-- dump date 20140619_125910 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_594379.1 94986446 4060374 358..1794 1 NC_008011.1 DNA replication initiation ATPase 1794 dnaA 4060374 dnaA Lawsonia intracellularis PHE/MN1-00 DNA replication initiation ATPase YP_594379.1 358 D 363253 CDS YP_594380.1 94986447 4060307 complement(1827..2906) 1 NC_008011.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 2906 prfA 4060307 prfA Lawsonia intracellularis PHE/MN1-00 peptide chain release factor 1 YP_594380.1 1827 R 363253 CDS YP_594381.1 94986448 4060308 3122..3436 1 NC_008011.1 hypothetical protein 3436 4060308 LI0003 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594381.1 3122 D 363253 CDS YP_594382.1 94986449 4059687 3454..4209 1 NC_008011.1 hemolysin A 4209 hly 4059687 hly Lawsonia intracellularis PHE/MN1-00 hemolysin A YP_594382.1 3454 D 363253 CDS YP_594383.1 94986450 4059803 complement(4337..4879) 1 NC_008011.1 superoxide dismutase precursor (Cu-Zn) 4879 sodC 4059803 sodC Lawsonia intracellularis PHE/MN1-00 superoxide dismutase precursor (Cu-Zn) YP_594383.1 4337 R 363253 CDS YP_594384.1 94986451 4060309 4945..5214 1 NC_008011.1 hypothetical protein 5214 4060309 LI0006 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594384.1 4945 D 363253 CDS YP_594385.1 94986452 4059826 5549..7147 1 NC_008011.1 nucleotide transport protein 7147 tlc 4059826 tlc Lawsonia intracellularis PHE/MN1-00 nucleotide transport protein YP_594385.1 5549 D 363253 CDS YP_594386.1 94986453 4059474 complement(7665..7904) 1 NC_008011.1 hypothetical protein 7904 4059474 LI0008 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594386.1 7665 R 363253 CDS YP_594387.1 94986454 4059475 complement(8001..8735) 1 NC_008011.1 hypothetical protein 8735 4059475 LI0009 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594387.1 8001 R 363253 CDS YP_594388.1 94986455 4059476 complement(8623..8928) 1 NC_008011.1 hypothetical protein 8928 4059476 LI0010 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594388.1 8623 R 363253 CDS YP_594389.1 94986456 4060002 complement(9617..10576) 1 NC_008011.1 DNA polymerase I 10576 polB 4060002 polB Lawsonia intracellularis PHE/MN1-00 DNA polymerase I YP_594389.1 9617 R 363253 CDS YP_594390.1 94986457 4059477 complement(10536..13571) 1 NC_008011.1 hypothetical protein 13571 4059477 LI0012 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594390.1 10536 R 363253 CDS YP_594391.1 94986458 4059478 complement(14779..15576) 1 NC_008011.1 1-acyl-sn-glycerol-3-phosphate acyltransferase 15576 4059478 LI0013 Lawsonia intracellularis PHE/MN1-00 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_594391.1 14779 R 363253 CDS YP_594392.1 94986459 4059479 complement(15573..16805) 1 NC_008011.1 recombination factor protein RarA 16805 4059479 LI0014 Lawsonia intracellularis PHE/MN1-00 recombination factor protein RarA YP_594392.1 15573 R 363253 CDS YP_594393.1 94986460 4059606 complement(16842..17369) 1 NC_008011.1 pyrimidine operon attenuation protein/uracil phosphoribosyltransferase 17369 upp 4059606 upp Lawsonia intracellularis PHE/MN1-00 pyrimidine operon attenuation protein/uracil phosphoribosyltransferase YP_594393.1 16842 R 363253 CDS YP_594394.1 94986461 4059480 17612..18394 1 NC_008011.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 18394 4059480 LI0016 Lawsonia intracellularis PHE/MN1-00 16S ribosomal RNA methyltransferase RsmE YP_594394.1 17612 D 363253 CDS YP_594395.1 94986462 4059510 complement(18406..19131) 1 NC_008011.1 ubiquinone/menaquinone biosynthesis methylase 19131 ubiE 4059510 ubiE Lawsonia intracellularis PHE/MN1-00 ubiquinone/menaquinone biosynthesis methylase YP_594395.1 18406 R 363253 CDS YP_594396.1 94986463 4060223 complement(19389..20660) 1 NC_008011.1 proton/sodium-glutamate symport protein 20660 gltP 4060223 gltP Lawsonia intracellularis PHE/MN1-00 proton/sodium-glutamate symport protein YP_594396.1 19389 R 363253 CDS YP_594397.1 94986464 4059809 complement(20974..21483) 1 NC_008011.1 glycerol-3-phosphate cytidyltransferase 21483 tagD 4059809 tagD Lawsonia intracellularis PHE/MN1-00 glycerol-3-phosphate cytidyltransferase YP_594397.1 20974 R 363253 CDS YP_594398.1 94986465 4059499 complement(21519..22526) 1 NC_008011.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 22526 trpS 4059499 trpS Lawsonia intracellularis PHE/MN1-00 tryptophanyl-tRNA synthetase YP_594398.1 21519 R 363253 CDS YP_594399.1 94986466 4059481 complement(22529..23203) 1 NC_008011.1 Zn-dependent proteases 23203 4059481 LI0021 Lawsonia intracellularis PHE/MN1-00 Zn-dependent proteases YP_594399.1 22529 R 363253 CDS YP_594400.1 94986467 4059509 complement(23206..24402) 1 NC_008011.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 24402 tyrS 4059509 tyrS Lawsonia intracellularis PHE/MN1-00 tyrosyl-tRNA synthetase YP_594400.1 23206 R 363253 CDS YP_594401.1 94986468 4060071 complement(24563..25084) 1 NC_008011.1 O-6-alkylguanine-DNA/cysteine-protein methyltransferase 25084 ogt 4060071 ogt Lawsonia intracellularis PHE/MN1-00 O-6-alkylguanine-DNA/cysteine-protein methyltransferase YP_594401.1 24563 R 363253 CDS YP_594402.1 94986469 4060321 complement(25145..26224) 1 NC_008011.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 26224 ispG 4060321 ispG Lawsonia intracellularis PHE/MN1-00 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_594402.1 25145 R 363253 CDS YP_594403.1 94986470 4059975 complement(26307..29891) 1 NC_008011.1 phosphoenolpyruvate synthase/pyruvate phosphate dikinase 29891 ppsA 4059975 ppsA Lawsonia intracellularis PHE/MN1-00 phosphoenolpyruvate synthase/pyruvate phosphate dikinase YP_594403.1 26307 R 363253 CDS YP_594404.1 94986471 4060401 complement(30148..31131) 1 NC_008011.1 biotin-(acetyl-CoA carboxylase) ligase 31131 birA 4060401 birA Lawsonia intracellularis PHE/MN1-00 biotin-(acetyl-CoA carboxylase) ligase YP_594404.1 30148 R 363253 CDS YP_594405.1 94986472 4059743 complement(31207..32184) 1 NC_008011.1 flagellar motor switch protein 32184 fliM 4059743 fliM Lawsonia intracellularis PHE/MN1-00 flagellar motor switch protein YP_594405.1 31207 R 363253 CDS YP_594406.1 94986473 4059482 32258..32746 1 NC_008011.1 hypothetical protein 32746 4059482 LI0028 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594406.1 32258 D 363253 CDS YP_594407.1 94986474 4059483 complement(32974..34476) 1 NC_008011.1 hypothetical protein 34476 4059483 LI0029 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594407.1 32974 R 363253 CDS YP_594408.1 94986475 4059484 complement(34646..35818) 1 NC_008011.1 hypothetical protein 35818 4059484 LI0030 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594408.1 34646 R 363253 CDS YP_594409.1 94986476 4059485 complement(35907..36365) 1 NC_008011.1 hypothetical protein 36365 4059485 LI0031 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594409.1 35907 R 363253 CDS YP_594410.1 94986477 4059486 complement(36644..37960) 1 NC_008011.1 hypothetical protein 37960 4059486 LI0032 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594410.1 36644 R 363253 CDS YP_594411.1 94986478 4060018 complement(38434..40854) 1 NC_008011.1 organic solvent tolerance protein OstA 40854 ostA 4060018 ostA Lawsonia intracellularis PHE/MN1-00 organic solvent tolerance protein OstA YP_594411.1 38434 R 363253 CDS YP_594412.1 94986479 4060345 40989..42131 1 NC_008011.1 alanine racemase 42131 alr 4060345 alr Lawsonia intracellularis PHE/MN1-00 alanine racemase YP_594412.1 40989 D 363253 CDS YP_594413.1 94986480 4060312 complement(42140..42592) 1 NC_008011.1 Fe2+/Zn2+ uptake regulation proteins 42592 fur 4060312 fur Lawsonia intracellularis PHE/MN1-00 Fe2+/Zn2+ uptake regulation proteins YP_594413.1 42140 R 363253 CDS YP_594414.1 94986481 4059947 complement(42906..43955) 1 NC_008011.1 ADP-heptose:LPS heptosyltransferase II 43955 rfaF 4059947 rfaF Lawsonia intracellularis PHE/MN1-00 ADP-heptose:LPS heptosyltransferase II YP_594414.1 42906 R 363253 CDS YP_594415.1 94986482 4059487 complement(44293..44535) 1 NC_008011.1 transcriptional regulator 44535 4059487 LI0037 Lawsonia intracellularis PHE/MN1-00 transcriptional regulator YP_594415.1 44293 R 363253 CDS YP_594416.1 94986483 4059488 44534..45043 1 NC_008011.1 exported nuclease 45043 4059488 LI0038 Lawsonia intracellularis PHE/MN1-00 exported nuclease YP_594416.1 44534 D 363253 CDS YP_594417.1 94986484 4059489 45343..45816 1 NC_008011.1 hypothetical protein 45816 4059489 LI0039 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594417.1 45343 D 363253 CDS YP_594418.1 94986485 4059490 <45849..47372 1 NC_008011.1 hypothetical protein 47372 4059490 LI0040 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594418.1 <45849 D 363253 CDS YP_594419.1 94986486 4059491 47683..49611 1 NC_008011.1 hypothetical protein 49611 4059491 LI0041 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594419.1 47683 D 363253 CDS YP_594420.1 94986487 4059492 49861..50334 1 NC_008011.1 hypothetical protein 50334 4059492 LI0042 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594420.1 49861 D 363253 CDS YP_594421.1 94986488 4060033 50406..53108 1 NC_008011.1 hypothetical protein 53108 4060033 LI0043 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594421.1 50406 D 363253 CDS YP_594422.1 94986489 4060147 complement(53869..55779) 1 NC_008011.1 hypothetical protein 55779 mdoB 4060147 mdoB Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594422.1 53869 R 363253 CDS YP_594423.1 94986490 4060034 56748..59387 1 NC_008011.1 hypothetical protein 59387 4060034 LI0045 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594423.1 56748 D 363253 CDS YP_594424.1 94986491 4060035 60142..60534 1 NC_008011.1 hypothetical protein 60534 4060035 LI0046 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594424.1 60142 D 363253 CDS YP_594425.1 94986492 4059637 complement(61583..62695) 1 NC_008011.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 62695 secF 4059637 secF Lawsonia intracellularis PHE/MN1-00 preprotein translocase subunit SecF YP_594425.1 61583 R 363253 CDS YP_594426.1 94986493 4059636 complement(62698..64281) 1 NC_008011.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 64281 secD 4059636 secD Lawsonia intracellularis PHE/MN1-00 preprotein translocase subunit SecD YP_594426.1 62698 R 363253 CDS YP_594427.1 94986494 4059617 complement(64432..64770) 1 NC_008011.1 preprotein translocase subunit YajC 64770 yajC 4059617 yajC Lawsonia intracellularis PHE/MN1-00 preprotein translocase subunit YajC YP_594427.1 64432 R 363253 CDS YP_594428.1 94986495 4060036 complement(65816..69043) 1 NC_008011.1 uncharacterized protein involved in outer membrane biogenesis 69043 4060036 LI0050 Lawsonia intracellularis PHE/MN1-00 uncharacterized protein involved in outer membrane biogenesis YP_594428.1 65816 R 363253 CDS YP_594429.1 94986496 4059609 complement(69095..72304) 1 NC_008011.1 ATP-dependent exoDNAse beta subunit 72304 uvrD 4059609 uvrD Lawsonia intracellularis PHE/MN1-00 ATP-dependent exoDNAse beta subunit YP_594429.1 69095 R 363253 CDS YP_594430.1 94986497 4060031 complement(72270..73637) 1 NC_008011.1 catalyzes the formation of fructose 1,6-bisphosphate from fructose 6-phosphate and diphosphate; diphosphate--fructose-6-phosphate 1-phosphotransferase 73637 pfp 4060031 pfp Lawsonia intracellularis PHE/MN1-00 diphosphate--fructose-6-phosphate 1-phosphotransferase YP_594430.1 72270 R 363253 CDS YP_594431.1 94986498 4060037 74229..74561 1 NC_008011.1 hypothetical protein 74561 4060037 LI0053 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594431.1 74229 D 363253 CDS YP_594432.1 94986499 4060038 complement(74909..75781) 1 NC_008011.1 rRNA methylases 75781 4060038 LI0054 Lawsonia intracellularis PHE/MN1-00 rRNA methylases YP_594432.1 74909 R 363253 CDS YP_594433.1 94986500 4060122 75939..77606 1 NC_008011.1 membrane-bound lytic murein transglycosylase D (MltD) 77606 mltD 4060122 mltD Lawsonia intracellularis PHE/MN1-00 membrane-bound lytic murein transglycosylase D (MltD) YP_594433.1 75939 D 363253 CDS YP_594434.1 94986501 4060039 complement(77677..78435) 1 NC_008011.1 nitrate ABC transporter, permease (nrtB-1) 78435 4060039 LI0056 Lawsonia intracellularis PHE/MN1-00 nitrate ABC transporter, permease (nrtB-1) YP_594434.1 77677 R 363253 CDS YP_594435.1 94986502 4060040 complement(78432..79178) 1 NC_008011.1 nitrate ABC transporter, ATP-binding protein (nrtC-1) 79178 4060040 LI0057 Lawsonia intracellularis PHE/MN1-00 nitrate ABC transporter, ATP-binding protein (nrtC-1) YP_594435.1 78432 R 363253 CDS YP_594436.1 94986503 4060041 complement(79175..80086) 1 NC_008011.1 thiamine biosynthesis protein 80086 4060041 LI0058 Lawsonia intracellularis PHE/MN1-00 thiamine biosynthesis protein YP_594436.1 79175 R 363253 CDS YP_594437.1 94986504 4060042 80428..80937 1 NC_008011.1 hypothetical protein 80937 4060042 LI0059 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594437.1 80428 D 363253 CDS YP_594438.1 94986505 4060220 81700..82470 1 NC_008011.1 transcriptional regulators of sugar metabolism 82470 glpR 4060220 glpR Lawsonia intracellularis PHE/MN1-00 transcriptional regulators of sugar metabolism YP_594438.1 81700 D 363253 CDS YP_594439.1 94986506 4060043 complement(82557..82877) 1 NC_008011.1 hypothetical protein 82877 4060043 LI0061 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594439.1 82557 R 363253 CDS YP_594440.1 94986507 4059618 complement(83393..84085) 1 NC_008011.1 nicotinic acid mononucleotide adenylyltransferase 84085 ybeN 4059618 ybeN Lawsonia intracellularis PHE/MN1-00 nicotinic acid mononucleotide adenylyltransferase YP_594440.1 83393 R 363253 CDS YP_594441.1 94986508 4060044 84629..85216 1 NC_008011.1 hypothetical protein 85216 4060044 LI0063 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594441.1 84629 D 363253 CDS YP_594442.1 94986509 4060045 85844..86242 1 NC_008011.1 transcriptional regulator 86242 4060045 LI0064 Lawsonia intracellularis PHE/MN1-00 transcriptional regulator YP_594442.1 85844 D 363253 CDS YP_594443.1 94986510 4060046 complement(86420..87169) 1 NC_008011.1 Outer membrane lipoprotein-sorting protein 87169 4060046 LI0065 Lawsonia intracellularis PHE/MN1-00 Outer membrane lipoprotein-sorting protein YP_594443.1 86420 R 363253 CDS YP_594444.1 94986511 4059757 complement(87173..89860) 1 NC_008011.1 DNA segregation ATPase FtsK/SpoIIIE and related proteins 89860 ftsK 4059757 ftsK Lawsonia intracellularis PHE/MN1-00 DNA segregation ATPase FtsK/SpoIIIE and related proteins YP_594444.1 87173 R 363253 CDS YP_594445.1 94986512 4060047 complement(89937..90494) 1 NC_008011.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 90494 4060047 LI0067 Lawsonia intracellularis PHE/MN1-00 elongation factor P YP_594445.1 89937 R 363253 CDS YP_594446.1 94986513 4060048 90801..91409 1 NC_008011.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 91409 engB 4060048 engB Lawsonia intracellularis PHE/MN1-00 ribosome biogenesis GTP-binding protein YsxC YP_594446.1 90801 D 363253 CDS YP_594447.1 94986514 4060049 92957..93616 1 NC_008011.1 hypothetical protein 93616 4060049 LI0069 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594447.1 92957 D 363253 CDS YP_594448.1 94986515 4060050 93731..94156 1 NC_008011.1 hypothetical protein 94156 4060050 LI0070 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594448.1 93731 D 363253 CDS YP_594449.1 94986516 4060051 94285..94833 1 NC_008011.1 hypothetical protein 94833 4060051 LI0071 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594449.1 94285 D 363253 CDS YP_594450.1 94986517 4060052 94921..95379 1 NC_008011.1 hypothetical protein 95379 4060052 LI0072 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594450.1 94921 D 363253 CDS YP_594451.1 94986518 4060269 95597..96073 1 NC_008011.1 hypothetical protein 96073 4060269 LI0073 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594451.1 95597 D 363253 CDS YP_594452.1 94986519 4060270 complement(97539..97961) 1 NC_008011.1 rhodanese-related sulfurtransferase 97961 4060270 LI0074 Lawsonia intracellularis PHE/MN1-00 rhodanese-related sulfurtransferase YP_594452.1 97539 R 363253 CDS YP_594453.1 94986520 4059666 98193..98996 1 NC_008011.1 phosphodiesterase 98996 icc 4059666 icc Lawsonia intracellularis PHE/MN1-00 phosphodiesterase YP_594453.1 98193 D 363253 CDS YP_594454.1 94986521 4060271 99014..100063 1 NC_008011.1 sugar ABC transporter, ATP-binding protein 100063 4060271 LI0076 Lawsonia intracellularis PHE/MN1-00 sugar ABC transporter, ATP-binding protein YP_594454.1 99014 D 363253 CDS YP_594455.1 94986522 4059605 100196..101491 1 NC_008011.1 extracellular solute-binding protein 101491 ugpB 4059605 ugpB Lawsonia intracellularis PHE/MN1-00 extracellular solute-binding protein YP_594455.1 100196 D 363253 CDS YP_594456.1 94986523 4059604 101554..102441 1 NC_008011.1 inner membrane component of binding-protein-dependent transport system 102441 ugpA 4059604 ugpA Lawsonia intracellularis PHE/MN1-00 inner membrane component of binding-protein-dependent transport system YP_594456.1 101554 D 363253 CDS YP_594457.1 94986524 4060272 102438..103274 1 NC_008011.1 inner membrane component of binding-protein-dependent transport system 103274 4060272 LI0079 Lawsonia intracellularis PHE/MN1-00 inner membrane component of binding-protein-dependent transport system YP_594457.1 102438 D 363253 CDS YP_594458.1 94986525 4060273 complement(103384..104913) 1 NC_008011.1 hypothetical protein 104913 4060273 LI0080 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594458.1 103384 R 363253 CDS YP_594459.1 94986526 4060274 105205..106146 1 NC_008011.1 nucleoside-diphosphate sugar epimerase 106146 4060274 LI0081 Lawsonia intracellularis PHE/MN1-00 nucleoside-diphosphate sugar epimerase YP_594459.1 105205 D 363253 CDS YP_594460.1 94986527 4060275 complement(106189..107283) 1 NC_008011.1 hypothetical protein 107283 4060275 LI0082 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594460.1 106189 R 363253 CDS YP_594461.1 94986528 4059678 complement(107298..108380) 1 NC_008011.1 CBS domain-containing protein 108380 kpsF 4059678 kpsF Lawsonia intracellularis PHE/MN1-00 CBS domain-containing protein YP_594461.1 107298 R 363253 CDS YP_594462.1 94986529 4060276 complement(110475..111206) 1 NC_008011.1 hypothetical protein 111206 4060276 LI0084 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594462.1 110475 R 363253 CDS YP_594463.1 94986530 4060379 complement(111603..112004) 1 NC_008011.1 molecular chaperone DnaK 112004 dnaK 4060379 dnaK Lawsonia intracellularis PHE/MN1-00 molecular chaperone DnaK YP_594463.1 111603 R 363253 CDS YP_594464.1 94986531 4060277 complement(112674..113177) 1 NC_008011.1 beta-D-galactosidase 113177 4060277 LI0086 Lawsonia intracellularis PHE/MN1-00 beta-D-galactosidase YP_594464.1 112674 R 363253 CDS YP_594465.1 94986532 4059378 complement(113180..114442) 1 NC_008011.1 catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; acetylornithine aminotransferase 114442 argD 4059378 argD Lawsonia intracellularis PHE/MN1-00 acetylornithine aminotransferase YP_594465.1 113180 R 363253 CDS YP_594466.1 94986533 4059298 complement(114414..114896) 1 NC_008011.1 dUTPase 114896 dut 4059298 dut Lawsonia intracellularis PHE/MN1-00 dUTPase YP_594466.1 114414 R 363253 CDS YP_594467.1 94986534 4059750 115144..115653 1 NC_008011.1 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 115653 folE 4059750 folE Lawsonia intracellularis PHE/MN1-00 7-cyano-7-deazaguanine reductase YP_594467.1 115144 D 363253 CDS YP_594468.1 94986535 4060278 115673..116482 1 NC_008011.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase 116482 4060278 LI0090 Lawsonia intracellularis PHE/MN1-00 pantothenate kinase YP_594468.1 115673 D 363253 CDS YP_594469.1 94986536 4059300 116596..117897 1 NC_008011.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 117897 eno 4059300 eno Lawsonia intracellularis PHE/MN1-00 phosphopyruvate hydratase YP_594469.1 116596 D 363253 CDS YP_594470.1 94986537 4059949 complement(117911..118954) 1 NC_008011.1 ADP-heptose:LPS heptosyltransferase 118954 rfaF/rfaQ 4059949 rfaF/rfaQ Lawsonia intracellularis PHE/MN1-00 ADP-heptose:LPS heptosyltransferase YP_594470.1 117911 R 363253 CDS YP_594471.1 94986538 4060279 119487..120482 1 NC_008011.1 hypothetical protein 120482 4060279 LI0093 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594471.1 119487 D 363253 CDS YP_594472.1 94986539 4060030 120488..121714 1 NC_008011.1 fructose-2,6-bisphosphatase 121714 pfk 4060030 pfk Lawsonia intracellularis PHE/MN1-00 fructose-2,6-bisphosphatase YP_594472.1 120488 D 363253 CDS YP_594473.1 94986540 4060280 complement(121739..123019) 1 NC_008011.1 CheY-like receiver 123019 4060280 LI0095 Lawsonia intracellularis PHE/MN1-00 CheY-like receiver YP_594473.1 121739 R 363253 CDS YP_594474.1 94986541 4060281 complement(123089..123490) 1 NC_008011.1 hypothetical protein 123490 4060281 LI0096 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594474.1 123089 R 363253 CDS YP_594475.1 94986542 4060435 complement(124343..125278) 1 NC_008011.1 CorA, CorA-like Mg2+ transporter protein 125278 corA 4060435 corA Lawsonia intracellularis PHE/MN1-00 CorA, CorA-like Mg2+ transporter protein YP_594475.1 124343 R 363253 CDS YP_594476.1 94986543 4060282 125579..126076 1 NC_008011.1 hypothetical protein 126076 4060282 LI0098 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594476.1 125579 D 363253 CDS YP_594477.1 94986544 4059377 complement(126080..127141) 1 NC_008011.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 127141 argC 4059377 argC Lawsonia intracellularis PHE/MN1-00 N-acetyl-gamma-glutamyl-phosphate reductase YP_594477.1 126080 R 363253 CDS YP_594478.1 94986545 4060283 complement(127145..127495) 1 NC_008011.1 hypothetical protein 127495 4060283 LI0100 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594478.1 127145 R 363253 CDS YP_594479.1 94986546 4060373 complement(127796..128161) 1 NC_008011.1 diacylglycerol kinase 128161 dgkA 4060373 dgkA Lawsonia intracellularis PHE/MN1-00 diacylglycerol kinase YP_594479.1 127796 R 363253 CDS YP_594480.1 94986547 4060003 complement(128189..130795) 1 NC_008011.1 DNA polymerase I 130795 polB 4060003 polB Lawsonia intracellularis PHE/MN1-00 DNA polymerase I YP_594480.1 128189 R 363253 CDS YP_594481.1 94986548 4060284 131168..132442 1 NC_008011.1 hypothetical protein 132442 4060284 LI0103 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594481.1 131168 D 363253 CDS YP_594482.1 94986549 4060285 132452..133093 1 NC_008011.1 hypothetical protein 133093 4060285 LI0104 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594482.1 132452 D 363253 CDS YP_594483.1 94986550 4060286 133237..134181 1 NC_008011.1 hypothetical protein 134181 4060286 LI0105 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594483.1 133237 D 363253 CDS YP_594484.1 94986551 4059668 complement(134353..136017) 1 NC_008011.1 catalyzes the condensation of two pyruvates to form acetolactate, implicated in pH homeostasis via the acetoin-2,3-butanediol pathway or in valine biosynthesis; acetolactate synthase 136017 ilv 4059668 ilv Lawsonia intracellularis PHE/MN1-00 acetolactate synthase YP_594484.1 134353 R 363253 CDS YP_594485.1 94986552 4060287 complement(136036..136965) 1 NC_008011.1 permease 136965 4060287 LI0107 Lawsonia intracellularis PHE/MN1-00 permease YP_594485.1 136036 R 363253 CDS YP_594486.1 94986553 4060445 complement(137267..138253) 1 NC_008011.1 dihydrodipicolinate synthase/N-acetylneuraminate lyase 138253 dapA 4060445 dapA Lawsonia intracellularis PHE/MN1-00 dihydrodipicolinate synthase/N-acetylneuraminate lyase YP_594486.1 137267 R 363253 CDS YP_594487.1 94986554 4060229 138738..139481 1 NC_008011.1 hypothetical protein 139481 4060229 LI0109 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594487.1 138738 D 363253 CDS YP_594488.1 94986555 4059801 139486..140751 1 NC_008011.1 DNA uptake Rossmann fold nucleotide-binding protein 140751 smf 4059801 smf Lawsonia intracellularis PHE/MN1-00 DNA uptake Rossmann fold nucleotide-binding protein YP_594488.1 139486 D 363253 CDS YP_594489.1 94986556 4060230 140818..141759 1 NC_008011.1 site-specific recombinase XerC 141759 4060230 LI0111 Lawsonia intracellularis PHE/MN1-00 site-specific recombinase XerC YP_594489.1 140818 D 363253 CDS YP_594490.1 94986557 4060231 complement(141824..142765) 1 NC_008011.1 hypothetical protein 142765 4060231 LI0112 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594490.1 141824 R 363253 CDS YP_594491.1 94986558 4060232 complement(142958..144319) 1 NC_008011.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 144319 engA 4060232 engA Lawsonia intracellularis PHE/MN1-00 GTP-binding protein EngA YP_594491.1 142958 R 363253 CDS YP_594492.1 94986559 4059643 complement(144414..145688) 1 NC_008011.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 145688 serS 4059643 serS Lawsonia intracellularis PHE/MN1-00 seryl-tRNA synthetase YP_594492.1 144414 R 363253 CDS YP_594493.1 94986560 4060233 145952..146530 1 NC_008011.1 hypothetical protein 146530 4060233 LI0115 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594493.1 145952 D 363253 CDS YP_594494.1 94986561 4060234 146548..147627 1 NC_008011.1 TPR repeat-containing protein 147627 4060234 LI0116 Lawsonia intracellularis PHE/MN1-00 TPR repeat-containing protein YP_594494.1 146548 D 363253 CDS YP_594495.1 94986562 4060441 147699..149210 1 NC_008011.1 siroheme synthase 149210 cysG 4060441 cysG Lawsonia intracellularis PHE/MN1-00 siroheme synthase YP_594495.1 147699 D 363253 CDS YP_594496.1 94986563 4059961 149239..149922 1 NC_008011.1 phosphoribosylglycinamide formyltransferase 149922 purN 4059961 purN Lawsonia intracellularis PHE/MN1-00 phosphoribosylglycinamide formyltransferase YP_594496.1 149239 D 363253 CDS YP_594497.1 94986564 4060073 complement(149998..150498) 1 NC_008011.1 peptide methionine sulfoxide reductase 150498 msrA 4060073 msrA Lawsonia intracellularis PHE/MN1-00 peptide methionine sulfoxide reductase YP_594497.1 149998 R 363253 CDS YP_594498.1 94986565 4060235 complement(150473..150880) 1 NC_008011.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; a fusion protein of this enzyme with MsrA and thioredoxin provides protection against oxidative stress in Neisseria gonorrhoeae; methionine sulfoxide reductase B 150880 4060235 LI0120 Lawsonia intracellularis PHE/MN1-00 methionine sulfoxide reductase B YP_594498.1 150473 R 363253 CDS YP_594499.1 94986566 4060028 complement(150925..151581) 1 NC_008011.1 Xaa-Pro aminopeptidase 151581 pepQ 4060028 pepQ Lawsonia intracellularis PHE/MN1-00 Xaa-Pro aminopeptidase YP_594499.1 150925 R 363253 CDS YP_594500.1 94986567 4060236 152230..152988 1 NC_008011.1 cytochrome c biogenesis protein 152988 4060236 LI0122 Lawsonia intracellularis PHE/MN1-00 cytochrome c biogenesis protein YP_594500.1 152230 D 363253 CDS YP_594501.1 94986568 4059680 complement(153127..153696) 1 NC_008011.1 maltose O-acetyltransferase 153696 lacA 4059680 lacA Lawsonia intracellularis PHE/MN1-00 maltose O-acetyltransferase YP_594501.1 153127 R 363253 CDS YP_594502.1 94986569 4060408 154211..155119 1 NC_008011.1 DnaJ-class molecular chaperone 155119 cbpA 4060408 cbpA Lawsonia intracellularis PHE/MN1-00 DnaJ-class molecular chaperone YP_594502.1 154211 D 363253 CDS YP_594503.1 94986570 4060237 155138..155449 1 NC_008011.1 hypothetical protein 155449 4060237 LI0125 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594503.1 155138 D 363253 CDS YP_594504.1 94986571 4060425 155540..158173 1 NC_008011.1 ATPases with chaperone activity, ATP-binding subunit 158173 clpB 4060425 clpB Lawsonia intracellularis PHE/MN1-00 ATPases with chaperone activity, ATP-binding subunit YP_594504.1 155540 D 363253 CDS YP_594505.1 94986572 4060214 complement(158235..158993) 1 NC_008011.1 ABC-type polar amino acid transport system, ATPase component 158993 glnQ 4060214 glnQ Lawsonia intracellularis PHE/MN1-00 ABC-type polar amino acid transport system, ATPase component YP_594505.1 158235 R 363253 CDS YP_594506.1 94986573 4060211 complement(158962..159747) 1 NC_008011.1 ABC-type amino acid transport system, permease component 159747 glnP 4060211 glnP Lawsonia intracellularis PHE/MN1-00 ABC-type amino acid transport system, permease component YP_594506.1 158962 R 363253 CDS YP_594507.1 94986574 4060238 complement(159798..160547) 1 NC_008011.1 amino acid ABC transporter substrate-binding protein 160547 4060238 LI0129 Lawsonia intracellularis PHE/MN1-00 amino acid ABC transporter substrate-binding protein YP_594507.1 159798 R 363253 CDS YP_594508.1 94986575 4059685 160881..161474 1 NC_008011.1 histidinol phosphatase and related phosphatases 161474 hisJ 4059685 hisJ Lawsonia intracellularis PHE/MN1-00 histidinol phosphatase and related phosphatases YP_594508.1 160881 D 363253 CDS YP_594509.1 94986576 4059749 161575..162882 1 NC_008011.1 folylpolyglutamate synthase 162882 folC 4059749 folC Lawsonia intracellularis PHE/MN1-00 folylpolyglutamate synthase YP_594509.1 161575 D 363253 CDS YP_594510.1 94986577 4059640 162904..164340 1 NC_008011.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase 164340 selA 4059640 selA Lawsonia intracellularis PHE/MN1-00 selenocysteine synthase YP_594510.1 162904 D 363253 CDS YP_594511.1 94986578 4060239 164510..164863 1 NC_008011.1 hypothetical protein 164863 4060239 LI0133 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594511.1 164510 D 363253 CDS YP_594512.1 94986579 4060240 164954..166084 1 NC_008011.1 polymerase 166084 4060240 LI0134 Lawsonia intracellularis PHE/MN1-00 polymerase YP_594512.1 164954 D 363253 CDS YP_594513.1 94986580 4060241 166090..167793 1 NC_008011.1 hypothetical protein 167793 4060241 LI0135 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594513.1 166090 D 363253 CDS YP_594514.1 94986581 4060242 169098..169745 1 NC_008011.1 hypothetical protein 169745 4060242 LI0136 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594514.1 169098 D 363253 CDS YP_594515.1 94986582 4060243 complement(170015..170803) 1 NC_008011.1 integral membrane protein 170803 4060243 LI0137 Lawsonia intracellularis PHE/MN1-00 integral membrane protein YP_594515.1 170015 R 363253 CDS YP_594516.1 94986583 4060244 complement(171157..171543) 1 NC_008011.1 hypothetical protein 171543 4060244 LI0138 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594516.1 171157 R 363253 CDS YP_594517.1 94986584 4060245 complement(171577..172059) 1 NC_008011.1 hypothetical protein 172059 4060245 LI0139 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594517.1 171577 R 363253 CDS YP_594518.1 94986585 4060246 complement(172266..173522) 1 NC_008011.1 glycosyltransferase 173522 4060246 LI0140 Lawsonia intracellularis PHE/MN1-00 glycosyltransferase YP_594518.1 172266 R 363253 CDS YP_594519.1 94986586 4060060 173721..174680 1 NC_008011.1 xylanase/chitin deacetylase 174680 nodB 4060060 nodB Lawsonia intracellularis PHE/MN1-00 xylanase/chitin deacetylase YP_594519.1 173721 D 363253 CDS YP_594520.1 94986587 4060247 178242..179129 1 NC_008011.1 hypothetical protein 179129 4060247 LI0142 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594520.1 178242 D 363253 CDS YP_594521.1 94986588 4060248 complement(180054..180455) 1 NC_008011.1 hypothetical protein 180455 4060248 LI0143 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594521.1 180054 R 363253 CDS YP_594522.1 94986589 4059857 complement(180718..181446) 1 NC_008011.1 SAM-dependent methyltransferases 181446 4059857 LI0144 Lawsonia intracellularis PHE/MN1-00 SAM-dependent methyltransferases YP_594522.1 180718 R 363253 CDS YP_594523.1 94986590 4059508 182088..183926 1 NC_008011.1 GTP-binding protein LepA 183926 typA/bipA 4059508 typA/bipA Lawsonia intracellularis PHE/MN1-00 GTP-binding protein LepA YP_594523.1 182088 D 363253 CDS YP_594524.1 94986591 4059858 complement(183980..185080) 1 NC_008011.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 185080 4059858 LI0146 Lawsonia intracellularis PHE/MN1-00 GTP-dependent nucleic acid-binding protein EngD YP_594524.1 183980 R 363253 CDS YP_594525.1 94986592 4059859 185352..185810 1 NC_008011.1 Outer membrane lipoprotein 185810 4059859 LI0147 Lawsonia intracellularis PHE/MN1-00 Outer membrane lipoprotein YP_594525.1 185352 D 363253 CDS YP_594526.1 94986593 4059661 complement(185906..188398) 1 NC_008011.1 ATP-dependent protease 188398 lon 4059661 lon Lawsonia intracellularis PHE/MN1-00 ATP-dependent protease YP_594526.1 185906 R 363253 CDS YP_594527.1 94986594 4059937 complement(188436..189116) 1 NC_008011.1 DNA repair proteins 189116 radC 4059937 radC Lawsonia intracellularis PHE/MN1-00 DNA repair proteins YP_594527.1 188436 R 363253 CDS YP_594528.1 94986595 4059860 complement(189211..190188) 1 NC_008011.1 hypothetical protein 190188 4059860 LI0150 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594528.1 189211 R 363253 CDS YP_594529.1 94986596 4059861 complement(190209..190736) 1 NC_008011.1 hypothetical protein 190736 4059861 LI0151 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594529.1 190209 R 363253 CDS YP_594530.1 94986597 4059645 complement(190747..193254) 1 NC_008011.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 193254 leuS 4059645 leuS Lawsonia intracellularis PHE/MN1-00 leucyl-tRNA synthetase YP_594530.1 190747 R 363253 CDS YP_594531.1 94986598 4060069 complement(193265..193750) 1 NC_008011.1 transcription termination factor 193750 nusB 4060069 nusB Lawsonia intracellularis PHE/MN1-00 transcription termination factor YP_594531.1 193265 R 363253 CDS YP_594532.1 94986599 4059900 complement(193760..194233) 1 NC_008011.1 riboflavin synthase beta-chain 194233 ribH 4059900 ribH Lawsonia intracellularis PHE/MN1-00 riboflavin synthase beta-chain YP_594532.1 193760 R 363253 CDS YP_594533.1 94986600 4059896 complement(194320..>195588) 1 NC_008011.1 GTP cyclohydrolase II >195588 ribA 4059896 ribA Lawsonia intracellularis PHE/MN1-00 GTP cyclohydrolase II YP_594533.1 194320 R 363253 CDS YP_594534.1 94986601 4059898 complement(195573..196238) 1 NC_008011.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 196238 ribE 4059898 ribE Lawsonia intracellularis PHE/MN1-00 riboflavin synthase subunit alpha YP_594534.1 195573 R 363253 CDS YP_594535.1 94986602 4059897 complement(196242..197390) 1 NC_008011.1 pyrimidine reductase, riboflavin biosynthesis 197390 ribD 4059897 ribD Lawsonia intracellularis PHE/MN1-00 pyrimidine reductase, riboflavin biosynthesis YP_594535.1 196242 R 363253 CDS YP_594536.1 94986603 4060225 complement(197926..199164) 1 NC_008011.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 199164 glyA 4060225 glyA Lawsonia intracellularis PHE/MN1-00 serine hydroxymethyltransferase YP_594536.1 197926 R 363253 CDS YP_594537.1 94986604 4059303 complement(199233..200483) 1 NC_008011.1 3-oxoacyl-ACP synthase 200483 fabF/fabB 4059303 fabF/fabB Lawsonia intracellularis PHE/MN1-00 3-oxoacyl-ACP synthase YP_594537.1 199233 R 363253 CDS YP_594538.1 94986605 4059304 complement(200903..201646) 1 NC_008011.1 3-oxoacyl-ACP reductase 201646 fabG 4059304 fabG Lawsonia intracellularis PHE/MN1-00 3-oxoacyl-ACP reductase YP_594538.1 200903 R 363253 CDS YP_594539.1 94986606 4059305 complement(201755..202759) 1 NC_008011.1 3-oxoacyl-ACP synthase 202759 fabH 4059305 fabH Lawsonia intracellularis PHE/MN1-00 3-oxoacyl-ACP synthase YP_594539.1 201755 R 363253 CDS YP_594540.1 94986607 4060000 complement(202841..203884) 1 NC_008011.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 203884 plsX 4060000 plsX Lawsonia intracellularis PHE/MN1-00 glycerol-3-phosphate acyltransferase PlsX YP_594540.1 202841 R 363253 CDS YP_594541.1 94986608 4059862 complement(204107..204643) 1 NC_008011.1 metal-binding protein 204643 4059862 LI0164 Lawsonia intracellularis PHE/MN1-00 metal-binding protein YP_594541.1 204107 R 363253 CDS YP_594542.1 94986609 4060085 complement(204755..205846) 1 NC_008011.1 A/G-specific adenine glycosylase 205846 mutY 4060085 mutY Lawsonia intracellularis PHE/MN1-00 A/G-specific adenine glycosylase YP_594542.1 204755 R 363253 CDS YP_594543.1 94986610 4059974 205977..206483 1 NC_008011.1 peptidyl-prolyl cis-trans isomerase 206483 ppiB 4059974 ppiB Lawsonia intracellularis PHE/MN1-00 peptidyl-prolyl cis-trans isomerase YP_594543.1 205977 D 363253 CDS YP_594544.1 94986611 4059863 complement(206826..207434) 1 NC_008011.1 peptidyl-prolyl cis-trans isomerase 207434 4059863 LI0167 Lawsonia intracellularis PHE/MN1-00 peptidyl-prolyl cis-trans isomerase YP_594544.1 206826 R 363253 CDS YP_594545.1 94986612 4059864 complement(207522..210743) 1 NC_008011.1 SNF2 family DNA/RNA helicase 210743 4059864 LI0168 Lawsonia intracellularis PHE/MN1-00 SNF2 family DNA/RNA helicase YP_594545.1 207522 R 363253 CDS YP_594546.1 94986613 4060013 <211599..>213256 1 NC_008011.1 ABC-type dipeptide transport system, periplasmic component >213256 oppA 4060013 oppA Lawsonia intracellularis PHE/MN1-00 ABC-type dipeptide transport system, periplasmic component YP_594546.1 <211599 D 363253 CDS YP_594547.1 94986614 4059945 213386..215581 1 NC_008011.1 guanosine polyphosphate pyrophosphohydrolases/synthetases 215581 relA 4059945 relA Lawsonia intracellularis PHE/MN1-00 guanosine polyphosphate pyrophosphohydrolases/synthetases YP_594547.1 213386 D 363253 CDS YP_594548.1 94986615 4059865 complement(215599..216006) 1 NC_008011.1 hypothetical protein 216006 4059865 LI0171 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594548.1 215599 R 363253 CDS YP_594549.1 94986616 4059866 complement(216601..217899) 1 NC_008011.1 hypothetical protein 217899 4059866 LI0172 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594549.1 216601 R 363253 CDS YP_594550.1 94986617 4059867 <218703..219869 1 NC_008011.1 prophage DLP12 integrase 219869 4059867 LI0173 Lawsonia intracellularis PHE/MN1-00 prophage DLP12 integrase YP_594550.1 <218703 D 363253 CDS YP_594551.1 94986618 4059868 219859..220869 1 NC_008011.1 hypothetical protein 220869 4059868 LI0174 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594551.1 219859 D 363253 CDS YP_594552.1 94986619 4059869 221210..222874 1 NC_008011.1 hypothetical protein 222874 4059869 LI0175 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594552.1 221210 D 363253 CDS YP_594553.1 94986620 4059870 222965..223357 1 NC_008011.1 hypothetical protein 223357 4059870 LI0176 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594553.1 222965 D 363253 CDS YP_594554.1 94986621 4059871 223987..224532 1 NC_008011.1 hypothetical protein 224532 4059871 LI0177 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594554.1 223987 D 363253 CDS YP_594555.1 94986622 4059872 224690..225184 1 NC_008011.1 hypothetical protein 225184 4059872 LI0178 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594555.1 224690 D 363253 CDS YP_594556.1 94986623 4059813 complement(225939..227858) 1 NC_008011.1 ribosomal protection tetracycline resistance protein 227858 tetW 4059813 tetW Lawsonia intracellularis PHE/MN1-00 ribosomal protection tetracycline resistance protein YP_594556.1 225939 R 363253 CDS YP_594557.1 94986624 4059873 228343..229257 1 NC_008011.1 hypothetical protein 229257 4059873 LI0180 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594557.1 228343 D 363253 CDS YP_594558.1 94986625 4059874 229471..230256 1 NC_008011.1 endonuclease I 230256 4059874 LI0181 Lawsonia intracellularis PHE/MN1-00 endonuclease I YP_594558.1 229471 D 363253 CDS YP_594559.1 94986626 4059875 230232..231092 1 NC_008011.1 recombination protein-phage associated 231092 4059875 LI0182 Lawsonia intracellularis PHE/MN1-00 recombination protein-phage associated YP_594559.1 230232 D 363253 CDS YP_594560.1 94986627 4060170 231161..232363 1 NC_008011.1 hypothetical protein 232363 4060170 LI0183 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594560.1 231161 D 363253 CDS YP_594561.1 94986628 4060171 232347..232721 1 NC_008011.1 hypothetical protein 232721 4060171 LI0184 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594561.1 232347 D 363253 CDS YP_594562.1 94986629 4060172 232791..233741 1 NC_008011.1 MoxR-like ATPases 233741 4060172 LI0185 Lawsonia intracellularis PHE/MN1-00 MoxR-like ATPases YP_594562.1 232791 D 363253 CDS YP_594563.1 94986630 4060173 233745..234740 1 NC_008011.1 hypothetical protein 234740 4060173 LI0186 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594563.1 233745 D 363253 CDS YP_594564.1 94986631 4060174 234755..236347 1 NC_008011.1 hypothetical protein 236347 4060174 LI0187 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594564.1 234755 D 363253 CDS YP_594565.1 94986632 4059755 236969..238876 1 NC_008011.1 ATP-dependent Zn proteases 238876 ftsH 4059755 ftsH Lawsonia intracellularis PHE/MN1-00 ATP-dependent Zn proteases YP_594565.1 236969 D 363253 CDS YP_594566.1 94986633 4059752 238888..239775 1 NC_008011.1 dihydropteroate synthase 239775 folP 4059752 folP Lawsonia intracellularis PHE/MN1-00 dihydropteroate synthase YP_594566.1 238888 D 363253 CDS YP_594567.1 94986634 4060175 239839..240579 1 NC_008011.1 hypothetical protein 240579 4060175 LI0190 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594567.1 239839 D 363253 CDS YP_594568.1 94986635 4060176 240772..241494 1 NC_008011.1 hypothetical protein 241494 4060176 LI0191 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594568.1 240772 D 363253 CDS YP_594569.1 94986636 4060177 241522..242877 1 NC_008011.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 242877 glmM 4060177 glmM Lawsonia intracellularis PHE/MN1-00 phosphoglucosamine mutase YP_594569.1 241522 D 363253 CDS YP_594570.1 94986637 4060317 242878..243798 1 NC_008011.1 UDP-glucose pyrophosphorylase 243798 galU 4060317 galU Lawsonia intracellularis PHE/MN1-00 UDP-glucose pyrophosphorylase YP_594570.1 242878 D 363253 CDS YP_594571.1 94986638 4059979 243833..246211 1 NC_008011.1 primosomal protein N' 246211 priA 4059979 priA Lawsonia intracellularis PHE/MN1-00 primosomal protein N' YP_594571.1 243833 D 363253 CDS YP_594572.1 94986639 4060178 247238..247885 1 NC_008011.1 SAM-dependent methyltransferases 247885 4060178 LI0195 Lawsonia intracellularis PHE/MN1-00 SAM-dependent methyltransferases YP_594572.1 247238 D 363253 CDS YP_594573.1 94986640 4060179 247882..249495 1 NC_008011.1 transport protein 249495 4060179 LI0196 Lawsonia intracellularis PHE/MN1-00 transport protein YP_594573.1 247882 D 363253 CDS YP_594574.1 94986641 4060180 complement(249535..250242) 1 NC_008011.1 endo-1,4-beta-xylanase 250242 4060180 LI0197 Lawsonia intracellularis PHE/MN1-00 endo-1,4-beta-xylanase YP_594574.1 249535 R 363253 CDS YP_594575.1 94986642 4060181 complement(250367..250963) 1 NC_008011.1 membrane protein 250963 4060181 LI0198 Lawsonia intracellularis PHE/MN1-00 membrane protein YP_594575.1 250367 R 363253 CDS YP_594576.1 94986643 4060182 complement(250984..253005) 1 NC_008011.1 exoribonuclease R 253005 4060182 LI0199 Lawsonia intracellularis PHE/MN1-00 exoribonuclease R YP_594576.1 250984 R 363253 CDS YP_594577.1 94986644 4059955 complement(253065..254339) 1 NC_008011.1 AICAR transformylase/IMP cyclohydrolase PurH 254339 purH 4059955 purH Lawsonia intracellularis PHE/MN1-00 AICAR transformylase/IMP cyclohydrolase PurH YP_594577.1 253065 R 363253 CDS YP_594578.1 94986645 4060183 254566..254889 1 NC_008011.1 hypothetical protein 254889 4060183 LI0201 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594578.1 254566 D 363253 CDS YP_594579.1 94986646 4059989 255142..256428 1 NC_008011.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 256428 purA 4059989 purA Lawsonia intracellularis PHE/MN1-00 adenylosuccinate synthetase YP_594579.1 255142 D 363253 CDS YP_594580.1 94986647 4059837 256593..257651 1 NC_008011.1 tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase 257651 trmU 4059837 trmU Lawsonia intracellularis PHE/MN1-00 tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase YP_594580.1 256593 D 363253 CDS YP_594581.1 94986648 4060184 257733..258917 1 NC_008011.1 Fe-S oxidoreductases 258917 4060184 LI0204 Lawsonia intracellularis PHE/MN1-00 Fe-S oxidoreductases YP_594581.1 257733 D 363253 CDS YP_594582.1 94986649 4060261 259031..260029 1 NC_008011.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 260029 hemB 4060261 hemB Lawsonia intracellularis PHE/MN1-00 delta-aminolevulinic acid dehydratase YP_594582.1 259031 D 363253 CDS YP_594583.1 94986650 4060185 260014..261327 1 NC_008011.1 Fe-S oxidoreductases 261327 4060185 LI0206 Lawsonia intracellularis PHE/MN1-00 Fe-S oxidoreductases YP_594583.1 260014 D 363253 CDS YP_594584.1 94986651 4060058 261332..261784 1 NC_008011.1 transcriptional regulators 261784 nirD 4060058 nirD Lawsonia intracellularis PHE/MN1-00 transcriptional regulators YP_594584.1 261332 D 363253 CDS YP_594585.1 94986652 4060186 261947..262936 1 NC_008011.1 hypothetical protein 262936 4060186 LI0208 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594585.1 261947 D 363253 CDS YP_594586.1 94986653 4060187 263206..263820 1 NC_008011.1 hypothetical protein 263820 4060187 LI0209 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594586.1 263206 D 363253 CDS YP_594587.1 94986654 4059747 complement(264303..264875) 1 NC_008011.1 flagellin-specific chaperone FliS 264875 fliS 4059747 fliS Lawsonia intracellularis PHE/MN1-00 flagellin-specific chaperone FliS YP_594587.1 264303 R 363253 CDS YP_594588.1 94986655 4059737 complement(264907..266991) 1 NC_008011.1 flagellar capping protein 266991 fliD 4059737 fliD Lawsonia intracellularis PHE/MN1-00 flagellar capping protein YP_594588.1 264907 R 363253 CDS YP_594589.1 94986656 4059823 267658..269586 1 NC_008011.1 threonyl-tRNA synthetase 269586 thrS 4059823 thrS Lawsonia intracellularis PHE/MN1-00 threonyl-tRNA synthetase YP_594589.1 267658 D 363253 CDS YP_594590.1 94986657 4060188 269654..270130 1 NC_008011.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 270130 infC 4060188 infC Lawsonia intracellularis PHE/MN1-00 translation initiation factor IF-3 YP_594590.1 269654 D 363253 CDS YP_594591.1 94986658 4059893 270500..270853 1 NC_008011.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 270853 rplT 4059893 rplT Lawsonia intracellularis PHE/MN1-00 50S ribosomal protein L20 YP_594591.1 270500 D 363253 CDS YP_594592.1 94986659 4059997 270937..271974 1 NC_008011.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 271974 pheS 4059997 pheS Lawsonia intracellularis PHE/MN1-00 phenylalanyl-tRNA synthetase subunit alpha YP_594592.1 270937 D 363253 CDS YP_594593.1 94986660 4059998 272014..274425 1 NC_008011.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 274425 pheT 4059998 pheT Lawsonia intracellularis PHE/MN1-00 phenylalanyl-tRNA synthetase subunit beta YP_594593.1 272014 D 363253 CDS YP_594594.1 94986661 4060189 274466..274882 1 NC_008011.1 transcriptional regulator 274882 4060189 LI0217 Lawsonia intracellularis PHE/MN1-00 transcriptional regulator YP_594594.1 274466 D 363253 CDS YP_594595.1 94986662 4059912 275097..275564 1 NC_008011.1 Pentose-5-phosphate-3-epimerase 275564 rpe 4059912 rpe Lawsonia intracellularis PHE/MN1-00 Pentose-5-phosphate-3-epimerase YP_594595.1 275097 D 363253 CDS YP_594596.1 94986663 4059825 275627..277594 1 NC_008011.1 transketolase 277594 tkt 4059825 tkt Lawsonia intracellularis PHE/MN1-00 transketolase YP_594596.1 275627 D 363253 CDS YP_594597.1 94986664 4059836 277821..278945 1 NC_008011.1 tRNA-(guanine-N1)-methyltransferase 278945 trmD 4059836 trmD Lawsonia intracellularis PHE/MN1-00 tRNA-(guanine-N1)-methyltransferase YP_594597.1 277821 D 363253 CDS YP_594598.1 94986665 4059891 278981..279328 1 NC_008011.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 279328 rplS 4059891 rplS Lawsonia intracellularis PHE/MN1-00 50S ribosomal protein L19 YP_594598.1 278981 D 363253 CDS YP_594599.1 94986666 4059892 279395..280069 1 NC_008011.1 ribonuclease HII 280069 rplS 4059892 rplS Lawsonia intracellularis PHE/MN1-00 ribonuclease HII YP_594599.1 279395 D 363253 CDS YP_594600.1 94986667 4059760 280089..280487 1 NC_008011.1 hypothetical protein 280487 4059760 LI0223 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594600.1 280089 D 363253 CDS YP_594601.1 94986668 4059761 280429..281259 1 NC_008011.1 methyltransferases 281259 4059761 LI0224 Lawsonia intracellularis PHE/MN1-00 methyltransferases YP_594601.1 280429 D 363253 CDS YP_594602.1 94986669 4059802 281262..281729 1 NC_008011.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 281729 smpB 4059802 smpB Lawsonia intracellularis PHE/MN1-00 SsrA-binding protein YP_594602.1 281262 D 363253 CDS YP_594603.1 94986670 4059534 281750..283432 1 NC_008011.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein 283432 yjjK 4059534 yjjK Lawsonia intracellularis PHE/MN1-00 ABC transporter ATP-binding protein YP_594603.1 281750 D 363253 CDS YP_594604.1 94986671 4059302 complement(283562..284482) 1 NC_008011.1 ACP S-malonyltransferase 284482 fabD 4059302 fabD Lawsonia intracellularis PHE/MN1-00 ACP S-malonyltransferase YP_594604.1 283562 R 363253 CDS YP_594605.1 94986672 4060221 complement(284607..285644) 1 NC_008011.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 285644 glpX 4060221 glpX Lawsonia intracellularis PHE/MN1-00 fructose 1,6-bisphosphatase II YP_594605.1 284607 R 363253 CDS YP_594606.1 94986673 4059383 285821..287473 1 NC_008011.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 287473 argS 4059383 argS Lawsonia intracellularis PHE/MN1-00 arginyl-tRNA synthetase YP_594606.1 285821 D 363253 CDS YP_594607.1 94986674 4059762 287480..288256 1 NC_008011.1 hypothetical protein 288256 4059762 LI0230 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594607.1 287480 D 363253 CDS YP_594608.1 94986675 4059763 288273..289073 1 NC_008011.1 ABC-type transport system involved in resistance to organic solvents, permease component 289073 4059763 LI0231 Lawsonia intracellularis PHE/MN1-00 ABC-type transport system involved in resistance to organic solvents, permease component YP_594608.1 288273 D 363253 CDS YP_594609.1 94986676 4059764 289086..289916 1 NC_008011.1 ABC-type transport system involved in resistance to organic solvents, ATPase component 289916 4059764 LI0232 Lawsonia intracellularis PHE/MN1-00 ABC-type transport system involved in resistance to organic solvents, ATPase component YP_594609.1 289086 D 363253 CDS YP_594610.1 94986677 4059765 289932..290375 1 NC_008011.1 ABC-type transport system involved in resistance to organic solvents, periplasmic component 290375 4059765 LI0233 Lawsonia intracellularis PHE/MN1-00 ABC-type transport system involved in resistance to organic solvents, periplasmic component YP_594610.1 289932 D 363253 CDS YP_594611.1 94986678 4059766 290380..291030 1 NC_008011.1 ABC-type transport system involved in resistance to organic solvents, auxiliary component 291030 4059766 LI0234 Lawsonia intracellularis PHE/MN1-00 ABC-type transport system involved in resistance to organic solvents, auxiliary component YP_594611.1 290380 D 363253 CDS YP_594612.1 94986679 4059767 291031..291927 1 NC_008011.1 surface lipoprotein 291927 4059767 LI0235 Lawsonia intracellularis PHE/MN1-00 surface lipoprotein YP_594612.1 291031 D 363253 CDS YP_594613.1 94986680 4060083 complement(292398..295079) 1 NC_008011.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 295079 mutS 4060083 mutS Lawsonia intracellularis PHE/MN1-00 DNA mismatch repair protein MutS YP_594613.1 292398 R 363253 CDS YP_594614.1 94986681 4059768 complement(295534..296034) 1 NC_008011.1 diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases 296034 4059768 LI0237 Lawsonia intracellularis PHE/MN1-00 diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases YP_594614.1 295534 R 363253 CDS YP_594615.1 94986682 4060409 complement(296154..297827) 1 NC_008011.1 poly(A) polymerase 297827 cca 4060409 cca Lawsonia intracellularis PHE/MN1-00 poly(A) polymerase YP_594615.1 296154 R 363253 CDS YP_594616.1 94986683 4059769 complement(297994..298914) 1 NC_008011.1 site-specific recombinase 298914 4059769 LI0239 Lawsonia intracellularis PHE/MN1-00 site-specific recombinase YP_594616.1 297994 R 363253 CDS YP_594617.1 94986684 4059751 299096..299647 1 NC_008011.1 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase 299647 folk 4059751 folk Lawsonia intracellularis PHE/MN1-00 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase YP_594617.1 299096 D 363253 CDS YP_594618.1 94986685 4059607 300171..302201 1 NC_008011.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 302201 uvrB 4059607 uvrB Lawsonia intracellularis PHE/MN1-00 excinuclease ABC subunit B YP_594618.1 300171 D 363253 CDS YP_594619.1 94986686 4059648 302221..304269 1 NC_008011.1 NAD-dependent DNA ligase 304269 lig 4059648 lig Lawsonia intracellularis PHE/MN1-00 NAD-dependent DNA ligase YP_594619.1 302221 D 363253 CDS YP_594620.1 94986687 4060369 304286..305062 1 NC_008011.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 305062 dapB 4060369 dapB Lawsonia intracellularis PHE/MN1-00 dihydrodipicolinate reductase YP_594620.1 304286 D 363253 CDS YP_594621.1 94986688 4060090 305063..306640 1 NC_008011.1 NH(3)-dependent NAD(+) synthetase 306640 nadE 4060090 nadE Lawsonia intracellularis PHE/MN1-00 NH(3)-dependent NAD(+) synthetase YP_594621.1 305063 D 363253 CDS YP_594622.1 94986689 4059701 complement(306735..307415) 1 NC_008011.1 hydrogenase accessory protein HypB 307415 hypB 4059701 hypB Lawsonia intracellularis PHE/MN1-00 hydrogenase accessory protein HypB YP_594622.1 306735 R 363253 CDS YP_594623.1 94986690 4059700 complement(307426..307782) 1 NC_008011.1 zinc finger protein 307782 hypA 4059700 hypA Lawsonia intracellularis PHE/MN1-00 zinc finger protein YP_594623.1 307426 R 363253 CDS YP_594624.1 94986691 4059770 308027..308794 1 NC_008011.1 hypothetical protein 308794 4059770 LI0247 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594624.1 308027 D 363253 CDS YP_594625.1 94986692 4059771 308869..309519 1 NC_008011.1 hypothetical protein 309519 4059771 LI0248 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594625.1 308869 D 363253 CDS YP_594626.1 94986693 4059941 complement(309567..311150) 1 NC_008011.1 DNA repair ATPase 311150 recN 4059941 recN Lawsonia intracellularis PHE/MN1-00 DNA repair ATPase YP_594626.1 309567 R 363253 CDS YP_594627.1 94986694 4060015 complement(311205..312023) 1 NC_008011.1 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components 312023 oppC 4060015 oppC Lawsonia intracellularis PHE/MN1-00 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_594627.1 311205 R 363253 CDS YP_594628.1 94986695 4060014 complement(312032..313036) 1 NC_008011.1 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components 313036 oppB 4060014 oppB Lawsonia intracellularis PHE/MN1-00 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_594628.1 312032 R 363253 CDS YP_594629.1 94986696 4059772 complement(313191..313712) 1 NC_008011.1 hypothetical protein 313712 4059772 LI0252 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594629.1 313191 R 363253 CDS YP_594630.1 94986697 4059773 complement(313725..314339) 1 NC_008011.1 hypothetical protein 314339 4059773 LI0253 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594630.1 313725 R 363253 CDS YP_594631.1 94986698 4059774 314561..315688 1 NC_008011.1 hypothetical protein 315688 4059774 LI0254 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594631.1 314561 D 363253 CDS YP_594632.1 94986699 4059775 complement(315691..316236) 1 NC_008011.1 hypothetical protein 316236 4059775 LI0255 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594632.1 315691 R 363253 CDS YP_594633.1 94986700 4059776 complement(316238..317029) 1 NC_008011.1 hypothetical protein 317029 4059776 LI0256 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594633.1 316238 R 363253 CDS YP_594634.1 94986701 4060376 317243..320752 1 NC_008011.1 DNA polymerase III, alpha subunit 320752 dnaE 4060376 dnaE Lawsonia intracellularis PHE/MN1-00 DNA polymerase III, alpha subunit YP_594634.1 317243 D 363253 CDS YP_594635.1 94986702 4059777 320772..321152 1 NC_008011.1 F0F1-type ATP synthase, subunit c 321152 4059777 LI0258 Lawsonia intracellularis PHE/MN1-00 F0F1-type ATP synthase, subunit c YP_594635.1 320772 D 363253 CDS YP_594636.1 94986703 4059778 complement(321305..321553) 1 NC_008011.1 hypothetical protein 321553 4059778 LI0259 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594636.1 321305 R 363253 CDS YP_594637.1 94986704 4060067 321744..323993 1 NC_008011.1 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation 323993 ntrY 4060067 ntrY Lawsonia intracellularis PHE/MN1-00 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation YP_594637.1 321744 D 363253 CDS YP_594638.1 94986705 4060314 complement(324064..325572) 1 NC_008011.1 glutamate decarboxylase isozyme 325572 gad 4060314 gad Lawsonia intracellularis PHE/MN1-00 glutamate decarboxylase isozyme YP_594638.1 324064 R 363253 CDS YP_594639.1 94986706 4059779 complement(325627..327084) 1 NC_008011.1 amino acid transporters 327084 4059779 LI0262 Lawsonia intracellularis PHE/MN1-00 amino acid transporters YP_594639.1 325627 R 363253 CDS YP_594640.1 94986707 4059780 327353..328624 1 NC_008011.1 amino acid-amine transport protein 328624 4059780 LI0263 Lawsonia intracellularis PHE/MN1-00 amino acid-amine transport protein YP_594640.1 327353 D 363253 CDS YP_594641.1 94986708 4059954 328991..330241 1 NC_008011.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 330241 rho 4059954 rho Lawsonia intracellularis PHE/MN1-00 transcription termination factor Rho YP_594641.1 328991 D 363253 CDS YP_594642.1 94986709 4059781 complement(330371..331534) 1 NC_008011.1 cysteine sulfinate desulfinase/cysteine desulfurase 331534 4059781 LI0265 Lawsonia intracellularis PHE/MN1-00 cysteine sulfinate desulfinase/cysteine desulfurase YP_594642.1 330371 R 363253 CDS YP_594643.1 94986710 4059670 complement(331531..>332373) 1 NC_008011.1 NifU homolog involved in Fe-S cluster formation >332373 iscU 4059670 iscU Lawsonia intracellularis PHE/MN1-00 NifU homolog involved in Fe-S cluster formation YP_594643.1 331531 R 363253 CDS YP_594644.1 94986711 4059782 complement(333321..333689) 1 NC_008011.1 hypothetical protein 333689 4059782 LI0267 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594644.1 333321 R 363253 CDS YP_594645.1 94986712 4059631 complement(333806..334312) 1 NC_008011.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 334312 ruvC 4059631 ruvC Lawsonia intracellularis PHE/MN1-00 Holliday junction resolvase YP_594645.1 333806 R 363253 CDS YP_594646.1 94986713 4059620 complement(334384..335124) 1 NC_008011.1 hypothetical protein 335124 yebC 4059620 yebC Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594646.1 334384 R 363253 CDS YP_594647.1 94986714 4059622 complement(335173..335775) 1 NC_008011.1 23S rRNA methylase 335775 ygcA 4059622 ygcA Lawsonia intracellularis PHE/MN1-00 23S rRNA methylase YP_594647.1 335173 R 363253 CDS YP_594648.1 94986715 4059783 335866..337446 1 NC_008011.1 hypothetical protein 337446 4059783 LI0271 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594648.1 335866 D 363253 CDS YP_594649.1 94986716 4059784 337458..338414 1 NC_008011.1 hypothetical protein 338414 4059784 LI0272 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594649.1 337458 D 363253 CDS YP_594650.1 94986717 4059785 338687..339097 1 NC_008011.1 desulfoferrodoxin 339097 4059785 LI0273 Lawsonia intracellularis PHE/MN1-00 desulfoferrodoxin YP_594650.1 338687 D 363253 CDS YP_594651.1 94986718 4059786 339468..340676 1 NC_008011.1 uncharacterized flavoproteins 340676 4059786 LI0274 Lawsonia intracellularis PHE/MN1-00 uncharacterized flavoproteins YP_594651.1 339468 D 363253 CDS YP_594652.1 94986719 4060440 340816..342117 1 NC_008011.1 cytochrome bd-type quinol oxidase, subunit 1 342117 cyoB 4060440 cyoB Lawsonia intracellularis PHE/MN1-00 cytochrome bd-type quinol oxidase, subunit 1 YP_594652.1 340816 D 363253 CDS YP_594653.1 94986720 4060439 342150..343178 1 NC_008011.1 cytochrome bd-type quinol oxidase, subunit 2 343178 cyoA 4060439 cyoA Lawsonia intracellularis PHE/MN1-00 cytochrome bd-type quinol oxidase, subunit 2 YP_594653.1 342150 D 363253 CDS YP_594654.1 94986721 4059787 complement(343350..343829) 1 NC_008011.1 hypothetical protein 343829 4059787 LI0277 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594654.1 343350 R 363253 CDS YP_594655.1 94986722 4060004 344241..347804 1 NC_008011.1 pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit 347804 porA 4060004 porA Lawsonia intracellularis PHE/MN1-00 pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit YP_594655.1 344241 D 363253 CDS YP_594656.1 94986723 4059988 347892..350012 1 NC_008011.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 350012 pta 4059988 pta Lawsonia intracellularis PHE/MN1-00 phosphate acetyltransferase YP_594656.1 347892 D 363253 CDS YP_594657.1 94986724 4060339 350112..351326 1 NC_008011.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 351326 ackA 4060339 ackA Lawsonia intracellularis PHE/MN1-00 acetate kinase YP_594657.1 350112 D 363253 CDS YP_594658.1 94986725 4060118 complement(351351..352262) 1 NC_008011.1 tRNA delta(2)-isopentenylpyrophosphate transferase 352262 miaA 4060118 miaA Lawsonia intracellularis PHE/MN1-00 tRNA delta(2)-isopentenylpyrophosphate transferase YP_594658.1 351351 R 363253 CDS YP_594659.1 94986726 4059676 complement(352309..352827) 1 NC_008011.1 phosphopantetheine adenylyltransferase 352827 kdtB 4059676 kdtB Lawsonia intracellularis PHE/MN1-00 phosphopantetheine adenylyltransferase YP_594659.1 352309 R 363253 CDS YP_594660.1 94986727 4059788 complement(352803..353375) 1 NC_008011.1 N6-adenine-specific methylase 353375 4059788 LI0283 Lawsonia intracellularis PHE/MN1-00 N6-adenine-specific methylase YP_594660.1 352803 R 363253 CDS YP_594661.1 94986728 4059789 complement(353516..355117) 1 NC_008011.1 RNA processing exonuclease 355117 4059789 LI0284 Lawsonia intracellularis PHE/MN1-00 RNA processing exonuclease YP_594661.1 353516 R 363253 CDS YP_594662.1 94986729 4059790 complement(355243..356610) 1 NC_008011.1 cell wall-associated hydrolases (invasion-associated proteins) 356610 4059790 LI0285 Lawsonia intracellularis PHE/MN1-00 cell wall-associated hydrolases (invasion-associated proteins) YP_594662.1 355243 R 363253 CDS YP_594663.1 94986730 4059791 complement(356715..358055) 1 NC_008011.1 cell wall-associated hydrolases (invasion-associated proteins) 358055 4059791 LI0286 Lawsonia intracellularis PHE/MN1-00 cell wall-associated hydrolases (invasion-associated proteins) YP_594663.1 356715 R 363253 CDS YP_594664.1 94986731 4059939 complement(358069..360267) 1 NC_008011.1 exonuclease V subunit alpha 360267 recD 4059939 recD Lawsonia intracellularis PHE/MN1-00 exonuclease V subunit alpha YP_594664.1 358069 R 363253 CDS YP_594665.1 94986732 4059792 361133..362386 1 NC_008011.1 PAP2 superfamily protein 362386 4059792 LI0288 Lawsonia intracellularis PHE/MN1-00 PAP2 superfamily protein YP_594665.1 361133 D 363253 CDS YP_594666.1 94986733 4059793 complement(362504..363340) 1 NC_008011.1 pirin 363340 4059793 LI0289 Lawsonia intracellularis PHE/MN1-00 pirin YP_594666.1 362504 R 363253 CDS YP_594667.1 94986734 4059794 complement(363544..364893) 1 NC_008011.1 hypothetical protein 364893 4059794 LI0290 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594667.1 363544 R 363253 CDS YP_594668.1 94986735 4059795 complement(365970..367550) 1 NC_008011.1 hypothetical protein 367550 4059795 LI0291 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594668.1 365970 R 363253 CDS YP_594669.1 94986736 4059796 367971..368636 1 NC_008011.1 Svh 368636 4059796 LI0292 Lawsonia intracellularis PHE/MN1-00 Svh YP_594669.1 367971 D 363253 CDS YP_594670.1 94986737 4060311 complement(369577..370143) 1 NC_008011.1 fumarate hydratase 370143 fumB 4060311 fumB Lawsonia intracellularis PHE/MN1-00 fumarate hydratase YP_594670.1 369577 R 363253 CDS YP_594671.1 94986738 4060310 complement(370169..371014) 1 NC_008011.1 Catalyzes the reversible hydration of fumaric acid to yield I-malic acid; fumarate hydratase 371014 fumA 4060310 fumA Lawsonia intracellularis PHE/MN1-00 fumarate hydratase YP_594671.1 370169 R 363253 CDS YP_594672.1 94986739 4059797 complement(371279..371884) 1 NC_008011.1 hypothetical protein 371884 4059797 LI0295 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594672.1 371279 R 363253 CDS YP_594673.1 94986740 4059960 complement(372325..373374) 1 NC_008011.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 373374 purM 4059960 purM Lawsonia intracellularis PHE/MN1-00 phosphoribosylaminoimidazole synthetase YP_594673.1 372325 R 363253 CDS YP_594674.1 94986741 4059798 373444..373821 1 NC_008011.1 hypothetical protein 373821 4059798 LI0297 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594674.1 373444 D 363253 CDS YP_594675.1 94986742 4060288 373843..374799 1 NC_008011.1 hypothetical protein 374799 4060288 LI0298 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594675.1 373843 D 363253 CDS YP_594676.1 94986743 4060227 complement(375220..377307) 1 NC_008011.1 glycyl-tRNA synthetase, beta subunit 377307 glyS 4060227 glyS Lawsonia intracellularis PHE/MN1-00 glycyl-tRNA synthetase, beta subunit YP_594676.1 375220 R 363253 CDS YP_594677.1 94986744 4060226 complement(377313..378197) 1 NC_008011.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 378197 glyQ 4060226 glyQ Lawsonia intracellularis PHE/MN1-00 glycyl-tRNA synthetase subunit alpha YP_594677.1 377313 R 363253 CDS YP_594678.1 94986745 4059942 complement(378253..379002) 1 NC_008011.1 hypothetical protein 379002 recO 4059942 recO Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594678.1 378253 R 363253 CDS YP_594679.1 94986746 4060289 complement(379007..380026) 1 NC_008011.1 hypothetical protein 380026 4060289 LI0302 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594679.1 379007 R 363253 CDS YP_594680.1 94986747 4060012 complement(380045..380971) 1 NC_008011.1 parvulin-like peptidyl-prolyl isomerase 380971 ppi 4060012 ppi Lawsonia intracellularis PHE/MN1-00 parvulin-like peptidyl-prolyl isomerase YP_594680.1 380045 R 363253 CDS YP_594681.1 94986748 4060290 complement(381141..382058) 1 NC_008011.1 parvulin-like peptidyl-prolyl isomerase 382058 4060290 LI0304 Lawsonia intracellularis PHE/MN1-00 parvulin-like peptidyl-prolyl isomerase YP_594681.1 381141 R 363253 CDS YP_594682.1 94986749 4060291 complement(382096..385563) 1 NC_008011.1 transcription-repair coupling factor 385563 4060291 LI0305 Lawsonia intracellularis PHE/MN1-00 transcription-repair coupling factor YP_594682.1 382096 R 363253 CDS YP_594683.1 94986750 4060292 complement(385645..387228) 1 NC_008011.1 integral membrane protein 387228 4060292 LI0306 Lawsonia intracellularis PHE/MN1-00 integral membrane protein YP_594683.1 385645 R 363253 CDS YP_594684.1 94986751 4060253 387513..387986 1 NC_008011.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 387986 greA 4060253 greA Lawsonia intracellularis PHE/MN1-00 transcription elongation factor GreA YP_594684.1 387513 D 363253 CDS YP_594685.1 94986752 4060293 388048..389358 1 NC_008011.1 2-methylthioadenine synthetase 389358 4060293 LI0308 Lawsonia intracellularis PHE/MN1-00 2-methylthioadenine synthetase YP_594685.1 388048 D 363253 CDS YP_594686.1 94986753 4059532 389463..390344 1 NC_008011.1 hypothetical protein 390344 yicC 4059532 yicC Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594686.1 389463 D 363253 CDS YP_594687.1 94986754 4060249 390597..391235 1 NC_008011.1 guanylate kinase 391235 gmk 4060249 gmk Lawsonia intracellularis PHE/MN1-00 guanylate kinase YP_594687.1 390597 D 363253 CDS YP_594688.1 94986755 4059969 391242..391931 1 NC_008011.1 orotidine-5'-phosphate decarboxylase 391931 pyrF 4059969 pyrF Lawsonia intracellularis PHE/MN1-00 orotidine-5'-phosphate decarboxylase YP_594688.1 391242 D 363253 CDS YP_594689.1 94986756 4060294 392001..392819 1 NC_008011.1 TPR repeat-containing protein 392819 4060294 LI0312 Lawsonia intracellularis PHE/MN1-00 TPR repeat-containing protein YP_594689.1 392001 D 363253 CDS YP_594690.1 94986757 4059940 392879..394585 1 NC_008011.1 single-stranded DNA-specific exonuclease 394585 recJ 4059940 recJ Lawsonia intracellularis PHE/MN1-00 single-stranded DNA-specific exonuclease YP_594690.1 392879 D 363253 CDS YP_594691.1 94986758 4060027 complement(394647..395873) 1 NC_008011.1 Xaa-Pro aminopeptidase 395873 pepP 4060027 pepP Lawsonia intracellularis PHE/MN1-00 Xaa-Pro aminopeptidase YP_594691.1 394647 R 363253 CDS YP_594692.1 94986759 4060295 396014..396430 1 NC_008011.1 CoA-binding protein 396430 4060295 LI0315 Lawsonia intracellularis PHE/MN1-00 CoA-binding protein YP_594692.1 396014 D 363253 CDS YP_594693.1 94986760 4060296 396615..397526 1 NC_008011.1 DnaJ-class molecular chaperone 397526 4060296 LI0316 Lawsonia intracellularis PHE/MN1-00 DnaJ-class molecular chaperone YP_594693.1 396615 D 363253 CDS YP_594694.1 94986761 4060297 397583..398272 1 NC_008011.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 398272 4060297 LI0317 Lawsonia intracellularis PHE/MN1-00 adenylate kinase YP_594694.1 397583 D 363253 CDS YP_594695.1 94986762 4060298 complement(398358..399626) 1 NC_008011.1 hypothetical protein 399626 4060298 LI0318 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594695.1 398358 R 363253 CDS YP_594696.1 94986763 4060299 complement(399629..400849) 1 NC_008011.1 ADP-heptose:LPS heptosyltransferase 400849 4060299 LI0319 Lawsonia intracellularis PHE/MN1-00 ADP-heptose:LPS heptosyltransferase YP_594696.1 399629 R 363253 CDS YP_594697.1 94986764 4060442 401285..401962 1 NC_008011.1 siroheme synthase 401962 cysG 4060442 cysG Lawsonia intracellularis PHE/MN1-00 siroheme synthase YP_594697.1 401285 D 363253 CDS YP_594698.1 94986765 4059946 401949..402839 1 NC_008011.1 ABC-type transport system involved in cytochrome c biogenesis, permease component 402839 resC 4059946 resC Lawsonia intracellularis PHE/MN1-00 ABC-type transport system involved in cytochrome c biogenesis, permease component YP_594698.1 401949 D 363253 CDS YP_594699.1 94986766 4060260 402814..404079 1 NC_008011.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 404079 hemA 4060260 hemA Lawsonia intracellularis PHE/MN1-00 glutamyl-tRNA reductase YP_594699.1 402814 D 363253 CDS YP_594700.1 94986767 4060300 404208..405515 1 NC_008011.1 Signal renition particle GTPase 405515 4060300 LI0323 Lawsonia intracellularis PHE/MN1-00 Signal renition particle GTPase YP_594700.1 404208 D 363253 CDS YP_594701.1 94986768 4059818 405585..406238 1 NC_008011.1 thiamine monophosphate synthase 406238 thiE 4059818 thiE Lawsonia intracellularis PHE/MN1-00 thiamine monophosphate synthase YP_594701.1 405585 D 363253 CDS YP_594702.1 94986769 4060222 complement(406369..407796) 1 NC_008011.1 NADPH-dependent glutamate synthase beta chain and related oxidoreductases 407796 gltD 4060222 gltD Lawsonia intracellularis PHE/MN1-00 NADPH-dependent glutamate synthase beta chain and related oxidoreductases YP_594702.1 406369 R 363253 CDS YP_594703.1 94986770 4060301 408049..408975 1 NC_008011.1 SAM-dependent methyltransferase 408975 4060301 LI0326 Lawsonia intracellularis PHE/MN1-00 SAM-dependent methyltransferase YP_594703.1 408049 D 363253 CDS YP_594704.1 94986771 4060302 complement(409616..410542) 1 NC_008011.1 hypothetical protein 410542 4060302 LI0327 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594704.1 409616 R 363253 CDS YP_594705.1 94986772 4060303 complement(410586..411035) 1 NC_008011.1 hypothetical protein 411035 4060303 LI0328 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594705.1 410586 R 363253 CDS YP_594706.1 94986773 4060325 411409..413466 1 NC_008011.1 Glyen debranching enzyme 413466 glgX 4060325 glgX Lawsonia intracellularis PHE/MN1-00 Glyen debranching enzyme YP_594706.1 411409 D 363253 CDS YP_594707.1 94986774 4060304 413485..414825 1 NC_008011.1 glycosyltransferase 414825 4060304 LI0330 Lawsonia intracellularis PHE/MN1-00 glycosyltransferase YP_594707.1 413485 D 363253 CDS YP_594708.1 94986775 4060347 414828..416114 1 NC_008011.1 alpha-amylase 416114 amyA 4060347 amyA Lawsonia intracellularis PHE/MN1-00 alpha-amylase YP_594708.1 414828 D 363253 CDS YP_594709.1 94986776 4060324 416124..420386 1 NC_008011.1 carbohydrate phosphorylase family protein 420386 glgP 4060324 glgP Lawsonia intracellularis PHE/MN1-00 carbohydrate phosphorylase family protein YP_594709.1 416124 D 363253 CDS YP_594710.1 94986777 4059376 complement(420460..421350) 1 NC_008011.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 421350 argB 4059376 argB Lawsonia intracellularis PHE/MN1-00 acetylglutamate kinase YP_594710.1 420460 R 363253 CDS YP_594711.1 94986778 4059689 complement(421371..422672) 1 NC_008011.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 422672 hslU 4059689 hslU Lawsonia intracellularis PHE/MN1-00 ATP-dependent protease ATP-binding subunit HslU YP_594711.1 421371 R 363253 CDS YP_594712.1 94986779 4059650 complement(422757..423464) 1 NC_008011.1 branched chain amino acid ABC transporter, ATP-binding protein 423464 livF 4059650 livF Lawsonia intracellularis PHE/MN1-00 branched chain amino acid ABC transporter, ATP-binding protein YP_594712.1 422757 R 363253 CDS YP_594713.1 94986780 4059652 complement(423517..424278) 1 NC_008011.1 branched chain amino acid ABC transporter, ATP-binding protein 424278 livG 4059652 livG Lawsonia intracellularis PHE/MN1-00 branched chain amino acid ABC transporter, ATP-binding protein YP_594713.1 423517 R 363253 CDS YP_594714.1 94986781 4059656 complement(424288..425274) 1 NC_008011.1 branched chain amino acid ABC transporter, permease 425274 livM 4059656 livM Lawsonia intracellularis PHE/MN1-00 branched chain amino acid ABC transporter, permease YP_594714.1 424288 R 363253 CDS YP_594715.1 94986782 4059654 complement(425271..426173) 1 NC_008011.1 branched chain amino acid ABC transporter, permease 426173 livH 4059654 livH Lawsonia intracellularis PHE/MN1-00 branched chain amino acid ABC transporter, permease YP_594715.1 425271 R 363253 CDS YP_594716.1 94986783 4060305 complement(426224..427348) 1 NC_008011.1 ABC-type branched-chain amino acid transport systems, periplasmic component 427348 4060305 LI0339 Lawsonia intracellularis PHE/MN1-00 ABC-type branched-chain amino acid transport systems, periplasmic component YP_594716.1 426224 R 363253 CDS YP_594717.1 94986784 4060306 427714..428691 1 NC_008011.1 hypothetical protein 428691 4060306 LI0340 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594717.1 427714 D 363253 CDS YP_594718.1 94986785 4059415 428956..429660 1 NC_008011.1 hypothetical protein 429660 4059415 LI0341 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594718.1 428956 D 363253 CDS YP_594719.1 94986786 4059644 429818..430519 1 NC_008011.1 Rossmann fold nucleotide-binding protein 430519 leuB 4059644 leuB Lawsonia intracellularis PHE/MN1-00 Rossmann fold nucleotide-binding protein YP_594719.1 429818 D 363253 CDS YP_594720.1 94986787 4060431 430612..431100 1 NC_008011.1 cytosine/adenosine deaminases 431100 codA 4060431 codA Lawsonia intracellularis PHE/MN1-00 cytosine/adenosine deaminases YP_594720.1 430612 D 363253 CDS YP_594721.1 94986788 4059416 431319..431606 1 NC_008011.1 hypothetical protein 431606 4059416 LI0344 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594721.1 431319 D 363253 CDS YP_594722.1 94986789 4059417 431805..432596 1 NC_008011.1 SAM-dependent methyltransferases 432596 4059417 LI0345 Lawsonia intracellularis PHE/MN1-00 SAM-dependent methyltransferases YP_594722.1 431805 D 363253 CDS YP_594723.1 94986790 4059692 complement(433193..434617) 1 NC_008011.1 trypsin domain/PDZ domain-containing protein 434617 htrA 4059692 htrA Lawsonia intracellularis PHE/MN1-00 trypsin domain/PDZ domain-containing protein YP_594723.1 433193 R 363253 CDS YP_594724.1 94986791 4059721 complement(434818..437232) 1 NC_008011.1 flagellar hook protein FlgE 437232 flgE 4059721 flgE Lawsonia intracellularis PHE/MN1-00 flagellar hook protein FlgE YP_594724.1 434818 R 363253 CDS YP_594725.1 94986792 4059722 complement(437383..438891) 1 NC_008011.1 flagellar hook protein FlgE 438891 flgE 4059722 flgE Lawsonia intracellularis PHE/MN1-00 flagellar hook protein FlgE YP_594725.1 437383 R 363253 CDS YP_594726.1 94986793 4059991 439256..440152 1 NC_008011.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 440152 purC 4059991 purC Lawsonia intracellularis PHE/MN1-00 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_594726.1 439256 D 363253 CDS YP_594727.1 94986794 4059306 440193..440957 1 NC_008011.1 enoyl-ACP reductase 440957 fabI 4059306 fabI Lawsonia intracellularis PHE/MN1-00 enoyl-ACP reductase YP_594727.1 440193 D 363253 CDS YP_594728.1 94986795 4060146 441137..442456 1 NC_008011.1 malate dehydrogenase 442456 mdh 4060146 mdh Lawsonia intracellularis PHE/MN1-00 malate dehydrogenase YP_594728.1 441137 D 363253 CDS YP_594729.1 94986796 4059418 442654..442971 1 NC_008011.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 442971 rpsF 4059418 rpsF Lawsonia intracellularis PHE/MN1-00 30S ribosomal protein S6 YP_594729.1 442654 D 363253 CDS YP_594730.1 94986797 4059881 443247..443768 1 NC_008011.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 443768 rplI 4059881 rplI Lawsonia intracellularis PHE/MN1-00 50S ribosomal protein L9 YP_594730.1 443247 D 363253 CDS YP_594731.1 94986798 4059943 443830..445194 1 NC_008011.1 replicative DNA helicase 445194 recQ 4059943 recQ Lawsonia intracellularis PHE/MN1-00 replicative DNA helicase YP_594731.1 443830 D 363253 CDS YP_594732.1 94986799 4059419 complement(445449..446039) 1 NC_008011.1 rRNA methylases 446039 4059419 LI0355 Lawsonia intracellularis PHE/MN1-00 rRNA methylases YP_594732.1 445449 R 363253 CDS YP_594733.1 94986800 4059420 complement(446089..448086) 1 NC_008011.1 ABC transporter ATPase 448086 4059420 LI0356 Lawsonia intracellularis PHE/MN1-00 ABC transporter ATPase YP_594733.1 446089 R 363253 CDS YP_594734.1 94986801 4060023 complement(448090..448959) 1 NC_008011.1 protein-L-isoaspartate carboxylmethyltransferase 448959 pcm 4060023 pcm Lawsonia intracellularis PHE/MN1-00 protein-L-isoaspartate carboxylmethyltransferase YP_594734.1 448090 R 363253 CDS YP_594735.1 94986802 4059421 449124..451136 1 NC_008011.1 asmA protein 451136 4059421 LI0358 Lawsonia intracellularis PHE/MN1-00 asmA protein YP_594735.1 449124 D 363253 CDS YP_594736.1 94986803 4060117 complement(451158..452531) 1 NC_008011.1 Mg2+/Co2+ transporter 452531 mgtE 4060117 mgtE Lawsonia intracellularis PHE/MN1-00 Mg2+/Co2+ transporter YP_594736.1 451158 R 363253 CDS YP_594737.1 94986804 4060089 452761..453651 1 NC_008011.1 nicotinate-nucleotide pyrophosphorylase 453651 nadC 4060089 nadC Lawsonia intracellularis PHE/MN1-00 nicotinate-nucleotide pyrophosphorylase YP_594737.1 452761 D 363253 CDS YP_594738.1 94986805 4059422 453648..454703 1 NC_008011.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 454703 4059422 LI0361 Lawsonia intracellularis PHE/MN1-00 quinolinate synthetase YP_594738.1 453648 D 363253 CDS YP_594739.1 94986806 4060088 454752..456335 1 NC_008011.1 aspartate oxidase 456335 nadB 4060088 nadB Lawsonia intracellularis PHE/MN1-00 aspartate oxidase YP_594739.1 454752 D 363253 CDS YP_594740.1 94986807 4059423 complement(456390..456695) 1 NC_008011.1 integral membrane protein 456695 4059423 LI0363 Lawsonia intracellularis PHE/MN1-00 integral membrane protein YP_594740.1 456390 R 363253 CDS YP_594741.1 94986808 4060251 complement(456801..457475) 1 NC_008011.1 phosphatases 457475 gph 4060251 gph Lawsonia intracellularis PHE/MN1-00 phosphatases YP_594741.1 456801 R 363253 CDS YP_594742.1 94986809 4059424 complement(457964..458686) 1 NC_008011.1 DNA uptake lipoprotein 458686 4059424 LI0365 Lawsonia intracellularis PHE/MN1-00 DNA uptake lipoprotein YP_594742.1 457964 R 363253 CDS YP_594743.1 94986810 4059503 complement(458692..459618) 1 NC_008011.1 thioredoxin reductase 459618 trxB 4059503 trxB Lawsonia intracellularis PHE/MN1-00 thioredoxin reductase YP_594743.1 458692 R 363253 CDS YP_594744.1 94986811 4059502 complement(459615..459938) 1 NC_008011.1 Thiol-disulfide isomerase and thioredoxins 459938 trxA 4059502 trxA Lawsonia intracellularis PHE/MN1-00 Thiol-disulfide isomerase and thioredoxins YP_594744.1 459615 R 363253 CDS YP_594745.1 94986812 4059623 complement(460064..461131) 1 NC_008011.1 metal-dependent proteases with chaperone activity 461131 ygjD 4059623 ygjD Lawsonia intracellularis PHE/MN1-00 metal-dependent proteases with chaperone activity YP_594745.1 460064 R 363253 CDS YP_594746.1 94986813 4059309 complement(461235..462242) 1 NC_008011.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 462242 fbp 4059309 fbp Lawsonia intracellularis PHE/MN1-00 fructose-1,6-bisphosphatase YP_594746.1 461235 R 363253 CDS YP_594747.1 94986814 4059425 complement(462356..463225) 1 NC_008011.1 hypothetical protein 463225 4059425 LI0370 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594747.1 462356 R 363253 CDS YP_594748.1 94986815 4059426 complement(463255..464136) 1 NC_008011.1 hypothetical protein 464136 4059426 LI0371 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594748.1 463255 R 363253 CDS YP_594749.1 94986816 4059427 complement(464159..464470) 1 NC_008011.1 hypothetical protein 464470 4059427 LI0372 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594749.1 464159 R 363253 CDS YP_594750.1 94986817 4059996 complement(464482..465042) 1 NC_008011.1 phosphatidylglycerophosphate synthase 465042 pgsA 4059996 pgsA Lawsonia intracellularis PHE/MN1-00 phosphatidylglycerophosphate synthase YP_594750.1 464482 R 363253 CDS YP_594751.1 94986818 4059428 complement(465190..466008) 1 NC_008011.1 chromosome partitioning ATPase 466008 4059428 LI0374 Lawsonia intracellularis PHE/MN1-00 chromosome partitioning ATPase YP_594751.1 465190 R 363253 CDS YP_594752.1 94986819 4060024 complement(466089..466769) 1 NC_008011.1 protein-L-isoaspartate carboxylmethyltransferase 466769 pcm 4060024 pcm Lawsonia intracellularis PHE/MN1-00 protein-L-isoaspartate carboxylmethyltransferase YP_594752.1 466089 R 363253 CDS YP_594753.1 94986820 4059429 467194..468507 1 NC_008011.1 membrane proteins related to metalloendopeptidases 468507 4059429 LI0376 Lawsonia intracellularis PHE/MN1-00 membrane proteins related to metalloendopeptidases YP_594753.1 467194 D 363253 CDS YP_594754.1 94986821 4059846 468756..469631 1 NC_008011.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 469631 rpsB 4059846 rpsB Lawsonia intracellularis PHE/MN1-00 30S ribosomal protein S2 YP_594754.1 468756 D 363253 CDS YP_594755.1 94986822 4059504 469657..470541 1 NC_008011.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 470541 tsf 4059504 tsf Lawsonia intracellularis PHE/MN1-00 elongation factor Ts YP_594755.1 469657 D 363253 CDS YP_594756.1 94986823 4060315 470643..471623 1 NC_008011.1 nucleoside-diphosphate-sugar epimerases 471623 galE 4060315 galE Lawsonia intracellularis PHE/MN1-00 nucleoside-diphosphate-sugar epimerases YP_594756.1 470643 D 363253 CDS YP_594757.1 94986824 4059430 471627..472781 1 NC_008011.1 cell wall biogenesis regulatory protein 472781 4059430 LI0380 Lawsonia intracellularis PHE/MN1-00 cell wall biogenesis regulatory protein YP_594757.1 471627 D 363253 CDS YP_594758.1 94986825 4059647 472788..473591 1 NC_008011.1 cell wall biosynthesis glycosyltransferase 473591 lgtF 4059647 lgtF Lawsonia intracellularis PHE/MN1-00 cell wall biosynthesis glycosyltransferase YP_594758.1 472788 D 363253 CDS YP_594759.1 94986826 4059971 473612..474328 1 NC_008011.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 474328 pyrH 4059971 pyrH Lawsonia intracellularis PHE/MN1-00 uridylate kinase YP_594759.1 473612 D 363253 CDS YP_594760.1 94986827 4059625 474332..474898 1 NC_008011.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 474898 frr 4059625 frr Lawsonia intracellularis PHE/MN1-00 ribosome recycling factor YP_594760.1 474332 D 363253 CDS YP_594761.1 94986828 4059616 474934..475656 1 NC_008011.1 UDP pyrophosphate synthase 475656 yaeS 4059616 yaeS Lawsonia intracellularis PHE/MN1-00 UDP pyrophosphate synthase YP_594761.1 474934 D 363253 CDS YP_594762.1 94986829 4060413 475653..476450 1 NC_008011.1 CDP-diglyceride synthetase 476450 cdsA 4060413 cdsA Lawsonia intracellularis PHE/MN1-00 CDP-diglyceride synthetase YP_594762.1 475653 D 363253 CDS YP_594763.1 94986830 4059299 476513..477721 1 NC_008011.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 477721 dxr 4059299 dxr Lawsonia intracellularis PHE/MN1-00 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_594763.1 476513 D 363253 CDS YP_594764.1 94986831 4059431 477721..478845 1 NC_008011.1 membrane-associated Zn-dependent proteases 1 478845 4059431 LI0387 Lawsonia intracellularis PHE/MN1-00 membrane-associated Zn-dependent proteases 1 YP_594764.1 477721 D 363253 CDS YP_594765.1 94986832 4059432 478842..479636 1 NC_008011.1 hypothetical protein 479636 4059432 LI0388 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594765.1 478842 D 363253 CDS YP_594766.1 94986833 4059433 480542..481426 1 NC_008011.1 modification methylase BepI (cytosine-specific methyltransferase BepI) 481426 4059433 LI0389 Lawsonia intracellularis PHE/MN1-00 modification methylase BepI (cytosine-specific methyltransferase BepI) YP_594766.1 480542 D 363253 CDS YP_594767.1 94986834 4059982 complement(481800..483527) 1 NC_008011.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 483527 proS 4059982 proS Lawsonia intracellularis PHE/MN1-00 prolyl-tRNA synthetase YP_594767.1 481800 R 363253 CDS YP_594768.1 94986835 4059434 complement(483648..484544) 1 NC_008011.1 Fe-S oxidoreductase 484544 4059434 LI0391 Lawsonia intracellularis PHE/MN1-00 Fe-S oxidoreductase YP_594768.1 483648 R 363253 CDS YP_594769.1 94986836 4060129 484633..485673 1 NC_008011.1 functions in MreBCD complex in some organisms; rod shape-determining protein MreB 485673 mreB 4060129 mreB Lawsonia intracellularis PHE/MN1-00 rod shape-determining protein MreB YP_594769.1 484633 D 363253 CDS YP_594770.1 94986837 4060072 485787..486668 1 NC_008011.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 486668 mreC 4060072 mreC Lawsonia intracellularis PHE/MN1-00 rod shape-determining protein MreC YP_594770.1 485787 D 363253 CDS YP_594771.1 94986838 4060151 486665..487135 1 NC_008011.1 hypothetical protein 487135 4060151 LI0394 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594771.1 486665 D 363253 CDS YP_594772.1 94986839 4060152 487119..488912 1 NC_008011.1 cell division protein FtsI/penicillin-binding protein 2 488912 4060152 LI0395 Lawsonia intracellularis PHE/MN1-00 cell division protein FtsI/penicillin-binding protein 2 YP_594772.1 487119 D 363253 CDS YP_594773.1 94986840 4059911 488937..490052 1 NC_008011.1 rod shape-determining protein RodA 490052 rodA 4059911 rodA Lawsonia intracellularis PHE/MN1-00 rod shape-determining protein RodA YP_594773.1 488937 D 363253 CDS YP_594774.1 94986841 4060153 490077..490424 1 NC_008011.1 cell shape determination protein CcmA 490424 4060153 LI0397 Lawsonia intracellularis PHE/MN1-00 cell shape determination protein CcmA YP_594774.1 490077 D 363253 CDS YP_594775.1 94986842 4060154 490519..490941 1 NC_008011.1 F0F1-type ATP synthase, subunit b 490941 4060154 LI0398 Lawsonia intracellularis PHE/MN1-00 F0F1-type ATP synthase, subunit b YP_594775.1 490519 D 363253 CDS YP_594776.1 94986843 4060391 <490959..491537 1 NC_008011.1 F0F1-type ATP synthase, subunit b 491537 atpF 4060391 atpF Lawsonia intracellularis PHE/MN1-00 F0F1-type ATP synthase, subunit b YP_594776.1 <490959 D 363253 CDS YP_594777.1 94986844 4060390 491534..492100 1 NC_008011.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 492100 atpE 4060390 atpE Lawsonia intracellularis PHE/MN1-00 F0F1 ATP synthase subunit delta YP_594777.1 491534 D 363253 CDS YP_594778.1 94986845 4060389 492090..493610 1 NC_008011.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 493610 atpD 4060389 atpD Lawsonia intracellularis PHE/MN1-00 F0F1 ATP synthase subunit alpha YP_594778.1 492090 D 363253 CDS YP_594779.1 94986846 4059394 493615..494484 1 NC_008011.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 494484 atpC 4059394 atpC Lawsonia intracellularis PHE/MN1-00 F0F1 ATP synthase subunit gamma YP_594779.1 493615 D 363253 CDS YP_594780.1 94986847 4059393 494508..495923 1 NC_008011.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 495923 atpB 4059393 atpB Lawsonia intracellularis PHE/MN1-00 F0F1 ATP synthase subunit beta YP_594780.1 494508 D 363253 CDS YP_594781.1 94986848 4059391 495934..496335 1 NC_008011.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the epsilon subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit epsilon 496335 atpC 4059391 atpC Lawsonia intracellularis PHE/MN1-00 F0F1 ATP synthase subunit epsilon YP_594781.1 495934 D 363253 CDS YP_594782.1 94986849 4059614 496471..497913 1 NC_008011.1 exonuclease VII, large subunit 497913 xseA 4059614 xseA Lawsonia intracellularis PHE/MN1-00 exonuclease VII, large subunit YP_594782.1 496471 D 363253 CDS YP_594783.1 94986850 4060155 497938..498807 1 NC_008011.1 membrane proteins related to metalloendopeptidases 498807 4060155 LI0406 Lawsonia intracellularis PHE/MN1-00 membrane proteins related to metalloendopeptidases YP_594783.1 497938 D 363253 CDS YP_594784.1 94986851 4060156 499089..499991 1 NC_008011.1 geranylgeranyl pyrophosphate synthase 499991 4060156 LI0407 Lawsonia intracellularis PHE/MN1-00 geranylgeranyl pyrophosphate synthase YP_594784.1 499089 D 363253 CDS YP_594785.1 94986852 4060386 500065..501978 1 NC_008011.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 501978 dsx 4060386 dsx Lawsonia intracellularis PHE/MN1-00 1-deoxy-D-xylulose-5-phosphate synthase YP_594785.1 500065 D 363253 CDS YP_594786.1 94986853 4060157 complement(502001..503026) 1 NC_008011.1 ATPase 503026 4060157 LI0409 Lawsonia intracellularis PHE/MN1-00 ATPase YP_594786.1 502001 R 363253 CDS YP_594787.1 94986854 4059494 complement(504438..505217) 1 NC_008011.1 bifunctional tryptophan synthase TRPB 505217 trpA 4059494 trpA Lawsonia intracellularis PHE/MN1-00 bifunctional tryptophan synthase TRPB YP_594787.1 504438 R 363253 CDS YP_594788.1 94986855 4059495 complement(505228..506397) 1 NC_008011.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 506397 trpB 4059495 trpB Lawsonia intracellularis PHE/MN1-00 tryptophan synthase subunit beta YP_594788.1 505228 R 363253 CDS YP_594789.1 94986856 4059498 complement(506387..507004) 1 NC_008011.1 phosphoribosyl anthranilate isomerase 507004 trpF 4059498 trpF Lawsonia intracellularis PHE/MN1-00 phosphoribosyl anthranilate isomerase YP_594789.1 506387 R 363253 CDS YP_594790.1 94986857 4059496 complement(506982..507704) 1 NC_008011.1 indole-3-glycerol phosphate synthase 507704 trpC_2 4059496 trpC_2 Lawsonia intracellularis PHE/MN1-00 indole-3-glycerol phosphate synthase YP_594790.1 506982 R 363253 CDS YP_594791.1 94986858 4059497 complement(507758..508744) 1 NC_008011.1 anthranilate phosphoribosyltransferase 508744 trpD 4059497 trpD Lawsonia intracellularis PHE/MN1-00 anthranilate phosphoribosyltransferase YP_594791.1 507758 R 363253 CDS YP_594792.1 94986859 4060158 complement(508741..509877) 1 NC_008011.1 kynureninase (kyurenine hydrolase) 509877 4060158 LI0415 Lawsonia intracellularis PHE/MN1-00 kynureninase (kyurenine hydrolase) YP_594792.1 508741 R 363253 CDS YP_594793.1 94986860 4060159 complement(509880..510698) 1 NC_008011.1 ABC transporter permease 510698 4060159 LI0416 Lawsonia intracellularis PHE/MN1-00 ABC transporter permease YP_594793.1 509880 R 363253 CDS YP_594794.1 94986861 4060160 complement(510688..511422) 1 NC_008011.1 ABC transporter ATP-binding protein 511422 4060160 LI0417 Lawsonia intracellularis PHE/MN1-00 ABC transporter ATP-binding protein YP_594794.1 510688 R 363253 CDS YP_594795.1 94986862 4060161 complement(511426..512397) 1 NC_008011.1 hypothetical protein 512397 4060161 LI0418 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594795.1 511426 R 363253 CDS YP_594796.1 94986863 4060162 <514084..>514919 1 NC_008011.1 short chain dehydrogenase >514919 4060162 LI0419 Lawsonia intracellularis PHE/MN1-00 short chain dehydrogenase YP_594796.1 <514084 D 363253 CDS YP_594797.1 94986864 4060396 complement(514967..515935) 1 NC_008011.1 biotin synthase 515935 bioB 4060396 bioB Lawsonia intracellularis PHE/MN1-00 biotin synthase YP_594797.1 514967 R 363253 CDS YP_594798.1 94986865 4060399 515952..517097 1 NC_008011.1 7-keto-8-aminopelargonate synthetase and related enzymes 517097 bioF 4060399 bioF Lawsonia intracellularis PHE/MN1-00 7-keto-8-aminopelargonate synthetase and related enzymes YP_594798.1 515952 D 363253 CDS YP_594799.1 94986866 4060163 517094..517732 1 NC_008011.1 hypothetical protein 517732 4060163 LI0422 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594799.1 517094 D 363253 CDS YP_594800.1 94986867 4060397 517752..518495 1 NC_008011.1 ubiE/COQ5 methyltransferase family protein 518495 bioC 4060397 bioC Lawsonia intracellularis PHE/MN1-00 ubiE/COQ5 methyltransferase family protein YP_594800.1 517752 D 363253 CDS YP_594801.1 94986868 4060398 518495..519106 1 NC_008011.1 dethiobiotin synthetase 519106 bioD 4060398 bioD Lawsonia intracellularis PHE/MN1-00 dethiobiotin synthetase YP_594801.1 518495 D 363253 CDS YP_594802.1 94986869 4060395 519110..520387 1 NC_008011.1 adenosylmethionine-8-amino-7-oxononanoate aminotransferase 520387 bioA 4060395 bioA Lawsonia intracellularis PHE/MN1-00 adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_594802.1 519110 D 363253 CDS YP_594803.1 94986870 4060164 complement(520457..521032) 1 NC_008011.1 hypothetical protein 521032 4060164 LI0427 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594803.1 520457 R 363253 CDS YP_594804.1 94986871 4059962 522545..523912 1 NC_008011.1 sodium-dependent transporter 523912 putP 4059962 putP Lawsonia intracellularis PHE/MN1-00 sodium-dependent transporter YP_594804.1 522545 D 363253 CDS YP_594805.1 94986872 4060264 complement(524004..525074) 1 NC_008011.1 coproporphyrinogen III oxidase-like protein 525074 hemN 4060264 hemN Lawsonia intracellularis PHE/MN1-00 coproporphyrinogen III oxidase-like protein YP_594805.1 524004 R 363253 CDS YP_594806.1 94986873 4060165 525142..525582 1 NC_008011.1 histidine triad nucleotide-binding protein 525582 4060165 LI0430 Lawsonia intracellularis PHE/MN1-00 histidine triad nucleotide-binding protein YP_594806.1 525142 D 363253 CDS YP_594807.1 94986874 4060268 525657..525947 1 NC_008011.1 nucleoid DNA-binding protein 525947 himA 4060268 himA Lawsonia intracellularis PHE/MN1-00 nucleoid DNA-binding protein YP_594807.1 525657 D 363253 CDS YP_594808.1 94986875 4060166 complement(526092..526742) 1 NC_008011.1 S-adenosylmethionine-dependent methyltransferase involved in cell division 526742 4060166 LI0432 Lawsonia intracellularis PHE/MN1-00 S-adenosylmethionine-dependent methyltransferase involved in cell division YP_594808.1 526092 R 363253 CDS YP_594809.1 94986876 4060384 complement(527009..528847) 1 NC_008011.1 hypothetical protein 528847 dsbD 4060384 dsbD Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594809.1 527009 R 363253 CDS YP_594810.1 94986877 4060167 complement(529148..530338) 1 NC_008011.1 glycosyltransferase 530338 4060167 LI0434 Lawsonia intracellularis PHE/MN1-00 glycosyltransferase YP_594810.1 529148 R 363253 CDS YP_594811.1 94986878 4059387 530484..531716 1 NC_008011.1 catalyzes the interconversion of tetrahydrodipicolinate and L,L-diaminopimelate in lysine biosynthesis; L,L-diaminopimelate aminotransferase 531716 aspC 4059387 aspC Lawsonia intracellularis PHE/MN1-00 L,L-diaminopimelate aminotransferase YP_594811.1 530484 D 363253 CDS YP_594812.1 94986879 4060168 complement(531796..532644) 1 NC_008011.1 PhyA2 532644 4060168 LI0436 Lawsonia intracellularis PHE/MN1-00 PhyA2 YP_594812.1 531796 R 363253 CDS YP_594813.1 94986880 4060169 complement(532566..533117) 1 NC_008011.1 histidine acid phosphatase 533117 4060169 LI0437 Lawsonia intracellularis PHE/MN1-00 histidine acid phosphatase YP_594813.1 532566 R 363253 CDS YP_594814.1 94986881 4060190 complement(533368..534693) 1 NC_008011.1 PhyA2 534693 4060190 LI0438 Lawsonia intracellularis PHE/MN1-00 PhyA2 YP_594814.1 533368 R 363253 CDS YP_594815.1 94986882 4059694 535099..536355 1 NC_008011.1 hydrogenase-1 small subunit 536355 hyaA 4059694 hyaA Lawsonia intracellularis PHE/MN1-00 hydrogenase-1 small subunit YP_594815.1 535099 D 363253 CDS YP_594816.1 94986883 4059695 536370..538178 1 NC_008011.1 hydrogenase-1 large subunit 538178 hyaB 4059695 hyaB Lawsonia intracellularis PHE/MN1-00 hydrogenase-1 large subunit YP_594816.1 536370 D 363253 CDS YP_594817.1 94986884 4059696 538288..538992 1 NC_008011.1 Ni/Fe-hydrogenase 1 B-type cytochrome subunit 538992 hyaC 4059696 hyaC Lawsonia intracellularis PHE/MN1-00 Ni/Fe-hydrogenase 1 B-type cytochrome subunit YP_594817.1 538288 D 363253 CDS YP_594818.1 94986885 4059697 538995..539531 1 NC_008011.1 processing of HyaA and HyaB proteins 539531 hyaD 4059697 hyaD Lawsonia intracellularis PHE/MN1-00 processing of HyaA and HyaB proteins YP_594818.1 538995 D 363253 CDS YP_594819.1 94986886 4060191 540291..540695 1 NC_008011.1 hypothetical protein 540695 4060191 LI0443 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594819.1 540291 D 363253 CDS YP_594820.1 94986887 4060192 540700..541770 1 NC_008011.1 glycosyltransferase 541770 4060192 LI0444 Lawsonia intracellularis PHE/MN1-00 glycosyltransferase YP_594820.1 540700 D 363253 CDS YP_594821.1 94986888 4060387 complement(541891..542361) 1 NC_008011.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 542361 dtd 4060387 dtd Lawsonia intracellularis PHE/MN1-00 D-tyrosyl-tRNA(Tyr) deacylase YP_594821.1 541891 R 363253 CDS YP_594822.1 94986889 4060193 complement(542402..543601) 1 NC_008011.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase 543601 4060193 LI0446 Lawsonia intracellularis PHE/MN1-00 4-diphosphocytidyl-2C-methyl-D-erythritol synthase YP_594822.1 542402 R 363253 CDS YP_594823.1 94986890 4060194 543696..543989 1 NC_008011.1 hypothetical protein 543989 4060194 LI0447 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594823.1 543696 D 363253 CDS YP_594824.1 94986891 4060195 complement(544048..544812) 1 NC_008011.1 hypothetical protein 544812 4060195 LI0448 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594824.1 544048 R 363253 CDS YP_594825.1 94986892 4060196 complement(544847..545644) 1 NC_008011.1 hypothetical protein 545644 4060196 LI0449 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594825.1 544847 R 363253 CDS YP_594826.1 94986893 4059958 complement(545767..546591) 1 NC_008011.1 phosphoribosylformylglycinamidine synthase domain-containing protein 546591 purL 4059958 purL Lawsonia intracellularis PHE/MN1-00 phosphoribosylformylglycinamidine synthase domain-containing protein YP_594826.1 545767 R 363253 CDS YP_594827.1 94986894 4059970 546832..548484 1 NC_008011.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 548484 pyrG 4059970 pyrG Lawsonia intracellularis PHE/MN1-00 CTP synthetase YP_594827.1 546832 D 363253 CDS YP_594828.1 94986895 4059674 548515..549321 1 NC_008011.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 549321 kdsA 4059674 kdsA Lawsonia intracellularis PHE/MN1-00 2-dehydro-3-deoxyphosphooctonate aldolase YP_594828.1 548515 D 363253 CDS YP_594829.1 94986896 4060197 549318..549929 1 NC_008011.1 HAD superfamily low specificity phosphatase 549929 4060197 LI0453 Lawsonia intracellularis PHE/MN1-00 HAD superfamily low specificity phosphatase YP_594829.1 549318 D 363253 CDS YP_594830.1 94986897 4060198 550004..550549 1 NC_008011.1 hypothetical protein 550549 4060198 LI0454 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594830.1 550004 D 363253 CDS YP_594831.1 94986898 4060199 550649..551218 1 NC_008011.1 hypothetical protein 551218 4060199 LI0455 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594831.1 550649 D 363253 CDS YP_594832.1 94986899 4060200 551218..551940 1 NC_008011.1 ABC transporter ATPase 551940 4060200 LI0456 Lawsonia intracellularis PHE/MN1-00 ABC transporter ATPase YP_594832.1 551218 D 363253 CDS YP_594833.1 94986900 4059845 552086..553507 1 NC_008011.1 DNA-directed RNA polymerase specialized sigma subunit, sigma54-like protein 553507 rpoN 4059845 rpoN Lawsonia intracellularis PHE/MN1-00 DNA-directed RNA polymerase specialized sigma subunit, sigma54-like protein YP_594833.1 552086 D 363253 CDS YP_594834.1 94986901 4060201 553542..554078 1 NC_008011.1 ribosome-associated protein Y (PSrp-1) 554078 4060201 LI0458 Lawsonia intracellularis PHE/MN1-00 ribosome-associated protein Y (PSrp-1) YP_594834.1 553542 D 363253 CDS YP_594835.1 94986902 4060202 554113..555078 1 NC_008011.1 hypothetical protein 555078 4060202 LI0459 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594835.1 554113 D 363253 CDS YP_594836.1 94986903 4060203 555553..556104 1 NC_008011.1 outer membrane protein 556104 4060203 LI0460 Lawsonia intracellularis PHE/MN1-00 outer membrane protein YP_594836.1 555553 D 363253 CDS YP_594837.1 94986904 4060204 complement(556323..557819) 1 NC_008011.1 hypothetical protein 557819 4060204 LI0461 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594837.1 556323 R 363253 CDS YP_594838.1 94986905 4060224 complement(557976..559373) 1 NC_008011.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 559373 gltX 4060224 gltX Lawsonia intracellularis PHE/MN1-00 glutamyl-tRNA synthetase YP_594838.1 557976 R 363253 CDS YP_594839.1 94986906 4060205 complement(559477..560727) 1 NC_008011.1 hypothetical protein 560727 4060205 LI0463 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594839.1 559477 R 363253 CDS YP_594840.1 94986907 4059994 complement(560781..562121) 1 NC_008011.1 phosphoglycerate kinase 562121 pgk 4059994 pgk Lawsonia intracellularis PHE/MN1-00 phosphoglycerate kinase YP_594840.1 560781 R 363253 CDS YP_594841.1 94986908 4060206 562525..563409 1 NC_008011.1 hypothetical protein 563409 4060206 LI0465 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594841.1 562525 D 363253 CDS YP_594842.1 94986909 4060316 complement(563439..564431) 1 NC_008011.1 nucleoside-diphosphate-sugar epimerases 564431 galE 4060316 galE Lawsonia intracellularis PHE/MN1-00 nucleoside-diphosphate-sugar epimerases YP_594842.1 563439 R 363253 CDS YP_594843.1 94986910 4060438 complement(564532..565308) 1 NC_008011.1 carbonic anhydrase 565308 cynT 4060438 cynT Lawsonia intracellularis PHE/MN1-00 carbonic anhydrase YP_594843.1 564532 R 363253 CDS YP_594844.1 94986911 4059951 566233..567591 1 NC_008011.1 dTDP-D-glucose 4,6-dehydratase 567591 rfbB 4059951 rfbB Lawsonia intracellularis PHE/MN1-00 dTDP-D-glucose 4,6-dehydratase YP_594844.1 566233 D 363253 CDS YP_594845.1 94986912 4060207 567584..569458 1 NC_008011.1 hypothetical protein 569458 4060207 LI0469 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594845.1 567584 D 363253 CDS YP_594846.1 94986913 4060208 569852..570466 1 NC_008011.1 membrane proteins related to metalloendopeptidases 570466 4060208 LI0470 Lawsonia intracellularis PHE/MN1-00 membrane proteins related to metalloendopeptidases YP_594846.1 569852 D 363253 CDS YP_594847.1 94986914 4060209 570504..571607 1 NC_008011.1 xylanase/chitin deacetylase 571607 4060209 LI0471 Lawsonia intracellularis PHE/MN1-00 xylanase/chitin deacetylase YP_594847.1 570504 D 363253 CDS YP_594848.1 94986915 4059512 complement(571638..572678) 1 NC_008011.1 permease 572678 4059512 LI0472 Lawsonia intracellularis PHE/MN1-00 permease YP_594848.1 571638 R 363253 CDS YP_594849.1 94986916 4059513 complement(573983..577249) 1 NC_008011.1 DNA methylase 577249 4059513 LI0473 Lawsonia intracellularis PHE/MN1-00 DNA methylase YP_594849.1 573983 R 363253 CDS YP_594850.1 94986917 4059514 complement(579345..579749) 1 NC_008011.1 tellurite resistance 579749 4059514 LI0474 Lawsonia intracellularis PHE/MN1-00 tellurite resistance YP_594850.1 579345 R 363253 CDS YP_594851.1 94986918 4059515 complement(<579945..580343) 1 NC_008011.1 hypothetical protein 580343 4059515 LI0475 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594851.1 <579945 R 363253 CDS YP_594852.1 94986919 4060062 581215..583965 1 NC_008011.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 583965 nrdA 4060062 nrdA Lawsonia intracellularis PHE/MN1-00 ribonucleotide-diphosphate reductase subunit alpha YP_594852.1 581215 D 363253 CDS YP_594853.1 94986920 4060063 584106..585107 1 NC_008011.1 ribonucleotide reductase, beta subunit 585107 nrdB 4060063 nrdB Lawsonia intracellularis PHE/MN1-00 ribonucleotide reductase, beta subunit YP_594853.1 584106 D 363253 CDS YP_594854.1 94986921 4059516 complement(585484..586632) 1 NC_008011.1 cytosine deaminase-like protein 586632 4059516 LI0478 Lawsonia intracellularis PHE/MN1-00 cytosine deaminase-like protein YP_594854.1 585484 R 363253 CDS YP_594855.1 94986922 4059517 587222..588658 1 NC_008011.1 alginate O-acetylation protein 588658 4059517 LI0479 Lawsonia intracellularis PHE/MN1-00 alginate O-acetylation protein YP_594855.1 587222 D 363253 CDS YP_594856.1 94986923 4059518 588676..590637 1 NC_008011.1 esterase MesA 590637 4059518 LI0480 Lawsonia intracellularis PHE/MN1-00 esterase MesA YP_594856.1 588676 D 363253 CDS YP_594857.1 94986924 4059519 590701..591078 1 NC_008011.1 hypothetical protein 591078 4059519 LI0481 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594857.1 590701 D 363253 CDS YP_594858.1 94986925 4060123 591277..592125 1 NC_008011.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA 592125 motA 4060123 motA Lawsonia intracellularis PHE/MN1-00 flagellar motor protein MotA YP_594858.1 591277 D 363253 CDS YP_594859.1 94986926 4060125 592170..592883 1 NC_008011.1 flagellar motor protein 592883 motB 4060125 motB Lawsonia intracellularis PHE/MN1-00 flagellar motor protein YP_594859.1 592170 D 363253 CDS YP_594860.1 94986927 4059520 complement(592910..594616) 1 NC_008011.1 hypothetical protein 594616 4059520 LI0484 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594860.1 592910 R 363253 CDS YP_594861.1 94986928 4059521 complement(594907..596061) 1 NC_008011.1 major facilitator superfamily permease 596061 4059521 LI0485 Lawsonia intracellularis PHE/MN1-00 major facilitator superfamily permease YP_594861.1 594907 R 363253 CDS YP_594862.1 94986929 4060124 596408..597160 1 NC_008011.1 flagellar motor component 597160 motA 4060124 motA Lawsonia intracellularis PHE/MN1-00 flagellar motor component YP_594862.1 596408 D 363253 CDS YP_594863.1 94986930 4060126 597267..597887 1 NC_008011.1 flagellar motor protein 597887 motB 4060126 motB Lawsonia intracellularis PHE/MN1-00 flagellar motor protein YP_594863.1 597267 D 363253 CDS YP_594864.1 94986931 4060338 598269..599687 1 NC_008011.1 biotin carboxylase 599687 accC 4060338 accC Lawsonia intracellularis PHE/MN1-00 biotin carboxylase YP_594864.1 598269 D 363253 CDS YP_594865.1 94986932 4059522 599700..601946 1 NC_008011.1 Acetyl-CoA carboxylase alpha subunit 601946 4059522 LI0489 Lawsonia intracellularis PHE/MN1-00 Acetyl-CoA carboxylase alpha subunit YP_594865.1 599700 D 363253 CDS YP_594866.1 94986933 4059523 601994..602644 1 NC_008011.1 hypothetical protein 602644 4059523 LI0490 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594866.1 601994 D 363253 CDS YP_594867.1 94986934 4059524 602649..602993 1 NC_008011.1 hypothetical protein 602993 4059524 LI0491 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594867.1 602649 D 363253 CDS YP_594868.1 94986935 4059525 603031..603486 1 NC_008011.1 single-stranded DNA-binding protein 603486 4059525 LI0492 Lawsonia intracellularis PHE/MN1-00 single-stranded DNA-binding protein YP_594868.1 603031 D 363253 CDS YP_594869.1 94986936 4060217 complement(603604..605301) 1 NC_008011.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 605301 glnS 4060217 glnS Lawsonia intracellularis PHE/MN1-00 glutaminyl-tRNA synthetase YP_594869.1 603604 R 363253 CDS YP_594870.1 94986937 4059526 complement(605340..605717) 1 NC_008011.1 hypothetical protein 605717 4059526 LI0494 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594870.1 605340 R 363253 CDS YP_594871.1 94986938 4059527 605999..607135 1 NC_008011.1 glycosyltransferase 607135 4059527 LI0495 Lawsonia intracellularis PHE/MN1-00 glycosyltransferase YP_594871.1 605999 D 363253 CDS YP_594872.1 94986939 4059528 607449..608588 1 NC_008011.1 branched chain amino acid ABC transporter, periplasmic amino acid-binding protein 608588 4059528 LI0496 Lawsonia intracellularis PHE/MN1-00 branched chain amino acid ABC transporter, periplasmic amino acid-binding protein YP_594872.1 607449 D 363253 CDS YP_594873.1 94986940 4059655 608669..609562 1 NC_008011.1 branched chain amino acid ABC transporter, permease 609562 livH 4059655 livH Lawsonia intracellularis PHE/MN1-00 branched chain amino acid ABC transporter, permease YP_594873.1 608669 D 363253 CDS YP_594874.1 94986941 4059657 609559..610602 1 NC_008011.1 branched chain amino acid ABC transporter, permease 610602 livM 4059657 livM Lawsonia intracellularis PHE/MN1-00 branched chain amino acid ABC transporter, permease YP_594874.1 609559 D 363253 CDS YP_594875.1 94986942 4059653 610599..611405 1 NC_008011.1 branched chain amino acid ABC transporter, ATP-binding protein 611405 livG 4059653 livG Lawsonia intracellularis PHE/MN1-00 branched chain amino acid ABC transporter, ATP-binding protein YP_594875.1 610599 D 363253 CDS YP_594876.1 94986943 4059651 611398..612120 1 NC_008011.1 branched chain amino acid ABC transporter, ATP-binding protein 612120 livF 4059651 livF Lawsonia intracellularis PHE/MN1-00 branched chain amino acid ABC transporter, ATP-binding protein YP_594876.1 611398 D 363253 CDS YP_594877.1 94986944 4060011 612389..614464 1 NC_008011.1 pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient; membrane-bound proton-translocating pyrophosphatase 614464 hppA 4060011 hppA Lawsonia intracellularis PHE/MN1-00 membrane-bound proton-translocating pyrophosphatase YP_594877.1 612389 D 363253 CDS YP_594878.1 94986945 4060020 complement(614756..615940) 1 NC_008011.1 periplasmic solute-binding protein 615940 pabC 4060020 pabC Lawsonia intracellularis PHE/MN1-00 periplasmic solute-binding protein YP_594878.1 614756 R 363253 CDS YP_594879.1 94986946 4059529 complement(615937..616365) 1 NC_008011.1 endonuclease 616365 4059529 LI0503 Lawsonia intracellularis PHE/MN1-00 endonuclease YP_594879.1 615937 R 363253 CDS YP_594880.1 94986947 4059820 617036..617818 1 NC_008011.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 617818 thiG 4059820 thiG Lawsonia intracellularis PHE/MN1-00 thiazole synthase YP_594880.1 617036 D 363253 CDS YP_594881.1 94986948 4059821 617868..618959 1 NC_008011.1 thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes 618959 thiH 4059821 thiH Lawsonia intracellularis PHE/MN1-00 thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes YP_594881.1 617868 D 363253 CDS YP_594882.1 94986949 4059819 618969..619589 1 NC_008011.1 catalyzes the adenylation of ThiS which is involved in the formation of 5-methyl-4-(beta-hydroxyethyl)thiazole phosphate; thiamine biosynthesis protein ThiF 619589 thiF 4059819 thiF Lawsonia intracellularis PHE/MN1-00 thiamine biosynthesis protein ThiF YP_594882.1 618969 D 363253 CDS YP_594883.1 94986950 4059530 complement(619631..620785) 1 NC_008011.1 hypothetical protein 620785 4059530 LI0507 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594883.1 619631 R 363253 CDS YP_594884.1 94986951 4060092 complement(620873..622246) 1 NC_008011.1 multidrug resistance protein norM 622246 4060092 LI0508 Lawsonia intracellularis PHE/MN1-00 multidrug resistance protein norM YP_594884.1 620873 R 363253 CDS YP_594885.1 94986952 4060093 complement(622366..623799) 1 NC_008011.1 carbon starvation protein, membrane protein 623799 4060093 LI0509 Lawsonia intracellularis PHE/MN1-00 carbon starvation protein, membrane protein YP_594885.1 622366 R 363253 CDS YP_594886.1 94986953 4059812 624527..625507 1 NC_008011.1 tellurium resistance protein TerC 625507 terC 4059812 terC Lawsonia intracellularis PHE/MN1-00 tellurium resistance protein TerC YP_594886.1 624527 D 363253 CDS YP_594887.1 94986954 4060094 complement(625603..626085) 1 NC_008011.1 hypothetical protein 626085 4060094 LI0511 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594887.1 625603 R 363253 CDS YP_594888.1 94986955 4060095 complement(626142..627587) 1 NC_008011.1 lipopolysaccharide synthesis sugar transferase 627587 4060095 LI0512 Lawsonia intracellularis PHE/MN1-00 lipopolysaccharide synthesis sugar transferase YP_594888.1 626142 R 363253 CDS YP_594889.1 94986956 4060096 complement(627646..628749) 1 NC_008011.1 glycosyltransferase 628749 4060096 LI0513 Lawsonia intracellularis PHE/MN1-00 glycosyltransferase YP_594889.1 627646 R 363253 CDS YP_594890.1 94986957 4060097 628999..630420 1 NC_008011.1 Na+/H+ antiporter NhaD and related arsenite permeases 630420 4060097 LI0514 Lawsonia intracellularis PHE/MN1-00 Na+/H+ antiporter NhaD and related arsenite permeases YP_594890.1 628999 D 363253 CDS YP_594891.1 94986958 4059671 630795..631769 1 NC_008011.1 geranylgeranyl pyrophosphate synthase 631769 ispB 4059671 ispB Lawsonia intracellularis PHE/MN1-00 geranylgeranyl pyrophosphate synthase YP_594891.1 630795 D 363253 CDS YP_594892.1 94986959 4059959 631796..634774 1 NC_008011.1 phosphoribosylformylglycinamidine synthase domain-containing protein 634774 purL 4059959 purL Lawsonia intracellularis PHE/MN1-00 phosphoribosylformylglycinamidine synthase domain-containing protein YP_594892.1 631796 D 363253 CDS YP_594893.1 94986960 4059844 complement(634857..636629) 1 NC_008011.1 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) 636629 rpoD 4059844 rpoD Lawsonia intracellularis PHE/MN1-00 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) YP_594893.1 634857 R 363253 CDS YP_594894.1 94986961 4060377 complement(636619..638349) 1 NC_008011.1 DNA primase 638349 dnaG 4060377 dnaG Lawsonia intracellularis PHE/MN1-00 DNA primase YP_594894.1 636619 R 363253 CDS YP_594895.1 94986962 4060098 complement(638759..639226) 1 NC_008011.1 hypothetical protein 639226 4060098 LI0519 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594895.1 638759 R 363253 CDS YP_594896.1 94986963 4060099 639808..640170 1 NC_008011.1 hypothetical protein 640170 4060099 LI0520 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594896.1 639808 D 363253 CDS YP_594897.1 94986964 4059679 complement(640294..641109) 1 NC_008011.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 641109 ksgA 4059679 ksgA Lawsonia intracellularis PHE/MN1-00 dimethyladenosine transferase YP_594897.1 640294 R 363253 CDS YP_594898.1 94986965 4060100 641246..642406 1 NC_008011.1 glycosyltransferase 642406 4060100 LI0522 Lawsonia intracellularis PHE/MN1-00 glycosyltransferase YP_594898.1 641246 D 363253 CDS YP_594899.1 94986966 4060101 complement(642466..642885) 1 NC_008011.1 hypothetical protein 642885 4060101 LI0523 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594899.1 642466 R 363253 CDS YP_594900.1 94986967 4060102 complement(642894..643238) 1 NC_008011.1 hypothetical protein 643238 4060102 LI0524 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594900.1 642894 R 363253 CDS YP_594901.1 94986968 4060103 complement(643246..643974) 1 NC_008011.1 flagellar basal body-associated protein 643974 4060103 LI0525 Lawsonia intracellularis PHE/MN1-00 flagellar basal body-associated protein YP_594901.1 643246 R 363253 CDS YP_594902.1 94986969 4060422 complement(644060..644440) 1 NC_008011.1 CheY-like receiver 644440 cheY 4060422 cheY Lawsonia intracellularis PHE/MN1-00 CheY-like receiver YP_594902.1 644060 R 363253 CDS YP_594903.1 94986970 4059314 complement(645210..646025) 1 NC_008011.1 chromosome partitioning ATPase 646025 fleN 4059314 fleN Lawsonia intracellularis PHE/MN1-00 chromosome partitioning ATPase YP_594903.1 645210 R 363253 CDS YP_594904.1 94986971 4059733 complement(646068..647129) 1 NC_008011.1 flagellar GTP-binding protein 647129 flhF 4059733 flhF Lawsonia intracellularis PHE/MN1-00 flagellar GTP-binding protein YP_594904.1 646068 R 363253 CDS YP_594905.1 94986972 4060104 complement(647129..649219) 1 NC_008011.1 membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA 649219 flhA 4060104 flhA Lawsonia intracellularis PHE/MN1-00 flagellar biosynthesis protein FlhA YP_594905.1 647129 R 363253 CDS YP_594906.1 94986973 4059732 complement(649308..650381) 1 NC_008011.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB 650381 flhB 4059732 flhB Lawsonia intracellularis PHE/MN1-00 flagellar biosynthesis protein FlhB YP_594906.1 649308 R 363253 CDS YP_594907.1 94986974 4059746 complement(650434..651222) 1 NC_008011.1 flagellar biosynthesis pathway, component FliR 651222 fliR 4059746 fliR Lawsonia intracellularis PHE/MN1-00 flagellar biosynthesis pathway, component FliR YP_594907.1 650434 R 363253 CDS YP_594908.1 94986975 4060105 651739..652329 1 NC_008011.1 transcription elongation factor 652329 4060105 LI0533 Lawsonia intracellularis PHE/MN1-00 transcription elongation factor YP_594908.1 651739 D 363253 CDS YP_594909.1 94986976 4060068 652326..653648 1 NC_008011.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 653648 nusA 4060068 nusA Lawsonia intracellularis PHE/MN1-00 transcription elongation factor NusA YP_594909.1 652326 D 363253 CDS YP_594910.1 94986977 4059669 653879..656764 1 NC_008011.1 translation initiation factor 2 (IF-2; GTPase) 656764 infB 4059669 infB Lawsonia intracellularis PHE/MN1-00 translation initiation factor 2 (IF-2; GTPase) YP_594910.1 653879 D 363253 CDS YP_594911.1 94986978 4060116 657048..658046 1 NC_008011.1 exopolyphosphatase-like protein 658046 mgpa 4060116 mgpa Lawsonia intracellularis PHE/MN1-00 exopolyphosphatase-like protein YP_594911.1 657048 D 363253 CDS YP_594912.1 94986979 4059634 complement(658119..658769) 1 NC_008011.1 part of a set of proteins involved in the infection of eukaryotic cells; in plant pathogens involved in the hypersensitivity response; type III secretion system protein 658769 SctR 4059634 SctR Lawsonia intracellularis PHE/MN1-00 type III secretion system protein YP_594912.1 658119 R 363253 CDS YP_594913.1 94986980 4060106 complement(658794..659876) 1 NC_008011.1 translocation protein in type III secretion 659876 4060106 LI0538 Lawsonia intracellularis PHE/MN1-00 translocation protein in type III secretion YP_594913.1 658794 R 363253 CDS YP_594914.1 94986981 4060107 complement(659919..660416) 1 NC_008011.1 hypothetical protein 660416 4060107 LI0539 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594914.1 659919 R 363253 CDS YP_594915.1 94986982 4059633 complement(660438..661754) 1 NC_008011.1 type III secretion system ATPase 661754 sctN 4059633 sctN Lawsonia intracellularis PHE/MN1-00 type III secretion system ATPase YP_594915.1 660438 R 363253 CDS YP_594916.1 94986983 4059632 complement(661775..662389) 1 NC_008011.1 type III secretion system protein 662389 sctL 4059632 sctL Lawsonia intracellularis PHE/MN1-00 type III secretion system protein YP_594916.1 661775 R 363253 CDS YP_594917.1 94986984 4060108 complement(662368..663072) 1 NC_008011.1 hypothetical protein 663072 4060108 LI0542 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594917.1 662368 R 363253 CDS YP_594918.1 94986985 4060061 complement(663072..663944) 1 NC_008011.1 LscJ 663944 nolT 4060061 nolT Lawsonia intracellularis PHE/MN1-00 LscJ YP_594918.1 663072 R 363253 CDS YP_594919.1 94986986 4060109 complement(663958..664335) 1 NC_008011.1 hypothetical protein 664335 4060109 LI0544 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594919.1 663958 R 363253 CDS YP_594920.1 94986987 4060110 complement(665261..665557) 1 NC_008011.1 hypothetical protein 665557 4060110 LI0545 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594920.1 665261 R 363253 CDS YP_594921.1 94986988 4060111 665820..666182 1 NC_008011.1 hypothetical protein 666182 4060111 LI0546 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594921.1 665820 D 363253 CDS YP_594922.1 94986989 4059565 666388..666729 1 NC_008011.1 hypothetical protein 666729 4059565 LI0547 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594922.1 666388 D 363253 CDS YP_594923.1 94986990 4059543 666726..668828 1 NC_008011.1 type III secretion pore protein 668828 yscV 4059543 yscV Lawsonia intracellularis PHE/MN1-00 type III secretion pore protein YP_594923.1 666726 D 363253 CDS YP_594924.1 94986991 4059540 668846..669106 1 NC_008011.1 translocation protein in type III secretion 669106 yscS 4059540 yscS Lawsonia intracellularis PHE/MN1-00 translocation protein in type III secretion YP_594924.1 668846 D 363253 CDS YP_594925.1 94986992 4059541 669154..669969 1 NC_008011.1 Type III secretion component protein SctT 669969 yscT 4059541 yscT Lawsonia intracellularis PHE/MN1-00 Type III secretion component protein SctT YP_594925.1 669154 D 363253 CDS YP_594926.1 94986993 4059542 669966..671048 1 NC_008011.1 translocation protein in type III secretion 671048 yscU 4059542 yscU Lawsonia intracellularis PHE/MN1-00 translocation protein in type III secretion YP_594926.1 669966 D 363253 CDS YP_594927.1 94986994 4059566 677116..681264 1 NC_008011.1 Signal transduction histidine kinase 681264 4059566 LI0552 Lawsonia intracellularis PHE/MN1-00 Signal transduction histidine kinase YP_594927.1 677116 D 363253 CDS YP_594928.1 94986995 4060138 681626..682891 1 NC_008011.1 diaminopimelate decarboxylase 682891 lysA 4060138 lysA Lawsonia intracellularis PHE/MN1-00 diaminopimelate decarboxylase YP_594928.1 681626 D 363253 CDS YP_594929.1 94986996 4059567 682917..684095 1 NC_008011.1 hypothetical protein 684095 4059567 LI0554 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594929.1 682917 D 363253 CDS YP_594930.1 94986997 4059568 684290..685045 1 NC_008011.1 hypothetical protein 685045 4059568 LI0555 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594930.1 684290 D 363253 CDS YP_594931.1 94986998 4059569 685227..686414 1 NC_008011.1 major facilitator superfamily permease 686414 4059569 LI0556 Lawsonia intracellularis PHE/MN1-00 major facilitator superfamily permease YP_594931.1 685227 D 363253 CDS YP_594932.1 94986999 4060393 686543..687343 1 NC_008011.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters UDP disphosphate which reduces the pool of lipid carrier available to the cell; UDP pyrophosphate phosphatase 687343 bacA 4060393 bacA Lawsonia intracellularis PHE/MN1-00 UDP pyrophosphate phosphatase YP_594932.1 686543 D 363253 CDS YP_594933.1 94987000 4059570 complement(687407..688678) 1 NC_008011.1 competence protein ComGF 688678 4059570 LI0558 Lawsonia intracellularis PHE/MN1-00 competence protein ComGF YP_594933.1 687407 R 363253 CDS YP_594934.1 94987001 4059885 688844..689278 1 NC_008011.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 689278 rplM 4059885 rplM Lawsonia intracellularis PHE/MN1-00 50S ribosomal protein L13 YP_594934.1 688844 D 363253 CDS YP_594935.1 94987002 4059571 689297..689689 1 NC_008011.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 689689 rpsI 4059571 rpsI Lawsonia intracellularis PHE/MN1-00 30S ribosomal protein S9 YP_594935.1 689297 D 363253 CDS YP_594936.1 94987003 4059572 689868..691523 1 NC_008011.1 metallo-beta-lactamase superfamily hydrolase 691523 4059572 LI0561 Lawsonia intracellularis PHE/MN1-00 metallo-beta-lactamase superfamily hydrolase YP_594936.1 689868 D 363253 CDS YP_594937.1 94987004 4059573 691765..692793 1 NC_008011.1 hypothetical protein 692793 4059573 LI0562 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594937.1 691765 D 363253 CDS YP_594938.1 94987005 4059574 complement(693085..693444) 1 NC_008011.1 hypothetical protein 693444 4059574 LI0563 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594938.1 693085 R 363253 CDS YP_594939.1 94987006 4059995 693561..694052 1 NC_008011.1 phosphatidylglycerophosphatase A and related proteins 694052 pgpA 4059995 pgpA Lawsonia intracellularis PHE/MN1-00 phosphatidylglycerophosphatase A and related proteins YP_594939.1 693561 D 363253 CDS YP_594940.1 94987007 4059575 694166..694642 1 NC_008011.1 hypothetical protein 694642 4059575 LI0565 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594940.1 694166 D 363253 CDS YP_594941.1 94987008 4059723 complement(694775..696847) 1 NC_008011.1 flagellar hook protein FlgE 696847 flgE 4059723 flgE Lawsonia intracellularis PHE/MN1-00 flagellar hook protein FlgE YP_594941.1 694775 R 363253 CDS YP_594942.1 94987009 4059576 complement(696931..697770) 1 NC_008011.1 flagellar hook capping protein 697770 4059576 LI0567 Lawsonia intracellularis PHE/MN1-00 flagellar hook capping protein YP_594942.1 696931 R 363253 CDS YP_594943.1 94987010 4059577 complement(697783..699609) 1 NC_008011.1 flagellar hook-length control protein 699609 4059577 LI0568 Lawsonia intracellularis PHE/MN1-00 flagellar hook-length control protein YP_594943.1 697783 R 363253 CDS YP_594944.1 94987011 4059578 complement(699820..701229) 1 NC_008011.1 ADP-heptose:LPS heptosyltransferase 701229 4059578 LI0569 Lawsonia intracellularis PHE/MN1-00 ADP-heptose:LPS heptosyltransferase YP_594944.1 699820 R 363253 CDS YP_594945.1 94987012 4059735 701958..702842 1 NC_008011.1 flagellin-like protein 702842 fliC 4059735 fliC Lawsonia intracellularis PHE/MN1-00 flagellin-like protein YP_594945.1 701958 D 363253 CDS YP_594946.1 94987013 4059906 complement(703046..703747) 1 NC_008011.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 703747 rnc 4059906 rnc Lawsonia intracellularis PHE/MN1-00 ribonuclease III YP_594946.1 703046 R 363253 CDS YP_594947.1 94987014 4059579 703881..704216 1 NC_008011.1 hypothetical protein 704216 4059579 LI0572 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594947.1 703881 D 363253 CDS YP_594948.1 94987015 4059580 complement(704639..705160) 1 NC_008011.1 RimM protein, required for 16S rRNA processing 705160 4059580 LI0573 Lawsonia intracellularis PHE/MN1-00 RimM protein, required for 16S rRNA processing YP_594948.1 704639 R 363253 CDS YP_594949.1 94987016 4059581 complement(705170..705403) 1 NC_008011.1 RNA-binding protein 705403 4059581 LI0574 Lawsonia intracellularis PHE/MN1-00 RNA-binding protein YP_594949.1 705170 R 363253 CDS YP_594950.1 94987017 4059582 complement(705860..707374) 1 NC_008011.1 Signal renition particle GTPase 707374 4059582 LI0575 Lawsonia intracellularis PHE/MN1-00 Signal renition particle GTPase YP_594950.1 705860 R 363253 CDS YP_594951.1 94987018 4059835 complement(707511..708923) 1 NC_008011.1 RNA methyltransferase 708923 trmA 4059835 trmA Lawsonia intracellularis PHE/MN1-00 RNA methyltransferase YP_594951.1 707511 R 363253 CDS YP_594952.1 94987019 4059583 complement(708959..709837) 1 NC_008011.1 dTDP-glucose pyrophosphorylase 709837 4059583 LI0577 Lawsonia intracellularis PHE/MN1-00 dTDP-glucose pyrophosphorylase YP_594952.1 708959 R 363253 CDS YP_594953.1 94987020 4059956 709985..710578 1 NC_008011.1 AICAR transformylase/IMP cyclohydrolase PurH 710578 purH 4059956 purH Lawsonia intracellularis PHE/MN1-00 AICAR transformylase/IMP cyclohydrolase PurH YP_594953.1 709985 D 363253 CDS YP_594954.1 94987021 4060084 710794..711201 1 NC_008011.1 NTP pyrophosphohydrolases including oxidative damage repair enzymes 711201 mutT 4060084 mutT Lawsonia intracellularis PHE/MN1-00 NTP pyrophosphohydrolases including oxidative damage repair enzymes YP_594954.1 710794 D 363253 CDS YP_594955.1 94987022 4059584 complement(711302..712312) 1 NC_008011.1 nucleoside-diphosphate-sugar epimerases 712312 4059584 LI0580 Lawsonia intracellularis PHE/MN1-00 nucleoside-diphosphate-sugar epimerases YP_594955.1 711302 R 363253 CDS YP_594956.1 94987023 4059585 complement(712325..713056) 1 NC_008011.1 hypothetical protein 713056 4059585 LI0581 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594956.1 712325 R 363253 CDS YP_594957.1 94987024 4059586 complement(713038..714246) 1 NC_008011.1 phosphopantothenoylcysteine synthetase/decarboxylase 714246 4059586 LI0582 Lawsonia intracellularis PHE/MN1-00 phosphopantothenoylcysteine synthetase/decarboxylase YP_594957.1 713038 R 363253 CDS YP_594958.1 94987025 4059587 complement(714243..714791) 1 NC_008011.1 hypothetical protein 714791 4059587 LI0583 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594958.1 714243 R 363253 CDS YP_594959.1 94987026 4059588 715334..715945 1 NC_008011.1 hypothetical protein 715945 4059588 LI0584 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594959.1 715334 D 363253 CDS YP_594960.1 94987027 4059589 716001..717314 1 NC_008011.1 DNA repair exonuclease 717314 4059589 LI0585 Lawsonia intracellularis PHE/MN1-00 DNA repair exonuclease YP_594960.1 716001 D 363253 CDS YP_594961.1 94987028 4059590 717314..721276 1 NC_008011.1 hypothetical protein 721276 4059590 LI0586 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594961.1 717314 D 363253 CDS YP_594962.1 94987029 4059591 complement(721314..721958) 1 NC_008011.1 hypothetical protein 721958 4059591 LI0587 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594962.1 721314 R 363253 CDS YP_594963.1 94987030 4059810 complement(722079..723026) 1 NC_008011.1 Sec-independent protein secretion pathway component TatC 723026 tatC 4059810 tatC Lawsonia intracellularis PHE/MN1-00 Sec-independent protein secretion pathway component TatC YP_594963.1 722079 R 363253 CDS YP_594964.1 94987031 4059592 complement(723056..723421) 1 NC_008011.1 Sec-independent protein secretion pathway components 723421 4059592 LI0589 Lawsonia intracellularis PHE/MN1-00 Sec-independent protein secretion pathway components YP_594964.1 723056 R 363253 CDS YP_594965.1 94987032 4060256 complement(723704..725245) 1 NC_008011.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 725245 guaA 4060256 guaA Lawsonia intracellularis PHE/MN1-00 GMP synthase YP_594965.1 723704 R 363253 CDS YP_594966.1 94987033 4060257 complement(725358..726833) 1 NC_008011.1 IMP dehydrogenase/GMP reductase 726833 guaB 4060257 guaB Lawsonia intracellularis PHE/MN1-00 IMP dehydrogenase/GMP reductase YP_594966.1 725358 R 363253 CDS YP_594967.1 94987034 4060143 727151..727738 1 NC_008011.1 maltose transacetylase 727738 maa 4060143 maa Lawsonia intracellularis PHE/MN1-00 maltose transacetylase YP_594967.1 727151 D 363253 CDS YP_594968.1 94987035 4060429 727939..729378 1 NC_008011.1 phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase-like protein 729378 cls 4060429 cls Lawsonia intracellularis PHE/MN1-00 phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase-like protein YP_594968.1 727939 D 363253 CDS YP_594969.1 94987036 4059905 complement(729401..731842) 1 NC_008011.1 exoribonuclease R 731842 rnb 4059905 rnb Lawsonia intracellularis PHE/MN1-00 exoribonuclease R YP_594969.1 729401 R 363253 CDS YP_594970.1 94987037 4060136 complement(731866..733320) 1 NC_008011.1 tetraacyldisaccharide-1-P 4'-kinase 733320 lpxK 4060136 lpxK Lawsonia intracellularis PHE/MN1-00 tetraacyldisaccharide-1-P 4'-kinase YP_594970.1 731866 R 363253 CDS YP_594971.1 94987038 4059832 complement(733491..734009) 1 NC_008011.1 peroxiredoxin 734009 tpx 4059832 tpx Lawsonia intracellularis PHE/MN1-00 peroxiredoxin YP_594971.1 733491 R 363253 CDS YP_594972.1 94987039 4059593 734850..737261 1 NC_008011.1 TPR repeat-containing protein 737261 4059593 LI0597 Lawsonia intracellularis PHE/MN1-00 TPR repeat-containing protein YP_594972.1 734850 D 363253 CDS YP_594973.1 94987040 4059544 complement(737302..739368) 1 NC_008011.1 cation-transporting ATPase, P-type 739368 zntA 4059544 zntA Lawsonia intracellularis PHE/MN1-00 cation-transporting ATPase, P-type YP_594973.1 737302 R 363253 CDS YP_594974.1 94987041 4060022 complement(739657..741138) 1 NC_008011.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter 741138 panF 4060022 panF Lawsonia intracellularis PHE/MN1-00 sodium/panthothenate symporter YP_594974.1 739657 R 363253 CDS YP_594975.1 94987042 4059594 complement(741141..741506) 1 NC_008011.1 hypothetical protein 741506 4059594 LI0600 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594975.1 741141 R 363253 CDS YP_594976.1 94987043 4059595 742192..743511 1 NC_008011.1 voltage-gated chloride channel family protein 743511 4059595 LI0601 Lawsonia intracellularis PHE/MN1-00 voltage-gated chloride channel family protein YP_594976.1 742192 D 363253 CDS YP_594977.1 94987044 4059596 743611..744357 1 NC_008011.1 metal dependent hydrolases 744357 4059596 LI0602 Lawsonia intracellularis PHE/MN1-00 metal dependent hydrolases YP_594977.1 743611 D 363253 CDS YP_594978.1 94987045 4059597 744711..746285 1 NC_008011.1 two-component response regulator 746285 4059597 LI0603 Lawsonia intracellularis PHE/MN1-00 two-component response regulator YP_594978.1 744711 D 363253 CDS YP_594979.1 94987046 4059598 746343..747425 1 NC_008011.1 PleD 747425 4059598 LI0604 Lawsonia intracellularis PHE/MN1-00 PleD YP_594979.1 746343 D 363253 CDS YP_594980.1 94987047 4059599 complement(747467..748333) 1 NC_008011.1 hypothetical protein 748333 4059599 LI0605 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594980.1 747467 R 363253 CDS YP_594981.1 94987048 4059600 complement(748457..749158) 1 NC_008011.1 transcriptional regulator 749158 4059600 LI0606 Lawsonia intracellularis PHE/MN1-00 transcriptional regulator YP_594981.1 748457 R 363253 CDS YP_594982.1 94987049 4059601 complement(749754..751250) 1 NC_008011.1 TPR repeat-containing Zn-dependent protease 751250 4059601 LI0607 Lawsonia intracellularis PHE/MN1-00 TPR repeat-containing Zn-dependent protease YP_594982.1 749754 R 363253 CDS YP_594983.1 94987050 4060443 complement(751382..752839) 1 NC_008011.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 752839 cysS 4060443 cysS Lawsonia intracellularis PHE/MN1-00 cysteinyl-tRNA synthetase YP_594983.1 751382 R 363253 CDS YP_594984.1 94987051 4059913 complement(752940..753368) 1 NC_008011.1 ribose 5-phosphate isomerase RpiB 753368 rpiB 4059913 rpiB Lawsonia intracellularis PHE/MN1-00 ribose 5-phosphate isomerase RpiB YP_594984.1 752940 R 363253 CDS YP_594985.1 94987052 4059602 complement(753377..753721) 1 NC_008011.1 hypothetical protein 753721 4059602 LI0610 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594985.1 753377 R 363253 CDS YP_594986.1 94987053 4059603 complement(753798..754583) 1 NC_008011.1 hypothetical protein 754583 4059603 LI0611 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594986.1 753798 R 363253 CDS YP_594987.1 94987054 4059702 complement(754591..756312) 1 NC_008011.1 TPR repeat-containing protein 756312 4059702 LI0612 Lawsonia intracellularis PHE/MN1-00 TPR repeat-containing protein YP_594987.1 754591 R 363253 CDS YP_594988.1 94987055 4059800 complement(756332..757489) 1 NC_008011.1 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) 757489 sigB 4059800 sigB Lawsonia intracellularis PHE/MN1-00 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) YP_594988.1 756332 R 363253 CDS YP_594989.1 94987056 4059703 758603..759070 1 NC_008011.1 Thiol-disulfide isomerase and thioredoxins 759070 4059703 LI0614 Lawsonia intracellularis PHE/MN1-00 Thiol-disulfide isomerase and thioredoxins YP_594989.1 758603 D 363253 CDS YP_594990.1 94987057 4059704 759733..760479 1 NC_008011.1 hypothetical protein 760479 4059704 LI0615 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594990.1 759733 D 363253 CDS YP_594991.1 94987058 4059936 760506..761837 1 NC_008011.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 761837 radA 4059936 radA Lawsonia intracellularis PHE/MN1-00 DNA repair protein RadA YP_594991.1 760506 D 363253 CDS YP_594992.1 94987059 4059535 761962..762291 1 NC_008011.1 hypothetical protein 762291 yljA 4059535 yljA Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_594992.1 761962 D 363253 CDS YP_594993.1 94987060 4059705 762288..764534 1 NC_008011.1 ATPases with chaperone activity, ATP-binding subunit 764534 4059705 LI0618 Lawsonia intracellularis PHE/MN1-00 ATPases with chaperone activity, ATP-binding subunit YP_594993.1 762288 D 363253 CDS YP_594994.1 94987061 4060337 764629..765315 1 NC_008011.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase 765315 aat 4060337 aat Lawsonia intracellularis PHE/MN1-00 leucyl/phenylalanyl-tRNA--protein transferase YP_594994.1 764629 D 363253 CDS YP_594995.1 94987062 4060428 complement(765529..766827) 1 NC_008011.1 deacetylase 766827 clr3 4060428 clr3 Lawsonia intracellularis PHE/MN1-00 deacetylase YP_594995.1 765529 R 363253 CDS YP_594996.1 94987063 4059706 complement(767002..767973) 1 NC_008011.1 nucleoside-diphosphate-sugar epimerases 767973 4059706 LI0621 Lawsonia intracellularis PHE/MN1-00 nucleoside-diphosphate-sugar epimerases YP_594996.1 767002 R 363253 CDS YP_594997.1 94987064 4059707 complement(768129..769223) 1 NC_008011.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 769223 obgE 4059707 obgE Lawsonia intracellularis PHE/MN1-00 GTPase ObgE YP_594997.1 768129 R 363253 CDS YP_594998.1 94987065 4059894 complement(769665..769973) 1 NC_008011.1 50S ribosomal protein L21 769973 rplU 4059894 rplU Lawsonia intracellularis PHE/MN1-00 50S ribosomal protein L21 YP_594998.1 769665 R 363253 CDS YP_594999.1 94987066 4059708 770472..770777 1 NC_008011.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 770777 groES 4059708 groES Lawsonia intracellularis PHE/MN1-00 co-chaperonin GroES YP_594999.1 770472 D 363253 CDS YP_595000.1 94987067 4059709 770925..772571 1 NC_008011.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 772571 groEL 4059709 groEL Lawsonia intracellularis PHE/MN1-00 chaperonin GroEL YP_595000.1 770925 D 363253 CDS YP_595001.1 94987068 4059710 772698..773579 1 NC_008011.1 protoporphyrinogen oxidase 773579 4059710 LI0626 Lawsonia intracellularis PHE/MN1-00 protoporphyrinogen oxidase YP_595001.1 772698 D 363253 CDS YP_595002.1 94987069 4060134 773705..774619 1 NC_008011.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 774619 lpxC 4060134 lpxC Lawsonia intracellularis PHE/MN1-00 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase YP_595002.1 773705 D 363253 CDS YP_595003.1 94987070 4060081 774694..776640 1 NC_008011.1 DNA mismatch repair ATPase 776640 mutL 4060081 mutL Lawsonia intracellularis PHE/MN1-00 DNA mismatch repair ATPase YP_595003.1 774694 D 363253 CDS YP_595004.1 94987071 4059711 complement(776669..778213) 1 NC_008011.1 hypothetical protein 778213 4059711 LI0629 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595004.1 776669 R 363253 CDS YP_595005.1 94987072 4059635 complement(778307..780802) 1 NC_008011.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 780802 secA 4059635 secA Lawsonia intracellularis PHE/MN1-00 preprotein translocase subunit SecA YP_595005.1 778307 R 363253 CDS YP_595006.1 94987073 4059664 complement(780948..781964) 1 NC_008011.1 hydrogenase maturation factor 781964 hypE 4059664 hypE Lawsonia intracellularis PHE/MN1-00 hydrogenase maturation factor YP_595006.1 780948 R 363253 CDS YP_595007.1 94987074 4059712 complement(782118..783515) 1 NC_008011.1 major facilitator superfamily permease 783515 4059712 LI0632 Lawsonia intracellularis PHE/MN1-00 major facilitator superfamily permease YP_595007.1 782118 R 363253 CDS YP_595008.1 94987075 4059731 complement(783773..784090) 1 NC_008011.1 hypothetical protein 784090 flgM 4059731 flgM Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595008.1 783773 R 363253 CDS YP_595009.1 94987076 4059713 complement(784118..784528) 1 NC_008011.1 hypothetical protein 784528 4059713 LI0634 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595009.1 784118 R 363253 CDS YP_595010.1 94987077 4060019 784911..786176 1 NC_008011.1 coenzyme F390 synthetase 786176 paaK 4060019 paaK Lawsonia intracellularis PHE/MN1-00 coenzyme F390 synthetase YP_595010.1 784911 D 363253 CDS YP_595011.1 94987078 4059714 complement(787082..787888) 1 NC_008011.1 hypothetical protein 787888 4059714 LI0636 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595011.1 787082 R 363253 CDS YP_595012.1 94987079 4060082 complement(787956..788795) 1 NC_008011.1 formamidopyrimidine-DNA glycosylase 788795 mutM 4060082 mutM Lawsonia intracellularis PHE/MN1-00 formamidopyrimidine-DNA glycosylase YP_595012.1 787956 R 363253 CDS YP_595013.1 94987080 4059715 complement(788870..789181) 1 NC_008011.1 hypothetical protein 789181 4059715 LI0638 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595013.1 788870 R 363253 CDS YP_595014.1 94987081 4059745 complement(789827..790615) 1 NC_008011.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 790615 fliP 4059745 fliP Lawsonia intracellularis PHE/MN1-00 flagellar biosynthesis protein FliP YP_595014.1 789827 R 363253 CDS YP_595015.1 94987082 4059716 complement(790596..791090) 1 NC_008011.1 flagellar biogenesis protein 791090 4059716 LI0640 Lawsonia intracellularis PHE/MN1-00 flagellar biogenesis protein YP_595015.1 790596 R 363253 CDS YP_595016.1 94987083 4059744 complement(791116..791610) 1 NC_008011.1 flagellar motor switch/type III secretory pathway protein 791610 fliN 4059744 fliN Lawsonia intracellularis PHE/MN1-00 flagellar motor switch/type III secretory pathway protein YP_595016.1 791116 R 363253 CDS YP_595017.1 94987084 4059742 complement(791623..792192) 1 NC_008011.1 flagellar basal body-associated protein 792192 fliL 4059742 fliL Lawsonia intracellularis PHE/MN1-00 flagellar basal body-associated protein YP_595017.1 791623 R 363253 CDS YP_595018.1 94987085 4059717 complement(792334..793035) 1 NC_008011.1 TIM-barrel fold family protein 793035 4059717 LI0643 Lawsonia intracellularis PHE/MN1-00 TIM-barrel fold family protein YP_595018.1 792334 R 363253 CDS YP_595019.1 94987086 4059718 complement(793032..794006) 1 NC_008011.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 794006 era 4059718 era Lawsonia intracellularis PHE/MN1-00 GTP-binding protein Era YP_595019.1 793032 R 363253 CDS YP_595020.1 94987087 4059691 complement(794233..795093) 1 NC_008011.1 Zn-dependent protease with chaperone function 795093 htpX 4059691 htpX Lawsonia intracellularis PHE/MN1-00 Zn-dependent protease with chaperone function YP_595020.1 794233 R 363253 CDS YP_595021.1 94987088 4059719 795375..797069 1 NC_008011.1 N-methylhydantoinase A/acetone carboxylase, beta subunit 797069 4059719 LI0646 Lawsonia intracellularis PHE/MN1-00 N-methylhydantoinase A/acetone carboxylase, beta subunit YP_595021.1 795375 D 363253 CDS YP_595022.1 94987089 4059720 complement(797066..798295) 1 NC_008011.1 hypothetical protein 798295 4059720 LI0647 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595022.1 797066 R 363253 CDS YP_595023.1 94987090 4059610 799057..801705 1 NC_008011.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 801705 valS 4059610 valS Lawsonia intracellularis PHE/MN1-00 valyl-tRNA synthetase YP_595023.1 799057 D 363253 CDS YP_595024.1 94987091 4059545 802639..805194 1 NC_008011.1 hypothetical protein 805194 4059545 LI0649 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595024.1 802639 D 363253 CDS YP_595025.1 94987092 4059546 806068..808959 1 NC_008011.1 Zn-dependent peptidases, insulinase-like 808959 4059546 LI0650 Lawsonia intracellularis PHE/MN1-00 Zn-dependent peptidases, insulinase-like YP_595025.1 806068 D 363253 CDS YP_595026.1 94987093 4060091 809068..810786 1 NC_008011.1 rhodanese-related sulfurtransferase 810786 nadh 4060091 nadh Lawsonia intracellularis PHE/MN1-00 rhodanese-related sulfurtransferase YP_595026.1 809068 D 363253 CDS YP_595027.1 94987094 4059547 complement(810827..811642) 1 NC_008011.1 DNA adenine methylase 811642 4059547 LI0652 Lawsonia intracellularis PHE/MN1-00 DNA adenine methylase YP_595027.1 810827 R 363253 CDS YP_595028.1 94987095 4059548 complement(811686..812498) 1 NC_008011.1 Zn-dependent protease with chaperone function 812498 4059548 LI0653 Lawsonia intracellularis PHE/MN1-00 Zn-dependent protease with chaperone function YP_595028.1 811686 R 363253 CDS YP_595029.1 94987096 4059830 812614..814878 1 NC_008011.1 zinc finger domain-containing protein 814878 topA 4059830 topA Lawsonia intracellularis PHE/MN1-00 zinc finger domain-containing protein YP_595029.1 812614 D 363253 CDS YP_595030.1 94987097 4060218 814978..815604 1 NC_008011.1 Zn-dependent hydrolases, including glyoxylases 815604 gloB 4060218 gloB Lawsonia intracellularis PHE/MN1-00 Zn-dependent hydrolases, including glyoxylases YP_595030.1 814978 D 363253 CDS YP_595031.1 94987098 4059380 815668..816861 1 NC_008011.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase 816861 argG 4059380 argG Lawsonia intracellularis PHE/MN1-00 argininosuccinate synthase YP_595031.1 815668 D 363253 CDS YP_595032.1 94987099 4059381 816949..818331 1 NC_008011.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 818331 argH 4059381 argH Lawsonia intracellularis PHE/MN1-00 argininosuccinate lyase YP_595032.1 816949 D 363253 CDS YP_595033.1 94987100 4059493 818505..819497 1 NC_008011.1 tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase 819497 trmU 4059493 trmU Lawsonia intracellularis PHE/MN1-00 tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase YP_595033.1 818505 D 363253 CDS YP_595034.1 94987101 4059549 819913..820452 1 NC_008011.1 shikimate kinase 820452 4059549 LI0659 Lawsonia intracellularis PHE/MN1-00 shikimate kinase YP_595034.1 819913 D 363253 CDS YP_595035.1 94987102 4060394 complement(820449..820991) 1 NC_008011.1 bacterioferritin (cytochrome b1) 820991 bfr 4060394 bfr Lawsonia intracellularis PHE/MN1-00 bacterioferritin (cytochrome b1) YP_595035.1 820449 R 363253 CDS YP_595036.1 94987103 4060327 821433..823262 1 NC_008011.1 glucosamine 6-phosphate synthetase 823262 glmS 4060327 glmS Lawsonia intracellularis PHE/MN1-00 glucosamine 6-phosphate synthetase YP_595036.1 821433 D 363253 CDS YP_595037.1 94987104 4059550 823446..826448 1 NC_008011.1 hypothetical protein 826448 4059550 LI0662 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595037.1 823446 D 363253 CDS YP_595038.1 94987105 4059551 828562..828969 1 NC_008011.1 hypothetical protein 828969 4059551 LI0663 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595038.1 828562 D 363253 CDS YP_595039.1 94987106 4059552 829283..830440 1 NC_008011.1 hypothetical protein 830440 4059552 LI0664 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595039.1 829283 D 363253 CDS YP_595040.1 94987107 4059553 complement(830885..831484) 1 NC_008011.1 hypothetical protein 831484 4059553 LI0665 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595040.1 830885 R 363253 CDS YP_595041.1 94987108 4059554 complement(831665..832279) 1 NC_008011.1 hypothetical protein 832279 4059554 LI0666 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595041.1 831665 R 363253 CDS YP_595042.1 94987109 4059555 complement(833929..835044) 1 NC_008011.1 hypothetical protein 835044 4059555 LI0667 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595042.1 833929 R 363253 CDS YP_595043.1 94987110 4059556 complement(835309..836481) 1 NC_008011.1 hypothetical protein 836481 4059556 LI0668 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595043.1 835309 R 363253 CDS YP_595044.1 94987111 4059557 complement(<836694..837119) 1 NC_008011.1 hypothetical protein 837119 4059557 LI0669 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595044.1 <836694 R 363253 CDS YP_595045.1 94987112 4060343 839619..841052 1 NC_008011.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine; S-adenosyl-L-homocysteine hydrolase 841052 ahcY 4060343 ahcY Lawsonia intracellularis PHE/MN1-00 S-adenosyl-L-homocysteine hydrolase YP_595045.1 839619 D 363253 CDS YP_595046.1 94987113 4059642 841336..842244 1 NC_008011.1 phosphoglycerate dehydrogenase and related dehydrogenases 842244 serA 4059642 serA Lawsonia intracellularis PHE/MN1-00 phosphoglycerate dehydrogenase and related dehydrogenases YP_595046.1 841336 D 363253 CDS YP_595047.1 94987114 4060025 842275..844410 1 NC_008011.1 superfamily I DNA/RNA helicase 844410 pcrA 4060025 pcrA Lawsonia intracellularis PHE/MN1-00 superfamily I DNA/RNA helicase YP_595047.1 842275 D 363253 CDS YP_595048.1 94987115 4059822 844426..845448 1 NC_008011.1 thiamine monophosphate kinase 845448 thiL 4059822 thiL Lawsonia intracellularis PHE/MN1-00 thiamine monophosphate kinase YP_595048.1 844426 D 363253 CDS YP_595049.1 94987116 4059558 complement(845474..846838) 1 NC_008011.1 hypothetical protein 846838 4059558 LI0674 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595049.1 845474 R 363253 CDS YP_595050.1 94987117 4060267 847108..848259 1 NC_008011.1 membrane protease subunits, stomatin/prohibitin homologs 848259 hflK 4060267 hflK Lawsonia intracellularis PHE/MN1-00 membrane protease subunits, stomatin/prohibitin homologs YP_595050.1 847108 D 363253 CDS YP_595051.1 94987118 4060266 848260..849111 1 NC_008011.1 membrane protease subunits, stomatin/prohibitin homologs 849111 hflC 4060266 hflC Lawsonia intracellularis PHE/MN1-00 membrane protease subunits, stomatin/prohibitin homologs YP_595051.1 848260 D 363253 CDS YP_595052.1 94987119 4059559 849077..849838 1 NC_008011.1 hypothetical protein 849838 4059559 LI0677 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595052.1 849077 D 363253 CDS YP_595053.1 94987120 4059560 complement(849897..851219) 1 NC_008011.1 2-methylthioadenine synthetase 851219 4059560 LI0678 Lawsonia intracellularis PHE/MN1-00 2-methylthioadenine synthetase YP_595053.1 849897 R 363253 CDS YP_595054.1 94987121 4059561 851253..852002 1 NC_008011.1 xanthosine triphosphate pyrophosphatase 852002 4059561 LI0679 Lawsonia intracellularis PHE/MN1-00 xanthosine triphosphate pyrophosphatase YP_595054.1 851253 D 363253 CDS YP_595055.1 94987122 4059562 852068..853144 1 NC_008011.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 853144 4059562 LI0680 Lawsonia intracellularis PHE/MN1-00 ribosomal RNA large subunit methyltransferase N YP_595055.1 852068 D 363253 CDS YP_595056.1 94987123 4059675 complement(853157..854476) 1 NC_008011.1 3-deoxy-D-manno-octulosonic-acid transferase 854476 kdtA 4059675 kdtA Lawsonia intracellularis PHE/MN1-00 3-deoxy-D-manno-octulosonic-acid transferase YP_595056.1 853157 R 363253 CDS YP_595057.1 94987124 4060371 complement(854481..855389) 1 NC_008011.1 D-alanine-D-alanine ligase and related ATP-grasp enzymes 855389 ddlA 4060371 ddlA Lawsonia intracellularis PHE/MN1-00 D-alanine-D-alanine ligase and related ATP-grasp enzymes YP_595057.1 854481 R 363253 CDS YP_595058.1 94987125 4059563 complement(855346..855987) 1 NC_008011.1 hypothetical protein 855987 4059563 LI0683 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595058.1 855346 R 363253 CDS YP_595059.1 94987126 4059564 complement(856632..857084) 1 NC_008011.1 acetyltransferase 857084 4059564 LI0684 Lawsonia intracellularis PHE/MN1-00 acetyltransferase YP_595059.1 856632 R 363253 CDS YP_595060.1 94987127 4060378 complement(858662..859786) 1 NC_008011.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 859786 dnaJ 4060378 dnaJ Lawsonia intracellularis PHE/MN1-00 chaperone protein DnaJ YP_595060.1 858662 R 363253 CDS YP_595061.1 94987128 4060026 complement(860201..861736) 1 NC_008011.1 leucyl aminopeptidase 861736 pepA 4060026 pepA Lawsonia intracellularis PHE/MN1-00 leucyl aminopeptidase YP_595061.1 860201 R 363253 CDS YP_595062.1 94987129 4059317 complement(861756..863153) 1 NC_008011.1 response regulator 863153 4059317 LI0687 Lawsonia intracellularis PHE/MN1-00 response regulator YP_595062.1 861756 R 363253 CDS YP_595063.1 94987130 4059318 863417..865222 1 NC_008011.1 Outer membrane protein 865222 4059318 LI0688 Lawsonia intracellularis PHE/MN1-00 Outer membrane protein YP_595063.1 863417 D 363253 CDS YP_595064.1 94987131 4060255 865222..869370 1 NC_008011.1 hypothetical protein 869370 grsT 4060255 grsT Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595064.1 865222 D 363253 CDS YP_595065.1 94987132 4059319 complement(869436..869954) 1 NC_008011.1 hypothetical protein 869954 4059319 LI0690 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595065.1 869436 R 363253 CDS YP_595066.1 94987133 4060021 complement(870411..870899) 1 NC_008011.1 Outer membrane protein and related peptidoglycan-associated (lipo)proteins 870899 pal 4060021 pal Lawsonia intracellularis PHE/MN1-00 Outer membrane protein and related peptidoglycan-associated (lipo)proteins YP_595066.1 870411 R 363253 CDS YP_595067.1 94987134 4059828 complement(871045..872403) 1 NC_008011.1 periplasmic component of the Tol biopolymer transport system 872403 tolB 4059828 tolB Lawsonia intracellularis PHE/MN1-00 periplasmic component of the Tol biopolymer transport system YP_595067.1 871045 R 363253 CDS YP_595068.1 94987135 4059320 complement(872867..873820) 1 NC_008011.1 colicin uptake membrane protein 873820 4059320 LI0693 Lawsonia intracellularis PHE/MN1-00 colicin uptake membrane protein YP_595068.1 872867 R 363253 CDS YP_595069.1 94987136 4059301 complement(873921..874355) 1 NC_008011.1 biopolymer transport protein 874355 exbD 4059301 exbD Lawsonia intracellularis PHE/MN1-00 biopolymer transport protein YP_595069.1 873921 R 363253 CDS YP_595070.1 94987137 4059829 complement(874438..875115) 1 NC_008011.1 biopolymer transport proteins 875115 tolQ 4059829 tolQ Lawsonia intracellularis PHE/MN1-00 biopolymer transport proteins YP_595070.1 874438 R 363253 CDS YP_595071.1 94987138 4059628 875739..876314 1 NC_008011.1 rubrerythrin 876314 rubY 4059628 rubY Lawsonia intracellularis PHE/MN1-00 rubrerythrin YP_595071.1 875739 D 363253 CDS YP_595072.1 94987139 4059627 876328..876531 1 NC_008011.1 rubredoxin 2 (Rd-2) 876531 rubA 4059627 rubA Lawsonia intracellularis PHE/MN1-00 rubredoxin 2 (Rd-2) YP_595072.1 876328 D 363253 CDS YP_595073.1 94987140 4059948 876635..877663 1 NC_008011.1 ADP-heptose:LPS heptosyltransferase II 877663 rfaF 4059948 rfaF Lawsonia intracellularis PHE/MN1-00 ADP-heptose:LPS heptosyltransferase II YP_595073.1 876635 D 363253 CDS YP_595074.1 94987141 4059321 877710..878720 1 NC_008011.1 hypothetical protein 878720 4059321 LI0699 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595074.1 877710 D 363253 CDS YP_595075.1 94987142 4059322 complement(878912..879499) 1 NC_008011.1 TPR repeat-containing protein 879499 4059322 LI0700 Lawsonia intracellularis PHE/MN1-00 TPR repeat-containing protein YP_595075.1 878912 R 363253 CDS YP_595076.1 94987143 4059608 complement(879685..881550) 1 NC_008011.1 nuclease subunit of the excinuclease complex 881550 uvrC 4059608 uvrC Lawsonia intracellularis PHE/MN1-00 nuclease subunit of the excinuclease complex YP_595076.1 879685 R 363253 CDS YP_595077.1 94987144 4060144 complement(881559..882254) 1 NC_008011.1 nucleotide-binding protein implicated in inhibition of septum formation 882254 maf 4060144 maf Lawsonia intracellularis PHE/MN1-00 nucleotide-binding protein implicated in inhibition of septum formation YP_595077.1 881559 R 363253 CDS YP_595078.1 94987145 4059323 882513..883592 1 NC_008011.1 exopolyphosphatase-like protein 883592 4059323 LI0703 Lawsonia intracellularis PHE/MN1-00 exopolyphosphatase-like protein YP_595078.1 882513 D 363253 CDS YP_595079.1 94987146 4059385 complement(883675..885042) 1 NC_008011.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 885042 asnC 4059385 asnC Lawsonia intracellularis PHE/MN1-00 asparaginyl-tRNA synthetase YP_595079.1 883675 R 363253 CDS YP_595080.1 94987147 4059324 complement(885106..885795) 1 NC_008011.1 DedA family protein 885795 4059324 LI0705 Lawsonia intracellularis PHE/MN1-00 DedA family protein YP_595080.1 885106 R 363253 CDS YP_595081.1 94987148 4059325 complement(885880..889188) 1 NC_008011.1 hypothetical protein 889188 4059325 LI0706 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595081.1 885880 R 363253 CDS YP_595082.1 94987149 4059665 complement(889587..891977) 1 NC_008011.1 hydrogenase maturation factor 891977 hypF 4059665 hypF Lawsonia intracellularis PHE/MN1-00 hydrogenase maturation factor YP_595082.1 889587 R 363253 CDS YP_595083.1 94987150 4059326 892189..893016 1 NC_008011.1 protein-disulfide isomerase 893016 4059326 LI0708 Lawsonia intracellularis PHE/MN1-00 protein-disulfide isomerase YP_595083.1 892189 D 363253 CDS YP_595084.1 94987151 4059899 893127..894170 1 NC_008011.1 FAD synthase 894170 ribF 4059899 ribF Lawsonia intracellularis PHE/MN1-00 FAD synthase YP_595084.1 893127 D 363253 CDS YP_595085.1 94987152 4059736 894199..895080 1 NC_008011.1 flagellin-like protein 895080 fliC 4059736 fliC Lawsonia intracellularis PHE/MN1-00 flagellin-like protein YP_595085.1 894199 D 363253 CDS YP_595086.1 94987153 4059327 complement(895227..895730) 1 NC_008011.1 colicin V production membrane protein 895730 4059327 LI0711 Lawsonia intracellularis PHE/MN1-00 colicin V production membrane protein YP_595086.1 895227 R 363253 CDS YP_595087.1 94987154 4059966 complement(896405..897349) 1 NC_008011.1 dihydroorotate dehydrogenase 897349 pyrD 4059966 pyrD Lawsonia intracellularis PHE/MN1-00 dihydroorotate dehydrogenase YP_595087.1 896405 R 363253 CDS YP_595088.1 94987155 4059967 complement(897346..898152) 1 NC_008011.1 2-polyprenylphenol 6-hydroxylase 898152 pyrDII 4059967 pyrDII Lawsonia intracellularis PHE/MN1-00 2-polyprenylphenol 6-hydroxylase YP_595088.1 897346 R 363253 CDS YP_595089.1 94987156 4059382 898390..899574 1 NC_008011.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase 899574 argJ 4059382 argJ Lawsonia intracellularis PHE/MN1-00 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase YP_595089.1 898390 D 363253 CDS YP_595090.1 94987157 4059903 899739..900704 1 NC_008011.1 pseudouridylate synthase 900704 rluD 4059903 rluD Lawsonia intracellularis PHE/MN1-00 pseudouridylate synthase YP_595090.1 899739 D 363253 CDS YP_595091.1 94987158 4060329 900834..901616 1 NC_008011.1 amino acid ABC transporter substrate-binding protein 901616 gln 4060329 gln Lawsonia intracellularis PHE/MN1-00 amino acid ABC transporter substrate-binding protein YP_595091.1 900834 D 363253 CDS YP_595092.1 94987159 4060212 901672..902370 1 NC_008011.1 ABC-type amino acid transport system, permease component 902370 glnP 4060212 glnP Lawsonia intracellularis PHE/MN1-00 ABC-type amino acid transport system, permease component YP_595092.1 901672 D 363253 CDS YP_595093.1 94987160 4060215 902381..903256 1 NC_008011.1 ABC-type polar amino acid transport system, ATPase component 903256 glnQ 4060215 glnQ Lawsonia intracellularis PHE/MN1-00 ABC-type polar amino acid transport system, ATPase component YP_595093.1 902381 D 363253 CDS YP_595094.1 94987161 4059328 903258..903944 1 NC_008011.1 ABC-type amino acid transport system, permease component 903944 4059328 LI0719 Lawsonia intracellularis PHE/MN1-00 ABC-type amino acid transport system, permease component YP_595094.1 903258 D 363253 CDS YP_595095.1 94987162 4059681 903994..905814 1 NC_008011.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 905814 lepA 4059681 lepA Lawsonia intracellularis PHE/MN1-00 GTP-binding protein LepA YP_595095.1 903994 D 363253 CDS YP_595096.1 94987163 4059329 complement(905910..906278) 1 NC_008011.1 transporter 906278 4059329 LI0721 Lawsonia intracellularis PHE/MN1-00 transporter YP_595096.1 905910 R 363253 CDS YP_595097.1 94987164 4059330 complement(906849..908045) 1 NC_008011.1 hypothetical protein 908045 4059330 LI0722 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595097.1 906849 R 363253 CDS YP_595098.1 94987165 4060120 complement(908182..909393) 1 NC_008011.1 membrane-bound lytic murein transglycosylase 909393 mltA 4060120 mltA Lawsonia intracellularis PHE/MN1-00 membrane-bound lytic murein transglycosylase YP_595098.1 908182 R 363253 CDS YP_595099.1 94987166 4059331 909409..909858 1 NC_008011.1 thioesterase 909858 4059331 LI0724 Lawsonia intracellularis PHE/MN1-00 thioesterase YP_595099.1 909409 D 363253 CDS YP_595100.1 94987167 4059684 complement(910107..910928) 1 NC_008011.1 PHP family histidinol phosphatase/hydrolase 910928 hisB 4059684 hisB Lawsonia intracellularis PHE/MN1-00 PHP family histidinol phosphatase/hydrolase YP_595100.1 910107 R 363253 CDS YP_595101.2 162138293 4060115 complement(911020..912195) 1 NC_008011.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 912195 metK 4060115 metK Lawsonia intracellularis PHE/MN1-00 S-adenosylmethionine synthetase YP_595101.2 911020 R 363253 CDS YP_595102.1 94987169 4059332 912401..912991 1 NC_008011.1 hypothetical protein 912991 4059332 LI0727 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595102.1 912401 D 363253 CDS YP_595103.1 94987170 4060141 912997..913881 1 NC_008011.1 ribosomal protein S1 913881 lytB 4060141 lytB Lawsonia intracellularis PHE/MN1-00 ribosomal protein S1 YP_595103.1 912997 D 363253 CDS YP_595104.1 94987171 4060418 913946..914896 1 NC_008011.1 chemotaxis signal transduction protein 914896 cheV 4060418 cheV Lawsonia intracellularis PHE/MN1-00 chemotaxis signal transduction protein YP_595104.1 913946 D 363253 CDS YP_595105.1 94987172 4059511 complement(914956..916287) 1 NC_008011.1 UDP-glucose 6-dehydrogenase 916287 ugd 4059511 ugd Lawsonia intracellularis PHE/MN1-00 UDP-glucose 6-dehydrogenase YP_595105.1 914956 R 363253 CDS YP_595106.1 94987173 4060340 916424..916801 1 NC_008011.1 holo-ACP synthase 916801 acpS 4060340 acpS Lawsonia intracellularis PHE/MN1-00 holo-ACP synthase YP_595106.1 916424 D 363253 CDS YP_595107.1 94987174 4059690 916828..917361 1 NC_008011.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 917361 hslV 4059690 hslV Lawsonia intracellularis PHE/MN1-00 ATP-dependent protease peptidase subunit YP_595107.1 916828 D 363253 CDS YP_595108.1 94987175 4059333 917632..918429 1 NC_008011.1 amino acid ABC transporter substrate-binding protein 918429 4059333 LI0733 Lawsonia intracellularis PHE/MN1-00 amino acid ABC transporter substrate-binding protein YP_595108.1 917632 D 363253 CDS YP_595109.1 94987176 4059334 918588..919070 1 NC_008011.1 hypothetical protein 919070 4059334 LI0734 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595109.1 918588 D 363253 CDS YP_595110.1 94987177 4059619 919170..920087 1 NC_008011.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 920087 ychB 4059619 ychB Lawsonia intracellularis PHE/MN1-00 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_595110.1 919170 D 363253 CDS YP_595111.1 94987178 4059983 920202..921167 1 NC_008011.1 phosphoribosylpyrophosphate synthetase 921167 prsA 4059983 prsA Lawsonia intracellularis PHE/MN1-00 phosphoribosylpyrophosphate synthetase YP_595111.1 920202 D 363253 CDS YP_595112.1 94987179 4059335 921211..921804 1 NC_008011.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 921804 4059335 LI0737 Lawsonia intracellularis PHE/MN1-00 50S ribosomal protein L25 YP_595112.1 921211 D 363253 CDS YP_595113.1 94987180 4059336 921880..922485 1 NC_008011.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 922485 4059336 LI0738 Lawsonia intracellularis PHE/MN1-00 peptidyl-tRNA hydrolase YP_595113.1 921880 D 363253 CDS YP_595114.1 94987181 4059337 922741..923433 1 NC_008011.1 hypothetical protein 923433 4059337 LI0739 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595114.1 922741 D 363253 CDS YP_595115.1 94987182 4059724 923583..924377 1 NC_008011.1 flagellar basal body rod protein 924377 flgF 4059724 flgF Lawsonia intracellularis PHE/MN1-00 flagellar basal body rod protein YP_595115.1 923583 D 363253 CDS YP_595116.1 94987183 4059725 924392..925177 1 NC_008011.1 makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 925177 flgG 4059725 flgG Lawsonia intracellularis PHE/MN1-00 flagellar basal body rod protein FlgG YP_595116.1 924392 D 363253 CDS YP_595117.1 94987184 4059338 925203..926186 1 NC_008011.1 hypothetical protein 926186 4059338 LI0742 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595117.1 925203 D 363253 CDS YP_595118.1 94987185 4059726 926204..926896 1 NC_008011.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar basal body L-ring protein 926896 flgH 4059726 flgH Lawsonia intracellularis PHE/MN1-00 flagellar basal body L-ring protein YP_595118.1 926204 D 363253 CDS YP_595119.1 94987186 4059727 926942..928081 1 NC_008011.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein 928081 flgI 4059727 flgI Lawsonia intracellularis PHE/MN1-00 flagellar basal body P-ring protein YP_595119.1 926942 D 363253 CDS YP_595120.1 94987187 4059728 928086..928769 1 NC_008011.1 membrane proteins related to metalloendopeptidases 928769 flgJ 4059728 flgJ Lawsonia intracellularis PHE/MN1-00 membrane proteins related to metalloendopeptidases YP_595120.1 928086 D 363253 CDS YP_595121.1 94987188 4059339 928976..929506 1 NC_008011.1 hypothetical protein 929506 4059339 LI0746 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595121.1 928976 D 363253 CDS YP_595122.1 94987189 4059729 929506..931623 1 NC_008011.1 flagellar hook-associated protein 931623 flgK 4059729 flgK Lawsonia intracellularis PHE/MN1-00 flagellar hook-associated protein YP_595122.1 929506 D 363253 CDS YP_595123.1 94987190 4059730 931633..933210 1 NC_008011.1 flagellin-like protein 933210 flgL 4059730 flgL Lawsonia intracellularis PHE/MN1-00 flagellin-like protein YP_595123.1 931633 D 363253 CDS YP_595124.1 94987191 4059340 933304..933993 1 NC_008011.1 binds to flagellin and appears to stabilize flagellin during flagella assembly; flagellar assembly protein FliW 933993 4059340 LI0749 Lawsonia intracellularis PHE/MN1-00 flagellar assembly protein FliW YP_595124.1 933304 D 363253 CDS YP_595125.1 94987192 4059341 934221..935801 1 NC_008011.1 hypothetical protein 935801 4059341 LI0750 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595125.1 934221 D 363253 CDS YP_595126.1 94987193 4059342 complement(935839..937368) 1 NC_008011.1 Mg chelatase-related protein 937368 4059342 LI0751 Lawsonia intracellularis PHE/MN1-00 Mg chelatase-related protein YP_595126.1 935839 R 363253 CDS YP_595127.1 94987194 4059343 complement(937365..939059) 1 NC_008011.1 Sulfate transporter family protein 939059 4059343 LI0752 Lawsonia intracellularis PHE/MN1-00 Sulfate transporter family protein YP_595127.1 937365 R 363253 CDS YP_595128.1 94987195 4060213 complement(939166..939858) 1 NC_008011.1 ABC-type amino acid transport system, permease component 939858 glnP 4060213 glnP Lawsonia intracellularis PHE/MN1-00 ABC-type amino acid transport system, permease component YP_595128.1 939166 R 363253 CDS YP_595129.1 94987196 4060210 complement(939981..940730) 1 NC_008011.1 amino acid ABC transporter substrate-binding protein 940730 glnH 4060210 glnH Lawsonia intracellularis PHE/MN1-00 amino acid ABC transporter substrate-binding protein YP_595129.1 939981 R 363253 CDS YP_595130.1 94987197 4060142 complement(941271..942995) 1 NC_008011.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 942995 rpsA 4060142 rpsA Lawsonia intracellularis PHE/MN1-00 30S ribosomal protein S1 YP_595130.1 941271 R 363253 CDS YP_595131.1 94987198 4059909 complement(943310..943795) 1 NC_008011.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 943795 rnhA 4059909 rnhA Lawsonia intracellularis PHE/MN1-00 ribonuclease H YP_595131.1 943310 R 363253 CDS YP_595132.1 94987199 4060149 complement(943971..944864) 1 NC_008011.1 hypothetical protein 944864 menA 4060149 menA Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595132.1 943971 R 363253 CDS YP_595133.1 94987200 4059344 complement(944976..945602) 1 NC_008011.1 hypothetical protein 945602 4059344 LI0758 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595133.1 944976 R 363253 CDS YP_595134.1 94987201 4060150 complement(945599..946513) 1 NC_008011.1 hypothetical protein 946513 menA 4060150 menA Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595134.1 945599 R 363253 CDS YP_595135.1 94987202 4059827 complement(946612..947238) 1 NC_008011.1 thymidylate kinase 947238 tmk 4059827 tmk Lawsonia intracellularis PHE/MN1-00 thymidylate kinase YP_595135.1 946612 R 363253 CDS YP_595136.1 94987203 4060404 complement(947223..948281) 1 NC_008011.1 HD-superfamily hydrolase 948281 cbf1 4060404 cbf1 Lawsonia intracellularis PHE/MN1-00 HD-superfamily hydrolase YP_595136.1 947223 R 363253 CDS YP_595137.1 94987204 4059808 948405..949160 1 NC_008011.1 acid phosphatase 949160 surE 4059808 surE Lawsonia intracellularis PHE/MN1-00 acid phosphatase YP_595137.1 948405 D 363253 CDS YP_595138.1 94987205 4059308 949353..950276 1 NC_008011.1 fructose/tagatose bisphosphate aldolase 950276 fba 4059308 fba Lawsonia intracellularis PHE/MN1-00 fructose/tagatose bisphosphate aldolase YP_595138.1 949353 D 363253 CDS YP_595139.1 94987206 4060318 950386..951387 1 NC_008011.1 glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase 951387 gapA 4060318 gapA Lawsonia intracellularis PHE/MN1-00 glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase YP_595139.1 950386 D 363253 CDS YP_595140.1 94987207 4059345 complement(951412..952311) 1 NC_008011.1 hypothetical protein 952311 4059345 LI0765 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595140.1 951412 R 363253 CDS YP_595141.1 94987208 4059748 complement(952368..953336) 1 NC_008011.1 methionyl-tRNA formyltransferase 953336 fmt 4059748 fmt Lawsonia intracellularis PHE/MN1-00 methionyl-tRNA formyltransferase YP_595141.1 952368 R 363253 CDS YP_595142.1 94987209 4060372 complement(953333..953848) 1 NC_008011.1 N-formylmethionyl-tRNA deformylase 953848 def 4060372 def Lawsonia intracellularis PHE/MN1-00 N-formylmethionyl-tRNA deformylase YP_595142.1 953333 R 363253 CDS YP_595143.1 94987210 4060057 954008..955000 1 NC_008011.1 tRNA-dihydrouridine synthase 955000 nifr3 4060057 nifr3 Lawsonia intracellularis PHE/MN1-00 tRNA-dihydrouridine synthase YP_595143.1 954008 D 363253 CDS YP_595144.1 94987211 4059346 complement(955017..955769) 1 NC_008011.1 hypothetical protein 955769 4059346 LI0769 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595144.1 955017 R 363253 CDS YP_595145.1 94987212 4059347 complement(955760..956341) 1 NC_008011.1 5-formyltetrahydrofolate cyclo-ligase 956341 4059347 LI0770 Lawsonia intracellularis PHE/MN1-00 5-formyltetrahydrofolate cyclo-ligase YP_595145.1 955760 R 363253 CDS YP_595146.1 94987213 4059908 957340..959340 1 NC_008011.1 ribonucleases G and E 959340 rne 4059908 rne Lawsonia intracellularis PHE/MN1-00 ribonucleases G and E YP_595146.1 957340 D 363253 CDS YP_595147.1 94987214 4059348 959344..959937 1 NC_008011.1 hypothetical protein 959937 4059348 LI0772 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595147.1 959344 D 363253 CDS YP_595148.1 94987215 4059677 complement(959970..961946) 1 NC_008011.1 Kef-type K+ transport systems, membrane components 961946 kefC 4059677 kefC Lawsonia intracellularis PHE/MN1-00 Kef-type K+ transport systems, membrane components YP_595148.1 959970 R 363253 CDS YP_595149.1 94987216 4059833 962215..963630 1 NC_008011.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane component 963630 trkA 4059833 trkA Lawsonia intracellularis PHE/MN1-00 potassium transporter peripheral membrane component YP_595149.1 962215 D 363253 CDS YP_595150.1 94987217 4059834 963721..965187 1 NC_008011.1 Trk-type K+ transport systems, membrane components 965187 trkH 4059834 trkH Lawsonia intracellularis PHE/MN1-00 Trk-type K+ transport systems, membrane components YP_595150.1 963721 D 363253 CDS YP_595151.1 94987218 4059984 965279..965941 1 NC_008011.1 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine; phosphatidylserine decarboxylase 965941 psd 4059984 psd Lawsonia intracellularis PHE/MN1-00 phosphatidylserine decarboxylase YP_595151.1 965279 D 363253 CDS YP_595152.1 94987219 4059349 966003..966752 1 NC_008011.1 phosphatidylserine synthase 966752 4059349 LI0777 Lawsonia intracellularis PHE/MN1-00 phosphatidylserine synthase YP_595152.1 966003 D 363253 CDS YP_595153.1 94987220 4060065 complement(966810..967460) 1 NC_008011.1 endonuclease III 967460 nth 4060065 nth Lawsonia intracellularis PHE/MN1-00 endonuclease III YP_595153.1 966810 R 363253 CDS YP_595154.1 94987221 4060437 967580..967900 1 NC_008011.1 divalent cation tolerance protein 967900 cutA 4060437 cutA Lawsonia intracellularis PHE/MN1-00 divalent cation tolerance protein YP_595154.1 967580 D 363253 CDS YP_595155.1 94987222 4059753 967901..968842 1 NC_008011.1 ribokinase family sugar kinase 968842 fruK 4059753 fruK Lawsonia intracellularis PHE/MN1-00 ribokinase family sugar kinase YP_595155.1 967901 D 363253 CDS YP_595156.1 94987223 4059350 969129..970853 1 NC_008011.1 5-enolpyruvylshikimate-3-phosphate synthase 970853 4059350 LI0781 Lawsonia intracellularis PHE/MN1-00 5-enolpyruvylshikimate-3-phosphate synthase YP_595156.1 969129 D 363253 CDS YP_595157.1 94987224 4059817 970873..971706 1 NC_008011.1 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 971706 thiD 4059817 thiD Lawsonia intracellularis PHE/MN1-00 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase YP_595157.1 970873 D 363253 CDS YP_595158.1 94987225 4059351 complement(972160..972975) 1 NC_008011.1 hypothetical protein 972975 4059351 LI0783 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595158.1 972160 R 363253 CDS YP_595159.1 94987226 4060258 complement(973029..975491) 1 NC_008011.1 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit 975491 gyrA 4060258 gyrA Lawsonia intracellularis PHE/MN1-00 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit YP_595159.1 973029 R 363253 CDS YP_595160.1 94987227 4060259 complement(975610..978009) 1 NC_008011.1 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit 978009 gyrB 4060259 gyrB Lawsonia intracellularis PHE/MN1-00 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit YP_595160.1 975610 R 363253 CDS YP_595161.1 94987228 4060381 complement(978042..979193) 1 NC_008011.1 DNA polymerase sliding clamp subunit (PCNA homolog) 979193 dnaN 4060381 dnaN Lawsonia intracellularis PHE/MN1-00 DNA polymerase sliding clamp subunit (PCNA homolog) YP_595161.1 978042 R 363253 CDS YP_595162.1 94987229 4060375 complement(979314..980636) 1 NC_008011.1 DNA replication initiation ATPase 980636 dnaA 4060375 dnaA Lawsonia intracellularis PHE/MN1-00 DNA replication initiation ATPase YP_595162.1 979314 R 363253 CDS YP_595163.1 94987230 4059352 980888..982222 1 NC_008011.1 membrane proteins related to metalloendopeptidases 982222 4059352 LI0788 Lawsonia intracellularis PHE/MN1-00 membrane proteins related to metalloendopeptidases YP_595163.1 980888 D 363253 CDS YP_595164.1 94987231 4059935 982255..983355 1 NC_008011.1 S-adenosylmethionine:tRNA-ribosyltransferase- isomerase (queuine synthetase) 983355 queA 4059935 queA Lawsonia intracellularis PHE/MN1-00 S-adenosylmethionine:tRNA-ribosyltransferase- isomerase (queuine synthetase) YP_595164.1 982255 D 363253 CDS YP_595165.1 94987232 4059612 984330..985391 1 NC_008011.1 catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA; 2-ketoisovalerate ferredoxin reductase 985391 vorB 4059612 vorB Lawsonia intracellularis PHE/MN1-00 2-ketoisovalerate ferredoxin reductase YP_595165.1 984330 D 363253 CDS YP_595166.1 94987233 4060005 985391..986194 1 NC_008011.1 ferredoxin oxidoreductases, beta subunit 986194 porB 4060005 porB Lawsonia intracellularis PHE/MN1-00 ferredoxin oxidoreductases, beta subunit YP_595166.1 985391 D 363253 CDS YP_595167.1 94987234 4060006 986196..986738 1 NC_008011.1 ferredoxin oxidoreductases, gamma subunit 986738 porB 4060006 porB Lawsonia intracellularis PHE/MN1-00 ferredoxin oxidoreductases, gamma subunit YP_595167.1 986196 D 363253 CDS YP_595168.1 94987235 4059353 987288..988580 1 NC_008011.1 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) 988580 4059353 LI0793 Lawsonia intracellularis PHE/MN1-00 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) YP_595168.1 987288 D 363253 CDS YP_595169.1 94987236 4060426 988737..989366 1 NC_008011.1 protease subunit of ATP-dependent Clp proteases 989366 clpP 4060426 clpP Lawsonia intracellularis PHE/MN1-00 protease subunit of ATP-dependent Clp proteases YP_595169.1 988737 D 363253 CDS YP_595170.1 94987237 4060427 989642..990895 1 NC_008011.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 990895 clpX 4060427 clpX Lawsonia intracellularis PHE/MN1-00 ATP-dependent protease ATP-binding subunit ClpX YP_595170.1 989642 D 363253 CDS YP_595171.1 94987238 4059662 990983..993436 1 NC_008011.1 ATP-dependent protease 993436 lon 4059662 lon Lawsonia intracellularis PHE/MN1-00 ATP-dependent protease YP_595171.1 990983 D 363253 CDS YP_595172.1 94987239 4059354 complement(993461..993847) 1 NC_008011.1 hypothetical protein 993847 4059354 LI0797 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595172.1 993461 R 363253 CDS YP_595173.1 94987240 4059355 994282..995271 1 NC_008011.1 hypothetical protein 995271 4059355 LI0798 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595173.1 994282 D 363253 CDS YP_595174.1 94987241 4059455 complement(995278..995916) 1 NC_008011.1 hypothetical protein 995916 4059455 LI0799 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595174.1 995278 R 363253 CDS YP_595175.1 94987242 4059456 complement(995965..996681) 1 NC_008011.1 hypothetical protein 996681 4059456 LI0800 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595175.1 995965 R 363253 CDS YP_595176.1 94987243 4060328 996842..998215 1 NC_008011.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 998215 glmU 4060328 glmU Lawsonia intracellularis PHE/MN1-00 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_595176.1 996842 D 363253 CDS YP_595177.1 94987244 4059457 999188..1000750 1 NC_008011.1 protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP; phosphodiesterase 1000750 4059457 LI0802 Lawsonia intracellularis PHE/MN1-00 phosphodiesterase YP_595177.1 999188 D 363253 CDS YP_595178.1 94987245 4059458 1000833..1001591 1 NC_008011.1 hypothetical protein 1001591 4059458 LI0803 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595178.1 1000833 D 363253 CDS YP_595179.1 94987246 4059459 complement(1001682..1002140) 1 NC_008011.1 hypothetical protein 1002140 4059459 LI0804 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595179.1 1001682 R 363253 CDS YP_595180.1 94987247 4059460 complement(1002133..1002810) 1 NC_008011.1 hypothetical protein 1002810 4059460 LI0805 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595180.1 1002133 R 363253 CDS YP_595181.1 94987248 4060113 complement(1002865..1003953) 1 NC_008011.1 O-succinylbenzoic acid--CoA ligase 1003953 menE 4060113 menE Lawsonia intracellularis PHE/MN1-00 O-succinylbenzoic acid--CoA ligase YP_595181.1 1002865 R 363253 CDS YP_595182.1 94987249 4060112 complement(1004052..1004873) 1 NC_008011.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase 1004873 menB 4060112 menB Lawsonia intracellularis PHE/MN1-00 naphthoate synthase YP_595182.1 1004052 R 363253 CDS YP_595183.1 94987250 4060432 complement(1004883..1005317) 1 NC_008011.1 hydrolase, haloacid dehalogenase-like hydrolase 1005317 comA 4060432 comA Lawsonia intracellularis PHE/MN1-00 hydrolase, haloacid dehalogenase-like hydrolase YP_595183.1 1004883 R 363253 CDS YP_595184.1 94987251 4059461 complement(1005673..1006062) 1 NC_008011.1 hypothetical protein 1006062 4059461 LI0809 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595184.1 1005673 R 363253 CDS YP_595185.1 94987252 4059462 1006385..1007098 1 NC_008011.1 integral membrane protein, interacts with FtsH 1007098 4059462 LI0810 Lawsonia intracellularis PHE/MN1-00 integral membrane protein, interacts with FtsH YP_595185.1 1006385 D 363253 CDS YP_595186.1 94987253 4059999 complement(1007157..1008167) 1 NC_008011.1 phosphate/sulphate permeases 1008167 pit 4059999 pit Lawsonia intracellularis PHE/MN1-00 phosphate/sulphate permeases YP_595186.1 1007157 R 363253 CDS YP_595187.1 94987254 4059463 complement(1008160..1008795) 1 NC_008011.1 hypothetical protein 1008795 4059463 LI0812 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595187.1 1008160 R 363253 CDS YP_595188.1 94987255 4059904 1010184..1011809 1 NC_008011.1 pseudouridylate synthase 1011809 rluD 4059904 rluD Lawsonia intracellularis PHE/MN1-00 pseudouridylate synthase YP_595188.1 1010184 D 363253 CDS YP_595189.1 94987256 4059804 1012019..1012804 1 NC_008011.1 chromosome partitioning ATPase 1012804 soj 4059804 soj Lawsonia intracellularis PHE/MN1-00 chromosome partitioning ATPase YP_595189.1 1012019 D 363253 CDS YP_595190.1 94987257 4059806 1012884..1013843 1 NC_008011.1 transcriptional regulator 1013843 spo0J 4059806 spo0J Lawsonia intracellularis PHE/MN1-00 transcriptional regulator YP_595190.1 1012884 D 363253 CDS YP_595191.1 94987258 4059464 1013959..1014996 1 NC_008011.1 ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase 1014996 4059464 LI0816 Lawsonia intracellularis PHE/MN1-00 ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase YP_595191.1 1013959 D 363253 CDS YP_595192.1 94987259 4060265 complement(1015004..1016197) 1 NC_008011.1 coproporphyrinogen III oxidase-like protein 1016197 hemN 4060265 hemN Lawsonia intracellularis PHE/MN1-00 coproporphyrinogen III oxidase-like protein YP_595192.1 1015004 R 363253 CDS YP_595193.1 94987260 4059964 1016534..1017481 1 NC_008011.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase 1017481 pyrB 4059964 pyrB Lawsonia intracellularis PHE/MN1-00 aspartate carbamoyltransferase YP_595193.1 1016534 D 363253 CDS YP_595194.1 94987261 4059965 1017493..1018764 1 NC_008011.1 dihydroorotase-like protein 1018764 pyrC 4059965 pyrC Lawsonia intracellularis PHE/MN1-00 dihydroorotase-like protein YP_595194.1 1017493 D 363253 CDS YP_595195.1 94987262 4059465 complement(1018869..1019642) 1 NC_008011.1 2-keto-4-pentenoate hydratase 1019642 4059465 LI0820 Lawsonia intracellularis PHE/MN1-00 2-keto-4-pentenoate hydratase YP_595195.1 1018869 R 363253 CDS YP_595196.1 94987263 4060119 1019930..1021303 1 NC_008011.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 1021303 miaB 4060119 miaB Lawsonia intracellularis PHE/MN1-00 (dimethylallyl)adenosine tRNA methylthiotransferase YP_595196.1 1019930 D 363253 CDS YP_595197.1 94987264 4059466 1021458..1022141 1 NC_008011.1 PHP family histidinol phosphatase/hydrolase 1022141 4059466 LI0822 Lawsonia intracellularis PHE/MN1-00 PHP family histidinol phosphatase/hydrolase YP_595197.1 1021458 D 363253 CDS YP_595198.1 94987265 4060029 1022176..1023267 1 NC_008011.1 Xaa-Pro aminopeptidase 1023267 pepQ 4060029 pepQ Lawsonia intracellularis PHE/MN1-00 Xaa-Pro aminopeptidase YP_595198.1 1022176 D 363253 CDS YP_595199.1 94987266 4059467 1023291..1024349 1 NC_008011.1 glycosyltransferase 1024349 4059467 LI0824 Lawsonia intracellularis PHE/MN1-00 glycosyltransferase YP_595199.1 1023291 D 363253 CDS YP_595200.1 94987267 4059468 1024378..1025664 1 NC_008011.1 Lipid A core-O-antigen ligase and related enzymes 1025664 4059468 LI0825 Lawsonia intracellularis PHE/MN1-00 Lipid A core-O-antigen ligase and related enzymes YP_595200.1 1024378 D 363253 CDS YP_595201.1 94987268 4059840 complement(1025679..1025888) 1 NC_008011.1 required for 70S ribosome assembly; 50S ribosomal protein L28 1025888 rpmB 4059840 rpmB Lawsonia intracellularis PHE/MN1-00 50S ribosomal protein L28 YP_595201.1 1025679 R 363253 CDS YP_595202.1 94987269 4059469 1026067..1028082 1 NC_008011.1 lipoprotein 1028082 4059469 LI0827 Lawsonia intracellularis PHE/MN1-00 lipoprotein YP_595202.1 1026067 D 363253 CDS YP_595203.1 94987270 4060252 complement(1028105..1029172) 1 NC_008011.1 glycerol-3-phosphate dehydrogenase 1029172 gpsA 4060252 gpsA Lawsonia intracellularis PHE/MN1-00 glycerol-3-phosphate dehydrogenase YP_595203.1 1028105 R 363253 CDS YP_595204.1 94987271 4060007 1029763..1030869 1 NC_008011.1 functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase 1030869 potA 4060007 potA Lawsonia intracellularis PHE/MN1-00 putrescine/spermidine ABC transporter ATPase YP_595204.1 1029763 D 363253 CDS YP_595205.1 94987272 4060008 1030856..1031740 1 NC_008011.1 ABC-type spermidine/putrescine transport system, permease component I 1031740 potB 4060008 potB Lawsonia intracellularis PHE/MN1-00 ABC-type spermidine/putrescine transport system, permease component I YP_595205.1 1030856 D 363253 CDS YP_595206.1 94987273 4060009 1031740..1032516 1 NC_008011.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein 1032516 potC 4060009 potC Lawsonia intracellularis PHE/MN1-00 spermidine/putrescine ABC transporter membrane protein YP_595206.1 1031740 D 363253 CDS YP_595207.1 94987274 4060010 1032574..1033626 1 NC_008011.1 spermidine/putrescine-binding periplasmic protein 1033626 potD 4060010 potD Lawsonia intracellularis PHE/MN1-00 spermidine/putrescine-binding periplasmic protein YP_595207.1 1032574 D 363253 CDS YP_595208.1 94987275 4059470 complement(1033802..1035070) 1 NC_008011.1 hypothetical protein 1035070 4059470 LI0833 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595208.1 1033802 R 363253 CDS YP_595209.1 94987276 4059471 complement(1035090..1035533) 1 NC_008011.1 hypothetical protein 1035533 4059471 LI0834 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595209.1 1035090 R 363253 CDS YP_595210.1 94987277 4059472 complement(1035578..1036222) 1 NC_008011.1 hypothetical protein 1036222 4059472 LI0835 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595210.1 1035578 R 363253 CDS YP_595211.1 94987278 4059473 1036458..1037198 1 NC_008011.1 transcriptional regulator 1037198 4059473 LI0836 Lawsonia intracellularis PHE/MN1-00 transcriptional regulator YP_595211.1 1036458 D 363253 CDS YP_595212.1 94987279 4059395 1037498..1040206 1 NC_008011.1 hypothetical protein 1040206 4059395 LI0837 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595212.1 1037498 D 363253 CDS YP_595213.1 94987280 4060074 complement(1040246..1041496) 1 NC_008011.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1041496 murA 4060074 murA Lawsonia intracellularis PHE/MN1-00 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_595213.1 1040246 R 363253 CDS YP_595214.1 94987281 4059615 complement(1041779..1042558) 1 NC_008011.1 exonuclease III 1042558 xthA 4059615 xthA Lawsonia intracellularis PHE/MN1-00 exonuclease III YP_595214.1 1041779 R 363253 CDS YP_595215.1 94987282 4059396 complement(1042878..1043369) 1 NC_008011.1 hypothetical protein 1043369 4059396 LI0840 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595215.1 1042878 R 363253 CDS YP_595216.1 94987283 4059397 complement(1043947..1044681) 1 NC_008011.1 invasin 1044681 4059397 LI0841 Lawsonia intracellularis PHE/MN1-00 invasin YP_595216.1 1043947 R 363253 CDS YP_595217.1 94987284 4059673 1045546..1047813 1 NC_008011.1 Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide; hydroperoxidase II 1047813 katE 4059673 katE Lawsonia intracellularis PHE/MN1-00 hydroperoxidase II YP_595217.1 1045546 D 363253 CDS YP_595218.1 94987285 4059505 1048872..1050629 1 NC_008011.1 methyl-accepting chemotaxis protein 1050629 tsr 4059505 tsr Lawsonia intracellularis PHE/MN1-00 methyl-accepting chemotaxis protein YP_595218.1 1048872 D 363253 CDS YP_595219.1 94987286 4059398 complement(1050746..1052017) 1 NC_008011.1 tRNA and rRNA cytosine-C5-methylases 1052017 4059398 LI0844 Lawsonia intracellularis PHE/MN1-00 tRNA and rRNA cytosine-C5-methylases YP_595219.1 1050746 R 363253 CDS YP_595220.1 94987287 4059399 1052160..1053803 1 NC_008011.1 hypothetical protein 1053803 4059399 LI0845 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595220.1 1052160 D 363253 CDS YP_595221.1 94987288 4059400 1053988..1055109 1 NC_008011.1 lipopolysaccharide core biosynthesis protein RfaG (glucosyltransferase I) 1055109 4059400 LI0846 Lawsonia intracellularis PHE/MN1-00 lipopolysaccharide core biosynthesis protein RfaG (glucosyltransferase I) YP_595221.1 1053988 D 363253 CDS YP_595222.1 94987289 4059401 1055274..1056068 1 NC_008011.1 hypothetical protein 1056068 4059401 LI0847 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595222.1 1055274 D 363253 CDS YP_595223.1 94987290 4060322 complement(1056140..1057477) 1 NC_008011.1 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; tRNA (uracil-5-)-methyltransferase Gid 1057477 gidA 4060322 gidA Lawsonia intracellularis PHE/MN1-00 tRNA (uracil-5-)-methyltransferase Gid YP_595223.1 1056140 R 363253 CDS YP_595224.1 94987291 4059402 complement(1057662..1058297) 1 NC_008011.1 HD superfamily hydrolase 1058297 4059402 LI0849 Lawsonia intracellularis PHE/MN1-00 HD superfamily hydrolase YP_595224.1 1057662 R 363253 CDS YP_595225.1 94987292 4059403 complement(1058349..1059566) 1 NC_008011.1 hypothetical protein 1059566 4059403 LI0850 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595225.1 1058349 R 363253 CDS YP_595226.1 94987293 4059404 1059742..1060068 1 NC_008011.1 NAD(P)H-dependent flavin reductase 1060068 4059404 LI0851 Lawsonia intracellularis PHE/MN1-00 NAD(P)H-dependent flavin reductase YP_595226.1 1059742 D 363253 CDS YP_595227.1 94987294 4059405 1060120..1060419 1 NC_008011.1 NAD(P)H nitroreductase 1060419 4059405 LI0852 Lawsonia intracellularis PHE/MN1-00 NAD(P)H nitroreductase YP_595227.1 1060120 D 363253 CDS YP_595228.1 94987295 4059406 complement(1060422..1060829) 1 NC_008011.1 redox protein, regulator of disulfide bond formation 1060829 4059406 LI0853 Lawsonia intracellularis PHE/MN1-00 redox protein, regulator of disulfide bond formation YP_595228.1 1060422 R 363253 CDS YP_595229.1 94987296 4059741 complement(1062640..1063959) 1 NC_008011.1 flagellar biosynthesis/type III secretory pathway ATPase 1063959 fliI 4059741 fliI Lawsonia intracellularis PHE/MN1-00 flagellar biosynthesis/type III secretory pathway ATPase YP_595229.1 1062640 R 363253 CDS YP_595230.1 94987297 4059407 complement(1063984..1065429) 1 NC_008011.1 flagellar biosynthesis/type III secretory pathway protein 1065429 4059407 LI0855 Lawsonia intracellularis PHE/MN1-00 flagellar biosynthesis/type III secretory pathway protein YP_595230.1 1063984 R 363253 CDS YP_595231.1 94987298 4059740 complement(1065476..1066471) 1 NC_008011.1 flagellar motor switch protein 1066471 fliG 4059740 fliG Lawsonia intracellularis PHE/MN1-00 flagellar motor switch protein YP_595231.1 1065476 R 363253 CDS YP_595232.1 94987299 4059739 complement(1066878..1068542) 1 NC_008011.1 flagellar biosynthesis/type III secretory pathway lipoprotein 1068542 fliF 4059739 fliF Lawsonia intracellularis PHE/MN1-00 flagellar biosynthesis/type III secretory pathway lipoprotein YP_595232.1 1066878 R 363253 CDS YP_595233.1 94987300 4059738 complement(1068655..1069002) 1 NC_008011.1 flagellar hook-basal body protein 1069002 fliE 4059738 fliE Lawsonia intracellularis PHE/MN1-00 flagellar hook-basal body protein YP_595233.1 1068655 R 363253 CDS YP_595234.1 94987301 4059316 complement(1069051..1069491) 1 NC_008011.1 flagellar basal body rod protein 1069491 flgC 4059316 flgC Lawsonia intracellularis PHE/MN1-00 flagellar basal body rod protein YP_595234.1 1069051 R 363253 CDS YP_595235.1 94987302 4059315 complement(1069494..1069907) 1 NC_008011.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgB 1069907 flgB 4059315 flgB Lawsonia intracellularis PHE/MN1-00 flagellar basal body rod protein FlgB YP_595235.1 1069494 R 363253 CDS YP_595236.1 94987303 4060406 complement(1070196..1070954) 1 NC_008011.1 ABC-type cobalt transport system, ATPase component 1070954 cbiO 4060406 cbiO Lawsonia intracellularis PHE/MN1-00 ABC-type cobalt transport system, ATPase component YP_595236.1 1070196 R 363253 CDS YP_595237.1 94987304 4059408 complement(1070963..1071709) 1 NC_008011.1 hypothetical protein 1071709 4059408 LI0862 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595237.1 1070963 R 363253 CDS YP_595238.1 94987305 4060405 complement(1071699..1072334) 1 NC_008011.1 catalyzes the ATP-dependent transport of cobalt; cobalt transport protein CbiM 1072334 cbiM 4060405 cbiM Lawsonia intracellularis PHE/MN1-00 cobalt transport protein CbiM YP_595238.1 1071699 R 363253 CDS YP_595239.1 94987306 4059409 complement(1072321..1072818) 1 NC_008011.1 hypothetical protein 1072818 4059409 LI0864 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595239.1 1072321 R 363253 CDS YP_595240.1 94987307 4060086 complement(1073007..1074569) 1 NC_008011.1 uncharacterized membrane protein, virulence factor 1074569 mviN 4060086 mviN Lawsonia intracellularis PHE/MN1-00 uncharacterized membrane protein, virulence factor YP_595240.1 1073007 R 363253 CDS YP_595241.1 94987308 4059410 complement(1074655..1076736) 1 NC_008011.1 membrane metal-binding protein 1076736 4059410 LI0866 Lawsonia intracellularis PHE/MN1-00 membrane metal-binding protein YP_595241.1 1074655 R 363253 CDS YP_595242.1 94987309 4060080 complement(1077738..1078598) 1 NC_008011.1 glutamate racemase 1078598 murI 4060080 murI Lawsonia intracellularis PHE/MN1-00 glutamate racemase YP_595242.1 1077738 R 363253 CDS YP_595243.1 94987310 4059902 complement(1078883..1079695) 1 NC_008011.1 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases 1079695 rluB 4059902 rluB Lawsonia intracellularis PHE/MN1-00 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases YP_595243.1 1078883 R 363253 CDS YP_595244.1 94987311 4059411 1079867..1081684 1 NC_008011.1 ABC-type multidrug transport system, ATPase and permease components 1081684 4059411 LI0869 Lawsonia intracellularis PHE/MN1-00 ABC-type multidrug transport system, ATPase and permease components YP_595244.1 1079867 D 363253 CDS YP_595245.1 94987312 4059412 1081659..1082303 1 NC_008011.1 hypothetical protein 1082303 4059412 LI0870 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595245.1 1081659 D 363253 CDS YP_595246.1 94987313 4059693 1082307..1083191 1 NC_008011.1 acyltransferase 1083191 htrB 4059693 htrB Lawsonia intracellularis PHE/MN1-00 acyltransferase YP_595246.1 1082307 D 363253 CDS YP_595247.1 94987314 4059413 complement(1083991..1085361) 1 NC_008011.1 hypothetical protein 1085361 4059413 LI0872 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595247.1 1083991 R 363253 CDS YP_595248.1 94987315 4059414 complement(1085499..1086062) 1 NC_008011.1 ACT domain-containing protein 1086062 4059414 LI0873 Lawsonia intracellularis PHE/MN1-00 ACT domain-containing protein YP_595248.1 1085499 R 363253 CDS YP_595249.1 94987316 4059356 1086267..1088042 1 NC_008011.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase 1088042 4059356 LI0874 Lawsonia intracellularis PHE/MN1-00 formate--tetrahydrofolate ligase YP_595249.1 1086267 D 363253 CDS YP_595250.1 94987317 4059357 1088081..1088974 1 NC_008011.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 1088974 4059357 LI0875 Lawsonia intracellularis PHE/MN1-00 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_595250.1 1088081 D 363253 CDS YP_595251.1 94987318 4059358 complement(1088986..1090329) 1 NC_008011.1 tRNA and rRNA cytosine-C5-methylases 1090329 4059358 LI0876 Lawsonia intracellularis PHE/MN1-00 tRNA and rRNA cytosine-C5-methylases YP_595251.1 1088986 R 363253 CDS YP_595252.1 94987319 4059389 complement(1090388..1091761) 1 NC_008011.1 response regulator 1091761 atoC 4059389 atoC Lawsonia intracellularis PHE/MN1-00 response regulator YP_595252.1 1090388 R 363253 CDS YP_595253.1 94987320 4059390 complement(1091827..1093269) 1 NC_008011.1 Signal transduction histidine kinase 1093269 atoS 4059390 atoS Lawsonia intracellularis PHE/MN1-00 Signal transduction histidine kinase YP_595253.1 1091827 R 363253 CDS YP_595254.1 94987321 4060032 complement(1093271..1094605) 1 NC_008011.1 glucose-6-phosphate isomerase 1094605 pgi 4060032 pgi Lawsonia intracellularis PHE/MN1-00 glucose-6-phosphate isomerase YP_595254.1 1093271 R 363253 CDS YP_595255.1 94987322 4059799 1095072..1095860 1 NC_008011.1 DNA-binding protein, stimulates sugar fermentation 1095860 sfsA 4059799 sfsA Lawsonia intracellularis PHE/MN1-00 DNA-binding protein, stimulates sugar fermentation YP_595255.1 1095072 D 363253 CDS YP_595256.1 94987323 4059359 complement(1095872..1096972) 1 NC_008011.1 permease 1096972 4059359 LI0881 Lawsonia intracellularis PHE/MN1-00 permease YP_595256.1 1095872 R 363253 CDS YP_595257.1 94987324 4059360 complement(1096969..1098123) 1 NC_008011.1 permease 1098123 4059360 LI0882 Lawsonia intracellularis PHE/MN1-00 permease YP_595257.1 1096969 R 363253 CDS YP_595258.1 94987325 4059361 complement(1098346..1099038) 1 NC_008011.1 Zn-dependent hydrolase 1099038 4059361 LI0883 Lawsonia intracellularis PHE/MN1-00 Zn-dependent hydrolase YP_595258.1 1098346 R 363253 CDS YP_595259.1 94987326 4059641 complement(1099356..1101281) 1 NC_008011.1 selenocysteine-specific translation elongation factor 1101281 selB 4059641 selB Lawsonia intracellularis PHE/MN1-00 selenocysteine-specific translation elongation factor YP_595259.1 1099356 R 363253 CDS YP_595260.1 94987327 4059362 complement(1101390..1102847) 1 NC_008011.1 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases 1102847 4059362 LI0885 Lawsonia intracellularis PHE/MN1-00 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases YP_595260.1 1101390 R 363253 CDS YP_595261.1 94987328 4059363 complement(<1102873..>1103156) 1 NC_008011.1 glutamyl-tRNA (Gln) amidotransferase subunit C >1103156 4059363 LI0886 Lawsonia intracellularis PHE/MN1-00 glutamyl-tRNA (Gln) amidotransferase subunit C YP_595261.1 <1102873 R 363253 CDS YP_595262.1 94987329 4059364 complement(1103384..1103869) 1 NC_008011.1 hypothetical protein 1103869 4059364 LI0887 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595262.1 1103384 R 363253 CDS YP_595263.1 94987330 4059365 1104132..1104584 1 NC_008011.1 universal stress protein UspA-like nucleotide-binding protein 1104584 4059365 LI0888 Lawsonia intracellularis PHE/MN1-00 universal stress protein UspA-like nucleotide-binding protein YP_595263.1 1104132 D 363253 CDS YP_595264.1 94987331 4059366 complement(1105139..1105771) 1 NC_008011.1 hypothetical protein 1105771 4059366 LI0889 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595264.1 1105139 R 363253 CDS YP_595265.1 94987332 4059367 complement(1106149..1110171) 1 NC_008011.1 hypothetical protein 1110171 4059367 LI0890 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595265.1 1106149 R 363253 CDS YP_595266.1 94987333 4059368 1111143..1111616 1 NC_008011.1 hypothetical protein 1111616 4059368 LI0891 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595266.1 1111143 D 363253 CDS YP_595267.1 94987334 4059658 1111705..1113402 1 NC_008011.1 Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 1113402 lnt 4059658 lnt Lawsonia intracellularis PHE/MN1-00 apolipoprotein N-acyltransferase YP_595267.1 1111705 D 363253 CDS YP_595268.1 94987335 4059369 1113451..1114539 1 NC_008011.1 protein chain release factor B 1114539 4059369 LI0893 Lawsonia intracellularis PHE/MN1-00 protein chain release factor B YP_595268.1 1113451 D 363253 CDS YP_595269.1 94987336 4059683 1114982..1115257 1 NC_008011.1 nucleoid DNA-binding protein 1115257 himD 4059683 himD Lawsonia intracellularis PHE/MN1-00 nucleoid DNA-binding protein YP_595269.1 1114982 D 363253 CDS YP_595270.1 94987337 4060370 1115585..1116430 1 NC_008011.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 1116430 dapF 4060370 dapF Lawsonia intracellularis PHE/MN1-00 diaminopimelate epimerase YP_595270.1 1115585 D 363253 CDS YP_595271.1 94987338 4060368 1116477..1117382 1 NC_008011.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 1117382 dapA 4060368 dapA Lawsonia intracellularis PHE/MN1-00 dihydrodipicolinate synthase YP_595271.1 1116477 D 363253 CDS YP_595272.1 94987339 4059375 1117584..1118747 1 NC_008011.1 member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers; MFS transport protein AraJ 1118747 araJ 4059375 araJ Lawsonia intracellularis PHE/MN1-00 MFS transport protein AraJ YP_595272.1 1117584 D 363253 CDS YP_595273.1 94987340 4059811 1118929..1119711 1 NC_008011.1 Mg-dependent DNase 1119711 tatD 4059811 tatD Lawsonia intracellularis PHE/MN1-00 Mg-dependent DNase YP_595273.1 1118929 D 363253 CDS YP_595274.1 94987341 4059370 complement(1119740..1120381) 1 NC_008011.1 hypothetical protein 1120381 4059370 LI0899 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595274.1 1119740 R 363253 CDS YP_595275.1 94987342 4059371 1120638..1121039 1 NC_008011.1 metal-dependent hydrolase 1121039 4059371 LI0900 Lawsonia intracellularis PHE/MN1-00 metal-dependent hydrolase YP_595275.1 1120638 D 363253 CDS YP_595276.1 94987343 4060385 1121253..1121570 1 NC_008011.1 sulfite reductase, dissimilatory-type gamma subunit 1121570 dsr 4060385 dsr Lawsonia intracellularis PHE/MN1-00 sulfite reductase, dissimilatory-type gamma subunit YP_595276.1 1121253 D 363253 CDS YP_595277.1 94987344 4059372 1121916..1122938 1 NC_008011.1 outer membrane protein 1122938 4059372 LI0902 Lawsonia intracellularis PHE/MN1-00 outer membrane protein YP_595277.1 1121916 D 363253 CDS YP_595278.1 94987345 4059373 1122971..1123441 1 NC_008011.1 hypothetical protein 1123441 4059373 LI0903 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595278.1 1122971 D 363253 CDS YP_595279.1 94987346 4059842 complement(1123545..1127711) 1 NC_008011.1 DNA-directed RNA polymerase, beta subunit/140 kD subunit 1127711 rpoB 4059842 rpoB Lawsonia intracellularis PHE/MN1-00 DNA-directed RNA polymerase, beta subunit/140 kD subunit YP_595279.1 1123545 R 363253 CDS YP_595280.1 94987347 4059843 complement(1127787..1131908) 1 NC_008011.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 1131908 rpoB 4059843 rpoB Lawsonia intracellularis PHE/MN1-00 DNA-directed RNA polymerase subunit beta YP_595280.1 1127787 R 363253 CDS YP_595281.1 94987348 4060263 complement(1132246..1133538) 1 NC_008011.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 1133538 hemL 4060263 hemL Lawsonia intracellularis PHE/MN1-00 glutamate-1-semialdehyde aminotransferase YP_595281.1 1132246 R 363253 CDS YP_595282.1 94987349 4060059 complement(1133538..1134038) 1 NC_008011.1 transcriptional regulators 1134038 nirH 4060059 nirH Lawsonia intracellularis PHE/MN1-00 transcriptional regulators YP_595282.1 1133538 R 363253 CDS YP_595283.1 94987350 4059663 1134626..1135717 1 NC_008011.1 hydrogenase maturation factor 1135717 hypD 4059663 hypD Lawsonia intracellularis PHE/MN1-00 hydrogenase maturation factor YP_595283.1 1134626 D 363253 CDS YP_003856777.1 304347694 9711828 complement(1136154..1136372) 1 NC_008011.1 translation initiation factor IF-1 1136372 9711828 LI_1200 Lawsonia intracellularis PHE/MN1-00 translation initiation factor IF-1 YP_003856777.1 1136154 R 363253 CDS YP_595284.1 94987351 4059646 complement(1136500..1137279) 1 NC_008011.1 prolipoprotein diacylglyceryl transferase 1137279 lgt 4059646 lgt Lawsonia intracellularis PHE/MN1-00 prolipoprotein diacylglyceryl transferase YP_595284.1 1136500 R 363253 CDS YP_595285.1 94987352 4060430 complement(1137481..1138158) 1 NC_008011.1 cytidylate kinase 1138158 cmk 4060430 cmk Lawsonia intracellularis PHE/MN1-00 cytidylate kinase YP_595285.1 1137481 R 363253 CDS YP_595286.1 94987353 4059374 complement(1138388..1139284) 1 NC_008011.1 hypothetical protein 1139284 4059374 LI0911 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595286.1 1138388 R 363253 CDS YP_595287.1 94987354 4060380 1139678..1141579 1 NC_008011.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 1141579 dnaK 4060380 dnaK Lawsonia intracellularis PHE/MN1-00 molecular chaperone DnaK YP_595287.1 1139678 D 363253 CDS YP_595288.1 94987355 4059386 complement(1141712..1143127) 1 NC_008011.1 catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 1143127 aspA 4059386 aspA Lawsonia intracellularis PHE/MN1-00 aspartate ammonia-lyase YP_595288.1 1141712 R 363253 CDS YP_595289.1 94987356 4060444 complement(1143320..1144207) 1 NC_008011.1 D-alanyl-D-alanine carboxypeptidase 1144207 dacC 4060444 dacC Lawsonia intracellularis PHE/MN1-00 D-alanyl-D-alanine carboxypeptidase YP_595289.1 1143320 R 363253 CDS YP_595290.1 94987357 4059649 1144573..1145496 1 NC_008011.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 1145496 livE 4059649 livE Lawsonia intracellularis PHE/MN1-00 branched-chain amino acid aminotransferase YP_595290.1 1144573 D 363253 CDS YP_595291.1 94987358 4060382 1145527..1147251 1 NC_008011.1 DNA polymerase III, gamma/tau subunits 1147251 dnaX 4060382 dnaX Lawsonia intracellularis PHE/MN1-00 DNA polymerase III, gamma/tau subunits YP_595291.1 1145527 D 363253 CDS YP_595292.1 94987359 4059435 1147270..1147581 1 NC_008011.1 hypothetical protein 1147581 4059435 LI0917 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595292.1 1147270 D 363253 CDS YP_595293.1 94987360 4059944 1147646..1148257 1 NC_008011.1 recombinational DNA repair protein 1148257 recR 4059944 recR Lawsonia intracellularis PHE/MN1-00 recombinational DNA repair protein YP_595293.1 1147646 D 363253 CDS YP_595294.1 94987361 4059436 complement(1148418..1149008) 1 NC_008011.1 helicase family protein 1149008 4059436 LI0919 Lawsonia intracellularis PHE/MN1-00 helicase family protein YP_595294.1 1148418 R 363253 CDS YP_595295.1 94987362 4059437 complement(1149173..1150072) 1 NC_008011.1 membrane proteins related to metalloendopeptidases 1150072 4059437 LI0920 Lawsonia intracellularis PHE/MN1-00 membrane proteins related to metalloendopeptidases YP_595295.1 1149173 R 363253 CDS YP_595296.1 94987363 4059992 1150886..1152172 1 NC_008011.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 1152172 purD 4059992 purD Lawsonia intracellularis PHE/MN1-00 phosphoribosylamine--glycine ligase YP_595296.1 1150886 D 363253 CDS YP_595297.1 94987364 4059957 1152159..1152674 1 NC_008011.1 phosphoribosylcarboxyaminoimidazole (NCAIR) mutase 1152674 purK 4059957 purK Lawsonia intracellularis PHE/MN1-00 phosphoribosylcarboxyaminoimidazole (NCAIR) mutase YP_595297.1 1152159 D 363253 CDS YP_595298.1 94987365 4059682 1152735..1153367 1 NC_008011.1 Signal peptidase I 1153367 lepB 4059682 lepB Lawsonia intracellularis PHE/MN1-00 Signal peptidase I YP_595298.1 1152735 D 363253 CDS YP_595299.1 94987366 4059972 complement(1153381..1153701) 1 NC_008011.1 membrane transporters of cations and cationic drugs 1153701 qacE 4059972 qacE Lawsonia intracellularis PHE/MN1-00 membrane transporters of cations and cationic drugs YP_595299.1 1153381 R 363253 CDS YP_595300.1 94987367 4059973 complement(1153732..1154109) 1 NC_008011.1 membrane transporters of cations and cationic drugs 1154109 qacE 4059973 qacE Lawsonia intracellularis PHE/MN1-00 membrane transporters of cations and cationic drugs YP_595300.1 1153732 R 363253 CDS YP_595301.1 94987368 4060148 complement(1154151..1156142) 1 NC_008011.1 hypothetical protein 1156142 mdoB 4060148 mdoB Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595301.1 1154151 R 363253 CDS YP_595302.1 94987369 4060087 complement(1156205..1157719) 1 NC_008011.1 uncharacterized membrane protein, virulence factor 1157719 mviN 4060087 mviN Lawsonia intracellularis PHE/MN1-00 uncharacterized membrane protein, virulence factor YP_595302.1 1156205 R 363253 CDS YP_595303.1 94987370 4059814 1157845..1158960 1 NC_008011.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 1158960 tgt 4059814 tgt Lawsonia intracellularis PHE/MN1-00 queuine tRNA-ribosyltransferase YP_595303.1 1157845 D 363253 CDS YP_595304.1 94987371 4059438 complement(1159064..1160209) 1 NC_008011.1 cell wall biosynthesis glycosyltransferase 1160209 4059438 LI0929 Lawsonia intracellularis PHE/MN1-00 cell wall biosynthesis glycosyltransferase YP_595304.1 1159064 R 363253 CDS YP_595305.1 94987372 4059884 complement(1160320..1160706) 1 NC_008011.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 1160706 rplL 4059884 rplL Lawsonia intracellularis PHE/MN1-00 50S ribosomal protein L7/L12 YP_595305.1 1160320 R 363253 CDS YP_595306.1 94987373 4059882 complement(1160754..1161272) 1 NC_008011.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 1161272 rplJ 4059882 rplJ Lawsonia intracellularis PHE/MN1-00 50S ribosomal protein L10 YP_595306.1 1160754 R 363253 CDS YP_595307.1 94987374 4059914 complement(1161433..1162140) 1 NC_008011.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 1162140 rplA 4059914 rplA Lawsonia intracellularis PHE/MN1-00 50S ribosomal protein L1 YP_595307.1 1161433 R 363253 CDS YP_595308.1 94987375 4059883 complement(1162245..1162667) 1 NC_008011.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 1162667 rplK 4059883 rplK Lawsonia intracellularis PHE/MN1-00 50S ribosomal protein L11 YP_595308.1 1162245 R 363253 CDS YP_595309.1 94987376 4060070 complement(1162747..1163331) 1 NC_008011.1 transcription antiterminator 1163331 nusG 4060070 nusG Lawsonia intracellularis PHE/MN1-00 transcription antiterminator YP_595309.1 1162747 R 363253 CDS YP_595310.1 94987377 4059507 complement(1163863..1165056) 1 NC_008011.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 1165056 tufA 4059507 tufA Lawsonia intracellularis PHE/MN1-00 elongation factor Tu YP_595310.1 1163863 R 363253 CDS YP_595311.1 94987378 4059977 complement(1165638..1168367) 1 NC_008011.1 Zn-dependent peptidase 1168367 pqqL 4059977 pqqL Lawsonia intracellularis PHE/MN1-00 Zn-dependent peptidase YP_595311.1 1165638 R 363253 CDS YP_595312.1 94987379 4059816 1168519..1169796 1 NC_008011.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 1169796 thiC 4059816 thiC Lawsonia intracellularis PHE/MN1-00 thiamine biosynthesis protein ThiC YP_595312.1 1168519 D 363253 CDS YP_595313.1 94987380 4059993 complement(1169954..1171351) 1 NC_008011.1 glutamine phosphoribosylpyrophosphate amidotransferase 1171351 purF 4059993 purF Lawsonia intracellularis PHE/MN1-00 glutamine phosphoribosylpyrophosphate amidotransferase YP_595313.1 1169954 R 363253 CDS YP_595314.1 94987381 4060403 complement(1171427..1174657) 1 NC_008011.1 carbamoylphosphate synthase large subunit (split gene in MJ) 1174657 carB 4060403 carB Lawsonia intracellularis PHE/MN1-00 carbamoylphosphate synthase large subunit (split gene in MJ) YP_595314.1 1171427 R 363253 CDS YP_595315.1 94987382 4059536 1174801..1175283 1 NC_008011.1 ADP-ribose pyrophosphatase 1175283 yqiE 4059536 yqiE Lawsonia intracellularis PHE/MN1-00 ADP-ribose pyrophosphatase YP_595315.1 1174801 D 363253 CDS YP_595316.1 94987383 4060436 1175531..1176382 1 NC_008011.1 Mg2+/Co2+ transporter 1176382 corC 4060436 corC Lawsonia intracellularis PHE/MN1-00 Mg2+/Co2+ transporter YP_595316.1 1175531 D 363253 CDS YP_595317.1 94987384 4059854 1176552..1176923 1 NC_008011.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 1176923 rpsL 4059854 rpsL Lawsonia intracellularis PHE/MN1-00 30S ribosomal protein S12 YP_595317.1 1176552 D 363253 CDS YP_595318.1 94987385 4059850 1177061..1177531 1 NC_008011.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 1177531 rpsG 4059850 rpsG Lawsonia intracellularis PHE/MN1-00 30S ribosomal protein S7 YP_595318.1 1177061 D 363253 CDS YP_595319.1 94987386 4060313 1177547..1179622 1 NC_008011.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 1179622 fusA 4060313 fusA Lawsonia intracellularis PHE/MN1-00 elongation factor G YP_595319.1 1177547 D 363253 CDS YP_595320.1 94987387 4059439 complement(1179650..1180744) 1 NC_008011.1 dienelactone hydrolase 1180744 4059439 LI0945 Lawsonia intracellularis PHE/MN1-00 dienelactone hydrolase YP_595320.1 1179650 R 363253 CDS YP_595321.1 94987388 4060323 1181886..1183754 1 NC_008011.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 1183754 gidA 4060323 gidA Lawsonia intracellularis PHE/MN1-00 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA YP_595321.1 1181886 D 363253 CDS YP_595322.1 94987389 4059440 1184004..1184525 1 NC_008011.1 cell wall-associated hydrolases (invasion-associated proteins) 1184525 4059440 LI0947 Lawsonia intracellularis PHE/MN1-00 cell wall-associated hydrolases (invasion-associated proteins) YP_595322.1 1184004 D 363253 CDS YP_595323.1 94987390 4059441 complement(1184566..1185660) 1 NC_008011.1 glycosyltransferase 1185660 4059441 LI0948 Lawsonia intracellularis PHE/MN1-00 glycosyltransferase YP_595323.1 1184566 R 363253 CDS YP_595324.1 94987391 4059442 complement(1185825..1186151) 1 NC_008011.1 hypothetical protein 1186151 4059442 LI0949 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595324.1 1185825 R 363253 CDS YP_595325.1 94987392 4059443 complement(1186164..1187114) 1 NC_008011.1 branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase 1187114 4059443 LI0950 Lawsonia intracellularis PHE/MN1-00 branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase YP_595325.1 1186164 R 363253 CDS YP_595326.1 94987393 4059384 complement(1187315..1188358) 1 NC_008011.1 aspartate-semialdehyde dehydrogenase 1188358 asd 4059384 asd Lawsonia intracellularis PHE/MN1-00 aspartate-semialdehyde dehydrogenase YP_595326.1 1187315 R 363253 CDS YP_595327.1 94987394 4059444 complement(1189061..1189645) 1 NC_008011.1 hypothetical protein 1189645 4059444 LI0952 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595327.1 1189061 R 363253 CDS YP_595328.1 94987395 4060411 complement(1189772..1190455) 1 NC_008011.1 ABC-type transport system involved in cytochrome c biogenesis, permease component 1190455 ccmC 4060411 ccmC Lawsonia intracellularis PHE/MN1-00 ABC-type transport system involved in cytochrome c biogenesis, permease component YP_595328.1 1189772 R 363253 CDS YP_595329.1 94987396 4059445 complement(1190503..1191180) 1 NC_008011.1 ABC-type transport system involved in cytochrome c biogenesis, permease component 1191180 4059445 LI0954 Lawsonia intracellularis PHE/MN1-00 ABC-type transport system involved in cytochrome c biogenesis, permease component YP_595329.1 1190503 R 363253 CDS YP_595330.1 94987397 4060410 complement(1191225..1191860) 1 NC_008011.1 ABC-type multidrug transport system, ATPase component 1191860 ccmA/ccmB 4060410 ccmA/ccmB Lawsonia intracellularis PHE/MN1-00 ABC-type multidrug transport system, ATPase component YP_595330.1 1191225 R 363253 CDS YP_595331.1 94987398 4060412 complement(1191823..1193829) 1 NC_008011.1 cytochrome c biogenesis factor 1193829 ccmF 4060412 ccmF Lawsonia intracellularis PHE/MN1-00 cytochrome c biogenesis factor YP_595331.1 1191823 R 363253 CDS YP_595332.1 94987399 4060392 complement(1193968..1194384) 1 NC_008011.1 hypothetical protein 1194384 b2503 4060392 b2503 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595332.1 1193968 R 363253 CDS YP_595333.1 94987400 4059531 complement(1194473..1195519) 1 NC_008011.1 hemolysin-like protein 1195519 yhdP 4059531 yhdP Lawsonia intracellularis PHE/MN1-00 hemolysin-like protein YP_595333.1 1194473 R 363253 CDS YP_595334.1 94987401 4059852 1196267..1196584 1 NC_008011.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 1196584 rpsJ 4059852 rpsJ Lawsonia intracellularis PHE/MN1-00 30S ribosomal protein S10 YP_595334.1 1196267 D 363253 CDS YP_595335.1 94987402 4059877 1196606..1197238 1 NC_008011.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 1197238 rplC 4059877 rplC Lawsonia intracellularis PHE/MN1-00 50S ribosomal protein L3 YP_595335.1 1196606 D 363253 CDS YP_595336.1 94987403 4059878 1197254..1197874 1 NC_008011.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 1197874 rplD 4059878 rplD Lawsonia intracellularis PHE/MN1-00 50S ribosomal protein L4 YP_595336.1 1197254 D 363253 CDS YP_595337.1 94987404 4059838 1197889..1198176 1 NC_008011.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 1198176 rplW 4059838 rplW Lawsonia intracellularis PHE/MN1-00 50S ribosomal protein L23 YP_595337.1 1197889 D 363253 CDS YP_595338.1 94987405 4059876 1198179..1199009 1 NC_008011.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 1199009 rplB 4059876 rplB Lawsonia intracellularis PHE/MN1-00 50S ribosomal protein L2 YP_595338.1 1198179 D 363253 CDS YP_595339.1 94987406 4059624 1199018..1199299 1 NC_008011.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 1199299 rpsS 4059624 rpsS Lawsonia intracellularis PHE/MN1-00 30S ribosomal protein S19 YP_595339.1 1199018 D 363253 CDS YP_595340.1 94987407 4059895 1199312..1199650 1 NC_008011.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 1199650 rplV 4059895 rplV Lawsonia intracellularis PHE/MN1-00 50S ribosomal protein L22 YP_595340.1 1199312 D 363253 CDS YP_595341.1 94987408 4059847 1199654..1200295 1 NC_008011.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 1200295 rpsC 4059847 rpsC Lawsonia intracellularis PHE/MN1-00 30S ribosomal protein S3 YP_595341.1 1199654 D 363253 CDS YP_595342.1 94987409 4059888 1200295..1200708 1 NC_008011.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 1200708 rplP 4059888 rplP Lawsonia intracellularis PHE/MN1-00 50S ribosomal protein L16 YP_595342.1 1200295 D 363253 CDS YP_003856778.1 304347695 9711830 1200708..1200893 1 NC_008011.1 50S ribosomal protein L29 1200893 9711830 LI_1205 Lawsonia intracellularis PHE/MN1-00 50S ribosomal protein L29 YP_003856778.1 1200708 D 363253 CDS YP_595343.1 94987410 4059856 1200896..1201162 1 NC_008011.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 1201162 rpsQ 4059856 rpsQ Lawsonia intracellularis PHE/MN1-00 30S ribosomal protein S17 YP_595343.1 1200896 D 363253 CDS YP_595344.1 94987411 4059886 1201178..1201546 1 NC_008011.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 1201546 rplN 4059886 rplN Lawsonia intracellularis PHE/MN1-00 50S ribosomal protein L14 YP_595344.1 1201178 D 363253 CDS YP_595345.1 94987412 4059839 1201555..1201875 1 NC_008011.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 1201875 rplX 4059839 rplX Lawsonia intracellularis PHE/MN1-00 50S ribosomal protein L24 YP_595345.1 1201555 D 363253 CDS YP_595346.1 94987413 4059879 1201885..1202424 1 NC_008011.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 1202424 rplE 4059879 rplE Lawsonia intracellularis PHE/MN1-00 50S ribosomal protein L5 YP_595346.1 1201885 D 363253 CDS YP_595347.1 94987414 4059851 1202656..1203036 1 NC_008011.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 1203036 rpsH 4059851 rpsH Lawsonia intracellularis PHE/MN1-00 30S ribosomal protein S8 YP_595347.1 1202656 D 363253 CDS YP_595348.1 94987415 4059880 1203044..1203589 1 NC_008011.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 1203589 rplF 4059880 rplF Lawsonia intracellularis PHE/MN1-00 50S ribosomal protein L6 YP_595348.1 1203044 D 363253 CDS YP_595349.1 94987416 4059890 1203602..1203964 1 NC_008011.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 1203964 rplR 4059890 rplR Lawsonia intracellularis PHE/MN1-00 50S ribosomal protein L18 YP_595349.1 1203602 D 363253 CDS YP_595350.1 94987417 4059849 1203989..1204480 1 NC_008011.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 1204480 rpsE 4059849 rpsE Lawsonia intracellularis PHE/MN1-00 30S ribosomal protein S5 YP_595350.1 1203989 D 363253 CDS YP_595351.1 94987418 4059887 1204661..1205110 1 NC_008011.1 late assembly protein; 50S ribosomal protein L15 1205110 rplO 4059887 rplO Lawsonia intracellularis PHE/MN1-00 50S ribosomal protein L15 YP_595351.1 1204661 D 363253 CDS YP_595352.1 94987419 4059639 1205122..1206429 1 NC_008011.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 1206429 secY 4059639 secY Lawsonia intracellularis PHE/MN1-00 preprotein translocase subunit SecY YP_595352.1 1205122 D 363253 CDS YP_595353.1 94987420 4060145 1206433..1207203 1 NC_008011.1 methionine aminopeptidase 1207203 map 4060145 map Lawsonia intracellularis PHE/MN1-00 methionine aminopeptidase YP_595353.1 1206433 D 363253 CDS YP_595354.1 94987421 4059855 1207425..1207793 1 NC_008011.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 1207793 rpsM 4059855 rpsM Lawsonia intracellularis PHE/MN1-00 30S ribosomal protein S13 YP_595354.1 1207425 D 363253 CDS YP_595355.1 94987422 4059853 1207850..1208239 1 NC_008011.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 1208239 rpsK 4059853 rpsK Lawsonia intracellularis PHE/MN1-00 30S ribosomal protein S11 YP_595355.1 1207850 D 363253 CDS YP_595356.1 94987423 4059848 1208262..1208888 1 NC_008011.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 1208888 rpsD 4059848 rpsD Lawsonia intracellularis PHE/MN1-00 30S ribosomal protein S4 YP_595356.1 1208262 D 363253 CDS YP_595357.1 94987424 4059841 1208901..1209944 1 NC_008011.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 1209944 rpoA 4059841 rpoA Lawsonia intracellularis PHE/MN1-00 DNA-directed RNA polymerase subunit alpha YP_595357.1 1208901 D 363253 CDS YP_595358.1 94987425 4059889 1209934..1210314 1 NC_008011.1 ribosomal protein L17 1210314 rplQ 4059889 rplQ Lawsonia intracellularis PHE/MN1-00 ribosomal protein L17 YP_595358.1 1209934 D 363253 CDS YP_595359.1 94987426 4059613 1210609..1212024 1 NC_008011.1 phosphomannose isomerase/GDP-mannose pyrophosphorylase 1212024 xanB 4059613 xanB Lawsonia intracellularis PHE/MN1-00 phosphomannose isomerase/GDP-mannose pyrophosphorylase YP_595359.1 1210609 D 363253 CDS YP_595360.1 94987427 4059611 1212317..1213618 1 NC_008011.1 Na+/H+ antiporter 1213618 vc0389 4059611 vc0389 Lawsonia intracellularis PHE/MN1-00 Na+/H+ antiporter YP_595360.1 1212317 D 363253 CDS YP_595361.1 94987428 4059686 1213908..1215167 1 NC_008011.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 1215167 hisS 4059686 hisS Lawsonia intracellularis PHE/MN1-00 histidyl-tRNA synthetase YP_595361.1 1213908 D 363253 CDS YP_595362.1 94987429 4059388 1215195..1216994 1 NC_008011.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1216994 aspS 4059388 aspS Lawsonia intracellularis PHE/MN1-00 aspartyl-tRNA synthetase YP_595362.1 1215195 D 363253 CDS YP_595363.1 94987430 4060383 1217085..1218077 1 NC_008011.1 oligopeptide ABC transporter ATP-binding protein 1218077 dppF 4060383 dppF Lawsonia intracellularis PHE/MN1-00 oligopeptide ABC transporter ATP-binding protein YP_595363.1 1217085 D 363253 CDS YP_595364.1 94987431 4059446 1218216..1218980 1 NC_008011.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 1218980 4059446 LI0989 Lawsonia intracellularis PHE/MN1-00 3-deoxy-manno-octulosonate cytidylyltransferase YP_595364.1 1218216 D 363253 CDS YP_595365.1 94987432 4060402 1218980..1220110 1 NC_008011.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 1220110 carA 4060402 carA Lawsonia intracellularis PHE/MN1-00 carbamoyl phosphate synthase small subunit YP_595365.1 1218980 D 363253 CDS YP_595366.1 94987433 4059447 1220290..1221117 1 NC_008011.1 GluNAc transferase 1221117 4059447 LI0991 Lawsonia intracellularis PHE/MN1-00 GluNAc transferase YP_595366.1 1220290 D 363253 CDS YP_595367.1 94987434 4059448 complement(1221162..1221821) 1 NC_008011.1 hypothetical protein 1221821 4059448 LI0992 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595367.1 1221162 R 363253 CDS YP_595368.1 94987435 4060341 1222274..1223455 1 NC_008011.1 multidrug efflux membrane permease 1223455 acrA 4060341 acrA Lawsonia intracellularis PHE/MN1-00 multidrug efflux membrane permease YP_595368.1 1222274 D 363253 CDS YP_595369.1 94987436 4060342 1223455..1226604 1 NC_008011.1 acriflavin resistance protein D 1226604 acrB 4060342 acrB Lawsonia intracellularis PHE/MN1-00 acriflavin resistance protein D YP_595369.1 1223455 D 363253 CDS YP_595370.1 94987437 4060017 1226608..1227987 1 NC_008011.1 outer membrane efflux protein 1227987 oprM 4060017 oprM Lawsonia intracellularis PHE/MN1-00 outer membrane efflux protein YP_595370.1 1226608 D 363253 CDS YP_595371.1 94987438 4059449 1228358..1228783 1 NC_008011.1 hypothetical protein 1228783 4059449 LI0996 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595371.1 1228358 D 363253 CDS YP_595372.1 94987439 4059990 1228824..1230155 1 NC_008011.1 adenylosuccinate lyase 1230155 purB 4059990 purB Lawsonia intracellularis PHE/MN1-00 adenylosuccinate lyase YP_595372.1 1228824 D 363253 CDS YP_595373.1 94987440 4059968 1230186..1230749 1 NC_008011.1 orotate phosphoribosyltransferase 1230749 pyrE 4059968 pyrE Lawsonia intracellularis PHE/MN1-00 orotate phosphoribosyltransferase YP_595373.1 1230186 D 363253 CDS YP_595374.1 94987441 4059450 1231102..1232007 1 NC_008011.1 hypothetical protein 1232007 4059450 LI0999 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595374.1 1231102 D 363253 CDS YP_595375.1 94987442 4059451 1232004..1232939 1 NC_008011.1 hypothetical protein 1232939 4059451 LI1000 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595375.1 1232004 D 363253 CDS YP_595376.1 94987443 4060053 1233552..1234028 1 NC_008011.1 cytochrome c nitrite reductase small subunit 1234028 napC 4060053 napC Lawsonia intracellularis PHE/MN1-00 cytochrome c nitrite reductase small subunit YP_595376.1 1233552 D 363253 CDS YP_595377.1 94987444 4060064 1234021..1235574 1 NC_008011.1 chain A, cytochrome C nitrite reductase 1235574 nrfA 4060064 nrfA Lawsonia intracellularis PHE/MN1-00 chain A, cytochrome C nitrite reductase YP_595377.1 1234021 D 363253 CDS YP_595378.1 94987445 4060139 complement(1235666..1236898) 1 NC_008011.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase 1236898 lysC 4060139 lysC Lawsonia intracellularis PHE/MN1-00 aspartate kinase YP_595378.1 1235666 R 363253 CDS YP_595379.1 94987446 4059452 complement(1236903..1237505) 1 NC_008011.1 ATPase or kinase 1237505 4059452 LI1004 Lawsonia intracellularis PHE/MN1-00 ATPase or kinase YP_595379.1 1236903 R 363253 CDS YP_595380.1 94987447 4059501 1237651..1238547 1 NC_008011.1 pseudouridine synthase 1238547 truB 4059501 truB Lawsonia intracellularis PHE/MN1-00 pseudouridine synthase YP_595380.1 1237651 D 363253 CDS YP_003856779.1 304347696 9711829 1238578..1238847 1 NC_008011.1 30S ribosomal protein S15 1238847 9711829 LI_1210 Lawsonia intracellularis PHE/MN1-00 30S ribosomal protein S15 YP_003856779.1 1238578 D 363253 CDS YP_595381.1 94987448 4060001 1239053..1241263 1 NC_008011.1 polynucleotide phosphorylase 1241263 pnpA 4060001 pnpA Lawsonia intracellularis PHE/MN1-00 polynucleotide phosphorylase YP_595381.1 1239053 D 363253 CDS YP_595382.1 94987449 4060320 complement(1241379..1242812) 1 NC_008011.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 1242812 gatB 4060320 gatB Lawsonia intracellularis PHE/MN1-00 aspartyl/glutamyl-tRNA amidotransferase subunit B YP_595382.1 1241379 R 363253 CDS YP_595383.1 94987450 4059453 complement(1242831..1243469) 1 NC_008011.1 hypothetical protein 1243469 4059453 LI1008 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595383.1 1242831 R 363253 CDS YP_595384.1 94987451 4059621 complement(1244106..1244963) 1 NC_008011.1 sugar kinase 1244963 yfjB 4059621 yfjB Lawsonia intracellularis PHE/MN1-00 sugar kinase YP_595384.1 1244106 R 363253 CDS YP_595385.1 94987452 4060228 1245221..1245856 1 NC_008011.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 1245856 gmhA 4060228 gmhA Lawsonia intracellularis PHE/MN1-00 phosphoheptose isomerase YP_595385.1 1245221 D 363253 CDS YP_595386.1 94987453 4060262 1246200..1247129 1 NC_008011.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 1247129 hemC 4060262 hemC Lawsonia intracellularis PHE/MN1-00 porphobilinogen deaminase YP_595386.1 1246200 D 363253 CDS YP_595387.1 94987454 4060131 1247217..1249670 1 NC_008011.1 ATP-dependent protease 1249670 lon 4060131 lon Lawsonia intracellularis PHE/MN1-00 ATP-dependent protease YP_595387.1 1247217 D 363253 CDS YP_595388.1 94987455 4060054 complement(1249691..1250893) 1 NC_008011.1 major facilitator superfamily permease 1250893 nar 4060054 nar Lawsonia intracellularis PHE/MN1-00 major facilitator superfamily permease YP_595388.1 1249691 R 363253 CDS YP_595389.1 94987456 4059454 1251229..1251711 1 NC_008011.1 hypothetical protein 1251711 4059454 LI1014 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595389.1 1251229 D 363253 CDS YP_595390.1 94987457 4060250 1251726..1253258 1 NC_008011.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 1253258 gmpA 4060250 gmpA Lawsonia intracellularis PHE/MN1-00 phosphoglyceromutase YP_595390.1 1251726 D 363253 CDS YP_595391.1 94987458 4059279 complement(1253603..1253965) 1 NC_008011.1 hypothetical protein 1253965 4059279 LI1016 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595391.1 1253603 R 363253 CDS YP_595392.1 94987459 4059280 complement(1253967..1254572) 1 NC_008011.1 hypothetical protein 1254572 4059280 LI1017 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595392.1 1253967 R 363253 CDS YP_595393.1 94987460 4059950 complement(1254631..1256223) 1 NC_008011.1 ADP-heptose:LPS heptosyltransferase 1256223 rfaQ 4059950 rfaQ Lawsonia intracellularis PHE/MN1-00 ADP-heptose:LPS heptosyltransferase YP_595393.1 1254631 R 363253 CDS YP_595394.1 94987461 4060132 complement(1256500..1257321) 1 NC_008011.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 1257321 lpxA 4060132 lpxA Lawsonia intracellularis PHE/MN1-00 UDP-N-acetylglucosamine acyltransferase YP_595394.1 1256500 R 363253 CDS YP_595395.1 94987462 4059307 complement(1257321..1257782) 1 NC_008011.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 1257782 fabZ 4059307 fabZ Lawsonia intracellularis PHE/MN1-00 (3R)-hydroxymyristoyl-ACP dehydratase YP_595395.1 1257321 R 363253 CDS YP_595396.1 94987463 4060135 complement(1257792..1258817) 1 NC_008011.1 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 1258817 lpxD 4060135 lpxD Lawsonia intracellularis PHE/MN1-00 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_595396.1 1257792 R 363253 CDS YP_595397.1 94987464 4059281 complement(1258821..1259381) 1 NC_008011.1 Outer membrane protein 1259381 4059281 LI1022 Lawsonia intracellularis PHE/MN1-00 Outer membrane protein YP_595397.1 1258821 R 363253 CDS YP_595398.1 94987465 4060346 complement(1259526..1261328) 1 NC_008011.1 N-acetylmuramoyl-L-alanine amidase 1261328 amiA 4060346 amiA Lawsonia intracellularis PHE/MN1-00 N-acetylmuramoyl-L-alanine amidase YP_595398.1 1259526 R 363253 CDS YP_595399.1 94987466 4059282 complement(1261471..1264125) 1 NC_008011.1 Outer membrane protein/protective antigen OMA87 1264125 4059282 LI1024 Lawsonia intracellularis PHE/MN1-00 Outer membrane protein/protective antigen OMA87 YP_595399.1 1261471 R 363253 CDS YP_595400.1 94987467 4059660 complement(1264118..1264825) 1 NC_008011.1 ABC-type transport system, involved in lipoprotein release, permease component 1264825 lolD 4059660 lolD Lawsonia intracellularis PHE/MN1-00 ABC-type transport system, involved in lipoprotein release, permease component YP_595400.1 1264118 R 363253 CDS YP_595401.1 94987468 4059659 complement(1264828..1266111) 1 NC_008011.1 ABC-type transport system, involved in lipoprotein release, permease component 1266111 lolC 4059659 lolC Lawsonia intracellularis PHE/MN1-00 ABC-type transport system, involved in lipoprotein release, permease component YP_595401.1 1264828 R 363253 CDS YP_595402.1 94987469 4060140 complement(1266111..1267484) 1 NC_008011.1 lysyl-tRNA synthetase (class II) 1267484 lysU 4060140 lysU Lawsonia intracellularis PHE/MN1-00 lysyl-tRNA synthetase (class II) YP_595402.1 1266111 R 363253 CDS YP_595403.1 94987470 4059283 1268376..1269200 1 NC_008011.1 phosphate-binding protein 1269200 4059283 LI1028 Lawsonia intracellularis PHE/MN1-00 phosphate-binding protein YP_595403.1 1268376 D 363253 CDS YP_595404.1 94987471 4059987 1269253..1270083 1 NC_008011.1 phosphate transporter permease PstC 1270083 pstC 4059987 pstC Lawsonia intracellularis PHE/MN1-00 phosphate transporter permease PstC YP_595404.1 1269253 D 363253 CDS YP_595405.1 94987472 4059985 1270080..1270970 1 NC_008011.1 phosphate ABC transporter, permease 1270970 pstA 4059985 pstA Lawsonia intracellularis PHE/MN1-00 phosphate ABC transporter, permease YP_595405.1 1270080 D 363253 CDS YP_595406.1 94987473 4059986 1270961..1271734 1 NC_008011.1 phosphate ABC transporter ATP-binding protein 1271734 pstB 4059986 pstB Lawsonia intracellularis PHE/MN1-00 phosphate ABC transporter ATP-binding protein YP_595406.1 1270961 D 363253 CDS YP_595407.1 94987474 4059284 complement(1271838..1272293) 1 NC_008011.1 hypothetical protein 1272293 4059284 LI1032 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595407.1 1271838 R 363253 CDS YP_595408.1 94987475 4059285 complement(1272481..1273890) 1 NC_008011.1 hypothetical protein 1273890 4059285 LI1033 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595408.1 1272481 R 363253 CDS YP_595409.1 94987476 4059286 complement(1274250..1275641) 1 NC_008011.1 hypothetical protein 1275641 4059286 LI1034 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595409.1 1274250 R 363253 CDS YP_595410.1 94987477 4059287 complement(1276286..>1277317) 1 NC_008011.1 hypothetical protein >1277317 4059287 LI1035 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595410.1 1276286 R 363253 CDS YP_595411.1 94987478 4059288 complement(1277447..1278403) 1 NC_008011.1 hypothetical protein 1278403 4059288 LI1036 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595411.1 1277447 R 363253 CDS YP_595412.1 94987479 4059289 complement(1278568..1279566) 1 NC_008011.1 hypothetical protein 1279566 4059289 LI1037 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595412.1 1278568 R 363253 CDS YP_595413.1 94987480 4059290 complement(1279875..1280561) 1 NC_008011.1 hypothetical protein 1280561 4059290 LI1038 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595413.1 1279875 R 363253 CDS YP_595414.1 94987481 4059291 complement(1281061..1282206) 1 NC_008011.1 hypothetical protein 1282206 4059291 LI1039 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595414.1 1281061 R 363253 CDS YP_595415.1 94987482 4059292 complement(1282447..1283466) 1 NC_008011.1 hypothetical protein 1283466 4059292 LI1040 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595415.1 1282447 R 363253 CDS YP_595416.1 94987483 4059293 complement(1283628..1284554) 1 NC_008011.1 hypothetical protein 1284554 4059293 LI1041 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595416.1 1283628 R 363253 CDS YP_595417.1 94987484 4059294 complement(1285000..1286004) 1 NC_008011.1 hypothetical protein 1286004 4059294 LI1042 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595417.1 1285000 R 363253 CDS YP_595418.1 94987485 4059688 complement(1286368..1287339) 1 NC_008011.1 lactate dehydrogenase and related dehydrogenases 1287339 hprA 4059688 hprA Lawsonia intracellularis PHE/MN1-00 lactate dehydrogenase and related dehydrogenases YP_595418.1 1286368 R 363253 CDS YP_595419.1 94987486 4059295 complement(1287421..1288035) 1 NC_008011.1 hypothetical protein 1288035 4059295 LI1044 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595419.1 1287421 R 363253 CDS YP_595420.1 94987487 4059976 complement(1288038..1288997) 1 NC_008011.1 paraquat-inducible protein B 1288997 pqiB 4059976 pqiB Lawsonia intracellularis PHE/MN1-00 paraquat-inducible protein B YP_595420.1 1288038 R 363253 CDS YP_595421.1 94987488 4059296 complement(1288994..1289782) 1 NC_008011.1 ABC-type transport system involved in resistance to organic solvents, ATPase component 1289782 4059296 LI1046 Lawsonia intracellularis PHE/MN1-00 ABC-type transport system involved in resistance to organic solvents, ATPase component YP_595421.1 1288994 R 363253 CDS YP_595422.1 94987489 4059506 complement(1289790..1290950) 1 NC_008011.1 ABC-type transport system involved in resistance to organic solvents, permease component 1290950 ttg2B 4059506 ttg2B Lawsonia intracellularis PHE/MN1-00 ABC-type transport system involved in resistance to organic solvents, permease component YP_595422.1 1289790 R 363253 CDS YP_595423.1 94987490 4060254 complement(1291103..1291672) 1 NC_008011.1 molecular chaperone GrpE (heat shock protein) 1291672 grpE 4060254 grpE Lawsonia intracellularis PHE/MN1-00 molecular chaperone GrpE (heat shock protein) YP_595423.1 1291103 R 363253 CDS YP_595424.1 94987491 4059297 1292388..1293122 1 NC_008011.1 hypothetical protein 1293122 4059297 LI1049 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595424.1 1292388 D 363253 CDS YP_595425.1 94987492 4060446 1293526..1294392 1 NC_008011.1 metal-dependent phosphoesterase 1294392 4060446 LI1050 Lawsonia intracellularis PHE/MN1-00 metal-dependent phosphoesterase YP_595425.1 1293526 D 363253 CDS YP_595426.1 94987493 4059667 1294652..1297465 1 NC_008011.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 1297465 ileS 4059667 ileS Lawsonia intracellularis PHE/MN1-00 isoleucyl-tRNA synthetase YP_595426.1 1294652 D 363253 CDS YP_595427.1 94987494 4060137 1297490..1297984 1 NC_008011.1 lipoprotein signal peptidase 1297984 lsp 4060137 lsp Lawsonia intracellularis PHE/MN1-00 lipoprotein signal peptidase YP_595427.1 1297490 D 363253 CDS YP_595428.1 94987495 4060447 1298127..1299044 1 NC_008011.1 hypothetical protein 1299044 4060447 LI1053 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595428.1 1298127 D 363253 CDS YP_595429.1 94987496 4060424 1299149..1299931 1 NC_008011.1 chemotaxis protein 1299931 cheZ 4060424 cheZ Lawsonia intracellularis PHE/MN1-00 chemotaxis protein YP_595429.1 1299149 D 363253 CDS YP_595430.1 94987497 4060133 1300313..1301428 1 NC_008011.1 Lipid A disaccharide synthetase 1301428 lpxB 4060133 lpxB Lawsonia intracellularis PHE/MN1-00 Lipid A disaccharide synthetase YP_595430.1 1300313 D 363253 CDS YP_595431.1 94987498 4060448 1301682..1302152 1 NC_008011.1 hypothetical protein 1302152 4060448 LI1056 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595431.1 1301682 D 363253 CDS YP_595432.1 94987499 4059392 1302188..1302889 1 NC_008011.1 F0F1-type ATP synthase, subunit a 1302889 atpA 4059392 atpA Lawsonia intracellularis PHE/MN1-00 F0F1-type ATP synthase, subunit a YP_595432.1 1302188 D 363253 CDS YP_595433.1 94987500 4060388 1302949..1303296 1 NC_008011.1 F0F1-type ATP synthase, subunit c 1303296 atpC 4060388 atpC Lawsonia intracellularis PHE/MN1-00 F0F1-type ATP synthase, subunit c YP_595433.1 1302949 D 363253 CDS YP_595434.1 94987501 4060449 1303342..1303977 1 NC_008011.1 modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor Rex 1303977 4060449 LI1059 Lawsonia intracellularis PHE/MN1-00 redox-sensing transcriptional repressor Rex YP_595434.1 1303342 D 363253 CDS YP_595435.1 94987502 4060450 1304124..1304564 1 NC_008011.1 flagellar biosynthesis chaperone 1304564 4060450 LI1060 Lawsonia intracellularis PHE/MN1-00 flagellar biosynthesis chaperone YP_595435.1 1304124 D 363253 CDS YP_595436.1 94987503 4060451 1304581..1305333 1 NC_008011.1 hypothetical protein 1305333 4060451 LI1061 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595436.1 1304581 D 363253 CDS YP_595437.1 94987504 4059500 1305357..1306130 1 NC_008011.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 1306130 truA 4059500 truA Lawsonia intracellularis PHE/MN1-00 tRNA pseudouridine synthase A YP_595437.1 1305357 D 363253 CDS YP_595438.1 94987505 4060452 1306382..1306804 1 NC_008011.1 hypothetical protein 1306804 4060452 LI1063 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595438.1 1306382 D 363253 CDS YP_595439.1 94987506 4059310 1307072..1307548 1 NC_008011.1 Fe-S-cluster-containing hydrogenase components 1 1307548 fdhF 4059310 fdhF Lawsonia intracellularis PHE/MN1-00 Fe-S-cluster-containing hydrogenase components 1 YP_595439.1 1307072 D 363253 CDS YP_595440.1 94987507 4059953 complement(1307621..1308496) 1 NC_008011.1 dTDP-4-dehydrorhamnose reductase 1308496 rfbD 4059953 rfbD Lawsonia intracellularis PHE/MN1-00 dTDP-4-dehydrorhamnose reductase YP_595440.1 1307621 R 363253 CDS YP_595441.1 94987508 4059952 complement(1308493..1309512) 1 NC_008011.1 dTDP-D-glucose 4,6-dehydratase 1309512 rfbB 4059952 rfbB Lawsonia intracellularis PHE/MN1-00 dTDP-D-glucose 4,6-dehydratase YP_595441.1 1308493 R 363253 CDS YP_595442.1 94987509 4060453 1309801..1310592 1 NC_008011.1 cobalamin biosynthesis protein CbiK, Co2+ chelatase 1310592 4060453 LI1067 Lawsonia intracellularis PHE/MN1-00 cobalamin biosynthesis protein CbiK, Co2+ chelatase YP_595442.1 1309801 D 363253 CDS YP_595443.1 94987510 4060454 1310656..1311624 1 NC_008011.1 hypothetical protein 1311624 4060454 LI1068 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595443.1 1310656 D 363253 CDS YP_595444.1 94987511 4059910 1312240..1312479 1 NC_008011.1 RNase P protein component 1312479 rnpA 4059910 rnpA Lawsonia intracellularis PHE/MN1-00 RNase P protein component YP_595444.1 1312240 D 363253 CDS YP_595445.1 94987512 4059533 1312833..1314431 1 NC_008011.1 preprotein translocase subunit YidC 1314431 yidC 4059533 yidC Lawsonia intracellularis PHE/MN1-00 preprotein translocase subunit YidC YP_595445.1 1312833 D 363253 CDS YP_595446.1 94987513 4059672 1314455..1315468 1 NC_008011.1 RNA-binding protein 1315468 jag 4059672 jag Lawsonia intracellularis PHE/MN1-00 RNA-binding protein YP_595446.1 1314455 D 363253 CDS YP_595447.1 94987514 4059815 1315534..1316913 1 NC_008011.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 1316913 trmE 4059815 trmE Lawsonia intracellularis PHE/MN1-00 tRNA modification GTPase TrmE YP_595447.1 1315534 D 363253 CDS YP_595448.1 94987515 4059907 1316917..1317513 1 NC_008011.1 ribonuclease D 1317513 rncS 4059907 rncS Lawsonia intracellularis PHE/MN1-00 ribonuclease D YP_595448.1 1316917 D 363253 CDS YP_595449.1 94987516 4060455 1317595..1320534 1 NC_008011.1 endonuclease 1320534 4060455 LI1074 Lawsonia intracellularis PHE/MN1-00 endonuclease YP_595449.1 1317595 D 363253 CDS YP_595450.1 94987517 4060055 1320591..1321721 1 NC_008011.1 dioxygenases related to 2-nitropropane dioxygenase 1321721 ncd2 4060055 ncd2 Lawsonia intracellularis PHE/MN1-00 dioxygenases related to 2-nitropropane dioxygenase YP_595450.1 1320591 D 363253 CDS YP_595451.1 94987518 4060326 complement(1321808..1322791) 1 NC_008011.1 glucokinase 1322791 glk 4060326 glk Lawsonia intracellularis PHE/MN1-00 glucokinase YP_595451.1 1321808 R 363253 CDS YP_595452.1 94987519 4060456 complement(1322933..1323712) 1 NC_008011.1 hypothetical protein 1323712 4060456 LI1077 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595452.1 1322933 R 363253 CDS YP_595453.1 94987520 4059699 1324889..1326631 1 NC_008011.1 Signal transduction histidine kinase 1326631 HydH 4059699 HydH Lawsonia intracellularis PHE/MN1-00 Signal transduction histidine kinase YP_595453.1 1324889 D 363253 CDS YP_595454.1 94987521 4059698 1326651..1328066 1 NC_008011.1 response regulator 1328066 hydG 4059698 hydG Lawsonia intracellularis PHE/MN1-00 response regulator YP_595454.1 1326651 D 363253 CDS YP_595455.1 94987522 4060457 1328199..1328615 1 NC_008011.1 hypothetical protein 1328615 4060457 LI1080 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595455.1 1328199 D 363253 CDS YP_595456.1 94987523 4060016 complement(1328645..1329628) 1 NC_008011.1 oligopeptide ABC transporter 1329628 oppD 4060016 oppD Lawsonia intracellularis PHE/MN1-00 oligopeptide ABC transporter YP_595456.1 1328645 R 363253 CDS YP_595457.1 94987524 4059311 1330153..1330491 1 NC_008011.1 Fe2+ transport system protein A 1330491 feoA 4059311 feoA Lawsonia intracellularis PHE/MN1-00 Fe2+ transport system protein A YP_595457.1 1330153 D 363253 CDS YP_595458.1 94987525 4059312 1330619..1332820 1 NC_008011.1 Fe2+ transport system protein B 1332820 feoB 4059312 feoB Lawsonia intracellularis PHE/MN1-00 Fe2+ transport system protein B YP_595458.1 1330619 D 363253 CDS YP_595459.1 94987526 4060458 complement(1332824..1334038) 1 NC_008011.1 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C 1334038 glpC 4060458 glpC Lawsonia intracellularis PHE/MN1-00 sn-glycerol-3-phosphate dehydrogenase subunit C YP_595459.1 1332824 R 363253 CDS YP_595460.1 94987527 4060459 complement(1334050..1335303) 1 NC_008011.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B 1335303 4060459 LI1085 Lawsonia intracellularis PHE/MN1-00 anaerobic glycerol-3-phosphate dehydrogenase subunit B YP_595460.1 1334050 R 363253 CDS YP_595461.1 94987528 4060219 complement(1335296..1336924) 1 NC_008011.1 anaerobic glycerol-3-phosphate dehydrogenase subunit A 1336924 glpA 4060219 glpA Lawsonia intracellularis PHE/MN1-00 anaerobic glycerol-3-phosphate dehydrogenase subunit A YP_595461.1 1335296 R 363253 CDS YP_595462.1 94987529 4060460 complement(1337223..1337819) 1 NC_008011.1 hypothetical protein 1337819 4060460 LI1087 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595462.1 1337223 R 363253 CDS YP_595463.1 94987530 4060461 complement(1337816..1338124) 1 NC_008011.1 hypothetical protein 1338124 4060461 LI1088 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595463.1 1337816 R 363253 CDS YP_595464.1 94987531 4060462 1338433..1339086 1 NC_008011.1 methyltransferase 1339086 4060462 LI1089 Lawsonia intracellularis PHE/MN1-00 methyltransferase YP_595464.1 1338433 D 363253 CDS YP_595465.1 94987532 4060463 1339149..1339568 1 NC_008011.1 transcription regulator 1339568 4060463 LI1090 Lawsonia intracellularis PHE/MN1-00 transcription regulator YP_595465.1 1339149 D 363253 CDS YP_595466.1 94987533 4060464 1339592..1340368 1 NC_008011.1 similar protein in Methanocaldococcus converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate as the first step in methanopterin biosynthesis; GTP cyclohydrolase 1340368 4060464 LI1091 Lawsonia intracellularis PHE/MN1-00 GTP cyclohydrolase YP_595466.1 1339592 D 363253 CDS YP_595467.1 94987534 4060465 1340557..1341606 1 NC_008011.1 response regulator 1341606 4060465 LI1092 Lawsonia intracellularis PHE/MN1-00 response regulator YP_595467.1 1340557 D 363253 CDS YP_595468.1 94987535 4060349 1341663..1344893 1 NC_008011.1 Outer membrane protein and related peptidoglycan-associated (lipo)proteins 1344893 4060349 LI1093 Lawsonia intracellularis PHE/MN1-00 Outer membrane protein and related peptidoglycan-associated (lipo)proteins YP_595468.1 1341663 D 363253 CDS YP_595469.1 94987536 4060350 complement(1344921..1345964) 1 NC_008011.1 HD-GYP domain-containing protein 1345964 4060350 LI1094 Lawsonia intracellularis PHE/MN1-00 HD-GYP domain-containing protein YP_595469.1 1344921 R 363253 CDS YP_595470.1 94987537 4059963 complement(1345968..1347383) 1 NC_008011.1 pyruvate kinase 1347383 pykF 4059963 pykF Lawsonia intracellularis PHE/MN1-00 pyruvate kinase YP_595470.1 1345968 R 363253 CDS YP_595471.1 94987538 4060128 1347589..1348038 1 NC_008011.1 MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 1348038 mraZ 4060128 mraZ Lawsonia intracellularis PHE/MN1-00 cell division protein MraZ YP_595471.1 1347589 D 363253 CDS YP_595472.1 94987539 4060351 1348109..1349047 1 NC_008011.1 S-adenosyl-methyltransferase MraW 1349047 mraW 4060351 mraW Lawsonia intracellularis PHE/MN1-00 S-adenosyl-methyltransferase MraW YP_595472.1 1348109 D 363253 CDS YP_595473.1 94987540 4059756 1349553..1351634 1 NC_008011.1 cell division protein FtsI/penicillin-binding protein 2 1351634 ftsI 4059756 ftsI Lawsonia intracellularis PHE/MN1-00 cell division protein FtsI/penicillin-binding protein 2 YP_595473.1 1349553 D 363253 CDS YP_595474.1 94987541 4060077 1351636..1353084 1 NC_008011.1 UDP-N-acetylmuramyl tripeptide synthase 1353084 murE 4060077 murE Lawsonia intracellularis PHE/MN1-00 UDP-N-acetylmuramyl tripeptide synthase YP_595474.1 1351636 D 363253 CDS YP_595475.1 94987542 4060078 1353075..1354469 1 NC_008011.1 UDP-N-acetylmuramyl pentapeptide synthase 1354469 murF 4060078 murF Lawsonia intracellularis PHE/MN1-00 UDP-N-acetylmuramyl pentapeptide synthase YP_595475.1 1353075 D 363253 CDS YP_595476.1 94987543 4060127 1354469..1355545 1 NC_008011.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 1355545 mraY 4060127 mraY Lawsonia intracellularis PHE/MN1-00 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_595476.1 1354469 D 363253 CDS YP_595477.1 94987544 4060076 1355559..1356881 1 NC_008011.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase 1356881 murD 4060076 murD Lawsonia intracellularis PHE/MN1-00 UDP-N-acetylmuramoylalanine-D-glutamate ligase YP_595477.1 1355559 D 363253 CDS YP_595478.1 94987545 4059807 1356868..1358016 1 NC_008011.1 cell division membrane protein 1358016 spoVE 4059807 spoVE Lawsonia intracellularis PHE/MN1-00 cell division membrane protein YP_595478.1 1356868 D 363253 CDS YP_595479.1 94987546 4060079 1358021..1359112 1 NC_008011.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; UDPdiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 1359112 murG 4060079 murG Lawsonia intracellularis PHE/MN1-00 UDPdiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase YP_595479.1 1358021 D 363253 CDS YP_595480.1 94987547 4060075 1359109..1360470 1 NC_008011.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 1360470 murC 4060075 murC Lawsonia intracellularis PHE/MN1-00 UDP-N-acetylmuramate--L-alanine ligase YP_595480.1 1359109 D 363253 CDS YP_595481.1 94987548 4060352 1360502..1361392 1 NC_008011.1 UDP-N-acetylmuramate dehydrogenase 1361392 4060352 LI1106 Lawsonia intracellularis PHE/MN1-00 UDP-N-acetylmuramate dehydrogenase YP_595481.1 1360502 D 363253 CDS YP_595482.1 94987549 4059758 1361386..1362213 1 NC_008011.1 cell division septal protein 1362213 ftsQ 4059758 ftsQ Lawsonia intracellularis PHE/MN1-00 cell division septal protein YP_595482.1 1361386 D 363253 CDS YP_595483.1 94987550 4059754 1362407..1363639 1 NC_008011.1 cell division protein FtsA 1363639 ftsA 4059754 ftsA Lawsonia intracellularis PHE/MN1-00 cell division protein FtsA YP_595483.1 1362407 D 363253 CDS YP_595484.1 94987551 4059759 1363691..1365073 1 NC_008011.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 1365073 ftsZ 4059759 ftsZ Lawsonia intracellularis PHE/MN1-00 cell division protein FtsZ YP_595484.1 1363691 D 363253 CDS YP_595485.1 94987552 4060353 1365182..1365661 1 NC_008011.1 hypothetical protein 1365661 4060353 LI1110 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595485.1 1365182 D 363253 CDS YP_595486.1 94987553 4060354 complement(1365658..1366440) 1 NC_008011.1 amidophosphoribosyltransferase 1366440 4060354 LI1111 Lawsonia intracellularis PHE/MN1-00 amidophosphoribosyltransferase YP_595486.1 1365658 R 363253 CDS YP_595487.1 94987554 4060355 complement(1366446..1367042) 1 NC_008011.1 multimeric flavodoxin WrbA 1367042 4060355 LI1112 Lawsonia intracellularis PHE/MN1-00 multimeric flavodoxin WrbA YP_595487.1 1366446 R 363253 CDS YP_595488.1 94987555 4059379 complement(1367118..1368020) 1 NC_008011.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; ornithine carbamoyltransferase 1368020 argF 4059379 argF Lawsonia intracellularis PHE/MN1-00 ornithine carbamoyltransferase YP_595488.1 1367118 R 363253 CDS YP_595489.1 94987556 4060356 complement(1368164..1370053) 1 NC_008011.1 parvulin-like peptidyl-prolyl isomerase 1370053 4060356 LI1114 Lawsonia intracellularis PHE/MN1-00 parvulin-like peptidyl-prolyl isomerase YP_595489.1 1368164 R 363253 CDS YP_595490.1 94987557 4059313 complement(1370349..1371827) 1 NC_008011.1 response regulator 1371827 flbD 4059313 flbD Lawsonia intracellularis PHE/MN1-00 response regulator YP_595490.1 1370349 R 363253 CDS YP_595491.1 94987558 4059980 1372257..1373870 1 NC_008011.1 catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase 1373870 priS 4059980 priS Lawsonia intracellularis PHE/MN1-00 hydroxylamine reductase YP_595491.1 1372257 D 363253 CDS YP_595492.1 94987559 4060419 1374180..1375139 1 NC_008011.1 chemotaxis signal transduction protein 1375139 cheV 4060419 cheV Lawsonia intracellularis PHE/MN1-00 chemotaxis signal transduction protein YP_595492.1 1374180 D 363253 CDS YP_595493.1 94987560 4060357 1375188..1375997 1 NC_008011.1 hypothetical protein 1375997 4060357 LI1118 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595493.1 1375188 D 363253 CDS YP_595494.1 94987561 4060319 complement(1376132..1377148) 1 NC_008011.1 glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase 1377148 gapB 4060319 gapB Lawsonia intracellularis PHE/MN1-00 glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase YP_595494.1 1376132 R 363253 CDS YP_595495.1 94987562 4059981 complement(1377471..1378307) 1 NC_008011.1 pyrroline-5-carboxylate reductase 1378307 proC 4059981 proC Lawsonia intracellularis PHE/MN1-00 pyrroline-5-carboxylate reductase YP_595495.1 1377471 R 363253 CDS YP_595496.1 94987563 4060056 complement(1378307..1378723) 1 NC_008011.1 nucleoside-diphosphate kinase 1378723 ndk 4060056 ndk Lawsonia intracellularis PHE/MN1-00 nucleoside-diphosphate kinase YP_595496.1 1378307 R 363253 CDS YP_595497.1 94987564 4060358 complement(1378753..1380090) 1 NC_008011.1 hypothetical protein 1380090 4060358 LI1122 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595497.1 1378753 R 363253 CDS YP_595498.1 94987565 4059978 complement(1380396..1381724) 1 NC_008011.1 periplasmic protease 1381724 prc 4059978 prc Lawsonia intracellularis PHE/MN1-00 periplasmic protease YP_595498.1 1380396 R 363253 CDS YP_595499.1 94987566 4060066 complement(1381792..1382472) 1 NC_008011.1 endonuclease III 1382472 nth 4060066 nth Lawsonia intracellularis PHE/MN1-00 endonuclease III YP_595499.1 1381792 R 363253 CDS YP_595500.1 94987567 4060434 complement(1382916..1385270) 1 NC_008011.1 copper-translocating P-type ATPase 1385270 copA 4060434 copA Lawsonia intracellularis PHE/MN1-00 copper-translocating P-type ATPase YP_595500.1 1382916 R 363253 CDS YP_595501.1 94987568 4060359 1385472..1385933 1 NC_008011.1 RNA methyltransferase 1385933 4060359 LI1126 Lawsonia intracellularis PHE/MN1-00 RNA methyltransferase YP_595501.1 1385472 D 363253 CDS YP_595502.1 94987569 4060360 1385991..1387358 1 NC_008011.1 Na+-driven multidrug efflux pump 1387358 4060360 LI1127 Lawsonia intracellularis PHE/MN1-00 Na+-driven multidrug efflux pump YP_595502.1 1385991 D 363253 CDS YP_595503.1 94987570 4060361 1387436..1388335 1 NC_008011.1 hypothetical protein 1388335 4060361 LI1128 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595503.1 1387436 D 363253 CDS YP_595504.1 94987571 4060216 1388490..1389227 1 NC_008011.1 ABC-type polar amino acid transport system, ATPase component 1389227 glnQ 4060216 glnQ Lawsonia intracellularis PHE/MN1-00 ABC-type polar amino acid transport system, ATPase component YP_595504.1 1388490 D 363253 CDS YP_595505.1 94987572 4060362 1389244..1390113 1 NC_008011.1 ribosomal protein L11 methylase 1390113 4060362 LI1130 Lawsonia intracellularis PHE/MN1-00 ribosomal protein L11 methylase YP_595505.1 1389244 D 363253 CDS YP_595506.1 94987573 4059638 complement(1390148..1390486) 1 NC_008011.1 preprotein translocase subunit SecG 1390486 secG 4059638 secG Lawsonia intracellularis PHE/MN1-00 preprotein translocase subunit SecG YP_595506.1 1390148 R 363253 CDS YP_595507.1 94987574 4059831 complement(1390582..1391340) 1 NC_008011.1 triosephosphate isomerase 1391340 tpiA 4059831 tpiA Lawsonia intracellularis PHE/MN1-00 triosephosphate isomerase YP_595507.1 1390582 R 363253 CDS YP_595508.1 94987575 4059901 complement(1391360..1391830) 1 NC_008011.1 acetyltransferase 1391830 rimJ 4059901 rimJ Lawsonia intracellularis PHE/MN1-00 acetyltransferase YP_595508.1 1391360 R 363253 CDS YP_595509.1 94987576 4060363 1391831..1392370 1 NC_008011.1 NTP pyrophosphohydrolases including oxidative damage repair enzymes 1392370 4060363 LI1134 Lawsonia intracellularis PHE/MN1-00 NTP pyrophosphohydrolases including oxidative damage repair enzymes YP_595509.1 1391831 D 363253 CDS YP_595510.1 94987577 4060130 complement(1392420..1393421) 1 NC_008011.1 rod shape-determining protein MreB 1393421 mreB 4060130 mreB Lawsonia intracellularis PHE/MN1-00 rod shape-determining protein MreB YP_595510.1 1392420 R 363253 CDS YP_595511.1 94987578 4060364 complement(1393424..1394458) 1 NC_008011.1 hypothetical protein 1394458 4060364 LI1136 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595511.1 1393424 R 363253 CDS YP_595512.1 94987579 4060416 1394777..1395850 1 NC_008011.1 chemotaxis response regulator 1395850 cheB 4060416 cheB Lawsonia intracellularis PHE/MN1-00 chemotaxis response regulator YP_595512.1 1394777 D 363253 CDS YP_595513.1 94987580 4060365 1395874..1397826 1 NC_008011.1 hypothetical protein 1397826 4060365 LI1138 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595513.1 1395874 D 363253 CDS YP_595514.1 94987581 4060417 1397826..1398701 1 NC_008011.1 methylase of chemotaxis methyl-accepting proteins 1398701 cheR 4060417 cheR Lawsonia intracellularis PHE/MN1-00 methylase of chemotaxis methyl-accepting proteins YP_595514.1 1397826 D 363253 CDS YP_595515.1 94987582 4059805 1398717..1399487 1 NC_008011.1 chromosome partitioning ATPase 1399487 soj 4059805 soj Lawsonia intracellularis PHE/MN1-00 chromosome partitioning ATPase YP_595515.1 1398717 D 363253 CDS YP_595516.1 94987583 4060420 1399691..1400161 1 NC_008011.1 chemotaxis signal transduction protein 1400161 cheW 4060420 cheW Lawsonia intracellularis PHE/MN1-00 chemotaxis signal transduction protein YP_595516.1 1399691 D 363253 CDS YP_595517.1 94987584 4060423 1400172..1400540 1 NC_008011.1 CheY-like receiver 1400540 cheY 4060423 cheY Lawsonia intracellularis PHE/MN1-00 CheY-like receiver YP_595517.1 1400172 D 363253 CDS YP_595518.1 94987585 4060414 1400564..1401208 1 NC_008011.1 chemotaxis protein histidine kinase-like kinase 1401208 cheA_1 4060414 cheA_1 Lawsonia intracellularis PHE/MN1-00 chemotaxis protein histidine kinase-like kinase YP_595518.1 1400564 D 363253 CDS YP_595519.1 94987586 4060415 1401396..1403609 1 NC_008011.1 chemotaxis protein histidine kinase-like kinase 1403609 cheA_2 4060415 cheA_2 Lawsonia intracellularis PHE/MN1-00 chemotaxis protein histidine kinase-like kinase YP_595519.1 1401396 D 363253 CDS YP_595525.1 94987592 4059917 complement(1409027..>1411030) 1 NC_008011.1 regulator >1411030 4059917 LI1150 Lawsonia intracellularis PHE/MN1-00 regulator YP_595525.1 1409027 R 363253 CDS YP_595526.1 94987593 4059918 complement(1411391..1412671) 1 NC_008011.1 transcriptional regulator 1412671 4059918 LI1151 Lawsonia intracellularis PHE/MN1-00 transcriptional regulator YP_595526.1 1411391 R 363253 CDS YP_595527.1 94987594 4059919 complement(1412680..1413048) 1 NC_008011.1 hypothetical protein 1413048 4059919 LI1152 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595527.1 1412680 R 363253 CDS YP_595528.1 94987595 4059920 complement(1413348..>1414544) 1 NC_008011.1 outer protein N >1414544 4059920 LI1153 Lawsonia intracellularis PHE/MN1-00 outer protein N YP_595528.1 1413348 R 363253 CDS YP_595529.1 94987596 4059921 1415356..1416042 1 NC_008011.1 hypothetical protein 1416042 4059921 LI1154 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595529.1 1415356 D 363253 CDS YP_595530.1 94987597 4059922 1416504..1417094 1 NC_008011.1 hypothetical protein 1417094 4059922 LI1155 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595530.1 1416504 D 363253 CDS YP_595531.1 94987598 4059923 1418018..1418524 1 NC_008011.1 hypothetical protein 1418524 4059923 LI1156 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595531.1 1418018 D 363253 CDS YP_595532.1 94987599 4059924 1419132..1419671 1 NC_008011.1 regulatory protein PcrH 1419671 4059924 LI1157 Lawsonia intracellularis PHE/MN1-00 regulatory protein PcrH YP_595532.1 1419132 D 363253 CDS YP_595533.1 94987600 4059925 1419668..1420858 1 NC_008011.1 hypothetical protein 1420858 4059925 LI1158 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595533.1 1419668 D 363253 CDS YP_595534.1 94987601 4059926 1420906..1421703 1 NC_008011.1 hypothetical protein 1421703 4059926 LI1159 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595534.1 1420906 D 363253 CDS YP_595535.1 94987602 4059537 1422992..1424743 1 NC_008011.1 type III secretion protein YscC 1424743 YscC 4059537 YscC Lawsonia intracellularis PHE/MN1-00 type III secretion protein YscC YP_595535.1 1422992 D 363253 CDS YP_595536.1 94987603 4059927 1424743..1426164 1 NC_008011.1 hypothetical protein 1426164 4059927 LI1161 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595536.1 1424743 D 363253 CDS YP_595537.1 94987604 4059928 1426377..1426856 1 NC_008011.1 hypothetical protein 1426856 4059928 LI1162 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595537.1 1426377 D 363253 CDS YP_595538.1 94987605 4059538 1426865..1427701 1 NC_008011.1 type III secretion protein 1427701 YscJ 4059538 YscJ Lawsonia intracellularis PHE/MN1-00 type III secretion protein YP_595538.1 1426865 D 363253 CDS YP_595539.1 94987606 4059539 <1427698..1428378 1 NC_008011.1 type III secretion protein 1428378 YscL 4059539 YscL Lawsonia intracellularis PHE/MN1-00 type III secretion protein YP_595539.1 <1427698 D 363253 CDS YP_595540.1 94987607 4059929 1428350..1429231 1 NC_008011.1 hypothetical protein 1429231 4059929 LI1165 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595540.1 1428350 D 363253 CDS YP_595541.1 94987608 4059930 1429285..1430391 1 NC_008011.1 translocation protein in type III secretion 1430391 4059930 LI1166 Lawsonia intracellularis PHE/MN1-00 translocation protein in type III secretion YP_595541.1 1429285 D 363253 CDS YP_595542.1 94987609 4059931 1430468..1430806 1 NC_008011.1 anti-anti-sigma factor 1430806 4059931 LI1167 Lawsonia intracellularis PHE/MN1-00 anti-anti-sigma factor YP_595542.1 1430468 D 363253 CDS YP_595543.1 94987610 4059626 1430820..1431263 1 NC_008011.1 sigma regulatory factor-histidine kinase 1431263 rsbW 4059626 rsbW Lawsonia intracellularis PHE/MN1-00 sigma regulatory factor-histidine kinase YP_595543.1 1430820 D 363253 CDS YP_595544.1 94987611 4059932 1431313..1432011 1 NC_008011.1 transglycosylase 1432011 4059932 LI1169 Lawsonia intracellularis PHE/MN1-00 transglycosylase YP_595544.1 1431313 D 363253 CDS YP_595545.1 94987612 4060421 1432180..1432665 1 NC_008011.1 chemotaxis signal transduction protein 1432665 cheW 4060421 cheW Lawsonia intracellularis PHE/MN1-00 chemotaxis signal transduction protein YP_595545.1 1432180 D 363253 CDS YP_595546.1 94987613 4059933 complement(1432770..1434458) 1 NC_008011.1 5'-nucleotidase 1434458 4059933 LI1171 Lawsonia intracellularis PHE/MN1-00 5'-nucleotidase YP_595546.1 1432770 R 363253 CDS YP_595547.1 94987614 4059934 1434763..1435746 1 NC_008011.1 hypothetical protein 1435746 4059934 LI1172 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595547.1 1434763 D 363253 CDS YP_595548.1 94987615 4060330 1435746..1438211 1 NC_008011.1 small-conductance mechanosensitive channel 1438211 4060330 LI1173 Lawsonia intracellularis PHE/MN1-00 small-conductance mechanosensitive channel YP_595548.1 1435746 D 363253 CDS YP_595549.1 94987616 4060121 1438532..1439695 1 NC_008011.1 membrane-bound lytic murein transglycosylase C (MltC) 1439695 mltC 4060121 mltC Lawsonia intracellularis PHE/MN1-00 membrane-bound lytic murein transglycosylase C (MltC) YP_595549.1 1438532 D 363253 CDS YP_595550.1 94987617 4060331 1439752..1440264 1 NC_008011.1 hypothetical protein 1440264 4060331 LI1175 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595550.1 1439752 D 363253 CDS YP_595551.1 94987618 4060332 complement(1440333..1441112) 1 NC_008011.1 nitroreductase 1441112 4060332 LI1176 Lawsonia intracellularis PHE/MN1-00 nitroreductase YP_595551.1 1440333 R 363253 CDS YP_595552.1 94987619 4060333 complement(1441109..1443982) 1 NC_008011.1 excinuclease ABC, A subunit 1443982 4060333 LI1177 Lawsonia intracellularis PHE/MN1-00 excinuclease ABC, A subunit YP_595552.1 1441109 R 363253 CDS YP_595553.1 94987620 4060334 complement(1444320..1445030) 1 NC_008011.1 ABC-type cobalt transport system, permease component CbiQ and related transporters 1445030 4060334 LI1178 Lawsonia intracellularis PHE/MN1-00 ABC-type cobalt transport system, permease component CbiQ and related transporters YP_595553.1 1444320 R 363253 CDS YP_595554.1 94987621 4060407 complement(1445008..1445748) 1 NC_008011.1 ABC-type cobalt transport system, ATPase component 1445748 cbiO 4060407 cbiO Lawsonia intracellularis PHE/MN1-00 ABC-type cobalt transport system, ATPase component YP_595554.1 1445008 R 363253 CDS YP_595555.1 94987622 4060400 complement(1445735..1446292) 1 NC_008011.1 hypothetical protein 1446292 bioY 4060400 bioY Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595555.1 1445735 R 363253 CDS YP_595556.1 94987623 4060344 complement(1446330..1448984) 1 NC_008011.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 1448984 alaS 4060344 alaS Lawsonia intracellularis PHE/MN1-00 alanyl-tRNA synthetase YP_595556.1 1446330 R 363253 CDS YP_595557.1 94987624 4059938 complement(1449016..1450083) 1 NC_008011.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 1450083 recA 4059938 recA Lawsonia intracellularis PHE/MN1-00 recombinase A YP_595557.1 1449016 R 363253 CDS YP_595558.1 94987625 4060114 complement(1450184..1452139) 1 NC_008011.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 1452139 metG 4060114 metG Lawsonia intracellularis PHE/MN1-00 methionyl-tRNA synthetase YP_595558.1 1450184 R 363253 CDS YP_595559.1 94987626 4060335 complement(1452273..1453223) 1 NC_008011.1 uncharacterized homolog of PSP1 1453223 4060335 LI1184 Lawsonia intracellularis PHE/MN1-00 uncharacterized homolog of PSP1 YP_595559.1 1452273 R 363253 CDS YP_595560.1 94987627 4060336 complement(1454268..1454885) 1 NC_008011.1 hypothetical protein 1454885 4060336 LI1185 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595560.1 1454268 R 363253 CDS YP_595561.1 94987628 4059629 1455153..1455752 1 NC_008011.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 1455752 ruvA 4059629 ruvA Lawsonia intracellularis PHE/MN1-00 Holliday junction DNA helicase RuvA YP_595561.1 1455153 D 363253 CDS YP_595562.1 94987629 4059630 1455725..1456750 1 NC_008011.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 1456750 ruvB 4059630 ruvB Lawsonia intracellularis PHE/MN1-00 Holliday junction DNA helicase RuvB YP_595562.1 1455725 D 363253 CDS YP_595563.1 94987630 4059824 1456767..1457489 1 NC_008011.1 flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor; FAD-dependent thymidylate synthase 1457489 thyX 4059824 thyX Lawsonia intracellularis PHE/MN1-00 FAD-dependent thymidylate synthase YP_595563.1 1456767 D 363253 CDS YP_595564.1 94972344 4073387 280..1359 1 NC_008012.1 integrase 1359 4073387 LIA001 Lawsonia intracellularis PHE/MN1-00 integrase YP_595564.1 280 D 363253 CDS YP_595565.1 94972345 4073388 complement(1564..1920) 1 NC_008012.1 hypothetical protein 1920 4073388 LIA002 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595565.1 1564 R 363253 CDS YP_595566.1 94972346 4073389 complement(1914..2264) 1 NC_008012.1 hypothetical protein 2264 4073389 LIA003 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595566.1 1914 R 363253 CDS YP_595567.1 94972347 4073390 2560..2889 1 NC_008012.1 hypothetical protein 2889 4073390 LIA004 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595567.1 2560 D 363253 CDS YP_595568.1 94972348 4073391 complement(3335..5296) 1 NC_008012.1 hypothetical protein 5296 4073391 LIA005 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595568.1 3335 R 363253 CDS YP_595569.1 94972349 4073392 complement(5817..6476) 1 NC_008012.1 hypothetical protein 6476 4073392 LIA006 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595569.1 5817 R 363253 CDS YP_595570.1 94972350 4073393 complement(<6841..7245) 1 NC_008012.1 hypothetical protein 7245 4073393 LIA007 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595570.1 <6841 R 363253 CDS YP_595571.1 94972351 4073396 complement(7296..8276) 1 NC_008012.1 putative galactokinase/mevalonate kinase 8276 mvaK1 4073396 mvaK1 Lawsonia intracellularis PHE/MN1-00 putative galactokinase/mevalonate kinase YP_595571.1 7296 R 363253 CDS YP_595572.1 94972352 4073394 complement(8304..9590) 1 NC_008012.1 hypothetical protein 9590 4073394 LIA009 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595572.1 8304 R 363253 CDS YP_595573.1 94972353 4073397 complement(9603..10622) 1 NC_008012.1 Cps2K 10622 4073397 LIA010 Lawsonia intracellularis PHE/MN1-00 Cps2K YP_595573.1 9603 R 363253 CDS YP_595574.1 94972354 4073398 complement(10908..11360) 1 NC_008012.1 S-adenosylmethionine-dependent methyltransferase 11360 4073398 LIA011 Lawsonia intracellularis PHE/MN1-00 S-adenosylmethionine-dependent methyltransferase YP_595574.1 10908 R 363253 CDS YP_595575.1 94972355 4073399 complement(11381..12091) 1 NC_008012.1 hypothetical protein 12091 4073399 LIA012 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595575.1 11381 R 363253 CDS YP_595576.1 94972356 4073400 complement(12124..12882) 1 NC_008012.1 biotin synthesis protein BioC 12882 4073400 LIA013 Lawsonia intracellularis PHE/MN1-00 biotin synthesis protein BioC YP_595576.1 12124 R 363253 CDS YP_595577.1 94972357 4073401 complement(13079..13909) 1 NC_008012.1 trans-aconitate methyltransferase 13909 4073401 LIA014 Lawsonia intracellularis PHE/MN1-00 trans-aconitate methyltransferase YP_595577.1 13079 R 363253 CDS YP_595578.1 94972358 4073402 complement(13950..15080) 1 NC_008012.1 hypothetical protein 15080 4073402 LIA015 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595578.1 13950 R 363253 CDS YP_595579.1 94972359 4073403 complement(15288..16061) 1 NC_008012.1 hypothetical protein 16061 4073403 LIA016 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595579.1 15288 R 363253 CDS YP_595580.1 94972360 4073414 complement(16055..17518) 1 NC_008012.1 Fe-S oxidoreductase 17518 bchE 4073414 bchE Lawsonia intracellularis PHE/MN1-00 Fe-S oxidoreductase YP_595580.1 16055 R 363253 CDS YP_595581.1 94972361 4073404 complement(17553..17906) 1 NC_008012.1 hypothetical protein 17906 4073404 LIA018 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595581.1 17553 R 363253 CDS YP_595582.1 94972362 4073395 complement(17912..18493) 1 NC_008012.1 phosphoheptose isomerase 18493 gmhA 4073395 gmhA Lawsonia intracellularis PHE/MN1-00 phosphoheptose isomerase YP_595582.1 17912 R 363253 CDS YP_595583.1 94972363 4073405 complement(18514..18888) 1 NC_008012.1 hypothetical protein 18888 4073405 LIA020 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595583.1 18514 R 363253 CDS YP_595584.1 94972364 4073406 complement(18943..19275) 1 NC_008012.1 hypothetical protein 19275 4073406 LIA021 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595584.1 18943 R 363253 CDS YP_595585.1 94972365 4073407 complement(19278..19784) 1 NC_008012.1 cell wall biosynthesis glycosyltransferase 19784 4073407 LIA022 Lawsonia intracellularis PHE/MN1-00 cell wall biosynthesis glycosyltransferase YP_595585.1 19278 R 363253 CDS YP_595586.1 94972366 4073415 complement(20042..21061) 1 NC_008012.1 nucleoside-diphosphate-sugar epimerase 21061 galE 4073415 galE Lawsonia intracellularis PHE/MN1-00 nucleoside-diphosphate-sugar epimerase YP_595586.1 20042 R 363253 CDS YP_595587.1 94972367 4073408 complement(21140..21898) 1 NC_008012.1 cell wall biosynthesis glycosyltransferase 21898 4073408 LIA024 Lawsonia intracellularis PHE/MN1-00 cell wall biosynthesis glycosyltransferase YP_595587.1 21140 R 363253 CDS YP_595588.1 94972368 4073409 complement(21988..22320) 1 NC_008012.1 plasmid stabilization system protein 22320 4073409 LIA025 Lawsonia intracellularis PHE/MN1-00 plasmid stabilization system protein YP_595588.1 21988 R 363253 CDS YP_595589.1 94972369 4073410 complement(22310..22588) 1 NC_008012.1 hypothetical protein 22588 4073410 LIA026 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595589.1 22310 R 363253 CDS YP_595590.1 94972370 4073411 complement(23098..24147) 1 NC_008012.1 hypothetical protein 24147 4073411 LIA027 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595590.1 23098 R 363253 CDS YP_595591.1 94972371 4073412 24353..25753 1 NC_008012.1 hypothetical protein 25753 4073412 LIA028 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595591.1 24353 D 363253 CDS YP_595592.1 94972372 4073413 25951..26709 1 NC_008012.1 chromosome-partitioning ATPase 26709 4073413 LIA029 Lawsonia intracellularis PHE/MN1-00 chromosome-partitioning ATPase YP_595592.1 25951 D 363253 CDS YP_595593.1 94972374 4073432 404..691 1 NC_008013.1 hypothetical protein 691 4073432 LIB001 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595593.1 404 D 363253 CDS YP_595594.1 94972375 4073433 complement(2232..2513) 1 NC_008013.1 PbsX family transcriptional regulator 2513 4073433 LIB002 Lawsonia intracellularis PHE/MN1-00 PbsX family transcriptional regulator YP_595594.1 2232 R 363253 CDS YP_595595.1 94972376 4073434 2785..3822 1 NC_008013.1 hypothetical protein 3822 4073434 LIB003 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595595.1 2785 D 363253 CDS YP_595596.1 94972377 4073435 complement(5055..7874) 1 NC_008013.1 Asn/Thr/Ser/Val rich protein 7874 4073435 LIB004 Lawsonia intracellularis PHE/MN1-00 Asn/Thr/Ser/Val rich protein YP_595596.1 5055 R 363253 CDS YP_595597.1 94972378 4073436 complement(8334..9338) 1 NC_008013.1 hypothetical protein 9338 4073436 LIB005 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595597.1 8334 R 363253 CDS YP_595598.1 94972379 4073437 10436..12607 1 NC_008013.1 hypothetical protein 12607 4073437 LIB006 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595598.1 10436 D 363253 CDS YP_595599.1 94972380 4073429 complement(12772..14652) 1 NC_008013.1 putative asparagine synthetase 14652 asnB 4073429 asnB Lawsonia intracellularis PHE/MN1-00 putative asparagine synthetase YP_595599.1 12772 R 363253 CDS YP_595600.1 94972381 4073438 complement(14668..15459) 1 NC_008013.1 hypothetical protein 15459 4073438 LIB008 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595600.1 14668 R 363253 CDS YP_595601.1 94972382 4073439 complement(15453..16469) 1 NC_008013.1 hypothetical protein 16469 4073439 LIB009 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595601.1 15453 R 363253 CDS YP_595602.1 94972383 4073416 complement(16482..17606) 1 NC_008013.1 DegT/DnrJ/EryC1/StrS aminotransferase family protein 17606 4073416 LIB010 Lawsonia intracellularis PHE/MN1-00 DegT/DnrJ/EryC1/StrS aminotransferase family protein YP_595602.1 16482 R 363253 CDS YP_595603.1 94972384 4073431 complement(17627..18526) 1 NC_008013.1 molybdenum cofactor biosynthesis protein 18526 pqqE 4073431 pqqE Lawsonia intracellularis PHE/MN1-00 molybdenum cofactor biosynthesis protein YP_595603.1 17627 R 363253 CDS YP_595604.1 94972385 4073417 complement(18588..19238) 1 NC_008013.1 acetyltransferase 19238 4073417 LIB012 Lawsonia intracellularis PHE/MN1-00 acetyltransferase YP_595604.1 18588 R 363253 CDS YP_595605.1 94972386 4073418 19368..20597 1 NC_008013.1 hypothetical protein 20597 4073418 LIB013 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595605.1 19368 D 363253 CDS YP_595606.1 94972387 4073419 20757..21587 1 NC_008013.1 hypothetical protein 21587 4073419 LIB014 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595606.1 20757 D 363253 CDS YP_595607.1 94972388 4073420 21675..22562 1 NC_008013.1 hypothetical protein 22562 4073420 LIB015 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595607.1 21675 D 363253 CDS YP_595608.1 94972389 4073421 22569..23621 1 NC_008013.1 putative perosamine synthetase 23621 4073421 LIB016 Lawsonia intracellularis PHE/MN1-00 putative perosamine synthetase YP_595608.1 22569 D 363253 CDS YP_595609.1 94972390 4073422 23628..24695 1 NC_008013.1 hypothetical protein 24695 4073422 LIB017 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595609.1 23628 D 363253 CDS YP_595610.1 94972391 4073423 24903..26174 1 NC_008013.1 putative molybdopterin cofactor synthesis protein A 26174 4073423 LIB018 Lawsonia intracellularis PHE/MN1-00 putative molybdopterin cofactor synthesis protein A YP_595610.1 24903 D 363253 CDS YP_595611.1 94972392 4073424 complement(26181..26819) 1 NC_008013.1 hypothetical protein 26819 4073424 LIB019 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595611.1 26181 R 363253 CDS YP_595612.1 94972393 4073425 complement(27548..28714) 1 NC_008013.1 hypothetical protein 28714 4073425 LIB020 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595612.1 27548 R 363253 CDS YP_595613.1 94972394 4073426 31301..31633 1 NC_008013.1 hypothetical protein 31633 4073426 LIB021 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595613.1 31301 D 363253 CDS YP_595614.1 94972395 4073427 33665..36469 1 NC_008013.1 hypothetical protein 36469 4073427 LIB022 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595614.1 33665 D 363253 CDS YP_595615.1 94972396 4073428 36874..38025 1 NC_008013.1 integrase 38025 4073428 LIB023 Lawsonia intracellularis PHE/MN1-00 integrase YP_595615.1 36874 D 363253 CDS YP_595616.1 94972397 4073430 38667..39422 1 NC_008013.1 ATPases involved in chromosome partitioning 39422 parA 4073430 parA Lawsonia intracellularis PHE/MN1-00 ATPases involved in chromosome partitioning YP_595616.1 38667 D 363253 CDS YP_595617.1 94972399 4073459 525..1610 1 NC_008014.1 integrase/recombinase 1610 4073459 LIC001 Lawsonia intracellularis PHE/MN1-00 integrase/recombinase YP_595617.1 525 D 363253 CDS YP_595618.1 94972400 4073460 2657..3580 1 NC_008014.1 hypothetical protein 3580 4073460 LIC002 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595618.1 2657 D 363253 CDS YP_595619.1 94972401 4073511 3754..4872 1 NC_008014.1 putative alpha(1,3)rhamnosyltransferase EpsG 4872 epsG 4073511 epsG Lawsonia intracellularis PHE/MN1-00 putative alpha(1,3)rhamnosyltransferase EpsG YP_595619.1 3754 D 363253 CDS YP_595620.1 94972402 4073519 5115..5657 1 NC_008014.1 dTDP-6-deoxy-D-glucose-3,5-epimerase 5657 rfbC 4073519 rfbC Lawsonia intracellularis PHE/MN1-00 dTDP-6-deoxy-D-glucose-3,5-epimerase YP_595620.1 5115 D 363253 CDS YP_595621.1 94972403 4073461 5841..6644 1 NC_008014.1 ABC transporter 6644 4073461 LIC005 Lawsonia intracellularis PHE/MN1-00 ABC transporter YP_595621.1 5841 D 363253 CDS YP_595622.1 94972404 4073462 6833..7720 1 NC_008014.1 glycosyltransferase 7720 4073462 LIC006 Lawsonia intracellularis PHE/MN1-00 glycosyltransferase YP_595622.1 6833 D 363253 CDS YP_595623.1 94972405 4073463 7836..10205 1 NC_008014.1 hypothetical protein 10205 4073463 LIC007 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595623.1 7836 D 363253 CDS YP_595624.1 94972406 4073464 10465..11196 1 NC_008014.1 methyltransferase 24 11196 4073464 LIC008 Lawsonia intracellularis PHE/MN1-00 methyltransferase 24 YP_595624.1 10465 D 363253 CDS YP_595625.1 94972407 4073465 complement(11293..14562) 1 NC_008014.1 hypothetical protein 14562 4073465 LIC009 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595625.1 11293 R 363253 CDS YP_595626.1 94972408 4073466 complement(14573..15277) 1 NC_008014.1 putative nucleotidyl transferase 15277 4073466 LIC010 Lawsonia intracellularis PHE/MN1-00 putative nucleotidyl transferase YP_595626.1 14573 R 363253 CDS YP_595627.1 94972409 4073515 complement(15277..16257) 1 NC_008014.1 putative galactokinase/mevalonate kinase 16257 mvaK1 4073515 mvaK1 Lawsonia intracellularis PHE/MN1-00 putative galactokinase/mevalonate kinase YP_595627.1 15277 R 363253 CDS YP_595628.1 94972410 4073467 complement(16567..17556) 1 NC_008014.1 putative LmbZ 17556 4073467 LIC012 Lawsonia intracellularis PHE/MN1-00 putative LmbZ YP_595628.1 16567 R 363253 CDS YP_595629.1 94972411 4073468 complement(17553..18434) 1 NC_008014.1 dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) 18434 4073468 LIC013 Lawsonia intracellularis PHE/MN1-00 dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_595629.1 17553 R 363253 CDS YP_595630.1 94972412 4073522 complement(18568..19872) 1 NC_008014.1 UDP-glucose 6-dehydrogenase 19872 ugd 4073522 ugd Lawsonia intracellularis PHE/MN1-00 UDP-glucose 6-dehydrogenase YP_595630.1 18568 R 363253 CDS YP_595631.1 94972413 4073469 complement(19973..20956) 1 NC_008014.1 hypothetical protein 20956 4073469 LIC015 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595631.1 19973 R 363253 CDS YP_595632.1 94972414 4073521 complement(20934..21653) 1 NC_008014.1 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; putative translaldolase 21653 tal 4073521 tal Lawsonia intracellularis PHE/MN1-00 putative translaldolase YP_595632.1 20934 R 363253 CDS YP_595633.1 94972415 4073514 complement(21738..22343) 1 NC_008014.1 histidinol phosphatase and related phosphatases 22343 hisJ 4073514 hisJ Lawsonia intracellularis PHE/MN1-00 histidinol phosphatase and related phosphatases YP_595633.1 21738 R 363253 CDS YP_595634.1 94972416 4073470 complement(22325..22924) 1 NC_008014.1 sugar isomerase family protein 22924 4073470 LIC018 Lawsonia intracellularis PHE/MN1-00 sugar isomerase family protein YP_595634.1 22325 R 363253 CDS YP_595635.1 94972417 4073471 complement(23114..26398) 1 NC_008014.1 hypothetical protein 26398 4073471 LIC019 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595635.1 23114 R 363253 CDS YP_595636.1 94972418 4073472 complement(26718..28187) 1 NC_008014.1 hypothetical protein 28187 4073472 LIC020 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595636.1 26718 R 363253 CDS YP_595637.1 94972419 4073473 complement(28160..28957) 1 NC_008014.1 hypothetical protein 28957 4073473 LIC021 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595637.1 28160 R 363253 CDS YP_595638.1 94972420 4073474 complement(29190..29798) 1 NC_008014.1 hypothetical protein 29798 4073474 LIC022 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595638.1 29190 R 363253 CDS YP_595639.1 94972421 4073512 complement(30157..31122) 1 NC_008014.1 nucleoside-diphosphate-sugar epimerases 31122 galE 4073512 galE Lawsonia intracellularis PHE/MN1-00 nucleoside-diphosphate-sugar epimerases YP_595639.1 30157 R 363253 CDS YP_595640.1 94972422 4073475 complement(31168..31902) 1 NC_008014.1 cell wall biosynthesis glycosyltransferase 31902 4073475 LIC024 Lawsonia intracellularis PHE/MN1-00 cell wall biosynthesis glycosyltransferase YP_595640.1 31168 R 363253 CDS YP_595641.1 94972423 4073476 complement(32380..32919) 1 NC_008014.1 hypothetical protein 32919 4073476 LIC025 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595641.1 32380 R 363253 CDS YP_595642.1 94972424 4073477 complement(32919..33764) 1 NC_008014.1 hypothetical protein 33764 4073477 LIC026 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595642.1 32919 R 363253 CDS YP_595643.1 94972425 4073478 34205..35827 1 NC_008014.1 hypothetical protein 35827 4073478 LIC027 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595643.1 34205 D 363253 CDS YP_595644.1 94972426 4073479 36171..37394 1 NC_008014.1 hypothetical protein 37394 4073479 LIC028 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595644.1 36171 D 363253 CDS YP_595645.1 94972427 4073480 37950..39563 1 NC_008014.1 hypothetical protein 39563 4073480 LIC029 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595645.1 37950 D 363253 CDS YP_595646.1 94972428 4073481 39662..41038 1 NC_008014.1 D-alanine export protein 41038 4073481 LIC030 Lawsonia intracellularis PHE/MN1-00 D-alanine export protein YP_595646.1 39662 D 363253 CDS YP_595647.1 94972429 4073482 41380..41661 1 NC_008014.1 hypothetical protein 41661 4073482 LIC031 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595647.1 41380 D 363253 CDS YP_595648.1 94972430 4073483 complement(41854..42834) 1 NC_008014.1 hypothetical protein 42834 4073483 LIC032 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595648.1 41854 R 363253 CDS YP_595649.1 94972431 4073484 complement(42884..43714) 1 NC_008014.1 hypothetical protein 43714 4073484 LIC033 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595649.1 42884 R 363253 CDS YP_595650.1 94972432 4073485 complement(43711..44217) 1 NC_008014.1 hypothetical protein 44217 4073485 LIC034 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595650.1 43711 R 363253 CDS YP_595651.1 94972433 4073486 complement(44528..45232) 1 NC_008014.1 hypothetical protein 45232 4073486 LIC035 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595651.1 44528 R 363253 CDS YP_595652.1 94972434 4073520 complement(45243..45860) 1 NC_008014.1 putative lytic murein transglycosylase precursor 45860 slt 4073520 slt Lawsonia intracellularis PHE/MN1-00 putative lytic murein transglycosylase precursor YP_595652.1 45243 R 363253 CDS YP_595653.1 94972435 4073487 46792..51615 1 NC_008014.1 signal peptide 51615 4073487 LIC037 Lawsonia intracellularis PHE/MN1-00 signal peptide YP_595653.1 46792 D 363253 CDS YP_595654.1 94972436 4073488 52068..53210 1 NC_008014.1 glycosyltransferase 53210 4073488 LIC038 Lawsonia intracellularis PHE/MN1-00 glycosyltransferase YP_595654.1 52068 D 363253 CDS YP_595655.1 94972437 4073489 complement(53512..55578) 1 NC_008014.1 hypothetical protein 55578 4073489 LIC039 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595655.1 53512 R 363253 CDS YP_595656.1 94972438 4073490 complement(55962..57749) 1 NC_008014.1 hypothetical protein 57749 4073490 LIC040 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595656.1 55962 R 363253 CDS YP_595657.1 94972439 4073491 complement(60308..62806) 1 NC_008014.1 hypothetical protein 62806 4073491 LIC041 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595657.1 60308 R 363253 CDS YP_595658.1 94972440 4073492 complement(63033..65108) 1 NC_008014.1 hypothetical protein 65108 4073492 LIC042 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595658.1 63033 R 363253 CDS YP_595659.1 94972441 4073493 complement(65206..67194) 1 NC_008014.1 hypothetical protein 67194 4073493 LIC043 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595659.1 65206 R 363253 CDS YP_595660.1 94972442 4073494 complement(67446..68417) 1 NC_008014.1 hypothetical protein 68417 4073494 LIC044 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595660.1 67446 R 363253 CDS YP_595661.1 94972443 4073495 complement(68531..69295) 1 NC_008014.1 hypothetical protein 69295 4073495 LIC045 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595661.1 68531 R 363253 CDS YP_595662.1 94972444 4073496 complement(70371..72761) 1 NC_008014.1 hypothetical protein 72761 4073496 LIC046 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595662.1 70371 R 363253 CDS YP_595663.1 94972445 4073497 complement(73376..75901) 1 NC_008014.1 hypothetical protein 75901 4073497 LIC047 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595663.1 73376 R 363253 CDS YP_595664.1 94972446 4073498 complement(77795..79972) 1 NC_008014.1 hypothetical protein 79972 4073498 LIC048 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595664.1 77795 R 363253 CDS YP_595665.1 94972447 4073499 complement(79999..80688) 1 NC_008014.1 hypothetical protein 80688 4073499 LIC049 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595665.1 79999 R 363253 CDS YP_595666.1 94972448 4073500 complement(<81658..>83723) 1 NC_008014.1 hypothetical protein >83723 4073500 LIC050 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595666.1 <81658 R 363253 CDS YP_595667.1 94972449 4073501 complement(84342..86378) 1 NC_008014.1 hypothetical protein 86378 4073501 LIC051 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595667.1 84342 R 363253 CDS YP_595668.1 94972450 4073502 complement(86569..88623) 1 NC_008014.1 hypothetical protein 88623 4073502 LIC052 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595668.1 86569 R 363253 CDS YP_595669.1 94972451 4073503 complement(89091..91199) 1 NC_008014.1 hypothetical protein 91199 4073503 LIC053 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595669.1 89091 R 363253 CDS YP_595670.1 94972452 4073504 complement(91646..93478) 1 NC_008014.1 hypothetical protein 93478 4073504 LIC054 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595670.1 91646 R 363253 CDS YP_595671.1 94972453 4073524 complement(94015..95874) 1 NC_008014.1 hypothetical protein 95874 4073524 LIC055 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595671.1 94015 R 363253 CDS YP_595672.1 94972454 4073525 complement(96167..97960) 1 NC_008014.1 hypothetical protein 97960 4073525 LIC056 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595672.1 96167 R 363253 CDS YP_595673.1 94972455 4073526 complement(99530..101632) 1 NC_008014.1 hypothetical protein 101632 4073526 LIC057 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595673.1 99530 R 363253 CDS YP_595674.1 94972456 4073527 complement(102038..105190) 1 NC_008014.1 hypothetical protein 105190 4073527 LIC058 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595674.1 102038 R 363253 CDS YP_595675.1 94972457 4073528 complement(105648..107375) 1 NC_008014.1 hypothetical protein 107375 4073528 LIC059 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595675.1 105648 R 363253 CDS YP_595676.1 94972458 4073529 complement(108008..109867) 1 NC_008014.1 hypothetical protein 109867 4073529 LIC060 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595676.1 108008 R 363253 CDS YP_595677.1 94972459 4073530 complement(110667..111209) 1 NC_008014.1 hypothetical protein 111209 4073530 LIC061 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595677.1 110667 R 363253 CDS YP_595678.1 94972460 4073531 complement(112870..114228) 1 NC_008014.1 hypothetical protein 114228 4073531 LIC062 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595678.1 112870 R 363253 CDS YP_595679.1 94972461 4073516 114721..115545 1 NC_008014.1 ATPases involved in chromosome partitioning 115545 parA 4073516 parA Lawsonia intracellularis PHE/MN1-00 ATPases involved in chromosome partitioning YP_595679.1 114721 D 363253 CDS YP_595680.1 94972462 4073532 115557..117053 1 NC_008014.1 hypothetical protein 117053 4073532 LIC064 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595680.1 115557 D 363253 CDS YP_595681.1 94972463 4073533 complement(117559..120978) 1 NC_008014.1 hypothetical protein 120978 4073533 LIC065 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595681.1 117559 R 363253 CDS YP_595682.1 94972464 4073534 121983..123122 1 NC_008014.1 hypothetical protein 123122 4073534 LIC066 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595682.1 121983 D 363253 CDS YP_595683.1 94972465 4073535 123218..124081 1 NC_008014.1 hypothetical protein 124081 4073535 LIC067 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595683.1 123218 D 363253 CDS YP_595684.1 94972466 4073536 124084..124533 1 NC_008014.1 hypothetical protein 124533 4073536 LIC068 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595684.1 124084 D 363253 CDS YP_595685.1 94972467 4073537 124556..125200 1 NC_008014.1 hypothetical protein 125200 4073537 LIC069 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595685.1 124556 D 363253 CDS YP_595686.1 94972468 4073538 125278..126693 1 NC_008014.1 phage sheath protein 126693 4073538 LIC070 Lawsonia intracellularis PHE/MN1-00 phage sheath protein YP_595686.1 125278 D 363253 CDS YP_595687.1 94972469 4073539 126956..127345 1 NC_008014.1 hypothetical protein 127345 4073539 LIC071 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595687.1 126956 D 363253 CDS YP_595688.1 94972470 4073540 127347..127670 1 NC_008014.1 hypothetical protein 127670 4073540 LIC072 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595688.1 127347 D 363253 CDS YP_595689.1 94972471 4073541 127923..128792 1 NC_008014.1 hypothetical protein 128792 4073541 LIC073 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595689.1 127923 D 363253 CDS YP_595690.1 94972472 4073542 129105..130370 1 NC_008014.1 hypothetical protein 130370 4073542 LIC074 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595690.1 129105 D 363253 CDS YP_595691.1 94972473 4073543 130491..131522 1 NC_008014.1 putative phage tail protein 131522 4073543 LIC075 Lawsonia intracellularis PHE/MN1-00 putative phage tail protein YP_595691.1 130491 D 363253 CDS YP_595692.1 94972474 4073440 131586..132182 1 NC_008014.1 hypothetical protein 132182 4073440 LIC076 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595692.1 131586 D 363253 CDS YP_595693.1 94972475 4073441 complement(132327..133022) 1 NC_008014.1 hypothetical protein 133022 4073441 LIC077 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595693.1 132327 R 363253 CDS YP_595694.1 94972476 4073442 complement(133350..133736) 1 NC_008014.1 protein synthesis inhibitor, putative 133736 4073442 LIC078 Lawsonia intracellularis PHE/MN1-00 protein synthesis inhibitor, putative YP_595694.1 133350 R 363253 CDS YP_595695.1 94972477 4073443 complement(134013..135005) 1 NC_008014.1 hypothetical protein 135005 4073443 LIC079 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595695.1 134013 R 363253 CDS YP_595696.1 94972478 4073444 complement(135091..136032) 1 NC_008014.1 GDP-L-fucose synthetase-related 136032 4073444 LIC080 Lawsonia intracellularis PHE/MN1-00 GDP-L-fucose synthetase-related YP_595696.1 135091 R 363253 CDS YP_595697.1 94972479 4073518 complement(136395..137753) 1 NC_008014.1 replicative DNA helicase 137753 recQ 4073518 recQ Lawsonia intracellularis PHE/MN1-00 replicative DNA helicase YP_595697.1 136395 R 363253 CDS YP_595698.1 94972480 4073513 138575..139735 1 NC_008014.1 GDP-D-mannose dehydratase 139735 gmd 4073513 gmd Lawsonia intracellularis PHE/MN1-00 GDP-D-mannose dehydratase YP_595698.1 138575 D 363253 CDS YP_595699.1 94972481 4073445 140126..140452 1 NC_008014.1 hypothetical protein 140452 4073445 LIC083 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595699.1 140126 D 363253 CDS YP_595700.1 94972482 4073446 140609..140983 1 NC_008014.1 phage-related membrane protein 140983 4073446 LIC084 Lawsonia intracellularis PHE/MN1-00 phage-related membrane protein YP_595700.1 140609 D 363253 CDS YP_595701.1 94972483 4073447 complement(141084..142049) 1 NC_008014.1 glycosyl transferase 142049 4073447 LIC085 Lawsonia intracellularis PHE/MN1-00 glycosyl transferase YP_595701.1 141084 R 363253 CDS YP_595702.1 94972484 4073448 complement(142046..143107) 1 NC_008014.1 glycosyltransferase 143107 4073448 LIC086 Lawsonia intracellularis PHE/MN1-00 glycosyltransferase YP_595702.1 142046 R 363253 CDS YP_595703.1 94972485 4073449 143397..143747 1 NC_008014.1 hypothetical protein 143747 4073449 LIC087 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595703.1 143397 D 363253 CDS YP_595704.1 94972486 4073450 144107..144823 1 NC_008014.1 hypothetical protein 144823 4073450 LIC088 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595704.1 144107 D 363253 CDS YP_595705.1 94972487 4073451 144828..145394 1 NC_008014.1 hypothetical protein 145394 4073451 LIC089 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595705.1 144828 D 363253 CDS YP_595706.1 94972488 4073452 complement(146282..147724) 1 NC_008014.1 proton/peptide symporter family protein 147724 4073452 LIC090 Lawsonia intracellularis PHE/MN1-00 proton/peptide symporter family protein YP_595706.1 146282 R 363253 CDS YP_595707.1 94972489 4073453 148401..174641 1 NC_008014.1 hypothetical protein 174641 4073453 LIC091 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595707.1 148401 D 363253 CDS YP_595708.1 94972490 4073454 174997..176478 1 NC_008014.1 hypothetical protein 176478 4073454 LIC092 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595708.1 174997 D 363253 CDS YP_595709.1 94972491 4073455 complement(176743..178116) 1 NC_008014.1 UDP-N-acetyl-D-mannosaminuronate dehydrogenase 178116 4073455 LIC093 Lawsonia intracellularis PHE/MN1-00 UDP-N-acetyl-D-mannosaminuronate dehydrogenase YP_595709.1 176743 R 363253 CDS YP_595710.1 94972492 4073456 complement(178467..179024) 1 NC_008014.1 WblC protein 179024 4073456 LIC094 Lawsonia intracellularis PHE/MN1-00 WblC protein YP_595710.1 178467 R 363253 CDS YP_595711.1 94972493 4073457 complement(179021..180190) 1 NC_008014.1 DegT/DnrJ/EryC1/StrS family protein 180190 4073457 LIC095 Lawsonia intracellularis PHE/MN1-00 DegT/DnrJ/EryC1/StrS family protein YP_595711.1 179021 R 363253 CDS YP_595712.1 94972494 4073458 complement(180177..180551) 1 NC_008014.1 hypothetical protein 180551 4073458 LIC096 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595712.1 180177 R 363253 CDS YP_595713.1 94972495 4073505 complement(180716..181768) 1 NC_008014.1 WblB protein 181768 4073505 LIC097 Lawsonia intracellularis PHE/MN1-00 WblB protein YP_595713.1 180716 R 363253 CDS YP_595714.1 94972496 4073506 complement(182091..183431) 1 NC_008014.1 methyl-accepting chemotaxis protein 183431 4073506 LIC098 Lawsonia intracellularis PHE/MN1-00 methyl-accepting chemotaxis protein YP_595714.1 182091 R 363253 CDS YP_595715.1 94972497 4073507 complement(184429..185472) 1 NC_008014.1 hypothetical protein 185472 4073507 LIC099 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595715.1 184429 R 363253 CDS YP_595716.1 94972498 4073508 186166..186576 1 NC_008014.1 hypothetical protein 186576 4073508 LIC100 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595716.1 186166 D 363253 CDS YP_595717.1 94972499 4073509 186732..187613 1 NC_008014.1 hypothetical protein 187613 4073509 LIC101 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595717.1 186732 D 363253 CDS YP_595718.1 94972500 4073523 188379..189776 1 NC_008014.1 putative cytochrome C peroxidase 189776 yhjA 4073523 yhjA Lawsonia intracellularis PHE/MN1-00 putative cytochrome C peroxidase YP_595718.1 188379 D 363253 CDS YP_595719.1 94972501 4073517 complement(190321..192417) 1 NC_008014.1 methyl-accepting chemotaxis protein 192417 pilJ 4073517 pilJ Lawsonia intracellularis PHE/MN1-00 methyl-accepting chemotaxis protein YP_595719.1 190321 R 363253 CDS YP_595720.1 94972502 4073510 complement(193810..194466) 1 NC_008014.1 hypothetical protein 194466 4073510 LIC104 Lawsonia intracellularis PHE/MN1-00 hypothetical protein YP_595720.1 193810 R 363253 CDS