001032833.1	recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1
YP_001032834.1	Family membership
YP_001032836.1	Protein of unknown function DUF402
YP_001032837.1	High confidence in function and specificity
YP_001032838.1	Specificity unclear
YP_001032839.1	Specificity unclear
YP_001032840.1	Homeodomain-like; Family membership
YP_001032841.1	Protein of unknown function DUF199
YP_001032842.1	Conserved hypothetical protein CofD related, Uncharacterised protein family UPF0052
YP_001032843.1	Uncharacterised P-loop ATPase UPF0042; Family membership
YP_001032844.1	High confidence in function and specificity
YP_001032845.1	Cyclic nucleotide-binding domain; High confidence in function and specificity
YP_001032846.1	Ferritin/ribonucleotide reductase-like; Conserved hypothetical protein
YP_001032847.1	High confidence in function and specificity
YP_001032849.1	Protein of unknown function DUF805; Conserved hypothetical protein
YP_001032850.1	transposase helper protein for IS904; High confidence in function and specificity
YP_001032851.1	Integrase, catalytic region; High confidence in function and specificity
YP_001032852.1	High confidence in function and specificity
YP_001032853.1	High confidence in function and specificity
YP_001032854.1	High confidence in function and specificity
YP_001032855.1	Bacterial regulatory proteins, deoR family; High confidence in function and specificity
YP_001032856.1	High confidence in function and specificity
YP_001032857.1	in group A Streptococci this protein was found to cross react with anti myosin antibodies and may play a role in rheumatic fever
YP_001032858.1	Hypothetical 70.0 kDa protein in dnaK 3'region
YP_001032859.1	heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria
YP_001032860.1	with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor
YP_001032861.1	Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
YP_001032863.1	High confidence in function and specificity
YP_001032864.1	High confidence in function and specificity
YP_001032866.1	Protein of unknown function DUF711
YP_001032867.1	ACT domain-containing protein
YP_001032868.1	Specificity unclear
YP_001032869.1	Family membership
YP_001032870.1	Similar to amidases related to nicotinamidase; Family membership
YP_001032871.1	exoribonuclease, VacB/Rnb family; High confidence in function and specificity
YP_001032872.1	Preprotein translocase SecG subunit; High confidence in function and specificity
YP_001032873.1	High confidence in function and specificity
YP_001032875.1	Specificity unclear
YP_001032876.1	Specificity unclear
YP_001032877.1	Specificity unclear
YP_001032878.1	Region start changed from 1568256 to 1568289 (33 bases)
YP_001032879.1	catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate
YP_001032880.1	Protein of unknown function DUF74
YP_001032881.1	Protein of unknown function DUF984
YP_001032883.1	catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate
YP_001032885.1	catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose
YP_001032886.1	Similar to cell envelope-related transcriptional attenuator lytR; Conserved hypothetical protein
YP_001032888.1	CDP-glycerol:glycerophosphate glycerophosphotransferase; High confidence in function and specificity
YP_001032890.1	High confidence in function and specificity
YP_001032892.1	Similar to xylosidases/arabinosidases; Function unclear
YP_001032893.1	Similar to lipolytic enzymes, G-D-S-L family; Family membership
YP_001032894.1	Integrase, catalytic region; Specificity unclear
YP_001032895.1	PF01695: IstB-like ATP-binding protein; Specificity unclear
YP_001032898.1	Family membership
YP_001032899.1	High confidence in function and specificity
YP_001032900.1	glycosyl transferase, group 2 family protein, Glycosyltransferases involved in cell wall biogenesis; Family membership
YP_001032903.1	glycosyl transferase, group 2 family protein, Glycosyltransferases involved in cell wall biogenesis; Family membership
YP_001032904.1	glycosyl transferase, group 2 family protein, Glycosyltransferases involved in cell wall biogenesi; Family membership
YP_001032905.1	High confidence in function and specificity
YP_001032906.1	High confidence in function and specificity
YP_001032907.1	High confidence in function and specificity
YP_001032908.1	Conserved hypothetical protein
YP_001032909.1	Specificity unclear
YP_001032910.1	Conserved hypothetical protein
YP_001032911.1	methyltransferase, UbiE/COQ5 family; Family membership
YP_001032913.1	negatively supercoils closed circular double-stranded DNA
YP_001032914.1	Haloacid dehalogenase-like hydrolase; High confidence in function and specificity
YP_001032915.1	Similar to predicted ring-cleavage extradiol dioxygenase; Family membership
YP_001032916.1	Similar to ABC type transport system permease; Conserved hypothetical protein
YP_001032917.1	Specificity unclear
YP_001032918.1	TIGRFAM 2A78: Carboxylate/Amino Acid/Amine Transporter; Conserved hypothetical protein
YP_001032919.1	High confidence in function and specificity
YP_001032920.1	malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate
YP_001032921.1	Similar to  lincosamides and streptogramins A transporter Lsa; Specificity unclear
YP_001032923.1	High confidence in function and specificity
YP_001032924.1	High confidence in function and specificity
YP_001032925.1	Cell cycle protein; High confidence in function and specificity
YP_001032926.1	Conserved hypothetical protein
YP_001032927.1	polyribonucleotide nucleotidyltransferase, 30S ribosomal protein S1; Function unclear
YP_001032928.1	High confidence in function and specificity
YP_001032929.1	Cof-subfamily: Cof-like hydrolase, Peptidyl-prolyl cis-trans isomerase, cyclophilin type; Family membership
YP_001032930.1	Response regulator receiver domain; High confidence in function and specificity
YP_001032931.1	Histidine kinase; High confidence in function and specificity
YP_001032932.1	Region start changed from 1627838 to 1627784 (-54 bases)
YP_001032934.1	Similar to predicted ring-cleavage extradiol dioxygenases
YP_001032935.1	PF05257.3: CHAP domain
YP_001032936.1	Integrase, catalytic region; High confidence in function and specificity
YP_001032937.1	transposase helper protein for IS981; High confidence in function and specificity
YP_001032939.1	Similar to phage integrases; High confidence in function and specificity
YP_001032940.1	metal-sulfur cluster biosynthetic enzyme
YP_001032941.1	Similar to phage infection protein pip
YP_001032942.1	Family membership
YP_001032943.1	Histone-like bacterial DNA-binding protein; High confidence in function and specificity
YP_001032944.1	Universal stress protein family; High confidence in function and specificity
YP_001032946.1	High confidence in function and specificity
YP_001032948.1	Conserved hypothetical protein
YP_001032949.1	Glycosyl transferase, family 2, Glycosyltransferases, probably involved in cell wall biogenesis; Specificity unclear
YP_001032951.1	GCN5-related N-acetyltransferase
YP_001032952.1	Conserved hypothetical protein
YP_001032953.1	this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
YP_001032954.1	Similar to GTP pyrophosphokinases; High confidence in function and specificity
YP_001032955.1	High confidence in function and specificity
YP_001032956.1	Specificity unclear
YP_001032957.1	Protein of unknown function DUF214; Function unclear
YP_001032959.1	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YP_001032960.1	High confidence in function and specificity
YP_001032961.1	Conserved hypothetical protein
YP_001032962.1	High confidence in function and specificity
YP_001032963.1	Protein of unknown function DUF805; Conserved hypothetical protein
YP_001032964.1	Protein of unknown function DUF805; Conserved hypothetical protein
YP_001032965.1	Protein of unknown function DUF1211; Conserved hypothetical protein
YP_001032966.1	Recombination protein N; High confidence in function and specificity
YP_001032967.1	High confidence in function and specificity
YP_001032968.1	Similar to tly, Hemolysin A, Similar to rRNA methylases
YP_001032969.1	GCN5-related N-acetyltransferase; Family membership
YP_001032971.1	catalyzes the bidirectional exonucleolytic cleavage of DNA
YP_001032972.1	bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides
YP_001032973.1	catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate
YP_001032974.1	High confidence in function and specificity
YP_001032977.1	High confidence in function and specificity
YP_001032978.1	High confidence in function and specificity
YP_001032980.1	High confidence in function and specificity
YP_001032981.1	Similar to regulatory protein spx; Family membership
YP_001032982.1	converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer
YP_001032983.1	Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids
YP_001032984.1	divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases
YP_001032985.1	Conserved hypothetical protein
YP_001032986.1	Similar to Lipopolysaccharide 1,2- glucosyltransferases; Family membership
YP_001032987.1	High confidence in function and specificity
YP_001032988.1	Glycosyltransferases involved in cell wall biogenesis; Family membership
YP_001032989.1	Integrase, catalytic region; High confidence in function and specificity
YP_001032990.1	transposase helper protein for IS981; Specificity unclear
YP_001032991.1	transposase helper protein for IS904
YP_001032992.1	Integrase, catalytic region; High confidence in function and specificity
YP_001032993.1	High confidence in function and specificity
YP_001032994.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
YP_001032995.1	High confidence in function and specificity
YP_001032996.1	High confidence in function and specificity
YP_001032997.1	Conserved hypothetical protein
YP_001032998.1	in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins
YP_001032999.1	catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs
YP_001033000.1	High confidence in function and specificity
YP_001033001.1	Conserved hypothetical protein
YP_001033003.1	High confidence in function and specificity
YP_001033004.1	TIGR00003: copper ion binding protein; High confidence in function and specificity
YP_001033005.1	High confidence in function and specificity
YP_001033006.1	High confidence in function and specificity
YP_001033007.1	High confidence in function and specificity
YP_001033008.1	High confidence in function and specificity
YP_001033009.1	High confidence in function and specificity
YP_001033011.1	High confidence in function and specificity
YP_001033012.1	High confidence in function and specificity
YP_001033013.1	LacI-family regulatory protein; Family membership
YP_001033014.1	leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase
YP_001033015.1	contains Fis-type Helix-turn-helix domain; Conserved hypothetical protein
YP_001033016.1	catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP
YP_001033017.1	High confidence in function and specificity
YP_001033019.1	Cof-subfamily: Cof-like hydrolase; Conserved hypothetical protein
YP_001033020.1	Family membership
YP_001033021.1	Conserved hypothetical protein
YP_001033022.1	Conserved hypothetical protein
YP_001033024.1	Conserved hypothetical protein
YP_001033025.1	High confidence in function and specificity
YP_001033026.1	cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity
YP_001033027.1	catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway
YP_001033028.1	catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate
YP_001033029.1	High confidence in function and specificity
YP_001033030.1	bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate
YP_001033031.1	catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate
YP_001033032.1	Family membership
YP_001033033.1	Protein of unknown function DUF988
YP_001033035.1	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
YP_001033037.1	High confidence in function and specificity
YP_001033038.1	exodeoxyribonuclease A; High confidence in function and specificity
YP_001033039.1	GCN5-related N-acetyltransferase; High confidence in function and specificity
YP_001033040.1	High confidence in function and specificity
YP_001033041.1	Similar to regulatory protein spx; Family membership
YP_001033042.1	Protein of unknown function DUF156
YP_001033043.1	High confidence in function and specificity
YP_001033044.1	Contains rhodanese-like domain; Conserved hypothetical protein
YP_001033045.1	Contains Rhodanese-like domain; Conserved hypothetical protein
YP_001033046.1	CsbD-like protein
YP_001033048.1	cysteine synthase; High confidence in function and specificity
YP_001033049.1	catalyzes the formation of L-cystathionine from O-succinyl-L-homoserine and L-cysteine; or Cystathionine beta-lyase (CBL) can convert cystathionine to homocysteine
YP_001033050.1	High confidence in function and specificity
YP_001033051.1	catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits
YP_001033052.1	an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
YP_001033054.1	in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP
YP_001033055.1	composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism
YP_001033056.1	High confidence in function and specificity
YP_001033057.1	catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
YP_001033058.1	High confidence in function and specificity
YP_001033059.1	carries the fatty acid chain in fatty acid biosynthesis
YP_001033060.1	FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs
YP_001033061.1	High confidence in function and specificity
YP_001033062.1	High confidence in function and specificity
YP_001033064.1	associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock
YP_001033065.1	Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
YP_001033066.1	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; Conserved hypothetical protein
YP_001033067.1	Protein of unknown function DUF448., Predicted nucleic-acid-binding protein implicated in transcription termination
YP_001033068.1	modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination
YP_001033069.1	in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins
YP_001033070.1	export of murein hydrolases; Conserved hypothetical protein
YP_001033071.1	effector of murein hydrolase; Conserved hypothetical protein
YP_001033072.1	Conserved hypothetical protein
YP_001033073.1	High confidence in function and specificity
YP_001033074.1	Contains Cna B-type domain (PF05738.2)
YP_001033075.1	Surface protein from Gram-positive cocci, anchor region; Family membership
YP_001033076.1	Transcriptional regulator Rgg/GadR/MutR family; Family membership
YP_001033077.1	EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains
YP_001033078.1	Region start changed from 1788440 to 1788272 (-168 bases)
YP_001033079.1	Family membership
YP_001033080.1	Primosomal protein that may act to load helicase DnaC during DNA replication
YP_001033081.1	High confidence in function and specificity
YP_001033082.1	Protein of unknown function DUF193, Contains ATP- cone domain PF03477; Conserved hypothetical protein
YP_001033083.1	tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine
YP_001033084.1	Phosphotransferase enzyme family, Similar to choline kinases involved in LPS biosynthesis
YP_001033085.1	Protein of unknown function DUF1021
YP_001033086.1	High confidence in function and specificity
YP_001033087.1	in Escherichia coli this protein is wrapped around the base of the L1 stalk
YP_001033088.1	Phosphoesterase, RecJ-like, DHH family; Conserved hypothetical protein
YP_001033089.1	Family membership
YP_001033090.1	High confidence in function and specificity
YP_001033091.1	patatin like protein
YP_001033092.1	catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive
YP_001033093.1	Similar to C terminal of FloL, flotilin like protein
YP_001033094.1	Cof-subfamily: Cof-like hydrolase
YP_001033095.1	High confidence in function and specificity
YP_001033097.1	PF01368.8: Phosphoesterase, RecJ-like, PF02272.6: Phosphoesterase, DHHA1
YP_001033098.1	PF00571.15: contains CBS domain; Family membership
YP_001033099.1	GCN5-related N-acetyltransferase; Family membership
YP_001033100.1	High confidence in function and specificity
YP_001033102.1	contains alpha/beta hydrolase fold; High confidence in function and specificity
YP_001033103.1	catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA
YP_001033104.1	High confidence in function and specificity
YP_001033105.1	High confidence in function and specificity
YP_001033106.1	Phenylacetic acid degradation-related protein
YP_001033107.1	transcriptional regulator, LacI family; High confidence in function and specificity
YP_001033108.1	Glycoside hydrolase, family 31; High confidence in function and specificity
YP_001033109.1	Protein of unknown function DUF624; Family membership
YP_001033110.1	Family membership
YP_001033111.1	Family membership
YP_001033112.1	Integrase, catalytic region; High confidence in function and specificity
YP_001033113.1	transposase helper protein for IS981
YP_001033114.1	SSF56349: DNA breaking-rejoining enzyme, catalytic core, fragment
YP_001033115.1	cytidine/deoxycytidylate deaminase
YP_001033116.1	PF00149.13: Metallophosphoesterase
YP_001033117.1	PF00753.14: Beta-lactamase-like; Family membership
YP_001033118.1	Cold-shock protein, DNA-binding, 'Cold-shock' DNA- binding domain; Conserved hypothetical protein
YP_001033119.1	Nucleic acid-binding OB-fold, 'Cold-shock' DNA- binding domain; Conserved hypothetical protein
YP_001033121.1	High confidence in function and specificity
YP_001033122.1	Zinc-containing alcohol dehydrogenase superfamily; High confidence in function and specificity
YP_001033123.1	Protein of unknown function DUF1275; Conserved hypothetical protein
YP_001033124.1	SSF53056: Carbonic anhydrase, prokaryotic and plant
YP_001033125.1	Protein of unknown function DUF214; Family membership
YP_001033126.1	PF00597.8: DedA family protein; High confidence in function and specificity
YP_001033128.1	High confidence in function and specificity
YP_001033129.1	Conserved hypothetical protein
YP_001033130.1	Conserved hypothetical protein
YP_001033131.1	High confidence in function and specificity
YP_001033132.1	involved in the cytochrome D branch of aerobic respiration; High confidence in function and specificity
YP_001033133.1	involved in the cytochrome D branch of aerobic respiration; High confidence in function and specificity
YP_001033134.1	High confidence in function and specificity
YP_001033135.1	High confidence in function and specificity
YP_001033136.1	POT family protein; High confidence in function and specificity
YP_001033137.1	Conserved hypothetical protein
YP_001033138.1	contains Bacteriocin-type signal sequence
YP_001033139.1	Family membership
YP_001033142.1	PF00343.8: Glycosyl transferase, family 35, P_ylase: glycogen/starch/alpha-glucan phosphorylases; High confidence in function and specificity
YP_001033143.1	catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose
YP_001033144.1	High confidence in function and specificity
YP_001033145.1	catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate
YP_001033146.1	N utilization substance protein B homolog (NusB protein); High confidence in function and specificity
YP_001033147.1	Protein of unknown function DUF322
YP_001033148.1	Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA
YP_001033149.1	metallopeptidase M24; High confidence in function and specificity
YP_001033150.1	catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin
YP_001033151.1	primaseG_like: primase-related protein, TIGR00334; High confidence in function and specificity
YP_001033152.1	COG0563: Adenylate kinase and related kinases [Enterococcus faecium]
YP_001033153.1	TatD-related deoxyribonuclease, TIGR00010: hydrolase, TatD family; High confidence in function and specificity
YP_001033154.1	DNA breaking-rejoining enzyme, catalytic core; Conserved hypothetical protein
YP_001033155.1	N-terminal 10aa extension to Tn5276 excisionase in L. lactis reported in database.[alternative start point (ttg)]
YP_001033156.1	Conserved hypothetical protein
YP_001033158.1	CHAP family similarity although does not contain the invariant Cys,His residues
YP_001033159.1	Conserved hypothetical protein
YP_001033160.1	Similar to phosphoglycerate/bisphosphoglycerate mutases; High confidence in function and specificity
YP_001033161.1	Conserved hypothetical protein
YP_001033162.1	ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation
YP_001033163.1	ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation
YP_001033164.1	Conserved hypothetical protein
YP_001033165.1	Conserved hypothetical protein
YP_001033166.1	Conserved hypothetical protein
YP_001033167.1	Conserved hypothetical protein
YP_001033168.1	binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation
YP_001033169.1	Protein of unknown function DUF24; Conserved hypothetical protein
YP_001033170.1	Similar to NAD(P)H nitroreductases; High confidence in function and specificity
YP_001033171.1	GDSL-like Lipase/Acylhydrolase; High confidence in function and specificity
YP_001033172.1	Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_001033173.1	High confidence in function and specificity
YP_001033174.1	O-methyltransferase, family 3; High confidence in function and specificity
YP_001033175.1	Peptidase M3B, oligoendopeptidase F; High confidence in function and specificity
YP_001033176.1	Protein of unknown function DUF218
YP_001033177.1	COG:4814 Uncharacterized protein with an alpha/beta hydrolase fold, Bacterial protein of unknown function DUF915
YP_001033178.1	Xanthine/uracil/vitamin C permease; Conserved hypothetical protein
YP_001033179.1	Cof-subfamily: Cof-like hydrolase TIGRFAM00099; Conserved hypothetical protein
YP_001033181.1	Similar to  electron transport protein ykgF (E. coli), TIGR00273: iron-sulfur cluster binding protein; Conserved hypothetical protein
YP_001033182.1	Protein of unknown function DUF162, Uncharacterized ACR, YkgG family COG1556; Conserved hypothetical protein
YP_001033183.1	Protein of unknown function UPF0005; Conserved hypothetical protein
YP_001033184.1	Conserved hypothetical protein, similarity to eucaryotic, Diacylglycerol kinase (catalytic domain)
YP_001033185.1	Metal-dependent phosphohydrolase, HD region
YP_001033186.1	binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase
YP_001033187.1	RecD/TraA family; High confidence in function and specificity
YP_001033188.1	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; High confidence in function and specificity
YP_001033189.1	catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis
YP_001033191.1	catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis
YP_001033192.1	catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate
YP_001033193.1	Histidine kinase; High confidence in function and specificity
YP_001033194.1	Response regulator; Conserved hypothetical protein
YP_001033195.1	VanZ like family
YP_001033196.1	Sulfate/thiosulfate import ATP-binding protein cysA. ABC transporter related; High confidence in function and specificity
YP_001033197.1	Conserved hypothetical protein
YP_001033198.1	catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis
YP_001033199.1	Protein of unknown function DUF1054
YP_001033200.1	Protein of unknown function DUF606
YP_001033201.1	catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis
YP_001033202.1	AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate
YP_001033203.1	DedA family
YP_001033204.1	glutamine ABC transporter permease and substrate binding protein; High confidence in function and specificity
YP_001033205.1	High confidence in function and specificity
YP_001033207.1	part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane
YP_001033208.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit
YP_001033209.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit
YP_001033210.1	produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit
YP_001033211.1	Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex
YP_001033212.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.
YP_001033213.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0
YP_001033214.1	produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0
YP_001033215.1	esterase; High confidence in function and specificity
YP_001033216.1	Competence protein ComEA helix-hairpin-helix region; High confidence in function and specificity
YP_001033217.1	ABC transporter permease; Conserved hypothetical protein
YP_001033218.1	ABC transporter ATP binding protein; High confidence in function and specificity
YP_001033220.1	Phosphinothricin N-acetyltransferase (GNAT) family; High confidence in function and specificity
YP_001033221.1	cation transporter; Conserved hypothetical protein
YP_001033222.1	TENA/THI-4 protein; High confidence in function and specificity
YP_001033223.1	CHY zinc finger; Conserved hypothetical protein
YP_001033224.1	Biotin-- [acetyl-CoA-carboxylase] synthetase; High confidence in function and specificity
YP_001033225.1	BioY protein; Conserved hypothetical protein
YP_001033226.1	Acetyl-coenzyme A synthetase; High confidence in function and specificity
YP_001033229.1	Conserved hypothetical protein
YP_001033230.1	FeS assembly protein SufB
YP_001033231.1	May be involved in the formation or repair of [Fe- S] clusters present in iron-sulfur proteins
YP_001033233.1	cysteine desulfurases, SufS subfamily; High confidence in function and specificity
YP_001033234.1	FeS assembly protein SufD
YP_001033235.1	ATP-dependent transporter; Conserved hypothetical protein
YP_001033237.1	Phospho-N-acetylmuramoyl-pentapeptide-transferase. Glycosyl transferase; High confidence in function and specificity
YP_001033238.1	Similar to B. subtilis MecA,(Negative regulator of genetic competence in B. subtilis); High confidence in function and specificity
YP_001033239.1	Glutamate ABC transporter ATP binding protein; Conserved hypothetical protein
YP_001033240.1	amino acid ABC transporter permease; High confidence in function and specificity
YP_001033241.1	Diacylglycerol kinase catalytic domain
YP_001033242.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter
YP_001033243.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme
YP_001033244.1	transcriptional repressor, CodY family; High confidence in function and specificity
YP_001033245.1	Family membership
YP_001033246.1	Peptidase M13; High confidence in function and specificity
YP_001033247.1	methylated-DNA--protein-cysteine methyltransferase; High confidence in function and specificity
YP_001033248.1	Polysaccharide biosynthesis protein
YP_001033249.1	involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate
YP_001033250.1	SSF47413: Lambda repressor-like, DNA-binding
YP_001033251.1	similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs
YP_001033252.1	ATP-requiring DNA helicase RecQ; High confidence in function and specificity
YP_001033253.1	Amino acid permease-associated region; High confidence in function and specificity
YP_001033254.1	catalyzes the release of the N-terminal amino acid from a tripeptide
YP_001033256.1	catalyzes the hydrolysis of pyrophosphate to phosphate
YP_001033257.1	Pyruvate formate-lyase 1 activating enzyme; High confidence in function and specificity
YP_001033258.1	Protein of unknown function DUF21
YP_001033259.1	Protein of unknown function DUF20; Conserved hypothetical protein
YP_001033260.1	Protein of unknown function
YP_001033261.1	High confidence in function and specificity
YP_001033262.1	probable acetyltransferase (GNAT) family
YP_001033264.1	zimilar to prophage pi3 protein 58
YP_001033265.1	Uracil-DNA glycosylase superfamily; Conserved hypothetical protein
YP_001033266.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YP_001033269.1	Family membership
YP_001033270.1	Oxidoreductase, Oxidoreductase, NAD- binding Rossmann fold
YP_001033271.1	PF04263.5: Thiamin pyrophosphokinase, catalytic region, PF04265: Thiamin pyrophosphokinase, vitamin B1 binding domain; High confidence in function and specificity
YP_001033272.1	pyrophosphohydrolase, MazG-related, GP37 type
YP_001033275.1	catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_001033277.1	catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate
YP_001033279.1	DnaQ exonuclease/DinG family helicase; High confidence in function and specificity
YP_001033281.1	UspA Universal stress protein family; High confidence in function and specificity
YP_001033282.1	Bacterial extracellular solute-binding protein; High confidence in function and specificity
YP_001033283.1	Binding-protein-dependent transport systems inner membrane component; High confidence in function and specificity
YP_001033284.1	Binding-protein-dependent transport systems inner membrane component; High confidence in function and specificity
YP_001033285.1	binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit
YP_001033286.1	Ribosomal protein L35; Conserved hypothetical protein
YP_001033287.1	IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits
YP_001033290.1	Haloacid dehalogenase-like hydrolase, HAD superfamily
YP_001033291.1	GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs
YP_001033293.1	Protein of unknown function DUF1033
YP_001033294.1	Uncharacterised conserved protein; Conserved hypothetical protein
YP_001033295.1	catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA
YP_001033296.1	Protein of unknown function DUF1211
YP_001033297.1	serine O-acetyltransferase; High confidence in function and specificity
YP_001033299.1	Polyribonucleotide nucleotidyltransferase; High confidence in function and specificity
YP_001033300.1	phosphoribosylpyrophosphate synthetase
YP_001033301.1	catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP
YP_001033302.1	UspA Universal stress protein family; Conserved hypothetical protein
YP_001033303.1	Cysteine desulfurase/Cysteine sulfinate desulfinase; High confidence in function and specificity
YP_001033305.1	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu
YP_001033308.1	IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase type 1 subfamily; some organisms carry two different copies of this enzyme
YP_001033310.1	cell division initiation protein, DivIVA
YP_001033312.1	Protein of unknown function,YGGT protein family, predicted integral membrane protein
YP_001033313.1	Protein of unknown function DUF552; Conserved hypothetical protein
YP_001033314.1	Protein of unknown function UPF0001, conserved hypothetical protein
YP_001033315.1	GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function
YP_001033316.1	Cell division protein FtsA; High confidence in function and specificity
YP_001033317.1	Uncharacterized protein, DegV family COG1307; Conserved hypothetical protein
YP_001033318.1	23S ribosomal RNA methyltransferase, TrmH family; High confidence in function and specificity
YP_001033319.1	Oxidoreductase, Glycine/D-amino acid oxidase; High confidence in function and specificity
YP_001033320.1	Aldo/keto reductase; Family membership
YP_001033321.1	Multidrug resistance protein B, permease of the Major facilitator superfamily, EmrB family; High confidence in function and specificity
YP_001033322.1	HTH type transcriptional regulator, LysR family; Conserved hypothetical protein
YP_001033323.1	HTH-type transcriptional regulator, MerR family; High confidence in function and specificity
YP_001033325.1	Hypothetical protein in pepC 5'region (ORF 2, Metal- dependent phosphohydrolase, HD domain; High confidence in function and specificity
YP_001033328.1	enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine
YP_001033330.1	ADP-ribose pyrophosphatase, MutT/nudix family; High confidence in function and specificity
YP_001033331.1	forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis
YP_001033332.1	catalyzes the formation of L-proline from pyrroline-5-carboxylate
YP_001033333.1	primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence
YP_001033335.1	Protein phosphatase 2C-like; High confidence in function and specificity
YP_001033336.1	Ribosomal RNA small subunit methyltransferase B, NusB/NOL1/NOP2/sun family; High confidence in function and specificity
YP_001033337.1	phage lysin, cell wall hydrolase; High confidence in function and specificity
YP_001033338.1	Phage holin, LL-H; High confidence in function and specificity
YP_001033341.1	Phage minor structural protein, N-terminal, probable phage host specificity protein; High confidence in function and specificity
YP_001033342.1	phage tail component protein; High confidence in function and specificity
YP_001033343.1	tail protein
YP_001033344.1	phage tail component; High confidence in function and specificity
YP_001033345.1	phage tail component; High confidence in function and specificity
YP_001033346.1	Phage major tail protein; High confidence in function and specificity
YP_001033347.1	tail component protein
YP_001033348.1	Bacteriophage protein of unknown function DUF646
YP_001033350.1	Uncharacterized phage protein (possible DNA packaging)
YP_001033351.1	Phage major capsid protein, HK97 phage capsid family; High confidence in function and specificity
YP_001033352.1	Similar to ATP-dependent Clp protease proteolytic subunit; High confidence in function and specificity
YP_001033353.1	Phage portal protein, HK97 family; High confidence in function and specificity
YP_001033354.1	Conserved hypothetical protein
YP_001033355.1	Phage Terminase, large subunit; Conserved hypothetical protein
YP_001033356.1	phage terminase, small subunit, P27 family
YP_001033357.1	restriction endonuclease
YP_001033359.1	Protein of unknown function DUF722
YP_001033360.1	Lambda repressor-like,  DNA-binding protein
YP_001033363.1	PF01695: IstB-like ATP-binding protein; Conserved hypothetical protein
YP_001033364.1	Conserved hypothetical protein
YP_001033367.1	Protein of unknown function DUF1140
YP_001033368.1	Deoxyuridine 5'-triphosphate nucleotidohydrolase; High confidence in function and specificity
YP_001033369.1	Protein of unknown function (DUF1642)
YP_001033376.1	Protein of unknown function DUF1031
YP_001033377.1	Protein of unknown function DUF1064
YP_001033378.1	phage replication module protein; High confidence in function and specificity
YP_001033379.1	replisome organiser; High confidence in function and specificity
YP_001033380.1	Single-strand binding protein (SSB) (Helix- destabilizing protein); High confidence in function and specificity
YP_001033381.1	C-terminal end of prophage protein. Frameshift upstream in N-terminal region (1st 123aa's) corresponding to next ORF automatically called
YP_001033385.1	Conserved hypothetical protein
YP_001033387.1	DNA binding protein
YP_001033388.1	Phage antirepressor protein; Conserved hypothetical protein
YP_001033389.1	Lambda repressor-like, DNA-binding, Helix-turn- helix motif, phage associated
YP_001033390.1	phage associated
YP_001033391.1	phage associated
YP_001033392.1	phage associated
YP_001033393.1	DNA-binding transcriptional regulator, Phage associated; High confidence in function and specificity
YP_001033394.1	phage associated
YP_001033395.1	Phage associated
YP_001033396.1	Phage integrase; High confidence in function and specificity
YP_001033397.1	Protein of unknown function DUF322, Protein of unknown function (DUF322); Conserved hypothetical protein
YP_001033399.1	--
YP_001033400.1	-
YP_001033401.1	modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth
YP_001033402.1	3-demethylubiquinone-9 3-methyltransferase
YP_001033403.1	NUDIX hydrolase; Conserved hypothetical protein
YP_001033405.1	Conserved hypothetical protein
YP_001033406.1	Conserved hypothetical protein
YP_001033407.1	binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity
YP_001033408.1	Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
YP_001033409.1	Essential for recycling GMP and indirectly, cGMP
YP_001033410.1	protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP
YP_001033411.1	Glucosamine-6-phosphate deaminase; High confidence in function and specificity
YP_001033412.1	duplication of the C-terminal end of metK
YP_001033413.1	duplication of the C-terminal end of metK
YP_001033414.1	catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase
YP_001033416.1	BirA bifunctional protein; High confidence in function and specificity
YP_001033417.1	contains PspC domain
YP_001033419.1	peptidoglycan hydrolase; High confidence in function and specificity
YP_001033420.1	catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate
YP_001033421.1	Protein of unknown function; Conserved hypothetical protein
YP_001033422.1	catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr)
YP_001033423.1	High confidence in function and specificity
YP_001033424.1	High confidence in function and specificity
YP_001033425.1	Conserved hypothetical protein
YP_001033426.1	Conserved hypothetical protein
YP_001033427.1	Conserved hypothetical protein
YP_001033428.1	Function unclear
YP_001033429.1	Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate
YP_001033430.1	Sodium/hydrogen exchanger family; High confidence in function and specificity
YP_001033431.1	catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine
YP_001033432.1	catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis
YP_001033435.1	Galactose mutarotase-like, Aldose 1-epimerase
YP_001033436.1	Metal-dependent phosphohydrolase, HD subdomain; Conserved hypothetical protein
YP_001033437.1	Protein of unknown function DUF195, RmuC family
YP_001033439.1	Conserved hypothetical protein
YP_001033440.1	Ribulose-phosphate 3-epimerase; High confidence in function and specificity
YP_001033443.1	EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity
YP_001033444.1	Region start changed from 2159382 to 2159322 (-60 bases)
YP_001033445.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily
YP_001033446.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily
YP_001033447.1	Probable phenolic acid decarboxylase; High confidence in function and specificity
YP_001033448.1	Transcriptional regulator PadR-like
YP_001033449.1	Chitinase II, Glycosyl hydrolases family 18; Conserved hypothetical protein
YP_001033450.1	Chitin-binding, domain 3
YP_001033451.1	catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis
YP_001033453.1	cadmium resistance transporter family protein
YP_001033454.1	becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers
YP_001033455.1	Bacterial bifunctional deaminase-reductase, C- terminal
YP_001033459.1	Dihydrouridine synthase TIM-barrel protein nifR3; Conserved hypothetical protein
YP_001033462.1	Protein of unknown function DUF161
YP_001033463.1	Protein of unknown function DUF161
YP_001033464.1	Protein of unknown function DUF161
YP_001033465.1	catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes
YP_001033466.1	Hypothetical 12.4 kDa HIT-like protein in PSBAII 5'region (ORF 1); High confidence in function and specificity
YP_001033467.1	catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG
YP_001033468.1	Transcriptional activator Rgg/GadR/MutR, C- terminal
YP_001033469.1	Region start changed from 2184026 to 2184023 (-3 bases)
YP_001033470.1	Region start changed from 2184420 to 2184165 (-255 bases)
YP_001033471.1	Region start changed from 2184947 to 2184896 (-51 bases)
YP_001033472.1	Region start changed from 2185332 to 2185329 (-3 bases)
YP_001033474.1	High confidence in function and specificity
YP_001033475.1	Lambda repressor-like, DNA-binding
YP_001033476.1	High confidence in function and specificity
YP_001033477.1	High confidence in function and specificity
YP_001033478.1	RNA-binding S4
YP_001033479.1	Required for DNA replication; binds preferentially to single-stranded, linear DNA
YP_001033480.1	Carboxymuconolactone decarboxylase; High confidence in function and specificity
YP_001033481.1	DNA binding; Conserved hypothetical protein
YP_001033482.1	Bacterial protein of unknown function (DUF915)
YP_001033483.1	NAD dependent epimerase/dehydratase; High confidence in function and specificity
YP_001033484.1	catalyzes the formation of alpha-D-glucose 1-phosphate and UDP-galactose from UDP-glucose and alpha-D-galactose 1-phosphate in galactose metabolism
YP_001033485.1	catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism
YP_001033486.1	Galactose mutarotase-like; High confidence in function and specificity
YP_001033487.1	Sodium:galactoside symporter; Conserved hypothetical protein
YP_001033488.1	transcriptional regulator, PF01380: Sugar isomerase (SIS domain)
YP_001033489.1	IPR006417 Nicotinamide-nucleotide adenylyltransferase, TIGR01526: nicotinamide-nucleotide adenylyltransferase, no DNA binding HTH-motif; Conserved hypothetical protein
YP_001033490.1	PF02826: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; Family membership
YP_001033491.1	PF01136: Peptidase U32,  protease
YP_001033492.1	PF01136: Peptidase U32,  protease
YP_001033494.1	Conserved hypothetical protein
YP_001033496.1	Hypothetical phage protein
YP_001033498.1	PF03592: Terminase small subunit; Conserved hypothetical protein
YP_001033500.1	Conserved hypothetical protein
YP_001033510.1	bacteriophage repressor, PF01381: Helix- turn-helix , IPR010982: Lambda repressor-like, DNA- binding
YP_001033516.1	PF00589: Phage integrase; Conserved hypothetical protein
YP_001033517.1	PF03932: CutC family; Conserved hypothetical protein
YP_001033518.1	PF05975: Bacterial ABC transporter protein EcsB; Family membership
YP_001033519.1	PF00005: ABC transporter; Conserved hypothetical protein
YP_001033520.1	IPR004129: Glycerophosphoryl diester phosphodiesterase , Glycerophosphoryl diester phosphodiesterase
YP_001033521.1	Histidine triad protein, PF01230: HIT domain
YP_001033523.1	membrane protein
YP_001033524.1	in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA
YP_001033525.1	binds directly to 23S ribosomal RNA
YP_001033526.1	membrane protein
YP_001033527.1	PF00005: ABC transporter; Conserved hypothetical protein
YP_001033528.1	PF06855: Protein of unknown function DUF1250
YP_001033529.1	this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress
YP_001033530.1	IPR008994: Nucleic acid-binding, OB-fold
YP_001033531.1	GNAT family acetyltransferase, PF00583: Acetyltransferase (GNAT) family
YP_001033532.1	Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs
YP_001033533.1	Catalyzes the phosphorylation of UMP to UDP
YP_001033535.1	AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA
YP_001033536.1	PF00871: Acetokinase, TIGR00016: acetate kinase; High confidence in function and specificity
YP_001033537.1	IPR000051: SAM (and some other nucleotide) binding motif
YP_001033538.1	membrane protein
YP_001033539.1	PF00009: Elongation factor Tu GTP binding domain, TIGR01394: GTP-binding protein TypA; Conserved hypothetical protein
YP_001033541.1	membrane protein
YP_001033542.1	secreted protein
YP_001033543.1	PF04397: LytTr DNA-binding region
YP_001033544.1	PF06014: Bacterial protein of unknown function (DUF910)
YP_001033545.1	PF00480: ROK family, TIGR00744: ROK family protein ( glucokinase); High confidence in function and specificity
YP_001033546.1	PF00581: Rhodanese-like domain
YP_001033548.1	PF00210: Ferritin-like domain; High confidence in function and specificity
YP_001033549.1	PF01478: Peptidase A24A, prepilin type IV, PF06750: Bacterial Peptidase A24 N-terminal domain; High confidence in function and specificity
YP_001033550.1	involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function
YP_001033551.1	IPR007214: YbaK/prolyl-tRNA synthetase associated region
YP_001033552.1	PF00324: Amino acid permease-associated region, TIGR00905: arginine/ornithine antiporter; Conserved hypothetical protein
YP_001033553.1	associated with arginine deiminase pathway genes; probably functions in arginine catabolism
YP_001033554.1	catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP
YP_001033555.1	catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP
YP_001033556.1	PF00324:Amino acid permease-associated region, TIGR00905: arginine/ornithine antiporter; High confidence in function and specificity
YP_001033557.1	catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway
YP_001033558.1	catalyzes the degradation of arginine to citruline and ammonia
YP_001033559.1	catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase
YP_001033560.1	PF01316: Arginine repressor, PF02863: Arginine repressor, C-terminal domain, TIGR01529: arginine repressor; High confidence in function and specificity
YP_001033561.1	Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis
YP_001033563.1	PF00176:SNF2 family N-terminal domain; Family membership
YP_001033565.1	PF02776: Thiamine pyrophosphate enzyme, N-terminal TPP binding domain, TIGR00118: acetolactate synthase, large subunit, biosynthetic type; High confidence in function and specificity
YP_001033566.1	PF00144: Beta-lactamase
YP_001033567.1	Conserved hypothetical protein
YP_001033569.1	IPR009002: FMN-binding split barrel
YP_001033570.1	PF02517: CAAX amino terminal protease ,  Abortive infection protein; Conserved hypothetical protein
YP_001033571.1	PF00230: Major intrinsic protein, TIGR00861: MIP family channel proteins; Family membership
YP_001033572.1	catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue
YP_001033573.1	PF07722: Peptidase C26
YP_001033574.1	PF00497: Bacterial extracellular solute-binding protein, family 3; Family membership
YP_001033575.1	PF00070: Pyridine nucleotide-disulphide oxidoreductase, TIGR02053: mercuric reductase; High confidence in function and specificity
YP_001033576.1	Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation
YP_001033577.1	PF00857: Isochorismatase hydrolase, Hypothetical isochorismatase; Family membership
YP_001033578.1	PF00126: Bacterial regulatory helix-turn-helix protein, lysR family; Conserved hypothetical protein; ORF3
YP_001033579.1	PF01569: PAP2 superfamily,  membrane- associated phospholipid phosphatase; Conserved hypothetical protein
YP_001033580.1	PF00583: Acetyltransferase (GNAT) family; Conserved hypothetical protein
YP_001033581.1	PF06304: Protein of unknown function (DUF1048)
YP_001033582.1	PF06304: Protein of unknown function (DUF1048)
YP_001033583.1	PF03551: Transcriptional regulator PadR-like family; Family membership
YP_001033584.1	IPR009002: FMN-binding split barrel
YP_001033586.1	PF06912: Protein of unknown function DUF1275; Conserved hypothetical protein
YP_001033587.1	Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents
YP_001033588.1	PF00535: Glycosyl transferase, family 2; Family membership
YP_001033589.1	TIGR01656 : histidinol-phosphate phosphatase domain, hisB like protein; High confidence in function and specificity
YP_001033590.1	PF01380: Sugar isomerase (SIS domain), TIGR00441: phosphoheptose isomerase; High confidence in function and specificity
YP_001033591.1	PF00288: GHMP kinases  ATP-binding protein; Family membership
YP_001033592.1	Conserved hypothetical protein
YP_001033593.1	PF01531: Glycosyl transferase, family 11; Family membership
YP_001033594.1	PF00535: Glycosyl transferase, family 2; Family membership
YP_001033595.1	PF00535: Glycosyl transferase, family 2; Family membership
YP_001033596.1	PF02388: FemAB family, considered as a factor influencing the level of methicillin resistance in Staphylococcus aureus; Conserved hypothetical protein
YP_001033597.1	is a component of the macrolide binding site in the peptidyl transferase center
YP_001033598.1	catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme
YP_001033599.1	located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3
YP_001033600.1	located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA
YP_001033601.1	smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif
YP_001033602.1	stimulates the activities of the other two initiation factors, IF-2 and IF-3
YP_001033603.1	essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP
YP_001033604.1	forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase
YP_001033605.1	late assembly protein
YP_001033606.1	L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7
YP_001033607.1	located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance
YP_001033608.1	binds 5S rRNA along with protein L5 and L25
YP_001033609.1	ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance
YP_001033610.1	binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
YP_001033613.1	located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif
YP_001033614.1	part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13
YP_001033615.1	assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel
YP_001033616.1	binds to the 23S rRNA between the centers for peptidyl transferase and GTPase
YP_001033617.1	primary binding protein; helps mediate assembly; involved in translation fidelity
YP_001033618.1	one of the stabilizing components for the large ribosomal subunit
YP_001033619.1	located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e
YP_001033620.1	forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation
YP_001033621.1	binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center
YP_001033622.1	protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YP_001033623.1	one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation
YP_001033624.1	binds third domain of 23S rRNA and protein L29; part of exit tunnel
YP_001033625.1	L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA
YP_001033626.1	binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin
YP_001033627.1	NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex
YP_001033628.1	forms homopentamer; channel that opens in response to pressure or hypoosmotic shock
YP_001033629.1	multidrug resistance protein, PF01554: MatE, TIGR00797MATE efflux family protein
YP_001033630.1	catalyzes the formation of L-threonine from O-phospho-L-homoserine
YP_001033631.1	Modulates Rho-dependent transcription termination
YP_001033632.1	forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force
YP_001033633.1	in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif
YP_001033634.1	acyltransferase, PF01757: Acyltransferase; Conserved hypothetical protein
YP_001033635.1	PF00912: Transglycosylase; High confidence in function and specificity
YP_001033636.1	PF04239: Protein of unknown function DUF421
YP_001033638.1	FMN-binding protein, IPR009002: FMN- binding split barrel
YP_001033639.1	PF00849: RNA pseudouridylate synthase , TIGR00005: ribosomal large subunit pseudouridine synthases, RluD subfamily; High confidence in function and specificity
YP_001033640.1	PF00950: ABC-3 transport family; High confidence in function and specificity
YP_001033641.1	PF00005: ABC transporter; High confidence in function and specificity
YP_001033642.1	PF01297.7: Periplasmic solute binding protein family; High confidence in function and specificity
YP_001033643.1	PF01047.9: Bacterial regulatory protein, MarR; High confidence in function and specificity
YP_001033647.1	High confidence in function and specificity
YP_001033648.1	Specificity unclear
YP_001033649.1	PF00482: Bacterial type II secretion system protein F domain,  membrane protein; Conserved hypothetical protein
YP_001033650.1	PF00437: Type II/IV secretion system protein; Conserved hypothetical protein
YP_001033651.1	catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity
YP_001033653.1	catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro)
YP_001033654.1	PF02163: Peptidase M50, TIGR00054: membrane- associated zinc metalloprotease, High confidence in function and specificity
YP_001033655.1	PF01148.9: Phosphatidate cytidylyltransferase, PF01148: Cytidylyltransferase; High confidence in function and specificity
YP_001033656.1	catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate
YP_001033657.1	PF02699: Preprotein translocase subunit, TIGR00739: preprotein translocase, YajC subunit
YP_001033659.1	SPOUT methyltransferase; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA
YP_001033660.1	serine protease, PF00089: Trypsin, TIGR02037: degP_htrA_DO (protease DO); High confidence in function and specificity
YP_001033661.1	PF00534: Glycosyl transferasegroup 1
YP_001033662.1	PF00534: Glycosyl transferases group 1
YP_001033665.1	PF01367: SAM (and some other nucleotide) binding motif
YP_001033666.1	has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair
YP_001033667.1	TIGR00099: Cof-like hydrolase
YP_001033668.1	Sigma factor, regulation of competence
YP_001033669.1	acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation
YP_001033670.1	EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu
YP_001033671.1	one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit
YP_001033673.1	PF00465.7: Iron-containing alcohol dehydrogenase; High confidence in function and specificity
YP_001033676.1	Region start changed from 2386948 to 2386933 (-15 bases)
YP_001033677.1	PF04055: Radical SAM superfamily; Family membership
YP_001033678.1	TIGR01716: Transcriptional activator Rgg/GadR/MutR, C-terminal domain, IPR010057: Transcriptional activator Rgg/GadR/MutR, C-terminal; Conserved hypothetical protein
YP_001033679.1	PF07690: Major facilitator superfamily MFS_1
YP_001033680.1	Coenzyme PQQ synthesis protein E , PF04055: Radical SAM superfamily, IPR006638 Elongator protein 3/MiaB/NifB; High confidence in function and specificity
YP_001033682.1	Conserved hypothetical protein
YP_001033683.1	Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA
YP_001033684.1	PF03602:Conserved hypothetical protein 95, TIGR00095: methyltransferase
YP_001033685.1	PF07690: Major facilitator superfamilyI, TIGR00880: Multidrug resistance protein; Conserved hypothetical protein
YP_001033686.1	PF07690: Major facilitator superfamily I, TIGR00880: Multidrug resistance protein; High confidence in function and specificity
YP_001033688.1	functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family
YP_001033689.1	PF03692.4: Protein of unknown function UPF0153
YP_001033690.1	alcohol dehydrogenase
YP_001033691.1	transcriptional regulator, IPR010982: Lambda repressor-like, DNA-binding
YP_001033693.1	PF01638: Protein of unknown function DUF24, predicted transcriptional regulator; Conserved hypothetical protein
YP_001033695.1	valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain
YP_001033698.1	PF07299: Fibronectin-binding protein (FBP)
YP_001033700.1	PF02575: Protein of unknown function DUF419
YP_001033702.1	PF03483: B3/4 domain
YP_001033703.1	PF01938: TRAM domain, TIGR00479: 23S rRNA (uracil-5- )-methyltransferase RumA; Conserved hypothetical protein
YP_001033704.1	PF06458: MucBP domain
YP_001033705.1	binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities
YP_001033706.1	PF02447: GntP family permease, TIGR00791: gluconate transporter; High confidence in function and specificity
YP_001033707.1	PF00370: FGGY family of carbohydrate kinases, N- terminal domain, TIGR01314: gntK_FGGY: gluconate kinase; High confidence in function and specificity
YP_001033708.1	similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate
YP_001033709.1	PF01418: Helix-turn-helix domain, RpiR family , PF01380: SIS domain sugar isomerase domain; Conserved hypothetical protein
YP_001033711.1	IPR004843: Metallophosphoesterase
YP_001033712.1	binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit
YP_001033713.1	binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA
YP_001033714.1	binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21
YP_001033715.1	BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell
YP_001033716.1	Region start changed from 2433717 to 2433657 (60 bases)
YP_001033717.1	catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA
YP_001033718.1	IPR011009: Protein kinase-like
YP_001033719.1	GAF
YP_001033720.1	PF01817: Chorismate mutase type II, TIGR01805: CM_mono_grmpos: chorismate mutase; Family membership
YP_001033723.1	PF00120: Glutamine synthetase, catalytic domain, TIGR00653: glutamine synthetase, type I; High confidence in function and specificity
YP_001033724.1	GLNR, MerR family transcriptional regulator; High confidence in function and specificity
YP_001033725.1	PF01451: Low molecular weight phosphotyrosine protein phosphatase; High confidence in function and specificity
YP_001033726.1	promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration
YP_001033727.1	plays an essential role in ATP-dependent branch migration of the Holliday junction
YP_001033728.1	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
YP_001033730.1	This protein performs the mismatch recognition step during the DNA repair process
YP_001033732.1	PF00872: Transposase, Mutator family; Conserved hypothetical protein
YP_001033733.1	TIGR01505: 2-hydroxy-3-oxopropionate reductase; Conserved hypothetical protein
YP_001033734.1	Region start changed from 2452228 to 2452270 (42 bases)
YP_001033735.1	PF07843: Protein of unknown function (DUF1634)
YP_001033736.1	PF01925: Protein of unknown function DUF81
YP_001033738.1	catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate
YP_001033739.1	TIGR01668: HAD-superfamily, subfamily IIIA phosphatase
YP_001033740.1	chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion
YP_001033741.1	PF01177: Asp/Glu/Hydantoin racemase; High confidence in function and specificity
YP_001033743.1	Asparagine synthetase (glutamine-hydrolyzing), PF00733: Asparagine synthase; High confidence in function and specificity
YP_001033744.1	PF05257: CHAP domain, IPR011050: Pectin lyase- like; Conserved hypothetical protein
YP_001033745.1	Region start changed from 2464405 to 2464456 (51 bases)
YP_001033746.1	in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall
YP_001033748.1	Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway
YP_001033749.1	IPR000595: cNMP_binding , CRP/FNR family of transcription regulators; Family membership
YP_001033750.1	Region start changed from 2468930 to 2468918 (-12 bases)
YP_001033751.1	PF00582: Universal stress protein family
YP_001033753.1	TIGR00241: CoA-substrate-specific enzyme activase, , PF01869: BadF/BadG/BcrA/BcrD ATPase; Family membership
YP_001033754.1	Region start changed from 2474583 to 2474592 (-9 bases)
YP_001033755.1	Region start changed from 2476018 to 2476276 (258 bases)
YP_001033757.1	in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE
YP_001033759.1	catalyzes branch migration in Holliday junction intermediates
YP_001033760.1	TIGR00686: Alkylphosphonate utilization operon protein PhnA; Conserved hypothetical protein
YP_001033761.1	PF00589: Phage integrase; Conserved hypothetical protein
YP_001033762.1	IPR010982: Lambda repressor-like, DNA-binding
YP_001033764.1	phage associated
YP_001033765.1	IPR009061:  DNA binding, phage associated
YP_001033766.1	Phage associated
YP_001033767.1	CDS
YP_001033770.1	Similar to prophage ps105 in L. lactis IL1403,  DNA primase, PF03288: Poxvirus D5 protein-like
YP_001033771.1	Similar to prophage ps104 in L. lactis IL1403
YP_001033773.1	Similar to prophage ps102, PF05263: Protein of unknown function DUF722
YP_001033774.1	Similar to ps101 in L. lactis IL1403
YP_001033775.1	TIGR01534: Glyceraldehyde-3-phosphate dehydrogenase, type I, PF02800: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; High confidence in function and specificity
YP_001033777.1	Specificity unclear
YP_001033778.1	Region start changed from 2497709 to 2497655 (-54 bases)
YP_001033780.1	membrane protein
YP_001033781.1	forms a direct contact with the tRNA during translation
YP_001033782.1	in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit
YP_001033785.1	An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids
YP_001033786.1	Signal peptidase I (Leader peptidase I)., TIGR02227: Peptidase S26A, signal peptidase I; High confidence in function and specificity
YP_001033787.1	TIGR01743: purR_Bsub, PF00156: Phosphoribosyl transferase domain; High confidence in function and specificity
YP_001033789.1	membrane protein
YP_001033790.1	membrane protein
YP_001033791.1	membrane protein
YP_001033792.1	EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene
YP_001033793.1	binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit
YP_001033794.1	interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance
YP_001033796.1	D-alanyl-D-alanine carboxypeptidase precursor, PF00768: D-alanyl-D-alanine carboxypeptidase; High confidence in function and specificity
YP_001033797.1	Pf06800: Sugartransport protein, TIGR00776 RhaT: RhaT L-rhamnose-proton symporter family protein; Family membership
YP_001033798.1	Pfam:  rRNA methylase; Family membership
YP_001033799.1	PF04055: Radical SAM superfamily, TIGR01212 family: radical SAM protein; Family membership