-- dump date   	20140619_130135
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
933093000001	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
933093000002	DnaA N-terminal domain; Region: DnaA_N; pfam11638
933093000003	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
933093000004	Walker A motif; other site
933093000005	ATP binding site [chemical binding]; other site
933093000006	Walker B motif; other site
933093000007	arginine finger; other site
933093000008	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
933093000009	DnaA box-binding interface [nucleotide binding]; other site
933093000010	DNA polymerase III subunit beta; Validated; Region: PRK05643
933093000011	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
933093000012	putative DNA binding surface [nucleotide binding]; other site
933093000013	dimer interface [polypeptide binding]; other site
933093000014	beta-clamp/clamp loader binding surface; other site
933093000015	beta-clamp/translesion DNA polymerase binding surface; other site
933093000016	recombination protein F; Reviewed; Region: recF; PRK00064
933093000017	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
933093000018	Walker A/P-loop; other site
933093000019	ATP binding site [chemical binding]; other site
933093000020	Q-loop/lid; other site
933093000021	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
933093000022	ABC transporter signature motif; other site
933093000023	Walker B; other site
933093000024	D-loop; other site
933093000025	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
933093000026	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
933093000027	Mg2+ binding site [ion binding]; other site
933093000028	G-X-G motif; other site
933093000029	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
933093000030	anchoring element; other site
933093000031	dimer interface [polypeptide binding]; other site
933093000032	ATP binding site [chemical binding]; other site
933093000033	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
933093000034	active site
933093000035	putative metal-binding site [ion binding]; other site
933093000036	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
933093000037	Peptidylarginine deiminase and related enzymes [Amino acid transport and metabolism]; Region: COG2957; cl01113
933093000038	Porphyromonas-type peptidyl-arginine deiminase; Region: PAD_porph; pfam04371
933093000039	arginine decarboxylase; Provisional; Region: PRK05354
933093000040	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
933093000041	dimer interface [polypeptide binding]; other site
933093000042	active site
933093000043	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
933093000044	catalytic residues [active]
933093000045	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
933093000046	N-carbamoylputrescine amidohydrolase (CPA) (class 11 nitrilases); Region: CPA; cd07573
933093000047	N-carbamoylputrescine amidase; Region: agmatine_aguB; TIGR03381
933093000048	putative active site; other site
933093000049	catalytic triad [active]
933093000050	putative dimer interface [polypeptide binding]; other site
933093000051	bacterial Hfq-like; Region: Hfq; cd01716
933093000052	hexamer interface [polypeptide binding]; other site
933093000053	Sm1 motif; other site
933093000054	RNA binding site [nucleotide binding]; other site
933093000055	Sm2 motif; other site
933093000056	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
933093000057	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
933093000058	HflX GTPase family; Region: HflX; cd01878
933093000059	G1 box; other site
933093000060	GTP/Mg2+ binding site [chemical binding]; other site
933093000061	Switch I region; other site
933093000062	G2 box; other site
933093000063	G3 box; other site
933093000064	Switch II region; other site
933093000065	G4 box; other site
933093000066	G5 box; other site
933093000067	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
933093000068	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
933093000069	catalytic residues [active]
933093000070	Pirin-related protein [General function prediction only]; Region: COG1741
933093000071	Pirin; Region: Pirin; pfam02678
933093000072	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
933093000073	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
933093000074	Hypothetical patatin similar to Z1214 protein of Escherichia coli; Region: Pat_hypo_Ecoli_Z1214_like; cd07209
933093000075	active site
933093000076	nucleophile elbow; other site
933093000077	Patatin phospholipase; Region: DUF3734; pfam12536
933093000078	efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998
933093000079	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
933093000080	HlyD family secretion protein; Region: HlyD_3; pfam13437
933093000081	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
933093000082	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
933093000083	Zinc metalloprotease (elastase) [Amino acid transport and metabolism]; Region: LasB; COG3227
933093000084	Fungalysin/Thermolysin Propeptide Motif; Region: FTP; pfam07504
933093000085	Peptidase M4 family includes thermolysin, protealysin, aureolysin and neutral protease; Region: M4_neutral_protease; cd09597
933093000086	active site
933093000087	Zn binding site [ion binding]; other site
933093000088	hypothetical protein; Provisional; Region: PRK05255
933093000089	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
933093000090	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
933093000091	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
933093000092	Methyltransferase domain; Region: Methyltransf_26; pfam13659
933093000093	Protein of unknown function (DUF962); Region: DUF962; cl01879
933093000094	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
933093000095	amino acid transporter; Region: 2A0306; TIGR00909
933093000096	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
933093000097	Phosphate transporter family; Region: PHO4; pfam01384
933093000098	Demethoxyubiquinone hydroxylase, ferritin-like diiron-binding domain; Region: DMQH; cd01042
933093000099	diiron binding motif [ion binding]; other site
933093000100	PAS domain; Region: PAS_9; pfam13426
933093000101	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
933093000102	putative active site [active]
933093000103	heme pocket [chemical binding]; other site
933093000104	PAS domain S-box; Region: sensory_box; TIGR00229
933093000105	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
933093000106	putative active site [active]
933093000107	heme pocket [chemical binding]; other site
933093000108	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
933093000109	PAS domain; Region: PAS_9; pfam13426
933093000110	putative active site [active]
933093000111	heme pocket [chemical binding]; other site
933093000112	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
933093000113	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
933093000114	metal binding site [ion binding]; metal-binding site
933093000115	active site
933093000116	I-site; other site
933093000117	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
933093000118	potential protein location (hypothetical protein) that overlaps protein (hypothetical protein)
933093000119	M28 Zn-Peptidase Aeromonas (Vibrio) proteolytica aminopeptidase; Region: M28_AAP; cd03879
933093000120	Peptidase family M28; Region: Peptidase_M28; pfam04389
933093000121	active site
933093000122	metal binding site [ion binding]; metal-binding site
933093000123	Protein of unknown function (DUF2490); Region: DUF2490; pfam10677
933093000124	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
933093000125	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
933093000126	substrate binding pocket [chemical binding]; other site
933093000127	membrane-bound complex binding site; other site
933093000128	hinge residues; other site
933093000129	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
933093000130	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
933093000131	Predicted membrane-bound metal-dependent hydrolase (DUF457); Region: DUF457; pfam04307
933093000132	Metallo-peptidase family M12B Reprolysin-like; Region: Reprolysin_2; pfam13574
933093000133	active site
933093000134	Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family; Region: GPI-anchored; pfam10342
933093000135	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
933093000136	Bestrophin, RFP-TM, chloride channel; Region: Bestrophin; cl01544
933093000137	Sterol desaturase [Lipid metabolism]; Region: ERG3; COG3000
933093000138	Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; pfam04116
933093000139	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
933093000140	Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and...; Region: LbH_XAT; cd03349
933093000141	trimer interface [polypeptide binding]; other site
933093000142	active site
933093000143	substrate binding site [chemical binding]; other site
933093000144	CoA binding site [chemical binding]; other site
933093000145	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
933093000146	amino acid transporter; Region: 2A0306; TIGR00909
933093000147	Domain of unknown function (DUF4396); Region: DUF4396; pfam14342
933093000148	Predicted membrane protein [Function unknown]; Region: COG2323
933093000149	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
933093000150	tetramer interface [polypeptide binding]; other site
933093000151	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
933093000152	active site
933093000153	Mg2+/Mn2+ binding site [ion binding]; other site
933093000154	Domain of Unknown Function with PDB structure (DUF3865); Region: DUF3865; pfam12981
933093000155	Transcriptional regulator [Transcription]; Region: LysR; COG0583
933093000156	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
933093000157	LysR substrate binding domain; Region: LysR_substrate; pfam03466
933093000158	dimerization interface [polypeptide binding]; other site
933093000159	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296
933093000160	putative active site [active]
933093000161	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296
933093000162	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296
933093000163	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
933093000164	Helix-Turn-Helix DNA binding domain of the MerR1 transcription regulator; Region: HTH_MerR1; cd04783
933093000165	DNA binding residues [nucleotide binding]
933093000166	dimer interface [polypeptide binding]; other site
933093000167	mercury binding site [ion binding]; other site
933093000168	Glutaredoxin and related proteins [Posttranslational modification, protein turnover, chaperones]; Region: GrxC; COG0695
933093000169	Predicted membrane protein [Function unknown]; Region: COG3428
933093000170	S-AdoMet dependent tetrapyrrole methylases; Region: TP_methylase; cl00304
933093000171	active site
933093000172	SAM binding site [chemical binding]; other site
933093000173	homodimer interface [polypeptide binding]; other site
933093000174	Major Facilitator Superfamily; Region: MFS_1; pfam07690
933093000175	Class-II DAHP synthetase family; Region: DAHP_synth_2; pfam01474
933093000176	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
933093000177	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
933093000178	Predicted esterase of the alpha/beta hydrolase fold [General function prediction only]; Region: COG3545
933093000179	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
933093000180	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
933093000181	EamA-like transporter family; Region: EamA; pfam00892
933093000182	EamA-like transporter family; Region: EamA; pfam00892
933093000183	aspartate aminotransferase; Provisional; Region: PRK05764
933093000184	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
933093000185	pyridoxal 5'-phosphate binding site [chemical binding]; other site
933093000186	homodimer interface [polypeptide binding]; other site
933093000187	catalytic residue [active]
933093000188	potential protein location (hypothetical protein) that overlaps protein (aspartate aminotransferase A)
933093000189	excinuclease ABC subunit B; Provisional; Region: PRK05298
933093000190	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
933093000191	ATP binding site [chemical binding]; other site
933093000192	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
933093000193	nucleotide binding region [chemical binding]; other site
933093000194	ATP-binding site [chemical binding]; other site
933093000195	Ultra-violet resistance protein B; Region: UvrB; pfam12344
933093000196	UvrB/uvrC motif; Region: UVR; pfam02151
933093000197	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
933093000198	metal binding site [ion binding]; metal-binding site
933093000199	active site
933093000200	I-site; other site
933093000201	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
933093000202	Glutamate synthase domain 2 [Amino acid transport and metabolism]; Region: GltB; COG0069
933093000203	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
933093000204	active site
933093000205	FMN binding site [chemical binding]; other site
933093000206	substrate binding site [chemical binding]; other site
933093000207	3Fe-4S cluster binding site [ion binding]; other site
933093000208	Cell division protein ZapA; Region: ZapA; pfam05164
933093000209	Uncharacterized protein family (UPF0149); Region: UPF0149; cl01173
933093000210	proline aminopeptidase P II; Provisional; Region: PRK10879
933093000211	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
933093000212	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
933093000213	active site
933093000214	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
933093000215	2-polyprenyl-6-methoxyphenol 4-hydroxylase; Region: UbiH; TIGR01984
933093000216	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
933093000217	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
933093000218	alpha-L-glutamate ligase-related protein; Region: rimK_rel_E_lig; TIGR02291
933093000219	Inactive transglutaminase fused to 7 transmembrane helices; Region: Transglut_i_TM; pfam14400
933093000220	7 transmembrane helices usually fused to an inactive transglutaminase; Region: 7TM_transglut; pfam14402
933093000221	Uncharacterized protein conserved in archaea [Posttranslational modification, protein turnover, chaperones]; Region: COG4067
933093000222	Protein of unknown function (DUF4254); Region: DUF4254; pfam14063
933093000223	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
933093000224	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
933093000225	substrate binding pocket [chemical binding]; other site
933093000226	membrane-bound complex binding site; other site
933093000227	hinge residues; other site
933093000228	Uncharacterized BCR, YaiI/YqxD family COG1671; Region: DUF188; pfam02639
933093000229	ribonuclease R; Region: RNase_R; TIGR02063
933093000230	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
933093000231	RNB domain; Region: RNB; pfam00773
933093000232	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
933093000233	RNA binding site [nucleotide binding]; other site
933093000234	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
933093000235	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
933093000236	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
933093000237	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
933093000238	tetramer (dimer of dimers) interface [polypeptide binding]; other site
933093000239	active site
933093000240	dimer interface [polypeptide binding]; other site
933093000241	5' nucleotidase family; Region: 5_nucleotid; cl17687
933093000242	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
933093000243	Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824
933093000244	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
933093000245	PhnA protein; Region: PhnA; pfam03831
933093000246	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
933093000247	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
933093000248	active site
933093000249	phosphorylation site [posttranslational modification]
933093000250	intermolecular recognition site; other site
933093000251	DNA polymerase I; Provisional; Region: PRK05755
933093000252	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
933093000253	active site
933093000254	metal binding site 1 [ion binding]; metal-binding site
933093000255	putative 5' ssDNA interaction site; other site
933093000256	metal binding site 3; metal-binding site
933093000257	metal binding site 2 [ion binding]; metal-binding site
933093000258	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
933093000259	putative DNA binding site [nucleotide binding]; other site
933093000260	putative metal binding site [ion binding]; other site
933093000261	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
933093000262	active site
933093000263	catalytic site [active]
933093000264	substrate binding site [chemical binding]; other site
933093000265	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
933093000266	active site
933093000267	DNA binding site [nucleotide binding]
933093000268	catalytic site [active]
933093000269	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
933093000270	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
933093000271	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
933093000272	trimer interface [polypeptide binding]; other site
933093000273	active site
933093000274	UDP-GlcNAc binding site [chemical binding]; other site
933093000275	lipid binding site [chemical binding]; lipid-binding site
933093000276	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
933093000277	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
933093000278	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
933093000279	dimer interface [polypeptide binding]; other site
933093000280	active site
933093000281	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
933093000282	Coenzyme A binding pocket [chemical binding]; other site
933093000283	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
933093000284	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
933093000285	Coenzyme A binding pocket [chemical binding]; other site
933093000286	Peptide methionine sulfoxide reductase; Region: PMSR; pfam01625
933093000287	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
933093000288	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
933093000289	Uncharacterized ACR, YagE family COG1723; Region: DUF155; pfam02582
933093000290	potential protein location (hypothetical protein) that overlaps protein (hypothetical protein)
933093000291	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
933093000292	Isoprenoid Biosynthesis enzymes, Class 1; Region: Isoprenoid_Biosyn_C1; cl00210
933093000293	substrate binding pocket [chemical binding]; other site
933093000294	substrate-Mg2+ binding site; other site
933093000295	aspartate-rich region 1; other site
933093000296	aspartate-rich region 2; other site
933093000297	Predicted signal transduction protein containing EAL and modified HD-GYP domains [Signal transduction mechanisms]; Region: COG3434
933093000298	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
933093000299	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
933093000300	tetramer interface [polypeptide binding]; other site
933093000301	pyridoxal 5'-phosphate binding site [chemical binding]; other site
933093000302	catalytic residue [active]
933093000303	YCII-related domain; Region: YCII; cl00999
933093000304	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain [Amino acid transport and metabolism]; Region: GcvP; COG0403
933093000305	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
933093000306	tetramer interface [polypeptide binding]; other site
933093000307	pyridoxal 5'-phosphate binding site [chemical binding]; other site
933093000308	catalytic residue [active]
933093000309	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
933093000310	lipoyl attachment site [posttranslational modification]; other site
933093000311	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
933093000312	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
933093000313	Protein of unknown function (DUF3592); Region: DUF3592; pfam12158
933093000314	Macrophage killing protein with similarity to conjugation protein; Region: IcmL; pfam11393
933093000315	ABC-type anion transport system, duplicated permease component [Inorganic ion transport and metabolism]; Region: COG4986
933093000316	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
933093000317	dimer interface [polypeptide binding]; other site
933093000318	conserved gate region; other site
933093000319	putative PBP binding loops; other site
933093000320	ABC-ATPase subunit interface; other site
933093000321	Binding-protein-dependent transport system inner membrane component; Region: BPD_transp_1; pfam00528
933093000322	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
933093000323	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
933093000324	Walker A/P-loop; other site
933093000325	ATP binding site [chemical binding]; other site
933093000326	Q-loop/lid; other site
933093000327	ABC transporter signature motif; other site
933093000328	Walker B; other site
933093000329	D-loop; other site
933093000330	H-loop/switch region; other site
933093000331	ABC nitrate/sulfonate/bicarbonate family transporter, ATPase subunit; Region: ABC_transp; pfam09821
933093000332	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
933093000333	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
933093000334	catalytic residues [active]
933093000335	hinge region; other site
933093000336	alpha helical domain; other site
933093000337	Cytochrome c553 [Energy production and conversion]; Region: COG2863
933093000338	Cytochrome c; Region: Cytochrom_C; cl11414
933093000339	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
933093000340	G1 box; other site
933093000341	GTP/Mg2+ binding site [chemical binding]; other site
933093000342	Switch I region; other site
933093000343	G2 box; other site
933093000344	G3 box; other site
933093000345	Switch II region; other site
933093000346	G4 box; other site
933093000347	G5 box; other site
933093000348	acetyl-CoA synthetase; Provisional; Region: PRK00174
933093000349	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
933093000350	active site
933093000351	CoA binding site [chemical binding]; other site
933093000352	acyl-activating enzyme (AAE) consensus motif; other site
933093000353	AMP binding site [chemical binding]; other site
933093000354	acetate binding site [chemical binding]; other site
933093000355	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
933093000356	3-hydroxyisobutyrate dehydrogenase; Region: HIBADH; TIGR01692
933093000357	Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2; Region: ALDH_F6_MMSDH; cd07085
933093000358	methylmalonic acid semialdehyde dehydrogenase; Region: MMSDH; TIGR01722
933093000359	tetrameric interface [polypeptide binding]; other site
933093000360	NAD binding site [chemical binding]; other site
933093000361	catalytic residues [active]
933093000362	dihydrodipicolinate reductase; Provisional; Region: PRK00048
933093000363	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
933093000364	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
933093000365	ProQ/FINO family; Region: ProQ; smart00945
933093000366	putative RNA binding sites [nucleotide binding]; other site
933093000367	MltA specific insert domain; Region: MltA; cl08398
933093000368	Peptidase S46; Region: Peptidase_S46; pfam10459
933093000369	pyruvate kinase; Provisional; Region: PRK05826
933093000370	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
933093000371	domain interfaces; other site
933093000372	active site
933093000373	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
933093000374	Phosphoglycerate kinase; Region: PGK; pfam00162
933093000375	substrate binding site [chemical binding]; other site
933093000376	hinge regions; other site
933093000377	ADP binding site [chemical binding]; other site
933093000378	catalytic site [active]
933093000379	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
933093000380	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
933093000381	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
933093000382	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
933093000383	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
933093000384	TPP-binding site [chemical binding]; other site
933093000385	dimer interface [polypeptide binding]; other site
933093000386	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
933093000387	PYR/PP interface [polypeptide binding]; other site
933093000388	dimer interface [polypeptide binding]; other site
933093000389	TPP binding site [chemical binding]; other site
933093000390	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
933093000391	Zn-dependent oligopeptidases [Amino acid transport and metabolism]; Region: Dcp; COG0339
933093000392	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
933093000393	active site
933093000394	Zn binding site [ion binding]; other site
933093000395	Transposase Tn5 dimerisation domain; Region: Dimer_Tnp_Tn5; pfam02281
933093000396	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
933093000397	Transposase; Region: DDE_Tnp_ISL3; pfam01610
933093000398	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
933093000399	Transposase; Region: DDE_Tnp_ISL3; pfam01610
933093000400	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
933093000401	putative transposase OrfB; Reviewed; Region: PHA02517
933093000402	HTH-like domain; Region: HTH_21; pfam13276
933093000403	Integrase core domain; Region: rve; pfam00665
933093000404	Integrase core domain; Region: rve_2; pfam13333
933093000405	Transposase; Region: HTH_Tnp_1; pfam01527
933093000406	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
933093000407	Predicted P-loop ATPase [General function prediction only]; Region: COG4928
933093000408	KAP family P-loop domain; Region: KAP_NTPase; pfam07693
933093000409	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
933093000410	Coenzyme A binding pocket [chemical binding]; other site
933093000411	PAS domain; Region: PAS_9; pfam13426
933093000412	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
933093000413	putative active site [active]
933093000414	heme pocket [chemical binding]; other site
933093000415	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
933093000416	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
933093000417	metal binding site [ion binding]; metal-binding site
933093000418	active site
933093000419	I-site; other site
933093000420	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
933093000421	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
933093000422	active site
933093000423	Protein of unknown function (DUF3423); Region: DUF3423; pfam11903
933093000424	Uncharacterized conserved protein [Function unknown]; Region: COG0432
933093000425	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
933093000426	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
933093000427	potential protein location (hypothetical protein) that overlaps protein (hydrolase of the alpha/beta superfamily)
933093000428	Peptidase propeptide and YPEB domain; Region: PepSY_2; pfam13670
933093000429	Peptidase propeptide and YPEB domain; Region: PepSY_2; pfam13670
933093000430	Protein of unknown function (DUF808); Region: DUF808; pfam05661
933093000431	RF-1 domain; Region: RF-1; pfam00472
933093000432	Protein of unknown function (DUF330); Region: DUF330; pfam03886
933093000433	mce related protein; Region: MCE; pfam02470
933093000434	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
933093000435	Permease; Region: Permease; pfam02405
933093000436	F-box-like; Region: F-box-like; pfam12937
933093000437	Transcriptional regulator [Transcription]; Region: LysR; COG0583
933093000438	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
933093000439	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
933093000440	dimerization interface [polypeptide binding]; other site
933093000441	Pyoverdine/dityrosine biosynthesis protein; Region: DIT1_PvcA; pfam05141
933093000442	Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175
933093000443	Taurine catabolism dioxygenase TauD, TfdA family; Region: TauD; pfam02668
933093000444	substrate binding pocket [chemical binding]; other site
933093000445	active site
933093000446	iron coordination sites [ion binding]; other site
933093000447	hypothetical protein; Provisional; Region: PRK07190
933093000448	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
933093000449	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
933093000450	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
933093000451	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093000452	putative substrate translocation pore; other site
933093000453	hypothetical protein; Provisional; Region: PRK07206
933093000454	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
933093000455	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
933093000456	S-adenosylmethionine binding site [chemical binding]; other site
933093000457	M48 family peptidase; Provisional; Region: PRK03001
933093000458	Predicted NAD/FAD-binding protein [General function prediction only]; Region: COG2907
933093000459	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
933093000460	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
933093000461	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
933093000462	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
933093000463	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
933093000464	Walker A/P-loop; other site
933093000465	ATP binding site [chemical binding]; other site
933093000466	Q-loop/lid; other site
933093000467	ABC transporter signature motif; other site
933093000468	Walker B; other site
933093000469	D-loop; other site
933093000470	H-loop/switch region; other site
933093000471	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
933093000472	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
933093000473	TM-ABC transporter signature motif; other site
933093000474	hypothetical protein; Provisional; Region: PRK09133
933093000475	M20 Peptidase, carboxypeptidase yscS-like; Region: M20_yscS_like; cd05675
933093000476	putative metal binding site [ion binding]; other site
933093000477	Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804
933093000478	CoA-transferase family III; Region: CoA_transf_3; pfam02515
933093000479	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
933093000480	Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain  (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464
933093000481	putative dimer interface [polypeptide binding]; other site
933093000482	N-terminal catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_1; cd00649
933093000483	dimer interface [polypeptide binding]; other site
933093000484	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
933093000485	active site
933093000486	heme binding site [chemical binding]; other site
933093000487	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
933093000488	Putative heavy-metal-binding; Region: YbjQ_1; cl00426
933093000489	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3397
933093000490	Chitin binding domain; Region: Chitin_bind_3; pfam03067
933093000491	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
933093000492	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
933093000493	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
933093000494	Protein of unknown function (DUF1295); Region: DUF1295; cl17837
933093000495	Protein of unknown function (DUF2878); Region: DUF2878; pfam11086
933093000496	Predicted kinase related to dihydroxyacetone kinase [General function prediction only]; Region: COG1461
933093000497	DAK2 domain; Region: Dak2; pfam02734
933093000498	EDD domain protein, DegV family; Region: DegV; TIGR00762
933093000499	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
933093000500	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
933093000501	classical (c) SDRs; Region: SDR_c; cd05233
933093000502	NAD(P) binding site [chemical binding]; other site
933093000503	active site
933093000504	Uncharacterized protein related to deoxyribodipyrimidine photolyase [General function prediction only]; Region: COG3046
933093000505	Deoxyribodipyrimidine photo-lyase-related protein; Region: DPRP; pfam04244
933093000506	Predicted membrane protein (DUF2177); Region: DUF2177; pfam09945
933093000507	Catalytic domain of Protein Kinases; Region: PKc; cd00180
933093000508	Serine/threonine protein kinase [General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair]; Region: SPS1; COG0515
933093000509	active site
933093000510	ATP binding site [chemical binding]; other site
933093000511	substrate binding site [chemical binding]; other site
933093000512	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
933093000513	substrate binding site [chemical binding]; other site
933093000514	activation loop (A-loop); other site
933093000515	activation loop (A-loop); other site
933093000516	TspO/MBR family; Region: TspO_MBR; pfam03073
933093000517	Deoxyribodipyrimidine photolyase [DNA replication, recombination, and repair]; Region: PhrB; COG0415
933093000518	DNA photolyase; Region: DNA_photolyase; pfam00875
933093000519	Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346
933093000520	Putative effector of murein hydrolase LrgA [General function prediction only]; Region: COG1380
933093000521	Transcriptional regulator [Transcription]; Region: LysR; COG0583
933093000522	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
933093000523	The C-terminal substrate binding domain of LysR-like transcriptional regulator CidR, contains the type 2 periplasmic binding fold; Region: PBP2_CidR; cd08438
933093000524	putative dimerization interface [polypeptide binding]; other site
933093000525	Domain of unknown function (DUF329); Region: DUF329; pfam03884
933093000526	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
933093000527	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
933093000528	NAD binding site [chemical binding]; other site
933093000529	ATP-grasp domain; Region: ATP-grasp; pfam02222
933093000530	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
933093000531	Nitrogen regulatory protein P-II; Region: P-II; cl00412
933093000532	Uncharacterized protein conserved in bacteria (DUF2309); Region: DUF2309; pfam10070
933093000533	Uncharacterized protein conserved in bacteria (DUF2309); Region: DUF2309; pfam10070
933093000534	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
933093000535	Transcriptional regulator [Transcription]; Region: LysR; COG0583
933093000536	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
933093000537	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
933093000538	dimerization interface [polypeptide binding]; other site
933093000539	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
933093000540	ATP binding site [chemical binding]; other site
933093000541	Q-loop/lid; other site
933093000542	ABC transporter signature motif; other site
933093000543	Walker B; other site
933093000544	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
933093000545	HlyD family secretion protein; Region: HlyD_3; pfam13437
933093000546	Outer membrane efflux protein; Region: OEP; pfam02321
933093000547	Outer membrane efflux protein; Region: OEP; pfam02321
933093000548	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
933093000549	hypothetical protein; Provisional; Region: PHA02764
933093000550	Heme oxygenase catalyzes the rate limiting step in the degradation of heme to bilirubin, it is essential for recycling of iron from heme. Heme is used as a substrate and cofactor for its own degradation to biliverdin, iron, and carbon monoxide. This...; Region: HemeO; cl17299
933093000551	heme binding pocket [chemical binding]; other site
933093000552	heme ligand [chemical binding]; other site
933093000553	CHASE3 domain; Region: CHASE3; pfam05227
933093000554	GAF domain; Region: GAF_3; pfam13492
933093000555	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
933093000556	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
933093000557	metal binding site [ion binding]; metal-binding site
933093000558	active site
933093000559	I-site; other site
933093000560	copper-(or silver)-translocating P-type ATPase; Region: ATPase-IB1_Cu; TIGR01511
933093000561	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
933093000562	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
933093000563	motif II; other site
933093000564	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
933093000565	metal binding site 2 [ion binding]; metal-binding site
933093000566	putative DNA binding helix; other site
933093000567	metal binding site 1 [ion binding]; metal-binding site
933093000568	dimer interface [polypeptide binding]; other site
933093000569	structural Zn2+ binding site [ion binding]; other site
933093000570	Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvB; COG0028
933093000571	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
933093000572	PYR/PP interface [polypeptide binding]; other site
933093000573	dimer interface [polypeptide binding]; other site
933093000574	TPP binding site [chemical binding]; other site
933093000575	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
933093000576	Thiamine pyrophosphate (TPP) family, BFDC subfamily, TPP-binding module; composed of proteins similar to Pseudomonas putida benzoylformate decarboxylase (BFDC). P. putida BFDC plays a role in the mandelate pathway, catalyzing the conversion of...; Region: TPP_BFDC; cd02002
933093000577	TPP-binding site [chemical binding]; other site
933093000578	dimer interface [polypeptide binding]; other site
933093000579	Dot/Icm substrate protein; Region: SidE; pfam12252
933093000580	Glutathione-dependent formaldehyde-activating enzyme; Region: GFA; cl01553
933093000581	3-oxoadipate enol-lactonase; Region: protocat_pcaD; TIGR02427
933093000582	Bacillus subtilis NAD+-dependent betaine aldehyde dehydrogenase-like; Region: ALDH_BADH-GbsA; cd07119
933093000583	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
933093000584	tetramerization interface [polypeptide binding]; other site
933093000585	NAD(P) binding site [chemical binding]; other site
933093000586	catalytic residues [active]
933093000587	4-aminobutyrate aminotransferase; Provisional; Region: PRK06058
933093000588	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
933093000589	inhibitor-cofactor binding pocket; inhibition site
933093000590	pyridoxal 5'-phosphate binding site [chemical binding]; other site
933093000591	catalytic residue [active]
933093000592	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
933093000593	glutaminase A; Region: Gln_ase; TIGR03814
933093000594	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
933093000595	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
933093000596	NAD binding site [chemical binding]; other site
933093000597	Lin1944 and related proteins, classical (c) SDRs; Region: Lin1944_like_SDR_c; cd11731
933093000598	putative NAD(P) binding site [chemical binding]; other site
933093000599	homodimer interface [polypeptide binding]; other site
933093000600	mercuric reductase; Validated; Region: PRK06370
933093000601	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
933093000602	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
933093000603	Bacterial NAD-glutamate dehydrogenase; Region: Bac_GDH; pfam05088
933093000604	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Region: ELFV_dehydrog; smart00839
933093000605	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
933093000606	ArsC family; Region: ArsC; pfam03960
933093000607	catalytic residues [active]
933093000608	Fatty acid desaturase; Region: FA_desaturase; pfam00487
933093000609	The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide...; Region: Delta9-FADS-like; cd03505
933093000610	Di-iron ligands [ion binding]; other site
933093000611	Transposase; Region: DDE_Tnp_ISL3; pfam01610
933093000612	helicase 45; Provisional; Region: PTZ00424
933093000613	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
933093000614	ATP binding site [chemical binding]; other site
933093000615	Mg++ binding site [ion binding]; other site
933093000616	motif III; other site
933093000617	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
933093000618	nucleotide binding region [chemical binding]; other site
933093000619	ATP-binding site [chemical binding]; other site
933093000620	RNA-binding proteins (RRM domain) [General function prediction only]; Region: COG0724
933093000621	RNA recognition motif in Helicobacter pylori HP0827 protein and similar proteins; Region: RRM_HP0827_like; cd12399
933093000622	hypothetical protein; Provisional; Region: PRK11212
933093000623	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
933093000624	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
933093000625	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
933093000626	HlyD family secretion protein; Region: HlyD; pfam00529
933093000627	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
933093000628	HlyD family secretion protein; Region: HlyD_3; pfam13437
933093000629	Family 4 Uracil-DNA glycosylase (UDG), found exclusively in thermophilic organisms; Region: UDG_F4_TTUDGA_like; cd10030
933093000630	Fe-S cluster binding site [ion binding]; other site
933093000631	active site
933093000632	Permeases of the major facilitator superfamily [General function prediction only]; Region: COG2270
933093000633	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
933093000634	amidase catalytic site [active]
933093000635	Zn binding residues [ion binding]; other site
933093000636	substrate binding site [chemical binding]; other site
933093000637	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
933093000638	Putative multicopper oxidases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: SufI; COG2132
933093000639	Multicopper oxidase; Region: Cu-oxidase; pfam00394
933093000640	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
933093000641	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
933093000642	Thermotoga maritima CorA-like family; Region: TmCorA-like; cd12822
933093000643	oligomer interface [polypeptide binding]; other site
933093000644	metal binding site [ion binding]; metal-binding site
933093000645	metal binding site [ion binding]; metal-binding site
933093000646	putative Cl binding site [ion binding]; other site
933093000647	aspartate ring; other site
933093000648	hydrophobic gate; other site
933093000649	basic sphincter; other site
933093000650	periplasmic entrance; other site
933093000651	HD domain; Region: HD_3; pfam13023
933093000652	Bacterial protein of unknown function (DUF853); Region: DUF853; pfam05872
933093000653	Zonular occludens toxin (Zot); Region: Zot; cl17485
933093000654	nicotinate phosphoribosyltransferase; Validated; Region: PRK09243
933093000655	Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction...; Region: NAPRTase_A; cd01570
933093000656	active site
933093000657	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
933093000658	Isochorismatase family; Region: Isochorismatase; pfam00857
933093000659	catalytic triad [active]
933093000660	metal binding site [ion binding]; metal-binding site
933093000661	conserved cis-peptide bond; other site
933093000662	ChaP, an enzyme involved in the biosynthesis of the antitumor agent chartreusin (cha); and similar proteins; Region: ChaP_like; cd08351
933093000663	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
933093000664	metal binding site [ion binding]; metal-binding site
933093000665	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093000666	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
933093000667	putative substrate translocation pore; other site
933093000668	Transcriptional regulator [Transcription]; Region: LysR; COG0583
933093000669	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
933093000670	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
933093000671	putative effector binding pocket; other site
933093000672	dimerization interface [polypeptide binding]; other site
933093000673	Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking; Region: RasGEF; cl02485
933093000674	Ras interaction site [polypeptide binding]; other site
933093000675	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
933093000676	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
933093000677	active site
933093000678	phosphorylation site [posttranslational modification]
933093000679	intermolecular recognition site; other site
933093000680	dimerization interface [polypeptide binding]; other site
933093000681	PAS domain; Region: PAS; smart00091
933093000682	PAS fold; Region: PAS_7; pfam12860
933093000683	putative active site [active]
933093000684	heme pocket [chemical binding]; other site
933093000685	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
933093000686	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
933093000687	metal binding site [ion binding]; metal-binding site
933093000688	active site
933093000689	I-site; other site
933093000690	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
933093000691	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
933093000692	PAS fold; Region: PAS_3; pfam08447
933093000693	putative active site [active]
933093000694	heme pocket [chemical binding]; other site
933093000695	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
933093000696	ATP binding site [chemical binding]; other site
933093000697	Mg2+ binding site [ion binding]; other site
933093000698	G-X-G motif; other site
933093000699	FIST N domain; Region: FIST; pfam08495
933093000700	Uncharacterized conserved protein [Function unknown]; Region: COG3287
933093000701	FIST C domain; Region: FIST_C; pfam10442
933093000702	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
933093000703	aminoethylphosphonate catabolism associated LysR family transcriptional regulator; Region: phn_lysR; TIGR03339
933093000704	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
933093000705	dimerization interface [polypeptide binding]; other site
933093000706	amino acid transporter; Region: 2A0306; TIGR00909
933093000707	Methyltransferase domain; Region: Methyltransf_31; pfam13847
933093000708	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
933093000709	S-adenosylmethionine binding site [chemical binding]; other site
933093000710	formate dehydrogenase; Provisional; Region: PRK07574
933093000711	NAD-dependent Formate Dehydrogenase (FDH); Region: FDH; cd05302
933093000712	dimerization interface [polypeptide binding]; other site
933093000713	ligand binding site [chemical binding]; other site
933093000714	NAD binding site [chemical binding]; other site
933093000715	catalytic site [active]
933093000716	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
933093000717	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
933093000718	putative NAD(P) binding site [chemical binding]; other site
933093000719	homodimer interface [polypeptide binding]; other site
933093000720	homotetramer interface [polypeptide binding]; other site
933093000721	active site
933093000722	elongation factor P; Validated; Region: PRK00529
933093000723	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
933093000724	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
933093000725	RNA binding site [nucleotide binding]; other site
933093000726	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
933093000727	RNA binding site [nucleotide binding]; other site
933093000728	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cl15377
933093000729	Radical SAM superfamily; Region: Radical_SAM; pfam04055
933093000730	polyphosphate kinase; Provisional; Region: PRK05443
933093000731	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
933093000732	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
933093000733	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
933093000734	putative active site [active]
933093000735	catalytic site [active]
933093000736	Catalytic C-terminal domain, second repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C2_like; cd09168
933093000737	putative domain interface [polypeptide binding]; other site
933093000738	putative active site [active]
933093000739	catalytic site [active]
933093000740	Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396
933093000741	nucleophile elbow; other site
933093000742	Chromate transporter; Region: Chromate_transp; pfam02417
933093000743	acyl-CoA dehydrogenase; Reviewed; Region: PRK13026
933093000744	Acyl-CoA dehydrogenase, N-terminal domain; Region: Acyl-CoA_dh_N; pfam02771
933093000745	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
933093000746	active site
933093000747	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
933093000748	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
933093000749	NTP_transferase_like_1 is a member of the nucleotidyl transferase family; Region: NTP_transferase_like_1; cd06422
933093000750	Substrate binding site; other site
933093000751	metal-binding site
933093000752	Predicted phosphotransferase related to Ser/Thr protein kinases [General function prediction only]; Region: COG3178
933093000753	Phosphotransferase enzyme family; Region: APH; pfam01636
933093000754	Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452
933093000755	OstA-like protein; Region: OstA; cl00844
933093000756	Organic solvent tolerance protein; Region: OstA_C; pfam04453
933093000757	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
933093000758	SurA N-terminal domain; Region: SurA_N; pfam09312
933093000759	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
933093000760	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
933093000761	4-hydroxythreonine-4-phosphate dehydrogenase; Region: pdxA; TIGR00557
933093000762	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
933093000763	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
933093000764	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
933093000765	folate binding site [chemical binding]; other site
933093000766	NADP+ binding site [chemical binding]; other site
933093000767	Repeats found in Drosophila proteins; Region: DM9; smart00696
933093000768	Protein of unknown function (DUF3421); Region: DUF3421; pfam11901
933093000769	Repeats found in Drosophila proteins; Region: DM9; smart00696
933093000770	potential protein location (hypothetical protein lp12_0308 [Legionella pneumophila subsp. pneumophila ATCC 43290]) that overlaps RNA (23S ribosomal RNA)
933093000771	potential protein location (hypothetical protein lp12_0309 [Legionella pneumophila subsp. pneumophila ATCC 43290]) that overlaps RNA (23S ribosomal RNA)
933093000772	elongation factor Tu; Reviewed; Region: PRK00049
933093000773	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
933093000774	G1 box; other site
933093000775	GEF interaction site [polypeptide binding]; other site
933093000776	GTP/Mg2+ binding site [chemical binding]; other site
933093000777	Switch I region; other site
933093000778	G2 box; other site
933093000779	G3 box; other site
933093000780	Switch II region; other site
933093000781	G4 box; other site
933093000782	G5 box; other site
933093000783	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
933093000784	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
933093000785	Antibiotic Binding Site [chemical binding]; other site
933093000786	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
933093000787	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
933093000788	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
933093000789	putative homodimer interface [polypeptide binding]; other site
933093000790	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
933093000791	heterodimer interface [polypeptide binding]; other site
933093000792	homodimer interface [polypeptide binding]; other site
933093000793	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
933093000794	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
933093000795	23S rRNA interface [nucleotide binding]; other site
933093000796	L7/L12 interface [polypeptide binding]; other site
933093000797	putative thiostrepton binding site; other site
933093000798	L25 interface [polypeptide binding]; other site
933093000799	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
933093000800	mRNA/rRNA interface [nucleotide binding]; other site
933093000801	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
933093000802	23S rRNA interface [nucleotide binding]; other site
933093000803	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
933093000804	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
933093000805	peripheral dimer interface [polypeptide binding]; other site
933093000806	core dimer interface [polypeptide binding]; other site
933093000807	L10 interface [polypeptide binding]; other site
933093000808	L11 interface [polypeptide binding]; other site
933093000809	putative EF-Tu interaction site [polypeptide binding]; other site
933093000810	putative EF-G interaction site [polypeptide binding]; other site
933093000811	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
933093000812	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
933093000813	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
933093000814	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
933093000815	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
933093000816	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
933093000817	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
933093000818	RPB3 interaction site [polypeptide binding]; other site
933093000819	RPB1 interaction site [polypeptide binding]; other site
933093000820	RPB11 interaction site [polypeptide binding]; other site
933093000821	RPB10 interaction site [polypeptide binding]; other site
933093000822	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
933093000823	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
933093000824	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
933093000825	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
933093000826	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
933093000827	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
933093000828	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
933093000829	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
933093000830	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
933093000831	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
933093000832	DNA binding site [nucleotide binding]
933093000833	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
933093000834	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
933093000835	S17 interaction site [polypeptide binding]; other site
933093000836	S8 interaction site; other site
933093000837	16S rRNA interaction site [nucleotide binding]; other site
933093000838	streptomycin interaction site [chemical binding]; other site
933093000839	23S rRNA interaction site [nucleotide binding]; other site
933093000840	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
933093000841	30S ribosomal protein S7; Validated; Region: PRK05302
933093000842	elongation factor G; Reviewed; Region: PRK00007
933093000843	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
933093000844	G1 box; other site
933093000845	putative GEF interaction site [polypeptide binding]; other site
933093000846	GTP/Mg2+ binding site [chemical binding]; other site
933093000847	Switch I region; other site
933093000848	G2 box; other site
933093000849	G3 box; other site
933093000850	Switch II region; other site
933093000851	G4 box; other site
933093000852	G5 box; other site
933093000853	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
933093000854	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
933093000855	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
933093000856	elongation factor Tu; Reviewed; Region: PRK00049
933093000857	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
933093000858	G1 box; other site
933093000859	GEF interaction site [polypeptide binding]; other site
933093000860	GTP/Mg2+ binding site [chemical binding]; other site
933093000861	Switch I region; other site
933093000862	G2 box; other site
933093000863	G3 box; other site
933093000864	Switch II region; other site
933093000865	G4 box; other site
933093000866	G5 box; other site
933093000867	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
933093000868	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
933093000869	Antibiotic Binding Site [chemical binding]; other site
933093000870	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
933093000871	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
933093000872	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
933093000873	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
933093000874	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
933093000875	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
933093000876	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
933093000877	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
933093000878	putative translocon binding site; other site
933093000879	protein-rRNA interface [nucleotide binding]; other site
933093000880	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
933093000881	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
933093000882	G-X-X-G motif; other site
933093000883	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
933093000884	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
933093000885	23S rRNA interface [nucleotide binding]; other site
933093000886	5S rRNA interface [nucleotide binding]; other site
933093000887	putative antibiotic binding site [chemical binding]; other site
933093000888	L25 interface [polypeptide binding]; other site
933093000889	L27 interface [polypeptide binding]; other site
933093000890	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
933093000891	putative translocon interaction site; other site
933093000892	23S rRNA interface [nucleotide binding]; other site
933093000893	signal recognition particle (SRP54) interaction site; other site
933093000894	L23 interface [polypeptide binding]; other site
933093000895	trigger factor interaction site; other site
933093000896	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
933093000897	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
933093000898	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
933093000899	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
933093000900	RNA binding site [nucleotide binding]; other site
933093000901	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
933093000902	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
933093000903	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
933093000904	Ribosomal protein S14p/S29e; Region: Ribosomal_S14; cl00355
933093000905	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
933093000906	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
933093000907	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
933093000908	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
933093000909	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
933093000910	23S rRNA interface [nucleotide binding]; other site
933093000911	L21e interface [polypeptide binding]; other site
933093000912	5S rRNA interface [nucleotide binding]; other site
933093000913	L27 interface [polypeptide binding]; other site
933093000914	L5 interface [polypeptide binding]; other site
933093000915	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
933093000916	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
933093000917	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
933093000918	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
933093000919	23S rRNA binding site [nucleotide binding]; other site
933093000920	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
933093000921	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
933093000922	SecY translocase; Region: SecY; pfam00344
933093000923	50S ribosomal protein L36; Reviewed; Region: rpmJ; PRK00465
933093000924	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
933093000925	30S ribosomal protein S13; Region: bact_S13; TIGR03631
933093000926	30S ribosomal protein S11; Validated; Region: PRK05309
933093000927	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
933093000928	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
933093000929	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
933093000930	RNA binding surface [nucleotide binding]; other site
933093000931	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
933093000932	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
933093000933	alphaNTD homodimer interface [polypeptide binding]; other site
933093000934	alphaNTD - beta interaction site [polypeptide binding]; other site
933093000935	alphaNTD - beta' interaction site [polypeptide binding]; other site
933093000936	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
933093000937	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
933093000938	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
933093000939	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
933093000940	dimer interface [polypeptide binding]; other site
933093000941	ssDNA binding site [nucleotide binding]; other site
933093000942	tetramer (dimer of dimers) interface [polypeptide binding]; other site
933093000943	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093000944	Major Facilitator Superfamily; Region: MFS_1; pfam07690
933093000945	putative substrate translocation pore; other site
933093000946	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK08063
933093000947	1-cyclohexenylcarbonyl_coenzyme A_reductase (ChcA)_like, classical (c) SDRs; Region: ChcA_like_SDR_c; cd05359
933093000948	putative NAD(P) binding site [chemical binding]; other site
933093000949	active site
933093000950	Phosphopantetheine attachment site; Region: PP-binding; cl09936
933093000951	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
933093000952	active site 2 [active]
933093000953	active site 1 [active]
933093000954	FabA/Z, beta-hydroxyacyl-acyl carrier protein (ACP)-dehydratases: One of several distinct enzyme types of the dissociative, type II, fatty acid synthase system (found in bacteria and plants) required to complete successive cycles of fatty acid elongation; Region: FabA_FabZ; cd00493
933093000955	active site 2 [active]
933093000956	dimer interface [polypeptide binding]; other site
933093000957	active site 1 [active]
933093000958	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
933093000959	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
933093000960	dimer interface [polypeptide binding]; other site
933093000961	active site
933093000962	3-oxoacyl-(acyl-carrier-protein) synthase [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: FabB; COG0304
933093000963	Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the...; Region: cond_enzymes; cl09938
933093000964	active site
933093000965	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
933093000966	putative acyl-acceptor binding pocket; other site
933093000967	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
933093000968	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
933093000969	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
933093000970	Menaquinone biosynthesis; Region: VitK2_biosynth; cl17475
933093000971	Phospholipase/Carboxylesterase; Region: Abhydrolase_2; pfam02230
933093000972	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
933093000973	putative coenzyme Q binding site [chemical binding]; other site
933093000974	hypothetical protein; Validated; Region: PRK01777
933093000975	Outer membrane lipoprotein OmlA (small protein A) [Cell envelope biogenesis, outer membrane]; Region: OlmA; COG2913
933093000976	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
933093000977	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
933093000978	metal binding site 2 [ion binding]; metal-binding site
933093000979	putative DNA binding helix; other site
933093000980	metal binding site 1 [ion binding]; metal-binding site
933093000981	dimer interface [polypeptide binding]; other site
933093000982	structural Zn2+ binding site [ion binding]; other site
933093000983	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
933093000984	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
933093000985	metal binding site [ion binding]; metal-binding site
933093000986	active site
933093000987	I-site; other site
933093000988	N-formylglutamate amidohydrolase; Region: FGase; pfam05013
933093000989	Glutamate-cysteine ligase family 2(GCS2); Region: GCS2; cl00954
933093000990	RimK-like ATPgrasp N-terminal domain; Region: RLAN; pfam14401
933093000991	Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) [Coenzyme metabolism / Translation, ribosomal structure and biogenesis]; Region: RimK; COG0189
933093000992	ATP-grasp domain; Region: ATP-grasp_4; cl17255
933093000993	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
933093000994	CoenzymeA binding site [chemical binding]; other site
933093000995	subunit interaction site [polypeptide binding]; other site
933093000996	PHB binding site; other site
933093000997	BON domain; Region: BON; pfam04972
933093000998	BON domain; Region: BON; pfam04972
933093000999	Macrophage killing protein with similarity to conjugation protein; Region: IcmL; pfam11393
933093001000	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
933093001001	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
933093001002	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
933093001003	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
933093001004	Uncharacterized conserved protein [Function unknown]; Region: LemA; COG1704
933093001005	heat shock protein HtpX; Provisional; Region: PRK02870
933093001006	inner membrane transport permease; Provisional; Region: PRK15066
933093001007	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
933093001008	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
933093001009	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
933093001010	Walker A/P-loop; other site
933093001011	ATP binding site [chemical binding]; other site
933093001012	Q-loop/lid; other site
933093001013	ABC transporter signature motif; other site
933093001014	Walker B; other site
933093001015	D-loop; other site
933093001016	H-loop/switch region; other site
933093001017	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_3; pfam13640
933093001018	Protein of unknown function DUF45; Region: DUF45; pfam01863
933093001019	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
933093001020	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
933093001021	DNA binding site [nucleotide binding]
933093001022	active site
933093001023	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
933093001024	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
933093001025	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
933093001026	RimM N-terminal domain; Region: RimM; pfam01782
933093001027	PRC-barrel domain; Region: PRC; pfam05239
933093001028	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
933093001029	signal recognition particle protein; Provisional; Region: PRK10867
933093001030	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
933093001031	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
933093001032	P loop; other site
933093001033	GTP binding site [chemical binding]; other site
933093001034	Signal peptide binding domain; Region: SRP_SPB; pfam02978
933093001035	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
933093001036	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
933093001037	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
933093001038	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
933093001039	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
933093001040	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
933093001041	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
933093001042	Disulfide bond formation protein DsbB; Region: DsbB; pfam02600
933093001043	SURF1 superfamily. Surf1/Shy1 has been implicated in the posttranslational steps of the biogenesis of the mitochondrially-encoded Cox1 subunit of cytochrome c oxidase (complex IV). Cytochrome c oxidase (complex IV), the terminal electron-transferring...; Region: SURF1; cd06662
933093001044	Cytochrome oxidase assembly protein; Region: COX15-CtaA; pfam02628
933093001045	Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]; Region: CtaA; COG1612
933093001046	protoheme IX farnesyltransferase; Provisional; Region: PRK04375
933093001047	UbiA prenyltransferase family; Region: UbiA; pfam01040
933093001048	Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]; Region: COG1999
933093001049	SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968
933093001050	Cu(I) binding site [ion binding]; other site
933093001051	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
933093001052	RimK-like ATP-grasp domain; Region: RimK; pfam08443
933093001053	bifunctional HTH-domain containing protein/aminotransferase; Provisional; Region: PRK13355
933093001054	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
933093001055	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
933093001056	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
933093001057	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
933093001058	6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard...; Region: 6PGL; cd01400
933093001059	putative active site [active]
933093001060	phosphogluconate dehydratase; Validated; Region: PRK09054
933093001061	6-phosphogluconate dehydratase; Region: edd; TIGR01196
933093001062	Glucokinase; Region: Glucokinase; pfam02685
933093001063	glucokinase, proteobacterial type; Region: glk; TIGR00749
933093001064	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
933093001065	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
933093001066	active site
933093001067	intersubunit interface [polypeptide binding]; other site
933093001068	catalytic residue [active]
933093001069	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
933093001070	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093001071	putative substrate translocation pore; other site
933093001072	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093001073	Glycosyl hydrolases family 15; Region: Glyco_hydro_15; pfam00723
933093001074	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
933093001075	salt bridge; other site
933093001076	non-specific DNA binding site [nucleotide binding]; other site
933093001077	sequence-specific DNA binding site [nucleotide binding]; other site
933093001078	Protein of unknown function (DUF2975); Region: DUF2975; pfam11188
933093001079	ferrochelatase; Reviewed; Region: hemH; PRK00035
933093001080	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
933093001081	active site
933093001082	C-terminal domain interface [polypeptide binding]; other site
933093001083	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
933093001084	active site
933093001085	N-terminal domain interface [polypeptide binding]; other site
933093001086	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
933093001087	DNA-binding site [nucleotide binding]; DNA binding site
933093001088	RNA-binding motif; other site
933093001089	HIT family: HIT (Histidine triad) proteins, named for a motif related to the sequence HxHxH/Qxx (x, a hydrophobic amino acid), are a superfamily of nucleotide hydrolases and transferases, which act on the alpha-phosphate of ribonucleotides. On the basis...; Region: HIT_like; cl00228
933093001090	HIT family signature motif; other site
933093001091	catalytic residue [active]
933093001092	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
933093001093	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
933093001094	active site
933093001095	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
933093001096	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
933093001097	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
933093001098	HlyD family secretion protein; Region: HlyD_3; pfam13437
933093001099	Predicted membrane protein [Function unknown]; Region: COG1289
933093001100	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
933093001101	Predicted transcriptional regulators [Transcription]; Region: COG1733
933093001102	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
933093001103	Uncharacterized conserved protein [Function unknown]; Region: COG4278
933093001104	Methyltransferase domain; Region: Methyltransf_23; pfam13489
933093001105	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
933093001106	S-adenosylmethionine binding site [chemical binding]; other site
933093001107	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
933093001108	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
933093001109	Protein of unknown function (DUF3773); Region: DUF3773; pfam12608
933093001110	Dot/Icm secretion system protein (dot_icm_IcmQ); Region: Dot_icm_IcmQ; pfam09475
933093001111	TraM recognition site of TraD and TraG; Region: TraG-D_C; cl17375
933093001112	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
933093001113	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
933093001114	ligand binding site [chemical binding]; other site
933093001115	Macrophage killing protein with similarity to conjugation protein; Region: IcmL; pfam11393
933093001116	Protein of unknown function (DUF3625); Region: DUF3625; pfam12293
933093001117	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
933093001118	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
933093001119	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
933093001120	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
933093001121	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
933093001122	Bacterial conjugation TrbI-like protein; Region: TrbI; cl04242
933093001123	HNH nucleases; Region: HNHc; smart00507
933093001124	AAA-like domain; Region: AAA_10; pfam12846
933093001125	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093001126	metabolite-proton symporter; Region: 2A0106; TIGR00883
933093001127	putative substrate translocation pore; other site
933093001128	type VI secretion protein IcmF; Region: VI_IcmF; TIGR03348
933093001129	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
933093001130	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
933093001131	type IV / VI secretion system protein, DotU family; Region: IV_VI_DotU; TIGR03349
933093001132	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
933093001133	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
933093001134	purine monophosphate binding site [chemical binding]; other site
933093001135	dimer interface [polypeptide binding]; other site
933093001136	putative catalytic residues [active]
933093001137	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
933093001138	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
933093001139	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
933093001140	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
933093001141	S-adenosylmethionine binding site [chemical binding]; other site
933093001142	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
933093001143	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
933093001144	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
933093001145	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
933093001146	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
933093001147	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
933093001148	carboxyltransferase (CT) interaction site; other site
933093001149	biotinylation site [posttranslational modification]; other site
933093001150	Dehydroquinase class II; Region: DHquinase_II; pfam01220
933093001151	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
933093001152	trimer interface [polypeptide binding]; other site
933093001153	active site
933093001154	dimer interface [polypeptide binding]; other site
933093001155	pyruvate carboxylase subunit B; Provisional; Region: PRK14042
933093001156	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
933093001157	active site
933093001158	catalytic residues [active]
933093001159	metal binding site [ion binding]; metal-binding site
933093001160	homodimer binding site [polypeptide binding]; other site
933093001161	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
933093001162	carboxyltransferase (CT) interaction site; other site
933093001163	biotinylation site [posttranslational modification]; other site
933093001164	Zinc metalloprotease (elastase) [Amino acid transport and metabolism]; Region: LasB; COG3227
933093001165	Fungalysin/Thermolysin Propeptide Motif; Region: FTP; pfam07504
933093001166	Peptidase M4 family includes thermolysin, protealysin, aureolysin and neutral protease; Region: M4_neutral_protease; cd09597
933093001167	active site
933093001168	Zn binding site [ion binding]; other site
933093001169	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
933093001170	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
933093001171	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
933093001172	putative catalytic site [active]
933093001173	putative metal binding site [ion binding]; other site
933093001174	putative phosphate binding site [ion binding]; other site
933093001175	Fructose-1,6-bisphosphate aldolase; Region: FBP_aldolase_I_a; cd00948
933093001176	active site
933093001177	intersubunit interface [polypeptide binding]; other site
933093001178	catalytic residue [active]
933093001179	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
933093001180	ferredoxin-NADP reductase; Provisional; Region: PRK10926
933093001181	FAD binding pocket [chemical binding]; other site
933093001182	FAD binding motif [chemical binding]; other site
933093001183	phosphate binding motif [ion binding]; other site
933093001184	beta-alpha-beta structure motif; other site
933093001185	NAD binding pocket [chemical binding]; other site
933093001186	Protein of unknown function (DUF3579); Region: DUF3579; pfam12112
933093001187	Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183
933093001188	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
933093001189	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
933093001190	dimerization domain swap beta strand [polypeptide binding]; other site
933093001191	regulatory protein interface [polypeptide binding]; other site
933093001192	active site
933093001193	regulatory phosphorylation site [posttranslational modification]; other site
933093001194	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
933093001195	30S subunit binding site; other site
933093001196	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
933093001197	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
933093001198	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
933093001199	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
933093001200	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
933093001201	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
933093001202	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
933093001203	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
933093001204	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
933093001205	oligomer interface [polypeptide binding]; other site
933093001206	active site
933093001207	metal binding site [ion binding]; metal-binding site
933093001208	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
933093001209	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
933093001210	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
933093001211	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
933093001212	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
933093001213	HflK protein; Region: hflK; TIGR01933
933093001214	FtsH protease regulator HflC; Provisional; Region: PRK11029
933093001215	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
933093001216	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
933093001217	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
933093001218	GDP-binding site [chemical binding]; other site
933093001219	ACT binding site; other site
933093001220	IMP binding site; other site
933093001221	Predicted metal-dependent enzyme of the double-stranded beta helix superfamily [General function prediction only]; Region: COG5553
933093001222	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
933093001223	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
933093001224	GIY-YIG domain of uncharacterized hypothetical protein found in bacteria; Region: GIY-YIG_unchar_3; cd10448
933093001225	GIY-YIG motif/motif A; other site
933093001226	putative active site [active]
933093001227	putative metal binding site [ion binding]; other site
933093001228	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
933093001229	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
933093001230	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
933093001231	substrate binding pocket [chemical binding]; other site
933093001232	membrane-bound complex binding site; other site
933093001233	hinge residues; other site
933093001234	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
933093001235	dimer interface [polypeptide binding]; other site
933093001236	conserved gate region; other site
933093001237	putative PBP binding loops; other site
933093001238	ABC-ATPase subunit interface; other site
933093001239	glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493
933093001240	ATP-binding cassette domain of the binding protein-dependent transport systems; Region: ABC_Class3; cd03229
933093001241	Walker A/P-loop; other site
933093001242	ATP binding site [chemical binding]; other site
933093001243	Q-loop/lid; other site
933093001244	ABC transporter signature motif; other site
933093001245	Walker B; other site
933093001246	D-loop; other site
933093001247	H-loop/switch region; other site
933093001248	argininosuccinate synthase; Provisional; Region: PRK13820
933093001249	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
933093001250	ANP binding site [chemical binding]; other site
933093001251	Substrate Binding Site II [chemical binding]; other site
933093001252	Substrate Binding Site I [chemical binding]; other site
933093001253	Lyase; Region: Lyase_1; pfam00206
933093001254	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
933093001255	active sites [active]
933093001256	tetramer interface [polypeptide binding]; other site
933093001257	ornithine carbamoyltransferase; Provisional; Region: PRK00779
933093001258	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
933093001259	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
933093001260	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
933093001261	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
933093001262	active site
933093001263	Periplasmic binding protein; Region: Peripla_BP_6; pfam13458
933093001264	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
933093001265	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
933093001266	C-terminal peptidase (prc); Region: prc; TIGR00225
933093001267	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
933093001268	protein binding site [polypeptide binding]; other site
933093001269	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
933093001270	Catalytic dyad [active]
933093001271	Membrane-bound metallopeptidase [Cell division and chromosome partitioning]; Region: COG4942
933093001272	TATA element modulatory factor 1 TATA binding; Region: TMF_TATA_bd; pfam12325
933093001273	Peptidase family M23; Region: Peptidase_M23; pfam01551
933093001274	phosphoglyceromutase; Provisional; Region: PRK05434
933093001275	Phosphoglyceromutase [Carbohydrate transport and metabolism]; Region: GpmI; COG0696
933093001276	undecaprenyl pyrophosphate synthase; Provisional; Region: PRK14836
933093001277	Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255
933093001278	catalytic residue [active]
933093001279	putative FPP diphosphate  binding site; other site
933093001280	putative FPP binding hydrophobic cleft; other site
933093001281	dimer interface [polypeptide binding]; other site
933093001282	putative IPP diphosphate binding site; other site
933093001283	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
933093001284	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
933093001285	zinc metallopeptidase RseP; Provisional; Region: PRK10779
933093001286	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
933093001287	active site
933093001288	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
933093001289	protein binding site [polypeptide binding]; other site
933093001290	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
933093001291	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
933093001292	putative substrate binding region [chemical binding]; other site
933093001293	outer membrane protein assembly complex, YaeT protein; Region: OM_YaeT; TIGR03303
933093001294	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
933093001295	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
933093001296	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
933093001297	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
933093001298	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
933093001299	Surface antigen; Region: Bac_surface_Ag; pfam01103
933093001300	periplasmic chaperone; Provisional; Region: PRK10780
933093001301	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
933093001302	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
933093001303	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
933093001304	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
933093001305	trimer interface [polypeptide binding]; other site
933093001306	active site
933093001307	UDP-GlcNAc binding site [chemical binding]; other site
933093001308	lipid binding site [chemical binding]; lipid-binding site
933093001309	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
933093001310	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK12461
933093001311	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
933093001312	active site
933093001313	camphor resistance protein CrcB; Provisional; Region: PRK14217
933093001314	seryl-tRNA synthetase; Provisional; Region: PRK05431
933093001315	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
933093001316	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
933093001317	dimer interface [polypeptide binding]; other site
933093001318	active site
933093001319	motif 1; other site
933093001320	motif 2; other site
933093001321	motif 3; other site
933093001322	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
933093001323	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
933093001324	Uncharacterized protein family (UPF0157); Region: UPF0157; pfam04229
933093001325	Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; pfam05721
933093001326	Methyltransferase domain; Region: Methyltransf_23; pfam13489
933093001327	Methyltransferase domain; Region: Methyltransf_12; pfam08242
933093001328	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
933093001329	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
933093001330	active site
933093001331	catalytic tetrad [active]
933093001332	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
933093001333	S-adenosylmethionine binding site [chemical binding]; other site
933093001334	Methyltransferase domain; Region: Methyltransf_23; pfam13489
933093001335	hypothetical protein; Provisional; Region: PRK08233
933093001336	AAA domain; Region: AAA_18; pfam13238
933093001337	active site
933093001338	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
933093001339	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
933093001340	Coenzyme A binding pocket [chemical binding]; other site
933093001341	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
933093001342	RDD family; Region: RDD; pfam06271
933093001343	Predicted signal transduction protein containing EAL and modified HD-GYP domains [Signal transduction mechanisms]; Region: COG3434
933093001344	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
933093001345	Iron-sulfur protein interface; other site
933093001346	proximal quinone binding site [chemical binding]; other site
933093001347	SdhD (CybS) interface [polypeptide binding]; other site
933093001348	proximal heme binding site [chemical binding]; other site
933093001349	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
933093001350	SdhC subunit interface [polypeptide binding]; other site
933093001351	proximal heme binding site [chemical binding]; other site
933093001352	cardiolipin binding site; other site
933093001353	Iron-sulfur protein interface; other site
933093001354	proximal quinone binding site [chemical binding]; other site
933093001355	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
933093001356	L-aspartate oxidase; Provisional; Region: PRK06175
933093001357	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
933093001358	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
933093001359	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
933093001360	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
933093001361	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
933093001362	TPP-binding site [chemical binding]; other site
933093001363	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
933093001364	dimer interface [polypeptide binding]; other site
933093001365	PYR/PP interface [polypeptide binding]; other site
933093001366	TPP binding site [chemical binding]; other site
933093001367	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
933093001368	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
933093001369	E3 interaction surface; other site
933093001370	lipoyl attachment site [posttranslational modification]; other site
933093001371	e3 binding domain; Region: E3_binding; pfam02817
933093001372	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
933093001373	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
933093001374	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
933093001375	CoA-ligase; Region: Ligase_CoA; pfam00549
933093001376	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
933093001377	CoA binding domain; Region: CoA_binding; smart00881
933093001378	CoA-ligase; Region: Ligase_CoA; pfam00549
933093001379	pyridoxamine-phosphate oxidase; Region: pdxH; TIGR00558
933093001380	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
933093001381	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
933093001382	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093001383	D-galactonate transporter; Region: 2A0114; TIGR00893
933093001384	putative substrate translocation pore; other site
933093001385	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
933093001386	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
933093001387	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
933093001388	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
933093001389	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
933093001390	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
933093001391	active site
933093001392	potential protein location (hypothetical protein lp12_0551 [Legionella pneumophila subsp. pneumophila ATCC 43290]) that overlaps RNA (tRNA-Q)
933093001393	outer membrane lipoprotein LolB; Provisional; Region: lolB; PRK00022
933093001394	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
933093001395	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
933093001396	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
933093001397	active site
933093001398	(T/H)XGH motif; other site
933093001399	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
933093001400	Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019
933093001401	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
933093001402	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
933093001403	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
933093001404	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
933093001405	ligand binding site [chemical binding]; other site
933093001406	1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018
933093001407	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
933093001408	putative acyl-acceptor binding pocket; other site
933093001409	Small Multidrug Resistance protein; Region: Multi_Drug_Res; cl00910
933093001410	Uncharacterized bacterial proteins with similarity to Aminoglycoside 3'-phosphotransferase (APH) and Choline kinase (ChoK) family members. The APH/ChoK subfamily is part of a larger superfamily that includes the catalytic domains of other kinases; Region: APH_ChoK_like_1; cd05155
933093001411	Phosphotransferase enzyme family; Region: APH; pfam01636
933093001412	putative active site [active]
933093001413	putative substrate binding site [chemical binding]; other site
933093001414	ATP binding site [chemical binding]; other site
933093001415	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
933093001416	active site
933093001417	DNA polymerase IV; Validated; Region: PRK02406
933093001418	DNA binding site [nucleotide binding]
933093001419	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
933093001420	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
933093001421	DNA binding site [nucleotide binding]
933093001422	catalytic residue [active]
933093001423	H2TH interface [polypeptide binding]; other site
933093001424	putative catalytic residues [active]
933093001425	turnover-facilitating residue; other site
933093001426	intercalation triad [nucleotide binding]; other site
933093001427	8OG recognition residue [nucleotide binding]; other site
933093001428	putative reading head residues; other site
933093001429	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
933093001430	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
933093001431	The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide...; Region: Delta9-FADS-like; cd03505
933093001432	Fatty acid desaturase; Region: FA_desaturase; pfam00487
933093001433	Di-iron ligands [ion binding]; other site
933093001434	Transposase; Region: DDE_Tnp_ISL3; pfam01610
933093001435	acetoacetyl-CoA reductase; Region: AcAcCoA_reduct; TIGR01829
933093001436	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
933093001437	NAD(P) binding site [chemical binding]; other site
933093001438	active site
933093001439	acetoacetyl-CoA reductase; Region: AcAcCoA_reduct; TIGR01829
933093001440	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
933093001441	NAD(P) binding site [chemical binding]; other site
933093001442	active site
933093001443	PHB/PHA accumulation regulator DNA-binding domain; Region: PHB_acc_N; pfam07879
933093001444	Phasin protein; Region: Phasin_2; cl11491
933093001445	Protein of unknown function (DUF1460); Region: DUF1460; pfam07313
933093001446	Uncharacterized membrane protein, required for spore maturation in B.subtilis. [General function prediction only]; Region: SpmA; COG2715
933093001447	Uncharacterized membrane protein [Function unknown]; Region: SpmB; COG0700
933093001448	putative peptidase; Provisional; Region: PRK11649
933093001449	Peptidase family M23; Region: Peptidase_M23; pfam01551
933093001450	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
933093001451	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
933093001452	active site
933093001453	HIGH motif; other site
933093001454	dimer interface [polypeptide binding]; other site
933093001455	KMSKS motif; other site
933093001456	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
933093001457	RNA binding surface [nucleotide binding]; other site
933093001458	potential protein location (hypothetical protein lp12_0578 [Legionella pneumophila subsp. pneumophila ATCC 43290]) that overlaps RNA (23S ribosomal RNA)
933093001459	potential protein location (hypothetical protein lp12_0579 [Legionella pneumophila subsp. pneumophila ATCC 43290]) that overlaps RNA (23S ribosomal RNA)
933093001460	potential protein location (hypothetical protein lp12_0580 [Legionella pneumophila subsp. pneumophila ATCC 43290]) that overlaps RNA (23S ribosomal RNA)
933093001461	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
933093001462	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
933093001463	trimer interface [polypeptide binding]; other site
933093001464	putative metal binding site [ion binding]; other site
933093001465	glutathione reductase; Validated; Region: PRK06116
933093001466	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
933093001467	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
933093001468	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
933093001469	potential protein location (hypothetical protein) that overlaps protein (glutathione reductase)
933093001470	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
933093001471	adenosine deaminase; Provisional; Region: PRK09358
933093001472	active site
933093001473	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
933093001474	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
933093001475	Phosphate transport regulator (distant homolog of PhoU) [Inorganic ion transport and metabolism]; Region: COG1392
933093001476	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
933093001477	hypothetical protein; Validated; Region: PRK00228
933093001478	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
933093001479	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
933093001480	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
933093001481	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
933093001482	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
933093001483	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
933093001484	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
933093001485	Walker A motif; other site
933093001486	ATP binding site [chemical binding]; other site
933093001487	Walker B motif; other site
933093001488	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
933093001489	Membrane fusogenic activity; Region: BMFP; pfam04380
933093001490	Nitrogen regulatory protein PII [Amino acid transport and metabolism]; Region: GlnK; COG0347
933093001491	Nitrogen regulatory protein P-II; Region: P-II; smart00938
933093001492	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
933093001493	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
933093001494	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
933093001495	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
933093001496	pyridoxal 5'-phosphate binding site [chemical binding]; other site
933093001497	catalytic residue [active]
933093001498	Uncharacterized conserved protein [Function unknown]; Region: COG0398
933093001499	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
933093001500	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
933093001501	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
933093001502	putative acyl-acceptor binding pocket; other site
933093001503	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
933093001504	acyl-activating enzyme (AAE) consensus motif; other site
933093001505	AMP binding site [chemical binding]; other site
933093001506	active site
933093001507	CoA binding site [chemical binding]; other site
933093001508	Protein of unknown function (DUF1499); Region: DUF1499; pfam07386
933093001509	poly(R)-hydroxyalkanoic acid synthase, class I; Region: PHA_synth_I; TIGR01838
933093001510	Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus; Region: PhaC_N; pfam07167
933093001511	FeS assembly SUF system regulator, gammaproteobacterial; Region: suf_reg_Xantho; TIGR02944
933093001512	Transcriptional regulator; Region: Rrf2; pfam02082
933093001513	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
933093001514	putative ABC transporter; Region: ycf24; CHL00085
933093001515	FeS assembly ATPase SufC; Region: sufC; TIGR01978
933093001516	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
933093001517	Walker A/P-loop; other site
933093001518	ATP binding site [chemical binding]; other site
933093001519	Q-loop/lid; other site
933093001520	ABC transporter signature motif; other site
933093001521	Walker B; other site
933093001522	D-loop; other site
933093001523	H-loop/switch region; other site
933093001524	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814; cl03223
933093001525	FeS assembly protein SufD; Region: sufD; TIGR01981
933093001526	Uncharacterized protein family (UPF0051); Region: UPF0051; pfam01458
933093001527	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
933093001528	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
933093001529	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
933093001530	catalytic residue [active]
933093001531	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
933093001532	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
933093001533	trimerization site [polypeptide binding]; other site
933093001534	active site
933093001535	FeS assembly SUF system protein; Region: SUF_assoc; TIGR02945
933093001536	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
933093001537	EF-P lysine aminoacylase GenX; Region: genX; TIGR00462
933093001538	motif 1; other site
933093001539	dimer interface [polypeptide binding]; other site
933093001540	active site
933093001541	motif 2; other site
933093001542	motif 3; other site
933093001543	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
933093001544	S-adenosylmethionine binding site [chemical binding]; other site
933093001545	Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain [General function prediction only]; Region: COG2872
933093001546	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
933093001547	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093001548	putative substrate translocation pore; other site
933093001549	Major Facilitator Superfamily; Region: MFS_1; pfam07690
933093001550	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
933093001551	Domain of unknown function DUF21; Region: DUF21; pfam01595
933093001552	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
933093001553	Transporter associated domain; Region: CorC_HlyC; smart01091
933093001554	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
933093001555	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
933093001556	putative NAD(P) binding site [chemical binding]; other site
933093001557	putative substrate binding site [chemical binding]; other site
933093001558	catalytic Zn binding site [ion binding]; other site
933093001559	structural Zn binding site [ion binding]; other site
933093001560	dimer interface [polypeptide binding]; other site
933093001561	Domain of unknown function (DUF4332); Region: DUF4332; pfam14229
933093001562	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
933093001563	active site
933093001564	catalytic residues [active]
933093001565	metal binding site [ion binding]; metal-binding site
933093001566	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
933093001567	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
933093001568	gamma-glutamyl:cysteine ligase; Provisional; Region: PRK13516
933093001569	carboxylate-amine ligase, YbdK family; Region: gshA_cyan_rel; TIGR02050
933093001570	CoA binding domain; Region: CoA_binding_2; pfam13380
933093001571	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
933093001572	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
933093001573	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
933093001574	Legionella pneumophila major outer membrane protein precursor; Region: Legionella_OMP; pfam05150
933093001575	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
933093001576	Protein of unknown function (DUF1810); Region: DUF1810; cl02370
933093001577	Cupin domain; Region: Cupin_2; cl17218
933093001578	StaR_like; a well-conserved protein found in bacteria, plants, and animals. A family member from Streptomyces toyocaensis, StaR is part of a gene cluster involved in the biosynthesis of glycopeptide antibiotics (GPAs), specifically A47934. It has been...; Region: StaR_like; cd05804
933093001579	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
933093001580	DNA internalization-related competence protein ComEC/Rec2; Region: ComEC_Rec2; TIGR00361
933093001581	Competence protein; Region: Competence; pfam03772
933093001582	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
933093001583	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
933093001584	Tfp pilus assembly protein PilE [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilE; COG4968
933093001585	Neisseria PilC beta-propeller domain; Region: Neisseria_PilC; pfam05567
933093001586	Tfp pilus assembly protein PilX [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilX; COG4726
933093001587	PilX N-terminal; Region: PilX_N; pfam14341
933093001588	Tfp pilus assembly protein PilW [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilW; COG4966
933093001589	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
933093001590	type IV pilus modification protein PilV; Region: type_IV_pilV; TIGR02523
933093001591	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830
933093001592	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830
933093001593	Type II transport protein GspH; Region: GspH; pfam12019
933093001594	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
933093001595	Catalytic NodB homology domain of uncharacterized bacterial polysaccharide deacetylases; Region: CE4_NodB_like_1; cd10960
933093001596	NodB motif; other site
933093001597	putative active site [active]
933093001598	putative catalytic site [active]
933093001599	putative Zn binding site [ion binding]; other site
933093001600	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
933093001601	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
933093001602	thymidine kinase; Provisional; Region: PRK04296
933093001603	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093001604	Major Facilitator Superfamily; Region: MFS_1; pfam07690
933093001605	putative substrate translocation pore; other site
933093001606	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093001607	putative substrate translocation pore; other site
933093001608	D-galactonate transporter; Region: 2A0114; TIGR00893
933093001609	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
933093001610	phosphopentomutase; Provisional; Region: PRK05362
933093001611	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
933093001612	active site
933093001613	HslU subunit interaction site [polypeptide binding]; other site
933093001614	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
933093001615	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
933093001616	Walker A motif; other site
933093001617	ATP binding site [chemical binding]; other site
933093001618	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
933093001619	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
933093001620	Virulence factor BrkB; Region: Virul_fac_BrkB; cl07918
933093001621	T1SS-143 repeat domain; Region: T1SS_rpt_143; TIGR03660
933093001622	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
933093001623	metal ion-dependent adhesion site (MIDAS); other site
933093001624	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
933093001625	type I secretion C-terminal target domain (VC_A0849 subclass); Region: T1SS_VCA0849; TIGR03661
933093001626	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
933093001627	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
933093001628	Domain of unknown function, appears to be related to a diverse group of endonucleases; Region: Endonuclease_DUF559; cd01038
933093001629	putative active site [active]
933093001630	Neisseria meningitides Nape-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Nape_like_AP-endo; cd10281
933093001631	putative active site [active]
933093001632	putative catalytic site [active]
933093001633	putative DNA binding site [nucleotide binding]; other site
933093001634	putative phosphate binding site [ion binding]; other site
933093001635	metal binding site A [ion binding]; metal-binding site
933093001636	putative AP binding site [nucleotide binding]; other site
933093001637	putative metal binding site B [ion binding]; other site
933093001638	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
933093001639	putative catalytic site [active]
933093001640	putative phosphate binding site [ion binding]; other site
933093001641	active site
933093001642	metal binding site A [ion binding]; metal-binding site
933093001643	DNA binding site [nucleotide binding]
933093001644	putative AP binding site [nucleotide binding]; other site
933093001645	putative metal binding site B [ion binding]; other site
933093001646	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
933093001647	Malic enzyme, N-terminal domain; Region: malic; pfam00390
933093001648	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
933093001649	putative NAD(P) binding site [chemical binding]; other site
933093001650	D-galactonate transporter; Region: 2A0114; TIGR00893
933093001651	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093001652	putative substrate translocation pore; other site
933093001653	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093001654	putative substrate translocation pore; other site
933093001655	Major Facilitator Superfamily; Region: MFS_1; pfam07690
933093001656	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
933093001657	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
933093001658	aromatic amino acid transport protein; Region: araaP; TIGR00837
933093001659	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
933093001660	aromatic amino acid transport protein; Region: araaP; TIGR00837
933093001661	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
933093001662	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
933093001663	ligand binding site [chemical binding]; other site
933093001664	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
933093001665	ABC exporter membrane fusion protein, DevB family; Region: heterocyst_DevB; TIGR02971
933093001666	HlyD family secretion protein; Region: HlyD_3; pfam13437
933093001667	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
933093001668	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
933093001669	Walker A/P-loop; other site
933093001670	ATP binding site [chemical binding]; other site
933093001671	Q-loop/lid; other site
933093001672	ABC transporter signature motif; other site
933093001673	Walker B; other site
933093001674	D-loop; other site
933093001675	H-loop/switch region; other site
933093001676	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
933093001677	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
933093001678	Walker A/P-loop; other site
933093001679	ATP binding site [chemical binding]; other site
933093001680	Q-loop/lid; other site
933093001681	ABC transporter signature motif; other site
933093001682	Walker B; other site
933093001683	D-loop; other site
933093001684	H-loop/switch region; other site
933093001685	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
933093001686	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
933093001687	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
933093001688	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
933093001689	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
933093001690	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
933093001691	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
933093001692	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
933093001693	N-acetyl-D-glucosamine binding site [chemical binding]; other site
933093001694	catalytic residue [active]
933093001695	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
933093001696	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
933093001697	substrate binding site [chemical binding]; other site
933093001698	hexamer interface [polypeptide binding]; other site
933093001699	metal binding site [ion binding]; metal-binding site
933093001700	DoxX; Region: DoxX; pfam07681
933093001701	Uncharacterized protein conserved in bacteria (DUF2063); Region: DUF2063; cl01262
933093001702	hypothetical protein; Provisional; Region: PRK05409
933093001703	Predicted integral membrane protein (DUF2282); Region: DUF2282; pfam10048
933093001704	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
933093001705	Hypothetical patatin similar to Z1214 protein of Escherichia coli; Region: Pat_hypo_Ecoli_Z1214_like; cd07209
933093001706	nucleophile elbow; other site
933093001707	DoxX; Region: DoxX; pfam07681
933093001708	Predicted membrane protein [Function unknown]; Region: COG2259
933093001709	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
933093001710	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
933093001711	acetoacetate decarboxylase; Provisional; Region: PRK02265
933093001712	Predicted integral membrane protein (DUF2282); Region: DUF2282; pfam10048
933093001713	Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]; Region: CyaA; COG2114
933093001714	cyclase homology domain; Region: CHD; cd07302
933093001715	nucleotidyl binding site; other site
933093001716	metal binding site [ion binding]; metal-binding site
933093001717	dimer interface [polypeptide binding]; other site
933093001718	Uncharacterized protein conserved in bacteria (DUF2063); Region: DUF2063; pfam09836
933093001719	hypothetical protein; Provisional; Region: PRK05409
933093001720	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
933093001721	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
933093001722	substrate binding pocket [chemical binding]; other site
933093001723	membrane-bound complex binding site; other site
933093001724	hinge residues; other site
933093001725	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
933093001726	metal binding triad; other site
933093001727	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
933093001728	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
933093001729	metal binding triad; other site
933093001730	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
933093001731	HlyD family secretion protein; Region: HlyD_3; pfam13437
933093001732	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
933093001733	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
933093001734	Walker A/P-loop; other site
933093001735	ATP binding site [chemical binding]; other site
933093001736	Q-loop/lid; other site
933093001737	ABC transporter signature motif; other site
933093001738	Walker B; other site
933093001739	D-loop; other site
933093001740	H-loop/switch region; other site
933093001741	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
933093001742	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
933093001743	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
933093001744	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
933093001745	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
933093001746	FeS/SAM binding site; other site
933093001747	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
933093001748	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
933093001749	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
933093001750	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
933093001751	DsbD alpha interface [polypeptide binding]; other site
933093001752	catalytic residues [active]
933093001753	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
933093001754	oligomerisation interface [polypeptide binding]; other site
933093001755	mobile loop; other site
933093001756	roof hairpin; other site
933093001757	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
933093001758	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
933093001759	ring oligomerisation interface [polypeptide binding]; other site
933093001760	ATP/Mg binding site [chemical binding]; other site
933093001761	stacking interactions; other site
933093001762	hinge regions; other site
933093001763	Ferritin-like domain; Region: Ferritin; pfam00210
933093001764	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
933093001765	dimerization interface [polypeptide binding]; other site
933093001766	DPS ferroxidase diiron center [ion binding]; other site
933093001767	ion pore; other site
933093001768	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
933093001769	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
933093001770	DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559
933093001771	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
933093001772	Mg2+ binding site [ion binding]; other site
933093001773	G-X-G motif; other site
933093001774	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
933093001775	anchoring element; other site
933093001776	dimer interface [polypeptide binding]; other site
933093001777	ATP binding site [chemical binding]; other site
933093001778	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
933093001779	active site
933093001780	metal binding site [ion binding]; metal-binding site
933093001781	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
933093001782	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
933093001783	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
933093001784	Walker A/P-loop; other site
933093001785	ATP binding site [chemical binding]; other site
933093001786	Q-loop/lid; other site
933093001787	ABC transporter signature motif; other site
933093001788	Walker B; other site
933093001789	D-loop; other site
933093001790	H-loop/switch region; other site
933093001791	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
933093001792	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
933093001793	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
933093001794	Walker A/P-loop; other site
933093001795	ATP binding site [chemical binding]; other site
933093001796	Q-loop/lid; other site
933093001797	ABC transporter signature motif; other site
933093001798	Walker B; other site
933093001799	D-loop; other site
933093001800	H-loop/switch region; other site
933093001801	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
933093001802	prolyl-tRNA synthetase; Provisional; Region: PRK09194
933093001803	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
933093001804	dimer interface [polypeptide binding]; other site
933093001805	motif 1; other site
933093001806	active site
933093001807	motif 2; other site
933093001808	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
933093001809	putative deacylase active site [active]
933093001810	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
933093001811	active site
933093001812	motif 3; other site
933093001813	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
933093001814	anticodon binding site; other site
933093001815	FOG: Ankyrin repeat [General function prediction only]; Region: Arp; COG0666
933093001816	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
933093001817	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
933093001818	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
933093001819	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
933093001820	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
933093001821	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
933093001822	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
933093001823	Sulfate transporter family; Region: Sulfate_transp; pfam00916
933093001824	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeC; cd03378
933093001825	active site clefts [active]
933093001826	zinc binding site [ion binding]; other site
933093001827	dimer interface [polypeptide binding]; other site
933093001828	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
933093001829	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
933093001830	Ligand Binding Site [chemical binding]; other site
933093001831	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
933093001832	Protein-L-isoaspartate carboxylmethyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: Pcm; COG2518
933093001833	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
933093001834	S-adenosylmethionine binding site [chemical binding]; other site
933093001835	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
933093001836	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
933093001837	substrate-cofactor binding pocket; other site
933093001838	pyridoxal 5'-phosphate binding site [chemical binding]; other site
933093001839	catalytic residue [active]
933093001840	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
933093001841	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
933093001842	NAD(P) binding site [chemical binding]; other site
933093001843	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
933093001844	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
933093001845	Walker A/P-loop; other site
933093001846	ATP binding site [chemical binding]; other site
933093001847	Q-loop/lid; other site
933093001848	ABC transporter signature motif; other site
933093001849	Walker B; other site
933093001850	D-loop; other site
933093001851	H-loop/switch region; other site
933093001852	ABC transporter; Region: ABC_tran_2; pfam12848
933093001853	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
933093001854	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
933093001855	Domain of unknown function (DUF4341); Region: DUF4341; pfam14241
933093001856	Predicted transporter component [General function prediction only]; Region: COG2391
933093001857	Sulphur transport; Region: Sulf_transp; pfam04143
933093001858	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
933093001859	Macrophage killing protein with similarity to conjugation protein; Region: IcmL; pfam11393
933093001860	formimidoylglutamase; Provisional; Region: PRK13775
933093001861	Formimidoylglutamase or HutE; Region: Formimidoylglutamase; cd09988
933093001862	putative active site [active]
933093001863	putative metal binding site [ion binding]; other site
933093001864	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
933093001865	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
933093001866	NAD(P) binding site [chemical binding]; other site
933093001867	active site
933093001868	imidazolonepropionase; Validated; Region: PRK09356
933093001869	Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296
933093001870	active site
933093001871	Domain of unknown function (DUF4163); Region: DUF4163; pfam13739
933093001872	Protein of unknown function (DUF3298); Region: DUF3298; pfam11738
933093001873	Predicted membrane protein [Function unknown]; Region: COG1297
933093001874	putative oligopeptide transporter, OPT family; Region: TIGR00733
933093001875	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
933093001876	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
933093001877	dimer interface [polypeptide binding]; other site
933093001878	phosphorylation site [posttranslational modification]
933093001879	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
933093001880	ATP binding site [chemical binding]; other site
933093001881	Mg2+ binding site [ion binding]; other site
933093001882	G-X-G motif; other site
933093001883	heavy metal response regulator; Region: cztR_silR_copR; TIGR01387
933093001884	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
933093001885	active site
933093001886	phosphorylation site [posttranslational modification]
933093001887	intermolecular recognition site; other site
933093001888	dimerization interface [polypeptide binding]; other site
933093001889	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
933093001890	DNA binding site [nucleotide binding]
933093001891	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
933093001892	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
933093001893	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
933093001894	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
933093001895	HIGH motif; other site
933093001896	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
933093001897	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
933093001898	active site
933093001899	KMSKS motif; other site
933093001900	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
933093001901	tRNA binding surface [nucleotide binding]; other site
933093001902	anticodon binding site; other site
933093001903	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
933093001904	multidrug efflux protein; Reviewed; Region: PRK09579
933093001905	TcdA/TcdB pore forming domain; Region: TcdA_TcdB_pore; pfam12920
933093001906	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
933093001907	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
933093001908	HlyD family secretion protein; Region: HlyD_3; pfam13437
933093001909	BON domain; Region: BON; pfam04972
933093001910	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
933093001911	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
933093001912	dimer interface [polypeptide binding]; other site
933093001913	active site
933093001914	glycine-pyridoxal phosphate binding site [chemical binding]; other site
933093001915	folate binding site [chemical binding]; other site
933093001916	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
933093001917	ATP cone domain; Region: ATP-cone; pfam03477
933093001918	transcription antitermination factor NusB; Region: nusB; TIGR01951
933093001919	thiamine monophosphate kinase; Provisional; Region: PRK05731
933093001920	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
933093001921	ATP binding site [chemical binding]; other site
933093001922	dimerization interface [polypeptide binding]; other site
933093001923	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
933093001924	tetramer interfaces [polypeptide binding]; other site
933093001925	binuclear metal-binding site [ion binding]; other site
933093001926	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
933093001927	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
933093001928	NAD synthetase; Provisional; Region: PRK13981
933093001929	Glutamine aminotransferase (GAT, glutaminase) domain of glutamine-dependent NAD synthetases (class 7 and 8 nitrilases); Region: GAT_Gln-NAD-synth; cd07570
933093001930	multimer interface [polypeptide binding]; other site
933093001931	active site
933093001932	catalytic triad [active]
933093001933	protein interface 1 [polypeptide binding]; other site
933093001934	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
933093001935	homodimer interface [polypeptide binding]; other site
933093001936	NAD binding pocket [chemical binding]; other site
933093001937	ATP binding pocket [chemical binding]; other site
933093001938	Mg binding site [ion binding]; other site
933093001939	active-site loop [active]
933093001940	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
933093001941	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
933093001942	ATP binding site [chemical binding]; other site
933093001943	putative Mg++ binding site [ion binding]; other site
933093001944	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
933093001945	nucleotide binding region [chemical binding]; other site
933093001946	ATP-binding site [chemical binding]; other site
933093001947	Uncharacterized protein conserved in bacteria (DUF2147); Region: DUF2147; pfam09917
933093001948	replicative DNA helicase; Region: DnaB; TIGR00665
933093001949	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
933093001950	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
933093001951	Walker A motif; other site
933093001952	ATP binding site [chemical binding]; other site
933093001953	Walker B motif; other site
933093001954	DNA binding loops [nucleotide binding]
933093001955	alanine racemase; Reviewed; Region: alr; PRK00053
933093001956	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
933093001957	active site
933093001958	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
933093001959	substrate binding site [chemical binding]; other site
933093001960	catalytic residues [active]
933093001961	dimer interface [polypeptide binding]; other site
933093001962	Surface antigen [Cell envelope biogenesis, outer membrane]; Region: LipA; COG4520
933093001963	FOG: CBS domain [General function prediction only]; Region: COG0517
933093001964	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_10; cd04623
933093001965	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
933093001966	Iron-binding zinc finger CDGSH type; Region: zf-CDGSH; pfam09360
933093001967	Iron-binding zinc finger CDGSH type; Region: zf-CDGSH; pfam09360
933093001968	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
933093001969	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
933093001970	metal binding site [ion binding]; metal-binding site
933093001971	active site
933093001972	I-site; other site
933093001973	lipoyl synthase; Provisional; Region: PRK05481
933093001974	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
933093001975	FeS/SAM binding site; other site
933093001976	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
933093001977	GIY-YIG motif/motif A; other site
933093001978	putative active site [active]
933093001979	putative metal binding site [ion binding]; other site
933093001980	POT family; Region: PTR2; cl17359
933093001981	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
933093001982	Methyltransferase domain; Region: Methyltransf_11; pfam08241
933093001983	S-adenosylmethionine binding site [chemical binding]; other site
933093001984	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_III; cd01996
933093001985	Ligand Binding Site [chemical binding]; other site
933093001986	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
933093001987	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
933093001988	substrate binding site [chemical binding]; other site
933093001989	glutamase interaction surface [polypeptide binding]; other site
933093001990	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13146
933093001991	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
933093001992	putative active site [active]
933093001993	oxyanion strand; other site
933093001994	catalytic triad [active]
933093001995	CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513
933093001996	ligand binding site; other site
933093001997	tetramer interface; other site
933093001998	N-acetylneuraminate synthase; Region: NeuB_NnaB; TIGR03569
933093001999	NeuB family; Region: NeuB; pfam03102
933093002000	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
933093002001	NeuB binding interface [polypeptide binding]; other site
933093002002	putative substrate binding site [chemical binding]; other site
933093002003	UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing; Region: NeuC_NnaA; TIGR03568
933093002004	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
933093002005	active site
933093002006	homodimer interface [polypeptide binding]; other site
933093002007	Putative Acyltransferase (AT), Left-handed parallel beta-Helix (LbH) domain; This group is composed of mostly uncharacterized proteins containing an N-terminal helical subdomain followed by a LbH domain. The alignment contains 6 turns, each containing...; Region: LbH_AT_putative; cd03360
933093002008	sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; Region: NeuD_NnaD; TIGR03570
933093002009	putative trimer interface [polypeptide binding]; other site
933093002010	putative CoA binding site [chemical binding]; other site
933093002011	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain associated with the NTP (Nucleotidyl transferase) domain downstream. CBS is a small domain originally identified in cystathionine beta-synthase and subsequently...; Region: CBS_pair_NTP_transferase_assoc; cd04607
933093002012	aminotransferase, LLPSF_NHT_00031 family; Region: NHT_00031; TIGR04181
933093002013	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
933093002014	inhibitor-cofactor binding pocket; inhibition site
933093002015	pyridoxal 5'-phosphate binding site [chemical binding]; other site
933093002016	catalytic residue [active]
933093002017	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
933093002018	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
933093002019	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
933093002020	Walker A/P-loop; other site
933093002021	ATP binding site [chemical binding]; other site
933093002022	Q-loop/lid; other site
933093002023	ABC transporter signature motif; other site
933093002024	Walker B; other site
933093002025	D-loop; other site
933093002026	H-loop/switch region; other site
933093002027	C-Terminal domain of O-antigenic polysaccharide transporter protein Wzt and related proteins; Region: Wzt_C-like; cd10147
933093002028	putative carbohydrate binding site [chemical binding]; other site
933093002029	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; cl17405
933093002030	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
933093002031	RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321
933093002032	NADP binding site [chemical binding]; other site
933093002033	active site
933093002034	putative substrate binding site [chemical binding]; other site
933093002035	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
933093002036	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
933093002037	NAD binding site [chemical binding]; other site
933093002038	substrate binding site [chemical binding]; other site
933093002039	homodimer interface [polypeptide binding]; other site
933093002040	active site
933093002041	Periplasmic copper-binding protein (NosD); Region: NosD; pfam05048
933093002042	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
933093002043	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
933093002044	active site
933093002045	dimer interface [polypeptide binding]; other site
933093002046	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
933093002047	dimer interface [polypeptide binding]; other site
933093002048	active site
933093002049	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
933093002050	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
933093002051	substrate binding site; other site
933093002052	tetramer interface; other site
933093002053	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
933093002054	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
933093002055	NAD(P) binding site [chemical binding]; other site
933093002056	active site
933093002057	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
933093002058	The members of this subfamily catalyze the formation of a phosphodiester bond between a membrane-associated undecaprenyl-phosphate (Und-P) molecule and N-acetylhexosamine 1-phosphate, which is usually donated by a soluble UDP-N-acetylhexosamine precursor; Region: GT_WbpL_WbcO_like; cd06854
933093002059	Mg++ binding site [ion binding]; other site
933093002060	putative catalytic motif [active]
933093002061	putative substrate binding site [chemical binding]; other site
933093002062	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
933093002063	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
933093002064	catalytic triad [active]
933093002065	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
933093002066	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
933093002067	pseudaminic acid biosynthesis-associated protein PseG; Region: PseG; TIGR03590
933093002068	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
933093002069	glutamate-1-semialdehyde 2,1-aminomutase; Provisional; Region: PRK06209
933093002070	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
933093002071	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
933093002072	catalytic residue [active]
933093002073	SpsF is a glycosyltrnasferase implicated in the synthesis of the spore coat; Region: GT2_SpsF; cd02518
933093002074	ligand binding site; other site
933093002075	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
933093002076	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
933093002077	imidazole glycerol phosphate synthase subunit HisF; Provisional; Region: PRK01033
933093002078	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
933093002079	substrate binding site [chemical binding]; other site
933093002080	glutamase interaction surface [polypeptide binding]; other site
933093002081	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13141
933093002082	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
933093002083	putative active site [active]
933093002084	oxyanion strand; other site
933093002085	catalytic triad [active]
933093002086	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_III; cd01996
933093002087	Ligand Binding Site [chemical binding]; other site
933093002088	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
933093002089	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
933093002090	active site
933093002091	catalytic tetrad [active]
933093002092	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
933093002093	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
933093002094	inhibitor-cofactor binding pocket; inhibition site
933093002095	pyridoxal 5'-phosphate binding site [chemical binding]; other site
933093002096	catalytic residue [active]
933093002097	UDP-N-acetylglucosamine 4,6-dehydratase; Region: PseB; TIGR03589
933093002098	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
933093002099	NAD(P) binding site [chemical binding]; other site
933093002100	homodimer interface [polypeptide binding]; other site
933093002101	substrate binding site [chemical binding]; other site
933093002102	active site
933093002103	pseudaminic acid synthase; Region: PseI; TIGR03586
933093002104	NeuB family; Region: NeuB; pfam03102
933093002105	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
933093002106	NeuB binding interface [polypeptide binding]; other site
933093002107	putative substrate binding site [chemical binding]; other site
933093002108	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
933093002109	M28 Zn-Peptidases; Region: M28_like_3; cd05644
933093002110	Domain of unknown function (DUF2172); Region: DUF2172; pfam09940
933093002111	active site
933093002112	metal binding site [ion binding]; metal-binding site
933093002113	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
933093002114	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
933093002115	Probable Catalytic site; other site
933093002116	metal-binding site
933093002117	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
933093002118	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
933093002119	Probable Catalytic site; other site
933093002120	metal-binding site
933093002121	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
933093002122	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
933093002123	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
933093002124	carbon storage regulator; Provisional; Region: PRK01712
933093002125	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
933093002126	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
933093002127	Biotin operon repressor [Transcription]; Region: BirA; COG1654
933093002128	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
933093002129	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
933093002130	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
933093002131	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
933093002132	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
933093002133	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
933093002134	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
933093002135	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
933093002136	Ligand Binding Site [chemical binding]; other site
933093002137	TilS substrate binding domain; Region: TilS; pfam09179
933093002138	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
933093002139	Transposase IS200 like; Region: Y1_Tnp; cl00848
933093002140	GDSL-like Lipase/Acylhydrolase family; Region: Lipase_GDSL_2; pfam13472
933093002141	GDSL-like Lipase/Acylhydrolase family; Region: Lipase_GDSL_2; pfam13472
933093002142	catalytic triad [active]
933093002143	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
933093002144	DRTGG domain; Region: DRTGG; pfam07085
933093002145	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; Region: Glyphos_transf; pfam04464
933093002146	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
933093002147	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
933093002148	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
933093002149	FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545
933093002150	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
933093002151	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
933093002152	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093002153	muropeptide transporter; Reviewed; Region: ampG; PRK11902
933093002154	putative substrate translocation pore; other site
933093002155	Protein of unknown function (DUF3757); Region: DUF3757; pfam12582
933093002156	Quinolinate synthetase A protein; Region: NadA; pfam02445
933093002157	L-aspartate oxidase; Provisional; Region: PRK09077
933093002158	L-aspartate oxidase; Provisional; Region: PRK06175
933093002159	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
933093002160	adenylosuccinate lyase; Provisional; Region: PRK09285
933093002161	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
933093002162	tetramer interface [polypeptide binding]; other site
933093002163	active site
933093002164	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
933093002165	putative transporter; Provisional; Region: PRK11660
933093002166	Sulfate transporter family; Region: Sulfate_transp; pfam00916
933093002167	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
933093002168	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
933093002169	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
933093002170	active site
933093002171	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
933093002172	Linear amide C-N hydrolases, choloylglycine hydrolase family; Region: CBAH; pfam02275
933093002173	active site
933093002174	phosphoenolpyruvate synthase; Validated; Region: PRK06464
933093002175	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
933093002176	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
933093002177	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
933093002178	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
933093002179	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
933093002180	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
933093002181	Nicotinate-nucleotide pyrophosphorylase [Coenzyme metabolism]; Region: NadC; COG0157
933093002182	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
933093002183	dimerization interface [polypeptide binding]; other site
933093002184	active site
933093002185	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Reviewed; Region: PRK12446
933093002186	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
933093002187	active site
933093002188	homodimer interface [polypeptide binding]; other site
933093002189	hypothetical protein; Provisional; Region: PRK08201
933093002190	Uncharacterized M20 Dipeptidases; Region: M20_dipept_like_5; cd05682
933093002191	metal binding site [ion binding]; metal-binding site
933093002192	putative dimer interface [polypeptide binding]; other site
933093002193	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
933093002194	rod shape-determining protein MreB; Provisional; Region: PRK13927
933093002195	MreB and similar proteins; Region: MreB_like; cd10225
933093002196	nucleotide binding site [chemical binding]; other site
933093002197	Mg binding site [ion binding]; other site
933093002198	putative protofilament interaction site [polypeptide binding]; other site
933093002199	RodZ interaction site [polypeptide binding]; other site
933093002200	rod shape-determining protein MreC; Provisional; Region: PRK13922
933093002201	rod shape-determining protein MreC; Region: MreC; pfam04085
933093002202	rod shape-determining protein MreD; Region: shape_MreD; TIGR03426
933093002203	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
933093002204	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
933093002205	active site
933093002206	isocitrate dehydrogenase; Validated; Region: PRK07362
933093002207	isocitrate dehydrogenase; Reviewed; Region: PRK07006
933093002208	Uncharacterized conserved protein [Function unknown]; Region: COG2127
933093002209	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
933093002210	Clp amino terminal domain; Region: Clp_N; pfam02861
933093002211	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
933093002212	Walker A motif; other site
933093002213	ATP binding site [chemical binding]; other site
933093002214	Walker B motif; other site
933093002215	arginine finger; other site
933093002216	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
933093002217	Walker A motif; other site
933093002218	ATP binding site [chemical binding]; other site
933093002219	Walker B motif; other site
933093002220	arginine finger; other site
933093002221	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
933093002222	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
933093002223	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
933093002224	putative metal binding site; other site
933093002225	Rhomboid family; Region: Rhomboid; cl11446
933093002226	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
933093002227	Peptidase family M23; Region: Peptidase_M23; pfam01551
933093002228	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
933093002229	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
933093002230	generic binding surface II; other site
933093002231	generic binding surface I; other site
933093002232	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
933093002233	Sporulation related domain; Region: SPOR; pfam05036
933093002234	Bacterial transglutaminase-like cysteine proteinase BTLCP; Region: BTLCP; cl17596
933093002235	biofilm formation regulator HmsP; Provisional; Region: PRK11829
933093002236	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
933093002237	dimerization interface [polypeptide binding]; other site
933093002238	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
933093002239	metal binding site [ion binding]; metal-binding site
933093002240	active site
933093002241	I-site; other site
933093002242	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
933093002243	Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319
933093002244	putative bacillithiol system oxidoreductase, YpdA family; Region: Bthiol_YpdA; TIGR04018
933093002245	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_3; pfam13738
933093002246	Domain of unknown function (DUF4372); Region: DUF4372; pfam14294
933093002247	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
933093002248	classical (c) SDRs; Region: SDR_c; cd05233
933093002249	hypothetical protein; Provisional; Region: PRK06194
933093002250	NAD(P) binding site [chemical binding]; other site
933093002251	active site
933093002252	Vi polysaccharide biosynthesis protein TviB; Provisional; Region: PRK15182
933093002253	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
933093002254	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
933093002255	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
933093002256	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
933093002257	NAD(P) binding site [chemical binding]; other site
933093002258	active site
933093002259	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
933093002260	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
933093002261	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
933093002262	binding surface
933093002263	Tetratricopeptide repeat; Region: TPR_16; pfam13432
933093002264	TPR motif; other site
933093002265	Tetratricopeptide repeat; Region: TPR_16; pfam13432
933093002266	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
933093002267	binding surface
933093002268	TPR motif; other site
933093002269	HEAT repeats; Region: HEAT_2; pfam13646
933093002270	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
933093002271	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
933093002272	DXD motif; other site
933093002273	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
933093002274	active site
933093002275	ribulose/triose binding site [chemical binding]; other site
933093002276	phosphate binding site [ion binding]; other site
933093002277	substrate (anthranilate) binding pocket [chemical binding]; other site
933093002278	product (indole) binding pocket [chemical binding]; other site
933093002279	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
933093002280	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
933093002281	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
933093002282	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
933093002283	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
933093002284	glutamine binding [chemical binding]; other site
933093002285	catalytic triad [active]
933093002286	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
933093002287	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
933093002288	Walker A/P-loop; other site
933093002289	ATP binding site [chemical binding]; other site
933093002290	Q-loop/lid; other site
933093002291	ABC transporter signature motif; other site
933093002292	Walker B; other site
933093002293	D-loop; other site
933093002294	H-loop/switch region; other site
933093002295	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
933093002296	OstA-like protein; Region: OstA; pfam03968
933093002297	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3117; cl01200
933093002298	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
933093002299	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
933093002300	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
933093002301	active site
933093002302	motif I; other site
933093002303	motif II; other site
933093002304	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
933093002305	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
933093002306	putative active site [active]
933093002307	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
933093002308	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
933093002309	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
933093002310	Walker A/P-loop; other site
933093002311	ATP binding site [chemical binding]; other site
933093002312	Q-loop/lid; other site
933093002313	ABC transporter signature motif; other site
933093002314	Walker B; other site
933093002315	D-loop; other site
933093002316	H-loop/switch region; other site
933093002317	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
933093002318	Permease; Region: Permease; cl00510
933093002319	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
933093002320	mce related protein; Region: MCE; pfam02470
933093002321	Toluene tolerance, Ttg2; Region: Tol_Tol_Ttg2; pfam05494
933093002322	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
933093002323	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
933093002324	anti sigma factor interaction site; other site
933093002325	regulatory phosphorylation site [posttranslational modification]; other site
933093002326	BolA-like protein; Region: BolA; cl00386
933093002327	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
933093002328	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
933093002329	hinge; other site
933093002330	active site
933093002331	Uncharacterized conserved protein [Function unknown]; Region: COG0327
933093002332	NIF3 (NGG1p interacting factor 3); Region: NIF3; cl15371
933093002333	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
933093002334	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
933093002335	Walker A/P-loop; other site
933093002336	ATP binding site [chemical binding]; other site
933093002337	Q-loop/lid; other site
933093002338	ABC transporter signature motif; other site
933093002339	Walker B; other site
933093002340	D-loop; other site
933093002341	H-loop/switch region; other site
933093002342	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
933093002343	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
933093002344	FtsX-like permease family; Region: FtsX; pfam02687
933093002345	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
933093002346	HlyD family secretion protein; Region: HlyD_3; pfam13437
933093002347	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
933093002348	Flagellar regulatory protein FleQ; Region: FleQ; pfam06490
933093002349	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
933093002350	Walker A motif; other site
933093002351	ATP binding site [chemical binding]; other site
933093002352	Walker B motif; other site
933093002353	arginine finger; other site
933093002354	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
933093002355	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
933093002356	putative inner membrane peptidase; Provisional; Region: PRK11778
933093002357	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
933093002358	tandem repeat interface [polypeptide binding]; other site
933093002359	oligomer interface [polypeptide binding]; other site
933093002360	active site residues [active]
933093002361	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13540
933093002362	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
933093002363	Walker A/P-loop; other site
933093002364	ATP binding site [chemical binding]; other site
933093002365	Q-loop/lid; other site
933093002366	ABC transporter signature motif; other site
933093002367	Walker B; other site
933093002368	D-loop; other site
933093002369	H-loop/switch region; other site
933093002370	CcmB protein; Region: CcmB; cl17444
933093002371	Cytochrome C assembly protein; Region: Cytochrom_C_asm; cl00504
933093002372	heme exporter protein CcmD; Region: cytochro_ccmD; TIGR03141
933093002373	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13254
933093002374	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: CcmF; COG1138
933093002375	periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily; Region: dsbE; TIGR00385
933093002376	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
933093002377	catalytic residues [active]
933093002378	central insert; other site
933093002379	Cytochrome C biogenesis protein; Region: CcmH; pfam03918
933093002380	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
933093002381	binding surface
933093002382	TPR motif; other site
933093002383	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
933093002384	Alkyladenine DNA glycosylase catalyzes the first step in base excision repair; Region: AAG; cd00540
933093002385	active site
933093002386	DNA binding site [nucleotide binding]
933093002387	Superfamily II DNA helicase [DNA replication, recombination, and repair]; Region: RecQ; COG0514
933093002388	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
933093002389	ATP binding site [chemical binding]; other site
933093002390	putative Mg++ binding site [ion binding]; other site
933093002391	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
933093002392	nucleotide binding region [chemical binding]; other site
933093002393	ATP-binding site [chemical binding]; other site
933093002394	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
933093002395	HRDC domain; Region: HRDC; pfam00570
933093002396	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
933093002397	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
933093002398	active site
933093002399	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
933093002400	3-hydroxybutyryl-CoA dehydratase; Validated; Region: PRK05809
933093002401	substrate binding site [chemical binding]; other site
933093002402	oxyanion hole (OAH) forming residues; other site
933093002403	trimer interface [polypeptide binding]; other site
933093002404	3-hydroxyisobutyryl-CoA hydrolase; Provisional; Region: PRK05617
933093002405	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
933093002406	substrate binding site [chemical binding]; other site
933093002407	oxyanion hole (OAH) forming residues; other site
933093002408	trimer interface [polypeptide binding]; other site
933093002409	2-enoyl-CoA Hydratase C-terminal region; Region: ECH_C; pfam13766
933093002410	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
933093002411	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
933093002412	G1 box; other site
933093002413	putative GEF interaction site [polypeptide binding]; other site
933093002414	GTP/Mg2+ binding site [chemical binding]; other site
933093002415	Switch I region; other site
933093002416	G2 box; other site
933093002417	G3 box; other site
933093002418	Switch II region; other site
933093002419	G4 box; other site
933093002420	G5 box; other site
933093002421	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
933093002422	NAD/NADP transhydrogenase beta subunit [Energy production and conversion]; Region: PntB; COG1282
933093002423	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
933093002424	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
933093002425	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
933093002426	NAD/NADP transhydrogenase alpha subunit [Energy production and conversion]; Region: PntA; COG3288
933093002427	ligand binding site [chemical binding]; other site
933093002428	homodimer interface [polypeptide binding]; other site
933093002429	NAD(P) binding site [chemical binding]; other site
933093002430	trimer interface B [polypeptide binding]; other site
933093002431	trimer interface A [polypeptide binding]; other site
933093002432	Uncharacterized protein with SCP/PR1 domains [Function unknown]; Region: COG2340
933093002433	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
933093002434	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
933093002435	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
933093002436	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
933093002437	metal binding site [ion binding]; metal-binding site
933093002438	active site
933093002439	I-site; other site
933093002440	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
933093002441	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
933093002442	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
933093002443	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
933093002444	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
933093002445	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
933093002446	metal binding site [ion binding]; metal-binding site
933093002447	dimer interface [polypeptide binding]; other site
933093002448	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
933093002449	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
933093002450	trimer interface [polypeptide binding]; other site
933093002451	active site
933093002452	substrate binding site [chemical binding]; other site
933093002453	CoA binding site [chemical binding]; other site
933093002454	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
933093002455	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Region: LPLAT_LCLAT1-like; cd07990
933093002456	putative acyl-acceptor binding pocket; other site
933093002457	Cys/Met metabolism PLP-dependent enzyme; Region: Cys_Met_Meta_PP; pfam01053
933093002458	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
933093002459	homodimer interface [polypeptide binding]; other site
933093002460	substrate-cofactor binding pocket; other site
933093002461	pyridoxal 5'-phosphate binding site [chemical binding]; other site
933093002462	catalytic residue [active]
933093002463	PAS fold; Region: PAS_7; pfam12860
933093002464	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
933093002465	PAS domain; Region: PAS_9; pfam13426
933093002466	putative active site [active]
933093002467	heme pocket [chemical binding]; other site
933093002468	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
933093002469	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
933093002470	metal binding site [ion binding]; metal-binding site
933093002471	active site
933093002472	I-site; other site
933093002473	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
933093002474	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion]; Region: UbiH; COG0654
933093002475	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
933093002476	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
933093002477	FAD binding domain; Region: FAD_binding_4; pfam01565
933093002478	Cytokinin dehydrogenase 1, FAD and cytokinin binding; Region: Cytokin-bind; pfam09265
933093002479	Type IV pilus biogenesis; Region: Pilus_PilP; pfam11356
933093002480	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
933093002481	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
933093002482	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
933093002483	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
933093002484	A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; Region: MutY; COG1194
933093002485	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
933093002486	minor groove reading motif; other site
933093002487	helix-hairpin-helix signature motif; other site
933093002488	substrate binding pocket [chemical binding]; other site
933093002489	active site
933093002490	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; cl15304
933093002491	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
933093002492	DNA binding and oxoG recognition site [nucleotide binding]
933093002493	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
933093002494	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
933093002495	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
933093002496	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
933093002497	protein binding site [polypeptide binding]; other site
933093002498	Isochorismatase family; Region: Isochorismatase; pfam00857
933093002499	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
933093002500	catalytic triad [active]
933093002501	dimer interface [polypeptide binding]; other site
933093002502	conserved cis-peptide bond; other site
933093002503	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK08217
933093002504	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
933093002505	NAD(P) binding site [chemical binding]; other site
933093002506	active site
933093002507	FlgN protein; Region: FlgN; pfam05130
933093002508	flagellar biosynthesis anti-sigma factor FlgM; Region: FlgM_jcvi; TIGR03824
933093002509	SAF-like; Region: SAF_2; pfam13144
933093002510	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
933093002511	Cytochrome c5 [Energy production and conversion]; Region: CycB; COG3245
933093002512	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
933093002513	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
933093002514	nucleotide binding site [chemical binding]; other site
933093002515	Type III pantothenate kinase; Region: Pan_kinase; cl17198
933093002516	cell division protein MraZ; Reviewed; Region: PRK00326
933093002517	MraZ protein; Region: MraZ; pfam02381
933093002518	MraZ protein; Region: MraZ; pfam02381
933093002519	MraW methylase family; Region: Methyltransf_5; cl17771
933093002520	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
933093002521	Cell division protein FtsL; Region: FtsL; pfam04999
933093002522	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
933093002523	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
933093002524	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
933093002525	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
933093002526	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
933093002527	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
933093002528	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
933093002529	erythronate-4-phosphate dehydrogenase; Validated; Region: PRK00257
933093002530	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
933093002531	ligand binding site [chemical binding]; other site
933093002532	NAD binding site [chemical binding]; other site
933093002533	catalytic site [active]
933093002534	homodimer interface [polypeptide binding]; other site
933093002535	Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_1; cd06158
933093002536	Peptidase family M50; Region: Peptidase_M50; pfam02163
933093002537	active site
933093002538	putative substrate binding region [chemical binding]; other site
933093002539	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
933093002540	PAP2_like proteins, Lipid A 1-phosphatase subfamily. Lipid A 1-phosphatase, or LpxE from Francisella novicida selectively dephosphorylates lipid A at the 1-position. Lipid A is the membrane-anchor component of lipopolysaccharides (LPS), the major...; Region: PAP2_lipid_A_1_phosphatase; cd03389
933093002541	active site
933093002542	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
933093002543	Ligand binding site [chemical binding]; other site
933093002544	Electron transfer flavoprotein domain; Region: ETF; pfam01012
933093002545	electron transfer flavoprotein subunit alpha; Provisional; Region: PLN00022
933093002546	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
933093002547	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
933093002548	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
933093002549	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
933093002550	hexamer interface [polypeptide binding]; other site
933093002551	ligand binding site [chemical binding]; other site
933093002552	putative active site [active]
933093002553	NAD(P) binding site [chemical binding]; other site
933093002554	Membrane carboxypeptidase/penicillin-binding protein [Cell envelope biogenesis, outer membrane]; Region: MrcA; COG5009
933093002555	Transglycosylase; Region: Transgly; pfam00912
933093002556	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
933093002557	Cell division protein FtsA; Region: FtsA; cl17206
933093002558	Competence protein A; Region: Competence_A; pfam11104
933093002559	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
933093002560	Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilN; COG3166
933093002561	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
933093002562	Pilus assembly protein, PilO; Region: PilO; pfam04350
933093002563	Tfp pilus assembly protein PilP [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilP; COG3168
933093002564	Pilus assembly protein, PilP; Region: PilP; pfam04351
933093002565	AMIN domain; Region: AMIN; pfam11741
933093002566	type IV pilus secretin (or competence protein) PilQ; Region: IV_pilus_PilQ; TIGR02515
933093002567	Secretin and TonB N terminus short domain; Region: STN; smart00965
933093002568	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
933093002569	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
933093002570	shikimate kinase; Reviewed; Region: aroK; PRK00131
933093002571	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
933093002572	ADP binding site [chemical binding]; other site
933093002573	magnesium binding site [ion binding]; other site
933093002574	putative shikimate binding site; other site
933093002575	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
933093002576	active site
933093002577	dimer interface [polypeptide binding]; other site
933093002578	metal binding site [ion binding]; metal-binding site
933093002579	AAA domain; Region: AAA_22; pfam13401
933093002580	Sporulation related domain; Region: SPOR; pfam05036
933093002581	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
933093002582	Ligand Binding Site [chemical binding]; other site
933093002583	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
933093002584	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
933093002585	active site
933093002586	Riboflavin kinase; Region: Flavokinase; smart00904
933093002587	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
933093002588	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
933093002589	active site
933093002590	HIGH motif; other site
933093002591	nucleotide binding site [chemical binding]; other site
933093002592	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
933093002593	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
933093002594	active site
933093002595	KMSKS motif; other site
933093002596	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
933093002597	tRNA binding surface [nucleotide binding]; other site
933093002598	anticodon binding site; other site
933093002599	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
933093002600	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
933093002601	Class I aldolases; Region: Aldolase_Class_I; cl17187
933093002602	catalytic residue [active]
933093002603	GTPase Era; Reviewed; Region: era; PRK00089
933093002604	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
933093002605	G1 box; other site
933093002606	GTP/Mg2+ binding site [chemical binding]; other site
933093002607	Switch I region; other site
933093002608	G2 box; other site
933093002609	Switch II region; other site
933093002610	G3 box; other site
933093002611	G4 box; other site
933093002612	G5 box; other site
933093002613	KH domain; Region: KH_2; pfam07650
933093002614	Recombination protein O N terminal; Region: RecO_N; pfam11967
933093002615	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
933093002616	Recombination protein O C terminal; Region: RecO_C; pfam02565
933093002617	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
933093002618	Leucine-rich repeats; other site
933093002619	Substrate binding site [chemical binding]; other site
933093002620	Leucine rich repeat; Region: LRR_8; pfam13855
933093002621	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
933093002622	active site
933093002623	hydrophilic channel; other site
933093002624	dimerization interface [polypeptide binding]; other site
933093002625	catalytic residues [active]
933093002626	active site lid [active]
933093002627	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
933093002628	2-oxoacid:acceptor oxidoreductase, alpha subunit; Region: OAFO_sf; TIGR03710
933093002629	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
933093002630	dimer interface [polypeptide binding]; other site
933093002631	PYR/PP interface [polypeptide binding]; other site
933093002632	TPP binding site [chemical binding]; other site
933093002633	substrate binding site [chemical binding]; other site
933093002634	2-oxoglutarate ferredoxin oxidoreductase subunit beta; Reviewed; Region: PRK11867
933093002635	Thiamine pyrophosphate (TPP family), 2-oxoglutarate ferredoxin oxidoreductase (OGFOR) subfamily, TPP-binding module; OGFOR catalyzes the oxidative decarboxylation of 2-oxo-acids, with ferredoxin acting as an electron acceptor. In the TCA cycle, OGFOR...; Region: TPP_OGFOR; cd03375
933093002636	TPP-binding site [chemical binding]; other site
933093002637	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
933093002638	YccA-like proteins; Region: YccA_like; cd10433
933093002639	Nit1, Nit 2, and related proteins, and the Nit1-like domain of NitFhit (class 10 nitrilases); Region: nit; cd07572
933093002640	nitrilase; Region: PLN02798
933093002641	putative active site [active]
933093002642	catalytic triad [active]
933093002643	dimer interface [polypeptide binding]; other site
933093002644	protease TldD; Provisional; Region: tldD; PRK10735
933093002645	hypothetical protein; Provisional; Region: PRK10279
933093002646	Bacterial patatin-like phospholipase domain containing protein 6; Region: Pat_NTE_like_bacteria; cd07228
933093002647	active site
933093002648	nucleophile elbow; other site
933093002649	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
933093002650	Bacterial long-chain fatty acid CoA synthetase (LC-FACS), including Marinobacter hydrocarbonoclasticus isoprenoid Coenzyme A synthetase; Region: LC_FACS_bac; cd05932
933093002651	acyl-activating enzyme (AAE) consensus motif; other site
933093002652	putative AMP binding site [chemical binding]; other site
933093002653	putative active site [active]
933093002654	putative CoA binding site [chemical binding]; other site
933093002655	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
933093002656	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
933093002657	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
933093002658	ATP binding site [chemical binding]; other site
933093002659	putative Mg++ binding site [ion binding]; other site
933093002660	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
933093002661	nucleotide binding region [chemical binding]; other site
933093002662	ATP-binding site [chemical binding]; other site
933093002663	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
933093002664	RmuC family; Region: RmuC; pfam02646
933093002665	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
933093002666	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
933093002667	nucleotide binding pocket [chemical binding]; other site
933093002668	K-X-D-G motif; other site
933093002669	catalytic site [active]
933093002670	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
933093002671	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
933093002672	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
933093002673	Dimer interface [polypeptide binding]; other site
933093002674	BRCT sequence motif; other site
933093002675	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_18; cd08505
933093002676	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
933093002677	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
933093002678	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
933093002679	dimer interface [polypeptide binding]; other site
933093002680	conserved gate region; other site
933093002681	putative PBP binding loops; other site
933093002682	ABC-ATPase subunit interface; other site
933093002683	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
933093002684	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
933093002685	dimer interface [polypeptide binding]; other site
933093002686	conserved gate region; other site
933093002687	putative PBP binding loops; other site
933093002688	ABC-ATPase subunit interface; other site
933093002689	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
933093002690	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
933093002691	putative active site [active]
933093002692	putative PHP Thumb interface [polypeptide binding]; other site
933093002693	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
933093002694	generic binding surface II; other site
933093002695	generic binding surface I; other site
933093002696	phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase; Provisional; Region: PRK12324
933093002697	UbiA prenyltransferase family; Region: UbiA; pfam01040
933093002698	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
933093002699	Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG1086
933093002700	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
933093002701	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
933093002702	NAD(P) binding site [chemical binding]; other site
933093002703	homodimer interface [polypeptide binding]; other site
933093002704	substrate binding site [chemical binding]; other site
933093002705	active site
933093002706	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
933093002707	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
933093002708	nucleotide binding site [chemical binding]; other site
933093002709	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_3; pfam13640
933093002710	Uncharacterized ACR, COG2135; Region: DUF159; pfam02586
933093002711	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
933093002712	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
933093002713	Catalytic site [active]
933093002714	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
933093002715	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
933093002716	active site
933093002717	DNA binding site [nucleotide binding]
933093002718	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
933093002719	Antirestriction protein (ArdA); Region: ArdA; pfam07275
933093002720	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
933093002721	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
933093002722	dimer interface [polypeptide binding]; other site
933093002723	ssDNA binding site [nucleotide binding]; other site
933093002724	tetramer (dimer of dimers) interface [polypeptide binding]; other site
933093002725	Phage integrase, N-terminal; Region: Integrase_l_N; pfam12834
933093002726	Integrase; Region: Integrase_1; pfam12835
933093002727	Phage integrase, N-terminal; Region: Integrase_l_N; pfam12834
933093002728	TraM recognition site of TraD and TraG; Region: TraG-D_C; cl17375
933093002729	conjugative coupling factor TraD, SXT/TOL subfamily; Region: SXT_TraD; TIGR03743
933093002730	conjugative coupling factor TraD, TOL family; Region: conj_TOL_TraD; TIGR03754
933093002731	TraG-like protein, N-terminal region; Region: TraG_N; pfam07916
933093002732	integrating conjugative element protein, PFL_4711 family; Region: conj_TIGR03755
933093002733	integrating conjugative element protein, PFL_4710 family; Region: conj_TIGR03756
933093002734	conjugative transfer ATPase, PFL_4706 family; Region: traC_PFL_4706; TIGR03744
933093002735	F pilus assembly Type-IV secretion system for plasmid transfer; Region: TraC_F_IV; pfam11130
933093002736	Domain of unknown function DUF87; Region: DUF87; pfam01935
933093002737	conjugative transfer region lipoprotein, TIGR03751 family; Region: conj_TIGR03751
933093002738	integrating conjugative element protein, PFL_4705 family; Region: conj_TIGR03752
933093002739	basic region leucin zipper; Region: BRLZ; smart00338
933093002740	Protein of unknown function (DUF3438); Region: DUF3438; cl13372
933093002741	Protein of unknown function (DUF2895); Region: DUF2895; pfam11444
933093002742	conjugative transfer region protein, TIGR03750 family; Region: conj_TIGR03750
933093002743	Plasmid protein of unknown function (Plasmid_RAQPRD); Region: Plasmid_RAQPRD; pfam09686
933093002744	Domain of unknown function (DUF4400); Region: DUF4400; cl14023
933093002745	Protein of unknown function (DUF2859); Region: DUF2859; pfam11072
933093002746	integrating conjugative element protein, PFL_4693 family; Region: conj_TIGR03759
933093002747	conjugative transfer region protein, TIGR03748 family; Region: conj_PilL
933093002748	Global regulator protein family; Region: CsrA; pfam02599
933093002749	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
933093002750	non-specific DNA binding site [nucleotide binding]; other site
933093002751	salt bridge; other site
933093002752	sequence-specific DNA binding site [nucleotide binding]; other site
933093002753	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
933093002754	DNA-methyltransferase (dcm); Region: dcm; TIGR00675
933093002755	cofactor binding site; other site
933093002756	DNA binding site [nucleotide binding]
933093002757	substrate interaction site [chemical binding]; other site
933093002758	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
933093002759	additional DNA contacts [nucleotide binding]; other site
933093002760	mismatch recognition site; other site
933093002761	active site
933093002762	zinc binding site [ion binding]; other site
933093002763	DNA intercalation site [nucleotide binding]; other site
933093002764	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093002765	putative substrate translocation pore; other site
933093002766	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
933093002767	active site
933093002768	catalytic residues [active]
933093002769	metal binding site [ion binding]; metal-binding site
933093002770	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
933093002771	non-specific DNA binding site [nucleotide binding]; other site
933093002772	salt bridge; other site
933093002773	sequence-specific DNA binding site [nucleotide binding]; other site
933093002774	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; cl17523
933093002775	integrase; Provisional; Region: PRK09692
933093002776	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
933093002777	active site
933093002778	Int/Topo IB signature motif; other site
933093002779	Transposase; Region: DDE_Tnp_ISL3; pfam01610
933093002780	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
933093002781	Helix-turn-helix domain of transposase family ISL3; Region: HTH_Tnp_ISL3; pfam13542
933093002782	Transposase; Region: DDE_Tnp_ISL3; pfam01610
933093002783	Domain of unknown function (DUF4263); Region: DUF4263; pfam14082
933093002784	Domain of unknown function (DUF927); Region: DUF927; pfam06048
933093002785	Helix-turn-helix domain; Region: HTH_17; cl17695
933093002786	deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK05318
933093002787	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
933093002788	N-terminal domain of reverse transcriptase; Region: RVT_N; pfam13655
933093002789	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
933093002790	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
933093002791	putative active site [active]
933093002792	putative NTP binding site [chemical binding]; other site
933093002793	putative nucleic acid binding site [nucleotide binding]; other site
933093002794	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
933093002795	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
933093002796	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
933093002797	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
933093002798	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
933093002799	active site
933093002800	DNA binding site [nucleotide binding]
933093002801	Int/Topo IB signature motif; other site
933093002802	Transposase Tn5 dimerisation domain; Region: Dimer_Tnp_Tn5; pfam02281
933093002803	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
933093002804	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
933093002805	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
933093002806	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
933093002807	Coenzyme A binding pocket [chemical binding]; other site
933093002808	Uncharacterized protein family (UPF0157); Region: UPF0157; pfam04229
933093002809	Domain of unknown function (DUF4111); Region: DUF4111; pfam13427
933093002810	Methyltransferase domain; Region: Methyltransf_23; pfam13489
933093002811	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
933093002812	S-adenosylmethionine binding site [chemical binding]; other site
933093002813	Fic family protein [Function unknown]; Region: COG3177
933093002814	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
933093002815	Coenzyme A binding pocket [chemical binding]; other site
933093002816	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
933093002817	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
933093002818	motif II; other site
933093002819	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
933093002820	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
933093002821	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
933093002822	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
933093002823	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
933093002824	motif II; other site
933093002825	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
933093002826	Outer membrane efflux protein; Region: OEP; pfam02321
933093002827	Outer membrane efflux protein; Region: OEP; pfam02321
933093002828	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
933093002829	HlyD family secretion protein; Region: HlyD_3; pfam13437
933093002830	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
933093002831	Poly-beta-hydroxybutyrate polymerase N terminal; Region: PHBC_N; pfam12551
933093002832	poly(R)-hydroxyalkanoic acid synthase, class I; Region: PHA_synth_I; TIGR01838
933093002833	Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus; Region: PhaC_N; pfam07167
933093002834	Exopolysaccharide synthesis, ExoD; Region: ExoD; pfam06055
933093002835	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
933093002836	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
933093002837	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
933093002838	Phosphotransferase enzyme family; Region: APH; pfam01636
933093002839	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
933093002840	methionine sulfoxide reductase B; Provisional; Region: PRK00222
933093002841	SelR domain; Region: SelR; pfam01641
933093002842	EamA-like transporter family; Region: EamA; cl17759
933093002843	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
933093002844	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
933093002845	PAS domain; Region: PAS_9; pfam13426
933093002846	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
933093002847	PAS domain; Region: PAS_9; pfam13426
933093002848	putative active site [active]
933093002849	heme pocket [chemical binding]; other site
933093002850	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
933093002851	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
933093002852	metal binding site [ion binding]; metal-binding site
933093002853	active site
933093002854	I-site; other site
933093002855	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
933093002856	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
933093002857	KaiB-like family; composed of the circadian clock proteins, KaiB and the N-terminal KaiB-like sensory domain of SasA. KaiB is an essential protein in maintaining circadian rhythm. It was originally discovered from the cyanobacterium Synechococcus as part...; Region: KaiB_like; cd02978
933093002858	tetramer interface [polypeptide binding]; other site
933093002859	dimer interface [polypeptide binding]; other site
933093002860	circadian clock protein KaiC; Reviewed; Region: PRK09302
933093002861	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
933093002862	Walker A motif; other site
933093002863	ATP binding site [chemical binding]; other site
933093002864	Walker B motif; other site
933093002865	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
933093002866	Walker A motif; other site
933093002867	ATP binding site [chemical binding]; other site
933093002868	Walker B motif; other site
933093002869	Glycosyl hydrolases family 18; Region: Glyco_hydro_18; pfam00704
933093002870	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
933093002871	active site
933093002872	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
933093002873	Coenzyme A binding pocket [chemical binding]; other site
933093002874	Beta-lactamase; Region: Beta-lactamase; pfam00144
933093002875	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
933093002876	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
933093002877	catalytic core [active]
933093002878	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
933093002879	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
933093002880	N-acetyl-D-glucosamine binding site [chemical binding]; other site
933093002881	catalytic residue [active]
933093002882	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
933093002883	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
933093002884	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
933093002885	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
933093002886	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
933093002887	substrate binding pocket [chemical binding]; other site
933093002888	membrane-bound complex binding site; other site
933093002889	hinge residues; other site
933093002890	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
933093002891	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
933093002892	substrate binding pocket [chemical binding]; other site
933093002893	membrane-bound complex binding site; other site
933093002894	hinge residues; other site
933093002895	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
933093002896	Soluble P-type ATPase [General function prediction only]; Region: COG4087
933093002897	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
933093002898	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
933093002899	acyl-activating enzyme (AAE) consensus motif; other site
933093002900	AMP binding site [chemical binding]; other site
933093002901	active site
933093002902	CoA binding site [chemical binding]; other site
933093002903	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
933093002904	nucleoside/Zn binding site; other site
933093002905	dimer interface [polypeptide binding]; other site
933093002906	catalytic motif [active]
933093002907	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
933093002908	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
933093002909	dimerization interface [polypeptide binding]; other site
933093002910	Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]; Region: CyaA; COG2114
933093002911	cyclase homology domain; Region: CHD; cd07302
933093002912	nucleotidyl binding site; other site
933093002913	metal binding site [ion binding]; metal-binding site
933093002914	dimer interface [polypeptide binding]; other site
933093002915	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
933093002916	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
933093002917	S-adenosylmethionine binding site [chemical binding]; other site
933093002918	Nitronate monooxygenase; Region: NMO; pfam03060
933093002919	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
933093002920	FMN binding site [chemical binding]; other site
933093002921	substrate binding site [chemical binding]; other site
933093002922	putative catalytic residue [active]
933093002923	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
933093002924	COQ9; Region: COQ9; pfam08511
933093002925	Domain of unknown function (DUF4349); Region: DUF4349; pfam14257
933093002926	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
933093002927	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
933093002928	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
933093002929	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
933093002930	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
933093002931	dimer interface [polypeptide binding]; other site
933093002932	conserved gate region; other site
933093002933	putative PBP binding loops; other site
933093002934	ABC-ATPase subunit interface; other site
933093002935	putrescine/spermidine ABC transporter ATPase protein; Reviewed; Region: potA; PRK09452
933093002936	ATP-binding cassette domain of the polyamine transporter; Region: ABC_PotA_N; cd03300
933093002937	Walker A/P-loop; other site
933093002938	ATP binding site [chemical binding]; other site
933093002939	Q-loop/lid; other site
933093002940	ABC transporter signature motif; other site
933093002941	Walker B; other site
933093002942	D-loop; other site
933093002943	H-loop/switch region; other site
933093002944	TOBE domain; Region: TOBE_2; pfam08402
933093002945	GIY-YIG domain of uncharacterized hypothetical protein found in bacteria; Region: GIY-YIG_unchar_3; cd10448
933093002946	GIY-YIG motif/motif A; other site
933093002947	putative active site [active]
933093002948	putative metal binding site [ion binding]; other site
933093002949	short chain dehydrogenase; Provisional; Region: PRK08219
933093002950	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
933093002951	NADP binding site [chemical binding]; other site
933093002952	active site
933093002953	steroid binding site; other site
933093002954	Zn-dependent carboxypeptidase [Amino acid transport and metabolism]; Region: COG2317
933093002955	Peptidase family M32 includes thermostable carboxypeptidases TaqCP and PfuCP; Region: M32_Taq; cd06460
933093002956	active site
933093002957	Zn binding site [ion binding]; other site
933093002958	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
933093002959	Coenzyme A binding pocket [chemical binding]; other site
933093002960	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Ada; COG2169
933093002961	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
933093002962	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
933093002963	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
933093002964	DNA binding site [nucleotide binding]
933093002965	active site
933093002966	probable polyamine oxidase; Region: PLN02268
933093002967	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
933093002968	pyruvate decarboxylase; Region: PLN02573
933093002969	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
933093002970	dimer interface [polypeptide binding]; other site
933093002971	PYR/PP interface [polypeptide binding]; other site
933093002972	TPP binding site [chemical binding]; other site
933093002973	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
933093002974	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
933093002975	TPP-binding site [chemical binding]; other site
933093002976	dimer interface [polypeptide binding]; other site
933093002977	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
933093002978	Peptidase family M28; Region: Peptidase_M28; pfam04389
933093002979	metal binding site [ion binding]; metal-binding site
933093002980	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
933093002981	Putative serine esterase (DUF676); Region: DUF676; pfam05057
933093002982	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
933093002983	active site
933093002984	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093002985	metabolite-proton symporter; Region: 2A0106; TIGR00883
933093002986	putative substrate translocation pore; other site
933093002987	acetylornithine deacetylase; Provisional; Region: PRK07522
933093002988	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
933093002989	metal binding site [ion binding]; metal-binding site
933093002990	putative dimer interface [polypeptide binding]; other site
933093002991	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
933093002992	Sugar specificity; other site
933093002993	Pyrimidine base specificity; other site
933093002994	ATP-binding site [chemical binding]; other site
933093002995	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
933093002996	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
933093002997	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
933093002998	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
933093002999	metal binding site [ion binding]; metal-binding site
933093003000	active site
933093003001	I-site; other site
933093003002	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
933093003003	Memo (mediator of ErbB2-driven cell motility) is co-precipitated with the C terminus of ErbB2, a protein involved in cell motility; Region: MEMO_like; cd07361
933093003004	putative ligand binding pocket/active site [active]
933093003005	putative metal binding site [ion binding]; other site
933093003006	AmmeMemoRadiSam system protein A; Region: AmmeMemoSam_A; TIGR04335
933093003007	AMMECR1; Region: AMMECR1; pfam01871
933093003008	AmmeMemoRadiSam system radical SAM enzyme; Region: AmmeMemoSam_rS; TIGR04337
933093003009	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
933093003010	FeS/SAM binding site; other site
933093003011	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
933093003012	Sel1-like repeats; Region: SEL1; smart00671
933093003013	Sel1-like repeats; Region: SEL1; smart00671
933093003014	Sel1-like repeats; Region: SEL1; smart00671
933093003015	Sel1-like repeats; Region: SEL1; smart00671
933093003016	Sel1-like repeats; Region: SEL1; smart00671
933093003017	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
933093003018	Sel1-like repeats; Region: SEL1; smart00671
933093003019	Sel1-like repeats; Region: SEL1; smart00671
933093003020	Sel1-like repeats; Region: SEL1; smart00671
933093003021	Sel1-like repeats; Region: SEL1; smart00671
933093003022	Sel1-like repeats; Region: SEL1; smart00671
933093003023	Sel1-like repeats; Region: SEL1; smart00671
933093003024	Sel1-like repeats; Region: SEL1; smart00671
933093003025	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
933093003026	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
933093003027	dimer interface [polypeptide binding]; other site
933093003028	phosphorylation site [posttranslational modification]
933093003029	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
933093003030	ATP binding site [chemical binding]; other site
933093003031	Mg2+ binding site [ion binding]; other site
933093003032	G-X-G motif; other site
933093003033	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
933093003034	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
933093003035	active site
933093003036	phosphorylation site [posttranslational modification]
933093003037	intermolecular recognition site; other site
933093003038	dimerization interface [polypeptide binding]; other site
933093003039	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
933093003040	Walker A motif; other site
933093003041	ATP binding site [chemical binding]; other site
933093003042	Walker B motif; other site
933093003043	arginine finger; other site
933093003044	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
933093003045	AsnC family; Region: AsnC_trans_reg; pfam01037
933093003046	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
933093003047	Peptidase family M48; Region: Peptidase_M48; pfam01435
933093003048	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
933093003049	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
933093003050	catalytic motif [active]
933093003051	Zn binding site [ion binding]; other site
933093003052	RibD C-terminal domain; Region: RibD_C; cl17279
933093003053	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
933093003054	Lumazine binding domain; Region: Lum_binding; pfam00677
933093003055	Lumazine binding domain; Region: Lum_binding; pfam00677
933093003056	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09311
933093003057	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
933093003058	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
933093003059	dimerization interface [polypeptide binding]; other site
933093003060	active site
933093003061	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
933093003062	homopentamer interface [polypeptide binding]; other site
933093003063	active site
933093003064	CTP synthetase; Validated; Region: pyrG; PRK05380
933093003065	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
933093003066	Catalytic site [active]
933093003067	active site
933093003068	UTP binding site [chemical binding]; other site
933093003069	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
933093003070	active site
933093003071	putative oxyanion hole; other site
933093003072	catalytic triad [active]
933093003073	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
933093003074	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
933093003075	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
933093003076	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
933093003077	outer membrane assembly lipoprotein YfiO; Region: OM_YfiO; TIGR03302
933093003078	Putative exonuclease, RdgC; Region: RdgC; pfam04381
933093003079	K+ potassium transporter; Region: K_trans; pfam02705
933093003080	Putative MetA-pathway of phenol degradation; Region: Phenol_MetA_deg; cl01768
933093003081	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
933093003082	Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092
933093003083	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
933093003084	putative RNA binding site [nucleotide binding]; other site
933093003085	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
933093003086	S-adenosylmethionine binding site [chemical binding]; other site
933093003087	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
933093003088	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
933093003089	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
933093003090	Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_2; cd03139
933093003091	conserved cys residue [active]
933093003092	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
933093003093	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
933093003094	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
933093003095	metal binding site [ion binding]; metal-binding site
933093003096	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
933093003097	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
933093003098	substrate binding site [chemical binding]; other site
933093003099	glutamase interaction surface [polypeptide binding]; other site
933093003100	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
933093003101	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
933093003102	catalytic residues [active]
933093003103	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
933093003104	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
933093003105	putative active site [active]
933093003106	oxyanion strand; other site
933093003107	catalytic triad [active]
933093003108	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
933093003109	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
933093003110	active site
933093003111	motif I; other site
933093003112	motif II; other site
933093003113	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
933093003114	putative active site pocket [active]
933093003115	4-fold oligomerization interface [polypeptide binding]; other site
933093003116	metal binding residues [ion binding]; metal-binding site
933093003117	3-fold/trimer interface [polypeptide binding]; other site
933093003118	histidinol-phosphate aminotransferase; Region: hisC; TIGR01141
933093003119	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
933093003120	pyridoxal 5'-phosphate binding site [chemical binding]; other site
933093003121	homodimer interface [polypeptide binding]; other site
933093003122	catalytic residue [active]
933093003123	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
933093003124	histidinol dehydrogenase; Region: hisD; TIGR00069
933093003125	NAD binding site [chemical binding]; other site
933093003126	dimerization interface [polypeptide binding]; other site
933093003127	product binding site; other site
933093003128	substrate binding site [chemical binding]; other site
933093003129	zinc binding site [ion binding]; other site
933093003130	catalytic residues [active]
933093003131	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
933093003132	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
933093003133	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
933093003134	Trp repressor protein; Region: Trp_repressor; cl17266
933093003135	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
933093003136	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
933093003137	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
933093003138	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
933093003139	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
933093003140	active site
933093003141	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
933093003142	DNA-binding site [nucleotide binding]; DNA binding site
933093003143	RNA-binding motif; other site
933093003144	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
933093003145	30S subunit binding site; other site
933093003146	YbaK-like.  The YbaK family of deacylase domains includes the INS amino acid-editing domain of  the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting homologs, YbaK, ProX, and PrdX. The primary function of INS is to hydrolyze...; Region: YbaK_like; cd04332
933093003147	putative deacylase active site [active]
933093003148	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
933093003149	MarR family; Region: MarR_2; pfam12802
933093003150	MarR family; Region: MarR_2; cl17246
933093003151	Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384
933093003152	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
933093003153	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
933093003154	LysE type translocator; Region: LysE; cl00565
933093003155	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
933093003156	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
933093003157	Coenzyme A binding pocket [chemical binding]; other site
933093003158	Predicted ATPase [General function prediction only]; Region: COG3911
933093003159	AAA domain; Region: AAA_28; pfam13521
933093003160	Major Facilitator Superfamily; Region: MFS_1; pfam07690
933093003161	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
933093003162	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
933093003163	flagellar basal body rod protein FlgB; Provisional; Region: flgB; PRK12619
933093003164	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
933093003165	flagellar basal body rod protein FlgC; Provisional; Region: flgC; PRK12628
933093003166	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
933093003167	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
933093003168	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK06655
933093003169	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
933093003170	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
933093003171	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
933093003172	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
933093003173	flagellar basal body rod protein FlgF; Reviewed; Region: flgF; PRK12640
933093003174	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
933093003175	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
933093003176	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
933093003177	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
933093003178	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
933093003179	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK12701
933093003180	Flagellar L-ring protein; Region: FlgH; pfam02107
933093003181	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
933093003182	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
933093003183	Rod binding protein; Region: Rod-binding; cl01626
933093003184	flagellar rod assembly protein/muramidase FlgJ; Provisional; Region: flgJ; PRK12710
933093003185	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; pfam01832
933093003186	flagellar hook-associated protein FlgK; Provisional; Region: flgK; PRK12715
933093003187	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
933093003188	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
933093003189	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08870
933093003190	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
933093003191	ExoU and VipD-like proteins; homologus to patatin, cPLA2, and iPLA2; Region: Pat_ExoU_VipD_like; cd07207
933093003192	active site
933093003193	nucleophile elbow; other site
933093003194	ExoU and VipD-like proteins; homologus to patatin, cPLA2, and iPLA2; Region: Pat_ExoU_VipD_like; cd07207
933093003195	Ribosomal protein L24e/L24 is a ribosomal protein found in eukaryotes (L24) and in archaea (L24e, distinct from archaeal L24). L24e/L24 is located on the surface of the large subunit, adjacent to proteins L14 and L3, and near the translation factor...; Region: Ribosomal_L24e_L24; cl00909
933093003196	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
933093003197	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
933093003198	Dehydrogenases (flavoproteins) [Energy production and conversion]; Region: FixC; COG0644
933093003199	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
933093003200	Electron transfer flavoprotein-ubiquinone oxidoreductase; Region: ETF_QO; pfam05187
933093003201	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
933093003202	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
933093003203	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
933093003204	Walker A/P-loop; other site
933093003205	ATP binding site [chemical binding]; other site
933093003206	Q-loop/lid; other site
933093003207	ABC transporter signature motif; other site
933093003208	Walker B; other site
933093003209	D-loop; other site
933093003210	H-loop/switch region; other site
933093003211	Protein of unknown function (DUF2845); Region: DUF2845; pfam11006
933093003212	Chagasin family peptidase inhibitor I42; Region: Inhibitor_I42; pfam09394
933093003213	malate dehydrogenase; Provisional; Region: PRK13529
933093003214	Malic enzyme, N-terminal domain; Region: malic; pfam00390
933093003215	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
933093003216	NAD(P) binding site [chemical binding]; other site
933093003217	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
933093003218	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
933093003219	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
933093003220	Peptidase family M23; Region: Peptidase_M23; pfam01551
933093003221	RNA polymerase sigma factor RpoS; Region: rpoS_proteo; TIGR02394
933093003222	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
933093003223	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
933093003224	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
933093003225	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
933093003226	DNA binding residues [nucleotide binding]
933093003227	homogentisate 1,2-dioxygenase; Provisional; Region: PRK05341
933093003228	hypothetical protein; Validated; Region: PRK00110
933093003229	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
933093003230	active site
933093003231	putative DNA-binding cleft [nucleotide binding]; other site
933093003232	dimer interface [polypeptide binding]; other site
933093003233	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
933093003234	RuvA N terminal domain; Region: RuvA_N; pfam01330
933093003235	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
933093003236	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
933093003237	sensor protein QseC; Provisional; Region: PRK10337
933093003238	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
933093003239	dimer interface [polypeptide binding]; other site
933093003240	phosphorylation site [posttranslational modification]
933093003241	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
933093003242	ATP binding site [chemical binding]; other site
933093003243	Mg2+ binding site [ion binding]; other site
933093003244	G-X-G motif; other site
933093003245	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
933093003246	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
933093003247	active site
933093003248	phosphorylation site [posttranslational modification]
933093003249	intermolecular recognition site; other site
933093003250	dimerization interface [polypeptide binding]; other site
933093003251	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
933093003252	DNA binding site [nucleotide binding]
933093003253	intracellular septation protein A; Reviewed; Region: PRK00259
933093003254	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
933093003255	N-acetyl-D-glucosamine binding site [chemical binding]; other site
933093003256	catalytic residue [active]
933093003257	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
933093003258	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
933093003259	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
933093003260	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
933093003261	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
933093003262	hydroxyacylglutathione hydrolase; Region: GSH_gloB; TIGR03413
933093003263	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
933093003264	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
933093003265	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
933093003266	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
933093003267	homodimer interface [polypeptide binding]; other site
933093003268	NADP binding site [chemical binding]; other site
933093003269	substrate binding site [chemical binding]; other site
933093003270	FimV N-terminal domain; Region: FimV_core; TIGR03505
933093003271	Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits; Region: iSH2_PI3K_IA_R; cl17108
933093003272	heterodimer interface [polypeptide binding]; other site
933093003273	FimV C-terminal domain; Region: FimV_Cterm; TIGR03504
933093003274	Predicted integral membrane protein (DUF2269); Region: DUF2269; pfam10027
933093003275	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, subunit 9, 39 kDa, (NDUFA9) -like, atypical (a) SDRs; Region: NDUFA9_like_SDR_a; cd05271
933093003276	NADH(P)-binding; Region: NAD_binding_10; pfam13460
933093003277	putative NAD(P) binding site [chemical binding]; other site
933093003278	active site
933093003279	DoxX-like family; Region: DoxX_3; pfam13781
933093003280	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
933093003281	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
933093003282	dimerization interface 3.5A [polypeptide binding]; other site
933093003283	active site
933093003284	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
933093003285	active site
933093003286	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
933093003287	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
933093003288	pyridoxal 5'-phosphate binding site [chemical binding]; other site
933093003289	catalytic residue [active]
933093003290	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
933093003291	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
933093003292	substrate binding site [chemical binding]; other site
933093003293	active site
933093003294	catalytic residues [active]
933093003295	heterodimer interface [polypeptide binding]; other site
933093003296	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
933093003297	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
933093003298	active site
933093003299	HIGH motif; other site
933093003300	nucleotide binding site [chemical binding]; other site
933093003301	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
933093003302	KMSKS motif; other site
933093003303	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
933093003304	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
933093003305	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
933093003306	active site
933093003307	HIGH motif; other site
933093003308	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
933093003309	KMSKS motif; other site
933093003310	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
933093003311	tRNA binding surface [nucleotide binding]; other site
933093003312	anticodon binding site; other site
933093003313	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
933093003314	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
933093003315	Sulfatase; Region: Sulfatase; pfam00884
933093003316	GIY-YIG domain of uncharacterized hypothetical protein found in bacteria; Region: GIY-YIG_unchar_3; cd10448
933093003317	GIY-YIG motif/motif A; other site
933093003318	putative active site [active]
933093003319	putative metal binding site [ion binding]; other site
933093003320	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
933093003321	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
933093003322	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
933093003323	type II secretion system protein E; Region: type_II_gspE; TIGR02533
933093003324	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
933093003325	Walker A motif; other site
933093003326	ATP binding site [chemical binding]; other site
933093003327	Walker B motif; other site
933093003328	Sporulation related domain; Region: SPOR; pfam05036
933093003329	type II secretion system protein D; Region: type_II_gspD; TIGR02517
933093003330	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
933093003331	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
933093003332	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
933093003333	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
933093003334	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
933093003335	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
933093003336	Cache domain; Region: Cache_1; pfam02743
933093003337	Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]; Region: CyaA; COG2114
933093003338	cyclase homology domain; Region: CHD; cd07302
933093003339	nucleotidyl binding site; other site
933093003340	metal binding site [ion binding]; metal-binding site
933093003341	dimer interface [polypeptide binding]; other site
933093003342	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093003343	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
933093003344	putative substrate translocation pore; other site
933093003345	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093003346	Major Facilitator Superfamily; Region: MFS_1; pfam07690
933093003347	putative substrate translocation pore; other site
933093003348	IucA / IucC family; Region: IucA_IucC; pfam04183
933093003349	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
933093003350	Domain of unknown function (DUF4286); Region: DUF4286; pfam14114
933093003351	glycoside hydrolase family 64 (beta-1,3-glucanases which produce specific pentasaccharide oligomers) and thaumatin-like proteins; Region: GH64-TLP-SF; cl02511
933093003352	glycoside hydrolase family 64 (beta-1,3-glucanases which produce specific pentasaccharide oligomers) and thaumatin-like proteins; Region: GH64-TLP-SF; cl02511
933093003353	Sporulation related domain; Region: SPOR; pfam05036
933093003354	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
933093003355	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
933093003356	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
933093003357	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
933093003358	protein binding site [polypeptide binding]; other site
933093003359	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
933093003360	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; cl00650
933093003361	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
933093003362	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
933093003363	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
933093003364	RNA binding surface [nucleotide binding]; other site
933093003365	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
933093003366	active site
933093003367	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
933093003368	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
933093003369	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
933093003370	FeS/SAM binding site; other site
933093003371	TRAM domain; Region: TRAM; pfam01938
933093003372	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093003373	putative substrate translocation pore; other site
933093003374	Major Facilitator Superfamily; Region: MFS_1; pfam07690
933093003375	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
933093003376	Flagellar protein FliS; Region: FliS; cl00654
933093003377	flagellar capping protein; Provisional; Region: PRK12765
933093003378	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
933093003379	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
933093003380	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
933093003381	flagellin; Provisional; Region: PRK12806
933093003382	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
933093003383	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
933093003384	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
933093003385	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
933093003386	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
933093003387	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
933093003388	Uncharacterized protein conserved in bacteria [Function unknown]; Region: DedD; COG3147
933093003389	Sporulation related domain; Region: SPOR; pfam05036
933093003390	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
933093003391	Colicin V production protein; Region: Colicin_V; pfam02674
933093003392	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
933093003393	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
933093003394	active site
933093003395	(T/H)XGH motif; other site
933093003396	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
933093003397	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
933093003398	Lipopolysaccharide-assembly; Region: LptE; cl01125
933093003399	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
933093003400	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
933093003401	HIGH motif; other site
933093003402	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
933093003403	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
933093003404	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
933093003405	active site
933093003406	KMSKS motif; other site
933093003407	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
933093003408	tRNA binding surface [nucleotide binding]; other site
933093003409	apolipoprotein N-acyltransferase; Region: lnt; TIGR00546
933093003410	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
933093003411	putative active site [active]
933093003412	catalytic triad [active]
933093003413	putative dimer interface [polypeptide binding]; other site
933093003414	Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism]; Region: LYS9; COG1748
933093003415	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
933093003416	aldehyde dehydrogenase family 7 member; Region: PLN02315
933093003417	NAD+-dependent alpha-aminoadipic semialdehyde dehydrogenase, ALDH family members 7A1 and 7B; Region: ALDH_F7_AASADH; cd07130
933093003418	tetrameric interface [polypeptide binding]; other site
933093003419	NAD binding site [chemical binding]; other site
933093003420	catalytic residues [active]
933093003421	3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]; Region: FadB; COG1250
933093003422	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
933093003423	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
933093003424	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
933093003425	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
933093003426	substrate binding site [chemical binding]; other site
933093003427	oxyanion hole (OAH) forming residues; other site
933093003428	trimer interface [polypeptide binding]; other site
933093003429	acetyl-CoA acetyltransferase; Provisional; Region: PRK09052
933093003430	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
933093003431	dimer interface [polypeptide binding]; other site
933093003432	active site
933093003433	DNA-directed RNA polymerase subunit A''; Validated; Region: PRK04309
933093003434	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
933093003435	Sel1-like repeats; Region: SEL1; smart00671
933093003436	Sel1-like repeats; Region: SEL1; smart00671
933093003437	Sel1-like repeats; Region: SEL1; smart00671
933093003438	Sel1-like repeats; Region: SEL1; smart00671
933093003439	Sel1-like repeats; Region: SEL1; smart00671
933093003440	NADH dehydrogenase subunit 6; Provisional; Region: ND6; MTH00152
933093003441	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
933093003442	PAS domain; Region: PAS_9; pfam13426
933093003443	putative active site [active]
933093003444	heme pocket [chemical binding]; other site
933093003445	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
933093003446	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
933093003447	metal binding site [ion binding]; metal-binding site
933093003448	active site
933093003449	I-site; other site
933093003450	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
933093003451	Type II secretion system (T2SS), protein K; Region: T2SK; pfam03934
933093003452	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
933093003453	type II secretion system protein J; Region: gspJ; TIGR01711
933093003454	Type II secretion system (T2SS), protein J; Region: T2SJ; pfam11612
933093003455	Type II secretion system (T2SS), protein I; Region: T2SI; pfam02501
933093003456	Type II transport protein GspH; Region: GspH; pfam12019
933093003457	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
933093003458	type II secretion system protein G; Region: typeII_sec_gspG; TIGR01710
933093003459	Type II secretion system (T2SS), protein G; Region: T2SG; pfam08334
933093003460	type II secretion system protein F; Region: GspF; TIGR02120
933093003461	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
933093003462	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
933093003463	glutamine synthetase; Provisional; Region: glnA; PRK09469
933093003464	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
933093003465	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
933093003466	Domain of unknown function (DUF4124); Region: DUF4124; pfam13511
933093003467	hypothetical protein; Validated; Region: PRK02101
933093003468	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
933093003469	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
933093003470	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
933093003471	catalytic residue [active]
933093003472	heat shock protein 90; Provisional; Region: PRK05218
933093003473	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
933093003474	ATP binding site [chemical binding]; other site
933093003475	Mg2+ binding site [ion binding]; other site
933093003476	G-X-G motif; other site
933093003477	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
933093003478	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
933093003479	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
933093003480	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
933093003481	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
933093003482	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
933093003483	RNA/DNA hybrid binding site [nucleotide binding]; other site
933093003484	active site
933093003485	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
933093003486	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
933093003487	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
933093003488	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
933093003489	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
933093003490	iojap-like ribosome-associated protein; Region: iojap_ybeB; TIGR00090
933093003491	POT family; Region: PTR2; cl17359
933093003492	amino acid/peptide transporter (Peptide:H+ symporter), bacterial; Region: yjdL_sub1_fam; TIGR00924
933093003493	urocanate hydratase; Provisional; Region: PRK05414
933093003494	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
933093003495	active sites [active]
933093003496	tetramer interface [polypeptide binding]; other site
933093003497	Coniferyl aldehyde dehydrogenase-like; Region: ALDH_CALDH_CalB; cd07133
933093003498	NAD(P) binding site [chemical binding]; other site
933093003499	catalytic residues [active]
933093003500	short chain dehydrogenase; Provisional; Region: PRK08278
933093003501	human hydroxysteroid dehydrogenase-like protein 2 (HSDL2), classical (c) SDRs; Region: HSDL2_SDR_c; cd09762
933093003502	NAD(P) binding site [chemical binding]; other site
933093003503	homodimer interface [polypeptide binding]; other site
933093003504	active site
933093003505	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
933093003506	RNA/DNA hybrid binding site [nucleotide binding]; other site
933093003507	active site
933093003508	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
933093003509	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
933093003510	active site
933093003511	catalytic site [active]
933093003512	substrate binding site [chemical binding]; other site
933093003513	Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376
933093003514	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
933093003515	phosphodiesterase; Provisional; Region: PRK12704
933093003516	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
933093003517	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
933093003518	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
933093003519	Ligand Binding Site [chemical binding]; other site
933093003520	Uncharacterized ACR, COG1399; Region: DUF177; cl00616
933093003521	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
933093003522	putative phosphate acyltransferase; Provisional; Region: PRK05331
933093003523	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
933093003524	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
933093003525	dimer interface [polypeptide binding]; other site
933093003526	active site
933093003527	CoA binding pocket [chemical binding]; other site
933093003528	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
933093003529	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
933093003530	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
933093003531	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
933093003532	NAD(P) binding site [chemical binding]; other site
933093003533	homotetramer interface [polypeptide binding]; other site
933093003534	homodimer interface [polypeptide binding]; other site
933093003535	active site
933093003536	acyl carrier protein; Provisional; Region: acpP; PRK00982
933093003537	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
933093003538	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
933093003539	dimer interface [polypeptide binding]; other site
933093003540	active site
933093003541	YceG-like family; Region: YceG; pfam02618
933093003542	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
933093003543	dimerization interface [polypeptide binding]; other site
933093003544	thymidylate kinase; Validated; Region: tmk; PRK00698
933093003545	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
933093003546	TMP-binding site; other site
933093003547	ATP-binding site [chemical binding]; other site
933093003548	DNA polymerase III, delta subunit; Region: DNA_pol3_delta2; pfam13177
933093003549	DNA polymerase III subunit delta'; Validated; Region: PRK08485
933093003550	PilZ domain; Region: PilZ; cl01260
933093003551	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
933093003552	active site
933093003553	anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585
933093003554	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093003555	Major Facilitator Superfamily; Region: MFS_1; pfam07690
933093003556	putative substrate translocation pore; other site
933093003557	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
933093003558	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093003559	dolichyl-phosphate beta-D-mannosyltransferase; Region: PLN02726
933093003560	DPM1_like represents putative enzymes similar to eukaryotic DPM1; Region: DPM1_like; cd06442
933093003561	Ligand binding site; other site
933093003562	Putative Catalytic site; other site
933093003563	DXD motif; other site
933093003564	GtrA-like protein; Region: GtrA; pfam04138
933093003565	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
933093003566	Choline Kinase (ChoK). The ChoK subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and...; Region: ChoK; cd05151
933093003567	Phosphotransferase enzyme family; Region: APH; pfam01636
933093003568	active site
933093003569	ATP binding site [chemical binding]; other site
933093003570	substrate binding site [chemical binding]; other site
933093003571	dimer interface [polypeptide binding]; other site
933093003572	Uncharacterized bacterial subgroup of the DEDDy 3'-5' exonuclease domain of family-B DNA polymerases; Region: DNA_polB_like1_exo; cd05782
933093003573	active site
933093003574	catalytic site [active]
933093003575	substrate binding site [chemical binding]; other site
933093003576	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB; Region: DNA_pol_B_exo2; pfam10108
933093003577	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
933093003578	N-acetyl-D-glucosamine binding site [chemical binding]; other site
933093003579	catalytic residue [active]
933093003580	adenylate kinase; Reviewed; Region: adk; PRK00279
933093003581	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
933093003582	AMP-binding site [chemical binding]; other site
933093003583	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
933093003584	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
933093003585	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
933093003586	catalytic residues [active]
933093003587	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
933093003588	Glycerol kinase [Energy production and conversion]; Region: GlpK; COG0554
933093003589	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
933093003590	N- and C-terminal domain interface [polypeptide binding]; other site
933093003591	active site
933093003592	MgATP binding site [chemical binding]; other site
933093003593	catalytic site [active]
933093003594	metal binding site [ion binding]; metal-binding site
933093003595	glycerol binding site [chemical binding]; other site
933093003596	homotetramer interface [polypeptide binding]; other site
933093003597	homodimer interface [polypeptide binding]; other site
933093003598	FBP binding site [chemical binding]; other site
933093003599	protein IIAGlc interface [polypeptide binding]; other site
933093003600	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
933093003601	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
933093003602	dimer interface [polypeptide binding]; other site
933093003603	active site
933093003604	citrylCoA binding site [chemical binding]; other site
933093003605	NADH binding [chemical binding]; other site
933093003606	cationic pore residues; other site
933093003607	oxalacetate/citrate binding site [chemical binding]; other site
933093003608	coenzyme A binding site [chemical binding]; other site
933093003609	catalytic triad [active]
933093003610	Phosphorylase superfamily; Region: PNP_UDP_1; pfam01048
933093003611	DNA gyrase subunit A; Validated; Region: PRK05560
933093003612	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
933093003613	CAP-like domain; other site
933093003614	active site
933093003615	primary dimer interface [polypeptide binding]; other site
933093003616	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
933093003617	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
933093003618	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
933093003619	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
933093003620	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
933093003621	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
933093003622	3-phosphoserine/phosphohydroxythreonine aminotransferase; Provisional; Region: PRK05355
933093003623	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
933093003624	catalytic residue [active]
933093003625	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
933093003626	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
933093003627	hinge; other site
933093003628	active site
933093003629	cytidylate kinase; Provisional; Region: cmk; PRK00023
933093003630	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
933093003631	CMP-binding site; other site
933093003632	The sites determining sugar specificity; other site
933093003633	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
933093003634	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
933093003635	RNA binding site [nucleotide binding]; other site
933093003636	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
933093003637	RNA binding site [nucleotide binding]; other site
933093003638	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
933093003639	RNA binding site [nucleotide binding]; other site
933093003640	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
933093003641	RNA binding site [nucleotide binding]; other site
933093003642	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
933093003643	RNA binding site [nucleotide binding]; other site
933093003644	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
933093003645	RNA binding site [nucleotide binding]; other site
933093003646	Protein of unknown function (DUF1049); Region: DUF1049; pfam06305
933093003647	tetratricopeptide repeat protein; Provisional; Region: PRK11788
933093003648	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
933093003649	TPR motif; other site
933093003650	binding surface
933093003651	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
933093003652	binding surface
933093003653	TPR motif; other site
933093003654	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
933093003655	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
933093003656	inhibitor-cofactor binding pocket; inhibition site
933093003657	pyridoxal 5'-phosphate binding site [chemical binding]; other site
933093003658	catalytic residue [active]
933093003659	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
933093003660	active site
933093003661	dimer interface [polypeptide binding]; other site
933093003662	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
933093003663	ExoU and VipD-like proteins; homologus to patatin, cPLA2, and iPLA2; Region: Pat_ExoU_VipD_like; cd07207
933093003664	active site
933093003665	nucleophile elbow; other site
933093003666	Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396
933093003667	classical (c) SDRs; Region: SDR_c; cd05233
933093003668	3-oxoacyl-(acyl-carrier-protein) reductase, putative; Region: fabG_rel; TIGR01831
933093003669	NAD(P) binding site [chemical binding]; other site
933093003670	active site
933093003671	Tfp pilus assembly protein FimT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimT; COG4970
933093003672	Chorismate lyase; Region: Chor_lyase; cl01230
933093003673	4-hydroxybenzoate polyprenyltransferase; Reviewed; Region: ubiA; PRK12847
933093003674	UbiA prenyltransferase family; Region: UbiA; pfam01040
933093003675	Glycine zipper 2TM domain; Region: Rick_17kDa_Anti; cl10470
933093003676	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
933093003677	FAD binding domain; Region: FAD_binding_4; pfam01565
933093003678	Berberine and berberine like; Region: BBE; pfam08031
933093003679	Class I aldolases; Region: Aldolase_Class_I; cl17187
933093003680	catalytic residue [active]
933093003681	purine nucleoside phosphorylase; Provisional; Region: PRK08202
933093003682	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
933093003683	active site
933093003684	catalytic motif [active]
933093003685	Zn binding site [ion binding]; other site
933093003686	two-component sensor protein; Provisional; Region: cpxA; PRK09470
933093003687	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
933093003688	dimerization interface [polypeptide binding]; other site
933093003689	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
933093003690	dimer interface [polypeptide binding]; other site
933093003691	phosphorylation site [posttranslational modification]
933093003692	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
933093003693	ATP binding site [chemical binding]; other site
933093003694	Mg2+ binding site [ion binding]; other site
933093003695	G-X-G motif; other site
933093003696	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
933093003697	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
933093003698	active site
933093003699	phosphorylation site [posttranslational modification]
933093003700	intermolecular recognition site; other site
933093003701	dimerization interface [polypeptide binding]; other site
933093003702	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
933093003703	DNA binding site [nucleotide binding]
933093003704	FOG: CBS domain [General function prediction only]; Region: COG0517
933093003705	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
933093003706	Transporter associated domain; Region: CorC_HlyC; smart01091
933093003707	metal-binding heat shock protein; Provisional; Region: PRK00016
933093003708	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
933093003709	PhoH-like protein; Region: PhoH; pfam02562
933093003710	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
933093003711	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
933093003712	active site
933093003713	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
933093003714	Telomere recombination; Region: Sua5_yciO_yrdC; cl00305
933093003715	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
933093003716	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
933093003717	active site
933093003718	HIGH motif; other site
933093003719	dimer interface [polypeptide binding]; other site
933093003720	KMSKS motif; other site
933093003721	Rec8/ScpA/Scc1-like protein (kleisin family) [Replication,    recombination, and repair]; Region: scpA; COG1354
933093003722	Putative transcriptional regulators (Ypuh-like); Region: DUF387; pfam04079
933093003723	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
933093003724	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
933093003725	RNA binding surface [nucleotide binding]; other site
933093003726	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
933093003727	probable active site [active]
933093003728	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
933093003729	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
933093003730	DNA binding residues [nucleotide binding]
933093003731	dimerization interface [polypeptide binding]; other site
933093003732	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
933093003733	Dihydrouridine synthase (Dus); Region: Dus; pfam01207
933093003734	non-haem dioxygenase in morphine synthesis N-terminal; Region: DIOX_N; pfam14226
933093003735	Isopenicillin N synthase and related dioxygenases [General function prediction only]; Region: PcbC; COG3491
933093003736	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy; pfam03171
933093003737	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
933093003738	substrate binding site [chemical binding]; other site
933093003739	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
933093003740	putative transporter; Provisional; Region: PRK10504
933093003741	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093003742	putative substrate translocation pore; other site
933093003743	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093003744	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
933093003745	TRAM domain; Region: TRAM; pfam01938
933093003746	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
933093003747	S-adenosylmethionine binding site [chemical binding]; other site
933093003748	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
933093003749	HD domain; Region: HD_4; pfam13328
933093003750	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
933093003751	synthetase active site [active]
933093003752	NTP binding site [chemical binding]; other site
933093003753	metal binding site [ion binding]; metal-binding site
933093003754	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
933093003755	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
933093003756	Xcc1710_like family, specific to proteobacteria. Xcc1710 is a hypothetical protein from Xanthomonas campestris pv. campestris str. ATCC 33913, similar to Mth938, a hypothetical protein encoded by the Methanobacterium thermoautotrophicum (Mth) genome; Region: Xcc1710_like; cd05560
933093003757	aminotransferase; Validated; Region: PRK08175
933093003758	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
933093003759	pyridoxal 5'-phosphate binding site [chemical binding]; other site
933093003760	homodimer interface [polypeptide binding]; other site
933093003761	catalytic residue [active]
933093003762	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4255
933093003763	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
933093003764	DHH family; Region: DHH; pfam01368
933093003765	DHHA1 domain; Region: DHHA1; pfam02272
933093003766	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
933093003767	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
933093003768	FMN binding site [chemical binding]; other site
933093003769	active site
933093003770	catalytic residues [active]
933093003771	substrate binding site [chemical binding]; other site
933093003772	preprotein translocase subunit SecA; Reviewed; Region: secA; PRK13104
933093003773	DEAD/DEAH box helicase; Region: DEAD; pfam00270
933093003774	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
933093003775	SEC-C motif; Region: SEC-C; pfam02810
933093003776	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
933093003777	Putative MetA-pathway of phenol degradation; Region: Phenol_MetA_deg; pfam13557
933093003778	hypothetical protein; Provisional; Region: PRK05287
933093003779	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
933093003780	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
933093003781	CoA-binding site [chemical binding]; other site
933093003782	ATP-binding [chemical binding]; other site
933093003783	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
933093003784	D-Ala-D-Ala carboxypeptidase 3 (S13) family; Region: Peptidase_S13; cl17429
933093003785	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
933093003786	adenosylmethionine-8-amino-7-oxononanoate transaminase; Region: bioA; TIGR00508
933093003787	inhibitor-cofactor binding pocket; inhibition site
933093003788	pyridoxal 5'-phosphate binding site [chemical binding]; other site
933093003789	catalytic residue [active]
933093003790	biotin synthase; Region: bioB; TIGR00433
933093003791	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
933093003792	FeS/SAM binding site; other site
933093003793	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
933093003794	8-amino-7-oxononanoate synthase; Reviewed; Region: PRK05958
933093003795	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
933093003796	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
933093003797	catalytic residue [active]
933093003798	pimelyl-[acyl-carrier protein] methyl ester esterase; Region: bioH; TIGR01738
933093003799	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
933093003800	AAA domain; Region: AAA_26; pfam13500
933093003801	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
933093003802	putative regulatory protein, FmdB family; Region: CxxC_CxxC_SSSS; TIGR02605
933093003803	Uncharacterized conserved protein [Function unknown]; Region: COG2928
933093003804	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
933093003805	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
933093003806	dimer interface [polypeptide binding]; other site
933093003807	anticodon binding site; other site
933093003808	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
933093003809	homodimer interface [polypeptide binding]; other site
933093003810	motif 1; other site
933093003811	active site
933093003812	motif 2; other site
933093003813	GAD domain; Region: GAD; pfam02938
933093003814	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
933093003815	motif 3; other site
933093003816	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
933093003817	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
933093003818	Mechanosensitive ion channel; Region: MS_channel; pfam00924
933093003819	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
933093003820	putative DNA-binding cleft [nucleotide binding]; other site
933093003821	putative DNA clevage site; other site
933093003822	molecular lever; other site
933093003823	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
933093003824	Catalytic domain of Protein Kinases; Region: PKc; cd00180
933093003825	active site
933093003826	ATP binding site [chemical binding]; other site
933093003827	substrate binding site [chemical binding]; other site
933093003828	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
933093003829	substrate binding site [chemical binding]; other site
933093003830	activation loop (A-loop); other site
933093003831	activation loop (A-loop); other site
933093003832	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
933093003833	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
933093003834	putative DNA binding site [nucleotide binding]; other site
933093003835	putative Zn2+ binding site [ion binding]; other site
933093003836	AsnC family; Region: AsnC_trans_reg; pfam01037
933093003837	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
933093003838	Coenzyme A binding pocket [chemical binding]; other site
933093003839	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
933093003840	GAF domain; Region: GAF; pfam01590
933093003841	Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]; Region: CyaA; COG2114
933093003842	cyclase homology domain; Region: CHD; cd07302
933093003843	nucleotidyl binding site; other site
933093003844	metal binding site [ion binding]; metal-binding site
933093003845	dimer interface [polypeptide binding]; other site
933093003846	Phosphotransferase enzyme family; Region: APH; pfam01636
933093003847	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
933093003848	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
933093003849	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
933093003850	putative active site pocket [active]
933093003851	dimerization interface [polypeptide binding]; other site
933093003852	putative catalytic residue [active]
933093003853	Dot/Icm substrate protein; Region: SidE; pfam12252
933093003854	aminopeptidase N; Provisional; Region: pepN; PRK14015
933093003855	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
933093003856	Zn binding site [ion binding]; other site
933093003857	C factor cell-cell signaling protein; Provisional; Region: PRK09009
933093003858	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
933093003859	NAD(P) binding site [chemical binding]; other site
933093003860	active site
933093003861	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
933093003862	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
933093003863	Coenzyme A binding pocket [chemical binding]; other site
933093003864	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
933093003865	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
933093003866	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
933093003867	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
933093003868	dihydrolipoamide acetyltransferase; Reviewed; Region: PRK11855
933093003869	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
933093003870	E3 interaction surface; other site
933093003871	lipoyl attachment site [posttranslational modification]; other site
933093003872	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
933093003873	E3 interaction surface; other site
933093003874	lipoyl attachment site [posttranslational modification]; other site
933093003875	e3 binding domain; Region: E3_binding; pfam02817
933093003876	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
933093003877	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
933093003878	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
933093003879	dimer interface [polypeptide binding]; other site
933093003880	TPP-binding site [chemical binding]; other site
933093003881	Membrane protein required for beta-lactamase induction [Defense mechanisms]; Region: AmpE; cl17896
933093003882	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
933093003883	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
933093003884	Lipoproteins [Cell envelope biogenesis, outer membrane]; Region: RlpA; COG0797
933093003885	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
933093003886	Sporulation related domain; Region: SPOR; pfam05036
933093003887	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
933093003888	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
933093003889	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
933093003890	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
933093003891	D-Alanine aminotransferase (D-AAT_like): D-amino acid aminotransferase catalyzes transamination between D-amino acids and their respective alpha-keto acids. It plays a major role in the synthesis of bacterial cell wall components like D-alanine and...; Region: D-AAT_like; cd01558
933093003892	homodimer interface [polypeptide binding]; other site
933093003893	substrate-cofactor binding pocket; other site
933093003894	pyridoxal 5'-phosphate binding site [chemical binding]; other site
933093003895	catalytic residue [active]
933093003896	lipoate-protein ligase B; Provisional; Region: PRK14342
933093003897	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
933093003898	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
933093003899	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
933093003900	active site
933093003901	LssY C-terminus; Region: LssY_C; pfam14067
933093003902	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
933093003903	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39_likeD; cd02421
933093003904	type I secretion system ATPase, LssB family; Region: type_I_sec_LssB; TIGR03375
933093003905	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
933093003906	ATP-binding cassette domain of bacteriocin exporters, subfamily C; Region: ABCC_bacteriocin_exporters; cd03245
933093003907	Walker A/P-loop; other site
933093003908	ATP binding site [chemical binding]; other site
933093003909	Q-loop/lid; other site
933093003910	ABC transporter signature motif; other site
933093003911	Walker B; other site
933093003912	D-loop; other site
933093003913	H-loop/switch region; other site
933093003914	ATP-binding cassette domain of bacteriocin exporters, subfamily C; Region: ABCC_bacteriocin_exporters; cd03245
933093003915	ABC transporter; Region: ABC_tran; pfam00005
933093003916	Q-loop/lid; other site
933093003917	ABC transporter signature motif; other site
933093003918	Walker B; other site
933093003919	D-loop; other site
933093003920	H-loop/switch region; other site
933093003921	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
933093003922	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
933093003923	HlyD family secretion protein; Region: HlyD_3; pfam13437
933093003924	PAS domain; Region: PAS_9; pfam13426
933093003925	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
933093003926	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
933093003927	metal binding site [ion binding]; metal-binding site
933093003928	active site
933093003929	I-site; other site
933093003930	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
933093003931	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
933093003932	active site
933093003933	Domain of unknown function (DUF1820); Region: DUF1820; pfam08850
933093003934	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
933093003935	type IV-A pilus assembly ATPase PilB; Region: type_IV_pilB; TIGR02538
933093003936	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
933093003937	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
933093003938	Walker A motif; other site
933093003939	ATP binding site [chemical binding]; other site
933093003940	Walker B motif; other site
933093003941	Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459
933093003942	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
933093003943	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
933093003944	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
933093003945	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
933093003946	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
933093003947	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
933093003948	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
933093003949	ligand binding site [chemical binding]; other site
933093003950	CAAX protease self-immunity; Region: Abi; pfam02517
933093003951	PEP synthetase regulatory protein; Provisional; Region: PRK05339
933093003952	2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425
933093003953	2-methylcitrate dehydratase; Region: prpD; TIGR02330
933093003954	Escherichia coli (Ec) 2-methylcitrate synthase (2MCS)_like. 2MCS catalyzes the condensation of propionyl-coenzyme A (PrCoA) and oxalacetate (OAA) to form 2-methylcitrate and coenzyme A (CoA) during propionate metabolism. Citrate synthase (CS) catalyzes...; Region: Ec2MCS_like; cd06108
933093003955	dimer interface [polypeptide binding]; other site
933093003956	Citrate synthase; Region: Citrate_synt; pfam00285
933093003957	active site
933093003958	citrylCoA binding site [chemical binding]; other site
933093003959	oxalacetate/citrate binding site [chemical binding]; other site
933093003960	coenzyme A binding site [chemical binding]; other site
933093003961	catalytic triad [active]
933093003962	Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384
933093003963	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
933093003964	Uncharacterized conserved protein [Function unknown]; Region: COG4121
933093003965	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
933093003966	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093003967	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
933093003968	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093003969	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
933093003970	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
933093003971	inhibitor-cofactor binding pocket; inhibition site
933093003972	pyridoxal 5'-phosphate binding site [chemical binding]; other site
933093003973	catalytic residue [active]
933093003974	Rubredoxin [Energy production and conversion]; Region: COG1773
933093003975	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
933093003976	iron binding site [ion binding]; other site
933093003977	Uncharacterized protein family (UPF0093); Region: UPF0093; pfam03653
933093003978	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
933093003979	poly(A) polymerase; Region: pcnB; TIGR01942
933093003980	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
933093003981	active site
933093003982	NTP binding site [chemical binding]; other site
933093003983	metal binding triad [ion binding]; metal-binding site
933093003984	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
933093003985	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
933093003986	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
933093003987	catalytic center binding site [active]
933093003988	ATP binding site [chemical binding]; other site
933093003989	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
933093003990	Ligand Binding Site [chemical binding]; other site
933093003991	GTP-binding protein Der; Reviewed; Region: PRK00093
933093003992	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
933093003993	G1 box; other site
933093003994	GTP/Mg2+ binding site [chemical binding]; other site
933093003995	Switch I region; other site
933093003996	G2 box; other site
933093003997	Switch II region; other site
933093003998	G3 box; other site
933093003999	G4 box; other site
933093004000	G5 box; other site
933093004001	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
933093004002	G1 box; other site
933093004003	GTP/Mg2+ binding site [chemical binding]; other site
933093004004	Switch I region; other site
933093004005	G2 box; other site
933093004006	G3 box; other site
933093004007	Switch II region; other site
933093004008	G4 box; other site
933093004009	G5 box; other site
933093004010	outer membrane assembly lipoprotein YfgL; Region: assembly_YfgL; TIGR03300
933093004011	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
933093004012	Trp docking motif [polypeptide binding]; other site
933093004013	active site
933093004014	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
933093004015	Uncharacterized protein conserved in bacteria (DUF2133); Region: DUF2133; pfam09976
933093004016	histidyl-tRNA synthetase; Region: hisS; TIGR00442
933093004017	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
933093004018	dimer interface [polypeptide binding]; other site
933093004019	motif 1; other site
933093004020	active site
933093004021	motif 2; other site
933093004022	motif 3; other site
933093004023	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
933093004024	anticodon binding site; other site
933093004025	Helix-turn-helix domain; Region: HTH_25; pfam13413
933093004026	type IV pilus biogenesis/stability protein PilW; Region: type_IV_pilW; TIGR02521
933093004027	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
933093004028	binding surface
933093004029	TPR motif; other site
933093004030	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
933093004031	binding surface
933093004032	TPR motif; other site
933093004033	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
933093004034	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
933093004035	FeS/SAM binding site; other site
933093004036	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
933093004037	active site
933093004038	multimer interface [polypeptide binding]; other site
933093004039	MiaE tRNA-modifying nonheme diiron monooxygenase, ferritin-like diiron-binding domain; Region: MiaE; cd07910
933093004040	active site
933093004041	dinuclear metal binding site [ion binding]; other site
933093004042	dimerization interface [polypeptide binding]; other site
933093004043	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
933093004044	putative active site [active]
933093004045	putative metal binding site [ion binding]; other site
933093004046	septum formation inhibitor; Reviewed; Region: minC; PRK00339
933093004047	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
933093004048	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
933093004049	Long-chain-fatty-acid--CoA ligase; Validated; Region: PRK07059
933093004050	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
933093004051	acyl-activating enzyme (AAE) consensus motif; other site
933093004052	putative AMP binding site [chemical binding]; other site
933093004053	putative active site [active]
933093004054	putative CoA binding site [chemical binding]; other site
933093004055	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
933093004056	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
933093004057	substrate binding pocket [chemical binding]; other site
933093004058	membrane-bound complex binding site; other site
933093004059	hinge residues; other site
933093004060	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
933093004061	putative active site [active]
933093004062	putative CoA binding site [chemical binding]; other site
933093004063	nudix motif; other site
933093004064	metal binding site [ion binding]; metal-binding site
933093004065	Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism]; Region: TrpE; COG0147
933093004066	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
933093004067	chorismate binding enzyme; Region: Chorismate_bind; cl10555
933093004068	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_x; TIGR03181
933093004069	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
933093004070	TPP-binding site [chemical binding]; other site
933093004071	tetramer interface [polypeptide binding]; other site
933093004072	heterodimer interface [polypeptide binding]; other site
933093004073	phosphorylation loop region [posttranslational modification]
933093004074	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
933093004075	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
933093004076	alpha subunit interface [polypeptide binding]; other site
933093004077	TPP binding site [chemical binding]; other site
933093004078	heterodimer interface [polypeptide binding]; other site
933093004079	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
933093004080	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
933093004081	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
933093004082	E3 interaction surface; other site
933093004083	lipoyl attachment site [posttranslational modification]; other site
933093004084	e3 binding domain; Region: E3_binding; pfam02817
933093004085	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
933093004086	Mechanosensitive ion channel; Region: MS_channel; pfam00924
933093004087	Uncharacterized conserved protein [Function unknown]; Region: COG0398
933093004088	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
933093004089	mercuric reductase; Validated; Region: PRK06370
933093004090	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
933093004091	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
933093004092	Nodulin-21 and CCC1-related protein family; Region: Nodulin-21_like_3; cd02434
933093004093	NMT1/THI5 like; Region: NMT1; pfam09084
933093004094	TRAP transporter solute receptor, TAXI family; Region: TRAP_TAXI; TIGR02122
933093004095	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
933093004096	glycine oxidase ThiO; Region: thiamin_ThiO; TIGR02352
933093004097	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
933093004098	ThiS interaction site; other site
933093004099	putative active site [active]
933093004100	tetramer interface [polypeptide binding]; other site
933093004101	HMP-P kinase/thiamin-monophosphate pyrophosphorylase; Region: PLN02898
933093004102	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
933093004103	dimer interface [polypeptide binding]; other site
933093004104	substrate binding site [chemical binding]; other site
933093004105	ATP binding site [chemical binding]; other site
933093004106	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
933093004107	thiamine phosphate binding site [chemical binding]; other site
933093004108	active site
933093004109	pyrophosphate binding site [ion binding]; other site
933093004110	molybdopterin biosynthesis-like protein MoeZ; Validated; Region: PRK07878
933093004111	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
933093004112	ATP binding site [chemical binding]; other site
933093004113	substrate interface [chemical binding]; other site
933093004114	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
933093004115	active site residue [active]
933093004116	S1/P1 nucleases and related enzymes; Region: S1-P1_nuclease; cd11010
933093004117	active site
933093004118	Zn binding site [ion binding]; other site
933093004119	tol-pal system beta propeller repeat protein TolB; Region: propeller_TolB; TIGR02800
933093004120	TolB amino-terminal domain; Region: TolB_N; pfam04052
933093004121	Uncharacterized protein conserved in bacteria (DUF2195); Region: DUF2195; cl02042
933093004122	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
933093004123	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
933093004124	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
933093004125	TolA protein; Region: tolA_full; TIGR02794
933093004126	TolA protein; Region: tolA_full; TIGR02794
933093004127	TonB C terminal; Region: TonB_2; pfam13103
933093004128	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
933093004129	TolR protein; Region: tolR; TIGR02801
933093004130	TolQ protein; Region: tolQ; TIGR02796
933093004131	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
933093004132	active site
933093004133	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
933093004134	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
933093004135	Walker A motif; other site
933093004136	ATP binding site [chemical binding]; other site
933093004137	Walker B motif; other site
933093004138	arginine finger; other site
933093004139	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
933093004140	RNA polymerase sigma factor RpoE; Provisional; Region: PRK09652
933093004141	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
933093004142	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
933093004143	DNA binding residues [nucleotide binding]
933093004144	Predicted aminomethyltransferase related to GcvT [General function prediction only]; Region: COG0354
933093004145	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
933093004146	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
933093004147	Bacterial NAD-glutamate dehydrogenase; Region: Bac_GDH; pfam05088
933093004148	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Region: ELFV_dehydrog; smart00839
933093004149	Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376
933093004150	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
933093004151	putative succinate semialdehyde dehydrogenase; Provisional; Region: PRK13968
933093004152	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
933093004153	NAD(P) binding site [chemical binding]; other site
933093004154	catalytic residues [active]
933093004155	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
933093004156	Peroxiredoxin (PRX)-like 1 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a conserved cysteine that aligns to the first cysteine in the CXXC motif of TRX. This does not correspond to the peroxidatic...; Region: PRX_like1; cd02969
933093004157	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
933093004158	putative catalytic residue [active]
933093004159	chromosome segregation protein; Provisional; Region: PRK03918
933093004160	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
933093004161	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
933093004162	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
933093004163	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
933093004164	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
933093004165	Global regulator protein family; Region: CsrA; pfam02599
933093004166	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474
933093004167	Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376
933093004168	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
933093004169	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
933093004170	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
933093004171	substrate binding site [chemical binding]; other site
933093004172	oxyanion hole (OAH) forming residues; other site
933093004173	trimer interface [polypeptide binding]; other site
933093004174	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
933093004175	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
933093004176	acetyl-CoA acetyltransferase; Provisional; Region: PRK08170
933093004177	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
933093004178	dimer interface [polypeptide binding]; other site
933093004179	active site
933093004180	potential protein location (hypothetical protein lp12_1537 [Legionella pneumophila subsp. pneumophila ATCC 43290]) that overlaps RNA (tRNA-S)
933093004181	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
933093004182	Leucine-rich repeats; other site
933093004183	Substrate binding site [chemical binding]; other site
933093004184	RES domain; Region: RES; smart00953
933093004185	Protein of unknown function (DUF2384); Region: DUF2384; pfam09722
933093004186	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
933093004187	S-adenosylmethionine binding site [chemical binding]; other site
933093004188	Phosphoenolpyruvate carboxylase; Region: PEPcase; cl17418
933093004189	Phosphoenolpyruvate carboxylase; Region: PEPcase; cl17418
933093004190	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_21; cd04680
933093004191	nudix motif; other site
933093004192	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
933093004193	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
933093004194	putative catalytic cysteine [active]
933093004195	gamma-glutamyl kinase; Provisional; Region: PRK05429
933093004196	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
933093004197	nucleotide binding site [chemical binding]; other site
933093004198	homotetrameric interface [polypeptide binding]; other site
933093004199	putative phosphate binding site [ion binding]; other site
933093004200	putative allosteric binding site; other site
933093004201	PUA domain; Region: PUA; pfam01472
933093004202	Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA; Region: HTH_TipAL-Mta; cd01106
933093004203	DNA binding residues [nucleotide binding]
933093004204	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
933093004205	dimer interface [polypeptide binding]; other site
933093004206	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
933093004207	Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA; Region: HTH_TipAL-Mta; cd01106
933093004208	DNA binding residues [nucleotide binding]
933093004209	dimer interface [polypeptide binding]; other site
933093004210	TipAS antibiotic-recognition domain; Region: TipAS; pfam07739
933093004211	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
933093004212	Coenzyme A binding pocket [chemical binding]; other site
933093004213	Uncharacterized protein family (UPF0157); Region: UPF0157; pfam04229
933093004214	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
933093004215	Coenzyme A binding pocket [chemical binding]; other site
933093004216	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
933093004217	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
933093004218	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
933093004219	Walker A/P-loop; other site
933093004220	ATP binding site [chemical binding]; other site
933093004221	Q-loop/lid; other site
933093004222	ABC transporter signature motif; other site
933093004223	Walker B; other site
933093004224	D-loop; other site
933093004225	H-loop/switch region; other site
933093004226	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
933093004227	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
933093004228	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
933093004229	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
933093004230	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
933093004231	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
933093004232	Beta-lactamase class D [Defense mechanisms]; Region: COG2602
933093004233	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
933093004234	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
933093004235	Penicillinase repressor; Region: Pencillinase_R; pfam03965
933093004236	tRNA pseudouridine synthase D (TruD); Region: TruD; pfam01142
933093004237	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
933093004238	Permutation of conserved domain; other site
933093004239	active site
933093004240	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
933093004241	putative hydrolase; Provisional; Region: PRK10985
933093004242	copper-(or silver)-translocating P-type ATPase; Region: ATPase-IB1_Cu; TIGR01511
933093004243	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
933093004244	Soluble P-type ATPase [General function prediction only]; Region: COG4087
933093004245	putative adenylate-forming enzyme; Region: aden_form_hyp; TIGR02304
933093004246	Coenzyme F390 synthetase [Coenzyme metabolism]; Region: PaaK; COG1541
933093004247	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
933093004248	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
933093004249	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
933093004250	NAD(P) binding site [chemical binding]; other site
933093004251	active site
933093004252	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK07204
933093004253	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
933093004254	dimer interface [polypeptide binding]; other site
933093004255	active site
933093004256	CoA binding pocket [chemical binding]; other site
933093004257	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
933093004258	This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1; Region: GT1_UGDG_like; cd03817
933093004259	putative ADP-binding pocket [chemical binding]; other site
933093004260	PAP2 superfamily C-terminal; Region: PAP2_C; pfam14360
933093004261	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
933093004262	FAD binding domain; Region: FAD_binding_4; pfam01565
933093004263	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
933093004264	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
933093004265	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
933093004266	putative urate catabolism protein; Region: uraD_N-term-dom; TIGR03212
933093004267	Catalytic domain of bacterial PuuE allantoinases, Schizosaccharomyces pombe chitin deacetylase 1 (SpCDA1), and similar proteins; Region: CE4_PuuE_SpCDA1; cd10977
933093004268	active site
933093004269	catalytic site [active]
933093004270	tetramer interface [polypeptide binding]; other site
933093004271	enterobactin exporter EntS; Provisional; Region: PRK10489
933093004272	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093004273	putative substrate translocation pore; other site
933093004274	Predicted membrane protein [Function unknown]; Region: COG2119
933093004275	Uncharacterized protein family UPF0016; Region: UPF0016; pfam01169
933093004276	Uncharacterized protein family UPF0016; Region: UPF0016; pfam01169
933093004277	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
933093004278	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
933093004279	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
933093004280	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
933093004281	Chlamydia CHLPS protein (DUF818); Region: DUF818; pfam05677
933093004282	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
933093004283	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
933093004284	threonine synthase; Validated; Region: PRK09225
933093004285	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
933093004286	catalytic residue [active]
933093004287	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
933093004288	YceI-like domain; Region: YceI; pfam04264
933093004289	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
933093004290	YceI-like domain; Region: YceI; smart00867
933093004291	Predicted integral membrane protein (DUF2282); Region: DUF2282; pfam10048
933093004292	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
933093004293	Acetolactate synthase [Amino acid transport and metabolism]; Region: COG3962
933093004294	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
933093004295	PYR/PP interface [polypeptide binding]; other site
933093004296	dimer interface [polypeptide binding]; other site
933093004297	TPP binding site [chemical binding]; other site
933093004298	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
933093004299	Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins similar to Rhizobium leguminosarum bv. viciae IolD. IolD plays an important role in myo-inositol catabolism; Region: TPP_IolD; cd02003
933093004300	TPP-binding site; other site
933093004301	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
933093004302	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
933093004303	substrate binding site [chemical binding]; other site
933093004304	ATP binding site [chemical binding]; other site
933093004305	KduI/IolB family; Region: KduI; pfam04962
933093004306	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
933093004307	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
933093004308	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
933093004309	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093004310	putative substrate translocation pore; other site
933093004311	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
933093004312	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093004313	Zinc metalloprotease (elastase) [Amino acid transport and metabolism]; Region: LasB; COG3227
933093004314	Fungalysin/Thermolysin Propeptide Motif; Region: FTP; pfam07504
933093004315	Peptidase M4 family includes thermolysin, protealysin, aureolysin and neutral protease; Region: M4_neutral_protease; cd09597
933093004316	active site
933093004317	Zn binding site [ion binding]; other site
933093004318	ATP-grasp domain; Region: ATP-grasp_4; cl17255
933093004319	N-Dimethylarginine dimethylaminohydrolase [Amino acid transport and metabolism]; Region: COG1834
933093004320	Amidinotransferase; Region: Amidinotransf; cl12043
933093004321	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
933093004322	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
933093004323	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4299
933093004324	Major Facilitator Superfamily; Region: MFS_1; pfam07690
933093004325	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093004326	putative substrate translocation pore; other site
933093004327	penicillin-binding protein 1C; Region: PBP_1c; TIGR02073
933093004328	Transglycosylase; Region: Transgly; pfam00912
933093004329	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
933093004330	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
933093004331	IgD-like repeat domain of mycobacterial L,D-transpeptidases; Region: LDT_IgD_like; cl17506
933093004332	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
933093004333	MG2 domain; Region: A2M_N; pfam01835
933093004334	Alpha-2-macroglobulin family; Region: A2M; pfam00207
933093004335	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
933093004336	surface patch; other site
933093004337	thioester region; other site
933093004338	specificity defining residues; other site
933093004339	IgA Peptidase M64; Region: Peptidase_M64; pfam09471
933093004340	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
933093004341	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
933093004342	Alpha amylase catalytic domain family; Region: AmyAc_family; cd00551
933093004343	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
933093004344	active site
933093004345	catalytic site [active]
933093004346	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
933093004347	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
933093004348	active site
933093004349	substrate binding site [chemical binding]; other site
933093004350	cosubstrate binding site; other site
933093004351	catalytic site [active]
933093004352	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
933093004353	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
933093004354	ATP-grasp domain; Region: ATP-grasp_4; cl17255
933093004355	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
933093004356	amidophosphoribosyltransferase; Provisional; Region: PRK09246
933093004357	Glutamine amidotransferases class-II (GATase). The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, glutamine is hydrolyzed to glutamic acid and ammonia. This domain is related to...; Region: Gn_AT_II; cl00319
933093004358	active site
933093004359	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
933093004360	active site
933093004361	non-metazoan 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_Sc; cd01414
933093004362	ATP binding site [chemical binding]; other site
933093004363	active site
933093004364	substrate binding site [chemical binding]; other site
933093004365	phosphoribosylformylglycinamidine synthase I; Provisional; Region: PRK03619
933093004366	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
933093004367	putative active site [active]
933093004368	catalytic triad [active]
933093004369	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
933093004370	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
933093004371	dimerization interface [polypeptide binding]; other site
933093004372	putative ATP binding site [chemical binding]; other site
933093004373	phosphoribosylformylglycinamidine synthase II; Provisional; Region: PRK01213
933093004374	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
933093004375	dimerization interface [polypeptide binding]; other site
933093004376	ATP binding site [chemical binding]; other site
933093004377	Mitochondrial ribosomal protein subunit L20; Region: MRP-L20; pfam12824
933093004378	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
933093004379	dimerization interface [polypeptide binding]; other site
933093004380	ATP binding site [chemical binding]; other site
933093004381	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
933093004382	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
933093004383	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
933093004384	DsbD alpha interface [polypeptide binding]; other site
933093004385	catalytic residues [active]
933093004386	short chain dehydrogenase; Provisional; Region: PRK05993
933093004387	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
933093004388	NADP binding site [chemical binding]; other site
933093004389	active site
933093004390	steroid binding site; other site
933093004391	D123; Region: D123; pfam07065
933093004392	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
933093004393	aconitate hydratase; Validated; Region: PRK09277
933093004394	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
933093004395	substrate binding site [chemical binding]; other site
933093004396	ligand binding site [chemical binding]; other site
933093004397	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
933093004398	substrate binding site [chemical binding]; other site
933093004399	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
933093004400	DDE superfamily endonuclease; Region: DDE_3; pfam13358
933093004401	Winged helix-turn helix; Region: HTH_33; pfam13592
933093004402	bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: PRK11904
933093004403	Proline dehydrogenase; Region: Pro_dh; pfam01619
933093004404	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
933093004405	Glutamate binding site [chemical binding]; other site
933093004406	NAD binding site [chemical binding]; other site
933093004407	catalytic residues [active]
933093004408	L,D-transpeptidase catalytic domain; Region: YkuD_2; pfam13645
933093004409	Activator of osmoprotectant transporter ProP [Signal transduction mechanisms]; Region: ProQ; COG3109
933093004410	ProQ/FINO family; Region: ProQ; pfam04352
933093004411	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
933093004412	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
933093004413	S-adenosylmethionine binding site [chemical binding]; other site
933093004414	Uracil-DNA glycosylases (UDG) and related enzymes; Region: UDG_like; cl00483
933093004415	ligand binding site [chemical binding]; other site
933093004416	active site
933093004417	Protein of unknown function (DUF3429); Region: DUF3429; pfam11911
933093004418	cell division protein MukB; Provisional; Region: mukB; PRK04863
933093004419	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
933093004420	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
933093004421	active site
933093004422	DNA binding site [nucleotide binding]
933093004423	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
933093004424	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
933093004425	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
933093004426	Catalytic site [active]
933093004427	hypothetical protein; Provisional; Region: PRK07338
933093004428	M20 Peptidase Glutamate carboxypeptidase, a periplasmic enzyme; Region: M20_CPDG2; cd03885
933093004429	metal binding site [ion binding]; metal-binding site
933093004430	dimer interface [polypeptide binding]; other site
933093004431	Arginine/ornithine N-succinyltransferase beta subunit [Amino acid transport and metabolism]; Region: AstA; COG3138
933093004432	Arginine N-succinyltransferase beta subunit; Region: AstA; pfam04958
933093004433	succinylglutamic semialdehyde dehydrogenase; Reviewed; Region: astD; PRK09457
933093004434	N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095
933093004435	NAD(P) binding site [chemical binding]; other site
933093004436	catalytic residues [active]
933093004437	succinylarginine dihydrolase; Provisional; Region: PRK13281
933093004438	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
933093004439	Cytochrome c; Region: Cytochrom_C; cl11414
933093004440	ribosome recycling factor; Reviewed; Region: frr; PRK00083
933093004441	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
933093004442	hinge region; other site
933093004443	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
933093004444	putative nucleotide binding site [chemical binding]; other site
933093004445	uridine monophosphate binding site [chemical binding]; other site
933093004446	homohexameric interface [polypeptide binding]; other site
933093004447	elongation factor Ts; Provisional; Region: tsf; PRK09377
933093004448	UBA/TS-N domain; Region: UBA; pfam00627
933093004449	Elongation factor TS; Region: EF_TS; pfam00889
933093004450	Elongation factor TS; Region: EF_TS; pfam00889
933093004451	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
933093004452	rRNA interaction site [nucleotide binding]; other site
933093004453	S8 interaction site; other site
933093004454	putative laminin-1 binding site; other site
933093004455	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
933093004456	dimer interface [polypeptide binding]; other site
933093004457	SET domain; Region: SET; pfam00856
933093004458	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
933093004459	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
933093004460	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
933093004461	active site
933093004462	PII uridylyl-transferase; Provisional; Region: glnD; PRK00275
933093004463	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
933093004464	metal binding triad; other site
933093004465	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
933093004466	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
933093004467	Zn2+ binding site [ion binding]; other site
933093004468	Mg2+ binding site [ion binding]; other site
933093004469	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
933093004470	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
933093004471	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
933093004472	nucleoside/Zn binding site; other site
933093004473	dimer interface [polypeptide binding]; other site
933093004474	catalytic motif [active]
933093004475	GMP synthase; Reviewed; Region: guaA; PRK00074
933093004476	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
933093004477	AMP/PPi binding site [chemical binding]; other site
933093004478	candidate oxyanion hole; other site
933093004479	catalytic triad [active]
933093004480	potential glutamine specificity residues [chemical binding]; other site
933093004481	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
933093004482	ATP Binding subdomain [chemical binding]; other site
933093004483	Ligand Binding sites [chemical binding]; other site
933093004484	Dimerization subdomain; other site
933093004485	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
933093004486	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
933093004487	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
933093004488	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
933093004489	active site
933093004490	Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning]; Region: MinD; COG2894
933093004491	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
933093004492	Switch I; other site
933093004493	Switch II; other site
933093004494	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
933093004495	Acyl-CoA dehydrogenase, N-terminal domain; Region: Acyl-CoA_dh_N; pfam02771
933093004496	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
933093004497	active site
933093004498	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
933093004499	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
933093004500	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
933093004501	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
933093004502	Walker A/P-loop; other site
933093004503	ATP binding site [chemical binding]; other site
933093004504	Q-loop/lid; other site
933093004505	ABC transporter signature motif; other site
933093004506	Walker B; other site
933093004507	D-loop; other site
933093004508	H-loop/switch region; other site
933093004509	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
933093004510	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
933093004511	dimer interface [polypeptide binding]; other site
933093004512	conserved gate region; other site
933093004513	putative PBP binding loops; other site
933093004514	ABC-ATPase subunit interface; other site
933093004515	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
933093004516	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
933093004517	dimer interface [polypeptide binding]; other site
933093004518	conserved gate region; other site
933093004519	putative PBP binding loops; other site
933093004520	ABC-ATPase subunit interface; other site
933093004521	PIG3 p53-inducible quinone oxidoreductase; Region: p53_inducible_oxidoreductase; cd05276
933093004522	putative NAD(P)H quinone oxidoreductase, PIG3 family; Region: quinone_pig3; TIGR02824
933093004523	NAD(P) binding site [chemical binding]; other site
933093004524	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
933093004525	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
933093004526	Cl- selectivity filter; other site
933093004527	Cl- binding residues [ion binding]; other site
933093004528	pore gating glutamate residue; other site
933093004529	dimer interface [polypeptide binding]; other site
933093004530	H+/Cl- coupling transport residue; other site
933093004531	anthranilate synthase; Provisional; Region: PRK13566
933093004532	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
933093004533	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
933093004534	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
933093004535	glutamine binding [chemical binding]; other site
933093004536	catalytic triad [active]
933093004537	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
933093004538	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
933093004539	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
933093004540	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
933093004541	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
933093004542	GatB domain; Region: GatB_Yqey; smart00845
933093004543	Autotransporter beta-domain; Region: Autotransporter; smart00869
933093004544	CHASE2 domain; Region: CHASE2; pfam05226
933093004545	Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]; Region: CyaA; COG2114
933093004546	cyclase homology domain; Region: CHD; cd07302
933093004547	nucleotidyl binding site; other site
933093004548	metal binding site [ion binding]; metal-binding site
933093004549	dimer interface [polypeptide binding]; other site
933093004550	FecR protein; Region: FecR; pfam04773
933093004551	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
933093004552	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
933093004553	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cl00528
933093004554	trimerization site [polypeptide binding]; other site
933093004555	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
933093004556	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
933093004557	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
933093004558	catalytic residue [active]
933093004559	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
933093004560	rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: LasT; COG0565
933093004561	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
933093004562	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
933093004563	active site
933093004564	dimerization interface [polypeptide binding]; other site
933093004565	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
933093004566	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
933093004567	tandem repeat interface [polypeptide binding]; other site
933093004568	oligomer interface [polypeptide binding]; other site
933093004569	active site residues [active]
933093004570	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
933093004571	Clp amino terminal domain; Region: Clp_N; pfam02861
933093004572	Clp amino terminal domain; Region: Clp_N; pfam02861
933093004573	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
933093004574	Walker A motif; other site
933093004575	ATP binding site [chemical binding]; other site
933093004576	Walker B motif; other site
933093004577	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
933093004578	arginine finger; other site
933093004579	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
933093004580	Walker A motif; other site
933093004581	ATP binding site [chemical binding]; other site
933093004582	Walker B motif; other site
933093004583	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
933093004584	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
933093004585	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
933093004586	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
933093004587	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
933093004588	TIGR02099 family protein; Region: TIGR02099
933093004589	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
933093004590	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
933093004591	Flagellar FliJ protein; Region: FliJ; pfam02050
933093004592	flagellar protein export ATPase FliI; Region: FliI_clade1; TIGR03496
933093004593	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
933093004594	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
933093004595	Walker A motif/ATP binding site; other site
933093004596	Walker B motif; other site
933093004597	Flagellar assembly protein FliH; Region: FliH; pfam02108
933093004598	flagellar motor switch protein G; Validated; Region: fliG; PRK05686
933093004599	FliG C-terminal domain; Region: FliG_C; pfam01706
933093004600	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
933093004601	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
933093004602	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
933093004603	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK00253
933093004604	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
933093004605	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
933093004606	active site
933093004607	phosphorylation site [posttranslational modification]
933093004608	intermolecular recognition site; other site
933093004609	dimerization interface [polypeptide binding]; other site
933093004610	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
933093004611	Walker A motif; other site
933093004612	ATP binding site [chemical binding]; other site
933093004613	Walker B motif; other site
933093004614	arginine finger; other site
933093004615	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
933093004616	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
933093004617	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
933093004618	putative active site [active]
933093004619	heme pocket [chemical binding]; other site
933093004620	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
933093004621	dimer interface [polypeptide binding]; other site
933093004622	phosphorylation site [posttranslational modification]
933093004623	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
933093004624	ATP binding site [chemical binding]; other site
933093004625	G-X-G motif; other site
933093004626	recombination factor protein RarA; Reviewed; Region: PRK13342
933093004627	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
933093004628	Walker A motif; other site
933093004629	ATP binding site [chemical binding]; other site
933093004630	Walker B motif; other site
933093004631	arginine finger; other site
933093004632	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
933093004633	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
933093004634	Outer membrane lipoprotein carrier protein LolA; Region: LolA; pfam03548
933093004635	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
933093004636	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
933093004637	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
933093004638	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
933093004639	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
933093004640	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
933093004641	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
933093004642	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
933093004643	active site residue [active]
933093004644	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
933093004645	rRNA binding site [nucleotide binding]; other site
933093004646	predicted 30S ribosome binding site; other site
933093004647	peptidase PmbA; Provisional; Region: PRK11040
933093004648	Predicted periplasmic protein [Function unknown]; Region: COG3698
933093004649	Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992
933093004650	Cupin-like domain; Region: Cupin_8; pfam13621
933093004651	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK07207
933093004652	ATP cone domain; Region: ATP-cone; pfam03477
933093004653	ATP cone domain; Region: ATP-cone; pfam03477
933093004654	Class I ribonucleotide reductase; Region: RNR_I; cd01679
933093004655	active site
933093004656	dimer interface [polypeptide binding]; other site
933093004657	catalytic residues [active]
933093004658	effector binding site; other site
933093004659	R2 peptide binding site; other site
933093004660	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
933093004661	dimer interface [polypeptide binding]; other site
933093004662	putative radical transfer pathway; other site
933093004663	diiron center [ion binding]; other site
933093004664	tyrosyl radical; other site
933093004665	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
933093004666	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
933093004667	dimer interface [polypeptide binding]; other site
933093004668	putative anticodon binding site; other site
933093004669	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
933093004670	motif 1; other site
933093004671	active site
933093004672	motif 2; other site
933093004673	motif 3; other site
933093004674	peptide chain release factor 2; Validated; Region: prfB; PRK00578
933093004675	This domain is found in peptide chain release factors; Region: PCRF; smart00937
933093004676	RF-1 domain; Region: RF-1; pfam00472
933093004677	Protein of unknown function (DUF2802); Region: DUF2802; pfam10975
933093004678	flagellar motor protein MotD; Reviewed; Region: PRK09038
933093004679	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
933093004680	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
933093004681	ligand binding site [chemical binding]; other site
933093004682	flagellar motor protein; Reviewed; Region: motC; PRK09109
933093004683	flagellar motor protein MotA; Validated; Region: PRK08124
933093004684	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
933093004685	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
933093004686	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
933093004687	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
933093004688	DNA binding residues [nucleotide binding]
933093004689	Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]; Region: flhG; COG0455
933093004690	FleN is a member of the Fer4_NifH superfamily. It shares the common function as an ATPase, with the ATP-binding domain at the N-terminus. In Pseudomonas aeruginosa, FleN gene is involved in regulating the number of flagella and chemotactic motility by...; Region: FleN-like; cd02038
933093004691	P-loop; other site
933093004692	FleN is a member of the Fer4_NifH superfamily. It shares the common function as an ATPase, with the ATP-binding domain at the N-terminus. In Pseudomonas aeruginosa, FleN gene is involved in regulating the number of flagella and chemotactic motility by...; Region: FleN-like; cd02038
933093004693	flagellar biosynthesis regulator FlhF; Validated; Region: flhF; PRK05703
933093004694	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
933093004695	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
933093004696	FHIPEP family; Region: FHIPEP; pfam00771
933093004697	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
933093004698	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
933093004699	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
933093004700	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
933093004701	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
933093004702	Flagellar biosynthesis protein, FliO; Region: FliO; pfam04347
933093004703	Surface presentation of antigens (SPOA); Region: SpoA; cl00819
933093004704	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
933093004705	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
933093004706	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
933093004707	FAD binding domain; Region: FAD_binding_4; pfam01565
933093004708	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
933093004709	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
933093004710	NAD(P) binding site [chemical binding]; other site
933093004711	active site
933093004712	Transcriptional regulator [Transcription]; Region: LysR; COG0583
933093004713	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
933093004714	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
933093004715	dimerization interface [polypeptide binding]; other site
933093004716	chromosome segregation protein SMC, primarily archaeal type; Region: SMC_prok_A; TIGR02169
933093004717	RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when...; Region: RhoGAP; cl02570
933093004718	GTPase interaction site; other site
933093004719	catalytic residue [active]
933093004720	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
933093004721	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
933093004722	motif 1; other site
933093004723	active site
933093004724	motif 2; other site
933093004725	motif 3; other site
933093004726	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
933093004727	recombination regulator RecX; Reviewed; Region: recX; PRK00117
933093004728	recombinase A; Provisional; Region: recA; PRK09354
933093004729	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
933093004730	hexamer interface [polypeptide binding]; other site
933093004731	Walker A motif; other site
933093004732	ATP binding site [chemical binding]; other site
933093004733	Walker B motif; other site
933093004734	Competence-damaged protein; Region: CinA; pfam02464
933093004735	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
933093004736	MutS domain I; Region: MutS_I; pfam01624
933093004737	MutS domain II; Region: MutS_II; pfam05188
933093004738	MutS domain III; Region: MutS_III; pfam05192
933093004739	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
933093004740	Walker A/P-loop; other site
933093004741	ATP binding site [chemical binding]; other site
933093004742	Q-loop/lid; other site
933093004743	ABC transporter signature motif; other site
933093004744	Walker B; other site
933093004745	D-loop; other site
933093004746	H-loop/switch region; other site
933093004747	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
933093004748	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
933093004749	Surface antigen; Region: Bac_surface_Ag; pfam01103
933093004750	Family of unknown function (DUF490); Region: DUF490; pfam04357
933093004751	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
933093004752	dimer interface [polypeptide binding]; other site
933093004753	active site
933093004754	Schiff base residues; other site
933093004755	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
933093004756	bifunctional aspartate kinase/diaminopimelate decarboxylase protein; Provisional; Region: PRK08961
933093004757	AAK_AK-DapDC: Amino Acid Kinase Superfamily (AAK), AK-DapDC; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the bifunctional enzyme AK - DAP decarboxylase (DapDC) found in some bacteria. Aspartokinase is the first enzyme in the...; Region: AAK_AK-DapDC; cd04259
933093004758	putative catalytic residues [active]
933093004759	putative nucleotide binding site [chemical binding]; other site
933093004760	putative aspartate binding site [chemical binding]; other site
933093004761	ACT domains of a bifunctional AKIII (LysC)-like aspartokinase/meso-diaminopimelate decarboxylase (DAPDC) bacterial protein; Region: ACT_AKiii-DAPDC_1; cd04935
933093004762	ACT domains of a bifunctional AKIII (LysC)-like aspartokinase/meso-diaminopimelate decarboxylase (DAPDC); Region: ACT_AKiii-DAPDC_2; cd04920
933093004763	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Bifunctional Aspartate Kinase/Diaminopimelate Decarboxylase; Region: PLPDE_III_Bif_AspK_DapDC; cd06840
933093004764	active site
933093004765	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
933093004766	substrate binding site [chemical binding]; other site
933093004767	catalytic residues [active]
933093004768	dimer interface [polypeptide binding]; other site
933093004769	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) [DNA replication, recombination, and repair]; Region: RecB; COG1074
933093004770	Part of AAA domain; Region: AAA_19; pfam13245
933093004771	Family description; Region: UvrD_C_2; pfam13538
933093004772	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cl00641
933093004773	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
933093004774	Protein of unknown function (DUF2803); Region: DUF2803; pfam10972
933093004775	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
933093004776	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
933093004777	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
933093004778	dimerization interface [polypeptide binding]; other site
933093004779	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093004780	Major Facilitator Superfamily; Region: MFS_1; pfam07690
933093004781	putative substrate translocation pore; other site
933093004782	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
933093004783	Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663
933093004784	lipid A export permease/ATP-binding protein MsbA; Region: MsbA_lipidA; TIGR02203
933093004785	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
933093004786	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
933093004787	Walker A/P-loop; other site
933093004788	ATP binding site [chemical binding]; other site
933093004789	Q-loop/lid; other site
933093004790	ABC transporter signature motif; other site
933093004791	Walker B; other site
933093004792	D-loop; other site
933093004793	H-loop/switch region; other site
933093004794	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
933093004795	Coenzyme A binding pocket [chemical binding]; other site
933093004796	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
933093004797	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
933093004798	quinone interaction residues [chemical binding]; other site
933093004799	active site
933093004800	catalytic residues [active]
933093004801	FMN binding site [chemical binding]; other site
933093004802	substrate binding site [chemical binding]; other site
933093004803	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
933093004804	isovaleryl-CoA dehydrogenase; Region: PLN02519
933093004805	Isovaleryl-CoA dehydrogenase; Region: IVD; cd01156
933093004806	substrate binding site [chemical binding]; other site
933093004807	FAD binding site [chemical binding]; other site
933093004808	catalytic base [active]
933093004809	acetyl-CoA acetyltransferase; Provisional; Region: PRK06954
933093004810	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
933093004811	dimer interface [polypeptide binding]; other site
933093004812	active site
933093004813	3-methylcrotonyl-CoA carboxylase, beta chain; Region: PLN02820
933093004814	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
933093004815	enoyl-CoA hydratase; Provisional; Region: PRK05995
933093004816	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
933093004817	substrate binding site [chemical binding]; other site
933093004818	oxyanion hole (OAH) forming residues; other site
933093004819	trimer interface [polypeptide binding]; other site
933093004820	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cl15762
933093004821	Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism]; Region: COG4770
933093004822	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
933093004823	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
933093004824	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
933093004825	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
933093004826	carboxyltransferase (CT) interaction site; other site
933093004827	biotinylation site [posttranslational modification]; other site
933093004828	Isopropylmalate/homocitrate/citramalate synthases [Amino acid transport and metabolism]; Region: LeuA; COG0119
933093004829	3-hydroxy-3-methylglutaryl-CoA lyase, catalytic TIM barrel domain; Region: DRE_TIM_HMGL; cd07938
933093004830	active site
933093004831	catalytic residues [active]
933093004832	metal binding site [ion binding]; metal-binding site
933093004833	acetoacetyl-CoA synthetase; Provisional; Region: PRK03584
933093004834	Acetoacetyl-CoA synthetase (acetoacetate-CoA ligase, AACS); Region: AACS; cd05943
933093004835	acyl-activating enzyme (AAE) consensus motif; other site
933093004836	putative AMP binding site [chemical binding]; other site
933093004837	putative active site [active]
933093004838	putative CoA binding site [chemical binding]; other site
933093004839	VirK protein; Region: VirK; pfam06903
933093004840	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
933093004841	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
933093004842	Walker A/P-loop; other site
933093004843	ATP binding site [chemical binding]; other site
933093004844	Q-loop/lid; other site
933093004845	ABC transporter signature motif; other site
933093004846	Walker B; other site
933093004847	D-loop; other site
933093004848	H-loop/switch region; other site
933093004849	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
933093004850	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
933093004851	dimer interface [polypeptide binding]; other site
933093004852	conserved gate region; other site
933093004853	ABC-ATPase subunit interface; other site
933093004854	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
933093004855	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
933093004856	Putative SAM-dependent methyltransferase; Region: SAM_MT; cl17517
933093004857	D,D-heptose 1,7-bisphosphate phosphatase; Validated; Region: PRK08942
933093004858	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
933093004859	active site
933093004860	motif I; other site
933093004861	motif II; other site
933093004862	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
933093004863	DALR anticodon binding domain; Region: DALR_1; pfam05746
933093004864	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
933093004865	dimer interface [polypeptide binding]; other site
933093004866	motif 1; other site
933093004867	active site
933093004868	motif 2; other site
933093004869	motif 3; other site
933093004870	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
933093004871	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
933093004872	catalytic residues [active]
933093004873	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
933093004874	Part of AAA domain; Region: AAA_19; pfam13245
933093004875	Family description; Region: UvrD_C_2; pfam13538
933093004876	proline iminopeptidase, Neisseria-type subfamily; Region: pro_imino_pep_1; TIGR01249
933093004877	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
933093004878	putative active site [active]
933093004879	dimerization interface [polypeptide binding]; other site
933093004880	putative tRNAtyr binding site [nucleotide binding]; other site
933093004881	VacJ like lipoprotein; Region: VacJ; cl01073
933093004882	glutathione synthetase; Provisional; Region: PRK05246
933093004883	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
933093004884	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
933093004885	Glutamate-cysteine ligase; Region: GshA; pfam08886
933093004886	glutamate--cysteine ligase, T. ferrooxidans family; Region: gshA_ferroox; TIGR02049
933093004887	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
933093004888	EamA-like transporter family; Region: EamA; pfam00892
933093004889	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
933093004890	active site residue [active]
933093004891	Type I phosphodiesterase / nucleotide pyrophosphatase; Region: Phosphodiest; pfam01663
933093004892	PglZ domain; Region: PglZ; pfam08665
933093004893	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
933093004894	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
933093004895	Sugar specificity; other site
933093004896	Pyrimidine base specificity; other site
933093004897	ATP-binding site [chemical binding]; other site
933093004898	Enoyl-[acyl-carrier-protein]; Region: FabI; COG0623
933093004899	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
933093004900	NAD binding site [chemical binding]; other site
933093004901	homotetramer interface [polypeptide binding]; other site
933093004902	homodimer interface [polypeptide binding]; other site
933093004903	substrate binding site [chemical binding]; other site
933093004904	active site
933093004905	periplasmic folding chaperone; Provisional; Region: PRK10788
933093004906	SurA N-terminal domain; Region: SurA_N_3; cl07813
933093004907	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
933093004908	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
933093004909	IHF dimer interface [polypeptide binding]; other site
933093004910	IHF - DNA interface [nucleotide binding]; other site
933093004911	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
933093004912	Found in ATP-dependent protease La (LON); Region: LON; smart00464
933093004913	Found in ATP-dependent protease La (LON); Region: LON; smart00464
933093004914	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
933093004915	Walker A motif; other site
933093004916	ATP binding site [chemical binding]; other site
933093004917	Walker B motif; other site
933093004918	arginine finger; other site
933093004919	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
933093004920	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
933093004921	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
933093004922	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
933093004923	Walker A motif; other site
933093004924	ATP binding site [chemical binding]; other site
933093004925	Walker B motif; other site
933093004926	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
933093004927	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
933093004928	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
933093004929	oligomer interface [polypeptide binding]; other site
933093004930	active site residues [active]
933093004931	trigger factor; Provisional; Region: tig; PRK01490
933093004932	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
933093004933	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
933093004934	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
933093004935	INT_SG1, DNA breaking-rejoining enzymes, integrase/recombinases subgroup 1, C-terminal catalytic domain. The CD contains mainly predicted integrase/recombinase and site-specific XerD recombinases. The members of this CD are found predominantly in...; Region: INT_SG1_C; cd01183
933093004936	Int/Topo IB signature motif; other site
933093004937	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
933093004938	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
933093004939	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
933093004940	ABC transporter; Region: ABC_tran_2; pfam12848
933093004941	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
933093004942	ribonuclease III; Reviewed; Region: rnc; PRK00102
933093004943	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
933093004944	dimerization interface [polypeptide binding]; other site
933093004945	active site
933093004946	metal binding site [ion binding]; metal-binding site
933093004947	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
933093004948	dsRNA binding site [nucleotide binding]; other site
933093004949	Tfp pilus assembly protein PilE [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilE; COG4968
933093004950	signal peptidase I; Provisional; Region: PRK10861
933093004951	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
933093004952	Catalytic site [active]
933093004953	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
933093004954	GTP-binding protein LepA; Provisional; Region: PRK05433
933093004955	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
933093004956	G1 box; other site
933093004957	putative GEF interaction site [polypeptide binding]; other site
933093004958	GTP/Mg2+ binding site [chemical binding]; other site
933093004959	Switch I region; other site
933093004960	G2 box; other site
933093004961	G3 box; other site
933093004962	Switch II region; other site
933093004963	G4 box; other site
933093004964	G5 box; other site
933093004965	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
933093004966	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
933093004967	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
933093004968	Transglycosylase SLT domain; Region: SLT_2; pfam13406
933093004969	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
933093004970	N-acetyl-D-glucosamine binding site [chemical binding]; other site
933093004971	type II secretion system protein L; Region: typeII_sec_gspL; TIGR01709
933093004972	Type II secretion system (T2SS), protein L; Region: T2SL; pfam05134
933093004973	GspL periplasmic domain; Region: GspL_C; cl14909
933093004974	Type II secretion system (T2SS), protein M; Region: T2SM; pfam04612
933093004975	Sporulation related domain; Region: SPOR; cl10051
933093004976	deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK05318
933093004977	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
933093004978	Zn2+ binding site [ion binding]; other site
933093004979	Mg2+ binding site [ion binding]; other site
933093004980	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
933093004981	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
933093004982	dimer interface [polypeptide binding]; other site
933093004983	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
933093004984	active site
933093004985	metal binding site [ion binding]; metal-binding site
933093004986	glutathione binding site [chemical binding]; other site
933093004987	hypothetical protein; Provisional; Region: PRK05208
933093004988	JNK_SAPK-associated protein-1; Region: Jnk-SapK_ap_N; pfam09744
933093004989	Immune inhibitor A peptidase M6; Region: Peptidase_M6; cl11525
933093004990	acylphosphatase; Provisional; Region: PRK14451
933093004991	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
933093004992	putative active site [active]
933093004993	catalytic site [active]
933093004994	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
933093004995	PLD-like domain; Region: PLDc_2; pfam13091
933093004996	putative active site [active]
933093004997	catalytic site [active]
933093004998	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
933093004999	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
933093005000	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
933093005001	Leucine-rich repeats; other site
933093005002	Substrate binding site [chemical binding]; other site
933093005003	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
933093005004	Leucine-rich repeats; other site
933093005005	Leucine rich repeat; Region: LRR_8; pfam13855
933093005006	Substrate binding site [chemical binding]; other site
933093005007	SH3 domain protein; Region: SH3_and_anchor; TIGR04211
933093005008	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093005009	D-galactonate transporter; Region: 2A0114; TIGR00893
933093005010	putative substrate translocation pore; other site
933093005011	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
933093005012	Putative ClC chloride channel.  Clc proteins are putative halogen ion (Cl-, Br- and I-) transporters found in eubacteria. They belong to the ClC superfamily of halogen ion channels, which share a unique double-barreled architecture and voltage-dependent...; Region: ClC_like; cd01033
933093005013	putative ion selectivity filter; other site
933093005014	putative pore gating glutamate residue; other site
933093005015	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3012
933093005016	SEC-C motif; Region: SEC-C; pfam02810
933093005017	glutathione-regulated potassium-efflux system protein KefC; Provisional; Region: PRK03562
933093005018	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
933093005019	TrkA-N domain; Region: TrkA_N; pfam02254
933093005020	MoxR-like ATPases [General function prediction only]; Region: COG0714
933093005021	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
933093005022	Walker A motif; other site
933093005023	ATP binding site [chemical binding]; other site
933093005024	Walker B motif; other site
933093005025	arginine finger; other site
933093005026	Protein of unknown function DUF58; Region: DUF58; pfam01882
933093005027	Domain of unknown function (DUF3488); Region: DUF3488; pfam11992
933093005028	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
933093005029	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
933093005030	Uncharacterized conserved protein [Function unknown]; Region: COG2850
933093005031	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
933093005032	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
933093005033	EamA-like transporter family; Region: EamA; pfam00892
933093005034	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
933093005035	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
933093005036	nucleotide binding site [chemical binding]; other site
933093005037	Protein of unknown function, DUF462; Region: DUF462; pfam04315
933093005038	glutathionine S-transferase; Provisional; Region: PRK10542
933093005039	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
933093005040	C-terminal domain interface [polypeptide binding]; other site
933093005041	GSH binding site (G-site) [chemical binding]; other site
933093005042	dimer interface [polypeptide binding]; other site
933093005043	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
933093005044	N-terminal domain interface [polypeptide binding]; other site
933093005045	dimer interface [polypeptide binding]; other site
933093005046	substrate binding pocket (H-site) [chemical binding]; other site
933093005047	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
933093005048	Beta-lactamase; Region: Beta-lactamase; pfam00144
933093005049	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
933093005050	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
933093005051	HIGH motif; other site
933093005052	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
933093005053	active site
933093005054	KMSKS motif; other site
933093005055	hybrid sensory histidine kinase BarA; Provisional; Region: PRK11107
933093005056	HAMP domain; Region: HAMP; pfam00672
933093005057	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
933093005058	dimer interface [polypeptide binding]; other site
933093005059	phosphorylation site [posttranslational modification]
933093005060	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
933093005061	ATP binding site [chemical binding]; other site
933093005062	Mg2+ binding site [ion binding]; other site
933093005063	G-X-G motif; other site
933093005064	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
933093005065	active site
933093005066	phosphorylation site [posttranslational modification]
933093005067	intermolecular recognition site; other site
933093005068	dimerization interface [polypeptide binding]; other site
933093005069	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
933093005070	putative binding surface; other site
933093005071	active site
933093005072	6-phosphofructokinase; Provisional; Region: PRK14072
933093005073	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
933093005074	active site
933093005075	ADP/pyrophosphate binding site [chemical binding]; other site
933093005076	dimerization interface [polypeptide binding]; other site
933093005077	allosteric effector site; other site
933093005078	fructose-1,6-bisphosphate binding site; other site
933093005079	Tfp pilus assembly protein, major pilin PilA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilA; COG4969
933093005080	Pilin (bacterial filament); Region: Pilin; pfam00114
933093005081	Tfp pilus assembly protein, major pilin PilA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilA; COG4969
933093005082	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830
933093005083	Pilin (bacterial filament); Region: Pilin; pfam00114
933093005084	BolA-like protein; Region: BolA; cl00386
933093005085	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
933093005086	Calcium-activated chloride channel; Region: Anoctamin; pfam04547
933093005087	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
933093005088	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
933093005089	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
933093005090	Ligand binding site; other site
933093005091	oligomer interface; other site
933093005092	Uncharacterized conserved protein [Function unknown]; Region: COG2835
933093005093	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
933093005094	Glycoprotease family; Region: Peptidase_M22; pfam00814
933093005095	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
933093005096	DEAD/DEAH box helicase; Region: DEAD; pfam00270
933093005097	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
933093005098	Ferredoxin [Energy production and conversion]; Region: COG1146
933093005099	4Fe-4S binding domain; Region: Fer4; cl02805
933093005100	Domain of unknown function (DUF3470); Region: DUF3470; pfam11953
933093005101	HipA-like N-terminal domain; Region: HipA_N; pfam07805
933093005102	PilZ domain; Region: PilZ; pfam07238
933093005103	oxidative damage protection protein; Provisional; Region: PRK05408
933093005104	Indigoidine synthase A like protein; Region: Indigoidine_A; pfam04227
933093005105	HipA N-terminal domain; Region: Couple_hipA; pfam13657
933093005106	HipA-like N-terminal domain; Region: HipA_N; pfam07805
933093005107	HipA-like C-terminal domain; Region: HipA_C; pfam07804
933093005108	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
933093005109	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
933093005110	non-specific DNA binding site [nucleotide binding]; other site
933093005111	salt bridge; other site
933093005112	sequence-specific DNA binding site [nucleotide binding]; other site
933093005113	methyltransferase, FkbM family; Region: fkbM_fam; TIGR01444
933093005114	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
933093005115	S-adenosylmethionine binding site [chemical binding]; other site
933093005116	Taurine catabolism dioxygenase TauD, TfdA family; Region: TauD; pfam02668
933093005117	putative adenylate-forming enzyme; Region: aden_form_hyp; TIGR02304
933093005118	Coenzyme F390 synthetase [Coenzyme metabolism]; Region: PaaK; COG1541
933093005119	3-oxoacyl-(acyl-carrier-protein) synthase [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: FabB; COG0304
933093005120	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
933093005121	active site
933093005122	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
933093005123	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
933093005124	acyl-activating enzyme (AAE) consensus motif; other site
933093005125	AMP binding site [chemical binding]; other site
933093005126	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
933093005127	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
933093005128	active site
933093005129	3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]; Region: FadB; COG1250
933093005130	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
933093005131	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
933093005132	Phosphopantetheine attachment site; Region: PP-binding; cl09936
933093005133	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
933093005134	Hypothetical patatin similar to Z1214 protein of Escherichia coli; Region: Pat_hypo_Ecoli_Z1214_like; cd07209
933093005135	active site
933093005136	nucleophile elbow; other site
933093005137	Patatin phospholipase; Region: DUF3734; pfam12536
933093005138	cAMP phosphodiesterases class-II; Region: PDEase_II; cl17776
933093005139	PAS fold; Region: PAS_4; pfam08448
933093005140	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
933093005141	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
933093005142	DNA binding residues [nucleotide binding]
933093005143	dimerization interface [polypeptide binding]; other site
933093005144	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
933093005145	Leucine-rich repeats; other site
933093005146	Substrate binding site [chemical binding]; other site
933093005147	Sec7 domain; Domain named after the S. cerevisiae SEC7 gene product. The Sec7 domain is the central domain of the guanine-nucleotide-exchange factors (GEFs) of the ADP-ribosylation factor family of small GTPases (ARFs) . It carries the exchange factor...; Region: Sec7; cd00171
933093005148	active site/putative ARF binding site [active]
933093005149	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
933093005150	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
933093005151	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
933093005152	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
933093005153	active site
933093005154	metal binding site [ion binding]; metal-binding site
933093005155	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
933093005156	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
933093005157	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
933093005158	active site
933093005159	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
933093005160	Leucine-rich repeats; other site
933093005161	Substrate binding site [chemical binding]; other site
933093005162	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
933093005163	Glycosyltransferase sugar-binding region containing DXD motif; Region: Gly_transf_sug; pfam04488
933093005164	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
933093005165	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
933093005166	active site
933093005167	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
933093005168	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
933093005169	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
933093005170	GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972
933093005171	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
933093005172	C-terminal domain interface [polypeptide binding]; other site
933093005173	GSH binding site (G-site) [chemical binding]; other site
933093005174	dimer interface [polypeptide binding]; other site
933093005175	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776
933093005176	N-terminal domain interface [polypeptide binding]; other site
933093005177	dimer interface [polypeptide binding]; other site
933093005178	substrate binding pocket (H-site) [chemical binding]; other site
933093005179	peroxiredoxin, Ohr subfamily; Region: organ_hyd_perox; TIGR03561
933093005180	Legionella pneumophila major outer membrane protein precursor; Region: Legionella_OMP; pfam05150
933093005181	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
933093005182	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
933093005183	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
933093005184	intracellular protease, PfpI family; Region: PfpI; TIGR01382
933093005185	Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_1; cd03169
933093005186	conserved cys residue [active]
933093005187	Glycosyltransferase sugar-binding region containing DXD motif; Region: Gly_transf_sug; pfam04488
933093005188	TPR repeat; Region: TPR_11; pfam13414
933093005189	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
933093005190	binding surface
933093005191	TPR motif; other site
933093005192	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
933093005193	substrate binding site [chemical binding]; other site
933093005194	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
933093005195	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
933093005196	active site
933093005197	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
933093005198	Toprim domain; Region: Toprim_3; pfam13362
933093005199	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
933093005200	catalytic core [active]
933093005201	RibD C-terminal domain; Region: RibD_C; cl17279
933093005202	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
933093005203	MAPEG family; Region: MAPEG; cl09190
933093005204	YhhN-like protein; Region: YhhN; pfam07947
933093005205	Catalytic NodB homology domain of uncharacterized bacterial polysaccharide deacetylases; Region: CE4_NodB_like_1; cd10960
933093005206	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
933093005207	NodB motif; other site
933093005208	putative active site [active]
933093005209	putative catalytic site [active]
933093005210	putative Zn binding site [ion binding]; other site
933093005211	Membrane-bound lytic murein transglycosylase [Cell envelope biogenesis, outer membrane]; Region: MltA; COG2821
933093005212	MltA specific insert domain; Region: MltA; pfam03562
933093005213	3D domain; Region: 3D; pfam06725
933093005214	Tfp pilus assembly protein PilW [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilW; COG4966
933093005215	histidinol-phosphate aminotransferase; Validated; Region: PRK02731
933093005216	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
933093005217	pyridoxal 5'-phosphate binding site [chemical binding]; other site
933093005218	homodimer interface [polypeptide binding]; other site
933093005219	catalytic residue [active]
933093005220	PCD_DCoH: The bifunctional protein pterin-4alpha-carbinolamine dehydratase (PCD), also known as DCoH  (dimerization cofactor of hepatocyte nuclear factor-1), is both a transcription activator and a metabolic enzyme.  DCoH stimulates gene expression by...; Region: PCD_DCoH_subfamily_a; cd00913
933093005221	aromatic arch; other site
933093005222	DCoH dimer interaction site [polypeptide binding]; other site
933093005223	DCoH /HNF-1 dimer interaction site [polypeptide binding]; other site
933093005224	DCoH tetramer interaction site [polypeptide binding]; other site
933093005225	substrate binding site [chemical binding]; other site
933093005226	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
933093005227	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
933093005228	Protein export membrane protein; Region: SecD_SecF; pfam02355
933093005229	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
933093005230	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
933093005231	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
933093005232	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
933093005233	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; cl00409
933093005234	Queuosine biosynthesis protein; Region: Queuosine_synth; pfam02547
933093005235	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
933093005236	ABC transporter ATPase component; Reviewed; Region: PRK11147
933093005237	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
933093005238	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
933093005239	ABC transporter; Region: ABC_tran_2; pfam12848
933093005240	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
933093005241	Bacterial aspartate proteases, retropepsin-like protease family; Region: retropepsin_like_bacteria; cd05483
933093005242	catalytic motif [active]
933093005243	Catalytic residue [active]
933093005244	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
933093005245	homotrimer interaction site [polypeptide binding]; other site
933093005246	putative active site [active]
933093005247	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
933093005248	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
933093005249	Zn2+ binding site [ion binding]; other site
933093005250	Mg2+ binding site [ion binding]; other site
933093005251	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
933093005252	synthetase active site [active]
933093005253	NTP binding site [chemical binding]; other site
933093005254	metal binding site [ion binding]; metal-binding site
933093005255	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
933093005256	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
933093005257	DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392
933093005258	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
933093005259	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
933093005260	catalytic site [active]
933093005261	G-X2-G-X-G-K; other site
933093005262	hypothetical protein; Provisional; Region: PRK11820
933093005263	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
933093005264	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
933093005265	ribonuclease PH; Reviewed; Region: rph; PRK00173
933093005266	Ribonuclease PH; Region: RNase_PH_bact; cd11362
933093005267	hexamer interface [polypeptide binding]; other site
933093005268	active site
933093005269	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
933093005270	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
933093005271	Walker A motif; other site
933093005272	ATP binding site [chemical binding]; other site
933093005273	Walker B motif; other site
933093005274	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
933093005275	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
933093005276	catalytic residue [active]
933093005277	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
933093005278	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
933093005279	YGGT family; Region: YGGT; pfam02325
933093005280	Protein of unknown function (DUF2845); Region: DUF2845; pfam11006
933093005281	Protein of unknown function (DUF2845); Region: DUF2845; pfam11006
933093005282	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
933093005283	active site
933093005284	catalytic residues [active]
933093005285	Arabinose-binding domain of AraC transcription regulator, N-term; Region: Arabinose_bd; pfam12625
933093005286	Helix-turn-helix domain; Region: HTH_18; pfam12833
933093005287	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
933093005288	S-adenosyl-L-homocysteine hydrolase; Provisional; Region: PRK05476
933093005289	S-Adenosylhomocysteine Hydrolase, NAD-binding and catalytic domains; Region: SAHH; cd00401
933093005290	homotetramer interface [polypeptide binding]; other site
933093005291	ligand binding site [chemical binding]; other site
933093005292	catalytic site [active]
933093005293	NAD binding site [chemical binding]; other site
933093005294	S-adenosylmethionine synthetase; Validated; Region: PRK05250
933093005295	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
933093005296	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
933093005297	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
933093005298	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
933093005299	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
933093005300	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
933093005301	catalytic site [active]
933093005302	subunit interface [polypeptide binding]; other site
933093005303	chaperone protein DnaJ; Provisional; Region: PRK10767
933093005304	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
933093005305	HSP70 interaction site [polypeptide binding]; other site
933093005306	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
933093005307	substrate binding site [polypeptide binding]; other site
933093005308	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
933093005309	Zn binding sites [ion binding]; other site
933093005310	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
933093005311	dimer interface [polypeptide binding]; other site
933093005312	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
933093005313	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
933093005314	nucleotide binding site [chemical binding]; other site
933093005315	GrpE; Region: GrpE; pfam01025
933093005316	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
933093005317	dimer interface [polypeptide binding]; other site
933093005318	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
933093005319	Class-II DAHP synthetase family; Region: DAHP_synth_2; pfam01474
933093005320	methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252
933093005321	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
933093005322	substrate binding site [chemical binding]; other site
933093005323	active site
933093005324	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
933093005325	homooctamer interface [polypeptide binding]; other site
933093005326	active site
933093005327	Uncharacterized protein conserved in bacteria [Function unknown]; Region: DedD; COG3147
933093005328	Sporulation related domain; Region: SPOR; pfam05036
933093005329	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
933093005330	Arginyl tRNA synthetase N terminal domain; Region: Arg_tRNA_synt_N; pfam03485
933093005331	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
933093005332	active site
933093005333	HIGH motif; other site
933093005334	nucleotide binding site [chemical binding]; other site
933093005335	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
933093005336	KMSK motif region; other site
933093005337	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
933093005338	tRNA binding surface [nucleotide binding]; other site
933093005339	anticodon binding site; other site
933093005340	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
933093005341	Domain of unknown function DUF20; Region: UPF0118; pfam01594
933093005342	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
933093005343	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
933093005344	generic binding surface II; other site
933093005345	ssDNA binding site; other site
933093005346	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
933093005347	ATP binding site [chemical binding]; other site
933093005348	putative Mg++ binding site [ion binding]; other site
933093005349	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
933093005350	nucleotide binding region [chemical binding]; other site
933093005351	ATP-binding site [chemical binding]; other site
933093005352	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
933093005353	cation diffusion facilitator family transporter; Region: CDF; TIGR01297
933093005354	Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]; Region: COG0428; cl00437
933093005355	ZIP Zinc transporter; Region: Zip; pfam02535
933093005356	Maf-like protein; Region: Maf; pfam02545
933093005357	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
933093005358	active site
933093005359	dimer interface [polypeptide binding]; other site
933093005360	enolase; Provisional; Region: eno; PRK00077
933093005361	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
933093005362	dimer interface [polypeptide binding]; other site
933093005363	metal binding site [ion binding]; metal-binding site
933093005364	substrate binding pocket [chemical binding]; other site
933093005365	Septum formation initiator; Region: DivIC; cl17659
933093005366	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
933093005367	mevalonate kinase; Region: mevalon_kin; TIGR00549
933093005368	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
933093005369	Mevalonate pyrophosphate decarboxylase [Lipid metabolism]; Region: MVD1; COG3407
933093005370	diphosphomevalonate decarboxylase; Region: PLN02407
933093005371	diphosphomevalonate decarboxylase; Region: PLN02407
933093005372	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE, gammaproteobacterial type; Region: rSAM_QueE_gams; TIGR04349
933093005373	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
933093005374	FeS/SAM binding site; other site
933093005375	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
933093005376	binding surface
933093005377	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
933093005378	TPR motif; other site
933093005379	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
933093005380	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
933093005381	ligand binding site [chemical binding]; other site
933093005382	Protein of unknown function (DUF330); Region: DUF330; cl01135
933093005383	virulence factor Mce family protein; Region: Mtu_fam_mce; TIGR00996
933093005384	mce related protein; Region: MCE; pfam02470
933093005385	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
933093005386	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
933093005387	Walker A/P-loop; other site
933093005388	ATP binding site [chemical binding]; other site
933093005389	Q-loop/lid; other site
933093005390	ABC transporter signature motif; other site
933093005391	Walker B; other site
933093005392	D-loop; other site
933093005393	H-loop/switch region; other site
933093005394	Sulphate Transporter and Anti-Sigma factor antagonist domain found in the C-terminal region of sulphate transporters as well as in bacterial and archaeal proteins involved in the regulation of sigma factors; Region: STAS; cl00604
933093005395	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
933093005396	Permease; Region: Permease; pfam02405
933093005397	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
933093005398	active site
933093005399	ATP binding site [chemical binding]; other site
933093005400	isopentenyl pyrophosphate isomerase; Provisional; Region: PRK05437
933093005401	Isopentenyl-diphosphate:dimethylallyl diphosphate isomerase type 2 (IDI-2) FMN-binding domain. Two types of IDIs have been characterized at present. The long known IDI-1 is only dependent on divalent metals for activity, whereas IDI-2 requires a metal; Region: IDI-2_FMN; cd02811
933093005402	homotetramer interface [polypeptide binding]; other site
933093005403	FMN binding site [chemical binding]; other site
933093005404	homodimer contacts [polypeptide binding]; other site
933093005405	putative active site [active]
933093005406	putative substrate binding site [chemical binding]; other site
933093005407	Class II hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR); Region: HMG-CoA_reductase_classII; cd00644
933093005408	homodimer interface [polypeptide binding]; other site
933093005409	catalytic residues [active]
933093005410	NAD binding site [chemical binding]; other site
933093005411	substrate binding pocket [chemical binding]; other site
933093005412	flexible flap; other site
933093005413	Mevalonate kinase [Lipid metabolism]; Region: ERG12; COG1577
933093005414	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
933093005415	active site
933093005416	DNA binding site [nucleotide binding]
933093005417	Int/Topo IB signature motif; other site
933093005418	DNA binding domain, excisionase family; Region: excise; TIGR01764
933093005419	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
933093005420	non-specific DNA binding site [nucleotide binding]; other site
933093005421	salt bridge; other site
933093005422	sequence-specific DNA binding site [nucleotide binding]; other site
933093005423	The S24, S26 LexA/signal peptidase superfamily contains LexA-related and type I signal peptidase families. The S24 LexA protein domains include: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the...; Region: Peptidase_S24_S26; cd06462
933093005424	Catalytic site [active]
933093005425	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093005426	Major Facilitator Superfamily; Region: MFS_1; pfam07690
933093005427	putative substrate translocation pore; other site
933093005428	Tetrapyrrole (Corrin/Porphyrin) Methylases; Region: TP_methylase; pfam00590
933093005429	active site
933093005430	SAM binding site [chemical binding]; other site
933093005431	homodimer interface [polypeptide binding]; other site
933093005432	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
933093005433	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones]; Region: ATM1; COG5265
933093005434	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
933093005435	Walker A/P-loop; other site
933093005436	ATP binding site [chemical binding]; other site
933093005437	Q-loop/lid; other site
933093005438	ABC transporter signature motif; other site
933093005439	Walker B; other site
933093005440	D-loop; other site
933093005441	H-loop/switch region; other site
933093005442	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
933093005443	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones]; Region: ATM1; COG5265
933093005444	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
933093005445	Walker A/P-loop; other site
933093005446	ATP binding site [chemical binding]; other site
933093005447	Q-loop/lid; other site
933093005448	ABC transporter signature motif; other site
933093005449	Walker B; other site
933093005450	D-loop; other site
933093005451	H-loop/switch region; other site
933093005452	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
933093005453	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
933093005454	active site
933093005455	catalytic tetrad [active]
933093005456	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
933093005457	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
933093005458	Uncharacterized subfamily of N-terminal LabA-like domains; Region: LabA_like_N_1; cd11297
933093005459	putative metal binding site [ion binding]; other site
933093005460	Uncharacterized conserved protein [Function unknown]; Region: COG1432
933093005461	C-terminal domain of LabA_like proteins; Region: LabA_like_C; cd10146
933093005462	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
933093005463	homodimer interface [polypeptide binding]; other site
933093005464	active site
933093005465	putative chemical substrate binding site [chemical binding]; other site
933093005466	metal binding site [ion binding]; metal-binding site
933093005467	Transposase Tn5 dimerisation domain; Region: Dimer_Tnp_Tn5; pfam02281
933093005468	N-terminal domain of reverse transcriptase; Region: RVT_N; pfam13655
933093005469	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
933093005470	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
933093005471	putative active site [active]
933093005472	putative NTP binding site [chemical binding]; other site
933093005473	putative nucleic acid binding site [nucleotide binding]; other site
933093005474	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
933093005475	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
933093005476	conjugative transfer relaxase protein TraI; Region: TraI_TIGR; TIGR02760
933093005477	conjugative relaxase domain, TrwC/TraI family; Region: relax_trwC; TIGR02686
933093005478	AAA domain; Region: AAA_30; pfam13604
933093005479	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
933093005480	active site
933093005481	metal binding site [ion binding]; metal-binding site
933093005482	interdomain interaction site; other site
933093005483	type IV conjugative transfer system coupling protein TraD; Region: TraD_Ftype; TIGR02759
933093005484	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
933093005485	Walker A motif; other site
933093005486	ATP binding site [chemical binding]; other site
933093005487	Walker B motif; other site
933093005488	TraG-like protein, N-terminal region; Region: TraG_N; pfam07916
933093005489	Conjugative relaxosome accessory transposon protein; Region: TraH; pfam06122
933093005490	type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB; Region: TrbB; TIGR02738
933093005491	type-F conjugative transfer system pilin assembly protein TraF; Region: TraF; TIGR02739
933093005492	F plasmid transfer operon protein; Region: TraF; pfam13728
933093005493	type-F conjugative transfer system mating-pair stabilization protein TraN; Region: TraN_Ftype; TIGR02750
933093005494	type-F conjugative transfer system pilin assembly protein TrbC; Region: TrbC_Ftype; TIGR02742
933093005495	TraU protein; Region: TraU; cl06067
933093005496	type-F conjugative transfer system protein TraW; Region: TraW; TIGR02743
933093005497	F pilus assembly Type-IV secretion system for plasmid transfer; Region: TraC_F_IV; pfam11130
933093005498	type-IV secretion system protein TraC; Region: TraC-F-type; TIGR02746
933093005499	type IV conjugative transfer system lipoprotein TraV; Region: TraV; TIGR02747
933093005500	Type IV conjugative transfer system lipoprotein (TraV); Region: TraV; pfam09676
933093005501	Bacterial conjugation TrbI-like protein; Region: TrbI; pfam03743
933093005502	TraK protein; Region: TraK; pfam06586
933093005503	type-F conjugative transfer system secretin TraK; Region: TraK_Ftype; TIGR02756
933093005504	type IV conjugative transfer system protein TraE; Region: TraE_TIGR; TIGR02761
933093005505	type IV conjugative transfer system protein TraL; Region: TraL_TIGR; TIGR02762
933093005506	Global regulator protein family; Region: CsrA; pfam02599
933093005507	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
933093005508	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
933093005509	non-specific DNA binding site [nucleotide binding]; other site
933093005510	salt bridge; other site
933093005511	sequence-specific DNA binding site [nucleotide binding]; other site
933093005512	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
933093005513	Catalytic site [active]
933093005514	DDE superfamily endonuclease; Region: DDE_5; cl17874
933093005515	Peptide methionine sulfoxide reductase; Region: PMSR; pfam01625
933093005516	methionine sulfoxide reductase B; Provisional; Region: PRK00222
933093005517	SelR domain; Region: SelR; pfam01641
933093005518	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
933093005519	Uncharacterized conserved protein [Function unknown]; Region: COG0398
933093005520	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
933093005521	mercuric reductase; Validated; Region: PRK06370
933093005522	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
933093005523	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
933093005524	Sterol desaturase [Lipid metabolism]; Region: ERG3; COG3000
933093005525	Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; pfam04116
933093005526	Phage integrase, N-terminal SAM-like domain; Region: Phage_integr_N; cl12235
933093005527	MAPEG family; Region: MAPEG; cl09190
933093005528	Predicted membrane protein [Function unknown]; Region: COG2259
933093005529	Uncharacterized protein conserved in bacteria (DUF2063); Region: DUF2063; pfam09836
933093005530	hypothetical protein; Provisional; Region: PRK05409
933093005531	Predicted integral membrane protein (DUF2282); Region: DUF2282; pfam10048
933093005532	Ribosomal protein L24e/L24 is a ribosomal protein found in eukaryotes (L24) and in archaea (L24e, distinct from archaeal L24). L24e/L24 is located on the surface of the large subunit, adjacent to proteins L14 and L3, and near the translation factor...; Region: Ribosomal_L24e_L24; cl00909
933093005533	methionine sulfoxide reductase B; Provisional; Region: PRK00222
933093005534	SelR domain; Region: SelR; pfam01641
933093005535	uncharacterized peroxidase-related enzyme; Region: peroxid_rel; TIGR01926
933093005536	alkylhydroperoxidase AhpD family core domain; Region: ahpD_dom; TIGR00778
933093005537	Abi-like protein; Region: Abi_2; pfam07751
933093005538	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
933093005539	active site
933093005540	DNA binding site [nucleotide binding]
933093005541	Int/Topo IB signature motif; other site
933093005542	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
933093005543	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
933093005544	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
933093005545	Coenzyme A binding pocket [chemical binding]; other site
933093005546	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093005547	metabolite-proton symporter; Region: 2A0106; TIGR00883
933093005548	putative substrate translocation pore; other site
933093005549	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
933093005550	Coenzyme A binding pocket [chemical binding]; other site
933093005551	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
933093005552	Serine hydrolase; Region: Ser_hydrolase; cl17834
933093005553	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
933093005554	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
933093005555	DNA binding residues [nucleotide binding]
933093005556	dimerization interface [polypeptide binding]; other site
933093005557	Domain of unknown function DUF302; Region: DUF302; cl01364
933093005558	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
933093005559	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
933093005560	Soluble P-type ATPase [General function prediction only]; Region: COG4087
933093005561	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
933093005562	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
933093005563	metal-binding site [ion binding]
933093005564	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
933093005565	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
933093005566	heavy metal efflux pump, CzcA family; Region: 2A0601; TIGR00914
933093005567	Membrane-fusion protein [Cell envelope biogenesis, outer membrane]; Region: AcrA; COG0845
933093005568	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
933093005569	E3 interaction surface; other site
933093005570	lipoyl attachment site [posttranslational modification]; other site
933093005571	HlyD family secretion protein; Region: HlyD_3; pfam13437
933093005572	Outer membrane efflux protein; Region: OEP; pfam02321
933093005573	Outer membrane efflux protein; Region: OEP; pfam02321
933093005574	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
933093005575	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
933093005576	non-specific DNA binding site [nucleotide binding]; other site
933093005577	salt bridge; other site
933093005578	sequence-specific DNA binding site [nucleotide binding]; other site
933093005579	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
933093005580	Catalytic site [active]
933093005581	Global regulator protein family; Region: CsrA; pfam02599
933093005582	conjugative transfer region protein, TIGR03748 family; Region: conj_PilL
933093005583	integrating conjugative element protein, PFL_4693 family; Region: conj_TIGR03759
933093005584	Protein of unknown function (DUF2859); Region: DUF2859; pfam11072
933093005585	Domain of unknown function (DUF4400); Region: DUF4400; cl14023
933093005586	Plasmid protein of unknown function (Plasmid_RAQPRD); Region: Plasmid_RAQPRD; pfam09686
933093005587	conjugative transfer region protein, TIGR03750 family; Region: conj_TIGR03750
933093005588	Protein of unknown function (DUF2895); Region: DUF2895; pfam11444
933093005589	Protein of unknown function (DUF3438); Region: DUF3438; cl13372
933093005590	integrating conjugative element protein, PFL_4705 family; Region: conj_TIGR03752
933093005591	basic region leucin zipper; Region: BRLZ; smart00338
933093005592	conjugative transfer region lipoprotein, TIGR03751 family; Region: conj_TIGR03751
933093005593	conjugative transfer ATPase, PFL_4706 family; Region: traC_PFL_4706; TIGR03744
933093005594	F pilus assembly Type-IV secretion system for plasmid transfer; Region: TraC_F_IV; pfam11130
933093005595	Domain of unknown function DUF87; Region: DUF87; pfam01935
933093005596	integrating conjugative element protein, PFL_4710 family; Region: conj_TIGR03756
933093005597	integrating conjugative element protein, PFL_4711 family; Region: conj_TIGR03755
933093005598	TraG-like protein, N-terminal region; Region: TraG_N; pfam07916
933093005599	conjugative coupling factor TraD, SXT/TOL subfamily; Region: SXT_TraD; TIGR03743
933093005600	conjugative coupling factor TraD, TOL family; Region: conj_TOL_TraD; TIGR03754
933093005601	Protein of unknown function (DUF3644); Region: DUF3644; pfam12358
933093005602	Phage integrase, N-terminal; Region: Integrase_l_N; pfam12834
933093005603	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
933093005604	active site
933093005605	catalytic residues [active]
933093005606	DNA binding site [nucleotide binding]
933093005607	Int/Topo IB signature motif; other site
933093005608	Antirestriction protein (ArdA); Region: ArdA; pfam07275
933093005609	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
933093005610	Transposase Tn5 dimerisation domain; Region: Dimer_Tnp_Tn5; pfam02281
933093005611	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
933093005612	Transposase; Region: DDE_Tnp_ISL3; pfam01610
933093005613	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
933093005614	Transposase; Region: DDE_Tnp_ISL3; pfam01610
933093005615	Helix-turn-helix domain; Region: HTH_28; pfam13518
933093005616	Winged helix-turn helix; Region: HTH_29; pfam13551
933093005617	Homeodomain-like domain; Region: HTH_32; pfam13565
933093005618	Integrase core domain; Region: rve; pfam00665
933093005619	Integrase core domain; Region: rve_3; pfam13683
933093005620	Transposase Tn5 dimerisation domain; Region: Dimer_Tnp_Tn5; pfam02281
933093005621	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
933093005622	DNA-binding site [nucleotide binding]; DNA binding site
933093005623	RNA-binding motif; other site
933093005624	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
933093005625	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
933093005626	ATP binding site [chemical binding]; other site
933093005627	Mg++ binding site [ion binding]; other site
933093005628	motif III; other site
933093005629	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
933093005630	nucleotide binding region [chemical binding]; other site
933093005631	ATP-binding site [chemical binding]; other site
933093005632	RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501
933093005633	putative RNA binding site [nucleotide binding]; other site
933093005634	Cation efflux family; Region: Cation_efflux; cl00316
933093005635	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
933093005636	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
933093005637	ligand binding site [chemical binding]; other site
933093005638	K+ potassium transporter; Region: K_trans; pfam02705
933093005639	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
933093005640	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
933093005641	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
933093005642	PAS domain S-box; Region: sensory_box; TIGR00229
933093005643	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
933093005644	putative active site [active]
933093005645	heme pocket [chemical binding]; other site
933093005646	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
933093005647	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
933093005648	metal binding site [ion binding]; metal-binding site
933093005649	active site
933093005650	I-site; other site
933093005651	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093005652	metabolite-proton symporter; Region: 2A0106; TIGR00883
933093005653	putative substrate translocation pore; other site
933093005654	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
933093005655	Protein export membrane protein; Region: SecD_SecF; cl14618
933093005656	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
933093005657	carboxyltransferase (CT) interaction site; other site
933093005658	biotinylation site [posttranslational modification]; other site
933093005659	HlyD family secretion protein; Region: HlyD_3; pfam13437
933093005660	Outer membrane efflux protein; Region: OEP; pfam02321
933093005661	Outer membrane efflux protein; Region: OEP; pfam02321
933093005662	Serine/threonine protein kinase [General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair]; Region: SPS1; COG0515
933093005663	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
933093005664	active site
933093005665	ATP binding site [chemical binding]; other site
933093005666	substrate binding site [chemical binding]; other site
933093005667	activation loop (A-loop); other site
933093005668	Transcriptional regulator [Transcription]; Region: LysR; COG0583
933093005669	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
933093005670	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
933093005671	dimerization interface [polypeptide binding]; other site
933093005672	pyridoxamine-phosphate oxidase; Region: pdxH; TIGR00558
933093005673	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
933093005674	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
933093005675	Predicted transcriptional regulators [Transcription]; Region: COG1733
933093005676	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
933093005677	classical (c) SDRs; Region: SDR_c; cd05233
933093005678	NAD(P) binding site [chemical binding]; other site
933093005679	active site
933093005680	F-box-like; Region: F-box-like; pfam12937
933093005681	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
933093005682	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
933093005683	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
933093005684	active site
933093005685	phosphorylation site [posttranslational modification]
933093005686	intermolecular recognition site; other site
933093005687	dimerization interface [polypeptide binding]; other site
933093005688	PAS domain; Region: PAS; smart00091
933093005689	PAS fold; Region: PAS_4; pfam08448
933093005690	putative active site [active]
933093005691	heme pocket [chemical binding]; other site
933093005692	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
933093005693	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
933093005694	dimer interface [polypeptide binding]; other site
933093005695	phosphorylation site [posttranslational modification]
933093005696	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
933093005697	ATP binding site [chemical binding]; other site
933093005698	Mg2+ binding site [ion binding]; other site
933093005699	G-X-G motif; other site
933093005700	Response regulator receiver domain; Region: Response_reg; pfam00072
933093005701	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
933093005702	active site
933093005703	phosphorylation site [posttranslational modification]
933093005704	intermolecular recognition site; other site
933093005705	dimerization interface [polypeptide binding]; other site
933093005706	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
933093005707	dimer interface [polypeptide binding]; other site
933093005708	phosphorylation site [posttranslational modification]
933093005709	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
933093005710	ATP binding site [chemical binding]; other site
933093005711	Mg2+ binding site [ion binding]; other site
933093005712	G-X-G motif; other site
933093005713	Streptomycin adenylyltransferase; Region: Adenyl_transf; pfam04439
933093005714	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
933093005715	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
933093005716	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
933093005717	Walker A/P-loop; other site
933093005718	ATP binding site [chemical binding]; other site
933093005719	Q-loop/lid; other site
933093005720	ABC transporter signature motif; other site
933093005721	Walker B; other site
933093005722	D-loop; other site
933093005723	H-loop/switch region; other site
933093005724	Dot/Icm substrate protein; Region: SidE; pfam12252
933093005725	Dot/Icm substrate protein; Region: SidE; pfam12252
933093005726	Dot/Icm substrate protein; Region: SidE; pfam12252
933093005727	Dot/Icm substrate protein; Region: SidE; pfam12252
933093005728	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
933093005729	S-adenosylmethionine binding site [chemical binding]; other site
933093005730	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
933093005731	C-20 methyltransferase BchU; Region: C20_methyl_CrtF; TIGR02716
933093005732	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
933093005733	S-adenosylmethionine binding site [chemical binding]; other site
933093005734	Protein of unknown function (DUF3141); Region: DUF3141; pfam11339
933093005735	Helix-turn-helix domain; Region: HTH_18; pfam12833
933093005736	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
933093005737	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
933093005738	Predicted transcriptional regulator [Transcription]; Region: COG2378
933093005739	HTH domain; Region: HTH_11; pfam08279
933093005740	WYL domain; Region: WYL; pfam13280
933093005741	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
933093005742	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
933093005743	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_11; cd07261
933093005744	putative dimer interface [polypeptide binding]; other site
933093005745	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
933093005746	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
933093005747	Coenzyme A binding pocket [chemical binding]; other site
933093005748	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
933093005749	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
933093005750	Coenzyme A binding pocket [chemical binding]; other site
933093005751	S-adenosylhomocysteine hydrolase [Coenzyme metabolism]; Region: SAM1; COG0499
933093005752	S-adenosyl-L-homocysteine hydrolase, NAD binding domain; Region: AdoHcyase_NAD; smart00997
933093005753	NAD binding site [chemical binding]; other site
933093005754	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
933093005755	Transposase; Region: DDE_Tnp_ISL3; pfam01610
933093005756	Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG3618
933093005757	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
933093005758	active site
933093005759	Glutamate decarboxylase and related PLP-dependent proteins [Amino acid transport and metabolism]; Region: GadB; COG0076
933093005760	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
933093005761	catalytic residue [active]
933093005762	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
933093005763	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
933093005764	HlyD family secretion protein; Region: HlyD_3; pfam13437
933093005765	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
933093005766	N-terminal formyl transferase catalytic core domain of NRPS_like proteins, one of the proteins involved in the synthesis of Oxazolomycin; Region: FMT_core_NRPS_like; cd08649
933093005767	putative active site [active]
933093005768	putative substrate binding site [chemical binding]; other site
933093005769	putative cosubstrate binding site; other site
933093005770	catalytic site [active]
933093005771	C-terminal subdomain of the Formyltransferase-like domain found in OzmH-like proteins; Region: FMT_C_OzmH_like; cd08700
933093005772	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
933093005773	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
933093005774	acyl-activating enzyme (AAE) consensus motif; other site
933093005775	AMP binding site [chemical binding]; other site
933093005776	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
933093005777	Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319
933093005778	PAS domain; Region: PAS; smart00091
933093005779	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
933093005780	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain); Region: PAC; smart00086
933093005781	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
933093005782	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
933093005783	dimer interface [polypeptide binding]; other site
933093005784	phosphorylation site [posttranslational modification]
933093005785	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
933093005786	ATP binding site [chemical binding]; other site
933093005787	Mg2+ binding site [ion binding]; other site
933093005788	G-X-G motif; other site
933093005789	Response regulator receiver domain; Region: Response_reg; pfam00072
933093005790	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
933093005791	active site
933093005792	phosphorylation site [posttranslational modification]
933093005793	intermolecular recognition site; other site
933093005794	dimerization interface [polypeptide binding]; other site
933093005795	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
933093005796	putative binding surface; other site
933093005797	active site
933093005798	PAS fold; Region: PAS_4; pfam08448
933093005799	Response regulator receiver domain; Region: Response_reg; pfam00072
933093005800	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
933093005801	active site
933093005802	phosphorylation site [posttranslational modification]
933093005803	intermolecular recognition site; other site
933093005804	dimerization interface [polypeptide binding]; other site
933093005805	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
933093005806	Methyltransferase domain; Region: Methyltransf_31; pfam13847
933093005807	S-adenosylmethionine binding site [chemical binding]; other site
933093005808	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
933093005809	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cl00184
933093005810	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
933093005811	Beta-ketoacyl synthase; Region: PKS_KS; smart00825
933093005812	active site
933093005813	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
933093005814	Beta-ketoacyl synthase; Region: PKS_KS; smart00825
933093005815	active site
933093005816	ketoreductase (KR) and fatty acid synthase (FAS), complex (x) SDRs; Region: KR_FAS_SDR_x; cd05274
933093005817	KR domain; Region: KR; pfam08659
933093005818	NADP binding site [chemical binding]; other site
933093005819	active site
933093005820	Phosphopantetheine attachment site; Region: PKS_PP; smart00823
933093005821	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
933093005822	Beta-ketoacyl synthase; Region: PKS_KS; smart00825
933093005823	active site
933093005824	Dehydratase domain in polyketide synthase (PKS) enzymes; Region: PKS_DH; smart00826
933093005825	beta-ketoacyl reductase (KR) domain of fatty acid synthase (FAS), subgroup 2, complex (x); Region: KR_2_FAS_SDR_x; cd08955
933093005826	KR domain; Region: KR; pfam08659
933093005827	putative NADP binding site [chemical binding]; other site
933093005828	active site
933093005829	Phosphopantetheine attachment site; Region: PKS_PP; smart00823
933093005830	Condensation domain; Region: Condensation; pfam00668
933093005831	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
933093005832	Macrophage killing protein with similarity to conjugation protein; Region: IcmL; pfam11393
933093005833	Macrophage killing protein with similarity to conjugation protein; Region: IcmL; pfam11393
933093005834	Macrophage killing protein with similarity to conjugation protein; Region: IcmL; pfam11393
933093005835	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
933093005836	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
933093005837	putative dimer interface [polypeptide binding]; other site
933093005838	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
933093005839	Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain  (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464
933093005840	putative dimer interface [polypeptide binding]; other site
933093005841	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
933093005842	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
933093005843	Sulfate transporter family; Region: Sulfate_transp; pfam00916
933093005844	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeC; cd03378
933093005845	active site clefts [active]
933093005846	zinc binding site [ion binding]; other site
933093005847	dimer interface [polypeptide binding]; other site
933093005848	Predicted ornithine cyclodeaminase, mu-crystallin homolog [Amino acid transport and metabolism]; Region: COG2423
933093005849	ornithine cyclodeaminase; Validated; Region: PRK06823; cl17400
933093005850	Ketosteroid isomerase homolog [Function unknown]; Region: COG4319
933093005851	SnoaL-like domain; Region: SnoaL_3; pfam13474
933093005852	amino acid/peptide transporter (Peptide:H+ symporter), bacterial; Region: yjdL_sub1_fam; TIGR00924
933093005853	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093005854	putative substrate translocation pore; other site
933093005855	POT family; Region: PTR2; cl17359
933093005856	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
933093005857	hypothetical protein; Reviewed; Region: PRK09588
933093005858	Archease protein family (MTH1598/TM1083); Region: Archease; pfam01951
933093005859	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
933093005860	L,D-transpeptidase catalytic domain; Region: YkuD_2; pfam13645
933093005861	Arginate lyase and other MDR family members; Region: AL_MDR; cd08252
933093005862	zinc-binding alcohol dehydrogenase family protein; Region: adh_fam_1; TIGR02817
933093005863	putative NAD(P) binding site [chemical binding]; other site
933093005864	dimer interface [polypeptide binding]; other site
933093005865	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
933093005866	substrate binding site [chemical binding]; other site
933093005867	Domain of unknown function (DUF4424); Region: DUF4424; pfam14415
933093005868	YARHG domain; Region: YARHG; pfam13308
933093005869	Uncharacterized protein family UPF0047; Region: UPF0047; pfam01894
933093005870	Arginase-like and histone-like hydrolases; Region: Arginase_HDAC; cl17011
933093005871	active site
933093005872	metal binding site [ion binding]; metal-binding site
933093005873	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
933093005874	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
933093005875	NAD(P) binding site [chemical binding]; other site
933093005876	active site
933093005877	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
933093005878	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
933093005879	PF-ChiA is an uncharacterized chitinase found in the hyperthermophilic archaeon Pyrococcus furiosus with a glycosyl hydrolase family 18 (GH18) catalytic domain as well as a cellulose-binding domain.  Members of this domain family are found not only in...; Region: GH18_PF-ChiA-like; cd06543
933093005880	active site
933093005881	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
933093005882	Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469
933093005883	[2Fe-2S] cluster binding site [ion binding]; other site
933093005884	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
933093005885	hydrophobic ligand binding site; other site
933093005886	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
933093005887	putative trimer interface [polypeptide binding]; other site
933093005888	putative CoA binding site [chemical binding]; other site
933093005889	Sel1 repeat; Region: Sel1; pfam08238
933093005890	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
933093005891	Sel1-like repeats; Region: SEL1; smart00671
933093005892	Sel1 repeat; Region: Sel1; pfam08238
933093005893	Sel1-like repeats; Region: SEL1; smart00671
933093005894	Sel1-like repeats; Region: SEL1; smart00671
933093005895	Sel1-like repeats; Region: SEL1; smart00671
933093005896	Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell division and chromosome partitioning / Cytoskeleton]; Region: ATS1; COG5184
933093005897	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
933093005898	GH3 auxin-responsive promoter; Region: GH3; pfam03321
933093005899	cyclohexanecarboxyl-CoA dehydrogenase; Region: cyc_hxne_CoA_dh; TIGR03207
933093005900	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
933093005901	active site
933093005902	methylmalonyl-CoA decarboxylase alpha subunit; Region: mmdA; TIGR01117
933093005903	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
933093005904	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
933093005905	3-oxoacyl-[acyl-carrier-protein]; Region: FabH; COG0332
933093005906	Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the...; Region: cond_enzymes; cl09938
933093005907	active site
933093005908	acyl-CoA synthetase; Validated; Region: PRK05850
933093005909	Fatty acyl-AMP ligase (FAAL); Region: FAAL; cd05931
933093005910	acyl-activating enzyme (AAE) consensus motif; other site
933093005911	active site
933093005912	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
933093005913	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
933093005914	acyl-activating enzyme (AAE) consensus motif; other site
933093005915	AMP binding site [chemical binding]; other site
933093005916	active site
933093005917	CoA binding site [chemical binding]; other site
933093005918	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
933093005919	classical (c) SDRs; Region: SDR_c; cd05233
933093005920	NAD(P) binding site [chemical binding]; other site
933093005921	active site
933093005922	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
933093005923	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
933093005924	dimer interface [polypeptide binding]; other site
933093005925	active site
933093005926	CoA binding pocket [chemical binding]; other site
933093005927	Phosphopantetheine attachment site; Region: PP-binding; cl09936
933093005928	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
933093005929	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093005930	putative substrate translocation pore; other site
933093005931	Sterol desaturase [Lipid metabolism]; Region: ERG3; COG3000
933093005932	Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; pfam04116
933093005933	Nitric oxide reductase large subunit [Inorganic ion transport and metabolism]; Region: NorB; COG3256
933093005934	Heme-copper oxidase subunit I.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which catalyze the reduction of O2 and simultaneously pump protons across the membrane.  The superfamily is...; Region: Heme_Cu_Oxidase_I; cl00275
933093005935	Binuclear center (active site) [active]
933093005936	K-pathway; other site
933093005937	Putative proton exit pathway; other site
933093005938	Putative water exit pathway; other site
933093005939	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
933093005940	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
933093005941	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
933093005942	Walker A/P-loop; other site
933093005943	ATP binding site [chemical binding]; other site
933093005944	Q-loop/lid; other site
933093005945	ABC transporter signature motif; other site
933093005946	Walker B; other site
933093005947	D-loop; other site
933093005948	H-loop/switch region; other site
933093005949	MAPEG family; Region: MAPEG; cl09190
933093005950	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
933093005951	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
933093005952	hypothetical protein; Validated; Region: PRK07198
933093005953	GTP cyclohydrolase N terminal; Region: GTP_CH_N; pfam12471
933093005954	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
933093005955	dimerization interface [polypeptide binding]; other site
933093005956	active site
933093005957	Protein of unknown function (DUF1688); Region: DUF1688; pfam07958
933093005958	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
933093005959	active site
933093005960	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
933093005961	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
933093005962	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
933093005963	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
933093005964	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
933093005965	GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518
933093005966	catalytic triad [active]
933093005967	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
933093005968	Iron-containing alcohol dehydrogenases-like, involved in the linear alkylbenzenesulfonate (LAS) degradation pathway; Region: Fe-ADH7; cd08192
933093005969	putative active site [active]
933093005970	metal binding site [ion binding]; metal-binding site
933093005971	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
933093005972	Uncharacterized aldehyde dehydrogenase of Synechococcus sp. PCC 7335 (EDX86601); Region: ALDH_EDX86601; cd07102
933093005973	NAD(P) binding site [chemical binding]; other site
933093005974	catalytic residues [active]
933093005975	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
933093005976	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
933093005977	Uncharacterized protein conserved in bacteria (DUF2063); Region: DUF2063; pfam09836
933093005978	hypothetical protein; Provisional; Region: PRK05409
933093005979	Predicted exonuclease of the beta-lactamase fold involved in RNA processing [Translation, ribosomal structure and biogenesis]; Region: YSH1; COG1236
933093005980	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
933093005981	Beta-Casp domain; Region: Beta-Casp; pfam10996
933093005982	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
933093005983	BON domain; Region: BON; pfam04972
933093005984	Poly-beta-hydroxybutyrate polymerase N terminal; Region: PHBC_N; pfam12551
933093005985	poly(R)-hydroxyalkanoic acid synthase, class I; Region: PHA_synth_I; TIGR01838
933093005986	Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus; Region: PhaC_N; pfam07167
933093005987	bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; Validated; Region: PRK08190
933093005988	(R)-hydratase [(R)-specific enoyl-CoA hydratase] catalyzes the hydration of trans-2-enoyl CoA to (R)-3-hydroxyacyl-CoA as part of the PHA (polyhydroxyalkanoate) biosynthetic pathway. (R)-hydratase contains a hot-dog fold similar to those of thioesterase...; Region: R_hydratase; cd03449
933093005989	dimer interaction site [polypeptide binding]; other site
933093005990	substrate-binding tunnel; other site
933093005991	active site
933093005992	catalytic site [active]
933093005993	substrate binding site [chemical binding]; other site
933093005994	phosphate acetyltransferase; Provisional; Region: PRK11890
933093005995	propionate/acetate kinase; Provisional; Region: PRK12379
933093005996	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
933093005997	nucleotide binding site [chemical binding]; other site
933093005998	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
933093005999	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
933093006000	HSP70 interaction site [polypeptide binding]; other site
933093006001	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
933093006002	substrate binding site [polypeptide binding]; other site
933093006003	dimer interface [polypeptide binding]; other site
933093006004	chaperone-modulator protein CbpM; Provisional; Region: PRK10265
933093006005	MerR HTH family regulatory protein; Region: MerR_2; pfam13591
933093006006	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
933093006007	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ABO13168; Region: LPLAT_ABO13168-like; cd07988
933093006008	putative acyl-acceptor binding pocket; other site
933093006009	Protein of unknown function (DUF1415); Region: DUF1415; pfam07209
933093006010	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
933093006011	Imidazolonepropionase and related amidohydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: HutI; COG1228
933093006012	Metallo-dependent hydrolases, subgroup A is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_A; cd01299
933093006013	active site
933093006014	probable DNA repair protein; Region: TIGR03623
933093006015	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
933093006016	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cl00641
933093006017	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
933093006018	putative NAD(P) binding site [chemical binding]; other site
933093006019	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
933093006020	Predicted small integral membrane protein (DUF2165); Region: DUF2165; pfam09933
933093006021	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
933093006022	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
933093006023	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
933093006024	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
933093006025	putative active site [active]
933093006026	catalytic site [active]
933093006027	putative metal binding site [ion binding]; other site
933093006028	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
933093006029	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Region: ELFV_dehydrog; pfam00208
933093006030	NAD(P) binding domain of leucine dehydrogenase, phenylalanine dehydrogenase, and valine dehydrogenase; Region: NAD_bind_Leu_Phe_Val_DH; cd01075
933093006031	NAD binding site [chemical binding]; other site
933093006032	Phe binding site; other site
933093006033	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
933093006034	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
933093006035	S-adenosylmethionine binding site [chemical binding]; other site
933093006036	4-hydroxyphenylpyruvate dioxygenase; Region: 4HPPD; TIGR01263
933093006037	N-terminal domain of 4-hydroxyphenylpyruvate dioxygenase (HPPD) and hydroxymandelate Synthase (HmaS); Region: HPPD_N_like; cd08342
933093006038	dimer interface [polypeptide binding]; other site
933093006039	C-terminal domain of 4-hydroxyphenylpyruvate dioxygenase (HppD) and hydroxymandelate Synthase (HmaS); Region: HPPD_C_like; cd07250
933093006040	active site
933093006041	Fe binding site [ion binding]; other site
933093006042	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
933093006043	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
933093006044	GST_N family, Class Zeta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Zeta; cd03042
933093006045	maleylacetoacetate isomerase; Region: maiA; TIGR01262
933093006046	C-terminal domain interface [polypeptide binding]; other site
933093006047	GSH binding site (G-site) [chemical binding]; other site
933093006048	putative dimer interface [polypeptide binding]; other site
933093006049	C-terminal, alpha helical domain of Class Zeta Glutathione S-transferases; Region: GST_C_Zeta; cd03191
933093006050	dimer interface [polypeptide binding]; other site
933093006051	N-terminal domain interface [polypeptide binding]; other site
933093006052	maleylacetoacetate (MAA) substrate binding site (H site) [chemical binding]; other site
933093006053	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
933093006054	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
933093006055	putative dimer interface [polypeptide binding]; other site
933093006056	putative anticodon binding site; other site
933093006057	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
933093006058	homodimer interface [polypeptide binding]; other site
933093006059	motif 1; other site
933093006060	motif 2; other site
933093006061	active site
933093006062	motif 3; other site
933093006063	lipoprotein releasing system, ATP-binding protein; Region: LolD_lipo_ex; TIGR02211
933093006064	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
933093006065	Walker A/P-loop; other site
933093006066	ATP binding site [chemical binding]; other site
933093006067	Q-loop/lid; other site
933093006068	ABC transporter signature motif; other site
933093006069	Walker B; other site
933093006070	D-loop; other site
933093006071	H-loop/switch region; other site
933093006072	lipoprotein releasing system, transmembrane protein, LolC/E family; Region: lolCE; TIGR02212
933093006073	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
933093006074	FtsX-like permease family; Region: FtsX; pfam02687
933093006075	Pirin-related protein [General function prediction only]; Region: COG1741
933093006076	Pirin; Region: Pirin; pfam02678
933093006077	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
933093006078	Acyl carrier protein phosphodiesterase [Lipid metabolism]; Region: AcpD; COG1182
933093006079	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
933093006080	LysR family transcriptional regulator; Provisional; Region: PRK14997
933093006081	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
933093006082	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
933093006083	dimerization interface [polypeptide binding]; other site
933093006084	potential protein location (hypothetical protein lp12_2281 [Legionella pneumophila subsp. pneumophila ATCC 43290]) that overlaps RNA (tRNA-L)
933093006085	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
933093006086	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
933093006087	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
933093006088	motif II; other site
933093006089	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
933093006090	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
933093006091	RNA binding surface [nucleotide binding]; other site
933093006092	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
933093006093	active site
933093006094	Ribonucleases G and E [Translation, ribosomal structure and biogenesis]; Region: CafA; COG1530
933093006095	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
933093006096	homodimer interface [polypeptide binding]; other site
933093006097	oligonucleotide binding site [chemical binding]; other site
933093006098	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
933093006099	ATP-dependent helicase HepA; Validated; Region: PRK04914
933093006100	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
933093006101	ATP binding site [chemical binding]; other site
933093006102	putative Mg++ binding site [ion binding]; other site
933093006103	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
933093006104	nucleotide binding region [chemical binding]; other site
933093006105	ATP-binding site [chemical binding]; other site
933093006106	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
933093006107	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
933093006108	Smr domain; Region: Smr; pfam01713
933093006109	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
933093006110	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
933093006111	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
933093006112	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
933093006113	Tetramer interface [polypeptide binding]; other site
933093006114	active site
933093006115	FMN-binding site [chemical binding]; other site
933093006116	HemK family putative methylases; Region: hemK_fam; TIGR00536
933093006117	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
933093006118	S-adenosylmethionine binding site [chemical binding]; other site
933093006119	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
933093006120	Smr domain; Region: Smr; pfam01713
933093006121	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
933093006122	active site residue [active]
933093006123	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
933093006124	GSH binding site [chemical binding]; other site
933093006125	catalytic residues [active]
933093006126	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
933093006127	SecA binding site; other site
933093006128	Preprotein binding site; other site
933093006129	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
933093006130	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
933093006131	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
933093006132	glutamate racemase; Provisional; Region: PRK00865
933093006133	Domain of unknown function (DUF1704); Region: DUF1704; pfam08014
933093006134	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
933093006135	dihydrodipicolinate synthase; Region: dapA; TIGR00674
933093006136	dimer interface [polypeptide binding]; other site
933093006137	active site
933093006138	catalytic residue [active]
933093006139	3-hydroxybutyrate dehydrogenase; Provisional; Region: PRK12429
933093006140	classical (c) SDRs; Region: SDR_c; cd05233
933093006141	NAD(P) binding site [chemical binding]; other site
933093006142	active site
933093006143	Hypothetical patatin similar to Z1214 protein of Escherichia coli; Region: Pat_hypo_Ecoli_Z1214_like; cd07209
933093006144	nucleophile elbow; other site
933093006145	Patatin phospholipase; Region: DUF3734; pfam12536
933093006146	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
933093006147	flagellar motor protein MotA; Validated; Region: PRK09110
933093006148	Flagellar motor protein [Cell motility and secretion]; Region: MotB; COG1360
933093006149	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
933093006150	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
933093006151	ligand binding site [chemical binding]; other site
933093006152	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
933093006153	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
933093006154	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
933093006155	Ankyrin repeats (many copies); Region: Ank_5; pfam13857
933093006156	Tfp pilus assembly protein, ATPase PilU [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilU; COG5008
933093006157	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
933093006158	ATP binding site [chemical binding]; other site
933093006159	Walker B motif; other site
933093006160	sugar 1,4-lactone oxidases; Region: FAD_lactone_ox; TIGR01678
933093006161	Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; pfam05721
933093006162	DNA repair protein RadA; Provisional; Region: PRK11823
933093006163	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
933093006164	Walker A motif; other site
933093006165	ATP binding site [chemical binding]; other site
933093006166	Walker B motif; other site
933093006167	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
933093006168	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
933093006169	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
933093006170	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
933093006171	substrate binding pocket [chemical binding]; other site
933093006172	chain length determination region; other site
933093006173	substrate-Mg2+ binding site; other site
933093006174	catalytic residues [active]
933093006175	aspartate-rich region 1; other site
933093006176	active site lid residues [active]
933093006177	aspartate-rich region 2; other site
933093006178	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
933093006179	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
933093006180	S-adenosylmethionine binding site [chemical binding]; other site
933093006181	comF family protein; Region: comF; TIGR00201
933093006182	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
933093006183	active site
933093006184	Predicted membrane-associated Zn-dependent proteases 1 [Cell envelope biogenesis, outer membrane]; Region: COG0750
933093006185	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
933093006186	active site
933093006187	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
933093006188	protein binding site [polypeptide binding]; other site
933093006189	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
933093006190	putative substrate binding region [chemical binding]; other site
933093006191	GrpE; Region: GrpE; pfam01025
933093006192	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
933093006193	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
933093006194	tRNA; other site
933093006195	putative tRNA binding site [nucleotide binding]; other site
933093006196	putative NADP binding site [chemical binding]; other site
933093006197	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
933093006198	peptide chain release factor 1; Validated; Region: prfA; PRK00591
933093006199	This domain is found in peptide chain release factors; Region: PCRF; smart00937
933093006200	RF-1 domain; Region: RF-1; pfam00472
933093006201	protein-(glutamine-N5) methyltransferase, release factor-specific; Region: RF_mod_PrmC; TIGR03534
933093006202	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
933093006203	S-adenosylmethionine binding site [chemical binding]; other site
933093006204	Prokaryotic dksA/traR C4-type zinc finger; Region: zf-dskA_traR; cl00755
933093006205	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
933093006206	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
933093006207	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
933093006208	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
933093006209	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
933093006210	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
933093006211	putative metal binding site [ion binding]; other site
933093006212	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
933093006213	HSP70 interaction site [polypeptide binding]; other site
933093006214	Protein of unknown function (DUF3530); Region: DUF3530; pfam12048
933093006215	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
933093006216	Fatty acyltransferase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: fatty_acyltransferase_like; cd01846
933093006217	active site
933093006218	catalytic triad [active]
933093006219	oxyanion hole [active]
933093006220	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
933093006221	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
933093006222	ATP binding site [chemical binding]; other site
933093006223	Mg++ binding site [ion binding]; other site
933093006224	motif III; other site
933093006225	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
933093006226	nucleotide binding region [chemical binding]; other site
933093006227	ATP-binding site [chemical binding]; other site
933093006228	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
933093006229	putative RNA binding site [nucleotide binding]; other site
933093006230	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
933093006231	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
933093006232	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
933093006233	2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli  is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930
933093006234	active site
933093006235	FMN binding site [chemical binding]; other site
933093006236	2,4-decadienoyl-CoA binding site; other site
933093006237	catalytic residue [active]
933093006238	4Fe-4S cluster binding site [ion binding]; other site
933093006239	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
933093006240	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
933093006241	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
933093006242	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
933093006243	E-class dimer interface [polypeptide binding]; other site
933093006244	P-class dimer interface [polypeptide binding]; other site
933093006245	active site
933093006246	Cu2+ binding site [ion binding]; other site
933093006247	Zn2+ binding site [ion binding]; other site
933093006248	alkylhydroperoxidase, AhpD family; Region: ahpD; TIGR00777
933093006249	alkylhydroperoxidase AhpD family core domain; Region: ahpD_dom; TIGR00778
933093006250	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
933093006251	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
933093006252	dimer interface [polypeptide binding]; other site
933093006253	decamer (pentamer of dimers) interface [polypeptide binding]; other site
933093006254	catalytic triad [active]
933093006255	peroxidatic and resolving cysteines [active]
933093006256	malate dehydrogenase; Provisional; Region: PRK05442
933093006257	Chloroplast-like malate dehydrogenases; Region: MDH_choloroplast_like; cd01338
933093006258	NAD(P) binding site [chemical binding]; other site
933093006259	dimer interface [polypeptide binding]; other site
933093006260	malate binding site [chemical binding]; other site
933093006261	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
933093006262	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
933093006263	dimer interface [polypeptide binding]; other site
933093006264	ADP-ribose binding site [chemical binding]; other site
933093006265	active site
933093006266	nudix motif; other site
933093006267	metal binding site [ion binding]; metal-binding site
933093006268	HemN family oxidoreductase; Provisional; Region: PRK05660
933093006269	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
933093006270	FeS/SAM binding site; other site
933093006271	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
933093006272	Amidase; Region: Amidase; pfam01425
933093006273	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
933093006274	UGMP family protein; Validated; Region: PRK09604
933093006275	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
933093006276	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
933093006277	Yqey-like protein; Region: YqeY; pfam09424
933093006278	DNA primase; Validated; Region: dnaG; PRK05667
933093006279	CHC2 zinc finger; Region: zf-CHC2; pfam01807
933093006280	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
933093006281	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
933093006282	active site
933093006283	metal binding site [ion binding]; metal-binding site
933093006284	interdomain interaction site; other site
933093006285	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
933093006286	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; smart00766
933093006287	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
933093006288	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
933093006289	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
933093006290	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
933093006291	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
933093006292	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
933093006293	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
933093006294	DNA binding residues [nucleotide binding]
933093006295	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
933093006296	Transposase; Region: DDE_Tnp_ISL3; pfam01610
933093006297	breast cancer carboxy-terminal domain; Region: BRCT; smart00292
933093006298	Dimer interface [polypeptide binding]; other site
933093006299	Domain of unknown function (DUF927); Region: DUF927; pfam06048
933093006300	Helix-turn-helix domain; Region: HTH_17; pfam12728
933093006301	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
933093006302	non-specific DNA binding site [nucleotide binding]; other site
933093006303	salt bridge; other site
933093006304	sequence-specific DNA binding site [nucleotide binding]; other site
933093006305	HipA N-terminal domain; Region: couple_hipA; TIGR03071
933093006306	Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550
933093006307	HipA-like N-terminal domain; Region: HipA_N; pfam07805
933093006308	HipA-like C-terminal domain; Region: HipA_C; pfam07804
933093006309	Cupin domain; Region: Cupin_2; cl17218
933093006310	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cl00214
933093006311	Transcriptional regulator [Transcription]; Region: LysR; COG0583
933093006312	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
933093006313	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
933093006314	substrate binding pocket [chemical binding]; other site
933093006315	dimerization interface [polypeptide binding]; other site
933093006316	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
933093006317	non-specific DNA binding site [nucleotide binding]; other site
933093006318	salt bridge; other site
933093006319	sequence-specific DNA binding site [nucleotide binding]; other site
933093006320	HipA N-terminal domain; Region: Couple_hipA; cl11853
933093006321	HipA-like N-terminal domain; Region: HipA_N; pfam07805
933093006322	HipA-like C-terminal domain; Region: HipA_C; pfam07804
933093006323	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
933093006324	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
933093006325	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
933093006326	Soluble P-type ATPase [General function prediction only]; Region: COG4087
933093006327	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
933093006328	Transcriptional regulator [Transcription]; Region: LysR; COG0583
933093006329	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
933093006330	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
933093006331	putative effector binding pocket; other site
933093006332	dimerization interface [polypeptide binding]; other site
933093006333	potassium uptake protein; Region: kup; TIGR00794
933093006334	K+ potassium transporter; Region: K_trans; pfam02705
933093006335	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
933093006336	active site
933093006337	outer membrane protease; Reviewed; Region: PRK10993
933093006338	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
933093006339	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
933093006340	N-terminal catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_1; cd00649
933093006341	dimer interface [polypeptide binding]; other site
933093006342	active site
933093006343	heme binding site [chemical binding]; other site
933093006344	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
933093006345	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093006346	metabolite-proton symporter; Region: 2A0106; TIGR00883
933093006347	putative substrate translocation pore; other site
933093006348	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
933093006349	Substrate binding site [chemical binding]; other site
933093006350	Ferritin-like domain; Region: Ferritin; pfam00210
933093006351	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
933093006352	dinuclear metal binding motif [ion binding]; other site
933093006353	Methyltransferase domain; Region: Methyltransf_31; pfam13847
933093006354	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
933093006355	S-adenosylmethionine binding site [chemical binding]; other site
933093006356	Peptidase family M23; Region: Peptidase_M23; pfam01551
933093006357	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
933093006358	Acetyltransferase (GNAT) domain; Region: Acetyltransf_8; pfam13523
933093006359	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
933093006360	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
933093006361	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
933093006362	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
933093006363	Leucine-rich repeats; other site
933093006364	Substrate binding site [chemical binding]; other site
933093006365	Beta-lactamase; Region: Beta-lactamase; pfam00144
933093006366	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
933093006367	Transcriptional regulator [Transcription]; Region: LysR; COG0583
933093006368	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
933093006369	The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466
933093006370	putative substrate binding pocket [chemical binding]; other site
933093006371	putative dimerization interface [polypeptide binding]; other site
933093006372	trans-cinnamate 4-monooxygenase; Region: PLN02394
933093006373	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
933093006374	nudix motif; other site
933093006375	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
933093006376	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
933093006377	ExoU and VipD-like proteins; homologus to patatin, cPLA2, and iPLA2; Region: Pat_ExoU_VipD_like; cd07207
933093006378	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
933093006379	active site
933093006380	nucleophile elbow; other site
933093006381	beta-lactamase/D-alanine carboxypeptidase; Provisional; Region: ampC; PRK11289
933093006382	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
933093006383	Ras GTPase Activating Domain; Region: RasGAP; cl02569
933093006384	Small integral membrane protein [Function unknown]; Region: COG5487; cl17674
933093006385	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
933093006386	Beta-lactamase; Region: Beta-lactamase; pfam00144
933093006387	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
933093006388	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
933093006389	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
933093006390	Coenzyme A binding pocket [chemical binding]; other site
933093006391	malonate decarboxylase, alpha subunit; Region: mdcA; TIGR01110
933093006392	Coenzyme A transferase; Region: CoA_trans; cl17247
933093006393	malonate decarboxylase acyl carrier protein; Region: malonate_delta; TIGR03130
933093006394	malonate decarboxylase, beta subunit; Region: malonate_beta; TIGR03133
933093006395	malonate decarboxylase, gamma subunit; Region: malonate_gamma; TIGR03134
933093006396	Phosphoribosyl-dephospho-CoA transferase MdcG; Region: MdcG; pfam10620
933093006397	malonate decarboxylase holo-[acyl-carrier-protein] synthase; Region: malonate_mdcG; TIGR03135
933093006398	triphosphoribosyl-dephospho-CoA synthase MdcB; Region: malonate_mdcB; TIGR03132
933093006399	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
933093006400	malonate decarboxylase, epsilon subunit; Region: malonate_mdcH; TIGR03131
933093006401	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
933093006402	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
933093006403	active site
933093006404	metal binding site [ion binding]; metal-binding site
933093006405	Cupin domain; Region: Cupin_2; cl17218
933093006406	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093006407	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
933093006408	putative substrate translocation pore; other site
933093006409	Predicted flavoprotein [General function prediction only]; Region: COG0431
933093006410	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
933093006411	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
933093006412	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
933093006413	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
933093006414	putative dimer interface [polypeptide binding]; other site
933093006415	N-terminal domain interface [polypeptide binding]; other site
933093006416	putative substrate binding pocket (H-site) [chemical binding]; other site
933093006417	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
933093006418	dimer interface [polypeptide binding]; other site
933093006419	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
933093006420	dimer interface [polypeptide binding]; other site
933093006421	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
933093006422	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
933093006423	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
933093006424	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
933093006425	D-ala-D-ala dipeptidase; Region: Peptidase_M15; cl00813
933093006426	N-acetyltransferase; Region: Acetyltransf_2; cl00949
933093006427	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
933093006428	Ankyrin repeats (many copies); Region: Ank_5; pfam13857
933093006429	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
933093006430	Coenzyme A binding pocket [chemical binding]; other site
933093006431	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
933093006432	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
933093006433	active site
933093006434	phosphorylation site [posttranslational modification]
933093006435	intermolecular recognition site; other site
933093006436	dimerization interface [polypeptide binding]; other site
933093006437	PAS domain S-box; Region: sensory_box; TIGR00229
933093006438	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
933093006439	putative active site [active]
933093006440	heme pocket [chemical binding]; other site
933093006441	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
933093006442	dimer interface [polypeptide binding]; other site
933093006443	phosphorylation site [posttranslational modification]
933093006444	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
933093006445	ATP binding site [chemical binding]; other site
933093006446	Mg2+ binding site [ion binding]; other site
933093006447	G-X-G motif; other site
933093006448	Heme NO binding; Region: HNOB; pfam07700
933093006449	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
933093006450	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
933093006451	Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases [Posttranslational modification, protein turnover, chaperones]; Region: COG3555
933093006452	guanine nucleotide-exchange factor domain of Legionella SidM/DrrA; Region: SidM_DrrA_GEF; cd11689
933093006453	Rab1 interaction interface [polypeptide binding]; other site
933093006454	Hydrogenase specific C-terminal endopeptidases, also called Hydrogen Maturation Proteases (H2MP). These enzymes belong to the peptidase family M52. Maturation of [FeNi] hydrogenases includes formation of the nickel metallocenter, proteolytic processing...; Region: H2MP; cd00518
933093006455	nickel binding site [ion binding]; other site
933093006456	Coenzyme F420-reducing hydrogenase, alpha subunit [Energy production and conversion]; Region: FrhA; COG3259
933093006457	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
933093006458	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
933093006459	cytochrome-c3 hydrogenase subunit gamma; Provisional; Region: PRK08345
933093006460	Anaerobic sulfite reductase contains an FAD and NADPH binding module with structural similarity to ferredoxin reductase and sequence similarity to dihydroorotate dehydrogenases. Clostridium pasteurianum inducible dissimilatory type sulfite reductase is...; Region: sulfite_reductase_like; cd06221
933093006461	FAD binding pocket [chemical binding]; other site
933093006462	FAD binding motif [chemical binding]; other site
933093006463	phosphate binding motif [ion binding]; other site
933093006464	beta-alpha-beta structure motif; other site
933093006465	NAD binding pocket [chemical binding]; other site
933093006466	Iron coordination center [ion binding]; other site
933093006467	4Fe-4S dicluster domain; Region: Fer4_18; pfam13746
933093006468	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
933093006469	dimerization interface [polypeptide binding]; other site
933093006470	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
933093006471	ATP binding site [chemical binding]; other site
933093006472	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
933093006473	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
933093006474	HupF/HypC family; Region: HupF_HypC; pfam01455
933093006475	Acylphosphatase; Region: Acylphosphatase; pfam00708
933093006476	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
933093006477	HypF finger; Region: zf-HYPF; pfam07503
933093006478	HypF finger; Region: zf-HYPF; pfam07503
933093006479	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
933093006480	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
933093006481	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
933093006482	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
933093006483	High-affinity nickel-transport protein; Region: NicO; cl00964
933093006484	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
933093006485	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
933093006486	Ligand binding site; other site
933093006487	Putative Catalytic site; other site
933093006488	DXD motif; other site
933093006489	GtrA-like protein; Region: GtrA; pfam04138
933093006490	uncharacterized YdjC-like family proteins from bacteria; Region: YdjC_like_3; cd10807
933093006491	putative active site [active]
933093006492	YdjC motif; other site
933093006493	Mg binding site [ion binding]; other site
933093006494	putative homodimer interface [polypeptide binding]; other site
933093006495	O-acetylserine/cysteine export protein; Provisional; Region: PRK11453
933093006496	EamA-like transporter family; Region: EamA; pfam00892
933093006497	EamA-like transporter family; Region: EamA; pfam00892
933093006498	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
933093006499	Uncharacterized conserved protein [Function unknown]; Region: COG2128
933093006500	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
933093006501	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
933093006502	active site
933093006503	dimerization interface [polypeptide binding]; other site
933093006504	TPR repeat; Region: TPR_11; pfam13414
933093006505	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
933093006506	binding surface
933093006507	TPR motif; other site
933093006508	TPR repeat; Region: TPR_11; pfam13414
933093006509	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
933093006510	binding surface
933093006511	TPR repeat; Region: TPR_11; pfam13414
933093006512	TPR motif; other site
933093006513	TPR repeat; Region: TPR_11; pfam13414
933093006514	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
933093006515	binding surface
933093006516	TPR repeat; Region: TPR_11; pfam13414
933093006517	TPR motif; other site
933093006518	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
933093006519	binding surface
933093006520	TPR motif; other site
933093006521	Predicted methyltransferase (contains TPR repeat) [General function prediction only]; Region: COG4976
933093006522	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
933093006523	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
933093006524	S-adenosylmethionine binding site [chemical binding]; other site
933093006525	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
933093006526	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
933093006527	active site
933093006528	substrate binding site [chemical binding]; other site
933093006529	metal binding site [ion binding]; metal-binding site
933093006530	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
933093006531	trimer interface [polypeptide binding]; other site
933093006532	active site
933093006533	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
933093006534	Flavoprotein; Region: Flavoprotein; pfam02441
933093006535	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
933093006536	hypothetical protein; Reviewed; Region: PRK00024
933093006537	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
933093006538	MPN+ (JAMM) motif; other site
933093006539	Zinc-binding site [ion binding]; other site
933093006540	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
933093006541	2'-5' RNA ligase; Region: 2_5_ligase; TIGR02258
933093006542	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
933093006543	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
933093006544	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD2; cd08298
933093006545	putative NAD(P) binding site [chemical binding]; other site
933093006546	putative substrate binding site [chemical binding]; other site
933093006547	catalytic Zn binding site [ion binding]; other site
933093006548	structural Zn binding site [ion binding]; other site
933093006549	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
933093006550	Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain  (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464
933093006551	putative dimer interface [polypeptide binding]; other site
933093006552	Kynurenine formamidase [Amino acid transport and metabolism]; Region: COG1878
933093006553	Homospermidine synthase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG5310
933093006554	Saccharopine dehydrogenase; Region: Saccharop_dh; pfam03435
933093006555	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
933093006556	Thiamine pyrophosphokinase; Region: TPK; cd07995
933093006557	thiamine pyrophosphokinase; Region: thi_PPkinase; TIGR01378
933093006558	active site
933093006559	dimerization interface [polypeptide binding]; other site
933093006560	thiamine binding site [chemical binding]; other site
933093006561	PQ loop repeat; Region: PQ-loop; pfam04193
933093006562	Possible lysine decarboxylase; Region: Lysine_decarbox; cl00695
933093006563	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeC; cd03378
933093006564	active site clefts [active]
933093006565	zinc binding site [ion binding]; other site
933093006566	dimer interface [polypeptide binding]; other site
933093006567	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093006568	Major Facilitator Superfamily; Region: MFS_1; pfam07690
933093006569	putative substrate translocation pore; other site
933093006570	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
933093006571	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
933093006572	dimer interface [polypeptide binding]; other site
933093006573	phosphorylation site [posttranslational modification]
933093006574	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
933093006575	ATP binding site [chemical binding]; other site
933093006576	Mg2+ binding site [ion binding]; other site
933093006577	G-X-G motif; other site
933093006578	Dot/Icm substrate protein; Region: SidE; pfam12252
933093006579	Flagellar motor switch protein [Cell motility and secretion]; Region: FliG; COG1536
933093006580	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
933093006581	Protein export membrane protein; Region: SecD_SecF; cl14618
933093006582	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
933093006583	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
933093006584	HlyD family secretion protein; Region: HlyD_3; pfam13437
933093006585	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
933093006586	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3323
933093006587	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093006588	D-galactonate transporter; Region: 2A0114; TIGR00893
933093006589	putative substrate translocation pore; other site
933093006590	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
933093006591	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
933093006592	putative DNA binding site [nucleotide binding]; other site
933093006593	putative Zn2+ binding site [ion binding]; other site
933093006594	AsnC family; Region: AsnC_trans_reg; pfam01037
933093006595	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Low Specificity D-Threonine Aldolase; Region: PLPDE_III_LS_D-TA; cd06819
933093006596	Predicted amino acid aldolase or racemase [Amino acid transport and metabolism]; Region: COG3616
933093006597	dimer interface [polypeptide binding]; other site
933093006598	active site
933093006599	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
933093006600	substrate binding site [chemical binding]; other site
933093006601	catalytic residue [active]
933093006602	VIP2; A family of actin-ADP-ribosylating toxin. A member of the Bacillus-prodiced vegetative insecticidal proteins (VIPs) possesses high specificity against the major insect pest, corn rootworms, and belongs to a classs of binary toxins and regulators of...; Region: VIP2; cl00173
933093006603	active site
933093006604	conformational flexibility of ligand binding pocket; other site
933093006605	ADP-ribosylating toxin turn-turn motif; other site
933093006606	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315
933093006607	DNA binding residues [nucleotide binding]
933093006608	dimerization interface [polypeptide binding]; other site
933093006609	F-box-like; Region: F-box-like; pfam12937
933093006610	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
933093006611	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
933093006612	active site
933093006613	catalytic site [active]
933093006614	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
933093006615	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
933093006616	Prephenate dehydratase; Region: PDT; pfam00800
933093006617	aspartate aminotransferase; Provisional; Region: PRK05764
933093006618	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
933093006619	pyridoxal 5'-phosphate binding site [chemical binding]; other site
933093006620	homodimer interface [polypeptide binding]; other site
933093006621	catalytic residue [active]
933093006622	tellurite resistance protein TehB; Provisional; Region: PRK12335
933093006623	Domain of unknown function (DUF1971); Region: DUF1971; pfam09313
933093006624	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
933093006625	S-adenosylmethionine binding site [chemical binding]; other site
933093006626	Transcriptional regulator; Region: Rrf2; cl17282
933093006627	Rrf2 family protein; Region: rrf2_super; TIGR00738
933093006628	Truncated hemoglobins (trHbs) are a family of oxygen-binding heme proteins found in cyanobacteria, eubacteria, unicellular eukaryotes, and plants. The truncated hemoglobins have a characteristic two-over-two alpha helical folding pattern that is distinct...; Region: Trunc_globin; cd00454
933093006629	apolar tunnel; other site
933093006630	heme binding site [chemical binding]; other site
933093006631	dimerization interface [polypeptide binding]; other site
933093006632	CDP-6-deoxy-delta-3,4-glucoseen reductase; Validated; Region: PRK07609
933093006633	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
933093006634	catalytic loop [active]
933093006635	iron binding site [ion binding]; other site
933093006636	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an N-terminal Iron-Sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible...; Region: FNR_N-term_Iron_sulfur_binding; cd06194
933093006637	FAD binding pocket [chemical binding]; other site
933093006638	FAD binding motif [chemical binding]; other site
933093006639	phosphate binding motif [ion binding]; other site
933093006640	beta-alpha-beta structure motif; other site
933093006641	NAD binding pocket [chemical binding]; other site
933093006642	Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG2159
933093006643	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
933093006644	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
933093006645	MltA specific insert domain; Region: MltA; cl08398
933093006646	3D domain; Region: 3D; pfam06725
933093006647	tRNA-binding-domain-containing CsaA-like proteins. CsaA is a molecular chaperone with export related activities. CsaA has a putative tRNA binding activity. The functional unit of CsaA is a homodimer and this domain acts as a dimerization domain; Region: tRNA_bind_CsaA; cd02798
933093006648	dimer interface [polypeptide binding]; other site
933093006649	putative tRNA-binding site [nucleotide binding]; other site
933093006650	EamA-like transporter family; Region: EamA; pfam00892
933093006651	EamA-like transporter family; Region: EamA; pfam00892
933093006652	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
933093006653	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
933093006654	Predicted membrane protein (DUF2306); Region: DUF2306; pfam10067
933093006655	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
933093006656	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093006657	putative substrate translocation pore; other site
933093006658	Lipoproteins [Cell envelope biogenesis, outer membrane]; Region: RlpA; COG0797
933093006659	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
933093006660	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
933093006661	active site
933093006662	motif I; other site
933093006663	motif II; other site
933093006664	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
933093006665	Catalytic domain of Protein Kinases; Region: PKc; cd00180
933093006666	active site
933093006667	ATP binding site [chemical binding]; other site
933093006668	substrate binding site [chemical binding]; other site
933093006669	activation loop (A-loop); other site
933093006670	PAS domain; Region: PAS_9; pfam13426
933093006671	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
933093006672	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
933093006673	DNA binding residues [nucleotide binding]
933093006674	dimerization interface [polypeptide binding]; other site
933093006675	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
933093006676	DNA binding site [nucleotide binding]
933093006677	active site
933093006678	Int/Topo IB signature motif; other site
933093006679	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
933093006680	Divergent AAA domain; Region: AAA_4; pfam04326
933093006681	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
933093006682	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
933093006683	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
933093006684	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
933093006685	non-specific DNA binding site [nucleotide binding]; other site
933093006686	salt bridge; other site
933093006687	sequence-specific DNA binding site [nucleotide binding]; other site
933093006688	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
933093006689	Catalytic site [active]
933093006690	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; cl17523
933093006691	Transposase; Region: HTH_Tnp_1; pfam01527
933093006692	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
933093006693	HTH-like domain; Region: HTH_21; pfam13276
933093006694	Integrase core domain; Region: rve; pfam00665
933093006695	Integrase core domain; Region: rve_3; pfam13683
933093006696	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
933093006697	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
933093006698	non-specific DNA binding site [nucleotide binding]; other site
933093006699	salt bridge; other site
933093006700	sequence-specific DNA binding site [nucleotide binding]; other site
933093006701	multiple promoter invertase; Provisional; Region: mpi; PRK13413
933093006702	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
933093006703	catalytic residues [active]
933093006704	catalytic nucleophile [active]
933093006705	Presynaptic Site I dimer interface [polypeptide binding]; other site
933093006706	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
933093006707	Synaptic Flat tetramer interface [polypeptide binding]; other site
933093006708	Synaptic Site I dimer interface [polypeptide binding]; other site
933093006709	DNA binding site [nucleotide binding]
933093006710	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
933093006711	DNA-binding interface [nucleotide binding]; DNA binding site
933093006712	Protein of unknown function (DUF1653); Region: DUF1653; pfam07866
933093006713	Uncharacterized conserved protein [Function unknown]; Region: COG3189
933093006714	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
933093006715	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
933093006716	active site
933093006717	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
933093006718	tetramer interface [polypeptide binding]; other site
933093006719	TPP-binding site [chemical binding]; other site
933093006720	heterodimer interface [polypeptide binding]; other site
933093006721	phosphorylation loop region [posttranslational modification]
933093006722	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
933093006723	Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Region: TPP_enzyme_PYR; cl11410
933093006724	PYR/PP interface [polypeptide binding]; other site
933093006725	dimer interface [polypeptide binding]; other site
933093006726	TPP binding site [chemical binding]; other site
933093006727	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
933093006728	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
933093006729	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
933093006730	D-ala-D-ala dipeptidase; Region: Peptidase_M15; cl00813
933093006731	C1 Peptidase family (MEROPS database nomenclature), also referred to as the papain family; composed of two subfamilies of cysteine peptidases (CPs), C1A (papain) and C1B (bleomycin hydrolase). Papain-like enzymes are mostly endopeptidases with some...; Region: Peptidase_C1; cd02619
933093006732	active site
933093006733	Fatty acyltransferase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: fatty_acyltransferase_like; cd01846
933093006734	active site
933093006735	catalytic triad [active]
933093006736	oxyanion hole [active]
933093006737	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
933093006738	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
933093006739	active site
933093006740	metal binding site [ion binding]; metal-binding site
933093006741	D-Ala-D-Ala carboxypeptidase 3 (S13) family; Region: Peptidase_S13; cl17429
933093006742	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
933093006743	ParB-like nuclease domain; Region: ParBc; pfam02195
933093006744	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
933093006745	16S rRNA methyltransferase B; Provisional; Region: PRK10901
933093006746	RNA binding domain of NusB (N protein-Utilization Substance B) and Sun (also known as RrmB or Fmu) proteins. This family includes two orthologous groups exemplified by the transcription termination factor NusB and the N-terminal domain of the...; Region: NusB_Sun; cl00223
933093006747	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
933093006748	S-adenosylmethionine binding site [chemical binding]; other site
933093006749	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
933093006750	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
933093006751	putative active site [active]
933093006752	substrate binding site [chemical binding]; other site
933093006753	putative cosubstrate binding site; other site
933093006754	catalytic site [active]
933093006755	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
933093006756	substrate binding site [chemical binding]; other site
933093006757	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
933093006758	active site
933093006759	catalytic residues [active]
933093006760	metal binding site [ion binding]; metal-binding site
933093006761	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
933093006762	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758
933093006763	DNA protecting protein DprA; Region: dprA; TIGR00732
933093006764	Protein of unknown function (DUF494); Region: DUF494; cl01103
933093006765	DNA topoisomerase I; Validated; Region: PRK06599
933093006766	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
933093006767	active site
933093006768	interdomain interaction site; other site
933093006769	putative metal-binding site [ion binding]; other site
933093006770	nucleotide binding site [chemical binding]; other site
933093006771	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
933093006772	domain I; other site
933093006773	DNA binding groove [nucleotide binding]
933093006774	phosphate binding site [ion binding]; other site
933093006775	domain II; other site
933093006776	domain III; other site
933093006777	nucleotide binding site [chemical binding]; other site
933093006778	catalytic site [active]
933093006779	domain IV; other site
933093006780	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
933093006781	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
933093006782	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
933093006783	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
933093006784	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
933093006785	Bacterial PH domain; Region: DUF304; pfam03703
933093006786	Protein of unknown function (DUF721); Region: DUF721; pfam05258
933093006787	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
933093006788	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
933093006789	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
933093006790	Uncharacterized conserved protein [Function unknown]; Region: COG4278
933093006791	ergothioneine biosynthesis protein EgtC; Region: TIGR03442
933093006792	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
933093006793	putative active site [active]
933093006794	putative dimer interface [polypeptide binding]; other site
933093006795	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
933093006796	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
933093006797	active site
933093006798	Zn binding site [ion binding]; other site
933093006799	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
933093006800	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
933093006801	cell division protein FtsZ; Validated; Region: PRK09330
933093006802	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
933093006803	nucleotide binding site [chemical binding]; other site
933093006804	SulA interaction site; other site
933093006805	cell division protein FtsA; Region: ftsA; TIGR01174
933093006806	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
933093006807	nucleotide binding site [chemical binding]; other site
933093006808	Cell division protein FtsA; Region: FtsA; pfam14450
933093006809	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
933093006810	Cell division protein FtsQ; Region: FtsQ; pfam03799
933093006811	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
933093006812	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
933093006813	ATP-grasp domain; Region: ATP-grasp_4; cl17255
933093006814	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
933093006815	FAD binding domain; Region: FAD_binding_4; pfam01565
933093006816	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
933093006817	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
933093006818	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
933093006819	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
933093006820	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
933093006821	cell division protein FtsW; Region: ftsW; TIGR02614
933093006822	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03803
933093006823	TrkA-N domain; Region: TrkA_N; pfam02254
933093006824	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
933093006825	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
933093006826	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
933093006827	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
933093006828	Mg++ binding site [ion binding]; other site
933093006829	putative catalytic motif [active]
933093006830	putative substrate binding site [chemical binding]; other site
933093006831	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
933093006832	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Region: murF; TIGR01143
933093006833	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
933093006834	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
933093006835	ZipA, C-terminal FtsZ-binding domain; Region: ZipA_C; pfam04354
933093006836	FtsZ protein binding site [polypeptide binding]; other site
933093006837	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
933093006838	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
933093006839	Walker A/P-loop; other site
933093006840	ATP binding site [chemical binding]; other site
933093006841	Q-loop/lid; other site
933093006842	SMC proteins Flexible Hinge Domain; Region: SMC_hinge; pfam06470
933093006843	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
933093006844	Q-loop/lid; other site
933093006845	ABC transporter signature motif; other site
933093006846	Walker B; other site
933093006847	D-loop; other site
933093006848	H-loop/switch region; other site
933093006849	HAD superfamily, subfamily IIIB (Acid phosphatase); Region: Acid_phosphat_B; pfam03767
933093006850	C1 Peptidase family (MEROPS database nomenclature), also referred to as the papain family; composed of two subfamilies of cysteine peptidases (CPs), C1A (papain) and C1B (bleomycin hydrolase). Papain-like enzymes are mostly endopeptidases with some...; Region: Peptidase_C1; cd02619
933093006851	active site
933093006852	Tim44 is an essential component of the machinery that mediates the translocation of nuclear-encoded proteins across the mitochondrial inner membrane; Region: Tim44; smart00978
933093006853	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
933093006854	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
933093006855	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
933093006856	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
933093006857	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
933093006858	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
933093006859	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
933093006860	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
933093006861	ATP-grasp domain; Region: ATP-grasp_4; cl17255
933093006862	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
933093006863	IMP binding site; other site
933093006864	dimer interface [polypeptide binding]; other site
933093006865	interdomain contacts; other site
933093006866	partial ornithine binding site; other site
933093006867	Predicted flavoproteins [General function prediction only]; Region: COG2081
933093006868	putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834
933093006869	Uncharacterized conserved protein [Function unknown]; Region: COG1434
933093006870	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
933093006871	putative active site [active]
933093006872	Predicted permeases [General function prediction only]; Region: COG0795; cl12074
933093006873	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
933093006874	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
933093006875	Predicted permeases [General function prediction only]; Region: COG0795
933093006876	multifunctional aminopeptidase A; Provisional; Region: PRK00913
933093006877	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
933093006878	interface (dimer of trimers) [polypeptide binding]; other site
933093006879	Substrate-binding/catalytic site; other site
933093006880	Zn-binding sites [ion binding]; other site
933093006881	DNA polymerase III chi subunit, HolC; Region: DNA_pol3_chi; pfam04364
933093006882	Domain of unknown function (DUF1840); Region: DUF1840; pfam08895
933093006883	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
933093006884	interface (dimer of trimers) [polypeptide binding]; other site
933093006885	Leucyl aminopeptidase [Amino acid transport and metabolism]; Region: PepB; COG0260
933093006886	Substrate-binding/catalytic site; other site
933093006887	Zn-binding sites [ion binding]; other site
933093006888	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
933093006889	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
933093006890	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
933093006891	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
933093006892	Sel1-like repeats; Region: SEL1; smart00671
933093006893	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
933093006894	Sel1-like repeats; Region: SEL1; smart00671
933093006895	Sel1-like repeats; Region: SEL1; smart00671
933093006896	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
933093006897	Sel1-like repeats; Region: SEL1; smart00671
933093006898	Sel1-like repeats; Region: SEL1; smart00671
933093006899	Sel1-like repeats; Region: SEL1; smart00671
933093006900	Sel1-like repeats; Region: SEL1; smart00671
933093006901	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
933093006902	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
933093006903	putative active site [active]
933093006904	GAF domain; Region: GAF; pfam01590
933093006905	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
933093006906	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
933093006907	metal binding site [ion binding]; metal-binding site
933093006908	active site
933093006909	I-site; other site
933093006910	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
933093006911	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
933093006912	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
933093006913	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
933093006914	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
933093006915	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
933093006916	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
933093006917	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
933093006918	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
933093006919	GIY-YIG motif/motif A; other site
933093006920	active site
933093006921	catalytic site [active]
933093006922	putative DNA binding site [nucleotide binding]; other site
933093006923	metal binding site [ion binding]; metal-binding site
933093006924	UvrB/uvrC motif; Region: UVR; pfam02151
933093006925	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
933093006926	response regulator; Provisional; Region: PRK09483
933093006927	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
933093006928	active site
933093006929	phosphorylation site [posttranslational modification]
933093006930	intermolecular recognition site; other site
933093006931	dimerization interface [polypeptide binding]; other site
933093006932	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
933093006933	DNA binding residues [nucleotide binding]
933093006934	dimerization interface [polypeptide binding]; other site
933093006935	Prokaryotic phenylalanine-4-hydroxylase (pro_PheOH); a member of the biopterin-dependent aromatic amino acid hydroxylase family of non-heme, iron(II)-dependent enzymes that also includes the eukaryotic proteins, phenylalanine-4-hydroxylase (eu_PheOH); Region: pro_PheOH; cd03348
933093006936	cofactor binding site; other site
933093006937	metal binding site [ion binding]; metal-binding site
933093006938	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
933093006939	competence damage-inducible protein A; Provisional; Region: PRK01215
933093006940	putative MPT binding site; other site
933093006941	GTPase CgtA; Reviewed; Region: obgE; PRK12299
933093006942	GTP1/OBG; Region: GTP1_OBG; pfam01018
933093006943	Obg GTPase; Region: Obg; cd01898
933093006944	G1 box; other site
933093006945	GTP/Mg2+ binding site [chemical binding]; other site
933093006946	Switch I region; other site
933093006947	G2 box; other site
933093006948	G3 box; other site
933093006949	Switch II region; other site
933093006950	G4 box; other site
933093006951	G5 box; other site
933093006952	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
933093006953	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
933093006954	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
933093006955	50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618
933093006956	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
933093006957	5S rRNA interface [nucleotide binding]; other site
933093006958	CTC domain interface [polypeptide binding]; other site
933093006959	L16 interface [polypeptide binding]; other site
933093006960	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
933093006961	putative active site [active]
933093006962	catalytic residue [active]
933093006963	GTP-binding protein YchF; Reviewed; Region: PRK09601
933093006964	YchF GTPase; Region: YchF; cd01900
933093006965	G1 box; other site
933093006966	GTP/Mg2+ binding site [chemical binding]; other site
933093006967	Switch I region; other site
933093006968	G2 box; other site
933093006969	Switch II region; other site
933093006970	G3 box; other site
933093006971	G4 box; other site
933093006972	G5 box; other site
933093006973	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
933093006974	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
933093006975	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
933093006976	metal binding site [ion binding]; metal-binding site
933093006977	active site
933093006978	I-site; other site
933093006979	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
933093006980	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
933093006981	substrate binding pocket [chemical binding]; other site
933093006982	chain length determination region; other site
933093006983	substrate-Mg2+ binding site; other site
933093006984	catalytic residues [active]
933093006985	aspartate-rich region 1; other site
933093006986	active site lid residues [active]
933093006987	aspartate-rich region 2; other site
933093006988	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
933093006989	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
933093006990	G1 box; other site
933093006991	GTP/Mg2+ binding site [chemical binding]; other site
933093006992	Switch I region; other site
933093006993	G2 box; other site
933093006994	G3 box; other site
933093006995	Switch II region; other site
933093006996	G4 box; other site
933093006997	G5 box; other site
933093006998	Nucleoside recognition; Region: Gate; pfam07670
933093006999	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
933093007000	Nucleoside recognition; Region: Gate; pfam07670
933093007001	FeoA domain; Region: FeoA; pfam04023
933093007002	Predicted ATPase [General function prediction only]; Region: COG1485
933093007003	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
933093007004	Walker A motif; other site
933093007005	ATP binding site [chemical binding]; other site
933093007006	Walker B motif; other site
933093007007	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2945
933093007008	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
933093007009	oligomerization interface [polypeptide binding]; other site
933093007010	active site
933093007011	metal binding site [ion binding]; metal-binding site
933093007012	pantoate--beta-alanine ligase; Region: panC; TIGR00018
933093007013	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
933093007014	active site
933093007015	nucleotide binding site [chemical binding]; other site
933093007016	HIGH motif; other site
933093007017	KMSKS motif; other site
933093007018	AAA domain; Region: AAA_28; pfam13521
933093007019	Predicted ATPase [General function prediction only]; Region: COG3911
933093007020	pyruvate carboxylase subunit A; Validated; Region: PRK07178
933093007021	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
933093007022	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
933093007023	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
933093007024	Dienelactone hydrolase family; Region: DLH; pfam01738
933093007025	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
933093007026	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
933093007027	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
933093007028	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
933093007029	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
933093007030	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
933093007031	DNA binding residues [nucleotide binding]
933093007032	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
933093007033	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
933093007034	Predicted ATPase involved in cell division [Cell division and chromosome partitioning]; Region: FtsE; COG2884
933093007035	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
933093007036	Walker A/P-loop; other site
933093007037	ATP binding site [chemical binding]; other site
933093007038	Q-loop/lid; other site
933093007039	ABC transporter signature motif; other site
933093007040	Walker B; other site
933093007041	D-loop; other site
933093007042	H-loop/switch region; other site
933093007043	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
933093007044	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
933093007045	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
933093007046	P loop; other site
933093007047	GTP binding site [chemical binding]; other site
933093007048	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
933093007049	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
933093007050	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
933093007051	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
933093007052	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
933093007053	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
933093007054	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
933093007055	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
933093007056	S-adenosylmethionine binding site [chemical binding]; other site
933093007057	Dot/Icm secretion system ATPase DotB; Region: dot_icm_DotB; TIGR02524
933093007058	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
933093007059	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
933093007060	Walker A motif; other site
933093007061	Walker A/P-loop; other site
933093007062	ATP binding site [chemical binding]; other site
933093007063	ATP binding site [chemical binding]; other site
933093007064	Walker B motif; other site
933093007065	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
933093007066	Bacillus subtilis YhcR endonuclease and related proteins, N-terminal metallophosphatase domain; Region: MPP_YhcR_N; cd07412
933093007067	putative active site [active]
933093007068	putative metal binding site [ion binding]; other site
933093007069	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
933093007070	Methyltransferase domain; Region: Methyltransf_23; pfam13489
933093007071	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
933093007072	S-adenosylmethionine binding site [chemical binding]; other site
933093007073	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
933093007074	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
933093007075	NAD binding site [chemical binding]; other site
933093007076	ATP-grasp domain; Region: ATP-grasp_4; cl17255
933093007077	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl07974
933093007078	active site
933093007079	catalytic residues [active]
933093007080	metal binding site [ion binding]; metal-binding site
933093007081	Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism]; Region: LeuB; COG0473
933093007082	tartrate dehydrogenase; Region: TTC; TIGR02089
933093007083	Demethylmenaquinone methyltransferase [Coenzyme metabolism]; Region: MenG; COG0684
933093007084	Dienelactone hydrolase family; Region: DLH; pfam01738
933093007085	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
933093007086	Phagosome trafficking protein DotA; Region: DotA; pfam11388
933093007087	conjugal transfer/type IV secretion protein DotA/TraY; Region: DotA_TraY; TIGR04346
933093007088	putative oxygen-independent coproporphyrinogen III oxidase; Region: hemN_rel; TIGR00539
933093007089	DNA polymerase type-B family catalytic domain. DNA-directed DNA polymerases elongate DNA by adding nucleotide triphosphate (dNTP) residues to the 5'-end of the growing chain of DNA. DNA-directed DNA polymerases are multifunctional with both...; Region: POLBc; cl10023
933093007090	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
933093007091	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
933093007092	metal-binding site [ion binding]
933093007093	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
933093007094	Methyltransferase domain; Region: Methyltransf_31; pfam13847
933093007095	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
933093007096	S-adenosylmethionine binding site [chemical binding]; other site
933093007097	Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; pfam05721
933093007098	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
933093007099	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
933093007100	putative active site [active]
933093007101	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
933093007102	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
933093007103	DNA mismatch repair protein MutL; Region: mutl; TIGR00585
933093007104	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
933093007105	ATP binding site [chemical binding]; other site
933093007106	Mg2+ binding site [ion binding]; other site
933093007107	G-X-G motif; other site
933093007108	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
933093007109	ATP binding site [chemical binding]; other site
933093007110	MutL C terminal dimerisation domain; Region: MutL_C; smart00853
933093007111	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
933093007112	AMIN domain; Region: AMIN; pfam11741
933093007113	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
933093007114	active site
933093007115	metal binding site [ion binding]; metal-binding site
933093007116	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
933093007117	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
933093007118	putative carbohydrate kinase; Provisional; Region: PRK10565
933093007119	Uncharacterized conserved protein [Function unknown]; Region: COG0062
933093007120	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
933093007121	putative substrate binding site [chemical binding]; other site
933093007122	putative ATP binding site [chemical binding]; other site
933093007123	ClpXP protease specificity-enhancing factor; Provisional; Region: PRK11798
933093007124	stringent starvation protein A; Provisional; Region: sspA; PRK09481
933093007125	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
933093007126	C-terminal domain interface [polypeptide binding]; other site
933093007127	putative GSH binding site (G-site) [chemical binding]; other site
933093007128	dimer interface [polypeptide binding]; other site
933093007129	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
933093007130	dimer interface [polypeptide binding]; other site
933093007131	N-terminal domain interface [polypeptide binding]; other site
933093007132	Cytochrome C1 family; Region: Cytochrom_C1; pfam02167
933093007133	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cd00284
933093007134	Qi binding site; other site
933093007135	intrachain domain interface; other site
933093007136	interchain domain interface [polypeptide binding]; other site
933093007137	cytochrome b; Validated; Region: CYTB; MTH00016
933093007138	heme bH binding site [chemical binding]; other site
933093007139	heme bL binding site [chemical binding]; other site
933093007140	Qo binding site; other site
933093007141	Cytochrome b(C-terminus)/b6/petD:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: cytochrome_b_C; cd00290
933093007142	interchain domain interface [polypeptide binding]; other site
933093007143	intrachain domain interface; other site
933093007144	Qi binding site; other site
933093007145	Qo binding site; other site
933093007146	Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal; Region: UCR_Fe-S_N; pfam10399
933093007147	ubiquinol-cytochrome c reductase, iron-sulfur subunit; Region: Rieske_proteo; TIGR01416
933093007148	Iron-sulfur protein (ISP) component of the bc(1) complex family, Rieske domain; The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. The bc(1) complex is a multisubunit enzyme found in many different organisms including...; Region: Rieske_cytochrome_bc1; cd03470
933093007149	[2Fe-2S] cluster binding site [ion binding]; other site
933093007150	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
933093007151	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
933093007152	23S rRNA interface [nucleotide binding]; other site
933093007153	L3 interface [polypeptide binding]; other site
933093007154	Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:...; Region: TRX_Fd_family; cd02980
933093007155	dimer interface [polypeptide binding]; other site
933093007156	[2Fe-2S] cluster binding site [ion binding]; other site
933093007157	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
933093007158	IHF - DNA interface [nucleotide binding]; other site
933093007159	IHF dimer interface [polypeptide binding]; other site
933093007160	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
933093007161	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
933093007162	putative tRNA-binding site [nucleotide binding]; other site
933093007163	B3/4 domain; Region: B3_4; pfam03483
933093007164	tRNA synthetase B5 domain; Region: B5; pfam03484
933093007165	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
933093007166	dimer interface [polypeptide binding]; other site
933093007167	motif 1; other site
933093007168	motif 3; other site
933093007169	motif 2; other site
933093007170	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
933093007171	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
933093007172	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
933093007173	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
933093007174	dimer interface [polypeptide binding]; other site
933093007175	motif 1; other site
933093007176	active site
933093007177	motif 2; other site
933093007178	motif 3; other site
933093007179	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
933093007180	23S rRNA binding site [nucleotide binding]; other site
933093007181	L21 binding site [polypeptide binding]; other site
933093007182	L13 binding site [polypeptide binding]; other site
933093007183	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
933093007184	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
933093007185	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
933093007186	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
933093007187	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
933093007188	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
933093007189	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
933093007190	active site
933093007191	dimer interface [polypeptide binding]; other site
933093007192	motif 1; other site
933093007193	motif 2; other site
933093007194	motif 3; other site
933093007195	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
933093007196	anticodon binding site; other site
933093007197	Uncharacterized ACR, YggU family COG1872; Region: DUF167; pfam02594
933093007198	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
933093007199	non-specific DNA binding site [nucleotide binding]; other site
933093007200	salt bridge; other site
933093007201	sequence-specific DNA binding site [nucleotide binding]; other site
933093007202	gamma-glutamyl:cysteine ligase; Provisional; Region: PRK13516
933093007203	carboxylate-amine ligase, YbdK family; Region: gshA_cyan_rel; TIGR02050
933093007204	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
933093007205	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
933093007206	ligand binding site [chemical binding]; other site
933093007207	flexible hinge region; other site
933093007208	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
933093007209	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
933093007210	ligand binding site [chemical binding]; other site
933093007211	flexible hinge region; other site
933093007212	ergothioneine biosynthesis protein EgtC; Region: TIGR03442
933093007213	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
933093007214	putative active site [active]
933093007215	putative dimer interface [polypeptide binding]; other site
933093007216	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
933093007217	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
933093007218	FMN binding site [chemical binding]; other site
933093007219	active site
933093007220	substrate binding site [chemical binding]; other site
933093007221	catalytic residue [active]
933093007222	Predicted membrane protein [Function unknown]; Region: COG2860
933093007223	UPF0126 domain; Region: UPF0126; pfam03458
933093007224	UPF0126 domain; Region: UPF0126; pfam03458
933093007225	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
933093007226	substrate binding site [chemical binding]; other site
933093007227	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
933093007228	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; cl00409
933093007229	Cytochrome c5 [Energy production and conversion]; Region: CycB; COG3245
933093007230	hypothetical protein; Provisional; Region: PRK07179
933093007231	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
933093007232	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
933093007233	catalytic residue [active]
933093007234	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
933093007235	active site
933093007236	phosphorylation site [posttranslational modification]
933093007237	intermolecular recognition site; other site
933093007238	Uncharacterized conserved protein [Function unknown]; Region: HdeD; COG3247
933093007239	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
933093007240	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
933093007241	ATP binding site [chemical binding]; other site
933093007242	Mg2+ binding site [ion binding]; other site
933093007243	G-X-G motif; other site
933093007244	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
933093007245	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
933093007246	domain interfaces; other site
933093007247	active site
933093007248	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
933093007249	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
933093007250	active site
933093007251	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
933093007252	heme biosynthesis-associated TPR protein; Region: TPR_hemY_coli; TIGR00540
933093007253	HemY protein N-terminus; Region: HemY_N; pfam07219
933093007254	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
933093007255	TPR motif; other site
933093007256	binding surface
933093007257	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
933093007258	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
933093007259	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1636
933093007260	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
933093007261	catalytic site [active]
933093007262	putative active site [active]
933093007263	putative substrate binding site [chemical binding]; other site
933093007264	dimer interface [polypeptide binding]; other site
933093007265	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
933093007266	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
933093007267	active site
933093007268	NTP binding site [chemical binding]; other site
933093007269	metal binding triad [ion binding]; metal-binding site
933093007270	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
933093007271	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
933093007272	Zn2+ binding site [ion binding]; other site
933093007273	Mg2+ binding site [ion binding]; other site
933093007274	GTPase RsgA; Reviewed; Region: PRK12288
933093007275	S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466
933093007276	RNA binding site [nucleotide binding]; other site
933093007277	homodimer interface [polypeptide binding]; other site
933093007278	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
933093007279	GTPase/Zn-binding domain interface [polypeptide binding]; other site
933093007280	GTP/Mg2+ binding site [chemical binding]; other site
933093007281	G4 box; other site
933093007282	G5 box; other site
933093007283	G1 box; other site
933093007284	Switch I region; other site
933093007285	G2 box; other site
933093007286	G3 box; other site
933093007287	Switch II region; other site
933093007288	potential protein location (hypothetical protein lp12_2740 [Legionella pneumophila subsp. pneumophila ATCC 43290]) that overlaps RNA (23S ribosomal RNA)
933093007289	potential protein location (hypothetical protein lp12_2741 [Legionella pneumophila subsp. pneumophila ATCC 43290]) that overlaps RNA (23S ribosomal RNA)
933093007290	potential protein location (hypothetical protein lp12_2742 [Legionella pneumophila subsp. pneumophila ATCC 43290]) that overlaps RNA (23S ribosomal RNA)
933093007291	DNA polymerase III subunits gamma and tau; Provisional; Region: PRK14969
933093007292	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
933093007293	Walker A motif; other site
933093007294	ATP binding site [chemical binding]; other site
933093007295	Walker B motif; other site
933093007296	arginine finger; other site
933093007297	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
933093007298	hypothetical protein; Validated; Region: PRK00153
933093007299	recombination protein RecR; Reviewed; Region: recR; PRK00076
933093007300	RecR protein; Region: RecR; pfam02132
933093007301	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
933093007302	putative active site [active]
933093007303	putative metal-binding site [ion binding]; other site
933093007304	tetramer interface [polypeptide binding]; other site
933093007305	Protein of unknown function, DUF547; Region: DUF547; pfam04784
933093007306	Sulfatase; Region: Sulfatase; cl17466
933093007307	phosphate regulon transcriptional regulatory protein PhoB; Region: PhoB; TIGR02154
933093007308	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
933093007309	active site
933093007310	dimerization interface [polypeptide binding]; other site
933093007311	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
933093007312	DNA binding site [nucleotide binding]
933093007313	Putative Mg2+ and Co2+ transporter CorB [Inorganic ion transport and metabolism]; Region: CorB; COG4536
933093007314	Domain of unknown function DUF21; Region: DUF21; pfam01595
933093007315	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
933093007316	Transporter associated domain; Region: CorC_HlyC; smart01091
933093007317	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
933093007318	dimer interface [polypeptide binding]; other site
933093007319	substrate binding site [chemical binding]; other site
933093007320	metal binding sites [ion binding]; metal-binding site
933093007321	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
933093007322	nucleotide binding site/active site [active]
933093007323	HIT family signature motif; other site
933093007324	catalytic residue [active]
933093007325	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
933093007326	GTP cyclohydrolase I; Provisional; Region: PLN03044
933093007327	homodecamer interface [polypeptide binding]; other site
933093007328	active site
933093007329	putative catalytic site residues [active]
933093007330	zinc binding site [ion binding]; other site
933093007331	GTP-CH-I/GFRP interaction surface; other site
933093007332	Glucose/sorbosone dehydrogenases [Carbohydrate transport and metabolism]; Region: COG2133
933093007333	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
933093007334	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
933093007335	RNase E interface [polypeptide binding]; other site
933093007336	trimer interface [polypeptide binding]; other site
933093007337	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
933093007338	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
933093007339	RNase E interface [polypeptide binding]; other site
933093007340	trimer interface [polypeptide binding]; other site
933093007341	active site
933093007342	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
933093007343	putative nucleic acid binding region [nucleotide binding]; other site
933093007344	G-X-X-G motif; other site
933093007345	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
933093007346	RNA binding site [nucleotide binding]; other site
933093007347	domain interface; other site
933093007348	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
933093007349	16S/18S rRNA binding site [nucleotide binding]; other site
933093007350	S13e-L30e interaction site [polypeptide binding]; other site
933093007351	25S rRNA binding site [nucleotide binding]; other site
933093007352	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
933093007353	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
933093007354	RNA binding site [nucleotide binding]; other site
933093007355	active site
933093007356	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
933093007357	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
933093007358	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
933093007359	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
933093007360	translation initiation factor IF-2; Region: IF-2; TIGR00487
933093007361	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
933093007362	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
933093007363	G1 box; other site
933093007364	putative GEF interaction site [polypeptide binding]; other site
933093007365	GTP/Mg2+ binding site [chemical binding]; other site
933093007366	Switch I region; other site
933093007367	G2 box; other site
933093007368	G3 box; other site
933093007369	Switch II region; other site
933093007370	G4 box; other site
933093007371	G5 box; other site
933093007372	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
933093007373	Translation-initiation factor 2; Region: IF-2; pfam11987
933093007374	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
933093007375	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
933093007376	NusA N-terminal domain; Region: NusA_N; pfam08529
933093007377	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
933093007378	RNA binding site [nucleotide binding]; other site
933093007379	homodimer interface [polypeptide binding]; other site
933093007380	NusA-like KH domain; Region: KH_5; pfam13184
933093007381	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
933093007382	G-X-X-G motif; other site
933093007383	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
933093007384	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
933093007385	ribosome maturation protein RimP; Reviewed; Region: PRK00092
933093007386	Sm and related proteins; Region: Sm_like; cl00259
933093007387	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
933093007388	putative oligomer interface [polypeptide binding]; other site
933093007389	putative RNA binding site [nucleotide binding]; other site
933093007390	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
933093007391	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
933093007392	proton-translocating NADH-quinone oxidoreductase, chain M; Region: NDH_I_M; TIGR01972
933093007393	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
933093007394	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
933093007395	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
933093007396	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
933093007397	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
933093007398	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
933093007399	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
933093007400	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
933093007401	4Fe-4S binding domain; Region: Fer4; cl02805
933093007402	4Fe-4S binding domain; Region: Fer4; pfam00037
933093007403	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
933093007404	NADH dehydrogenase subunit G; Validated; Region: PRK09129
933093007405	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
933093007406	catalytic loop [active]
933093007407	iron binding site [ion binding]; other site
933093007408	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
933093007409	MopB_NDH-1_NuoG2: The second domain of the NuoG subunit of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1), found in beta- and gammaproteobacteria. The NDH-1 is the first energy-transducting complex in the respiratory chain and functions as...; Region: MopB_NDH-1_NuoG2; cd02772
933093007410	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cl09929
933093007411	NADH-quinone oxidoreductase, F subunit; Region: nuoF_fam; TIGR01959
933093007412	SLBB domain; Region: SLBB; pfam10531
933093007413	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; smart00928
933093007414	NADH dehydrogenase subunit E; Validated; Region: PRK07539
933093007415	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
933093007416	putative dimer interface [polypeptide binding]; other site
933093007417	[2Fe-2S] cluster binding site [ion binding]; other site
933093007418	NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion]; Region: NuoD; COG0649
933093007419	NADH dehydrogenase subunit D; Validated; Region: PRK06075
933093007420	NADH dehydrogenase subunit C; Provisional; Region: PRK06074
933093007421	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
933093007422	NADH dehydrogenase subunit B; Validated; Region: PRK06411
933093007423	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
933093007424	Preprotein translocase SecG subunit; Region: SecG; pfam03840
933093007425	triosephosphate isomerase; Provisional; Region: PRK14567
933093007426	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
933093007427	substrate binding site [chemical binding]; other site
933093007428	dimer interface [polypeptide binding]; other site
933093007429	catalytic triad [active]
933093007430	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
933093007431	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
933093007432	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
933093007433	active site
933093007434	substrate binding site [chemical binding]; other site
933093007435	metal binding site [ion binding]; metal-binding site
933093007436	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
933093007437	dihydropteroate synthase; Region: DHPS; TIGR01496
933093007438	substrate binding pocket [chemical binding]; other site
933093007439	dimer interface [polypeptide binding]; other site
933093007440	inhibitor binding site; inhibition site
933093007441	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
933093007442	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
933093007443	Walker A motif; other site
933093007444	ATP binding site [chemical binding]; other site
933093007445	Walker B motif; other site
933093007446	arginine finger; other site
933093007447	Peptidase family M41; Region: Peptidase_M41; pfam01434
933093007448	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
933093007449	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
933093007450	S-adenosylmethionine binding site [chemical binding]; other site
933093007451	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
933093007452	IucA / IucC family; Region: IucA_IucC; pfam04183
933093007453	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
933093007454	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
933093007455	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
933093007456	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
933093007457	Walker A motif; other site
933093007458	ATP binding site [chemical binding]; other site
933093007459	Walker B motif; other site
933093007460	arginine finger; other site
933093007461	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
933093007462	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093007463	putative substrate translocation pore; other site
933093007464	POT family; Region: PTR2; cl17359
933093007465	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
933093007466	Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396
933093007467	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
933093007468	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
933093007469	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
933093007470	shikimate binding site; other site
933093007471	NAD(P) binding site [chemical binding]; other site
933093007472	aminopeptidase N; Provisional; Region: pepN; PRK14015
933093007473	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
933093007474	active site
933093007475	Zn binding site [ion binding]; other site
933093007476	PrkA family serine protein kinase; Provisional; Region: PRK15455
933093007477	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
933093007478	PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798
933093007479	hypothetical protein; Provisional; Region: PRK05325
933093007480	SpoVR family protein; Provisional; Region: PRK11767
933093007481	Uncharacterized conserved protein [Function unknown]; Region: SpoVR; COG2719
933093007482	M28 Zn-Peptidase Aeromonas (Vibrio) proteolytica aminopeptidase; Region: M28_AAP; cd03879
933093007483	Peptidase family M28; Region: Peptidase_M28; pfam04389
933093007484	active site
933093007485	metal binding site [ion binding]; metal-binding site
933093007486	ATP-dependent DNA helicase Rep; Region: rep; TIGR01074
933093007487	Part of AAA domain; Region: AAA_19; pfam13245
933093007488	Family description; Region: UvrD_C_2; pfam13538
933093007489	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
933093007490	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
933093007491	dimerization interface [polypeptide binding]; other site
933093007492	domain crossover interface; other site
933093007493	redox-dependent activation switch; other site
933093007494	Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; Region: PTPc; cl00053
933093007495	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
933093007496	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
933093007497	active site
933093007498	catalytic tetrad [active]
933093007499	YjeF-related protein N-terminus; Region: YjeF_N; pfam03853
933093007500	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
933093007501	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
933093007502	G1 box; other site
933093007503	putative GEF interaction site [polypeptide binding]; other site
933093007504	GTP/Mg2+ binding site [chemical binding]; other site
933093007505	Switch I region; other site
933093007506	G2 box; other site
933093007507	G3 box; other site
933093007508	Switch II region; other site
933093007509	G4 box; other site
933093007510	G5 box; other site
933093007511	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
933093007512	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
933093007513	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK01231
933093007514	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
933093007515	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
933093007516	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
933093007517	Walker A/P-loop; other site
933093007518	ATP binding site [chemical binding]; other site
933093007519	Q-loop/lid; other site
933093007520	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
933093007521	ABC transporter signature motif; other site
933093007522	Walker B; other site
933093007523	D-loop; other site
933093007524	H-loop/switch region; other site
933093007525	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
933093007526	DNA-binding site [nucleotide binding]; DNA binding site
933093007527	RNA-binding motif; other site
933093007528	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
933093007529	conserved cys residue [active]
933093007530	Uncharacterized protein conserved in bacteria containing a pentein-type domain [Function unknown]; Region: COG4874
933093007531	Amidinotransferase; Region: Amidinotransf; pfam02274
933093007532	U-box domain; Region: U-box; cl17544
933093007533	U-box domain; Region: U-box; cl17544
933093007534	ExoU and VipD-like proteins; homologus to patatin, cPLA2, and iPLA2; Region: Pat_ExoU_VipD_like; cd07207
933093007535	active site
933093007536	nucleophile elbow; other site
933093007537	ExoU and VipD-like proteins; homologus to patatin, cPLA2, and iPLA2; Region: Pat_ExoU_VipD_like; cd07207
933093007538	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
933093007539	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
933093007540	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
933093007541	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
933093007542	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
933093007543	RNA binding site [nucleotide binding]; other site
933093007544	thiopurine S-methyltransferase; Reviewed; Region: PRK13255
933093007545	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
933093007546	S-adenosylmethionine binding site [chemical binding]; other site
933093007547	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
933093007548	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
933093007549	glutaminase active site [active]
933093007550	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
933093007551	dimer interface [polypeptide binding]; other site
933093007552	active site
933093007553	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
933093007554	dimer interface [polypeptide binding]; other site
933093007555	active site
933093007556	Phospholipase/lecithinase/hemolysin [Lipid metabolism / General function prediction only]; Region: COG3240
933093007557	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
933093007558	Fatty acyltransferase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: fatty_acyltransferase_like; cd01846
933093007559	active site
933093007560	oxyanion hole [active]
933093007561	catalytic triad [active]
933093007562	rhodanese superfamily protein; Provisional; Region: PRK05320
933093007563	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
933093007564	active site residue [active]
933093007565	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
933093007566	SmpB-tmRNA interface; other site
933093007567	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
933093007568	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
933093007569	catalytic triad [active]
933093007570	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
933093007571	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
933093007572	putative substrate translocation pore; other site
933093007573	NYN ribonuclease and ATPase of PhoH family domains [General    function prediction only]; Region: COG1875
933093007574	PIN domain of bacterial Smg6-like homologs with PhoH-like ATPase domains; Region: PIN_PhoHL-ATPase; cd09883
933093007575	putative active site [active]
933093007576	PhoH-like protein; Region: PhoH; pfam02562
933093007577	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
933093007578	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
933093007579	active site
933093007580	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
933093007581	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
933093007582	Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far.  This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases).  Plant T2 RNases are expressed during leaf...; Region: RNase_T2_prok; cd01062
933093007583	B1 nucleotide binding pocket [chemical binding]; other site
933093007584	B2 nucleotide binding pocket [chemical binding]; other site
933093007585	CAS motifs; other site
933093007586	active site
933093007587	TPR repeat; Region: TPR_11; pfam13414
933093007588	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
933093007589	TPR motif; other site
933093007590	Anaphase-promoting complex, cyclosome, subunit 3; Region: Apc3; pfam12895
933093007591	Methyltransferase domain; Region: Methyltransf_24; pfam13578
933093007592	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
933093007593	DNA-binding site [nucleotide binding]; DNA binding site
933093007594	RNA-binding motif; other site
933093007595	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
933093007596	Flavin containing amine oxidoreductase; Region: Amino_oxidase; pfam01593
933093007597	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
933093007598	Amidase; Region: Amidase; cl11426
933093007599	Oxygen tolerance; Region: BatD; pfam13584
933093007600	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
933093007601	binding surface
933093007602	TPR motif; other site
933093007603	Tetratricopeptide repeat; Region: TPR_16; pfam13432
933093007604	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
933093007605	metal ion-dependent adhesion site (MIDAS); other site
933093007606	VWA BatA type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_BatA_type; cd01467
933093007607	metal ion-dependent adhesion site (MIDAS); other site
933093007608	Protein of unknown function DUF58; Region: DUF58; pfam01882
933093007609	MoxR-like ATPases [General function prediction only]; Region: COG0714
933093007610	ATPase family associated with various cellular activities (AAA); Region: AAA_3; pfam07726
933093007611	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
933093007612	FMN binding site [chemical binding]; other site
933093007613	active site
933093007614	catalytic residues [active]
933093007615	substrate binding site [chemical binding]; other site
933093007616	pteridine reductase; Provisional; Region: PRK09135
933093007617	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
933093007618	NAD(P) binding site [chemical binding]; other site
933093007619	active site
933093007620	Uncharacterized conserved protein [Function unknown]; Region: COG1565
933093007621	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
933093007622	primosome assembly protein PriA; Validated; Region: PRK05580
933093007623	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
933093007624	ATP binding site [chemical binding]; other site
933093007625	putative Mg++ binding site [ion binding]; other site
933093007626	nucleotide binding region [chemical binding]; other site
933093007627	helicase superfamily c-terminal domain; Region: HELICc; smart00490
933093007628	ATP-binding site [chemical binding]; other site
933093007629	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
933093007630	active site
933093007631	thymidylate synthase; Reviewed; Region: thyA; PRK01827
933093007632	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
933093007633	dimerization interface [polypeptide binding]; other site
933093007634	active site
933093007635	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
933093007636	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
933093007637	Signal transduction protein containing GAF and PtsI domains [Signal transduction mechanisms]; Region: PtsP; COG3605
933093007638	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
933093007639	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
933093007640	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
933093007641	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
933093007642	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
933093007643	putative active site [active]
933093007644	Ap4A binding site [chemical binding]; other site
933093007645	nudix motif; other site
933093007646	putative metal binding site [ion binding]; other site
933093007647	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
933093007648	active site
933093007649	homodimer interface [polypeptide binding]; other site
933093007650	N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) [Cell envelope biogenesis, outer membrane]; Region: GlmU; COG1207
933093007651	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
933093007652	Substrate binding site; other site
933093007653	Mg++ binding site; other site
933093007654	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
933093007655	active site
933093007656	substrate binding site [chemical binding]; other site
933093007657	CoA binding site [chemical binding]; other site
933093007658	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
933093007659	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
933093007660	transmembrane helices; other site
933093007661	Uncharacterized ACR, YhhQ family COG1738; Region: DUF165; pfam02592
933093007662	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
933093007663	Thermotoga maritima CorA_like subfamily; Region: TmCorA-like_1; cd12828
933093007664	oligomer interface [polypeptide binding]; other site
933093007665	metal binding site [ion binding]; metal-binding site
933093007666	metal binding site [ion binding]; metal-binding site
933093007667	Cl binding site [ion binding]; other site
933093007668	aspartate ring; other site
933093007669	basic sphincter; other site
933093007670	putative hydrophobic gate; other site
933093007671	periplasmic entrance; other site
933093007672	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
933093007673	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
933093007674	minor groove reading motif; other site
933093007675	helix-hairpin-helix signature motif; other site
933093007676	substrate binding pocket [chemical binding]; other site
933093007677	active site
933093007678	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
933093007679	ferredoxin; Provisional; Region: PRK08764
933093007680	Putative Fe-S cluster; Region: FeS; pfam04060
933093007681	4Fe-4S binding domain; Region: Fer4; pfam00037
933093007682	4Fe-4S binding domain; Region: Fer4; cl02805
933093007683	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
933093007684	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
933093007685	active site
933093007686	HIGH motif; other site
933093007687	KMSKS motif; other site
933093007688	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
933093007689	anticodon binding site; other site
933093007690	tRNA binding surface [nucleotide binding]; other site
933093007691	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
933093007692	dimer interface [polypeptide binding]; other site
933093007693	putative tRNA-binding site [nucleotide binding]; other site
933093007694	polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases; Region: ubiX_pad; TIGR00421
933093007695	Flavoprotein; Region: Flavoprotein; pfam02441
933093007696	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
933093007697	Ligand Binding Site [chemical binding]; other site
933093007698	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
933093007699	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
933093007700	Substrate binding site; other site
933093007701	Cupin domain; Region: Cupin_2; cl17218
933093007702	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
933093007703	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
933093007704	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
933093007705	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
933093007706	rRNA small subunit methyltransferase G; Region: GidB; pfam02527
933093007707	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
933093007708	S-adenosylmethionine binding site [chemical binding]; other site
933093007709	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
933093007710	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
933093007711	P-loop; other site
933093007712	Magnesium ion binding site [ion binding]; other site
933093007713	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
933093007714	Magnesium ion binding site [ion binding]; other site
933093007715	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
933093007716	ParB-like nuclease domain; Region: ParBc; pfam02195
933093007717	Cytochrome c oxidase subunit III.  Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of...; Region: Cyt_c_Oxidase_III; cd01665
933093007718	Subunit III/VIIa interface [polypeptide binding]; other site
933093007719	Phospholipid binding site [chemical binding]; other site
933093007720	Subunit I/III interface [polypeptide binding]; other site
933093007721	Subunit III/VIb interface [polypeptide binding]; other site
933093007722	Subunit III/VIa interface; other site
933093007723	Subunit III/Vb interface [polypeptide binding]; other site
933093007724	cytochrome C oxidase assembly protein; Provisional; Region: PRK05089
933093007725	Cytochrome C oxidase subunit I.  Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of...; Region: Cyt_c_Oxidase_I; cd01663
933093007726	Subunit I/III interface [polypeptide binding]; other site
933093007727	Cytochrome C and Quinol oxidase polypeptide I; Region: COX1; pfam00115
933093007728	D-pathway; other site
933093007729	Subunit I/VIIc interface [polypeptide binding]; other site
933093007730	Subunit I/IV interface [polypeptide binding]; other site
933093007731	Subunit I/II interface [polypeptide binding]; other site
933093007732	Low-spin heme (heme a) binding site [chemical binding]; other site
933093007733	Subunit I/VIIa interface [polypeptide binding]; other site
933093007734	Subunit I/VIa interface [polypeptide binding]; other site
933093007735	Dimer interface; other site
933093007736	Putative water exit pathway; other site
933093007737	Binuclear center (heme a3/CuB) [ion binding]; other site
933093007738	K-pathway; other site
933093007739	Subunit I/Vb interface [polypeptide binding]; other site
933093007740	Putative proton exit pathway; other site
933093007741	Subunit I/VIb interface; other site
933093007742	Subunit I/VIc interface [polypeptide binding]; other site
933093007743	Electron transfer pathway; other site
933093007744	Subunit I/VIIIb interface [polypeptide binding]; other site
933093007745	Subunit I/VIIb interface [polypeptide binding]; other site
933093007746	Cytochrome C oxidase subunit II, transmembrane domain; Region: COX2_TM; pfam02790
933093007747	cytochrome c oxidase subunit II; Provisional; Region: COX2; MTH00168
933093007748	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
933093007749	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
933093007750	Cytochrome c; Region: Cytochrom_C; pfam00034
933093007751	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
933093007752	Cytochrome c5 [Energy production and conversion]; Region: CycB; COG3245
933093007753	Cytochrome c5 [Energy production and conversion]; Region: CycB; COG3245
933093007754	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
933093007755	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
933093007756	Lysine efflux permease [General function prediction only]; Region: COG1279
933093007757	Domain of unknown function (DUF1841); Region: DUF1841; pfam08897
933093007758	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
933093007759	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
933093007760	S-adenosylmethionine binding site [chemical binding]; other site
933093007761	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
933093007762	SCP-2 sterol transfer family; Region: SCP2; pfam02036
933093007763	SCP-2 sterol transfer family; Region: SCP2; cl01225
933093007764	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
933093007765	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
933093007766	Sec-independent protein secretion pathway components [Intracellular trafficking and secretion]; Region: TatA; COG1826
933093007767	bifunctional methionine sulfoxide reductase B/A protein; Provisional; Region: PRK05550
933093007768	Conserved domain frequently associated with peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: COG0229; cl15841
933093007769	Peptide methionine sulfoxide reductase; Region: PMSR; cl00366
933093007770	Domain of unknown function (DUF4169); Region: DUF4169; pfam13770
933093007771	tyramine oxidase; Provisional; Region: tynA; PRK11504
933093007772	Copper amine oxidase, N2 domain; Region: Cu_amine_oxidN2; pfam02727
933093007773	Copper amine oxidase, N3 domain; Region: Cu_amine_oxidN3; pfam02728
933093007774	Copper amine oxidase, enzyme domain; Region: Cu_amine_oxid; pfam01179
933093007775	Serine carboxypeptidase; Region: Peptidase_S10; pfam00450
933093007776	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
933093007777	AAA domain; Region: AAA_14; pfam13173
933093007778	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
933093007779	non-specific DNA binding site [nucleotide binding]; other site
933093007780	salt bridge; other site
933093007781	sequence-specific DNA binding site [nucleotide binding]; other site
933093007782	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_3; pfam13738
933093007783	Transglycosylase SLT domain; Region: SLT_2; pfam13406
933093007784	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
933093007785	N-acetyl-D-glucosamine binding site [chemical binding]; other site
933093007786	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
933093007787	Beta-lactamase; Region: Beta-lactamase; pfam00144
933093007788	Nucleotidyltransferase substrate binding protein like; Region: NTase_sub_bind; pfam08780
933093007789	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
933093007790	active site
933093007791	NTP binding site [chemical binding]; other site
933093007792	metal binding triad [ion binding]; metal-binding site
933093007793	antibiotic binding site [chemical binding]; other site
933093007794	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
933093007795	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
933093007796	FtsX-like permease family; Region: FtsX; pfam02687
933093007797	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
933093007798	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
933093007799	Walker A/P-loop; other site
933093007800	ATP binding site [chemical binding]; other site
933093007801	Q-loop/lid; other site
933093007802	ABC transporter signature motif; other site
933093007803	Walker B; other site
933093007804	D-loop; other site
933093007805	H-loop/switch region; other site
933093007806	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
933093007807	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
933093007808	HlyD family secretion protein; Region: HlyD_3; pfam13437
933093007809	Outer membrane efflux protein; Region: OEP; pfam02321
933093007810	Outer membrane efflux protein; Region: OEP; pfam02321
933093007811	diadenosine tetraphosphatase; Reviewed; Region: apaH; PRK00166
933093007812	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
933093007813	active site
933093007814	metal binding site [ion binding]; metal-binding site
933093007815	integrating conjugative element relaxase, PFL_4751 family; Region: ICE_TraI_Pfluor; TIGR03760
933093007816	Protein of unknown function (DUF1528); Region: DUF1528; pfam07515
933093007817	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
933093007818	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
933093007819	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
933093007820	tetramerization interface [polypeptide binding]; other site
933093007821	active site
933093007822	Sec-independent protein translocase protein (TatC); Region: TatC; cl00521
933093007823	Hemimethylated DNA-binding protein YccV like; Region: YccV-like; pfam08755
933093007824	FMN reductase; Validated; Region: fre; PRK08051
933093007825	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
933093007826	FAD binding pocket [chemical binding]; other site
933093007827	FAD binding motif [chemical binding]; other site
933093007828	phosphate binding motif [ion binding]; other site
933093007829	beta-alpha-beta structure motif; other site
933093007830	NAD binding pocket [chemical binding]; other site
933093007831	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; cl00311
933093007832	transcription termination factor Rho; Provisional; Region: rho; PRK09376
933093007833	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
933093007834	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
933093007835	RNA binding site [nucleotide binding]; other site
933093007836	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
933093007837	multimer interface [polypeptide binding]; other site
933093007838	Walker A motif; other site
933093007839	ATP binding site [chemical binding]; other site
933093007840	Walker B motif; other site
933093007841	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
933093007842	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
933093007843	catalytic residues [active]
933093007844	16S ribosomal RNA methyltransferase RsmE; Provisional; Region: PRK11713
933093007845	RNA methyltransferase, RsmE family; Region: TIGR00046
933093007846	fumarate hydratase; Reviewed; Region: fumC; PRK00485
933093007847	Class II fumarases; Region: Fumarase_classII; cd01362
933093007848	active site
933093007849	tetramer interface [polypeptide binding]; other site
933093007850	Predicted neuraminidase (sialidase) [Carbohydrate transport and metabolism]; Region: COG4692
933093007851	BNR repeat-like domain; Region: BNR_2; pfam13088
933093007852	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
933093007853	putative acyl-acceptor binding pocket; other site
933093007854	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cl17185
933093007855	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
933093007856	putative acyl-acceptor binding pocket; other site
933093007857	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
933093007858	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
933093007859	active site
933093007860	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
933093007861	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
933093007862	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
933093007863	trimer interface [polypeptide binding]; other site
933093007864	active site
933093007865	UDP-GlcNAc binding site [chemical binding]; other site
933093007866	lipid binding site [chemical binding]; lipid-binding site
933093007867	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
933093007868	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
933093007869	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_HprK; cl00270
933093007870	active site
933093007871	nucleotide-binding site [chemical binding]; other site
933093007872	metal-binding site [ion binding]
933093007873	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
933093007874	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
933093007875	Walker A/P-loop; other site
933093007876	ATP binding site [chemical binding]; other site
933093007877	Q-loop/lid; other site
933093007878	ABC transporter signature motif; other site
933093007879	Walker B; other site
933093007880	D-loop; other site
933093007881	H-loop/switch region; other site
933093007882	Transglutaminase-like superfamily; Region: Transglut_core3; pfam13471
933093007883	Coenzyme PQQ synthesis protein D (PqqD); Region: PqqD; cl05126
933093007884	Glutamine amidotransferases class-II (GATase). The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, glutamine is hydrolyzed to glutamic acid and ammonia. This domain is related to...; Region: Gn_AT_II; cl00319
933093007885	active site
933093007886	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
933093007887	Ligand Binding Site [chemical binding]; other site
933093007888	Molecular Tunnel; other site
933093007889	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
933093007890	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
933093007891	dimer interface [polypeptide binding]; other site
933093007892	pyridoxal 5'-phosphate binding site [chemical binding]; other site
933093007893	catalytic residue [active]
933093007894	Histone methylation protein DOT1; Region: DOT1; pfam08123
933093007895	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
933093007896	IHF dimer interface [polypeptide binding]; other site
933093007897	IHF - DNA interface [nucleotide binding]; other site
933093007898	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
933093007899	trimer interface [polypeptide binding]; other site
933093007900	active site
933093007901	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
933093007902	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
933093007903	Membrane-bound serine protease (ClpP class) [Posttranslational modification, protein turnover, chaperones]; Region: NfeD; COG1030
933093007904	Nodulation formation efficiency D (NfeD) is a membrane-bound ClpP-class protease; Region: Clp_protease_NfeD_1; cd07020
933093007905	dimer interface [polypeptide binding]; other site
933093007906	active site residues [active]
933093007907	NfeD-like C-terminal, partner-binding; Region: NfeD; pfam01957
933093007908	Protein of unknown function (DUF3450); Region: DUF3450; pfam11932
933093007909	Legionella pneumophila major outer membrane protein precursor; Region: Legionella_OMP; pfam05150
933093007910	Legionella pneumophila major outer membrane protein precursor; Region: Legionella_OMP; pfam05150
933093007911	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
933093007912	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
933093007913	ligand binding site [chemical binding]; other site
933093007914	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
933093007915	active site
933093007916	substrate binding pocket [chemical binding]; other site
933093007917	dimer interface [polypeptide binding]; other site
933093007918	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
933093007919	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
933093007920	dimer interface [polypeptide binding]; other site
933093007921	catalytic site [active]
933093007922	putative active site [active]
933093007923	putative substrate binding site [chemical binding]; other site
933093007924	peroxidase; Provisional; Region: PRK15000
933093007925	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
933093007926	dimer interface [polypeptide binding]; other site
933093007927	decamer (pentamer of dimers) interface [polypeptide binding]; other site
933093007928	catalytic triad [active]
933093007929	peroxidatic and resolving cysteines [active]
933093007930	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
933093007931	putative GSH binding site [chemical binding]; other site
933093007932	catalytic residues [active]
933093007933	superoxide dismutase; Provisional; Region: PRK10543
933093007934	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
933093007935	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
933093007936	acetylornithine aminotransferase; Provisional; Region: PRK02627
933093007937	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
933093007938	inhibitor-cofactor binding pocket; inhibition site
933093007939	pyridoxal 5'-phosphate binding site [chemical binding]; other site
933093007940	catalytic residue [active]
933093007941	Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only]; Region: ElaC; COG1234
933093007942	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
933093007943	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
933093007944	active site
933093007945	catalytic site [active]
933093007946	malate dehydrogenase; Provisional; Region: PRK13529
933093007947	Malic enzyme, N-terminal domain; Region: malic; pfam00390
933093007948	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
933093007949	NAD(P) binding site [chemical binding]; other site
933093007950	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
933093007951	Putative GTP-binding controlling metal-binding; Region: SUA5; pfam03481
933093007952	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
933093007953	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
933093007954	Peptidase M4 family includes thermolysin, protealysin, aureolysin and neutral protease; Region: M4_neutral_protease; cd09597
933093007955	active site
933093007956	Zn binding site [ion binding]; other site
933093007957	Fungalysin/Thermolysin Propeptide Motif; Region: FTP; pfam07504
933093007958	Rossmann-like domain; Region: Rossmann-like; pfam10727
933093007959	Domain of unknown function (DUF2520); Region: DUF2520; pfam10728
933093007960	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
933093007961	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
933093007962	CAP-like domain; other site
933093007963	active site
933093007964	primary dimer interface [polypeptide binding]; other site
933093007965	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
933093007966	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
933093007967	gamma subunit interface [polypeptide binding]; other site
933093007968	LBP interface [polypeptide binding]; other site
933093007969	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
933093007970	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
933093007971	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
933093007972	alpha subunit interaction interface [polypeptide binding]; other site
933093007973	Walker A motif; other site
933093007974	ATP binding site [chemical binding]; other site
933093007975	Walker B motif; other site
933093007976	inhibitor binding site; inhibition site
933093007977	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
933093007978	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
933093007979	core domain interface [polypeptide binding]; other site
933093007980	delta subunit interface [polypeptide binding]; other site
933093007981	epsilon subunit interface [polypeptide binding]; other site
933093007982	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
933093007983	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
933093007984	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
933093007985	beta subunit interaction interface [polypeptide binding]; other site
933093007986	Walker A motif; other site
933093007987	ATP binding site [chemical binding]; other site
933093007988	Walker B motif; other site
933093007989	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
933093007990	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
933093007991	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
933093007992	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
933093007993	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
933093007994	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
933093007995	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
933093007996	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
933093007997	F0F1 ATP synthase subunit I; Validated; Region: PRK05760
933093007998	outer membrane lipoprotein; Provisional; Region: PRK11023
933093007999	BON domain; Region: BON; pfam04972
933093008000	Predicted periplasmic or secreted lipoprotein [General function prediction only]; Region: OsmY; COG2823
933093008001	BON domain; Region: BON; pfam04972
933093008002	BON domain; Region: BON; cl02771
933093008003	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
933093008004	dimer interface [polypeptide binding]; other site
933093008005	active site
933093008006	hypothetical protein; Reviewed; Region: PRK12497
933093008007	Putative lipoprotein [General function prediction only]; Region: LppC; COG3107
933093008008	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
933093008009	putative ligand binding site [chemical binding]; other site
933093008010	Predicted methyltransferases [General function prediction only]; Region: COG0313
933093008011	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
933093008012	putative SAM binding site [chemical binding]; other site
933093008013	putative homodimer interface [polypeptide binding]; other site
933093008014	Alkane hydroxylase is a bacterial, integral-membrane di-iron enzyme that shares a requirement for iron and oxygen for activity similar to that of the non-heme integral-membrane acyl coenzyme A (CoA) desaturases and acyl lipid desaturases. The alk genes...; Region: Alkane-hydroxylase; cd03512
933093008015	Fatty acid desaturase; Region: FA_desaturase; pfam00487
933093008016	Di-iron ligands [ion binding]; other site
933093008017	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
933093008018	Sulfate transporter family; Region: Sulfate_transp; pfam00916
933093008019	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
933093008020	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
933093008021	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
933093008022	ligand binding site [chemical binding]; other site
933093008023	flexible hinge region; other site
933093008024	Astacin (Peptidase family M12A); Region: Astacin; pfam01400
933093008025	Zinc-dependent metalloprotease, astacin_like subfamily or peptidase family M12A, a group of zinc-dependent proteolytic enzymes with a HExxH zinc-binding site/active site. Members of this family may have an amino terminal propeptide, which is cleaved to...; Region: ZnMc_astacin_like; cd04280
933093008026	active site
933093008027	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
933093008028	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
933093008029	Circularly permuted YlqF-related GTPases; Region: YlqF_related_GTPase; cl17249
933093008030	GTP/Mg2+ binding site [chemical binding]; other site
933093008031	G4 box; other site
933093008032	G5 box; other site
933093008033	trmE is a tRNA modification GTPase; Region: trmE; cd04164
933093008034	G1 box; other site
933093008035	G1 box; other site
933093008036	GTP/Mg2+ binding site [chemical binding]; other site
933093008037	Switch I region; other site
933093008038	Switch I region; other site
933093008039	G2 box; other site
933093008040	G2 box; other site
933093008041	Switch II region; other site
933093008042	G3 box; other site
933093008043	G4 box; other site
933093008044	G5 box; other site
933093008045	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
933093008046	membrane protein insertase; Provisional; Region: PRK01318
933093008047	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
933093008048	hypothetical protein; Provisional; Region: PRK14380
933093008049	Ribonuclease P; Region: Ribonuclease_P; cl00457
933093008050	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399